locus-tag	class	description
FIU87_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIU87_00010	COG0592	DNA-directed DNA polymerase activity
FIU87_00015	COG2501	S4 domain
FIU87_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIU87_00030	COG0187	DNA topoisomerase II activity
FIU87_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIU87_00040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIU87_00075	COG0517	IMP dehydrogenase activity
FIU87_00075	COG0516	GMP reductase activity
FIU87_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FIU87_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIU87_00105	COG1428	Deoxynucleoside kinase
FIU87_00110	COG1428	Deoxynucleoside kinase
FIU87_00115	COG3858	chitin binding
FIU87_00115	COG1388	LysM domain
FIU87_00120	COG1335	isochorismatase
FIU87_00125	COG0590	tRNA wobble adenosine to inosine editing
FIU87_00145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FIU87_00150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FIU87_00155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIU87_00200	COG1982	Orn Lys Arg decarboxylase major
FIU87_00205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU87_00210	COG3870	Protein conserved in bacteria
FIU87_00215	COG1728	Protein conserved in bacteria
FIU87_00220	COG0470	DNA polymerase III
FIU87_00225	COG1774	PSP1 C-terminal conserved region
FIU87_00230	COG4467	Involved in initiation control of chromosome replication
FIU87_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FIU87_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FIU87_00245	COG2002	toxin-antitoxin pair type II binding
FIU87_00255	COG0084	hydrolase, TatD family'
FIU87_00260	COG3583	domain protein
FIU87_00260	COG3584	3D domain protein
FIU87_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FIU87_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIU87_00280	COG4466	Protein conserved in bacteria
FIU87_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIU87_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIU87_00300	COG0251	oxidation-reduction process
FIU87_00320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIU87_00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIU87_00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FIU87_00335	COG0193	aminoacyl-tRNA hydrolase activity
FIU87_00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIU87_00350	COG2002	toxin-antitoxin pair type II binding
FIU87_00355	COG2244	polysaccharide biosynthetic process
FIU87_00360	COG3956	TIGRFAM MazG family protein
FIU87_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FIU87_00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FIU87_00385	COG1098	S1 RNA binding domain
FIU87_00400	COG2208	phosphoserine phosphatase activity
FIU87_00410	COG2304	oxidoreductase activity
FIU87_00415	COG0515	serine threonine protein kinase
FIU87_00430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU87_00435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FIU87_00440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FIU87_00445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU87_00450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIU87_00455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU87_00460	COG0512	Glutamine amidotransferase of anthranilate synthase
FIU87_00465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU87_00470	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIU87_00475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU87_00480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU87_00485	COG1396	sequence-specific DNA binding
FIU87_00490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU87_00495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIU87_00585	COG3880	PFAM UvrB UvrC protein
FIU87_00590	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FIU87_00595	COG0542	response to heat
FIU87_00600	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FIU87_00610	COG4956	integral membrane protein (PIN domain superfamily)
FIU87_00615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIU87_00620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FIU87_00625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU87_00630	COG1045	serine acetyltransferase
FIU87_00635	COG0215	cysteine-tRNA ligase activity
FIU87_00645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU87_00650	COG3688	RNA-binding protein containing a PIN domain
FIU87_00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIU87_00665	COG0250	Participates in transcription elongation, termination and antitermination
FIU87_00675	COG0081	regulation of translation
FIU87_00680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIU87_00690	COG2813	Specifically methylates the guanine in position
FIU87_00695	COG0085	RNA polymerase activity
FIU87_00700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FIU87_00705	COG1358	cellular component organization or biogenesis
FIU87_00710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FIU87_00715	COG0049	tRNA binding
FIU87_00720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIU87_00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU87_00740	COG0051	transcription antitermination factor activity, RNA binding
FIU87_00745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIU87_00750	COG0088	Forms part of the polypeptide exit tunnel
FIU87_00755	COG0089	rRNA binding
FIU87_00760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FIU87_00765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIU87_00770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIU87_00775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIU87_00780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIU87_00785	COG0255	Belongs to the universal ribosomal protein uL29 family
FIU87_00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIU87_00795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FIU87_00800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIU87_00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIU87_00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIU87_00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FIU87_00830	COG1841	ribosomal large subunit assembly
FIU87_00835	COG0200	Binds to the 23S rRNA
FIU87_00840	COG0201	protein transport
FIU87_00845	COG0563	adenylate kinase activity
FIU87_00850	COG0024	Methionine aminopeptidase
FIU87_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIU87_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FIU87_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIU87_00880	COG0203	ribosomal protein L17
FIU87_00885	COG1122	ATPase activity
FIU87_00890	COG1122	ATPase activity
FIU87_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FIU87_00900	COG0101	tRNA pseudouridine synthase activity
FIU87_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FIU87_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FIU87_00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU87_00935	COG0489	protein tyrosine kinase activity
FIU87_00945	COG2194	sulfuric ester hydrolase activity
FIU87_00950	COG0726	polysaccharide deacetylase
FIU87_01035	COG1595	DNA-templated transcription, initiation
FIU87_01040	COG5662	AntiSigma factor
FIU87_01045	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FIU87_01050	COG4856	YbbR-like protein
FIU87_01055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU87_01075	COG1469	GTP cyclohydrolase I activity
FIU87_01080	COG0717	Belongs to the dCTP deaminase family
FIU87_01085	COG0523	cobalamin synthesis protein
FIU87_01090	COG0523	cobalamin synthesis protein
FIU87_01100	COG0601	transmembrane transport
FIU87_01105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU87_01110	COG0444	Belongs to the ABC transporter superfamily
FIU87_01115	COG1124	(ABC) transporter
FIU87_01135	COG1785	Belongs to the alkaline phosphatase family
FIU87_01140	COG4585	Histidine kinase
FIU87_01145	COG2197	response regulator
FIU87_01165	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIU87_01260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU87_01270	COG5577	PFAM Coat F domain
FIU87_01280	COG0393	Putative heavy-metal-binding
FIU87_01285	COG0789	Transcriptional regulator
FIU87_01290	COG1253	flavin adenine dinucleotide binding
FIU87_01295	COG4536	flavin adenine dinucleotide binding
FIU87_01300	COG0772	Belongs to the SEDS family
FIU87_01305	COG1595	DNA-templated transcription, initiation
FIU87_01340	COG1695	Transcriptional regulator
FIU87_01355	COG4585	Histidine kinase
FIU87_01370	COG1131	(ABC) transporter
FIU87_01385	COG1476	TRANSCRIPTIONal
FIU87_01395	COG0840	transmembrane signaling receptor activity
FIU87_01400	COG1595	DNA-templated transcription, initiation
FIU87_01410	COG1410	methionine synthase
FIU87_01410	COG0646	methionine synthase
FIU87_01415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU87_01415	COG0646	methionine synthase
FIU87_01420	COG0626	cystathionine gamma-synthase activity
FIU87_01425	COG0626	cystathionine gamma-synthase activity
FIU87_01460	COG4988	ABC transporter
FIU87_01465	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FIU87_01470	COG1132	(ABC) transporter
FIU87_01490	COG1227	inorganic diphosphatase activity
FIU87_01505	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_01530	COG3973	AAA domain
FIU87_01540	COG1937	Protein conserved in bacteria
FIU87_01545	COG2608	mercury ion transmembrane transporter activity
FIU87_01550	COG2217	Heavy metal translocating P-type atpase
FIU87_01560	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU87_01580	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU87_01585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FIU87_01590	COG0513	Belongs to the DEAD box helicase family
FIU87_01595	COG3402	PFAM membrane-flanked domain
FIU87_01600	COG3428	Bacterial PH domain
FIU87_01605	COG0705	Rhomboid family
FIU87_01610	COG0736	holo-[acyl-carrier-protein] synthase activity
FIU87_01615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FIU87_01625	COG0864	Transcriptional regulator
FIU87_01630	COG2337	Toxic component of a toxin-antitoxin (TA) module
FIU87_01635	COG1366	Belongs to the anti-sigma-factor antagonist family
FIU87_01640	COG1366	Belongs to the anti-sigma-factor antagonist family
FIU87_01645	COG2172	sigma factor antagonist activity
FIU87_01650	COG2208	phosphoserine phosphatase activity
FIU87_01655	COG1366	Belongs to the anti-sigma-factor antagonist family
FIU87_01660	COG2172	sigma factor antagonist activity
FIU87_01665	COG1191	sigma factor activity
FIU87_01670	COG2208	phosphoserine phosphatase activity
FIU87_01675	COG2183	response to ionizing radiation
FIU87_01680	COG3091	SprT-like family
FIU87_01775	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FIU87_01780	COG0802	atpase or kinase
FIU87_01785	COG1214	PFAM Peptidase M22, glycoprotease
FIU87_01790	COG0456	acetyltransferase
FIU87_01795	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIU87_01805	COG1131	(ABC) transporter
FIU87_01820	COG0488	(ABC) transporter
FIU87_01825	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FIU87_01830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU87_01835	COG0805	protein transport
FIU87_01845	COG1266	CAAX protease self-immunity
FIU87_01850	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIU87_01855	COG0459	protein refolding
FIU87_01880	COG0598	Magnesium transport protein CorA
FIU87_01885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU87_01890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU87_01895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU87_01940	COG1595	DNA-templated transcription, initiation
FIU87_01990	COG0346	lactoylglutathione lyase activity
FIU87_02000	COG1278	Cold shock
FIU87_02005	COG1121	(ABC) transporter
FIU87_02010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU87_02015	COG0803	Belongs to the bacterial solute-binding protein 9 family
FIU87_02025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FIU87_02040	COG0714	Associated with various cellular activities
FIU87_02045	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FIU87_02050	COG1305	Transglutaminase-like
FIU87_02055	COG0519	Catalyzes the synthesis of GMP from XMP
FIU87_02055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIU87_02060	COG2252	PERMEase
FIU87_02100	COG1595	DNA-templated transcription, initiation
FIU87_02110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU87_02115	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FIU87_02125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIU87_02130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FIU87_02135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIU87_02140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FIU87_02145	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU87_02150	COG0047	phosphoribosylformylglycinamidine synthase activity
FIU87_02155	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU87_02160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIU87_02165	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIU87_02170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIU87_02175	COG0138	bifunctional purine biosynthesis protein purh
FIU87_02180	COG0151	Belongs to the GarS family
FIU87_02190	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FIU87_02195	COG1470	cell adhesion involved in biofilm formation
FIU87_02200	COG4496	protein, YerC YecD
FIU87_02210	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FIU87_02215	COG0210	DNA helicase
FIU87_02225	COG4851	CamS sex pheromone cAM373 precursor
FIU87_02245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU87_02250	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU87_02255	COG0154	amidase activity
FIU87_02270	COG1876	peptidase activity
FIU87_02275	COG1585	Membrane protein implicated in regulation of membrane protease activity
FIU87_02280	COG2268	Band 7 protein
FIU87_02285	COG1597	lipid kinase activity
FIU87_02310	COG0175	sulfate reduction
FIU87_02315	COG0306	phosphate transporter
FIU87_02325	COG0529	Catalyzes the synthesis of activated sulfate
FIU87_02330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU87_02340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU87_02365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIU87_02370	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIU87_02385	COG3773	Cell wall hydrolase
FIU87_02440	COG1595	DNA-templated transcription, initiation
FIU87_02450	COG0697	spore germination
FIU87_02475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FIU87_02485	COG3739	integral membrane protein
