HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 SMART SM01210 325 418 3.4E-40 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 SMART SM01209 101 293 8.3E-128 T 12-10-2018 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 Gene3D G3DSA:3.30.470.20 189 324 3.8E-54 T 12-10-2018 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 Gene3D G3DSA:3.90.600.10 325 421 7.3E-32 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 SUPERFAMILY SSF51246 324 418 1.1E-26 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 Gene3D G3DSA:3.30.1490.20 119 188 5.2E-27 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 12-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 418 1.8E-162 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 Gene3D G3DSA:3.40.50.20 1 93 7.8E-34 T 12-10-2018 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 418 42.434 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 SUPERFAMILY SSF52440 2 101 5.61E-32 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 327 415 2.9E-26 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 SUPERFAMILY SSF56059 102 317 7.07E-61 T 12-10-2018 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 2.9E-31 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11735 ee5addb4a5bd205e93f2d108fb10bde7 421 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 1.2E-79 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_06605 854419145c808f9e02ecd0deb750d531 547 SUPERFAMILY SSF55021 452 526 1.21E-15 T 12-10-2018 HW35_06605 854419145c808f9e02ecd0deb750d531 547 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 HW35_06605 854419145c808f9e02ecd0deb750d531 547 Gene3D G3DSA:3.40.50.720 94 283 1.6E-121 T 12-10-2018 HW35_06605 854419145c808f9e02ecd0deb750d531 547 SUPERFAMILY SSF51735 101 282 5.0E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_06605 854419145c808f9e02ecd0deb750d531 547 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 1.7E-63 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HW35_06605 854419145c808f9e02ecd0deb750d531 547 SUPERFAMILY SSF52283 24 129 1.23E-37 T 12-10-2018 HW35_06605 854419145c808f9e02ecd0deb750d531 547 Gene3D G3DSA:3.40.50.720 4 292 1.6E-121 T 12-10-2018 HW35_06605 854419145c808f9e02ecd0deb750d531 547 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 527 1.0E-207 T 12-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 HW35_06605 854419145c808f9e02ecd0deb750d531 547 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site HW35_06605 854419145c808f9e02ecd0deb750d531 547 SUPERFAMILY SSF143548 320 450 2.09E-27 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 HW35_06605 854419145c808f9e02ecd0deb750d531 547 Gene3D G3DSA:3.30.70.260 455 529 3.5E-19 T 12-10-2018 HW35_06605 854419145c808f9e02ecd0deb750d531 547 Gene3D G3DSA:3.30.1330.90 318 454 3.6E-30 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 HW35_06605 854419145c808f9e02ecd0deb750d531 547 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 313 2.3E-37 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 HW35_06720 ed39c724b5e0ffc11a887e519f606856 312 Gene3D G3DSA:3.30.460.20 4 132 4.3E-25 T 12-10-2018 HW35_06720 ed39c724b5e0ffc11a887e519f606856 312 SUPERFAMILY SSF144083 248 310 1.57E-15 T 12-10-2018 HW35_06720 ed39c724b5e0ffc11a887e519f606856 312 Pfam PF01544 CorA-like Mg2+ transporter protein 22 307 9.8E-66 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 HW35_06720 ed39c724b5e0ffc11a887e519f606856 312 Gene3D G3DSA:1.20.58.340 256 312 1.3E-12 T 12-10-2018 HW35_06720 ed39c724b5e0ffc11a887e519f606856 312 SUPERFAMILY SSF143865 20 247 1.23E-56 T 12-10-2018 HW35_06720 ed39c724b5e0ffc11a887e519f606856 312 Gene3D G3DSA:1.20.58.340 133 254 4.5E-29 T 12-10-2018 HW35_03880 e91d43c0829a149dda2f31b4913cbc64 437 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 HW35_03880 e91d43c0829a149dda2f31b4913cbc64 437 SUPERFAMILY SSF51230 2 95 3.75E-28 T 12-10-2018 IPR011053 Single hybrid motif HW35_03880 e91d43c0829a149dda2f31b4913cbc64 437 Gene3D G3DSA:4.10.320.10 107 157 3.4E-16 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 HW35_03880 e91d43c0829a149dda2f31b4913cbc64 437 Pfam PF00364 Biotin-requiring enzyme 4 77 6.4E-24 T 12-10-2018 IPR000089 Biotin/lipoyl attachment HW35_03880 e91d43c0829a149dda2f31b4913cbc64 437 Gene3D G3DSA:2.40.50.100 1 102 5.4E-29 T 12-10-2018 HW35_03880 e91d43c0829a149dda2f31b4913cbc64 437 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 206 430 3.7E-83 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 HW35_03880 e91d43c0829a149dda2f31b4913cbc64 437 SUPERFAMILY SSF52777 208 429 9.34E-84 T 12-10-2018 HW35_03880 e91d43c0829a149dda2f31b4913cbc64 437 Gene3D G3DSA:3.30.559.10 190 437 1.2E-98 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 HW35_03880 e91d43c0829a149dda2f31b4913cbc64 437 SUPERFAMILY SSF47005 108 153 5.23E-12 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 HW35_03880 e91d43c0829a149dda2f31b4913cbc64 437 Pfam PF02817 e3 binding domain 115 149 2.5E-13 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 SUPERFAMILY SSF52540 267 597 1.39E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 Gene3D G3DSA:3.40.50.300 215 455 2.1E-14 T 12-10-2018 HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 Pfam PF00271 Helicase conserved C-terminal domain 488 593 9.0E-8 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 Pfam PF04851 Type III restriction enzyme, res subunit 258 421 1.5E-9 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 SUPERFAMILY SSF109604 14 153 2.79E-7 T 12-10-2018 HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 Pfam PF01966 HD domain 17 118 7.6E-7 T 12-10-2018 IPR006674 HD domain HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 274 609 1.7E-45 T 12-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 18 206 9.3E-30 T 12-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 SMART SM00487 251 471 3.9E-6 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 SMART SM00490 509 593 1.9E-7 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 Gene3D G3DSA:1.10.3210.30 1 183 1.1E-14 T 12-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily HW35_13995 5533b927d53e03944d6d1a56d60baa5f 809 Gene3D G3DSA:3.40.50.300 456 633 7.7E-16 T 12-10-2018 HW35_11160 10133fadf181f76646f85e9a850467b0 228 SMART SM00862 145 222 7.2E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_11160 10133fadf181f76646f85e9a850467b0 228 Gene3D G3DSA:3.40.50.2300 1 124 7.8E-39 T 12-10-2018 HW35_11160 10133fadf181f76646f85e9a850467b0 228 SUPERFAMILY SSF52172 1 172 1.42E-42 T 12-10-2018 IPR011006 CheY-like superfamily HW35_11160 10133fadf181f76646f85e9a850467b0 228 Pfam PF00072 Response regulator receiver domain 4 112 2.0E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_11160 10133fadf181f76646f85e9a850467b0 228 Gene3D G3DSA:1.10.10.10 125 225 1.1E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_11160 10133fadf181f76646f85e9a850467b0 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 3.2E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_11160 10133fadf181f76646f85e9a850467b0 228 SMART SM00448 2 112 4.1E-40 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Pfam PF03483 B3/4 domain 222 394 3.6E-68 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Gene3D G3DSA:3.30.56.10 4 189 1.2E-70 T 12-10-2018 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Gene3D G3DSA:3.30.56.10 411 483 6.5E-28 T 12-10-2018 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Gene3D G3DSA:3.30.70.380 711 803 7.1E-29 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 803 4.5E-279 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 SUPERFAMILY SSF46955 411 483 1.74E-21 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 SUPERFAMILY SSF54991 705 803 1.7E-30 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Pfam PF01588 Putative tRNA binding domain 46 152 2.2E-28 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 SMART SM00896 710 803 3.6E-39 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Pfam PF03484 tRNA synthetase B5 domain 414 479 4.3E-21 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 SMART SM00874 411 479 2.6E-29 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 SUPERFAMILY SSF50249 36 199 5.63E-49 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Gene3D G3DSA:3.50.40.10 204 404 6.6E-84 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 SMART SM00873 221 394 3.2E-93 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 SUPERFAMILY SSF56037 210 402 2.01E-72 T 12-10-2018 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Gene3D G3DSA:2.40.50.140 40 161 1.2E-70 T 12-10-2018 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 797 47.662 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Pfam PF03147 Ferredoxin-fold anticodon binding domain 710 803 3.1E-27 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 SUPERFAMILY SSF55681 475 696 9.94E-55 T 12-10-2018 HW35_05525 b200bfc5895c74d1cf177f75c3572678 804 Gene3D G3DSA:3.30.930.10 495 699 6.5E-64 T 12-10-2018 HW35_09200 9781af08e8023a5286fa3f50e028360f 204 Pfam PF00265 Thymidine kinase 8 187 4.5E-59 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 HW35_09200 9781af08e8023a5286fa3f50e028360f 204 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 37.848 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 HW35_09200 9781af08e8023a5286fa3f50e028360f 204 SUPERFAMILY SSF57716 142 191 4.63E-16 T 12-10-2018 HW35_09200 9781af08e8023a5286fa3f50e028360f 204 PIRSF PIRSF035805 5 201 3.8E-66 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 HW35_09200 9781af08e8023a5286fa3f50e028360f 204 Gene3D G3DSA:3.40.50.300 1 141 3.3E-60 T 12-10-2018 HW35_09200 9781af08e8023a5286fa3f50e028360f 204 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 12-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 HW35_09200 9781af08e8023a5286fa3f50e028360f 204 Gene3D G3DSA:3.30.60.20 142 193 6.3E-26 T 12-10-2018 HW35_09200 9781af08e8023a5286fa3f50e028360f 204 SUPERFAMILY SSF52540 8 142 1.02E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03845 8ed102f5f5df6d056e6f2f0331a1eff8 515 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 194 205 8.7E-5 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_03845 8ed102f5f5df6d056e6f2f0331a1eff8 515 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 147 8.7E-5 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_03845 8ed102f5f5df6d056e6f2f0331a1eff8 515 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 95 109 8.7E-5 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_03845 8ed102f5f5df6d056e6f2f0331a1eff8 515 SUPERFAMILY SSF52096 3 256 3.42E-84 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_03845 8ed102f5f5df6d056e6f2f0331a1eff8 515 SUPERFAMILY SSF52096 243 515 2.49E-91 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_03845 8ed102f5f5df6d056e6f2f0331a1eff8 515 Gene3D G3DSA:3.90.226.10 260 515 2.4E-92 T 12-10-2018 HW35_03845 8ed102f5f5df6d056e6f2f0331a1eff8 515 Pfam PF01039 Carboxyl transferase domain 28 513 4.8E-199 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 HW35_03845 8ed102f5f5df6d056e6f2f0331a1eff8 515 Gene3D G3DSA:3.90.226.10 2 258 1.2E-99 T 12-10-2018 HW35_17025 515c643c564052a628ba95bfa6731136 514 Gene3D G3DSA:3.80.30.20 213 446 3.9E-93 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HW35_17025 515c643c564052a628ba95bfa6731136 514 Pfam PF04055 Radical SAM superfamily 218 389 8.6E-35 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_17025 515c643c564052a628ba95bfa6731136 514 SUPERFAMILY SSF102114 202 436 4.45E-66 T 12-10-2018 HW35_17025 515c643c564052a628ba95bfa6731136 514 Pfam PF01938 TRAM domain 443 505 8.4E-17 T 12-10-2018 IPR002792 TRAM domain HW35_17025 515c643c564052a628ba95bfa6731136 514 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 69 506 75.375 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 HW35_17025 515c643c564052a628ba95bfa6731136 514 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 218 238 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 HW35_17025 515c643c564052a628ba95bfa6731136 514 Gene3D G3DSA:3.40.50.12160 69 204 8.4E-35 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily HW35_17025 515c643c564052a628ba95bfa6731136 514 SMART SM00729 214 432 6.1E-68 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HW35_17025 515c643c564052a628ba95bfa6731136 514 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 70 505 1.2E-210 T 12-10-2018 HW35_17025 515c643c564052a628ba95bfa6731136 514 Pfam PF00919 Uncharacterized protein family UPF0004 70 171 3.3E-29 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 HW35_17025 515c643c564052a628ba95bfa6731136 514 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 70 502 