locus-tag	class	description
LDP77_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LDP77_00010	COG0592	DNA-directed DNA polymerase activity
LDP77_00015	COG2501	S4 domain
LDP77_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDP77_00025	COG0187	DNA topoisomerase II activity
LDP77_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LDP77_00065	COG0516	GMP reductase activity
LDP77_00065	COG0517	IMP dehydrogenase activity
LDP77_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LDP77_00095	COG1428	Deoxynucleoside kinase
LDP77_00100	COG1428	Deoxynucleoside kinase
LDP77_00105	COG1388	LysM domain
LDP77_00105	COG3858	chitin binding
LDP77_00110	COG1335	isochorismatase
LDP77_00115	COG0590	tRNA wobble adenosine to inosine editing
LDP77_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LDP77_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LDP77_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LDP77_00240	COG1982	Orn Lys Arg decarboxylase major
LDP77_00245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LDP77_00250	COG3870	Protein conserved in bacteria
LDP77_00255	COG0470	DNA polymerase III
LDP77_00260	COG1774	PSP1 C-terminal conserved region
LDP77_00265	COG4467	Involved in initiation control of chromosome replication
LDP77_00270	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LDP77_00275	COG2827	Endonuclease containing a URI domain
LDP77_00280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LDP77_00285	COG2002	toxin-antitoxin pair type II binding
LDP77_00295	COG0084	hydrolase, TatD family'
LDP77_00305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LDP77_00315	COG4466	Protein conserved in bacteria
LDP77_00330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDP77_00335	COG0251	oxidation-reduction process
LDP77_00340	COG2088	sporulation resulting in formation of a cellular spore
LDP77_00345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LDP77_00360	COG0193	aminoacyl-tRNA hydrolase activity
LDP77_00370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LDP77_00375	COG2002	toxin-antitoxin pair type II binding
LDP77_00380	COG2244	polysaccharide biosynthetic process
LDP77_00385	COG3956	TIGRFAM MazG family protein
LDP77_00390	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LDP77_00405	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LDP77_00410	COG1098	S1 RNA binding domain
LDP77_00430	COG2304	oxidoreductase activity
LDP77_00435	COG0515	serine threonine protein kinase
LDP77_00440	COG0037	tRNA processing
LDP77_00445	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LDP77_00450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LDP77_00455	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LDP77_00460	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LDP77_00465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LDP77_00470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LDP77_00475	COG0512	Glutamine amidotransferase of anthranilate synthase
LDP77_00480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDP77_00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LDP77_00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LDP77_00495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LDP77_00520	COG3880	PFAM UvrB UvrC protein
LDP77_00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
LDP77_00530	COG0542	response to heat
LDP77_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LDP77_00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LDP77_00545	COG4956	integral membrane protein (PIN domain superfamily)
LDP77_00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LDP77_00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDP77_00565	COG1045	serine acetyltransferase
LDP77_00570	COG0215	cysteine-tRNA ligase activity
LDP77_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDP77_00585	COG3688	RNA-binding protein containing a PIN domain
LDP77_00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LDP77_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDP77_00605	COG0250	Participates in transcription elongation, termination and antitermination
LDP77_00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LDP77_00615	COG0081	regulation of translation
LDP77_00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LDP77_00625	COG0222	ribosome binding
LDP77_00630	COG2813	Specifically methylates the guanine in position
LDP77_00635	COG0085	RNA polymerase activity
LDP77_00645	COG1358	cellular component organization or biogenesis
LDP77_00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LDP77_00655	COG0049	tRNA binding
LDP77_00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDP77_00670	COG0051	transcription antitermination factor activity, RNA binding
LDP77_00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LDP77_00680	COG0088	Forms part of the polypeptide exit tunnel
LDP77_00685	COG0089	rRNA binding
LDP77_00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LDP77_00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LDP77_00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LDP77_00710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LDP77_00715	COG0255	Belongs to the universal ribosomal protein uL29 family
LDP77_00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LDP77_00725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LDP77_00740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LDP77_00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LDP77_00760	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LDP77_00765	COG1841	ribosomal large subunit assembly
LDP77_00775	COG0201	protein transport
LDP77_00780	COG0563	adenylate kinase activity
LDP77_00785	COG0024	Methionine aminopeptidase
LDP77_00790	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LDP77_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LDP77_00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LDP77_00810	COG0202	RNA polymerase activity
LDP77_00815	COG0203	ribosomal protein L17
LDP77_00820	COG1122	ATPase activity
LDP77_00825	COG1122	ATPase activity
LDP77_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LDP77_00835	COG0101	tRNA pseudouridine synthase activity
LDP77_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LDP77_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
LDP77_00860	COG0489	protein tyrosine kinase activity
LDP77_00865	COG0583	DNA-binding transcription factor activity
LDP77_00875	COG2194	sulfuric ester hydrolase activity
LDP77_00880	COG0726	polysaccharide deacetylase
LDP77_00960	COG1595	DNA-templated transcription, initiation
LDP77_00965	COG5662	AntiSigma factor
LDP77_00970	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LDP77_00980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDP77_00985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDP77_00995	COG0791	NLP P60 protein
LDP77_00995	COG1388	LysM domain
LDP77_00995	COG3103	Sh3 type 3 domain protein
LDP77_01000	COG2213	PTS system mannitol-specific
LDP77_01000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP77_01005	COG3711	transcriptional antiterminator
LDP77_01010	COG0246	Mannitol dehydrogenase
LDP77_01020	COG1376	ErfK ybiS ycfS ynhG family protein
LDP77_01025	COG1970	mechanosensitive ion channel activity
LDP77_01030	COG1368	sulfuric ester hydrolase activity
LDP77_01050	COG1177	transmembrane transport
LDP77_01055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LDP77_01065	COG0745	RESPONSE REGULATOR receiver
LDP77_01070	COG5002	protein histidine kinase activity
LDP77_01085	COG3976	FMN-binding domain protein
LDP77_01085	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LDP77_01090	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDP77_01095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDP77_01100	COG0513	Belongs to the DEAD box helicase family
LDP77_01105	COG4294	response to UV
LDP77_01110	COG0705	Rhomboid family
LDP77_01115	COG0736	holo-[acyl-carrier-protein] synthase activity
LDP77_01120	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LDP77_01125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDP77_01130	COG0864	Transcriptional regulator
LDP77_01135	COG2337	Toxic component of a toxin-antitoxin (TA) module
LDP77_01140	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_01145	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_01150	COG2172	sigma factor antagonist activity
LDP77_01155	COG2208	phosphoserine phosphatase activity
LDP77_01160	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_01170	COG1191	sigma factor activity
LDP77_01175	COG2208	phosphoserine phosphatase activity
LDP77_01180	COG2183	response to ionizing radiation
LDP77_01275	COG0802	atpase or kinase
LDP77_01280	COG1214	PFAM Peptidase M22, glycoprotease
LDP77_01285	COG0456	acetyltransferase
LDP77_01295	COG0488	(ABC) transporter
LDP77_01300	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LDP77_01305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDP77_01310	COG0805	protein transport
LDP77_01320	COG1266	CAAX protease self-immunity
LDP77_01325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LDP77_01335	COG0714	Associated with various cellular activities
LDP77_01340	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LDP77_01345	COG1305	Transglutaminase-like
LDP77_01350	COG0519	Catalyzes the synthesis of GMP from XMP
LDP77_01350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDP77_01355	COG2252	PERMEase
LDP77_01410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LDP77_01415	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LDP77_01420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LDP77_01425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LDP77_01430	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LDP77_01435	COG0047	phosphoribosylformylglycinamidine synthase activity
LDP77_01440	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LDP77_01445	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LDP77_01450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LDP77_01455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LDP77_01460	COG0138	bifunctional purine biosynthesis protein purh
LDP77_01465	COG0151	Belongs to the GarS family
LDP77_01475	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LDP77_01480	COG4496	protein, YerC YecD
LDP77_01485	COG0423	glycine-tRNA ligase activity
LDP77_01495	COG0210	DNA helicase
LDP77_01505	COG4851	CamS sex pheromone cAM373 precursor
LDP77_01515	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LDP77_01520	COG0154	amidase activity
LDP77_01530	COG1597	lipid kinase activity
LDP77_01540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_01550	COG0166	Belongs to the GPI family
LDP77_01555	COG1744	ABC transporter substrate-binding protein PnrA-like
LDP77_01560	COG3852	Histidine kinase
LDP77_01565	COG0024	Methionine aminopeptidase
LDP77_01570	COG2706	6-phosphogluconolactonase activity
LDP77_01580	COG4978	Transcriptional regulator
LDP77_01580	COG0789	Transcriptional regulator
LDP77_01585	COG2814	Major facilitator Superfamily
LDP77_01595	COG1876	peptidase activity
LDP77_01600	COG1126	abc transporter atp-binding protein
LDP77_01605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP77_01610	COG0765	amino acid transport
LDP77_01615	COG0765	amino acid transport
LDP77_01620	COG1113	amino acid transport
LDP77_01625	COG2733	membrane
LDP77_01630	COG3212	peptidase
LDP77_01635	COG3212	peptidase
LDP77_01640	COG3850	Histidine kinase
LDP77_01640	COG5002	protein histidine kinase activity
LDP77_01645	COG0745	RESPONSE REGULATOR receiver
LDP77_01650	COG2205	protein histidine kinase activity
LDP77_01655	COG0745	RESPONSE REGULATOR receiver
LDP77_01660	COG2311	Membrane
LDP77_01675	COG0671	phosphoesterase, PA-phosphatase related
LDP77_01680	COG1764	response to oxidative stress
LDP77_01685	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LDP77_01695	COG2259	Doxx family
LDP77_01700	COG0693	protein deglycase activity
LDP77_01710	COG2318	DinB family
LDP77_01720	COG1115	amino acid carrier protein
LDP77_01735	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LDP77_01740	COG0598	Magnesium transport protein CorA
LDP77_01745	COG3290	protein histidine kinase activity
LDP77_01770	COG4191	Histidine kinase
LDP77_01775	COG0513	Belongs to the DEAD box helicase family
LDP77_01795	COG4842	Belongs to the WXG100 family
LDP77_01800	COG5417	Belongs to the EsaB family
LDP77_01805	COG4499	WXG100 protein secretion system (Wss), protein YukC
LDP77_01810	COG0433	COG0433 Predicted ATPase
LDP77_01810	COG1674	ftsk spoiiie
LDP77_01815	COG1511	domain protein
LDP77_01830	COG2356	endonuclease I
LDP77_01840	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDP77_01855	COG0488	(ABC) transporter
LDP77_01865	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LDP77_01875	COG1959	2 iron, 2 sulfur cluster binding
LDP77_01880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDP77_01880	COG1017	nitric oxide dioxygenase activity
LDP77_01890	COG0693	protein deglycase activity
LDP77_01895	COG2340	Cysteine-rich secretory protein family
LDP77_01900	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LDP77_01905	COG4840	Belongs to the UPF0435 family
LDP77_01910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDP77_01915	COG4980	gas vesicle protein
LDP77_01920	COG1295	ribonuclease BN
LDP77_01925	COG2217	Heavy metal translocating P-type atpase
LDP77_01935	COG0640	Transcriptional regulator
LDP77_01945	COG0477	Major facilitator Superfamily
LDP77_01950	COG3479	Phenolic acid decarboxylase
LDP77_01960	COG3871	stress protein (general stress protein 26)
LDP77_01965	COG0387	Pfam Sodium calcium exchanger
LDP77_01975	COG0535	radical SAM domain protein
LDP77_01995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDP77_02005	COG1113	amino acid transport
LDP77_02010	COG5002	protein histidine kinase activity
LDP77_02030	COG1090	epimerase
LDP77_02040	COG4221	oxidoreductase activity
LDP77_02060	COG1988	membrane-bound metal-dependent
LDP77_02065	COG1194	a g-specific adenine glycosylase
LDP77_02075	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_02090	COG3557	Belongs to the UPF0374 family
LDP77_02095	COG1132	(ABC) transporter
LDP77_02100	COG4129	membrane
LDP77_02110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDP77_02115	COG4555	ABC transporter
LDP77_02135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LDP77_02140	COG0735	belongs to the Fur family
LDP77_02255	COG3382	B3 4 domain protein
LDP77_02270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LDP77_02275	COG2766	serine protein kinase
LDP77_02290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LDP77_02305	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LDP77_02315	COG1968	undecaprenyl-diphosphatase activity
LDP77_02320	COG1301	dicarboxylic acid transport
LDP77_02325	COG0628	permease
LDP77_02330	COG0586	Pfam SNARE associated Golgi protein
LDP77_02335	COG2217	Heavy metal translocating P-type atpase
LDP77_02340	COG0531	amino acid
LDP77_02355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LDP77_02360	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LDP77_02365	COG3842	ATPase activity
LDP77_02370	COG1175	transmembrane transport
LDP77_02385	COG0584	glycerophosphoryl diester phosphodiesterase
LDP77_02400	COG4948	Mandelate Racemase Muconate Lactonizing
LDP77_02445	COG3584	3D domain protein
LDP77_02445	COG1388	LysM domain
LDP77_02450	COG1876	peptidase activity
LDP77_02460	COG3103	Sh3 type 3 domain protein
LDP77_02470	COG0456	acetyltransferase
LDP77_02470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_02475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDP77_02495	COG1609	Transcriptional regulator
LDP77_02500	COG2814	Major facilitator Superfamily
LDP77_02505	COG0673	inositol 2-dehydrogenase activity
LDP77_02530	COG1609	Transcriptional regulator
LDP77_02545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_02550	COG1522	sequence-specific DNA binding
LDP77_02565	COG2814	Major facilitator Superfamily
LDP77_02570	COG1309	transcriptional regulator
LDP77_02575	COG1187	pseudouridine synthase activity
LDP77_02590	COG1942	4-Oxalocrotonate Tautomerase
LDP77_02595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LDP77_02600	COG0747	negative chemotaxis
LDP77_02620	COG0084	hydrolase, TatD family'
LDP77_02625	COG2962	Rard protein
LDP77_02635	COG0628	permease
LDP77_02650	COG0604	alcohol dehydrogenase
LDP77_02655	COG1620	l-lactate permease
LDP77_02665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LDP77_02670	COG0840	transmembrane signaling receptor activity
LDP77_02675	COG0564	pseudouridine synthase activity
LDP77_02685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDP77_02690	COG1376	ErfK ybiS ycfS ynhG family protein
LDP77_02695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDP77_02695	COG3153	acetyltransferase
LDP77_02700	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LDP77_02705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LDP77_02715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDP77_02720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDP77_02725	COG1268	BioY protein
LDP77_02735	COG2719	SpoVR family
LDP77_02745	COG1959	2 iron, 2 sulfur cluster binding
LDP77_02750	COG0604	alcohol dehydrogenase
LDP77_02760	COG1126	abc transporter atp-binding protein
LDP77_02765	COG0765	amino acid transport
LDP77_02770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP77_02775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDP77_02780	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDP77_02790	COG0352	thiamine-phosphate diphosphorylase activity
LDP77_02795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDP77_02810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LDP77_02815	COG0351	phosphomethylpyrimidine kinase
LDP77_02830	COG0702	epimerase
LDP77_02835	COG1253	flavin adenine dinucleotide binding
LDP77_02850	COG3842	ATPase activity
LDP77_02855	COG2508	Transcriptional regulator
LDP77_02870	COG0189	ligase activity
LDP77_02875	COG0189	ligase activity
LDP77_02885	COG3679	Belongs to the UPF0342 family
LDP77_02890	COG0561	phosphatase activity
LDP77_02900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LDP77_02905	COG0318	PFAM AMP-dependent synthetase and ligase
LDP77_02910	COG1024	Enoyl-CoA hydratase
LDP77_02925	COG4152	abc transporter atp-binding protein
LDP77_02930	COG1668	transmembrane transport
LDP77_02940	COG3481	metal-dependent phosphohydrolase, HD sub domain
LDP77_02950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDP77_02975	COG1846	Transcriptional regulator
LDP77_02990	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LDP77_02995	COG1695	Transcriptional regulator
LDP77_03000	COG2153	protein acetylation
LDP77_03005	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LDP77_03005	COG2755	lipolytic protein G-D-S-L family
LDP77_03010	COG0537	adenosine 5'-monophosphoramidase activity
LDP77_03015	COG1131	(ABC) transporter
LDP77_03020	COG4473	ABC transporter
LDP77_03030	COG1473	amidohydrolase
LDP77_03035	COG0671	phosphoesterase, PA-phosphatase related
LDP77_03040	COG3069	C4-dicarboxylate transmembrane transporter activity
LDP77_03045	COG2329	Antibiotic biosynthesis monooxygenase
LDP77_03050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDP77_03055	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LDP77_03060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LDP77_03065	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LDP77_03070	COG1309	transcriptional regulator
LDP77_03075	COG0768	penicillin binding
LDP77_03085	COG2972	Histidine kinase
LDP77_03100	COG1234	tRNA 3'-trailer cleavage
LDP77_03105	COG0095	Lipoate-protein ligase
LDP77_03110	COG0318	PFAM AMP-dependent synthetase and ligase
LDP77_03115	COG1024	Enoyl-CoA hydratase
