locus-tag	class	description
H7F25_00005	COG2113	Glycine betaine
H7F25_00010	COG0596	Alpha beta hydrolase
H7F25_00020	COG1473	amidohydrolase
H7F25_00025	COG1288	antiporter activity
H7F25_00030	COG0039	L-malate dehydrogenase activity
H7F25_00035	COG1620	l-lactate permease
H7F25_00040	COG1609	Transcriptional regulator
H7F25_00045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F25_00050	COG0561	phosphatase activity
H7F25_00055	COG0673	inositol 2-dehydrogenase activity
H7F25_00060	COG0738	Major facilitator superfamily
H7F25_00065	COG1280	lysine exporter protein (LysE YggA)
H7F25_00075	COG3403	YqcI/YcgG family
H7F25_00080	COG1113	amino acid transport
H7F25_00085	COG3665	Urea carboxylase-associated protein
H7F25_00090	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7F25_00100	COG1012	belongs to the aldehyde dehydrogenase family
H7F25_00105	COG0710	3-dehydroquinate dehydratase activity
H7F25_00110	COG0028	Belongs to the TPP enzyme family
H7F25_00120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F25_00125	COG2271	Major facilitator Superfamily
H7F25_00140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7F25_00145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F25_00150	COG1609	Transcriptional regulator
H7F25_00155	COG0477	Major facilitator Superfamily
H7F25_00160	COG2226	methyltransferase
H7F25_00165	COG0583	DNA-binding transcription factor activity
H7F25_00170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F25_00175	COG3458	cephalosporin-C deacetylase activity
H7F25_00185	COG3541	Predicted nucleotidyltransferase
H7F25_00190	COG0506	proline dehydrogenase activity
H7F25_00195	COG1012	belongs to the aldehyde dehydrogenase family
H7F25_00200	COG2508	Transcriptional regulator
H7F25_00205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7F25_00210	COG0765	amino acid transport
H7F25_00215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F25_00225	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F25_00230	COG1522	sequence-specific DNA binding
H7F25_00235	COG2746	aminoglycoside 3-N-acetyltransferase activity
H7F25_00245	COG3290	protein histidine kinase activity
H7F25_00245	COG0840	transmembrane signaling receptor activity
H7F25_00250	COG3209	COG3209 Rhs family protein
H7F25_00270	COG3842	ATPase activity
H7F25_00285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F25_00290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F25_00295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F25_00310	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H7F25_00315	COG0697	spore germination
H7F25_00320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F25_00335	COG2364	Membrane
H7F25_00340	COG1126	abc transporter atp-binding protein
H7F25_00345	COG0765	amino acid transport
H7F25_00350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F25_00355	COG0833	amino acid
H7F25_00365	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_00370	COG1312	Catalyzes the dehydration of D-mannonate
H7F25_00375	COG1802	Transcriptional regulator
H7F25_00380	COG0673	inositol 2-dehydrogenase activity
H7F25_00390	COG1904	glucuronate isomerase
H7F25_00395	COG3104	oligopeptide transport
H7F25_00400	COG5434	Belongs to the glycosyl hydrolase 28 family
H7F25_00405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F25_00410	COG0456	acetyltransferase
H7F25_00415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F25_00420	COG0765	amino acid transport
H7F25_00425	COG1126	abc transporter atp-binding protein
H7F25_00430	COG1473	amidohydrolase
H7F25_00435	COG2079	MmgE PrpD family protein
H7F25_00440	COG0745	RESPONSE REGULATOR receiver
H7F25_00445	COG3850	Histidine kinase
H7F25_00445	COG5002	protein histidine kinase activity
H7F25_00450	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F25_00455	COG0527	aspartate kinase activity
H7F25_00460	COG2814	Major facilitator Superfamily
H7F25_00465	COG1309	transcriptional regulator
H7F25_00475	COG0640	Transcriptional regulator
H7F25_00480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F25_00485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F25_00490	COG0531	amino acid
H7F25_00495	COG1012	belongs to the aldehyde dehydrogenase family
H7F25_00500	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F25_00505	COG4549	nuclear export factor GLE1
H7F25_00510	COG2372	response to copper ion
H7F25_00510	COG1276	copper resistance
H7F25_00515	COG2213	PTS system mannitol-specific
H7F25_00520	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F25_00525	COG0246	Mannitol dehydrogenase
H7F25_00530	COG0840	transmembrane signaling receptor activity
H7F25_00555	COG0346	lactoylglutathione lyase activity
H7F25_00565	COG0561	phosphatase activity
H7F25_00570	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F25_00575	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F25_00580	COG4336	lyase activity
H7F25_00585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7F25_00590	COG1984	allophanate hydrolase subunit 2
H7F25_00595	COG1414	Transcriptional regulator
H7F25_00600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F25_00605	COG2755	lipolytic protein G-D-S-L family
H7F25_00615	COG3711	transcriptional antiterminator
H7F25_00620	COG2226	methyltransferase
H7F25_00625	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_00630	COG3871	stress protein (general stress protein 26)
H7F25_00655	COG2814	Major facilitator Superfamily
H7F25_00660	COG1802	Transcriptional regulator
H7F25_00665	COG1917	Cupin 2, conserved barrel domain protein
H7F25_00665	COG2207	Transcriptional regulator
H7F25_00670	COG0697	spore germination
H7F25_00675	COG0473	3-isopropylmalate dehydrogenase activity
H7F25_00680	COG0551	DNA topoisomerase type I activity
H7F25_00680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F25_00685	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H7F25_00690	COG3706	GGDEF domain
H7F25_00695	COG5298	Protein conserved in bacteria
H7F25_00700	COG1215	transferase activity, transferring glycosyl groups
H7F25_00710	COG0531	amino acid
H7F25_00715	COG0028	Belongs to the TPP enzyme family
H7F25_00720	COG5444	nuclease activity
H7F25_00745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F25_00750	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F25_00755	COG2261	transglycosylase associated protein
H7F25_00760	COG2217	Heavy metal translocating P-type atpase
H7F25_00765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F25_00770	COG3290	protein histidine kinase activity
H7F25_00775	COG4565	transcriptional regulatory protein
H7F25_00780	COG1301	dicarboxylic acid transport
H7F25_00785	COG0628	permease
H7F25_00790	COG1301	dicarboxylic acid transport
H7F25_00795	COG1131	(ABC) transporter
H7F25_00800	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F25_00815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F25_00820	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7F25_00825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7F25_00840	COG0513	Belongs to the DEAD box helicase family
H7F25_00845	COG3402	PFAM membrane-flanked domain
H7F25_00850	COG3428	Bacterial PH domain
H7F25_00855	COG0705	Rhomboid family
H7F25_00860	COG0736	holo-[acyl-carrier-protein] synthase activity
H7F25_00865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7F25_00870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F25_00875	COG0864	Transcriptional regulator
H7F25_00880	COG2337	Toxic component of a toxin-antitoxin (TA) module
H7F25_00885	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F25_00890	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F25_00895	COG2172	sigma factor antagonist activity
H7F25_00900	COG2208	phosphoserine phosphatase activity
H7F25_00905	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F25_00910	COG2172	sigma factor antagonist activity
H7F25_00915	COG1191	sigma factor activity
H7F25_00920	COG2208	phosphoserine phosphatase activity
H7F25_00925	COG2183	response to ionizing radiation
H7F25_00935	COG3091	SprT-like family
H7F25_00940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F25_00945	COG0022	dehydrogenase e1 component
H7F25_00950	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F25_00955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F25_00960	COG3284	Transcriptional regulator
H7F25_01000	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H7F25_01010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F25_01015	COG0456	acetyltransferase
H7F25_01015	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H7F25_01020	COG1278	Cold shock
H7F25_01025	COG1404	Belongs to the peptidase S8 family
H7F25_01040	COG0789	Transcriptional regulator
H7F25_01050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F25_01075	COG0477	Major facilitator Superfamily
H7F25_01080	COG0657	acetylesterase activity
H7F25_01085	COG4221	oxidoreductase activity
H7F25_01095	COG0252	asparaginase activity
H7F25_01115	COG2814	Major facilitator Superfamily
H7F25_01120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F25_01150	COG1309	transcriptional regulator
H7F25_01155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7F25_01160	COG1846	Transcriptional regulator
H7F25_01165	COG0778	Nitroreductase
H7F25_01180	COG1396	sequence-specific DNA binding
H7F25_01200	COG4122	O-methyltransferase activity
H7F25_01210	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H7F25_01215	COG0697	spore germination
H7F25_01225	COG1301	dicarboxylic acid transport
H7F25_01265	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H7F25_01270	COG0802	atpase or kinase
H7F25_01275	COG1214	PFAM Peptidase M22, glycoprotease
H7F25_01280	COG0456	acetyltransferase
H7F25_01285	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H7F25_01290	COG0488	(ABC) transporter
H7F25_01295	COG0315	cyclic pyranopterin monophosphate synthase activity
H7F25_01300	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
H7F25_01305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F25_01310	COG0805	protein transport
H7F25_01325	COG1266	CAAX protease self-immunity
H7F25_01330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H7F25_01335	COG0459	protein refolding
H7F25_01410	COG1846	Transcriptional regulator
H7F25_01415	COG0456	acetyltransferase
H7F25_01420	COG2808	Putative FMN-binding domain
H7F25_01450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7F25_01455	COG0823	Involved in the tonB-independent uptake of proteins
H7F25_01465	COG2132	Multicopper oxidase
H7F25_01470	COG1113	amino acid transport
H7F25_01475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F25_01480	COG0714	Associated with various cellular activities
H7F25_01485	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
H7F25_01490	COG1305	Transglutaminase-like
H7F25_01495	COG0519	Catalyzes the synthesis of GMP from XMP
H7F25_01495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7F25_01500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7F25_01510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F25_01515	COG2207	Transcriptional regulator
H7F25_01530	COG1404	Belongs to the peptidase S8 family
H7F25_01545	COG2814	Major facilitator Superfamily
H7F25_01550	COG0583	DNA-binding transcription factor activity
H7F25_01555	COG2252	PERMEase
H7F25_01570	COG3064	Membrane
H7F25_01575	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
H7F25_01585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H7F25_01590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7F25_01595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7F25_01600	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H7F25_01605	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F25_01610	COG0047	phosphoribosylformylglycinamidine synthase activity
H7F25_01615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F25_01620	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H7F25_01625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H7F25_01630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7F25_01635	COG0138	bifunctional purine biosynthesis protein purh
H7F25_01640	COG0151	Belongs to the GarS family
H7F25_01660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F25_01665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7F25_01670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7F25_01675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F25_01685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7F25_01690	COG4496	protein, YerC YecD
H7F25_01695	COG0069	glutamate synthase activity
H7F25_01710	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
H7F25_01715	COG0210	DNA helicase
H7F25_01720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H7F25_01725	COG4851	CamS sex pheromone cAM373 precursor
H7F25_01740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F25_01755	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F25_01770	COG1960	acyl-CoA dehydrogenase activity
H7F25_01800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F25_01805	COG1785	Belongs to the alkaline phosphatase family
H7F25_01810	COG1285	pathogenesis
H7F25_01815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F25_01820	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F25_01825	COG0154	amidase activity
H7F25_01830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F25_01835	COG1309	transcriptional regulator
H7F25_01840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F25_01845	COG1957	nucleoside hydrolase
H7F25_01850	COG1597	lipid kinase activity
H7F25_01855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F25_01860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F25_01870	COG1737	Transcriptional regulator
H7F25_01875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F25_01875	COG1263	PTS System
H7F25_01880	COG1486	melibiose metabolic process
H7F25_01890	COG1959	2 iron, 2 sulfur cluster binding
H7F25_01895	COG0492	ferredoxin-NADP+ reductase activity
H7F25_01910	COG1486	melibiose metabolic process
H7F25_01920	COG2211	Major facilitator Superfamily
H7F25_01950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H7F25_01955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F25_01960	COG1442	glycosyl transferase family 8
H7F25_01965	COG1216	Glycosyl transferase, family 2
H7F25_01970	COG1442	glycosyl transferase family 8
H7F25_01975	COG2223	nitrite transmembrane transporter activity
H7F25_01985	COG0471	metal ion transport
H7F25_02000	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F25_02015	COG0531	amino acid
H7F25_02020	COG0463	Glycosyl transferase, family 2
H7F25_02025	COG0488	(ABC) transporter
H7F25_02030	COG1469	GTP cyclohydrolase I activity
H7F25_02035	COG0789	Transcriptional regulator
H7F25_02040	COG2814	Major facilitator Superfamily
H7F25_02045	COG0488	(ABC) transporter
H7F25_02050	COG0513	Belongs to the DEAD box helicase family
H7F25_02065	COG2130	NADP-dependent
H7F25_02085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F25_02085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F25_02090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7F25_02100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F25_02100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F25_02110	COG3290	protein histidine kinase activity
H7F25_02115	COG4565	transcriptional regulatory protein
H7F25_02120	COG3181	Tripartite tricarboxylate transporter family receptor
H7F25_02125	COG2851	Citrate transporter
H7F25_02135	COG3479	Phenolic acid decarboxylase
H7F25_02140	COG1695	Transcriptional regulator
H7F25_02145	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
H7F25_02150	COG1254	Belongs to the acylphosphatase family
H7F25_02155	COG2258	MOSC domain
H7F25_02170	COG0024	Methionine aminopeptidase
H7F25_02175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F25_02175	COG1263	PTS System
H7F25_02180	COG3739	integral membrane protein
H7F25_02195	COG1368	sulfuric ester hydrolase activity
H7F25_02200	COG0076	glutamate decarboxylase activity
H7F25_02205	COG0840	transmembrane signaling receptor activity
H7F25_02215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F25_02215	COG1263	PTS System
H7F25_02220	COG0366	Alpha amylase catalytic
H7F25_02225	COG2188	Transcriptional regulator
H7F25_02235	COG0737	Belongs to the 5'-nucleotidase family
H7F25_02240	COG0693	protein deglycase activity
H7F25_02245	COG4840	Belongs to the UPF0435 family
H7F25_02250	COG1115	amino acid carrier protein
H7F25_02255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F25_02260	COG4980	gas vesicle protein
H7F25_02265	COG1295	ribonuclease BN
H7F25_02270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F25_02285	COG0387	Pfam Sodium calcium exchanger
H7F25_02295	COG0217	transcriptional regulatory protein
H7F25_02300	COG0668	transmembrane transport
H7F25_02305	COG0535	radical SAM domain protein
H7F25_02315	COG0726	polysaccharide deacetylase
H7F25_02320	COG0598	Magnesium transport protein CorA
H7F25_02330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H7F25_02335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F25_02350	COG0789	Transcriptional regulator
H7F25_02355	COG2814	Major facilitator Superfamily
H7F25_02365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F25_02410	COG2076	Multidrug Resistance protein
H7F25_02415	COG2076	Multidrug Resistance protein
H7F25_02420	COG1309	transcriptional regulator
H7F25_02430	COG4637	Psort location Cytoplasmic, score
H7F25_02435	COG2755	lipolytic protein G-D-S-L family
H7F25_02440	COG0492	ferredoxin-NADP+ reductase activity
H7F25_02445	COG1742	UPF0060 membrane protein
H7F25_02460	COG2318	DinB family
H7F25_02470	COG1846	Transcriptional regulator
H7F25_02475	COG0392	lysyltransferase activity
H7F25_02475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H7F25_02495	COG0778	Nitroreductase
H7F25_02510	COG1090	epimerase
H7F25_02515	COG2137	regulation of response to DNA damage stimulus
H7F25_02540	COG0463	Glycosyl transferase, family 2
H7F25_02545	COG4485	Bacterial membrane protein, YfhO
H7F25_02555	COG2140	Oxalate decarboxylase
H7F25_02565	COG1191	sigma factor activity
H7F25_02575	COG1988	membrane-bound metal-dependent
H7F25_02580	COG1194	a g-specific adenine glycosylase
H7F25_02590	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_02605	COG3557	Belongs to the UPF0374 family
H7F25_02610	COG1132	(ABC) transporter
H7F25_02615	COG0444	Belongs to the ABC transporter superfamily
H7F25_02620	COG4608	Belongs to the ABC transporter superfamily
