locus-tag	class	description
H7F26_00005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F26_00025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F26_00035	COG0301	tRNA thio-modification
H7F26_00040	COG1104	cysteine desulfurase activity
H7F26_00045	COG1114	Component of the transport system for branched-chain amino acids
H7F26_00055	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
H7F26_00060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7F26_00065	COG1309	transcriptional regulator
H7F26_00070	COG1956	GAF domain-containing protein
H7F26_00075	COG2203	Gaf domain
H7F26_00075	COG2199	diguanylate cyclase activity
H7F26_00080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H7F26_00090	COG3152	Membrane
H7F26_00095	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F26_00100	COG1522	sequence-specific DNA binding
H7F26_00110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7F26_00115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F26_00120	COG0454	-acetyltransferase
H7F26_00125	COG0517	IMP dehydrogenase activity
H7F26_00130	COG0123	including yeast histone deacetylase and acetoin utilization protein
H7F26_00135	COG1360	Flagellar Motor Protein
H7F26_00140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7F26_00145	COG1609	Transcriptional regulator
H7F26_00150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H7F26_00150	COG1605	Chorismate mutase
H7F26_00160	COG3118	belongs to the thioredoxin family
H7F26_00165	COG4980	gas vesicle protein
H7F26_00170	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H7F26_00175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7F26_00180	COG1674	ftsk spoiiie
H7F26_00185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F26_00190	COG4848	Belongs to the UPF0354 family
H7F26_00195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_00205	COG1363	Peptidase, m42
H7F26_00210	COG5584	Small secreted protein
H7F26_00215	COG0281	malic enzyme
H7F26_00220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_00225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7F26_00235	COG0510	thiamine kinase activity
H7F26_00240	COG1523	belongs to the glycosyl hydrolase 13 family
H7F26_00245	COG1597	lipid kinase activity
H7F26_00255	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7F26_00260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F26_00275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F26_00280	COG2252	PERMEase
H7F26_00285	COG1349	DNA-binding transcription factor activity
H7F26_00290	COG1187	pseudouridine synthase activity
H7F26_00295	COG2244	polysaccharide biosynthetic process
H7F26_00300	COG2081	HI0933 family
H7F26_00305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7F26_00315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F26_00320	COG0457	Tetratricopeptide repeat
H7F26_00330	COG5578	integral membrane protein
H7F26_00335	COG0673	inositol 2-dehydrogenase activity
H7F26_00340	COG1653	transport
H7F26_00345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H7F26_00350	COG4209	transmembrane transport
H7F26_00355	COG2207	Transcriptional regulator
H7F26_00360	COG1653	transport
H7F26_00365	COG0395	ABC-type sugar transport system, permease component
H7F26_00370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F26_00375	COG1073	alpha beta
H7F26_00385	COG0583	DNA-binding transcription factor activity
H7F26_00390	COG0346	lactoylglutathione lyase activity
H7F26_00395	COG0495	leucyl-tRNA aminoacylation
H7F26_00405	COG2814	Major facilitator Superfamily
H7F26_00415	COG2433	Pfam Transposase IS66
H7F26_00420	COG0577	efflux transmembrane transporter activity
H7F26_00425	COG1136	(ABC) transporter
H7F26_00435	COG1131	(ABC) transporter
H7F26_00440	COG1725	Transcriptional regulator
H7F26_00450	COG1242	4 iron, 4 sulfur cluster binding
H7F26_00455	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H7F26_00460	COG1301	dicarboxylic acid transport
H7F26_00470	COG2267	carboxylic ester hydrolase activity
H7F26_00475	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7F26_00485	COG0438	transferase activity, transferring glycosyl groups
H7F26_00485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F26_00490	COG0367	asparagine synthase
H7F26_00495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H7F26_00500	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H7F26_00505	COG1301	dicarboxylic acid transport
H7F26_00515	COG1506	peptidase
H7F26_00520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F26_00525	COG1116	anion transmembrane transporter activity
H7F26_00530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F26_00535	COG0494	nUDIX hydrolase
H7F26_00545	COG4824	toxin secretion phage lysis holin
H7F26_00550	COG0783	Belongs to the Dps family
H7F26_00565	COG1854	S-ribosylhomocysteine lyase activity
H7F26_00570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7F26_00575	COG0288	reversible hydration of carbon dioxide
H7F26_00580	COG0523	cobalamin synthesis protein
H7F26_00585	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7F26_00590	COG0254	rRNA binding
H7F26_00595	COG1271	oxidase subunit
H7F26_00600	COG1294	oxidase, subunit
H7F26_00615	COG4948	Mandelate Racemase Muconate Lactonizing
H7F26_00620	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_00625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H7F26_00630	COG0596	Alpha beta hydrolase
H7F26_00635	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H7F26_00640	COG1169	isochorismate synthase
H7F26_00645	COG1575	Belongs to the MenA family. Type 1 subfamily
H7F26_00650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F26_00665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H7F26_00670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H7F26_00675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H7F26_00795	COG1609	Transcriptional regulator
H7F26_00800	COG3859	Proton-coupled thiamine transporter YuaJ
H7F26_00805	COG3764	Sortase (surface protein transpeptidase)
H7F26_00820	COG0457	Tetratricopeptide repeat
H7F26_00825	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H7F26_00830	COG0569	domain protein
H7F26_00835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7F26_00845	COG2318	DinB family
H7F26_00855	COG1454	alcohol dehydrogenase
H7F26_00860	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_00865	COG1510	regulation of RNA biosynthetic process
H7F26_00875	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H7F26_00880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F26_00885	COG2140	Oxalate decarboxylase
H7F26_00920	COG1397	ADP-ribosylglycohydrolase
H7F26_00955	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
H7F26_00970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F26_00975	COG0726	polysaccharide deacetylase
H7F26_00980	COG1408	metallophosphoesterase
H7F26_00985	COG1968	undecaprenyl-diphosphatase activity
H7F26_00990	COG0628	permease
H7F26_00995	COG0673	inositol 2-dehydrogenase activity
H7F26_01000	COG0693	protein deglycase activity
H7F26_01005	COG0840	transmembrane signaling receptor activity
H7F26_01010	COG0840	transmembrane signaling receptor activity
H7F26_01025	COG2070	2-Nitropropane dioxygenase
H7F26_01030	COG0432	Pfam Uncharacterised protein family UPF0047
H7F26_01050	COG5297	Belongs to the glycosyl hydrolase family 6
H7F26_01055	COG1253	flavin adenine dinucleotide binding
H7F26_01060	COG2738	Putative neutral zinc metallopeptidase
H7F26_01070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7F26_01080	COG2323	membrane
H7F26_01085	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
H7F26_01095	COG0166	Belongs to the GPI family
H7F26_01100	COG1979	alcohol dehydrogenase
H7F26_01105	COG2155	Conserved Protein
H7F26_01110	COG1098	S1 RNA binding domain
H7F26_01115	COG0436	Aminotransferase
H7F26_01120	COG1522	sequence-specific DNA binding
H7F26_01125	COG2267	carboxylic ester hydrolase activity
H7F26_01140	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H7F26_01155	COG5018	Exonuclease
H7F26_01160	COG2814	Major facilitator Superfamily
H7F26_01165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F26_01170	COG3011	Protein conserved in bacteria
H7F26_01180	COG3290	protein histidine kinase activity
H7F26_01185	COG4565	transcriptional regulatory protein
H7F26_01195	COG1183	phosphatidylcholine synthase activity
H7F26_01200	COG0586	Pfam SNARE associated Golgi protein
H7F26_01205	COG0688	phosphatidylethanolamine metabolic process
H7F26_01210	COG3493	citrate carrier protein
H7F26_01220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7F26_01220	COG2111	Na H antiporter
H7F26_01225	COG2111	Na H antiporter
H7F26_01230	COG1006	Multisubunit Na H antiporter MnhC subunit
H7F26_01235	COG0651	ATP synthesis coupled electron transport
H7F26_01240	COG1863	multisubunit Na H antiporter MnhE subunit
H7F26_01245	COG2212	antiporter activity
H7F26_01250	COG1320	monovalent cation:proton antiporter activity
H7F26_01255	COG2050	protein possibly involved in aromatic compounds catabolism
H7F26_01260	COG2197	response regulator
H7F26_01265	COG4585	Histidine kinase
H7F26_01290	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H7F26_01295	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H7F26_01300	COG1335	isochorismatase
H7F26_01305	COG5506	Protein of unknown function (DUF1694)
H7F26_01320	COG0628	permease
H7F26_01325	COG1959	2 iron, 2 sulfur cluster binding
H7F26_01330	COG0657	acetylesterase activity
H7F26_01340	COG1418	mRNA catabolic process
H7F26_01345	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_01355	COG1511	domain protein
H7F26_01360	COG1674	ftsk spoiiie
H7F26_01360	COG0433	COG0433 Predicted ATPase
H7F26_01365	COG4499	WXG100 protein secretion system (Wss), protein YukC
H7F26_01370	COG5417	Belongs to the EsaB family
H7F26_01375	COG4842	Belongs to the WXG100 family
H7F26_01380	COG1115	amino acid carrier protein
H7F26_01385	COG2508	Transcriptional regulator
H7F26_01385	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7F26_01390	COG0686	Belongs to the AlaDH PNT family
H7F26_01400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F26_01405	COG1268	BioY protein
H7F26_01410	COG2056	Na+-H+ antiporter family
H7F26_01415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7F26_01420	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H7F26_01425	COG3584	3D domain protein
H7F26_01440	COG1252	NADH dehydrogenase
H7F26_01445	COG0492	ferredoxin-NADP+ reductase activity
H7F26_01460	COG0456	acetyltransferase
H7F26_01465	COG0316	Belongs to the HesB IscA family
H7F26_01470	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H7F26_01475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F26_01480	COG4844	belongs to the
H7F26_01485	COG1252	NADH dehydrogenase
H7F26_01490	COG5646	InterPro IPR014922
H7F26_01500	COG0457	Tetratricopeptide repeat
H7F26_01505	COG3479	Phenolic acid decarboxylase
H7F26_01515	COG4837	Protein of unknown function (DUF1462)
H7F26_01520	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H7F26_01525	COG1506	peptidase
H7F26_01525	COG0823	Involved in the tonB-independent uptake of proteins
H7F26_01525	COG4946	Tricorn protease homolog
H7F26_01530	COG0083	homoserine kinase activity
H7F26_01535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7F26_01540	COG0460	homoserine dehydrogenase
H7F26_01550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F26_01555	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F26_01560	COG0647	UMP catabolic process
H7F26_01565	COG2445	Protein of unknown function DUF86
H7F26_01570	COG4470	Protein conserved in bacteria
H7F26_01585	COG0739	heme binding
H7F26_01595	COG0733	neurotransmitter:sodium symporter activity
H7F26_01605	COG3377	Domain of unknown function (DUF1805)
H7F26_01610	COG0737	Belongs to the 5'-nucleotidase family
H7F26_01615	COG0730	response to heat
H7F26_01620	COG1801	Protein of unknown function DUF72
H7F26_01630	COG3226	Transcriptional regulator
H7F26_01640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H7F26_01645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F26_01650	COG2508	Transcriptional regulator
H7F26_01655	COG2814	Major facilitator Superfamily
H7F26_01660	COG1288	antiporter activity
H7F26_01665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F26_01670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F26_01675	COG2356	endonuclease I
H7F26_01685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F26_01700	COG0457	Tetratricopeptide repeat
H7F26_01705	COG0719	Fe-S assembly protein
H7F26_01710	COG0822	iron-sulfur transferase activity
H7F26_01715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7F26_01720	COG0719	Fe-S assembly protein
H7F26_01725	COG0396	ATPase activity
H7F26_01735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F26_01740	COG1464	Belongs to the NlpA lipoprotein family
H7F26_01745	COG2011	ABC-type metal ion transport system permease component
H7F26_01750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7F26_01760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_01765	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H7F26_01775	COG0509	glycine decarboxylation via glycine cleavage system
H7F26_01780	COG1393	Belongs to the ArsC family
H7F26_01785	COG1960	acyl-CoA dehydrogenase activity
H7F26_01790	COG0183	Belongs to the thiolase family
H7F26_01795	COG1024	Enoyl-CoA hydratase
H7F26_01795	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F26_01810	COG5577	PFAM Coat F domain
H7F26_01825	COG1120	ATPase activity
H7F26_01830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_01835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_01840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_01855	COG1686	Belongs to the peptidase S11 family
H7F26_01860	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_01865	COG0783	Belongs to the Dps family
H7F26_01870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F26_01875	COG0745	RESPONSE REGULATOR receiver
H7F26_01880	COG2770	Histidine kinase
H7F26_01880	COG2205	protein histidine kinase activity
H7F26_01890	COG1309	transcriptional regulator
H7F26_01895	COG0114	fumarate hydratase activity
H7F26_01905	COG0697	spore germination
H7F26_01910	COG0814	amino acid
H7F26_01925	COG2197	response regulator
H7F26_01930	COG4585	Histidine kinase
H7F26_01935	COG4758	membrane
H7F26_01945	COG1842	Phage shock protein A
H7F26_01950	COG4758	membrane
H7F26_01955	COG4677	pectinesterase activity
H7F26_01960	COG2096	Adenosyltransferase
H7F26_01965	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_01975	COG1454	alcohol dehydrogenase
H7F26_01980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F26_01985	COG1120	ATPase activity
H7F26_01990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_01995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_02000	COG1802	Transcriptional regulator
H7F26_02005	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_02010	COG2258	MOSC domain
H7F26_02015	COG0583	DNA-binding transcription factor activity
H7F26_02025	COG2721	sulfolactate sulfo-lyase activity
H7F26_02030	COG0246	Mannitol dehydrogenase
H7F26_02035	COG1609	Transcriptional regulator
H7F26_02040	COG2211	Major facilitator Superfamily
H7F26_02045	COG1904	glucuronate isomerase
H7F26_02050	COG2205	protein histidine kinase activity
H7F26_02055	COG0745	RESPONSE REGULATOR receiver
H7F26_02060	COG1120	ATPase activity
H7F26_02065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_02070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_02075	COG0531	amino acid
H7F26_02085	COG1988	membrane-bound metal-dependent
H7F26_02090	COG1368	sulfuric ester hydrolase activity
H7F26_02095	COG2814	Major facilitator Superfamily
H7F26_02100	COG0656	L-ascorbic acid biosynthetic process
H7F26_02105	COG1940	carbohydrate kinase activity
H7F26_02110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7F26_02120	COG3973	AAA domain
H7F26_02125	COG2860	membrane
H7F26_02130	COG0456	acetyltransferase
H7F26_02130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H7F26_02135	COG0456	acetyltransferase
H7F26_02140	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H7F26_02145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7F26_02150	COG2217	Heavy metal translocating P-type atpase
H7F26_02155	COG1653	transport
H7F26_02160	COG1175	transmembrane transport
H7F26_02165	COG0395	ABC-type sugar transport system, permease component
H7F26_02170	COG1501	Belongs to the glycosyl hydrolase 31 family
H7F26_02175	COG1472	Belongs to the glycosyl hydrolase 3 family
H7F26_02180	COG1121	(ABC) transporter
H7F26_02185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F26_02190	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7F26_02205	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H7F26_02205	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H7F26_02210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_02210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_02210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_02230	COG2217	Heavy metal translocating P-type atpase
H7F26_02235	COG2608	mercury ion transmembrane transporter activity
H7F26_02240	COG1937	Protein conserved in bacteria
H7F26_02245	COG0693	protein deglycase activity
H7F26_02250	COG1349	DNA-binding transcription factor activity
H7F26_02255	COG1070	Carbohydrate kinase
H7F26_02260	COG4952	isomerase
H7F26_02270	COG3347	Dehydrogenase
H7F26_02270	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_02275	COG2814	Major facilitator Superfamily
H7F26_02280	COG2814	Major facilitator Superfamily
H7F26_02290	COG2124	cytochrome p450
H7F26_02300	COG1846	Transcriptional regulator
H7F26_02310	COG0673	inositol 2-dehydrogenase activity
H7F26_02315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F26_02320	COG1054	Belongs to the UPF0176 family
H7F26_02330	COG1191	sigma factor activity
H7F26_02340	COG2140	Oxalate decarboxylase
H7F26_02390	COG5444	nuclease activity
H7F26_02445	COG1705	Flagellar rod assembly protein muramidase FlgJ
H7F26_02520	COG4626	Terminase
H7F26_02520	COG1802	Transcriptional regulator
H7F26_02545	COG0582	viral genome integration into host DNA
H7F26_02630	COG1396	sequence-specific DNA binding
H7F26_02640	COG0582	viral genome integration into host DNA
H7F26_02650	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H7F26_02655	COG0557	exoribonuclease II activity
H7F26_02660	COG1647	Serine aminopeptidase, S33
H7F26_02665	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7F26_02670	COG2002	toxin-antitoxin pair type II binding
H7F26_02675	COG1476	TRANSCRIPTIONal
H7F26_02680	COG1396	sequence-specific DNA binding
H7F26_02685	COG1396	sequence-specific DNA binding
H7F26_02690	COG1174	glycine betaine transport
H7F26_02695	COG1732	Glycine betaine
H7F26_02700	COG1174	glycine betaine transport
H7F26_02705	COG0517	IMP dehydrogenase activity
H7F26_02705	COG1125	glycine betaine transport
H7F26_02710	COG1510	regulation of RNA biosynthetic process
H7F26_02715	COG2095	MarC family integral membrane protein
H7F26_02725	COG4640	response to antibiotic
H7F26_02730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_02740	COG0693	protein deglycase activity
H7F26_02745	COG0148	phosphopyruvate hydratase activity
H7F26_02750	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H7F26_02755	COG0149	triose-phosphate isomerase activity
H7F26_02760	COG0126	phosphoglycerate kinase activity
H7F26_02765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F26_02770	COG2390	Transcriptional regulator
H7F26_02775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F26_02780	COG1113	amino acid transport
H7F26_02800	COG1556	Lactate utilization protein
H7F26_02805	COG1139	Iron-sulfur cluster binding protein
H7F26_02810	COG0247	lactate metabolic process
H7F26_02815	COG2186	Transcriptional regulator
H7F26_02820	COG1620	l-lactate permease
H7F26_02825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H7F26_02835	COG5039	Polysaccharide pyruvyl transferase
H7F26_02840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F26_02845	COG0110	maltose O-acetyltransferase activity
