locus-tag	class	description
I7V34_00010	COG3290	protein histidine kinase activity
I7V34_00015	COG3279	Response regulator of the LytR AlgR family
I7V34_00020	COG4555	ABC transporter
I7V34_00025	COG1668	transmembrane transport
I7V34_00035	COG2311	Membrane
I7V34_00045	COG1278	Cold shock
I7V34_00055	COG1278	Cold shock
I7V34_00060	COG0745	RESPONSE REGULATOR receiver
I7V34_00065	COG3850	Histidine kinase
I7V34_00065	COG5002	protein histidine kinase activity
I7V34_00070	COG0577	efflux transmembrane transporter activity
I7V34_00075	COG1136	(ABC) transporter
I7V34_00080	COG3682	Transcriptional regulator
I7V34_00090	COG2217	Heavy metal translocating P-type atpase
I7V34_00120	COG0366	Alpha amylase catalytic
I7V34_00125	COG0395	ABC-type sugar transport system, permease component
I7V34_00135	COG2182	Extracellular solute-binding protein
I7V34_00145	COG3459	Glycosyltransferase 36 associated
I7V34_00150	COG3663	DNA glycosylase
I7V34_00170	COG0438	transferase activity, transferring glycosyl groups
I7V34_00180	COG0463	Glycosyl transferase, family 2
I7V34_00210	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_00215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I7V34_00225	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_00230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I7V34_00235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I7V34_00250	COG2346	COG2346, Truncated hemoglobins
I7V34_00255	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
I7V34_00260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I7V34_00265	COG0535	radical SAM domain protein
I7V34_00275	COG0489	protein tyrosine kinase activity
I7V34_00285	COG0243	molybdopterin cofactor binding
I7V34_00290	COG0437	4 iron, 4 sulfur cluster binding
I7V34_00295	COG4638	Rieske (2fe-2S)
I7V34_00310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I7V34_00315	COG0303	'Molybdopterin
I7V34_00320	COG0314	molybdopterin synthase activity
I7V34_00335	COG0521	Mo-molybdopterin cofactor biosynthetic process
I7V34_00340	COG0725	ABC transporter, periplasmic molybdate-binding protein
I7V34_00345	COG4149	molybdate abc transporter
I7V34_00360	COG2223	nitrite transmembrane transporter activity
I7V34_00370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I7V34_00375	COG0746	molybdenum cofactor guanylyltransferase activity
I7V34_00380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
I7V34_00390	COG1657	PFAM Prenyltransferase squalene oxidase
I7V34_00410	COG1115	amino acid carrier protein
I7V34_00415	COG3152	Membrane
I7V34_00425	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_00435	COG1454	alcohol dehydrogenase
I7V34_00440	COG3829	transcription factor binding
I7V34_00440	COG3290	protein histidine kinase activity
I7V34_00455	COG3832	glyoxalase III activity
I7V34_00505	COG2207	Transcriptional regulator
I7V34_00505	COG3708	Transcriptional regulator
I7V34_00515	COG2186	Transcriptional regulator
I7V34_00520	COG1620	l-lactate permease
I7V34_00525	COG0247	lactate metabolic process
I7V34_00530	COG1139	Iron-sulfur cluster binding protein
I7V34_00535	COG1556	Lactate utilization protein
I7V34_00560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
I7V34_00580	COG2205	protein histidine kinase activity
I7V34_00585	COG0778	Nitroreductase
I7V34_00600	COG1268	BioY protein
I7V34_00605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
I7V34_00610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I7V34_00615	COG0247	lactate metabolic process
I7V34_00620	COG0277	FAD linked oxidase domain protein
I7V34_00635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_00635	COG1263	PTS System
I7V34_00640	COG2188	Transcriptional regulator
I7V34_00645	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I7V34_00650	COG0363	glucosamine-6-phosphate deaminase activity
I7V34_00655	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
I7V34_00660	COG0069	glutamate synthase activity
I7V34_00660	COG0067	glutamate synthase
I7V34_00660	COG0070	glutamate synthase
I7V34_00665	COG0493	'glutamate synthase
I7V34_00670	COG1263	PTS System
I7V34_00670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_00680	COG1595	DNA-templated transcription, initiation
I7V34_00695	COG3290	protein histidine kinase activity
I7V34_00700	COG4565	transcriptional regulatory protein
I7V34_00705	COG3181	Tripartite tricarboxylate transporter family receptor
I7V34_00720	COG1053	succinate dehydrogenase
I7V34_00730	COG1607	acyl-coa hydrolase
I7V34_00735	COG2268	Band 7 protein
I7V34_00750	COG0737	Belongs to the 5'-nucleotidase family
I7V34_00760	COG1073	alpha beta
I7V34_00770	COG0277	FAD linked oxidase domain protein
I7V34_00775	COG0385	Bile acid
I7V34_00780	COG2031	fatty acid transporter
I7V34_00785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I7V34_00790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I7V34_00795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I7V34_00800	COG1120	ATPase activity
I7V34_00805	COG0492	ferredoxin-NADP+ reductase activity
I7V34_00810	COG0861	Integral membrane protein TerC family
I7V34_00820	COG2832	Protein of unknown function (DUF454)
I7V34_00835	COG0697	spore germination
I7V34_00850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
I7V34_00855	COG2270	Major facilitator Superfamily
I7V34_00870	COG0586	Pfam SNARE associated Golgi protein
I7V34_00875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I7V34_00880	COG1664	Polymer-forming cytoskeletal
I7V34_00885	COG0789	Transcriptional regulator
I7V34_00895	COG0753	catalase activity
I7V34_00910	COG0542	response to heat
I7V34_00915	COG0561	phosphatase activity
I7V34_00925	COG3706	GGDEF domain
I7V34_00955	COG1090	epimerase
I7V34_00990	COG1988	membrane-bound metal-dependent
I7V34_01000	COG1194	a g-specific adenine glycosylase
I7V34_01010	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_01025	COG3557	Belongs to the UPF0374 family
I7V34_01030	COG1132	(ABC) transporter
I7V34_01035	COG0444	Belongs to the ABC transporter superfamily
I7V34_01040	COG4608	Belongs to the ABC transporter superfamily
I7V34_01045	COG0747	negative chemotaxis
I7V34_01050	COG0601	transmembrane transport
I7V34_01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I7V34_01060	COG4129	membrane
I7V34_01065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
I7V34_01075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I7V34_01080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I7V34_01085	COG2096	Adenosyltransferase
I7V34_01090	COG0735	belongs to the Fur family
I7V34_01215	COG2972	Histidine kinase
I7V34_01230	COG0673	inositol 2-dehydrogenase activity
I7V34_01235	COG0673	inositol 2-dehydrogenase activity
I7V34_01240	COG1082	Xylose isomerase domain protein TIM barrel
I7V34_01245	COG3382	B3 4 domain protein
I7V34_01250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
I7V34_01260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I7V34_01265	COG0778	Nitroreductase
I7V34_01270	COG2766	serine protein kinase
I7V34_01285	COG2718	Belongs to the UPF0229 family
I7V34_01300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I7V34_01310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I7V34_01345	COG2252	PERMEase
I7V34_01350	COG4187	Peptidase family M20/M25/M40
I7V34_01355	COG0778	Nitroreductase
I7V34_01360	COG1609	Transcriptional regulator
I7V34_01365	COG1970	mechanosensitive ion channel activity
I7V34_01375	COG3973	AAA domain
I7V34_01390	COG0656	L-ascorbic acid biosynthetic process
I7V34_01395	COG0655	NAD(P)H dehydrogenase (quinone) activity
I7V34_01400	COG0564	pseudouridine synthase activity
I7V34_01410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_01415	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
I7V34_01420	COG3153	acetyltransferase
I7V34_01420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I7V34_01425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I7V34_01430	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_01435	COG2203	Gaf domain
I7V34_01435	COG4585	Histidine kinase
I7V34_01440	COG2197	response regulator
I7V34_01445	COG0431	NADPH-dependent FMN reductase
I7V34_01460	COG2211	Major facilitator Superfamily
I7V34_01465	COG2719	SpoVR family
I7V34_01475	COG2364	Membrane
I7V34_01480	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_01485	COG2610	gluconate transmembrane transporter activity
I7V34_01500	COG4989	oxidoreductase activity
I7V34_01515	COG1533	DNA photolyase activity
I7V34_01525	COG1301	dicarboxylic acid transport
I7V34_01545	COG2814	Major facilitator Superfamily
I7V34_01550	COG1595	DNA-templated transcription, initiation
I7V34_01565	COG0393	Putative heavy-metal-binding
I7V34_01570	COG1132	(ABC) transporter
I7V34_01575	COG1132	(ABC) transporter
I7V34_01585	COG0702	epimerase
I7V34_01590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I7V34_01595	COG0765	amino acid transport
I7V34_01600	COG1126	abc transporter atp-binding protein
I7V34_01630	COG3842	ATPase activity
I7V34_01635	COG2508	Transcriptional regulator
I7V34_01640	COG1937	Protein conserved in bacteria
I7V34_01665	COG0189	ligase activity
I7V34_01670	COG0189	ligase activity
I7V34_01675	COG0189	ligase activity
I7V34_01680	COG4399	Belongs to the UPF0754 family
I7V34_01685	COG3679	Belongs to the UPF0342 family
I7V34_01690	COG0561	phosphatase activity
I7V34_01695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I7V34_01700	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_01705	COG1024	Enoyl-CoA hydratase
I7V34_01720	COG4152	abc transporter atp-binding protein
I7V34_01725	COG1668	transmembrane transport
I7V34_01730	COG0420	3'-5' exonuclease activity
I7V34_01735	COG4717	serine-type aminopeptidase activity
I7V34_01740	COG3481	metal-dependent phosphohydrolase, HD sub domain
I7V34_01750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I7V34_01775	COG1846	Transcriptional regulator
I7V34_01795	COG0537	adenosine 5'-monophosphoramidase activity
I7V34_01800	COG1131	(ABC) transporter
I7V34_01805	COG4473	ABC transporter
I7V34_01815	COG1473	amidohydrolase
I7V34_01825	COG3069	C4-dicarboxylate transmembrane transporter activity
I7V34_01835	COG4585	Histidine kinase
I7V34_01840	COG2197	response regulator
I7V34_01845	COG2329	Antibiotic biosynthesis monooxygenase
I7V34_01850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
I7V34_01855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
I7V34_01860	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
I7V34_01870	COG1309	transcriptional regulator
I7V34_01875	COG1511	domain protein
I7V34_01890	COG1234	tRNA 3'-trailer cleavage
I7V34_01895	COG0095	Lipoate-protein ligase
I7V34_01905	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_01910	COG1024	Enoyl-CoA hydratase
I7V34_01920	COG2391	methyltransferase activity
I7V34_01925	COG1396	sequence-specific DNA binding
I7V34_01930	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
I7V34_01940	COG0501	Belongs to the peptidase M48B family
I7V34_01945	COG2323	membrane
I7V34_01955	COG4903	ComK protein
I7V34_01965	COG0823	Involved in the tonB-independent uptake of proteins
I7V34_01965	COG1506	peptidase
I7V34_01965	COG4946	Tricorn protease homolog
I7V34_01970	COG0398	Pfam SNARE associated Golgi protein
I7V34_01980	COG2909	trisaccharide binding
I7V34_02010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I7V34_02020	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_02025	COG0183	Belongs to the thiolase family
I7V34_02030	COG2356	endonuclease I
I7V34_02035	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_02045	COG2814	Major facilitator Superfamily
I7V34_02050	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
I7V34_02055	COG1074	ATP-dependent DNA helicase activity
I7V34_02060	COG1403	HNH endonuclease
I7V34_02095	COG2311	Membrane
I7V34_02100	COG0179	Fumarylacetoacetate (FAA) hydrolase
I7V34_02120	COG0367	asparagine synthase
I7V34_02125	COG0004	ammonium transporteR
I7V34_02130	COG0347	Belongs to the P(II) protein family
I7V34_02135	COG0534	Mate efflux family protein
I7V34_02145	COG2182	Extracellular solute-binding protein
I7V34_02150	COG1175	transmembrane transport
I7V34_02155	COG3833	ABC-type maltose transport systems, permease component
I7V34_02165	COG1609	Transcriptional regulator
I7V34_02170	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_02175	COG0446	pyridine nucleotide-disulphide oxidoreductase
I7V34_02180	COG1666	GTP binding
I7V34_02190	COG1307	EDD domain protein, DegV family
I7V34_02195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_02210	COG0561	phosphatase activity
I7V34_02215	COG1073	alpha beta
I7V34_02220	COG2151	metal-sulfur cluster biosynthetic enzyme
I7V34_02245	COG2267	carboxylic ester hydrolase activity
I7V34_02255	COG1744	ABC transporter substrate-binding protein PnrA-like
I7V34_02265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I7V34_02270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I7V34_02275	COG5504	Zn-dependent protease
I7V34_02290	COG0180	Tryptophanyl-tRNA synthetase
I7V34_02300	COG4166	transmembrane transport
I7V34_02305	COG0601	transmembrane transport
I7V34_02310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I7V34_02315	COG0444	Belongs to the ABC transporter superfamily
I7V34_02320	COG4608	Belongs to the ABC transporter superfamily
I7V34_02330	COG0456	acetyltransferase
I7V34_02335	COG1393	Belongs to the ArsC family
I7V34_02340	COG4862	establishment of competence for transformation
I7V34_02345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I7V34_02355	COG1164	Oligoendopeptidase f
I7V34_02365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
I7V34_02370	COG2346	COG2346, Truncated hemoglobins
I7V34_02375	COG0741	lytic transglycosylase activity
I7V34_02380	COG4116	CYTH
I7V34_02390	COG2357	RelA SpoT domain protein
I7V34_02400	COG0564	pseudouridine synthase activity
I7V34_02405	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
I7V34_02410	COG2239	Acts as a magnesium transporter
I7V34_02415	COG0569	domain protein
I7V34_02415	COG0475	glutathione-regulated potassium exporter activity
I7V34_02455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I7V34_02465	COG2323	membrane
I7V34_02485	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I7V34_02490	COG2323	membrane
I7V34_02495	COG2153	protein acetylation
I7V34_02500	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
I7V34_02505	COG2382	esterase
I7V34_02510	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I7V34_02515	COG2358	TRAP transporter, solute receptor (TAXI family
I7V34_02555	COG1960	acyl-CoA dehydrogenase activity
I7V34_02560	COG0183	Belongs to the thiolase family
I7V34_02565	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
I7V34_02580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I7V34_02585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I7V34_02595	COG1764	response to oxidative stress
I7V34_02605	COG1295	ribonuclease BN
I7V34_02610	COG3104	oligopeptide transport
I7V34_02615	COG1363	Peptidase, m42
I7V34_02620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
I7V34_02625	COG3706	GGDEF domain
I7V34_02630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I7V34_02640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
I7V34_02645	COG3300	MHYT domain
I7V34_02645	COG5001	Diguanylate cyclase
I7V34_02650	COG1757	Na H antiporter
I7V34_02670	COG0861	Integral membrane protein TerC family
I7V34_02680	COG1191	sigma factor activity
I7V34_02695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I7V34_02715	COG3594	Acyltransferase
I7V34_02720	COG5002	protein histidine kinase activity
I7V34_02725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I7V34_02730	COG0640	Transcriptional regulator
I7V34_02735	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
I7V34_02740	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
I7V34_02745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I7V34_02750	COG0436	Aminotransferase