FIU87_02490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIU87_02495	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FIU87_02515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU87_02535	COG1349	DNA-binding transcription factor activity
FIU87_02560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU87_02575	COG2233	PERMEase
FIU87_02595	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_02660	COG1131	(ABC) transporter
FIU87_02670	COG0640	Transcriptional regulator
FIU87_02690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIU87_02690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIU87_02695	COG2816	NAD+ diphosphatase activity
FIU87_02700	COG4555	ABC transporter
FIU87_02805	COG2190	(PTS) system
FIU87_02805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU87_02805	COG1263	PTS System
FIU87_02810	COG1994	Peptidase M50
FIU87_02815	COG3540	Alkaline phosphatase
FIU87_02820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU87_02825	COG0805	protein transport
FIU87_02840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU87_02860	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FIU87_02910	COG1619	proteins homologs of microcin C7 resistance protein MccF
FIU87_02920	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIU87_02930	COG3655	Transcriptional regulator
FIU87_02950	COG0406	alpha-ribazole phosphatase activity
FIU87_02980	COG2814	Major facilitator Superfamily
FIU87_02985	COG1733	regulation of RNA biosynthetic process
FIU87_03000	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIU87_03040	COG5609	conserved protein (DUF2294)
FIU87_03050	COG0288	reversible hydration of carbon dioxide
FIU87_03065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU87_03075	COG2814	Major facilitator Superfamily
FIU87_03090	COG0840	transmembrane signaling receptor activity
FIU87_03095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU87_03110	COG0640	Transcriptional regulator
FIU87_03115	COG0300	oxidoreductase activity
FIU87_03135	COG0697	spore germination
FIU87_03180	COG2226	methyltransferase
FIU87_03200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU87_03245	COG2226	methyltransferase
FIU87_03275	COG0456	acetyltransferase
FIU87_03275	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FIU87_03340	COG0084	hydrolase, TatD family'
FIU87_03350	COG0328	RNA-DNA hybrid ribonuclease activity
FIU87_03350	COG3341	Caulimovirus viroplasmin
FIU87_03420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FIU87_03425	COG2356	endonuclease I
FIU87_03435	COG0156	8-amino-7-oxononanoate synthase activity
FIU87_03455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIU87_03495	COG0251	oxidation-reduction process
FIU87_03500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU87_03510	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FIU87_03515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU87_03575	COG1940	carbohydrate kinase activity
FIU87_03575	COG1846	Transcriptional regulator
FIU87_03585	COG0395	ABC-type sugar transport system, permease component
FIU87_03595	COG1501	Belongs to the glycosyl hydrolase 31 family
FIU87_03615	COG1408	metallophosphoesterase
FIU87_03625	COG0640	Transcriptional regulator
FIU87_03645	COG1129	ABC transporter
FIU87_03670	COG1131	(ABC) transporter
FIU87_03675	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FIU87_03685	COG4682	membrane
FIU87_03705	COG1122	ATPase activity
FIU87_03715	COG0408	coproporphyrinogen oxidase activity
FIU87_03780	COG2304	oxidoreductase activity
FIU87_03815	COG1607	acyl-coa hydrolase
FIU87_03825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FIU87_03830	COG1132	(ABC) transporter
FIU87_03850	COG1309	transcriptional regulator
FIU87_03855	COG2814	Major facilitator Superfamily
FIU87_03875	COG0322	excinuclease ABC activity
FIU87_03895	COG3290	protein histidine kinase activity
FIU87_03900	COG3279	Response regulator of the LytR AlgR family
FIU87_03905	COG4555	ABC transporter
FIU87_03910	COG1668	transmembrane transport
FIU87_03930	COG2186	Transcriptional regulator
FIU87_03940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU87_03945	COG0567	Dehydrogenase, E1 component
FIU87_03950	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU87_03970	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIU87_03975	COG1183	phosphatidylcholine synthase activity
FIU87_03980	COG1960	acyl-CoA dehydrogenase activity
FIU87_03985	COG1966	Carbon starvation protein
FIU87_03990	COG0166	Belongs to the GPI family
FIU87_03995	COG1012	belongs to the aldehyde dehydrogenase family
FIU87_04000	COG2814	Major facilitator Superfamily
FIU87_04005	COG4191	Histidine kinase
FIU87_04015	COG2368	4-hydroxyphenylacetate
FIU87_04030	COG0154	amidase activity
FIU87_04035	COG1132	(ABC) transporter
FIU87_04040	COG1132	(ABC) transporter
FIU87_04045	COG1115	amino acid carrier protein
FIU87_04060	COG0723	plastoquinol--plastocyanin reductase activity
FIU87_04060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU87_04065	COG0513	Belongs to the DEAD box helicase family
FIU87_04070	COG2124	cytochrome p450
FIU87_04080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU87_04100	COG2244	polysaccharide biosynthetic process
FIU87_04105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FIU87_04110	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FIU87_04125	COG1077	Cell shape determining protein MreB Mrl
FIU87_04170	COG0745	RESPONSE REGULATOR receiver
FIU87_04175	COG5002	protein histidine kinase activity
FIU87_04180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU87_04195	COG1988	membrane-bound metal-dependent
FIU87_04205	COG4840	Belongs to the UPF0435 family
FIU87_04215	COG1295	ribonuclease BN
FIU87_04225	COG2217	Heavy metal translocating P-type atpase
FIU87_04250	COG0477	Major facilitator Superfamily
FIU87_04260	COG0024	Methionine aminopeptidase
FIU87_04280	COG0662	Cupin 2, conserved barrel domain protein
FIU87_04285	COG0247	lactate metabolic process
FIU87_04290	COG0277	FAD linked oxidase domain protein
FIU87_04295	COG3871	stress protein (general stress protein 26)
FIU87_04300	COG2364	Membrane
FIU87_04320	COG0535	radical SAM domain protein
FIU87_04340	COG4134	Bacterial extracellular solute-binding protein
FIU87_04350	COG4149	molybdate abc transporter
FIU87_04355	COG3842	ATPase activity
FIU87_04365	COG0398	Pfam SNARE associated Golgi protein
FIU87_04370	COG1213	nucleotidyl transferase
FIU87_04370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU87_04410	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FIU87_04415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIU87_04430	COG1696	Membrane protein involved in D-alanine export
FIU87_04455	COG5337	Spore coat protein CotH
FIU87_04460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU87_04465	COG0438	transferase activity, transferring glycosyl groups
FIU87_04470	COG0438	transferase activity, transferring glycosyl groups
FIU87_04475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIU87_04485	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FIU87_04505	COG3973	AAA domain
FIU87_04540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIU87_04545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIU87_04550	COG0592	DNA-directed DNA polymerase activity
FIU87_04580	COG3237	CsbD-like
FIU87_04585	COG4213	ABC transporter substrate-binding protein
FIU87_04595	COG4214	carbohydrate transport
FIU87_04605	COG2972	Histidine kinase
FIU87_04610	COG2207	Transcriptional regulator
FIU87_04610	COG4753	response regulator
FIU87_04615	COG4213	ABC transporter substrate-binding protein
FIU87_04625	COG0673	inositol 2-dehydrogenase activity
FIU87_04630	COG1131	(ABC) transporter
FIU87_04665	COG0697	spore germination
FIU87_04670	COG3239	Fatty acid desaturase
FIU87_04680	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIU87_04680	COG2199	diguanylate cyclase activity
FIU87_04690	COG1305	Transglutaminase-like
FIU87_04700	COG1476	TRANSCRIPTIONal
FIU87_04710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU87_04740	COG1657	PFAM Prenyltransferase squalene oxidase
FIU87_04760	COG2271	Major facilitator Superfamily
FIU87_04780	COG0861	Integral membrane protein TerC family
FIU87_04785	COG1595	DNA-templated transcription, initiation
FIU87_04820	COG1051	belongs to the nudix hydrolase family
FIU87_04910	COG1388	LysM domain
FIU87_04915	COG0745	RESPONSE REGULATOR receiver
FIU87_04920	COG5002	protein histidine kinase activity
FIU87_04965	COG0456	acetyltransferase
FIU87_04970	COG1595	DNA-templated transcription, initiation
FIU87_04985	COG1464	Belongs to the NlpA lipoprotein family
FIU87_04990	COG2011	ABC-type metal ion transport system permease component
FIU87_04995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FIU87_05015	COG1595	DNA-templated transcription, initiation
FIU87_05020	COG3711	transcriptional antiterminator
FIU87_05025	COG1263	PTS System
FIU87_05025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU87_05025	COG2190	(PTS) system
FIU87_05030	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FIU87_05040	COG0716	FMN binding
FIU87_05050	COG0716	FMN binding
FIU87_05065	COG3069	C4-dicarboxylate transmembrane transporter activity
FIU87_05085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIU87_05135	COG1090	epimerase
FIU87_05140	COG2137	regulation of response to DNA damage stimulus
FIU87_05145	COG0300	oxidoreductase activity
FIU87_05170	COG1988	membrane-bound metal-dependent
FIU87_05180	COG1194	a g-specific adenine glycosylase
FIU87_05190	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_05205	COG3557	Belongs to the UPF0374 family
FIU87_05210	COG1132	(ABC) transporter
FIU87_05215	COG4129	membrane
FIU87_05220	COG0069	glutamate synthase activity
FIU87_05220	COG0070	glutamate synthase
FIU87_05220	COG0067	glutamate synthase
FIU87_05235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIU87_05240	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIU87_05245	COG2096	Adenosyltransferase
FIU87_05250	COG0735	belongs to the Fur family
FIU87_05360	COG4974	Belongs to the 'phage' integrase family
FIU87_05415	COG2337	Toxic component of a toxin-antitoxin (TA) module
FIU87_05425	COG0582	viral genome integration into host DNA
FIU87_05450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FIU87_05555	COG3382	B3 4 domain protein
FIU87_05575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FIU87_05585	COG2766	serine protein kinase
FIU87_05600	COG2205	protein histidine kinase activity
FIU87_05605	COG0747	negative chemotaxis
FIU87_05615	COG0601	transmembrane transport
FIU87_05620	COG0444	Belongs to the ABC transporter superfamily
FIU87_05625	COG4608	Belongs to the ABC transporter superfamily
FIU87_05645	COG2514	catechol 2,3-dioxygenase activity
FIU87_05655	COG0456	acetyltransferase
FIU87_05665	COG0346	lactoylglutathione lyase activity
FIU87_05670	COG1253	flavin adenine dinucleotide binding
FIU87_05675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIU87_05680	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU87_05680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU87_05690	COG2205	protein histidine kinase activity
FIU87_05700	COG0789	Transcriptional regulator
FIU87_05715	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIU87_05725	COG0656	L-ascorbic acid biosynthetic process
FIU87_05735	COG0456	acetyltransferase
FIU87_05740	COG0564	pseudouridine synthase activity
FIU87_05755	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FIU87_05760	COG3153	acetyltransferase
FIU87_05760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU87_05765	COG0726	polysaccharide deacetylase
FIU87_05770	COG4989	oxidoreductase activity
FIU87_05780	COG1595	DNA-templated transcription, initiation
FIU87_05795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU87_05805	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU87_05810	COG1501	Belongs to the glycosyl hydrolase 31 family
FIU87_05825	COG1012	belongs to the aldehyde dehydrogenase family
FIU87_05835	COG2188	Transcriptional regulator
FIU87_05840	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FIU87_05845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIU87_05850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FIU87_05855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU87_05860	COG0300	oxidoreductase activity
FIU87_05865	COG2203	Gaf domain
FIU87_05865	COG4585	Histidine kinase
FIU87_05870	COG2197	response regulator
FIU87_05875	COG0431	NADPH-dependent FMN reductase
FIU87_05890	COG2239	Acts as a magnesium transporter
FIU87_05895	COG0730	response to heat
FIU87_05900	COG2719	SpoVR family
FIU87_05935	COG1695	Transcriptional regulator
FIU87_05950	COG2112	serine threonine protein kinase
FIU87_05955	COG1595	DNA-templated transcription, initiation
FIU87_05970	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIU87_05975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU87_05980	COG0569	domain protein
FIU87_05985	COG0745	RESPONSE REGULATOR receiver
FIU87_05990	COG5002	protein histidine kinase activity
FIU87_05990	COG3850	Histidine kinase
FIU87_05995	COG0398	Pfam SNARE associated Golgi protein
FIU87_06000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU87_06025	COG0582	viral genome integration into host DNA
FIU87_06040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIU87_06065	COG0586	Pfam SNARE associated Golgi protein
FIU87_06075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU87_06080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU87_06085	COG1366	Belongs to the anti-sigma-factor antagonist family
FIU87_06095	COG1301	dicarboxylic acid transport
FIU87_06100	COG2076	Multidrug Resistance protein
FIU87_06105	COG2076	Multidrug Resistance protein
FIU87_06125	COG0589	response to stress
FIU87_06130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU87_06135	COG2814	Major facilitator Superfamily
FIU87_06140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FIU87_06145	COG4721	ABC-type cobalt transport system, permease component
FIU87_06150	COG1122	ATPase activity
FIU87_06160	COG0352	thiamine-phosphate diphosphorylase activity
FIU87_06165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU87_06170	COG2104	thiamine diphosphate biosynthetic process
FIU87_06175	COG2022	thiamine diphosphate biosynthetic process
FIU87_06180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU87_06185	COG0351	phosphomethylpyrimidine kinase
FIU87_06205	COG1132	(ABC) transporter
FIU87_06210	COG1132	(ABC) transporter
FIU87_06220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU87_06225	COG0765	amino acid transport
FIU87_06230	COG1126	abc transporter atp-binding protein
FIU87_06245	COG3842	ATPase activity
FIU87_06250	COG2508	Transcriptional regulator
FIU87_06270	COG0189	ligase activity