H7F26_02850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7F26_02855	COG2244	polysaccharide biosynthetic process
H7F26_02860	COG1216	Glycosyl transferase, family 2
H7F26_02865	COG5039	Polysaccharide pyruvyl transferase
H7F26_02870	COG1216	Glycosyl transferase, family 2
H7F26_02880	COG0438	transferase activity, transferring glycosyl groups
H7F26_02885	COG1215	transferase activity, transferring glycosyl groups
H7F26_02890	COG0438	transferase activity, transferring glycosyl groups
H7F26_02895	COG1086	Polysaccharide biosynthesis protein
H7F26_02900	COG0489	protein tyrosine kinase activity
H7F26_02905	COG3944	biosynthesis protein
H7F26_02910	COG1396	sequence-specific DNA binding
H7F26_02915	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F26_02920	COG2271	Major facilitator Superfamily
H7F26_02930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7F26_02945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F26_02955	COG1733	regulation of RNA biosynthetic process
H7F26_02960	COG1902	pentaerythritol trinitrate reductase activity
H7F26_02965	COG1621	beta-fructofuranosidase activity
H7F26_02970	COG1621	beta-fructofuranosidase activity
H7F26_02985	COG0740	serine-type endopeptidase activity
H7F26_02990	COG1611	Belongs to the LOG family
H7F26_02995	COG1694	Mazg nucleotide pyrophosphohydrolase
H7F26_03000	COG1078	dGTPase activity
H7F26_03005	COG0659	secondary active sulfate transmembrane transporter activity
H7F26_03010	COG0288	reversible hydration of carbon dioxide
H7F26_03015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F26_03020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F26_03025	COG0640	Transcriptional regulator
H7F26_03035	COG2732	(Barnase) inhibitor
H7F26_03040	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H7F26_03045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_03050	COG1481	regulation of sporulation
H7F26_03055	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H7F26_03060	COG1660	Displays ATPase and GTPase activities
H7F26_03065	COG1051	belongs to the nudix hydrolase family
H7F26_03070	COG0492	ferredoxin-NADP+ reductase activity
H7F26_03075	COG0457	Tetratricopeptide repeat
H7F26_03080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F26_03085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7F26_03085	COG0140	phosphoribosyl-ATP diphosphatase activity
H7F26_03090	COG0107	imidazoleglycerol-phosphate synthase activity
H7F26_03095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H7F26_03100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H7F26_03105	COG0131	Imidazoleglycerol-phosphate dehydratase
H7F26_03110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H7F26_03115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7F26_03120	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H7F26_03125	COG4990	cell redox homeostasis
H7F26_03130	COG5297	Belongs to the glycosyl hydrolase family 6
H7F26_03135	COG0110	maltose O-acetyltransferase activity
H7F26_03140	COG0546	phosphoglycolate phosphatase activity
H7F26_03145	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H7F26_03150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H7F26_03155	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H7F26_03160	COG1846	Transcriptional regulator
H7F26_03165	COG2814	Major facilitator Superfamily
H7F26_03170	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7F26_03175	COG1950	PFAM Membrane protein of
H7F26_03180	COG1983	PspC domain protein
H7F26_03185	COG3595	metallopeptidase activity
H7F26_03205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H7F26_03210	COG0556	nucleotide-excision repair
H7F26_03215	COG4897	Protein conserved in bacteria
H7F26_03225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F26_03235	COG3409	Peptidoglycan-binding domain 1 protein
H7F26_03235	COG0793	Belongs to the peptidase S41A family
H7F26_03240	COG0473	3-isopropylmalate dehydrogenase activity
H7F26_03245	COG3883	PFAM NLP P60 protein
H7F26_03245	COG0791	NLP P60 protein
H7F26_03250	COG2177	Part of the ABC transporter FtsEX involved in
H7F26_03255	COG2884	Cell division ATP-binding protein ftsE
H7F26_03260	COG2010	Cytochrome c
H7F26_03265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_03275	COG0653	protein targeting
H7F26_03280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H7F26_03295	COG1516	flagellar protein fliS
H7F26_03300	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H7F26_03305	COG1334	flagellar protein FlaG
H7F26_03310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F26_03315	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H7F26_03320	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
H7F26_03330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F26_03335	COG1256	bacterial-type flagellum assembly
H7F26_03335	COG4786	Flagellar basal body rod
H7F26_03340	COG3418	PFAM FlgN family protein
H7F26_03345	COG2747	anti-sigma28 factor FlgM
H7F26_03355	COG1040	competence protein
H7F26_03365	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H7F26_03370	COG1307	EDD domain protein, DegV family
H7F26_03375	COG2197	response regulator
H7F26_03380	COG4585	Histidine kinase
H7F26_03385	COG1739	Uncharacterized protein family UPF0029
H7F26_03390	COG1316	TRANSCRIPTIONal
H7F26_03400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F26_03405	COG0438	transferase activity, transferring glycosyl groups
H7F26_03410	COG1215	transferase activity, transferring glycosyl groups
H7F26_03415	COG3206	protein involved in exopolysaccharide biosynthesis
H7F26_03420	COG3307	-O-antigen
H7F26_03425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F26_03430	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H7F26_03435	COG0297	glycogen (starch) synthase activity
H7F26_03435	COG0438	transferase activity, transferring glycosyl groups
H7F26_03440	COG2244	polysaccharide biosynthetic process
H7F26_03450	COG2247	cell wall binding repeat
H7F26_03450	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_03455	COG2385	sporulation resulting in formation of a cellular spore
H7F26_03455	COG2247	cell wall binding repeat
H7F26_03465	COG1316	TRANSCRIPTIONal
H7F26_03470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H7F26_03475	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7F26_03480	COG1134	teichoic acid transport
H7F26_03485	COG1682	transport, permease protein
H7F26_03500	COG0463	Glycosyl transferase, family 2
H7F26_03500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F26_03505	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F26_03510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H7F26_03515	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H7F26_03520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F26_03525	COG4193	domain, Protein
H7F26_03530	COG1482	cell wall glycoprotein biosynthetic process
H7F26_03550	COG0800	Aldolase
H7F26_03555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F26_03560	COG1609	Transcriptional regulator
H7F26_03565	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H7F26_03570	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_03575	COG1063	alcohol dehydrogenase
H7F26_03585	COG2814	Major facilitator Superfamily
H7F26_03590	COG1316	TRANSCRIPTIONal
H7F26_03595	COG0561	phosphatase activity
H7F26_03600	COG0791	NLP P60 protein
H7F26_03610	COG2843	Capsule synthesis protein
H7F26_03620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F26_03625	COG1609	Transcriptional regulator
H7F26_03630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F26_03635	COG1869	D-ribose catabolic process
H7F26_03640	COG1129	ABC transporter
H7F26_03645	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F26_03650	COG1879	ABC-type sugar transport system periplasmic component
H7F26_03655	COG3527	Alpha-acetolactate decarboxylase
H7F26_03660	COG0028	Belongs to the TPP enzyme family
H7F26_03665	COG0583	DNA-binding transcription factor activity
H7F26_03675	COG0405	Gamma-glutamyltransferase
H7F26_03680	COG1522	sequence-specific DNA binding
H7F26_03685	COG2059	Chromate
H7F26_03690	COG2059	Chromate
H7F26_03695	COG4464	protein tyrosine phosphatase activity
H7F26_03700	COG3944	biosynthesis protein
H7F26_03710	COG4715	Zinc finger, swim domain protein
H7F26_03715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7F26_03725	COG0561	phosphatase activity
H7F26_03730	COG1349	DNA-binding transcription factor activity
H7F26_03740	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_03750	COG3732	PTS system glucitol sorbitol-specific
H7F26_03770	COG0629	single-stranded DNA binding
H7F26_03785	COG1970	mechanosensitive ion channel activity
H7F26_03790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F26_03795	COG4786	Flagellar basal body rod
H7F26_03800	COG4786	Flagellar basal body rod
H7F26_03805	COG1077	Cell shape determining protein MreB Mrl
H7F26_03810	COG1609	Transcriptional regulator
H7F26_03815	COG1846	Transcriptional regulator
H7F26_03820	COG2814	Major facilitator Superfamily
H7F26_03825	COG0671	phosphoesterase, PA-phosphatase related
H7F26_03830	COG1227	inorganic diphosphatase activity
H7F26_03835	COG3546	catalase activity
H7F26_03840	COG3361	conserved protein (COG2071)
H7F26_03845	COG0517	IMP dehydrogenase activity
H7F26_03850	COG0598	Magnesium transport protein CorA
H7F26_03855	COG1253	flavin adenine dinucleotide binding
H7F26_03860	COG0004	ammonium transporteR
H7F26_03865	COG0347	Belongs to the P(II) protein family
H7F26_03870	COG0740	serine-type endopeptidase activity
H7F26_03880	COG0739	heme binding
H7F26_03885	COG1247	-acetyltransferase
H7F26_03895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F26_03905	COG0477	Major facilitator Superfamily
H7F26_03910	COG3251	PFAM MbtH domain protein
H7F26_03915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F26_03920	COG1535	isochorismatase
H7F26_03920	COG3433	isochorismatase activity
H7F26_03925	COG1021	2,3-dihydroxybenzoate-AMP ligase
H7F26_03930	COG1169	isochorismate synthase
H7F26_03935	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_03940	COG2819	hydrolase of the alpha beta superfamily
H7F26_03945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_03950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_03955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_03960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_03960	COG2207	Transcriptional regulator
H7F26_03970	COG2910	NAD(P)H-binding
H7F26_03975	COG1959	2 iron, 2 sulfur cluster binding
H7F26_03985	COG1994	Peptidase M50
H7F26_03990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7F26_03995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7F26_04000	COG2223	nitrite transmembrane transporter activity
H7F26_04005	COG3383	formate dehydrogenase (NAD+) activity
H7F26_04010	COG2304	oxidoreductase activity
H7F26_04015	COG2304	oxidoreductase activity
H7F26_04020	COG2385	sporulation resulting in formation of a cellular spore
H7F26_04025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F26_04035	COG4836	Membrane
H7F26_04040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H7F26_04045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H7F26_04050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H7F26_04055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H7F26_04060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F26_04065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H7F26_04070	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F26_04085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H7F26_04090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H7F26_04095	COG4475	Protein of unknown function (DUF436)
H7F26_04100	COG0698	ribose 5-phosphate isomerase
H7F26_04105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F26_04110	COG1971	Probably functions as a manganese efflux pump
H7F26_04115	COG0009	L-threonylcarbamoyladenylate synthase
H7F26_04120	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H7F26_04130	COG0738	Major facilitator superfamily
H7F26_04135	COG0673	inositol 2-dehydrogenase activity
H7F26_04140	COG0561	phosphatase activity
H7F26_04145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F26_04150	COG1609	Transcriptional regulator
H7F26_04155	COG2890	protein-(glutamine-N5) methyltransferase activity
H7F26_04160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H7F26_04165	COG0346	lactoylglutathione lyase activity
H7F26_04170	COG0789	Transcriptional regulator
H7F26_04175	COG0679	Auxin Efflux Carrier
H7F26_04180	COG0281	malic enzyme
H7F26_04185	COG1435	thymidine kinase activity
H7F26_04190	COG0254	rRNA binding
H7F26_04195	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H7F26_04200	COG1494	fructose-1,6-bisphosphatase
H7F26_04205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F26_04210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7F26_04215	COG0191	fructose-bisphosphate aldolase activity
H7F26_04220	COG2204	response regulator
H7F26_04225	COG4821	SIS domain
H7F26_04235	COG0504	CTP synthase activity
H7F26_04240	COG3343	RNA polymerase activity
H7F26_04250	COG1960	acyl-CoA dehydrogenase activity
H7F26_04255	COG1960	acyl-CoA dehydrogenase activity
H7F26_04260	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F26_04265	COG0183	Belongs to the thiolase family
H7F26_04270	COG0247	lactate metabolic process
H7F26_04270	COG2181	nitrate reductase activity
H7F26_04275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F26_04285	COG0018	arginyl-trna synthetase
H7F26_04290	COG4506	Protein conserved in bacteria
H7F26_04295	COG0010	Belongs to the arginase family
H7F26_04300	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H7F26_04315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F26_04325	COG1994	Peptidase M50
H7F26_04330	COG1942	4-Oxalocrotonate Tautomerase
H7F26_04340	COG3465	dGTPase activity
H7F26_04345	COG1078	dGTPase activity
H7F26_04350	COG4844	belongs to the
H7F26_04375	COG2814	Major facilitator Superfamily
H7F26_04400	COG1414	Transcriptional regulator
H7F26_04410	COG0280	phosphate acetyltransferase
H7F26_04415	COG3253	May function as heme-dependent peroxidase
H7F26_04425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7F26_04445	COG1131	(ABC) transporter
H7F26_04460	COG2363	Small membrane protein
H7F26_04465	COG2233	PERMEase
H7F26_04475	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_04480	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H7F26_04485	COG1216	Glycosyl transferase, family 2
H7F26_04490	COG0351	phosphomethylpyrimidine kinase
H7F26_04500	COG1621	beta-fructofuranosidase activity
H7F26_04505	COG1263	PTS System
H7F26_04505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_04510	COG3711	transcriptional antiterminator
H7F26_04520	COG1404	Belongs to the peptidase S8 family
H7F26_04530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F26_04535	COG0778	Nitroreductase
H7F26_04540	COG1473	amidohydrolase
H7F26_04545	COG0772	Belongs to the SEDS family
H7F26_04550	COG0772	Belongs to the SEDS family
H7F26_04555	COG3314	Sporulation integral membrane protein YlbJ
H7F26_04570	COG0456	acetyltransferase
H7F26_04605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F26_04615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F26_04620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F26_04625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F26_04640	COG3162	membrane
H7F26_04645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_04650	COG1070	Carbohydrate kinase
H7F26_04655	COG2115	Belongs to the xylose isomerase family
H7F26_04665	COG0352	thiamine-phosphate diphosphorylase activity
H7F26_04670	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H7F26_04675	COG0583	DNA-binding transcription factor activity
H7F26_04690	COG1380	Effector of murein hydrolase LrgA
H7F26_04695	COG1346	cytolysis
H7F26_04705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_04710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H7F26_04715	COG0346	lactoylglutathione lyase activity
H7F26_04720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F26_04725	COG1442	glycosyl transferase family 8
H7F26_04735	COG4585	Histidine kinase
H7F26_04740	COG2197	response regulator
H7F26_04745	COG2409	Drug exporters of the RND superfamily
H7F26_04750	COG5522	Integral membrane protein (intg_mem_TP0381)
H7F26_04755	COG2271	Major facilitator Superfamily
H7F26_04760	COG4948	Mandelate Racemase Muconate Lactonizing
H7F26_04765	COG0800	Aldolase
H7F26_04770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F26_04780	COG2234	aminopeptidase activity
H7F26_04785	COG0477	Major facilitator Superfamily
H7F26_04795	COG2357	RelA SpoT domain protein
H7F26_04810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F26_04815	COG1696	Membrane protein involved in D-alanine export
H7F26_04820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F26_04825	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H7F26_04830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F26_04835	COG2814	Major facilitator Superfamily
H7F26_04840	COG1486	melibiose metabolic process
H7F26_04845	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F26_04850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_04855	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_04860	COG3711	transcriptional antiterminator
H7F26_04860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_04865	COG2094	Belongs to the DNA glycosylase MPG family
H7F26_04875	COG0372	Belongs to the citrate synthase family
H7F26_04880	COG2079	MmgE PrpD family protein
H7F26_04885	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H7F26_04900	COG1132	(ABC) transporter
H7F26_04905	COG2755	lipolytic protein G-D-S-L family
H7F26_04920	COG2814	Major facilitator Superfamily
H7F26_04925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F26_04930	COG1131	(ABC) transporter
H7F26_04950	COG1595	DNA-templated transcription, initiation
H7F26_04955	COG2814	Major facilitator Superfamily
H7F26_04960	COG0753	catalase activity
H7F26_04965	COG0753	catalase activity
H7F26_04970	COG0735	belongs to the Fur family
H7F26_04975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H7F26_04980	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F26_04985	COG1131	(ABC) transporter
H7F26_05000	COG1131	(ABC) transporter
H7F26_05055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7F26_05060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H7F26_05065	COG4988	ABC transporter
H7F26_05070	COG1294	oxidase, subunit
H7F26_05075	COG1271	oxidase subunit
H7F26_05080	COG2116	formate transmembrane transporter activity
H7F26_05090	COG0281	malic enzyme
H7F26_05095	COG1757	Na H antiporter
H7F26_05100	COG1027	Aspartate ammonia-lyase
H7F26_05105	COG0252	asparaginase activity
H7F26_05110	COG1396	sequence-specific DNA binding
H7F26_05115	COG2706	6-phosphogluconolactonase activity
H7F26_05120	COG0745	RESPONSE REGULATOR receiver
H7F26_05125	COG2205	protein histidine kinase activity
H7F26_05130	COG1136	(ABC) transporter
H7F26_05135	COG0577	efflux transmembrane transporter activity
H7F26_05140	COG5294	Protein conserved in bacteria
H7F26_05155	COG0726	polysaccharide deacetylase
H7F26_05160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F26_05170	COG3493	citrate carrier protein
H7F26_05175	COG0584	glycerophosphoryl diester phosphodiesterase
H7F26_05190	COG1368	sulfuric ester hydrolase activity
H7F26_05200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_05210	COG2235	arginine
H7F26_05215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7F26_05225	COG0549	Belongs to the carbamate kinase family
H7F26_05240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_05250	COG1595	DNA-templated transcription, initiation
H7F26_05275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F26_05280	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7F26_05285	COG1621	beta-fructofuranosidase activity
H7F26_05290	COG2223	nitrite transmembrane transporter activity