I7V34_02755	COG1850	ribulose-bisphosphate carboxylase activity
I7V34_02760	COG0235	Class ii aldolase
I7V34_02780	COG1846	Transcriptional regulator
I7V34_02790	COG3949	Membrane
I7V34_02800	COG4873	Protein conserved in bacteria
I7V34_02810	COG3773	Cell wall hydrolase
I7V34_02815	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_02820	COG0714	Associated with various cellular activities
I7V34_02835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I7V34_02840	COG0390	transport system, permease component
I7V34_02855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I7V34_02860	COG0456	acetyltransferase
I7V34_02870	COG0436	Aminotransferase
I7V34_02875	COG0598	Magnesium transport protein CorA
I7V34_02885	COG0720	synthase
I7V34_02890	COG0602	queuosine metabolic process
I7V34_02900	COG0835	chemotaxis
I7V34_02900	COG0784	Response regulator, receiver
I7V34_02915	COG5001	Diguanylate cyclase
I7V34_02915	COG3300	MHYT domain
I7V34_02925	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_02930	COG2200	EAL domain
I7V34_02950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_02955	COG4703	Protein of unknown function (DUF1797)
I7V34_02960	COG0517	IMP dehydrogenase activity
I7V34_02965	COG0477	Major facilitator Superfamily
I7V34_02975	COG0583	DNA-binding transcription factor activity
I7V34_02985	COG1473	amidohydrolase
I7V34_02990	COG0668	transmembrane transport
I7V34_02995	COG1132	(ABC) transporter
I7V34_03000	COG1132	(ABC) transporter
I7V34_03010	COG1271	oxidase subunit
I7V34_03015	COG1294	oxidase, subunit
I7V34_03020	COG0569	domain protein
I7V34_03025	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
I7V34_03035	COG0561	phosphatase activity
I7V34_03040	COG0242	peptide deformylase activity
I7V34_03055	COG0022	dehydrogenase e1 component
I7V34_03060	COG0508	dehydrogenase complex catalyzes the overall conversion of
I7V34_03070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_03075	COG0726	polysaccharide deacetylase
I7V34_03085	COG1982	Orn Lys Arg decarboxylase major
I7V34_03095	COG4476	Belongs to the UPF0223 family
I7V34_03100	COG4493	Belongs to the UPF0637 family
I7V34_03110	COG0483	inositol monophosphate 1-phosphatase activity
I7V34_03120	COG1217	gtp-binding protein TYPA
I7V34_03135	COG4896	Protein conserved in bacteria
I7V34_03150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
I7V34_03155	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
I7V34_03160	COG2066	Belongs to the glutaminase family
I7V34_03170	COG0772	Belongs to the SEDS family
I7V34_03175	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
I7V34_03200	COG1845	cytochrome c oxidase, subunit III
I7V34_03225	COG3336	cytochrome c oxidase
I7V34_03240	COG0628	permease
I7V34_03250	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
I7V34_03255	COG2340	Cysteine-rich secretory protein family
I7V34_03280	COG3679	Belongs to the UPF0342 family
I7V34_03300	COG0742	ribosomal rna small subunit methyltransferase
I7V34_03305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
I7V34_03310	COG3314	Sporulation integral membrane protein YlbJ
I7V34_03315	COG1752	Esterase of the alpha-beta hydrolase superfamily
I7V34_03320	COG3480	Lon protease (S16) C-terminal proteolytic domain
I7V34_03330	COG1399	metal-binding, possibly nucleic acid-binding protein
I7V34_03335	COG0333	Belongs to the bacterial ribosomal protein bL32 family
I7V34_03340	COG1024	Enoyl-CoA hydratase
I7V34_03350	COG0454	-acetyltransferase
I7V34_03355	COG0439	Biotin carboxylase
I7V34_03360	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
I7V34_03365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I7V34_03370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
I7V34_03380	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
I7V34_03385	COG2001	Belongs to the MraZ family
I7V34_03390	COG0275	rRNA processing
I7V34_03400	COG0768	penicillin binding
I7V34_03405	COG0768	penicillin binding
I7V34_03420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I7V34_03425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
I7V34_03430	COG0772	Belongs to the SEDS family
I7V34_03435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
I7V34_03440	COG3879	Bacterial protein of unknown function (DUF881)
I7V34_03445	COG3879	Bacterial protein of unknown function (DUF881)
I7V34_03450	COG3856	small basic protein
I7V34_03455	COG0849	cell division
I7V34_03460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
I7V34_03470	COG1191	sigma factor activity
I7V34_03475	COG1191	sigma factor activity
I7V34_03480	COG1873	PFAM PRC-barrel domain
I7V34_03485	COG1496	oxidoreductase activity
I7V34_03490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
I7V34_03495	COG1799	cell septum assembly
I7V34_03500	COG0762	integral membrane protein
I7V34_03505	COG2302	S4 RNA-binding domain
I7V34_03510	COG3599	regulation of cell shape
I7V34_03520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I7V34_03525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
I7V34_03530	COG0564	pseudouridine synthase activity
I7V34_03535	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
I7V34_03550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
I7V34_03565	COG0543	2 iron, 2 sulfur cluster binding
I7V34_03570	COG0167	dihydroorotate dehydrogenase activity
I7V34_03575	COG0284	orotidine-5'-phosphate decarboxylase activity
I7V34_03580	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
I7V34_03590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
I7V34_03595	COG1561	YicC-like family, N-terminal region
I7V34_03605	COG0194	GDP metabolic process
I7V34_03615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I7V34_03620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I7V34_03625	COG0242	peptide deformylase activity
I7V34_03630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
I7V34_03635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
I7V34_03635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
I7V34_03645	COG0515	serine threonine protein kinase
I7V34_03645	COG2815	serine threonine protein kinase
I7V34_03650	COG1162	GTPase activity
I7V34_03655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I7V34_03660	COG1564	THIamine pyrophosphokinase
I7V34_03670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
I7V34_03675	COG1302	Protein conserved in bacteria
I7V34_03680	COG1461	Dihydroxyacetone kinase
I7V34_03685	COG1760	l-serine dehydratase
I7V34_03690	COG1760	l-serine dehydratase
I7V34_03695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
I7V34_03700	COG1349	DNA-binding transcription factor activity
I7V34_03705	COG0416	fatty acid biosynthetic process
I7V34_03710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I7V34_03715	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_03720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I7V34_03725	COG0571	ribonuclease III activity
I7V34_03730	COG1196	nuclear chromosome segregation
I7V34_03735	COG0552	protein localization to endoplasmic reticulum
I7V34_03740	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
I7V34_03745	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I7V34_03750	COG0228	four-way junction DNA binding
I7V34_03755	COG1837	Belongs to the UPF0109 family
I7V34_03765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
I7V34_03770	COG0336	Belongs to the RNA methyltransferase TrmD family
I7V34_03775	COG0335	large ribosomal subunit rRNA binding
I7V34_03785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I7V34_03800	COG2257	FlhB HrpN YscU SpaS Family
I7V34_03810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I7V34_03815	COG0758	DNA mediated transformation
I7V34_03820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I7V34_03825	COG4974	Belongs to the 'phage' integrase family
I7V34_03830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
I7V34_03840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
I7V34_03845	COG1815	bacterial-type flagellum-dependent cell motility
I7V34_03850	COG1558	bacterial-type flagellum-dependent cell motility
I7V34_03855	COG1677	Flagellar hook-basal body complex protein FliE
I7V34_03860	COG1766	The M ring may be actively involved in energy transduction
I7V34_03865	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I7V34_03875	COG1157	protein secretion by the type III secretion system
I7V34_03880	COG2882	bacterial-type flagellum organization
I7V34_03895	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
I7V34_03910	COG1582	Flagellar protein (FlbD)
I7V34_03915	COG1580	Controls the rotational direction of flagella during chemotaxis
I7V34_03920	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I7V34_03925	COG1776	CheC inhibitor of MCP methylation
I7V34_03925	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I7V34_03930	COG2201	protein-glutamate methylesterase activity
I7V34_03935	COG3190	flagellar
I7V34_03940	COG1338	Plays a role in the flagellum-specific transport system
I7V34_03945	COG1987	bacterial-type flagellum assembly
I7V34_03950	COG1684	flagellar biosynthetic protein fliR
I7V34_03955	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
I7V34_03960	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
I7V34_03965	COG1419	protein localization to endoplasmic reticulum
I7V34_03970	COG0455	bacterial-type flagellum organization
I7V34_03975	COG2201	protein-glutamate methylesterase activity
I7V34_03980	COG0643	Histidine kinase
I7V34_03980	COG2198	Histidine kinase
I7V34_03985	COG0835	chemotaxis
I7V34_03990	COG1776	CheC inhibitor of MCP methylation
I7V34_03995	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
I7V34_04000	COG1191	sigma factor activity
I7V34_04010	COG0052	Belongs to the universal ribosomal protein uS2 family
I7V34_04015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
I7V34_04030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
I7V34_04035	COG4589	Belongs to the CDS family
I7V34_04040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
I7V34_04045	COG0750	zinc metalloprotease
I7V34_04050	COG0442	prolyl-tRNA aminoacylation
I7V34_04055	COG2176	DNA-directed DNA polymerase activity
I7V34_04060	COG0779	Required for maturation of 30S ribosomal subunits
I7V34_04065	COG0195	Participates in both transcription termination and antitermination
I7V34_04070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
I7V34_04075	COG1358	cellular component organization or biogenesis
I7V34_04085	COG1550	Protein conserved in bacteria
I7V34_04090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
I7V34_04095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
I7V34_04100	COG0196	riboflavin kinase activity
I7V34_04110	COG1185	polyribonucleotide nucleotidyltransferase activity
I7V34_04115	COG0726	polysaccharide deacetylase
I7V34_04120	COG0612	Peptidase, M16
I7V34_04125	COG1873	PFAM PRC-barrel domain
I7V34_04130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I7V34_04135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I7V34_04140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I7V34_04145	COG0527	aspartate kinase activity
I7V34_04155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
I7V34_04160	COG0740	serine-type endopeptidase activity
I7V34_04170	COG1674	ftsk spoiiie
I7V34_04170	COG4980	gas vesicle protein
I7V34_04175	COG2188	Transcriptional regulator
I7V34_04180	COG1744	ABC transporter substrate-binding protein PnrA-like
I7V34_04185	COG3845	ABC transporter
I7V34_04190	COG4603	Belongs to the binding-protein-dependent transport system permease family
I7V34_04195	COG1079	Belongs to the binding-protein-dependent transport system permease family
I7V34_04200	COG0612	Peptidase, M16
I7V34_04205	COG0612	Peptidase, M16
I7V34_04210	COG0300	oxidoreductase activity
I7V34_04225	COG1426	Protein conserved in bacteria
I7V34_04230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I7V34_04235	COG1058	Belongs to the CinA family
I7V34_04235	COG1546	Belongs to the CinA family
I7V34_04250	COG1692	metallophosphoesterase
I7V34_04255	COG2359	stage V sporulation protein S
I7V34_04265	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
I7V34_04265	COG0674	pyruvate-flavodoxin oxidoreductase activity
I7V34_04270	COG1013	pyruvate-flavodoxin oxidoreductase activity
I7V34_04280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
I7V34_04285	COG4550	Control of competence regulator ComK, YlbF/YmcA
I7V34_04300	COG0551	DNA topoisomerase type I activity
I7V34_04300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I7V34_04310	COG1966	Carbon starvation protein
I7V34_04320	COG0493	'glutamate synthase
I7V34_04350	COG2508	Transcriptional regulator
I7V34_04355	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_04360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I7V34_04370	COG2720	vancomycin resistance protein
I7V34_04385	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
I7V34_04390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
I7V34_04395	COG0277	FAD linked oxidase domain protein
I7V34_04400	COG2271	Major facilitator Superfamily
I7V34_04410	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
I7V34_04415	COG1923	regulation of RNA biosynthetic process
I7V34_04420	COG0464	growth
I7V34_04425	COG2860	membrane
I7V34_04430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I7V34_04435	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
I7V34_04440	COG0789	Transcriptional regulator
I7V34_04445	COG0174	glutamine synthetase
I7V34_04450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
I7V34_04460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
I7V34_04465	COG4224	UPF0291 protein
I7V34_04480	COG3763	UPF0154 protein
I7V34_04490	COG1132	(ABC) transporter
I7V34_04495	COG1132	(ABC) transporter
I7V34_04505	COG0785	Cytochrome C biogenesis protein
I7V34_04510	COG2201	protein-glutamate methylesterase activity
I7V34_04515	COG4846	Membrane protein involved in cytochrome C biogenesis
I7V34_04520	COG1994	Peptidase M50
I7V34_04530	COG3852	Histidine kinase
I7V34_04555	COG0419	ATPase involved in DNA repair
I7V34_04580	COG5146	pantothenate kinase activity
I7V34_04585	COG1999	signal sequence binding
I7V34_04605	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
I7V34_04620	COG1063	alcohol dehydrogenase
I7V34_04625	COG0626	cystathionine gamma-synthase activity
I7V34_04630	COG0626	cystathionine gamma-synthase activity
I7V34_04635	COG0646	methionine synthase
I7V34_04635	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
I7V34_04640	COG1410	methionine synthase
I7V34_04640	COG0646	methionine synthase
I7V34_04650	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_04655	COG0346	lactoylglutathione lyase activity
I7V34_04660	COG0400	carboxylic ester hydrolase activity
I7V34_04670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_04690	COG2267	carboxylic ester hydrolase activity
I7V34_04700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
I7V34_04710	COG1368	sulfuric ester hydrolase activity
I7V34_04715	COG2205	protein histidine kinase activity
I7V34_04720	COG0697	spore germination
I7V34_04745	COG1183	phosphatidylcholine synthase activity
I7V34_04775	COG0659	secondary active sulfate transmembrane transporter activity
I7V34_04810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_04815	COG5566	PFAM Mor transcription activator
I7V34_04825	COG0820	rRNA (adenine-C2-)-methyltransferase activity
I7V34_04835	COG0546	phosphoglycolate phosphatase activity
I7V34_04860	COG0456	acetyltransferase
I7V34_04870	COG1595	DNA-templated transcription, initiation
I7V34_04880	COG1125	glycine betaine transport
I7V34_04880	COG0517	IMP dehydrogenase activity
I7V34_04885	COG1174	glycine betaine transport
I7V34_04900	COG1597	lipid kinase activity
I7V34_04910	COG0110	maltose O-acetyltransferase activity
I7V34_04920	COG2239	Acts as a magnesium transporter
I7V34_04930	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_04940	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