FIU87_06290	COG3679	Belongs to the UPF0342 family
FIU87_06295	COG0561	phosphatase activity
FIU87_06305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU87_06315	COG1024	Enoyl-CoA hydratase
FIU87_06325	COG4152	abc transporter atp-binding protein
FIU87_06330	COG1668	transmembrane transport
FIU87_06335	COG0420	3'-5' exonuclease activity
FIU87_06340	COG4717	serine-type aminopeptidase activity
FIU87_06345	COG2814	Major facilitator Superfamily
FIU87_06350	COG3481	metal-dependent phosphohydrolase, HD sub domain
FIU87_06360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU87_06380	COG1846	Transcriptional regulator
FIU87_06400	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FIU87_06410	COG0537	adenosine 5'-monophosphoramidase activity
FIU87_06415	COG1131	(ABC) transporter
FIU87_06420	COG4473	ABC transporter
FIU87_06430	COG1473	amidohydrolase
FIU87_06445	COG4585	Histidine kinase
FIU87_06450	COG2197	response regulator
FIU87_06455	COG2329	Antibiotic biosynthesis monooxygenase
FIU87_06460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU87_06465	COG4191	Histidine kinase
FIU87_06470	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIU87_06485	COG1309	transcriptional regulator
FIU87_06490	COG1511	domain protein
FIU87_06495	COG1609	Transcriptional regulator
FIU87_06500	COG1234	tRNA 3'-trailer cleavage
FIU87_06505	COG0095	Lipoate-protein ligase
FIU87_06510	COG0318	PFAM AMP-dependent synthetase and ligase
FIU87_06515	COG1024	Enoyl-CoA hydratase
FIU87_06530	COG0501	Belongs to the peptidase M48B family
FIU87_06535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIU87_06540	COG2224	Isocitrate lyase
FIU87_06550	COG4903	ComK protein
FIU87_06555	COG2323	membrane
FIU87_06565	COG4946	Tricorn protease homolog
FIU87_06565	COG0823	Involved in the tonB-independent uptake of proteins
FIU87_06565	COG1506	peptidase
FIU87_06580	COG0398	Pfam SNARE associated Golgi protein
FIU87_06590	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_06600	COG2814	Major facilitator Superfamily
FIU87_06605	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FIU87_06610	COG1074	ATP-dependent DNA helicase activity
FIU87_06615	COG0420	3'-5' exonuclease activity
FIU87_06620	COG0419	ATPase involved in DNA repair
FIU87_06655	COG2311	Membrane
FIU87_06665	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU87_06670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIU87_06685	COG0367	asparagine synthase
FIU87_06700	COG1562	ergosterol biosynthetic process
FIU87_06705	COG1233	COG1233 Phytoene dehydrogenase and related
FIU87_06710	COG1216	Glycosyl transferase, family 2
FIU87_06725	COG0004	ammonium transporteR
FIU87_06730	COG0347	Belongs to the P(II) protein family
FIU87_06735	COG0534	Mate efflux family protein
FIU87_06740	COG1917	Cupin 2, conserved barrel domain protein
FIU87_06740	COG2207	Transcriptional regulator
FIU87_06750	COG2182	Extracellular solute-binding protein
FIU87_06755	COG1175	transmembrane transport
FIU87_06760	COG3833	ABC-type maltose transport systems, permease component
FIU87_06765	COG0366	Alpha amylase catalytic
FIU87_06765	COG1874	Beta-galactosidase
FIU87_06785	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_06790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU87_06795	COG1666	GTP binding
FIU87_06800	COG2996	Protein conserved in bacteria
FIU87_06810	COG1307	EDD domain protein, DegV family
FIU87_06815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FIU87_06830	COG0561	phosphatase activity
FIU87_06835	COG1073	alpha beta
FIU87_06840	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU87_06855	COG0542	response to heat
FIU87_06865	COG2267	carboxylic ester hydrolase activity
FIU87_06875	COG1744	ABC transporter substrate-binding protein PnrA-like
FIU87_06885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU87_06890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU87_06895	COG5504	Zn-dependent protease
FIU87_06900	COG0444	Belongs to the ABC transporter superfamily
FIU87_06905	COG4608	Belongs to the ABC transporter superfamily
FIU87_06915	COG0601	transmembrane transport
FIU87_06920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU87_06930	COG0180	Tryptophanyl-tRNA synthetase
FIU87_06940	COG4166	transmembrane transport
FIU87_06945	COG0601	transmembrane transport
FIU87_06950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU87_06955	COG0444	Belongs to the ABC transporter superfamily
FIU87_06960	COG4608	Belongs to the ABC transporter superfamily
FIU87_06975	COG0456	acetyltransferase
FIU87_06990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU87_06995	COG1393	Belongs to the ArsC family
FIU87_07000	COG0861	Integral membrane protein TerC family
FIU87_07005	COG4862	establishment of competence for transformation
FIU87_07010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU87_07020	COG1164	Oligoendopeptidase f
FIU87_07045	COG2346	COG2346, Truncated hemoglobins
FIU87_07050	COG0741	lytic transglycosylase activity
FIU87_07055	COG4116	CYTH
FIU87_07065	COG2357	RelA SpoT domain protein
FIU87_07070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIU87_07075	COG0564	pseudouridine synthase activity
FIU87_07080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIU87_07085	COG0589	response to stress
FIU87_07085	COG0475	glutathione-regulated potassium exporter activity
FIU87_07090	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU87_07105	COG0438	transferase activity, transferring glycosyl groups
FIU87_07115	COG0438	transferase activity, transferring glycosyl groups
FIU87_07120	COG1215	transferase activity, transferring glycosyl groups
FIU87_07155	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FIU87_07170	COG1091	dTDP-4-dehydrorhamnose reductase activity
FIU87_07240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU87_07255	COG2323	membrane
FIU87_07280	COG0210	DNA helicase
FIU87_07290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU87_07295	COG2323	membrane
FIU87_07300	COG2153	protein acetylation
FIU87_07305	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FIU87_07310	COG2382	esterase
FIU87_07330	COG1999	signal sequence binding
FIU87_07335	COG1418	mRNA catabolic process
FIU87_07395	COG1363	Peptidase, m42
FIU87_07410	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FIU87_07430	COG2894	cell division
FIU87_07450	COG1533	DNA photolyase activity
FIU87_07460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU87_07470	COG1388	LysM domain
FIU87_07470	COG3584	3D domain protein
FIU87_07475	COG0671	phosphoesterase, PA-phosphatase related
FIU87_07495	COG3844	kynureninase activity
FIU87_07500	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FIU87_07520	COG0697	spore germination
FIU87_07525	COG0668	transmembrane transport
FIU87_07545	COG1793	dna ligase
FIU87_07545	COG3285	dna ligase
FIU87_07550	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FIU87_07560	COG1191	sigma factor activity
FIU87_07575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU87_07580	COG2814	Major facilitator Superfamily
FIU87_07610	COG5002	protein histidine kinase activity
FIU87_07615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIU87_07625	COG0640	Transcriptional regulator
FIU87_07630	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FIU87_07635	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FIU87_07640	COG1278	Cold shock
FIU87_07645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU87_07650	COG0436	Aminotransferase
FIU87_07655	COG1850	ribulose-bisphosphate carboxylase activity
FIU87_07660	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FIU87_07665	COG0235	Class ii aldolase
FIU87_07670	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FIU87_07685	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU87_07695	COG2861	carbohydrate metabolic process
FIU87_07710	COG1846	Transcriptional regulator
FIU87_07735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU87_07740	COG3949	Membrane
FIU87_07770	COG4325	translation initiation factor activity
FIU87_07780	COG0720	synthase
FIU87_07790	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIU87_07805	COG4873	Protein conserved in bacteria
FIU87_07860	COG1725	Transcriptional regulator
FIU87_07865	COG1131	(ABC) transporter
FIU87_07895	COG0596	Alpha beta hydrolase
FIU87_07910	COG3546	catalase activity
FIU87_07930	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_07945	COG2986	histidine ammonia-lyase
FIU87_07960	COG0010	Belongs to the arginase family
FIU87_07965	COG2084	Dehydrogenase
FIU87_07970	COG4191	Histidine kinase
FIU87_07975	COG0733	neurotransmitter:sodium symporter activity
FIU87_07980	COG1404	Belongs to the peptidase S8 family
FIU87_07990	COG0436	Aminotransferase
FIU87_08005	COG2205	protein histidine kinase activity
FIU87_08015	COG2270	Major facilitator Superfamily
FIU87_08020	COG0071	Belongs to the small heat shock protein (HSP20) family
FIU87_08050	COG1473	amidohydrolase
FIU87_08065	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIU87_08070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU87_08075	COG3594	Acyltransferase
FIU87_08090	COG0791	NLP P60 protein
FIU87_08090	COG1388	LysM domain
FIU87_08105	COG0596	Alpha beta hydrolase
FIU87_08110	COG5522	Integral membrane protein (intg_mem_TP0381)
FIU87_08125	COG1366	Belongs to the anti-sigma-factor antagonist family
FIU87_08140	COG1960	acyl-CoA dehydrogenase activity
FIU87_08145	COG0183	Belongs to the thiolase family
FIU87_08150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU87_08155	COG0318	PFAM AMP-dependent synthetase and ligase
FIU87_08165	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU87_08175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU87_08180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU87_08185	COG0129	dihydroxy-acid dehydratase activity
FIU87_08190	COG0028	Belongs to the TPP enzyme family
FIU87_08195	COG0440	acetolactate synthase activity
FIU87_08200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIU87_08205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU87_08215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIU87_08220	COG0066	3-isopropylmalate dehydratase activity
FIU87_08235	COG4589	Belongs to the CDS family
FIU87_08250	COG0745	RESPONSE REGULATOR receiver
FIU87_08255	COG5002	protein histidine kinase activity
FIU87_08270	COG0702	epimerase
FIU87_08275	COG3610	response to peptide
FIU87_08280	COG2966	Psort location CytoplasmicMembrane, score
FIU87_08285	COG2340	Cysteine-rich secretory protein family
FIU87_08295	COG3226	Transcriptional regulator
FIU87_08305	COG0363	glucosamine-6-phosphate deaminase activity
FIU87_08310	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIU87_08315	COG1247	-acetyltransferase
FIU87_08325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU87_08345	COG1686	Belongs to the peptidase S11 family
FIU87_08355	COG1960	acyl-CoA dehydrogenase activity
FIU87_08365	COG4145	pantothenate transmembrane transporter activity
FIU87_08375	COG0658	competence protein
FIU87_08375	COG2333	competence protein COMEC
FIU87_08390	COG2190	(PTS) system
FIU87_08395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU87_08395	COG1263	PTS System
FIU87_08400	COG0366	Alpha amylase catalytic
FIU87_08405	COG0366	Alpha amylase catalytic
FIU87_08410	COG2188	Transcriptional regulator
FIU87_08415	COG1164	Oligoendopeptidase f
FIU87_08420	COG0784	Response regulator, receiver
FIU87_08420	COG0835	chemotaxis
FIU87_08430	COG3437	response regulator, receiver
FIU87_08430	COG2770	Histidine kinase
FIU87_08435	COG1376	ErfK ybiS ycfS ynhG family protein
FIU87_08445	COG1408	metallophosphoesterase
FIU87_08450	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_08455	COG0791	NLP P60 protein
FIU87_08455	COG1388	LysM domain
FIU87_08460	COG2200	EAL domain
FIU87_08480	COG4703	Protein of unknown function (DUF1797)
FIU87_08485	COG5506	Protein of unknown function (DUF1694)
FIU87_08490	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FIU87_08505	COG0517	IMP dehydrogenase activity
FIU87_08510	COG2814	Major facilitator Superfamily
FIU87_08520	COG0583	DNA-binding transcription factor activity
FIU87_08535	COG1473	amidohydrolase
FIU87_08545	COG0668	transmembrane transport
FIU87_08550	COG0450	alkyl hydroperoxide reductase
FIU87_08555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU87_08560	COG1132	(ABC) transporter
FIU87_08565	COG1132	(ABC) transporter
FIU87_08570	COG0569	domain protein
FIU87_08575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FIU87_08585	COG0697	spore germination
FIU87_08590	COG0561	phosphatase activity
FIU87_08595	COG0242	peptide deformylase activity
FIU87_08610	COG0022	dehydrogenase e1 component
FIU87_08615	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU87_08620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU87_08650	COG1982	Orn Lys Arg decarboxylase major
FIU87_08660	COG4476	Belongs to the UPF0223 family
FIU87_08665	COG4493	Belongs to the UPF0637 family
FIU87_08675	COG0483	inositol monophosphate 1-phosphatase activity
FIU87_08705	COG4896	Protein conserved in bacteria
FIU87_08720	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FIU87_08725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIU87_08730	COG2066	Belongs to the glutaminase family
FIU87_08735	COG4838	Belongs to the UPF0358 family
FIU87_08740	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FIU87_08745	COG1612	heme a metabolic process
FIU87_08750	COG0109	protoheme IX farnesyltransferase activity
FIU87_08775	COG3336	cytochrome c oxidase
FIU87_08800	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FIU87_08805	COG2340	Cysteine-rich secretory protein family
FIU87_08835	COG3679	Belongs to the UPF0342 family
FIU87_08845	COG4471	UPF0298 protein
FIU87_08855	COG0742	ribosomal rna small subunit methyltransferase
FIU87_08860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FIU87_08865	COG3314	Sporulation integral membrane protein YlbJ
FIU87_08870	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIU87_08875	COG3480	Lon protease (S16) C-terminal proteolytic domain
FIU87_08880	COG1323	Belongs to the UPF0348 family
FIU87_08885	COG1399	metal-binding, possibly nucleic acid-binding protein
FIU87_08895	COG1024	Enoyl-CoA hydratase
FIU87_08905	COG3011	Protein conserved in bacteria
FIU87_08910	COG0454	-acetyltransferase
FIU87_08915	COG0439	Biotin carboxylase
FIU87_08920	COG0511	ligase activity, forming carbon-carbon bonds
FIU87_08925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU87_08930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FIU87_08940	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FIU87_08945	COG2001	Belongs to the MraZ family
FIU87_08950	COG0275	rRNA processing
FIU87_08965	COG0768	penicillin binding