H7F26_05295	COG1609	Transcriptional regulator
H7F26_05310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F26_05315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7F26_05320	COG0463	Glycosyl transferase, family 2
H7F26_05325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F26_05350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F26_05365	COG2723	6-phospho-beta-galactosidase activity
H7F26_05370	COG2190	(PTS) system
H7F26_05370	COG1263	PTS System
H7F26_05370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_05375	COG3711	transcriptional antiterminator
H7F26_05380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F26_05385	COG1122	ATPase activity
H7F26_05390	COG4721	ABC-type cobalt transport system, permease component
H7F26_05395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7F26_05405	COG2224	Isocitrate lyase
H7F26_05410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H7F26_05420	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7F26_05425	COG0577	efflux transmembrane transporter activity
H7F26_05430	COG1136	(ABC) transporter
H7F26_05435	COG2205	protein histidine kinase activity
H7F26_05440	COG0745	RESPONSE REGULATOR receiver
H7F26_05445	COG2723	6-phospho-beta-galactosidase activity
H7F26_05450	COG1263	PTS System
H7F26_05450	COG2190	(PTS) system
H7F26_05450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_05460	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
H7F26_05465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7F26_05470	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F26_05475	COG0513	Belongs to the DEAD box helicase family
H7F26_05505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H7F26_05510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F26_05515	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H7F26_05520	COG2390	Transcriptional regulator
H7F26_05530	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H7F26_05535	COG3706	GGDEF domain
H7F26_05540	COG5298	Protein conserved in bacteria
H7F26_05545	COG1215	transferase activity, transferring glycosyl groups
H7F26_05555	COG3977	Valine--pyruvate aminotransferase
H7F26_05570	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7F26_05580	COG0191	fructose-bisphosphate aldolase activity
H7F26_05585	COG1082	Xylose isomerase domain protein TIM barrel
H7F26_05590	COG1082	Xylose isomerase domain protein TIM barrel
H7F26_05595	COG0673	inositol 2-dehydrogenase activity
H7F26_05600	COG2814	Major facilitator Superfamily
H7F26_05605	COG1082	Xylose isomerase domain protein TIM barrel
H7F26_05610	COG3962	Belongs to the TPP enzyme family
H7F26_05615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F26_05620	COG3718	enzyme involved in inositol metabolism
H7F26_05625	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_05630	COG1349	DNA-binding transcription factor activity
H7F26_05635	COG0667	Aldo Keto reductase
H7F26_05640	COG0584	glycerophosphoryl diester phosphodiesterase
H7F26_05645	COG2271	Major facilitator Superfamily
H7F26_05650	COG0326	Molecular chaperone. Has ATPase activity
H7F26_05655	COG0488	(ABC) transporter
H7F26_05660	COG0561	phosphatase activity
H7F26_05680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_05710	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
H7F26_05715	COG0577	efflux transmembrane transporter activity
H7F26_05720	COG1136	(ABC) transporter
H7F26_05725	COG2205	protein histidine kinase activity
H7F26_05730	COG0745	RESPONSE REGULATOR receiver
H7F26_05740	COG5278	phosphoserine phosphatase activity
H7F26_05740	COG0840	transmembrane signaling receptor activity
H7F26_05745	COG1115	amino acid carrier protein
H7F26_05750	COG0686	Belongs to the AlaDH PNT family
H7F26_05755	COG3867	Arabinogalactan endo-beta-1,4-galactanase
H7F26_05760	COG1874	Beta-galactosidase
H7F26_05765	COG3833	ABC-type maltose transport systems, permease component
H7F26_05770	COG1175	transmembrane transport
H7F26_05775	COG2182	Extracellular solute-binding protein
H7F26_05780	COG1609	Transcriptional regulator
H7F26_05790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F26_05795	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H7F26_05800	COG1940	carbohydrate kinase activity
H7F26_05825	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_05825	COG1454	alcohol dehydrogenase
H7F26_05830	COG0450	alkyl hydroperoxide reductase
H7F26_05835	COG3634	alkyl hydroperoxide reductase activity
H7F26_05860	COG1131	(ABC) transporter
H7F26_05865	COG0842	Transport permease protein
H7F26_05870	COG4585	Histidine kinase
H7F26_05875	COG2197	response regulator
H7F26_05905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H7F26_05920	COG0456	acetyltransferase
H7F26_05935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F26_05940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H7F26_05945	COG4853	Protein conserved in bacteria
H7F26_05950	COG4863	YycH protein
H7F26_05955	COG5002	protein histidine kinase activity
H7F26_05960	COG0745	RESPONSE REGULATOR receiver
H7F26_05985	COG1051	belongs to the nudix hydrolase family
H7F26_05990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H7F26_06000	COG0305	Participates in initiation and elongation during chromosome replication
H7F26_06015	COG3093	addiction module antidote protein HigA
H7F26_06020	COG2807	transmembrane transport
H7F26_06025	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H7F26_06030	COG0363	glucosamine-6-phosphate deaminase activity
H7F26_06035	COG2188	Transcriptional regulator
H7F26_06040	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H7F26_06045	COG1263	PTS System
H7F26_06045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_06050	COG0359	binds to the 23S rRNA
H7F26_06055	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H7F26_06060	COG4241	membrane
H7F26_06070	COG5577	PFAM Coat F domain
H7F26_06075	COG0589	response to stress
H7F26_06080	COG0659	secondary active sulfate transmembrane transporter activity
H7F26_06085	COG2271	Major facilitator Superfamily
H7F26_06090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H7F26_06095	COG0629	single-stranded DNA binding
H7F26_06100	COG0360	Binds together with S18 to 16S ribosomal RNA
H7F26_06105	COG0012	GTP binding
H7F26_06110	COG4481	Protein conserved in bacteria
H7F26_06115	COG3949	Membrane
H7F26_06125	COG1475	DNA binding
H7F26_06130	COG1192	Involved in chromosome partitioning
H7F26_06135	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F26_06145	COG1475	DNA binding
H7F26_06150	COG0357	Ribosomal RNA small subunit methyltransferase G
H7F26_06155	COG0445	tRNA wobble uridine modification
H7F26_06160	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H7F26_06165	COG1847	R3H domain protein
H7F26_06170	COG0706	membrane insertase activity
H7F26_06175	COG0594	ribonuclease P activity
H7F26_06185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7F26_06190	COG0592	DNA-directed DNA polymerase activity
H7F26_06195	COG2501	S4 domain
H7F26_06200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7F26_06210	COG0187	DNA topoisomerase II activity
H7F26_06215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7F26_06250	COG0516	GMP reductase activity
H7F26_06250	COG0517	IMP dehydrogenase activity
H7F26_06255	COG1686	Belongs to the peptidase S11 family
H7F26_06260	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
H7F26_06265	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
H7F26_06270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H7F26_06275	COG1929	Belongs to the glycerate kinase type-1 family
H7F26_06280	COG2610	gluconate transmembrane transporter activity
H7F26_06285	COG3835	regulator
H7F26_06300	COG1428	Deoxynucleoside kinase
H7F26_06305	COG1428	Deoxynucleoside kinase
H7F26_06310	COG3858	chitin binding
H7F26_06310	COG1388	LysM domain
H7F26_06315	COG1335	isochorismatase
H7F26_06320	COG0590	tRNA wobble adenosine to inosine editing
H7F26_06330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7F26_06335	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H7F26_06340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7F26_06385	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
H7F26_06390	COG3853	Toxic anion resistance protein (TelA)
H7F26_06395	COG1982	Orn Lys Arg decarboxylase major
H7F26_06400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H7F26_06405	COG3870	Protein conserved in bacteria
H7F26_06410	COG1728	Protein conserved in bacteria
H7F26_06415	COG0470	DNA polymerase III
H7F26_06420	COG1774	PSP1 C-terminal conserved region
H7F26_06425	COG4467	Involved in initiation control of chromosome replication
H7F26_06430	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H7F26_06435	COG2827	Endonuclease containing a URI domain
H7F26_06440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7F26_06445	COG2002	toxin-antitoxin pair type II binding
H7F26_06450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F26_06450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F26_06455	COG0084	hydrolase, TatD family'
H7F26_06460	COG3583	domain protein
H7F26_06460	COG3584	3D domain protein
H7F26_06465	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H7F26_06470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7F26_06480	COG4466	Protein conserved in bacteria
H7F26_06490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H7F26_06495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F26_06500	COG0251	oxidation-reduction process
H7F26_06505	COG2088	sporulation resulting in formation of a cellular spore
H7F26_06510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7F26_06515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7F26_06520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H7F26_06525	COG0193	aminoacyl-tRNA hydrolase activity
H7F26_06535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7F26_06540	COG2002	toxin-antitoxin pair type II binding
H7F26_06545	COG2244	polysaccharide biosynthetic process
H7F26_06550	COG3956	TIGRFAM MazG family protein
H7F26_06555	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H7F26_06570	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7F26_06575	COG1098	S1 RNA binding domain
H7F26_06590	COG2208	phosphoserine phosphatase activity
H7F26_06595	COG2304	oxidoreductase activity
H7F26_06600	COG0515	serine threonine protein kinase
H7F26_06605	COG0037	tRNA processing
H7F26_06610	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H7F26_06615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F26_06620	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H7F26_06625	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7F26_06630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F26_06635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F26_06640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7F26_06645	COG0512	Glutamine amidotransferase of anthranilate synthase
H7F26_06650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F26_06655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7F26_06660	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H7F26_06665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7F26_06670	COG1396	sequence-specific DNA binding
H7F26_06675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F26_06680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H7F26_06760	COG4463	regulation of RNA biosynthetic process
H7F26_06765	COG3880	PFAM UvrB UvrC protein
H7F26_06770	COG3869	Catalyzes the specific phosphorylation of arginine residues in
H7F26_06775	COG0542	response to heat
H7F26_06780	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H7F26_06785	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
H7F26_06790	COG4956	integral membrane protein (PIN domain superfamily)
H7F26_06795	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H7F26_06800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H7F26_06805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F26_06810	COG1045	serine acetyltransferase
H7F26_06815	COG0215	cysteine-tRNA ligase activity
H7F26_06820	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H7F26_06825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F26_06830	COG3688	RNA-binding protein containing a PIN domain
H7F26_06840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F26_06850	COG0250	Participates in transcription elongation, termination and antitermination
H7F26_06855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H7F26_06860	COG0081	regulation of translation
H7F26_06865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H7F26_06870	COG0222	ribosome binding
H7F26_06875	COG2813	Specifically methylates the guanine in position
H7F26_06880	COG0085	RNA polymerase activity
H7F26_06885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H7F26_06890	COG1358	cellular component organization or biogenesis
H7F26_06895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H7F26_06900	COG0049	tRNA binding
H7F26_06905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7F26_06910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7F26_06920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H7F26_06925	COG0088	Forms part of the polypeptide exit tunnel
H7F26_06930	COG0089	rRNA binding
H7F26_06935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H7F26_06940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H7F26_06945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H7F26_06950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H7F26_06955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H7F26_06960	COG0255	Belongs to the universal ribosomal protein uL29 family
H7F26_06965	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H7F26_06970	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H7F26_06975	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H7F26_06980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H7F26_06985	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F26_06990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H7F26_06995	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H7F26_07000	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H7F26_07005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H7F26_07010	COG1841	ribosomal large subunit assembly
H7F26_07015	COG0200	Binds to the 23S rRNA
H7F26_07020	COG0201	protein transport
H7F26_07025	COG0563	adenylate kinase activity
H7F26_07030	COG0024	Methionine aminopeptidase
H7F26_07035	COG2163	COG2163 Ribosomal protein L14E L6E L27E
H7F26_07040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H7F26_07045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7F26_07050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H7F26_07055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H7F26_07060	COG0202	RNA polymerase activity
H7F26_07065	COG0203	ribosomal protein L17
H7F26_07070	COG1122	ATPase activity
H7F26_07075	COG1122	ATPase activity
H7F26_07080	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F26_07085	COG0101	tRNA pseudouridine synthase activity
H7F26_07090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H7F26_07095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H7F26_07100	COG2318	DinB family
H7F26_07110	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_07115	COG0489	protein tyrosine kinase activity
H7F26_07125	COG2194	sulfuric ester hydrolase activity
H7F26_07130	COG0726	polysaccharide deacetylase
H7F26_07160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F26_07170	COG0385	Bile acid
H7F26_07185	COG3876	Protein conserved in bacteria
H7F26_07190	COG1472	Belongs to the glycosyl hydrolase 3 family
H7F26_07195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F26_07200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_07200	COG1263	PTS System
H7F26_07205	COG1737	Transcriptional regulator
H7F26_07210	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H7F26_07215	COG1683	Conserved Protein
H7F26_07250	COG1595	DNA-templated transcription, initiation
H7F26_07255	COG5662	AntiSigma factor
H7F26_07260	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H7F26_07265	COG4856	YbbR-like protein
H7F26_07270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F26_07275	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7F26_07295	COG1725	Transcriptional regulator
H7F26_07300	COG0640	Transcriptional regulator
H7F26_07305	COG2814	Major facilitator Superfamily
H7F26_07315	COG1132	(ABC) transporter
H7F26_07320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7F26_07345	COG1011	Hydrolase
H7F26_07350	COG1113	amino acid transport
H7F26_07355	COG2851	Citrate transporter
H7F26_07360	COG3181	Tripartite tricarboxylate transporter family receptor
H7F26_07365	COG4565	transcriptional regulatory protein
H7F26_07370	COG3290	protein histidine kinase activity
H7F26_07385	COG2211	Major facilitator Superfamily
H7F26_07405	COG1331	Highly conserved protein containing a thioredoxin domain
H7F26_07410	COG3677	Transposase
H7F26_07445	COG1331	Highly conserved protein containing a thioredoxin domain
H7F26_07450	COG0477	Major facilitator Superfamily
H7F26_07470	COG1283	sodium-dependent phosphate transmembrane transporter activity
H7F26_07475	COG4682	membrane
H7F26_07500	COG0697	spore germination
H7F26_07505	COG1917	Cupin 2, conserved barrel domain protein
H7F26_07505	COG2207	Transcriptional regulator
H7F26_07525	COG0371	Dehydrogenase
H7F26_07530	COG0840	transmembrane signaling receptor activity
H7F26_07535	COG4213	ABC transporter substrate-binding protein
H7F26_07550	COG4257	antibiotic catabolic process
H7F26_07560	COG0833	amino acid
H7F26_07565	COG2040	homocysteine
H7F26_07575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_07575	COG1263	PTS System
H7F26_07575	COG2190	(PTS) system
H7F26_07580	COG0789	Transcriptional regulator
H7F26_07585	COG2323	membrane
H7F26_07590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7F26_07590	COG4451	ribulose bisphosphate carboxylase, small
H7F26_07595	COG2205	protein histidine kinase activity
H7F26_07600	COG1115	amino acid carrier protein
H7F26_07605	COG2066	Belongs to the glutaminase family
H7F26_07610	COG4191	Histidine kinase
H7F26_07615	COG0784	Response regulator, receiver
H7F26_07640	COG3540	Alkaline phosphatase
H7F26_07645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F26_07650	COG0805	protein transport
H7F26_07655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F26_07660	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_07665	COG2271	Major facilitator Superfamily
H7F26_07670	COG4948	Mandelate Racemase Muconate Lactonizing
H7F26_07675	COG2186	Transcriptional regulator
H7F26_07680	COG2721	sulfolactate sulfo-lyase activity
H7F26_07685	COG0745	RESPONSE REGULATOR receiver
H7F26_07690	COG2205	protein histidine kinase activity
H7F26_07695	COG1131	(ABC) transporter
H7F26_07720	COG3173	Aminoglycoside phosphotransferase
H7F26_07725	COG1846	Transcriptional regulator
H7F26_07730	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_07750	COG0789	Transcriptional regulator
H7F26_07775	COG0697	spore germination
H7F26_07780	COG1714	RDD family
H7F26_07785	COG3012	SEC-C Motif Domain Protein
H7F26_07785	COG1405	negative regulation of cell septum assembly
H7F26_07790	COG1131	(ABC) transporter
H7F26_07820	COG1942	4-Oxalocrotonate Tautomerase
H7F26_07825	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_07840	COG1288	antiporter activity
H7F26_07850	COG0456	acetyltransferase
H7F26_07860	COG1164	Oligoendopeptidase f
H7F26_07865	COG2261	transglycosylase associated protein
H7F26_07875	COG0247	lactate metabolic process
H7F26_07880	COG0277	FAD linked oxidase domain protein
H7F26_07885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_07890	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F26_07895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_07900	COG1486	melibiose metabolic process
H7F26_07905	COG2188	Transcriptional regulator
H7F26_07910	COG3394	polysaccharide catabolic process
H7F26_07925	COG3591	Belongs to the peptidase S1B family