LDP77_03230	COG0501	Belongs to the peptidase M48B family
LDP77_03235	COG2224	Isocitrate lyase
LDP77_03245	COG0823	Involved in the tonB-independent uptake of proteins
LDP77_03245	COG4946	Tricorn protease homolog
LDP77_03245	COG1506	peptidase
LDP77_03250	COG0398	Pfam SNARE associated Golgi protein
LDP77_03255	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_03260	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LDP77_03265	COG1074	ATP-dependent DNA helicase activity
LDP77_03270	COG0420	3'-5' exonuclease activity
LDP77_03275	COG0419	ATPase involved in DNA repair
LDP77_03280	COG1403	HNH endonuclease
LDP77_03315	COG2311	Membrane
LDP77_03330	COG0367	asparagine synthase
LDP77_03345	COG1562	ergosterol biosynthetic process
LDP77_03350	COG0347	Belongs to the P(II) protein family
LDP77_03355	COG0004	ammonium transporteR
LDP77_03360	COG0366	Alpha amylase catalytic
LDP77_03360	COG1874	Beta-galactosidase
LDP77_03365	COG1609	Transcriptional regulator
LDP77_03370	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_03375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LDP77_03380	COG4187	Peptidase family M20/M25/M40
LDP77_03385	COG0833	amino acid
LDP77_03390	COG3829	transcription factor binding
LDP77_03395	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_03400	COG1666	GTP binding
LDP77_03405	COG2996	Protein conserved in bacteria
LDP77_03415	COG1307	EDD domain protein, DegV family
LDP77_03420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_03435	COG0561	phosphatase activity
LDP77_03440	COG2151	metal-sulfur cluster biosynthetic enzyme
LDP77_03445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDP77_03450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LDP77_03455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LDP77_03460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LDP77_03480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LDP77_03495	COG0542	response to heat
LDP77_03510	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LDP77_03515	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LDP77_03520	COG2084	Dehydrogenase
LDP77_03530	COG2267	carboxylic ester hydrolase activity
LDP77_03550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDP77_03555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LDP77_03560	COG5504	Zn-dependent protease
LDP77_03565	COG0444	Belongs to the ABC transporter superfamily
LDP77_03570	COG4608	Belongs to the ABC transporter superfamily
LDP77_03580	COG0601	transmembrane transport
LDP77_03595	COG0180	Tryptophanyl-tRNA synthetase
LDP77_03600	COG4166	transmembrane transport
LDP77_03605	COG0601	transmembrane transport
LDP77_03610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDP77_03615	COG0444	Belongs to the ABC transporter superfamily
LDP77_03620	COG4608	Belongs to the ABC transporter superfamily
LDP77_03625	COG0456	acetyltransferase
LDP77_03630	COG1113	amino acid transport
LDP77_03640	COG0531	amino acid
LDP77_03645	COG1393	Belongs to the ArsC family
LDP77_03650	COG0583	DNA-binding transcription factor activity
LDP77_03665	COG0861	Integral membrane protein TerC family
LDP77_03675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDP77_03685	COG1164	Oligoendopeptidase f
LDP77_03695	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LDP77_03700	COG2346	COG2346, Truncated hemoglobins
LDP77_03705	COG0741	lytic transglycosylase activity
LDP77_03710	COG4116	CYTH
LDP77_03720	COG2357	RelA SpoT domain protein
LDP77_03730	COG0564	pseudouridine synthase activity
LDP77_03740	COG2239	Acts as a magnesium transporter
LDP77_03745	COG0569	domain protein
LDP77_03745	COG0475	glutathione-regulated potassium exporter activity
LDP77_03810	COG0210	DNA helicase
LDP77_03820	COG2323	membrane
LDP77_03825	COG2153	protein acetylation
LDP77_03835	COG2382	esterase
LDP77_03845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LDP77_03855	COG1737	Transcriptional regulator
LDP77_03860	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LDP77_03865	COG1070	Carbohydrate kinase
LDP77_03870	COG1953	Uracil, thiamine, allantoin
LDP77_03890	COG1522	sequence-specific DNA binding
LDP77_03900	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LDP77_03915	COG3142	Participates in the control of copper homeostasis
LDP77_03920	COG1113	amino acid transport
LDP77_03930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP77_03935	COG1309	transcriptional regulator
LDP77_03940	COG3711	transcriptional antiterminator
LDP77_03940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP77_03945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LDP77_03950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LDP77_03955	COG1447	Phosphotransferase system cellobiose-specific component IIA
LDP77_03960	COG1486	melibiose metabolic process
LDP77_03965	COG3275	phosphorelay sensor kinase activity
LDP77_03970	COG3279	Response regulator of the LytR AlgR family
LDP77_03980	COG1346	cytolysis
LDP77_03990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDP77_03995	COG0243	molybdopterin cofactor binding
LDP77_04000	COG2223	nitrite transmembrane transporter activity
LDP77_04005	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LDP77_04020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDP77_04035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDP77_04035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LDP77_04045	COG3527	Alpha-acetolactate decarboxylase
LDP77_04050	COG0028	Belongs to the TPP enzyme family
LDP77_04060	COG4895	conserved protein (DUF2196)
LDP77_04070	COG1733	regulation of RNA biosynthetic process
LDP77_04075	COG2814	Major facilitator Superfamily
LDP77_04080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_04100	COG3052	prosthetic group binding
LDP77_04115	COG0784	Response regulator, receiver
LDP77_04120	COG4191	Histidine kinase
LDP77_04125	COG2066	Belongs to the glutaminase family
LDP77_04130	COG1115	amino acid carrier protein
LDP77_04135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDP77_04145	COG4297	protein containing double-stranded beta helix domain
LDP77_04150	COG0531	amino acid
LDP77_04160	COG1607	acyl-coa hydrolase
LDP77_04165	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LDP77_04180	COG0390	transport system, permease component
LDP77_04185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDP77_04200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDP77_04205	COG1136	(ABC) transporter
LDP77_04210	COG0577	efflux transmembrane transporter activity
LDP77_04220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LDP77_04225	COG1063	alcohol dehydrogenase
LDP77_04240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDP77_04245	COG0833	amino acid
LDP77_04255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LDP77_04260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDP77_04270	COG0861	Integral membrane protein TerC family
LDP77_04280	COG1301	dicarboxylic acid transport
LDP77_04285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDP77_04290	COG3290	protein histidine kinase activity
LDP77_04330	COG1476	TRANSCRIPTIONal
LDP77_04340	COG1368	sulfuric ester hydrolase activity
LDP77_04355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP77_04360	COG2040	homocysteine
LDP77_04365	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDP77_04380	COG2851	Citrate transporter
LDP77_04385	COG3290	protein histidine kinase activity
LDP77_04390	COG4565	transcriptional regulatory protein
LDP77_04395	COG3181	Tripartite tricarboxylate transporter family receptor
LDP77_04405	COG0583	DNA-binding transcription factor activity
LDP77_04410	COG3180	Ammonia monooxygenase
LDP77_04415	COG2226	methyltransferase
LDP77_04425	COG0517	IMP dehydrogenase activity
LDP77_04425	COG4175	Glycine betaine
LDP77_04430	COG2113	Glycine betaine
LDP77_04435	COG1309	transcriptional regulator
LDP77_04440	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_04455	COG0531	amino acid
LDP77_04460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDP77_04465	COG1464	Belongs to the NlpA lipoprotein family
LDP77_04470	COG2011	ABC-type metal ion transport system permease component
LDP77_04475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LDP77_04490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_04500	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LDP77_04505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP77_04510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP77_04535	COG1737	Transcriptional regulator
LDP77_04540	COG1263	PTS System
LDP77_04540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP77_04550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDP77_04555	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LDP77_04560	COG1116	anion transmembrane transporter activity
LDP77_04565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDP77_04570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LDP77_04580	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LDP77_04585	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LDP77_04590	COG1733	regulation of RNA biosynthetic process
LDP77_04625	COG1511	domain protein
LDP77_04635	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LDP77_04640	COG1733	regulation of RNA biosynthetic process
LDP77_04645	COG4221	oxidoreductase activity
LDP77_04645	COG0604	alcohol dehydrogenase
LDP77_04645	COG3321	synthase
LDP77_04645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDP77_04650	COG1132	(ABC) transporter
LDP77_04655	COG1132	(ABC) transporter
LDP77_04665	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDP77_04670	COG3162	membrane
LDP77_04680	COG1414	Transcriptional regulator
LDP77_04685	COG0656	L-ascorbic acid biosynthetic process
LDP77_04690	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LDP77_04695	COG1846	Transcriptional regulator
LDP77_04700	COG1566	PFAM secretion protein HlyD family protein
LDP77_04705	COG2814	Major facilitator Superfamily
LDP77_04710	COG0655	NAD(P)H dehydrogenase (quinone) activity
LDP77_04725	COG1609	Transcriptional regulator
LDP77_04730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDP77_04740	COG1129	ABC transporter
LDP77_04745	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDP77_04750	COG1879	ABC-type sugar transport system periplasmic component
LDP77_04755	COG3584	3D domain protein
LDP77_04755	COG3583	domain protein
LDP77_04760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LDP77_04765	COG1653	transport
LDP77_04810	COG0745	RESPONSE REGULATOR receiver
LDP77_04815	COG5002	protein histidine kinase activity
LDP77_04825	COG2267	carboxylic ester hydrolase activity
LDP77_04835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LDP77_04850	COG0402	S-adenosylhomocysteine deaminase activity
LDP77_04855	COG2252	PERMEase
LDP77_04860	COG1609	Transcriptional regulator
LDP77_04865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LDP77_04870	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_04880	COG0710	3-dehydroquinate dehydratase activity
LDP77_04890	COG1263	PTS System
LDP77_04890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP77_04895	COG0366	Alpha amylase catalytic
LDP77_04900	COG2188	Transcriptional regulator
LDP77_04905	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LDP77_04910	COG1984	allophanate hydrolase subunit 2
LDP77_04915	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LDP77_04920	COG1914	H( )-stimulated, divalent metal cation uptake system
LDP77_04925	COG1272	protein, Hemolysin III
LDP77_04940	COG0778	Nitroreductase
LDP77_04945	COG0628	permease
LDP77_04970	COG2271	Major facilitator Superfamily
LDP77_04975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDP77_04980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDP77_04985	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_04995	COG0402	S-adenosylhomocysteine deaminase activity
LDP77_05000	COG1278	Cold shock
LDP77_05005	COG2910	NAD(P)H-binding
LDP77_05010	COG0673	inositol 2-dehydrogenase activity
LDP77_05015	COG0450	alkyl hydroperoxide reductase
LDP77_05020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDP77_05055	COG4251	negative regulation of phosphorylation
LDP77_05055	COG5001	Diguanylate cyclase
LDP77_05055	COG3706	GGDEF domain
LDP77_05055	COG2203	Gaf domain
LDP77_05060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDP77_05150	COG1649	PFAM Uncharacterised BCR, COG1649
LDP77_05155	COG1737	Transcriptional regulator
LDP77_05175	COG1486	melibiose metabolic process
LDP77_05185	COG1447	Phosphotransferase system cellobiose-specific component IIA
LDP77_05195	COG2971	BadF BadG BcrA BcrD
LDP77_05200	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LDP77_05205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP77_05215	COG3037	sugar-specific permease SgaT UlaA
LDP77_05220	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LDP77_05220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDP77_05230	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LDP77_05255	COG4106	trans-aconitate 2-methyltransferase activity
LDP77_05260	COG0583	DNA-binding transcription factor activity
LDP77_05270	COG0667	Aldo Keto reductase
LDP77_05285	COG0154	amidase activity
LDP77_05295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LDP77_05335	COG2200	EAL domain
LDP77_05335	COG2199	diguanylate cyclase activity
LDP77_05345	COG1733	regulation of RNA biosynthetic process
LDP77_05360	COG0385	Bile acid
LDP77_05370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDP77_05375	COG4191	Histidine kinase
LDP77_05380	COG0784	Response regulator, receiver
LDP77_05395	COG1388	LysM domain
LDP77_05395	COG0791	NLP P60 protein
LDP77_05405	COG2385	sporulation resulting in formation of a cellular spore
LDP77_05410	COG0656	L-ascorbic acid biosynthetic process
LDP77_05430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LDP77_05435	COG4948	Mandelate Racemase Muconate Lactonizing
LDP77_05455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LDP77_05470	COG0477	Major facilitator Superfamily
LDP77_05475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDP77_05480	COG0640	Transcriptional regulator
LDP77_05485	COG5658	integral membrane protein
LDP77_05505	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LDP77_05525	COG1132	(ABC) transporter
LDP77_05535	COG3300	MHYT domain
LDP77_05535	COG5001	Diguanylate cyclase
LDP77_05540	COG0302	gtp cyclohydrolase
LDP77_05580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDP77_05615	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LDP77_05635	COG1396	sequence-specific DNA binding
LDP77_05640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDP77_05650	COG0297	glycogen (starch) synthase activity
LDP77_05650	COG0438	transferase activity, transferring glycosyl groups
LDP77_05660	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LDP77_05665	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LDP77_05670	COG0438	transferase activity, transferring glycosyl groups
LDP77_05675	COG2244	polysaccharide biosynthetic process
LDP77_05685	COG1482	cell wall glycoprotein biosynthetic process
LDP77_05690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDP77_05695	COG3944	biosynthesis protein
LDP77_05700	COG0489	protein tyrosine kinase activity
LDP77_05705	COG4464	protein tyrosine phosphatase activity
LDP77_05710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LDP77_05715	COG1316	TRANSCRIPTIONal
LDP77_05725	COG4464	protein tyrosine phosphatase activity
LDP77_05735	COG0028	Belongs to the TPP enzyme family
LDP77_05740	COG0069	glutamate synthase activity
LDP77_05750	COG2084	Dehydrogenase
LDP77_05790	COG4124	Belongs to the glycosyl hydrolase 26 family
LDP77_05815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDP77_05820	COG2146	nitrite reductase [NAD(P)H] activity
LDP77_05830	COG2116	formate transmembrane transporter activity
LDP77_05840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDP77_05845	COG4975	Glucose uptake
LDP77_05865	COG0534	Mate efflux family protein
LDP77_05875	COG1316	TRANSCRIPTIONal
LDP77_05885	COG0598	Magnesium transport protein CorA
LDP77_05890	COG1404	Belongs to the peptidase S8 family
LDP77_05910	COG4821	SIS domain
LDP77_05915	COG2188	Transcriptional regulator
LDP77_05920	COG0363	glucosamine-6-phosphate deaminase activity
LDP77_05925	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDP77_05930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP77_05930	COG2190	(PTS) system
LDP77_05930	COG1263	PTS System
LDP77_05935	COG1811	Na channel or pump
LDP77_05940	COG3961	Belongs to the TPP enzyme family
LDP77_05975	COG1131	(ABC) transporter
LDP77_05980	COG1253	flavin adenine dinucleotide binding
LDP77_05985	COG0789	Transcriptional regulator
LDP77_05995	COG0346	lactoylglutathione lyase activity
LDP77_06000	COG2105	PFAM AIG2 family protein
LDP77_06000	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LDP77_06045	COG0456	acetyltransferase
LDP77_06050	COG1473	amidohydrolase
LDP77_06060	COG4187	Peptidase family M20/M25/M40
LDP77_06075	COG0456	acetyltransferase
LDP77_06075	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LDP77_06095	COG2252	PERMEase
LDP77_06105	COG3279	Response regulator of the LytR AlgR family
LDP77_06110	COG4555	ABC transporter
LDP77_06115	COG1668	transmembrane transport
LDP77_06125	COG0789	Transcriptional regulator
LDP77_06130	COG1846	Transcriptional regulator
LDP77_06140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDP77_06160	COG1785	Belongs to the alkaline phosphatase family
LDP77_06165	COG3279	Response regulator of the LytR AlgR family
LDP77_06170	COG0784	Response regulator, receiver
LDP77_06170	COG2205	protein histidine kinase activity
LDP77_06175	COG0861	Integral membrane protein TerC family
LDP77_06180	COG1191	sigma factor activity
LDP77_06210	COG3243	poly(R)-hydroxyalkanoic acid synthase
LDP77_06215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDP77_06235	COG2186	Transcriptional regulator
LDP77_06240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LDP77_06250	COG0247	lactate metabolic process
LDP77_06255	COG1139	Iron-sulfur cluster binding protein
LDP77_06260	COG1556	Lactate utilization protein
LDP77_06265	COG5002	protein histidine kinase activity
LDP77_06270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LDP77_06280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LDP77_06285	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LDP77_06290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDP77_06295	COG0436	Aminotransferase
LDP77_06300	COG1850	ribulose-bisphosphate carboxylase activity
LDP77_06305	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LDP77_06310	COG0235	Class ii aldolase
LDP77_06315	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LDP77_06325	COG1129	ABC transporter
LDP77_06330	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDP77_06355	COG1846	Transcriptional regulator
LDP77_06365	COG4191	Histidine kinase
LDP77_06375	COG0542	response to heat
LDP77_06380	COG1757	Na H antiporter
LDP77_06395	COG0300	oxidoreductase activity
LDP77_06400	COG0697	spore germination
LDP77_06420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LDP77_06425	COG0720	synthase
LDP77_06435	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LDP77_06440	COG0702	epimerase
LDP77_06450	COG4873	Protein conserved in bacteria
LDP77_06470	COG3773	Cell wall hydrolase
LDP77_06510	COG0646	methionine synthase
LDP77_06510	COG1410	methionine synthase
LDP77_06515	COG0646	methionine synthase
LDP77_06515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LDP77_06520	COG3949	Membrane
LDP77_06525	COG0307	riboflavin synthase, alpha
LDP77_06535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LDP77_06545	COG3711	transcriptional antiterminator
LDP77_06550	COG1263	PTS System
LDP77_06550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP77_06550	COG2190	(PTS) system