I7V34_04950	COG1834	amidinotransferase
I7V34_04955	COG1113	amino acid transport
I7V34_04960	COG2814	Major facilitator Superfamily
I7V34_04965	COG1253	flavin adenine dinucleotide binding
I7V34_04970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I7V34_04975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_04980	COG0588	phosphoglycerate mutase activity
I7V34_04990	COG1247	-acetyltransferase
I7V34_05000	COG2202	Pas domain
I7V34_05000	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_05020	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_05035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I7V34_05050	COG2124	cytochrome p450
I7V34_05060	COG1960	acyl-CoA dehydrogenase activity
I7V34_05070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I7V34_05075	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
I7V34_05080	COG1742	UPF0060 membrane protein
I7V34_05085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
I7V34_05090	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
I7V34_05095	COG1918	ferrous iron import across plasma membrane
I7V34_05095	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
I7V34_05110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_05140	COG1660	Displays ATPase and GTPase activities
I7V34_05145	COG4326	sporulation control protein
I7V34_05175	COG1309	transcriptional regulator
I7V34_05180	COG2814	Major facilitator Superfamily
I7V34_05185	COG0477	Major facilitator Superfamily
I7V34_05195	COG2226	methyltransferase
I7V34_05200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
I7V34_05205	COG4122	O-methyltransferase activity
I7V34_05210	COG0702	epimerase
I7V34_05215	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_05220	COG2340	Cysteine-rich secretory protein family
I7V34_05230	COG1011	Hydrolase
I7V34_05245	COG0500	methyltransferase
I7V34_05255	COG0768	penicillin binding
I7V34_05265	COG2217	Heavy metal translocating P-type atpase
I7V34_05290	COG1619	proteins homologs of microcin C7 resistance protein MccF
I7V34_05300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_05315	COG2309	aminopeptidase activity
I7V34_05335	COG1349	DNA-binding transcription factor activity
I7V34_05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
I7V34_05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
I7V34_05350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
I7V34_05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I7V34_05365	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_05380	COG0006	proline dipeptidase activity
I7V34_05390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I7V34_05395	COG4191	Histidine kinase
I7V34_05405	COG1380	Effector of murein hydrolase LrgA
I7V34_05410	COG1346	cytolysis
I7V34_05415	COG0024	Methionine aminopeptidase
I7V34_05425	COG1388	LysM domain
I7V34_05425	COG3584	3D domain protein
I7V34_05430	COG3584	3D domain protein
I7V34_05430	COG1388	LysM domain
I7V34_05435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I7V34_05450	COG0840	transmembrane signaling receptor activity
I7V34_05495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
I7V34_05500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_05520	COG0824	Thioesterase
I7V34_05530	COG4841	protein insertion into membrane
I7V34_05545	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
I7V34_05550	COG2233	PERMEase
I7V34_05555	COG0517	IMP dehydrogenase activity
I7V34_05555	COG1125	glycine betaine transport
I7V34_05560	COG1174	glycine betaine transport
I7V34_05565	COG1732	Glycine betaine
I7V34_05570	COG1832	CoA-binding protein
I7V34_05575	COG0187	DNA topoisomerase II activity
I7V34_05580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I7V34_05585	COG1115	amino acid carrier protein
I7V34_05660	COG4608	Belongs to the ABC transporter superfamily
I7V34_05665	COG0791	NLP P60 protein
I7V34_05670	COG4948	Mandelate Racemase Muconate Lactonizing
I7V34_05675	COG1619	proteins homologs of microcin C7 resistance protein MccF
I7V34_05680	COG4166	transmembrane transport
I7V34_05685	COG0444	Belongs to the ABC transporter superfamily
I7V34_05690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I7V34_05695	COG0601	transmembrane transport
I7V34_05700	COG2362	D-Aminopeptidase
I7V34_05705	COG2233	PERMEase
I7V34_05710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I7V34_05715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_05715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_05725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I7V34_05730	COG2022	thiamine diphosphate biosynthetic process
I7V34_05740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I7V34_05745	COG0352	thiamine-phosphate diphosphorylase activity
I7V34_05755	COG4172	Belongs to the ABC transporter superfamily
I7V34_05765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
I7V34_05770	COG2197	response regulator
I7V34_05775	COG4585	Histidine kinase
I7V34_05800	COG0708	Exodeoxyribonuclease III
I7V34_05825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_05840	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
I7V34_05860	COG1011	Hydrolase
I7V34_05875	COG3493	citrate carrier protein
I7V34_05880	COG4565	transcriptional regulatory protein
I7V34_05885	COG3290	protein histidine kinase activity
I7V34_05900	COG0745	RESPONSE REGULATOR receiver
I7V34_05905	COG5002	protein histidine kinase activity
I7V34_05910	COG1999	signal sequence binding
I7V34_05915	COG0450	alkyl hydroperoxide reductase
I7V34_05940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
I7V34_05950	COG0352	thiamine-phosphate diphosphorylase activity
I7V34_05955	COG0351	phosphomethylpyrimidine kinase
I7V34_05960	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
I7V34_05970	COG1620	l-lactate permease
I7V34_05975	COG1414	Transcriptional regulator
I7V34_05985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
I7V34_05990	COG0277	FAD linked oxidase domain protein
I7V34_05995	COG0247	lactate metabolic process
I7V34_06000	COG0277	FAD linked oxidase domain protein
I7V34_06005	COG2186	Transcriptional regulator
I7V34_06015	COG5632	N-Acetylmuramoyl-L-alanine amidase
I7V34_06065	COG0456	acetyltransferase
I7V34_06095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I7V34_06115	COG0300	oxidoreductase activity
I7V34_06150	COG2814	Major facilitator Superfamily
I7V34_06170	COG1131	(ABC) transporter
I7V34_06175	COG1309	transcriptional regulator
I7V34_06185	COG1162	GTPase activity
I7V34_06200	COG3620	sequence-specific DNA binding
I7V34_06220	COG0842	Transport permease protein
I7V34_06220	COG1511	domain protein
I7V34_06225	COG1131	(ABC) transporter
I7V34_06240	COG0488	(ABC) transporter
I7V34_06245	COG0662	Cupin 2, conserved barrel domain protein
I7V34_06250	COG2205	protein histidine kinase activity
I7V34_06280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I7V34_06290	COG0693	protein deglycase activity
I7V34_06330	COG1879	ABC-type sugar transport system periplasmic component
I7V34_06335	COG1172	Belongs to the binding-protein-dependent transport system permease family
I7V34_06340	COG1129	ABC transporter
I7V34_06345	COG1869	D-ribose catabolic process
I7V34_06350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I7V34_06355	COG1609	Transcriptional regulator
I7V34_06360	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_06365	COG1595	DNA-templated transcription, initiation
I7V34_06390	COG2205	protein histidine kinase activity
I7V34_06395	COG0745	RESPONSE REGULATOR receiver
I7V34_06420	COG2153	protein acetylation
I7V34_06430	COG1959	2 iron, 2 sulfur cluster binding
I7V34_06435	COG1393	Belongs to the ArsC family
I7V34_06440	COG0456	acetyltransferase
I7V34_06480	COG2211	Major facilitator Superfamily
I7V34_06490	COG5002	protein histidine kinase activity
I7V34_06490	COG3850	Histidine kinase
I7V34_06495	COG0745	RESPONSE REGULATOR receiver
I7V34_06505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I7V34_06510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I7V34_06565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
I7V34_06570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
I7V34_06580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I7V34_06590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I7V34_06595	COG2304	oxidoreductase activity
I7V34_06620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_06630	COG1335	isochorismatase
I7V34_06705	COG3340	Belongs to the peptidase S51 family
I7V34_06725	COG3852	Histidine kinase
I7V34_06770	COG1051	belongs to the nudix hydrolase family
I7V34_06780	COG0124	histidyl-tRNA synthetase
I7V34_06790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
I7V34_06795	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
I7V34_06800	COG2323	membrane
I7V34_06810	COG0028	Belongs to the TPP enzyme family
I7V34_06815	COG2070	2-Nitropropane dioxygenase
I7V34_06895	COG0778	Nitroreductase
I7V34_06905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
I7V34_06910	COG0561	phosphatase activity
I7V34_06945	COG0592	DNA-directed DNA polymerase activity
I7V34_06990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_06990	COG3711	transcriptional antiterminator
I7V34_07010	COG0456	acetyltransferase
I7V34_07020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_07105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
I7V34_07110	COG1349	DNA-binding transcription factor activity
I7V34_07115	COG3842	ATPase activity
I7V34_07125	COG0395	ABC-type sugar transport system, permease component
I7V34_07195	COG2323	membrane
I7V34_07220	COG0590	tRNA wobble adenosine to inosine editing
I7V34_07225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I7V34_07245	COG1522	sequence-specific DNA binding
I7V34_07250	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I7V34_07265	COG0640	Transcriptional regulator
I7V34_07275	COG2226	methyltransferase
I7V34_07325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
I7V34_07350	COG1051	belongs to the nudix hydrolase family
I7V34_07360	COG2226	methyltransferase
I7V34_07365	COG3227	Zinc metalloprotease (Elastase)
I7V34_07390	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_07400	COG5002	protein histidine kinase activity
I7V34_07400	COG3850	Histidine kinase
I7V34_07405	COG0745	RESPONSE REGULATOR receiver
I7V34_07415	COG4086	secreted protein
I7V34_07420	COG4191	Histidine kinase
I7V34_07425	COG0730	response to heat
I7V34_07430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_07430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_07435	COG0425	Belongs to the sulfur carrier protein TusA family
I7V34_07435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_07440	COG2210	Belongs to the sulfur carrier protein TusA family
I7V34_07445	COG0425	Belongs to the sulfur carrier protein TusA family
I7V34_07450	COG1937	Protein conserved in bacteria
I7V34_07455	COG0003	Pfam Anion-transporting ATPase
I7V34_07465	COG1966	Carbon starvation protein
I7V34_07480	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
I7V34_07490	COG2323	membrane
I7V34_07495	COG2309	aminopeptidase activity
I7V34_07505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
I7V34_07515	COG0517	IMP dehydrogenase activity
I7V34_07515	COG0516	GMP reductase activity
I7V34_07520	COG2176	DNA-directed DNA polymerase activity
I7V34_07525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
I7V34_07530	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
I7V34_07535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I7V34_07560	COG1120	ATPase activity
I7V34_07565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I7V34_07570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I7V34_07575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I7V34_07590	COG2996	Protein conserved in bacteria
I7V34_07595	COG2223	nitrite transmembrane transporter activity
I7V34_07615	COG0488	(ABC) transporter
I7V34_07620	COG0514	ATP-dependent DNA helicase (RecQ)
I7V34_07655	COG1686	Belongs to the peptidase S11 family
I7V34_07665	COG3853	Toxic anion resistance protein (TelA)
I7V34_07675	COG4548	von Willebrand factor, type A
I7V34_07680	COG0714	Associated with various cellular activities
I7V34_07700	COG0586	Pfam SNARE associated Golgi protein
I7V34_07705	COG2105	PFAM AIG2 family protein
I7V34_07710	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_07720	COG0508	dehydrogenase complex catalyzes the overall conversion of
I7V34_07725	COG0567	Dehydrogenase, E1 component
I7V34_07735	COG5002	protein histidine kinase activity
I7V34_07745	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
I7V34_07750	COG0432	Pfam Uncharacterised protein family UPF0047
I7V34_07755	COG3011	Protein conserved in bacteria
I7V34_07760	COG0406	alpha-ribazole phosphatase activity
I7V34_07805	COG2076	Multidrug Resistance protein
I7V34_07825	COG0697	spore germination
I7V34_07830	COG3541	Predicted nucleotidyltransferase
I7V34_07835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I7V34_07850	COG1278	Cold shock
I7V34_07865	COG0494	nUDIX hydrolase
I7V34_07890	COG2226	methyltransferase
I7V34_07895	COG0446	pyridine nucleotide-disulphide oxidoreductase
I7V34_07915	COG0134	indole-3-glycerol-phosphate synthase activity
I7V34_07920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
I7V34_07925	COG0512	Glutamine amidotransferase of anthranilate synthase
I7V34_07940	COG4145	pantothenate transmembrane transporter activity
I7V34_07950	COG5522	Integral membrane protein (intg_mem_TP0381)
I7V34_07960	COG0671	phosphoesterase, PA-phosphatase related
I7V34_07965	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
I7V34_07970	COG3285	dna ligase
I7V34_07970	COG1793	dna ligase
I7V34_07985	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
I7V34_07995	COG1942	4-Oxalocrotonate Tautomerase
I7V34_08000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
I7V34_08010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I7V34_08035	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_08040	COG0251	oxidation-reduction process
I7V34_08055	COG0431	NADPH-dependent FMN reductase
I7V34_08060	COG0196	riboflavin kinase activity
I7V34_08065	COG2368	4-hydroxyphenylacetate
I7V34_08075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I7V34_08085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
I7V34_08085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
I7V34_08090	COG0307	riboflavin synthase, alpha
I7V34_08095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I7V34_08095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I7V34_08110	COG4667	esterase of the alpha-beta hydrolase superfamily
I7V34_08115	COG0494	nUDIX hydrolase
I7V34_08120	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
I7V34_08125	COG1131	(ABC) transporter
I7V34_08150	COG0586	Pfam SNARE associated Golgi protein
I7V34_08155	COG1228	amidohydrolase
I7V34_08175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I7V34_08180	COG0534	Mate efflux family protein
I7V34_08185	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_08190	COG2340	Cysteine-rich secretory protein family
I7V34_08210	COG0523	cobalamin synthesis protein
I7V34_08225	COG0793	Belongs to the peptidase S41A family
I7V34_08225	COG3409	Peptidoglycan-binding domain 1 protein
I7V34_08235	COG1876	peptidase activity
I7V34_08255	COG4326	sporulation control protein
I7V34_08275	COG4479	Belongs to the UPF0346 family
I7V34_08285	COG1509	lysine 2,3-aminomutase activity
I7V34_08290	COG0456	acetyltransferase
I7V34_08295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I7V34_08300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I7V34_08305	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I7V34_08310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I7V34_08315	COG0840	transmembrane signaling receptor activity
I7V34_08315	COG5278	phosphoserine phosphatase activity
I7V34_08330	COG2190	(PTS) system
I7V34_08335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I7V34_08340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I7V34_08360	COG2755	lipolytic protein G-D-S-L family