1.4E-165 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 HW35_07825 92fd76dd751a3a9c8202925b38a5ed10 436 Gene3D G3DSA:3.90.20.10 6 136 5.5E-6 T 12-10-2018 HW35_07825 92fd76dd751a3a9c8202925b38a5ed10 436 Pfam PF01551 Peptidase family M23 326 429 2.6E-29 T 12-10-2018 IPR016047 Peptidase M23 HW35_07825 92fd76dd751a3a9c8202925b38a5ed10 436 Gene3D G3DSA:2.70.70.10 296 433 9.7E-37 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_07825 92fd76dd751a3a9c8202925b38a5ed10 436 SUPERFAMILY SSF51261 217 430 2.04E-45 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_16150 c6f392ef336e710e51ad790bac0f9574 135 Pfam PF14071 Putative coat protein 12 135 2.3E-39 T 12-10-2018 IPR025953 Putative coat protein YlbD HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 Gene3D G3DSA:1.10.287.380 807 879 2.2E-23 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 Gene3D G3DSA:1.10.730.10 8 742 0.0 T 12-10-2018 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 SUPERFAMILY SSF50677 197 347 7.33E-67 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 SUPERFAMILY SSF46589 814 878 1.05E-16 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 Gene3D G3DSA:3.40.50.620 28 526 0.0 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 SUPERFAMILY SSF52374 5 575 1.52E-146 T 12-10-2018 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 564 2.0E-227 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 SUPERFAMILY SSF47323 577 829 8.41E-78 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 TIGRFAM TIGR00422 valS: valine--tRNA ligase 8 861 0.0 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 1.1E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 PRINTS PR00986 Valyl-tRNA synthetase signature 477 495 1.1E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 PRINTS PR00986 Valyl-tRNA synthetase signature 351 364 1.1E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 1.1E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 PRINTS PR00986 Valyl-tRNA synthetase signature 445 466 1.1E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 814 879 1.1E-22 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 Pfam PF08264 Anticodon-binding domain of tRNA 608 753 3.8E-44 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 Gene3D G3DSA:3.90.740.10 181 347 0.0 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HW35_05180 0e2dff92e5135a7ba8b84a421158f24e 881 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 879 16.341 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HW35_10315 2c616e060854773289c5dbfb75489683 210 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 7.9E-23 T 12-10-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like HW35_10315 2c616e060854773289c5dbfb75489683 210 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 129 2.4E-41 T 12-10-2018 IPR014242 Spore cortex biosynthesis protein, YabQ HW35_01400 637675a5f3439b45adb57c1b93a77d38 149 Pfam PF13673 Acetyltransferase (GNAT) domain 47 148 4.3E-18 T 12-10-2018 IPR000182 GNAT domain HW35_01400 637675a5f3439b45adb57c1b93a77d38 149 SUPERFAMILY SSF55729 13 145 1.64E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_01400 637675a5f3439b45adb57c1b93a77d38 149 Gene3D G3DSA:3.40.630.30 3 146 2.0E-21 T 12-10-2018 HW35_03240 3fd4528cf20e675028acad2bfc073f07 235 SUPERFAMILY SSF102588 6 227 5.23E-58 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 HW35_03240 3fd4528cf20e675028acad2bfc073f07 235 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 6 226 5.1E-96 T 12-10-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 HW35_03240 3fd4528cf20e675028acad2bfc073f07 235 Gene3D G3DSA:3.40.50.10320 4 235 1.7E-87 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 HW35_03240 3fd4528cf20e675028acad2bfc073f07 235 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 125 1.7E-22 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 HW35_00490 08d84fec2934cbff8e6975cdba717af6 439 SMART SM00382 158 340 5.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_00490 08d84fec2934cbff8e6975cdba717af6 439 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 22 433 1.4E-203 T 12-10-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_00490 08d84fec2934cbff8e6975cdba717af6 439 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 12 433 4.0E-195 T 12-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_00490 08d84fec2934cbff8e6975cdba717af6 439 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 346 355 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_00490 08d84fec2934cbff8e6975cdba717af6 439 SUPERFAMILY SSF52540 93 359 2.05E-96 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_00490 08d84fec2934cbff8e6975cdba717af6 439 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 24 89 1.2E-7 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_00490 08d84fec2934cbff8e6975cdba717af6 439 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 355 6.6E-74 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_00490 08d84fec2934cbff8e6975cdba717af6 439 Gene3D G3DSA:3.40.50.12240 12 438 3.8E-156 T 12-10-2018 HW35_12135 a1311cc114a86d1758169148f99884f9 169 Gene3D G3DSA:1.10.10.10 95 169 4.8E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_12135 a1311cc114a86d1758169148f99884f9 169 Gene3D G3DSA:1.10.1740.10 2 94 8.6E-22 T 12-10-2018 HW35_12135 a1311cc114a86d1758169148f99884f9 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 165 1.9E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_12135 a1311cc114a86d1758169148f99884f9 169 SUPERFAMILY SSF88946 4 86 3.53E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_12135 a1311cc114a86d1758169148f99884f9 169 Pfam PF04542 Sigma-70 region 2 9 76 1.7E-15 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_12135 a1311cc114a86d1758169148f99884f9 169 Pfam PF08281 Sigma-70, region 4 113 163 2.8E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_12135 a1311cc114a86d1758169148f99884f9 169 SUPERFAMILY SSF88659 100 166 3.71E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_09925 a06fd79af4851b5c189de0752211059b 253 PIRSF PIRSF009320 2 78 2.8E-15 T 12-10-2018 HW35_09925 a06fd79af4851b5c189de0752211059b 253 PIRSF PIRSF009320 90 251 1.6E-7 T 12-10-2018 HW35_09925 a06fd79af4851b5c189de0752211059b 253 Pfam PF13614 AAA domain 2 178 3.6E-73 T 12-10-2018 IPR025669 AAA domain HW35_09925 a06fd79af4851b5c189de0752211059b 253 PRINTS PR00091 Nitrogenase component II signature 31 46 8.7E-5 T 12-10-2018 HW35_09925 a06fd79af4851b5c189de0752211059b 253 PRINTS PR00091 Nitrogenase component II signature 9 22 8.7E-5 T 12-10-2018 HW35_09925 a06fd79af4851b5c189de0752211059b 253 Gene3D G3DSA:3.40.50.300 1 252 7.1E-84 T 12-10-2018 HW35_09925 a06fd79af4851b5c189de0752211059b 253 SUPERFAMILY SSF52540 3 251 4.32E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16810 b0c2e90dd9de2bd83bea0233e53bf02b 156 Gene3D G3DSA:3.30.300.70 1 80 6.4E-32 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily HW35_16810 b0c2e90dd9de2bd83bea0233e53bf02b 156 Pfam PF02576 RimP N-terminal domain 12 83 3.1E-30 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal HW35_16810 b0c2e90dd9de2bd83bea0233e53bf02b 156 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 155 26.165 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 HW35_16810 b0c2e90dd9de2bd83bea0233e53bf02b 156 Gene3D G3DSA:2.30.30.180 87 153 6.6E-26 T 12-10-2018 HW35_16810 b0c2e90dd9de2bd83bea0233e53bf02b 156 SUPERFAMILY SSF75420 2 83 2.62E-28 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily HW35_16810 b0c2e90dd9de2bd83bea0233e53bf02b 156 SUPERFAMILY SSF74942 84 155 8.76E-22 T 12-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily HW35_16810 b0c2e90dd9de2bd83bea0233e53bf02b 156 Pfam PF17384 RimP C-terminal SH3 domain 86 155 9.2E-23 T 12-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal HW35_16980 f753c7e50b1645f5eb8e12a0a5d6b552 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HW35_16980 f753c7e50b1645f5eb8e12a0a5d6b552 192 Gene3D G3DSA:1.20.120.1760 3 184 1.0E-9 T 12-10-2018 HW35_16980 f753c7e50b1645f5eb8e12a0a5d6b552 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 190 1.0E-63 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 HW35_16980 f753c7e50b1645f5eb8e12a0a5d6b552 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 2.8E-17 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HW35_16980 f753c7e50b1645f5eb8e12a0a5d6b552 192 PIRSF PIRSF000847 1 192 1.5E-52 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 Gene3D G3DSA:2.30.130.40 4 114 2.8E-30 T 12-10-2018 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 SUPERFAMILY SSF52540 310 586 8.69E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 568 770 1.3E-100 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 Gene3D G3DSA:3.40.50.300 311 489 2.9E-70 T 12-10-2018 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 Gene3D G3DSA:1.10.8.60 490 582 7.3E-34 T 12-10-2018 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 8 197 2.2E-41 T 12-10-2018 IPR003111 Lon, substrate-binding domain HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 593 609 7.9E-54 T 12-10-2018 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 701 720 7.9E-54 T 12-10-2018 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 354 373 7.9E-54 T 12-10-2018 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 671 690 7.9E-54 T 12-10-2018 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 724 742 7.9E-54 T 12-10-2018 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 SUPERFAMILY SSF54211 593 768 2.24E-56 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 674 682 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 Gene3D G3DSA:3.30.230.10 591 775 1.2E-86 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 Hamap MF_01973 Lon protease [lon]. 9 770 73.386 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 350 487 7.8E-24 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 SUPERFAMILY SSF88697 8 198 1.24E-46 T 12-10-2018 IPR015947 PUA-like superfamily HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 Gene3D G3DSA:1.20.58.1480 118 243 6.2E-43 T 12-10-2018 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 TIGRFAM TIGR00763 lon: endopeptidase La 10 769 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 SMART SM00464 8 200 3.6E-69 T 12-10-2018 IPR003111 Lon, substrate-binding domain HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 SMART SM00382 346 494 1.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_05255 4797c17484acd2dfd2debf81fea303ba 775 PIRSF PIRSF001174 1 773 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 426 5.8E-148 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 Pfam PF00344 SecY translocase 68 414 1.3E-115 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 2.0E-101 T 12-10-2018 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 2.0E-101 T 12-10-2018 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 2.0E-101 T 12-10-2018 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 2.0E-101 T 12-10-2018 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 399 417 2.0E-101 T 12-10-2018 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.0E-101 T 12-10-2018 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 2.0E-101 T 12-10-2018 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 2.0E-101 T 12-10-2018 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 2.0E-101 T 12-10-2018 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 PIRSF PIRSF004557 1 431 1.7E-128 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 Gene3D G3DSA:1.10.3370.10 1 426 7.6E-159 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 430 29.287 T 12-10-2018 IPR026593 Protein translocase subunit SecY HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HW35_10815 889a43b7960e4290c4a743e09e85dc8a 431 SUPERFAMILY SSF103491 1 421 2.22E-129 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HW35_16445 9eba4720a25f48b0a8267061190c1ae3 163 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HW35_16445 9eba4720a25f48b0a8267061190c1ae3 163 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 150 16.693 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HW35_16445 9eba4720a25f48b0a8267061190c1ae3 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 2.1E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HW35_16445 9eba4720a25f48b0a8267061190c1ae3 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 2.1E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HW35_16445 9eba4720a25f48b0a8267061190c1ae3 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 2.1E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HW35_16445 9eba4720a25f48b0a8267061190c1ae3 163 Pfam PF01252 Signal peptidase (SPase) II 7 144 