LDP77_06565	COG1346	cytolysis
LDP77_06575	COG0583	DNA-binding transcription factor activity
LDP77_06585	COG0456	acetyltransferase
LDP77_06590	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_06595	COG0778	Nitroreductase
LDP77_06600	COG0436	Aminotransferase
LDP77_06620	COG0784	Response regulator, receiver
LDP77_06620	COG0835	chemotaxis
LDP77_06630	COG1376	ErfK ybiS ycfS ynhG family protein
LDP77_06650	COG1408	metallophosphoesterase
LDP77_06655	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_06660	COG2200	EAL domain
LDP77_06675	COG4703	Protein of unknown function (DUF1797)
LDP77_06680	COG0517	IMP dehydrogenase activity
LDP77_06685	COG0583	DNA-binding transcription factor activity
LDP77_06690	COG2171	N-acyltransferase activity
LDP77_06695	COG1473	amidohydrolase
LDP77_06705	COG0668	transmembrane transport
LDP77_06710	COG0450	alkyl hydroperoxide reductase
LDP77_06715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDP77_06720	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LDP77_06725	COG1132	(ABC) transporter
LDP77_06730	COG1132	(ABC) transporter
LDP77_06735	COG0569	domain protein
LDP77_06740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LDP77_06745	COG5503	Protein of unknown function (DUF1447)
LDP77_06750	COG0561	phosphatase activity
LDP77_06775	COG0022	dehydrogenase e1 component
LDP77_06780	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDP77_06805	COG1982	Orn Lys Arg decarboxylase major
LDP77_06810	COG4476	Belongs to the UPF0223 family
LDP77_06815	COG4493	Belongs to the UPF0637 family
LDP77_06825	COG0483	inositol monophosphate 1-phosphatase activity
LDP77_06835	COG1217	gtp-binding protein TYPA
LDP77_06850	COG4896	Protein conserved in bacteria
LDP77_06865	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LDP77_06870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LDP77_06875	COG4838	Belongs to the UPF0358 family
LDP77_06880	COG0772	Belongs to the SEDS family
LDP77_06885	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LDP77_06890	COG1612	heme a metabolic process
LDP77_06895	COG0109	protoheme IX farnesyltransferase activity
LDP77_06920	COG3336	cytochrome c oxidase
LDP77_06930	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LDP77_06935	COG2340	Cysteine-rich secretory protein family
LDP77_06945	COG2738	Putative neutral zinc metallopeptidase
LDP77_06950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_06955	COG1694	Mazg nucleotide pyrophosphohydrolase
LDP77_06960	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LDP77_06965	COG1803	Methylglyoxal synthase
LDP77_06970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LDP77_06975	COG0438	transferase activity, transferring glycosyl groups
LDP77_06980	COG0617	tRNA 3'-terminal CCA addition
LDP77_06985	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LDP77_06985	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LDP77_06995	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LDP77_07000	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LDP77_07005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LDP77_07005	COG1199	ATP-dependent helicase activity
LDP77_07025	COG0436	Aminotransferase
LDP77_07030	COG0017	Asparaginyl-tRNA synthetase
LDP77_07035	COG3935	DnaD domain protein
LDP77_07040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LDP77_07050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDP77_07050	COG4499	WXG100 protein secretion system (Wss), protein YukC
LDP77_07055	COG3331	DNA recombination
LDP77_07100	COG5337	Spore coat protein CotH
LDP77_07115	COG0626	cystathionine gamma-synthase activity
LDP77_07120	COG0626	cystathionine gamma-synthase activity
LDP77_07135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDP77_07160	COG3706	GGDEF domain
LDP77_07170	COG1111	helicase
LDP77_07170	COG1205	dead DEAH box helicase
LDP77_07175	COG3359	exonuclease
LDP77_07185	COG4474	Belongs to the UPF0398 family
LDP77_07190	COG3599	regulation of cell shape
LDP77_07220	COG2197	response regulator
LDP77_07225	COG0366	Alpha amylase catalytic
LDP77_07230	COG0116	Belongs to the methyltransferase superfamily
LDP77_07245	COG1175	transmembrane transport
LDP77_07255	COG3842	ATPase activity
LDP77_07265	COG1199	ATP-dependent helicase activity
LDP77_07270	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LDP77_07275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDP77_07280	COG2233	PERMEase
LDP77_07285	COG0583	DNA-binding transcription factor activity
LDP77_07290	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_07300	COG3424	synthase
LDP77_07305	COG1755	Isoprenylcysteine carboxyl methyltransferase
LDP77_07310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LDP77_07315	COG3541	Predicted nucleotidyltransferase
LDP77_07340	COG0328	RNA-DNA hybrid ribonuclease activity
LDP77_07345	COG0328	RNA-DNA hybrid ribonuclease activity
LDP77_07370	COG2814	Major facilitator Superfamily
LDP77_07380	COG2233	PERMEase
LDP77_07385	COG2362	D-Aminopeptidase
LDP77_07390	COG0601	transmembrane transport
LDP77_07395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDP77_07400	COG0444	Belongs to the ABC transporter superfamily
LDP77_07405	COG4166	transmembrane transport
LDP77_07410	COG1619	proteins homologs of microcin C7 resistance protein MccF
LDP77_07415	COG0791	NLP P60 protein
LDP77_07420	COG4608	Belongs to the ABC transporter superfamily
LDP77_07440	COG3300	MHYT domain
LDP77_07440	COG5001	Diguanylate cyclase
LDP77_07465	COG2197	response regulator
LDP77_07470	COG4585	Histidine kinase
LDP77_07475	COG3239	Fatty acid desaturase
LDP77_07480	COG2205	protein histidine kinase activity
LDP77_07490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDP77_07505	COG0791	NLP P60 protein
LDP77_07505	COG1388	LysM domain
LDP77_07510	COG1819	glycosyl
LDP77_07515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LDP77_07530	COG2814	Major facilitator Superfamily
LDP77_07540	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_07545	COG3964	amidohydrolase
LDP77_07565	COG2188	Transcriptional regulator
LDP77_07575	COG0434	BtpA family
LDP77_07580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDP77_07590	COG1785	Belongs to the alkaline phosphatase family
LDP77_07595	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LDP77_07600	COG1404	Belongs to the peptidase S8 family
LDP77_07610	COG1846	Transcriptional regulator
LDP77_07615	COG1566	PFAM secretion protein HlyD family protein
LDP77_07620	COG2814	Major facilitator Superfamily
LDP77_07625	COG1846	Transcriptional regulator
LDP77_07645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP77_07650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP77_07655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDP77_07660	COG1120	ATPase activity
LDP77_07665	COG0492	ferredoxin-NADP+ reductase activity
LDP77_07675	COG2814	Major facilitator Superfamily
LDP77_07695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LDP77_07700	COG1733	regulation of RNA biosynthetic process
LDP77_07705	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LDP77_07715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDP77_07725	COG4175	Glycine betaine
LDP77_07725	COG3448	diguanylate cyclase activity
LDP77_07730	COG4176	ABC-type proline glycine betaine transport system permease component
LDP77_07740	COG0784	Response regulator, receiver
LDP77_07740	COG2205	protein histidine kinase activity
LDP77_07745	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LDP77_07750	COG2208	phosphoserine phosphatase activity
LDP77_07760	COG0531	amino acid
LDP77_07770	COG1011	Hydrolase
LDP77_07775	COG0405	Gamma-glutamyltransferase
LDP77_07780	COG1621	beta-fructofuranosidase activity
LDP77_07785	COG1621	beta-fructofuranosidase activity
LDP77_07790	COG2193	ferroxidase activity
LDP77_07795	COG0477	Major facilitator Superfamily
LDP77_07800	COG0156	8-amino-7-oxononanoate synthase activity
LDP77_07805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDP77_07815	COG2814	Major facilitator Superfamily
LDP77_07830	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_07835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP77_07845	COG1280	lysine exporter protein (LysE YggA)
LDP77_07850	COG1113	amino acid transport
LDP77_07865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LDP77_07900	COG1113	amino acid transport
LDP77_07920	COG1609	Transcriptional regulator
LDP77_07935	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LDP77_07940	COG1621	beta-fructofuranosidase activity
LDP77_07945	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LDP77_07945	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LDP77_07950	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP77_07955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP77_07960	COG3715	PTS system
LDP77_07965	COG3716	PTS system mannose fructose sorbose family IID component
LDP77_07970	COG1621	beta-fructofuranosidase activity
LDP77_07975	COG0765	amino acid transport
LDP77_07980	COG0765	amino acid transport
LDP77_07985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP77_07990	COG1464	Belongs to the NlpA lipoprotein family
LDP77_07995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LDP77_08000	COG2011	ABC-type metal ion transport system permease component
LDP77_08020	COG1464	Belongs to the NlpA lipoprotein family
LDP77_08025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LDP77_08030	COG2011	ABC-type metal ion transport system permease component
LDP77_08035	COG1464	Belongs to the NlpA lipoprotein family
LDP77_08040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_08065	COG0596	Alpha beta hydrolase
LDP77_08070	COG0697	spore germination
LDP77_08085	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LDP77_08090	COG0531	amino acid
LDP77_08105	COG2723	6-phospho-beta-galactosidase activity
LDP77_08110	COG2188	Transcriptional regulator
LDP77_08120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LDP77_08130	COG0656	L-ascorbic acid biosynthetic process
LDP77_08135	COG2986	histidine ammonia-lyase
LDP77_08145	COG1228	amidohydrolase
LDP77_08150	COG0010	Belongs to the arginase family
LDP77_08155	COG1846	Transcriptional regulator
LDP77_08175	COG1288	antiporter activity
LDP77_08180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDP77_08220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_08240	COG2364	Membrane
LDP77_08245	COG1846	Transcriptional regulator
LDP77_08250	COG0456	acetyltransferase
LDP77_08285	COG0574	Belongs to the PEP-utilizing enzyme family
LDP77_08285	COG3848	Pyruvate phosphate dikinase
LDP77_08290	COG1309	transcriptional regulator
LDP77_08295	COG2814	Major facilitator Superfamily
LDP77_08300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LDP77_08305	COG3958	Transketolase
LDP77_08310	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_08315	COG2186	Transcriptional regulator
LDP77_08325	COG0205	6-phosphofructokinase activity
LDP77_08335	COG0698	ribose 5-phosphate isomerase
LDP77_08360	COG0791	NLP P60 protein
LDP77_08360	COG1388	LysM domain
LDP77_08365	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LDP77_08380	COG2318	DinB family
LDP77_08400	COG0583	DNA-binding transcription factor activity
LDP77_08405	COG0596	Alpha beta hydrolase
LDP77_08435	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_08455	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LDP77_08465	COG0697	spore germination
LDP77_08495	COG0387	Pfam Sodium calcium exchanger
LDP77_08500	COG0318	PFAM AMP-dependent synthetase and ligase
LDP77_08515	COG1309	transcriptional regulator
LDP77_08520	COG0861	Integral membrane protein TerC family
LDP77_08530	COG5577	PFAM Coat F domain
LDP77_08540	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_08550	COG1522	sequence-specific DNA binding
LDP77_08555	COG3813	Protein conserved in bacteria
LDP77_08580	COG2076	Multidrug Resistance protein
LDP77_08595	COG1278	Cold shock
LDP77_08605	COG0513	Belongs to the DEAD box helicase family
LDP77_08610	COG1278	Cold shock
LDP77_08625	COG0028	Belongs to the TPP enzyme family
LDP77_08665	COG0747	negative chemotaxis
LDP77_08670	COG0601	transmembrane transport
LDP77_08675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDP77_08680	COG0444	Belongs to the ABC transporter superfamily
LDP77_08685	COG4608	Belongs to the ABC transporter superfamily
LDP77_08690	COG0534	Mate efflux family protein
LDP77_08710	COG2172	sigma factor antagonist activity
LDP77_08720	COG0477	Major facilitator Superfamily
LDP77_08725	COG1388	LysM domain
LDP77_08725	COG3858	chitin binding
LDP77_08730	COG1376	ErfK ybiS ycfS ynhG family protein
LDP77_08735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDP77_08760	COG2226	methyltransferase
LDP77_08770	COG1733	regulation of RNA biosynthetic process
LDP77_08775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP77_08795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_08800	COG3420	alginic acid biosynthetic process
LDP77_08820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LDP77_08825	COG0640	Transcriptional regulator
LDP77_08830	COG0640	Transcriptional regulator
LDP77_08840	COG0589	response to stress
LDP77_08840	COG0475	glutathione-regulated potassium exporter activity
LDP77_08850	COG3011	Protein conserved in bacteria
LDP77_08880	COG0583	DNA-binding transcription factor activity
LDP77_08885	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LDP77_08900	COG0753	catalase activity
LDP77_08915	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_08920	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_08940	COG0384	phenazine biosynthesis protein PhzF
LDP77_08950	COG5577	PFAM Coat F domain
LDP77_08960	COG1063	alcohol dehydrogenase
LDP77_08965	COG5577	PFAM Coat F domain
LDP77_08980	COG2205	protein histidine kinase activity
LDP77_08980	COG0784	Response regulator, receiver
LDP77_09000	COG0673	inositol 2-dehydrogenase activity
LDP77_09005	COG0673	inositol 2-dehydrogenase activity
LDP77_09010	COG1082	Xylose isomerase domain protein TIM barrel
LDP77_09015	COG2814	Major facilitator Superfamily
LDP77_09025	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_09040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_09055	COG0384	phenazine biosynthesis protein PhzF
LDP77_09060	COG1694	Mazg nucleotide pyrophosphohydrolase
LDP77_09070	COG2226	methyltransferase
LDP77_09085	COG1278	Cold shock
LDP77_09145	COG1113	amino acid transport
LDP77_09155	COG2207	Transcriptional regulator
LDP77_09165	COG2376	Dihydroxyacetone kinase
LDP77_09205	COG1073	alpha beta
LDP77_09220	COG3545	Serine hydrolase
LDP77_09225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDP77_09235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LDP77_09250	COG1278	Cold shock
LDP77_09260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP77_09265	COG0697	spore germination
LDP77_09280	COG2226	methyltransferase
LDP77_09290	COG1335	isochorismatase
LDP77_09295	COG0138	bifunctional purine biosynthesis protein purh
LDP77_09300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_09305	COG1114	Component of the transport system for branched-chain amino acids
LDP77_09315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LDP77_09325	COG4282	regulation of fungal-type cell wall biogenesis
LDP77_09350	COG0574	Belongs to the PEP-utilizing enzyme family
LDP77_09350	COG3848	Pyruvate phosphate dikinase
LDP77_09355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LDP77_09365	COG0601	transmembrane transport
LDP77_09370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDP77_09375	COG0444	Belongs to the ABC transporter superfamily
LDP77_09380	COG4608	Belongs to the ABC transporter superfamily
LDP77_09385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LDP77_09395	COG0477	Major facilitator Superfamily
LDP77_09415	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_09450	COG0517	IMP dehydrogenase activity
LDP77_09470	COG1309	transcriptional regulator
LDP77_09485	COG1070	Carbohydrate kinase
LDP77_09490	COG0477	Major facilitator Superfamily
LDP77_09490	COG2814	Major facilitator Superfamily
LDP77_09500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDP77_09505	COG1845	cytochrome c oxidase, subunit III
LDP77_09515	COG0589	response to stress
LDP77_09520	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_09525	COG1612	heme a metabolic process
LDP77_09530	COG2072	flavoprotein involved in K transport
LDP77_09540	COG2252	PERMEase
LDP77_09550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LDP77_09555	COG0022	dehydrogenase e1 component
LDP77_09560	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDP77_09565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDP77_09570	COG3284	Transcriptional regulator
LDP77_09575	COG1063	alcohol dehydrogenase
LDP77_09590	COG1846	Transcriptional regulator
LDP77_09600	COG2721	sulfolactate sulfo-lyase activity
LDP77_09610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDP77_09615	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_09620	COG2271	Major facilitator Superfamily
LDP77_09625	COG4948	Mandelate Racemase Muconate Lactonizing
LDP77_09630	COG2186	Transcriptional regulator
LDP77_09650	COG0628	permease
LDP77_09655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDP77_09660	COG1904	glucuronate isomerase
LDP77_09665	COG2211	Major facilitator Superfamily
LDP77_09670	COG1609	Transcriptional regulator
LDP77_09675	COG0246	Mannitol dehydrogenase
LDP77_09680	COG2721	sulfolactate sulfo-lyase activity
LDP77_09695	COG2211	Major facilitator Superfamily
LDP77_09715	COG0589	response to stress
LDP77_09720	COG5002	protein histidine kinase activity
LDP77_09730	COG1937	Protein conserved in bacteria
LDP77_09735	COG2608	mercury ion transmembrane transporter activity
LDP77_09740	COG2217	Heavy metal translocating P-type atpase
LDP77_09750	COG1388	LysM domain
LDP77_09755	COG2271	Major facilitator Superfamily
LDP77_09785	COG0640	Transcriptional regulator
LDP77_09790	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LDP77_09795	COG0551	DNA topoisomerase type I activity
LDP77_09795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDP77_09800	COG5444	nuclease activity
LDP77_09825	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LDP77_09830	COG2323	membrane
LDP77_09845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LDP77_09850	COG1802	Transcriptional regulator
LDP77_09855	COG0473	3-isopropylmalate dehydrogenase activity
LDP77_09860	COG2814	Major facilitator Superfamily
LDP77_09865	COG1733	regulation of RNA biosynthetic process
LDP77_09870	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDP77_09870	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDP77_09875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LDP77_09875	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LDP77_09905	COG5566	PFAM Mor transcription activator
LDP77_09920	COG0561	phosphatase activity
LDP77_09925	COG1876	peptidase activity
LDP77_09975	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LDP77_09990	COG0386	Belongs to the glutathione peroxidase family
LDP77_09995	COG1418	mRNA catabolic process
LDP77_10000	COG0488	(ABC) transporter
LDP77_10005	COG1413	lyase activity
LDP77_10020	COG2136	Putative SAM-dependent methyltransferase
LDP77_10020	COG2521	methyltransferase
LDP77_10030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDP77_10035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDP77_10045	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LDP77_10050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDP77_10060	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LDP77_10065	COG0406	alpha-ribazole phosphatase activity
LDP77_10075	COG2096	Adenosyltransferase
LDP77_10080	COG2962	Rard protein
LDP77_10095	COG0523	cobalamin synthesis protein