H7F26_07930	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_07940	COG1595	DNA-templated transcription, initiation
H7F26_07950	COG3773	Cell wall hydrolase
H7F26_07955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F26_07960	COG0791	NLP P60 protein
H7F26_07960	COG3883	PFAM NLP P60 protein
H7F26_07970	COG1131	(ABC) transporter
H7F26_07975	COG1309	transcriptional regulator
H7F26_07995	COG2310	stress, protein
H7F26_08000	COG2310	stress, protein
H7F26_08005	COG2310	stress, protein
H7F26_08010	COG0861	Integral membrane protein TerC family
H7F26_08030	COG3853	Toxic anion resistance protein (TelA)
H7F26_08035	COG0785	Cytochrome C biogenesis protein
H7F26_08045	COG0789	Transcriptional regulator
H7F26_08050	COG2223	nitrite transmembrane transporter activity
H7F26_08055	COG0039	L-malate dehydrogenase activity
H7F26_08060	COG1620	l-lactate permease
H7F26_08065	COG1280	lysine exporter protein (LysE YggA)
H7F26_08070	COG1113	amino acid transport
H7F26_08075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7F26_08080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7F26_08085	COG3541	Predicted nucleotidyltransferase
H7F26_08090	COG0506	proline dehydrogenase activity
H7F26_08095	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_08100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_08105	COG2508	Transcriptional regulator
H7F26_08110	COG3689	TIGRFAM TIGR03943 family protein
H7F26_08115	COG0701	Predicted permease
H7F26_08120	COG3458	cephalosporin-C deacetylase activity
H7F26_08140	COG0765	amino acid transport
H7F26_08145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F26_08150	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F26_08160	COG2723	6-phospho-beta-galactosidase activity
H7F26_08170	COG3209	COG3209 Rhs family protein
H7F26_08180	COG0515	serine threonine protein kinase
H7F26_08180	COG3266	domain, Protein
H7F26_08190	COG5444	nuclease activity
H7F26_08215	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7F26_08220	COG1177	transmembrane transport
H7F26_08225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F26_08230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F26_08235	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H7F26_08240	COG0697	spore germination
H7F26_08245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F26_08255	COG2819	hydrolase of the alpha beta superfamily
H7F26_08265	COG2364	Membrane
H7F26_08275	COG1131	(ABC) transporter
H7F26_08305	COG1126	abc transporter atp-binding protein
H7F26_08310	COG0765	amino acid transport
H7F26_08315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F26_08320	COG3829	transcription factor binding
H7F26_08325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F26_08330	COG0833	amino acid
H7F26_08335	COG0010	Belongs to the arginase family
H7F26_08340	COG0583	DNA-binding transcription factor activity
H7F26_08345	COG0163	prenyltransferase activity
H7F26_08350	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H7F26_08395	COG5444	nuclease activity
H7F26_08415	COG2972	Histidine kinase
H7F26_08420	COG2207	Transcriptional regulator
H7F26_08420	COG4753	response regulator
H7F26_08425	COG4213	ABC transporter substrate-binding protein
H7F26_08435	COG4214	carbohydrate transport
H7F26_08440	COG2271	Major facilitator Superfamily
H7F26_08445	COG0456	acetyltransferase
H7F26_08445	COG1846	Transcriptional regulator
H7F26_08455	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
H7F26_08460	COG3104	oligopeptide transport
H7F26_08465	COG5434	Belongs to the glycosyl hydrolase 28 family
H7F26_08475	COG0697	spore germination
H7F26_08485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7F26_08490	COG0789	Transcriptional regulator
H7F26_08495	COG1136	(ABC) transporter
H7F26_08500	COG0577	efflux transmembrane transporter activity
H7F26_08505	COG0745	RESPONSE REGULATOR receiver
H7F26_08510	COG5002	protein histidine kinase activity
H7F26_08510	COG3850	Histidine kinase
H7F26_08520	COG0527	aspartate kinase activity
H7F26_08525	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_08530	COG4605	iron ion homeostasis
H7F26_08535	COG4604	ABC transporter, ATP-binding protein
H7F26_08540	COG4607	ABC-type enterochelin transport system periplasmic component
H7F26_08545	COG2814	Major facilitator Superfamily
H7F26_08550	COG1309	transcriptional regulator
H7F26_08560	COG0778	Nitroreductase
H7F26_08565	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7F26_08570	COG0640	Transcriptional regulator
H7F26_08575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F26_08580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F26_08585	COG0531	amino acid
H7F26_08590	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_08595	COG0697	spore germination
H7F26_08605	COG4549	nuclear export factor GLE1
H7F26_08610	COG2372	response to copper ion
H7F26_08610	COG1276	copper resistance
H7F26_08615	COG1349	DNA-binding transcription factor activity
H7F26_08620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F26_08625	COG0243	molybdopterin cofactor binding
H7F26_08630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F26_08635	COG2146	nitrite reductase [NAD(P)H] activity
H7F26_08640	COG1587	Uroporphyrinogen-III synthase
H7F26_08640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7F26_08645	COG1802	Transcriptional regulator
H7F26_08650	COG0471	metal ion transport
H7F26_08655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F26_08660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F26_08670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_08685	COG3959	Transketolase, thiamine diphosphate binding domain
H7F26_08690	COG3958	Transketolase
H7F26_08695	COG0561	phosphatase activity
H7F26_08700	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F26_08705	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F26_08710	COG4336	lyase activity
H7F26_08715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7F26_08720	COG1984	allophanate hydrolase subunit 2
H7F26_08725	COG1414	Transcriptional regulator
H7F26_08730	COG2755	lipolytic protein G-D-S-L family
H7F26_08735	COG2213	PTS system mannitol-specific
H7F26_08740	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_08745	COG0246	Mannitol dehydrogenase
H7F26_08750	COG3711	transcriptional antiterminator
H7F26_08755	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_08760	COG1917	Cupin 2, conserved barrel domain protein
H7F26_08770	COG3871	stress protein (general stress protein 26)
H7F26_08785	COG2814	Major facilitator Superfamily
H7F26_08795	COG1522	sequence-specific DNA binding
H7F26_08800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F26_08800	COG0551	DNA topoisomerase type I activity
H7F26_08805	COG0531	amino acid
H7F26_08810	COG0028	Belongs to the TPP enzyme family
H7F26_08815	COG3397	chitin binding
H7F26_08825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F26_08830	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F26_08835	COG2261	transglycosylase associated protein
H7F26_08840	COG1027	Aspartate ammonia-lyase
H7F26_08845	COG1819	glycosyl
H7F26_08850	COG4876	unkown
H7F26_08855	COG2217	Heavy metal translocating P-type atpase
H7F26_08865	COG0662	Cupin 2, conserved barrel domain protein
H7F26_08875	COG0628	permease
H7F26_08880	COG1301	dicarboxylic acid transport
H7F26_08885	COG1131	(ABC) transporter
H7F26_08890	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F26_08900	COG1960	acyl-CoA dehydrogenase activity
H7F26_08915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_08920	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7F26_08925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7F26_08935	COG0513	Belongs to the DEAD box helicase family
H7F26_08940	COG3402	PFAM membrane-flanked domain
H7F26_08945	COG3428	Bacterial PH domain
H7F26_08950	COG0705	Rhomboid family
H7F26_08955	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7F26_08960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F26_08965	COG0864	Transcriptional regulator
H7F26_08970	COG2337	Toxic component of a toxin-antitoxin (TA) module
H7F26_08975	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F26_08980	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F26_08985	COG2172	sigma factor antagonist activity
H7F26_08990	COG2208	phosphoserine phosphatase activity
H7F26_09000	COG2172	sigma factor antagonist activity
H7F26_09005	COG1191	sigma factor activity
H7F26_09010	COG2208	phosphoserine phosphatase activity
H7F26_09015	COG2183	response to ionizing radiation
H7F26_09020	COG1309	transcriptional regulator
H7F26_09025	COG2409	Drug exporters of the RND superfamily
H7F26_09025	COG1033	growth of symbiont in host cell
H7F26_09035	COG3091	SprT-like family
H7F26_09080	COG1476	TRANSCRIPTIONal
H7F26_09085	COG3239	Fatty acid desaturase
H7F26_09090	COG1278	Cold shock
H7F26_09095	COG1063	alcohol dehydrogenase
H7F26_09100	COG2364	Membrane
H7F26_09105	COG1846	Transcriptional regulator
H7F26_09110	COG0456	acetyltransferase
H7F26_09115	COG2808	Putative FMN-binding domain
H7F26_09125	COG1733	regulation of RNA biosynthetic process
H7F26_09130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_09140	COG0583	DNA-binding transcription factor activity
H7F26_09160	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H7F26_09165	COG1113	amino acid transport
H7F26_09180	COG1595	DNA-templated transcription, initiation
H7F26_09190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F26_09190	COG2755	lipolytic protein G-D-S-L family
H7F26_09195	COG2814	Major facilitator Superfamily
H7F26_09200	COG2972	Histidine kinase
H7F26_09200	COG0745	RESPONSE REGULATOR receiver
H7F26_09205	COG3279	Response regulator of the LytR AlgR family
H7F26_09215	COG3764	Sortase (surface protein transpeptidase)
H7F26_09220	COG2814	Major facilitator Superfamily
H7F26_09260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H7F26_09265	COG0802	atpase or kinase
H7F26_09270	COG1214	PFAM Peptidase M22, glycoprotease
H7F26_09275	COG0456	acetyltransferase
H7F26_09280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H7F26_09285	COG0488	(ABC) transporter
H7F26_09290	COG0315	cyclic pyranopterin monophosphate synthase activity
H7F26_09295	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
H7F26_09300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F26_09305	COG0805	protein transport
H7F26_09315	COG1266	CAAX protease self-immunity
H7F26_09320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H7F26_09325	COG0459	protein refolding
H7F26_09330	COG4974	Belongs to the 'phage' integrase family
H7F26_09335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F26_09445	COG0582	viral genome integration into host DNA
H7F26_09540	COG5280	Phage tail tape measure protein TP901
H7F26_09540	COG3953	SLT domain
H7F26_09595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F26_09615	COG2720	vancomycin resistance protein
H7F26_09630	COG2135	peptidase activity
H7F26_09640	COG1309	transcriptional regulator
H7F26_09645	COG0574	Belongs to the PEP-utilizing enzyme family
H7F26_09645	COG3848	Pyruvate phosphate dikinase
H7F26_09655	COG3189	MarR family transcriptional regulator
H7F26_09660	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
H7F26_09665	COG2272	Belongs to the type-B carboxylesterase lipase family
H7F26_09670	COG2814	Major facilitator Superfamily
H7F26_09675	COG1842	Phage shock protein A
H7F26_09680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7F26_09685	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H7F26_09690	COG4260	virion core protein, lumpy skin disease virus
H7F26_09700	COG1378	Sugar-specific transcriptional regulator TrmB
H7F26_09705	COG1280	lysine exporter protein (LysE YggA)
H7F26_09710	COG3339	Conserved Protein
H7F26_09715	COG0772	Belongs to the SEDS family
H7F26_09740	COG0726	polysaccharide deacetylase
H7F26_09750	COG1609	Transcriptional regulator
H7F26_09755	COG0366	Alpha amylase catalytic
H7F26_09760	COG2182	Extracellular solute-binding protein
H7F26_09765	COG1175	transmembrane transport
H7F26_09770	COG3833	ABC-type maltose transport systems, permease component
H7F26_09775	COG5521	maltodextrose utilization protein MalA
H7F26_09780	COG1554	hydrolase, family 65, central catalytic
H7F26_09785	COG0366	Alpha amylase catalytic
H7F26_09790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F26_09795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7F26_09800	COG1846	Transcriptional regulator
H7F26_09815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7F26_09820	COG0823	Involved in the tonB-independent uptake of proteins
H7F26_09850	COG0702	epimerase
H7F26_09860	COG2132	Multicopper oxidase
H7F26_09875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F26_09880	COG0714	Associated with various cellular activities
H7F26_09885	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
H7F26_09890	COG1305	Transglutaminase-like
H7F26_09895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7F26_09895	COG0519	Catalyzes the synthesis of GMP from XMP
H7F26_09900	COG2252	PERMEase
H7F26_09915	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
H7F26_09925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H7F26_09930	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7F26_09935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7F26_09940	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H7F26_09945	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F26_09950	COG0047	phosphoribosylformylglycinamidine synthase activity
H7F26_09955	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F26_09960	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H7F26_09965	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H7F26_09970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7F26_09975	COG0138	bifunctional purine biosynthesis protein purh
H7F26_09980	COG0151	Belongs to the GarS family
H7F26_09990	COG2124	cytochrome p450
H7F26_10010	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7F26_10015	COG1470	cell adhesion involved in biofilm formation
H7F26_10020	COG4496	protein, YerC YecD
H7F26_10025	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
H7F26_10030	COG0210	DNA helicase
H7F26_10035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H7F26_10040	COG4851	CamS sex pheromone cAM373 precursor
H7F26_10045	COG2188	Transcriptional regulator
H7F26_10065	COG1735	metal-dependent hydrolase with the TIM-barrel fold
H7F26_10070	COG0626	cystathionine gamma-synthase activity
H7F26_10075	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H7F26_10080	COG3457	Alanine racemase
H7F26_10085	COG0363	glucosamine-6-phosphate deaminase activity
H7F26_10090	COG1285	pathogenesis
H7F26_10095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_10100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F26_10105	COG0154	amidase activity
H7F26_10110	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F26_10125	COG4124	Belongs to the glycosyl hydrolase 26 family
H7F26_10130	COG1309	transcriptional regulator
H7F26_10135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F26_10145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F26_10150	COG1957	nucleoside hydrolase
H7F26_10155	COG1597	lipid kinase activity
H7F26_10160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F26_10170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_10170	COG1263	PTS System
H7F26_10170	COG2190	(PTS) system
H7F26_10175	COG2723	6-phospho-beta-galactosidase activity
H7F26_10180	COG3711	transcriptional antiterminator
H7F26_10185	COG0457	Tetratricopeptide repeat
H7F26_10200	COG0217	transcriptional regulatory protein
H7F26_10215	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_10220	COG0840	transmembrane signaling receptor activity
H7F26_10225	COG0471	metal ion transport
H7F26_10230	COG0488	(ABC) transporter
H7F26_10240	COG1469	GTP cyclohydrolase I activity
H7F26_10255	COG0523	cobalamin synthesis protein
H7F26_10260	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
H7F26_10265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F26_10270	COG0156	8-amino-7-oxononanoate synthase activity
H7F26_10275	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H7F26_10280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H7F26_10285	COG2124	cytochrome p450
H7F26_10295	COG0789	Transcriptional regulator
H7F26_10300	COG2814	Major facilitator Superfamily
H7F26_10305	COG0488	(ABC) transporter
H7F26_10310	COG0513	Belongs to the DEAD box helicase family
H7F26_10315	COG2130	NADP-dependent
H7F26_10330	COG0471	metal ion transport
H7F26_10350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_10360	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
H7F26_10365	COG5658	integral membrane protein
H7F26_10370	COG0640	Transcriptional regulator
H7F26_10375	COG1254	Belongs to the acylphosphatase family
H7F26_10380	COG2258	MOSC domain
H7F26_10395	COG0024	Methionine aminopeptidase
H7F26_10400	COG1368	sulfuric ester hydrolase activity
H7F26_10410	COG1115	amino acid carrier protein
H7F26_10415	COG1263	PTS System
H7F26_10415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_10420	COG0366	Alpha amylase catalytic
H7F26_10425	COG2188	Transcriptional regulator
H7F26_10450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F26_10455	COG1045	serine acetyltransferase
H7F26_10460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F26_10470	COG1215	transferase activity, transferring glycosyl groups
H7F26_10475	COG0463	Glycosyl transferase, family 2
H7F26_10475	COG0457	Tetratricopeptide repeat
H7F26_10485	COG0673	inositol 2-dehydrogenase activity
H7F26_10495	COG0657	acetylesterase activity
H7F26_10500	COG1733	regulation of RNA biosynthetic process
H7F26_10505	COG0778	Nitroreductase
H7F26_10510	COG0737	Belongs to the 5'-nucleotidase family
H7F26_10515	COG0693	protein deglycase activity
H7F26_10520	COG4840	Belongs to the UPF0435 family
H7F26_10525	COG1115	amino acid carrier protein
H7F26_10530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F26_10535	COG4980	gas vesicle protein
H7F26_10540	COG1295	ribonuclease BN
H7F26_10545	COG0477	Major facilitator Superfamily
H7F26_10555	COG0387	Pfam Sodium calcium exchanger
H7F26_10565	COG0535	radical SAM domain protein
H7F26_10575	COG0726	polysaccharide deacetylase
H7F26_10580	COG0371	Dehydrogenase
H7F26_10590	COG0598	Magnesium transport protein CorA
H7F26_10595	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H7F26_10600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F26_10605	COG4637	Psort location Cytoplasmic, score
H7F26_10630	COG1819	glycosyl
H7F26_10640	COG0477	Major facilitator Superfamily
H7F26_10645	COG1263	PTS System
H7F26_10645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_10650	COG3711	transcriptional antiterminator
H7F26_10655	COG0288	reversible hydration of carbon dioxide
H7F26_10660	COG3002	Belongs to the UPF0753 family
H7F26_10665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7F26_10670	COG5609	conserved protein (DUF2294)
H7F26_10680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F26_10685	COG0022	dehydrogenase e1 component
H7F26_10690	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F26_10695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F26_10700	COG3284	Transcriptional regulator
H7F26_10705	COG1742	UPF0060 membrane protein
H7F26_10710	COG1486	melibiose metabolic process
H7F26_10715	COG1737	Transcriptional regulator
H7F26_10720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_10720	COG1263	PTS System
H7F26_10735	COG1733	regulation of RNA biosynthetic process
H7F26_10740	COG2259	Doxx family
H7F26_10745	COG2514	catechol 2,3-dioxygenase activity
H7F26_10755	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F26_10760	COG2207	Transcriptional regulator
H7F26_10760	COG1917	Cupin 2, conserved barrel domain protein
H7F26_10765	COG1653	transport
H7F26_10770	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F26_10775	COG1051	belongs to the nudix hydrolase family
H7F26_10785	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H7F26_10785	COG0392	lysyltransferase activity