1.5E-39 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HW35_16445 9eba4720a25f48b0a8267061190c1ae3 163 TIGRFAM TIGR00077 lspA: signal peptidase II 2 151 1.9E-46 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HW35_16285 24991d647583d615ec1a5ebfbcb2fb75 310 SUPERFAMILY SSF53335 4 310 4.96E-48 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_16285 24991d647583d615ec1a5ebfbcb2fb75 310 Pfam PF01795 MraW methylase family 2 310 8.7E-136 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 HW35_16285 24991d647583d615ec1a5ebfbcb2fb75 310 Gene3D G3DSA:1.10.150.170 111 215 2.2E-107 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 HW35_16285 24991d647583d615ec1a5ebfbcb2fb75 310 SUPERFAMILY SSF81799 113 214 2.62E-36 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 HW35_16285 24991d647583d615ec1a5ebfbcb2fb75 310 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 39.827 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 HW35_16285 24991d647583d615ec1a5ebfbcb2fb75 310 Gene3D G3DSA:3.40.50.150 4 308 2.2E-107 T 12-10-2018 HW35_16285 24991d647583d615ec1a5ebfbcb2fb75 310 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 309 4.7E-130 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 HW35_16285 24991d647583d615ec1a5ebfbcb2fb75 310 PIRSF PIRSF004486 1 310 9.5E-111 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 HW35_08140 8be928455fbc8639be095528a9b238e9 690 Pfam PF01568 Molydopterin dinucleotide binding domain 566 670 9.2E-18 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 HW35_08140 8be928455fbc8639be095528a9b238e9 690 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 419 436 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 HW35_08140 8be928455fbc8639be095528a9b238e9 690 Gene3D G3DSA:2.20.25.90 4 69 3.9E-16 T 12-10-2018 HW35_08140 8be928455fbc8639be095528a9b238e9 690 Gene3D G3DSA:2.40.40.20 546 688 2.5E-26 T 12-10-2018 HW35_08140 8be928455fbc8639be095528a9b238e9 690 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 13 63 1.5E-16 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_08140 8be928455fbc8639be095528a9b238e9 690 Pfam PF00384 Molybdopterin oxidoreductase 67 473 3.7E-61 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_08140 8be928455fbc8639be095528a9b238e9 690 Gene3D G3DSA:3.40.228.10 145 544 1.3E-154 T 12-10-2018 HW35_08140 8be928455fbc8639be095528a9b238e9 690 Gene3D G3DSA:3.40.50.740 78 479 1.3E-154 T 12-10-2018 HW35_08140 8be928455fbc8639be095528a9b238e9 690 SMART SM00926 9 64 2.9E-19 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_08140 8be928455fbc8639be095528a9b238e9 690 SUPERFAMILY SSF53706 13 568 5.76E-168 T 12-10-2018 HW35_08140 8be928455fbc8639be095528a9b238e9 690 Gene3D G3DSA:3.30.2070.10 434 522 1.3E-154 T 12-10-2018 HW35_08140 8be928455fbc8639be095528a9b238e9 690 SUPERFAMILY SSF50692 528 682 9.95E-32 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily HW35_17715 07a9f52f2ebe2dac8a77f4db69298bd3 391 Gene3D G3DSA:3.90.230.10 155 387 1.5E-47 T 12-10-2018 HW35_17715 07a9f52f2ebe2dac8a77f4db69298bd3 391 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 156 2.5E-22 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 HW35_17715 07a9f52f2ebe2dac8a77f4db69298bd3 391 Pfam PF00557 Metallopeptidase family M24 164 372 5.9E-35 T 12-10-2018 IPR000994 Peptidase M24 HW35_17715 07a9f52f2ebe2dac8a77f4db69298bd3 391 SUPERFAMILY SSF55920 156 389 6.54E-59 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like HW35_17715 07a9f52f2ebe2dac8a77f4db69298bd3 391 SUPERFAMILY SSF53092 1 154 9.07E-39 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HW35_17715 07a9f52f2ebe2dac8a77f4db69298bd3 391 Gene3D G3DSA:3.40.350.10 1 154 2.3E-37 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HW35_05175 cee5996d6dd5b39f02e4b104205f4c44 440 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 425 3.9E-130 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 HW35_05175 cee5996d6dd5b39f02e4b104205f4c44 440 Gene3D G3DSA:3.40.1190.10 3 300 3.1E-99 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HW35_05175 cee5996d6dd5b39f02e4b104205f4c44 440 Pfam PF02875 Mur ligase family, glutamate ligase domain 299 377 6.1E-9 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 HW35_05175 cee5996d6dd5b39f02e4b104205f4c44 440 SUPERFAMILY SSF53244 299 426 4.58E-25 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HW35_05175 cee5996d6dd5b39f02e4b104205f4c44 440 SUPERFAMILY SSF53623 3 299 3.56E-94 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HW35_05175 cee5996d6dd5b39f02e4b104205f4c44 440 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 HW35_05175 cee5996d6dd5b39f02e4b104205f4c44 440 PIRSF PIRSF001563 1 435 8.4E-153 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 HW35_05175 cee5996d6dd5b39f02e4b104205f4c44 440 Pfam PF08245 Mur ligase middle domain 46 274 1.0E-13 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 HW35_05175 cee5996d6dd5b39f02e4b104205f4c44 440 Gene3D G3DSA:3.90.190.20 301 432 1.1E-30 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HW35_12385 3301f2f897549e68866580a4416a804b 484 Pfam PF12229 Putative peptidoglycan binding domain 225 331 8.4E-8 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain HW35_12385 3301f2f897549e68866580a4416a804b 484 SUPERFAMILY SSF141523 356 484 1.05E-29 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like HW35_12385 3301f2f897549e68866580a4416a804b 484 Gene3D G3DSA:1.10.269.20 223 342 5.9E-17 T 12-10-2018 IPR038054 L,D-transpeptidase central domain-like superfamily HW35_12385 3301f2f897549e68866580a4416a804b 484 Gene3D G3DSA:2.40.440.10 358 484 6.6E-37 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like HW35_12385 3301f2f897549e68866580a4416a804b 484 SUPERFAMILY SSF143985 224 341 1.83E-26 T 12-10-2018 IPR038054 L,D-transpeptidase central domain-like superfamily HW35_12385 3301f2f897549e68866580a4416a804b 484 Pfam PF03734 L,D-transpeptidase catalytic domain 359 483 1.9E-14 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 Gene3D G3DSA:3.30.420.340 365 523 1.5E-61 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 28.591 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 Gene3D G3DSA:1.10.150.20 527 589 1.5E-19 T 12-10-2018 HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 Gene3D G3DSA:3.40.1440.10 1 99 7.4E-38 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 SMART SM00465 15 95 5.7E-24 T 12-10-2018 IPR000305 GIY-YIG endonuclease HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 376 523 1.6E-55 T 12-10-2018 IPR001162 UvrC family homology region HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 6 570 5.3E-214 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 SUPERFAMILY SSF47781 501 589 1.78E-20 T 12-10-2018 IPR010994 RuvA domain 2-like HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 SUPERFAMILY SSF82771 14 97 9.02E-22 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 SUPERFAMILY SSF46600 182 235 1.01E-13 T 12-10-2018 IPR036876 UVR domain superfamily HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 Pfam PF02151 UvrB/uvrC motif 197 230 4.8E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 HW35_05440 bc70c65bb22f6f681997c27b4a0849f0 591 Pfam PF01541 GIY-YIG catalytic domain 16 90 2.3E-10 T 12-10-2018 IPR000305 GIY-YIG endonuclease HW35_10350 aef4453e99b311b7b78795138775f54d 461 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 384 430 1.4E-21 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HW35_10350 aef4453e99b311b7b78795138775f54d 461 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 209 1.1E-55 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HW35_10350 aef4453e99b311b7b78795138775f54d 461 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 6 320 24.144 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HW35_10350 aef4453e99b311b7b78795138775f54d 461 Pfam PF01171 PP-loop family 21 206 6.9E-56 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 HW35_10350 aef4453e99b311b7b78795138775f54d 461 SUPERFAMILY SSF56037 340 445 1.44E-19 T 12-10-2018 HW35_10350 aef4453e99b311b7b78795138775f54d 461 Pfam PF11734 TilS substrate C-terminal domain 386 444 5.1E-16 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HW35_10350 aef4453e99b311b7b78795138775f54d 461 Gene3D G3DSA:3.40.50.620 10 239 3.0E-67 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_10350 aef4453e99b311b7b78795138775f54d 461 Gene3D G3DSA:1.20.59.30 247 331 2.7E-27 T 12-10-2018 HW35_10350 aef4453e99b311b7b78795138775f54d 461 SMART SM00977 384 457 4.5E-26 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HW35_10350 aef4453e99b311b7b78795138775f54d 461 SUPERFAMILY SSF52402 15 239 1.65E-55 T 12-10-2018 HW35_10350 aef4453e99b311b7b78795138775f54d 461 SUPERFAMILY SSF82829 218 323 1.49E-12 T 12-10-2018 HW35_10350 aef4453e99b311b7b78795138775f54d 461 Pfam PF09179 TilS substrate binding domain 259 323 2.4E-4 T 12-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HW35_06665 f918c88be593c3968d4fbf788054690d 620 SUPERFAMILY SSF82282 1 363 1.57E-101 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 HW35_06665 f918c88be593c3968d4fbf788054690d 620 Pfam PF02574 Homocysteine S-methyltransferase 12 280 1.6E-56 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 HW35_06665 f918c88be593c3968d4fbf788054690d 620 Pfam PF02219 Methylenetetrahydrofolate reductase 318 578 2.0E-28 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HW35_06665 f918c88be593c3968d4fbf788054690d 620 Gene3D G3DSA:3.20.20.220 313 594 6.4E-52 T 12-10-2018 HW35_06665 f918c88be593c3968d4fbf788054690d 620 SUPERFAMILY SSF51730 318 599 2.94E-68 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like HW35_06665 f918c88be593c3968d4fbf788054690d 620 Gene3D G3DSA:3.20.20.330 2 293 3.9E-88 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 HW35_06195 84beb1e535e6c430db9679b9f64b31d2 187 PIRSF PIRSF000239 1 187 1.8E-50 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HW35_06195 84beb1e535e6c430db9679b9f64b31d2 187 Gene3D G3DSA:3.40.30.10 1 186 2.6E-58 T 12-10-2018 HW35_06195 84beb1e535e6c430db9679b9f64b31d2 187 SUPERFAMILY SSF52833 1 187 1.03E-54 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_06195 84beb1e535e6c430db9679b9f64b31d2 187 Pfam PF00578 AhpC/TSA family 4 133 3.3E-33 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HW35_06195 84beb1e535e6c430db9679b9f64b31d2 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 1.6E-4 T 12-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HW35_06195 84beb1e535e6c430db9679b9f64b31d2 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 1.1E-103 T 12-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 235 1441 0.0 T 12-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Gene3D G3DSA:1.10.100.20 999 1046 2.4E-61 T 12-10-2018 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 418 639 1.3E-66 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Pfam PF14579 Helix-hairpin-helix motif 1358 1434 3.3E-9 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 SMART SM00481 340 407 9.9E-26 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Gene3D G3DSA:1.10.150.870 1291 1427 2.9E-55 T 12-10-2018 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Gene3D G3DSA:3.30.420.10 418 559 5.5E-46 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Gene3D G3DSA:1.10.150.700 1100 1188 8.7E-37 T 12-10-2018 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Gene3D G3DSA:1.10.150.700 1238 1290 5.4E-14 T 12-10-2018 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Pfam PF02811 PHP domain 341 698 1.0E-53 T 12-10-2018 IPR004013 PHP domain GO:0003824 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 SMART SM00479 425 591 1.1E-57 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Gene3D G3DSA:3.20.20.140 340 406 5.5E-10 T 12-10-2018 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Pfam PF14480 DNA polymerase III polC-type N-terminus I 11 83 4.4E-21 T 12-10-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 SUPERFAMILY SSF53098 425 881 1.82E-111 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1441 461.138 T 12-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 SUPERFAMILY SSF50249 240 323 4.0E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Gene3D G3DSA:3.30.1900.20 977 1099 2.4E-61 T 12-10-2018 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Gene3D G3DSA:2.40.50.140 224 325 6.6E-33 T 12-10-2018 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Pfam PF11490 DNA polymerase III polC-type N-terminus II 97 207 3.8E-24 T 12-10-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Pfam PF00929 Exonuclease 427 581 1.2E-43 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 829 1248 1.1E-98 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Pfam PF01336 OB-fold nucleic acid binding domain 243 308 8.9E-7 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HW35_16805 890692e1efc9f5f8c3bb3ab04804ec0a 1441 Gene3D G3DSA:3.20.20.140 560 809 4.3E-54 T 12-10-2018 HW35_08105 ea6e07476aa294fc021db0457f998095 473 ProSitePatterns PS00018 EF-hand calcium-binding domain. 