locus-tag	class	description
D9C22_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9C22_00010	COG0592	DNA-directed DNA polymerase activity
D9C22_00015	COG2501	S4 domain
D9C22_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9C22_00030	COG0187	DNA topoisomerase II activity
D9C22_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C22_00070	COG0517	IMP dehydrogenase activity
D9C22_00070	COG0516	GMP reductase activity
D9C22_00075	COG1686	Belongs to the peptidase S11 family
D9C22_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D9C22_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D9C22_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D9C22_00100	COG1428	Deoxynucleoside kinase
D9C22_00105	COG1428	Deoxynucleoside kinase
D9C22_00110	COG3858	chitin binding
D9C22_00110	COG1388	LysM domain
D9C22_00115	COG1335	isochorismatase
D9C22_00120	COG0590	tRNA wobble adenosine to inosine editing
D9C22_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9C22_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9C22_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9C22_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D9C22_00190	COG3853	Toxic anion resistance protein (TelA)
D9C22_00195	COG1982	Orn Lys Arg decarboxylase major
D9C22_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9C22_00205	COG3870	Protein conserved in bacteria
D9C22_00210	COG1728	Protein conserved in bacteria
D9C22_00215	COG0470	DNA polymerase III
D9C22_00220	COG1774	PSP1 C-terminal conserved region
D9C22_00225	COG4467	Involved in initiation control of chromosome replication
D9C22_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9C22_00235	COG2827	Endonuclease containing a URI domain
D9C22_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9C22_00245	COG2002	toxin-antitoxin pair type II binding
D9C22_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C22_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C22_00255	COG0084	hydrolase, TatD family'
D9C22_00260	COG3584	3D domain protein
D9C22_00260	COG3583	domain protein
D9C22_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C22_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9C22_00280	COG4466	Protein conserved in bacteria
D9C22_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9C22_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C22_00300	COG0251	oxidation-reduction process
D9C22_00305	COG2088	sporulation resulting in formation of a cellular spore
D9C22_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9C22_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9C22_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9C22_00325	COG0193	aminoacyl-tRNA hydrolase activity
D9C22_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9C22_00340	COG2002	toxin-antitoxin pair type II binding
D9C22_00345	COG2244	polysaccharide biosynthetic process
D9C22_00350	COG3956	TIGRFAM MazG family protein
D9C22_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9C22_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D9C22_00375	COG1098	S1 RNA binding domain
D9C22_00390	COG2208	phosphoserine phosphatase activity
D9C22_00395	COG2304	oxidoreductase activity
D9C22_00400	COG0515	serine threonine protein kinase
D9C22_00405	COG0037	tRNA processing
D9C22_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9C22_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9C22_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D9C22_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C22_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C22_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C22_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
D9C22_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C22_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9C22_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9C22_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9C22_00470	COG1396	sequence-specific DNA binding
D9C22_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C22_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9C22_00560	COG4463	regulation of RNA biosynthetic process
D9C22_00565	COG3880	PFAM UvrB UvrC protein
D9C22_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D9C22_00575	COG0542	response to heat
D9C22_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9C22_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9C22_00590	COG4956	integral membrane protein (PIN domain superfamily)
D9C22_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9C22_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D9C22_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9C22_00615	COG1045	serine acetyltransferase
D9C22_00620	COG0215	cysteine-tRNA ligase activity
D9C22_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D9C22_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C22_00635	COG3688	RNA-binding protein containing a PIN domain
D9C22_00640	COG1595	DNA-templated transcription, initiation
D9C22_00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9C22_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C22_00655	COG0250	Participates in transcription elongation, termination and antitermination
D9C22_00660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D9C22_00665	COG0081	regulation of translation
D9C22_00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D9C22_00675	COG0222	ribosome binding
D9C22_00680	COG2813	Specifically methylates the guanine in position
D9C22_00685	COG0085	RNA polymerase activity
D9C22_00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9C22_00695	COG1358	cellular component organization or biogenesis
D9C22_00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9C22_00705	COG0049	tRNA binding
D9C22_00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D9C22_00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D9C22_00720	COG0596	Alpha beta hydrolase
D9C22_00725	COG0051	transcription antitermination factor activity, RNA binding
D9C22_00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9C22_00735	COG0088	Forms part of the polypeptide exit tunnel
D9C22_00740	COG0089	rRNA binding
D9C22_00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9C22_00750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D9C22_00755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D9C22_00760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9C22_00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9C22_00770	COG0255	Belongs to the universal ribosomal protein uL29 family
D9C22_00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9C22_00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D9C22_00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9C22_00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D9C22_00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9C22_00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D9C22_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9C22_00820	COG1841	ribosomal large subunit assembly
D9C22_00825	COG0200	Binds to the 23S rRNA
D9C22_00830	COG0201	protein transport
D9C22_00835	COG0563	adenylate kinase activity
D9C22_00840	COG0024	Methionine aminopeptidase
D9C22_00845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D9C22_00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9C22_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9C22_00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D9C22_00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9C22_00870	COG0202	RNA polymerase activity
D9C22_00875	COG0203	ribosomal protein L17
D9C22_00880	COG1122	ATPase activity
D9C22_00885	COG1122	ATPase activity
D9C22_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C22_00895	COG0101	tRNA pseudouridine synthase activity
D9C22_00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9C22_00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9C22_00910	COG2226	methyltransferase
D9C22_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C22_00925	COG0489	protein tyrosine kinase activity
D9C22_00935	COG2194	sulfuric ester hydrolase activity
D9C22_00940	COG0726	polysaccharide deacetylase
D9C22_01020	COG0659	secondary active sulfate transmembrane transporter activity
D9C22_01025	COG0385	Bile acid
D9C22_01030	COG2819	hydrolase of the alpha beta superfamily
D9C22_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C22_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C22_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C22_01050	COG2207	Transcriptional regulator
D9C22_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C22_01055	COG3876	Protein conserved in bacteria
D9C22_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
D9C22_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C22_01070	COG1263	PTS System
D9C22_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_01075	COG1737	Transcriptional regulator
D9C22_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9C22_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C22_01090	COG1683	Conserved Protein
D9C22_01120	COG1595	DNA-templated transcription, initiation
D9C22_01125	COG5662	AntiSigma factor
D9C22_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C22_01135	COG4856	YbbR-like protein
D9C22_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C22_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9C22_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9C22_01160	COG2169	Transcriptional regulator
D9C22_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9C22_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C22_01175	COG3002	Belongs to the UPF0753 family
D9C22_01180	COG0288	reversible hydration of carbon dioxide
D9C22_01190	COG5609	conserved protein (DUF2294)
D9C22_01195	COG0640	Transcriptional regulator
D9C22_01200	COG2814	Major facilitator Superfamily
D9C22_01215	COG0515	serine threonine protein kinase
D9C22_01230	COG1113	amino acid transport
D9C22_01245	COG2602	Beta-lactamase
D9C22_01250	COG2124	cytochrome p450
D9C22_01260	COG0531	amino acid
D9C22_01265	COG0584	glycerophosphoryl diester phosphodiesterase
D9C22_01270	COG2271	Major facilitator Superfamily
D9C22_01285	COG1846	Transcriptional regulator
D9C22_01285	COG0456	acetyltransferase
D9C22_01290	COG2271	Major facilitator Superfamily
D9C22_01300	COG3409	Peptidoglycan-binding domain 1 protein
D9C22_01305	COG0697	spore germination
D9C22_01310	COG2207	Transcriptional regulator
D9C22_01310	COG1917	Cupin 2, conserved barrel domain protein
D9C22_01315	COG1397	ADP-ribosylglycohydrolase
D9C22_01325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D9C22_01330	COG3591	Belongs to the peptidase S1B family
D9C22_01340	COG0596	Alpha beta hydrolase
D9C22_01345	COG1183	phosphatidylcholine synthase activity
D9C22_01350	COG0586	Pfam SNARE associated Golgi protein
D9C22_01355	COG0688	phosphatidylethanolamine metabolic process
D9C22_01365	COG2312	Erythromycin esterase
D9C22_01375	COG1301	dicarboxylic acid transport
D9C22_01380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_01380	COG2190	(PTS) system
D9C22_01380	COG1263	PTS System
D9C22_01385	COG0363	glucosamine-6-phosphate deaminase activity
D9C22_01400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C22_01405	COG0833	amino acid
D9C22_01410	COG2040	homocysteine
D9C22_01420	COG1115	amino acid carrier protein
D9C22_01425	COG2066	Belongs to the glutaminase family
D9C22_01430	COG4191	Histidine kinase
D9C22_01435	COG0784	Response regulator, receiver
D9C22_01440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C22_01445	COG1012	belongs to the aldehyde dehydrogenase family
D9C22_01450	COG2271	Major facilitator Superfamily
D9C22_01455	COG4948	Mandelate Racemase Muconate Lactonizing
D9C22_01460	COG2186	Transcriptional regulator
D9C22_01465	COG2721	sulfolactate sulfo-lyase activity
D9C22_01470	COG3173	Aminoglycoside phosphotransferase
D9C22_01480	COG0697	spore germination
D9C22_01485	COG0745	RESPONSE REGULATOR receiver
D9C22_01490	COG2205	protein histidine kinase activity
D9C22_01495	COG1131	(ABC) transporter
D9C22_01515	COG3773	Cell wall hydrolase
D9C22_01520	COG2304	oxidoreductase activity
D9C22_01530	COG3540	Alkaline phosphatase
D9C22_01535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C22_01540	COG0805	protein transport
D9C22_01545	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D9C22_01550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C22_01555	COG0477	Major facilitator Superfamily
D9C22_01560	COG1309	transcriptional regulator
D9C22_01565	COG0252	asparaginase activity
D9C22_01570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C22_01575	COG1714	RDD family
D9C22_01580	COG1405	negative regulation of cell septum assembly
D9C22_01580	COG3012	SEC-C Motif Domain Protein
D9C22_01585	COG3290	protein histidine kinase activity
D9C22_01590	COG3279	Response regulator of the LytR AlgR family
D9C22_01595	COG4555	ABC transporter
D9C22_01600	COG1668	transmembrane transport
D9C22_01605	COG0667	Aldo Keto reductase
D9C22_01620	COG1595	DNA-templated transcription, initiation
D9C22_01630	COG1595	DNA-templated transcription, initiation
D9C22_01635	COG1876	peptidase activity
D9C22_01640	COG0457	Tetratricopeptide repeat
D9C22_01645	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_01650	COG0366	Alpha amylase catalytic
D9C22_01655	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C22_01660	COG1121	(ABC) transporter
D9C22_01665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C22_01670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C22_01675	COG2310	stress, protein
D9C22_01680	COG2310	stress, protein
D9C22_01685	COG2310	stress, protein
D9C22_01690	COG0861	Integral membrane protein TerC family
D9C22_01700	COG3853	Toxic anion resistance protein (TelA)
D9C22_01705	COG0477	Major facilitator Superfamily
D9C22_01715	COG2814	Major facilitator Superfamily
D9C22_01720	COG0640	Transcriptional regulator
D9C22_01725	COG0517	IMP dehydrogenase activity
D9C22_01725	COG4175	Glycine betaine
D9C22_01730	COG4176	ABC-type proline glycine betaine transport system permease component
D9C22_01735	COG2113	Glycine betaine
D9C22_01740	COG1473	amidohydrolase
D9C22_01745	COG1288	antiporter activity
D9C22_01755	COG0366	Alpha amylase catalytic
D9C22_01760	COG0039	L-malate dehydrogenase activity
D9C22_01765	COG1620	l-lactate permease
D9C22_01770	COG2814	Major facilitator Superfamily
D9C22_01775	COG1846	Transcriptional regulator
D9C22_01780	COG1280	lysine exporter protein (LysE YggA)
D9C22_01785	COG3403	YqcI/YcgG family
D9C22_01790	COG1113	amino acid transport
D9C22_01795	COG3665	Urea carboxylase-associated protein
D9C22_01800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D9C22_01805	COG1660	Displays ATPase and GTPase activities
D9C22_01810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9C22_01815	COG2226	methyltransferase
D9C22_01820	COG0583	DNA-binding transcription factor activity
D9C22_01825	COG3458	cephalosporin-C deacetylase activity
D9C22_01830	COG3541	Predicted nucleotidyltransferase
D9C22_01835	COG0506	proline dehydrogenase activity
D9C22_01840	COG1012	belongs to the aldehyde dehydrogenase family
D9C22_01845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C22_01850	COG2508	Transcriptional regulator
D9C22_01855	COG3689	TIGRFAM TIGR03943 family protein
D9C22_01860	COG0701	Predicted permease
D9C22_01865	COG2267	carboxylic ester hydrolase activity
D9C22_01870	COG0492	ferredoxin-NADP+ reductase activity
D9C22_01875	COG1587	Uroporphyrinogen-III synthase
D9C22_01875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C22_01880	COG2146	nitrite reductase [NAD(P)H] activity
D9C22_01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C22_01890	COG0243	molybdopterin cofactor binding
D9C22_01895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C22_01900	COG2223	nitrite transmembrane transporter activity
D9C22_01905	COG1469	GTP cyclohydrolase I activity
D9C22_01910	COG1376	ErfK ybiS ycfS ynhG family protein
D9C22_01920	COG0523	cobalamin synthesis protein
D9C22_01925	COG0765	amino acid transport
D9C22_01930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C22_01940	COG1714	RDD family
D9C22_01950	COG2723	6-phospho-beta-galactosidase activity
D9C22_01960	COG3209	COG3209 Rhs family protein
D9C22_01965	COG3290	protein histidine kinase activity
D9C22_01965	COG0840	transmembrane signaling receptor activity
D9C22_01970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9C22_01975	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9C22_01980	COG1733	regulation of RNA biosynthetic process
D9C22_01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_02000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D9C22_02005	COG2814	Major facilitator Superfamily
D9C22_02015	COG0697	spore germination
D9C22_02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C22_02030	COG2364	Membrane
D9C22_02035	COG1126	abc transporter atp-binding protein
D9C22_02040	COG0765	amino acid transport
D9C22_02045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C22_02050	COG0583	DNA-binding transcription factor activity
D9C22_02055	COG0163	prenyltransferase activity
D9C22_02060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D9C22_02075	COG0596	Alpha beta hydrolase
D9C22_02080	COG3104	oligopeptide transport
D9C22_02085	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C22_02095	COG0697	spore germination
D9C22_02105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C22_02110	COG1136	(ABC) transporter
D9C22_02115	COG0577	efflux transmembrane transporter activity
D9C22_02120	COG0745	RESPONSE REGULATOR receiver
D9C22_02125	COG5002	protein histidine kinase activity
D9C22_02125	COG3850	Histidine kinase
D9C22_02130	COG0457	Tetratricopeptide repeat
D9C22_02150	COG0527	aspartate kinase activity
D9C22_02155	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C22_02160	COG4605	iron ion homeostasis
D9C22_02165	COG4604	ABC transporter, ATP-binding protein
D9C22_02170	COG4607	ABC-type enterochelin transport system periplasmic component
D9C22_02175	COG2814	Major facilitator Superfamily
D9C22_02180	COG1309	transcriptional regulator
D9C22_02185	COG0778	Nitroreductase
D9C22_02190	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C22_02195	COG0640	Transcriptional regulator
D9C22_02200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C22_02205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9C22_02210	COG1012	belongs to the aldehyde dehydrogenase family
D9C22_02215	COG4975	Glucose uptake
D9C22_02220	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_02225	COG4549	nuclear export factor GLE1
D9C22_02230	COG1276	copper resistance
D9C22_02230	COG2372	response to copper ion
D9C22_02235	COG1349	DNA-binding transcription factor activity
D9C22_02245	COG2213	PTS system mannitol-specific
D9C22_02250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C22_02255	COG0246	Mannitol dehydrogenase
D9C22_02260	COG0473	3-isopropylmalate dehydrogenase activity
D9C22_02265	COG0681	Belongs to the peptidase S26 family
D9C22_02270	COG0412	Dienelactone hydrolase
D9C22_02275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C22_02285	COG0561	phosphatase activity
D9C22_02290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9C22_02295	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C22_02300	COG4336	lyase activity
D9C22_02305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9C22_02310	COG1984	allophanate hydrolase subunit 2
D9C22_02330	COG2329	Antibiotic biosynthesis monooxygenase
D9C22_02340	COG4989	oxidoreductase activity
D9C22_02345	COG3711	transcriptional antiterminator
D9C22_02350	COG0318	PFAM AMP-dependent synthetase and ligase
D9C22_02355	COG2226	methyltransferase
D9C22_02360	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_02365	COG1917	Cupin 2, conserved barrel domain protein
D9C22_02370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C22_02375	COG3871	stress protein (general stress protein 26)
D9C22_02385	COG2814	Major facilitator Superfamily
D9C22_02390	COG1522	sequence-specific DNA binding
D9C22_02395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C22_02395	COG0551	DNA topoisomerase type I activity
D9C22_02400	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D9C22_02405	COG3706	GGDEF domain
D9C22_02410	COG5298	Protein conserved in bacteria
D9C22_02415	COG1215	transferase activity, transferring glycosyl groups
D9C22_02425	COG0531	amino acid
D9C22_02430	COG0494	nUDIX hydrolase
D9C22_02435	COG0028	Belongs to the TPP enzyme family
D9C22_02450	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C22_02455	COG2261	transglycosylase associated protein
D9C22_02460	COG4876	unkown
D9C22_02465	COG2217	Heavy metal translocating P-type atpase
D9C22_02470	COG3729	General stress protein
D9C22_02475	COG0662	Cupin 2, conserved barrel domain protein
D9C22_02480	COG2329	Antibiotic biosynthesis monooxygenase
D9C22_02485	COG3546	catalase activity
D9C22_02490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D9C22_02495	COG3290	protein histidine kinase activity
D9C22_02500	COG4565	transcriptional regulatory protein
D9C22_02505	COG1301	dicarboxylic acid transport
D9C22_02510	COG0628	permease
D9C22_02515	COG1131	(ABC) transporter
D9C22_02520	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C22_02530	COG1960	acyl-CoA dehydrogenase activity
D9C22_02545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C22_02550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C22_02555	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9C22_02560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9C22_02570	COG0513	Belongs to the DEAD box helicase family
D9C22_02575	COG3402	PFAM membrane-flanked domain
D9C22_02580	COG3428	Bacterial PH domain