H7F26_10790	COG0384	phenazine biosynthesis protein PhzF
H7F26_10795	COG0778	Nitroreductase
H7F26_10815	COG1090	epimerase
H7F26_10820	COG2137	regulation of response to DNA damage stimulus
H7F26_10845	COG0463	Glycosyl transferase, family 2
H7F26_10855	COG4485	Bacterial membrane protein, YfhO
H7F26_10860	COG1988	membrane-bound metal-dependent
H7F26_10865	COG1194	a g-specific adenine glycosylase
H7F26_10875	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_10890	COG3557	Belongs to the UPF0374 family
H7F26_10895	COG1132	(ABC) transporter
H7F26_10900	COG0444	Belongs to the ABC transporter superfamily
H7F26_10905	COG4608	Belongs to the ABC transporter superfamily
H7F26_10910	COG0747	negative chemotaxis
H7F26_10915	COG0601	transmembrane transport
H7F26_10920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F26_10925	COG4129	membrane
H7F26_10930	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F26_10935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7F26_10940	COG0735	belongs to the Fur family
H7F26_11050	COG4974	Belongs to the 'phage' integrase family
H7F26_11060	COG0582	viral genome integration into host DNA
H7F26_11180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F26_11190	COG0710	3-dehydroquinate dehydratase activity
H7F26_11195	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H7F26_11200	COG1116	anion transmembrane transporter activity
H7F26_11205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F26_11210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F26_11215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F26_11225	COG1476	TRANSCRIPTIONal
H7F26_11235	COG1131	(ABC) transporter
H7F26_11255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F26_11265	COG3382	B3 4 domain protein
H7F26_11270	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7F26_11280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7F26_11285	COG0789	Transcriptional regulator
H7F26_11290	COG1664	Polymer-forming cytoskeletal
H7F26_11300	COG2766	serine protein kinase
H7F26_11305	COG2718	Belongs to the UPF0229 family
H7F26_11315	COG1566	PFAM secretion protein HlyD family protein
H7F26_11320	COG2814	Major facilitator Superfamily
H7F26_11325	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7F26_11335	COG1131	(ABC) transporter
H7F26_11340	COG1131	(ABC) transporter
H7F26_11345	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F26_11350	COG1278	Cold shock
H7F26_11355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7F26_11360	COG2011	ABC-type metal ion transport system permease component
H7F26_11365	COG1464	Belongs to the NlpA lipoprotein family
H7F26_11370	COG1823	symporter activity
H7F26_11395	COG5577	PFAM Coat F domain
H7F26_11400	COG5002	protein histidine kinase activity
H7F26_11405	COG4085	toxin activity
H7F26_11405	COG1525	nuclease
H7F26_11405	COG0737	Belongs to the 5'-nucleotidase family
H7F26_11410	COG3764	Sortase (surface protein transpeptidase)
H7F26_11415	COG0564	pseudouridine synthase activity
H7F26_11425	COG0517	IMP dehydrogenase activity
H7F26_11430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F26_11435	COG3153	acetyltransferase
H7F26_11435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F26_11440	COG0488	(ABC) transporter
H7F26_11445	COG2116	formate transmembrane transporter activity
H7F26_11450	COG0679	Auxin Efflux Carrier
H7F26_11455	COG0604	alcohol dehydrogenase
H7F26_11460	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H7F26_11465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7F26_11470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7F26_11475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H7F26_11480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F26_11495	COG4585	Histidine kinase
H7F26_11495	COG2203	Gaf domain
H7F26_11500	COG2197	response regulator
H7F26_11505	COG0431	NADPH-dependent FMN reductase
H7F26_11520	COG1959	2 iron, 2 sulfur cluster binding
H7F26_11525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7F26_11525	COG1017	nitric oxide dioxygenase activity
H7F26_11530	COG2719	SpoVR family
H7F26_11535	COG0791	NLP P60 protein
H7F26_11535	COG1388	LysM domain
H7F26_11540	COG0583	DNA-binding transcription factor activity
H7F26_11545	COG0372	Belongs to the citrate synthase family
H7F26_11550	COG2133	pyrroloquinoline quinone binding
H7F26_11555	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_11560	COG0733	neurotransmitter:sodium symporter activity
H7F26_11570	COG2207	Transcriptional regulator
H7F26_11570	COG3708	Transcriptional regulator
H7F26_11575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F26_11595	COG1595	DNA-templated transcription, initiation
H7F26_11600	COG0662	Cupin 2, conserved barrel domain protein
H7F26_11605	COG0204	Acyl-transferase
H7F26_11610	COG3152	Membrane
H7F26_11620	COG1309	transcriptional regulator
H7F26_11625	COG1253	flavin adenine dinucleotide binding
H7F26_11630	COG0789	Transcriptional regulator
H7F26_11635	COG1253	flavin adenine dinucleotide binding
H7F26_11655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F26_11660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F26_11665	COG0584	glycerophosphoryl diester phosphodiesterase
H7F26_11675	COG0668	transmembrane transport
H7F26_11680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H7F26_11690	COG0726	polysaccharide deacetylase
H7F26_11700	COG1757	Na H antiporter
H7F26_11705	COG2017	converts alpha-aldose to the beta-anomer
H7F26_11730	COG0589	response to stress
H7F26_11735	COG1132	(ABC) transporter
H7F26_11740	COG1132	(ABC) transporter
H7F26_11745	COG0702	epimerase
H7F26_11765	COG3842	ATPase activity
H7F26_11770	COG2508	Transcriptional regulator
H7F26_11780	COG0189	ligase activity
H7F26_11785	COG0189	ligase activity
H7F26_11790	COG4399	Belongs to the UPF0754 family
H7F26_11795	COG3679	Belongs to the UPF0342 family
H7F26_11800	COG0561	phosphatase activity
H7F26_11805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F26_11810	COG0475	glutathione-regulated potassium exporter activity
H7F26_11815	COG0490	domain, Protein
H7F26_11825	COG1024	Enoyl-CoA hydratase
H7F26_11830	COG0457	Tetratricopeptide repeat
H7F26_11850	COG4152	abc transporter atp-binding protein
H7F26_11855	COG1668	transmembrane transport
H7F26_11860	COG0420	3'-5' exonuclease activity
H7F26_11865	COG4717	serine-type aminopeptidase activity
H7F26_11870	COG3481	metal-dependent phosphohydrolase, HD sub domain
H7F26_11880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F26_11910	COG1846	Transcriptional regulator
H7F26_11915	COG4980	gas vesicle protein
H7F26_11925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H7F26_11930	COG0537	adenosine 5'-monophosphoramidase activity
H7F26_11935	COG1131	(ABC) transporter
H7F26_11940	COG4473	ABC transporter
H7F26_11950	COG1473	amidohydrolase
H7F26_11955	COG3069	C4-dicarboxylate transmembrane transporter activity
H7F26_11960	COG2329	Antibiotic biosynthesis monooxygenase
H7F26_11965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F26_11970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H7F26_11975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H7F26_11980	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H7F26_11985	COG1309	transcriptional regulator
H7F26_11990	COG1511	domain protein
H7F26_11995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F26_12000	COG1363	Peptidase, m42
H7F26_12010	COG1301	dicarboxylic acid transport
H7F26_12020	COG1234	tRNA 3'-trailer cleavage
H7F26_12025	COG0095	Lipoate-protein ligase
H7F26_12030	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_12040	COG1396	sequence-specific DNA binding
H7F26_12055	COG0501	Belongs to the peptidase M48B family
H7F26_12065	COG0697	spore germination
H7F26_12070	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H7F26_12075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_12080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_12085	COG0406	alpha-ribazole phosphatase activity
H7F26_12090	COG0840	transmembrane signaling receptor activity
H7F26_12095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F26_12095	COG0723	plastoquinol--plastocyanin reductase activity
H7F26_12100	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_12110	COG4903	ComK protein
H7F26_12120	COG0398	Pfam SNARE associated Golgi protein
H7F26_12125	COG0681	Belongs to the peptidase S26 family
H7F26_12130	COG1404	Belongs to the peptidase S8 family
H7F26_12140	COG2508	Transcriptional regulator
H7F26_12150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H7F26_12155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F26_12160	COG3257	ureidoglycine aminohydrolase activity
H7F26_12165	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H7F26_12170	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H7F26_12175	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F26_12180	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F26_12195	COG2814	Major facilitator Superfamily
H7F26_12205	COG0457	Tetratricopeptide repeat
H7F26_12225	COG1609	Transcriptional regulator
H7F26_12230	COG1653	transport
H7F26_12235	COG1175	transmembrane transport
H7F26_12240	COG0395	ABC-type sugar transport system, permease component
H7F26_12245	COG1486	melibiose metabolic process
H7F26_12250	COG3180	Ammonia monooxygenase
H7F26_12265	COG3546	catalase activity
H7F26_12270	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_12275	COG0477	Major facilitator Superfamily
H7F26_12275	COG2814	Major facilitator Superfamily
H7F26_12285	COG5002	protein histidine kinase activity
H7F26_12290	COG0745	RESPONSE REGULATOR receiver
H7F26_12295	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
H7F26_12300	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7F26_12305	COG4149	molybdate abc transporter
H7F26_12310	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H7F26_12315	COG1074	ATP-dependent DNA helicase activity
H7F26_12320	COG0420	3'-5' exonuclease activity
H7F26_12325	COG0419	ATPase involved in DNA repair
H7F26_12370	COG5337	Spore coat protein CotH
H7F26_12380	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F26_12400	COG0367	asparagine synthase
H7F26_12415	COG0534	Mate efflux family protein
H7F26_12420	COG1917	Cupin 2, conserved barrel domain protein
H7F26_12420	COG2207	Transcriptional regulator
H7F26_12430	COG1609	Transcriptional regulator
H7F26_12435	COG0673	inositol 2-dehydrogenase activity
H7F26_12440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F26_12450	COG0076	glutamate decarboxylase activity
H7F26_12475	COG2153	protein acetylation
H7F26_12480	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_12485	COG2378	regulation of single-species biofilm formation
H7F26_12490	COG1410	methionine synthase
H7F26_12490	COG0646	methionine synthase
H7F26_12495	COG0646	methionine synthase
H7F26_12495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H7F26_12500	COG1666	GTP binding
H7F26_12505	COG2996	Protein conserved in bacteria
H7F26_12520	COG1307	EDD domain protein, DegV family
H7F26_12525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_12535	COG0516	GMP reductase activity
H7F26_12550	COG0561	phosphatase activity
H7F26_12555	COG1073	alpha beta
H7F26_12560	COG2151	metal-sulfur cluster biosynthetic enzyme
H7F26_12565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H7F26_12570	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H7F26_12575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7F26_12580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F26_12585	COG0505	Belongs to the CarA family
H7F26_12590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F26_12595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7F26_12600	COG1968	undecaprenyl-diphosphatase activity
H7F26_12615	COG2267	carboxylic ester hydrolase activity
H7F26_12625	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F26_12640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F26_12645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F26_12650	COG5504	Zn-dependent protease
H7F26_12655	COG0444	Belongs to the ABC transporter superfamily
H7F26_12660	COG4608	Belongs to the ABC transporter superfamily
H7F26_12670	COG0601	transmembrane transport
H7F26_12675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F26_12700	COG0180	Tryptophanyl-tRNA synthetase
H7F26_12710	COG0601	transmembrane transport
H7F26_12715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F26_12720	COG0444	Belongs to the ABC transporter superfamily
H7F26_12725	COG4608	Belongs to the ABC transporter superfamily
H7F26_12730	COG0456	acetyltransferase
H7F26_12735	COG1393	Belongs to the ArsC family
H7F26_12740	COG0861	Integral membrane protein TerC family
H7F26_12750	COG4862	establishment of competence for transformation
H7F26_12770	COG4565	transcriptional regulatory protein
H7F26_12775	COG3290	protein histidine kinase activity
H7F26_12780	COG4469	Competence protein
H7F26_12785	COG1164	Oligoendopeptidase f
H7F26_12790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7F26_12795	COG2346	COG2346, Truncated hemoglobins
H7F26_12800	COG0741	lytic transglycosylase activity
H7F26_12805	COG4116	CYTH
H7F26_12815	COG2357	RelA SpoT domain protein
H7F26_12820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F26_12825	COG0564	pseudouridine synthase activity
H7F26_12830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7F26_12835	COG0475	glutathione-regulated potassium exporter activity
H7F26_12835	COG0569	domain protein
H7F26_12840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7F26_12845	COG0352	thiamine-phosphate diphosphorylase activity
H7F26_12855	COG2104	thiamine diphosphate biosynthetic process
H7F26_12860	COG2022	thiamine diphosphate biosynthetic process
H7F26_12865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F26_12870	COG0351	phosphomethylpyrimidine kinase
H7F26_12875	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H7F26_12930	COG0210	DNA helicase
H7F26_12940	COG0586	Pfam SNARE associated Golgi protein
H7F26_12945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F26_12950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7F26_12955	COG2246	polysaccharide biosynthetic process
H7F26_12960	COG2153	protein acetylation
H7F26_12965	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7F26_12970	COG2382	esterase
H7F26_12985	COG0626	cystathionine gamma-synthase activity
H7F26_12990	COG0626	cystathionine gamma-synthase activity
H7F26_12995	COG5505	Protein of unknown function (DUF819)
H7F26_13010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F26_13015	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F26_13030	COG0110	maltose O-acetyltransferase activity
H7F26_13040	COG0583	DNA-binding transcription factor activity
H7F26_13045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F26_13050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F26_13060	COG0583	DNA-binding transcription factor activity
H7F26_13065	COG0697	spore germination
H7F26_13070	COG0346	lactoylglutathione lyase activity
H7F26_13080	COG1388	LysM domain
H7F26_13080	COG3584	3D domain protein
H7F26_13085	COG2814	Major facilitator Superfamily
H7F26_13090	COG1309	transcriptional regulator
H7F26_13110	COG5444	nuclease activity
H7F26_13115	COG4195	phage-related replication protein
H7F26_13120	COG2856	Zn peptidase
H7F26_13125	COG1396	sequence-specific DNA binding
H7F26_13140	COG1522	sequence-specific DNA binding
H7F26_13145	COG1484	DNA-dependent DNA replication
H7F26_13165	COG1595	DNA-templated transcription, initiation
H7F26_13170	COG3728	DNA packaging
H7F26_13170	COG5484	DNA packaging
H7F26_13175	COG1783	phage Terminase large subunit
H7F26_13180	COG5518	Phage portal protein
H7F26_13185	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H7F26_13190	COG4653	Phage capsid family
H7F26_13240	COG5412	phage tail tape measure protein
H7F26_13240	COG3953	SLT domain
H7F26_13245	COG1652	LysM domain
H7F26_13250	COG4193	domain, Protein
H7F26_13260	COG3628	GPW Gp25 family protein
H7F26_13265	COG3299	homolog of phage Mu protein gp47
H7F26_13270	COG3778	Protein conserved in bacteria
H7F26_13305	COG1802	Transcriptional regulator
H7F26_13310	COG1063	alcohol dehydrogenase
H7F26_13315	COG1312	Catalyzes the dehydration of D-mannonate
H7F26_13320	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_13325	COG1063	alcohol dehydrogenase
H7F26_13330	COG2271	Major facilitator Superfamily
H7F26_13345	COG0306	phosphate transporter
H7F26_13350	COG1392	Phosphate transport regulator
H7F26_13355	COG0405	Gamma-glutamyltransferase
H7F26_13360	COG5578	integral membrane protein
H7F26_13365	COG2972	Histidine kinase
H7F26_13370	COG2207	Transcriptional regulator
H7F26_13370	COG4753	response regulator
H7F26_13375	COG1653	transport
H7F26_13380	COG1175	transmembrane transport
H7F26_13385	COG0395	ABC-type sugar transport system, permease component
H7F26_13390	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H7F26_13395	COG2207	Transcriptional regulator
H7F26_13400	COG2755	lipolytic protein G-D-S-L family
H7F26_13410	COG5578	integral membrane protein
H7F26_13425	COG2755	lipolytic protein G-D-S-L family
H7F26_13430	COG3401	FG-GAP repeat protein
H7F26_13435	COG0667	Aldo Keto reductase
H7F26_13440	COG2755	lipolytic protein G-D-S-L family
H7F26_13445	COG1874	Beta-galactosidase
H7F26_13455	COG1653	transport
H7F26_13460	COG4209	transmembrane transport
H7F26_13465	COG0395	ABC-type sugar transport system, permease component
H7F26_13470	COG0531	amino acid
H7F26_13475	COG0346	lactoylglutathione lyase activity
H7F26_13485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F26_13490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F26_13495	COG2362	D-Aminopeptidase
H7F26_13500	COG0601	transmembrane transport
H7F26_13505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F26_13510	COG0444	Belongs to the ABC transporter superfamily
H7F26_13515	COG4166	transmembrane transport
H7F26_13520	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F26_13525	COG4948	Mandelate Racemase Muconate Lactonizing
H7F26_13530	COG0791	NLP P60 protein
H7F26_13535	COG4608	Belongs to the ABC transporter superfamily
H7F26_13540	COG1834	amidinotransferase
H7F26_13545	COG1607	acyl-coa hydrolase
H7F26_13555	COG3866	Pectate lyase
H7F26_13575	COG2318	DinB family
H7F26_13580	COG2076	Multidrug Resistance protein
H7F26_13585	COG2076	Multidrug Resistance protein
H7F26_13590	COG0788	formyltetrahydrofolate deformylase activity
H7F26_13595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F26_13600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F26_13605	COG1764	response to oxidative stress
H7F26_13610	COG1846	Transcriptional regulator
H7F26_13615	COG1764	response to oxidative stress
H7F26_13625	COG0590	tRNA wobble adenosine to inosine editing
H7F26_13630	COG0406	alpha-ribazole phosphatase activity
H7F26_13645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F26_13650	COG1404	Belongs to the peptidase S8 family
H7F26_13660	COG2239	Acts as a magnesium transporter
H7F26_13670	COG0582	viral genome integration into host DNA
H7F26_13675	COG2856	Zn peptidase
H7F26_13690	COG3620	sequence-specific DNA binding
H7F26_13705	COG3646	Phage regulatory protein
H7F26_13705	COG3645	SOS response
H7F26_13755	COG1484	DNA-dependent DNA replication
H7F26_13795	COG3331	DNA recombination
H7F26_13810	COG0629	single-stranded DNA binding
H7F26_13875	COG3728	DNA packaging
H7F26_13875	COG5484	DNA packaging
H7F26_13880	COG1783	phage Terminase large subunit
H7F26_14015	COG5444	nuclease activity
H7F26_14030	COG0789	Transcriptional regulator
H7F26_14045	COG1846	Transcriptional regulator
H7F26_14050	COG1793	dna ligase
H7F26_14050	COG3285	dna ligase
H7F26_14055	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H7F26_14060	COG3300	MHYT domain
H7F26_14060	COG5001	Diguanylate cyclase
H7F26_14065	COG0586	Pfam SNARE associated Golgi protein
H7F26_14070	COG0861	Integral membrane protein TerC family
H7F26_14075	COG1191	sigma factor activity