H7F25_02625	COG0747	negative chemotaxis
H7F25_02630	COG0601	transmembrane transport
H7F25_02635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F25_02640	COG4129	membrane
H7F25_02645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F25_02650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7F25_02655	COG0735	belongs to the Fur family
H7F25_02805	COG1368	sulfuric ester hydrolase activity
H7F25_02810	COG0681	Belongs to the peptidase S26 family
H7F25_02815	COG2873	o-acetylhomoserine
H7F25_02825	COG1116	anion transmembrane transporter activity
H7F25_02830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F25_02835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F25_02850	COG4152	abc transporter atp-binding protein
H7F25_02880	COG3382	B3 4 domain protein
H7F25_02885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7F25_02895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7F25_02900	COG2766	serine protein kinase
H7F25_02905	COG2718	Belongs to the UPF0229 family
H7F25_02910	COG1566	PFAM secretion protein HlyD family protein
H7F25_02915	COG2814	Major facilitator Superfamily
H7F25_02920	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7F25_02930	COG1278	Cold shock
H7F25_02935	COG3706	GGDEF domain
H7F25_02960	COG5577	PFAM Coat F domain
H7F25_02965	COG5002	protein histidine kinase activity
H7F25_02970	COG4085	toxin activity
H7F25_02970	COG1525	nuclease
H7F25_02970	COG0737	Belongs to the 5'-nucleotidase family
H7F25_02975	COG3764	Sortase (surface protein transpeptidase)
H7F25_02980	COG0564	pseudouridine synthase activity
H7F25_02990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F25_02995	COG3153	acetyltransferase
H7F25_02995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F25_03010	COG3835	regulator
H7F25_03015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F25_03020	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H7F25_03025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7F25_03030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7F25_03035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H7F25_03040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F25_03045	COG2203	Gaf domain
H7F25_03045	COG4585	Histidine kinase
H7F25_03050	COG2197	response regulator
H7F25_03065	COG0753	catalase activity
H7F25_03070	COG1959	2 iron, 2 sulfur cluster binding
H7F25_03075	COG1017	nitric oxide dioxygenase activity
H7F25_03075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7F25_03080	COG2719	SpoVR family
H7F25_03085	COG1785	Belongs to the alkaline phosphatase family
H7F25_03090	COG1388	LysM domain
H7F25_03090	COG0791	NLP P60 protein
H7F25_03095	COG0531	amino acid
H7F25_03110	COG1595	DNA-templated transcription, initiation
H7F25_03115	COG0204	Acyl-transferase
H7F25_03120	COG1253	flavin adenine dinucleotide binding
H7F25_03125	COG0789	Transcriptional regulator
H7F25_03130	COG1253	flavin adenine dinucleotide binding
H7F25_03140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F25_03145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F25_03150	COG0584	glycerophosphoryl diester phosphodiesterase
H7F25_03160	COG0668	transmembrane transport
H7F25_03165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H7F25_03170	COG0726	polysaccharide deacetylase
H7F25_03175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F25_03180	COG0589	response to stress
H7F25_03185	COG1132	(ABC) transporter
H7F25_03190	COG1132	(ABC) transporter
H7F25_03200	COG0702	epimerase
H7F25_03210	COG3842	ATPase activity
H7F25_03215	COG2508	Transcriptional regulator
H7F25_03225	COG0189	ligase activity
H7F25_03230	COG0189	ligase activity
H7F25_03235	COG4399	Belongs to the UPF0754 family
H7F25_03240	COG3679	Belongs to the UPF0342 family
H7F25_03245	COG0561	phosphatase activity
H7F25_03250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F25_03260	COG0475	glutathione-regulated potassium exporter activity
H7F25_03265	COG0490	domain, Protein
H7F25_03275	COG1024	Enoyl-CoA hydratase
H7F25_03285	COG0420	3'-5' exonuclease activity
H7F25_03290	COG4717	serine-type aminopeptidase activity
H7F25_03295	COG3481	metal-dependent phosphohydrolase, HD sub domain
H7F25_03305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F25_03330	COG1846	Transcriptional regulator
H7F25_03335	COG4980	gas vesicle protein
H7F25_03350	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H7F25_03355	COG0537	adenosine 5'-monophosphoramidase activity
H7F25_03360	COG1131	(ABC) transporter
H7F25_03365	COG4473	ABC transporter
H7F25_03375	COG1473	amidohydrolase
H7F25_03385	COG2329	Antibiotic biosynthesis monooxygenase
H7F25_03390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F25_03395	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H7F25_03400	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H7F25_03405	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H7F25_03410	COG1309	transcriptional regulator
H7F25_03415	COG1511	domain protein
H7F25_03420	COG1363	Peptidase, m42
H7F25_03425	COG1301	dicarboxylic acid transport
H7F25_03435	COG1234	tRNA 3'-trailer cleavage
H7F25_03440	COG0095	Lipoate-protein ligase
H7F25_03445	COG0318	PFAM AMP-dependent synthetase and ligase
H7F25_03455	COG0501	Belongs to the peptidase M48B family
H7F25_03460	COG1404	Belongs to the peptidase S8 family
H7F25_03465	COG0406	alpha-ribazole phosphatase activity
H7F25_03470	COG0840	transmembrane signaling receptor activity
H7F25_03475	COG0723	plastoquinol--plastocyanin reductase activity
H7F25_03475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F25_03480	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_03490	COG4903	ComK protein
H7F25_03500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F25_03505	COG2814	Major facilitator Superfamily
H7F25_03510	COG2732	(Barnase) inhibitor
H7F25_03515	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F25_03520	COG4605	iron ion homeostasis
H7F25_03525	COG4604	ABC transporter, ATP-binding protein
H7F25_03530	COG4607	ABC-type enterochelin transport system periplasmic component
H7F25_03535	COG1316	TRANSCRIPTIONal
H7F25_03545	COG0398	Pfam SNARE associated Golgi protein
H7F25_03550	COG0681	Belongs to the peptidase S26 family
H7F25_03555	COG3180	Ammonia monooxygenase
H7F25_03565	COG0501	Belongs to the peptidase M48B family
H7F25_03570	COG2259	Doxx family
H7F25_03575	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
H7F25_03580	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H7F25_03585	COG1074	ATP-dependent DNA helicase activity
H7F25_03590	COG0420	3'-5' exonuclease activity
H7F25_03595	COG0419	ATPase involved in DNA repair
H7F25_03600	COG1403	HNH endonuclease
H7F25_03640	COG5337	Spore coat protein CotH
H7F25_03650	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F25_03665	COG0367	asparagine synthase
H7F25_03680	COG1562	ergosterol biosynthetic process
H7F25_03685	COG0534	Mate efflux family protein
H7F25_03690	COG2207	Transcriptional regulator
H7F25_03690	COG1917	Cupin 2, conserved barrel domain protein
H7F25_03720	COG0076	glutamate decarboxylase activity
H7F25_03750	COG0646	methionine synthase
H7F25_03750	COG1410	methionine synthase
H7F25_03755	COG0646	methionine synthase
H7F25_03755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H7F25_03760	COG1666	GTP binding
H7F25_03765	COG2996	Protein conserved in bacteria
H7F25_03770	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F25_03775	COG0840	transmembrane signaling receptor activity
H7F25_03780	COG1307	EDD domain protein, DegV family
H7F25_03785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F25_03805	COG0561	phosphatase activity
H7F25_03810	COG1073	alpha beta
H7F25_03815	COG2151	metal-sulfur cluster biosynthetic enzyme
H7F25_03820	COG0277	FAD linked oxidase domain protein
H7F25_03825	COG2271	Major facilitator Superfamily
H7F25_03830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H7F25_03835	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H7F25_03840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7F25_03845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F25_03850	COG0505	Belongs to the CarA family
H7F25_03855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F25_03860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7F25_03870	COG2814	Major facilitator Superfamily
H7F25_03880	COG2267	carboxylic ester hydrolase activity
H7F25_03890	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F25_03905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F25_03910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F25_03915	COG5504	Zn-dependent protease
H7F25_03920	COG0444	Belongs to the ABC transporter superfamily
H7F25_03925	COG4608	Belongs to the ABC transporter superfamily
H7F25_03935	COG0601	transmembrane transport
H7F25_03940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F25_03960	COG0180	Tryptophanyl-tRNA synthetase
H7F25_03970	COG4166	transmembrane transport
H7F25_03975	COG0601	transmembrane transport
H7F25_03980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F25_03985	COG0444	Belongs to the ABC transporter superfamily
H7F25_03990	COG4608	Belongs to the ABC transporter superfamily
H7F25_04000	COG0456	acetyltransferase
H7F25_04005	COG1393	Belongs to the ArsC family
H7F25_04010	COG0861	Integral membrane protein TerC family
H7F25_04015	COG4862	establishment of competence for transformation
H7F25_04020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F25_04030	COG1164	Oligoendopeptidase f
H7F25_04040	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7F25_04045	COG2346	COG2346, Truncated hemoglobins
H7F25_04050	COG0741	lytic transglycosylase activity
H7F25_04055	COG4116	CYTH
H7F25_04065	COG2357	RelA SpoT domain protein
H7F25_04070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F25_04075	COG0564	pseudouridine synthase activity
H7F25_04080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7F25_04085	COG0569	domain protein
H7F25_04085	COG0475	glutathione-regulated potassium exporter activity
H7F25_04090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7F25_04095	COG0352	thiamine-phosphate diphosphorylase activity
H7F25_04105	COG2104	thiamine diphosphate biosynthetic process
H7F25_04110	COG2022	thiamine diphosphate biosynthetic process
H7F25_04115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F25_04120	COG0351	phosphomethylpyrimidine kinase
H7F25_04125	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H7F25_04180	COG0210	DNA helicase
H7F25_04195	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7F25_04200	COG2382	esterase
H7F25_04205	COG0626	cystathionine gamma-synthase activity
H7F25_04210	COG0626	cystathionine gamma-synthase activity
H7F25_04360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H7F25_04390	COG1780	Probably involved in ribonucleotide reductase function
H7F25_04395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F25_04405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F25_04425	COG0756	dUTP diphosphatase activity
H7F25_04435	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
H7F25_04520	COG0582	viral genome integration into host DNA
H7F25_04595	COG1705	Flagellar rod assembly protein muramidase FlgJ
H7F25_04630	COG5632	N-Acetylmuramoyl-L-alanine amidase
H7F25_04630	COG3409	Peptidoglycan-binding domain 1 protein
H7F25_04665	COG0457	Tetratricopeptide repeat
H7F25_04670	COG1733	regulation of RNA biosynthetic process
H7F25_04680	COG0604	alcohol dehydrogenase
H7F25_04690	COG0825	malonyl-CoA metabolic process
H7F25_04700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F25_04750	COG0457	Tetratricopeptide repeat
H7F25_04780	COG0583	DNA-binding transcription factor activity
H7F25_04785	COG2807	transmembrane transport
H7F25_04805	COG0457	Tetratricopeptide repeat
H7F25_04835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F25_04855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F25_04860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F25_04865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F25_04885	COG4195	phage-related replication protein
H7F25_04890	COG2856	Zn peptidase
H7F25_04895	COG5632	N-Acetylmuramoyl-L-alanine amidase
H7F25_04895	COG3409	Peptidoglycan-binding domain 1 protein
H7F25_04915	COG0306	phosphate transporter
H7F25_04920	COG1392	Phosphate transport regulator
H7F25_04930	COG0405	Gamma-glutamyltransferase
H7F25_04935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H7F25_04945	COG4208	sulfate ABC transporter
H7F25_04950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H7F25_04960	COG3775	system Galactitol-specific IIC component
H7F25_04975	COG1063	alcohol dehydrogenase
H7F25_04980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F25_04985	COG0022	dehydrogenase e1 component
H7F25_04985	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F25_04990	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F25_04995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F25_05000	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_05005	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_05010	COG2390	Transcriptional regulator
H7F25_05020	COG0531	amino acid
H7F25_05025	COG0346	lactoylglutathione lyase activity
H7F25_05030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F25_05035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F25_05040	COG2362	D-Aminopeptidase
H7F25_05045	COG0601	transmembrane transport
H7F25_05050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F25_05055	COG0444	Belongs to the ABC transporter superfamily
H7F25_05060	COG4166	transmembrane transport
H7F25_05065	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F25_05070	COG4948	Mandelate Racemase Muconate Lactonizing
H7F25_05075	COG0791	NLP P60 protein
H7F25_05080	COG4608	Belongs to the ABC transporter superfamily
H7F25_05085	COG1834	amidinotransferase
H7F25_05090	COG1607	acyl-coa hydrolase
H7F25_05095	COG1695	Transcriptional regulator
H7F25_05110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F25_05125	COG2076	Multidrug Resistance protein
H7F25_05130	COG2076	Multidrug Resistance protein
H7F25_05140	COG0788	formyltetrahydrofolate deformylase activity
H7F25_05145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F25_05150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F25_05155	COG0457	Tetratricopeptide repeat
H7F25_05165	COG1764	response to oxidative stress
H7F25_05170	COG1846	Transcriptional regulator
H7F25_05175	COG1764	response to oxidative stress
H7F25_05180	COG0590	tRNA wobble adenosine to inosine editing
H7F25_05185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F25_05190	COG1404	Belongs to the peptidase S8 family
H7F25_05195	COG0745	RESPONSE REGULATOR receiver
H7F25_05200	COG5002	protein histidine kinase activity
H7F25_05200	COG3850	Histidine kinase
H7F25_05205	COG3212	peptidase
H7F25_05210	COG3212	peptidase
H7F25_05220	COG2239	Acts as a magnesium transporter
H7F25_05230	COG0789	Transcriptional regulator
H7F25_05250	COG1846	Transcriptional regulator
H7F25_05255	COG3300	MHYT domain
H7F25_05255	COG5001	Diguanylate cyclase
H7F25_05260	COG0586	Pfam SNARE associated Golgi protein
H7F25_05265	COG0861	Integral membrane protein TerC family
H7F25_05270	COG1191	sigma factor activity
H7F25_05290	COG0501	Belongs to the peptidase M48B family
H7F25_05295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7F25_05300	COG2323	membrane
H7F25_05315	COG3594	Acyltransferase
H7F25_05320	COG5002	protein histidine kinase activity
H7F25_05325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7F25_05335	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H7F25_05340	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
H7F25_05345	COG0436	Aminotransferase
H7F25_05350	COG1850	ribulose-bisphosphate carboxylase activity
H7F25_05360	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H7F25_05370	COG3852	Histidine kinase
H7F25_05375	COG1846	Transcriptional regulator
H7F25_05380	COG1360	Flagellar Motor Protein
H7F25_05385	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7F25_05390	COG0542	response to heat
H7F25_05395	COG3949	Membrane
H7F25_05400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7F25_05405	COG0720	synthase
H7F25_05410	COG0602	queuosine metabolic process
H7F25_05415	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7F25_05420	COG1733	regulation of RNA biosynthetic process
H7F25_05425	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_05435	COG4873	Protein conserved in bacteria
H7F25_05445	COG3773	Cell wall hydrolase
H7F25_05450	COG2244	polysaccharide biosynthetic process
H7F25_05455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F25_05460	COG2217	Heavy metal translocating P-type atpase
H7F25_05465	COG0006	proline dipeptidase activity
H7F25_05475	COG1609	Transcriptional regulator
H7F25_05480	COG3711	transcriptional antiterminator
H7F25_05485	COG1263	PTS System
H7F25_05485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F25_05485	COG2190	(PTS) system
H7F25_05490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F25_05495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7F25_05505	COG1533	DNA photolyase activity
H7F25_05510	COG0840	transmembrane signaling receptor activity
H7F25_05520	COG2084	Dehydrogenase
H7F25_05525	COG2340	Cysteine-rich secretory protein family
H7F25_05530	COG0768	penicillin binding
H7F25_05535	COG4191	Histidine kinase
H7F25_05540	COG0436	Aminotransferase
H7F25_05545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F25_05555	COG1714	RDD family
H7F25_05565	COG0835	chemotaxis
H7F25_05565	COG0784	Response regulator, receiver
H7F25_05575	COG2207	Transcriptional regulator
H7F25_05575	COG1917	Cupin 2, conserved barrel domain protein
H7F25_05580	COG0697	spore germination
H7F25_05590	COG2814	Major facilitator Superfamily
H7F25_05595	COG1376	ErfK ybiS ycfS ynhG family protein
H7F25_05600	COG1408	metallophosphoesterase
H7F25_05605	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_05610	COG2200	EAL domain
H7F25_05615	COG3546	catalase activity
H7F25_05620	COG4703	Protein of unknown function (DUF1797)
H7F25_05625	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
H7F25_05635	COG0517	IMP dehydrogenase activity
H7F25_05640	COG0583	DNA-binding transcription factor activity
H7F25_05645	COG0716	FMN binding
H7F25_05655	COG0716	FMN binding
H7F25_05660	COG2171	N-acyltransferase activity
H7F25_05665	COG1473	amidohydrolase
H7F25_05675	COG0668	transmembrane transport