444 456 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site HW35_08105 ea6e07476aa294fc021db0457f998095 473 Pfam PF13365 Trypsin-like peptidase domain 86 276 3.0E-23 T 12-10-2018 HW35_08105 ea6e07476aa294fc021db0457f998095 473 SUPERFAMILY SSF50494 32 308 1.29E-36 T 12-10-2018 IPR009003 Peptidase S1, PA clan HW35_08105 ea6e07476aa294fc021db0457f998095 473 Gene3D G3DSA:2.40.10.10 196 313 1.9E-22 T 12-10-2018 HW35_08105 ea6e07476aa294fc021db0457f998095 473 PRINTS PR00834 HtrA/DegQ protease family signature 95 107 6.7E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HW35_08105 ea6e07476aa294fc021db0457f998095 473 PRINTS PR00834 HtrA/DegQ protease family signature 269 286 6.7E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HW35_08105 ea6e07476aa294fc021db0457f998095 473 PRINTS PR00834 HtrA/DegQ protease family signature 247 264 6.7E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HW35_13945 4aab1ffe5d0708dbff0623ca9c624435 308 SUPERFAMILY SSF52172 2 140 2.99E-25 T 12-10-2018 IPR011006 CheY-like superfamily HW35_13945 4aab1ffe5d0708dbff0623ca9c624435 308 Pfam PF08664 YcbB domain 160 298 1.6E-49 T 12-10-2018 IPR013972 YcbB domain HW35_13945 4aab1ffe5d0708dbff0623ca9c624435 308 SMART SM00448 1 114 3.6E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_13945 4aab1ffe5d0708dbff0623ca9c624435 308 Pfam PF00072 Response regulator receiver domain 4 114 3.7E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_13945 4aab1ffe5d0708dbff0623ca9c624435 308 Gene3D G3DSA:3.40.50.12740 1 178 1.4E-23 T 12-10-2018 HW35_06000 c79e6dfa24e8ba9eb26e81eee7184028 711 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 95 687 1.9E-243 T 12-10-2018 IPR011840 Pullulanase, type I HW35_06000 c79e6dfa24e8ba9eb26e81eee7184028 711 SMART SM00642 222 617 1.3E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_06000 c79e6dfa24e8ba9eb26e81eee7184028 711 SUPERFAMILY SSF81296 100 202 3.32E-16 T 12-10-2018 IPR014756 Immunoglobulin E-set HW35_06000 c79e6dfa24e8ba9eb26e81eee7184028 711 Gene3D G3DSA:2.60.40.2320 1 97 8.1E-33 T 12-10-2018 HW35_06000 c79e6dfa24e8ba9eb26e81eee7184028 711 Pfam PF00128 Alpha amylase, catalytic domain 260 344 2.5E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_06000 c79e6dfa24e8ba9eb26e81eee7184028 711 Pfam PF00128 Alpha amylase, catalytic domain 378 576 1.8E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_06000 c79e6dfa24e8ba9eb26e81eee7184028 711 Gene3D G3DSA:3.20.20.80 204 626 1.1E-179 T 12-10-2018 HW35_06000 c79e6dfa24e8ba9eb26e81eee7184028 711 Gene3D G3DSA:2.60.40.10 98 203 1.7E-27 T 12-10-2018 IPR013783 Immunoglobulin-like fold HW35_06000 c79e6dfa24e8ba9eb26e81eee7184028 711 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 107 183 3.2E-12 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 HW35_06000 c79e6dfa24e8ba9eb26e81eee7184028 711 SUPERFAMILY SSF51445 198 624 4.85E-126 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_12095 09dc139fba37fbfc74310757b413da76 529 SMART SM00448 2 116 1.5E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_12095 09dc139fba37fbfc74310757b413da76 529 SUPERFAMILY SSF46689 476 525 9.86E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_12095 09dc139fba37fbfc74310757b413da76 529 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 492 507 1.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HW35_12095 09dc139fba37fbfc74310757b413da76 529 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 507 523 1.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HW35_12095 09dc139fba37fbfc74310757b413da76 529 Gene3D G3DSA:1.10.10.60 474 526 5.6E-20 T 12-10-2018 HW35_12095 09dc139fba37fbfc74310757b413da76 529 SUPERFAMILY SSF52172 1 158 6.83E-34 T 12-10-2018 IPR011006 CheY-like superfamily HW35_12095 09dc139fba37fbfc74310757b413da76 529 Gene3D G3DSA:3.40.50.12740 2 176 2.6E-36 T 12-10-2018 HW35_12095 09dc139fba37fbfc74310757b413da76 529 Gene3D G3DSA:1.10.10.60 423 473 1.8E-16 T 12-10-2018 HW35_12095 09dc139fba37fbfc74310757b413da76 529 SMART SM00342 440 523 2.7E-33 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HW35_12095 09dc139fba37fbfc74310757b413da76 529 Pfam PF00072 Response regulator receiver domain 4 116 1.4E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_12095 09dc139fba37fbfc74310757b413da76 529 SUPERFAMILY SSF46689 425 474 4.36E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_12095 09dc139fba37fbfc74310757b413da76 529 Pfam PF12833 Helix-turn-helix domain 447 524 6.9E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HW35_12095 09dc139fba37fbfc74310757b413da76 529 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 477 519 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 HW35_15525 3107c22f5a28ecfe0e5ad7124ef25571 271 PIRSF PIRSF004846 1 271 1.1E-91 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 HW35_15525 3107c22f5a28ecfe0e5ad7124ef25571 271 Pfam PF13531 Bacterial extracellular solute-binding protein 46 267 1.5E-51 T 12-10-2018 HW35_15525 3107c22f5a28ecfe0e5ad7124ef25571 271 Gene3D G3DSA:3.40.190.10 48 267 6.5E-79 T 12-10-2018 HW35_15525 3107c22f5a28ecfe0e5ad7124ef25571 271 Gene3D G3DSA:3.40.190.10 125 230 6.5E-79 T 12-10-2018 HW35_15525 3107c22f5a28ecfe0e5ad7124ef25571 271 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 51 266 7.6E-70 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 HW35_15525 3107c22f5a28ecfe0e5ad7124ef25571 271 SUPERFAMILY SSF53850 45 267 5.32E-69 T 12-10-2018 HW35_09330 29ca8a136310ac915cee59c186b93dec 686 Gene3D G3DSA:1.10.3810.10 64 259 2.5E-77 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_09330 29ca8a136310ac915cee59c186b93dec 686 SUPERFAMILY SSF56601 219 662 8.16E-115 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_09330 29ca8a136310ac915cee59c186b93dec 686 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 73 608 3.4E-182 T 12-10-2018 HW35_09330 29ca8a136310ac915cee59c186b93dec 686 Pfam PF00912 Transglycosylase 62 237 2.3E-65 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_09330 29ca8a136310ac915cee59c186b93dec 686 Pfam PF00905 Penicillin binding protein transpeptidase domain 329 603 6.0E-34 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HW35_09330 29ca8a136310ac915cee59c186b93dec 686 SUPERFAMILY SSF53955 50 261 1.38E-76 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily HW35_09330 29ca8a136310ac915cee59c186b93dec 686 Gene3D G3DSA:3.40.710.10 260 667 7.8E-114 T 12-10-2018 HW35_03230 5193707b4fe9df6e7e0ab153e2434e2e 399 Gene3D G3DSA:3.30.460.10 2 144 2.0E-54 T 12-10-2018 HW35_03230 5193707b4fe9df6e7e0ab153e2434e2e 399 Gene3D G3DSA:1.10.246.80 341 399 1.0E-22 T 12-10-2018 HW35_03230 5193707b4fe9df6e7e0ab153e2434e2e 399 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 170 228 1.4E-14 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 HW35_03230 5193707b4fe9df6e7e0ab153e2434e2e 399 Pfam PF01743 Poly A polymerase head domain 22 141 3.8E-37 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 HW35_03230 5193707b4fe9df6e7e0ab153e2434e2e 399 Hamap MF_01263 CCA-adding enzyme [cca]. 2 397 40.551 T 12-10-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 HW35_03230 5193707b4fe9df6e7e0ab153e2434e2e 399 SUPERFAMILY SSF81301 7 139 1.63E-42 T 12-10-2018 HW35_03230 5193707b4fe9df6e7e0ab153e2434e2e 399 Gene3D G3DSA:1.20.58.560 243 340 2.9E-16 T 12-10-2018 HW35_03230 5193707b4fe9df6e7e0ab153e2434e2e 399 Gene3D G3DSA:1.10.110.30 145 240 6.1E-29 T 12-10-2018 HW35_03230 5193707b4fe9df6e7e0ab153e2434e2e 399 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 248 392 1.7E-35 T 12-10-2018 IPR032810 CCA-adding enzyme, C-terminal HW35_03230 5193707b4fe9df6e7e0ab153e2434e2e 399 SUPERFAMILY SSF81891 140 396 7.19E-45 T 12-10-2018 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 SUPERFAMILY SSF50249 5 146 1.91E-44 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_10415 87ec4964ce71388b7533d09f33c07840 494 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 493 5.5E-228 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 Gene3D G3DSA:3.30.930.10 147 491 2.3E-138 T 12-10-2018 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 376 392 3.7E-40 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 206 222 3.7E-40 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 253 270 3.7E-40 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 190 200 3.7E-40 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 235 248 3.7E-40 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 Pfam PF01336 OB-fold nucleic acid binding domain 60 134 6.2E-15 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 Gene3D G3DSA:2.40.50.140 6 146 9.1E-46 T 12-10-2018 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 Pfam PF00152 tRNA synthetases class II (D, K and N) 154 491 4.7E-84 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 12 494 46.47 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 PIRSF PIRSF039101 2 494 1.2E-206 T 12-10-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_10415 87ec4964ce71388b7533d09f33c07840 494 SUPERFAMILY SSF55681 153 492 1.57E-124 T 12-10-2018 HW35_11715 30cd631a74c65b789387160653fccf41 469 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 454 2.0E-167 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 HW35_11715 30cd631a74c65b789387160653fccf41 469 SUPERFAMILY SSF53271 246 463 2.88E-75 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_11715 30cd631a74c65b789387160653fccf41 469 PIRSF PIRSF000485 8 468 6.9E-187 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 HW35_11715 30cd631a74c65b789387160653fccf41 469 SUPERFAMILY SSF56235 12 234 3.35E-69 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HW35_11715 30cd631a74c65b789387160653fccf41 469 Pfam PF13522 Glutamine amidotransferase domain 70 204 9.9E-23 T 12-10-2018 HW35_11715 30cd631a74c65b789387160653fccf41 469 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 453 47.474 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 HW35_11715 30cd631a74c65b789387160653fccf41 469 Gene3D G3DSA:3.60.20.10 12 455 7.8E-170 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HW35_11715 30cd631a74c65b789387160653fccf41 469 Pfam PF00156 Phosphoribosyl transferase domain 278 383 1.5E-9 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HW35_11715 30cd631a74c65b789387160653fccf41 469 Gene3D G3DSA:3.40.50.2020 270 434 7.8E-170 T 12-10-2018 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 444 458 - T 12-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 SUPERFAMILY SSF51445 325 612 5.39E-85 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 SUPERFAMILY SSF49303 615 711 1.01E-18 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 SUPERFAMILY SSF49785 8 218 2.27E-64 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 SUPERFAMILY SSF49303 220 322 2.48E-19 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 Pfam PF02929 Beta galactosidase small chain 737 1004 3.6E-69 T 12-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 Gene3D G3DSA:2.60.40.10 220 322 4.0E-20 T 12-10-2018 IPR013783 Immunoglobulin-like fold HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 PRINTS PR00132 Glycosyl hydrolase family 2 signature 364 382 1.3E-36 T 12-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 PRINTS PR00132 Glycosyl hydrolase family 2 signature 146 161 1.3E-36 T 12-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 PRINTS PR00132 Glycosyl hydrolase family 2 signature 333 347 1.3E-36 T 12-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 PRINTS PR00132 Glycosyl hydrolase family 2 signature 444 459 1.3E-36 T 12-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 PRINTS PR00132 Glycosyl hydrolase family 2 signature 519 534 1.3E-36 T 12-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 Gene3D G3DSA:2.70.98.10 723 1006 6.5E-76 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 374 399 - T 12-10-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 SUPERFAMILY SSF74650 720 1005 5.02E-82 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 Gene3D G3DSA:3.20.20.80 325 610 8.5E-98 T 12-10-2018 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 SMART SM01038 734 1005 3.8E-105 T 12-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 Gene3D G3DSA:2.60.120.260 4 219 6.7E-81 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 325 615 8.9E-126 T 12-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 47 218 9.8E-35 T 12-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 