H7F26_14095	COG0501	Belongs to the peptidase M48B family
H7F26_14100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7F26_14105	COG0768	penicillin binding
H7F26_14120	COG3594	Acyltransferase
H7F26_14125	COG5002	protein histidine kinase activity
H7F26_14130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7F26_14135	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H7F26_14140	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
H7F26_14145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F26_14150	COG0436	Aminotransferase
H7F26_14155	COG1850	ribulose-bisphosphate carboxylase activity
H7F26_14160	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
H7F26_14160	COG0235	Class ii aldolase
H7F26_14165	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H7F26_14170	COG0346	lactoylglutathione lyase activity
H7F26_14175	COG3339	Conserved Protein
H7F26_14185	COG3852	Histidine kinase
H7F26_14190	COG1846	Transcriptional regulator
H7F26_14195	COG1360	Flagellar Motor Protein
H7F26_14200	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7F26_14205	COG0542	response to heat
H7F26_14210	COG3949	Membrane
H7F26_14215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7F26_14220	COG0720	synthase
H7F26_14225	COG0602	queuosine metabolic process
H7F26_14230	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7F26_14240	COG3739	integral membrane protein
H7F26_14245	COG3655	Transcriptional regulator
H7F26_14280	COG4873	Protein conserved in bacteria
H7F26_14290	COG3773	Cell wall hydrolase
H7F26_14295	COG2244	polysaccharide biosynthetic process
H7F26_14300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_14305	COG2217	Heavy metal translocating P-type atpase
H7F26_14310	COG0006	proline dipeptidase activity
H7F26_14320	COG1609	Transcriptional regulator
H7F26_14325	COG3711	transcriptional antiterminator
H7F26_14330	COG1263	PTS System
H7F26_14330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_14330	COG2190	(PTS) system
H7F26_14335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_14340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7F26_14350	COG1533	DNA photolyase activity
H7F26_14355	COG0456	acetyltransferase
H7F26_14360	COG0840	transmembrane signaling receptor activity
H7F26_14365	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_14370	COG2084	Dehydrogenase
H7F26_14375	COG2340	Cysteine-rich secretory protein family
H7F26_14380	COG0768	penicillin binding
H7F26_14385	COG4191	Histidine kinase
H7F26_14390	COG0436	Aminotransferase
H7F26_14400	COG1714	RDD family
H7F26_14410	COG0835	chemotaxis
H7F26_14410	COG0784	Response regulator, receiver
H7F26_14420	COG2814	Major facilitator Superfamily
H7F26_14425	COG1376	ErfK ybiS ycfS ynhG family protein
H7F26_14430	COG1408	metallophosphoesterase
H7F26_14435	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_14440	COG2200	EAL domain
H7F26_14450	COG4703	Protein of unknown function (DUF1797)
H7F26_14460	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
H7F26_14470	COG0517	IMP dehydrogenase activity
H7F26_14475	COG0583	DNA-binding transcription factor activity
H7F26_14480	COG0716	FMN binding
H7F26_14490	COG0716	FMN binding
H7F26_14495	COG2171	N-acyltransferase activity
H7F26_14500	COG1473	amidohydrolase
H7F26_14510	COG0450	alkyl hydroperoxide reductase
H7F26_14515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_14530	COG0746	molybdenum cofactor guanylyltransferase activity
H7F26_14535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F26_14540	COG0303	'Molybdopterin
H7F26_14545	COG1763	Mo-molybdopterin cofactor biosynthetic process
H7F26_14550	COG0314	molybdopterin synthase activity
H7F26_14555	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H7F26_14565	COG1132	(ABC) transporter
H7F26_14570	COG1132	(ABC) transporter
H7F26_14580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F26_14585	COG1136	(ABC) transporter
H7F26_14590	COG0577	efflux transmembrane transporter activity
H7F26_14595	COG1349	DNA-binding transcription factor activity
H7F26_14600	COG1105	Belongs to the carbohydrate kinase PfkB family
H7F26_14605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_14605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_14605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_14625	COG0488	(ABC) transporter
H7F26_14635	COG2309	aminopeptidase activity
H7F26_14645	COG1077	Cell shape determining protein MreB Mrl
H7F26_14650	COG2002	toxin-antitoxin pair type II binding
H7F26_14655	COG3852	Histidine kinase
H7F26_14660	COG0569	domain protein
H7F26_14665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7F26_14670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H7F26_14675	COG5503	Protein of unknown function (DUF1447)
H7F26_14680	COG0561	phosphatase activity
H7F26_14690	COG0242	peptide deformylase activity
H7F26_14700	COG0497	DNA recombination
H7F26_14705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F26_14710	COG0022	dehydrogenase e1 component
H7F26_14715	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F26_14720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F26_14725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_14735	COG1982	Orn Lys Arg decarboxylase major
H7F26_14740	COG4476	Belongs to the UPF0223 family
H7F26_14745	COG4493	Belongs to the UPF0637 family
H7F26_14755	COG0483	inositol monophosphate 1-phosphatase activity
H7F26_14775	COG1595	DNA-templated transcription, initiation
H7F26_14790	COG1217	gtp-binding protein TYPA
H7F26_14800	COG1846	Transcriptional regulator
H7F26_14805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F26_14810	COG4896	Protein conserved in bacteria
H7F26_14820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H7F26_14825	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F26_14830	COG2066	Belongs to the glutaminase family
H7F26_14835	COG4838	Belongs to the UPF0358 family
H7F26_14840	COG0772	Belongs to the SEDS family
H7F26_14845	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H7F26_14850	COG1612	heme a metabolic process
H7F26_14855	COG0109	protoheme IX farnesyltransferase activity
H7F26_14860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F26_14860	COG2010	Cytochrome c
H7F26_14865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F26_14870	COG1845	cytochrome c oxidase, subunit III
H7F26_14875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F26_14880	COG3336	cytochrome c oxidase
H7F26_14890	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H7F26_14895	COG2340	Cysteine-rich secretory protein family
H7F26_14910	COG3679	Belongs to the UPF0342 family
H7F26_14915	COG4471	UPF0298 protein
H7F26_14920	COG0742	ribosomal rna small subunit methyltransferase
H7F26_14925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H7F26_14930	COG3314	Sporulation integral membrane protein YlbJ
H7F26_14935	COG3480	Lon protease (S16) C-terminal proteolytic domain
H7F26_14940	COG1323	Belongs to the UPF0348 family
H7F26_14945	COG1399	metal-binding, possibly nucleic acid-binding protein
H7F26_14950	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H7F26_14960	COG0454	-acetyltransferase
H7F26_14965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F26_14970	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
H7F26_14975	COG2001	Belongs to the MraZ family
H7F26_14980	COG0275	rRNA processing
H7F26_14985	COG4839	cell division protein FtsL
H7F26_14990	COG0768	penicillin binding
H7F26_14995	COG0768	penicillin binding
H7F26_15000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F26_15005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F26_15010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F26_15015	COG0772	Belongs to the SEDS family
H7F26_15020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F26_15025	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H7F26_15030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7F26_15035	COG3879	Bacterial protein of unknown function (DUF881)
H7F26_15040	COG3879	Bacterial protein of unknown function (DUF881)
H7F26_15045	COG3856	small basic protein
H7F26_15050	COG0849	cell division
H7F26_15055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7F26_15060	COG1404	Belongs to the peptidase S8 family
H7F26_15060	COG4412	M6 family metalloprotease domain protein
H7F26_15065	COG4412	M6 family metalloprotease domain protein
H7F26_15065	COG1404	Belongs to the peptidase S8 family
H7F26_15075	COG1191	sigma factor activity
H7F26_15080	COG1191	sigma factor activity
H7F26_15085	COG1119	ATPase activity
H7F26_15090	COG0500	methyltransferase
H7F26_15095	COG1873	PFAM PRC-barrel domain
H7F26_15100	COG1496	oxidoreductase activity
H7F26_15105	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H7F26_15110	COG1799	cell septum assembly
H7F26_15115	COG0762	integral membrane protein
H7F26_15120	COG2302	S4 RNA-binding domain
H7F26_15125	COG3599	regulation of cell shape
H7F26_15130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H7F26_15135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F26_15140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H7F26_15145	COG0564	pseudouridine synthase activity
H7F26_15150	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H7F26_15155	COG2233	PERMEase
H7F26_15160	COG0540	Belongs to the ATCase OTCase family
H7F26_15165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H7F26_15170	COG0505	Belongs to the CarA family
H7F26_15175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F26_15180	COG0543	2 iron, 2 sulfur cluster binding
H7F26_15185	COG0167	dihydroorotate dehydrogenase activity
H7F26_15190	COG0284	orotidine-5'-phosphate decarboxylase activity
H7F26_15195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H7F26_15205	COG0175	sulfate reduction
H7F26_15210	COG0306	phosphate transporter
H7F26_15215	COG2046	Belongs to the sulfate adenylyltransferase family
H7F26_15220	COG0529	Catalyzes the synthesis of activated sulfate
H7F26_15225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7F26_15230	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
H7F26_15235	COG1648	precorrin-2 dehydrogenase activity
H7F26_15245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7F26_15250	COG1561	YicC-like family, N-terminal region
H7F26_15255	COG2052	Domain of unknown function (DUF370)
H7F26_15260	COG0194	GDP metabolic process
H7F26_15265	COG1758	RNA polymerase activity
H7F26_15270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F26_15275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7F26_15280	COG0242	peptide deformylase activity
H7F26_15285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H7F26_15290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F26_15290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7F26_15295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H7F26_15300	COG0631	protein serine/threonine phosphatase activity
H7F26_15305	COG0515	serine threonine protein kinase
H7F26_15305	COG2815	serine threonine protein kinase
H7F26_15310	COG1162	GTPase activity
H7F26_15315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7F26_15320	COG1564	THIamine pyrophosphokinase
H7F26_15330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H7F26_15335	COG1302	Protein conserved in bacteria
H7F26_15340	COG1461	Dihydroxyacetone kinase
H7F26_15345	COG1760	l-serine dehydratase
H7F26_15350	COG1760	l-serine dehydratase
H7F26_15355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7F26_15360	COG1349	DNA-binding transcription factor activity
H7F26_15365	COG0416	fatty acid biosynthetic process
H7F26_15370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7F26_15375	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_15380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F26_15385	COG0571	ribonuclease III activity
H7F26_15390	COG1196	nuclear chromosome segregation
H7F26_15395	COG0552	protein localization to endoplasmic reticulum
H7F26_15400	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H7F26_15405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7F26_15410	COG0228	four-way junction DNA binding
H7F26_15415	COG1837	Belongs to the UPF0109 family
H7F26_15425	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7F26_15430	COG0336	Belongs to the RNA methyltransferase TrmD family
H7F26_15435	COG0335	large ribosomal subunit rRNA binding
H7F26_15440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F26_15445	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F26_15455	COG2257	FlhB HrpN YscU SpaS Family
H7F26_15460	COG0045	succinate-CoA ligase (ADP-forming) activity
H7F26_15465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F26_15470	COG0758	DNA mediated transformation
H7F26_15475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F26_15480	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H7F26_15485	COG4974	Belongs to the 'phage' integrase family
H7F26_15490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H7F26_15495	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H7F26_15500	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7F26_15505	COG1815	bacterial-type flagellum-dependent cell motility
H7F26_15510	COG1558	bacterial-type flagellum-dependent cell motility
H7F26_15515	COG1677	Flagellar hook-basal body complex protein FliE
H7F26_15520	COG1766	The M ring may be actively involved in energy transduction
H7F26_15525	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F26_15530	COG1317	bacterial-type flagellum organization
H7F26_15535	COG1157	protein secretion by the type III secretion system
H7F26_15540	COG2882	bacterial-type flagellum organization
H7F26_15550	COG3144	bacterial-type flagellum assembly
H7F26_15555	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H7F26_15560	COG4786	Flagellar basal body rod
H7F26_15565	COG1582	Flagellar protein (FlbD)
H7F26_15570	COG1580	Controls the rotational direction of flagella during chemotaxis
H7F26_15575	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F26_15580	COG1776	CheC inhibitor of MCP methylation
H7F26_15580	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F26_15585	COG2201	protein-glutamate methylesterase activity
H7F26_15590	COG3190	flagellar
H7F26_15595	COG1338	Plays a role in the flagellum-specific transport system
H7F26_15600	COG1987	bacterial-type flagellum assembly
H7F26_15605	COG1684	flagellar biosynthetic protein fliR
H7F26_15610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F26_15615	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F26_15620	COG1419	protein localization to endoplasmic reticulum
H7F26_15625	COG0455	bacterial-type flagellum organization
H7F26_15630	COG2201	protein-glutamate methylesterase activity
H7F26_15635	COG0643	Histidine kinase
H7F26_15635	COG2198	Histidine kinase
H7F26_15640	COG0835	chemotaxis
H7F26_15645	COG1776	CheC inhibitor of MCP methylation
H7F26_15650	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
H7F26_15655	COG1191	sigma factor activity
H7F26_15665	COG0052	Belongs to the universal ribosomal protein uS2 family
H7F26_15670	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H7F26_15675	COG0528	UMP kinase activity
H7F26_15680	COG0233	cytoplasmic translational termination
H7F26_15685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7F26_15690	COG4589	Belongs to the CDS family
H7F26_15695	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H7F26_15700	COG0750	zinc metalloprotease
H7F26_15705	COG0442	prolyl-tRNA aminoacylation
H7F26_15710	COG2176	DNA-directed DNA polymerase activity
H7F26_15735	COG0779	Required for maturation of 30S ribosomal subunits
H7F26_15740	COG0195	Participates in both transcription termination and antitermination
H7F26_15745	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H7F26_15750	COG1358	cellular component organization or biogenesis
H7F26_15755	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H7F26_15760	COG1550	Protein conserved in bacteria
H7F26_15765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H7F26_15770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7F26_15775	COG0196	riboflavin kinase activity
H7F26_15780	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H7F26_15785	COG1185	polyribonucleotide nucleotidyltransferase activity
H7F26_15790	COG0726	polysaccharide deacetylase
H7F26_15795	COG0612	Peptidase, M16
H7F26_15800	COG1873	PFAM PRC-barrel domain
H7F26_15805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F26_15810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F26_15815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7F26_15820	COG0527	aspartate kinase activity
H7F26_15830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H7F26_15835	COG0740	serine-type endopeptidase activity
H7F26_15845	COG1674	ftsk spoiiie
H7F26_15845	COG4980	gas vesicle protein
H7F26_15850	COG2188	Transcriptional regulator
H7F26_15855	COG2814	Major facilitator Superfamily
H7F26_15860	COG0612	Peptidase, M16
H7F26_15865	COG0612	Peptidase, M16
H7F26_15870	COG0300	oxidoreductase activity
H7F26_15885	COG1426	Protein conserved in bacteria
H7F26_15890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7F26_15895	COG1546	Belongs to the CinA family
H7F26_15895	COG1058	Belongs to the CinA family
H7F26_15905	COG1418	mRNA catabolic process
H7F26_15910	COG1692	metallophosphoesterase
H7F26_15915	COG2359	stage V sporulation protein S
H7F26_15925	COG1063	alcohol dehydrogenase
H7F26_15930	COG0156	8-amino-7-oxononanoate synthase activity
H7F26_15935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F26_15940	COG4550	Control of competence regulator ComK, YlbF/YmcA
H7F26_15950	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H7F26_15955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7F26_15960	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7F26_15965	COG5444	nuclease activity
H7F26_15980	COG0523	cobalamin synthesis protein
H7F26_15990	COG1247	-acetyltransferase
H7F26_16005	COG1231	oxidoreductase activity
H7F26_16010	COG3619	membrane
H7F26_16015	COG3263	regulation of cellular component size
H7F26_16035	COG0393	Putative heavy-metal-binding
H7F26_16040	COG0398	Pfam SNARE associated Golgi protein
H7F26_16045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F26_16050	COG1819	glycosyl
H7F26_16055	COG0531	amino acid
H7F26_16060	COG5577	PFAM Coat F domain
H7F26_16070	COG1388	LysM domain
H7F26_16070	COG3858	chitin binding
H7F26_16075	COG1309	transcriptional regulator
H7F26_16080	COG3631	Ketosteroid isomerase-related protein
H7F26_16085	COG0702	epimerase
H7F26_16095	COG1764	response to oxidative stress
H7F26_16100	COG2076	Multidrug Resistance protein
H7F26_16105	COG2076	Multidrug Resistance protein
H7F26_16120	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H7F26_16125	COG1923	regulation of RNA biosynthetic process
H7F26_16135	COG1780	Probably involved in ribonucleotide reductase function
H7F26_16140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F26_16145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F26_16150	COG4112	unkown
H7F26_16165	COG0735	belongs to the Fur family
H7F26_16170	COG1802	Transcriptional regulator
H7F26_16175	COG0697	spore germination
H7F26_16210	COG1309	transcriptional regulator
H7F26_16245	COG4282	regulation of fungal-type cell wall biogenesis
H7F26_16270	COG0464	growth
H7F26_16275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7F26_16280	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H7F26_16285	COG0789	Transcriptional regulator
H7F26_16290	COG0174	glutamine synthetase
H7F26_16325	COG1073	alpha beta
H7F26_16370	COG1309	transcriptional regulator
H7F26_16375	COG2076	Multidrug Resistance protein
H7F26_16380	COG2076	Multidrug Resistance protein
H7F26_16405	COG3546	catalase activity
H7F26_16430	COG1846	Transcriptional regulator
H7F26_16435	COG0778	Nitroreductase
H7F26_16440	COG0346	lactoylglutathione lyase activity
H7F26_16445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F26_16450	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7F26_16475	COG3209	COG3209 Rhs family protein