FIU87_08975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU87_08980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIU87_08985	COG0772	Belongs to the SEDS family
FIU87_08990	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIU87_08995	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIU87_09000	COG3879	Bacterial protein of unknown function (DUF881)
FIU87_09005	COG3879	Bacterial protein of unknown function (DUF881)
FIU87_09010	COG3856	small basic protein
FIU87_09015	COG0849	cell division
FIU87_09020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIU87_09030	COG1191	sigma factor activity
FIU87_09035	COG1191	sigma factor activity
FIU87_09040	COG1873	PFAM PRC-barrel domain
FIU87_09050	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIU87_09055	COG1799	cell septum assembly
FIU87_09060	COG0762	integral membrane protein
FIU87_09065	COG2302	S4 RNA-binding domain
FIU87_09070	COG3599	regulation of cell shape
FIU87_09080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FIU87_09085	COG0564	pseudouridine synthase activity
FIU87_09090	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FIU87_09095	COG2233	PERMEase
FIU87_09100	COG0540	Belongs to the ATCase OTCase family
FIU87_09105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FIU87_09115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIU87_09135	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIU87_09150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FIU87_09155	COG1561	YicC-like family, N-terminal region
FIU87_09160	COG2052	Domain of unknown function (DUF370)
FIU87_09165	COG0194	GDP metabolic process
FIU87_09170	COG1758	RNA polymerase activity
FIU87_09175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FIU87_09180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FIU87_09190	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FIU87_09195	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIU87_09195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU87_09200	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIU87_09205	COG0631	protein serine/threonine phosphatase activity
FIU87_09210	COG2815	serine threonine protein kinase
FIU87_09210	COG0515	serine threonine protein kinase
FIU87_09215	COG1162	GTPase activity
FIU87_09220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FIU87_09225	COG1564	THIamine pyrophosphokinase
FIU87_09230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FIU87_09235	COG1302	Protein conserved in bacteria
FIU87_09240	COG1461	Dihydroxyacetone kinase
FIU87_09245	COG1760	l-serine dehydratase
FIU87_09250	COG1760	l-serine dehydratase
FIU87_09255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIU87_09265	COG0416	fatty acid biosynthetic process
FIU87_09270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FIU87_09275	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_09280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIU87_09285	COG0571	ribonuclease III activity
FIU87_09290	COG1196	nuclear chromosome segregation
FIU87_09295	COG0552	protein localization to endoplasmic reticulum
FIU87_09305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIU87_09315	COG1837	Belongs to the UPF0109 family
FIU87_09320	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIU87_09325	COG0336	Belongs to the RNA methyltransferase TrmD family
FIU87_09330	COG0335	large ribosomal subunit rRNA binding
FIU87_09365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FIU87_09370	COG0758	DNA mediated transformation
FIU87_09375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU87_09380	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FIU87_09385	COG4974	Belongs to the 'phage' integrase family
FIU87_09395	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FIU87_09400	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FIU87_09405	COG1815	bacterial-type flagellum-dependent cell motility
FIU87_09410	COG1558	bacterial-type flagellum-dependent cell motility
FIU87_09415	COG1677	Flagellar hook-basal body complex protein FliE
FIU87_09420	COG1766	The M ring may be actively involved in energy transduction
FIU87_09425	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU87_09435	COG1157	protein secretion by the type III secretion system
FIU87_09440	COG2882	bacterial-type flagellum organization
FIU87_09455	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FIU87_09470	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU87_09475	COG1776	CheC inhibitor of MCP methylation
FIU87_09475	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU87_09480	COG2201	protein-glutamate methylesterase activity
FIU87_09485	COG3190	flagellar
FIU87_09490	COG1338	Plays a role in the flagellum-specific transport system
FIU87_09495	COG1987	bacterial-type flagellum assembly
FIU87_09500	COG1684	flagellar biosynthetic protein fliR
FIU87_09505	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIU87_09510	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIU87_09515	COG1419	protein localization to endoplasmic reticulum
FIU87_09520	COG0455	bacterial-type flagellum organization
FIU87_09525	COG2201	protein-glutamate methylesterase activity
FIU87_09530	COG0643	Histidine kinase
FIU87_09530	COG2198	Histidine kinase
FIU87_09535	COG0835	chemotaxis
FIU87_09540	COG1776	CheC inhibitor of MCP methylation
FIU87_09545	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FIU87_09550	COG1191	sigma factor activity
FIU87_09560	COG0052	Belongs to the universal ribosomal protein uS2 family
FIU87_09585	COG4589	Belongs to the CDS family
FIU87_09595	COG0750	zinc metalloprotease
FIU87_09605	COG2176	DNA-directed DNA polymerase activity
FIU87_09620	COG2176	DNA-directed DNA polymerase activity
FIU87_09625	COG0779	Required for maturation of 30S ribosomal subunits
FIU87_09630	COG0195	Participates in both transcription termination and antitermination
FIU87_09635	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FIU87_09640	COG1358	cellular component organization or biogenesis
FIU87_09650	COG1550	Protein conserved in bacteria
FIU87_09655	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FIU87_09660	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FIU87_09665	COG0196	riboflavin kinase activity
FIU87_09670	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIU87_09675	COG1185	polyribonucleotide nucleotidyltransferase activity
FIU87_09680	COG0726	polysaccharide deacetylase
FIU87_09685	COG0612	Peptidase, M16
FIU87_09690	COG1873	PFAM PRC-barrel domain
FIU87_09695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU87_09700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FIU87_09705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIU87_09710	COG0527	aspartate kinase activity
FIU87_09715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU87_09720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FIU87_09725	COG0740	serine-type endopeptidase activity
FIU87_09735	COG4980	gas vesicle protein
FIU87_09735	COG1674	ftsk spoiiie
FIU87_09740	COG2188	Transcriptional regulator
FIU87_09745	COG0612	Peptidase, M16
FIU87_09750	COG0612	Peptidase, M16
FIU87_09755	COG0300	oxidoreductase activity
FIU87_09770	COG1426	Protein conserved in bacteria
FIU87_09775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU87_09780	COG1546	Belongs to the CinA family
FIU87_09780	COG1058	Belongs to the CinA family
FIU87_09785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIU87_09790	COG1418	mRNA catabolic process
FIU87_09795	COG1692	metallophosphoesterase
FIU87_09800	COG2359	stage V sporulation protein S
FIU87_09810	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FIU87_09810	COG0674	pyruvate-flavodoxin oxidoreductase activity
FIU87_09815	COG1013	pyruvate-flavodoxin oxidoreductase activity
FIU87_09820	COG1063	alcohol dehydrogenase
FIU87_09825	COG0156	8-amino-7-oxononanoate synthase activity
FIU87_09830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU87_09835	COG4550	Control of competence regulator ComK, YlbF/YmcA
FIU87_09845	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FIU87_09850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FIU87_09855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIU87_09865	COG0464	growth
FIU87_09890	COG2860	membrane
FIU87_09895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIU87_09900	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FIU87_09905	COG0789	Transcriptional regulator
FIU87_09910	COG0174	glutamine synthetase
FIU87_09920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU87_09965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU87_09970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIU87_09975	COG4224	UPF0291 protein
FIU87_09990	COG3763	UPF0154 protein
FIU87_09995	COG1132	(ABC) transporter
FIU87_10000	COG1132	(ABC) transporter
FIU87_10010	COG0785	Cytochrome C biogenesis protein
FIU87_10015	COG2201	protein-glutamate methylesterase activity
FIU87_10025	COG4846	Membrane protein involved in cytochrome C biogenesis
FIU87_10035	COG1484	DNA-dependent DNA replication
FIU87_10040	COG0714	Associated with various cellular activities
FIU87_10060	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FIU87_10065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIU87_10100	COG1131	(ABC) transporter
FIU87_10135	COG0709	Synthesizes selenophosphate from selenide and ATP
FIU87_10160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FIU87_10170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU87_10195	COG0824	Thioesterase
FIU87_10205	COG4841	protein insertion into membrane
FIU87_10220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU87_10225	COG4326	sporulation control protein
FIU87_10230	COG0588	phosphoglycerate mutase activity
FIU87_10235	COG0346	lactoylglutathione lyase activity
FIU87_10250	COG1832	CoA-binding protein
FIU87_10255	COG0187	DNA topoisomerase II activity
FIU87_10260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIU87_10265	COG1335	isochorismatase
FIU87_10315	COG2132	Multicopper oxidase
FIU87_10320	COG0697	spore germination
FIU87_10325	COG0531	amino acid
FIU87_10345	COG0604	alcohol dehydrogenase
FIU87_10380	COG1131	(ABC) transporter
FIU87_10405	COG1511	domain protein
FIU87_10420	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIU87_10425	COG1823	symporter activity
FIU87_10460	COG2197	response regulator
FIU87_10465	COG4585	Histidine kinase
FIU87_10480	COG1271	oxidase subunit
FIU87_10485	COG1294	oxidase, subunit
FIU87_10525	COG4565	transcriptional regulatory protein
FIU87_10530	COG3290	protein histidine kinase activity
FIU87_10535	COG2391	methyltransferase activity
FIU87_10570	COG0346	lactoylglutathione lyase activity
FIU87_10595	COG0714	Associated with various cellular activities
FIU87_10615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU87_10620	COG1785	Belongs to the alkaline phosphatase family
FIU87_10625	COG1082	Xylose isomerase domain protein TIM barrel
FIU87_10640	COG0318	PFAM AMP-dependent synthetase and ligase
FIU87_10645	COG4264	IucA IucC family
FIU87_10655	COG2207	Transcriptional regulator
FIU87_10655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU87_10665	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FIU87_10675	COG0003	Pfam Anion-transporting ATPase
FIU87_10685	COG1966	Carbon starvation protein
FIU87_10730	COG2353	YceI-like domain
FIU87_10770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIU87_10785	COG2309	aminopeptidase activity
FIU87_10805	COG0708	Exodeoxyribonuclease III
FIU87_10825	COG0644	oxidoreductase
FIU87_10830	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FIU87_10840	COG1051	belongs to the nudix hydrolase family
FIU87_10845	COG0583	DNA-binding transcription factor activity
FIU87_10850	COG0372	Belongs to the citrate synthase family
FIU87_10855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FIU87_10870	COG1295	ribonuclease BN
FIU87_10875	COG1834	amidinotransferase
FIU87_10880	COG2340	Cysteine-rich secretory protein family
FIU87_10890	COG0693	protein deglycase activity
FIU87_10895	COG0165	Argininosuccinate lyase
FIU87_10900	COG0137	argininosuccinate synthase activity
FIU87_10905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FIU87_10910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIU87_10915	COG0505	Belongs to the CarA family
FIU87_10920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIU87_10925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIU87_10930	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FIU87_10945	COG0673	inositol 2-dehydrogenase activity
FIU87_10955	COG0318	PFAM AMP-dependent synthetase and ligase
FIU87_10960	COG2223	nitrite transmembrane transporter activity
FIU87_10970	COG0346	lactoylglutathione lyase activity
FIU87_10975	COG2404	hydrolase activity, acting on ester bonds
FIU87_10980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU87_10990	COG0514	ATP-dependent DNA helicase (RecQ)
FIU87_10995	COG1012	belongs to the aldehyde dehydrogenase family
FIU87_11010	COG0488	(ABC) transporter
FIU87_11015	COG0628	permease
FIU87_11020	COG1272	protein, Hemolysin III
FIU87_11030	COG2133	pyrroloquinoline quinone binding
FIU87_11040	COG3773	Cell wall hydrolase
FIU87_11060	COG3853	Toxic anion resistance protein (TelA)
FIU87_11070	COG1012	belongs to the aldehyde dehydrogenase family
FIU87_11080	COG0671	phosphoesterase, PA-phosphatase related
FIU87_11085	COG4548	von Willebrand factor, type A
FIU87_11090	COG0714	Associated with various cellular activities
FIU87_11095	COG0861	Integral membrane protein TerC family
FIU87_11100	COG0534	Mate efflux family protein
FIU87_11110	COG2340	Cysteine-rich secretory protein family
FIU87_11120	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU87_11125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIU87_11130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU87_11135	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FIU87_11145	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU87_11165	COG3842	ATPase activity
FIU87_11170	COG4120	Belongs to the binding-protein-dependent transport system permease family
FIU87_11195	COG1136	(ABC) transporter
FIU87_11205	COG0412	Dienelactone hydrolase
FIU87_11250	COG1051	belongs to the nudix hydrolase family
FIU87_11275	COG3327	negative regulation of DNA-templated transcription, initiation
FIU87_11280	COG0183	Belongs to the thiolase family
FIU87_11285	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU87_11290	COG1012	belongs to the aldehyde dehydrogenase family
FIU87_11295	COG1024	Enoyl-CoA hydratase
FIU87_11300	COG1024	Enoyl-CoA hydratase
FIU87_11325	COG3396	Phenylacetate-CoA oxygenase