D9C22_02585	COG0705	Rhomboid family
D9C22_02590	COG0736	holo-[acyl-carrier-protein] synthase activity
D9C22_02595	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9C22_02600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C22_02605	COG0864	Transcriptional regulator
D9C22_02610	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9C22_02615	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C22_02620	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C22_02625	COG2172	sigma factor antagonist activity
D9C22_02630	COG2208	phosphoserine phosphatase activity
D9C22_02635	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C22_02640	COG2172	sigma factor antagonist activity
D9C22_02645	COG1191	sigma factor activity
D9C22_02650	COG2208	phosphoserine phosphatase activity
D9C22_02655	COG2183	response to ionizing radiation
D9C22_02665	COG3091	SprT-like family
D9C22_02750	COG5444	nuclease activity
D9C22_02760	COG1476	TRANSCRIPTIONal
D9C22_02770	COG3239	Fatty acid desaturase
D9C22_02775	COG1278	Cold shock
D9C22_02780	COG1329	Transcriptional regulator
D9C22_02790	COG0697	spore germination
D9C22_02795	COG1917	Cupin 2, conserved barrel domain protein
D9C22_02795	COG2207	Transcriptional regulator
D9C22_02800	COG0697	spore germination
D9C22_02805	COG3708	Transcriptional regulator
D9C22_02805	COG2207	Transcriptional regulator
D9C22_02810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C22_02815	COG0477	Major facilitator Superfamily
D9C22_02825	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D9C22_02845	COG1309	transcriptional regulator
D9C22_02850	COG0697	spore germination
D9C22_02855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C22_02860	COG2030	dehydratase
D9C22_02865	COG3545	Serine hydrolase
D9C22_02870	COG1733	regulation of RNA biosynthetic process
D9C22_02875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C22_02880	COG1733	regulation of RNA biosynthetic process
D9C22_02885	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9C22_02890	COG2814	Major facilitator Superfamily
D9C22_02895	COG1309	transcriptional regulator
D9C22_02900	COG0640	Transcriptional regulator
D9C22_02905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9C22_02915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C22_02920	COG0697	spore germination
D9C22_02925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C22_02930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C22_02935	COG0640	Transcriptional regulator
D9C22_02940	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9C22_02955	COG4585	Histidine kinase
D9C22_02960	COG2197	response regulator
D9C22_02965	COG2409	Drug exporters of the RND superfamily
D9C22_02970	COG0596	Alpha beta hydrolase
D9C22_02975	COG1811	Na channel or pump
D9C22_02980	COG0789	Transcriptional regulator
D9C22_02980	COG4978	Transcriptional regulator
D9C22_02985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C22_02990	COG0778	Nitroreductase
D9C22_02995	COG0346	lactoylglutathione lyase activity
D9C22_03000	COG2259	Doxx family
D9C22_03005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C22_03025	COG2323	membrane
D9C22_03030	COG2323	membrane
D9C22_03035	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C22_03050	COG1309	transcriptional regulator
D9C22_03060	COG0456	acetyltransferase
D9C22_03070	COG1113	amino acid transport
D9C22_03075	COG2318	DinB family
D9C22_03080	COG1846	Transcriptional regulator
D9C22_03085	COG1033	growth of symbiont in host cell
D9C22_03085	COG2409	Drug exporters of the RND superfamily
D9C22_03090	COG0778	Nitroreductase
D9C22_03095	COG1846	Transcriptional regulator
D9C22_03100	COG2814	Major facilitator Superfamily
D9C22_03105	COG0730	response to heat
D9C22_03110	COG1802	Transcriptional regulator
D9C22_03115	COG1388	LysM domain
D9C22_03115	COG3858	chitin binding
D9C22_03120	COG1819	glycosyl
D9C22_03130	COG1785	Belongs to the alkaline phosphatase family
D9C22_03135	COG5646	InterPro IPR014922
D9C22_03145	COG0454	-acetyltransferase
D9C22_03150	COG1078	dGTPase activity
D9C22_03155	COG1388	LysM domain
D9C22_03160	COG2814	Major facilitator Superfamily
D9C22_03165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C22_03170	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9C22_03175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C22_03180	COG2723	6-phospho-beta-galactosidase activity
D9C22_03185	COG2188	Transcriptional regulator
D9C22_03190	COG1940	carbohydrate kinase activity
D9C22_03195	COG1482	cell wall glycoprotein biosynthetic process
D9C22_03200	COG4124	Belongs to the glycosyl hydrolase 26 family
D9C22_03245	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D9C22_03250	COG0802	atpase or kinase
D9C22_03255	COG1214	PFAM Peptidase M22, glycoprotease
D9C22_03260	COG0456	acetyltransferase
D9C22_03265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D9C22_03270	COG0488	(ABC) transporter
D9C22_03275	COG0315	cyclic pyranopterin monophosphate synthase activity
D9C22_03280	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9C22_03285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C22_03290	COG0805	protein transport
D9C22_03305	COG1266	CAAX protease self-immunity
D9C22_03310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D9C22_03315	COG0459	protein refolding
D9C22_03325	COG1073	alpha beta
D9C22_03330	COG0457	Tetratricopeptide repeat
D9C22_03335	COG1063	alcohol dehydrogenase
D9C22_03340	COG2211	Major facilitator Superfamily
D9C22_03345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C22_03350	COG1842	Phage shock protein A
D9C22_03355	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C22_03360	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D9C22_03365	COG4260	virion core protein, lumpy skin disease virus
D9C22_03375	COG2814	Major facilitator Superfamily
D9C22_03380	COG1063	alcohol dehydrogenase
D9C22_03385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D9C22_03390	COG0823	Involved in the tonB-independent uptake of proteins
D9C22_03405	COG2267	carboxylic ester hydrolase activity
D9C22_03415	COG2132	Multicopper oxidase
D9C22_03420	COG1113	amino acid transport
D9C22_03430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C22_03435	COG0714	Associated with various cellular activities
D9C22_03440	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9C22_03445	COG1305	Transglutaminase-like
D9C22_03450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9C22_03450	COG0519	Catalyzes the synthesis of GMP from XMP
D9C22_03465	COG2252	PERMEase
D9C22_03470	COG3064	Membrane
D9C22_03480	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D9C22_03490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9C22_03495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9C22_03500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9C22_03505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9C22_03510	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C22_03515	COG0047	phosphoribosylformylglycinamidine synthase activity
D9C22_03520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C22_03525	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9C22_03530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9C22_03535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9C22_03540	COG0138	bifunctional purine biosynthesis protein purh
D9C22_03545	COG0151	Belongs to the GarS family
D9C22_03550	COG1522	sequence-specific DNA binding
D9C22_03555	COG0531	amino acid
D9C22_03565	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C22_03570	COG1470	cell adhesion involved in biofilm formation
D9C22_03575	COG4496	protein, YerC YecD
D9C22_03580	COG0069	glutamate synthase activity
D9C22_03585	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D9C22_03590	COG0210	DNA helicase
D9C22_03595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9C22_03600	COG4851	CamS sex pheromone cAM373 precursor
D9C22_03605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C22_03610	COG1285	pathogenesis
D9C22_03615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C22_03620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C22_03625	COG0154	amidase activity
D9C22_03630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C22_03635	COG1309	transcriptional regulator
D9C22_03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9C22_03645	COG1597	lipid kinase activity
D9C22_03650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C22_03665	COG5444	nuclease activity
D9C22_03670	COG3391	amine dehydrogenase activity
D9C22_03675	COG0457	Tetratricopeptide repeat
D9C22_03685	COG0217	transcriptional regulatory protein
D9C22_03695	COG1309	transcriptional regulator
D9C22_03700	COG3631	Ketosteroid isomerase-related protein
D9C22_03705	COG0702	epimerase
D9C22_03720	COG3546	catalase activity
D9C22_03725	COG0454	-acetyltransferase
D9C22_03735	COG5578	integral membrane protein
D9C22_03740	COG2972	Histidine kinase
D9C22_03745	COG2207	Transcriptional regulator
D9C22_03745	COG4753	response regulator
D9C22_03750	COG1653	transport
D9C22_03755	COG1175	transmembrane transport
D9C22_03760	COG0395	ABC-type sugar transport system, permease component
D9C22_03765	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C22_03770	COG2207	Transcriptional regulator
D9C22_03775	COG2755	lipolytic protein G-D-S-L family
D9C22_03785	COG5578	integral membrane protein
D9C22_03790	COG3401	FG-GAP repeat protein
D9C22_03795	COG3401	FG-GAP repeat protein
D9C22_03800	COG2755	lipolytic protein G-D-S-L family
D9C22_03805	COG1874	Beta-galactosidase
D9C22_03815	COG1653	transport
D9C22_03820	COG4209	transmembrane transport
D9C22_03825	COG0395	ABC-type sugar transport system, permease component
D9C22_03830	COG1486	melibiose metabolic process
D9C22_03835	COG2323	membrane
D9C22_03840	COG2329	Antibiotic biosynthesis monooxygenase
D9C22_03845	COG0346	lactoylglutathione lyase activity
D9C22_03860	COG5583	Uncharacterized small protein (DUF2292)
D9C22_03865	COG0670	Belongs to the BI1 family
D9C22_03870	COG0697	spore germination
D9C22_03875	COG1846	Transcriptional regulator
D9C22_03880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9C22_03900	COG1368	sulfuric ester hydrolase activity
D9C22_03905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D9C22_03910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C22_03915	COG1442	glycosyl transferase family 8
D9C22_03920	COG1216	Glycosyl transferase, family 2
D9C22_03925	COG1442	glycosyl transferase family 8
D9C22_03930	COG2223	nitrite transmembrane transporter activity
D9C22_03935	COG1011	Hydrolase
D9C22_03940	COG0531	amino acid
D9C22_03945	COG1012	belongs to the aldehyde dehydrogenase family
D9C22_03950	COG0840	transmembrane signaling receptor activity
D9C22_03955	COG0488	(ABC) transporter
D9C22_03965	COG0789	Transcriptional regulator
D9C22_03970	COG2814	Major facilitator Superfamily
D9C22_03975	COG1404	Belongs to the peptidase S8 family
D9C22_03990	COG0488	(ABC) transporter
D9C22_03995	COG0513	Belongs to the DEAD box helicase family
D9C22_04000	COG0456	acetyltransferase
D9C22_04005	COG2130	NADP-dependent
D9C22_04010	COG1120	ATPase activity
D9C22_04015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C22_04020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C22_04025	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9C22_04040	COG3866	Pectate lyase
D9C22_04045	COG0471	metal ion transport
D9C22_04050	COG3290	protein histidine kinase activity
D9C22_04055	COG4565	transcriptional regulatory protein
D9C22_04060	COG3181	Tripartite tricarboxylate transporter family receptor
D9C22_04065	COG2851	Citrate transporter
D9C22_04070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C22_04075	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D9C22_04080	COG1254	Belongs to the acylphosphatase family
D9C22_04085	COG2258	MOSC domain
D9C22_04105	COG0024	Methionine aminopeptidase
D9C22_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_04110	COG1263	PTS System
D9C22_04115	COG1368	sulfuric ester hydrolase activity
D9C22_04130	COG1115	amino acid carrier protein
D9C22_04135	COG0531	amino acid
D9C22_04150	COG0697	spore germination
D9C22_04155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_04155	COG1263	PTS System
D9C22_04160	COG0366	Alpha amylase catalytic
D9C22_04165	COG2188	Transcriptional regulator
D9C22_04170	COG0778	Nitroreductase
D9C22_04175	COG0737	Belongs to the 5'-nucleotidase family
D9C22_04180	COG0693	protein deglycase activity
D9C22_04185	COG2814	Major facilitator Superfamily
D9C22_04190	COG4840	Belongs to the UPF0435 family
D9C22_04195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C22_04200	COG4980	gas vesicle protein
D9C22_04205	COG1295	ribonuclease BN
D9C22_04210	COG0477	Major facilitator Superfamily
D9C22_04215	COG0387	Pfam Sodium calcium exchanger
D9C22_04225	COG0668	transmembrane transport
D9C22_04230	COG0535	radical SAM domain protein
D9C22_04240	COG0726	polysaccharide deacetylase
D9C22_04245	COG2084	Dehydrogenase
D9C22_04250	COG0598	Magnesium transport protein CorA
D9C22_04255	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9C22_04260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C22_04270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C22_04275	COG4637	Psort location Cytoplasmic, score
D9C22_04280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C22_04285	COG0022	dehydrogenase e1 component
D9C22_04290	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C22_04295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C22_04300	COG3284	Transcriptional regulator
D9C22_04310	COG1742	UPF0060 membrane protein
D9C22_04335	COG4842	Belongs to the WXG100 family
D9C22_04340	COG1486	melibiose metabolic process
D9C22_04345	COG1737	Transcriptional regulator
D9C22_04350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_04350	COG1263	PTS System
D9C22_04355	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C22_04360	COG1132	(ABC) transporter
D9C22_04365	COG1132	(ABC) transporter
D9C22_04370	COG2259	Doxx family
D9C22_04375	COG2514	catechol 2,3-dioxygenase activity
D9C22_04380	COG4585	Histidine kinase
D9C22_04385	COG2197	response regulator
D9C22_04395	COG1131	(ABC) transporter
D9C22_04400	COG0842	Transport permease protein
D9C22_04400	COG1511	domain protein
D9C22_04405	COG0842	Transport permease protein
D9C22_04410	COG1695	Transcriptional regulator
D9C22_04415	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C22_04420	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D9C22_04425	COG2318	DinB family
D9C22_04430	COG2814	Major facilitator Superfamily
D9C22_04435	COG1846	Transcriptional regulator
D9C22_04440	COG0392	lysyltransferase activity
D9C22_04440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9C22_04445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C22_04450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C22_04455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C22_04460	COG0384	phenazine biosynthesis protein PhzF
D9C22_04465	COG0778	Nitroreductase
D9C22_04480	COG1090	epimerase
D9C22_04485	COG2137	regulation of response to DNA damage stimulus
D9C22_04495	COG2814	Major facilitator Superfamily
D9C22_04510	COG3103	Sh3 type 3 domain protein
D9C22_04515	COG5658	integral membrane protein
D9C22_04520	COG0596	Alpha beta hydrolase
D9C22_04525	COG0463	Glycosyl transferase, family 2
D9C22_04530	COG4485	Bacterial membrane protein, YfhO
D9C22_04535	COG1988	membrane-bound metal-dependent
D9C22_04540	COG1194	a g-specific adenine glycosylase
D9C22_04550	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_04565	COG3557	Belongs to the UPF0374 family
D9C22_04570	COG1132	(ABC) transporter
D9C22_04575	COG4129	membrane
D9C22_04580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C22_04585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9C22_04590	COG0735	belongs to the Fur family
D9C22_04700	COG4326	sporulation control protein
D9C22_04710	COG5577	PFAM Coat F domain
D9C22_04720	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D9C22_04735	COG0753	catalase activity
D9C22_04740	COG1116	anion transmembrane transporter activity
D9C22_04745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C22_04750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C22_04755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C22_04765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9C22_04775	COG1476	TRANSCRIPTIONal
D9C22_04785	COG3382	B3 4 domain protein
D9C22_04790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D9C22_04800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D9C22_04805	COG0789	Transcriptional regulator
D9C22_04810	COG1664	Polymer-forming cytoskeletal
D9C22_04815	COG1664	Polymer-forming cytoskeletal
D9C22_04820	COG2766	serine protein kinase
D9C22_04825	COG2718	Belongs to the UPF0229 family
D9C22_04830	COG1846	Transcriptional regulator
D9C22_04835	COG1566	PFAM secretion protein HlyD family protein
D9C22_04840	COG2814	Major facilitator Superfamily
D9C22_04845	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9C22_04865	COG1725	Transcriptional regulator
D9C22_04870	COG1131	(ABC) transporter
D9C22_04875	COG1131	(ABC) transporter
D9C22_04880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C22_04885	COG1278	Cold shock
D9C22_04895	COG1464	Belongs to the NlpA lipoprotein family
D9C22_04900	COG3706	GGDEF domain
D9C22_04905	COG1823	symporter activity
D9C22_04935	COG5577	PFAM Coat F domain
D9C22_04940	COG4085	toxin activity
D9C22_04940	COG0737	Belongs to the 5'-nucleotidase family
D9C22_04940	COG1525	nuclease
D9C22_04945	COG3764	Sortase (surface protein transpeptidase)
D9C22_04950	COG0564	pseudouridine synthase activity
D9C22_04960	COG0517	IMP dehydrogenase activity
D9C22_04965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C22_04970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C22_04970	COG3153	acetyltransferase
D9C22_04980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C22_04985	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9C22_04990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9C22_04995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9C22_05000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9C22_05005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C22_05010	COG4585	Histidine kinase
D9C22_05010	COG2203	Gaf domain
D9C22_05015	COG2197	response regulator
D9C22_05020	COG0431	NADPH-dependent FMN reductase
D9C22_05035	COG0791	NLP P60 protein
D9C22_05035	COG1388	LysM domain
D9C22_05040	COG1959	2 iron, 2 sulfur cluster binding
D9C22_05045	COG0668	transmembrane transport
D9C22_05050	COG2719	SpoVR family
D9C22_05055	COG1785	Belongs to the alkaline phosphatase family
D9C22_05060	COG0791	NLP P60 protein
D9C22_05060	COG1388	LysM domain
D9C22_05065	COG0583	DNA-binding transcription factor activity
D9C22_05070	COG0372	Belongs to the citrate synthase family
D9C22_05075	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_05080	COG0531	amino acid
D9C22_05085	COG0733	neurotransmitter:sodium symporter activity
D9C22_05090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C22_05095	COG0456	acetyltransferase
D9C22_05110	COG1595	DNA-templated transcription, initiation
D9C22_05115	COG0667	Aldo Keto reductase
D9C22_05120	COG0204	Acyl-transferase
D9C22_05125	COG1253	flavin adenine dinucleotide binding
D9C22_05130	COG0789	Transcriptional regulator
D9C22_05135	COG0436	Aminotransferase
D9C22_05140	COG1253	flavin adenine dinucleotide binding
D9C22_05145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C22_05150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C22_05155	COG0584	glycerophosphoryl diester phosphodiesterase
D9C22_05165	COG0668	transmembrane transport
D9C22_05170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9C22_05175	COG0726	polysaccharide deacetylase
D9C22_05180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C22_05185	COG1757	Na H antiporter
D9C22_05190	COG0589	response to stress
D9C22_05200	COG1132	(ABC) transporter
D9C22_05205	COG1132	(ABC) transporter
D9C22_05210	COG0702	epimerase
D9C22_05230	COG0189	ligase activity
D9C22_05235	COG0189	ligase activity
D9C22_05240	COG4399	Belongs to the UPF0754 family
D9C22_05245	COG3679	Belongs to the UPF0342 family
D9C22_05250	COG4335	DNA alkylation repair
D9C22_05255	COG0561	phosphatase activity
D9C22_05260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C22_05265	COG0475	glutathione-regulated potassium exporter activity
D9C22_05270	COG0490	domain, Protein
D9C22_05280	COG1024	Enoyl-CoA hydratase
D9C22_05290	COG4152	abc transporter atp-binding protein
D9C22_05295	COG1668	transmembrane transport
D9C22_05300	COG0420	3'-5' exonuclease activity
D9C22_05305	COG4717	serine-type aminopeptidase activity
D9C22_05310	COG3481	metal-dependent phosphohydrolase, HD sub domain
D9C22_05320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C22_05350	COG1846	Transcriptional regulator
D9C22_05355	COG4980	gas vesicle protein
D9C22_05370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D9C22_05375	COG0537	adenosine 5'-monophosphoramidase activity
D9C22_05380	COG1131	(ABC) transporter
D9C22_05385	COG4473	ABC transporter
D9C22_05395	COG1473	amidohydrolase
D9C22_05400	COG3069	C4-dicarboxylate transmembrane transporter activity
D9C22_05410	COG2329	Antibiotic biosynthesis monooxygenase
D9C22_05415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C22_05435	COG1309	transcriptional regulator
D9C22_05440	COG1511	domain protein
D9C22_05445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C22_05450	COG4377	Putative membrane peptidase family (DUF2324)
D9C22_05460	COG1363	Peptidase, m42
D9C22_05465	COG4405	Protein conserved in bacteria
D9C22_05470	COG1301	dicarboxylic acid transport
D9C22_05480	COG1234	tRNA 3'-trailer cleavage