H7F25_05680	COG0450	alkyl hydroperoxide reductase
H7F25_05685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F25_05700	COG0746	molybdenum cofactor guanylyltransferase activity
H7F25_05705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F25_05710	COG0303	'Molybdopterin
H7F25_05715	COG1763	Mo-molybdopterin cofactor biosynthetic process
H7F25_05720	COG0314	molybdopterin synthase activity
H7F25_05725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H7F25_05740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F25_05745	COG1136	(ABC) transporter
H7F25_05750	COG0577	efflux transmembrane transporter activity
H7F25_05755	COG1349	DNA-binding transcription factor activity
H7F25_05760	COG1105	Belongs to the carbohydrate kinase PfkB family
H7F25_05765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F25_05765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F25_05765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F25_05770	COG0681	Belongs to the peptidase S26 family
H7F25_05780	COG0488	(ABC) transporter
H7F25_05785	COG2309	aminopeptidase activity
H7F25_05795	COG1077	Cell shape determining protein MreB Mrl
H7F25_05800	COG2002	toxin-antitoxin pair type II binding
H7F25_05805	COG3852	Histidine kinase
H7F25_05810	COG2105	PFAM AIG2 family protein
H7F25_05810	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H7F25_05815	COG0569	domain protein
H7F25_05820	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7F25_05825	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H7F25_05830	COG5503	Protein of unknown function (DUF1447)
H7F25_05835	COG0561	phosphatase activity
H7F25_05840	COG0242	peptide deformylase activity
H7F25_05855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F25_05860	COG0022	dehydrogenase e1 component
H7F25_05865	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F25_05870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F25_05875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F25_05885	COG1982	Orn Lys Arg decarboxylase major
H7F25_05890	COG4476	Belongs to the UPF0223 family
H7F25_05895	COG4493	Belongs to the UPF0637 family
H7F25_05905	COG0483	inositol monophosphate 1-phosphatase activity
H7F25_05920	COG1595	DNA-templated transcription, initiation
H7F25_05940	COG1217	gtp-binding protein TYPA
H7F25_05950	COG4896	Protein conserved in bacteria
H7F25_05960	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H7F25_05965	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F25_05970	COG2066	Belongs to the glutaminase family
H7F25_05975	COG4838	Belongs to the UPF0358 family
H7F25_05980	COG0772	Belongs to the SEDS family
H7F25_05985	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H7F25_05990	COG0415	Belongs to the DNA photolyase family
H7F25_05995	COG1612	heme a metabolic process
H7F25_06000	COG0109	protoheme IX farnesyltransferase activity
H7F25_06005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F25_06005	COG2010	Cytochrome c
H7F25_06010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F25_06015	COG1845	cytochrome c oxidase, subunit III
H7F25_06020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F25_06025	COG3336	cytochrome c oxidase
H7F25_06035	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H7F25_06040	COG2340	Cysteine-rich secretory protein family
H7F25_06060	COG3679	Belongs to the UPF0342 family
H7F25_06065	COG4471	UPF0298 protein
H7F25_06070	COG0742	ribosomal rna small subunit methyltransferase
H7F25_06075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H7F25_06080	COG3314	Sporulation integral membrane protein YlbJ
H7F25_06085	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7F25_06090	COG3480	Lon protease (S16) C-terminal proteolytic domain
H7F25_06100	COG1399	metal-binding, possibly nucleic acid-binding protein
H7F25_06105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H7F25_06115	COG0454	-acetyltransferase
H7F25_06120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F25_06125	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
H7F25_06130	COG2001	Belongs to the MraZ family
H7F25_06135	COG0275	rRNA processing
H7F25_06140	COG4839	cell division protein FtsL
H7F25_06145	COG0768	penicillin binding
H7F25_06150	COG0768	penicillin binding
H7F25_06155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F25_06160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F25_06165	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F25_06170	COG0772	Belongs to the SEDS family
H7F25_06175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F25_06180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H7F25_06185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7F25_06190	COG3879	Bacterial protein of unknown function (DUF881)
H7F25_06195	COG3879	Bacterial protein of unknown function (DUF881)
H7F25_06200	COG3856	small basic protein
H7F25_06205	COG0849	cell division
H7F25_06210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7F25_06215	COG4412	M6 family metalloprotease domain protein
H7F25_06215	COG1404	Belongs to the peptidase S8 family
H7F25_06225	COG1191	sigma factor activity
H7F25_06230	COG1191	sigma factor activity
H7F25_06235	COG2390	Transcriptional regulator
H7F25_06250	COG3730	PTS system glucitol sorbitol-specific
H7F25_06255	COG3732	PTS system glucitol sorbitol-specific
H7F25_06265	COG1119	ATPase activity
H7F25_06270	COG1873	PFAM PRC-barrel domain
H7F25_06275	COG1496	oxidoreductase activity
H7F25_06280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H7F25_06285	COG1799	cell septum assembly
H7F25_06290	COG0762	integral membrane protein
H7F25_06295	COG2302	S4 RNA-binding domain
H7F25_06300	COG3599	regulation of cell shape
H7F25_06305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H7F25_06310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F25_06315	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H7F25_06320	COG0564	pseudouridine synthase activity
H7F25_06325	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H7F25_06330	COG2233	PERMEase
H7F25_06335	COG0540	Belongs to the ATCase OTCase family
H7F25_06340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H7F25_06345	COG0505	Belongs to the CarA family
H7F25_06350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F25_06355	COG0543	2 iron, 2 sulfur cluster binding
H7F25_06360	COG0167	dihydroorotate dehydrogenase activity
H7F25_06365	COG0284	orotidine-5'-phosphate decarboxylase activity
H7F25_06370	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H7F25_06380	COG0175	sulfate reduction
H7F25_06385	COG0306	phosphate transporter
H7F25_06390	COG2046	Belongs to the sulfate adenylyltransferase family
H7F25_06395	COG0529	Catalyzes the synthesis of activated sulfate
H7F25_06400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7F25_06405	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
H7F25_06410	COG1648	precorrin-2 dehydrogenase activity
H7F25_06420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7F25_06425	COG1561	YicC-like family, N-terminal region
H7F25_06430	COG2052	Domain of unknown function (DUF370)
H7F25_06435	COG0194	GDP metabolic process
H7F25_06440	COG1758	RNA polymerase activity
H7F25_06445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F25_06450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7F25_06455	COG0242	peptide deformylase activity
H7F25_06460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H7F25_06465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F25_06465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7F25_06470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H7F25_06475	COG0631	protein serine/threonine phosphatase activity
H7F25_06480	COG2815	serine threonine protein kinase
H7F25_06480	COG0515	serine threonine protein kinase
H7F25_06485	COG1162	GTPase activity
H7F25_06490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7F25_06495	COG1564	THIamine pyrophosphokinase
H7F25_06505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H7F25_06510	COG1302	Protein conserved in bacteria
H7F25_06515	COG1461	Dihydroxyacetone kinase
H7F25_06520	COG1760	l-serine dehydratase
H7F25_06525	COG1760	l-serine dehydratase
H7F25_06530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7F25_06535	COG1349	DNA-binding transcription factor activity
H7F25_06540	COG0416	fatty acid biosynthetic process
H7F25_06545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7F25_06550	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_06555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F25_06565	COG1196	nuclear chromosome segregation
H7F25_06570	COG0552	protein localization to endoplasmic reticulum
H7F25_06575	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H7F25_06580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7F25_06585	COG0228	four-way junction DNA binding
H7F25_06590	COG1837	Belongs to the UPF0109 family
H7F25_06600	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7F25_06605	COG0336	Belongs to the RNA methyltransferase TrmD family
H7F25_06610	COG0335	large ribosomal subunit rRNA binding
H7F25_06615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F25_06620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F25_06630	COG2257	FlhB HrpN YscU SpaS Family
H7F25_06635	COG0045	succinate-CoA ligase (ADP-forming) activity
H7F25_06640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F25_06645	COG0758	DNA mediated transformation
H7F25_06650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F25_06655	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H7F25_06660	COG4974	Belongs to the 'phage' integrase family
H7F25_06665	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H7F25_06670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H7F25_06675	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7F25_06680	COG1815	bacterial-type flagellum-dependent cell motility
H7F25_06685	COG1558	bacterial-type flagellum-dependent cell motility
H7F25_06690	COG1677	Flagellar hook-basal body complex protein FliE
H7F25_06695	COG1766	The M ring may be actively involved in energy transduction
H7F25_06700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F25_06705	COG1317	bacterial-type flagellum organization
H7F25_06710	COG1157	protein secretion by the type III secretion system
H7F25_06715	COG2882	bacterial-type flagellum organization
H7F25_06720	COG3334	PFAM MgtE intracellular
H7F25_06725	COG3144	bacterial-type flagellum assembly
H7F25_06730	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H7F25_06735	COG4786	Flagellar basal body rod
H7F25_06740	COG1582	Flagellar protein (FlbD)
H7F25_06745	COG1580	Controls the rotational direction of flagella during chemotaxis
H7F25_06750	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F25_06755	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F25_06755	COG1776	CheC inhibitor of MCP methylation
H7F25_06760	COG2201	protein-glutamate methylesterase activity
H7F25_06765	COG3190	flagellar
H7F25_06770	COG1338	Plays a role in the flagellum-specific transport system
H7F25_06775	COG1987	bacterial-type flagellum assembly
H7F25_06780	COG1684	flagellar biosynthetic protein fliR
H7F25_06785	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F25_06790	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F25_06795	COG1419	protein localization to endoplasmic reticulum
H7F25_06800	COG0455	bacterial-type flagellum organization
H7F25_06805	COG2201	protein-glutamate methylesterase activity
H7F25_06810	COG2198	Histidine kinase
H7F25_06810	COG0643	Histidine kinase
H7F25_06815	COG0835	chemotaxis
H7F25_06820	COG1776	CheC inhibitor of MCP methylation
H7F25_06830	COG1191	sigma factor activity
H7F25_06845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H7F25_06850	COG0528	UMP kinase activity
H7F25_06855	COG0233	cytoplasmic translational termination
H7F25_06860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7F25_06865	COG4589	Belongs to the CDS family
H7F25_06870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H7F25_06875	COG0750	zinc metalloprotease
H7F25_06880	COG0442	prolyl-tRNA aminoacylation
H7F25_06885	COG2176	DNA-directed DNA polymerase activity
H7F25_06900	COG3693	PFAM glycoside hydrolase, family 10
H7F25_06910	COG0779	Required for maturation of 30S ribosomal subunits
H7F25_06915	COG0195	Participates in both transcription termination and antitermination
H7F25_06920	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H7F25_06925	COG1358	cellular component organization or biogenesis
H7F25_06930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H7F25_06935	COG1550	Protein conserved in bacteria
H7F25_06940	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H7F25_06945	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7F25_06950	COG0196	riboflavin kinase activity
H7F25_06955	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H7F25_06960	COG1185	polyribonucleotide nucleotidyltransferase activity
H7F25_06965	COG0726	polysaccharide deacetylase
H7F25_06970	COG0612	Peptidase, M16
H7F25_06980	COG1873	PFAM PRC-barrel domain
H7F25_06985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F25_06990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F25_06995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7F25_07000	COG0527	aspartate kinase activity
H7F25_07010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H7F25_07015	COG0740	serine-type endopeptidase activity
H7F25_07025	COG4980	gas vesicle protein
H7F25_07025	COG1674	ftsk spoiiie
H7F25_07030	COG2188	Transcriptional regulator
H7F25_07035	COG2814	Major facilitator Superfamily
H7F25_07040	COG2409	Drug exporters of the RND superfamily
H7F25_07040	COG1033	growth of symbiont in host cell
H7F25_07045	COG0612	Peptidase, M16
H7F25_07050	COG0612	Peptidase, M16
H7F25_07060	COG2409	Drug exporters of the RND superfamily
H7F25_07060	COG1033	growth of symbiont in host cell
H7F25_07065	COG0300	oxidoreductase activity
H7F25_07080	COG1426	Protein conserved in bacteria
H7F25_07085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7F25_07090	COG1058	Belongs to the CinA family
H7F25_07090	COG1546	Belongs to the CinA family
H7F25_07095	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H7F25_07100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F25_07105	COG1418	mRNA catabolic process
H7F25_07110	COG1692	metallophosphoesterase
H7F25_07115	COG2359	stage V sporulation protein S
H7F25_07120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F25_07125	COG1063	alcohol dehydrogenase
H7F25_07130	COG0156	8-amino-7-oxononanoate synthase activity
H7F25_07140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F25_07145	COG4550	Control of competence regulator ComK, YlbF/YmcA
H7F25_07155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H7F25_07160	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7F25_07180	COG1329	Transcriptional regulator
H7F25_07185	COG4195	phage-related replication protein
H7F25_07190	COG0457	Tetratricopeptide repeat
H7F25_07195	COG1404	Belongs to the peptidase S8 family
H7F25_07200	COG4195	phage-related replication protein
H7F25_07205	COG1764	response to oxidative stress
H7F25_07210	COG2076	Multidrug Resistance protein
H7F25_07235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H7F25_07240	COG1923	regulation of RNA biosynthetic process
H7F25_07255	COG1780	Probably involved in ribonucleotide reductase function
H7F25_07260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F25_07265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F25_07270	COG4112	unkown
H7F25_07275	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F25_07280	COG0464	growth
H7F25_07285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7F25_07290	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H7F25_07295	COG0789	Transcriptional regulator
H7F25_07300	COG0174	glutamine synthetase
H7F25_07310	COG4282	regulation of fungal-type cell wall biogenesis
H7F25_07335	COG0457	Tetratricopeptide repeat
H7F25_07340	COG5444	nuclease activity
H7F25_07360	COG5646	InterPro IPR014922
H7F25_07365	COG0457	Tetratricopeptide repeat
H7F25_07370	COG3619	membrane
H7F25_07375	COG3285	dna ligase
H7F25_07375	COG1793	dna ligase
H7F25_07380	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H7F25_07385	COG4876	unkown
H7F25_07390	COG0346	lactoylglutathione lyase activity
H7F25_07395	COG1959	2 iron, 2 sulfur cluster binding
H7F25_07400	COG0702	epimerase
H7F25_07420	COG2323	membrane
H7F25_07425	COG1309	transcriptional regulator
H7F25_07430	COG2124	cytochrome p450
H7F25_07430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F25_07435	COG3591	Belongs to the peptidase S1B family
H7F25_07440	COG3209	COG3209 Rhs family protein
H7F25_07445	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F25_07460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F25_07465	COG1388	LysM domain
H7F25_07470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7F25_07475	COG4224	UPF0291 protein
H7F25_07480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7F25_07490	COG3763	UPF0154 protein
H7F25_07500	COG0785	Cytochrome C biogenesis protein
H7F25_07505	COG4846	Membrane protein involved in cytochrome C biogenesis
H7F25_07515	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F25_07530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7F25_07535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F25_07555	COG0824	Thioesterase
H7F25_07565	COG4841	protein insertion into membrane
H7F25_07570	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H7F25_07575	COG1832	CoA-binding protein
H7F25_07580	COG0187	DNA topoisomerase II activity
H7F25_07585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7F25_07595	COG0738	Major facilitator superfamily
H7F25_07600	COG0110	maltose O-acetyltransferase activity
H7F25_07605	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F25_07610	COG1733	regulation of RNA biosynthetic process
H7F25_07620	COG1139	Iron-sulfur cluster binding protein
H7F25_07625	COG0247	lactate metabolic process
H7F25_07640	COG2205	protein histidine kinase activity
H7F25_07640	COG0745	RESPONSE REGULATOR receiver
H7F25_07640	COG3292	Two component regulator propeller
H7F25_07645	COG2197	response regulator
H7F25_07650	COG4585	Histidine kinase
H7F25_07655	COG2409	Drug exporters of the RND superfamily
H7F25_07660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F25_07665	COG0251	oxidation-reduction process