FIU87_11330	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FIU87_11340	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FIU87_11345	COG0400	carboxylic ester hydrolase activity
FIU87_11360	COG1876	peptidase activity
FIU87_11365	COG0432	Pfam Uncharacterised protein family UPF0047
FIU87_11370	COG0813	purine-nucleoside phosphorylase activity
FIU87_11400	COG4479	Belongs to the UPF0346 family
FIU87_11410	COG1509	lysine 2,3-aminomutase activity
FIU87_11415	COG3829	transcription factor binding
FIU87_11420	COG0456	acetyltransferase
FIU87_11425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU87_11430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FIU87_11435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FIU87_11440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU87_11450	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU87_11450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU87_11475	COG3275	phosphorelay sensor kinase activity
FIU87_11485	COG1966	Carbon starvation protein
FIU87_11490	COG5002	protein histidine kinase activity
FIU87_11510	COG0596	Alpha beta hydrolase
FIU87_11510	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU87_11535	COG2755	lipolytic protein G-D-S-L family
FIU87_11540	COG1999	signal sequence binding
FIU87_11560	COG0714	Associated with various cellular activities
FIU87_11575	COG1131	(ABC) transporter
FIU87_11595	COG1307	EDD domain protein, DegV family
FIU87_11605	COG2135	peptidase activity
FIU87_11615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FIU87_11620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIU87_11630	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FIU87_11640	COG2521	methyltransferase
FIU87_11640	COG2136	Putative SAM-dependent methyltransferase
FIU87_11650	COG1413	lyase activity
FIU87_11655	COG0488	(ABC) transporter
FIU87_11660	COG1418	mRNA catabolic process
FIU87_11670	COG1307	EDD domain protein, DegV family
FIU87_11675	COG0386	Belongs to the glutathione peroxidase family
FIU87_11690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIU87_11695	COG2226	methyltransferase
FIU87_11710	COG0390	transport system, permease component
FIU87_11715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU87_11720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU87_11720	COG0551	DNA topoisomerase type I activity
FIU87_11730	COG1278	Cold shock
FIU87_11745	COG0328	RNA-DNA hybrid ribonuclease activity
FIU87_11750	COG0328	RNA-DNA hybrid ribonuclease activity
FIU87_11765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU87_11785	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FIU87_11795	COG1755	Isoprenylcysteine carboxyl methyltransferase
FIU87_11800	COG3424	synthase
FIU87_11835	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FIU87_11840	COG1199	ATP-dependent helicase activity
FIU87_11855	COG0116	Belongs to the methyltransferase superfamily
FIU87_11875	COG4474	Belongs to the UPF0398 family
FIU87_11885	COG3359	exonuclease
FIU87_11890	COG1111	helicase
FIU87_11890	COG1205	dead DEAH box helicase
FIU87_11905	COG0071	Belongs to the small heat shock protein (HSP20) family
FIU87_11945	COG3331	DNA recombination
FIU87_11950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU87_11950	COG4499	WXG100 protein secretion system (Wss), protein YukC
FIU87_11960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIU87_11965	COG3935	DnaD domain protein
FIU87_11970	COG0017	Asparaginyl-tRNA synthetase
FIU87_11990	COG1199	ATP-dependent helicase activity
FIU87_11990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU87_11995	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FIU87_12010	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FIU87_12010	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FIU87_12015	COG0617	tRNA 3'-terminal CCA addition
FIU87_12020	COG0438	transferase activity, transferring glycosyl groups
FIU87_12025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FIU87_12030	COG1803	Methylglyoxal synthase
FIU87_12035	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIU87_12040	COG1694	Mazg nucleotide pyrophosphohydrolase
FIU87_12045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FIU87_12050	COG2738	Putative neutral zinc metallopeptidase
FIU87_12060	COG4347	Protein of unknown function (DUF1405)
FIU87_12070	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FIU87_12075	COG0723	plastoquinol--plastocyanin reductase activity
FIU87_12085	COG5582	Belongs to the UPF0302 family
FIU87_12090	COG0457	Tetratricopeptide repeat
FIU87_12100	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIU87_12105	COG0287	Prephenate dehydrogenase
FIU87_12110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU87_12115	COG0159	tryptophan synthase activity
FIU87_12120	COG0133	tryptophan synthase activity
FIU87_12125	COG0135	phosphoribosylanthranilate isomerase activity
FIU87_12130	COG0134	indole-3-glycerol-phosphate synthase activity
FIU87_12135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU87_12145	COG4401	Chorismate mutase type I
FIU87_12150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIU87_12155	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIU87_12160	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU87_12165	COG0105	UTP biosynthetic process
FIU87_12170	COG0142	geranyltranstransferase activity
FIU87_12175	COG2226	methyltransferase
FIU87_12180	COG0142	geranyltranstransferase activity
FIU87_12190	COG0302	gtp cyclohydrolase
FIU87_12195	COG0776	regulation of translation
FIU87_12200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FIU87_12245	COG1304	FMN binding
FIU87_12250	COG0539	negative regulation of cytoplasmic translation
FIU87_12275	COG2959	enzyme of heme biosynthesis
FIU87_12280	COG3409	Peptidoglycan-binding domain 1 protein
FIU87_12280	COG3773	Cell wall hydrolase
FIU87_12285	COG2339	peptidase activity
FIU87_12290	COG0252	asparaginase activity
FIU87_12295	COG0492	ferredoxin-NADP+ reductase activity
FIU87_12300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU87_12305	COG4862	establishment of competence for transformation
FIU87_12310	COG0789	Transcriptional regulator
FIU87_12315	COG1408	metallophosphoesterase
FIU87_12325	COG1388	LysM domain
FIU87_12330	COG1266	CAAX protease self-immunity
FIU87_12335	COG0514	ATP-dependent DNA helicase (RecQ)
FIU87_12340	COG4955	Helix-turn-helix domain
FIU87_12345	COG1141	Ferredoxin
FIU87_12350	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FIU87_12355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU87_12365	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_12370	COG2610	gluconate transmembrane transporter activity
FIU87_12380	COG1595	DNA-templated transcription, initiation
FIU87_12395	COG5002	protein histidine kinase activity
FIU87_12400	COG0745	RESPONSE REGULATOR receiver
FIU87_12405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU87_12410	COG1333	cytochrome c biogenesis protein
FIU87_12415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU87_12420	COG1187	pseudouridine synthase activity
FIU87_12425	COG0700	Nucleoside recognition
FIU87_12430	COG2715	membrane protein required for spore maturation
FIU87_12435	COG1686	Belongs to the peptidase S11 family
FIU87_12440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FIU87_12455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FIU87_12465	COG1547	Domain of unknown function (DUF309)
FIU87_12475	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FIU87_12480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU87_12480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU87_12485	COG0307	riboflavin synthase, alpha
FIU87_12490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU87_12490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU87_12495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIU87_12520	COG0697	spore germination
FIU87_12535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU87_12555	COG1609	Transcriptional regulator
FIU87_12560	COG1874	Beta-galactosidase
FIU87_12570	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FIU87_12575	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FIU87_12595	COG1653	transport
FIU87_12610	COG2172	sigma factor antagonist activity
FIU87_12620	COG1686	Belongs to the peptidase S11 family
FIU87_12640	COG4974	Belongs to the 'phage' integrase family
FIU87_12650	COG0735	belongs to the Fur family
FIU87_12655	COG1300	Membrane
FIU87_12660	COG1379	DNA repair
FIU87_12665	COG0494	nUDIX hydrolase
FIU87_12675	COG0667	Aldo Keto reductase
FIU87_12685	COG0753	catalase activity
FIU87_12745	COG3340	Belongs to the peptidase S51 family
FIU87_12755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FIU87_12760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FIU87_12765	COG0183	Belongs to the thiolase family
FIU87_12770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU87_12780	COG1742	UPF0060 membrane protein
FIU87_12820	COG1073	alpha beta
FIU87_12835	COG0596	Alpha beta hydrolase
FIU87_12840	COG0778	Nitroreductase
FIU87_12850	COG3403	YqcI/YcgG family
FIU87_12855	COG1280	lysine exporter protein (LysE YggA)
FIU87_12860	COG1115	amino acid carrier protein
FIU87_12875	COG0454	-acetyltransferase
FIU87_12880	COG1476	TRANSCRIPTIONal
FIU87_12915	COG2755	lipolytic protein G-D-S-L family
FIU87_12925	COG0577	efflux transmembrane transporter activity
FIU87_12930	COG1136	(ABC) transporter
FIU87_12935	COG2205	protein histidine kinase activity
FIU87_12940	COG0745	RESPONSE REGULATOR receiver
FIU87_12955	COG1193	negative regulation of DNA recombination
FIU87_12960	COG2323	membrane
FIU87_12965	COG0681	Belongs to the peptidase S26 family
FIU87_13010	COG0534	Mate efflux family protein
FIU87_13015	COG4608	Belongs to the ABC transporter superfamily
FIU87_13025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU87_13030	COG0601	transmembrane transport
FIU87_13035	COG0747	negative chemotaxis
FIU87_13050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU87_13100	COG0110	maltose O-acetyltransferase activity
FIU87_13120	COG3615	Tellurite resistance protein tehB
FIU87_13120	COG0500	methyltransferase
FIU87_13185	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU87_13205	COG0300	oxidoreductase activity
FIU87_13210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU87_13225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIU87_13235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIU87_13255	COG4941	Belongs to the sigma-70 factor family
FIU87_13265	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU87_13275	COG2130	NADP-dependent
FIU87_13285	COG1595	DNA-templated transcription, initiation
FIU87_13290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIU87_13295	COG1366	Belongs to the anti-sigma-factor antagonist family
FIU87_13300	COG0785	Cytochrome C biogenesis protein
FIU87_13305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU87_13320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FIU87_13330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FIU87_13335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FIU87_13380	COG4187	Peptidase family M20/M25/M40
FIU87_13385	COG1902	pentaerythritol trinitrate reductase activity
FIU87_13420	COG0584	glycerophosphoryl diester phosphodiesterase
FIU87_13430	COG0702	epimerase
FIU87_13450	COG1051	belongs to the nudix hydrolase family
FIU87_13455	COG0018	arginyl-trna synthetase
FIU87_13500	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIU87_13515	COG1620	l-lactate permease
FIU87_13520	COG0039	L-malate dehydrogenase activity
FIU87_13535	COG0346	lactoylglutathione lyase activity
FIU87_13545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU87_13560	COG1136	(ABC) transporter
FIU87_13570	COG1595	DNA-templated transcription, initiation
FIU87_13575	COG1234	tRNA 3'-trailer cleavage
FIU87_13600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU87_13610	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIU87_13615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU87_13620	COG0346	lactoylglutathione lyase activity
FIU87_13640	COG1376	ErfK ybiS ycfS ynhG family protein
FIU87_13645	COG4129	membrane
FIU87_13650	COG1164	Oligoendopeptidase f
FIU87_13655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU87_13680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU87_13685	COG1126	abc transporter atp-binding protein
FIU87_13690	COG0765	amino acid transport
FIU87_13695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU87_13700	COG1595	DNA-templated transcription, initiation
FIU87_13705	COG5002	protein histidine kinase activity
FIU87_13725	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU87_13725	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU87_13730	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU87_13740	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU87_13745	COG0022	dehydrogenase e1 component
FIU87_13750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FIU87_13755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU87_13760	COG3426	butyrate kinase activity
FIU87_13770	COG0280	phosphate acetyltransferase
FIU87_13775	COG3829	transcription factor binding
FIU87_13775	COG3290	protein histidine kinase activity
FIU87_13785	COG0584	glycerophosphoryl diester phosphodiesterase
FIU87_13790	COG3093	addiction module antidote protein HigA
FIU87_13795	COG0745	RESPONSE REGULATOR receiver
FIU87_13800	COG0750	zinc metalloprotease
FIU87_13805	COG0497	DNA recombination
FIU87_13815	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FIU87_13820	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIU87_13825	COG0142	geranyltranstransferase activity
FIU87_13830	COG1722	exodeoxyribonuclease VII activity
FIU87_13835	COG1570	exodeoxyribonuclease VII activity
FIU87_13840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FIU87_13845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU87_13850	COG1302	Protein conserved in bacteria
FIU87_13855	COG0439	Biotin carboxylase
FIU87_13860	COG0511	ligase activity, forming carbon-carbon bonds
FIU87_13900	COG3854	ATPases associated with a variety of cellular activities
FIU87_13910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU87_13915	COG0366	Alpha amylase catalytic
FIU87_13925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU87_13930	COG0006	proline dipeptidase activity
FIU87_13935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIU87_13945	COG3872	metal-dependent enzyme
FIU87_13955	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIU87_13960	COG1321	iron dependent repressor
FIU87_13980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU87_13990	COG0095	Lipoate-protein ligase