D9C22_05485	COG0095	Lipoate-protein ligase
D9C22_05490	COG0702	epimerase
D9C22_05495	COG0318	PFAM AMP-dependent synthetase and ligase
D9C22_05505	COG0501	Belongs to the peptidase M48B family
D9C22_05515	COG0456	acetyltransferase
D9C22_05520	COG0604	alcohol dehydrogenase
D9C22_05525	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9C22_05530	COG0406	alpha-ribazole phosphatase activity
D9C22_05535	COG0183	Belongs to the thiolase family
D9C22_05540	COG0318	PFAM AMP-dependent synthetase and ligase
D9C22_05545	COG1268	BioY protein
D9C22_05550	COG0840	transmembrane signaling receptor activity
D9C22_05555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C22_05555	COG0723	plastoquinol--plastocyanin reductase activity
D9C22_05560	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_05570	COG4903	ComK protein
D9C22_05575	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_05585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C22_05600	COG0398	Pfam SNARE associated Golgi protein
D9C22_05605	COG0681	Belongs to the peptidase S26 family
D9C22_05610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9C22_05615	COG1846	Transcriptional regulator
D9C22_05630	COG0738	Major facilitator superfamily
D9C22_05635	COG0673	inositol 2-dehydrogenase activity
D9C22_05640	COG0561	phosphatase activity
D9C22_05645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C22_05650	COG1609	Transcriptional regulator
D9C22_05655	COG3180	Ammonia monooxygenase
D9C22_05660	COG0477	Major facilitator Superfamily
D9C22_05660	COG2814	Major facilitator Superfamily
D9C22_05665	COG4533	DNA binding
D9C22_05675	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D9C22_05680	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D9C22_05685	COG1074	ATP-dependent DNA helicase activity
D9C22_05690	COG0420	3'-5' exonuclease activity
D9C22_05695	COG0419	ATPase involved in DNA repair
D9C22_05700	COG1403	HNH endonuclease
D9C22_05740	COG5337	Spore coat protein CotH
D9C22_05745	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9C22_05755	COG1404	Belongs to the peptidase S8 family
D9C22_05765	COG0367	asparagine synthase
D9C22_05770	COG2318	DinB family
D9C22_05775	COG1562	ergosterol biosynthetic process
D9C22_05780	COG0534	Mate efflux family protein
D9C22_05785	COG1917	Cupin 2, conserved barrel domain protein
D9C22_05785	COG2207	Transcriptional regulator
D9C22_05790	COG1609	Transcriptional regulator
D9C22_05795	COG0673	inositol 2-dehydrogenase activity
D9C22_05800	COG2318	DinB family
D9C22_05805	COG1279	arginine transmembrane transporter activity
D9C22_05810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C22_05815	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C22_05820	COG2267	carboxylic ester hydrolase activity
D9C22_05825	COG0529	Catalyzes the synthesis of activated sulfate
D9C22_05830	COG2046	Belongs to the sulfate adenylyltransferase family
D9C22_05835	COG0175	sulfate reduction
D9C22_05840	COG2045	Belongs to the ComB family
D9C22_05845	COG1809	phosphosulfolactate synthase activity
D9C22_05850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C22_05855	COG4948	Mandelate Racemase Muconate Lactonizing
D9C22_05860	COG2814	Major facilitator Superfamily
D9C22_05865	COG0454	-acetyltransferase
D9C22_05870	COG2153	protein acetylation
D9C22_05875	COG0646	methionine synthase
D9C22_05875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9C22_05880	COG1666	GTP binding
D9C22_05885	COG2996	Protein conserved in bacteria
D9C22_05905	COG1695	Transcriptional regulator
D9C22_05920	COG3227	Zinc metalloprotease (Elastase)
D9C22_05925	COG1307	EDD domain protein, DegV family
D9C22_05930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C22_05945	COG0561	phosphatase activity
D9C22_05950	COG1073	alpha beta
D9C22_05955	COG2151	metal-sulfur cluster biosynthetic enzyme
D9C22_05965	COG0277	FAD linked oxidase domain protein
D9C22_05970	COG2271	Major facilitator Superfamily
D9C22_05975	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9C22_05990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C22_05995	COG0505	Belongs to the CarA family
D9C22_06000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C22_06005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9C22_06020	COG2267	carboxylic ester hydrolase activity
D9C22_06030	COG1744	ABC transporter substrate-binding protein PnrA-like
D9C22_06045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C22_06050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9C22_06055	COG5504	Zn-dependent protease
D9C22_06060	COG0444	Belongs to the ABC transporter superfamily
D9C22_06065	COG4608	Belongs to the ABC transporter superfamily
D9C22_06075	COG0601	transmembrane transport
D9C22_06080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C22_06090	COG0180	Tryptophanyl-tRNA synthetase
D9C22_06095	COG4166	transmembrane transport
D9C22_06100	COG0601	transmembrane transport
D9C22_06105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C22_06110	COG0444	Belongs to the ABC transporter superfamily
D9C22_06115	COG4608	Belongs to the ABC transporter superfamily
D9C22_06120	COG2814	Major facilitator Superfamily
D9C22_06125	COG0456	acetyltransferase
D9C22_06130	COG1393	Belongs to the ArsC family
D9C22_06135	COG0861	Integral membrane protein TerC family
D9C22_06145	COG4862	establishment of competence for transformation
D9C22_06155	COG4469	Competence protein
D9C22_06160	COG1164	Oligoendopeptidase f
D9C22_06180	COG2346	COG2346, Truncated hemoglobins
D9C22_06185	COG0741	lytic transglycosylase activity
D9C22_06190	COG4116	CYTH
D9C22_06200	COG2357	RelA SpoT domain protein
D9C22_06205	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C22_06210	COG0564	pseudouridine synthase activity
D9C22_06215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9C22_06220	COG0569	domain protein
D9C22_06220	COG0475	glutathione-regulated potassium exporter activity
D9C22_06225	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9C22_06230	COG0352	thiamine-phosphate diphosphorylase activity
D9C22_06235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C22_06240	COG2104	thiamine diphosphate biosynthetic process
D9C22_06245	COG2022	thiamine diphosphate biosynthetic process
D9C22_06250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C22_06255	COG0351	phosphomethylpyrimidine kinase
D9C22_06260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9C22_06315	COG0210	DNA helicase
D9C22_06325	COG2153	protein acetylation
D9C22_06330	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C22_06335	COG2382	esterase
D9C22_06340	COG0626	cystathionine gamma-synthase activity
D9C22_06345	COG0626	cystathionine gamma-synthase activity
D9C22_06350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C22_06355	COG5505	Protein of unknown function (DUF819)
D9C22_06375	COG5444	nuclease activity
D9C22_06420	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C22_06425	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_06435	COG3711	transcriptional antiterminator
D9C22_06435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C22_06440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C22_06440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C22_06440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C22_06445	COG1482	cell wall glycoprotein biosynthetic process
D9C22_06455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C22_06465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9C22_06485	COG0109	protoheme IX farnesyltransferase activity
D9C22_06495	COG0726	polysaccharide deacetylase
D9C22_06510	COG5504	Zn-dependent protease
D9C22_06515	COG2205	protein histidine kinase activity
D9C22_06525	COG3383	formate dehydrogenase (NAD+) activity
D9C22_06530	COG2427	Protein of unknown function (DUF1641)
D9C22_06550	COG2124	cytochrome p450
D9C22_06555	COG1819	glycosyl
D9C22_06575	COG1587	Uroporphyrinogen-III synthase
D9C22_06580	COG0390	transport system, permease component
D9C22_06585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C22_06590	COG0697	spore germination
D9C22_06595	COG4297	protein containing double-stranded beta helix domain
D9C22_06605	COG1252	NADH dehydrogenase
D9C22_06610	COG1904	glucuronate isomerase
D9C22_06615	COG2211	Major facilitator Superfamily
D9C22_06620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D9C22_06625	COG1063	alcohol dehydrogenase
D9C22_06630	COG1312	Catalyzes the dehydration of D-mannonate
D9C22_06635	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_06640	COG2271	Major facilitator Superfamily
D9C22_06645	COG1609	Transcriptional regulator
D9C22_06650	COG0246	Mannitol dehydrogenase
D9C22_06655	COG2721	sulfolactate sulfo-lyase activity
D9C22_06660	COG0730	response to heat
D9C22_06665	COG2318	DinB family
D9C22_06670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9C22_06675	COG0457	Tetratricopeptide repeat
D9C22_06685	COG2350	Protein conserved in bacteria
D9C22_06690	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C22_06690	COG3409	Peptidoglycan-binding domain 1 protein
D9C22_06690	COG1388	LysM domain
D9C22_06700	COG4195	phage-related replication protein
D9C22_06705	COG3546	catalase activity
D9C22_06710	COG2856	Zn peptidase
D9C22_06715	COG1396	sequence-specific DNA binding
D9C22_06725	COG1522	sequence-specific DNA binding
D9C22_06730	COG1484	DNA-dependent DNA replication
D9C22_06750	COG1595	DNA-templated transcription, initiation
D9C22_06755	COG3728	DNA packaging
D9C22_06755	COG5484	DNA packaging
D9C22_06760	COG1783	phage Terminase large subunit
D9C22_06765	COG5518	Phage portal protein
D9C22_06770	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9C22_06775	COG4653	Phage capsid family
D9C22_06825	COG3953	SLT domain
D9C22_06825	COG5412	phage tail tape measure protein
D9C22_06830	COG1652	LysM domain
D9C22_06835	COG4193	domain, Protein
D9C22_06845	COG3628	GPW Gp25 family protein
D9C22_06850	COG3299	homolog of phage Mu protein gp47
D9C22_06855	COG3778	Protein conserved in bacteria
D9C22_06895	COG3409	Peptidoglycan-binding domain 1 protein
D9C22_06895	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C22_06915	COG0306	phosphate transporter
D9C22_06920	COG1392	Phosphate transport regulator
D9C22_06925	COG0531	amino acid
D9C22_06930	COG0346	lactoylglutathione lyase activity
D9C22_06940	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C22_06945	COG0463	Glycosyl transferase, family 2
D9C22_06955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C22_06960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C22_06965	COG2362	D-Aminopeptidase
D9C22_06970	COG0601	transmembrane transport
D9C22_06975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C22_06980	COG0444	Belongs to the ABC transporter superfamily
D9C22_06985	COG4166	transmembrane transport
D9C22_06990	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C22_06995	COG4948	Mandelate Racemase Muconate Lactonizing
D9C22_07000	COG0791	NLP P60 protein
D9C22_07005	COG4608	Belongs to the ABC transporter superfamily
D9C22_07010	COG2706	6-phosphogluconolactonase activity
D9C22_07015	COG1834	amidinotransferase
D9C22_07020	COG1607	acyl-coa hydrolase
D9C22_07025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9C22_07025	COG1017	nitric oxide dioxygenase activity
D9C22_07035	COG2323	membrane
D9C22_07040	COG2318	DinB family
D9C22_07045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C22_07050	COG2076	Multidrug Resistance protein
D9C22_07055	COG2076	Multidrug Resistance protein
D9C22_07060	COG0788	formyltetrahydrofolate deformylase activity
D9C22_07065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9C22_07070	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9C22_07075	COG1764	response to oxidative stress
D9C22_07080	COG1846	Transcriptional regulator
D9C22_07085	COG1764	response to oxidative stress
D9C22_07095	COG0590	tRNA wobble adenosine to inosine editing
D9C22_07100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C22_07105	COG1404	Belongs to the peptidase S8 family
D9C22_07110	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C22_07115	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C22_07120	COG1122	ATPase activity
D9C22_07125	COG4721	ABC-type cobalt transport system, permease component
D9C22_07135	COG0745	RESPONSE REGULATOR receiver
D9C22_07140	COG3850	Histidine kinase
D9C22_07140	COG5002	protein histidine kinase activity
D9C22_07145	COG3212	peptidase
D9C22_07150	COG3212	peptidase
D9C22_07165	COG2239	Acts as a magnesium transporter
D9C22_07170	COG0789	Transcriptional regulator
D9C22_07185	COG1846	Transcriptional regulator
D9C22_07190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C22_07195	COG0726	polysaccharide deacetylase
D9C22_07200	COG1408	metallophosphoesterase
D9C22_07210	COG0463	Glycosyl transferase, family 2
D9C22_07215	COG3285	dna ligase
D9C22_07215	COG1793	dna ligase
D9C22_07220	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9C22_07225	COG3300	MHYT domain
D9C22_07225	COG5001	Diguanylate cyclase
D9C22_07230	COG0586	Pfam SNARE associated Golgi protein
D9C22_07235	COG0861	Integral membrane protein TerC family
D9C22_07240	COG1191	sigma factor activity
D9C22_07260	COG0501	Belongs to the peptidase M48B family
D9C22_07265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C22_07280	COG3594	Acyltransferase
D9C22_07285	COG5002	protein histidine kinase activity
D9C22_07290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9C22_07300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D9C22_07305	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D9C22_07310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C22_07315	COG0436	Aminotransferase
D9C22_07320	COG1850	ribulose-bisphosphate carboxylase activity
D9C22_07325	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D9C22_07330	COG0235	Class ii aldolase
D9C22_07335	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D9C22_07340	COG3339	Conserved Protein
D9C22_07355	COG3852	Histidine kinase
D9C22_07360	COG1846	Transcriptional regulator
D9C22_07365	COG1360	Flagellar Motor Protein
D9C22_07370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C22_07375	COG0542	response to heat
D9C22_07380	COG3949	Membrane
D9C22_07385	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D9C22_07390	COG0720	synthase
D9C22_07395	COG0602	queuosine metabolic process
D9C22_07400	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9C22_07405	COG1733	regulation of RNA biosynthetic process
D9C22_07410	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_07415	COG1388	LysM domain
D9C22_07415	COG4641	Protein conserved in bacteria
D9C22_07420	COG1388	LysM domain
D9C22_07435	COG4873	Protein conserved in bacteria
D9C22_07445	COG3773	Cell wall hydrolase
D9C22_07450	COG2244	polysaccharide biosynthetic process
D9C22_07455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C22_07460	COG2217	Heavy metal translocating P-type atpase
D9C22_07470	COG0006	proline dipeptidase activity
D9C22_07475	COG1609	Transcriptional regulator
D9C22_07480	COG3711	transcriptional antiterminator
D9C22_07485	COG2190	(PTS) system
D9C22_07485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_07485	COG1263	PTS System
D9C22_07490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C22_07495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9C22_07505	COG1533	DNA photolyase activity
D9C22_07510	COG0456	acetyltransferase
D9C22_07515	COG0840	transmembrane signaling receptor activity
D9C22_07520	COG2084	Dehydrogenase
D9C22_07525	COG4257	antibiotic catabolic process
D9C22_07530	COG2340	Cysteine-rich secretory protein family
D9C22_07535	COG0768	penicillin binding
D9C22_07540	COG4191	Histidine kinase
D9C22_07545	COG0436	Aminotransferase
D9C22_07555	COG0835	chemotaxis
D9C22_07555	COG0784	Response regulator, receiver
D9C22_07565	COG2814	Major facilitator Superfamily
D9C22_07570	COG1376	ErfK ybiS ycfS ynhG family protein
D9C22_07575	COG1408	metallophosphoesterase
D9C22_07580	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_07585	COG2200	EAL domain
D9C22_07590	COG4703	Protein of unknown function (DUF1797)
D9C22_07595	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D9C22_07605	COG0517	IMP dehydrogenase activity
D9C22_07610	COG0583	DNA-binding transcription factor activity
D9C22_07615	COG0716	FMN binding
D9C22_07625	COG0716	FMN binding
D9C22_07630	COG2171	N-acyltransferase activity
D9C22_07635	COG1473	amidohydrolase
D9C22_07645	COG0668	transmembrane transport
D9C22_07650	COG0450	alkyl hydroperoxide reductase
D9C22_07655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C22_07670	COG0746	molybdenum cofactor guanylyltransferase activity
D9C22_07675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C22_07680	COG0303	'Molybdopterin
D9C22_07685	COG1763	Mo-molybdopterin cofactor biosynthetic process
D9C22_07690	COG0314	molybdopterin synthase activity
D9C22_07695	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D9C22_07700	COG1132	(ABC) transporter
D9C22_07705	COG1132	(ABC) transporter
D9C22_07715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C22_07720	COG1136	(ABC) transporter
D9C22_07725	COG0577	efflux transmembrane transporter activity
D9C22_07730	COG1349	DNA-binding transcription factor activity
D9C22_07735	COG1105	Belongs to the carbohydrate kinase PfkB family
D9C22_07740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C22_07740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C22_07740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C22_07745	COG0681	Belongs to the peptidase S26 family
D9C22_07755	COG0488	(ABC) transporter
D9C22_07760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C22_07765	COG2309	aminopeptidase activity
D9C22_07775	COG1077	Cell shape determining protein MreB Mrl
D9C22_07780	COG2002	toxin-antitoxin pair type II binding
D9C22_07785	COG3852	Histidine kinase
D9C22_07790	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D9C22_07790	COG2105	PFAM AIG2 family protein
D9C22_07795	COG0569	domain protein
D9C22_07800	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C22_07805	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C22_07815	COG0561	phosphatase activity
D9C22_07820	COG0242	peptide deformylase activity
D9C22_07830	COG0497	DNA recombination
D9C22_07835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C22_07840	COG0022	dehydrogenase e1 component
D9C22_07845	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C22_07850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C22_07855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C22_07865	COG1982	Orn Lys Arg decarboxylase major
D9C22_07870	COG4476	Belongs to the UPF0223 family
D9C22_07875	COG4493	Belongs to the UPF0637 family
D9C22_07885	COG0483	inositol monophosphate 1-phosphatase activity
D9C22_07895	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9C22_07945	COG4896	Protein conserved in bacteria
D9C22_07955	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D9C22_07960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C22_07965	COG2066	Belongs to the glutaminase family
D9C22_07970	COG4838	Belongs to the UPF0358 family
D9C22_07975	COG0772	Belongs to the SEDS family
D9C22_07980	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9C22_07985	COG1612	heme a metabolic process
D9C22_07990	COG0109	protoheme IX farnesyltransferase activity
D9C22_08000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C22_08005	COG1845	cytochrome c oxidase, subunit III
D9C22_08010	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C22_08015	COG3336	cytochrome c oxidase
D9C22_08025	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D9C22_08030	COG2340	Cysteine-rich secretory protein family
D9C22_08045	COG3679	Belongs to the UPF0342 family
D9C22_08050	COG4471	UPF0298 protein
D9C22_08055	COG0742	ribosomal rna small subunit methyltransferase
D9C22_08060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9C22_08065	COG3314	Sporulation integral membrane protein YlbJ
D9C22_08070	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C22_08075	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9C22_08080	COG1323	Belongs to the UPF0348 family
D9C22_08090	COG1399	metal-binding, possibly nucleic acid-binding protein
D9C22_08095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D9C22_08105	COG0454	-acetyltransferase
D9C22_08110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C22_08115	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D9C22_08120	COG2001	Belongs to the MraZ family
D9C22_08125	COG0275	rRNA processing
D9C22_08130	COG4839	cell division protein FtsL
D9C22_08140	COG0768	penicillin binding
D9C22_08145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9C22_08150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C22_08155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C22_08160	COG0772	Belongs to the SEDS family
D9C22_08165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C22_08170	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9C22_08175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D9C22_08180	COG3879	Bacterial protein of unknown function (DUF881)
D9C22_08185	COG3879	Bacterial protein of unknown function (DUF881)
D9C22_08190	COG3856	small basic protein
D9C22_08195	COG0849	cell division
D9C22_08200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9C22_08205	COG1404	Belongs to the peptidase S8 family
D9C22_08205	COG4412	M6 family metalloprotease domain protein
D9C22_08215	COG1191	sigma factor activity
D9C22_08220	COG1191	sigma factor activity
D9C22_08225	COG1119	ATPase activity
D9C22_08230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C22_08235	COG1873	PFAM PRC-barrel domain
D9C22_08245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9C22_08250	COG1799	cell septum assembly