H7F25_07705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7F25_07720	COG0583	DNA-binding transcription factor activity
H7F25_07740	COG0657	acetylesterase activity
H7F25_07745	COG0789	Transcriptional regulator
H7F25_07750	COG2723	6-phospho-beta-galactosidase activity
H7F25_07755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F25_07755	COG1263	PTS System
H7F25_07755	COG2190	(PTS) system
H7F25_07770	COG2205	protein histidine kinase activity
H7F25_07775	COG0745	RESPONSE REGULATOR receiver
H7F25_07785	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F25_07790	COG1012	belongs to the aldehyde dehydrogenase family
H7F25_07795	COG1486	melibiose metabolic process
H7F25_07800	COG0395	ABC-type sugar transport system, permease component
H7F25_07805	COG1175	transmembrane transport
H7F25_07810	COG1653	transport
H7F25_07815	COG1609	Transcriptional regulator
H7F25_07820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7F25_07835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F25_07865	COG5444	nuclease activity
H7F25_07870	COG1846	Transcriptional regulator
H7F25_07875	COG2814	Major facilitator Superfamily
H7F25_07885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F25_07885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F25_07885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F25_07890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F25_07890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F25_07890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F25_07895	COG1105	Belongs to the carbohydrate kinase PfkB family
H7F25_07905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F25_07935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F25_07940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F25_07945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F25_07950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F25_07955	COG1024	Enoyl-CoA hydratase
H7F25_07960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F25_07965	COG0511	ligase activity, forming carbon-carbon bonds
H7F25_07970	COG0439	Biotin carboxylase
H7F25_07975	COG0318	PFAM AMP-dependent synthetase and ligase
H7F25_07980	COG1960	acyl-CoA dehydrogenase activity
H7F25_07985	COG1649	PFAM Uncharacterised BCR, COG1649
H7F25_07990	COG2365	Tyrosine phosphatase family
H7F25_07995	COG1349	DNA-binding transcription factor activity
H7F25_08005	COG3835	regulator
H7F25_08010	COG0277	FAD linked oxidase domain protein
H7F25_08015	COG0247	lactate metabolic process
H7F25_08040	COG0166	Belongs to the GPI family
H7F25_08045	COG2246	polysaccharide biosynthetic process
H7F25_08050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7F25_08055	COG0586	Pfam SNARE associated Golgi protein
H7F25_08060	COG1587	Uroporphyrinogen-III synthase
H7F25_08070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F25_08085	COG0534	Mate efflux family protein
H7F25_08090	COG2027	D-alanyl-D-alanine carboxypeptidase
H7F25_08095	COG4677	pectinesterase activity
H7F25_08100	COG2323	membrane
H7F25_08105	COG2146	nitrite reductase [NAD(P)H] activity
H7F25_08110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F25_08115	COG0243	molybdopterin cofactor binding
H7F25_08120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F25_08125	COG2223	nitrite transmembrane transporter activity
H7F25_08130	COG0493	'glutamate synthase
H7F25_08135	COG0067	glutamate synthase
H7F25_08135	COG0070	glutamate synthase
H7F25_08135	COG0069	glutamate synthase activity
H7F25_08140	COG0583	DNA-binding transcription factor activity
H7F25_08150	COG1132	(ABC) transporter
H7F25_08155	COG0789	Transcriptional regulator
H7F25_08155	COG4978	Transcriptional regulator
H7F25_08160	COG0454	-acetyltransferase
H7F25_08165	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F25_08170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F25_08185	COG0243	molybdopterin cofactor binding
H7F25_08195	COG1070	Carbohydrate kinase
H7F25_08200	COG2115	Belongs to the xylose isomerase family
H7F25_08215	COG2211	Major facilitator Superfamily
H7F25_08220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F25_08225	COG1994	Peptidase M50
H7F25_08245	COG1309	transcriptional regulator
H7F25_08250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F25_08255	COG3708	Transcriptional regulator
H7F25_08260	COG2378	regulation of single-species biofilm formation
H7F25_08270	COG0640	Transcriptional regulator
H7F25_08275	COG0531	amino acid
H7F25_08280	COG0741	lytic transglycosylase activity
H7F25_08285	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H7F25_08290	COG2079	MmgE PrpD family protein
H7F25_08295	COG0372	Belongs to the citrate synthase family
H7F25_08300	COG2322	membrane
H7F25_08310	COG1388	LysM domain
H7F25_08310	COG3584	3D domain protein
H7F25_08315	COG0514	ATP-dependent DNA helicase (RecQ)
H7F25_08325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F25_08350	COG1012	belongs to the aldehyde dehydrogenase family
H7F25_08355	COG1657	PFAM Prenyltransferase squalene oxidase
H7F25_08360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F25_08365	COG0385	Bile acid
H7F25_08370	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F25_08375	COG0567	Dehydrogenase, E1 component
H7F25_08380	COG4548	von Willebrand factor, type A
H7F25_08385	COG0714	Associated with various cellular activities
H7F25_08390	COG2032	superoxide dismutase activity
H7F25_08395	COG1388	LysM domain
H7F25_08395	COG0791	NLP P60 protein
H7F25_08400	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H7F25_08405	COG0534	Mate efflux family protein
H7F25_08410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F25_08415	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F25_08425	COG2962	Rard protein
H7F25_08440	COG1733	regulation of RNA biosynthetic process
H7F25_08445	COG0778	Nitroreductase
H7F25_08455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F25_08460	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H7F25_08465	COG3409	Peptidoglycan-binding domain 1 protein
H7F25_08465	COG0793	Belongs to the peptidase S41A family
H7F25_08470	COG2226	methyltransferase
H7F25_08480	COG1876	peptidase activity
H7F25_08485	COG0813	purine-nucleoside phosphorylase activity
H7F25_08495	COG0671	phosphoesterase, PA-phosphatase related
H7F25_08510	COG4479	Belongs to the UPF0346 family
H7F25_08520	COG1509	lysine 2,3-aminomutase activity
H7F25_08525	COG3829	transcription factor binding
H7F25_08530	COG0463	Glycosyl transferase, family 2
H7F25_08545	COG4641	Protein conserved in bacteria
H7F25_08555	COG1086	Polysaccharide biosynthesis protein
H7F25_08560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F25_08565	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F25_08570	COG1846	Transcriptional regulator
H7F25_08590	COG4698	Protein conserved in bacteria
H7F25_08595	COG2755	lipolytic protein G-D-S-L family
H7F25_08600	COG1999	signal sequence binding
H7F25_08615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F25_08620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7F25_08625	COG1272	protein, Hemolysin III
H7F25_08630	COG0204	Acyl-transferase
H7F25_08635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7F25_08640	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H7F25_08645	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F25_08655	COG2136	Putative SAM-dependent methyltransferase
H7F25_08655	COG2521	methyltransferase
H7F25_08665	COG0129	dihydroxy-acid dehydratase activity
H7F25_08670	COG1413	lyase activity
H7F25_08675	COG1418	mRNA catabolic process
H7F25_08680	COG0386	Belongs to the glutathione peroxidase family
H7F25_08685	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H7F25_08690	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H7F25_08695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F25_08705	COG1278	Cold shock
H7F25_08720	COG0328	RNA-DNA hybrid ribonuclease activity
H7F25_08725	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H7F25_08730	COG0328	RNA-DNA hybrid ribonuclease activity
H7F25_08740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F25_08750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F25_08760	COG1755	Isoprenylcysteine carboxyl methyltransferase
H7F25_08765	COG3424	synthase
H7F25_08775	COG0726	polysaccharide deacetylase
H7F25_08780	COG2233	PERMEase
H7F25_08785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F25_08790	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H7F25_08795	COG1199	ATP-dependent helicase activity
H7F25_08805	COG0116	Belongs to the methyltransferase superfamily
H7F25_08815	COG3599	regulation of cell shape
H7F25_08820	COG4474	Belongs to the UPF0398 family
H7F25_08830	COG3359	exonuclease
H7F25_08835	COG1111	helicase
H7F25_08835	COG1205	dead DEAH box helicase
H7F25_08840	COG1902	pentaerythritol trinitrate reductase activity
H7F25_08845	COG2190	(PTS) system
H7F25_08850	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F25_08880	COG3331	DNA recombination
H7F25_08885	COG4499	WXG100 protein secretion system (Wss), protein YukC
H7F25_08885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F25_08895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7F25_08900	COG3935	DnaD domain protein
H7F25_08905	COG0017	Asparaginyl-tRNA synthetase
H7F25_08910	COG5353	protein conserved in bacteria
H7F25_08920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7F25_08920	COG1199	ATP-dependent helicase activity
H7F25_08925	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H7F25_08930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H7F25_08935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H7F25_08945	COG0617	tRNA 3'-terminal CCA addition
H7F25_08950	COG0438	transferase activity, transferring glycosyl groups
H7F25_08955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F25_08960	COG1803	Methylglyoxal synthase
H7F25_08965	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H7F25_08970	COG1694	Mazg nucleotide pyrophosphohydrolase
H7F25_08975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F25_08985	COG4347	Protein of unknown function (DUF1405)
H7F25_08990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F25_08990	COG2010	Cytochrome c
H7F25_08995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F25_09000	COG0723	plastoquinol--plastocyanin reductase activity
H7F25_09010	COG5582	Belongs to the UPF0302 family
H7F25_09015	COG0457	Tetratricopeptide repeat
H7F25_09020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7F25_09025	COG0287	Prephenate dehydrogenase
H7F25_09030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F25_09035	COG0159	tryptophan synthase activity
H7F25_09040	COG0133	tryptophan synthase activity
H7F25_09050	COG0134	indole-3-glycerol-phosphate synthase activity
H7F25_09065	COG4401	Chorismate mutase type I
H7F25_09070	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H7F25_09075	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H7F25_09080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H7F25_09085	COG0105	UTP biosynthetic process
H7F25_09090	COG0142	geranyltranstransferase activity
H7F25_09095	COG2226	methyltransferase
H7F25_09100	COG0142	geranyltranstransferase activity
H7F25_09110	COG0302	gtp cyclohydrolase
H7F25_09115	COG0776	regulation of translation
H7F25_09120	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F25_09135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H7F25_09140	COG1160	GTP binding
H7F25_09165	COG1304	FMN binding
H7F25_09170	COG0539	negative regulation of cytoplasmic translation
H7F25_09175	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H7F25_09185	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H7F25_09190	COG2959	enzyme of heme biosynthesis
H7F25_09195	COG3773	Cell wall hydrolase
H7F25_09195	COG3409	Peptidoglycan-binding domain 1 protein
H7F25_09200	COG2339	peptidase activity
H7F25_09205	COG0492	ferredoxin-NADP+ reductase activity
H7F25_09210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F25_09215	COG4862	establishment of competence for transformation
H7F25_09220	COG1408	metallophosphoesterase
H7F25_09230	COG1388	LysM domain
H7F25_09235	COG1266	CAAX protease self-immunity
H7F25_09240	COG0514	ATP-dependent DNA helicase (RecQ)
H7F25_09245	COG4955	Helix-turn-helix domain
H7F25_09250	COG1141	Ferredoxin
H7F25_09255	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H7F25_09260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F25_09265	COG5632	N-Acetylmuramoyl-L-alanine amidase
H7F25_09265	COG3409	Peptidoglycan-binding domain 1 protein
H7F25_09275	COG1595	DNA-templated transcription, initiation
H7F25_09280	COG5002	protein histidine kinase activity
H7F25_09285	COG0745	RESPONSE REGULATOR receiver
H7F25_09290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F25_09295	COG1333	cytochrome c biogenesis protein
H7F25_09300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F25_09305	COG1187	pseudouridine synthase activity
H7F25_09310	COG0700	Nucleoside recognition
H7F25_09315	COG2715	membrane protein required for spore maturation
H7F25_09320	COG1686	Belongs to the peptidase S11 family
H7F25_09330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7F25_09335	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H7F25_09345	COG1547	Domain of unknown function (DUF309)
H7F25_09350	COG0456	acetyltransferase
H7F25_09355	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H7F25_09360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F25_09360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F25_09365	COG0307	riboflavin synthase, alpha
H7F25_09385	COG2814	Major facilitator Superfamily
H7F25_09390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7F25_09395	COG4086	secreted protein
H7F25_09400	COG0019	diaminopimelate decarboxylase activity
H7F25_09405	COG0697	spore germination
H7F25_09420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F25_09440	COG1191	sigma factor activity
H7F25_09445	COG2172	sigma factor antagonist activity
H7F25_09455	COG1686	Belongs to the peptidase S11 family
H7F25_09460	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H7F25_09465	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H7F25_09470	COG4974	Belongs to the 'phage' integrase family
H7F25_09480	COG0735	belongs to the Fur family
H7F25_09485	COG1300	Membrane
H7F25_09490	COG1404	Belongs to the peptidase S8 family
H7F25_09500	COG2153	protein acetylation
H7F25_09505	COG1379	DNA repair
H7F25_09510	COG0494	nUDIX hydrolase
H7F25_09515	COG0667	Aldo Keto reductase
H7F25_09530	COG1073	alpha beta
H7F25_09535	COG0457	Tetratricopeptide repeat
H7F25_09550	COG4918	Iron-sulphur cluster biosynthesis
H7F25_09555	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H7F25_09555	COG0456	acetyltransferase
H7F25_09560	COG0456	acetyltransferase
H7F25_09570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F25_09580	COG2211	Major facilitator Superfamily
H7F25_09585	COG1072	(Pantothenic acid kinase))
H7F25_09590	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7F25_09595	COG0300	oxidoreductase activity
H7F25_09600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F25_09605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F25_09615	COG4187	Peptidase family M20/M25/M40
H7F25_09620	COG1902	pentaerythritol trinitrate reductase activity
H7F25_09625	COG0596	Alpha beta hydrolase
H7F25_09630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F25_09640	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H7F25_09645	COG2188	Transcriptional regulator
H7F25_09650	COG2723	6-phospho-beta-galactosidase activity
H7F25_09655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F25_09660	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F25_09665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F25_09670	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_09680	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H7F25_09685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F25_09700	COG0706	membrane insertase activity
H7F25_09710	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7F25_09715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F25_09720	COG0346	lactoylglutathione lyase activity
H7F25_09730	COG1376	ErfK ybiS ycfS ynhG family protein
H7F25_09735	COG4129	membrane
H7F25_09740	COG1126	abc transporter atp-binding protein
H7F25_09745	COG0765	amino acid transport
H7F25_09750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F25_09760	COG1597	lipid kinase activity
H7F25_09770	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F25_09775	COG0022	dehydrogenase e1 component
H7F25_09780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F25_09785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F25_09790	COG3426	butyrate kinase activity
H7F25_09795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F25_09800	COG0280	phosphate acetyltransferase
H7F25_09805	COG3290	protein histidine kinase activity
H7F25_09805	COG3829	transcription factor binding
H7F25_09815	COG0584	glycerophosphoryl diester phosphodiesterase
H7F25_09820	COG0457	Tetratricopeptide repeat
H7F25_09830	COG0745	RESPONSE REGULATOR receiver
H7F25_09835	COG0750	zinc metalloprotease
H7F25_09840	COG0497	DNA recombination
H7F25_09845	COG1438	arginine binding
H7F25_09850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H7F25_09855	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H7F25_09860	COG0142	geranyltranstransferase activity
H7F25_09865	COG1722	exodeoxyribonuclease VII activity
H7F25_09870	COG1570	exodeoxyribonuclease VII activity
H7F25_09875	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H7F25_09880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F25_09885	COG1302	Protein conserved in bacteria
H7F25_09890	COG0439	Biotin carboxylase
H7F25_09895	COG0511	ligase activity, forming carbon-carbon bonds
H7F25_09935	COG3854	ATPases associated with a variety of cellular activities
H7F25_09945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H7F25_09950	COG0006	proline dipeptidase activity
H7F25_09955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H7F25_09965	COG3872	metal-dependent enzyme
H7F25_09975	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7F25_09980	COG1321	iron dependent repressor
H7F25_09985	COG0095	Lipoate-protein ligase