FIU87_13995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU87_14010	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIU87_14015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU87_14020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIU87_14045	COG3708	Transcriptional regulator
FIU87_14045	COG2207	Transcriptional regulator
FIU87_14055	COG2226	methyltransferase
FIU87_14060	COG0456	acetyltransferase
FIU87_14065	COG2140	Oxalate decarboxylase
FIU87_14085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU87_14115	COG4970	Tfp pilus assembly protein FimT
FIU87_14120	COG4537	Required for transformation and DNA binding
FIU87_14125	COG1459	type II secretion system
FIU87_14130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU87_14160	COG4608	Belongs to the ABC transporter superfamily
FIU87_14165	COG0791	NLP P60 protein
FIU87_14170	COG4948	Mandelate Racemase Muconate Lactonizing
FIU87_14175	COG1619	proteins homologs of microcin C7 resistance protein MccF
FIU87_14180	COG4166	transmembrane transport
FIU87_14185	COG0444	Belongs to the ABC transporter superfamily
FIU87_14190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU87_14195	COG0601	transmembrane transport
FIU87_14200	COG2362	D-Aminopeptidase
FIU87_14205	COG0693	protein deglycase activity
FIU87_14210	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FIU87_14215	COG4191	Histidine kinase
FIU87_14250	COG1393	Belongs to the ArsC family
FIU87_14265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU87_14280	COG0011	TIGRFAM Protein of
FIU87_14295	COG1368	sulfuric ester hydrolase activity
FIU87_14305	COG1940	carbohydrate kinase activity
FIU87_14315	COG0697	spore germination
FIU87_14320	COG0705	Rhomboid family
FIU87_14320	COG0457	Tetratricopeptide repeat
FIU87_14325	COG0840	transmembrane signaling receptor activity
FIU87_14340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU87_14350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FIU87_14385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIU87_14390	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FIU87_14395	COG0640	Transcriptional regulator
FIU87_14400	COG0659	secondary active sulfate transmembrane transporter activity
FIU87_14405	COG0704	Plays a role in the regulation of phosphate uptake
FIU87_14410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU87_14415	COG0581	inorganic phosphate transmembrane transporter activity
FIU87_14420	COG0573	inorganic phosphate transmembrane transporter activity
FIU87_14425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FIU87_14435	COG0477	Major facilitator Superfamily
FIU87_14445	COG0205	6-phosphofructokinase activity
FIU87_14450	COG2839	Protein conserved in bacteria
FIU87_14455	COG1283	sodium-dependent phosphate transmembrane transporter activity
FIU87_14460	COG5521	maltodextrose utilization protein MalA
FIU87_14470	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FIU87_14475	COG4709	membrane
FIU87_14480	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FIU87_14490	COG0735	belongs to the Fur family
FIU87_14495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU87_14500	COG1121	(ABC) transporter
FIU87_14505	COG5002	protein histidine kinase activity
FIU87_14515	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FIU87_14530	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIU87_14535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FIU87_14540	COG2384	SAM-dependent methyltransferase
FIU87_14550	COG1960	acyl-CoA dehydrogenase activity
FIU87_14560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU87_14565	COG0358	DNA primase activity
FIU87_14570	COG1671	Belongs to the UPF0178 family
FIU87_14575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FIU87_14580	COG0517	IMP dehydrogenase activity
FIU87_14585	COG0751	glycine-tRNA ligase activity
FIU87_14590	COG0752	glycyl-tRNA synthetase alpha subunit
FIU87_14595	COG1381	Involved in DNA repair and RecF pathway recombination
FIU87_14605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIU87_14610	COG0295	cytidine deaminase activity
FIU87_14625	COG1480	7TM receptor with intracellular HD hydrolase
FIU87_14630	COG1702	phosphate starvation-inducible protein PhoH
FIU87_14650	COG4864	UPF0365 protein
FIU87_14655	COG1030	water channel activity
FIU87_14660	COG1610	YqeY-like protein
FIU87_14665	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FIU87_14675	COG1283	sodium-dependent phosphate transmembrane transporter activity
FIU87_14680	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FIU87_14685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU87_14690	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIU87_14695	COG2264	protein methyltransferase activity
FIU87_14705	COG0443	Heat shock 70 kDa protein
FIU87_14715	COG1420	regulation of RNA biosynthetic process
FIU87_14720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU87_14735	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU87_14750	COG1466	dna polymerase III delta subunit
FIU87_14760	COG0658	competence protein
FIU87_14760	COG2333	competence protein COMEC
FIU87_14765	COG2131	deaminase
FIU87_14770	COG1596	polysaccharide export
FIU87_14770	COG1555	photosystem II stabilization
FIU87_14775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIU87_14780	COG2226	methyltransferase
FIU87_14785	COG0799	negative regulation of ribosome biogenesis
FIU87_14790	COG1713	HD superfamily hydrolase involved in NAD metabolism
FIU87_14795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FIU87_14800	COG1534	Rna-binding protein
FIU87_14810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FIU87_14815	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FIU87_14825	COG0688	phosphatidylethanolamine metabolic process
FIU87_14840	COG1191	sigma factor activity
FIU87_14845	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIU87_14875	COG1174	glycine betaine transport
FIU87_14880	COG1125	glycine betaine transport
FIU87_14880	COG0517	IMP dehydrogenase activity
FIU87_14895	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FIU87_14900	COG0626	cystathionine gamma-synthase activity
FIU87_14905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIU87_14910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FIU87_14915	COG2226	methyltransferase
FIU87_14935	COG3328	transposase activity
FIU87_14945	COG0768	penicillin binding
FIU87_14950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU87_14955	COG0572	uridine kinase
FIU87_14980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIU87_14985	COG1959	2 iron, 2 sulfur cluster binding
FIU87_14990	COG3906	Belongs to the UPF0473 family
FIU87_14995	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIU87_15000	COG4472	Bacterial protein of unknown function (DUF965)
FIU87_15010	COG0628	permease
FIU87_15015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU87_15020	COG1012	belongs to the aldehyde dehydrogenase family
FIU87_15025	COG3835	regulator
FIU87_15085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIU87_15095	COG0482	sulfurtransferase activity
FIU87_15100	COG1104	cysteine desulfurase activity
FIU87_15105	COG1959	2 iron, 2 sulfur cluster binding
FIU87_15110	COG2364	Membrane
FIU87_15115	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIU87_15125	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FIU87_15145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FIU87_15150	COG0124	histidyl-tRNA synthetase
FIU87_15160	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU87_15165	COG1490	D-aminoacyl-tRNA deacylase activity
FIU87_15170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU87_15185	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FIU87_15185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIU87_15195	COG0494	nUDIX hydrolase
FIU87_15200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FIU87_15210	COG0697	spore germination
FIU87_15220	COG5416	Lipopolysaccharide assembly protein A domain
FIU87_15225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FIU87_15230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU87_15230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU87_15240	COG2244	polysaccharide biosynthetic process
FIU87_15245	COG2323	membrane
FIU87_15255	COG1862	Preprotein translocase
FIU87_15265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIU87_15275	COG2255	four-way junction helicase activity
FIU87_15295	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FIU87_15305	COG1388	LysM domain
FIU87_15315	COG0157	Belongs to the NadC ModD family
FIU87_15320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FIU87_15325	COG1104	cysteine desulfurase activity
FIU87_15330	COG1827	regulation of RNA biosynthetic process
FIU87_15335	COG0077	Prephenate dehydratase
FIU87_15340	COG4492	Belongs to the UPF0735 family
FIU87_15345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIU87_15350	COG3290	protein histidine kinase activity
FIU87_15355	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIU87_15360	COG2868	ribosomal protein
FIU87_15370	COG1530	ribonuclease E activity
FIU87_15375	COG1994	Peptidase M50
FIU87_15380	COG0739	heme binding
FIU87_15385	COG2894	cell division
FIU87_15390	COG0850	regulation of cytokinetic process
FIU87_15395	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FIU87_15400	COG1792	Involved in formation and maintenance of cell shape
FIU87_15405	COG1077	Cell shape determining protein MreB Mrl
FIU87_15420	COG2003	Belongs to the UPF0758 family
FIU87_15425	COG0424	maF-like protein
FIU87_15450	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FIU87_15470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU87_15500	COG1595	DNA-templated transcription, initiation
FIU87_15510	COG3706	GGDEF domain
FIU87_15510	COG0745	RESPONSE REGULATOR receiver
FIU87_15515	COG0285	dihydrofolate synthase activity
FIU87_15520	COG0189	ligase activity
FIU87_15525	COG0189	ligase activity
FIU87_15535	COG0525	valine-tRNA ligase activity
FIU87_15540	COG0840	transmembrane signaling receptor activity
FIU87_15545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIU87_15550	COG1388	LysM domain
FIU87_15550	COG1388	LysM domain
FIU87_15555	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FIU87_15560	COG0113	porphobilinogen synthase activity
FIU87_15570	COG0181	hydroxymethylbilane synthase activity
FIU87_15575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU87_15590	COG1126	abc transporter atp-binding protein
FIU87_15600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU87_15605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIU87_15610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIU87_15615	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FIU87_15620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU87_15625	COG1067	ATP-dependent peptidase activity
FIU87_15625	COG0470	DNA polymerase III
FIU87_15635	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIU87_15640	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIU87_15645	COG0457	Tetratricopeptide repeat
FIU87_15645	COG1477	protein flavinylation
FIU87_15655	COG0622	Phosphoesterase
FIU87_15660	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIU87_15665	COG5401	PFAM Sporulation and spore germination
FIU87_15675	COG1846	Transcriptional regulator
FIU87_15680	COG2197	response regulator
FIU87_15685	COG0824	Thioesterase
FIU87_15690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIU87_15695	COG1053	succinate dehydrogenase
FIU87_15700	COG2009	succinate dehydrogenase
FIU87_15705	COG1719	4-vinyl reductase, 4VR
FIU87_15715	COG0322	excinuclease ABC activity
FIU87_15720	COG3118	belongs to the thioredoxin family
FIU87_15725	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FIU87_15730	COG2086	electron transfer activity
FIU87_15735	COG1024	Enoyl-CoA hydratase
FIU87_15740	COG1309	transcriptional regulator
FIU87_15745	COG0318	PFAM AMP-dependent synthetase and ligase
FIU87_15750	COG3766	membrane
FIU87_15755	COG1193	negative regulation of DNA recombination
FIU87_15760	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FIU87_15760	COG1796	DNA polymerase
FIU87_15765	COG1286	toxin biosynthetic process
FIU87_15770	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FIU87_15775	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIU87_15780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU87_15780	COG0072	phenylalanine-tRNA ligase activity
FIU87_15785	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FIU87_15790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU87_15805	COG1363	Peptidase, m42
FIU87_15820	COG0398	Pfam SNARE associated Golgi protein
FIU87_15825	COG3326	Membrane
FIU87_15835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FIU87_15840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FIU87_15845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIU87_15855	COG1597	lipid kinase activity
FIU87_15860	COG3611	Membrane attachment protein
FIU87_15865	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIU87_15875	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FIU87_15880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU87_15890	COG1971	Probably functions as a manganese efflux pump
FIU87_15895	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIU87_15900	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU87_15900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU87_15905	COG0330	HflC and HflK could
FIU87_15915	COG5002	protein histidine kinase activity
FIU87_15920	COG0745	RESPONSE REGULATOR receiver
FIU87_15930	COG0039	L-malate dehydrogenase activity
FIU87_15935	COG0538	isocitrate dehydrogenase activity
FIU87_15940	COG0372	Belongs to the citrate synthase family
FIU87_15950	COG0628	permease
FIU87_15955	COG4086	secreted protein
FIU87_15960	COG3030	protein affecting phage T7 exclusion by the F plasmid
FIU87_15970	COG0205	6-phosphofructokinase activity
FIU87_15975	COG0825	malonyl-CoA metabolic process
FIU87_15980	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIU87_15985	COG1725	Transcriptional regulator
FIU87_15990	COG0281	malic enzyme
FIU87_15995	COG0587	DNA-directed DNA polymerase activity
FIU87_16010	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FIU87_16030	COG4109	DRTGG domain
FIU87_16055	COG0006	proline dipeptidase activity
FIU87_16065	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_16070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FIU87_16090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIU87_16095	COG0827	DNA restriction-modification system
FIU87_16100	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FIU87_16105	COG3874	Sporulation protein YtfJ
FIU87_16115	COG1714	RDD family
FIU87_16120	COG0616	signal peptide processing