I7V34_08365	COG1307	EDD domain protein, DegV family
I7V34_08375	COG2135	peptidase activity
I7V34_08380	COG1272	protein, Hemolysin III
I7V34_08385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
I7V34_08405	COG2136	Putative SAM-dependent methyltransferase
I7V34_08405	COG2521	methyltransferase
I7V34_08415	COG1413	lyase activity
I7V34_08420	COG0488	(ABC) transporter
I7V34_08425	COG1418	mRNA catabolic process
I7V34_08430	COG1307	EDD domain protein, DegV family
I7V34_08455	COG1321	iron dependent repressor
I7V34_08460	COG1278	Cold shock
I7V34_08470	COG0328	RNA-DNA hybrid ribonuclease activity
I7V34_08475	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
I7V34_08480	COG0328	RNA-DNA hybrid ribonuclease activity
I7V34_08500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I7V34_08505	COG2897	thiosulfate sulfurtransferase activity
I7V34_08515	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
I7V34_08525	COG3424	synthase
I7V34_08530	COG1406	Chemotaxis phosphatase CheX
I7V34_08535	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_08545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I7V34_08550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I7V34_08555	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
I7V34_08575	COG1199	ATP-dependent helicase activity
I7V34_08585	COG0116	Belongs to the methyltransferase superfamily
I7V34_08595	COG3599	regulation of cell shape
I7V34_08600	COG4474	Belongs to the UPF0398 family
I7V34_08610	COG3359	exonuclease
I7V34_08615	COG1205	dead DEAH box helicase
I7V34_08615	COG1111	helicase
I7V34_08625	COG0071	Belongs to the small heat shock protein (HSP20) family
I7V34_08660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I7V34_08660	COG4499	WXG100 protein secretion system (Wss), protein YukC
I7V34_08670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I7V34_08675	COG3935	DnaD domain protein
I7V34_08680	COG0017	Asparaginyl-tRNA synthetase
I7V34_08685	COG0436	Aminotransferase
I7V34_08705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I7V34_08705	COG1199	ATP-dependent helicase activity
I7V34_08710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
I7V34_08715	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
I7V34_08720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
I7V34_08735	COG0438	transferase activity, transferring glycosyl groups
I7V34_08740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I7V34_08745	COG1803	Methylglyoxal synthase
I7V34_08755	COG1694	Mazg nucleotide pyrophosphohydrolase
I7V34_08760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_08765	COG2738	Putative neutral zinc metallopeptidase
I7V34_08775	COG4347	Protein of unknown function (DUF1405)
I7V34_08785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
I7V34_08805	COG0457	Tetratricopeptide repeat
I7V34_08815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
I7V34_08820	COG0287	Prephenate dehydrogenase
I7V34_08825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
I7V34_08830	COG4401	Chorismate mutase type I
I7V34_08835	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
I7V34_08840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
I7V34_08845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
I7V34_08850	COG0105	UTP biosynthetic process
I7V34_08855	COG0142	geranyltranstransferase activity
I7V34_08860	COG2226	methyltransferase
I7V34_08865	COG0142	geranyltranstransferase activity
I7V34_08875	COG0302	gtp cyclohydrolase
I7V34_08880	COG0776	regulation of translation
I7V34_08885	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
I7V34_08900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
I7V34_08905	COG1160	GTP binding
I7V34_08935	COG0539	negative regulation of cytoplasmic translation
I7V34_08940	COG0204	Acyl-transferase
I7V34_08945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
I7V34_08960	COG2959	enzyme of heme biosynthesis
I7V34_08965	COG3409	Peptidoglycan-binding domain 1 protein
I7V34_08965	COG3773	Cell wall hydrolase
I7V34_08975	COG2339	peptidase activity
I7V34_08985	COG0492	ferredoxin-NADP+ reductase activity
I7V34_08990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I7V34_08995	COG4862	establishment of competence for transformation
I7V34_09000	COG0789	Transcriptional regulator
I7V34_09005	COG1408	metallophosphoesterase
I7V34_09030	COG3546	catalase activity
I7V34_09040	COG1388	LysM domain
I7V34_09045	COG1266	CAAX protease self-immunity
I7V34_09050	COG0514	ATP-dependent DNA helicase (RecQ)
I7V34_09055	COG4955	Helix-turn-helix domain
I7V34_09060	COG1141	Ferredoxin
I7V34_09065	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
I7V34_09070	COG0739	heme binding
I7V34_09080	COG1595	DNA-templated transcription, initiation
I7V34_09085	COG5002	protein histidine kinase activity
I7V34_09090	COG0745	RESPONSE REGULATOR receiver
I7V34_09095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I7V34_09100	COG1333	cytochrome c biogenesis protein
I7V34_09105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_09110	COG1187	pseudouridine synthase activity
I7V34_09120	COG0700	Nucleoside recognition
I7V34_09125	COG2715	membrane protein required for spore maturation
I7V34_09130	COG1686	Belongs to the peptidase S11 family
I7V34_09135	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
I7V34_09140	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
I7V34_09145	COG1547	Domain of unknown function (DUF309)
I7V34_09160	COG0697	spore germination
I7V34_09195	COG1686	Belongs to the peptidase S11 family
I7V34_09210	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
I7V34_09215	COG4974	Belongs to the 'phage' integrase family
I7V34_09225	COG0735	belongs to the Fur family
I7V34_09230	COG1300	Membrane
I7V34_09245	COG0667	Aldo Keto reductase
I7V34_09255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I7V34_09260	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I7V34_09265	COG0183	Belongs to the thiolase family
I7V34_09270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I7V34_09275	COG1073	alpha beta
I7V34_09285	COG4918	Iron-sulphur cluster biosynthesis
I7V34_09300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
I7V34_09310	COG4975	Glucose uptake
I7V34_09320	COG0300	oxidoreductase activity
I7V34_09325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_09330	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I7V34_09335	COG1902	pentaerythritol trinitrate reductase activity
I7V34_09345	COG1234	tRNA 3'-trailer cleavage
I7V34_09350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
I7V34_09355	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
I7V34_09370	COG2195	Cleaves the N-terminal amino acid of tripeptides
I7V34_09375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I7V34_09380	COG0346	lactoylglutathione lyase activity
I7V34_09390	COG1376	ErfK ybiS ycfS ynhG family protein
I7V34_09395	COG4129	membrane
I7V34_09400	COG1126	abc transporter atp-binding protein
I7V34_09405	COG0765	amino acid transport
I7V34_09410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I7V34_09425	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I7V34_09425	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I7V34_09430	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I7V34_09435	COG1404	Belongs to the peptidase S8 family
I7V34_09435	COG4412	M6 family metalloprotease domain protein
I7V34_09440	COG0508	dehydrogenase complex catalyzes the overall conversion of
I7V34_09445	COG0022	dehydrogenase e1 component
I7V34_09450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I7V34_09455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I7V34_09465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I7V34_09470	COG0280	phosphate acetyltransferase
I7V34_09475	COG3290	protein histidine kinase activity
I7V34_09475	COG3829	transcription factor binding
I7V34_09485	COG0584	glycerophosphoryl diester phosphodiesterase
I7V34_09495	COG0750	zinc metalloprotease
I7V34_09500	COG0497	DNA recombination
I7V34_09510	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
I7V34_09515	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
I7V34_09535	COG1570	exodeoxyribonuclease VII activity
I7V34_09540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
I7V34_09545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
I7V34_09550	COG1302	Protein conserved in bacteria
I7V34_09555	COG0439	Biotin carboxylase
I7V34_09560	COG0511	ligase activity, forming carbon-carbon bonds
I7V34_09600	COG3854	ATPases associated with a variety of cellular activities
I7V34_09605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
I7V34_09610	COG0006	proline dipeptidase activity
I7V34_09630	COG1752	Esterase of the alpha-beta hydrolase superfamily
I7V34_09635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I7V34_09645	COG0095	Lipoate-protein ligase
I7V34_09650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_09655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I7V34_09660	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I7V34_09665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
I7V34_09670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I7V34_09710	COG4537	Required for transformation and DNA binding
I7V34_09720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I7V34_09730	COG1393	Belongs to the ArsC family
I7V34_09740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_09750	COG0011	TIGRFAM Protein of
I7V34_09765	COG1368	sulfuric ester hydrolase activity
I7V34_09770	COG1940	carbohydrate kinase activity
I7V34_09780	COG0697	spore germination
I7V34_09790	COG0457	Tetratricopeptide repeat
I7V34_09790	COG0705	Rhomboid family
I7V34_09805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
I7V34_09810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
I7V34_09820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
I7V34_09845	COG0840	transmembrane signaling receptor activity
I7V34_09850	COG0704	Plays a role in the regulation of phosphate uptake
I7V34_09855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I7V34_09860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I7V34_09865	COG0581	inorganic phosphate transmembrane transporter activity
I7V34_09870	COG0573	inorganic phosphate transmembrane transporter activity
I7V34_09875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
I7V34_09880	COG0768	penicillin binding
I7V34_09885	COG0477	Major facilitator Superfamily
I7V34_09895	COG2839	Protein conserved in bacteria
I7V34_09900	COG1283	sodium-dependent phosphate transmembrane transporter activity
I7V34_09905	COG2814	Major facilitator Superfamily
I7V34_09915	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
I7V34_09920	COG4709	membrane
I7V34_09925	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
I7V34_09930	COG0735	belongs to the Fur family
I7V34_09935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I7V34_09940	COG1121	(ABC) transporter
I7V34_09950	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
I7V34_09955	COG0513	Belongs to the DEAD box helicase family
I7V34_09965	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
I7V34_09970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
I7V34_09975	COG2384	SAM-dependent methyltransferase
I7V34_09980	COG2010	Cytochrome c
I7V34_09985	COG1960	acyl-CoA dehydrogenase activity
I7V34_09995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
I7V34_10000	COG0358	DNA primase activity
I7V34_10005	COG1671	Belongs to the UPF0178 family
I7V34_10015	COG0517	IMP dehydrogenase activity
I7V34_10025	COG1381	Involved in DNA repair and RecF pathway recombination
I7V34_10040	COG0295	cytidine deaminase activity
I7V34_10050	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
I7V34_10055	COG1480	7TM receptor with intracellular HD hydrolase
I7V34_10060	COG1702	phosphate starvation-inducible protein PhoH
I7V34_10080	COG4864	UPF0365 protein
I7V34_10085	COG1030	water channel activity
I7V34_10090	COG1610	YqeY-like protein
I7V34_10100	COG1283	sodium-dependent phosphate transmembrane transporter activity
I7V34_10110	COG0366	Alpha amylase catalytic
I7V34_10115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
I7V34_10120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I7V34_10130	COG0484	heat shock protein binding
I7V34_10135	COG0443	Heat shock 70 kDa protein
I7V34_10140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
I7V34_10145	COG1420	regulation of RNA biosynthetic process
I7V34_10150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I7V34_10155	COG0481	GTPase activity
I7V34_10165	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_10175	COG0268	Binds directly to 16S ribosomal RNA
I7V34_10180	COG1466	dna polymerase III delta subunit
I7V34_10190	COG0658	competence protein
I7V34_10190	COG2333	competence protein COMEC
I7V34_10195	COG2131	deaminase
I7V34_10200	COG1555	photosystem II stabilization
I7V34_10200	COG1596	polysaccharide export
I7V34_10205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I7V34_10210	COG2226	methyltransferase
I7V34_10215	COG0799	negative regulation of ribosome biogenesis
I7V34_10220	COG1713	HD superfamily hydrolase involved in NAD metabolism
I7V34_10225	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
I7V34_10230	COG1534	Rna-binding protein
I7V34_10240	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I7V34_10245	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
I7V34_10260	COG1183	phosphatidylcholine synthase activity
I7V34_10275	COG0640	Transcriptional regulator
I7V34_10285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I7V34_10290	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I7V34_10295	COG0640	Transcriptional regulator
I7V34_10320	COG0626	cystathionine gamma-synthase activity
I7V34_10325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I7V34_10330	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I7V34_10335	COG2226	methyltransferase
I7V34_10350	COG0768	penicillin binding
I7V34_10355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
I7V34_10360	COG0572	uridine kinase
I7V34_10365	COG0826	peptidase U32
I7V34_10370	COG0826	peptidase U32
I7V34_10375	COG4122	O-methyltransferase activity
I7V34_10380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I7V34_10385	COG3906	Belongs to the UPF0473 family
I7V34_10390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
I7V34_10395	COG4472	Bacterial protein of unknown function (DUF965)
I7V34_10405	COG0628	permease
I7V34_10420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
I7V34_10425	COG1268	BioY protein
I7V34_10430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I7V34_10440	COG0482	sulfurtransferase activity
I7V34_10445	COG1104	cysteine desulfurase activity
I7V34_10450	COG1959	2 iron, 2 sulfur cluster binding
I7V34_10455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I7V34_10465	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
I7V34_10470	COG1131	(ABC) transporter
I7V34_10475	COG1131	(ABC) transporter
I7V34_10480	COG1725	Transcriptional regulator
I7V34_10495	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
I7V34_10505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
I7V34_10510	COG0124	histidyl-tRNA synthetase
I7V34_10520	COG3103	Sh3 type 3 domain protein
I7V34_10520	COG4991	sh3 domain protein
I7V34_10520	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_10525	COG1490	D-aminoacyl-tRNA deacylase activity
I7V34_10530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I7V34_10535	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I7V34_10540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
I7V34_10540	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
I7V34_10545	COG5416	Lipopolysaccharide assembly protein A domain