Pfam PF00703 Glycosyl hydrolases family 2 220 322 7.9E-14 T 12-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 Gene3D G3DSA:2.60.40.10 612 713 1.4E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold HW35_12380 3f9359ca4ca26d3da85868fd13022387 1007 Pfam PF16353 Domain of unknown function(DUF4981) 623 709 3.3E-17 T 12-10-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HW35_12295 ec608c3edf07da26139e53e74c3b4b19 176 Gene3D G3DSA:3.90.79.10 6 175 2.1E-47 T 12-10-2018 HW35_12295 ec608c3edf07da26139e53e74c3b4b19 176 PRINTS PR00502 NUDIX hydrolase family signature 84 99 4.9E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HW35_12295 ec608c3edf07da26139e53e74c3b4b19 176 PRINTS PR00502 NUDIX hydrolase family signature 68 82 4.9E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HW35_12295 ec608c3edf07da26139e53e74c3b4b19 176 SUPERFAMILY SSF55811 15 172 5.01E-39 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 HW35_12295 ec608c3edf07da26139e53e74c3b4b19 176 Pfam PF00293 NUDIX domain 40 150 3.3E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 SUPERFAMILY SSF101801 247 321 9.42E-15 T 12-10-2018 IPR036429 SpoA-like superfamily HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 1.4E-24 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 PRINTS PR00955 Flagellar motor switch protein FliM signature 88 104 1.4E-24 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 PRINTS PR00955 Flagellar motor switch protein FliM signature 113 132 1.4E-24 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 PRINTS PR00955 Flagellar motor switch protein FliM signature 209 227 1.4E-24 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 Gene3D G3DSA:3.40.1550.10 45 234 3.9E-54 T 12-10-2018 IPR028976 CheC-like superfamily HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 Pfam PF02154 Flagellar motor switch protein FliM 37 227 1.4E-62 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 Gene3D G3DSA:2.30.330.10 236 323 3.5E-6 T 12-10-2018 IPR036429 SpoA-like superfamily HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 SUPERFAMILY SSF103039 45 228 6.28E-22 T 12-10-2018 IPR028976 CheC-like superfamily HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 317 1.0E-95 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 250 317 6.9E-17 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) HW35_00230 da12c67c52a27c4f82a7cb8f480b7c84 324 PIRSF PIRSF002888 1 324 2.5E-100 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HW35_13610 b73b38ed9856993d5a56093341df3fba 349 Pfam PF07730 Histidine kinase 145 213 2.0E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HW35_13610 b73b38ed9856993d5a56093341df3fba 349 SMART SM00387 249 342 1.3E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_13610 b73b38ed9856993d5a56093341df3fba 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 249 339 1.3E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_13610 b73b38ed9856993d5a56093341df3fba 349 PIRSF PIRSF037431 2 347 2.8E-125 T 12-10-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 HW35_13610 b73b38ed9856993d5a56093341df3fba 349 Gene3D G3DSA:3.30.565.10 211 344 6.4E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_13610 b73b38ed9856993d5a56093341df3fba 349 SUPERFAMILY SSF55874 220 339 2.75E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 Gene3D G3DSA:1.10.460.10 159 565 7.4E-140 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 SUPERFAMILY SSF56712 1 595 6.28E-180 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 680 1.7E-208 T 12-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 296 311 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 SMART SM00493 2 125 2.2E-15 T 12-10-2018 IPR006171 TOPRIM domain HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 SMART SM00436 125 215 4.7E-39 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 Gene3D G3DSA:2.70.20.10 209 468 7.4E-140 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 Pfam PF01131 DNA topoisomerase 152 556 3.2E-133 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 SMART SM00437 259 521 2.2E-76 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 3.7E-28 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 484 498 3.7E-28 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 384 400 3.7E-28 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 3.7E-28 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 302 311 3.7E-28 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 Gene3D G3DSA:1.10.290.10 268 398 7.4E-140 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 Pfam PF01751 Toprim domain 4 132 9.0E-14 T 12-10-2018 IPR006171 TOPRIM domain HW35_13650 7bfa38db7493efa5456d592cb3c9cc37 696 Gene3D G3DSA:3.40.50.140 2 153 6.6E-53 T 12-10-2018 HW35_07600 d842ca0e4c1505b11a1f7971b46ade25 328 Pfam PF01933 Uncharacterised protein family UPF0052 9 295 5.8E-110 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 HW35_07600 d842ca0e4c1505b11a1f7971b46ade25 328 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 318 1.4E-128 T 12-10-2018 IPR010119 Gluconeogenesis factor HW35_07600 d842ca0e4c1505b11a1f7971b46ade25 328 Hamap MF_00973 Gluconeogenesis factor. 5 320 36.938 T 12-10-2018 IPR010119 Gluconeogenesis factor HW35_07600 d842ca0e4c1505b11a1f7971b46ade25 328 SUPERFAMILY SSF142338 6 315 6.02E-109 T 12-10-2018 HW35_07600 d842ca0e4c1505b11a1f7971b46ade25 328 Gene3D G3DSA:3.40.50.12300 5 324 1.0E-132 T 12-10-2018 IPR038136 Gluconeogenesis factor superfamily HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 PRINTS PR00415 Aconitase family signature 147 160 1.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 PRINTS PR00415 Aconitase family signature 501 514 1.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 PRINTS PR00415 Aconitase family signature 204 217 1.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 PRINTS PR00415 Aconitase family signature 439 450 1.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 PRINTS PR00415 Aconitase family signature 294 307 1.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 PRINTS PR00415 Aconitase family signature 280 293 1.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 PRINTS PR00415 Aconitase family signature 373 387 1.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 PRINTS PR00415 Aconitase family signature 171 179 1.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 PRINTS PR00415 Aconitase family signature 218 233 1.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 SUPERFAMILY SSF53732 5 634 2.49E-228 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 Gene3D G3DSA:3.30.499.10 374 598 2.2E-103 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 Gene3D G3DSA:3.30.499.20 6 373 1.5E-158 T 12-10-2018 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 899 0.0 T 12-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 Pfam PF00694 Aconitase C-terminal domain 700 827 1.7E-45 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 ProSitePatterns PS00450 Aconitase family signature 1. 435 451 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 Gene3D G3DSA:1.10.1440.20 599 659 7.9E-23 T 12-10-2018 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 Gene3D G3DSA:3.20.19.10 662 900 3.9E-104 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 ProSitePatterns PS01244 Aconitase family signature 2. 501 514 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 Pfam PF00330 Aconitase family (aconitate hydratase) 77 570 8.8E-175 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_00960 5294a64835077b15a7f8ba432305ab3f 901 SUPERFAMILY SSF52016 639 898 3.34E-88 T 12-10-2018 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 Pfam PF01713 Smr domain 710 785 2.0E-19 T 12-10-2018 IPR002625 Smr domain HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 Pfam PF00488 MutS domain V 331 513 2.7E-34 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 784 22.476 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 Gene3D G3DSA:3.40.50.300 293 641 5.2E-84 T 12-10-2018 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 SMART SM00534 328 513 2.1E-75 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 SMART SM00533 9 315 2.1E-34 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 Gene3D G3DSA:3.30.1370.110 699 785 2.0E-23 T 12-10-2018 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 SUPERFAMILY SSF48334 17 286 2.09E-30 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 Gene3D G3DSA:1.10.1420.10 65 281 3.2E-9 T 12-10-2018 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 PIRSF PIRSF005814 1 785 2.5E-275 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 784 8.7E-277 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 SMART SM00463 707 785 8.9E-24 T 12-10-2018 IPR002625 Smr domain HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 SUPERFAMILY SSF52540 292 515 2.66E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 SUPERFAMILY SSF160443 708 784 1.57E-9 T 12-10-2018 IPR036063 Smr domain superfamily HW35_05485 4a5d28e5801a058d72e65e0933b63544 785 Gene3D G3DSA:1.10.1420.10 134 259 3.2E-9 T 12-10-2018 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 Gene3D G3DSA:3.30.930.10 4 243 3.4E-96 T 12-10-2018 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 277 293 4.0E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 227 240 4.0E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 301 314 4.0E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 200 211 4.0E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 4.0E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 Gene3D G3DSA:3.10.310.40 766 877 1.2E-37 T 12-10-2018 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 Pfam PF01411 tRNA synthetases class II (A) 8 557 4.5E-217 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 656 699 9.2E-19 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 Pfam PF02272 DHHA1 domain 736 875 1.0E-30 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 SUPERFAMILY SSF55186 555 710 8.37E-55 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 SUPERFAMILY SSF50447 455 555 6.0E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 879 189.687 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 Gene3D G3DSA:3.30.54.20 627 680 1.4E-51 T 12-10-2018 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 SUPERFAMILY SSF101353 247 443 8.76E-70 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 858 0.0 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 Gene3D G3DSA:2.40.30.130 463 555 1.0E-10 T 12-10-2018 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 SUPERFAMILY SSF55681 5 246 8.2E-89 T 12-10-2018 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 SMART SM00863 656 699 2.9E-21 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 HW35_04775 379d83ea39f4761aba0f7fd329e7f80c 879 Gene3D G3DSA:3.30.980.10 565 700 1.4E-51 T 12-10-2018 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 418 3.3E-182 T 12-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 SUPERFAMILY SSF52418 69 329 5.49E-93 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 SMART SM00941 345 418 4.5E-34 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 Gene3D G3DSA:1.20.970.10 1 67 2.0E-30 T 12-10-2018 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 Gene3D G3DSA:3.90.1170.30 331 420 3.0E-155 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 1.7E-23 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 PIRSF PIRSF000478 1 433 7.6E-171 T 12-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 Gene3D G3DSA:3.40.1030.10 77 330 3.0E-155 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 SUPERFAMILY SSF54680 331 433 2.22E-30 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 12-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 6.7E-27 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 1.0E-48 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_03690 8a3ae4a320a01d5629993d821502a5ea 434 SUPERFAMILY SSF47648 1 69 7.59E-24 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 Pfam PF00347 Ribosomal protein L6 90 164 1.8E-21 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 Pfam PF00347 Ribosomal protein L6 11 82 7.5E-24 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 40.182 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 PIRSF PIRSF002162 1 177 3.9E-52 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 SUPERFAMILY SSF56053 1 82 3.29E-30 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 Gene3D G3DSA:3.90.930.12 2 82 1.7E-34 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 SUPERFAMILY SSF56053 83 177 2.53E-36 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 5.1E-79 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 Gene3D G3DSA:3.90.930.12 83 178 4.5E-41 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 6.2E-35 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 6.2E-35 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HW35_10790 19053f609e86a15846ed2a6c5fdf1e02 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 6.2E-35 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 PIRSF PIRSF005536 1 728 6.5E-293 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 30 285 1.0E-95 T 12-10-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 ProSitePatterns PS00512 Alpha-galactosidase signature. 