FIU87_16125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIU87_16130	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FIU87_16135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU87_16145	COG0301	tRNA thio-modification
FIU87_16150	COG1104	cysteine desulfurase activity
FIU87_16155	COG1114	Component of the transport system for branched-chain amino acids
FIU87_16160	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FIU87_16165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FIU87_16170	COG1309	transcriptional regulator
FIU87_16175	COG1956	GAF domain-containing protein
FIU87_16180	COG0626	cystathionine gamma-synthase activity
FIU87_16185	COG2203	Gaf domain
FIU87_16185	COG2199	diguanylate cyclase activity
FIU87_16195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FIU87_16230	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FIU87_16245	COG0456	acetyltransferase
FIU87_16260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU87_16265	COG0454	-acetyltransferase
FIU87_16270	COG0517	IMP dehydrogenase activity
FIU87_16275	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIU87_16295	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FIU87_16295	COG1605	Chorismate mutase
FIU87_16300	COG0849	cell division
FIU87_16305	COG3118	belongs to the thioredoxin family
FIU87_16310	COG4980	gas vesicle protein
FIU87_16315	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FIU87_16320	COG2309	aminopeptidase activity
FIU87_16325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU87_16335	COG1674	ftsk spoiiie
FIU87_16340	COG4848	Belongs to the UPF0354 family
FIU87_16345	COG4412	M6 family metalloprotease domain protein
FIU87_16345	COG1404	Belongs to the peptidase S8 family
FIU87_16350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU87_16360	COG0840	transmembrane signaling receptor activity
FIU87_16375	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FIU87_16380	COG1363	Peptidase, m42
FIU87_16390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU87_16395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIU87_16405	COG0510	thiamine kinase activity
FIU87_16410	COG1523	belongs to the glycosyl hydrolase 13 family
FIU87_16420	COG1346	cytolysis
FIU87_16425	COG1380	Effector of murein hydrolase LrgA
FIU87_16435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIU87_16445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU87_16455	COG1131	(ABC) transporter
FIU87_16460	COG1349	DNA-binding transcription factor activity
FIU87_16465	COG1187	pseudouridine synthase activity
FIU87_16470	COG2244	polysaccharide biosynthetic process
FIU87_16480	COG2081	HI0933 family
FIU87_16515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU87_16520	COG0495	leucyl-tRNA aminoacylation
FIU87_16525	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_16530	COG2610	gluconate transmembrane transporter activity
FIU87_16535	COG3829	transcription factor binding
FIU87_16535	COG3290	protein histidine kinase activity
FIU87_16550	COG0326	Molecular chaperone. Has ATPase activity
FIU87_16560	COG2814	Major facilitator Superfamily
FIU87_16575	COG1242	4 iron, 4 sulfur cluster binding
FIU87_16580	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FIU87_16590	COG2267	carboxylic ester hydrolase activity
FIU87_16595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIU87_16600	COG0671	phosphoesterase, PA-phosphatase related
FIU87_16605	COG0438	transferase activity, transferring glycosyl groups
FIU87_16605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIU87_16610	COG0488	(ABC) transporter
FIU87_16615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIU87_16630	COG1506	peptidase
FIU87_16635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU87_16640	COG1116	anion transmembrane transporter activity
FIU87_16645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU87_16650	COG0494	nUDIX hydrolase
FIU87_16665	COG4824	toxin secretion phage lysis holin
FIU87_16670	COG0783	Belongs to the Dps family
FIU87_16685	COG0701	Predicted permease
FIU87_16690	COG1854	S-ribosylhomocysteine lyase activity
FIU87_16695	COG0288	reversible hydration of carbon dioxide
FIU87_16700	COG0523	cobalamin synthesis protein
FIU87_16710	COG0523	cobalamin synthesis protein
FIU87_16715	COG1271	oxidase subunit
FIU87_16720	COG1294	oxidase, subunit
FIU87_16735	COG4948	Mandelate Racemase Muconate Lactonizing
FIU87_16740	COG0318	PFAM AMP-dependent synthetase and ligase
FIU87_16745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FIU87_16750	COG0596	Alpha beta hydrolase
FIU87_16760	COG1169	isochorismate synthase
FIU87_16765	COG1575	Belongs to the MenA family. Type 1 subfamily
FIU87_16770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU87_16785	COG0058	SHG alpha-glucan phosphorylase activity
FIU87_16790	COG0297	glycogen (starch) synthase activity
FIU87_16795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIU87_16935	COG3859	Proton-coupled thiamine transporter YuaJ
FIU87_16950	COG1285	pathogenesis
FIU87_16960	COG2247	cell wall binding repeat
FIU87_16960	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU87_16965	COG1404	Belongs to the peptidase S8 family
FIU87_16965	COG4412	M6 family metalloprotease domain protein
FIU87_16970	COG1215	transferase activity, transferring glycosyl groups
FIU87_16975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU87_17000	COG0489	protein tyrosine kinase activity
FIU87_17010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU87_17010	COG2190	(PTS) system
FIU87_17010	COG1263	PTS System
FIU87_17015	COG3876	Protein conserved in bacteria
FIU87_17020	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU87_17025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIU87_17030	COG4572	Cation transport regulator
FIU87_17045	COG2197	response regulator
FIU87_17050	COG4585	Histidine kinase
FIU87_17075	COG1404	Belongs to the peptidase S8 family
FIU87_17085	COG2132	Multicopper oxidase
FIU87_17090	COG2814	Major facilitator Superfamily
FIU87_17105	COG3279	Response regulator of the LytR AlgR family
FIU87_17120	COG3243	poly(R)-hydroxyalkanoic acid synthase
FIU87_17130	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_17135	COG1278	Cold shock
FIU87_17140	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FIU87_17160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU87_17180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU87_17180	COG2111	Na H antiporter
FIU87_17185	COG2111	Na H antiporter
FIU87_17190	COG1006	Multisubunit Na H antiporter MnhC subunit
FIU87_17195	COG0651	ATP synthesis coupled electron transport
FIU87_17200	COG1863	multisubunit Na H antiporter MnhE subunit
FIU87_17205	COG2212	antiporter activity
FIU87_17210	COG1320	monovalent cation:proton antiporter activity
FIU87_17215	COG1979	alcohol dehydrogenase
FIU87_17220	COG2155	Conserved Protein
FIU87_17225	COG1098	S1 RNA binding domain
FIU87_17230	COG0436	Aminotransferase
FIU87_17235	COG1522	sequence-specific DNA binding
FIU87_17240	COG2267	carboxylic ester hydrolase activity
FIU87_17250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIU87_17260	COG2032	superoxide dismutase activity
FIU87_17280	COG5018	Exonuclease
FIU87_17285	COG2814	Major facilitator Superfamily
FIU87_17295	COG2050	protein possibly involved in aromatic compounds catabolism
FIU87_17305	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_17325	COG2723	6-phospho-beta-galactosidase activity
FIU87_17330	COG0395	ABC-type sugar transport system, permease component
FIU87_17340	COG1653	transport
FIU87_17345	COG1609	Transcriptional regulator
FIU87_17350	COG1131	(ABC) transporter
FIU87_17360	COG1595	DNA-templated transcription, initiation
FIU87_17370	COG1131	(ABC) transporter
FIU87_17375	COG0772	Belongs to the SEDS family
FIU87_17380	COG0772	Belongs to the SEDS family
FIU87_17455	COG1268	BioY protein
FIU87_17460	COG2056	Na+-H+ antiporter family
FIU87_17465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU87_17475	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FIU87_17480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU87_17485	COG3584	3D domain protein
FIU87_17500	COG1252	NADH dehydrogenase
FIU87_17515	COG0316	Belongs to the HesB IscA family
FIU87_17520	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIU87_17525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIU87_17535	COG1252	NADH dehydrogenase
FIU87_17540	COG4837	Protein of unknown function (DUF1462)
FIU87_17545	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FIU87_17550	COG0083	homoserine kinase activity
FIU87_17555	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FIU87_17560	COG0460	homoserine dehydrogenase
FIU87_17565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU87_17570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIU87_17575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FIU87_17580	COG0647	UMP catabolic process
FIU87_17585	COG2445	Protein of unknown function DUF86
FIU87_17590	COG2200	EAL domain
FIU87_17590	COG2199	diguanylate cyclase activity
FIU87_17590	COG3287	FIST C domain
FIU87_17605	COG4470	Protein conserved in bacteria
FIU87_17615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIU87_17620	COG0739	heme binding
FIU87_17630	COG0733	neurotransmitter:sodium symporter activity
FIU87_17635	COG1757	Na H antiporter
FIU87_17645	COG3328	transposase activity
FIU87_17650	COG3377	Domain of unknown function (DUF1805)
FIU87_17655	COG0737	Belongs to the 5'-nucleotidase family
FIU87_17660	COG1801	Protein of unknown function DUF72
FIU87_17670	COG1131	(ABC) transporter
FIU87_17690	COG0719	Fe-S assembly protein
FIU87_17695	COG0822	iron-sulfur transferase activity
FIU87_17700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU87_17705	COG0719	Fe-S assembly protein
FIU87_17710	COG0396	ATPase activity
FIU87_17720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIU87_17725	COG1464	Belongs to the NlpA lipoprotein family
FIU87_17730	COG2011	ABC-type metal ion transport system permease component
FIU87_17735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FIU87_17740	COG1597	lipid kinase activity
FIU87_17750	COG0477	Major facilitator Superfamily
FIU87_17755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU87_17760	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FIU87_17770	COG0509	glycine decarboxylation via glycine cleavage system
FIU87_17775	COG1393	Belongs to the ArsC family
FIU87_17780	COG1960	acyl-CoA dehydrogenase activity
FIU87_17785	COG0183	Belongs to the thiolase family
FIU87_17790	COG1024	Enoyl-CoA hydratase
FIU87_17790	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU87_17810	COG5577	PFAM Coat F domain
FIU87_17825	COG1120	ATPase activity
FIU87_17835	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_17840	COG0750	zinc metalloprotease
FIU87_17845	COG0730	response to heat
FIU87_17850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU87_17850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU87_17855	COG0425	Belongs to the sulfur carrier protein TusA family
FIU87_17855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU87_17870	COG2210	Belongs to the sulfur carrier protein TusA family
FIU87_17875	COG0425	Belongs to the sulfur carrier protein TusA family
FIU87_17880	COG1937	Protein conserved in bacteria
FIU87_17890	COG1940	carbohydrate kinase activity
FIU87_17920	COG0673	inositol 2-dehydrogenase activity
FIU87_17940	COG0673	inositol 2-dehydrogenase activity
FIU87_17945	COG3459	Glycosyltransferase 36 associated
FIU87_17955	COG0395	ABC-type sugar transport system, permease component
FIU87_17975	COG0395	ABC-type sugar transport system, permease component
FIU87_17980	COG1175	transmembrane transport
FIU87_18000	COG1132	(ABC) transporter
FIU87_18045	COG1028	Short-chain dehydrogenase reductase Sdr
FIU87_18050	COG5002	protein histidine kinase activity
FIU87_18055	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FIU87_18060	COG0557	exoribonuclease II activity
FIU87_18065	COG1647	Serine aminopeptidase, S33
FIU87_18100	COG0681	Belongs to the peptidase S26 family
FIU87_18120	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIU87_18125	COG0148	phosphopyruvate hydratase activity
FIU87_18130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FIU87_18160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FIU87_18190	COG0740	serine-type endopeptidase activity
FIU87_18195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU87_18200	COG1481	regulation of sporulation
FIU87_18205	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FIU87_18210	COG1660	Displays ATPase and GTPase activities
FIU87_18215	COG1051	belongs to the nudix hydrolase family
FIU87_18220	COG0492	ferredoxin-NADP+ reductase activity
FIU87_18225	COG0457	Tetratricopeptide repeat
FIU87_18230	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIU87_18230	COG0140	phosphoribosyl-ATP diphosphatase activity
FIU87_18235	COG0107	imidazoleglycerol-phosphate synthase activity
FIU87_18240	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIU87_18245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU87_18250	COG0131	Imidazoleglycerol-phosphate dehydratase
FIU87_18255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU87_18265	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FIU87_18270	COG0110	maltose O-acetyltransferase activity
FIU87_18275	COG0546	phosphoglycolate phosphatase activity
FIU87_18280	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FIU87_18290	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FIU87_18295	COG1950	PFAM Membrane protein of
FIU87_18305	COG3595	metallopeptidase activity
FIU87_18315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FIU87_18320	COG0556	nucleotide-excision repair
FIU87_18345	COG1595	DNA-templated transcription, initiation
FIU87_18355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FIU87_18365	COG1070	Carbohydrate kinase
FIU87_18370	COG2610	gluconate transmembrane transporter activity
FIU87_18375	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FIU87_18380	COG1737	Transcriptional regulator
FIU87_18430	COG0697	spore germination
FIU87_18435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU87_18440	COG3409	Peptidoglycan-binding domain 1 protein
FIU87_18440	COG0793	Belongs to the peptidase S41A family
FIU87_18450	COG0739	heme binding
FIU87_18455	COG2177	Part of the ABC transporter FtsEX involved in
FIU87_18460	COG2884	Cell division ATP-binding protein ftsE
FIU87_18465	COG2010	Cytochrome c
FIU87_18470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FIU87_18475	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FIU87_18480	COG0653	protein targeting
FIU87_18485	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU87_18485	COG2247	cell wall binding repeat