LDP77_10100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LDP77_10105	COG0322	excinuclease ABC activity
LDP77_10115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDP77_10120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LDP77_10125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LDP77_10130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDP77_10135	COG3011	Protein conserved in bacteria
LDP77_10140	COG1595	DNA-templated transcription, initiation
LDP77_10160	COG2002	toxin-antitoxin pair type II binding
LDP77_10165	COG0534	Mate efflux family protein
LDP77_10170	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_10195	COG1368	sulfuric ester hydrolase activity
LDP77_10205	COG3853	Toxic anion resistance protein (TelA)
LDP77_10235	COG2234	aminopeptidase activity
LDP77_10240	COG5002	protein histidine kinase activity
LDP77_10250	COG1823	symporter activity
LDP77_10255	COG1523	belongs to the glycosyl hydrolase 13 family
LDP77_10260	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_10265	COG2124	cytochrome p450
LDP77_10270	COG2112	serine threonine protein kinase
LDP77_10285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LDP77_10290	COG1360	Flagellar Motor Protein
LDP77_10305	COG3361	conserved protein (COG2071)
LDP77_10310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDP77_10315	COG1757	Na H antiporter
LDP77_10325	COG0833	amino acid
LDP77_10330	COG3594	Acyltransferase
LDP77_10335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDP77_10340	COG0745	RESPONSE REGULATOR receiver
LDP77_10345	COG5002	protein histidine kinase activity
LDP77_10350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDP77_10355	COG3104	oligopeptide transport
LDP77_10365	COG0281	malic enzyme
LDP77_10370	COG3493	citrate carrier protein
LDP77_10375	COG0561	phosphatase activity
LDP77_10380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_10390	COG0456	acetyltransferase
LDP77_10395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LDP77_10400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP77_10405	COG0765	amino acid transport
LDP77_10410	COG0765	amino acid transport
LDP77_10415	COG1126	abc transporter atp-binding protein
LDP77_10420	COG0196	riboflavin kinase activity
LDP77_10425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_10435	COG0860	N-Acetylmuramoyl-L-alanine amidase
LDP77_10475	COG1611	Belongs to the LOG family
LDP77_10480	COG0281	malic enzyme
LDP77_10485	COG3402	PFAM membrane-flanked domain
LDP77_10490	COG3428	Bacterial PH domain
LDP77_10505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDP77_10510	COG0109	protoheme IX farnesyltransferase activity
LDP77_10515	COG4195	phage-related replication protein
LDP77_10530	COG0789	Transcriptional regulator
LDP77_10565	COG0583	DNA-binding transcription factor activity
LDP77_10570	COG0069	glutamate synthase activity
LDP77_10570	COG0070	glutamate synthase
LDP77_10570	COG0067	glutamate synthase
LDP77_10575	COG0493	'glutamate synthase
LDP77_10595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDP77_10610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDP77_10625	COG1846	Transcriptional regulator
LDP77_10630	COG1380	Effector of murein hydrolase LrgA
LDP77_10635	COG1346	cytolysis
LDP77_10640	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_10660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LDP77_10665	COG0463	Glycosyl transferase, family 2
LDP77_10675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LDP77_10680	COG0745	RESPONSE REGULATOR receiver
LDP77_10690	COG5583	Uncharacterized small protein (DUF2292)
LDP77_10700	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LDP77_10710	COG4208	sulfate ABC transporter
LDP77_10725	COG0745	RESPONSE REGULATOR receiver
LDP77_10750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_10765	COG1349	DNA-binding transcription factor activity
LDP77_10770	COG1105	Belongs to the carbohydrate kinase PfkB family
LDP77_10775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDP77_10775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDP77_10775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP77_10780	COG0527	aspartate kinase activity
LDP77_10790	COG2032	superoxide dismutase activity
LDP77_10795	COG1233	COG1233 Phytoene dehydrogenase and related
LDP77_10805	COG0300	oxidoreductase activity
LDP77_10810	COG0640	Transcriptional regulator
LDP77_10815	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_10820	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LDP77_10835	COG0733	neurotransmitter:sodium symporter activity
LDP77_10845	COG3773	Cell wall hydrolase
LDP77_10865	COG0673	inositol 2-dehydrogenase activity
LDP77_10870	COG1082	Xylose isomerase domain protein TIM barrel
LDP77_10875	COG2094	Belongs to the DNA glycosylase MPG family
LDP77_10880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LDP77_10890	COG0454	-acetyltransferase
LDP77_10900	COG2814	Major facilitator Superfamily
LDP77_10915	COG3871	stress protein (general stress protein 26)
LDP77_10940	COG1595	DNA-templated transcription, initiation
LDP77_10945	COG4873	Protein conserved in bacteria
LDP77_10950	COG0714	Associated with various cellular activities
LDP77_10955	COG4548	von Willebrand factor, type A
LDP77_10960	COG0697	spore germination
LDP77_10970	COG2207	Transcriptional regulator
LDP77_10975	COG1994	Peptidase M50
LDP77_10980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_10985	COG1119	ATPase activity
LDP77_11000	COG1657	PFAM Prenyltransferase squalene oxidase
LDP77_11010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LDP77_11010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LDP77_11020	COG0384	phenazine biosynthesis protein PhzF
LDP77_11035	COG1378	Sugar-specific transcriptional regulator TrmB
LDP77_11040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LDP77_11045	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_11065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP77_11070	COG1279	arginine transmembrane transporter activity
LDP77_11100	COG1396	sequence-specific DNA binding
LDP77_11115	COG0494	nUDIX hydrolase
LDP77_11120	COG1335	isochorismatase
LDP77_11125	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LDP77_11130	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LDP77_11135	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LDP77_11140	COG1098	S1 RNA binding domain
LDP77_11150	COG1404	Belongs to the peptidase S8 family
LDP77_11155	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_11160	COG1254	Belongs to the acylphosphatase family
LDP77_11165	COG2223	nitrite transmembrane transporter activity
LDP77_11170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_11180	COG2207	Transcriptional regulator
LDP77_11180	COG0662	Cupin 2, conserved barrel domain protein
LDP77_11185	COG0697	spore germination
LDP77_11190	COG0488	(ABC) transporter
LDP77_11195	COG0697	spore germination
LDP77_11200	COG0531	amino acid
LDP77_11215	COG1131	(ABC) transporter
LDP77_11220	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LDP77_11225	COG1757	Na H antiporter
LDP77_11230	COG1609	Transcriptional regulator
LDP77_11240	COG1533	DNA photolyase activity
LDP77_11260	COG0551	DNA topoisomerase type I activity
LDP77_11260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDP77_11270	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDP77_11295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDP77_11315	COG1757	Na H antiporter
LDP77_11320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LDP77_11330	COG0697	spore germination
LDP77_11340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_11350	COG2720	vancomycin resistance protein
LDP77_11390	COG0514	ATP-dependent DNA helicase (RecQ)
LDP77_11405	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_11420	COG1575	Belongs to the MenA family. Type 1 subfamily
LDP77_11425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LDP77_11440	COG2814	Major facilitator Superfamily
LDP77_11445	COG0583	DNA-binding transcription factor activity
LDP77_11450	COG1725	Transcriptional regulator
LDP77_11455	COG1131	(ABC) transporter
LDP77_11465	COG1595	DNA-templated transcription, initiation
LDP77_11480	COG1764	response to oxidative stress
LDP77_11485	COG1846	Transcriptional regulator
LDP77_11500	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
LDP77_11510	COG1388	LysM domain
LDP77_11510	COG3584	3D domain protein
LDP77_11530	COG5002	protein histidine kinase activity
LDP77_11535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDP77_11540	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LDP77_11545	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LDP77_11560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDP77_11575	COG2409	Drug exporters of the RND superfamily
LDP77_11580	COG1834	amidinotransferase
LDP77_11590	COG1295	ribonuclease BN
LDP77_11670	COG0110	maltose O-acetyltransferase activity
LDP77_11675	COG0346	lactoylglutathione lyase activity
LDP77_11685	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_11695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDP77_11705	COG2176	DNA-directed DNA polymerase activity
LDP77_11720	COG0114	fumarate hydratase activity
LDP77_11730	COG3409	Peptidoglycan-binding domain 1 protein
LDP77_11730	COG3757	hydrolase, family 25
LDP77_11740	COG5002	protein histidine kinase activity
LDP77_11775	COG0778	Nitroreductase
LDP77_11785	COG0300	oxidoreductase activity
LDP77_11795	COG2610	gluconate transmembrane transporter activity
LDP77_11800	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_11805	COG2195	Cleaves the N-terminal amino acid of tripeptides
LDP77_11830	COG4122	O-methyltransferase activity
LDP77_11835	COG0583	DNA-binding transcription factor activity
LDP77_11845	COG1301	dicarboxylic acid transport
LDP77_11850	COG0019	diaminopimelate decarboxylase activity
LDP77_11860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDP77_11870	COG4191	Histidine kinase
LDP77_11885	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_11890	COG0318	PFAM AMP-dependent synthetase and ligase
LDP77_11900	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDP77_11905	COG1024	Enoyl-CoA hydratase
LDP77_11920	COG2045	Belongs to the ComB family
LDP77_11925	COG1960	acyl-CoA dehydrogenase activity
LDP77_11930	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_11935	COG1024	Enoyl-CoA hydratase
LDP77_11950	COG1141	Ferredoxin
LDP77_11960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LDP77_11970	COG0183	Belongs to the thiolase family
LDP77_11975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDP77_11980	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LDP77_12000	COG1509	lysine 2,3-aminomutase activity
LDP77_12010	COG0833	amino acid
LDP77_12015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP77_12030	COG1979	alcohol dehydrogenase
LDP77_12035	COG0738	Major facilitator superfamily
LDP77_12040	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDP77_12060	COG3977	Valine--pyruvate aminotransferase
LDP77_12065	COG3773	Cell wall hydrolase
LDP77_12075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LDP77_12085	COG0531	amino acid
LDP77_12090	COG2814	Major facilitator Superfamily
LDP77_12095	COG1846	Transcriptional regulator
LDP77_12100	COG2409	Drug exporters of the RND superfamily
LDP77_12100	COG1033	growth of symbiont in host cell
LDP77_12115	COG3842	ATPase activity
LDP77_12120	COG2222	sugar isomerase
LDP77_12125	COG1653	transport
LDP77_12130	COG1175	transmembrane transport
LDP77_12135	COG0395	ABC-type sugar transport system, permease component
LDP77_12140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDP77_12145	COG2188	Transcriptional regulator
LDP77_12150	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_12150	COG2202	Pas domain
LDP77_12155	COG3832	glyoxalase III activity
LDP77_12160	COG0640	Transcriptional regulator
LDP77_12170	COG2267	carboxylic ester hydrolase activity
LDP77_12180	COG3386	PFAM SMP-30 Gluconolaconase
LDP77_12190	COG2368	4-hydroxyphenylacetate
LDP77_12195	COG3739	integral membrane protein
LDP77_12205	COG0326	Molecular chaperone. Has ATPase activity
LDP77_12210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDP77_12235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDP77_12240	COG3757	hydrolase, family 25
LDP77_12240	COG3409	Peptidoglycan-binding domain 1 protein
LDP77_12250	COG0697	spore germination
LDP77_12255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP77_12270	COG4572	Cation transport regulator
LDP77_12275	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LDP77_12285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LDP77_12300	COG3011	Protein conserved in bacteria
LDP77_12305	COG1136	(ABC) transporter
LDP77_12360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDP77_12375	COG0494	nUDIX hydrolase
LDP77_12380	COG0702	epimerase
LDP77_12385	COG0318	PFAM AMP-dependent synthetase and ligase
LDP77_12390	COG1846	Transcriptional regulator
LDP77_12395	COG2720	vancomycin resistance protein
LDP77_12400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDP77_12425	COG0076	glutamate decarboxylase activity
LDP77_12450	COG2116	formate transmembrane transporter activity
LDP77_12455	COG5609	conserved protein (DUF2294)
LDP77_12470	COG2271	Major facilitator Superfamily
LDP77_12475	COG0277	FAD linked oxidase domain protein
LDP77_12485	COG0840	transmembrane signaling receptor activity
LDP77_12495	COG0622	Phosphoesterase
LDP77_12505	COG1408	metallophosphoesterase
LDP77_12510	COG3663	DNA glycosylase
LDP77_12515	COG3883	PFAM NLP P60 protein
LDP77_12515	COG0791	NLP P60 protein
LDP77_12520	COG1587	Uroporphyrinogen-III synthase
LDP77_12525	COG1414	Transcriptional regulator
LDP77_12530	COG0439	Biotin carboxylase
LDP77_12535	COG0511	ligase activity, forming carbon-carbon bonds
LDP77_12540	COG1984	allophanate hydrolase subunit 2
LDP77_12545	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LDP77_12550	COG4336	lyase activity
LDP77_12555	COG1914	H( )-stimulated, divalent metal cation uptake system
LDP77_12560	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LDP77_12575	COG0318	PFAM AMP-dependent synthetase and ligase
LDP77_12580	COG1268	BioY protein
LDP77_12585	COG0183	Belongs to the thiolase family
LDP77_12605	COG0431	NADPH-dependent FMN reductase
LDP77_12610	COG2197	response regulator
LDP77_12615	COG4585	Histidine kinase
LDP77_12615	COG2203	Gaf domain
LDP77_12635	COG0697	spore germination
LDP77_12645	COG2153	protein acetylation
LDP77_12650	COG0129	dihydroxy-acid dehydratase activity
LDP77_12655	COG2267	carboxylic ester hydrolase activity
LDP77_12660	COG1227	inorganic diphosphatase activity
LDP77_12680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDP77_12690	COG0204	Acyl-transferase
LDP77_12695	COG2233	PERMEase
LDP77_12700	COG3195	allantoin biosynthetic process
LDP77_12700	COG3648	Uricase
LDP77_12725	COG1914	H( )-stimulated, divalent metal cation uptake system
LDP77_12740	COG1011	Hydrolase
LDP77_12745	COG1846	Transcriptional regulator
LDP77_12755	COG4974	Belongs to the 'phage' integrase family
LDP77_12775	COG0531	amino acid
LDP77_12780	COG4302	ethanolamine ammonia-lyase activity
LDP77_12785	COG4303	Ethanolamine ammonia lyase large subunit
LDP77_12790	COG4819	ethanolamine utilization protein
LDP77_12800	COG0833	amino acid
LDP77_12810	COG1247	-acetyltransferase
LDP77_12815	COG1335	isochorismatase
LDP77_12825	COG3403	YqcI/YcgG family
LDP77_12830	COG1280	lysine exporter protein (LysE YggA)
LDP77_12835	COG2267	carboxylic ester hydrolase activity
LDP77_12840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LDP77_12845	COG0187	DNA topoisomerase II activity
LDP77_12850	COG1832	CoA-binding protein
LDP77_12855	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LDP77_12860	COG4841	protein insertion into membrane
LDP77_12865	COG0824	Thioesterase
LDP77_12895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDP77_12900	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LDP77_12920	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LDP77_12955	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LDP77_12960	COG2068	MobA-Related Protein
LDP77_12965	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LDP77_13020	COG1183	phosphatidylcholine synthase activity
LDP77_13035	COG2814	Major facilitator Superfamily
LDP77_13040	COG1683	Conserved Protein
LDP77_13045	COG1302	Protein conserved in bacteria
LDP77_13060	COG1295	ribonuclease BN
LDP77_13075	COG2814	Major facilitator Superfamily
LDP77_13085	COG2814	Major facilitator Superfamily
LDP77_13090	COG0789	Transcriptional regulator
LDP77_13100	COG0288	reversible hydration of carbon dioxide
LDP77_13105	COG0659	secondary active sulfate transmembrane transporter activity
LDP77_13110	COG0745	RESPONSE REGULATOR receiver
LDP77_13115	COG5002	protein histidine kinase activity
LDP77_13125	COG0477	Major facilitator Superfamily
LDP77_13130	COG4282	regulation of fungal-type cell wall biogenesis
LDP77_13135	COG0531	amino acid
LDP77_13145	COG0860	N-Acetylmuramoyl-L-alanine amidase
LDP77_13150	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LDP77_13225	COG1363	Peptidase, m42
LDP77_13235	COG1114	Component of the transport system for branched-chain amino acids
LDP77_13255	COG0004	ammonium transporteR
LDP77_13270	COG1252	NADH dehydrogenase
LDP77_13275	COG0679	Auxin Efflux Carrier
LDP77_13280	COG0281	malic enzyme
LDP77_13285	COG1473	amidohydrolase
LDP77_13310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LDP77_13315	COG0163	prenyltransferase activity
LDP77_13320	COG0583	DNA-binding transcription factor activity
LDP77_13325	COG0679	Auxin Efflux Carrier
LDP77_13345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_13350	COG0247	lactate metabolic process
LDP77_13355	COG0277	FAD linked oxidase domain protein
LDP77_13360	COG3835	regulator
LDP77_13365	COG0693	protein deglycase activity
LDP77_13375	COG2610	gluconate transmembrane transporter activity
LDP77_13395	COG1131	(ABC) transporter
LDP77_13405	COG2197	response regulator
LDP77_13440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_13450	COG0586	Pfam SNARE associated Golgi protein
LDP77_13455	COG1515	deoxyribonuclease V activity
LDP77_13460	COG0584	glycerophosphoryl diester phosphodiesterase
LDP77_13465	COG3153	acetyltransferase
LDP77_13465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDP77_13475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDP77_13480	COG0531	amino acid
LDP77_13545	COG5444	nuclease activity
LDP77_13555	COG5444	nuclease activity
LDP77_13570	COG0534	Mate efflux family protein
LDP77_13575	COG1566	PFAM secretion protein HlyD family protein
LDP77_13585	COG1846	Transcriptional regulator
LDP77_13590	COG0708	Exodeoxyribonuclease III
LDP77_13610	COG0673	inositol 2-dehydrogenase activity
LDP77_13615	COG1349	DNA-binding transcription factor activity
LDP77_13620	COG3853	Toxic anion resistance protein (TelA)
LDP77_13630	COG2310	stress, protein
LDP77_13635	COG2310	stress, protein
LDP77_13640	COG2310	stress, protein
LDP77_13645	COG0737	Belongs to the 5'-nucleotidase family
LDP77_13655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LDP77_13660	COG1131	(ABC) transporter
LDP77_13670	COG2084	Dehydrogenase
LDP77_13675	COG1278	Cold shock
LDP77_13680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP77_13690	COG0028	Belongs to the TPP enzyme family
LDP77_13695	COG1278	Cold shock
LDP77_13720	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_13725	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_13735	COG0427	acetyl-CoA hydrolase
LDP77_13740	COG3279	Response regulator of the LytR AlgR family
LDP77_13745	COG2323	membrane
LDP77_13750	COG2814	Major facilitator Superfamily
LDP77_13755	COG1388	LysM domain
LDP77_13755	COG3584	3D domain protein
LDP77_13760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LDP77_13785	COG3340	Belongs to the peptidase S51 family