I7V34_10550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I7V34_10555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I7V34_10555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I7V34_10565	COG2244	polysaccharide biosynthetic process
I7V34_10570	COG2323	membrane
I7V34_10575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I7V34_10585	COG1862	Preprotein translocase
I7V34_10595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
I7V34_10630	COG1388	LysM domain
I7V34_10635	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
I7V34_10640	COG0157	Belongs to the NadC ModD family
I7V34_10645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
I7V34_10650	COG1104	cysteine desulfurase activity
I7V34_10655	COG1827	regulation of RNA biosynthetic process
I7V34_10660	COG0077	Prephenate dehydratase
I7V34_10665	COG4492	Belongs to the UPF0735 family
I7V34_10670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
I7V34_10675	COG3290	protein histidine kinase activity
I7V34_10680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
I7V34_10685	COG2868	ribosomal protein
I7V34_10690	COG0261	This protein binds to 23S rRNA in the presence of protein L20
I7V34_10695	COG1530	ribonuclease E activity
I7V34_10700	COG1994	Peptidase M50
I7V34_10705	COG0739	heme binding
I7V34_10710	COG2894	cell division
I7V34_10715	COG0850	regulation of cytokinetic process
I7V34_10720	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
I7V34_10725	COG1792	Involved in formation and maintenance of cell shape
I7V34_10730	COG1077	Cell shape determining protein MreB Mrl
I7V34_10735	COG2003	Belongs to the UPF0758 family
I7V34_10765	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
I7V34_10770	COG2165	general secretion pathway protein
I7V34_10775	COG1459	type II secretion system
I7V34_10785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I7V34_10800	COG3706	GGDEF domain
I7V34_10805	COG0285	dihydrofolate synthase activity
I7V34_10810	COG0525	valine-tRNA ligase activity
I7V34_10820	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I7V34_10825	COG1388	LysM domain
I7V34_10825	COG1388	LysM domain
I7V34_10830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
I7V34_10835	COG0113	porphobilinogen synthase activity
I7V34_10850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I7V34_10865	COG5553	Cysteine dioxygenase type I
I7V34_10870	COG0697	spore germination
I7V34_10875	COG1126	abc transporter atp-binding protein
I7V34_10880	COG0765	amino acid transport
I7V34_10885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I7V34_10890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
I7V34_10895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I7V34_10900	COG0470	DNA polymerase III
I7V34_10900	COG1067	ATP-dependent peptidase activity
I7V34_10905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
I7V34_10910	COG0544	peptidyl-prolyl cis-trans isomerase activity
I7V34_10915	COG0457	Tetratricopeptide repeat
I7V34_10915	COG1477	protein flavinylation
I7V34_10925	COG0622	Phosphoesterase
I7V34_10940	COG5401	PFAM Sporulation and spore germination
I7V34_10955	COG1846	Transcriptional regulator
I7V34_10960	COG2197	response regulator
I7V34_10965	COG0824	Thioesterase
I7V34_10970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I7V34_10975	COG1053	succinate dehydrogenase
I7V34_10980	COG2009	succinate dehydrogenase
I7V34_10985	COG1719	4-vinyl reductase, 4VR
I7V34_10995	COG0322	excinuclease ABC activity
I7V34_11000	COG3118	belongs to the thioredoxin family
I7V34_11005	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
I7V34_11010	COG2086	electron transfer activity
I7V34_11015	COG1024	Enoyl-CoA hydratase
I7V34_11020	COG1309	transcriptional regulator
I7V34_11025	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_11030	COG3459	Glycosyltransferase 36 associated
I7V34_11035	COG3766	membrane
I7V34_11040	COG1193	negative regulation of DNA recombination
I7V34_11045	COG1796	DNA polymerase
I7V34_11045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
I7V34_11050	COG1286	toxin biosynthetic process
I7V34_11055	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
I7V34_11065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I7V34_11065	COG0072	phenylalanine-tRNA ligase activity
I7V34_11070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
I7V34_11080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I7V34_11090	COG1335	isochorismatase
I7V34_11095	COG1363	Peptidase, m42
I7V34_11120	COG1181	Belongs to the D-alanine--D-alanine ligase family
I7V34_11125	COG0189	ligase activity
I7V34_11130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I7V34_11145	COG0398	Pfam SNARE associated Golgi protein
I7V34_11155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
I7V34_11165	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
I7V34_11170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
I7V34_11180	COG1484	DNA-dependent DNA replication
I7V34_11185	COG3611	Membrane attachment protein
I7V34_11190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
I7V34_11200	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
I7V34_11205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I7V34_11215	COG1971	Probably functions as a manganese efflux pump
I7V34_11220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
I7V34_11225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I7V34_11225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I7V34_11230	COG0330	HflC and HflK could
I7V34_11235	COG0330	HflC and HflK could
I7V34_11240	COG5002	protein histidine kinase activity
I7V34_11245	COG0745	RESPONSE REGULATOR receiver
I7V34_11255	COG0039	L-malate dehydrogenase activity
I7V34_11260	COG0538	isocitrate dehydrogenase activity
I7V34_11265	COG0372	Belongs to the citrate synthase family
I7V34_11270	COG0628	permease
I7V34_11275	COG3030	protein affecting phage T7 exclusion by the F plasmid
I7V34_11285	COG0205	6-phosphofructokinase activity
I7V34_11290	COG0825	malonyl-CoA metabolic process
I7V34_11295	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
I7V34_11300	COG1725	Transcriptional regulator
I7V34_11305	COG0281	malic enzyme
I7V34_11310	COG0587	DNA-directed DNA polymerase activity
I7V34_11325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
I7V34_11335	COG4109	DRTGG domain
I7V34_11365	COG0589	response to stress
I7V34_11370	COG0165	Argininosuccinate lyase
I7V34_11375	COG0137	argininosuccinate synthase activity
I7V34_11385	COG2217	Heavy metal translocating P-type atpase
I7V34_11390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
I7V34_11395	COG0827	DNA restriction-modification system
I7V34_11400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
I7V34_11405	COG3874	Sporulation protein YtfJ
I7V34_11415	COG1714	RDD family
I7V34_11420	COG0616	signal peptide processing
I7V34_11425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
I7V34_11430	COG2962	Rard protein
I7V34_11435	COG1574	metal-dependent hydrolase with the TIM-barrel fold
I7V34_11440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I7V34_11450	COG0301	tRNA thio-modification
I7V34_11455	COG1104	cysteine desulfurase activity
I7V34_11460	COG1114	Component of the transport system for branched-chain amino acids
I7V34_11465	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
I7V34_11470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
I7V34_11475	COG1309	transcriptional regulator
I7V34_11480	COG1956	GAF domain-containing protein
I7V34_11490	COG2199	diguanylate cyclase activity
I7V34_11490	COG2203	Gaf domain
I7V34_11495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
I7V34_11500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
I7V34_11505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I7V34_11510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I7V34_11515	COG0454	-acetyltransferase
I7V34_11520	COG0517	IMP dehydrogenase activity
I7V34_11525	COG0123	including yeast histone deacetylase and acetoin utilization protein
I7V34_11545	COG1605	Chorismate mutase
I7V34_11545	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
I7V34_11550	COG0849	cell division
I7V34_11565	COG4980	gas vesicle protein
I7V34_11580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
I7V34_11590	COG1674	ftsk spoiiie
I7V34_11595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I7V34_11600	COG4848	Belongs to the UPF0354 family
I7V34_11605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_11625	COG3104	oligopeptide transport
I7V34_11635	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
I7V34_11640	COG1363	Peptidase, m42
I7V34_11650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_11655	COG0220	tRNA (guanine-N7-)-methyltransferase activity
I7V34_11665	COG0510	thiamine kinase activity
I7V34_11670	COG1523	belongs to the glycosyl hydrolase 13 family
I7V34_11675	COG1597	lipid kinase activity
I7V34_11690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I7V34_11705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I7V34_11710	COG1349	DNA-binding transcription factor activity
I7V34_11715	COG1187	pseudouridine synthase activity
I7V34_11725	COG2244	polysaccharide biosynthetic process
I7V34_11730	COG2081	HI0933 family
I7V34_11740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_11745	COG0495	leucyl-tRNA aminoacylation
I7V34_11750	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_11755	COG2610	gluconate transmembrane transporter activity
I7V34_11760	COG3290	protein histidine kinase activity
I7V34_11760	COG3829	transcription factor binding
I7V34_11765	COG4297	protein containing double-stranded beta helix domain
I7V34_11770	COG3547	Transposase (IS116 IS110 IS902 family)
I7V34_11775	COG2814	Major facilitator Superfamily
I7V34_11790	COG1242	4 iron, 4 sulfur cluster binding
I7V34_11795	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
I7V34_11800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I7V34_11815	COG2267	carboxylic ester hydrolase activity
I7V34_11820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I7V34_11825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
I7V34_11830	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
I7V34_11845	COG1268	BioY protein
I7V34_11860	COG1506	peptidase
I7V34_11865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I7V34_11870	COG1116	anion transmembrane transporter activity
I7V34_11875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I7V34_11910	COG1854	S-ribosylhomocysteine lyase activity
I7V34_11915	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
I7V34_11925	COG1271	oxidase subunit
I7V34_11930	COG1294	oxidase, subunit
I7V34_11935	COG4948	Mandelate Racemase Muconate Lactonizing
I7V34_11940	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_11945	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
I7V34_11950	COG0596	Alpha beta hydrolase
I7V34_11955	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
I7V34_11960	COG1169	isochorismate synthase
I7V34_11965	COG1575	Belongs to the MenA family. Type 1 subfamily
I7V34_11970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I7V34_11975	COG0058	SHG alpha-glucan phosphorylase activity
I7V34_11980	COG0297	glycogen (starch) synthase activity
I7V34_11985	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
I7V34_11990	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
I7V34_12000	COG0246	Mannitol dehydrogenase
I7V34_12005	COG3711	transcriptional antiterminator
I7V34_12010	COG2213	PTS system mannitol-specific
I7V34_12010	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_12150	COG1285	pathogenesis
I7V34_12155	COG1285	pathogenesis
I7V34_12160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I7V34_12160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I7V34_12160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_12165	COG1105	Belongs to the carbohydrate kinase PfkB family
I7V34_12170	COG1349	DNA-binding transcription factor activity
I7V34_12175	COG1368	sulfuric ester hydrolase activity
I7V34_12180	COG0561	phosphatase activity
I7V34_12185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I7V34_12200	COG1607	acyl-coa hydrolase
I7V34_12205	COG0583	DNA-binding transcription factor activity
I7V34_12220	COG3876	Protein conserved in bacteria
I7V34_12225	COG1472	Belongs to the glycosyl hydrolase 3 family
I7V34_12230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I7V34_12235	COG0415	Belongs to the DNA photolyase family
I7V34_12250	COG1595	DNA-templated transcription, initiation
I7V34_12265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_12270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I7V34_12285	COG1979	alcohol dehydrogenase
I7V34_12290	COG2155	Conserved Protein
I7V34_12295	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_12300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I7V34_12305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I7V34_12310	COG3829	transcription factor binding
I7V34_12315	COG0753	catalase activity
I7V34_12325	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_12335	COG1098	S1 RNA binding domain
I7V34_12345	COG1595	DNA-templated transcription, initiation
I7V34_12355	COG0733	neurotransmitter:sodium symporter activity
I7V34_12365	COG0436	Aminotransferase
I7V34_12370	COG1522	sequence-specific DNA binding
I7V34_12375	COG2267	carboxylic ester hydrolase activity
I7V34_12380	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
I7V34_12385	COG2032	superoxide dismutase activity
I7V34_12395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I7V34_12405	COG5018	Exonuclease
I7V34_12410	COG2814	Major facilitator Superfamily
I7V34_12415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I7V34_12435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I7V34_12435	COG2111	Na H antiporter
I7V34_12440	COG2111	Na H antiporter
I7V34_12445	COG1006	Multisubunit Na H antiporter MnhC subunit
I7V34_12450	COG0651	ATP synthesis coupled electron transport
I7V34_12455	COG1863	multisubunit Na H antiporter MnhE subunit
I7V34_12460	COG2212	antiporter activity
I7V34_12465	COG1320	monovalent cation:proton antiporter activity
I7V34_12470	COG4876	unkown
I7V34_12475	COG2050	protein possibly involved in aromatic compounds catabolism
I7V34_12500	COG2056	Na+-H+ antiporter family
I7V34_12505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
I7V34_12510	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
I7V34_12515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I7V34_12520	COG3584	3D domain protein
I7V34_12545	COG1252	NADH dehydrogenase
I7V34_12560	COG0316	Belongs to the HesB IscA family
I7V34_12575	COG4844	belongs to the
I7V34_12580	COG1252	NADH dehydrogenase
I7V34_12585	COG4837	Protein of unknown function (DUF1462)
I7V34_12590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
I7V34_12600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I7V34_12605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I7V34_12610	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I7V34_12630	COG0647	UMP catabolic process
I7V34_12635	COG2445	Protein of unknown function DUF86
I7V34_12650	COG4470	Protein conserved in bacteria
I7V34_12660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
I7V34_12665	COG0739	heme binding
I7V34_12675	COG0733	neurotransmitter:sodium symporter activity
I7V34_12680	COG1231	oxidoreductase activity
I7V34_12685	COG1757	Na H antiporter
I7V34_12700	COG3377	Domain of unknown function (DUF1805)
I7V34_12705	COG0737	Belongs to the 5'-nucleotidase family
I7V34_12710	COG0730	response to heat
I7V34_12715	COG1801	Protein of unknown function DUF72
I7V34_12720	COG0719	Fe-S assembly protein
I7V34_12725	COG0822	iron-sulfur transferase activity
I7V34_12730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I7V34_12735	COG0719	Fe-S assembly protein
I7V34_12740	COG0396	ATPase activity
I7V34_12750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I7V34_12755	COG1464	Belongs to the NlpA lipoprotein family
I7V34_12760	COG2011	ABC-type metal ion transport system permease component