359 374 - T 12-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 Pfam PF02065 Melibiase 289 635 2.8E-163 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 Gene3D G3DSA:3.20.20.70 310 632 6.4E-135 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 Gene3D G3DSA:2.70.98.60 1 309 3.5E-122 T 12-10-2018 IPR038417 Alpha-galactosidase, N-terminal domain superfamily KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 649 725 1.7E-23 T 12-10-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 SUPERFAMILY SSF51445 325 666 1.19E-108 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 Gene3D G3DSA:2.60.40.1180 634 729 2.4E-30 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 241 256 1.3E-63 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 545 561 1.3E-63 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 520 536 1.3E-63 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 330 344 1.3E-63 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 408 430 1.3E-63 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 466 481 1.3E-63 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 292 312 1.3E-63 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_12340 2e7fcddfd33506ba20dcf3ea8295bba1 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 358 373 1.3E-63 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 HW35_03620 2a35441dee9732777a8a0b863cc89bcc 256 Hamap MF_01805 Segregation and condensation protein A [scpA]. 3 247 27.133 T 12-10-2018 IPR003768 Segregation and condensation protein A HW35_03620 2a35441dee9732777a8a0b863cc89bcc 256 Gene3D G3DSA:1.10.10.580 181 246 2.6E-5 T 12-10-2018 IPR023093 ScpA-like, C-terminal HW35_03620 2a35441dee9732777a8a0b863cc89bcc 256 Pfam PF02616 Segregation and condensation protein ScpA 20 244 6.4E-64 T 12-10-2018 IPR003768 Segregation and condensation protein A HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 SUPERFAMILY SSF51735 1 178 1.69E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 PIRSF PIRSF000149 1 334 2.8E-138 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 3.5E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 3.5E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 3.5E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 3.5E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 3.5E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 102 2.2E-37 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 Gene3D G3DSA:3.40.50.720 4 327 2.3E-151 T 12-10-2018 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 Gene3D G3DSA:3.30.360.10 151 315 2.3E-151 T 12-10-2018 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 SMART SM00846 3 152 8.1E-87 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 1.1E-69 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 SUPERFAMILY SSF55347 152 314 7.14E-73 T 12-10-2018 HW35_05610 4d50548749c6e0dfed43f7b31a21a509 343 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 1.7E-134 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_09960 edb680fc52d3a81728fadededdd3570f 115 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 107 3.0E-36 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HW35_09960 edb680fc52d3a81728fadededdd3570f 115 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 19.749 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HW35_09960 edb680fc52d3a81728fadededdd3570f 115 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 2 106 6.5E-30 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HW35_09960 edb680fc52d3a81728fadededdd3570f 115 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 12-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 HW35_09960 edb680fc52d3a81728fadededdd3570f 115 SUPERFAMILY SSF54211 1 110 1.67E-34 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_09960 edb680fc52d3a81728fadededdd3570f 115 Pfam PF00825 Ribonuclease P 1 106 1.8E-35 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HW35_09960 edb680fc52d3a81728fadededdd3570f 115 Gene3D G3DSA:3.30.230.10 1 115 7.1E-37 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_01250 3aa617ca94f471469625e94fcd693cd4 158 SUPERFAMILY SSF55961 3 143 2.2E-20 T 12-10-2018 HW35_01250 3aa617ca94f471469625e94fcd693cd4 158 Gene3D G3DSA:3.30.530.20 1 145 9.5E-23 T 12-10-2018 IPR023393 START-like domain superfamily HW35_01250 3aa617ca94f471469625e94fcd693cd4 158 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 9 143 5.4E-17 T 12-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 Gene3D G3DSA:3.10.290.10 326 417 1.7E-34 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 417 46.557 T 12-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 1.3E-88 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 416 1.5E-143 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 SUPERFAMILY SSF52374 2 323 6.14E-116 T 12-10-2018 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 SUPERFAMILY SSF55174 321 416 9.55E-24 T 12-10-2018 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 Gene3D G3DSA:1.10.240.10 223 325 8.8E-41 T 12-10-2018 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 SMART SM00363 352 413 5.5E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 Pfam PF01479 S4 domain 353 398 9.0E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 Gene3D G3DSA:3.40.50.620 1 222 8.8E-92 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 4.6E-31 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 181 203 4.6E-31 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 4.6E-31 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HW35_05895 d40cbd9041c1d4d2dceb4b333c430c74 417 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 4.6E-31 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HW35_12450 f707d79fb136261e71ccacd9b8157fbd 198 Gene3D G3DSA:3.20.20.70 4 197 7.8E-49 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_12450 f707d79fb136261e71ccacd9b8157fbd 198 Pfam PF02581 Thiamine monophosphate synthase 18 177 1.2E-37 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_12450 f707d79fb136261e71ccacd9b8157fbd 198 SUPERFAMILY SSF51391 10 190 7.98E-42 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 SUPERFAMILY SSF110942 511 625 9.29E-30 T 12-10-2018 IPR037196 HSP90, C-terminal domain HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 PIRSF PIRSF002583 1 626 4.6E-206 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 Gene3D G3DSA:3.30.230.80 235 407 2.4E-56 T 12-10-2018 HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 150 4.3E-13 T 12-10-2018 HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 Hamap MF_00505 Chaperone protein HtpG [htpG]. 2 626 26.956 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 Pfam PF00183 Hsp90 protein 184 230 1.2E-7 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 Pfam PF00183 Hsp90 protein 220 625 1.1E-112 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 PRINTS PR00775 90kDa heat shock protein signature 23 45 4.2E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 PRINTS PR00775 90kDa heat shock protein signature 188 206 4.2E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 PRINTS PR00775 90kDa heat shock protein signature 2 22 4.2E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 PRINTS PR00775 90kDa heat shock protein signature 165 182 4.2E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 PRINTS PR00775 90kDa heat shock protein signature 72 89 4.2E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 PRINTS PR00775 90kDa heat shock protein signature 115 137 4.2E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 PRINTS PR00775 90kDa heat shock protein signature 90 107 4.2E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 SUPERFAMILY SSF54211 236 488 6.45E-83 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 Gene3D G3DSA:1.20.120.790 495 626 3.7E-36 T 12-10-2018 IPR037196 HSP90, C-terminal domain HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 12-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 Gene3D G3DSA:3.40.50.11260 408 494 2.0E-27 T 12-10-2018 HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 SUPERFAMILY SSF55874 1 212 3.01E-64 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 SMART SM00387 24 177 0.0096 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_17455 38f9a0a252f2d7141009fad118b1cdbe 626 Gene3D G3DSA:3.30.565.10 1 228 3.2E-74 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_13480 3badd2987a20295c7ac85c3ced65a536 187 Gene3D G3DSA:3.30.70.20 2 179 4.8E-32 T 12-10-2018 HW35_13480 3badd2987a20295c7ac85c3ced65a536 187 SUPERFAMILY SSF54862 6 157 1.88E-39 T 12-10-2018 HW35_13480 3badd2987a20295c7ac85c3ced65a536 187 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_13480 3badd2987a20295c7ac85c3ced65a536 187 Pfam PF13247 4Fe-4S dicluster domain 48 138 8.9E-22 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HW35_13480 3badd2987a20295c7ac85c3ced65a536 187 Pfam PF12800 4Fe-4S binding domain 11 24 0.058 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HW35_15265 ce69e734c91f963e740af8f40d89efcf 339 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_15265 ce69e734c91f963e740af8f40d89efcf 339 Gene3D G3DSA:3.40.50.300 10 338 1.0E-100 T 12-10-2018 HW35_15265 ce69e734c91f963e740af8f40d89efcf 339 SMART SM00382 41 241 2.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_15265 ce69e734c91f963e740af8f40d89efcf 339 SUPERFAMILY SSF52540 12 261 4.63E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15265 ce69e734c91f963e740af8f40d89efcf 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 327 5.7E-29 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_15265 ce69e734c91f963e740af8f40d89efcf 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 308 1.9E-20 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_15265 ce69e734c91f963e740af8f40d89efcf 339 Pfam PF00005 ABC transporter 32 191 2.9E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_11155 561171440dbf20dbc72df6e1c7bfde4e 174 Pfam PF09335 SNARE associated Golgi protein 25 141 2.3E-18 T 12-10-2018 IPR032816 SNARE associated Golgi protein HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 318.142 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 Gene3D G3DSA:3.30.70.3380 377 488 3.3E-44 T 12-10-2018 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 2.9E-53 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 3.0E-52 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 SMART SM00838 410 495 4.0E-4 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 Gene3D G3DSA:3.30.70.2570 489 563 7.8E-36 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 Pfam PF00679 Elongation factor G C-terminus 408 495 1.8E-25 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 SUPERFAMILY SSF54980 408 503 6.71E-27 T 12-10-2018 IPR035647 EF-G domain III/V-like HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 Pfam PF03144 Elongation factor Tu domain 2 214 284 1.1E-11 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 PRINTS PR00315 GTP-binding elongation factor signature 83 93 3.9E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 PRINTS PR00315 GTP-binding elongation factor signature 99 110 3.9E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.9E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 PRINTS PR00315 GTP-binding elongation factor signature 135 144 3.9E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.9E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 Gene3D G3DSA:3.40.50.300 9 194 3.5E-75 T 12-10-2018 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 SUPERFAMILY SSF50447 175 297 1.75E-33 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 Gene3D G3DSA:3.30.70.870 295 376 9.7E-37 T 12-10-2018 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 183 1.1E-18 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 Gene3D G3DSA:2.40.30.10 195 294 2.7E-36 T 12-10-2018 HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 SUPERFAMILY SSF52540 9 214 2.55E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04560 693b883af1ae1e2718ddfe0ff3f5d349 611 SUPERFAMILY SSF54980 301 379 9.35E-19 T 12-10-2018 