H7F25_09990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F25_09995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F25_10000	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F25_10005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H7F25_10010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7F25_10035	COG0681	Belongs to the peptidase S26 family
H7F25_10070	COG4970	Tfp pilus assembly protein FimT
H7F25_10075	COG4537	Required for transformation and DNA binding
H7F25_10080	COG1459	type II secretion system
H7F25_10085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7F25_10090	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F25_10100	COG1393	Belongs to the ArsC family
H7F25_10110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F25_10120	COG0011	TIGRFAM Protein of
H7F25_10125	COG2814	Major facilitator Superfamily
H7F25_10130	COG2866	Carboxypeptidase
H7F25_10135	COG1368	sulfuric ester hydrolase activity
H7F25_10140	COG1940	carbohydrate kinase activity
H7F25_10145	COG4483	Protein conserved in bacteria
H7F25_10150	COG0705	Rhomboid family
H7F25_10150	COG0457	Tetratricopeptide repeat
H7F25_10160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7F25_10165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F25_10175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F25_10180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F25_10185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F25_10190	COG0581	inorganic phosphate transmembrane transporter activity
H7F25_10195	COG0573	inorganic phosphate transmembrane transporter activity
H7F25_10200	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7F25_10205	COG0768	penicillin binding
H7F25_10210	COG0477	Major facilitator Superfamily
H7F25_10215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F25_10220	COG2839	Protein conserved in bacteria
H7F25_10225	COG5521	maltodextrose utilization protein MalA
H7F25_10230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F25_10235	COG1388	LysM domain
H7F25_10240	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H7F25_10245	COG4709	membrane
H7F25_10250	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
H7F25_10255	COG1940	carbohydrate kinase activity
H7F25_10260	COG0735	belongs to the Fur family
H7F25_10265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F25_10270	COG1121	(ABC) transporter
H7F25_10275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F25_10290	COG0513	Belongs to the DEAD box helicase family
H7F25_10300	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H7F25_10305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7F25_10310	COG2384	SAM-dependent methyltransferase
H7F25_10315	COG2010	Cytochrome c
H7F25_10320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7F25_10325	COG0358	DNA primase activity
H7F25_10330	COG1671	Belongs to the UPF0178 family
H7F25_10335	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H7F25_10340	COG0517	IMP dehydrogenase activity
H7F25_10345	COG0751	glycine-tRNA ligase activity
H7F25_10350	COG0752	glycyl-tRNA synthetase alpha subunit
H7F25_10355	COG1381	Involved in DNA repair and RecF pathway recombination
H7F25_10365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7F25_10370	COG0295	cytidine deaminase activity
H7F25_10375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H7F25_10380	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H7F25_10385	COG1480	7TM receptor with intracellular HD hydrolase
H7F25_10390	COG1702	phosphate starvation-inducible protein PhoH
H7F25_10395	COG0561	phosphatase activity
H7F25_10410	COG4864	UPF0365 protein
H7F25_10415	COG1030	water channel activity
H7F25_10420	COG1610	YqeY-like protein
H7F25_10430	COG1283	sodium-dependent phosphate transmembrane transporter activity
H7F25_10435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F25_10440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7F25_10445	COG2264	protein methyltransferase activity
H7F25_10450	COG0484	heat shock protein binding
H7F25_10455	COG0443	Heat shock 70 kDa protein
H7F25_10460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H7F25_10465	COG1420	regulation of RNA biosynthetic process
H7F25_10470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F25_10475	COG0481	GTPase activity
H7F25_10485	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F25_10490	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H7F25_10495	COG0268	Binds directly to 16S ribosomal RNA
H7F25_10500	COG1466	dna polymerase III delta subunit
H7F25_10510	COG0658	competence protein
H7F25_10510	COG2333	competence protein COMEC
H7F25_10515	COG2131	deaminase
H7F25_10520	COG1555	photosystem II stabilization
H7F25_10525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F25_10530	COG2226	methyltransferase
H7F25_10535	COG0799	negative regulation of ribosome biogenesis
H7F25_10540	COG1713	HD superfamily hydrolase involved in NAD metabolism
H7F25_10545	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H7F25_10550	COG1534	Rna-binding protein
H7F25_10555	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F25_10560	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F25_10565	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H7F25_10580	COG2755	lipolytic protein G-D-S-L family
H7F25_10590	COG0457	Tetratricopeptide repeat
H7F25_10600	COG2186	Transcriptional regulator
H7F25_10615	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_10620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H7F25_10625	COG3959	Transketolase, thiamine diphosphate binding domain
H7F25_10650	COG0726	polysaccharide deacetylase
H7F25_10685	COG1131	(ABC) transporter
H7F25_10705	COG2160	L-arabinose isomerase activity
H7F25_10720	COG1609	Transcriptional regulator
H7F25_10730	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H7F25_10735	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H7F25_10740	COG1733	regulation of RNA biosynthetic process
H7F25_10745	COG0657	acetylesterase activity
H7F25_10760	COG1309	transcriptional regulator
H7F25_10765	COG0109	protoheme IX farnesyltransferase activity
H7F25_10770	COG2602	Beta-lactamase
H7F25_10775	COG1960	acyl-CoA dehydrogenase activity
H7F25_10780	COG1126	abc transporter atp-binding protein
H7F25_10790	COG0765	amino acid transport
H7F25_10800	COG3546	catalase activity
H7F25_10805	COG1063	alcohol dehydrogenase
H7F25_10815	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_10825	COG1115	amino acid carrier protein
H7F25_10830	COG0583	DNA-binding transcription factor activity
H7F25_10835	COG0842	Transport permease protein
H7F25_10840	COG1511	domain protein
H7F25_10840	COG0842	Transport permease protein
H7F25_10845	COG1131	(ABC) transporter
H7F25_10850	COG2226	methyltransferase
H7F25_10855	COG1063	alcohol dehydrogenase
H7F25_10860	COG2226	methyltransferase
H7F25_10885	COG0626	cystathionine gamma-synthase activity
H7F25_10890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F25_10895	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7F25_10900	COG2226	methyltransferase
H7F25_10915	COG0768	penicillin binding
H7F25_10920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7F25_10930	COG0572	uridine kinase
H7F25_10935	COG0826	peptidase U32
H7F25_10940	COG0826	peptidase U32
H7F25_10945	COG4122	O-methyltransferase activity
H7F25_10950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F25_10955	COG0183	Belongs to the thiolase family
H7F25_10960	COG0318	PFAM AMP-dependent synthetase and ligase
H7F25_10965	COG1268	BioY protein
H7F25_10970	COG3906	Belongs to the UPF0473 family
H7F25_10975	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7F25_10980	COG4472	Bacterial protein of unknown function (DUF965)
H7F25_10985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7F25_10990	COG0628	permease
H7F25_10995	COG1126	abc transporter atp-binding protein
H7F25_11000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F25_11005	COG0765	amino acid transport
H7F25_11010	COG0765	amino acid transport
H7F25_11025	COG3881	PFAM PRC-barrel domain
H7F25_11030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7F25_11035	COG0457	Tetratricopeptide repeat
H7F25_11040	COG0482	sulfurtransferase activity
H7F25_11045	COG1104	cysteine desulfurase activity
H7F25_11050	COG1959	2 iron, 2 sulfur cluster binding
H7F25_11055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7F25_11060	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7F25_11075	COG0124	histidyl-tRNA synthetase
H7F25_11085	COG3103	Sh3 type 3 domain protein
H7F25_11085	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F25_11085	COG4991	sh3 domain protein
H7F25_11090	COG1490	D-aminoacyl-tRNA deacylase activity
H7F25_11095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7F25_11100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F25_11105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7F25_11105	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H7F25_11110	COG5416	Lipopolysaccharide assembly protein A domain
H7F25_11115	COG0490	domain, Protein
H7F25_11120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F25_11120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F25_11130	COG2244	polysaccharide biosynthetic process
H7F25_11135	COG2323	membrane
H7F25_11145	COG1862	Preprotein translocase
H7F25_11150	COG0343	queuine tRNA-ribosyltransferase activity
H7F25_11155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H7F25_11165	COG2255	four-way junction helicase activity
H7F25_11170	COG0632	four-way junction helicase activity
H7F25_11180	COG2112	serine threonine protein kinase
H7F25_11195	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H7F25_11210	COG1388	LysM domain
H7F25_11210	COG1388	LysM domain
H7F25_11215	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7F25_11220	COG0157	Belongs to the NadC ModD family
H7F25_11225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H7F25_11230	COG1104	cysteine desulfurase activity
H7F25_11235	COG1827	regulation of RNA biosynthetic process
H7F25_11240	COG0077	Prephenate dehydratase
H7F25_11245	COG4492	Belongs to the UPF0735 family
H7F25_11250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H7F25_11255	COG3290	protein histidine kinase activity
H7F25_11260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H7F25_11265	COG2868	ribosomal protein
H7F25_11270	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H7F25_11275	COG1994	Peptidase M50
H7F25_11280	COG0739	heme binding
H7F25_11285	COG2894	cell division
H7F25_11290	COG0850	regulation of cytokinetic process
H7F25_11295	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H7F25_11305	COG1077	Cell shape determining protein MreB Mrl
H7F25_11310	COG2003	Belongs to the UPF0758 family
H7F25_11315	COG0424	maF-like protein
H7F25_11325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H7F25_11330	COG0285	dihydrofolate synthase activity
H7F25_11335	COG0525	valine-tRNA ligase activity
H7F25_11340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F25_11345	COG1388	LysM domain
H7F25_11350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F25_11355	COG0113	porphobilinogen synthase activity
H7F25_11360	COG1587	Uroporphyrinogen-III synthase
H7F25_11365	COG0181	hydroxymethylbilane synthase activity
H7F25_11370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F25_11375	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H7F25_11385	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H7F25_11390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7F25_11395	COG1067	ATP-dependent peptidase activity
H7F25_11395	COG0470	DNA polymerase III
H7F25_11400	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H7F25_11405	COG0544	peptidyl-prolyl cis-trans isomerase activity
H7F25_11410	COG0457	Tetratricopeptide repeat
H7F25_11410	COG1477	protein flavinylation
H7F25_11415	COG0066	3-isopropylmalate dehydratase activity
H7F25_11420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7F25_11425	COG0473	3-isopropylmalate dehydrogenase activity
H7F25_11430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F25_11435	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H7F25_11440	COG0440	acetolactate synthase activity
H7F25_11445	COG0028	Belongs to the TPP enzyme family
H7F25_11450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F25_11455	COG2706	6-phosphogluconolactonase activity
H7F25_11460	COG3339	Conserved Protein
H7F25_11465	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H7F25_11470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F25_11475	COG1696	Membrane protein involved in D-alanine export
H7F25_11525	COG0622	Phosphoesterase
H7F25_11530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H7F25_11535	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H7F25_11540	COG5401	PFAM Sporulation and spore germination
H7F25_11545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7F25_11550	COG1846	Transcriptional regulator
H7F25_11555	COG2197	response regulator
H7F25_11560	COG2851	Citrate transporter
H7F25_11565	COG0583	DNA-binding transcription factor activity
H7F25_11570	COG2828	Protein conserved in bacteria
H7F25_11580	COG0824	Thioesterase
H7F25_11585	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7F25_11590	COG1053	succinate dehydrogenase
H7F25_11595	COG2009	succinate dehydrogenase
H7F25_11600	COG1719	4-vinyl reductase, 4VR
H7F25_11605	COG0527	aspartate kinase activity
H7F25_11610	COG0322	excinuclease ABC activity
H7F25_11615	COG3118	belongs to the thioredoxin family
H7F25_11620	COG3534	alpha-L-arabinofuranosidase
H7F25_11625	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H7F25_11630	COG2086	electron transfer activity
H7F25_11635	COG1024	Enoyl-CoA hydratase
H7F25_11640	COG1309	transcriptional regulator
H7F25_11645	COG0318	PFAM AMP-dependent synthetase and ligase
H7F25_11655	COG3766	membrane
H7F25_11660	COG1193	negative regulation of DNA recombination
H7F25_11665	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7F25_11665	COG1796	DNA polymerase
H7F25_11670	COG1286	toxin biosynthetic process
H7F25_11675	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
H7F25_11680	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F25_11690	COG0072	phenylalanine-tRNA ligase activity
H7F25_11690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F25_11695	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H7F25_11700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F25_11710	COG1966	Carbon starvation protein
H7F25_11715	COG1363	Peptidase, m42
H7F25_11725	COG3326	Membrane
H7F25_11730	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H7F25_11735	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H7F25_11740	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H7F25_11745	COG1346	cytolysis
H7F25_11755	COG3279	Response regulator of the LytR AlgR family
H7F25_11760	COG3275	phosphorelay sensor kinase activity
H7F25_11765	COG1011	Hydrolase
H7F25_11775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F25_11785	COG0398	Pfam SNARE associated Golgi protein
H7F25_11790	COG1484	DNA-dependent DNA replication
H7F25_11795	COG3611	Membrane attachment protein
H7F25_11800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H7F25_11810	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H7F25_11815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F25_11820	COG0237	dephospho-CoA kinase activity
H7F25_11825	COG1971	Probably functions as a manganese efflux pump
H7F25_11830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H7F25_11835	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F25_11835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F25_11840	COG5002	protein histidine kinase activity
H7F25_11845	COG0745	RESPONSE REGULATOR receiver
H7F25_11850	COG0039	L-malate dehydrogenase activity
H7F25_11855	COG0538	isocitrate dehydrogenase activity
H7F25_11860	COG0372	Belongs to the citrate synthase family
H7F25_11865	COG2707	UPF0756 membrane protein
H7F25_11870	COG0628	permease
H7F25_11875	COG3030	protein affecting phage T7 exclusion by the F plasmid
H7F25_11885	COG0205	6-phosphofructokinase activity
H7F25_11890	COG0825	malonyl-CoA metabolic process
H7F25_11895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H7F25_11900	COG0281	malic enzyme
H7F25_11905	COG0587	DNA-directed DNA polymerase activity
H7F25_11925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H7F25_11935	COG4109	DRTGG domain
H7F25_11940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F25_11945	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_11955	COG0165	Argininosuccinate lyase
H7F25_11960	COG0137	argininosuccinate synthase activity
H7F25_11965	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7F25_11970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7F25_11975	COG0827	DNA restriction-modification system
H7F25_11980	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H7F25_11985	COG3874	Sporulation protein YtfJ
H7F25_11995	COG1714	RDD family
H7F25_12000	COG0616	signal peptide processing
H7F25_12005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F25_12015	COG3239	Fatty acid desaturase
H7F25_12020	COG4585	Histidine kinase
H7F25_12025	COG2197	response regulator
H7F25_12030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F25_12035	COG0745	RESPONSE REGULATOR receiver
H7F25_12040	COG0642	Histidine kinase
H7F25_12045	COG1136	(ABC) transporter
H7F25_12050	COG0577	efflux transmembrane transporter activity
H7F25_12055	COG0402	S-adenosylhomocysteine deaminase activity
H7F25_12070	COG1279	arginine transmembrane transporter activity
H7F25_12090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F25_12100	COG0301	tRNA thio-modification
H7F25_12105	COG1104	cysteine desulfurase activity
H7F25_12110	COG1114	Component of the transport system for branched-chain amino acids
H7F25_12115	COG1114	Component of the transport system for branched-chain amino acids
H7F25_12120	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
H7F25_12125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7F25_12130	COG1309	transcriptional regulator
H7F25_12135	COG1956	GAF domain-containing protein
H7F25_12140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H7F25_12145	COG1335	isochorismatase
H7F25_12155	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H7F25_12160	COG2329	Antibiotic biosynthesis monooxygenase
H7F25_12165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7F25_12170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F25_12175	COG0454	-acetyltransferase
H7F25_12180	COG0517	IMP dehydrogenase activity