I7V34_12765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I7V34_12775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_12780	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
I7V34_12790	COG0509	glycine decarboxylation via glycine cleavage system
I7V34_12795	COG1393	Belongs to the ArsC family
I7V34_12805	COG4221	oxidoreductase activity
I7V34_12810	COG1960	acyl-CoA dehydrogenase activity
I7V34_12815	COG0183	Belongs to the thiolase family
I7V34_12820	COG1024	Enoyl-CoA hydratase
I7V34_12820	COG1250	3-hydroxyacyl-CoA dehydrogenase
I7V34_12830	COG2364	Membrane
I7V34_12835	COG0385	Bile acid
I7V34_12845	COG0506	proline dehydrogenase activity
I7V34_12855	COG5577	PFAM Coat F domain
I7V34_12870	COG1120	ATPase activity
I7V34_12875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I7V34_12880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I7V34_12885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I7V34_12905	COG0673	inositol 2-dehydrogenase activity
I7V34_12910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_12930	COG1785	Belongs to the alkaline phosphatase family
I7V34_12935	COG1834	amidinotransferase
I7V34_12950	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_12965	COG0655	NAD(P)H dehydrogenase (quinone) activity
I7V34_12975	COG1764	response to oxidative stress
I7V34_12990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I7V34_13000	COG2514	catechol 2,3-dioxygenase activity
I7V34_13005	COG2259	Doxx family
I7V34_13010	COG1733	regulation of RNA biosynthetic process
I7V34_13030	COG1082	Xylose isomerase domain protein TIM barrel
I7V34_13060	COG0076	glutamate decarboxylase activity
I7V34_13070	COG2271	Major facilitator Superfamily
I7V34_13075	COG2814	Major facilitator Superfamily
I7V34_13090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I7V34_13100	COG1309	transcriptional regulator
I7V34_13120	COG2304	oxidoreductase activity
I7V34_13150	COG1733	regulation of RNA biosynthetic process
I7V34_13160	COG3403	YqcI/YcgG family
I7V34_13165	COG1280	lysine exporter protein (LysE YggA)
I7V34_13170	COG5577	PFAM Coat F domain
I7V34_13180	COG1309	transcriptional regulator
I7V34_13185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
I7V34_13190	COG1845	cytochrome c oxidase, subunit III
I7V34_13220	COG1027	Aspartate ammonia-lyase
I7V34_13225	COG1388	LysM domain
I7V34_13225	COG0791	NLP P60 protein
I7V34_13230	COG3842	ATPase activity
I7V34_13240	COG1840	ABC-type Fe3 transport system, periplasmic component
I7V34_13250	COG0640	Transcriptional regulator
I7V34_13255	COG1612	heme a metabolic process
I7V34_13275	COG3192	ethanolamine utilization protein
I7V34_13280	COG0006	proline dipeptidase activity
I7V34_13285	COG3290	protein histidine kinase activity
I7V34_13285	COG3829	transcription factor binding
I7V34_13290	COG1114	Component of the transport system for branched-chain amino acids
I7V34_13295	COG2186	Transcriptional regulator
I7V34_13310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
I7V34_13315	COG0557	exoribonuclease II activity
I7V34_13320	COG1647	Serine aminopeptidase, S33
I7V34_13325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I7V34_13330	COG0148	phosphopyruvate hydratase activity
I7V34_13365	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
I7V34_13385	COG5002	protein histidine kinase activity
I7V34_13390	COG0745	RESPONSE REGULATOR receiver
I7V34_13410	COG3706	GGDEF domain
I7V34_13415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_13425	COG0391	Required for morphogenesis under gluconeogenic growth conditions
I7V34_13430	COG1660	Displays ATPase and GTPase activities
I7V34_13435	COG1051	belongs to the nudix hydrolase family
I7V34_13455	COG0492	ferredoxin-NADP+ reductase activity
I7V34_13460	COG0457	Tetratricopeptide repeat
I7V34_13465	COG0140	phosphoribosyl-ATP diphosphatase activity
I7V34_13465	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
I7V34_13470	COG0107	imidazoleglycerol-phosphate synthase activity
I7V34_13475	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
I7V34_13480	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
I7V34_13485	COG0131	Imidazoleglycerol-phosphate dehydratase
I7V34_13490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
I7V34_13500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
I7V34_13505	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
I7V34_13510	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
I7V34_13515	COG0110	maltose O-acetyltransferase activity
I7V34_13520	COG0546	phosphoglycolate phosphatase activity
I7V34_13525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
I7V34_13530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
I7V34_13535	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
I7V34_13545	COG1950	PFAM Membrane protein of
I7V34_13550	COG1983	PspC domain protein
I7V34_13555	COG3595	metallopeptidase activity
I7V34_13575	COG1136	(ABC) transporter
I7V34_13585	COG1464	Belongs to the NlpA lipoprotein family
I7V34_13590	COG2011	ABC-type metal ion transport system permease component
I7V34_13600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
I7V34_13605	COG0556	nucleotide-excision repair
I7V34_13610	COG4897	Protein conserved in bacteria
I7V34_13620	COG0596	Alpha beta hydrolase
I7V34_13625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I7V34_13650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I7V34_13655	COG0569	domain protein
I7V34_13680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_13680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_13685	COG1301	dicarboxylic acid transport
I7V34_13690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I7V34_13695	COG3243	poly(R)-hydroxyalkanoic acid synthase
I7V34_13705	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_13710	COG0793	Belongs to the peptidase S41A family
I7V34_13710	COG3409	Peptidoglycan-binding domain 1 protein
I7V34_13715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
I7V34_13725	COG0626	cystathionine gamma-synthase activity
I7V34_13735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_13750	COG0745	RESPONSE REGULATOR receiver
I7V34_13755	COG0785	Cytochrome C biogenesis protein
I7V34_13770	COG0739	heme binding
I7V34_13775	COG2177	Part of the ABC transporter FtsEX involved in
I7V34_13780	COG2884	Cell division ATP-binding protein ftsE
I7V34_13785	COG2010	Cytochrome c
I7V34_13790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_13800	COG0653	protein targeting
I7V34_13805	COG1405	negative regulation of cell septum assembly
I7V34_13805	COG3012	SEC-C Motif Domain Protein
I7V34_13845	COG1516	flagellar protein fliS
I7V34_13850	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
I7V34_13855	COG1334	flagellar protein FlaG
I7V34_13860	COG5492	domain, Protein
I7V34_13860	COG4932	domain protein
I7V34_13870	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
I7V34_13875	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
I7V34_13885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
I7V34_13890	COG1256	bacterial-type flagellum assembly
I7V34_13890	COG4786	Flagellar basal body rod
I7V34_13910	COG1040	competence protein
I7V34_13915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
I7V34_13925	COG1307	EDD domain protein, DegV family
I7V34_13935	COG0737	Belongs to the 5'-nucleotidase family
I7V34_13945	COG0812	UDP-N-acetylmuramate dehydrogenase activity
I7V34_13990	COG0346	lactoylglutathione lyase activity
I7V34_14000	COG1227	inorganic diphosphatase activity
I7V34_14020	COG0768	penicillin binding
I7V34_14030	COG0737	Belongs to the 5'-nucleotidase family
I7V34_14035	COG1404	Belongs to the peptidase S8 family
I7V34_14050	COG1175	transmembrane transport
I7V34_14055	COG3842	ATPase activity
I7V34_14065	COG2011	ABC-type metal ion transport system permease component
I7V34_14070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I7V34_14095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I7V34_14120	COG1999	signal sequence binding
I7V34_14180	COG0366	Alpha amylase catalytic
I7V34_14190	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
I7V34_14205	COG2188	Transcriptional regulator
I7V34_14220	COG0579	oxidoreductase
I7V34_14240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I7V34_14245	COG0673	inositol 2-dehydrogenase activity
I7V34_14260	COG3458	cephalosporin-C deacetylase activity
I7V34_14270	COG0673	inositol 2-dehydrogenase activity
I7V34_14275	COG0673	inositol 2-dehydrogenase activity
I7V34_14305	COG0395	ABC-type sugar transport system, permease component
I7V34_14315	COG1653	transport
I7V34_14320	COG5578	integral membrane protein
I7V34_14350	COG0395	ABC-type sugar transport system, permease component
I7V34_14355	COG1175	transmembrane transport
I7V34_14360	COG1653	transport
I7V34_14365	COG1737	Transcriptional regulator
I7V34_14385	COG0681	Belongs to the peptidase S26 family
I7V34_14395	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I7V34_14405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I7V34_14415	COG2814	Major facilitator Superfamily
I7V34_14425	COG0791	NLP P60 protein
I7V34_14425	COG1388	LysM domain
I7V34_14430	COG5002	protein histidine kinase activity
I7V34_14460	COG4187	Peptidase family M20/M25/M40
I7V34_14465	COG0436	Aminotransferase
I7V34_14470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
I7V34_14470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
I7V34_14480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I7V34_14485	COG1802	Transcriptional regulator
I7V34_14490	COG0277	FAD linked oxidase domain protein
I7V34_14500	COG1595	DNA-templated transcription, initiation
I7V34_14560	COG1621	beta-fructofuranosidase activity
I7V34_14565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I7V34_14565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I7V34_14565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_14570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_14570	COG3711	transcriptional antiterminator
I7V34_14580	COG1929	Belongs to the glycerate kinase type-1 family
I7V34_14590	COG0383	alpha-mannosidase activity
I7V34_14595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I7V34_14605	COG1482	cell wall glycoprotein biosynthetic process
I7V34_14615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I7V34_14620	COG1940	carbohydrate kinase activity
I7V34_14625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I7V34_14635	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
I7V34_14640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I7V34_14645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
I7V34_14650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I7V34_14655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
I7V34_14725	COG0471	metal ion transport
I7V34_14830	COG0110	maltose O-acetyltransferase activity
I7V34_14835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
I7V34_14845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
I7V34_14865	COG1216	Glycosyl transferase, family 2
I7V34_14880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
I7V34_14890	COG4464	protein tyrosine phosphatase activity
I7V34_14895	COG0489	protein tyrosine kinase activity
I7V34_14900	COG3944	biosynthesis protein
I7V34_14910	COG1316	TRANSCRIPTIONal
I7V34_14920	COG1388	LysM domain
I7V34_14920	COG0791	NLP P60 protein
I7V34_14925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_14925	COG1263	PTS System
I7V34_14930	COG0366	Alpha amylase catalytic
I7V34_14945	COG2188	Transcriptional regulator
I7V34_14950	COG2197	response regulator
I7V34_14955	COG4585	Histidine kinase
I7V34_14960	COG1739	Uncharacterized protein family UPF0029
I7V34_14965	COG1316	TRANSCRIPTIONal
I7V34_14975	COG3307	-O-antigen
I7V34_14980	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
I7V34_15020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I7V34_15025	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_15025	COG2247	cell wall binding repeat
I7V34_15030	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_15030	COG2247	cell wall binding repeat
I7V34_15035	COG2385	sporulation resulting in formation of a cellular spore
I7V34_15035	COG2247	cell wall binding repeat
I7V34_15060	COG0438	transferase activity, transferring glycosyl groups
I7V34_15100	COG2247	cell wall binding repeat
I7V34_15100	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_15105	COG0791	NLP P60 protein
I7V34_15105	COG1388	LysM domain
I7V34_15130	COG1595	DNA-templated transcription, initiation
I7V34_15135	COG0010	Belongs to the arginase family
I7V34_15140	COG1228	amidohydrolase
I7V34_15145	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
I7V34_15150	COG2986	histidine ammonia-lyase
I7V34_15185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I7V34_15190	COG1785	Belongs to the alkaline phosphatase family
I7V34_15195	COG4715	Zinc finger, swim domain protein
I7V34_15200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I7V34_15210	COG0629	single-stranded DNA binding
I7V34_15220	COG1396	sequence-specific DNA binding
I7V34_15240	COG3764	Sortase (surface protein transpeptidase)
I7V34_15265	COG4786	Flagellar basal body rod
I7V34_15270	COG4786	Flagellar basal body rod
I7V34_15275	COG1077	Cell shape determining protein MreB Mrl
I7V34_15280	COG1609	Transcriptional regulator
I7V34_15285	COG2176	DNA-directed DNA polymerase activity
I7V34_15285	COG5002	protein histidine kinase activity
I7V34_15290	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
I7V34_15295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I7V34_15310	COG0739	heme binding
I7V34_15320	COG2385	sporulation resulting in formation of a cellular spore
I7V34_15325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
I7V34_15335	COG4836	Membrane
I7V34_15350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I7V34_15365	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
I7V34_15370	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
I7V34_15375	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
I7V34_15380	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
I7V34_15385	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
I7V34_15395	COG0356	it plays a direct role in the translocation of protons across the membrane
I7V34_15410	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
I7V34_15415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
I7V34_15425	COG0698	ribose 5-phosphate isomerase
I7V34_15430	COG0840	transmembrane signaling receptor activity
I7V34_15440	COG1971	Probably functions as a manganese efflux pump
I7V34_15445	COG0009	L-threonylcarbamoyladenylate synthase
I7V34_15450	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
I7V34_15465	COG1619	proteins homologs of microcin C7 resistance protein MccF
I7V34_15475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
I7V34_15485	COG1435	thymidine kinase activity
I7V34_15495	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
I7V34_15500	COG1494	fructose-1,6-bisphosphatase
I7V34_15505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
I7V34_15510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
I7V34_15515	COG0191	fructose-bisphosphate aldolase activity
I7V34_15520	COG2204	response regulator
I7V34_15525	COG4821	SIS domain
I7V34_15530	COG0504	CTP synthase activity
I7V34_15545	COG1703	isobutyryl-CoA mutase activity
I7V34_15545	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I7V34_15545	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I7V34_15555	COG1960	acyl-CoA dehydrogenase activity
I7V34_15560	COG1960	acyl-CoA dehydrogenase activity
I7V34_15565	COG1250	3-hydroxyacyl-CoA dehydrogenase
I7V34_15570	COG0183	Belongs to the thiolase family
I7V34_15575	COG0247	lactate metabolic process
I7V34_15575	COG2181	nitrate reductase activity
I7V34_15580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I7V34_15605	COG0018	arginyl-trna synthetase
I7V34_15610	COG4506	Protein conserved in bacteria