D9C22_08255	COG0762	integral membrane protein
D9C22_08260	COG2302	S4 RNA-binding domain
D9C22_08265	COG3599	regulation of cell shape
D9C22_08275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C22_08280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9C22_08285	COG0564	pseudouridine synthase activity
D9C22_08290	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9C22_08295	COG2233	PERMEase
D9C22_08300	COG0540	Belongs to the ATCase OTCase family
D9C22_08305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C22_08310	COG0505	Belongs to the CarA family
D9C22_08315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C22_08320	COG0543	2 iron, 2 sulfur cluster binding
D9C22_08325	COG0167	dihydroorotate dehydrogenase activity
D9C22_08330	COG0284	orotidine-5'-phosphate decarboxylase activity
D9C22_08335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D9C22_08340	COG0175	sulfate reduction
D9C22_08345	COG0306	phosphate transporter
D9C22_08350	COG2046	Belongs to the sulfate adenylyltransferase family
D9C22_08355	COG0529	Catalyzes the synthesis of activated sulfate
D9C22_08360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C22_08365	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D9C22_08370	COG1648	precorrin-2 dehydrogenase activity
D9C22_08380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C22_08385	COG1561	YicC-like family, N-terminal region
D9C22_08390	COG2052	Domain of unknown function (DUF370)
D9C22_08395	COG0194	GDP metabolic process
D9C22_08400	COG1758	RNA polymerase activity
D9C22_08405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C22_08410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C22_08415	COG0242	peptide deformylase activity
D9C22_08420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9C22_08425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9C22_08425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C22_08430	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9C22_08435	COG0631	protein serine/threonine phosphatase activity
D9C22_08440	COG2815	serine threonine protein kinase
D9C22_08440	COG0515	serine threonine protein kinase
D9C22_08445	COG1162	GTPase activity
D9C22_08450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9C22_08455	COG1564	THIamine pyrophosphokinase
D9C22_08465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9C22_08470	COG1302	Protein conserved in bacteria
D9C22_08475	COG1461	Dihydroxyacetone kinase
D9C22_08480	COG1760	l-serine dehydratase
D9C22_08485	COG1760	l-serine dehydratase
D9C22_08490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9C22_08495	COG2050	protein possibly involved in aromatic compounds catabolism
D9C22_08495	COG1349	DNA-binding transcription factor activity
D9C22_08500	COG0416	fatty acid biosynthetic process
D9C22_08505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9C22_08510	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_08515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C22_08520	COG0571	ribonuclease III activity
D9C22_08525	COG1196	nuclear chromosome segregation
D9C22_08530	COG0552	protein localization to endoplasmic reticulum
D9C22_08540	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D9C22_08545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9C22_08550	COG0228	four-way junction DNA binding
D9C22_08555	COG1837	Belongs to the UPF0109 family
D9C22_08565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9C22_08570	COG0336	Belongs to the RNA methyltransferase TrmD family
D9C22_08575	COG0335	large ribosomal subunit rRNA binding
D9C22_08580	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C22_08585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C22_08595	COG2257	FlhB HrpN YscU SpaS Family
D9C22_08600	COG0045	succinate-CoA ligase (ADP-forming) activity
D9C22_08605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9C22_08610	COG0758	DNA mediated transformation
D9C22_08615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C22_08620	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D9C22_08625	COG4974	Belongs to the 'phage' integrase family
D9C22_08630	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D9C22_08635	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9C22_08640	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C22_08645	COG1815	bacterial-type flagellum-dependent cell motility
D9C22_08650	COG1558	bacterial-type flagellum-dependent cell motility
D9C22_08655	COG1677	Flagellar hook-basal body complex protein FliE
D9C22_08660	COG1766	The M ring may be actively involved in energy transduction
D9C22_08665	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C22_08670	COG1317	bacterial-type flagellum organization
D9C22_08675	COG1157	protein secretion by the type III secretion system
D9C22_08680	COG2882	bacterial-type flagellum organization
D9C22_08685	COG3334	PFAM MgtE intracellular
D9C22_08690	COG3144	bacterial-type flagellum assembly
D9C22_08695	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9C22_08700	COG4786	Flagellar basal body rod
D9C22_08705	COG1582	Flagellar protein (FlbD)
D9C22_08710	COG1580	Controls the rotational direction of flagella during chemotaxis
D9C22_08715	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C22_08720	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C22_08720	COG1776	CheC inhibitor of MCP methylation
D9C22_08725	COG2201	protein-glutamate methylesterase activity
D9C22_08730	COG3190	flagellar
D9C22_08735	COG1338	Plays a role in the flagellum-specific transport system
D9C22_08740	COG1987	bacterial-type flagellum assembly
D9C22_08745	COG1684	flagellar biosynthetic protein fliR
D9C22_08750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C22_08755	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C22_08760	COG1419	protein localization to endoplasmic reticulum
D9C22_08765	COG0455	bacterial-type flagellum organization
D9C22_08770	COG2201	protein-glutamate methylesterase activity
D9C22_08775	COG2198	Histidine kinase
D9C22_08775	COG0643	Histidine kinase
D9C22_08780	COG0835	chemotaxis
D9C22_08785	COG1776	CheC inhibitor of MCP methylation
D9C22_08790	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D9C22_08795	COG1191	sigma factor activity
D9C22_08805	COG0052	Belongs to the universal ribosomal protein uS2 family
D9C22_08810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D9C22_08815	COG0528	UMP kinase activity
D9C22_08820	COG0233	cytoplasmic translational termination
D9C22_08825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9C22_08830	COG4589	Belongs to the CDS family
D9C22_08835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9C22_08840	COG0750	zinc metalloprotease
D9C22_08845	COG0442	prolyl-tRNA aminoacylation
D9C22_08850	COG2176	DNA-directed DNA polymerase activity
D9C22_08880	COG0779	Required for maturation of 30S ribosomal subunits
D9C22_08885	COG0195	Participates in both transcription termination and antitermination
D9C22_08890	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9C22_08895	COG1358	cellular component organization or biogenesis
D9C22_08900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D9C22_08905	COG1550	Protein conserved in bacteria
D9C22_08910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D9C22_08915	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9C22_08920	COG0196	riboflavin kinase activity
D9C22_08925	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D9C22_08930	COG1185	polyribonucleotide nucleotidyltransferase activity
D9C22_08935	COG0726	polysaccharide deacetylase
D9C22_08940	COG0612	Peptidase, M16
D9C22_08945	COG1873	PFAM PRC-barrel domain
D9C22_08950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C22_08955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C22_08960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9C22_08965	COG0527	aspartate kinase activity
D9C22_08970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C22_08975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C22_08980	COG0740	serine-type endopeptidase activity
D9C22_08990	COG4980	gas vesicle protein
D9C22_08990	COG1674	ftsk spoiiie
D9C22_08995	COG2188	Transcriptional regulator
D9C22_09000	COG2814	Major facilitator Superfamily
D9C22_09005	COG0612	Peptidase, M16
D9C22_09010	COG0612	Peptidase, M16
D9C22_09015	COG0300	oxidoreductase activity
D9C22_09030	COG1426	Protein conserved in bacteria
D9C22_09035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9C22_09040	COG1058	Belongs to the CinA family
D9C22_09040	COG1546	Belongs to the CinA family
D9C22_09045	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D9C22_09050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C22_09055	COG1418	mRNA catabolic process
D9C22_09060	COG1692	metallophosphoesterase
D9C22_09065	COG2359	stage V sporulation protein S
D9C22_09070	COG1063	alcohol dehydrogenase
D9C22_09075	COG0156	8-amino-7-oxononanoate synthase activity
D9C22_09080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C22_09085	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9C22_09095	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D9C22_09100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D9C22_09115	COG3226	Transcriptional regulator
D9C22_09120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C22_09130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9C22_09135	COG3321	synthase
D9C22_09140	COG2070	2-Nitropropane dioxygenase
D9C22_09140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9C22_09145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C22_09150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9C22_09155	COG3425	synthase
D9C22_09160	COG1024	Enoyl-CoA hydratase
D9C22_09165	COG1024	Enoyl-CoA hydratase
D9C22_09170	COG0300	oxidoreductase activity
D9C22_09170	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_09170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_09170	COG0318	PFAM AMP-dependent synthetase and ligase
D9C22_09170	COG3321	synthase
D9C22_09175	COG4221	oxidoreductase activity
D9C22_09175	COG3321	synthase
D9C22_09175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C22_09175	COG0300	oxidoreductase activity
D9C22_09180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C22_09180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C22_09180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_09180	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_09180	COG3321	synthase
D9C22_09185	COG4221	oxidoreductase activity
D9C22_09185	COG3321	synthase
D9C22_09185	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_09190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C22_09190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D9C22_09190	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D9C22_09190	COG3321	synthase
D9C22_09195	COG2124	cytochrome p450
D9C22_09205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C22_09210	COG1404	Belongs to the peptidase S8 family
D9C22_09220	COG4195	phage-related replication protein
D9C22_09225	COG1764	response to oxidative stress
D9C22_09230	COG2076	Multidrug Resistance protein
D9C22_09235	COG2076	Multidrug Resistance protein
D9C22_09250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9C22_09255	COG1923	regulation of RNA biosynthetic process
D9C22_09270	COG1780	Probably involved in ribonucleotide reductase function
D9C22_09275	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C22_09280	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C22_09285	COG4112	unkown
D9C22_09290	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C22_09300	COG0464	growth
D9C22_09305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9C22_09310	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9C22_09315	COG0789	Transcriptional regulator
D9C22_09320	COG0174	glutamine synthetase
D9C22_09345	COG4282	regulation of fungal-type cell wall biogenesis
D9C22_09355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C22_09385	COG0135	phosphoribosylanthranilate isomerase activity
D9C22_09390	COG2211	Major facilitator Superfamily
D9C22_09395	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C22_09400	COG1940	carbohydrate kinase activity
D9C22_09405	COG2115	Belongs to the xylose isomerase family
D9C22_09410	COG1070	Carbohydrate kinase
D9C22_09425	COG2814	Major facilitator Superfamily
D9C22_09430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C22_09445	COG0756	dUTP diphosphatase activity
D9C22_09485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C22_09500	COG3832	glyoxalase III activity
D9C22_09510	COG0697	spore germination
D9C22_09515	COG0531	amino acid
D9C22_09545	COG4195	phage-related replication protein
D9C22_09555	COG0346	lactoylglutathione lyase activity
D9C22_09565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9C22_09570	COG1388	LysM domain
D9C22_09575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C22_09580	COG4224	UPF0291 protein
D9C22_09585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9C22_09595	COG3763	UPF0154 protein
D9C22_09605	COG0785	Cytochrome C biogenesis protein
D9C22_09610	COG2201	protein-glutamate methylesterase activity
D9C22_09615	COG4846	Membrane protein involved in cytochrome C biogenesis
D9C22_09625	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C22_09640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9C22_09645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C22_09665	COG0824	Thioesterase
D9C22_09675	COG4841	protein insertion into membrane
D9C22_09680	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9C22_09685	COG1832	CoA-binding protein
D9C22_09690	COG0187	DNA topoisomerase II activity
D9C22_09695	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C22_09705	COG1115	amino acid carrier protein
D9C22_09710	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D9C22_09720	COG5520	Belongs to the glycosyl hydrolase 30 family
D9C22_09725	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C22_09730	COG2246	polysaccharide biosynthetic process
D9C22_09735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C22_09740	COG0586	Pfam SNARE associated Golgi protein
D9C22_09745	COG2404	hydrolase activity, acting on ester bonds
D9C22_09750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9C22_09755	COG1024	Enoyl-CoA hydratase
D9C22_09760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C22_09765	COG0511	ligase activity, forming carbon-carbon bonds
D9C22_09770	COG0439	Biotin carboxylase
D9C22_09775	COG0318	PFAM AMP-dependent synthetase and ligase
D9C22_09780	COG1960	acyl-CoA dehydrogenase activity
D9C22_09790	COG1649	PFAM Uncharacterised BCR, COG1649
D9C22_09800	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D9C22_09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_09810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_09815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_09820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_09825	COG2027	D-alanyl-D-alanine carboxypeptidase
D9C22_09830	COG2017	converts alpha-aldose to the beta-anomer
D9C22_09835	COG0534	Mate efflux family protein
D9C22_09850	COG0582	viral genome integration into host DNA
D9C22_09855	COG0166	Belongs to the GPI family
D9C22_09860	COG0405	Gamma-glutamyltransferase
D9C22_09865	COG0583	DNA-binding transcription factor activity
D9C22_09875	COG0493	'glutamate synthase
D9C22_09880	COG0070	glutamate synthase
D9C22_09880	COG0067	glutamate synthase
D9C22_09880	COG0069	glutamate synthase activity
D9C22_09885	COG0583	DNA-binding transcription factor activity
D9C22_09890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9C22_09895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C22_09905	COG0300	oxidoreductase activity
D9C22_09910	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C22_09920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C22_09935	COG1131	(ABC) transporter
D9C22_09945	COG2814	Major facilitator Superfamily
D9C22_09950	COG1070	Carbohydrate kinase
D9C22_09955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9C22_09960	COG0243	molybdopterin cofactor binding
D9C22_09970	COG2814	Major facilitator Superfamily
D9C22_09975	COG0673	inositol 2-dehydrogenase activity
D9C22_09980	COG1082	Xylose isomerase domain protein TIM barrel
D9C22_09985	COG1609	Transcriptional regulator
D9C22_10005	COG0840	transmembrane signaling receptor activity
D9C22_10005	COG5278	phosphoserine phosphatase activity
D9C22_10010	COG2368	4-hydroxyphenylacetate
D9C22_10015	COG4305	rare lipoprotein A
D9C22_10020	COG3619	membrane
D9C22_10025	COG3866	Pectate lyase
D9C22_10030	COG2135	peptidase activity
D9C22_10040	COG2140	Oxalate decarboxylase
D9C22_10060	COG2720	vancomycin resistance protein
D9C22_10075	COG3739	integral membrane protein
D9C22_10080	COG0583	DNA-binding transcription factor activity
D9C22_10085	COG0697	spore germination
D9C22_10095	COG0693	protein deglycase activity
D9C22_10100	COG2367	Beta-lactamase
D9C22_10120	COG0574	Belongs to the PEP-utilizing enzyme family
D9C22_10120	COG3848	Pyruvate phosphate dikinase
D9C22_10125	COG0726	polysaccharide deacetylase
D9C22_10135	COG2314	TM2 domain
D9C22_10165	COG3655	Transcriptional regulator
D9C22_10200	COG0457	Tetratricopeptide repeat
D9C22_10210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C22_10220	COG4282	regulation of fungal-type cell wall biogenesis
D9C22_10230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C22_10235	COG2207	Transcriptional regulator
D9C22_10235	COG0662	Cupin 2, conserved barrel domain protein
D9C22_10240	COG0456	acetyltransferase
D9C22_10245	COG1309	transcriptional regulator
D9C22_10250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C22_10255	COG3708	Transcriptional regulator
D9C22_10260	COG2378	regulation of single-species biofilm formation
D9C22_10270	COG0640	Transcriptional regulator
D9C22_10275	COG0741	lytic transglycosylase activity
D9C22_10280	COG2322	membrane
D9C22_10295	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C22_10300	COG3239	Fatty acid desaturase
D9C22_10305	COG4585	Histidine kinase
D9C22_10310	COG2197	response regulator
D9C22_10315	COG1388	LysM domain
D9C22_10315	COG3584	3D domain protein
D9C22_10335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9C22_10340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C22_10355	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C22_10380	COG1012	belongs to the aldehyde dehydrogenase family
D9C22_10385	COG1657	PFAM Prenyltransferase squalene oxidase
D9C22_10390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C22_10395	COG0733	neurotransmitter:sodium symporter activity
D9C22_10400	COG0385	Bile acid
D9C22_10405	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C22_10410	COG0567	Dehydrogenase, E1 component
D9C22_10415	COG4548	von Willebrand factor, type A
D9C22_10420	COG0714	Associated with various cellular activities
D9C22_10425	COG2032	superoxide dismutase activity
D9C22_10430	COG1388	LysM domain
D9C22_10430	COG0791	NLP P60 protein
D9C22_10435	COG1819	glycosyl
D9C22_10440	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C22_10445	COG0534	Mate efflux family protein
D9C22_10450	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C22_10455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C22_10460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C22_10470	COG2962	Rard protein
D9C22_10485	COG2610	gluconate transmembrane transporter activity
D9C22_10490	COG1942	4-Oxalocrotonate Tautomerase
D9C22_10495	COG1733	regulation of RNA biosynthetic process
D9C22_10500	COG0778	Nitroreductase
D9C22_10505	COG0400	carboxylic ester hydrolase activity
D9C22_10510	COG0346	lactoylglutathione lyase activity
D9C22_10520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C22_10525	COG3409	Peptidoglycan-binding domain 1 protein
D9C22_10525	COG0793	Belongs to the peptidase S41A family
D9C22_10530	COG2226	methyltransferase
D9C22_10540	COG1876	peptidase activity
D9C22_10545	COG0813	purine-nucleoside phosphorylase activity
D9C22_10560	COG0671	phosphoesterase, PA-phosphatase related
D9C22_10580	COG4479	Belongs to the UPF0346 family
D9C22_10590	COG1509	lysine 2,3-aminomutase activity
D9C22_10595	COG0456	acetyltransferase
D9C22_10600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C22_10605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9C22_10610	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C22_10615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C22_10630	COG0456	acetyltransferase
D9C22_10635	COG0463	Glycosyl transferase, family 2
D9C22_10650	COG4641	Protein conserved in bacteria
D9C22_10655	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D9C22_10660	COG1086	Polysaccharide biosynthesis protein
D9C22_10665	COG3331	DNA recombination
D9C22_10720	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C22_10725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D9C22_10755	COG0756	dUTP diphosphatase activity
D9C22_10770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C22_10800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C22_10800	COG1372	Participates in initiation and elongation during chromosome replication
D9C22_10805	COG1780	Probably involved in ribonucleotide reductase function
D9C22_10915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9C22_10940	COG3584	3D domain protein
D9C22_10945	COG0587	DNA-directed DNA polymerase activity
D9C22_10950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9C22_10955	COG0358	DNA primase activity
D9C22_10960	COG0305	Participates in initiation and elongation during chromosome replication
D9C22_10970	COG2887	Belongs to the helicase family. UvrD subfamily
D9C22_10995	COG3420	alginic acid biosynthetic process