H7F26_16480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F26_16485	COG1388	LysM domain
H7F26_16490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7F26_16495	COG4224	UPF0291 protein
H7F26_16500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7F26_16510	COG3763	UPF0154 protein
H7F26_16520	COG0785	Cytochrome C biogenesis protein
H7F26_16525	COG2201	protein-glutamate methylesterase activity
H7F26_16530	COG4846	Membrane protein involved in cytochrome C biogenesis
H7F26_16540	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F26_16555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7F26_16560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_16580	COG0824	Thioesterase
H7F26_16600	COG4841	protein insertion into membrane
H7F26_16605	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H7F26_16610	COG1832	CoA-binding protein
H7F26_16615	COG0187	DNA topoisomerase II activity
H7F26_16620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7F26_16625	COG1609	Transcriptional regulator
H7F26_16640	COG2160	L-arabinose isomerase activity
H7F26_16660	COG1115	amino acid carrier protein
H7F26_16670	COG2181	nitrate reductase activity
H7F26_16675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H7F26_16680	COG1140	nitrate reductase beta subunit
H7F26_16685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H7F26_16700	COG0535	radical SAM domain protein
H7F26_16705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F26_16715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F26_16720	COG2223	nitrite transmembrane transporter activity
H7F26_16740	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
H7F26_16750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H7F26_16760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F26_16775	COG3420	alginic acid biosynthetic process
H7F26_16780	COG1114	Component of the transport system for branched-chain amino acids
H7F26_16790	COG0789	Transcriptional regulator
H7F26_16815	COG1024	Enoyl-CoA hydratase
H7F26_16820	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_16825	COG2084	Dehydrogenase
H7F26_16830	COG1960	acyl-CoA dehydrogenase activity
H7F26_16835	COG1482	cell wall glycoprotein biosynthetic process
H7F26_16840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_16840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_16840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_16860	COG3711	transcriptional antiterminator
H7F26_16860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_16875	COG1725	Transcriptional regulator
H7F26_16880	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_16885	COG1312	Catalyzes the dehydration of D-mannonate
H7F26_16900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H7F26_16910	COG1609	Transcriptional regulator
H7F26_16915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F26_16920	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7F26_16925	COG0640	Transcriptional regulator
H7F26_16930	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
H7F26_16945	COG1649	PFAM Uncharacterised BCR, COG1649
H7F26_16950	COG2404	hydrolase activity, acting on ester bonds
H7F26_16955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H7F26_16965	COG2027	D-alanyl-D-alanine carboxypeptidase
H7F26_16970	COG1252	NADH dehydrogenase
H7F26_16980	COG0166	Belongs to the GPI family
H7F26_16990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F26_16995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F26_17000	COG1024	Enoyl-CoA hydratase
H7F26_17005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F26_17010	COG0511	ligase activity, forming carbon-carbon bonds
H7F26_17015	COG0439	Biotin carboxylase
H7F26_17020	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_17025	COG1960	acyl-CoA dehydrogenase activity
H7F26_17030	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F26_17035	COG1733	regulation of RNA biosynthetic process
H7F26_17040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F26_17045	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F26_17055	COG2323	membrane
H7F26_17065	COG0306	phosphate transporter
H7F26_17070	COG0175	sulfate reduction
H7F26_17075	COG1809	phosphosulfolactate synthase activity
H7F26_17080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_17085	COG4948	Mandelate Racemase Muconate Lactonizing
H7F26_17090	COG2814	Major facilitator Superfamily
H7F26_17095	COG0463	Glycosyl transferase, family 2
H7F26_17105	COG0493	'glutamate synthase
H7F26_17110	COG0069	glutamate synthase activity
H7F26_17110	COG0067	glutamate synthase
H7F26_17110	COG0070	glutamate synthase
H7F26_17115	COG0583	DNA-binding transcription factor activity
H7F26_17135	COG1846	Transcriptional regulator
H7F26_17145	COG1132	(ABC) transporter
H7F26_17155	COG0300	oxidoreductase activity
H7F26_17160	COG3848	Pyruvate phosphate dikinase
H7F26_17160	COG0574	Belongs to the PEP-utilizing enzyme family
H7F26_17165	COG0477	Major facilitator Superfamily
H7F26_17170	COG0243	molybdopterin cofactor binding
H7F26_17175	COG1846	Transcriptional regulator
H7F26_17185	COG0531	amino acid
H7F26_17195	COG0531	amino acid
H7F26_17200	COG0531	amino acid
H7F26_17205	COG0697	spore germination
H7F26_17210	COG0488	(ABC) transporter
H7F26_17215	COG0840	transmembrane signaling receptor activity
H7F26_17220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F26_17225	COG1404	Belongs to the peptidase S8 family
H7F26_17235	COG1309	transcriptional regulator
H7F26_17240	COG1846	Transcriptional regulator
H7F26_17270	COG1309	transcriptional regulator
H7F26_17275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_17280	COG3708	Transcriptional regulator
H7F26_17290	COG2378	regulation of single-species biofilm formation
H7F26_17300	COG0640	Transcriptional regulator
H7F26_17305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_17315	COG0531	amino acid
H7F26_17320	COG0741	lytic transglycosylase activity
H7F26_17325	COG1086	Polysaccharide biosynthesis protein
H7F26_17345	COG2322	membrane
H7F26_17360	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_17365	COG1388	LysM domain
H7F26_17365	COG3584	3D domain protein
H7F26_17370	COG0514	ATP-dependent DNA helicase (RecQ)
H7F26_17390	COG2315	Protein conserved in bacteria
H7F26_17405	COG0402	S-adenosylhomocysteine deaminase activity
H7F26_17420	COG2267	carboxylic ester hydrolase activity
H7F26_17435	COG1280	lysine exporter protein (LysE YggA)
H7F26_17440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F26_17450	COG0574	Belongs to the PEP-utilizing enzyme family
H7F26_17450	COG3848	Pyruvate phosphate dikinase
H7F26_17455	COG1309	transcriptional regulator
H7F26_17470	COG2318	DinB family
H7F26_17475	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F26_17480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F26_17495	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_17500	COG2814	Major facilitator Superfamily
H7F26_17515	COG1657	PFAM Prenyltransferase squalene oxidase
H7F26_17520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F26_17530	COG0733	neurotransmitter:sodium symporter activity
H7F26_17535	COG0385	Bile acid
H7F26_17540	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F26_17545	COG0567	Dehydrogenase, E1 component
H7F26_17550	COG4548	von Willebrand factor, type A
H7F26_17555	COG0714	Associated with various cellular activities
H7F26_17560	COG2032	superoxide dismutase activity
H7F26_17565	COG1388	LysM domain
H7F26_17565	COG0791	NLP P60 protein
H7F26_17570	COG0534	Mate efflux family protein
H7F26_17575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F26_17580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F26_17590	COG2962	Rard protein
H7F26_17600	COG4305	rare lipoprotein A
H7F26_17610	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_17615	COG1733	regulation of RNA biosynthetic process
H7F26_17620	COG0778	Nitroreductase
H7F26_17625	COG0400	carboxylic ester hydrolase activity
H7F26_17635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_17645	COG0793	Belongs to the peptidase S41A family
H7F26_17645	COG3409	Peptidoglycan-binding domain 1 protein
H7F26_17650	COG2226	methyltransferase
H7F26_17660	COG1876	peptidase activity
H7F26_17665	COG0813	purine-nucleoside phosphorylase activity
H7F26_17670	COG0701	Predicted permease
H7F26_17690	COG0671	phosphoesterase, PA-phosphatase related
H7F26_17705	COG4479	Belongs to the UPF0346 family
H7F26_17715	COG1509	lysine 2,3-aminomutase activity
H7F26_17720	COG0456	acetyltransferase
H7F26_17725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F26_17730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7F26_17735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7F26_17740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F26_17755	COG0456	acetyltransferase
H7F26_17760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F26_17765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F26_17770	COG1846	Transcriptional regulator
H7F26_17780	COG3706	GGDEF domain
H7F26_17785	COG0534	Mate efflux family protein
H7F26_17800	COG4698	Protein conserved in bacteria
H7F26_17805	COG2755	lipolytic protein G-D-S-L family
H7F26_17810	COG1999	signal sequence binding
H7F26_17825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F26_17830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7F26_17835	COG1272	protein, Hemolysin III
H7F26_17840	COG0204	Acyl-transferase
H7F26_17845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7F26_17850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F26_17860	COG2136	Putative SAM-dependent methyltransferase
H7F26_17860	COG2521	methyltransferase
H7F26_17870	COG0129	dihydroxy-acid dehydratase activity
H7F26_17875	COG1413	lyase activity
H7F26_17880	COG1418	mRNA catabolic process
H7F26_17885	COG0386	Belongs to the glutathione peroxidase family
H7F26_17890	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H7F26_17895	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H7F26_17900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F26_17910	COG1278	Cold shock
H7F26_17930	COG0328	RNA-DNA hybrid ribonuclease activity
H7F26_17935	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H7F26_17940	COG0328	RNA-DNA hybrid ribonuclease activity
H7F26_17950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F26_17965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F26_17975	COG1755	Isoprenylcysteine carboxyl methyltransferase
H7F26_17980	COG3424	synthase
H7F26_17985	COG0456	acetyltransferase
H7F26_17990	COG2233	PERMEase
H7F26_17995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F26_18000	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H7F26_18005	COG1199	ATP-dependent helicase activity
H7F26_18020	COG0116	Belongs to the methyltransferase superfamily
H7F26_18030	COG3599	regulation of cell shape
H7F26_18035	COG4474	Belongs to the UPF0398 family
H7F26_18045	COG3359	exonuclease
H7F26_18050	COG1111	helicase
H7F26_18050	COG1205	dead DEAH box helicase
H7F26_18055	COG2190	(PTS) system
H7F26_18060	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F26_18100	COG3331	DNA recombination
H7F26_18105	COG4499	WXG100 protein secretion system (Wss), protein YukC
H7F26_18105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F26_18115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7F26_18120	COG3935	DnaD domain protein
H7F26_18125	COG0017	Asparaginyl-tRNA synthetase
H7F26_18130	COG0436	Aminotransferase
H7F26_18135	COG5353	protein conserved in bacteria
H7F26_18145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7F26_18145	COG1199	ATP-dependent helicase activity
H7F26_18150	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H7F26_18155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H7F26_18160	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H7F26_18170	COG0617	tRNA 3'-terminal CCA addition
H7F26_18175	COG0438	transferase activity, transferring glycosyl groups
H7F26_18180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F26_18185	COG1803	Methylglyoxal synthase
H7F26_18190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H7F26_18195	COG1694	Mazg nucleotide pyrophosphohydrolase
H7F26_18200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_18210	COG4347	Protein of unknown function (DUF1405)
H7F26_18220	COG2010	Cytochrome c
H7F26_18220	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F26_18225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F26_18230	COG0723	plastoquinol--plastocyanin reductase activity
H7F26_18240	COG5582	Belongs to the UPF0302 family
H7F26_18245	COG0457	Tetratricopeptide repeat
H7F26_18250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7F26_18255	COG0287	Prephenate dehydrogenase
H7F26_18260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F26_18265	COG0159	tryptophan synthase activity
H7F26_18270	COG0133	tryptophan synthase activity
H7F26_18275	COG0135	phosphoribosylanthranilate isomerase activity
H7F26_18280	COG0134	indole-3-glycerol-phosphate synthase activity
H7F26_18285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F26_18290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7F26_18295	COG4401	Chorismate mutase type I
H7F26_18300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H7F26_18305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H7F26_18310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H7F26_18315	COG0105	UTP biosynthetic process
H7F26_18320	COG0142	geranyltranstransferase activity
H7F26_18325	COG2226	methyltransferase
H7F26_18330	COG0142	geranyltranstransferase activity
H7F26_18345	COG0776	regulation of translation
H7F26_18350	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F26_18365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H7F26_18370	COG1160	GTP binding
H7F26_18395	COG1304	FMN binding
H7F26_18400	COG0539	negative regulation of cytoplasmic translation
H7F26_18405	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H7F26_18415	COG2959	enzyme of heme biosynthesis
H7F26_18420	COG3409	Peptidoglycan-binding domain 1 protein
H7F26_18420	COG3773	Cell wall hydrolase
H7F26_18425	COG2339	peptidase activity
H7F26_18435	COG0492	ferredoxin-NADP+ reductase activity
H7F26_18440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F26_18445	COG4862	establishment of competence for transformation
H7F26_18450	COG1408	metallophosphoesterase
H7F26_18460	COG1388	LysM domain
H7F26_18465	COG1266	CAAX protease self-immunity
H7F26_18470	COG0514	ATP-dependent DNA helicase (RecQ)
H7F26_18475	COG4955	Helix-turn-helix domain
H7F26_18480	COG1141	Ferredoxin
H7F26_18485	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H7F26_18490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F26_18495	COG0739	heme binding
H7F26_18505	COG1595	DNA-templated transcription, initiation
H7F26_18510	COG1316	TRANSCRIPTIONal
H7F26_18525	COG5002	protein histidine kinase activity
H7F26_18530	COG0745	RESPONSE REGULATOR receiver
H7F26_18535	COG5002	protein histidine kinase activity
H7F26_18540	COG0745	RESPONSE REGULATOR receiver
H7F26_18545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F26_18550	COG1333	cytochrome c biogenesis protein
H7F26_18555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_18560	COG1187	pseudouridine synthase activity
H7F26_18565	COG0700	Nucleoside recognition
H7F26_18570	COG2715	membrane protein required for spore maturation
H7F26_18575	COG1686	Belongs to the peptidase S11 family
H7F26_18585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7F26_18590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H7F26_18600	COG1547	Domain of unknown function (DUF309)
H7F26_18605	COG0456	acetyltransferase
H7F26_18610	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H7F26_18615	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F26_18615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F26_18620	COG0307	riboflavin synthase, alpha
H7F26_18625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F26_18625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F26_18650	COG0457	Tetratricopeptide repeat
H7F26_18655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7F26_18660	COG4086	secreted protein
H7F26_18665	COG4195	phage-related replication protein
H7F26_18670	COG0019	diaminopimelate decarboxylase activity
H7F26_18680	COG0697	spore germination
H7F26_18695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F26_18730	COG1686	Belongs to the peptidase S11 family
H7F26_18735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H7F26_18740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H7F26_18745	COG4974	Belongs to the 'phage' integrase family
H7F26_18755	COG0735	belongs to the Fur family
H7F26_18760	COG1300	Membrane
H7F26_18765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_18785	COG2153	protein acetylation
H7F26_18790	COG1379	DNA repair
H7F26_18795	COG0494	nUDIX hydrolase
H7F26_18805	COG1309	transcriptional regulator
H7F26_18815	COG0667	Aldo Keto reductase
H7F26_18825	COG1073	alpha beta
H7F26_18835	COG4918	Iron-sulphur cluster biosynthesis
H7F26_18850	COG2329	Antibiotic biosynthesis monooxygenase
H7F26_18855	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H7F26_18865	COG0747	negative chemotaxis
H7F26_18870	COG0601	transmembrane transport
H7F26_18880	COG0444	Belongs to the ABC transporter superfamily
H7F26_18890	COG0534	Mate efflux family protein
H7F26_18905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F26_18915	COG2211	Major facilitator Superfamily
H7F26_18920	COG0346	lactoylglutathione lyase activity
H7F26_18925	COG1072	(Pantothenic acid kinase))
H7F26_18935	COG1131	(ABC) transporter
H7F26_18955	COG4195	phage-related replication protein
H7F26_18960	COG0300	oxidoreductase activity
H7F26_18965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_18970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F26_18975	COG4187	Peptidase family M20/M25/M40
H7F26_18980	COG1902	pentaerythritol trinitrate reductase activity
H7F26_18985	COG0596	Alpha beta hydrolase
H7F26_18990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F26_18995	COG1234	tRNA 3'-trailer cleavage
H7F26_19000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H7F26_19015	COG2358	TRAP transporter, solute receptor (TAXI family
H7F26_19020	COG2188	Transcriptional regulator
H7F26_19025	COG2723	6-phospho-beta-galactosidase activity
H7F26_19030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_19035	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F26_19040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_19045	COG1785	Belongs to the alkaline phosphatase family
H7F26_19050	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_19055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H7F26_19060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F26_19070	COG0706	membrane insertase activity
H7F26_19075	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7F26_19080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F26_19090	COG4129	membrane
H7F26_19095	COG1126	abc transporter atp-binding protein
H7F26_19100	COG0765	amino acid transport
H7F26_19105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F26_19120	COG1597	lipid kinase activity
H7F26_19125	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F26_19130	COG0022	dehydrogenase e1 component
H7F26_19135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F26_19140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F26_19145	COG3426	butyrate kinase activity
H7F26_19155	COG0280	phosphate acetyltransferase
H7F26_19160	COG3829	transcription factor binding
H7F26_19160	COG3290	protein histidine kinase activity
H7F26_19170	COG0584	glycerophosphoryl diester phosphodiesterase
H7F26_19175	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_19190	COG1045	serine acetyltransferase
H7F26_19200	COG0745	RESPONSE REGULATOR receiver
H7F26_19205	COG0750	zinc metalloprotease
H7F26_19210	COG0497	DNA recombination
H7F26_19215	COG1438	arginine binding
H7F26_19220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H7F26_19225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H7F26_19230	COG0142	geranyltranstransferase activity