I7V34_15620	COG0010	Belongs to the arginase family
I7V34_15625	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
I7V34_15630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I7V34_15655	COG1994	Peptidase M50
I7V34_15670	COG3465	dGTPase activity
I7V34_15675	COG1078	dGTPase activity
I7V34_15690	COG4473	ABC transporter
I7V34_15695	COG1131	(ABC) transporter
I7V34_15700	COG0450	alkyl hydroperoxide reductase
I7V34_15705	COG0095	Lipoate-protein ligase
I7V34_15710	COG0280	phosphate acetyltransferase
I7V34_15720	COG1388	LysM domain
I7V34_15720	COG1705	Flagellar rod assembly protein muramidase FlgJ
I7V34_15725	COG3773	Cell wall hydrolase
I7V34_15740	COG2363	Small membrane protein
I7V34_15755	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
I7V34_15770	COG0351	phosphomethylpyrimidine kinase
I7V34_15775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I7V34_15785	COG1131	(ABC) transporter
I7V34_15830	COG2133	pyrroloquinoline quinone binding
I7V34_15835	COG0561	phosphatase activity
I7V34_15845	COG2031	fatty acid transporter
I7V34_15850	COG3314	Sporulation integral membrane protein YlbJ
I7V34_15855	COG2244	polysaccharide biosynthetic process
I7V34_15860	COG4191	Histidine kinase
I7V34_15870	COG0156	8-amino-7-oxononanoate synthase activity
I7V34_15890	COG2318	DinB family
I7V34_15895	COG2364	Membrane
I7V34_15905	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
I7V34_15910	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_15915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
I7V34_15920	COG2076	Multidrug Resistance protein
I7V34_15925	COG2076	Multidrug Resistance protein
I7V34_15930	COG0446	pyridine nucleotide-disulphide oxidoreductase
I7V34_15935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I7V34_15935	COG0723	plastoquinol--plastocyanin reductase activity
I7V34_15945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I7V34_15945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I7V34_15950	COG0596	Alpha beta hydrolase
I7V34_16085	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_16090	COG2610	gluconate transmembrane transporter activity
I7V34_16095	COG0583	DNA-binding transcription factor activity
I7V34_16105	COG1562	ergosterol biosynthetic process
I7V34_16130	COG0673	inositol 2-dehydrogenase activity
I7V34_16160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I7V34_16165	COG3314	Sporulation integral membrane protein YlbJ
I7V34_16175	COG0579	oxidoreductase
I7V34_16180	COG0584	glycerophosphoryl diester phosphodiesterase
I7V34_16185	COG0714	Associated with various cellular activities
I7V34_16215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I7V34_16220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
I7V34_16225	COG2169	Transcriptional regulator
I7V34_16235	COG1695	Transcriptional regulator
I7V34_16240	COG3402	PFAM membrane-flanked domain
I7V34_16250	COG0662	Cupin 2, conserved barrel domain protein
I7V34_16260	COG1695	Transcriptional regulator
I7V34_16275	COG1131	(ABC) transporter
I7V34_16290	COG1846	Transcriptional regulator
I7V34_16295	COG1764	response to oxidative stress
I7V34_16305	COG4682	membrane
I7V34_16340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I7V34_16365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I7V34_16370	COG2814	Major facilitator Superfamily
I7V34_16375	COG0667	Aldo Keto reductase
I7V34_16380	COG0673	inositol 2-dehydrogenase activity
I7V34_16385	COG1113	amino acid transport
I7V34_16405	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
I7V34_16415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I7V34_16420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
I7V34_16430	COG4863	YycH protein
I7V34_16435	COG5002	protein histidine kinase activity
I7V34_16440	COG0745	RESPONSE REGULATOR receiver
I7V34_16485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I7V34_16490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
I7V34_16495	COG1132	(ABC) transporter
I7V34_16500	COG0305	Participates in initiation and elongation during chromosome replication
I7V34_16505	COG0359	binds to the 23S rRNA
I7V34_16510	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
I7V34_16515	COG4241	membrane
I7V34_16520	COG0840	transmembrane signaling receptor activity
I7V34_16525	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
I7V34_16535	COG0360	Binds together with S18 to 16S ribosomal RNA
I7V34_16540	COG0012	GTP binding
I7V34_16545	COG4481	Protein conserved in bacteria
I7V34_16550	COG0668	transmembrane transport
I7V34_16565	COG1475	DNA binding
I7V34_16570	COG1192	Involved in chromosome partitioning
I7V34_16585	COG1475	DNA binding
I7V34_16590	COG0357	Ribosomal RNA small subunit methyltransferase G
I7V34_16600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
I7V34_16605	COG1847	R3H domain protein
I7V34_16615	COG0594	ribonuclease P activity
I7V34_16625	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
I7V34_16630	COG0592	DNA-directed DNA polymerase activity
I7V34_16635	COG2501	S4 domain
I7V34_16640	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
I7V34_16650	COG0187	DNA topoisomerase II activity
I7V34_16655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I7V34_16690	COG0386	Belongs to the glutathione peroxidase family
I7V34_16700	COG0517	IMP dehydrogenase activity
I7V34_16700	COG0516	GMP reductase activity
I7V34_16715	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
I7V34_16720	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
I7V34_16735	COG1428	Deoxynucleoside kinase
I7V34_16740	COG1428	Deoxynucleoside kinase
I7V34_16750	COG3858	chitin binding
I7V34_16750	COG1388	LysM domain
I7V34_16755	COG1335	isochorismatase
I7V34_16760	COG0590	tRNA wobble adenosine to inosine editing
I7V34_16770	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
I7V34_16775	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
I7V34_16780	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
I7V34_16835	COG1982	Orn Lys Arg decarboxylase major
I7V34_16845	COG3870	Protein conserved in bacteria
I7V34_16850	COG1728	Protein conserved in bacteria
I7V34_16855	COG0470	DNA polymerase III
I7V34_16860	COG1774	PSP1 C-terminal conserved region
I7V34_16865	COG4467	Involved in initiation control of chromosome replication
I7V34_16870	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
I7V34_16875	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
I7V34_16880	COG2002	toxin-antitoxin pair type II binding
I7V34_16890	COG0084	hydrolase, TatD family'
I7V34_16895	COG3583	domain protein
I7V34_16895	COG3584	3D domain protein
I7V34_16915	COG4466	Protein conserved in bacteria
I7V34_16930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I7V34_16935	COG0251	oxidation-reduction process
I7V34_16970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
I7V34_16975	COG2002	toxin-antitoxin pair type II binding
I7V34_16980	COG2244	polysaccharide biosynthetic process
I7V34_16985	COG3956	TIGRFAM MazG family protein
I7V34_16990	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I7V34_17005	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
I7V34_17010	COG1098	S1 RNA binding domain
I7V34_17030	COG2208	phosphoserine phosphatase activity
I7V34_17035	COG2304	oxidoreductase activity
I7V34_17040	COG0515	serine threonine protein kinase
I7V34_17045	COG0037	tRNA processing
I7V34_17050	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
I7V34_17055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
I7V34_17065	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
I7V34_17070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I7V34_17075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I7V34_17080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I7V34_17085	COG0512	Glutamine amidotransferase of anthranilate synthase
I7V34_17090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I7V34_17095	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
I7V34_17100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I7V34_17105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I7V34_17110	COG1396	sequence-specific DNA binding
I7V34_17200	COG3880	PFAM UvrB UvrC protein
I7V34_17205	COG3869	Catalyzes the specific phosphorylation of arginine residues in
I7V34_17210	COG0542	response to heat
I7V34_17215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
I7V34_17220	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
I7V34_17225	COG4956	integral membrane protein (PIN domain superfamily)
I7V34_17240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
I7V34_17245	COG1045	serine acetyltransferase
I7V34_17250	COG0215	cysteine-tRNA ligase activity
I7V34_17260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I7V34_17265	COG3688	RNA-binding protein containing a PIN domain
I7V34_17275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
I7V34_17280	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I7V34_17285	COG0250	Participates in transcription elongation, termination and antitermination
I7V34_17290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
I7V34_17295	COG0081	regulation of translation
I7V34_17300	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
I7V34_17305	COG0222	ribosome binding
I7V34_17310	COG2813	Specifically methylates the guanine in position
I7V34_17315	COG0085	RNA polymerase activity
I7V34_17325	COG1358	cellular component organization or biogenesis
I7V34_17330	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
I7V34_17335	COG0049	tRNA binding
I7V34_17340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
I7V34_17345	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
I7V34_17355	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
I7V34_17360	COG0088	Forms part of the polypeptide exit tunnel
I7V34_17370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
I7V34_17375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
I7V34_17380	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
I7V34_17385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
I7V34_17390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
I7V34_17395	COG0255	Belongs to the universal ribosomal protein uL29 family
I7V34_17400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
I7V34_17405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
I7V34_17415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
I7V34_17420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
I7V34_17430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
I7V34_17435	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
I7V34_17440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
I7V34_17445	COG1841	ribosomal large subunit assembly
I7V34_17455	COG0201	protein transport
I7V34_17460	COG0563	adenylate kinase activity
I7V34_17465	COG0024	Methionine aminopeptidase
I7V34_17470	COG2163	COG2163 Ribosomal protein L14E L6E L27E
I7V34_17475	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
I7V34_17480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
I7V34_17485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
I7V34_17495	COG0202	RNA polymerase activity
I7V34_17500	COG0203	ribosomal protein L17
I7V34_17505	COG1122	ATPase activity
I7V34_17510	COG1122	ATPase activity
I7V34_17515	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
I7V34_17520	COG0101	tRNA pseudouridine synthase activity
I7V34_17525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
I7V34_17530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
I7V34_17550	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_17555	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_17560	COG0489	protein tyrosine kinase activity
I7V34_17570	COG2194	sulfuric ester hydrolase activity
I7V34_17575	COG0726	polysaccharide deacetylase
I7V34_17660	COG1595	DNA-templated transcription, initiation
I7V34_17665	COG5662	AntiSigma factor
I7V34_17670	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
I7V34_17675	COG4856	YbbR-like protein
I7V34_17680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I7V34_17685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
I7V34_17695	COG3403	YqcI/YcgG family
I7V34_17710	COG2340	Cysteine-rich secretory protein family
I7V34_17745	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_17755	COG2814	Major facilitator Superfamily
I7V34_17775	COG4585	Histidine kinase
I7V34_17780	COG2197	response regulator
I7V34_17785	COG1131	(ABC) transporter
I7V34_17800	COG1115	amino acid carrier protein
I7V34_17810	COG0517	IMP dehydrogenase activity
I7V34_17815	COG2340	Cysteine-rich secretory protein family
I7V34_17825	COG1597	lipid kinase activity
I7V34_17830	COG1238	metal cluster binding
I7V34_17835	COG0018	arginyl-trna synthetase
I7V34_17840	COG0772	Belongs to the SEDS family
I7V34_17855	COG0398	Pfam SNARE associated Golgi protein
I7V34_17865	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
I7V34_17870	COG1181	Belongs to the D-alanine--D-alanine ligase family
I7V34_17875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I7V34_17885	COG0513	Belongs to the DEAD box helicase family
I7V34_17895	COG4294	response to UV
I7V34_17900	COG3402	PFAM membrane-flanked domain
I7V34_17905	COG3428	Bacterial PH domain
I7V34_17910	COG0705	Rhomboid family
I7V34_17915	COG0736	holo-[acyl-carrier-protein] synthase activity
I7V34_17920	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
I7V34_17930	COG0864	Transcriptional regulator
I7V34_17935	COG2337	Toxic component of a toxin-antitoxin (TA) module
I7V34_17940	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_17945	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_17950	COG2172	sigma factor antagonist activity
I7V34_17955	COG2208	phosphoserine phosphatase activity
I7V34_17960	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_17965	COG2172	sigma factor antagonist activity
I7V34_17970	COG1191	sigma factor activity
I7V34_17975	COG2208	phosphoserine phosphatase activity
I7V34_17980	COG2183	response to ionizing radiation
I7V34_17990	COG3091	SprT-like family
I7V34_18075	COG0802	atpase or kinase
I7V34_18080	COG1214	PFAM Peptidase M22, glycoprotease
I7V34_18085	COG0456	acetyltransferase
I7V34_18095	COG0488	(ABC) transporter
I7V34_18100	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
I7V34_18105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
I7V34_18110	COG0805	protein transport
I7V34_18120	COG1266	CAAX protease self-immunity
I7V34_18130	COG0459	protein refolding
I7V34_18135	COG0582	viral genome integration into host DNA
I7V34_18210	COG1846	Transcriptional regulator
I7V34_18215	COG2814	Major facilitator Superfamily
I7V34_18235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
I7V34_18270	COG2304	oxidoreductase activity
I7V34_18345	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
I7V34_18360	COG0714	Associated with various cellular activities
I7V34_18365	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
I7V34_18370	COG1305	Transglutaminase-like
I7V34_18375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
I7V34_18375	COG0519	Catalyzes the synthesis of GMP from XMP
I7V34_18380	COG2252	PERMEase
I7V34_18385	COG3711	transcriptional antiterminator
I7V34_18390	COG1263	PTS System
I7V34_18390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_18390	COG2190	(PTS) system
I7V34_18415	COG2814	Major facilitator Superfamily
I7V34_18420	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
I7V34_18430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
I7V34_18435	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
I7V34_18440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I7V34_18445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
I7V34_18450	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
I7V34_18455	COG0047	phosphoribosylformylglycinamidine synthase activity
I7V34_18465	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
I7V34_18475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I7V34_18485	COG0151	Belongs to the GarS family