LDP77_13810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LDP77_13840	COG2318	DinB family
LDP77_13850	COG0579	oxidoreductase
LDP77_13875	COG0488	(ABC) transporter
LDP77_13880	COG1486	melibiose metabolic process
LDP77_13885	COG0395	ABC-type sugar transport system, permease component
LDP77_13890	COG1175	transmembrane transport
LDP77_13895	COG1653	transport
LDP77_13900	COG1609	Transcriptional regulator
LDP77_13910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDP77_13930	COG1929	Belongs to the glycerate kinase type-1 family
LDP77_13935	COG2610	gluconate transmembrane transporter activity
LDP77_13940	COG3835	regulator
LDP77_13945	COG1454	alcohol dehydrogenase
LDP77_13950	COG3152	Membrane
LDP77_13965	COG0492	ferredoxin-NADP+ reductase activity
LDP77_13975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP77_13980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_13990	COG3152	Membrane
LDP77_14010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDP77_14020	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LDP77_14035	COG2390	Transcriptional regulator
LDP77_14065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LDP77_14075	COG1695	Transcriptional regulator
LDP77_14080	COG0501	Belongs to the peptidase M48B family
LDP77_14085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP77_14090	COG1742	UPF0060 membrane protein
LDP77_14095	COG2182	Extracellular solute-binding protein
LDP77_14115	COG2031	fatty acid transporter
LDP77_14140	COG2391	methyltransferase activity
LDP77_14205	COG0756	dUTP diphosphatase activity
LDP77_14225	COG0583	DNA-binding transcription factor activity
LDP77_14240	COG0456	acetyltransferase
LDP77_14245	COG2211	Major facilitator Superfamily
LDP77_14275	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_14280	COG1063	alcohol dehydrogenase
LDP77_14305	COG0025	NhaP-type Na H and K H
LDP77_14310	COG1253	flavin adenine dinucleotide binding
LDP77_14335	COG4608	Belongs to the ABC transporter superfamily
LDP77_14345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDP77_14350	COG0601	transmembrane transport
LDP77_14355	COG0747	negative chemotaxis
LDP77_14365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_14385	COG1525	nuclease
LDP77_14395	COG0579	oxidoreductase
LDP77_14400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LDP77_14405	COG0561	phosphatase activity
LDP77_14420	COG0668	transmembrane transport
LDP77_14450	COG2309	aminopeptidase activity
LDP77_14455	COG1414	Transcriptional regulator
LDP77_14460	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDP77_14465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LDP77_14470	COG0277	FAD linked oxidase domain protein
LDP77_14475	COG0247	lactate metabolic process
LDP77_14480	COG0277	FAD linked oxidase domain protein
LDP77_14485	COG1620	l-lactate permease
LDP77_14505	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LDP77_14510	COG1131	(ABC) transporter
LDP77_14530	COG1595	DNA-templated transcription, initiation
LDP77_14550	COG4682	membrane
LDP77_14565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_14570	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_14575	COG0598	Magnesium transport protein CorA
LDP77_14580	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LDP77_14590	COG2323	membrane
LDP77_14595	COG1876	peptidase activity
LDP77_14610	COG5002	protein histidine kinase activity
LDP77_14615	COG0745	RESPONSE REGULATOR receiver
LDP77_14635	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDP77_14650	COG2814	Major facilitator Superfamily
LDP77_14655	COG1764	response to oxidative stress
LDP77_14665	COG2311	Membrane
LDP77_14725	COG0347	Belongs to the P(II) protein family
LDP77_14730	COG0004	ammonium transporteR
LDP77_14735	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LDP77_14750	COG0596	Alpha beta hydrolase
LDP77_14770	COG0456	acetyltransferase
LDP77_14770	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LDP77_14775	COG1960	acyl-CoA dehydrogenase activity
LDP77_14815	COG4604	ABC transporter, ATP-binding protein
LDP77_14820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP77_14825	COG1492	cobalamin metabolic process
LDP77_14835	COG0531	amino acid
LDP77_14845	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_14850	COG2404	hydrolase activity, acting on ester bonds
LDP77_14855	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LDP77_14865	COG1609	Transcriptional regulator
LDP77_14875	COG2271	Major facilitator Superfamily
LDP77_14880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDP77_14895	COG1233	COG1233 Phytoene dehydrogenase and related
LDP77_14900	COG0463	Glycosyl transferase, family 2
LDP77_14945	COG0804	urea catabolic process
LDP77_14955	COG0831	urea catabolic process
LDP77_14960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LDP77_14965	COG1388	LysM domain
LDP77_14965	COG0791	NLP P60 protein
LDP77_14970	COG1388	LysM domain
LDP77_14970	COG3584	3D domain protein
LDP77_14975	COG0778	Nitroreductase
LDP77_14980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LDP77_14985	COG0586	Pfam SNARE associated Golgi protein
LDP77_14995	COG0400	carboxylic ester hydrolase activity
LDP77_15000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDP77_15005	COG2244	polysaccharide biosynthetic process
LDP77_15010	COG0697	spore germination
LDP77_15015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP77_15035	COG1132	(ABC) transporter
LDP77_15060	COG4195	phage-related replication protein
LDP77_15075	COG0783	Belongs to the Dps family
LDP77_15085	COG5577	PFAM Coat F domain
LDP77_15090	COG1253	flavin adenine dinucleotide binding
LDP77_15105	COG0517	IMP dehydrogenase activity
LDP77_15105	COG0516	GMP reductase activity
LDP77_15115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDP77_15115	COG0723	plastoquinol--plastocyanin reductase activity
LDP77_15130	COG0287	Prephenate dehydrogenase
LDP77_15140	COG1605	Chorismate mutase
LDP77_15140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LDP77_15150	COG2059	Chromate
LDP77_15155	COG2059	Chromate
LDP77_15165	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LDP77_15170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDP77_15175	COG2508	Transcriptional regulator
LDP77_15180	COG0011	TIGRFAM Protein of
LDP77_15185	COG1388	LysM domain
LDP77_15185	COG0791	NLP P60 protein
LDP77_15195	COG0753	catalase activity
LDP77_15205	COG0733	neurotransmitter:sodium symporter activity
LDP77_15250	COG0730	response to heat
LDP77_15255	COG1902	pentaerythritol trinitrate reductase activity
LDP77_15270	COG2205	protein histidine kinase activity
LDP77_15280	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LDP77_15310	COG0640	Transcriptional regulator
LDP77_15320	COG0778	Nitroreductase
LDP77_15335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LDP77_15340	COG0860	N-Acetylmuramoyl-L-alanine amidase
LDP77_15340	COG3103	Sh3 type 3 domain protein
LDP77_15340	COG4991	sh3 domain protein
LDP77_15345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LDP77_15350	COG2002	toxin-antitoxin pair type II binding
LDP77_15355	COG2318	DinB family
LDP77_15360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDP77_15375	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LDP77_15380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_15395	COG2211	Major facilitator Superfamily
LDP77_15400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_15405	COG1597	lipid kinase activity
LDP77_15415	COG0372	Belongs to the citrate synthase family
LDP77_15420	COG0583	DNA-binding transcription factor activity
LDP77_15425	COG0697	spore germination
LDP77_15430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP77_15450	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_15450	COG2202	Pas domain
LDP77_15455	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_15490	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_15495	COG2261	transglycosylase associated protein
LDP77_15510	COG0740	serine-type endopeptidase activity
LDP77_15525	COG1027	Aspartate ammonia-lyase
LDP77_15530	COG0252	asparaginase activity
LDP77_15535	COG1396	sequence-specific DNA binding
LDP77_15555	COG0640	Transcriptional regulator
LDP77_15575	COG0531	amino acid
LDP77_15580	COG1959	2 iron, 2 sulfur cluster binding
LDP77_15600	COG0281	malic enzyme
LDP77_15605	COG2746	aminoglycoside 3-N-acetyltransferase activity
LDP77_15615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_15620	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_15630	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDP77_15635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDP77_15650	COG0477	Major facilitator Superfamily
LDP77_15655	COG1846	Transcriptional regulator
LDP77_15660	COG0789	Transcriptional regulator
LDP77_15665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_15700	COG1819	glycosyl
LDP77_15720	COG1902	pentaerythritol trinitrate reductase activity
LDP77_15730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDP77_15745	COG2814	Major facilitator Superfamily
LDP77_15755	COG1228	amidohydrolase
LDP77_15765	COG1316	TRANSCRIPTIONal
LDP77_15770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_15790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LDP77_15800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDP77_15865	COG0531	amino acid
LDP77_15880	COG3764	Sortase (surface protein transpeptidase)
LDP77_15885	COG0730	response to heat
LDP77_15890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_15895	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LDP77_15905	COG2130	NADP-dependent
LDP77_15925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_15940	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LDP77_15950	COG0501	Belongs to the peptidase M48B family
LDP77_15990	COG0131	Imidazoleglycerol-phosphate dehydratase
LDP77_15990	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LDP77_16005	COG2076	Multidrug Resistance protein
LDP77_16010	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LDP77_16015	COG1278	Cold shock
LDP77_16020	COG2323	membrane
LDP77_16035	COG2910	NAD(P)H-binding
LDP77_16060	COG3546	catalase activity
LDP77_16065	COG4607	ABC-type enterochelin transport system periplasmic component
LDP77_16070	COG4604	ABC transporter, ATP-binding protein
LDP77_16075	COG4605	iron ion homeostasis
LDP77_16080	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP77_16085	COG3773	Cell wall hydrolase
LDP77_16110	COG1063	alcohol dehydrogenase
LDP77_16115	COG3775	system Galactitol-specific IIC component
LDP77_16120	COG3414	Phosphotransferase system galactitol-specific IIB component
LDP77_16125	COG3414	Phosphotransferase system galactitol-specific IIB component
LDP77_16140	COG2249	NAD(P)H dehydrogenase (quinone) activity
LDP77_16165	COG1349	DNA-binding transcription factor activity
LDP77_16180	COG1193	negative regulation of DNA recombination
LDP77_16190	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LDP77_16195	COG1396	sequence-specific DNA binding
LDP77_16200	COG0861	Integral membrane protein TerC family
LDP77_16205	COG1609	Transcriptional regulator
LDP77_16210	COG1959	2 iron, 2 sulfur cluster binding
LDP77_16270	COG3773	Cell wall hydrolase
LDP77_16275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LDP77_16305	COG3546	catalase activity
LDP77_16325	COG1280	lysine exporter protein (LysE YggA)
LDP77_16330	COG1917	Cupin 2, conserved barrel domain protein
LDP77_16330	COG2207	Transcriptional regulator
LDP77_16335	COG4585	Histidine kinase
LDP77_16345	COG0584	glycerophosphoryl diester phosphodiesterase
LDP77_16360	COG3209	COG3209 Rhs family protein
LDP77_16380	COG1819	glycosyl
LDP77_16385	COG0456	acetyltransferase
LDP77_16400	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LDP77_16410	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LDP77_16430	COG0346	lactoylglutathione lyase activity
LDP77_16435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LDP77_16450	COG1136	(ABC) transporter
LDP77_16455	COG0577	efflux transmembrane transporter activity
LDP77_16460	COG5002	protein histidine kinase activity
LDP77_16460	COG3850	Histidine kinase
LDP77_16485	COG5002	protein histidine kinase activity
LDP77_16490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_16495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDP77_16520	COG4989	oxidoreductase activity
LDP77_16530	COG0697	spore germination
LDP77_16535	COG2207	Transcriptional regulator
LDP77_16535	COG1917	Cupin 2, conserved barrel domain protein
LDP77_16610	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
LDP77_16620	COG1301	dicarboxylic acid transport
LDP77_16625	COG2824	Alkylphosphonate utilization operon protein PhnA
LDP77_16655	COG0405	Gamma-glutamyltransferase
LDP77_16660	COG1073	alpha beta
LDP77_16675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDP77_16680	COG4521	taurine ABC transporter
LDP77_16685	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LDP77_16690	COG2175	clavaminate synthase activity
LDP77_16695	COG2814	Major facilitator Superfamily
LDP77_16715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_16725	COG1960	acyl-CoA dehydrogenase activity
LDP77_16730	COG1063	alcohol dehydrogenase
LDP77_16735	COG0745	RESPONSE REGULATOR receiver
LDP77_16740	COG0642	Histidine kinase
LDP77_16745	COG1136	(ABC) transporter
LDP77_16750	COG0577	efflux transmembrane transporter activity
LDP77_16760	COG0412	Dienelactone hydrolase
LDP77_16765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP77_16785	COG0730	response to heat
LDP77_16790	COG0425	Belongs to the sulfur carrier protein TusA family
LDP77_16795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP77_16795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDP77_16800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDP77_16800	COG0425	Belongs to the sulfur carrier protein TusA family
LDP77_16810	COG2210	Belongs to the sulfur carrier protein TusA family
LDP77_16815	COG0425	Belongs to the sulfur carrier protein TusA family
LDP77_16820	COG1937	Protein conserved in bacteria
LDP77_16840	COG0583	DNA-binding transcription factor activity
LDP77_16855	COG2188	Transcriptional regulator
LDP77_16865	COG2723	6-phospho-beta-galactosidase activity
LDP77_16895	COG1280	lysine exporter protein (LysE YggA)
LDP77_16910	COG0583	DNA-binding transcription factor activity
LDP77_16915	COG2814	Major facilitator Superfamily
LDP77_16920	COG0346	lactoylglutathione lyase activity
LDP77_16940	COG5001	Diguanylate cyclase
LDP77_16940	COG3300	MHYT domain
LDP77_16945	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LDP77_16965	COG0778	Nitroreductase
LDP77_16970	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_16990	COG1704	LemA family
LDP77_17000	COG1733	regulation of RNA biosynthetic process
LDP77_17005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LDP77_17010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LDP77_17015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP77_17030	COG2304	oxidoreductase activity
LDP77_17040	COG0346	lactoylglutathione lyase activity
LDP77_17045	COG2808	Putative FMN-binding domain
LDP77_17085	COG4807	Protein conserved in bacteria
LDP77_17095	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
LDP77_17100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_17105	COG1278	Cold shock
LDP77_17115	COG1278	Cold shock
LDP77_17130	COG0747	negative chemotaxis
LDP77_17135	COG0601	transmembrane transport
LDP77_17140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDP77_17145	COG0444	Belongs to the ABC transporter superfamily
LDP77_17150	COG4608	Belongs to the ABC transporter superfamily
LDP77_17160	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LDP77_17165	COG1301	dicarboxylic acid transport
LDP77_17180	COG0477	Major facilitator Superfamily
LDP77_17215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDP77_17220	COG0659	secondary active sulfate transmembrane transporter activity
LDP77_17230	COG2211	Major facilitator Superfamily
LDP77_17240	COG1691	(AIR) carboxylase
LDP77_17245	COG1606	tRNA processing
LDP77_17250	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_17260	COG1904	glucuronate isomerase
LDP77_17295	COG2329	Antibiotic biosynthesis monooxygenase
LDP77_17335	COG3655	Transcriptional regulator
LDP77_17345	COG0583	DNA-binding transcription factor activity
LDP77_17350	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_17365	COG1609	Transcriptional regulator
LDP77_17370	COG1082	Xylose isomerase domain protein TIM barrel
LDP77_17375	COG0673	inositol 2-dehydrogenase activity
LDP77_17395	COG3718	enzyme involved in inositol metabolism
LDP77_17400	COG3962	Belongs to the TPP enzyme family
LDP77_17405	COG1349	DNA-binding transcription factor activity
LDP77_17410	COG0191	fructose-bisphosphate aldolase activity
LDP77_17415	COG1082	Xylose isomerase domain protein TIM barrel
LDP77_17420	COG2814	Major facilitator Superfamily
LDP77_17435	COG1064	alcohol dehydrogenase
LDP77_17440	COG0789	Transcriptional regulator
LDP77_17450	COG0662	Cupin 2, conserved barrel domain protein
LDP77_17465	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_17470	COG1278	Cold shock
LDP77_17515	COG0598	Magnesium transport protein CorA
LDP77_17520	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP77_17530	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_17545	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_17560	COG4335	DNA alkylation repair
LDP77_17565	COG0454	-acetyltransferase
LDP77_17585	COG2814	Major facilitator Superfamily
LDP77_17590	COG0574	Belongs to the PEP-utilizing enzyme family
LDP77_17590	COG3848	Pyruvate phosphate dikinase
LDP77_17595	COG0574	Belongs to the PEP-utilizing enzyme family
LDP77_17595	COG3848	Pyruvate phosphate dikinase
LDP77_17610	COG2186	Transcriptional regulator
LDP77_17630	COG3619	membrane
LDP77_17635	COG1349	DNA-binding transcription factor activity
LDP77_17640	COG0561	phosphatase activity
LDP77_17650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDP77_17670	COG1280	lysine exporter protein (LysE YggA)
LDP77_17705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LDP77_17725	COG2814	Major facilitator Superfamily
LDP77_17730	COG2160	L-arabinose isomerase activity
LDP77_17745	COG1609	Transcriptional regulator
LDP77_17750	COG1078	dGTPase activity
LDP77_17770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LDP77_17775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LDP77_17780	COG1918	ferrous iron import across plasma membrane
LDP77_17780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LDP77_17805	COG1846	Transcriptional regulator
LDP77_17840	COG0697	spore germination
LDP77_17845	COG1388	LysM domain
LDP77_17845	COG0791	NLP P60 protein
LDP77_17850	COG2258	MOSC domain
LDP77_17855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDP77_17890	COG4974	Belongs to the 'phage' integrase family
LDP77_17935	COG1309	transcriptional regulator
LDP77_17940	COG3844	kynureninase activity
LDP77_17945	COG1113	amino acid transport
LDP77_17950	COG3483	tryptophan 2,3-dioxygenase activity
LDP77_17955	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LDP77_17960	COG1942	4-Oxalocrotonate Tautomerase
LDP77_17990	COG0251	oxidation-reduction process
LDP77_18005	COG0431	NADPH-dependent FMN reductase
LDP77_18010	COG0196	riboflavin kinase activity
LDP77_18015	COG2368	4-hydroxyphenylacetate
LDP77_18035	COG0789	Transcriptional regulator
LDP77_18070	COG5646	InterPro IPR014922
LDP77_18125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDP77_18135	COG2258	MOSC domain
LDP77_18150	COG0477	Major facilitator Superfamily
LDP77_18155	COG0583	DNA-binding transcription factor activity
LDP77_18160	COG2070	2-Nitropropane dioxygenase
LDP77_18165	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LDP77_18175	COG1376	ErfK ybiS ycfS ynhG family protein