H7F26_19235	COG1722	exodeoxyribonuclease VII activity
H7F26_19240	COG1570	exodeoxyribonuclease VII activity
H7F26_19245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H7F26_19250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F26_19255	COG1302	Protein conserved in bacteria
H7F26_19260	COG0439	Biotin carboxylase
H7F26_19265	COG0511	ligase activity, forming carbon-carbon bonds
H7F26_19305	COG3854	ATPases associated with a variety of cellular activities
H7F26_19315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H7F26_19320	COG0006	proline dipeptidase activity
H7F26_19325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H7F26_19335	COG3872	metal-dependent enzyme
H7F26_19345	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7F26_19350	COG1321	iron dependent repressor
H7F26_19355	COG0095	Lipoate-protein ligase
H7F26_19360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F26_19365	COG2113	Glycine betaine
H7F26_19370	COG4176	ABC-type proline glycine betaine transport system permease component
H7F26_19375	COG4175	Glycine betaine
H7F26_19375	COG0517	IMP dehydrogenase activity
H7F26_19380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F26_19385	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F26_19390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H7F26_19395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7F26_19420	COG0681	Belongs to the peptidase S26 family
H7F26_19445	COG4940	Competence protein ComGF
H7F26_19455	COG4970	Tfp pilus assembly protein FimT
H7F26_19460	COG4537	Required for transformation and DNA binding
H7F26_19465	COG1459	type II secretion system
H7F26_19470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7F26_19475	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F26_19485	COG1393	Belongs to the ArsC family
H7F26_19495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_19505	COG0011	TIGRFAM Protein of
H7F26_19515	COG2866	Carboxypeptidase
H7F26_19520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_19530	COG1368	sulfuric ester hydrolase activity
H7F26_19535	COG1940	carbohydrate kinase activity
H7F26_19540	COG4483	Protein conserved in bacteria
H7F26_19545	COG0697	spore germination
H7F26_19550	COG0457	Tetratricopeptide repeat
H7F26_19550	COG0705	Rhomboid family
H7F26_19560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7F26_19565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F26_19570	COG0438	transferase activity, transferring glycosyl groups
H7F26_19585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F26_19590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F26_19595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F26_19600	COG0581	inorganic phosphate transmembrane transporter activity
H7F26_19605	COG0573	inorganic phosphate transmembrane transporter activity
H7F26_19610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7F26_19615	COG0768	penicillin binding
H7F26_19620	COG0477	Major facilitator Superfamily
H7F26_19625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F26_19630	COG2839	Protein conserved in bacteria
H7F26_19635	COG5521	maltodextrose utilization protein MalA
H7F26_19640	COG1388	LysM domain
H7F26_19645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H7F26_19650	COG4709	membrane
H7F26_19655	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
H7F26_19660	COG0735	belongs to the Fur family
H7F26_19665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F26_19670	COG1121	(ABC) transporter
H7F26_19675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_19685	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H7F26_19690	COG0513	Belongs to the DEAD box helicase family
H7F26_19700	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H7F26_19705	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7F26_19710	COG2384	SAM-dependent methyltransferase
H7F26_19755	COG5444	nuclease activity
H7F26_19770	COG2010	Cytochrome c
H7F26_19775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7F26_19780	COG0358	DNA primase activity
H7F26_19785	COG1671	Belongs to the UPF0178 family
H7F26_19790	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H7F26_19795	COG0517	IMP dehydrogenase activity
H7F26_19800	COG0751	glycine-tRNA ligase activity
H7F26_19805	COG0752	glycyl-tRNA synthetase alpha subunit
H7F26_19810	COG1381	Involved in DNA repair and RecF pathway recombination
H7F26_19820	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7F26_19825	COG0295	cytidine deaminase activity
H7F26_19830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H7F26_19835	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H7F26_19840	COG1480	7TM receptor with intracellular HD hydrolase
H7F26_19845	COG1702	phosphate starvation-inducible protein PhoH
H7F26_19850	COG0561	phosphatase activity
H7F26_19865	COG4864	UPF0365 protein
H7F26_19870	COG1030	water channel activity
H7F26_19875	COG1610	YqeY-like protein
H7F26_19880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H7F26_19885	COG1283	sodium-dependent phosphate transmembrane transporter activity
H7F26_19890	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H7F26_19895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F26_19900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7F26_19905	COG2264	protein methyltransferase activity
H7F26_19910	COG0484	heat shock protein binding
H7F26_19915	COG0443	Heat shock 70 kDa protein
H7F26_19920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H7F26_19925	COG1420	regulation of RNA biosynthetic process
H7F26_19930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F26_19935	COG0481	GTPase activity
H7F26_19945	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_19950	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H7F26_19955	COG0268	Binds directly to 16S ribosomal RNA
H7F26_19960	COG1466	dna polymerase III delta subunit
H7F26_19970	COG0658	competence protein
H7F26_19970	COG2333	competence protein COMEC
H7F26_19975	COG2131	deaminase
H7F26_19980	COG1555	photosystem II stabilization
H7F26_19980	COG1596	polysaccharide export
H7F26_19985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F26_19990	COG2226	methyltransferase
H7F26_19995	COG0799	negative regulation of ribosome biogenesis
H7F26_20000	COG1713	HD superfamily hydrolase involved in NAD metabolism
H7F26_20005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H7F26_20010	COG1534	Rna-binding protein
H7F26_20015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F26_20020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F26_20025	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H7F26_20040	COG2755	lipolytic protein G-D-S-L family
H7F26_20045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F26_20050	COG5609	conserved protein (DUF2294)
H7F26_20055	COG3383	formate dehydrogenase (NAD+) activity
H7F26_20060	COG2427	Protein of unknown function (DUF1641)
H7F26_20090	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_20135	COG1136	(ABC) transporter
H7F26_20140	COG0577	efflux transmembrane transporter activity
H7F26_20220	COG2197	response regulator
H7F26_20225	COG4585	Histidine kinase
H7F26_20230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_20235	COG0730	response to heat
H7F26_20240	COG0425	Belongs to the sulfur carrier protein TusA family
H7F26_20250	COG0425	Belongs to the sulfur carrier protein TusA family
H7F26_20250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F26_20255	COG2210	Belongs to the sulfur carrier protein TusA family
H7F26_20260	COG1937	Protein conserved in bacteria
H7F26_20305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7F26_20310	COG0113	porphobilinogen synthase activity
H7F26_20315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H7F26_20320	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H7F26_20325	COG1733	regulation of RNA biosynthetic process
H7F26_20330	COG3239	Fatty acid desaturase
H7F26_20335	COG4585	Histidine kinase
H7F26_20340	COG2197	response regulator
H7F26_20345	COG0492	ferredoxin-NADP+ reductase activity
H7F26_20350	COG0747	negative chemotaxis
H7F26_20355	COG0601	transmembrane transport
H7F26_20360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F26_20365	COG0444	Belongs to the ABC transporter superfamily
H7F26_20370	COG4608	Belongs to the ABC transporter superfamily
H7F26_20390	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_20405	COG2124	cytochrome p450
H7F26_20410	COG0730	response to heat
H7F26_20420	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_20425	COG1621	beta-fructofuranosidase activity
H7F26_20430	COG3716	PTS system mannose fructose sorbose family IID component
H7F26_20435	COG3715	PTS system
H7F26_20440	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_20445	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_20450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7F26_20450	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H7F26_20475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7F26_20480	COG0656	L-ascorbic acid biosynthetic process
H7F26_20485	COG2814	Major facilitator Superfamily
H7F26_20490	COG1733	regulation of RNA biosynthetic process
H7F26_20495	COG3340	Belongs to the peptidase S51 family
H7F26_20500	COG1587	Uroporphyrinogen-III synthase
H7F26_20510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_20515	COG0583	DNA-binding transcription factor activity
H7F26_20520	COG2814	Major facilitator Superfamily
H7F26_20530	COG2124	cytochrome p450
H7F26_20530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F26_20535	COG1309	transcriptional regulator
H7F26_20540	COG1404	Belongs to the peptidase S8 family
H7F26_20545	COG2226	methyltransferase
H7F26_20570	COG0626	cystathionine gamma-synthase activity
H7F26_20575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F26_20580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7F26_20585	COG2226	methyltransferase
H7F26_20600	COG0768	penicillin binding
H7F26_20605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7F26_20610	COG0572	uridine kinase
H7F26_20615	COG0826	peptidase U32
H7F26_20620	COG0826	peptidase U32
H7F26_20625	COG4122	O-methyltransferase activity
H7F26_20630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F26_20635	COG3906	Belongs to the UPF0473 family
H7F26_20640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7F26_20645	COG4472	Bacterial protein of unknown function (DUF965)
H7F26_20650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7F26_20655	COG0628	permease
H7F26_20670	COG3881	PFAM PRC-barrel domain
H7F26_20675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7F26_20680	COG0457	Tetratricopeptide repeat
H7F26_20685	COG0482	sulfurtransferase activity
H7F26_20690	COG1104	cysteine desulfurase activity
H7F26_20695	COG1959	2 iron, 2 sulfur cluster binding
H7F26_20700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7F26_20705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7F26_20715	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H7F26_20720	COG0124	histidyl-tRNA synthetase
H7F26_20730	COG4991	sh3 domain protein
H7F26_20730	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_20730	COG3103	Sh3 type 3 domain protein
H7F26_20735	COG1490	D-aminoacyl-tRNA deacylase activity
H7F26_20740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7F26_20745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F26_20750	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H7F26_20750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7F26_20755	COG5416	Lipopolysaccharide assembly protein A domain
H7F26_20760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F26_20760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F26_20770	COG2244	polysaccharide biosynthetic process
H7F26_20775	COG2323	membrane
H7F26_20785	COG1862	Preprotein translocase
H7F26_20790	COG0343	queuine tRNA-ribosyltransferase activity
H7F26_20795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H7F26_20805	COG2255	four-way junction helicase activity
H7F26_20810	COG0632	four-way junction helicase activity
H7F26_20820	COG2112	serine threonine protein kinase
H7F26_20830	COG2318	DinB family
H7F26_20835	COG4195	phage-related replication protein
H7F26_20850	COG0217	transcriptional regulatory protein
H7F26_20860	COG1388	LysM domain
H7F26_20865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7F26_20870	COG0157	Belongs to the NadC ModD family
H7F26_20875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H7F26_20880	COG1104	cysteine desulfurase activity
H7F26_20885	COG1827	regulation of RNA biosynthetic process
H7F26_20890	COG0077	Prephenate dehydratase
H7F26_20895	COG4492	Belongs to the UPF0735 family
H7F26_20900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H7F26_20905	COG3290	protein histidine kinase activity
H7F26_20910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H7F26_20915	COG2868	ribosomal protein
H7F26_20920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H7F26_20925	COG1994	Peptidase M50
H7F26_20930	COG0739	heme binding
H7F26_20935	COG3832	glyoxalase III activity
H7F26_20940	COG0640	Transcriptional regulator
H7F26_20945	COG2894	cell division
H7F26_20950	COG0850	regulation of cytokinetic process
H7F26_20955	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H7F26_20965	COG1077	Cell shape determining protein MreB Mrl
H7F26_20970	COG2003	Belongs to the UPF0758 family
H7F26_20975	COG0424	maF-like protein
H7F26_20985	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H7F26_20990	COG0285	dihydrofolate synthase activity
H7F26_20995	COG0525	valine-tRNA ligase activity
H7F26_21005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F26_21010	COG1388	LysM domain
H7F26_21015	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F26_21020	COG0113	porphobilinogen synthase activity
H7F26_21025	COG1587	Uroporphyrinogen-III synthase
H7F26_21030	COG0181	hydroxymethylbilane synthase activity
H7F26_21035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F26_21040	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H7F26_21050	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H7F26_21055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7F26_21060	COG0470	DNA polymerase III
H7F26_21060	COG1067	ATP-dependent peptidase activity
H7F26_21065	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H7F26_21070	COG0544	peptidyl-prolyl cis-trans isomerase activity
H7F26_21075	COG0457	Tetratricopeptide repeat
H7F26_21075	COG1477	protein flavinylation
H7F26_21080	COG0066	3-isopropylmalate dehydratase activity
H7F26_21085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7F26_21090	COG0473	3-isopropylmalate dehydrogenase activity
H7F26_21095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F26_21100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H7F26_21105	COG0440	acetolactate synthase activity
H7F26_21110	COG0028	Belongs to the TPP enzyme family
H7F26_21115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F26_21125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F26_21145	COG1783	phage Terminase large subunit
H7F26_21180	COG5444	nuclease activity
H7F26_21185	COG0457	Tetratricopeptide repeat
H7F26_21210	COG0622	Phosphoesterase
H7F26_21215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H7F26_21220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H7F26_21225	COG5401	PFAM Sporulation and spore germination
H7F26_21230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7F26_21235	COG1846	Transcriptional regulator
H7F26_21240	COG2197	response regulator
H7F26_21245	COG4221	oxidoreductase activity
H7F26_21250	COG0824	Thioesterase
H7F26_21255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7F26_21260	COG1053	succinate dehydrogenase
H7F26_21265	COG2009	succinate dehydrogenase
H7F26_21270	COG1719	4-vinyl reductase, 4VR
H7F26_21275	COG0527	aspartate kinase activity
H7F26_21280	COG0322	excinuclease ABC activity
H7F26_21285	COG3118	belongs to the thioredoxin family
H7F26_21290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H7F26_21295	COG2086	electron transfer activity
H7F26_21300	COG1024	Enoyl-CoA hydratase
H7F26_21305	COG1309	transcriptional regulator
H7F26_21310	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_21315	COG3766	membrane
H7F26_21320	COG1193	negative regulation of DNA recombination
H7F26_21325	COG1796	DNA polymerase
H7F26_21325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7F26_21330	COG1286	toxin biosynthetic process
H7F26_21335	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
H7F26_21340	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F26_21360	COG1137	ATPase activity
H7F26_21375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F26_21375	COG0072	phenylalanine-tRNA ligase activity
H7F26_21380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H7F26_21385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F26_21395	COG1966	Carbon starvation protein
H7F26_21410	COG0395	ABC-type sugar transport system, permease component
H7F26_21415	COG1175	transmembrane transport
H7F26_21420	COG1653	transport
H7F26_21425	COG0371	Dehydrogenase
H7F26_21430	COG0235	Class ii aldolase
H7F26_21435	COG1069	ribulokinase activity
H7F26_21440	COG2160	L-arabinose isomerase activity
H7F26_21445	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F26_21450	COG1363	Peptidase, m42
H7F26_21460	COG3326	Membrane
H7F26_21465	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H7F26_21470	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H7F26_21475	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H7F26_21480	COG1346	cytolysis
H7F26_21490	COG3540	Alkaline phosphatase
H7F26_21495	COG3279	Response regulator of the LytR AlgR family
H7F26_21500	COG3275	phosphorelay sensor kinase activity
H7F26_21510	COG1011	Hydrolase
H7F26_21515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F26_21525	COG0398	Pfam SNARE associated Golgi protein
H7F26_21530	COG1484	DNA-dependent DNA replication
H7F26_21535	COG3611	Membrane attachment protein
H7F26_21540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H7F26_21550	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H7F26_21555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F26_21560	COG3866	Pectate lyase
H7F26_21565	COG0237	dephospho-CoA kinase activity
H7F26_21570	COG1971	Probably functions as a manganese efflux pump
H7F26_21575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H7F26_21580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F26_21580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F26_21585	COG5002	protein histidine kinase activity
H7F26_21590	COG0745	RESPONSE REGULATOR receiver
H7F26_21595	COG0039	L-malate dehydrogenase activity
H7F26_21600	COG0538	isocitrate dehydrogenase activity
H7F26_21605	COG0372	Belongs to the citrate synthase family
H7F26_21610	COG2707	UPF0756 membrane protein
H7F26_21615	COG0628	permease
H7F26_21620	COG3030	protein affecting phage T7 exclusion by the F plasmid
H7F26_21630	COG0205	6-phosphofructokinase activity
H7F26_21635	COG0825	malonyl-CoA metabolic process
H7F26_21640	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H7F26_21645	COG0281	malic enzyme
H7F26_21650	COG0587	DNA-directed DNA polymerase activity
H7F26_21670	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H7F26_21680	COG4109	DRTGG domain
H7F26_21685	COG1695	Transcriptional regulator
H7F26_21690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F26_21695	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_21705	COG0165	Argininosuccinate lyase
H7F26_21710	COG0137	argininosuccinate synthase activity
H7F26_21715	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7F26_21720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7F26_21725	COG0827	DNA restriction-modification system
H7F26_21730	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H7F26_21735	COG3874	Sporulation protein YtfJ
H7F26_21745	COG1714	RDD family
H7F26_21750	COG0616	signal peptide processing