D9C22_10995	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C22_11000	COG4195	phage-related replication protein
D9C22_11020	COG2135	peptidase activity
D9C22_11025	COG1793	dna ligase
D9C22_11060	COG4474	Belongs to the UPF0398 family
D9C22_11085	COG3646	Phage regulatory protein
D9C22_11085	COG3645	SOS response
D9C22_11130	COG3655	Transcriptional regulator
D9C22_11145	COG0582	viral genome integration into host DNA
D9C22_11215	COG3655	Transcriptional regulator
D9C22_11275	COG1395	domain, Protein
D9C22_11300	COG0776	regulation of translation
D9C22_11345	COG4373	Mu-like prophage FluMu protein gp28
D9C22_11445	COG0582	viral genome integration into host DNA
D9C22_11475	COG0741	lytic transglycosylase activity
D9C22_11475	COG0739	heme binding
D9C22_11475	COG1196	nuclear chromosome segregation
D9C22_11485	COG2433	Pfam Transposase IS66
D9C22_11495	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C22_11495	COG4632	Exopolysaccharide biosynthesis protein
D9C22_11520	COG0457	Tetratricopeptide repeat
D9C22_11530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C22_11560	COG4282	regulation of fungal-type cell wall biogenesis
D9C22_11570	COG1525	nuclease
D9C22_11585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C22_11590	COG1086	Polysaccharide biosynthesis protein
D9C22_11595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C22_11600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C22_11605	COG1846	Transcriptional regulator
D9C22_11610	COG0534	Mate efflux family protein
D9C22_11620	COG4698	Protein conserved in bacteria
D9C22_11625	COG2755	lipolytic protein G-D-S-L family
D9C22_11630	COG1999	signal sequence binding
D9C22_11640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9C22_11645	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C22_11650	COG1272	protein, Hemolysin III
D9C22_11655	COG0204	Acyl-transferase
D9C22_11660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C22_11665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C22_11675	COG2136	Putative SAM-dependent methyltransferase
D9C22_11675	COG2521	methyltransferase
D9C22_11685	COG0129	dihydroxy-acid dehydratase activity
D9C22_11690	COG1413	lyase activity
D9C22_11695	COG1418	mRNA catabolic process
D9C22_11700	COG0386	Belongs to the glutathione peroxidase family
D9C22_11705	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D9C22_11720	COG1278	Cold shock
D9C22_11740	COG0328	RNA-DNA hybrid ribonuclease activity
D9C22_11745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9C22_11750	COG0328	RNA-DNA hybrid ribonuclease activity
D9C22_11760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C22_11775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C22_11785	COG1755	Isoprenylcysteine carboxyl methyltransferase
D9C22_11790	COG3424	synthase
D9C22_11795	COG2233	PERMEase
D9C22_11800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C22_11805	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9C22_11815	COG0800	Aldolase
D9C22_11820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C22_11825	COG1609	Transcriptional regulator
D9C22_11830	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D9C22_11835	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_11840	COG1199	ATP-dependent helicase activity
D9C22_11855	COG0116	Belongs to the methyltransferase superfamily
D9C22_11870	COG4474	Belongs to the UPF0398 family
D9C22_11885	COG3359	exonuclease
D9C22_11890	COG1205	dead DEAH box helicase
D9C22_11890	COG1111	helicase
D9C22_11895	COG2190	(PTS) system
D9C22_11900	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C22_11935	COG3331	DNA recombination
D9C22_11940	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C22_11940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C22_11950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9C22_11955	COG3935	DnaD domain protein
D9C22_11960	COG0017	Asparaginyl-tRNA synthetase
D9C22_11965	COG0436	Aminotransferase
D9C22_11970	COG5353	protein conserved in bacteria
D9C22_11980	COG1199	ATP-dependent helicase activity
D9C22_11980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9C22_11985	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9C22_11990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9C22_11995	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D9C22_12000	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D9C22_12000	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D9C22_12005	COG0617	tRNA 3'-terminal CCA addition
D9C22_12010	COG0438	transferase activity, transferring glycosyl groups
D9C22_12015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C22_12020	COG1803	Methylglyoxal synthase
D9C22_12025	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9C22_12030	COG1694	Mazg nucleotide pyrophosphohydrolase
D9C22_12035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C22_12045	COG4347	Protein of unknown function (DUF1405)
D9C22_12050	COG2010	Cytochrome c
D9C22_12050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C22_12055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C22_12060	COG0723	plastoquinol--plastocyanin reductase activity
D9C22_12070	COG5582	Belongs to the UPF0302 family
D9C22_12075	COG0457	Tetratricopeptide repeat
D9C22_12080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9C22_12085	COG0287	Prephenate dehydrogenase
D9C22_12090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9C22_12100	COG0133	tryptophan synthase activity
D9C22_12105	COG0135	phosphoribosylanthranilate isomerase activity
D9C22_12115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9C22_12120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C22_12125	COG4401	Chorismate mutase type I
D9C22_12130	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9C22_12135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9C22_12140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9C22_12145	COG0105	UTP biosynthetic process
D9C22_12150	COG0142	geranyltranstransferase activity
D9C22_12155	COG2226	methyltransferase
D9C22_12160	COG0142	geranyltranstransferase activity
D9C22_12170	COG0302	gtp cyclohydrolase
D9C22_12175	COG0776	regulation of translation
D9C22_12180	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C22_12195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9C22_12200	COG1160	GTP binding
D9C22_12225	COG1304	FMN binding
D9C22_12230	COG0539	negative regulation of cytoplasmic translation
D9C22_12235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9C22_12245	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D9C22_12250	COG2959	enzyme of heme biosynthesis
D9C22_12255	COG3409	Peptidoglycan-binding domain 1 protein
D9C22_12255	COG3773	Cell wall hydrolase
D9C22_12260	COG2339	peptidase activity
D9C22_12265	COG0492	ferredoxin-NADP+ reductase activity
D9C22_12270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C22_12275	COG4862	establishment of competence for transformation
D9C22_12280	COG1408	metallophosphoesterase
D9C22_12290	COG1388	LysM domain
D9C22_12295	COG1266	CAAX protease self-immunity
D9C22_12300	COG0514	ATP-dependent DNA helicase (RecQ)
D9C22_12305	COG4955	Helix-turn-helix domain
D9C22_12310	COG1141	Ferredoxin
D9C22_12315	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9C22_12320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9C22_12325	COG0710	3-dehydroquinate dehydratase activity
D9C22_12335	COG1595	DNA-templated transcription, initiation
D9C22_12340	COG5002	protein histidine kinase activity
D9C22_12345	COG0745	RESPONSE REGULATOR receiver
D9C22_12350	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C22_12355	COG1333	cytochrome c biogenesis protein
D9C22_12360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C22_12365	COG1187	pseudouridine synthase activity
D9C22_12370	COG0700	Nucleoside recognition
D9C22_12375	COG2715	membrane protein required for spore maturation
D9C22_12380	COG1686	Belongs to the peptidase S11 family
D9C22_12390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9C22_12395	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D9C22_12400	COG1547	Domain of unknown function (DUF309)
D9C22_12405	COG0456	acetyltransferase
D9C22_12410	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9C22_12415	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C22_12415	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C22_12420	COG0307	riboflavin synthase, alpha
D9C22_12425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C22_12425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C22_12435	COG0681	Belongs to the peptidase S26 family
D9C22_12450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9C22_12460	COG4086	secreted protein
D9C22_12465	COG0019	diaminopimelate decarboxylase activity
D9C22_12470	COG0697	spore germination
D9C22_12485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C22_12505	COG1191	sigma factor activity
D9C22_12510	COG2172	sigma factor antagonist activity
D9C22_12515	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C22_12520	COG1686	Belongs to the peptidase S11 family
D9C22_12525	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D9C22_12530	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9C22_12535	COG4974	Belongs to the 'phage' integrase family
D9C22_12545	COG0735	belongs to the Fur family
D9C22_12550	COG1300	Membrane
D9C22_12560	COG0281	malic enzyme
D9C22_12565	COG1757	Na H antiporter
D9C22_12570	COG1027	Aspartate ammonia-lyase
D9C22_12575	COG0252	asparaginase activity
D9C22_12580	COG1396	sequence-specific DNA binding
D9C22_12585	COG1379	DNA repair
D9C22_12590	COG0494	nUDIX hydrolase
D9C22_12600	COG0667	Aldo Keto reductase
D9C22_12610	COG1073	alpha beta
D9C22_12620	COG4918	Iron-sulphur cluster biosynthesis
D9C22_12625	COG0456	acetyltransferase
D9C22_12625	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9C22_12630	COG2329	Antibiotic biosynthesis monooxygenase
D9C22_12635	COG0456	acetyltransferase
D9C22_12645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C22_12655	COG2211	Major facilitator Superfamily
D9C22_12660	COG0346	lactoylglutathione lyase activity
D9C22_12665	COG1072	(Pantothenic acid kinase))
D9C22_12670	COG3048	D-serine ammonia-lyase activity
D9C22_12675	COG0300	oxidoreductase activity
D9C22_12680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C22_12685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C22_12690	COG4187	Peptidase family M20/M25/M40
D9C22_12695	COG1902	pentaerythritol trinitrate reductase activity
D9C22_12700	COG0596	Alpha beta hydrolase
D9C22_12710	COG1234	tRNA 3'-trailer cleavage
D9C22_12715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9C22_12720	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C22_12725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C22_12735	COG0706	membrane insertase activity
D9C22_12740	COG3361	conserved protein (COG2071)
D9C22_12745	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C22_12750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9C22_12755	COG0346	lactoylglutathione lyase activity
D9C22_12760	COG1376	ErfK ybiS ycfS ynhG family protein
D9C22_12765	COG4129	membrane
D9C22_12770	COG1126	abc transporter atp-binding protein
D9C22_12775	COG0765	amino acid transport
D9C22_12780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C22_12790	COG1597	lipid kinase activity
D9C22_12795	COG2814	Major facilitator Superfamily
D9C22_12800	COG4978	Transcriptional regulator
D9C22_12800	COG0789	Transcriptional regulator
D9C22_12805	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C22_12810	COG0022	dehydrogenase e1 component
D9C22_12815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C22_12820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C22_12825	COG3426	butyrate kinase activity
D9C22_12830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C22_12835	COG0280	phosphate acetyltransferase
D9C22_12840	COG3829	transcription factor binding
D9C22_12840	COG3290	protein histidine kinase activity
D9C22_12850	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D9C22_12855	COG2079	MmgE PrpD family protein
D9C22_12860	COG0372	Belongs to the citrate synthase family
D9C22_12865	COG1960	acyl-CoA dehydrogenase activity
D9C22_12870	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C22_12875	COG0183	Belongs to the thiolase family
D9C22_12880	COG0584	glycerophosphoryl diester phosphodiesterase
D9C22_12885	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C22_12900	COG1902	pentaerythritol trinitrate reductase activity
D9C22_12905	COG0745	RESPONSE REGULATOR receiver
D9C22_12910	COG0750	zinc metalloprotease
D9C22_12915	COG0497	DNA recombination
D9C22_12920	COG1438	arginine binding
D9C22_12925	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9C22_12930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9C22_12935	COG0142	geranyltranstransferase activity
D9C22_12940	COG1722	exodeoxyribonuclease VII activity
D9C22_12945	COG1570	exodeoxyribonuclease VII activity
D9C22_12950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9C22_12955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C22_12960	COG1302	Protein conserved in bacteria
D9C22_12965	COG0439	Biotin carboxylase
D9C22_12970	COG0511	ligase activity, forming carbon-carbon bonds
D9C22_13010	COG3854	ATPases associated with a variety of cellular activities
D9C22_13020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9C22_13025	COG0006	proline dipeptidase activity
D9C22_13030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D9C22_13040	COG3872	metal-dependent enzyme
D9C22_13050	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C22_13055	COG1321	iron dependent repressor
D9C22_13060	COG0095	Lipoate-protein ligase
D9C22_13065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C22_13070	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C22_13075	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C22_13080	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D9C22_13085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C22_13100	COG1396	sequence-specific DNA binding
D9C22_13110	COG0681	Belongs to the peptidase S26 family
D9C22_13135	COG4940	Competence protein ComGF
D9C22_13145	COG4970	Tfp pilus assembly protein FimT
D9C22_13150	COG4537	Required for transformation and DNA binding
D9C22_13155	COG1459	type II secretion system
D9C22_13160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9C22_13170	COG0598	Magnesium transport protein CorA
D9C22_13175	COG1253	flavin adenine dinucleotide binding
D9C22_13180	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C22_13190	COG1393	Belongs to the ArsC family
D9C22_13200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C22_13210	COG0011	TIGRFAM Protein of
D9C22_13220	COG2866	Carboxypeptidase
D9C22_13225	COG1368	sulfuric ester hydrolase activity
D9C22_13230	COG1940	carbohydrate kinase activity
D9C22_13235	COG4483	Protein conserved in bacteria
D9C22_13240	COG0457	Tetratricopeptide repeat
D9C22_13240	COG0705	Rhomboid family
D9C22_13250	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9C22_13255	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9C22_13260	COG0438	transferase activity, transferring glycosyl groups
D9C22_13275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C22_13280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C22_13285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C22_13290	COG0581	inorganic phosphate transmembrane transporter activity
D9C22_13295	COG0573	inorganic phosphate transmembrane transporter activity
D9C22_13300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9C22_13310	COG0477	Major facilitator Superfamily
D9C22_13315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C22_13320	COG2839	Protein conserved in bacteria
D9C22_13325	COG5521	maltodextrose utilization protein MalA
D9C22_13330	COG1388	LysM domain
D9C22_13335	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9C22_13340	COG4709	membrane
D9C22_13345	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D9C22_13350	COG0735	belongs to the Fur family
D9C22_13355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C22_13365	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9C22_13370	COG0513	Belongs to the DEAD box helicase family
D9C22_13380	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9C22_13385	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9C22_13390	COG2384	SAM-dependent methyltransferase
D9C22_13395	COG2010	Cytochrome c
D9C22_13405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9C22_13410	COG0358	DNA primase activity
D9C22_13415	COG1671	Belongs to the UPF0178 family
D9C22_13420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9C22_13425	COG0517	IMP dehydrogenase activity
D9C22_13430	COG0751	glycine-tRNA ligase activity
D9C22_13435	COG0752	glycyl-tRNA synthetase alpha subunit
D9C22_13440	COG1381	Involved in DNA repair and RecF pathway recombination
D9C22_13450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9C22_13455	COG0295	cytidine deaminase activity
D9C22_13460	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9C22_13465	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9C22_13470	COG1480	7TM receptor with intracellular HD hydrolase
D9C22_13475	COG1702	phosphate starvation-inducible protein PhoH
D9C22_13480	COG0561	phosphatase activity
D9C22_13495	COG4864	UPF0365 protein
D9C22_13500	COG1030	water channel activity
D9C22_13505	COG1610	YqeY-like protein
D9C22_13510	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D9C22_13515	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9C22_13520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C22_13525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9C22_13530	COG2264	protein methyltransferase activity
D9C22_13535	COG0484	heat shock protein binding
D9C22_13540	COG0443	Heat shock 70 kDa protein
D9C22_13545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9C22_13550	COG1420	regulation of RNA biosynthetic process
D9C22_13555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C22_13560	COG0481	GTPase activity
D9C22_13570	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C22_13575	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D9C22_13580	COG0268	Binds directly to 16S ribosomal RNA
D9C22_13585	COG1466	dna polymerase III delta subunit
D9C22_13600	COG0658	competence protein
D9C22_13600	COG2333	competence protein COMEC
D9C22_13605	COG2131	deaminase
D9C22_13610	COG1596	polysaccharide export
D9C22_13610	COG1555	photosystem II stabilization
D9C22_13615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C22_13620	COG2226	methyltransferase
D9C22_13625	COG0799	negative regulation of ribosome biogenesis
D9C22_13630	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9C22_13635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9C22_13640	COG1534	Rna-binding protein
D9C22_13645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D9C22_13650	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C22_13655	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9C22_13665	COG2755	lipolytic protein G-D-S-L family
D9C22_13670	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C22_13670	COG3409	Peptidoglycan-binding domain 1 protein
D9C22_13675	COG0398	Pfam SNARE associated Golgi protein
D9C22_13680	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D9C22_13690	COG3209	COG3209 Rhs family protein
D9C22_13700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C22_13710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C22_13715	COG0798	PFAM Bile acid sodium symporter
D9C22_13720	COG0346	lactoylglutathione lyase activity
D9C22_13725	COG0640	Transcriptional regulator
D9C22_13730	COG3403	YqcI/YcgG family
D9C22_13735	COG0457	Tetratricopeptide repeat
D9C22_13750	COG5444	nuclease activity
D9C22_13775	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C22_13775	COG3409	Peptidoglycan-binding domain 1 protein
D9C22_13780	COG4824	toxin secretion phage lysis holin
D9C22_13810	COG3778	Protein conserved in bacteria
D9C22_13815	COG3299	homolog of phage Mu protein gp47
D9C22_13820	COG3628	GPW Gp25 family protein
D9C22_13830	COG4193	domain, Protein
D9C22_13835	COG1652	LysM domain
D9C22_13840	COG3953	SLT domain
D9C22_13840	COG5280	Phage tail tape measure protein TP901
D9C22_13905	COG4653	Phage capsid family
D9C22_13910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9C22_13920	COG2369	cell adhesion
D9C22_13925	COG5518	Phage portal protein
D9C22_13930	COG1783	phage Terminase large subunit
D9C22_13935	COG5484	DNA packaging
D9C22_13945	COG3677	Transposase
D9C22_13960	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D9C22_13970	COG1484	DNA-dependent DNA replication
D9C22_13975	COG3935	DnaD domain protein
D9C22_13980	COG3723	Recombinational DNA repair protein, rece pathway
D9C22_13985	COG5377	YqaJ viral recombinase family
D9C22_14015	COG1476	TRANSCRIPTIONal
D9C22_14020	COG3620	sequence-specific DNA binding
D9C22_14030	COG0563	adenylate kinase activity
D9C22_14035	COG2856	Zn peptidase
D9C22_14050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C22_14060	COG3223	Belongs to the PsiE family
D9C22_14065	COG5002	protein histidine kinase activity
D9C22_14065	COG0642	Histidine kinase
D9C22_14070	COG0745	RESPONSE REGULATOR receiver
D9C22_14075	COG2311	Membrane
D9C22_14085	COG0454	-acetyltransferase
D9C22_14090	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9C22_14100	COG0730	response to heat
D9C22_14105	COG0425	Belongs to the sulfur carrier protein TusA family
D9C22_14110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C22_14110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C22_14120	COG0425	Belongs to the sulfur carrier protein TusA family