FIU87_18490	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU87_18500	COG1516	flagellar protein fliS
FIU87_18505	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FIU87_18510	COG1334	flagellar protein FlaG
FIU87_18520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU87_18535	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FIU87_18540	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FIU87_18550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU87_18555	COG1256	bacterial-type flagellum assembly
FIU87_18555	COG4786	Flagellar basal body rod
FIU87_18575	COG1040	competence protein
FIU87_18580	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FIU87_18585	COG1307	EDD domain protein, DegV family
FIU87_18590	COG2197	response regulator
FIU87_18600	COG1739	Uncharacterized protein family UPF0029
FIU87_18605	COG1316	TRANSCRIPTIONal
FIU87_18610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU87_18615	COG1215	transferase activity, transferring glycosyl groups
FIU87_18630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FIU87_18635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FIU87_18665	COG0438	transferase activity, transferring glycosyl groups
FIU87_18675	COG2247	cell wall binding repeat
FIU87_18675	COG2385	sporulation resulting in formation of a cellular spore
FIU87_18685	COG3103	Sh3 type 3 domain protein
FIU87_18685	COG4991	sh3 domain protein
FIU87_18685	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU87_18710	COG1388	LysM domain
FIU87_18710	COG0791	NLP P60 protein
FIU87_18715	COG2247	cell wall binding repeat
FIU87_18715	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU87_18720	COG2385	sporulation resulting in formation of a cellular spore
FIU87_18720	COG2247	cell wall binding repeat
FIU87_18725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FIU87_18725	COG0463	Glycosyl transferase, family 2
FIU87_18730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FIU87_18745	COG1134	teichoic acid transport
FIU87_18750	COG1682	transport, permease protein
FIU87_18755	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FIU87_18760	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FIU87_18770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FIU87_18790	COG1316	TRANSCRIPTIONal
FIU87_18795	COG4464	protein tyrosine phosphatase activity
FIU87_18800	COG3764	Sortase (surface protein transpeptidase)
FIU87_18820	COG4715	Zinc finger, swim domain protein
FIU87_18825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIU87_18840	COG0629	single-stranded DNA binding
FIU87_18855	COG3012	SEC-C Motif Domain Protein
FIU87_18880	COG0673	inositol 2-dehydrogenase activity
FIU87_18885	COG4753	response regulator
FIU87_18885	COG2207	Transcriptional regulator
FIU87_18890	COG2972	Histidine kinase
FIU87_18915	COG3300	MHYT domain
FIU87_18915	COG5001	Diguanylate cyclase
FIU87_18920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU87_18940	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FIU87_18945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIU87_18955	COG1523	belongs to the glycosyl hydrolase 13 family
FIU87_18965	COG0653	protein targeting
FIU87_18995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIU87_19000	COG2226	methyltransferase
FIU87_19015	COG1595	DNA-templated transcription, initiation
FIU87_19035	COG1078	dGTPase activity
FIU87_19045	COG2962	Rard protein
FIU87_19050	COG0456	acetyltransferase
FIU87_19070	COG1404	Belongs to the peptidase S8 family
FIU87_19075	COG1879	ABC-type sugar transport system periplasmic component
FIU87_19085	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU87_19090	COG1129	ABC transporter
FIU87_19095	COG2390	Transcriptional regulator
FIU87_19115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU87_19120	COG1360	Flagellar Motor Protein
FIU87_19130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU87_19140	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU87_19140	COG2247	cell wall binding repeat
FIU87_19165	COG1619	proteins homologs of microcin C7 resistance protein MccF
FIU87_19180	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU87_19180	COG2247	cell wall binding repeat
FIU87_19210	COG1404	Belongs to the peptidase S8 family
FIU87_19215	COG0745	RESPONSE REGULATOR receiver
FIU87_19235	COG1388	LysM domain
FIU87_19235	COG0791	NLP P60 protein
FIU87_19300	COG2610	gluconate transmembrane transporter activity
FIU87_19305	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIU87_19310	COG1929	Belongs to the glycerate kinase type-1 family
FIU87_19315	COG3835	regulator
FIU87_19360	COG0737	Belongs to the 5'-nucleotidase family
FIU87_19385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FIU87_19435	COG1525	nuclease
FIU87_19460	COG1309	transcriptional regulator
FIU87_19485	COG0640	Transcriptional regulator
FIU87_19565	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FIU87_19570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIU87_19585	COG1216	Glycosyl transferase, family 2
FIU87_19600	COG0438	transferase activity, transferring glycosyl groups
FIU87_19620	COG0363	glucosamine-6-phosphate deaminase activity
FIU87_19630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU87_19635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU87_19650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FIU87_19655	COG1086	Polysaccharide biosynthesis protein
FIU87_19660	COG0489	protein tyrosine kinase activity
FIU87_19665	COG3944	biosynthesis protein
FIU87_19695	COG4786	Flagellar basal body rod
FIU87_19700	COG4786	Flagellar basal body rod
FIU87_19720	COG1077	Cell shape determining protein MreB Mrl
FIU87_19725	COG1609	Transcriptional regulator
FIU87_19750	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FIU87_19755	COG1595	DNA-templated transcription, initiation
FIU87_19785	COG1131	(ABC) transporter
FIU87_19805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIU87_19820	COG5002	protein histidine kinase activity
FIU87_19820	COG2176	DNA-directed DNA polymerase activity
FIU87_19830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU87_19855	COG1136	(ABC) transporter
FIU87_19860	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FIU87_19865	COG2059	Chromate
FIU87_19870	COG2059	Chromate
FIU87_19875	COG0405	Gamma-glutamyltransferase
FIU87_19880	COG0739	heme binding
FIU87_19885	COG2385	sporulation resulting in formation of a cellular spore
FIU87_19890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIU87_19900	COG4836	Membrane
FIU87_19905	COG1007	ATP synthesis coupled electron transport
FIU87_19915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU87_19920	COG0713	ATP synthesis coupled electron transport
FIU87_19925	COG0839	Belongs to the complex I subunit 6 family
FIU87_19945	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU87_19950	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU87_19960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIU87_19965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIU87_19970	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIU87_19975	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIU87_19980	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIU87_19990	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIU87_19995	COG0356	it plays a direct role in the translocation of protons across the membrane
FIU87_20005	COG1404	Belongs to the peptidase S8 family
FIU87_20010	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FIU87_20015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU87_20025	COG0698	ribose 5-phosphate isomerase
FIU87_20030	COG0840	transmembrane signaling receptor activity
FIU87_20040	COG1971	Probably functions as a manganese efflux pump
FIU87_20045	COG0009	L-threonylcarbamoyladenylate synthase
FIU87_20065	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU87_20085	COG1435	thymidine kinase activity
FIU87_20095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FIU87_20100	COG1494	fructose-1,6-bisphosphatase
FIU87_20115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIU87_20120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU87_20125	COG0191	fructose-bisphosphate aldolase activity
FIU87_20130	COG2204	response regulator
FIU87_20135	COG4821	SIS domain
FIU87_20140	COG0504	CTP synthase activity
FIU87_20150	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU87_20150	COG1703	isobutyryl-CoA mutase activity
FIU87_20150	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU87_20155	COG3226	Transcriptional regulator
FIU87_20160	COG1960	acyl-CoA dehydrogenase activity
FIU87_20165	COG1960	acyl-CoA dehydrogenase activity
FIU87_20170	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU87_20175	COG0183	Belongs to the thiolase family
FIU87_20180	COG0247	lactate metabolic process
FIU87_20180	COG2181	nitrate reductase activity
FIU87_20185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU87_20190	COG4294	response to UV
FIU87_20205	COG0018	arginyl-trna synthetase
FIU87_20215	COG0010	Belongs to the arginase family
FIU87_20220	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FIU87_20225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU87_20240	COG4325	translation initiation factor activity
FIU87_20245	COG0596	Alpha beta hydrolase
FIU87_20250	COG3465	dGTPase activity
FIU87_20255	COG1078	dGTPase activity
FIU87_20270	COG0280	phosphate acetyltransferase
FIU87_20285	COG2363	Small membrane protein
FIU87_20300	COG2322	membrane
FIU87_20305	COG0840	transmembrane signaling receptor activity
FIU87_20315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FIU87_20320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIU87_20325	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FIU87_20330	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIU87_20345	COG2261	transglycosylase associated protein
FIU87_20365	COG0778	Nitroreductase
FIU87_20370	COG1309	transcriptional regulator
FIU87_20375	COG1511	domain protein
FIU87_20375	COG0842	Transport permease protein
FIU87_20380	COG1131	(ABC) transporter
FIU87_20390	COG2031	fatty acid transporter
FIU87_20405	COG1621	beta-fructofuranosidase activity
FIU87_20415	COG1263	PTS System
FIU87_20415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU87_20420	COG3711	transcriptional antiterminator
FIU87_20425	COG2190	(PTS) system
FIU87_20430	COG3153	acetyltransferase
FIU87_20430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU87_20435	COG0561	phosphatase activity
FIU87_20465	COG2190	(PTS) system
FIU87_20465	COG1263	PTS System
FIU87_20465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU87_20480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU87_20480	COG0551	DNA topoisomerase type I activity
FIU87_20485	COG0488	(ABC) transporter
FIU87_20525	COG1017	nitric oxide dioxygenase activity
FIU87_20525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU87_20540	COG2267	carboxylic ester hydrolase activity
FIU87_20570	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FIU87_20595	COG1737	Transcriptional regulator
FIU87_20610	COG1316	TRANSCRIPTIONal
FIU87_20615	COG1316	TRANSCRIPTIONal
FIU87_20630	COG4977	sequence-specific DNA binding
FIU87_20640	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FIU87_20645	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FIU87_20650	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FIU87_20660	COG0698	ribose 5-phosphate isomerase
FIU87_20670	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FIU87_20690	COG4869	propanediol catabolic process
FIU87_20695	COG2390	Transcriptional regulator
FIU87_20715	COG1744	ABC transporter substrate-binding protein PnrA-like
FIU87_20720	COG1187	pseudouridine synthase activity
FIU87_20725	COG1120	ATPase activity
FIU87_20730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU87_20735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU87_20740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU87_20745	COG3328	transposase activity
FIU87_20755	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU87_20760	COG1840	ABC-type Fe3 transport system, periplasmic component
FIU87_20795	COG1984	allophanate hydrolase subunit 2
FIU87_20800	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FIU87_20805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FIU87_20810	COG1914	H( )-stimulated, divalent metal cation uptake system
FIU87_20820	COG3706	GGDEF domain
FIU87_20855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU87_20860	COG0697	spore germination
FIU87_20865	COG2207	Transcriptional regulator
FIU87_20865	COG0662	Cupin 2, conserved barrel domain protein
FIU87_20905	COG2378	regulation of single-species biofilm formation
FIU87_20920	COG1131	(ABC) transporter
FIU87_20930	COG1132	(ABC) transporter
FIU87_20940	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FIU87_20945	COG2169	Transcriptional regulator
FIU87_20960	COG3706	GGDEF domain
FIU87_20965	COG3153	acetyltransferase
FIU87_20980	COG1595	DNA-templated transcription, initiation
FIU87_21000	COG0640	Transcriptional regulator
FIU87_21005	COG0038	chloride channel
FIU87_21045	COG1307	EDD domain protein, DegV family
FIU87_21050	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FIU87_21055	COG1349	DNA-binding transcription factor activity
FIU87_21100	COG0778	Nitroreductase
FIU87_21130	COG0789	Transcriptional regulator
FIU87_21205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU87_21210	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FIU87_21215	COG4853	Protein conserved in bacteria
FIU87_21220	COG4863	YycH protein
FIU87_21225	COG5002	protein histidine kinase activity
FIU87_21230	COG0745	RESPONSE REGULATOR receiver
FIU87_21240	COG1196	nuclear chromosome segregation
FIU87_21240	COG0741	lytic transglycosylase activity
FIU87_21240	COG0739	heme binding
FIU87_21270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIU87_21275	COG0305	Participates in initiation and elongation during chromosome replication
FIU87_21280	COG0359	binds to the 23S rRNA
FIU87_21285	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FIU87_21290	COG4241	membrane
FIU87_21295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FIU87_21305	COG0360	Binds together with S18 to 16S ribosomal RNA
FIU87_21310	COG0012	GTP binding
FIU87_21315	COG0471	metal ion transport
FIU87_21320	COG4481	Protein conserved in bacteria
FIU87_21325	COG0668	transmembrane transport
FIU87_21330	COG3949	Membrane
FIU87_21345	COG1475	DNA binding
FIU87_21350	COG1192	Involved in chromosome partitioning
FIU87_21355	COG1475	DNA binding
FIU87_21365	COG0445	tRNA wobble uridine modification
FIU87_21370	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FIU87_21375	COG1847	R3H domain protein