H7F25_12185	COG0123	including yeast histone deacetylase and acetoin utilization protein
H7F25_12190	COG1609	Transcriptional regulator
H7F25_12195	COG1605	Chorismate mutase
H7F25_12195	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H7F25_12200	COG3118	belongs to the thioredoxin family
H7F25_12205	COG4980	gas vesicle protein
H7F25_12210	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H7F25_12215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7F25_12220	COG1674	ftsk spoiiie
H7F25_12225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F25_12230	COG4848	Belongs to the UPF0354 family
H7F25_12235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F25_12250	COG1363	Peptidase, m42
H7F25_12255	COG5584	Small secreted protein
H7F25_12260	COG0281	malic enzyme
H7F25_12265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F25_12270	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7F25_12280	COG0510	thiamine kinase activity
H7F25_12285	COG1597	lipid kinase activity
H7F25_12295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7F25_12300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F25_12305	COG3340	Belongs to the peptidase S51 family
H7F25_12310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F25_12315	COG2252	PERMEase
H7F25_12320	COG1349	DNA-binding transcription factor activity
H7F25_12325	COG1187	pseudouridine synthase activity
H7F25_12330	COG2244	polysaccharide biosynthetic process
H7F25_12335	COG2081	HI0933 family
H7F25_12345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7F25_12350	COG3196	Protein conserved in bacteria
H7F25_12360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F25_12365	COG5578	integral membrane protein
H7F25_12370	COG0673	inositol 2-dehydrogenase activity
H7F25_12375	COG1653	transport
H7F25_12380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H7F25_12385	COG4209	transmembrane transport
H7F25_12390	COG2207	Transcriptional regulator
H7F25_12395	COG1733	regulation of RNA biosynthetic process
H7F25_12400	COG2814	Major facilitator Superfamily
H7F25_12405	COG0656	L-ascorbic acid biosynthetic process
H7F25_12410	COG1653	transport
H7F25_12415	COG0395	ABC-type sugar transport system, permease component
H7F25_12420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F25_12425	COG1073	alpha beta
H7F25_12430	COG0495	leucyl-tRNA aminoacylation
H7F25_12440	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F25_12440	COG2202	Pas domain
H7F25_12445	COG2433	Pfam Transposase IS66
H7F25_12450	COG0577	efflux transmembrane transporter activity
H7F25_12455	COG1136	(ABC) transporter
H7F25_12465	COG1131	(ABC) transporter
H7F25_12470	COG1725	Transcriptional regulator
H7F25_12485	COG1242	4 iron, 4 sulfur cluster binding
H7F25_12490	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H7F25_12500	COG2267	carboxylic ester hydrolase activity
H7F25_12505	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7F25_12510	COG0367	asparagine synthase
H7F25_12515	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H7F25_12520	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H7F25_12530	COG1506	peptidase
H7F25_12535	COG1233	COG1233 Phytoene dehydrogenase and related
H7F25_12555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F25_12560	COG1116	anion transmembrane transporter activity
H7F25_12565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F25_12570	COG0494	nUDIX hydrolase
H7F25_12575	COG2310	stress, protein
H7F25_12590	COG4824	toxin secretion phage lysis holin
H7F25_12600	COG0783	Belongs to the Dps family
H7F25_12615	COG1854	S-ribosylhomocysteine lyase activity
H7F25_12620	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7F25_12625	COG0288	reversible hydration of carbon dioxide
H7F25_12630	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7F25_12630	COG3443	Belongs to the bacterial solute-binding protein 9 family
H7F25_12635	COG0254	rRNA binding
H7F25_12640	COG1271	oxidase subunit
H7F25_12645	COG1294	oxidase, subunit
H7F25_12660	COG4948	Mandelate Racemase Muconate Lactonizing
H7F25_12665	COG0318	PFAM AMP-dependent synthetase and ligase
H7F25_12670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H7F25_12675	COG0596	Alpha beta hydrolase
H7F25_12680	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H7F25_12685	COG1169	isochorismate synthase
H7F25_12690	COG1575	Belongs to the MenA family. Type 1 subfamily
H7F25_12695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F25_12825	COG3859	Proton-coupled thiamine transporter YuaJ
H7F25_12830	COG1247	-acetyltransferase
H7F25_12835	COG3339	Conserved Protein
H7F25_12840	COG0772	Belongs to the SEDS family
H7F25_12845	COG0772	Belongs to the SEDS family
H7F25_12850	COG2268	Band 7 protein
H7F25_12855	COG1585	Membrane protein implicated in regulation of membrane protease activity
H7F25_12860	COG2318	DinB family
H7F25_12865	COG1454	alcohol dehydrogenase
H7F25_12870	COG1012	belongs to the aldehyde dehydrogenase family
H7F25_12875	COG1510	regulation of RNA biosynthetic process
H7F25_12900	COG3409	Peptidoglycan-binding domain 1 protein
H7F25_12900	COG5632	N-Acetylmuramoyl-L-alanine amidase
H7F25_12955	COG3778	Protein conserved in bacteria
H7F25_12960	COG3299	homolog of phage Mu protein gp47
H7F25_12965	COG3628	GPW Gp25 family protein
H7F25_12975	COG4193	domain, Protein
H7F25_12980	COG1652	LysM domain
H7F25_12985	COG5280	Phage tail tape measure protein TP901
H7F25_12985	COG3953	SLT domain
H7F25_12985	COG5280	Phage tail tape measure protein TP901
H7F25_12985	COG3953	SLT domain
H7F25_13040	COG4653	Phage capsid family
H7F25_13045	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H7F25_13050	COG5518	Phage portal protein
H7F25_13055	COG1783	phage Terminase large subunit
H7F25_13060	COG5484	DNA packaging
H7F25_13065	COG1595	DNA-templated transcription, initiation
H7F25_13075	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H7F25_13095	COG1396	sequence-specific DNA binding
H7F25_13105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H7F25_13115	COG1968	undecaprenyl-diphosphatase activity
H7F25_13120	COG0628	permease
H7F25_13130	COG0673	inositol 2-dehydrogenase activity
H7F25_13135	COG0693	protein deglycase activity
H7F25_13140	COG0840	transmembrane signaling receptor activity
H7F25_13145	COG0840	transmembrane signaling receptor activity
H7F25_13150	COG0840	transmembrane signaling receptor activity
H7F25_13155	COG0840	transmembrane signaling receptor activity
H7F25_13170	COG2070	2-Nitropropane dioxygenase
H7F25_13175	COG0432	Pfam Uncharacterised protein family UPF0047
H7F25_13180	COG1253	flavin adenine dinucleotide binding
H7F25_13185	COG2738	Putative neutral zinc metallopeptidase
H7F25_13195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7F25_13210	COG0166	Belongs to the GPI family
H7F25_13215	COG1979	alcohol dehydrogenase
H7F25_13220	COG1979	alcohol dehydrogenase
H7F25_13225	COG2155	Conserved Protein
H7F25_13230	COG1098	S1 RNA binding domain
H7F25_13235	COG0436	Aminotransferase
H7F25_13240	COG1522	sequence-specific DNA binding
H7F25_13245	COG2267	carboxylic ester hydrolase activity
H7F25_13255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H7F25_13260	COG2205	protein histidine kinase activity
H7F25_13275	COG5018	Exonuclease
H7F25_13280	COG2814	Major facilitator Superfamily
H7F25_13285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F25_13290	COG3011	Protein conserved in bacteria
H7F25_13300	COG3290	protein histidine kinase activity
H7F25_13305	COG4565	transcriptional regulatory protein
H7F25_13310	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F25_13315	COG3845	ABC transporter
H7F25_13320	COG4603	Belongs to the binding-protein-dependent transport system permease family
H7F25_13325	COG1079	Belongs to the binding-protein-dependent transport system permease family
H7F25_13330	COG3493	citrate carrier protein
H7F25_13340	COG2111	Na H antiporter
H7F25_13340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7F25_13345	COG2111	Na H antiporter
H7F25_13350	COG1006	Multisubunit Na H antiporter MnhC subunit
H7F25_13355	COG0651	ATP synthesis coupled electron transport
H7F25_13360	COG1863	multisubunit Na H antiporter MnhE subunit
H7F25_13365	COG2212	antiporter activity
H7F25_13370	COG1320	monovalent cation:proton antiporter activity
H7F25_13375	COG2050	protein possibly involved in aromatic compounds catabolism
H7F25_13380	COG2197	response regulator
H7F25_13385	COG4585	Histidine kinase
H7F25_13395	COG0142	geranyltranstransferase activity
H7F25_13410	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H7F25_13415	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H7F25_13420	COG1335	isochorismatase
H7F25_13425	COG5506	Protein of unknown function (DUF1694)
H7F25_13445	COG0628	permease
H7F25_13460	COG1418	mRNA catabolic process
H7F25_13465	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_13475	COG1511	domain protein
H7F25_13480	COG0433	COG0433 Predicted ATPase
H7F25_13480	COG1674	ftsk spoiiie
H7F25_13485	COG4499	WXG100 protein secretion system (Wss), protein YukC
H7F25_13490	COG5417	Belongs to the EsaB family
H7F25_13495	COG4842	Belongs to the WXG100 family
H7F25_13500	COG2508	Transcriptional regulator
H7F25_13500	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7F25_13505	COG0686	Belongs to the AlaDH PNT family
H7F25_13510	COG1268	BioY protein
H7F25_13515	COG4326	sporulation control protein
H7F25_13520	COG2056	Na+-H+ antiporter family
H7F25_13525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7F25_13530	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H7F25_13535	COG3584	3D domain protein
H7F25_13550	COG1252	NADH dehydrogenase
H7F25_13555	COG0492	ferredoxin-NADP+ reductase activity
H7F25_13565	COG0789	Transcriptional regulator
H7F25_13570	COG0316	Belongs to the HesB IscA family
H7F25_13575	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H7F25_13580	COG4844	belongs to the
H7F25_13585	COG1252	NADH dehydrogenase
H7F25_13595	COG4837	Protein of unknown function (DUF1462)
H7F25_13600	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H7F25_13605	COG4946	Tricorn protease homolog
H7F25_13605	COG1506	peptidase
H7F25_13605	COG0823	Involved in the tonB-independent uptake of proteins
H7F25_13610	COG0083	homoserine kinase activity
H7F25_13615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7F25_13620	COG0460	homoserine dehydrogenase
H7F25_13625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F25_13630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F25_13635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F25_13640	COG0647	UMP catabolic process
H7F25_13645	COG2445	Protein of unknown function DUF86
H7F25_13650	COG4470	Protein conserved in bacteria
H7F25_13660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7F25_13665	COG0739	heme binding
H7F25_13675	COG3377	Domain of unknown function (DUF1805)
H7F25_13680	COG0737	Belongs to the 5'-nucleotidase family
H7F25_13685	COG1801	Protein of unknown function DUF72
H7F25_13690	COG2508	Transcriptional regulator
H7F25_13695	COG2140	Oxalate decarboxylase
H7F25_13700	COG2814	Major facilitator Superfamily
H7F25_13705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H7F25_13710	COG2356	endonuclease I
H7F25_13720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F25_13725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F25_13730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F25_13740	COG0561	phosphatase activity
H7F25_13750	COG0642	Histidine kinase
H7F25_13750	COG5002	protein histidine kinase activity
H7F25_13755	COG0745	RESPONSE REGULATOR receiver
H7F25_13760	COG2311	Membrane
H7F25_13770	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F25_13780	COG1309	transcriptional regulator
H7F25_13785	COG0719	Fe-S assembly protein
H7F25_13790	COG0822	iron-sulfur transferase activity
H7F25_13795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7F25_13800	COG0719	Fe-S assembly protein
H7F25_13805	COG0396	ATPase activity
H7F25_13810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F25_13815	COG1464	Belongs to the NlpA lipoprotein family
H7F25_13820	COG2011	ABC-type metal ion transport system permease component
H7F25_13825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7F25_13835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F25_13840	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H7F25_13850	COG0509	glycine decarboxylation via glycine cleavage system
H7F25_13855	COG1393	Belongs to the ArsC family
H7F25_13860	COG1960	acyl-CoA dehydrogenase activity
H7F25_13865	COG0183	Belongs to the thiolase family
H7F25_13870	COG1024	Enoyl-CoA hydratase
H7F25_13870	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F25_13885	COG5577	PFAM Coat F domain
H7F25_13895	COG1120	ATPase activity
H7F25_13905	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_13910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F25_13915	COG0745	RESPONSE REGULATOR receiver
H7F25_13920	COG2770	Histidine kinase
H7F25_13920	COG2205	protein histidine kinase activity
H7F25_13930	COG1309	transcriptional regulator
H7F25_13940	COG0114	fumarate hydratase activity
H7F25_13950	COG0697	spore germination
H7F25_13955	COG0814	amino acid
H7F25_13970	COG2197	response regulator
H7F25_13975	COG4585	Histidine kinase
H7F25_13980	COG4758	membrane
H7F25_13990	COG1842	Phage shock protein A
H7F25_13995	COG4758	membrane
H7F25_14000	COG2096	Adenosyltransferase
H7F25_14005	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_14010	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7F25_14020	COG2204	response regulator
H7F25_14035	COG1454	alcohol dehydrogenase
H7F25_14040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F25_14050	COG1120	ATPase activity
H7F25_14055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F25_14060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F25_14070	COG2721	sulfolactate sulfo-lyase activity
H7F25_14075	COG0246	Mannitol dehydrogenase
H7F25_14080	COG1609	Transcriptional regulator
H7F25_14085	COG1904	glucuronate isomerase
H7F25_14090	COG2205	protein histidine kinase activity
H7F25_14095	COG0745	RESPONSE REGULATOR receiver
H7F25_14100	COG1120	ATPase activity
H7F25_14105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F25_14110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F25_14115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F25_14120	COG0531	amino acid
H7F25_14135	COG1988	membrane-bound metal-dependent
H7F25_14140	COG1368	sulfuric ester hydrolase activity
H7F25_14145	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7F25_14150	COG4149	molybdate abc transporter
H7F25_14155	COG0656	L-ascorbic acid biosynthetic process
H7F25_14160	COG1940	carbohydrate kinase activity
H7F25_14165	COG0025	NhaP-type Na H and K H
H7F25_14170	COG2860	membrane
H7F25_14175	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H7F25_14180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7F25_14185	COG2217	Heavy metal translocating P-type atpase
H7F25_14190	COG1121	(ABC) transporter
H7F25_14195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F25_14200	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7F25_14210	COG3226	Transcriptional regulator
H7F25_14215	COG0784	Response regulator, receiver
H7F25_14220	COG4191	Histidine kinase
H7F25_14225	COG1027	Aspartate ammonia-lyase
H7F25_14235	COG2217	Heavy metal translocating P-type atpase
H7F25_14240	COG2608	mercury ion transmembrane transporter activity
H7F25_14245	COG1937	Protein conserved in bacteria
H7F25_14295	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H7F25_14300	COG0557	exoribonuclease II activity
H7F25_14305	COG1647	Serine aminopeptidase, S33
H7F25_14310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7F25_14315	COG2002	toxin-antitoxin pair type II binding
H7F25_14320	COG1476	TRANSCRIPTIONal
H7F25_14325	COG1396	sequence-specific DNA binding
H7F25_14330	COG1396	sequence-specific DNA binding
H7F25_14335	COG1733	regulation of RNA biosynthetic process
H7F25_14340	COG1174	glycine betaine transport
H7F25_14345	COG1732	Glycine betaine
H7F25_14350	COG1174	glycine betaine transport
H7F25_14355	COG1125	glycine betaine transport
H7F25_14355	COG0517	IMP dehydrogenase activity
H7F25_14360	COG1510	regulation of RNA biosynthetic process
H7F25_14365	COG2095	MarC family integral membrane protein
H7F25_14375	COG0456	acetyltransferase
H7F25_14395	COG1122	ATPase activity
H7F25_14405	COG0148	phosphopyruvate hydratase activity
H7F25_14410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H7F25_14415	COG0149	triose-phosphate isomerase activity
H7F25_14420	COG0126	phosphoglycerate kinase activity
H7F25_14425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F25_14430	COG2390	Transcriptional regulator
H7F25_14435	COG0833	amino acid
H7F25_14440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F25_14445	COG3829	transcription factor binding
H7F25_14450	COG2186	Transcriptional regulator
H7F25_14455	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H7F25_14465	COG0534	Mate efflux family protein
H7F25_14475	COG0444	Belongs to the ABC transporter superfamily
H7F25_14480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F25_14485	COG0601	transmembrane transport
H7F25_14490	COG0747	negative chemotaxis
H7F25_14495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F25_14500	COG0110	maltose O-acetyltransferase activity
H7F25_14505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7F25_14510	COG2244	polysaccharide biosynthetic process
H7F25_14515	COG5039	Polysaccharide pyruvyl transferase
H7F25_14520	COG1216	Glycosyl transferase, family 2
H7F25_14530	COG0438	transferase activity, transferring glycosyl groups
H7F25_14535	COG1215	transferase activity, transferring glycosyl groups
H7F25_14540	COG0438	transferase activity, transferring glycosyl groups
H7F25_14545	COG1086	Polysaccharide biosynthesis protein
H7F25_14550	COG0489	protein tyrosine kinase activity
H7F25_14555	COG3944	biosynthesis protein
H7F25_14560	COG1396	sequence-specific DNA binding
H7F25_14570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F25_14575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F25_14580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F25_14585	COG0726	polysaccharide deacetylase
H7F25_14590	COG0488	(ABC) transporter
H7F25_14610	COG0601	transmembrane transport
H7F25_14615	COG0747	negative chemotaxis
H7F25_14620	COG1819	glycosyl
H7F25_14635	COG0740	serine-type endopeptidase activity