D9C22_14120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C22_14130	COG2210	Belongs to the sulfur carrier protein TusA family
D9C22_14135	COG1937	Protein conserved in bacteria
D9C22_14150	COG0662	Cupin 2, conserved barrel domain protein
D9C22_14165	COG4978	Transcriptional regulator
D9C22_14165	COG0789	Transcriptional regulator
D9C22_14170	COG2814	Major facilitator Superfamily
D9C22_14175	COG0456	acetyltransferase
D9C22_14180	COG1253	flavin adenine dinucleotide binding
D9C22_14190	COG0697	spore germination
D9C22_14195	COG0583	DNA-binding transcription factor activity
D9C22_14200	COG2072	flavoprotein involved in K transport
D9C22_14205	COG1230	cation diffusion facilitator family transporter
D9C22_14210	COG1942	4-Oxalocrotonate Tautomerase
D9C22_14215	COG0583	DNA-binding transcription factor activity
D9C22_14225	COG1114	Component of the transport system for branched-chain amino acids
D9C22_14230	COG1687	branched-chain amino acid
D9C22_14235	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D9C22_14240	COG1522	sequence-specific DNA binding
D9C22_14245	COG2732	(Barnase) inhibitor
D9C22_14250	COG2124	cytochrome p450
D9C22_14260	COG1335	isochorismatase
D9C22_14275	COG2318	DinB family
D9C22_14285	COG2070	2-Nitropropane dioxygenase
D9C22_14300	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C22_14310	COG2186	Transcriptional regulator
D9C22_14325	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_14330	COG3958	Transketolase
D9C22_14335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9C22_14340	COG0477	Major facilitator Superfamily
D9C22_14345	COG1846	Transcriptional regulator
D9C22_14350	COG3443	Belongs to the bacterial solute-binding protein 9 family
D9C22_14355	COG1595	DNA-templated transcription, initiation
D9C22_14360	COG0667	Aldo Keto reductase
D9C22_14365	COG2851	Citrate transporter
D9C22_14370	COG0583	DNA-binding transcription factor activity
D9C22_14375	COG2828	Protein conserved in bacteria
D9C22_14380	COG3409	Peptidoglycan-binding domain 1 protein
D9C22_14385	COG5566	PFAM Mor transcription activator
D9C22_14390	COG0596	Alpha beta hydrolase
D9C22_14395	COG4991	sh3 domain protein
D9C22_14400	COG4991	sh3 domain protein
D9C22_14410	COG0346	lactoylglutathione lyase activity
D9C22_14420	COG5577	PFAM Coat F domain
D9C22_14425	COG1063	alcohol dehydrogenase
D9C22_14435	COG5577	PFAM Coat F domain
D9C22_14440	COG0789	Transcriptional regulator
D9C22_14450	COG1064	alcohol dehydrogenase
D9C22_14455	COG0693	protein deglycase activity
D9C22_14460	COG1621	beta-fructofuranosidase activity
D9C22_14465	COG3716	PTS system mannose fructose sorbose family IID component
D9C22_14470	COG3715	PTS system
D9C22_14475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_14480	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C22_14485	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C22_14485	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D9C22_14495	COG1113	amino acid transport
D9C22_14500	COG1280	lysine exporter protein (LysE YggA)
D9C22_14505	COG1378	Sugar-specific transcriptional regulator TrmB
D9C22_14510	COG1595	DNA-templated transcription, initiation
D9C22_14530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C22_14530	COG2124	cytochrome p450
D9C22_14535	COG1309	transcriptional regulator
D9C22_14540	COG2226	methyltransferase
D9C22_14555	COG2116	formate transmembrane transporter activity
D9C22_14560	COG5609	conserved protein (DUF2294)
D9C22_14565	COG3383	formate dehydrogenase (NAD+) activity
D9C22_14570	COG2427	Protein of unknown function (DUF1641)
D9C22_14580	COG0626	cystathionine gamma-synthase activity
D9C22_14585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C22_14590	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9C22_14595	COG2226	methyltransferase
D9C22_14610	COG0768	penicillin binding
D9C22_14615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9C22_14620	COG0572	uridine kinase
D9C22_14640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C22_14645	COG3906	Belongs to the UPF0473 family
D9C22_14650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9C22_14655	COG4472	Bacterial protein of unknown function (DUF965)
D9C22_14660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9C22_14665	COG0628	permease
D9C22_14670	COG1126	abc transporter atp-binding protein
D9C22_14675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C22_14680	COG0765	amino acid transport
D9C22_14685	COG0765	amino acid transport
D9C22_14700	COG3881	PFAM PRC-barrel domain
D9C22_14705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9C22_14710	COG0457	Tetratricopeptide repeat
D9C22_14715	COG0482	sulfurtransferase activity
D9C22_14720	COG1104	cysteine desulfurase activity
D9C22_14725	COG1959	2 iron, 2 sulfur cluster binding
D9C22_14730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9C22_14735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9C22_14745	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9C22_14750	COG0124	histidyl-tRNA synthetase
D9C22_14760	COG3103	Sh3 type 3 domain protein
D9C22_14760	COG4991	sh3 domain protein
D9C22_14760	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C22_14765	COG1490	D-aminoacyl-tRNA deacylase activity
D9C22_14770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9C22_14775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C22_14780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9C22_14780	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9C22_14785	COG5416	Lipopolysaccharide assembly protein A domain
D9C22_14790	COG0490	domain, Protein
D9C22_14795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C22_14795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C22_14805	COG2244	polysaccharide biosynthetic process
D9C22_14810	COG2323	membrane
D9C22_14820	COG1862	Preprotein translocase
D9C22_14825	COG0343	queuine tRNA-ribosyltransferase activity
D9C22_14830	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9C22_14840	COG2255	four-way junction helicase activity
D9C22_14845	COG0632	four-way junction helicase activity
D9C22_14855	COG2814	Major facilitator Superfamily
D9C22_14860	COG0673	inositol 2-dehydrogenase activity
D9C22_14865	COG2112	serine threonine protein kinase
D9C22_14885	COG1115	amino acid carrier protein
D9C22_14890	COG0217	transcriptional regulatory protein
D9C22_14900	COG1388	LysM domain
D9C22_14905	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D9C22_14910	COG0157	Belongs to the NadC ModD family
D9C22_14915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9C22_14920	COG1104	cysteine desulfurase activity
D9C22_14925	COG1827	regulation of RNA biosynthetic process
D9C22_14930	COG0077	Prephenate dehydratase
D9C22_14935	COG4492	Belongs to the UPF0735 family
D9C22_14940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9C22_14945	COG3290	protein histidine kinase activity
D9C22_14955	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9C22_14960	COG2868	ribosomal protein
D9C22_14965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9C22_14970	COG1994	Peptidase M50
D9C22_14975	COG0739	heme binding
D9C22_14980	COG2894	cell division
D9C22_14985	COG0850	regulation of cytokinetic process
D9C22_14990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D9C22_14995	COG1792	Involved in formation and maintenance of cell shape
D9C22_15000	COG1077	Cell shape determining protein MreB Mrl
D9C22_15010	COG0424	maF-like protein
D9C22_15020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9C22_15025	COG0285	dihydrofolate synthase activity
D9C22_15030	COG0525	valine-tRNA ligase activity
D9C22_15040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C22_15045	COG1388	LysM domain
D9C22_15050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C22_15055	COG0113	porphobilinogen synthase activity
D9C22_15060	COG1587	Uroporphyrinogen-III synthase
D9C22_15065	COG0181	hydroxymethylbilane synthase activity
D9C22_15070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C22_15075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D9C22_15085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D9C22_15090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9C22_15095	COG0470	DNA polymerase III
D9C22_15095	COG1067	ATP-dependent peptidase activity
D9C22_15100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D9C22_15105	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9C22_15110	COG1477	protein flavinylation
D9C22_15110	COG0457	Tetratricopeptide repeat
D9C22_15115	COG0066	3-isopropylmalate dehydratase activity
D9C22_15120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9C22_15125	COG0473	3-isopropylmalate dehydrogenase activity
D9C22_15130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C22_15135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9C22_15140	COG0440	acetolactate synthase activity
D9C22_15145	COG0028	Belongs to the TPP enzyme family
D9C22_15155	COG0454	-acetyltransferase
D9C22_15160	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D9C22_15170	COG0622	Phosphoesterase
D9C22_15175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9C22_15180	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D9C22_15185	COG5401	PFAM Sporulation and spore germination
D9C22_15190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C22_15195	COG1846	Transcriptional regulator
D9C22_15200	COG2197	response regulator
D9C22_15205	COG0824	Thioesterase
D9C22_15210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9C22_15215	COG1053	succinate dehydrogenase
D9C22_15220	COG2009	succinate dehydrogenase
D9C22_15225	COG1719	4-vinyl reductase, 4VR
D9C22_15230	COG0527	aspartate kinase activity
D9C22_15240	COG0322	excinuclease ABC activity
D9C22_15245	COG3118	belongs to the thioredoxin family
D9C22_15255	COG3534	alpha-L-arabinofuranosidase
D9C22_15260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9C22_15265	COG2086	electron transfer activity
D9C22_15270	COG1024	Enoyl-CoA hydratase
D9C22_15275	COG1309	transcriptional regulator
D9C22_15280	COG0318	PFAM AMP-dependent synthetase and ligase
D9C22_15285	COG3766	membrane
D9C22_15290	COG1193	negative regulation of DNA recombination
D9C22_15295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C22_15295	COG1796	DNA polymerase
D9C22_15300	COG1286	toxin biosynthetic process
D9C22_15305	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D9C22_15310	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C22_15315	COG0072	phenylalanine-tRNA ligase activity
D9C22_15315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C22_15320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9C22_15330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C22_15340	COG3835	regulator
D9C22_15345	COG0277	FAD linked oxidase domain protein
D9C22_15350	COG0247	lactate metabolic process
D9C22_15355	COG0346	lactoylglutathione lyase activity
D9C22_15365	COG1966	Carbon starvation protein
D9C22_15370	COG3534	alpha-L-arabinofuranosidase
D9C22_15375	COG0395	ABC-type sugar transport system, permease component
D9C22_15380	COG1175	transmembrane transport
D9C22_15385	COG1653	transport
D9C22_15390	COG0371	Dehydrogenase
D9C22_15395	COG0647	UMP catabolic process
D9C22_15400	COG0235	Class ii aldolase
D9C22_15405	COG1069	ribulokinase activity
D9C22_15410	COG2160	L-arabinose isomerase activity
D9C22_15415	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C22_15420	COG1363	Peptidase, m42
D9C22_15430	COG3326	Membrane
D9C22_15435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9C22_15440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D9C22_15445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9C22_15455	COG1346	cytolysis
D9C22_15460	COG1380	Effector of murein hydrolase LrgA
D9C22_15465	COG3279	Response regulator of the LytR AlgR family
D9C22_15470	COG3275	phosphorelay sensor kinase activity
D9C22_15480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C22_15490	COG0398	Pfam SNARE associated Golgi protein
D9C22_15495	COG1484	DNA-dependent DNA replication
D9C22_15500	COG3611	Membrane attachment protein
D9C22_15505	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9C22_15510	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9C22_15515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C22_15520	COG1733	regulation of RNA biosynthetic process
D9C22_15525	COG2814	Major facilitator Superfamily
D9C22_15530	COG0656	L-ascorbic acid biosynthetic process
D9C22_15535	COG0237	dephospho-CoA kinase activity
D9C22_15540	COG1971	Probably functions as a manganese efflux pump
D9C22_15545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9C22_15550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C22_15550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C22_15555	COG5002	protein histidine kinase activity
D9C22_15560	COG0745	RESPONSE REGULATOR receiver
D9C22_15565	COG0039	L-malate dehydrogenase activity
D9C22_15570	COG0538	isocitrate dehydrogenase activity
D9C22_15575	COG0372	Belongs to the citrate synthase family
D9C22_15580	COG2707	UPF0756 membrane protein
D9C22_15585	COG0628	permease
D9C22_15590	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9C22_15595	COG0469	pyruvate kinase activity
D9C22_15600	COG0205	6-phosphofructokinase activity
D9C22_15605	COG0825	malonyl-CoA metabolic process
D9C22_15610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D9C22_15615	COG0281	malic enzyme
D9C22_15620	COG0587	DNA-directed DNA polymerase activity
D9C22_15640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9C22_15650	COG4109	DRTGG domain
D9C22_15655	COG0730	response to heat
D9C22_15660	COG1473	amidohydrolase
D9C22_15665	COG0196	riboflavin kinase activity
D9C22_15670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C22_15675	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D9C22_15680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C22_15685	COG1126	abc transporter atp-binding protein
D9C22_15690	COG0765	amino acid transport
D9C22_15695	COG0765	amino acid transport
D9C22_15700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C22_15705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C22_15710	COG0454	-acetyltransferase
D9C22_15715	COG0583	DNA-binding transcription factor activity
D9C22_15720	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9C22_15725	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_15735	COG0165	Argininosuccinate lyase
D9C22_15740	COG0137	argininosuccinate synthase activity
D9C22_15745	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9C22_15750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9C22_15760	COG0827	DNA restriction-modification system
D9C22_15765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9C22_15770	COG3874	Sporulation protein YtfJ
D9C22_15780	COG1714	RDD family
D9C22_15785	COG0616	signal peptide processing
D9C22_15790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C22_15795	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D9C22_15800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C22_15810	COG0301	tRNA thio-modification
D9C22_15815	COG1104	cysteine desulfurase activity
D9C22_15820	COG1114	Component of the transport system for branched-chain amino acids
D9C22_15825	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D9C22_15830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C22_15835	COG1309	transcriptional regulator
D9C22_15840	COG1956	GAF domain-containing protein
D9C22_15845	COG2203	Gaf domain
D9C22_15845	COG2199	diguanylate cyclase activity
D9C22_15855	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9C22_15860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C22_15865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C22_15870	COG0454	-acetyltransferase
D9C22_15875	COG0517	IMP dehydrogenase activity
D9C22_15880	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9C22_15885	COG1360	Flagellar Motor Protein
D9C22_15890	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C22_15895	COG1609	Transcriptional regulator
D9C22_15900	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9C22_15900	COG1605	Chorismate mutase
D9C22_15905	COG3118	belongs to the thioredoxin family
D9C22_15910	COG4980	gas vesicle protein
D9C22_15915	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C22_15920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D9C22_15925	COG1674	ftsk spoiiie
D9C22_15930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C22_15935	COG4848	Belongs to the UPF0354 family
D9C22_15940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C22_15955	COG1363	Peptidase, m42
D9C22_15960	COG5584	Small secreted protein
D9C22_15965	COG0281	malic enzyme
D9C22_15970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C22_15975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9C22_15985	COG0510	thiamine kinase activity
D9C22_15990	COG1523	belongs to the glycosyl hydrolase 13 family
D9C22_15995	COG1597	lipid kinase activity
D9C22_16005	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C22_16010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C22_16015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C22_16020	COG2252	PERMEase
D9C22_16025	COG4473	ABC transporter
D9C22_16030	COG1131	(ABC) transporter
D9C22_16035	COG1349	DNA-binding transcription factor activity
D9C22_16040	COG1187	pseudouridine synthase activity
D9C22_16045	COG2244	polysaccharide biosynthetic process
D9C22_16050	COG2081	HI0933 family
D9C22_16055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9C22_16065	COG5578	integral membrane protein
D9C22_16070	COG0673	inositol 2-dehydrogenase activity
D9C22_16075	COG1653	transport
D9C22_16080	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C22_16085	COG4209	transmembrane transport
D9C22_16090	COG2207	Transcriptional regulator
D9C22_16095	COG1653	transport
D9C22_16100	COG0395	ABC-type sugar transport system, permease component
D9C22_16105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C22_16110	COG2124	cytochrome p450
D9C22_16115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D9C22_16125	COG0156	8-amino-7-oxononanoate synthase activity
D9C22_16130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C22_16140	COG1073	alpha beta
D9C22_16165	COG1486	melibiose metabolic process
D9C22_16170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C22_16175	COG0495	leucyl-tRNA aminoacylation
D9C22_16185	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C22_16185	COG2202	Pas domain
D9C22_16190	COG2814	Major facilitator Superfamily
D9C22_16195	COG2433	Pfam Transposase IS66
D9C22_16200	COG0577	efflux transmembrane transporter activity
D9C22_16205	COG1136	(ABC) transporter
D9C22_16210	COG2205	protein histidine kinase activity
D9C22_16215	COG0745	RESPONSE REGULATOR receiver
D9C22_16220	COG0577	efflux transmembrane transporter activity
D9C22_16225	COG1136	(ABC) transporter
D9C22_16240	COG1131	(ABC) transporter
D9C22_16245	COG1725	Transcriptional regulator
D9C22_16260	COG1242	4 iron, 4 sulfur cluster binding
D9C22_16265	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9C22_16275	COG2267	carboxylic ester hydrolase activity
D9C22_16280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9C22_16285	COG1113	amino acid transport
D9C22_16290	COG0367	asparagine synthase
D9C22_16295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9C22_16300	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D9C22_16310	COG1506	peptidase
D9C22_16315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C22_16320	COG1116	anion transmembrane transporter activity
D9C22_16325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C22_16330	COG0494	nUDIX hydrolase
D9C22_16335	COG4824	toxin secretion phage lysis holin
D9C22_16340	COG0783	Belongs to the Dps family
D9C22_16355	COG1854	S-ribosylhomocysteine lyase activity
D9C22_16360	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9C22_16365	COG0288	reversible hydration of carbon dioxide
D9C22_16370	COG0254	rRNA binding
D9C22_16375	COG1271	oxidase subunit
D9C22_16380	COG1294	oxidase, subunit
D9C22_16390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C22_16395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C22_16395	COG1321	iron dependent repressor
D9C22_16400	COG1121	(ABC) transporter
D9C22_16405	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C22_16410	COG4948	Mandelate Racemase Muconate Lactonizing
D9C22_16415	COG0318	PFAM AMP-dependent synthetase and ligase
D9C22_16420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9C22_16425	COG0596	Alpha beta hydrolase
D9C22_16430	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D9C22_16435	COG1169	isochorismate synthase
D9C22_16440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C22_16445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C22_16450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C22_16455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C22_16460	COG0438	transferase activity, transferring glycosyl groups
D9C22_16470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C22_16475	COG0438	transferase activity, transferring glycosyl groups
D9C22_16480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C22_16485	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D9C22_16490	COG0058	SHG alpha-glucan phosphorylase activity
D9C22_16495	COG0297	glycogen (starch) synthase activity
D9C22_16500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C22_16505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C22_16510	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D9C22_16635	COG3859	Proton-coupled thiamine transporter YuaJ
D9C22_16640	COG1247	-acetyltransferase
D9C22_16645	COG2268	Band 7 protein
D9C22_16650	COG1585	Membrane protein implicated in regulation of membrane protease activity
D9C22_16655	COG2318	DinB family