LDP77_18205	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_18210	COG2188	Transcriptional regulator
LDP77_18220	COG1501	Belongs to the glycosyl hydrolase 31 family
LDP77_18230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LDP77_18240	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LDP77_18250	COG0300	oxidoreductase activity
LDP77_18260	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDP77_18260	COG0596	Alpha beta hydrolase
LDP77_18265	COG1309	transcriptional regulator
LDP77_18275	COG1733	regulation of RNA biosynthetic process
LDP77_18280	COG2249	NAD(P)H dehydrogenase (quinone) activity
LDP77_18285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDP77_18290	COG2226	methyltransferase
LDP77_18305	COG1942	4-Oxalocrotonate Tautomerase
LDP77_18310	COG0583	DNA-binding transcription factor activity
LDP77_18315	COG0047	phosphoribosylformylglycinamidine synthase activity
LDP77_18320	COG1522	sequence-specific DNA binding
LDP77_18330	COG2267	carboxylic ester hydrolase activity
LDP77_18340	COG1335	isochorismatase
LDP77_18350	COG0346	lactoylglutathione lyase activity
LDP77_18355	COG2259	Doxx family
LDP77_18360	COG0039	L-malate dehydrogenase activity
LDP77_18365	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
LDP77_18370	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
LDP77_18390	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_18390	COG1454	alcohol dehydrogenase
LDP77_18400	COG4302	ethanolamine ammonia-lyase activity
LDP77_18405	COG4303	Ethanolamine ammonia lyase large subunit
LDP77_18415	COG4917	ethanolamine utilization protein
LDP77_18425	COG3192	ethanolamine utilization protein
LDP77_18455	COG1309	transcriptional regulator
LDP77_18460	COG2076	Multidrug Resistance protein
LDP77_18470	COG0477	Major facilitator Superfamily
LDP77_18475	COG1609	Transcriptional regulator
LDP77_18480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDP77_18505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDP77_18515	COG2851	Citrate transporter
LDP77_18525	COG0477	Major facilitator Superfamily
LDP77_18535	COG0477	Major facilitator Superfamily
LDP77_18540	COG1309	transcriptional regulator
LDP77_18565	COG2318	DinB family
LDP77_18570	COG0156	8-amino-7-oxononanoate synthase activity
LDP77_18575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDP77_18595	COG1378	Sugar-specific transcriptional regulator TrmB
LDP77_18600	COG0697	spore germination
LDP77_18610	COG0583	DNA-binding transcription factor activity
LDP77_18655	COG1266	CAAX protease self-immunity
LDP77_18680	COG0252	asparaginase activity
LDP77_18700	COG1695	Transcriptional regulator
LDP77_18710	COG0656	L-ascorbic acid biosynthetic process
LDP77_18720	COG0583	DNA-binding transcription factor activity
LDP77_18730	COG2814	Major facilitator Superfamily
LDP77_18740	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
LDP77_18750	COG0281	malic enzyme
LDP77_18755	COG2404	hydrolase activity, acting on ester bonds
LDP77_18825	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LDP77_18890	COG3339	Conserved Protein
LDP77_18905	COG3708	Transcriptional regulator
LDP77_18905	COG2207	Transcriptional regulator
LDP77_18920	COG1357	PFAM Pentapeptide repeats (8 copies)
LDP77_18925	COG2249	NAD(P)H dehydrogenase (quinone) activity
LDP77_18930	COG1733	regulation of RNA biosynthetic process
LDP77_18960	COG0303	'Molybdopterin
LDP77_18970	COG0521	Mo-molybdopterin cofactor biosynthetic process
LDP77_18975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LDP77_18980	COG1079	Belongs to the binding-protein-dependent transport system permease family
LDP77_18985	COG4603	Belongs to the binding-protein-dependent transport system permease family
LDP77_18990	COG3845	ABC transporter
LDP77_19005	COG2244	polysaccharide biosynthetic process
LDP77_19025	COG2828	Protein conserved in bacteria
LDP77_19030	COG0583	DNA-binding transcription factor activity
LDP77_19035	COG2851	Citrate transporter
LDP77_19060	COG0670	Belongs to the BI1 family
LDP77_19080	COG0791	NLP P60 protein
LDP77_19085	COG2814	Major facilitator Superfamily
LDP77_19090	COG1846	Transcriptional regulator
LDP77_19110	COG1278	Cold shock
LDP77_19125	COG1113	amino acid transport
LDP77_19130	COG1113	amino acid transport
LDP77_19135	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_19140	COG0506	proline dehydrogenase activity
LDP77_19145	COG3878	Protein conserved in bacteria
LDP77_19165	COG0860	N-Acetylmuramoyl-L-alanine amidase
LDP77_19175	COG3300	MHYT domain
LDP77_19175	COG5001	Diguanylate cyclase
LDP77_19230	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LDP77_19235	COG5609	conserved protein (DUF2294)
LDP77_19245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LDP77_19275	COG0454	-acetyltransferase
LDP77_19300	COG0789	Transcriptional regulator
LDP77_19305	COG0667	Aldo Keto reductase
LDP77_19315	COG0789	Transcriptional regulator
LDP77_19340	COG1621	beta-fructofuranosidase activity
LDP77_19345	COG4980	gas vesicle protein
LDP77_19370	COG1752	Esterase of the alpha-beta hydrolase superfamily
LDP77_19375	COG0577	efflux transmembrane transporter activity
LDP77_19380	COG1136	(ABC) transporter
LDP77_19390	COG0642	Histidine kinase
LDP77_19405	COG1289	transmembrane transporter activity
LDP77_19410	COG1937	Protein conserved in bacteria
LDP77_19415	COG3209	COG3209 Rhs family protein
LDP77_19425	COG3973	AAA domain
LDP77_19430	COG1024	Enoyl-CoA hydratase
LDP77_19435	COG1733	regulation of RNA biosynthetic process
LDP77_19450	COG2124	cytochrome p450
LDP77_19455	COG2259	Doxx family
LDP77_19460	COG0463	Glycosyl transferase, family 2
LDP77_19470	COG0463	Glycosyl transferase, family 2
LDP77_19485	COG1388	LysM domain
LDP77_19485	COG0791	NLP P60 protein
LDP77_19500	COG1846	Transcriptional regulator
LDP77_19510	COG1595	DNA-templated transcription, initiation
LDP77_19515	COG0726	polysaccharide deacetylase
LDP77_19520	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LDP77_19535	COG0833	amino acid
LDP77_19550	COG0405	Gamma-glutamyltransferase
LDP77_19570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDP77_19575	COG0569	domain protein
LDP77_19585	COG1522	sequence-specific DNA binding
LDP77_19595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDP77_19600	COG0745	RESPONSE REGULATOR receiver
LDP77_19605	COG2770	Histidine kinase
LDP77_19605	COG2205	protein histidine kinase activity
LDP77_19610	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LDP77_19615	COG1607	acyl-coa hydrolase
LDP77_19620	COG1802	Transcriptional regulator
LDP77_19625	COG0697	spore germination
LDP77_19635	COG0006	proline dipeptidase activity
LDP77_19655	COG2249	NAD(P)H dehydrogenase (quinone) activity
LDP77_19660	COG5522	Integral membrane protein (intg_mem_TP0381)
LDP77_19670	COG1174	glycine betaine transport
LDP77_19675	COG0517	IMP dehydrogenase activity
LDP77_19675	COG1125	glycine betaine transport
LDP77_19690	COG2814	Major facilitator Superfamily
LDP77_19700	COG0395	ABC-type sugar transport system, permease component
LDP77_19720	COG1609	Transcriptional regulator
LDP77_19725	COG2205	protein histidine kinase activity
LDP77_19730	COG0730	response to heat
LDP77_19735	COG1301	dicarboxylic acid transport
LDP77_19750	COG0753	catalase activity
LDP77_19775	COG1368	sulfuric ester hydrolase activity
LDP77_19785	COG0697	spore germination
LDP77_19790	COG1902	pentaerythritol trinitrate reductase activity
LDP77_19805	COG1113	amino acid transport
LDP77_19810	COG5505	Protein of unknown function (DUF819)
LDP77_19815	COG1309	transcriptional regulator
LDP77_19825	COG0583	DNA-binding transcription factor activity
LDP77_19830	COG0730	response to heat
LDP77_19835	COG1247	-acetyltransferase
LDP77_19840	COG2910	NAD(P)H-binding
LDP77_19845	COG1285	pathogenesis
LDP77_19850	COG2226	methyltransferase
LDP77_19855	COG4195	phage-related replication protein
LDP77_19860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP77_19875	COG1113	amino acid transport
LDP77_19905	COG0463	Glycosyl transferase, family 2
LDP77_19925	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LDP77_19930	COG2514	catechol 2,3-dioxygenase activity
LDP77_19950	COG1280	lysine exporter protein (LysE YggA)
LDP77_19955	COG1115	amino acid carrier protein
LDP77_19965	COG0385	Bile acid
LDP77_19970	COG0668	transmembrane transport
LDP77_19975	COG2340	Cysteine-rich secretory protein family
LDP77_19980	COG1253	flavin adenine dinucleotide binding
LDP77_19990	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LDP77_19995	COG0589	response to stress
LDP77_20005	COG0205	6-phosphofructokinase activity
LDP77_20010	COG1388	LysM domain
LDP77_20010	COG0791	NLP P60 protein
LDP77_20020	COG0432	Pfam Uncharacterised protein family UPF0047
LDP77_20025	COG0697	spore germination
LDP77_20030	COG0814	amino acid
LDP77_20055	COG1131	(ABC) transporter
LDP77_20070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDP77_20085	COG0584	glycerophosphoryl diester phosphodiesterase
LDP77_20095	COG1131	(ABC) transporter
LDP77_20110	COG0706	membrane insertase activity
LDP77_20115	COG1263	PTS System
LDP77_20115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP77_20120	COG3711	transcriptional antiterminator
LDP77_20125	COG2190	(PTS) system
LDP77_20130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LDP77_20145	COG0772	Belongs to the SEDS family
LDP77_20150	COG0659	secondary active sulfate transmembrane transporter activity
LDP77_20155	COG0813	purine-nucleoside phosphorylase activity
LDP77_20170	COG0671	phosphoesterase, PA-phosphatase related
LDP77_20175	COG4326	sporulation control protein
LDP77_20180	COG2815	serine threonine protein kinase
LDP77_20180	COG0515	serine threonine protein kinase
LDP77_20205	COG4479	Belongs to the UPF0346 family
LDP77_20210	COG3594	Acyltransferase
LDP77_20225	COG1509	lysine 2,3-aminomutase activity
LDP77_20230	COG0456	acetyltransferase
LDP77_20235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDP77_20240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LDP77_20245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LDP77_20250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDP77_20255	COG1301	dicarboxylic acid transport
LDP77_20265	COG4191	Histidine kinase
LDP77_20295	COG2755	lipolytic protein G-D-S-L family
LDP77_20300	COG1999	signal sequence binding
LDP77_20310	COG1307	EDD domain protein, DegV family
LDP77_20320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LDP77_20330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LDP77_20335	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LDP77_20340	COG0788	formyltetrahydrofolate deformylase activity
LDP77_20370	COG0076	glutamate decarboxylase activity
LDP77_20390	COG0415	Belongs to the DNA photolyase family
LDP77_20395	COG3852	Histidine kinase
LDP77_20415	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_20425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LDP77_20435	COG4846	Membrane protein involved in cytochrome C biogenesis
LDP77_20440	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
LDP77_20445	COG0785	Cytochrome C biogenesis protein
LDP77_20455	COG1132	(ABC) transporter
LDP77_20460	COG1132	(ABC) transporter
LDP77_20480	COG4224	UPF0291 protein
LDP77_20485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LDP77_20510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LDP77_20515	COG0531	amino acid
LDP77_20525	COG0174	glutamine synthetase
LDP77_20530	COG0789	Transcriptional regulator
LDP77_20535	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LDP77_20540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LDP77_20545	COG2860	membrane
LDP77_20550	COG0464	growth
LDP77_20560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LDP77_20570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LDP77_20575	COG0531	amino acid
LDP77_20585	COG4550	Control of competence regulator ComK, YlbF/YmcA
LDP77_20590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LDP77_20595	COG1013	pyruvate-flavodoxin oxidoreductase activity
LDP77_20600	COG0674	pyruvate-flavodoxin oxidoreductase activity
LDP77_20600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LDP77_20615	COG2359	stage V sporulation protein S
LDP77_20620	COG1692	metallophosphoesterase
LDP77_20630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LDP77_20635	COG1058	Belongs to the CinA family
LDP77_20635	COG1546	Belongs to the CinA family
LDP77_20640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LDP77_20645	COG1426	Protein conserved in bacteria
LDP77_20660	COG0300	oxidoreductase activity
LDP77_20665	COG0612	Peptidase, M16
LDP77_20670	COG0612	Peptidase, M16
LDP77_20675	COG1079	Belongs to the binding-protein-dependent transport system permease family
LDP77_20680	COG4603	Belongs to the binding-protein-dependent transport system permease family
LDP77_20685	COG3845	ABC transporter
LDP77_20690	COG1744	ABC transporter substrate-binding protein PnrA-like
LDP77_20695	COG2188	Transcriptional regulator
LDP77_20700	COG4980	gas vesicle protein
LDP77_20700	COG1674	ftsk spoiiie
LDP77_20710	COG0740	serine-type endopeptidase activity
LDP77_20715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LDP77_20725	COG0527	aspartate kinase activity
LDP77_20730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDP77_20735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LDP77_20740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDP77_20745	COG1873	PFAM PRC-barrel domain
LDP77_20750	COG0612	Peptidase, M16
LDP77_20755	COG0726	polysaccharide deacetylase
LDP77_20760	COG1185	polyribonucleotide nucleotidyltransferase activity
LDP77_20765	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LDP77_20770	COG0196	riboflavin kinase activity
LDP77_20780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LDP77_20785	COG1550	Protein conserved in bacteria
LDP77_20795	COG1358	cellular component organization or biogenesis
LDP77_20800	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LDP77_20805	COG0195	Participates in both transcription termination and antitermination
LDP77_20810	COG0779	Required for maturation of 30S ribosomal subunits
LDP77_20815	COG2176	DNA-directed DNA polymerase activity
LDP77_20820	COG0442	prolyl-tRNA aminoacylation
LDP77_20825	COG0750	zinc metalloprotease
LDP77_20835	COG4589	Belongs to the CDS family
LDP77_20845	COG0233	cytoplasmic translational termination
LDP77_20855	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LDP77_20870	COG1191	sigma factor activity
LDP77_20875	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LDP77_20880	COG0835	chemotaxis
LDP77_20885	COG0643	Histidine kinase
LDP77_20885	COG2198	Histidine kinase
LDP77_20890	COG2201	protein-glutamate methylesterase activity
LDP77_20895	COG0455	bacterial-type flagellum organization
LDP77_20900	COG1419	protein localization to endoplasmic reticulum
LDP77_20905	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LDP77_20910	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LDP77_20915	COG1684	flagellar biosynthetic protein fliR
LDP77_20920	COG1987	bacterial-type flagellum assembly
LDP77_20925	COG1338	Plays a role in the flagellum-specific transport system
LDP77_20930	COG3190	flagellar
LDP77_20935	COG2201	protein-glutamate methylesterase activity
LDP77_20940	COG1776	CheC inhibitor of MCP methylation
LDP77_20940	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LDP77_20945	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LDP77_20955	COG1582	Flagellar protein (FlbD)
LDP77_20960	COG4786	Flagellar basal body rod
LDP77_20965	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LDP77_20980	COG2882	bacterial-type flagellum organization
LDP77_20985	COG1157	protein secretion by the type III secretion system
LDP77_20990	COG1317	bacterial-type flagellum organization
LDP77_20995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LDP77_21000	COG1766	The M ring may be actively involved in energy transduction
LDP77_21005	COG1677	Flagellar hook-basal body complex protein FliE
LDP77_21010	COG1558	bacterial-type flagellum-dependent cell motility
LDP77_21015	COG1815	bacterial-type flagellum-dependent cell motility
LDP77_21020	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LDP77_21025	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LDP77_21035	COG4974	Belongs to the 'phage' integrase family
LDP77_21040	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LDP77_21045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDP77_21050	COG0758	DNA mediated transformation
LDP77_21055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LDP77_21060	COG0045	succinate-CoA ligase (ADP-forming) activity
LDP77_21080	COG0335	large ribosomal subunit rRNA binding
LDP77_21090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LDP77_21100	COG1837	Belongs to the UPF0109 family
LDP77_21105	COG0228	four-way junction DNA binding
LDP77_21110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LDP77_21120	COG0552	protein localization to endoplasmic reticulum
LDP77_21125	COG1196	nuclear chromosome segregation
LDP77_21130	COG0571	ribonuclease III activity
LDP77_21140	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_21145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LDP77_21150	COG0416	fatty acid biosynthetic process
LDP77_21155	COG1349	DNA-binding transcription factor activity
LDP77_21160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LDP77_21165	COG1760	l-serine dehydratase
LDP77_21170	COG1760	l-serine dehydratase
LDP77_21180	COG1461	Dihydroxyacetone kinase
LDP77_21185	COG1302	Protein conserved in bacteria
LDP77_21190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LDP77_21200	COG1564	THIamine pyrophosphokinase
LDP77_21205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LDP77_21210	COG1162	GTPase activity
LDP77_21215	COG0515	serine threonine protein kinase
LDP77_21215	COG2815	serine threonine protein kinase
LDP77_21220	COG0631	protein serine/threonine phosphatase activity
LDP77_21230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDP77_21230	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDP77_21235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LDP77_21245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LDP77_21250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LDP77_21255	COG1758	RNA polymerase activity
LDP77_21260	COG0194	GDP metabolic process
LDP77_21265	COG2052	Domain of unknown function (DUF370)
LDP77_21270	COG1561	YicC-like family, N-terminal region
LDP77_21275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LDP77_21285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LDP77_21315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDP77_21320	COG0540	Belongs to the ATCase OTCase family
LDP77_21330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LDP77_21335	COG0564	pseudouridine synthase activity
LDP77_21340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LDP77_21355	COG3599	regulation of cell shape
LDP77_21360	COG2302	S4 RNA-binding domain
LDP77_21365	COG0762	integral membrane protein
LDP77_21370	COG1799	cell septum assembly
LDP77_21375	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LDP77_21385	COG1873	PFAM PRC-barrel domain
LDP77_21390	COG1191	sigma factor activity
LDP77_21395	COG1191	sigma factor activity
LDP77_21405	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LDP77_21410	COG0849	cell division
LDP77_21415	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LDP77_21420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LDP77_21425	COG0772	Belongs to the SEDS family
LDP77_21430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LDP77_21435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDP77_21440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LDP77_21445	COG0768	penicillin binding
LDP77_21450	COG0768	penicillin binding