IPR035647 EF-G domain III/V-like HW35_00930 652648b05dd67d546237a7d57cb9e434 134 SUPERFAMILY SSF49764 36 121 4.36E-13 T 12-10-2018 IPR008978 HSP20-like chaperone HW35_00930 652648b05dd67d546237a7d57cb9e434 134 Pfam PF00011 Hsp20/alpha crystallin family 41 128 1.6E-5 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain HW35_00930 652648b05dd67d546237a7d57cb9e434 134 Gene3D G3DSA:2.60.40.790 31 122 3.0E-12 T 12-10-2018 IPR008978 HSP20-like chaperone HW35_16210 add06fd052684533b58151e4abdf8b25 259 Pfam PF01734 Patatin-like phospholipase 8 164 2.6E-21 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 HW35_16210 add06fd052684533b58151e4abdf8b25 259 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 11 43 - T 12-10-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 HW35_16210 add06fd052684533b58151e4abdf8b25 259 Gene3D G3DSA:3.40.1090.10 100 218 4.2E-22 T 12-10-2018 HW35_16210 add06fd052684533b58151e4abdf8b25 259 Gene3D G3DSA:3.40.1090.10 1 99 7.7E-27 T 12-10-2018 HW35_16210 add06fd052684533b58151e4abdf8b25 259 SUPERFAMILY SSF52151 1 255 6.1E-60 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase HW35_13580 e4c2a09ba4d37df4c8c028e510d1e709 510 Gene3D G3DSA:3.50.50.60 33 381 9.1E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_13580 e4c2a09ba4d37df4c8c028e510d1e709 510 Gene3D G3DSA:2.102.10.10 409 510 8.4E-25 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 HW35_13580 e4c2a09ba4d37df4c8c028e510d1e709 510 Pfam PF01266 FAD dependent oxidoreductase 33 378 1.5E-45 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HW35_13580 e4c2a09ba4d37df4c8c028e510d1e709 510 SUPERFAMILY SSF50022 421 507 3.14E-25 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 HW35_13580 e4c2a09ba4d37df4c8c028e510d1e709 510 PRINTS PR00162 Rieske 2Fe-2S subunit signature 492 504 1.8E-8 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 HW35_13580 e4c2a09ba4d37df4c8c028e510d1e709 510 PRINTS PR00162 Rieske 2Fe-2S subunit signature 480 492 1.8E-8 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 HW35_13580 e4c2a09ba4d37df4c8c028e510d1e709 510 PRINTS PR00162 Rieske 2Fe-2S subunit signature 459 470 1.8E-8 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 HW35_13580 e4c2a09ba4d37df4c8c028e510d1e709 510 Pfam PF00355 Rieske [2Fe-2S] domain 428 505 2.5E-15 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 HW35_13580 e4c2a09ba4d37df4c8c028e510d1e709 510 Gene3D G3DSA:3.30.9.10 126 339 9.1E-48 T 12-10-2018 HW35_13580 e4c2a09ba4d37df4c8c028e510d1e709 510 SUPERFAMILY SSF51905 30 384 3.37E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 SUPERFAMILY SSF51412 4 157 8.7E-30 T 12-10-2018 HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 Pfam PF00571 CBS domain 153 204 3.7E-9 T 12-10-2018 IPR000644 CBS domain HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 Pfam PF00571 CBS domain 97 144 1.5E-6 T 12-10-2018 IPR000644 CBS domain HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 Gene3D G3DSA:3.20.20.70 1 487 1.7E-226 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 455 3.2E-204 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 SUPERFAMILY SSF51412 143 485 6.28E-127 T 12-10-2018 HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 SMART SM01240 9 474 0.0 T 12-10-2018 HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 PIRSF PIRSF000130 1 488 2.6E-212 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 SMART SM00116 161 209 1.4E-9 T 12-10-2018 IPR000644 CBS domain HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 SMART SM00116 98 148 2.5E-7 T 12-10-2018 IPR000644 CBS domain HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 474 2.3E-166 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 HW35_10040 0b1f34664b76de0a0247f98f07e920c0 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 487 86.103 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 HW35_01045 9fffae55388c264a2398c19b11c35155 362 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 33 112 6.0E-5 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HW35_01045 9fffae55388c264a2398c19b11c35155 362 SUPERFAMILY SSF56349 185 348 5.3E-35 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HW35_01045 9fffae55388c264a2398c19b11c35155 362 Pfam PF00589 Phage integrase family 178 343 8.0E-32 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HW35_01045 9fffae55388c264a2398c19b11c35155 362 Gene3D G3DSA:1.10.443.10 172 362 5.4E-44 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 HW35_01045 9fffae55388c264a2398c19b11c35155 362 Gene3D G3DSA:1.10.150.130 20 144 1.9E-13 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal HW35_00965 9e7c602cc067b81db87a50948331e928 567 Pfam PF00005 ABC transporter 23 149 1.2E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_00965 9e7c602cc067b81db87a50948331e928 567 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_00965 9e7c602cc067b81db87a50948331e928 567 SUPERFAMILY SSF52540 295 501 7.33E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_00965 9e7c602cc067b81db87a50948331e928 567 Pfam PF00005 ABC transporter 325 453 9.4E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_00965 9e7c602cc067b81db87a50948331e928 567 SMART SM00382 333 503 2.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_00965 9e7c602cc067b81db87a50948331e928 567 SMART SM00382 32 194 2.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_00965 9e7c602cc067b81db87a50948331e928 567 SUPERFAMILY SSF52540 5 228 1.43E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_00965 9e7c602cc067b81db87a50948331e928 567 Pfam PF12848 ABC transporter 188 288 1.3E-11 T 12-10-2018 IPR032781 ABC-transporter extension domain HW35_00965 9e7c602cc067b81db87a50948331e928 567 Gene3D G3DSA:3.40.50.300 1 232 2.0E-55 T 12-10-2018 HW35_00965 9e7c602cc067b81db87a50948331e928 567 Gene3D G3DSA:3.40.50.300 270 530 5.3E-58 T 12-10-2018 HW35_02460 48476f196108501ab646a04d7b13f8ac 419 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 4.5E-47 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_02460 48476f196108501ab646a04d7b13f8ac 419 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 1.4E-133 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_02460 48476f196108501ab646a04d7b13f8ac 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_02460 48476f196108501ab646a04d7b13f8ac 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_02460 48476f196108501ab646a04d7b13f8ac 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_02460 48476f196108501ab646a04d7b13f8ac 419 Pfam PF08388 Group II intron, maturase-specific domain 288 360 6.7E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_02460 48476f196108501ab646a04d7b13f8ac 419 SUPERFAMILY SSF56672 16 356 3.78E-62 T 12-10-2018 HW35_03315 9328473f8843e80c409a372b70baa24f 428 ProSitePatterns PS00885 EPSP synthase signature 2. 341 359 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HW35_03315 9328473f8843e80c409a372b70baa24f 428 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 427 3.4E-132 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HW35_03315 9328473f8843e80c409a372b70baa24f 428 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 428 33.338 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HW35_03315 9328473f8843e80c409a372b70baa24f 428 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HW35_03315 9328473f8843e80c409a372b70baa24f 428 PIRSF PIRSF000505 1 428 2.1E-119 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HW35_03315 9328473f8843e80c409a372b70baa24f 428 SUPERFAMILY SSF55205 9 427 1.8E-136 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HW35_03315 9328473f8843e80c409a372b70baa24f 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 424 5.0E-125 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HW35_03315 9328473f8843e80c409a372b70baa24f 428 Gene3D G3DSA:3.65.10.10 23 231 1.5E-156 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 HW35_03315 9328473f8843e80c409a372b70baa24f 428 Gene3D G3DSA:3.65.10.10 15 424 1.5E-156 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 HW35_01795 f4cc569f94791d527339c0d0ee2eec3d 350 Pfam PF01008 Initiation factor 2 subunit family 52 332 2.3E-73 T 12-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 HW35_01795 f4cc569f94791d527339c0d0ee2eec3d 350 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 38 332 4.8E-99 T 12-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HW35_01795 f4cc569f94791d527339c0d0ee2eec3d 350 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 13 332 2.1E-108 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HW35_01795 f4cc569f94791d527339c0d0ee2eec3d 350 Gene3D G3DSA:1.20.120.420 6 139 2.9E-32 T 12-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HW35_01795 f4cc569f94791d527339c0d0ee2eec3d 350 Gene3D G3DSA:3.40.50.10470 140 340 1.8E-66 T 12-10-2018 HW35_01795 f4cc569f94791d527339c0d0ee2eec3d 350 SUPERFAMILY SSF100950 12 337 4.88E-101 T 12-10-2018 IPR037171 NagB/RpiA transferase-like HW35_10655 b6994b216afd3c2486816e12c316e35a 232 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 8.7E-57 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein HW35_10655 b6994b216afd3c2486816e12c316e35a 232 Gene3D G3DSA:3.40.50.790 68 159 2.5E-86 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich HW35_10655 b6994b216afd3c2486816e12c316e35a 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 1.3E-109 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 HW35_10655 b6994b216afd3c2486816e12c316e35a 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 45.381 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 HW35_10655 b6994b216afd3c2486816e12c316e35a 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10655 b6994b216afd3c2486816e12c316e35a 232 PIRSF PIRSF002155 1 227 2.7E-84 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10655 b6994b216afd3c2486816e12c316e35a 232 SUPERFAMILY SSF56808 6 226 1.96E-86 T 12-10-2018 IPR023674 Ribosomal protein L1-like HW35_10655 b6994b216afd3c2486816e12c316e35a 232 Gene3D G3DSA:3.30.190.20 21 225 2.5E-86 T 12-10-2018 HW35_05675 82ae83fc893ad820958d622ea124c9e6 154 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 21 131 1.0E-35 T 12-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame HW35_05675 82ae83fc893ad820958d622ea124c9e6 154 Pfam PF04284 Protein of unknown function (DUF441) 7 144 3.1E-49 T 12-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame HW35_05675 82ae83fc893ad820958d622ea124c9e6 154 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 149 18.775 T 12-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame HW35_07670 ebc1698a25175e1ceb680f2420b319f9 390 Gene3D G3DSA:3.30.930.10 1 324 3.4E-99 T 12-10-2018 HW35_07670 ebc1698a25175e1ceb680f2420b319f9 390 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 19 373 30.802 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 HW35_07670 ebc1698a25175e1ceb680f2420b319f9 390 Gene3D G3DSA:3.40.50.12590 326 390 1.6E-14 T 12-10-2018 HW35_07670 ebc1698a25175e1ceb680f2420b319f9 390 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 14 323 6.9E-96 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 HW35_07670 ebc1698a25175e1ceb680f2420b319f9 390 Pfam PF13393 Histidyl-tRNA synthetase 12 319 1.4E-74 T 12-10-2018 HW35_07670 ebc1698a25175e1ceb680f2420b319f9 390 SUPERFAMILY SSF55681 7 326 3.13E-60 T 12-10-2018 HW35_07670 ebc1698a25175e1ceb680f2420b319f9 390 PIRSF PIRSF001549 3 382 1.9E-77 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Gene3D G3DSA:1.10.1790.10 190 288 1.4E-12 T 12-10-2018 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Pfam PF00874 PRD domain 307 397 1.3E-20 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Pfam PF00874 PRD domain 198 285 4.6E-14 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Gene3D G3DSA:1.10.1790.10 299 400 2.4E-22 T 12-10-2018 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Gene3D G3DSA:3.40.50.2300 408 495 3.9E-9 T 12-10-2018 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 SUPERFAMILY SSF63520 299 400 2.75E-23 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Gene3D G3DSA:1.10.10.10 83 156 4.1E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Gene3D G3DSA:1.10.10.10 2 72 1.4E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Pfam PF05043 Mga helix-turn-helix domain 96 168 6.5E-7 T 12-10-2018 IPR007737 Mga helix-turn-helix domain HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 523 645 1.5E-26 T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 SUPERFAMILY SSF63520 192 286 1.06E-15 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 SUPERFAMILY SSF52794 407 487 3.92E-9 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Pfam PF08279 HTH domain 11 69 8.4E-11 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 