D9C22_16665	COG1454	alcohol dehydrogenase
D9C22_16675	COG1510	regulation of RNA biosynthetic process
D9C22_16685	COG0569	domain protein
D9C22_16690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C22_16695	COG4682	membrane
D9C22_16700	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C22_16705	COG0477	Major facilitator Superfamily
D9C22_16710	COG5553	Cysteine dioxygenase type I
D9C22_16720	COG1968	undecaprenyl-diphosphatase activity
D9C22_16725	COG0628	permease
D9C22_16730	COG0673	inositol 2-dehydrogenase activity
D9C22_16735	COG4806	L-rhamnose isomerase
D9C22_16740	COG3254	rhamnose metabolic process
D9C22_16745	COG1070	Carbohydrate kinase
D9C22_16750	COG1349	DNA-binding transcription factor activity
D9C22_16755	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_16755	COG3347	Dehydrogenase
D9C22_16765	COG0840	transmembrane signaling receptor activity
D9C22_16770	COG0840	transmembrane signaling receptor activity
D9C22_16775	COG0840	transmembrane signaling receptor activity
D9C22_16780	COG0840	transmembrane signaling receptor activity
D9C22_16795	COG0432	Pfam Uncharacterised protein family UPF0047
D9C22_16805	COG0366	Alpha amylase catalytic
D9C22_16810	COG1253	flavin adenine dinucleotide binding
D9C22_16815	COG2738	Putative neutral zinc metallopeptidase
D9C22_16830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9C22_16845	COG0166	Belongs to the GPI family
D9C22_16850	COG1979	alcohol dehydrogenase
D9C22_16855	COG1979	alcohol dehydrogenase
D9C22_16860	COG2155	Conserved Protein
D9C22_16865	COG1098	S1 RNA binding domain
D9C22_16870	COG0436	Aminotransferase
D9C22_16875	COG1522	sequence-specific DNA binding
D9C22_16880	COG2267	carboxylic ester hydrolase activity
D9C22_16890	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9C22_16895	COG2205	protein histidine kinase activity
D9C22_16905	COG5018	Exonuclease
D9C22_16915	COG2814	Major facilitator Superfamily
D9C22_16920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C22_16925	COG3011	Protein conserved in bacteria
D9C22_16935	COG3290	protein histidine kinase activity
D9C22_16940	COG4565	transcriptional regulatory protein
D9C22_16965	COG3493	citrate carrier protein
D9C22_16975	COG2111	Na H antiporter
D9C22_16975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C22_16980	COG2111	Na H antiporter
D9C22_16985	COG1006	Multisubunit Na H antiporter MnhC subunit
D9C22_16990	COG0651	ATP synthesis coupled electron transport
D9C22_16995	COG1863	multisubunit Na H antiporter MnhE subunit
D9C22_17000	COG2212	antiporter activity
D9C22_17005	COG1320	monovalent cation:proton antiporter activity
D9C22_17010	COG2050	protein possibly involved in aromatic compounds catabolism
D9C22_17015	COG2197	response regulator
D9C22_17020	COG4585	Histidine kinase
D9C22_17030	COG0142	geranyltranstransferase activity
D9C22_17045	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D9C22_17050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9C22_17055	COG1335	isochorismatase
D9C22_17060	COG5506	Protein of unknown function (DUF1694)
D9C22_17075	COG0628	permease
D9C22_17090	COG1418	mRNA catabolic process
D9C22_17095	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_17105	COG1511	domain protein
D9C22_17110	COG0433	COG0433 Predicted ATPase
D9C22_17110	COG1674	ftsk spoiiie
D9C22_17115	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C22_17120	COG5417	Belongs to the EsaB family
D9C22_17125	COG4842	Belongs to the WXG100 family
D9C22_17130	COG2508	Transcriptional regulator
D9C22_17130	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C22_17135	COG0686	Belongs to the AlaDH PNT family
D9C22_17140	COG5634	Uncharacterized conserved protein (DUF2278)
D9C22_17145	COG3251	PFAM MbtH domain protein
D9C22_17150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_17155	COG1535	isochorismatase
D9C22_17155	COG3433	isochorismatase activity
D9C22_17160	COG1021	2,3-dihydroxybenzoate-AMP ligase
D9C22_17165	COG1169	isochorismate synthase
D9C22_17170	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_17175	COG2819	hydrolase of the alpha beta superfamily
D9C22_17180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C22_17185	COG1268	BioY protein
D9C22_17190	COG2056	Na+-H+ antiporter family
D9C22_17195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9C22_17200	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9C22_17205	COG3584	3D domain protein
D9C22_17220	COG1252	NADH dehydrogenase
D9C22_17225	COG0492	ferredoxin-NADP+ reductase activity
D9C22_17235	COG0516	GMP reductase activity
D9C22_17240	COG2808	Putative FMN-binding domain
D9C22_17245	COG0456	acetyltransferase
D9C22_17250	COG0316	Belongs to the HesB IscA family
D9C22_17255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D9C22_17260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C22_17265	COG4844	belongs to the
D9C22_17270	COG1252	NADH dehydrogenase
D9C22_17275	COG4837	Protein of unknown function (DUF1462)
D9C22_17280	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9C22_17285	COG4946	Tricorn protease homolog
D9C22_17285	COG0823	Involved in the tonB-independent uptake of proteins
D9C22_17285	COG1506	peptidase
D9C22_17290	COG0083	homoserine kinase activity
D9C22_17295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9C22_17300	COG0460	homoserine dehydrogenase
D9C22_17305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C22_17310	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C22_17315	COG0647	UMP catabolic process
D9C22_17320	COG2445	Protein of unknown function DUF86
D9C22_17325	COG4470	Protein conserved in bacteria
D9C22_17335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9C22_17340	COG0739	heme binding
D9C22_17350	COG3377	Domain of unknown function (DUF1805)
D9C22_17355	COG0737	Belongs to the 5'-nucleotidase family
D9C22_17360	COG0730	response to heat
D9C22_17365	COG1801	Protein of unknown function DUF72
D9C22_17375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C22_17380	COG2508	Transcriptional regulator
D9C22_17385	COG2233	PERMEase
D9C22_17390	COG2233	PERMEase
D9C22_17395	COG3648	Uricase
D9C22_17395	COG3195	allantoin biosynthetic process
D9C22_17400	COG2351	hydroxyisourate hydrolase activity
D9C22_17410	COG2080	2 iron, 2 sulfur cluster binding
D9C22_17415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9C22_17420	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D9C22_17425	COG2068	MobA-Related Protein
D9C22_17430	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D9C22_17435	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D9C22_17440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C22_17450	COG2356	endonuclease I
D9C22_17455	COG3842	ATPase activity
D9C22_17460	COG2188	Transcriptional regulator
D9C22_17465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C22_17470	COG0395	ABC-type sugar transport system, permease component
D9C22_17475	COG1175	transmembrane transport
D9C22_17480	COG1653	transport
D9C22_17485	COG2222	sugar isomerase
D9C22_17490	COG0322	excinuclease ABC activity
D9C22_17495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C22_17510	COG0346	lactoylglutathione lyase activity
D9C22_17515	COG0640	Transcriptional regulator
D9C22_17520	COG0719	Fe-S assembly protein
D9C22_17525	COG0822	iron-sulfur transferase activity
D9C22_17530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C22_17535	COG0719	Fe-S assembly protein
D9C22_17540	COG0396	ATPase activity
D9C22_17555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9C22_17560	COG1464	Belongs to the NlpA lipoprotein family
D9C22_17565	COG2011	ABC-type metal ion transport system permease component
D9C22_17570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9C22_17580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C22_17585	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C22_17595	COG0509	glycine decarboxylation via glycine cleavage system
D9C22_17600	COG1393	Belongs to the ArsC family
D9C22_17605	COG1960	acyl-CoA dehydrogenase activity
D9C22_17610	COG0183	Belongs to the thiolase family
D9C22_17615	COG1024	Enoyl-CoA hydratase
D9C22_17615	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C22_17625	COG0506	proline dehydrogenase activity
D9C22_17635	COG5577	PFAM Coat F domain
D9C22_17640	COG1846	Transcriptional regulator
D9C22_17645	COG0477	Major facilitator Superfamily
D9C22_17650	COG1942	4-Oxalocrotonate Tautomerase
D9C22_17660	COG0583	DNA-binding transcription factor activity
D9C22_17670	COG1120	ATPase activity
D9C22_17685	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_17690	COG0783	Belongs to the Dps family
D9C22_17695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C22_17700	COG0745	RESPONSE REGULATOR receiver
D9C22_17705	COG2205	protein histidine kinase activity
D9C22_17705	COG2770	Histidine kinase
D9C22_17715	COG1309	transcriptional regulator
D9C22_17720	COG0114	fumarate hydratase activity
D9C22_17730	COG0697	spore germination
D9C22_17735	COG0814	amino acid
D9C22_17745	COG2197	response regulator
D9C22_17750	COG4585	Histidine kinase
D9C22_17755	COG4758	membrane
D9C22_17760	COG3595	metallopeptidase activity
D9C22_17765	COG1842	Phage shock protein A
D9C22_17770	COG4758	membrane
D9C22_17775	COG2814	Major facilitator Superfamily
D9C22_17780	COG2096	Adenosyltransferase
D9C22_17785	COG1120	ATPase activity
D9C22_17790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C22_17795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C22_17800	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_17805	COG3386	PFAM SMP-30 Gluconolaconase
D9C22_17810	COG2205	protein histidine kinase activity
D9C22_17815	COG0745	RESPONSE REGULATOR receiver
D9C22_17825	COG1191	sigma factor activity
D9C22_17835	COG2140	Oxalate decarboxylase
D9C22_17845	COG0577	efflux transmembrane transporter activity
D9C22_17850	COG1136	(ABC) transporter
D9C22_17855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C22_17860	COG1120	ATPase activity
D9C22_17865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C22_17870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C22_17875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C22_17885	COG0531	amino acid
D9C22_17900	COG1988	membrane-bound metal-dependent
D9C22_17905	COG1368	sulfuric ester hydrolase activity
D9C22_17910	COG1910	domain protein
D9C22_17915	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9C22_17920	COG4149	molybdate abc transporter
D9C22_17925	COG0656	L-ascorbic acid biosynthetic process
D9C22_17935	COG0025	NhaP-type Na H and K H
D9C22_17940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C22_17945	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C22_17950	COG3973	AAA domain
D9C22_17960	COG2860	membrane
D9C22_17965	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9C22_17970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D9C22_17975	COG2217	Heavy metal translocating P-type atpase
D9C22_17980	COG2217	Heavy metal translocating P-type atpase
D9C22_17985	COG2608	mercury ion transmembrane transporter activity
D9C22_17990	COG1937	Protein conserved in bacteria
D9C22_17995	COG0673	inositol 2-dehydrogenase activity
D9C22_18000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9C22_18005	COG1289	transmembrane transporter activity
D9C22_18015	COG2076	Multidrug Resistance protein
D9C22_18020	COG1309	transcriptional regulator
D9C22_18025	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_18050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D9C22_18055	COG0557	exoribonuclease II activity
D9C22_18060	COG1647	Serine aminopeptidase, S33
D9C22_18065	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C22_18070	COG0596	Alpha beta hydrolase
D9C22_18075	COG1476	TRANSCRIPTIONal
D9C22_18080	COG1396	sequence-specific DNA binding
D9C22_18085	COG1396	sequence-specific DNA binding
D9C22_18090	COG1733	regulation of RNA biosynthetic process
D9C22_18095	COG0840	transmembrane signaling receptor activity
D9C22_18150	COG1174	glycine betaine transport
D9C22_18155	COG1732	Glycine betaine
D9C22_18160	COG1174	glycine betaine transport
D9C22_18165	COG0517	IMP dehydrogenase activity
D9C22_18165	COG1125	glycine betaine transport
D9C22_18170	COG1510	regulation of RNA biosynthetic process
D9C22_18175	COG1174	glycine betaine transport
D9C22_18180	COG1732	Glycine betaine
D9C22_18185	COG1174	glycine betaine transport
D9C22_18190	COG1125	glycine betaine transport
D9C22_18190	COG0517	IMP dehydrogenase activity
D9C22_18195	COG1510	regulation of RNA biosynthetic process
D9C22_18200	COG2095	MarC family integral membrane protein
D9C22_18210	COG3064	Membrane
D9C22_18215	COG4640	response to antibiotic
D9C22_18220	COG0456	acetyltransferase
D9C22_18225	COG0148	phosphopyruvate hydratase activity
D9C22_18230	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D9C22_18235	COG0149	triose-phosphate isomerase activity
D9C22_18240	COG0126	phosphoglycerate kinase activity
D9C22_18245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C22_18250	COG2390	Transcriptional regulator
D9C22_18255	COG2814	Major facilitator Superfamily
D9C22_18260	COG1609	Transcriptional regulator
D9C22_18265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C22_18275	COG0583	DNA-binding transcription factor activity
D9C22_18280	COG0697	spore germination
D9C22_18285	COG1113	amino acid transport
D9C22_18290	COG3858	chitin binding
D9C22_18295	COG1556	Lactate utilization protein
D9C22_18300	COG1139	Iron-sulfur cluster binding protein
D9C22_18305	COG0247	lactate metabolic process
D9C22_18310	COG2197	response regulator
D9C22_18315	COG4585	Histidine kinase
D9C22_18320	COG0842	Transport permease protein
D9C22_18325	COG1131	(ABC) transporter
D9C22_18330	COG0596	Alpha beta hydrolase
D9C22_18335	COG2208	phosphoserine phosphatase activity
D9C22_18340	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D9C22_18345	COG1874	Beta-galactosidase
D9C22_18350	COG3833	ABC-type maltose transport systems, permease component
D9C22_18355	COG1175	transmembrane transport
D9C22_18360	COG2182	Extracellular solute-binding protein
D9C22_18365	COG1609	Transcriptional regulator
D9C22_18370	COG2186	Transcriptional regulator
D9C22_18375	COG1620	l-lactate permease
D9C22_18385	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D9C22_18395	COG5039	Polysaccharide pyruvyl transferase
D9C22_18400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C22_18405	COG0110	maltose O-acetyltransferase activity
D9C22_18410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9C22_18415	COG2244	polysaccharide biosynthetic process
D9C22_18420	COG1216	Glycosyl transferase, family 2
D9C22_18425	COG5039	Polysaccharide pyruvyl transferase
D9C22_18430	COG1216	Glycosyl transferase, family 2
D9C22_18440	COG0438	transferase activity, transferring glycosyl groups
D9C22_18445	COG1215	transferase activity, transferring glycosyl groups
D9C22_18450	COG0438	transferase activity, transferring glycosyl groups
D9C22_18455	COG1086	Polysaccharide biosynthesis protein
D9C22_18460	COG0489	protein tyrosine kinase activity
D9C22_18465	COG3944	biosynthesis protein
D9C22_18470	COG1396	sequence-specific DNA binding
D9C22_18475	COG2272	Belongs to the type-B carboxylesterase lipase family
D9C22_18485	COG3479	Phenolic acid decarboxylase
D9C22_18495	COG1794	racemase activity, acting on amino acids and derivatives
D9C22_18500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C22_18505	COG1621	beta-fructofuranosidase activity
D9C22_18510	COG1621	beta-fructofuranosidase activity
D9C22_18515	COG0531	amino acid
D9C22_18520	COG1309	transcriptional regulator
D9C22_18525	COG2076	Multidrug Resistance protein
D9C22_18530	COG2076	Multidrug Resistance protein
D9C22_18545	COG0740	serine-type endopeptidase activity
D9C22_18550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C22_18555	COG0366	Alpha amylase catalytic
D9C22_18560	COG1554	hydrolase, family 65, central catalytic
D9C22_18565	COG5521	maltodextrose utilization protein MalA
D9C22_18570	COG3833	ABC-type maltose transport systems, permease component
D9C22_18575	COG1175	transmembrane transport
D9C22_18580	COG2182	Extracellular solute-binding protein
D9C22_18585	COG0366	Alpha amylase catalytic
D9C22_18590	COG1609	Transcriptional regulator
D9C22_18595	COG1611	Belongs to the LOG family
D9C22_18600	COG1694	Mazg nucleotide pyrophosphohydrolase
D9C22_18605	COG0659	secondary active sulfate transmembrane transporter activity
D9C22_18610	COG0288	reversible hydration of carbon dioxide
D9C22_18615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C22_18620	COG0577	efflux transmembrane transporter activity
D9C22_18625	COG1136	(ABC) transporter
D9C22_18630	COG5002	protein histidine kinase activity
D9C22_18635	COG0745	RESPONSE REGULATOR receiver
D9C22_18650	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D9C22_18655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C22_18660	COG1481	regulation of sporulation
D9C22_18665	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9C22_18670	COG1660	Displays ATPase and GTPase activities
D9C22_18675	COG1051	belongs to the nudix hydrolase family
D9C22_18680	COG0492	ferredoxin-NADP+ reductase activity
D9C22_18685	COG3883	PFAM NLP P60 protein
D9C22_18685	COG0791	NLP P60 protein
D9C22_18690	COG0457	Tetratricopeptide repeat
D9C22_18695	COG1132	(ABC) transporter
D9C22_18715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9C22_18715	COG0140	phosphoribosyl-ATP diphosphatase activity
D9C22_18720	COG0107	imidazoleglycerol-phosphate synthase activity
D9C22_18725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9C22_18730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9C22_18735	COG0131	Imidazoleglycerol-phosphate dehydratase
D9C22_18740	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9C22_18745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9C22_18750	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D9C22_18755	COG4990	cell redox homeostasis
D9C22_18760	COG5297	Belongs to the glycosyl hydrolase family 6
D9C22_18765	COG0110	maltose O-acetyltransferase activity
D9C22_18770	COG0546	phosphoglycolate phosphatase activity
D9C22_18775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9C22_18780	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D9C22_18785	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9C22_18790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9C22_18795	COG0363	glucosamine-6-phosphate deaminase activity
D9C22_18805	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9C22_18810	COG1846	Transcriptional regulator
D9C22_18825	COG1846	Transcriptional regulator
D9C22_18830	COG2814	Major facilitator Superfamily
D9C22_18835	COG1950	PFAM Membrane protein of
D9C22_18840	COG1983	PspC domain protein
D9C22_18845	COG3595	metallopeptidase activity
D9C22_18865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9C22_18870	COG0556	nucleotide-excision repair
D9C22_18875	COG4897	Protein conserved in bacteria
D9C22_18880	COG0574	Belongs to the PEP-utilizing enzyme family
D9C22_18880	COG3848	Pyruvate phosphate dikinase
D9C22_18885	COG1309	transcriptional regulator
D9C22_18890	COG2814	Major facilitator Superfamily
D9C22_18895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C22_18905	COG0793	Belongs to the peptidase S41A family
D9C22_18905	COG3409	Peptidoglycan-binding domain 1 protein
D9C22_18910	COG2177	Part of the ABC transporter FtsEX involved in
D9C22_18915	COG2884	Cell division ATP-binding protein ftsE
D9C22_18920	COG2010	Cytochrome c
D9C22_18925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C22_18935	COG0653	protein targeting
D9C22_18940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D9C22_18955	COG1516	flagellar protein fliS
D9C22_18960	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9C22_18965	COG1334	flagellar protein FlaG
D9C22_18970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C22_18975	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9C22_18980	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D9C22_18990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C22_18995	COG4786	Flagellar basal body rod
D9C22_18995	COG1256	bacterial-type flagellum assembly
D9C22_19000	COG3418	PFAM FlgN family protein
D9C22_19005	COG2747	anti-sigma28 factor FlgM
D9C22_19015	COG1040	competence protein
D9C22_19025	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D9C22_19030	COG1307	EDD domain protein, DegV family
D9C22_19035	COG2197	response regulator
D9C22_19040	COG4585	Histidine kinase
D9C22_19045	COG1739	Uncharacterized protein family UPF0029
D9C22_19050	COG1316	TRANSCRIPTIONal
D9C22_19055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C22_19060	COG0438	transferase activity, transferring glycosyl groups
D9C22_19065	COG1215	transferase activity, transferring glycosyl groups
D9C22_19070	COG3206	protein involved in exopolysaccharide biosynthesis
D9C22_19075	COG3307	-O-antigen
D9C22_19080	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C22_19085	COG0438	transferase activity, transferring glycosyl groups
D9C22_19085	COG0297	glycogen (starch) synthase activity
D9C22_19090	COG2244	polysaccharide biosynthetic process
D9C22_19105	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C22_19105	COG2247	cell wall binding repeat
D9C22_19110	COG2385	sporulation resulting in formation of a cellular spore
D9C22_19110	COG2247	cell wall binding repeat
D9C22_19120	COG1316	TRANSCRIPTIONal
D9C22_19125	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9C22_19145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C22_19155	COG1682	transport, permease protein
D9C22_19160	COG1215	transferase activity, transferring glycosyl groups
D9C22_19160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C22_19165	COG0463	Glycosyl transferase, family 2