LDP77_21455	COG4839	cell division protein FtsL
LDP77_21465	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LDP77_21475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LDP77_21480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LDP77_21485	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LDP77_21490	COG0439	Biotin carboxylase
LDP77_21495	COG0454	-acetyltransferase
LDP77_21505	COG1024	Enoyl-CoA hydratase
LDP77_21510	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LDP77_21515	COG1399	metal-binding, possibly nucleic acid-binding protein
LDP77_21520	COG1323	Belongs to the UPF0348 family
LDP77_21525	COG3480	Lon protease (S16) C-terminal proteolytic domain
LDP77_21530	COG1752	Esterase of the alpha-beta hydrolase superfamily
LDP77_21535	COG3314	Sporulation integral membrane protein YlbJ
LDP77_21540	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LDP77_21545	COG0742	ribosomal rna small subunit methyltransferase
LDP77_21555	COG4471	UPF0298 protein
LDP77_21560	COG3679	Belongs to the UPF0342 family
LDP77_21580	COG4347	Protein of unknown function (DUF1405)
LDP77_21590	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LDP77_21605	COG5582	Belongs to the UPF0302 family
LDP77_21610	COG0457	Tetratricopeptide repeat
LDP77_21615	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LDP77_21620	COG0287	Prephenate dehydrogenase
LDP77_21625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDP77_21630	COG0159	tryptophan synthase activity
LDP77_21640	COG0135	phosphoribosylanthranilate isomerase activity
LDP77_21645	COG0134	indole-3-glycerol-phosphate synthase activity
LDP77_21650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LDP77_21660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LDP77_21665	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LDP77_21670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LDP77_21675	COG0105	UTP biosynthetic process
LDP77_21680	COG0142	geranyltranstransferase activity
LDP77_21685	COG2226	methyltransferase
LDP77_21690	COG0142	geranyltranstransferase activity
LDP77_21700	COG0302	gtp cyclohydrolase
LDP77_21705	COG0776	regulation of translation
LDP77_21710	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LDP77_21745	COG2271	Major facilitator Superfamily
LDP77_21750	COG1304	FMN binding
LDP77_21755	COG0539	negative regulation of cytoplasmic translation
LDP77_21765	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LDP77_21780	COG2959	enzyme of heme biosynthesis
LDP77_21785	COG3409	Peptidoglycan-binding domain 1 protein
LDP77_21785	COG3773	Cell wall hydrolase
LDP77_21790	COG2339	peptidase activity
LDP77_21795	COG0252	asparaginase activity
LDP77_21800	COG0492	ferredoxin-NADP+ reductase activity
LDP77_21805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LDP77_21810	COG4862	establishment of competence for transformation
LDP77_21815	COG0789	Transcriptional regulator
LDP77_21820	COG1408	metallophosphoesterase
LDP77_21835	COG1266	CAAX protease self-immunity
LDP77_21840	COG0514	ATP-dependent DNA helicase (RecQ)
LDP77_21850	COG1141	Ferredoxin
LDP77_21855	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LDP77_21860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDP77_21865	COG0739	heme binding
LDP77_21870	COG5002	protein histidine kinase activity
LDP77_21875	COG0745	RESPONSE REGULATOR receiver
LDP77_21880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDP77_21885	COG1333	cytochrome c biogenesis protein
LDP77_21890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDP77_21895	COG1187	pseudouridine synthase activity
LDP77_21900	COG0700	Nucleoside recognition
LDP77_21905	COG2715	membrane protein required for spore maturation
LDP77_21910	COG1686	Belongs to the peptidase S11 family
LDP77_21915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LDP77_21920	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LDP77_21930	COG1547	Domain of unknown function (DUF309)
LDP77_21940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LDP77_21945	COG4086	secreted protein
LDP77_21955	COG0697	spore germination
LDP77_21970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDP77_22005	COG1686	Belongs to the peptidase S11 family
LDP77_22020	COG4974	Belongs to the 'phage' integrase family
LDP77_22030	COG0735	belongs to the Fur family
LDP77_22035	COG1300	Membrane
LDP77_22045	COG0494	nUDIX hydrolase
LDP77_22055	COG0667	Aldo Keto reductase
LDP77_22065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LDP77_22070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LDP77_22080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDP77_22085	COG1073	alpha beta
LDP77_22100	COG0300	oxidoreductase activity
LDP77_22105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP77_22110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDP77_22115	COG1902	pentaerythritol trinitrate reductase activity
LDP77_22120	COG1234	tRNA 3'-trailer cleavage
LDP77_22125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDP77_22130	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_22135	COG2508	Transcriptional regulator
LDP77_22155	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LDP77_22155	COG0167	dihydroorotate dehydrogenase activity
LDP77_22160	COG0493	'glutamate synthase
LDP77_22165	COG2195	Cleaves the N-terminal amino acid of tripeptides
LDP77_22170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LDP77_22175	COG0346	lactoylglutathione lyase activity
LDP77_22185	COG1376	ErfK ybiS ycfS ynhG family protein
LDP77_22190	COG4129	membrane
LDP77_22195	COG1126	abc transporter atp-binding protein
LDP77_22200	COG0765	amino acid transport
LDP77_22205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP77_22215	COG1703	isobutyryl-CoA mutase activity
LDP77_22220	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDP77_22220	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDP77_22225	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDP77_22225	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDP77_22230	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDP77_22235	COG0022	dehydrogenase e1 component
LDP77_22240	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LDP77_22245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDP77_22260	COG0280	phosphate acetyltransferase
LDP77_22265	COG3829	transcription factor binding
LDP77_22265	COG3290	protein histidine kinase activity
LDP77_22275	COG0584	glycerophosphoryl diester phosphodiesterase
LDP77_22280	COG3093	addiction module antidote protein HigA
LDP77_22285	COG3104	oligopeptide transport
LDP77_22295	COG0750	zinc metalloprotease
LDP77_22300	COG0497	DNA recombination
LDP77_22310	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LDP77_22325	COG1722	exodeoxyribonuclease VII activity
LDP77_22335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDP77_22340	COG1302	Protein conserved in bacteria
LDP77_22345	COG0439	Biotin carboxylase
LDP77_22350	COG0511	ligase activity, forming carbon-carbon bonds
LDP77_22390	COG3854	ATPases associated with a variety of cellular activities
LDP77_22400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LDP77_22405	COG0006	proline dipeptidase activity
LDP77_22410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LDP77_22420	COG3872	metal-dependent enzyme
LDP77_22430	COG1752	Esterase of the alpha-beta hydrolase superfamily
LDP77_22435	COG1321	iron dependent repressor
LDP77_22450	COG0095	Lipoate-protein ligase
LDP77_22455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDP77_22465	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDP77_22470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDP77_22475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LDP77_22505	COG4970	Tfp pilus assembly protein FimT
LDP77_22510	COG4537	Required for transformation and DNA binding
LDP77_22515	COG1459	type II secretion system
LDP77_22520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDP77_22525	COG1393	Belongs to the ArsC family
LDP77_22535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP77_22550	COG1940	carbohydrate kinase activity
LDP77_22555	COG4483	Protein conserved in bacteria
LDP77_22560	COG0457	Tetratricopeptide repeat
LDP77_22560	COG0705	Rhomboid family
LDP77_22575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LDP77_22585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LDP77_22600	COG0704	Plays a role in the regulation of phosphate uptake
LDP77_22610	COG0768	penicillin binding
LDP77_22615	COG0477	Major facilitator Superfamily
LDP77_22650	COG2839	Protein conserved in bacteria
LDP77_22660	COG2814	Major facilitator Superfamily
LDP77_22665	COG1388	LysM domain
LDP77_22670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LDP77_22675	COG4709	membrane
LDP77_22680	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LDP77_22685	COG0735	belongs to the Fur family
LDP77_22690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDP77_22695	COG1121	(ABC) transporter
LDP77_22705	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LDP77_22710	COG0513	Belongs to the DEAD box helicase family
LDP77_22720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LDP77_22725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDP77_22730	COG2384	SAM-dependent methyltransferase
LDP77_22735	COG2010	Cytochrome c
LDP77_22740	COG1960	acyl-CoA dehydrogenase activity
LDP77_22745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDP77_22750	COG0358	DNA primase activity
LDP77_22755	COG1671	Belongs to the UPF0178 family
LDP77_22760	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LDP77_22765	COG0517	IMP dehydrogenase activity
LDP77_22780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LDP77_22785	COG0295	cytidine deaminase activity
LDP77_22790	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LDP77_22800	COG1480	7TM receptor with intracellular HD hydrolase
LDP77_22805	COG1702	phosphate starvation-inducible protein PhoH
LDP77_22830	COG1030	water channel activity
LDP77_22835	COG1610	YqeY-like protein
LDP77_22845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LDP77_22850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LDP77_22855	COG2264	protein methyltransferase activity
LDP77_22870	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LDP77_22875	COG1420	regulation of RNA biosynthetic process
LDP77_22880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LDP77_22885	COG0481	GTPase activity
LDP77_22895	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LDP77_22900	COG0268	Binds directly to 16S ribosomal RNA
LDP77_22905	COG1466	dna polymerase III delta subunit
LDP77_22915	COG0658	competence protein
LDP77_22915	COG2333	competence protein COMEC
LDP77_22920	COG2131	deaminase
LDP77_22925	COG1555	photosystem II stabilization
LDP77_22925	COG1596	polysaccharide export
LDP77_22930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDP77_22935	COG2226	methyltransferase
LDP77_22940	COG0799	negative regulation of ribosome biogenesis
LDP77_22945	COG1713	HD superfamily hydrolase involved in NAD metabolism
LDP77_22950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LDP77_22955	COG1534	Rna-binding protein
LDP77_22960	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDP77_22965	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LDP77_22970	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LDP77_22980	COG0688	phosphatidylethanolamine metabolic process
LDP77_22985	COG1183	phosphatidylcholine synthase activity
LDP77_23010	COG0626	cystathionine gamma-synthase activity
LDP77_23015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LDP77_23020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LDP77_23025	COG2226	methyltransferase
LDP77_23040	COG0768	penicillin binding
LDP77_23045	COG1335	isochorismatase
LDP77_23050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDP77_23055	COG0572	uridine kinase
LDP77_23060	COG0826	peptidase U32
LDP77_23065	COG0826	peptidase U32
LDP77_23070	COG4122	O-methyltransferase activity
LDP77_23075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LDP77_23080	COG3906	Belongs to the UPF0473 family
LDP77_23090	COG4472	Bacterial protein of unknown function (DUF965)
LDP77_23100	COG0628	permease
LDP77_23115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LDP77_23125	COG0482	sulfurtransferase activity
LDP77_23130	COG1104	cysteine desulfurase activity
LDP77_23135	COG1959	2 iron, 2 sulfur cluster binding
LDP77_23140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LDP77_23145	COG0581	inorganic phosphate transmembrane transporter activity
LDP77_23150	COG0573	inorganic phosphate transmembrane transporter activity
LDP77_23155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LDP77_23160	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LDP77_23170	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LDP77_23175	COG0124	histidyl-tRNA synthetase
LDP77_23185	COG0860	N-Acetylmuramoyl-L-alanine amidase
LDP77_23190	COG1490	D-aminoacyl-tRNA deacylase activity
LDP77_23195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDP77_23200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDP77_23205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LDP77_23205	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LDP77_23210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDP77_23210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDP77_23220	COG2244	polysaccharide biosynthetic process
LDP77_23225	COG2323	membrane
LDP77_23235	COG1862	Preprotein translocase
LDP77_23240	COG0343	queuine tRNA-ribosyltransferase activity
LDP77_23245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LDP77_23255	COG2255	four-way junction helicase activity
LDP77_23260	COG0632	four-way junction helicase activity
LDP77_23285	COG1388	LysM domain
LDP77_23290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LDP77_23295	COG0157	Belongs to the NadC ModD family
LDP77_23300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LDP77_23305	COG1104	cysteine desulfurase activity
LDP77_23310	COG1827	regulation of RNA biosynthetic process
LDP77_23315	COG0077	Prephenate dehydratase
LDP77_23320	COG4492	Belongs to the UPF0735 family
LDP77_23325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LDP77_23330	COG3290	protein histidine kinase activity
LDP77_23340	COG2868	ribosomal protein
LDP77_23350	COG1530	ribonuclease E activity
LDP77_23355	COG1994	Peptidase M50
LDP77_23360	COG0739	heme binding
LDP77_23365	COG2894	cell division
LDP77_23370	COG0850	regulation of cytokinetic process
LDP77_23375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LDP77_23380	COG1792	Involved in formation and maintenance of cell shape
LDP77_23385	COG1077	Cell shape determining protein MreB Mrl
LDP77_23390	COG2003	Belongs to the UPF0758 family
LDP77_23395	COG0424	maF-like protein
LDP77_23405	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LDP77_23415	COG2322	membrane
LDP77_23420	COG0285	dihydrofolate synthase activity
LDP77_23425	COG0525	valine-tRNA ligase activity
LDP77_23435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LDP77_23440	COG1388	LysM domain
LDP77_23445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDP77_23450	COG0113	porphobilinogen synthase activity
LDP77_23455	COG1587	Uroporphyrinogen-III synthase
LDP77_23460	COG0181	hydroxymethylbilane synthase activity
LDP77_23465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDP77_23480	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LDP77_23485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LDP77_23490	COG0470	DNA polymerase III
LDP77_23490	COG1067	ATP-dependent peptidase activity
LDP77_23495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LDP77_23500	COG0544	peptidyl-prolyl cis-trans isomerase activity
LDP77_23505	COG0457	Tetratricopeptide repeat
LDP77_23505	COG1477	protein flavinylation
LDP77_23510	COG0066	3-isopropylmalate dehydratase activity
LDP77_23515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LDP77_23525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDP77_23530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LDP77_23535	COG0440	acetolactate synthase activity
LDP77_23540	COG0028	Belongs to the TPP enzyme family
LDP77_23550	COG0622	Phosphoesterase
LDP77_23565	COG5401	PFAM Sporulation and spore germination
LDP77_23570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LDP77_23575	COG1846	Transcriptional regulator
LDP77_23585	COG0306	phosphate transporter
LDP77_23590	COG1392	Phosphate transport regulator
LDP77_23595	COG0768	penicillin binding
LDP77_23600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP77_23605	COG0431	NADPH-dependent FMN reductase
LDP77_23610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDP77_23615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LDP77_23620	COG1116	anion transmembrane transporter activity
LDP77_23625	COG0475	glutathione-regulated potassium exporter activity
LDP77_23630	COG0490	domain, Protein
LDP77_23640	COG2197	response regulator
LDP77_23645	COG0824	Thioesterase
LDP77_23650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LDP77_23655	COG1053	succinate dehydrogenase
LDP77_23660	COG2009	succinate dehydrogenase
LDP77_23665	COG1719	4-vinyl reductase, 4VR
LDP77_23670	COG0527	aspartate kinase activity
LDP77_23680	COG3118	belongs to the thioredoxin family
LDP77_23685	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LDP77_23690	COG2086	electron transfer activity
LDP77_23695	COG1024	Enoyl-CoA hydratase
LDP77_23700	COG1309	transcriptional regulator
LDP77_23705	COG0318	PFAM AMP-dependent synthetase and ligase
LDP77_23710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LDP77_23715	COG3766	membrane
LDP77_23720	COG1193	negative regulation of DNA recombination
LDP77_23725	COG1796	DNA polymerase
LDP77_23725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LDP77_23730	COG1286	toxin biosynthetic process
LDP77_23735	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LDP77_23745	COG0072	phenylalanine-tRNA ligase activity
LDP77_23745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDP77_23750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LDP77_23755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDP77_23765	COG1363	Peptidase, m42
LDP77_23785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LDP77_23790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LDP77_23795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LDP77_23800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LDP77_23810	COG1484	DNA-dependent DNA replication
LDP77_23815	COG3611	Membrane attachment protein
LDP77_23820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LDP77_23830	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LDP77_23835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDP77_23840	COG0237	dephospho-CoA kinase activity
LDP77_23845	COG1971	Probably functions as a manganese efflux pump
LDP77_23850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDP77_23855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDP77_23855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDP77_23860	COG5002	protein histidine kinase activity
LDP77_23865	COG0745	RESPONSE REGULATOR receiver
LDP77_23875	COG0039	L-malate dehydrogenase activity
LDP77_23880	COG0538	isocitrate dehydrogenase activity
LDP77_23885	COG0372	Belongs to the citrate synthase family
LDP77_23890	COG2707	UPF0756 membrane protein
LDP77_23895	COG0628	permease
LDP77_23900	COG3030	protein affecting phage T7 exclusion by the F plasmid
LDP77_23910	COG0825	malonyl-CoA metabolic process
LDP77_23915	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LDP77_23920	COG2186	Transcriptional regulator
LDP77_23925	COG0281	malic enzyme
LDP77_23930	COG0587	DNA-directed DNA polymerase activity