H7F25_14640	COG1611	Belongs to the LOG family
H7F25_14645	COG1694	Mazg nucleotide pyrophosphohydrolase
H7F25_14650	COG0659	secondary active sulfate transmembrane transporter activity
H7F25_14655	COG0288	reversible hydration of carbon dioxide
H7F25_14660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F25_14670	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H7F25_14675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F25_14680	COG1481	regulation of sporulation
H7F25_14685	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H7F25_14690	COG1660	Displays ATPase and GTPase activities
H7F25_14695	COG1051	belongs to the nudix hydrolase family
H7F25_14700	COG0492	ferredoxin-NADP+ reductase activity
H7F25_14705	COG0791	NLP P60 protein
H7F25_14705	COG3883	PFAM NLP P60 protein
H7F25_14710	COG0457	Tetratricopeptide repeat
H7F25_14715	COG0140	phosphoribosyl-ATP diphosphatase activity
H7F25_14715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7F25_14720	COG0107	imidazoleglycerol-phosphate synthase activity
H7F25_14725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H7F25_14730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H7F25_14735	COG0131	Imidazoleglycerol-phosphate dehydratase
H7F25_14740	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H7F25_14745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7F25_14750	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H7F25_14755	COG4990	cell redox homeostasis
H7F25_14765	COG2910	NAD(P)H-binding
H7F25_14770	COG1959	2 iron, 2 sulfur cluster binding
H7F25_14775	COG0110	maltose O-acetyltransferase activity
H7F25_14780	COG0546	phosphoglycolate phosphatase activity
H7F25_14785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H7F25_14795	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H7F25_14800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H7F25_14805	COG0363	glucosamine-6-phosphate deaminase activity
H7F25_14810	COG2188	Transcriptional regulator
H7F25_14815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7F25_14820	COG1950	PFAM Membrane protein of
H7F25_14825	COG1983	PspC domain protein
H7F25_14830	COG3595	metallopeptidase activity
H7F25_14845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H7F25_14855	COG4897	Protein conserved in bacteria
H7F25_14860	COG3848	Pyruvate phosphate dikinase
H7F25_14860	COG0574	Belongs to the PEP-utilizing enzyme family
H7F25_14865	COG1309	transcriptional regulator
H7F25_14870	COG2814	Major facilitator Superfamily
H7F25_14880	COG0745	RESPONSE REGULATOR receiver
H7F25_14885	COG5002	protein histidine kinase activity
H7F25_14890	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7F25_14895	COG0463	Glycosyl transferase, family 2
H7F25_14900	COG1113	amino acid transport
H7F25_14905	COG0778	Nitroreductase
H7F25_14910	COG1733	regulation of RNA biosynthetic process
H7F25_14915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F25_14925	COG3409	Peptidoglycan-binding domain 1 protein
H7F25_14925	COG0793	Belongs to the peptidase S41A family
H7F25_14930	COG0730	response to heat
H7F25_14935	COG0791	NLP P60 protein
H7F25_14935	COG3883	PFAM NLP P60 protein
H7F25_14940	COG2177	Part of the ABC transporter FtsEX involved in
H7F25_14945	COG2884	Cell division ATP-binding protein ftsE
H7F25_14950	COG2010	Cytochrome c
H7F25_14955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F25_14975	COG0653	protein targeting
H7F25_14980	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H7F25_14985	COG0840	transmembrane signaling receptor activity
H7F25_15000	COG1516	flagellar protein fliS
H7F25_15005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H7F25_15010	COG1334	flagellar protein FlaG
H7F25_15015	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H7F25_15020	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
H7F25_15030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F25_15035	COG1256	bacterial-type flagellum assembly
H7F25_15035	COG4786	Flagellar basal body rod
H7F25_15040	COG3418	PFAM FlgN family protein
H7F25_15055	COG1040	competence protein
H7F25_15065	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H7F25_15070	COG1307	EDD domain protein, DegV family
H7F25_15075	COG2197	response regulator
H7F25_15080	COG4585	Histidine kinase
H7F25_15085	COG1739	Uncharacterized protein family UPF0029
H7F25_15090	COG1316	TRANSCRIPTIONal
H7F25_15095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F25_15100	COG0438	transferase activity, transferring glycosyl groups
H7F25_15105	COG1215	transferase activity, transferring glycosyl groups
H7F25_15110	COG3206	protein involved in exopolysaccharide biosynthesis
H7F25_15115	COG3307	-O-antigen
H7F25_15120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F25_15125	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H7F25_15130	COG0438	transferase activity, transferring glycosyl groups
H7F25_15130	COG0297	glycogen (starch) synthase activity
H7F25_15135	COG2244	polysaccharide biosynthetic process
H7F25_15150	COG2247	cell wall binding repeat
H7F25_15150	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F25_15155	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F25_15155	COG2247	cell wall binding repeat
H7F25_15160	COG2385	sporulation resulting in formation of a cellular spore
H7F25_15160	COG2247	cell wall binding repeat
H7F25_15170	COG1316	TRANSCRIPTIONal
H7F25_15175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H7F25_15180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7F25_15185	COG1134	teichoic acid transport
H7F25_15190	COG1682	transport, permease protein
H7F25_15200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F25_15210	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H7F25_15215	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H7F25_15220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F25_15225	COG4193	domain, Protein
H7F25_15230	COG1482	cell wall glycoprotein biosynthetic process
H7F25_15240	COG1175	transmembrane transport
H7F25_15245	COG1653	transport
H7F25_15250	COG2201	protein-glutamate methylesterase activity
H7F25_15255	COG2972	Histidine kinase
H7F25_15265	COG0454	-acetyltransferase
H7F25_15270	COG0800	Aldolase
H7F25_15275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F25_15280	COG1609	Transcriptional regulator
H7F25_15285	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H7F25_15290	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_15295	COG0697	spore germination
H7F25_15300	COG0814	amino acid
H7F25_15315	COG2814	Major facilitator Superfamily
H7F25_15320	COG1316	TRANSCRIPTIONal
H7F25_15325	COG0561	phosphatase activity
H7F25_15330	COG0791	NLP P60 protein
H7F25_15340	COG2843	Capsule synthesis protein
H7F25_15350	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F25_15355	COG0697	spore germination
H7F25_15370	COG1609	Transcriptional regulator
H7F25_15375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F25_15380	COG1869	D-ribose catabolic process
H7F25_15385	COG1129	ABC transporter
H7F25_15390	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F25_15395	COG1879	ABC-type sugar transport system periplasmic component
H7F25_15400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F25_15405	COG0583	DNA-binding transcription factor activity
H7F25_15410	COG0028	Belongs to the TPP enzyme family
H7F25_15415	COG3527	Alpha-acetolactate decarboxylase
H7F25_15420	COG1522	sequence-specific DNA binding
H7F25_15425	COG2059	Chromate
H7F25_15430	COG2059	Chromate
H7F25_15435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H7F25_15445	COG4715	Zinc finger, swim domain protein
H7F25_15450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7F25_15455	COG2202	Pas domain
H7F25_15455	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F25_15460	COG0561	phosphatase activity
H7F25_15475	COG1970	mechanosensitive ion channel activity
H7F25_15480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F25_15485	COG0457	Tetratricopeptide repeat
H7F25_15490	COG4786	Flagellar basal body rod
H7F25_15495	COG4786	Flagellar basal body rod
H7F25_15500	COG1077	Cell shape determining protein MreB Mrl
H7F25_15505	COG1609	Transcriptional regulator
H7F25_15510	COG1846	Transcriptional regulator
H7F25_15515	COG2814	Major facilitator Superfamily
H7F25_15520	COG0671	phosphoesterase, PA-phosphatase related
H7F25_15525	COG0477	Major facilitator Superfamily
H7F25_15530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F25_15535	COG0765	amino acid transport
H7F25_15545	COG0004	ammonium transporteR
H7F25_15550	COG0347	Belongs to the P(II) protein family
H7F25_15555	COG0739	heme binding
H7F25_15560	COG1247	-acetyltransferase
H7F25_15600	COG0523	cobalamin synthesis protein
H7F25_15605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F25_15610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7F25_15615	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7F25_15620	COG2223	nitrite transmembrane transporter activity
H7F25_15625	COG0243	molybdopterin cofactor binding
H7F25_15630	COG2304	oxidoreductase activity
H7F25_15635	COG2304	oxidoreductase activity
H7F25_15640	COG2385	sporulation resulting in formation of a cellular spore
H7F25_15645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F25_15655	COG4836	Membrane
H7F25_15665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H7F25_15670	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H7F25_15675	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H7F25_15680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H7F25_15685	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F25_15690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H7F25_15695	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F25_15700	COG0356	it plays a direct role in the translocation of protons across the membrane
H7F25_15710	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H7F25_15715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H7F25_15720	COG4475	Protein of unknown function (DUF436)
H7F25_15725	COG0698	ribose 5-phosphate isomerase
H7F25_15730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F25_15735	COG1971	Probably functions as a manganese efflux pump
H7F25_15740	COG0009	L-threonylcarbamoyladenylate synthase
H7F25_15745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H7F25_15760	COG2890	protein-(glutamine-N5) methyltransferase activity
H7F25_15765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H7F25_15770	COG0789	Transcriptional regulator
H7F25_15775	COG0679	Auxin Efflux Carrier
H7F25_15780	COG0281	malic enzyme
H7F25_15785	COG1435	thymidine kinase activity
H7F25_15790	COG0254	rRNA binding
H7F25_15795	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H7F25_15800	COG1494	fructose-1,6-bisphosphatase
H7F25_15805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F25_15810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7F25_15815	COG0191	fructose-bisphosphate aldolase activity
H7F25_15820	COG2204	response regulator
H7F25_15825	COG4821	SIS domain
H7F25_15830	COG0504	CTP synthase activity
H7F25_15835	COG3343	RNA polymerase activity
H7F25_15845	COG1960	acyl-CoA dehydrogenase activity
H7F25_15850	COG1960	acyl-CoA dehydrogenase activity
H7F25_15855	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F25_15860	COG0183	Belongs to the thiolase family
H7F25_15865	COG2181	nitrate reductase activity
H7F25_15865	COG0247	lactate metabolic process
H7F25_15870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F25_15875	COG4294	response to UV
H7F25_15885	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F25_15890	COG1132	(ABC) transporter
H7F25_15895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F25_15900	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F25_15905	COG0018	arginyl-trna synthetase
H7F25_15910	COG4506	Protein conserved in bacteria
H7F25_15920	COG0010	Belongs to the arginase family
H7F25_15925	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H7F25_15930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F25_15940	COG1994	Peptidase M50
H7F25_15945	COG1942	4-Oxalocrotonate Tautomerase
H7F25_15955	COG3465	dGTPase activity
H7F25_15960	COG1078	dGTPase activity
H7F25_15965	COG4844	belongs to the
H7F25_16015	COG5444	nuclease activity
H7F25_16045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7F25_16055	COG0280	phosphate acetyltransferase
H7F25_16065	COG2814	Major facilitator Superfamily
H7F25_16070	COG1522	sequence-specific DNA binding
H7F25_16075	COG2814	Major facilitator Superfamily
H7F25_16080	COG0077	Prephenate dehydratase
H7F25_16090	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_16095	COG0151	Belongs to the GarS family
H7F25_16100	COG0436	Aminotransferase
H7F25_16105	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_16110	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
H7F25_16115	COG1091	dTDP-4-dehydrorhamnose reductase activity
H7F25_16120	COG1088	dTDP-glucose 4,6-dehydratase activity
H7F25_16125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H7F25_16130	COG3980	spore coat polysaccharide biosynthesis protein
H7F25_16135	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
H7F25_16140	COG2089	acid synthase
H7F25_16145	COG0456	acetyltransferase
H7F25_16150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F25_16155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F25_16160	COG0463	Glycosyl transferase, family 2
H7F25_16180	COG2363	Small membrane protein
H7F25_16185	COG2233	PERMEase
H7F25_16195	COG1012	belongs to the aldehyde dehydrogenase family
H7F25_16200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H7F25_16205	COG1216	Glycosyl transferase, family 2
H7F25_16215	COG0351	phosphomethylpyrimidine kinase
H7F25_16235	COG3964	amidohydrolase
H7F25_16240	COG1621	beta-fructofuranosidase activity
H7F25_16245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F25_16245	COG1263	PTS System
H7F25_16250	COG3711	transcriptional antiterminator
H7F25_16260	COG1404	Belongs to the peptidase S8 family
H7F25_16265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F25_16270	COG0778	Nitroreductase
H7F25_16275	COG0772	Belongs to the SEDS family
H7F25_16285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F25_16290	COG1845	cytochrome c oxidase, subunit III
H7F25_16295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F25_16300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F25_16310	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H7F25_16315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F25_16320	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H7F25_16335	COG2246	polysaccharide biosynthetic process
H7F25_16355	COG3162	membrane
H7F25_16360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F25_16370	COG0352	thiamine-phosphate diphosphorylase activity
H7F25_16375	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H7F25_16380	COG0583	DNA-binding transcription factor activity
H7F25_16385	COG1380	Effector of murein hydrolase LrgA
H7F25_16390	COG1346	cytolysis
H7F25_16395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H7F25_16400	COG0346	lactoylglutathione lyase activity
H7F25_16410	COG0765	amino acid transport
H7F25_16415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F25_16420	COG0457	Tetratricopeptide repeat
H7F25_16430	COG2357	RelA SpoT domain protein
H7F25_16435	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F25_16440	COG1129	ABC transporter
H7F25_16450	COG3420	alginic acid biosynthetic process
H7F25_16455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F25_16465	COG1486	melibiose metabolic process
H7F25_16470	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F25_16475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F25_16480	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F25_16485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F25_16485	COG3711	transcriptional antiterminator
H7F25_16500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F25_16515	COG1595	DNA-templated transcription, initiation
H7F25_16525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H7F25_16530	COG4988	ABC transporter
H7F25_16535	COG1294	oxidase, subunit
H7F25_16540	COG1271	oxidase subunit
H7F25_16560	COG4509	Sortase family
H7F25_16585	COG5386	Cell surface protein
H7F25_16590	COG5386	Cell surface protein
H7F25_16595	COG1733	regulation of RNA biosynthetic process
H7F25_16600	COG2514	catechol 2,3-dioxygenase activity
H7F25_16605	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F25_16605	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F25_16610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F25_16610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F25_16620	COG0726	polysaccharide deacetylase
H7F25_16625	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F25_16630	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F25_16635	COG2723	6-phospho-beta-galactosidase activity
H7F25_16640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F25_16645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F25_16645	COG3711	transcriptional antiterminator
H7F25_16670	COG1757	Na H antiporter
H7F25_16675	COG1027	Aspartate ammonia-lyase
H7F25_16680	COG0252	asparaginase activity
H7F25_16685	COG1396	sequence-specific DNA binding
H7F25_16710	COG4842	Belongs to the WXG100 family
H7F25_16715	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7F25_16730	COG1737	Transcriptional regulator
H7F25_16735	COG2084	Dehydrogenase
H7F25_16745	COG2610	gluconate transmembrane transporter activity
H7F25_16750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F25_16760	COG2723	6-phospho-beta-galactosidase activity
H7F25_16765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F25_16765	COG1263	PTS System
H7F25_16765	COG2190	(PTS) system
H7F25_16770	COG3711	transcriptional antiterminator
H7F25_16775	COG3878	Protein conserved in bacteria
H7F25_16785	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F25_16790	COG1122	ATPase activity
H7F25_16795	COG4721	ABC-type cobalt transport system, permease component
H7F25_16800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7F25_16835	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7F25_16840	COG0778	Nitroreductase
H7F25_16845	COG1846	Transcriptional regulator
H7F25_16850	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H7F25_16855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F25_16860	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H7F25_16865	COG2390	Transcriptional regulator