I7V34_18500	COG1470	cell adhesion involved in biofilm formation
I7V34_18505	COG4496	protein, YerC YecD
I7V34_18510	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
I7V34_18515	COG0210	DNA helicase
I7V34_18520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
I7V34_18525	COG4851	CamS sex pheromone cAM373 precursor
I7V34_18535	COG2224	Isocitrate lyase
I7V34_18540	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
I7V34_18545	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
I7V34_18550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
I7V34_18560	COG0505	Belongs to the CarA family
I7V34_18565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
I7V34_18570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
I7V34_18575	COG2304	oxidoreductase activity
I7V34_18585	COG5506	Protein of unknown function (DUF1694)
I7V34_18595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
I7V34_18600	COG0154	amidase activity
I7V34_18650	COG1597	lipid kinase activity
I7V34_18680	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
I7V34_18690	COG0166	Belongs to the GPI family
I7V34_18695	COG4895	conserved protein (DUF2196)
I7V34_18700	COG1914	H( )-stimulated, divalent metal cation uptake system
I7V34_18705	COG1984	allophanate hydrolase subunit 2
I7V34_18710	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
I7V34_18715	COG2814	Major facilitator Superfamily
I7V34_18725	COG1595	DNA-templated transcription, initiation
I7V34_18735	COG1131	(ABC) transporter
I7V34_18740	COG1725	Transcriptional regulator
I7V34_18745	COG4555	ABC transporter
I7V34_18775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_18785	COG3859	Proton-coupled thiamine transporter YuaJ
I7V34_18790	COG2966	Psort location CytoplasmicMembrane, score
I7V34_18795	COG3610	response to peptide
I7V34_18805	COG1132	(ABC) transporter
I7V34_18810	COG1132	(ABC) transporter
I7V34_18815	COG3871	stress protein (general stress protein 26)
I7V34_18825	COG2323	membrane
I7V34_18835	COG1115	amino acid carrier protein
I7V34_18840	COG1960	acyl-CoA dehydrogenase activity
I7V34_18855	COG0584	glycerophosphoryl diester phosphodiesterase
I7V34_18880	COG2193	ferroxidase activity
I7V34_18890	COG1404	Belongs to the peptidase S8 family
I7V34_18895	COG2032	superoxide dismutase activity
I7V34_18900	COG0733	neurotransmitter:sodium symporter activity
I7V34_18905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I7V34_18910	COG0488	(ABC) transporter
I7V34_18920	COG3396	Phenylacetate-CoA oxygenase
I7V34_18945	COG1024	Enoyl-CoA hydratase
I7V34_18950	COG1024	Enoyl-CoA hydratase
I7V34_18955	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_18960	COG1250	3-hydroxyacyl-CoA dehydrogenase
I7V34_18965	COG0183	Belongs to the thiolase family
I7V34_18975	COG3327	negative regulation of DNA-templated transcription, initiation
I7V34_18980	COG2070	2-Nitropropane dioxygenase
I7V34_18990	COG4120	Belongs to the binding-protein-dependent transport system permease family
I7V34_18995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I7V34_19015	COG0022	dehydrogenase e1 component
I7V34_19030	COG3185	4-Hydroxyphenylpyruvate dioxygenase
I7V34_19035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
I7V34_19040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I7V34_19045	COG0179	Fumarylacetoacetate (FAA) hydrolase
I7V34_19055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I7V34_19060	COG0129	dihydroxy-acid dehydratase activity
I7V34_19065	COG0028	Belongs to the TPP enzyme family
I7V34_19070	COG0440	acetolactate synthase activity
I7V34_19075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
I7V34_19080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I7V34_19095	COG0066	3-isopropylmalate dehydratase activity
I7V34_19100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I7V34_19105	COG0460	homoserine dehydrogenase
I7V34_19110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
I7V34_19115	COG0083	homoserine kinase activity
I7V34_19130	COG5002	protein histidine kinase activity
I7V34_19155	COG0210	DNA helicase
I7V34_19175	COG1737	Transcriptional regulator
I7V34_19180	COG2610	gluconate transmembrane transporter activity
I7V34_19185	COG1070	Carbohydrate kinase
I7V34_19210	COG2249	NAD(P)H dehydrogenase (quinone) activity
I7V34_19220	COG1968	undecaprenyl-diphosphatase activity
I7V34_19240	COG1309	transcriptional regulator
I7V34_19245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I7V34_19250	COG2244	polysaccharide biosynthetic process
I7V34_19295	COG4585	Histidine kinase
I7V34_19300	COG2197	response regulator
I7V34_19335	COG1714	RDD family
I7V34_19345	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_19350	COG2130	NADP-dependent
I7V34_19365	COG0456	acetyltransferase
I7V34_19370	COG2814	Major facilitator Superfamily
I7V34_19385	COG0288	reversible hydration of carbon dioxide
I7V34_19400	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
I7V34_19410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_19420	COG0488	(ABC) transporter
I7V34_19425	COG2720	vancomycin resistance protein
I7V34_19435	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
I7V34_19445	COG2861	carbohydrate metabolic process
I7V34_19450	COG1473	amidohydrolase
I7V34_19455	COG1757	Na H antiporter
I7V34_19495	COG1595	DNA-templated transcription, initiation
I7V34_19500	COG1077	Cell shape determining protein MreB Mrl
I7V34_19505	COG0840	transmembrane signaling receptor activity
I7V34_19510	COG1744	ABC transporter substrate-binding protein PnrA-like
I7V34_19515	COG1607	acyl-coa hydrolase
I7V34_19520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I7V34_19540	COG2309	aminopeptidase activity
I7V34_19550	COG1959	2 iron, 2 sulfur cluster binding
I7V34_19595	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
I7V34_19600	COG1360	Flagellar Motor Protein
I7V34_19605	COG1115	amino acid carrier protein
I7V34_19610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I7V34_19615	COG2313	pseudouridylate synthase activity
I7V34_19620	COG5002	protein histidine kinase activity
I7V34_19625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I7V34_19630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
I7V34_19635	COG3486	L-lysine 6-monooxygenase (NADPH) activity
I7V34_19640	COG0693	protein deglycase activity
I7V34_19645	COG4840	Belongs to the UPF0435 family
I7V34_19655	COG1295	ribonuclease BN
I7V34_19660	COG3275	phosphorelay sensor kinase activity
I7V34_19665	COG3279	Response regulator of the LytR AlgR family
I7V34_19670	COG0584	glycerophosphoryl diester phosphodiesterase
I7V34_19680	COG1966	Carbon starvation protein
I7V34_19695	COG1595	DNA-templated transcription, initiation
I7V34_19710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
I7V34_19735	COG0069	glutamate synthase activity
I7V34_19745	COG1845	cytochrome c oxidase, subunit III
I7V34_19755	COG2010	Cytochrome c
I7V34_19755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I7V34_19760	COG0028	Belongs to the TPP enzyme family
I7V34_19770	COG2267	carboxylic ester hydrolase activity
I7V34_19795	COG1263	PTS System
I7V34_19795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_19795	COG2190	(PTS) system
I7V34_19805	COG2323	membrane
I7V34_19815	COG0778	Nitroreductase
I7V34_19820	COG1846	Transcriptional regulator
I7V34_19825	COG1733	regulation of RNA biosynthetic process
I7V34_19830	COG2814	Major facilitator Superfamily
I7V34_19850	COG2217	Heavy metal translocating P-type atpase
I7V34_19855	COG0477	Major facilitator Superfamily
I7V34_19865	COG3871	stress protein (general stress protein 26)
I7V34_19870	COG0387	Pfam Sodium calcium exchanger
I7V34_19890	COG0535	radical SAM domain protein
I7V34_19910	COG0494	nUDIX hydrolase
I7V34_19935	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
I7V34_19940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
I7V34_19955	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
I7V34_19965	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
I7V34_20015	COG0653	protein targeting
I7V34_20040	COG2132	Multicopper oxidase
I7V34_20060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_20060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_20065	COG1309	transcriptional regulator
I7V34_20080	COG3773	Cell wall hydrolase
I7V34_20095	COG2259	Doxx family
I7V34_20105	COG1902	pentaerythritol trinitrate reductase activity
I7V34_20110	COG0861	Integral membrane protein TerC family
I7V34_20115	COG0488	(ABC) transporter
I7V34_20120	COG4912	Dna alkylation repair
I7V34_20130	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_20140	COG1131	(ABC) transporter
I7V34_20155	COG3634	alkyl hydroperoxide reductase activity
I7V34_20160	COG0450	alkyl hydroperoxide reductase
I7V34_20165	COG0019	diaminopimelate decarboxylase activity
I7V34_20170	COG0456	acetyltransferase
I7V34_20180	COG1280	lysine exporter protein (LysE YggA)
I7V34_20210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I7V34_20235	COG0697	spore germination
I7V34_20245	COG3655	Transcriptional regulator
I7V34_20250	COG3739	integral membrane protein
I7V34_20285	COG2706	6-phosphogluconolactonase activity
I7V34_20290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_20295	COG1063	alcohol dehydrogenase
I7V34_20315	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
I7V34_20360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I7V34_20365	COG1802	Transcriptional regulator
I7V34_20370	COG2084	Dehydrogenase
I7V34_20380	COG2610	gluconate transmembrane transporter activity
I7V34_20400	COG0456	acetyltransferase
I7V34_20405	COG2304	oxidoreductase activity
I7V34_20415	COG4336	lyase activity
I7V34_20420	COG2746	aminoglycoside 3-N-acetyltransferase activity
I7V34_20435	COG0745	RESPONSE REGULATOR receiver
I7V34_20440	COG3850	Histidine kinase
I7V34_20440	COG5002	protein histidine kinase activity
I7V34_20445	COG1136	(ABC) transporter
I7V34_20460	COG0477	Major facilitator Superfamily
I7V34_20550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_20555	COG2822	iron ion transport
I7V34_20560	COG2837	iron assimilation
I7V34_20565	COG0672	)-iron permease
I7V34_20575	COG2814	Major facilitator Superfamily
I7V34_20595	COG0395	ABC-type sugar transport system, permease component
I7V34_20605	COG2723	6-phospho-beta-galactosidase activity
I7V34_20635	COG0730	response to heat
I7V34_20640	COG4221	oxidoreductase activity
I7V34_20645	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_20670	COG0745	RESPONSE REGULATOR receiver
I7V34_20675	COG2205	protein histidine kinase activity
I7V34_20680	COG1388	LysM domain
I7V34_20690	COG0861	Integral membrane protein TerC family
I7V34_20725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
I7V34_20730	COG0254	rRNA binding
I7V34_20745	COG2814	Major facilitator Superfamily
I7V34_20750	COG1309	transcriptional regulator
I7V34_20755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I7V34_20765	COG3588	fructose-bisphosphate aldolase
I7V34_20770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I7V34_20785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
I7V34_20795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_20810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
I7V34_20815	COG0805	protein transport
I7V34_20820	COG3540	Alkaline phosphatase
I7V34_20845	COG1595	DNA-templated transcription, initiation
I7V34_20885	COG0572	uridine kinase
I7V34_20905	COG0456	acetyltransferase
I7V34_20905	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
I7V34_20925	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
I7V34_21030	COG1401	restriction endodeoxyribonuclease activity
I7V34_21040	COG0513	Belongs to the DEAD box helicase family
I7V34_21070	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
I7V34_21085	COG0305	Participates in initiation and elongation during chromosome replication
I7V34_21100	COG0542	response to heat
I7V34_21115	COG0697	spore germination
I7V34_21120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I7V34_21135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I7V34_21140	COG0640	Transcriptional regulator
I7V34_21155	COG1401	restriction endodeoxyribonuclease activity
I7V34_21190	COG5505	Protein of unknown function (DUF819)
I7V34_21205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_21210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I7V34_21215	COG3142	Participates in the control of copper homeostasis
I7V34_21220	COG1408	metallophosphoesterase
I7V34_21235	COG5577	PFAM Coat F domain
I7V34_21240	COG1063	alcohol dehydrogenase
I7V34_21250	COG5577	PFAM Coat F domain
I7V34_21260	COG4807	Protein conserved in bacteria
I7V34_21270	COG1136	(ABC) transporter
I7V34_21275	COG0577	efflux transmembrane transporter activity
I7V34_21285	COG5002	protein histidine kinase activity
I7V34_21290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I7V34_21295	COG1802	Transcriptional regulator
I7V34_21300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
I7V34_21305	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
I7V34_21310	COG0066	3-isopropylmalate dehydratase activity
I7V34_21320	COG4145	pantothenate transmembrane transporter activity
I7V34_21325	COG2271	Major facilitator Superfamily
I7V34_21330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I7V34_21345	COG1024	Enoyl-CoA hydratase
I7V34_21350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I7V34_21385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I7V34_21395	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_21405	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_21495	COG3708	Transcriptional regulator
I7V34_21495	COG2207	Transcriptional regulator
I7V34_21520	COG0494	nUDIX hydrolase
I7V34_21600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I7V34_21605	COG1595	DNA-templated transcription, initiation
I7V34_21625	COG1301	dicarboxylic acid transport
I7V34_21635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I7V34_21670	COG1233	COG1233 Phytoene dehydrogenase and related
I7V34_21690	COG1595	DNA-templated transcription, initiation
I7V34_21705	COG1595	DNA-templated transcription, initiation
I7V34_21735	COG2508	Transcriptional regulator
I7V34_21740	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_21745	COG0506	proline dehydrogenase activity
I7V34_21750	COG1720	tRNA m6t6A37 methyltransferase activity
I7V34_21760	COG2267	carboxylic ester hydrolase activity
I7V34_21765	COG1595	DNA-templated transcription, initiation
I7V34_21795	COG0494	nUDIX hydrolase
I7V34_21810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
I7V34_21810	COG0456	acetyltransferase
I7V34_21850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_21855	COG2188	Transcriptional regulator
I7V34_21875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_21875	COG1263	PTS System
I7V34_21880	COG1253	flavin adenine dinucleotide binding
I7V34_21885	COG0628	permease
I7V34_21890	COG1846	Transcriptional regulator
I7V34_21945	COG0346	lactoylglutathione lyase activity
I7V34_21955	COG2814	Major facilitator Superfamily
I7V34_21960	COG0671	phosphoesterase, PA-phosphatase related
I7V34_21975	COG2084	Dehydrogenase
I7V34_21980	COG0366	Alpha amylase catalytic
I7V34_22020	COG1131	(ABC) transporter
I7V34_22040	COG0501	Belongs to the peptidase M48B family
I7V34_22045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_22050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
I7V34_22055	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_22060	COG3706	GGDEF domain
I7V34_22065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I7V34_22075	COG2814	Major facilitator Superfamily
I7V34_22080	COG1309	transcriptional regulator
I7V34_22090	COG1278	Cold shock
I7V34_22130	COG3239	Fatty acid desaturase
I7V34_22135	COG0306	phosphate transporter
I7V34_22140	COG1392	Phosphate transport regulator
I7V34_22145	COG2207	Transcriptional regulator
I7V34_22145	COG3708	Transcriptional regulator
I7V34_22160	COG0789	Transcriptional regulator