D9C22_19210	COG4193	domain, Protein
D9C22_19215	COG1482	cell wall glycoprotein biosynthetic process
D9C22_19220	COG0697	spore germination
D9C22_19225	COG0814	amino acid
D9C22_19235	COG2814	Major facilitator Superfamily
D9C22_19240	COG1316	TRANSCRIPTIONal
D9C22_19245	COG0561	phosphatase activity
D9C22_19250	COG0791	NLP P60 protein
D9C22_19260	COG2843	Capsule synthesis protein
D9C22_19270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C22_19275	COG1609	Transcriptional regulator
D9C22_19280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C22_19285	COG1869	D-ribose catabolic process
D9C22_19290	COG1129	ABC transporter
D9C22_19295	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9C22_19300	COG1879	ABC-type sugar transport system periplasmic component
D9C22_19305	COG3103	Sh3 type 3 domain protein
D9C22_19315	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9C22_19320	COG3527	Alpha-acetolactate decarboxylase
D9C22_19325	COG0028	Belongs to the TPP enzyme family
D9C22_19330	COG0583	DNA-binding transcription factor activity
D9C22_19335	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9C22_19350	COG5337	Spore coat protein CotH
D9C22_19360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C22_19370	COG0405	Gamma-glutamyltransferase
D9C22_19375	COG1522	sequence-specific DNA binding
D9C22_19380	COG2059	Chromate
D9C22_19385	COG2059	Chromate
D9C22_19420	COG3878	Protein conserved in bacteria
D9C22_19425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C22_19430	COG4464	protein tyrosine phosphatase activity
D9C22_19435	COG0489	protein tyrosine kinase activity
D9C22_19440	COG3944	biosynthesis protein
D9C22_19450	COG4715	Zinc finger, swim domain protein
D9C22_19455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C22_19465	COG0561	phosphatase activity
D9C22_19470	COG1349	DNA-binding transcription factor activity
D9C22_19475	COG0629	single-stranded DNA binding
D9C22_19490	COG3764	Sortase (surface protein transpeptidase)
D9C22_19500	COG3279	Response regulator of the LytR AlgR family
D9C22_19510	COG1970	mechanosensitive ion channel activity
D9C22_19515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C22_19520	COG0457	Tetratricopeptide repeat
D9C22_19525	COG4786	Flagellar basal body rod
D9C22_19530	COG4786	Flagellar basal body rod
D9C22_19535	COG1077	Cell shape determining protein MreB Mrl
D9C22_19540	COG1609	Transcriptional regulator
D9C22_19550	COG1846	Transcriptional regulator
D9C22_19555	COG2814	Major facilitator Superfamily
D9C22_19560	COG3420	alginic acid biosynthetic process
D9C22_19565	COG1953	Uracil, thiamine, allantoin
D9C22_19570	COG0477	Major facilitator Superfamily
D9C22_19575	COG1335	isochorismatase
D9C22_19585	COG0004	ammonium transporteR
D9C22_19590	COG0347	Belongs to the P(II) protein family
D9C22_19595	COG0671	phosphoesterase, PA-phosphatase related
D9C22_19605	COG0739	heme binding
D9C22_19610	COG1247	-acetyltransferase
D9C22_19630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C22_19635	COG0789	Transcriptional regulator
D9C22_19645	COG2910	NAD(P)H-binding
D9C22_19650	COG1959	2 iron, 2 sulfur cluster binding
D9C22_19655	COG0804	urea catabolic process
D9C22_19660	COG0832	Belongs to the urease beta subunit family
D9C22_19665	COG0831	urea catabolic process
D9C22_19680	COG3237	CsbD-like
D9C22_19685	COG1994	Peptidase M50
D9C22_19690	COG0457	Tetratricopeptide repeat
D9C22_19700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9C22_19705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9C22_19715	COG2304	oxidoreductase activity
D9C22_19725	COG2304	oxidoreductase activity
D9C22_19730	COG2385	sporulation resulting in formation of a cellular spore
D9C22_19735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C22_19745	COG4836	Membrane
D9C22_19755	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D9C22_19760	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9C22_19765	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9C22_19770	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D9C22_19775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C22_19780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9C22_19785	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C22_19790	COG0356	it plays a direct role in the translocation of protons across the membrane
D9C22_19800	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9C22_19805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9C22_19810	COG4475	Protein of unknown function (DUF436)
D9C22_19815	COG0698	ribose 5-phosphate isomerase
D9C22_19820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C22_19825	COG1971	Probably functions as a manganese efflux pump
D9C22_19830	COG0009	L-threonylcarbamoyladenylate synthase
D9C22_19835	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D9C22_19855	COG2890	protein-(glutamine-N5) methyltransferase activity
D9C22_19860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9C22_19865	COG0346	lactoylglutathione lyase activity
D9C22_19870	COG0789	Transcriptional regulator
D9C22_19875	COG0679	Auxin Efflux Carrier
D9C22_19880	COG0281	malic enzyme
D9C22_19885	COG1435	thymidine kinase activity
D9C22_19890	COG0254	rRNA binding
D9C22_19895	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9C22_19905	COG1494	fructose-1,6-bisphosphatase
D9C22_19910	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C22_19915	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9C22_19920	COG0191	fructose-bisphosphate aldolase activity
D9C22_19925	COG2204	response regulator
D9C22_19930	COG4821	SIS domain
D9C22_19935	COG0504	CTP synthase activity
D9C22_19940	COG3343	RNA polymerase activity
D9C22_19945	COG1960	acyl-CoA dehydrogenase activity
D9C22_19950	COG0247	lactate metabolic process
D9C22_19950	COG2181	nitrate reductase activity
D9C22_19955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C22_19960	COG4294	response to UV
D9C22_19970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C22_19975	COG1132	(ABC) transporter
D9C22_19980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C22_19990	COG2181	nitrate reductase activity
D9C22_19995	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D9C22_20000	COG1140	nitrate reductase beta subunit
D9C22_20005	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D9C22_20010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9C22_20020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9C22_20025	COG2223	nitrite transmembrane transporter activity
D9C22_20030	COG0018	arginyl-trna synthetase
D9C22_20035	COG4506	Protein conserved in bacteria
D9C22_20050	COG0535	radical SAM domain protein
D9C22_20060	COG1131	(ABC) transporter
D9C22_20065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C22_20070	COG0612	Peptidase, M16
D9C22_20075	COG0612	Peptidase, M16
D9C22_20085	COG3391	amine dehydrogenase activity
D9C22_20090	COG3391	amine dehydrogenase activity
D9C22_20100	COG0457	Tetratricopeptide repeat
D9C22_20130	COG1131	(ABC) transporter
D9C22_20140	COG0010	Belongs to the arginase family
D9C22_20145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9C22_20150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C22_20165	COG1994	Peptidase M50
D9C22_20170	COG1942	4-Oxalocrotonate Tautomerase
D9C22_20175	COG1846	Transcriptional regulator
D9C22_20180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C22_20190	COG0477	Major facilitator Superfamily
D9C22_20195	COG1959	2 iron, 2 sulfur cluster binding
D9C22_20200	COG3465	dGTPase activity
D9C22_20205	COG1078	dGTPase activity
D9C22_20210	COG4844	belongs to the
D9C22_20220	COG0697	spore germination
D9C22_20225	COG0095	Lipoate-protein ligase
D9C22_20230	COG0583	DNA-binding transcription factor activity
D9C22_20235	COG0280	phosphate acetyltransferase
D9C22_20245	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_20250	COG0436	Aminotransferase
D9C22_20255	COG2814	Major facilitator Superfamily
D9C22_20260	COG0151	Belongs to the GarS family
D9C22_20265	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_20270	COG1917	Cupin 2, conserved barrel domain protein
D9C22_20275	COG0077	Prephenate dehydratase
D9C22_20280	COG2814	Major facilitator Superfamily
D9C22_20285	COG0833	amino acid
D9C22_20290	COG4187	Peptidase family M20/M25/M40
D9C22_20295	COG1012	belongs to the aldehyde dehydrogenase family
D9C22_20300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C22_20310	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D9C22_20315	COG1091	dTDP-4-dehydrorhamnose reductase activity
D9C22_20320	COG1088	dTDP-glucose 4,6-dehydratase activity
D9C22_20325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D9C22_20330	COG3980	spore coat polysaccharide biosynthesis protein
D9C22_20335	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D9C22_20340	COG2089	acid synthase
D9C22_20345	COG0456	acetyltransferase
D9C22_20350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C22_20355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C22_20360	COG0463	Glycosyl transferase, family 2
D9C22_20375	COG2363	Small membrane protein
D9C22_20380	COG2233	PERMEase
D9C22_20390	COG1012	belongs to the aldehyde dehydrogenase family
D9C22_20395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9C22_20400	COG1216	Glycosyl transferase, family 2
D9C22_20415	COG1695	Transcriptional regulator
D9C22_20420	COG0351	phosphomethylpyrimidine kinase
D9C22_20430	COG1621	beta-fructofuranosidase activity
D9C22_20435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_20435	COG1263	PTS System
D9C22_20440	COG2116	formate transmembrane transporter activity
D9C22_20445	COG3711	transcriptional antiterminator
D9C22_20455	COG1404	Belongs to the peptidase S8 family
D9C22_20460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C22_20465	COG0778	Nitroreductase
D9C22_20470	COG0772	Belongs to the SEDS family
D9C22_20480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C22_20485	COG1845	cytochrome c oxidase, subunit III
D9C22_20490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C22_20495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C22_20500	COG2261	transglycosylase associated protein
D9C22_20505	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9C22_20510	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9C22_20515	COG2246	polysaccharide biosynthetic process
D9C22_20520	COG1309	transcriptional regulator
D9C22_20530	COG3162	membrane
D9C22_20535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C22_20540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9C22_20545	COG2837	iron assimilation
D9C22_20550	COG2822	iron ion transport
D9C22_20555	COG0672	)-iron permease
D9C22_20560	COG0352	thiamine-phosphate diphosphorylase activity
D9C22_20565	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D9C22_20570	COG0583	DNA-binding transcription factor activity
D9C22_20575	COG1380	Effector of murein hydrolase LrgA
D9C22_20580	COG1346	cytolysis
D9C22_20585	COG2814	Major facilitator Superfamily
D9C22_20590	COG4895	conserved protein (DUF2196)
D9C22_20595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9C22_20600	COG0346	lactoylglutathione lyase activity
D9C22_20615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C22_20620	COG1404	Belongs to the peptidase S8 family
D9C22_20625	COG1263	PTS System
D9C22_20625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_20630	COG3711	transcriptional antiterminator
D9C22_20635	COG1442	glycosyl transferase family 8
D9C22_20640	COG5522	Integral membrane protein (intg_mem_TP0381)
D9C22_20645	COG1846	Transcriptional regulator
D9C22_20650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C22_20655	COG2234	aminopeptidase activity
D9C22_20670	COG2814	Major facilitator Superfamily
D9C22_20675	COG2357	RelA SpoT domain protein
D9C22_20680	COG1575	Belongs to the MenA family. Type 1 subfamily
D9C22_20700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C22_20705	COG1696	Membrane protein involved in D-alanine export
D9C22_20710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C22_20715	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D9C22_20720	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D9C22_20725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C22_20730	COG1486	melibiose metabolic process
D9C22_20735	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9C22_20740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C22_20745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C22_20750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C22_20750	COG3711	transcriptional antiterminator
D9C22_20760	COG2094	Belongs to the DNA glycosylase MPG family
D9C22_20765	COG0753	catalase activity
D9C22_20770	COG2814	Major facilitator Superfamily
D9C22_20775	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C22_20780	COG1131	(ABC) transporter
D9C22_20800	COG1595	DNA-templated transcription, initiation
D9C22_20805	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C22_20810	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D9C22_20815	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D9C22_20820	COG4988	ABC transporter
D9C22_20825	COG1294	oxidase, subunit
D9C22_20830	COG1271	oxidase subunit
D9C22_20835	COG3493	citrate carrier protein
D9C22_20840	COG0501	Belongs to the peptidase M48B family
D9C22_20850	COG0726	polysaccharide deacetylase
D9C22_20870	COG2508	Transcriptional regulator
D9C22_20875	COG1012	belongs to the aldehyde dehydrogenase family
D9C22_20880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C22_20890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9C22_20895	COG1881	PFAM PEBP family protein
D9C22_20900	COG0583	DNA-binding transcription factor activity
D9C22_20910	COG4585	Histidine kinase
D9C22_20915	COG2197	response regulator
D9C22_20920	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C22_20930	COG4894	glucomannan catabolic process
D9C22_20935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C22_20940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C22_20945	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_20950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9C22_20955	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C22_20960	COG2610	gluconate transmembrane transporter activity
D9C22_20965	COG0500	methyltransferase
D9C22_20970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C22_20985	COG0753	catalase activity
D9C22_20985	COG0693	protein deglycase activity
D9C22_20990	COG2851	Citrate transporter
D9C22_20995	COG2273	Hydrolase Family 16
D9C22_21000	COG3711	transcriptional antiterminator
D9C22_21010	COG2270	Major facilitator Superfamily
D9C22_21015	COG0513	Belongs to the DEAD box helicase family
D9C22_21020	COG3401	FG-GAP repeat protein
D9C22_21020	COG2755	lipolytic protein G-D-S-L family
D9C22_21065	COG3209	COG3209 Rhs family protein
D9C22_21070	COG0697	spore germination
D9C22_21075	COG0589	response to stress
D9C22_21080	COG2723	6-phospho-beta-galactosidase activity
D9C22_21085	COG1263	PTS System
D9C22_21085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_21085	COG2190	(PTS) system
D9C22_21140	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C22_21155	COG2986	histidine ammonia-lyase
D9C22_21160	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D9C22_21165	COG1228	amidohydrolase
D9C22_21170	COG0010	Belongs to the arginase family
D9C22_21175	COG0833	amino acid
D9C22_21180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D9C22_21185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C22_21190	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9C22_21195	COG2390	Transcriptional regulator
D9C22_21205	COG3192	ethanolamine utilization protein
D9C22_21210	COG2079	MmgE PrpD family protein
D9C22_21220	COG1126	abc transporter atp-binding protein
D9C22_21225	COG0765	amino acid transport
D9C22_21230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C22_21245	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D9C22_21250	COG0561	phosphatase activity
D9C22_21280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C22_21285	COG5294	Protein conserved in bacteria
D9C22_21290	COG0577	efflux transmembrane transporter activity
D9C22_21295	COG1136	(ABC) transporter
D9C22_21300	COG2205	protein histidine kinase activity
D9C22_21305	COG0745	RESPONSE REGULATOR receiver
D9C22_21310	COG0191	fructose-bisphosphate aldolase activity
D9C22_21315	COG1082	Xylose isomerase domain protein TIM barrel
D9C22_21320	COG1082	Xylose isomerase domain protein TIM barrel
D9C22_21325	COG0673	inositol 2-dehydrogenase activity
D9C22_21330	COG2814	Major facilitator Superfamily
D9C22_21335	COG1082	Xylose isomerase domain protein TIM barrel
D9C22_21340	COG3962	Belongs to the TPP enzyme family
D9C22_21345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C22_21355	COG1012	belongs to the aldehyde dehydrogenase family
D9C22_21360	COG1349	DNA-binding transcription factor activity
D9C22_21365	COG0667	Aldo Keto reductase
D9C22_21380	COG2814	Major facilitator Superfamily
D9C22_21385	COG0326	Molecular chaperone. Has ATPase activity
D9C22_21395	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_21425	COG1309	transcriptional regulator
D9C22_21430	COG1012	belongs to the aldehyde dehydrogenase family
D9C22_21435	COG1714	RDD family
D9C22_21440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D9C22_21450	COG1714	RDD family
D9C22_21455	COG2311	Membrane
D9C22_21460	COG1917	Cupin 2, conserved barrel domain protein
D9C22_21465	COG1309	transcriptional regulator
D9C22_21470	COG1028	Short-chain dehydrogenase reductase Sdr
D9C22_21475	COG1846	Transcriptional regulator
D9C22_21480	COG1380	Effector of murein hydrolase LrgA
D9C22_21485	COG1346	cytolysis
D9C22_21490	COG5039	Polysaccharide pyruvyl transferase
D9C22_21495	COG1929	Belongs to the glycerate kinase type-1 family
D9C22_21500	COG1802	Transcriptional regulator
D9C22_21505	COG1070	Carbohydrate kinase
D9C22_21510	COG2610	gluconate transmembrane transporter activity
D9C22_21515	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C22_21520	COG0450	alkyl hydroperoxide reductase
D9C22_21525	COG3634	alkyl hydroperoxide reductase activity
D9C22_21545	COG1263	PTS System
D9C22_21545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C22_21550	COG2188	Transcriptional regulator
D9C22_21565	COG1131	(ABC) transporter
D9C22_21570	COG1994	Peptidase M50
D9C22_21575	COG0535	radical SAM domain protein
D9C22_21585	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D9C22_21595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D9C22_21610	COG1063	alcohol dehydrogenase
D9C22_21630	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D9C22_21635	COG0456	acetyltransferase
D9C22_21640	COG0457	Tetratricopeptide repeat
D9C22_21650	COG0010	Belongs to the arginase family
D9C22_21655	COG0833	amino acid
D9C22_21660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C22_21665	COG3829	transcription factor binding
D9C22_21680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C22_21685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9C22_21690	COG4853	Protein conserved in bacteria
D9C22_21695	COG4863	YycH protein
D9C22_21700	COG5002	protein histidine kinase activity
D9C22_21705	COG0745	RESPONSE REGULATOR receiver
D9C22_21735	COG0346	lactoylglutathione lyase activity
D9C22_21740	COG0305	Participates in initiation and elongation during chromosome replication
D9C22_21755	COG3093	addiction module antidote protein HigA
D9C22_21760	COG2807	transmembrane transport
D9C22_21765	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C22_21770	COG0359	binds to the 23S rRNA
D9C22_21775	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9C22_21780	COG4241	membrane
D9C22_21790	COG5577	PFAM Coat F domain
D9C22_21795	COG1733	regulation of RNA biosynthetic process
D9C22_21800	COG1227	inorganic diphosphatase activity
D9C22_21815	COG2271	Major facilitator Superfamily
D9C22_21820	COG0789	Transcriptional regulator
D9C22_21820	COG4978	Transcriptional regulator
D9C22_21830	COG4319	ketosteroid isomerase
D9C22_21840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C22_21845	COG1846	Transcriptional regulator
D9C22_21850	COG2153	protein acetylation
D9C22_21855	COG2364	Membrane
D9C22_21860	COG0456	acetyltransferase
D9C22_21865	COG2315	Protein conserved in bacteria
D9C22_21870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C22_21890	COG0789	Transcriptional regulator
D9C22_21895	COG0697	spore germination
D9C22_21900	COG1331	Highly conserved protein containing a thioredoxin domain
D9C22_21905	COG1266	CAAX protease self-immunity
D9C22_21910	COG0477	Major facilitator Superfamily
D9C22_21910	COG2814	Major facilitator Superfamily
D9C22_21915	COG0110	maltose O-acetyltransferase activity
D9C22_21920	COG0346	lactoylglutathione lyase activity
D9C22_21925	COG1609	Transcriptional regulator
D9C22_21930	COG0708	Exodeoxyribonuclease III
D9C22_21935	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D9C22_21940	COG0629	single-stranded DNA binding
D9C22_21945	COG0360	Binds together with S18 to 16S ribosomal RNA
D9C22_21950	COG0012	GTP binding
D9C22_21955	COG0243	molybdopterin cofactor binding
D9C22_21960	COG4481	Protein conserved in bacteria
D9C22_21965	COG3949	Membrane
D9C22_21975	COG1475	DNA binding
D9C22_21980	COG1192	Involved in chromosome partitioning
D9C22_21990	COG1475	DNA binding
D9C22_21995	COG0357	Ribosomal RNA small subunit methyltransferase G
D9C22_22000	COG0445	tRNA wobble uridine modification
D9C22_22005	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D9C22_22010	COG1847	R3H domain protein
D9C22_22015	COG0706	membrane insertase activity
D9C22_22020	COG0594	ribonuclease P activity
D9C22_22025	COG0230	Belongs to the bacterial ribosomal protein bL34 family