H7F25_16875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F25_16875	COG2755	lipolytic protein G-D-S-L family
H7F25_16895	COG0561	phosphatase activity
H7F25_16900	COG0789	Transcriptional regulator
H7F25_16905	COG0673	inositol 2-dehydrogenase activity
H7F25_16910	COG0840	transmembrane signaling receptor activity
H7F25_16915	COG1113	amino acid transport
H7F25_16920	COG4335	DNA alkylation repair
H7F25_16930	COG1070	Carbohydrate kinase
H7F25_16935	COG1737	Transcriptional regulator
H7F25_16965	COG0583	DNA-binding transcription factor activity
H7F25_16970	COG1609	Transcriptional regulator
H7F25_16975	COG2182	Extracellular solute-binding protein
H7F25_16980	COG1175	transmembrane transport
H7F25_16985	COG3833	ABC-type maltose transport systems, permease component
H7F25_16995	COG1874	Beta-galactosidase
H7F25_17000	COG2851	Citrate transporter
H7F25_17010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F25_17015	COG1131	(ABC) transporter
H7F25_17020	COG2824	Alkylphosphonate utilization operon protein PhnA
H7F25_17025	COG1929	Belongs to the glycerate kinase type-1 family
H7F25_17030	COG2610	gluconate transmembrane transporter activity
H7F25_17035	COG3835	regulator
H7F25_17040	COG1309	transcriptional regulator
H7F25_17045	COG2814	Major facilitator Superfamily
H7F25_17055	COG1136	(ABC) transporter
H7F25_17055	COG0577	efflux transmembrane transporter activity
H7F25_17065	COG0457	Tetratricopeptide repeat
H7F25_17070	COG3711	transcriptional antiterminator
H7F25_17075	COG2723	6-phospho-beta-galactosidase activity
H7F25_17080	COG1263	PTS System
H7F25_17080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F25_17080	COG2190	(PTS) system
H7F25_17115	COG1113	amino acid transport
H7F25_17120	COG1609	Transcriptional regulator
H7F25_17125	COG2814	Major facilitator Superfamily
H7F25_17135	COG2814	Major facilitator Superfamily
H7F25_17155	COG5444	nuclease activity
H7F25_17165	COG2723	6-phospho-beta-galactosidase activity
H7F25_17175	COG2188	Transcriptional regulator
H7F25_17185	COG0384	phenazine biosynthesis protein PhzF
H7F25_17190	COG0583	DNA-binding transcription factor activity
H7F25_17215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F25_17225	COG2814	Major facilitator Superfamily
H7F25_17230	COG0640	Transcriptional regulator
H7F25_17250	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H7F25_17260	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F25_17270	COG4720	Psort location CytoplasmicMembrane, score
H7F25_17290	COG0456	acetyltransferase
H7F25_17295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F25_17300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H7F25_17305	COG4853	Protein conserved in bacteria
H7F25_17310	COG4863	YycH protein
H7F25_17315	COG5002	protein histidine kinase activity
H7F25_17320	COG0745	RESPONSE REGULATOR receiver
H7F25_17345	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7F25_17355	COG2311	Membrane
H7F25_17360	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H7F25_17365	COG0346	lactoylglutathione lyase activity
H7F25_17370	COG0305	Participates in initiation and elongation during chromosome replication
H7F25_17395	COG2819	hydrolase of the alpha beta superfamily
H7F25_17400	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_17405	COG1169	isochorismate synthase
H7F25_17410	COG1021	2,3-dihydroxybenzoate-AMP ligase
H7F25_17415	COG1535	isochorismatase
H7F25_17415	COG3433	isochorismatase activity
H7F25_17420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F25_17425	COG3251	PFAM MbtH domain protein
H7F25_17430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F25_17430	COG2207	Transcriptional regulator
H7F25_17435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F25_17440	COG2819	hydrolase of the alpha beta superfamily
H7F25_17445	COG3093	addiction module antidote protein HigA
H7F25_17450	COG2807	transmembrane transport
H7F25_17455	COG0359	binds to the 23S rRNA
H7F25_17460	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H7F25_17465	COG4241	membrane
H7F25_17470	COG1227	inorganic diphosphatase activity
H7F25_17480	COG1595	DNA-templated transcription, initiation
H7F25_17490	COG0753	catalase activity
H7F25_17495	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7F25_17500	COG0400	carboxylic ester hydrolase activity
H7F25_17505	COG0346	lactoylglutathione lyase activity
H7F25_17510	COG1174	glycine betaine transport
H7F25_17515	COG0517	IMP dehydrogenase activity
H7F25_17515	COG1125	glycine betaine transport
H7F25_17520	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H7F25_17525	COG0629	single-stranded DNA binding
H7F25_17530	COG0360	Binds together with S18 to 16S ribosomal RNA
H7F25_17535	COG0012	GTP binding
H7F25_17540	COG4481	Protein conserved in bacteria
H7F25_17555	COG3949	Membrane
H7F25_17565	COG1475	DNA binding
H7F25_17570	COG1192	Involved in chromosome partitioning
H7F25_17580	COG1475	DNA binding
H7F25_17585	COG0357	Ribosomal RNA small subunit methyltransferase G
H7F25_17590	COG0445	tRNA wobble uridine modification
H7F25_17595	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H7F25_17600	COG1847	R3H domain protein
H7F25_17605	COG0706	membrane insertase activity
H7F25_17610	COG0594	ribonuclease P activity
H7F25_17615	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H7F25_17620	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7F25_17625	COG0592	DNA-directed DNA polymerase activity
H7F25_17630	COG2501	S4 domain
H7F25_17635	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7F25_17645	COG0187	DNA topoisomerase II activity
H7F25_17650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7F25_17685	COG0516	GMP reductase activity
H7F25_17685	COG0517	IMP dehydrogenase activity
H7F25_17690	COG1686	Belongs to the peptidase S11 family
H7F25_17695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F25_17700	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
H7F25_17705	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
H7F25_17710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H7F25_17715	COG0840	transmembrane signaling receptor activity
H7F25_17725	COG1428	Deoxynucleoside kinase
H7F25_17730	COG1428	Deoxynucleoside kinase
H7F25_17735	COG3858	chitin binding
H7F25_17735	COG1388	LysM domain
H7F25_17740	COG1335	isochorismatase
H7F25_17745	COG0590	tRNA wobble adenosine to inosine editing
H7F25_17755	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7F25_17760	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H7F25_17765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7F25_17810	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
H7F25_17815	COG3853	Toxic anion resistance protein (TelA)
H7F25_17820	COG1982	Orn Lys Arg decarboxylase major
H7F25_17825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H7F25_17830	COG3870	Protein conserved in bacteria
H7F25_17835	COG1728	Protein conserved in bacteria
H7F25_17840	COG0470	DNA polymerase III
H7F25_17845	COG1774	PSP1 C-terminal conserved region
H7F25_17850	COG4467	Involved in initiation control of chromosome replication
H7F25_17855	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H7F25_17860	COG2827	Endonuclease containing a URI domain
H7F25_17865	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7F25_17870	COG2002	toxin-antitoxin pair type II binding
H7F25_17875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F25_17875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F25_17880	COG0084	hydrolase, TatD family'
H7F25_17885	COG3583	domain protein
H7F25_17885	COG3584	3D domain protein
H7F25_17890	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H7F25_17895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7F25_17905	COG4466	Protein conserved in bacteria
H7F25_17915	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H7F25_17920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F25_17925	COG0251	oxidation-reduction process
H7F25_17930	COG2088	sporulation resulting in formation of a cellular spore
H7F25_17940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7F25_17945	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H7F25_17950	COG0193	aminoacyl-tRNA hydrolase activity
H7F25_17960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7F25_17965	COG2002	toxin-antitoxin pair type II binding
H7F25_17970	COG2244	polysaccharide biosynthetic process
H7F25_17975	COG3956	TIGRFAM MazG family protein
H7F25_17980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H7F25_17995	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7F25_18000	COG1098	S1 RNA binding domain
H7F25_18015	COG2208	phosphoserine phosphatase activity
H7F25_18020	COG2304	oxidoreductase activity
H7F25_18025	COG0515	serine threonine protein kinase
H7F25_18030	COG0037	tRNA processing
H7F25_18035	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H7F25_18040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F25_18045	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H7F25_18050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7F25_18055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F25_18060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F25_18065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7F25_18070	COG0512	Glutamine amidotransferase of anthranilate synthase
H7F25_18075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F25_18080	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7F25_18085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H7F25_18090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7F25_18095	COG1396	sequence-specific DNA binding
H7F25_18100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F25_18105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H7F25_18185	COG4463	regulation of RNA biosynthetic process
H7F25_18190	COG3880	PFAM UvrB UvrC protein
H7F25_18195	COG3869	Catalyzes the specific phosphorylation of arginine residues in
H7F25_18200	COG0542	response to heat
H7F25_18205	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H7F25_18210	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
H7F25_18215	COG4956	integral membrane protein (PIN domain superfamily)
H7F25_18220	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H7F25_18225	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H7F25_18230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F25_18235	COG1045	serine acetyltransferase
H7F25_18240	COG0215	cysteine-tRNA ligase activity
H7F25_18245	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H7F25_18250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F25_18255	COG3688	RNA-binding protein containing a PIN domain
H7F25_18260	COG1595	DNA-templated transcription, initiation
H7F25_18265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F25_18270	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7F25_18275	COG0250	Participates in transcription elongation, termination and antitermination
H7F25_18285	COG0081	regulation of translation
H7F25_18290	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H7F25_18295	COG0222	ribosome binding
H7F25_18300	COG2813	Specifically methylates the guanine in position
H7F25_18305	COG0085	RNA polymerase activity
H7F25_18310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H7F25_18315	COG1358	cellular component organization or biogenesis
H7F25_18320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H7F25_18325	COG0049	tRNA binding
H7F25_18330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7F25_18335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7F25_18340	COG0596	Alpha beta hydrolase
H7F25_18350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H7F25_18355	COG0088	Forms part of the polypeptide exit tunnel
H7F25_18360	COG0089	rRNA binding
H7F25_18365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H7F25_18370	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H7F25_18375	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H7F25_18380	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H7F25_18390	COG0255	Belongs to the universal ribosomal protein uL29 family
H7F25_18395	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H7F25_18400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H7F25_18405	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H7F25_18410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H7F25_18415	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F25_18420	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H7F25_18425	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H7F25_18430	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H7F25_18435	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H7F25_18440	COG1841	ribosomal large subunit assembly
H7F25_18445	COG0200	Binds to the 23S rRNA
H7F25_18450	COG0201	protein transport
H7F25_18455	COG0563	adenylate kinase activity
H7F25_18460	COG0024	Methionine aminopeptidase
H7F25_18465	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H7F25_18470	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7F25_18475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H7F25_18480	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H7F25_18485	COG0202	RNA polymerase activity
H7F25_18490	COG0203	ribosomal protein L17
H7F25_18495	COG1122	ATPase activity
H7F25_18500	COG1122	ATPase activity
H7F25_18505	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F25_18510	COG0101	tRNA pseudouridine synthase activity
H7F25_18515	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H7F25_18520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H7F25_18525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F25_18550	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F25_18555	COG0489	protein tyrosine kinase activity
H7F25_18565	COG2194	sulfuric ester hydrolase activity
H7F25_18570	COG0726	polysaccharide deacetylase
H7F25_18600	COG0659	secondary active sulfate transmembrane transporter activity
H7F25_18605	COG0385	Bile acid
H7F25_18610	COG3876	Protein conserved in bacteria
H7F25_18615	COG1472	Belongs to the glycosyl hydrolase 3 family
H7F25_18620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F25_18625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F25_18625	COG1263	PTS System
H7F25_18630	COG1737	Transcriptional regulator
H7F25_18635	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H7F25_18670	COG1595	DNA-templated transcription, initiation
H7F25_18675	COG5662	AntiSigma factor
H7F25_18680	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H7F25_18685	COG4856	YbbR-like protein
H7F25_18690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F25_18695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7F25_18715	COG1131	(ABC) transporter
H7F25_18730	COG1131	(ABC) transporter
H7F25_18740	COG1413	lyase activity
H7F25_18750	COG2311	Membrane
H7F25_18770	COG1113	amino acid transport
H7F25_18775	COG0584	glycerophosphoryl diester phosphodiesterase
H7F25_18780	COG2271	Major facilitator Superfamily
H7F25_18790	COG1331	Highly conserved protein containing a thioredoxin domain
H7F25_18795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F25_18815	COG1937	Protein conserved in bacteria
H7F25_18820	COG2210	Belongs to the sulfur carrier protein TusA family
H7F25_18830	COG0425	Belongs to the sulfur carrier protein TusA family
H7F25_18830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F25_18835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F25_18835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F25_18840	COG0425	Belongs to the sulfur carrier protein TusA family
H7F25_18845	COG0730	response to heat
H7F25_18855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F25_18860	COG2814	Major facilitator Superfamily
H7F25_18870	COG1846	Transcriptional regulator
H7F25_18880	COG1683	Conserved Protein
H7F25_18890	COG0656	L-ascorbic acid biosynthetic process
H7F25_18895	COG1054	Belongs to the UPF0176 family
H7F25_18900	COG0531	amino acid
H7F25_18910	COG3711	transcriptional antiterminator
H7F25_18915	COG1263	PTS System
H7F25_18915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F25_18915	COG2190	(PTS) system
H7F25_18920	COG2723	6-phospho-beta-galactosidase activity
H7F25_18940	COG3711	transcriptional antiterminator
H7F25_18940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F25_18945	COG1940	carbohydrate kinase activity
H7F25_18950	COG0383	alpha-mannosidase activity
H7F25_18955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F25_18960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F25_18970	COG1404	Belongs to the peptidase S8 family
H7F25_18985	COG0833	amino acid
H7F25_18990	COG2040	homocysteine
H7F25_18995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F25_19000	COG1695	Transcriptional regulator
H7F25_19015	COG2814	Major facilitator Superfamily
H7F25_19020	COG0456	acetyltransferase
H7F25_19035	COG1404	Belongs to the peptidase S8 family
H7F25_19045	COG1309	transcriptional regulator
H7F25_19050	COG1917	Cupin 2, conserved barrel domain protein
H7F25_19055	COG1063	alcohol dehydrogenase
H7F25_19060	COG1846	Transcriptional regulator
H7F25_19065	COG0318	PFAM AMP-dependent synthetase and ligase
H7F25_19070	COG0531	amino acid
H7F25_19080	COG0596	Alpha beta hydrolase
H7F25_19085	COG1115	amino acid carrier protein
H7F25_19090	COG2066	Belongs to the glutaminase family
H7F25_19095	COG4191	Histidine kinase
H7F25_19100	COG0784	Response regulator, receiver
H7F25_19105	COG1405	negative regulation of cell septum assembly
H7F25_19105	COG3012	SEC-C Motif Domain Protein
H7F25_19115	COG2197	response regulator
H7F25_19120	COG4585	Histidine kinase
H7F25_19130	COG0667	Aldo Keto reductase
H7F25_19135	COG3290	protein histidine kinase activity
H7F25_19140	COG3279	Response regulator of the LytR AlgR family
H7F25_19145	COG4555	ABC transporter
H7F25_19150	COG1668	transmembrane transport
H7F25_19165	COG3773	Cell wall hydrolase
H7F25_19170	COG1028	Short-chain dehydrogenase reductase Sdr
H7F25_19180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F25_19185	COG2310	stress, protein
H7F25_19190	COG2310	stress, protein
H7F25_19195	COG2310	stress, protein
H7F25_19200	COG0861	Integral membrane protein TerC family
H7F25_19230	COG3853	Toxic anion resistance protein (TelA)
H7F25_19235	COG0517	IMP dehydrogenase activity
H7F25_19235	COG4175	Glycine betaine
H7F25_19240	COG4176	ABC-type proline glycine betaine transport system permease component