LDP77_23945	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LDP77_23955	COG4109	DRTGG domain
LDP77_23970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LDP77_23985	COG0165	Argininosuccinate lyase
LDP77_23990	COG0137	argininosuccinate synthase activity
LDP77_24005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LDP77_24010	COG0827	DNA restriction-modification system
LDP77_24015	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LDP77_24020	COG3874	Sporulation protein YtfJ
LDP77_24030	COG1714	RDD family
LDP77_24035	COG0616	signal peptide processing
LDP77_24040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LDP77_24045	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LDP77_24055	COG0301	tRNA thio-modification
LDP77_24060	COG1104	cysteine desulfurase activity
LDP77_24065	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LDP77_24070	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LDP77_24075	COG1309	transcriptional regulator
LDP77_24080	COG1956	GAF domain-containing protein
LDP77_24095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDP77_24100	COG0454	-acetyltransferase
LDP77_24105	COG0517	IMP dehydrogenase activity
LDP77_24110	COG0123	including yeast histone deacetylase and acetoin utilization protein
LDP77_24130	COG1605	Chorismate mutase
LDP77_24130	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LDP77_24135	COG3118	belongs to the thioredoxin family
LDP77_24140	COG4980	gas vesicle protein
LDP77_24155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LDP77_24165	COG1674	ftsk spoiiie
LDP77_24170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDP77_24175	COG4848	Belongs to the UPF0354 family
LDP77_24180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDP77_24185	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LDP77_24190	COG1363	Peptidase, m42
LDP77_24195	COG5584	Small secreted protein
LDP77_24200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP77_24205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LDP77_24215	COG0510	thiamine kinase activity
LDP77_24220	COG1523	belongs to the glycosyl hydrolase 13 family
LDP77_24230	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LDP77_24235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LDP77_24240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDP77_24245	COG1349	DNA-binding transcription factor activity
LDP77_24250	COG1187	pseudouridine synthase activity
LDP77_24255	COG2244	polysaccharide biosynthetic process
LDP77_24260	COG2081	HI0933 family
LDP77_24270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDP77_24275	COG0495	leucyl-tRNA aminoacylation
LDP77_24285	COG2610	gluconate transmembrane transporter activity
LDP77_24290	COG2814	Major facilitator Superfamily
LDP77_24305	COG1242	4 iron, 4 sulfur cluster binding
LDP77_24310	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LDP77_24320	COG2267	carboxylic ester hydrolase activity
LDP77_24325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LDP77_24330	COG0671	phosphoesterase, PA-phosphatase related
LDP77_24335	COG0438	transferase activity, transferring glycosyl groups
LDP77_24340	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LDP77_24345	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LDP77_24355	COG1506	peptidase
LDP77_24360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LDP77_24365	COG1116	anion transmembrane transporter activity
LDP77_24370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDP77_24375	COG0494	nUDIX hydrolase
LDP77_24385	COG4824	toxin secretion phage lysis holin
LDP77_24390	COG0783	Belongs to the Dps family
LDP77_24400	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LDP77_24405	COG0288	reversible hydration of carbon dioxide
LDP77_24410	COG0523	cobalamin synthesis protein
LDP77_24420	COG0254	rRNA binding
LDP77_24425	COG1271	oxidase subunit
LDP77_24430	COG1294	oxidase, subunit
LDP77_24435	COG0716	FMN binding
LDP77_24460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDP77_24465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDP77_24470	COG4948	Mandelate Racemase Muconate Lactonizing
LDP77_24475	COG0318	PFAM AMP-dependent synthetase and ligase
LDP77_24480	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LDP77_24485	COG0596	Alpha beta hydrolase
LDP77_24490	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LDP77_24495	COG1169	isochorismate synthase
LDP77_24500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LDP77_24510	COG0058	SHG alpha-glucan phosphorylase activity
LDP77_24515	COG0297	glycogen (starch) synthase activity
LDP77_24520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LDP77_24525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LDP77_24655	COG0318	PFAM AMP-dependent synthetase and ligase
LDP77_24660	COG1285	pathogenesis
LDP77_24680	COG0529	Catalyzes the synthesis of activated sulfate
LDP77_24690	COG0306	phosphate transporter
LDP77_24700	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LDP77_24705	COG0346	lactoylglutathione lyase activity
LDP77_24710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LDP77_24720	COG0166	Belongs to the GPI family
LDP77_24730	COG2111	Na H antiporter
LDP77_24730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LDP77_24735	COG2111	Na H antiporter
LDP77_24740	COG1006	Multisubunit Na H antiporter MnhC subunit
LDP77_24745	COG0651	ATP synthesis coupled electron transport
LDP77_24750	COG1863	multisubunit Na H antiporter MnhE subunit
LDP77_24755	COG2212	antiporter activity
LDP77_24760	COG1320	monovalent cation:proton antiporter activity
LDP77_24765	COG1979	alcohol dehydrogenase
LDP77_24770	COG2155	Conserved Protein
LDP77_24775	COG1098	S1 RNA binding domain
LDP77_24780	COG0436	Aminotransferase
LDP77_24785	COG1522	sequence-specific DNA binding
LDP77_24790	COG2267	carboxylic ester hydrolase activity
LDP77_24795	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LDP77_24800	COG2032	superoxide dismutase activity
LDP77_24815	COG5018	Exonuclease
LDP77_24820	COG2050	protein possibly involved in aromatic compounds catabolism
LDP77_24830	COG1418	mRNA catabolic process
LDP77_24840	COG2056	Na+-H+ antiporter family
LDP77_24845	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LDP77_24850	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LDP77_24855	COG3584	3D domain protein
LDP77_24865	COG1252	NADH dehydrogenase
LDP77_24870	COG0492	ferredoxin-NADP+ reductase activity
LDP77_24880	COG0316	Belongs to the HesB IscA family
LDP77_24885	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LDP77_24890	COG4844	belongs to the
LDP77_24895	COG1252	NADH dehydrogenase
LDP77_24900	COG4837	Protein of unknown function (DUF1462)
LDP77_24905	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LDP77_24910	COG0083	homoserine kinase activity
LDP77_24915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LDP77_24920	COG0460	homoserine dehydrogenase
LDP77_24925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDP77_24930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LDP77_24935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LDP77_24940	COG0647	UMP catabolic process
LDP77_24945	COG2445	Protein of unknown function DUF86
LDP77_24955	COG4470	Protein conserved in bacteria
LDP77_24965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LDP77_24970	COG0739	heme binding
LDP77_24980	COG0733	neurotransmitter:sodium symporter activity
LDP77_24990	COG3377	Domain of unknown function (DUF1805)
LDP77_24995	COG1801	Protein of unknown function DUF72
LDP77_25000	COG0719	Fe-S assembly protein
LDP77_25005	COG0822	iron-sulfur transferase activity
LDP77_25010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDP77_25015	COG0719	Fe-S assembly protein
LDP77_25020	COG0396	ATPase activity
LDP77_25025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LDP77_25030	COG1464	Belongs to the NlpA lipoprotein family
LDP77_25035	COG2011	ABC-type metal ion transport system permease component
LDP77_25040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LDP77_25045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDP77_25050	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LDP77_25060	COG0509	glycine decarboxylation via glycine cleavage system
LDP77_25065	COG1393	Belongs to the ArsC family
LDP77_25070	COG1960	acyl-CoA dehydrogenase activity
LDP77_25075	COG0183	Belongs to the thiolase family
LDP77_25080	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDP77_25080	COG1024	Enoyl-CoA hydratase
LDP77_25105	COG1120	ATPase activity
LDP77_25110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP77_25115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP77_25120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDP77_25135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDP77_25140	COG1309	transcriptional regulator
LDP77_25150	COG1028	Short-chain dehydrogenase reductase Sdr
LDP77_25155	COG0477	Major facilitator Superfamily
LDP77_25165	COG3850	Histidine kinase
LDP77_25165	COG5002	protein histidine kinase activity
LDP77_25170	COG0745	RESPONSE REGULATOR receiver
LDP77_25175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LDP77_25180	COG0671	phosphoesterase, PA-phosphatase related
LDP77_25190	COG1846	Transcriptional regulator
LDP77_25195	COG0778	Nitroreductase
LDP77_25200	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LDP77_25205	COG0314	molybdopterin synthase activity
LDP77_25210	COG1763	Mo-molybdopterin cofactor biosynthetic process
LDP77_25215	COG0303	'Molybdopterin
LDP77_25220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LDP77_25225	COG0746	molybdenum cofactor guanylyltransferase activity
LDP77_25235	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDP77_25240	COG5609	conserved protein (DUF2294)
LDP77_25245	COG3383	formate dehydrogenase (NAD+) activity
LDP77_25250	COG2427	Protein of unknown function (DUF1641)
LDP77_25255	COG0725	ABC transporter, periplasmic molybdate-binding protein
LDP77_25260	COG4149	molybdate abc transporter
LDP77_25270	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LDP77_25275	COG0557	exoribonuclease II activity
LDP77_25280	COG1647	Serine aminopeptidase, S33
LDP77_25285	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDP77_25295	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LDP77_25325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LDP77_25345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP77_25355	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LDP77_25360	COG1660	Displays ATPase and GTPase activities
LDP77_25365	COG1051	belongs to the nudix hydrolase family
LDP77_25370	COG0492	ferredoxin-NADP+ reductase activity
LDP77_25375	COG0457	Tetratricopeptide repeat
LDP77_25380	COG0140	phosphoribosyl-ATP diphosphatase activity
LDP77_25380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LDP77_25385	COG0107	imidazoleglycerol-phosphate synthase activity
LDP77_25390	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LDP77_25395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LDP77_25400	COG0131	Imidazoleglycerol-phosphate dehydratase
LDP77_25405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDP77_25410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LDP77_25415	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LDP77_25420	COG0110	maltose O-acetyltransferase activity
LDP77_25425	COG0546	phosphoglycolate phosphatase activity
LDP77_25430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LDP77_25435	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LDP77_25440	COG1950	PFAM Membrane protein of
LDP77_25445	COG1983	PspC domain protein
LDP77_25450	COG3595	metallopeptidase activity
LDP77_25460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDP77_25465	COG0556	nucleotide-excision repair
LDP77_25470	COG2204	response regulator
LDP77_25475	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_25480	COG0506	proline dehydrogenase activity
LDP77_25485	COG4897	Protein conserved in bacteria
LDP77_25490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDP77_25495	COG0793	Belongs to the peptidase S41A family
LDP77_25495	COG3409	Peptidoglycan-binding domain 1 protein
LDP77_25500	COG0739	heme binding
LDP77_25505	COG2177	Part of the ABC transporter FtsEX involved in
LDP77_25510	COG2884	Cell division ATP-binding protein ftsE
LDP77_25515	COG0655	NAD(P)H dehydrogenase (quinone) activity
LDP77_25525	COG0805	protein transport
LDP77_25530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDP77_25535	COG3540	Alkaline phosphatase
LDP77_25545	COG0653	protein targeting
LDP77_25550	COG0456	acetyltransferase
LDP77_25555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LDP77_25565	COG1516	flagellar protein fliS
LDP77_25570	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LDP77_25580	COG1113	amino acid transport
LDP77_25590	COG1012	belongs to the aldehyde dehydrogenase family
LDP77_25595	COG1454	alcohol dehydrogenase
LDP77_25600	COG1510	regulation of RNA biosynthetic process
LDP77_25605	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LDP77_25610	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LDP77_25615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDP77_25620	COG4786	Flagellar basal body rod
LDP77_25620	COG1256	bacterial-type flagellum assembly
LDP77_25640	COG1040	competence protein
LDP77_25645	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LDP77_25650	COG1307	EDD domain protein, DegV family
LDP77_25655	COG1728	Protein conserved in bacteria
LDP77_25665	COG2197	response regulator
LDP77_25670	COG4585	Histidine kinase
LDP77_25675	COG1739	Uncharacterized protein family UPF0029
LDP77_25680	COG1316	TRANSCRIPTIONal
LDP77_25685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDP77_25690	COG1585	Membrane protein implicated in regulation of membrane protease activity
LDP77_25695	COG2268	Band 7 protein
LDP77_25700	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LDP77_25710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LDP77_25720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LDP77_25725	COG1388	LysM domain
LDP77_25725	COG0791	NLP P60 protein
LDP77_25730	COG0629	single-stranded DNA binding
LDP77_25750	COG4786	Flagellar basal body rod
LDP77_25755	COG4786	Flagellar basal body rod
LDP77_25760	COG1077	Cell shape determining protein MreB Mrl
LDP77_25765	COG1609	Transcriptional regulator
LDP77_25770	COG0739	heme binding
LDP77_25775	COG2385	sporulation resulting in formation of a cellular spore
LDP77_25790	COG4836	Membrane
LDP77_25795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LDP77_25800	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LDP77_25805	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LDP77_25810	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LDP77_25815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDP77_25820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LDP77_25825	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDP77_25830	COG0356	it plays a direct role in the translocation of protons across the membrane
LDP77_25845	COG1404	Belongs to the peptidase S8 family
LDP77_25850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LDP77_25855	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LDP77_25870	COG0698	ribose 5-phosphate isomerase
LDP77_25880	COG1971	Probably functions as a manganese efflux pump
LDP77_25885	COG0009	L-threonylcarbamoyladenylate synthase
LDP77_25905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LDP77_25920	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LDP77_25930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LDP77_25935	COG0191	fructose-bisphosphate aldolase activity
LDP77_25940	COG2204	response regulator
LDP77_25945	COG4821	SIS domain
LDP77_25950	COG0504	CTP synthase activity
LDP77_25960	COG1703	isobutyryl-CoA mutase activity
LDP77_25960	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDP77_25960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDP77_25970	COG1960	acyl-CoA dehydrogenase activity
LDP77_25975	COG1960	acyl-CoA dehydrogenase activity
LDP77_25980	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDP77_25985	COG0183	Belongs to the thiolase family
LDP77_25990	COG2181	nitrate reductase activity
LDP77_25990	COG0247	lactate metabolic process
LDP77_25995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDP77_26005	COG0018	arginyl-trna synthetase
LDP77_26010	COG4506	Protein conserved in bacteria
LDP77_26015	COG0010	Belongs to the arginase family
LDP77_26020	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LDP77_26025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDP77_26035	COG1994	Peptidase M50
LDP77_26040	COG1942	4-Oxalocrotonate Tautomerase
LDP77_26045	COG3465	dGTPase activity
LDP77_26050	COG1078	dGTPase activity
LDP77_26055	COG4844	belongs to the
LDP77_26065	COG0095	Lipoate-protein ligase
LDP77_26070	COG0280	phosphate acetyltransferase
LDP77_26075	COG3253	May function as heme-dependent peroxidase
LDP77_26080	COG3773	Cell wall hydrolase
LDP77_26090	COG2363	Small membrane protein
LDP77_26100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LDP77_26110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LDP77_26115	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LDP77_26120	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LDP77_26120	COG2508	Transcriptional regulator
LDP77_26125	COG0686	Belongs to the AlaDH PNT family
LDP77_26135	COG0351	phosphomethylpyrimidine kinase
LDP77_26140	COG0561	phosphatase activity
LDP77_26145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDP77_26150	COG2190	(PTS) system
LDP77_26150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP77_26150	COG1263	PTS System
LDP77_26160	COG0438	transferase activity, transferring glycosyl groups
LDP77_26175	COG2076	Multidrug Resistance protein
LDP77_26185	COG0728	peptidoglycan biosynthetic process
LDP77_26200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LDP77_26205	COG4988	ABC transporter
LDP77_26210	COG1294	oxidase, subunit
LDP77_26215	COG1271	oxidase subunit
LDP77_26220	COG3610	response to peptide
LDP77_26225	COG2966	Psort location CytoplasmicMembrane, score
LDP77_26230	COG1609	Transcriptional regulator
LDP77_26240	COG2814	Major facilitator Superfamily
LDP77_26255	COG1966	Carbon starvation protein
LDP77_26260	COG0753	catalase activity
LDP77_26275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LDP77_26285	COG0745	RESPONSE REGULATOR receiver
LDP77_26290	COG5002	protein histidine kinase activity
LDP77_26305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LDP77_26310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LDP77_26320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDP77_26325	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LDP77_26330	COG4853	Protein conserved in bacteria
LDP77_26340	COG5002	protein histidine kinase activity
LDP77_26345	COG0745	RESPONSE REGULATOR receiver
LDP77_26370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LDP77_26375	COG0305	Participates in initiation and elongation during chromosome replication
LDP77_26385	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LDP77_26395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LDP77_26405	COG0360	Binds together with S18 to 16S ribosomal RNA
LDP77_26410	COG0012	GTP binding
LDP77_26415	COG4481	Protein conserved in bacteria
LDP77_26420	COG0668	transmembrane transport
LDP77_26425	COG3949	Membrane
LDP77_26435	COG1475	DNA binding
LDP77_26440	COG1192	Involved in chromosome partitioning
LDP77_26445	COG1475	DNA binding
LDP77_26455	COG0445	tRNA wobble uridine modification
LDP77_26460	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LDP77_26465	COG1847	R3H domain protein
LDP77_26470	COG0706	membrane insertase activity
LDP77_26475	COG0594	ribonuclease P activity
LDP77_26480	COG0230	Belongs to the bacterial ribosomal protein bL34 family