553 569 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 SUPERFAMILY SSF55804 506 645 9.03E-30 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 SUPERFAMILY SSF46785 8 53 9.58E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_08715 35c87d12c4b26b79c8eb0fc394567b57 646 Gene3D G3DSA:3.40.930.10 510 646 2.1E-26 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 SUPERFAMILY SSF82693 40 131 2.27E-19 T 12-10-2018 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 Pfam PF00873 AcrB/AcrD/AcrF family 3 1023 8.7E-247 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 SUPERFAMILY SSF82693 159 332 6.28E-9 T 12-10-2018 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 SUPERFAMILY SSF82866 801 1028 2.75E-55 T 12-10-2018 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 Gene3D G3DSA:1.20.1640.10 10 514 3.5E-297 T 12-10-2018 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 Gene3D G3DSA:3.30.2090.10 186 278 3.5E-297 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 Gene3D G3DSA:3.30.70.1430 40 813 3.5E-297 T 12-10-2018 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 Gene3D G3DSA:3.30.70.1440 668 863 3.5E-297 T 12-10-2018 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 PRINTS PR00702 Acriflavin resistance protein family signature 473 496 1.8E-61 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 1.8E-61 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 PRINTS PR00702 Acriflavin resistance protein family signature 367 388 1.8E-61 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 PRINTS PR00702 Acriflavin resistance protein family signature 448 471 1.8E-61 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.8E-61 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 PRINTS PR00702 Acriflavin resistance protein family signature 340 363 1.8E-61 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 PRINTS PR00702 Acriflavin resistance protein family signature 547 564 1.8E-61 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.8E-61 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 PRINTS PR00702 Acriflavin resistance protein family signature 395 419 1.8E-61 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 SUPERFAMILY SSF82714 718 803 3.79E-10 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 Gene3D G3DSA:1.20.1640.10 515 1020 3.5E-297 T 12-10-2018 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 Gene3D G3DSA:3.30.70.1320 132 336 3.5E-297 T 12-10-2018 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 SUPERFAMILY SSF82866 300 501 1.57E-48 T 12-10-2018 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 SUPERFAMILY SSF82693 561 649 4.19E-10 T 12-10-2018 HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 SUPERFAMILY SSF82714 191 273 1.83E-11 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 Gene3D G3DSA:3.30.2090.10 716 805 3.5E-297 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HW35_08170 cb7fa65c4a31b86c1180d945a1109485 1036 Gene3D G3DSA:3.30.70.1430 562 667 3.5E-297 T 12-10-2018 HW35_10285 870735b5276b39ea764b3faeda485516 1178 SMART SM01058 499 596 2.0E-51 T 12-10-2018 IPR003711 CarD-like/TRCF domain HW35_10285 870735b5276b39ea764b3faeda485516 1178 SUPERFAMILY SSF143517 1013 1164 8.37E-36 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain HW35_10285 870735b5276b39ea764b3faeda485516 1178 SUPERFAMILY SSF52540 377 489 3.08E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10285 870735b5276b39ea764b3faeda485516 1178 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 38 1118 28.944 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 HW35_10285 870735b5276b39ea764b3faeda485516 1178 SMART SM00487 620 810 4.6E-35 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_10285 870735b5276b39ea764b3faeda485516 1178 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 158 1098 0.0 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 HW35_10285 870735b5276b39ea764b3faeda485516 1178 SUPERFAMILY SSF52540 543 803 1.52E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10285 870735b5276b39ea764b3faeda485516 1178 Gene3D G3DSA:3.40.50.300 498 1009 5.4E-246 T 12-10-2018 HW35_10285 870735b5276b39ea764b3faeda485516 1178 Gene3D G3DSA:2.30.30.840 503 561 5.4E-246 T 12-10-2018 HW35_10285 870735b5276b39ea764b3faeda485516 1178 Gene3D G3DSA:3.40.50.300 562 801 5.4E-246 T 12-10-2018 HW35_10285 870735b5276b39ea764b3faeda485516 1178 Pfam PF00270 DEAD/DEAH box helicase 625 784 4.4E-17 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HW35_10285 870735b5276b39ea764b3faeda485516 1178 Pfam PF03461 TRCF domain 1025 1113 8.2E-27 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 HW35_10285 870735b5276b39ea764b3faeda485516 1178 Pfam PF00271 Helicase conserved C-terminal domain 829 929 4.7E-18 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_10285 870735b5276b39ea764b3faeda485516 1178 Pfam PF02559 CarD-like/TRCF domain 500 595 4.4E-32 T 12-10-2018 IPR003711 CarD-like/TRCF domain HW35_10285 870735b5276b39ea764b3faeda485516 1178 SUPERFAMILY SSF52540 14 368 2.13E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10285 870735b5276b39ea764b3faeda485516 1178 Gene3D G3DSA:3.40.50.11180 35 328 2.3E-67 T 12-10-2018 HW35_10285 870735b5276b39ea764b3faeda485516 1178 SUPERFAMILY SSF52540 802 1009 9.25E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10285 870735b5276b39ea764b3faeda485516 1178 SUPERFAMILY SSF141259 490 568 2.88E-26 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily HW35_10285 870735b5276b39ea764b3faeda485516 1178 Gene3D G3DSA:3.90.1150.50 1020 1178 9.9E-41 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain HW35_10285 870735b5276b39ea764b3faeda485516 1178 SMART SM00490 846 930 4.8E-21 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_10285 870735b5276b39ea764b3faeda485516 1178 Gene3D G3DSA:3.30.2060.10 140 225 2.3E-67 T 12-10-2018 HW35_10285 870735b5276b39ea764b3faeda485516 1178 SMART SM00982 1024 1125 1.5E-37 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 HW35_17020 c1b3e1389a44c22ec193cbbc02a3fc25 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 264 8.6E-22 T 12-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal HW35_17020 c1b3e1389a44c22ec193cbbc02a3fc25 288 Gene3D G3DSA:3.40.50.970 73 214 5.7E-27 T 12-10-2018 HW35_17020 c1b3e1389a44c22ec193cbbc02a3fc25 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 269 2.1E-98 T 12-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate HW35_17020 c1b3e1389a44c22ec193cbbc02a3fc25 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 6.4E-33 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HW35_17020 c1b3e1389a44c22ec193cbbc02a3fc25 288 SUPERFAMILY SSF52518 12 286 2.58E-79 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_11430 1425da43ed96700d21478e1da8fdbd8f 116 SUPERFAMILY SSF50118 2 113 3.43E-42 T 12-10-2018 HW35_11430 1425da43ed96700d21478e1da8fdbd8f 116 PIRSF PIRSF033490 1 113 3.8E-40 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 HW35_11430 1425da43ed96700d21478e1da8fdbd8f 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 9.2E-34 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 HW35_11430 1425da43ed96700d21478e1da8fdbd8f 116 Gene3D G3DSA:2.30.30.110 1 116 2.0E-53 T 12-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 467 7.0E-134 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 12-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 PIRSF PIRSF000109 1 470 1.2E-233 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 Gene3D G3DSA:1.20.5.320 436 469 9.7E-22 T 12-10-2018 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 Gene3D G3DSA:3.40.50.720 1 179 9.7E-56 T 12-10-2018 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 173 2.3E-48 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 Gene3D G3DSA:1.10.1040.10 180 435 3.5E-109 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 SUPERFAMILY SSF51735 4 176 2.63E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 SUPERFAMILY SSF48179 176 469 4.28E-131 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 468 6.8E-222 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 1.1E-85 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 1.1E-85 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 1.1E-85 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 1.1E-85 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 1.1E-85 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 1.1E-85 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_06850 cea81d979443b8012fb62f8a09ac784a 470 SMART SM01350 178 468 1.9E-225 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HW35_01655 922ed99de07cdf941a5594877d761186 251 Pfam PF00565 Staphylococcal nuclease homologue 71 178 4.7E-34 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 HW35_01655 922ed99de07cdf941a5594877d761186 251 SMART SM00318 45 179 1.3E-39 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 HW35_01655 922ed99de07cdf941a5594877d761186 251 ProSitePatterns PS01284 Thermonuclease family signature 2. 120 130 - T 12-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 HW35_01655 922ed99de07cdf941a5594877d761186 251 SUPERFAMILY SSF50199 45 182 5.62E-37 T 12-10-2018 HW35_01655 922ed99de07cdf941a5594877d761186 251 Gene3D G3DSA:2.40.50.90 37 185 3.2E-53 T 12-10-2018 IPR035437 SNase-like, OB-fold superfamily HW35_14420 a2eae2c5458a2b0ef342b3cd9c0543fa 319 SUPERFAMILY SSF56349 25 305 6.77E-59 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HW35_14420 a2eae2c5458a2b0ef342b3cd9c0543fa 319 Gene3D G3DSA:1.10.443.10 128 319 8.0E-44 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 HW35_14420 a2eae2c5458a2b0ef342b3cd9c0543fa 319 Pfam PF00589 Phage integrase family 132 298 5.2E-33 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HW35_14420 a2eae2c5458a2b0ef342b3cd9c0543fa 319 Gene3D G3DSA:1.10.150.130 21 127 2.6E-20 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal HW35_14420 a2eae2c5458a2b0ef342b3cd9c0543fa 319 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 31 110 1.7E-12 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HW35_16650 6e5e8a08481382cd58ff702ddfc36cab 78 Hamap MF_01217 Acyl carrier protein [acpP]. 4 78 22.747 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HW35_16650 6e5e8a08481382cd58ff702ddfc36cab 78 Pfam PF00550 Phosphopantetheine attachment site 8 74 1.3E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain HW35_16650 6e5e8a08481382cd58ff702ddfc36cab 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 33 48 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site HW35_16650 6e5e8a08481382cd58ff702ddfc36cab 78 SUPERFAMILY SSF47336 4 77 8.38E-23 T 12-10-2018 IPR036736 ACP-like superfamily HW35_16650 6e5e8a08481382cd58ff702ddfc36cab 78 Gene3D G3DSA:1.10.1200.10 2 78 3.2E-29 T 12-10-2018 IPR036736 ACP-like superfamily HW35_16650 6e5e8a08481382cd58ff702ddfc36cab 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 4 78 2.6E-34 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 Pfam PF07478 D-ala D-ala ligase C-terminus 140 342 2.5E-84 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 344 2.0E-117 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 SUPERFAMILY SSF52440 1 131 1.82E-35 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HW35_11385 477c6efda9f891d9530916eb8f922db0 358 Gene3D G3DSA:3.30.1490.20 147 219 2.9E-30 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 287 315 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 345 42.013 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 Gene3D G3DSA:3.40.50.20 1 120 5.6E-35 T 12-10-2018 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 99 110 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 PIRSF PIRSF039102 1 353 5.8E-116 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 Pfam PF01820 D-ala D-ala ligase N-terminus 4 121 1.8E-28 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 SUPERFAMILY SSF56059 132 349 7.81E-63 T 12-10-2018 HW35_11385 477c6efda9f891d9530916eb8f922db0 358 Gene3D G3DSA:3.30.470.20 220 358 7.1E-54 T 12-10-2018 HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 7.0E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 7.0E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 64 320 7.9E-29 T 12-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 51 2.0E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 SMART SM00354 3 74 7.6E-32 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 SUPERFAMILY SSF53822 64 325 6.06E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 Gene3D G3DSA:3.40.50.2300 162 292 1.9E-72 T 12-10-2018 HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 12-10-2018 HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 SUPERFAMILY SSF47413 2 62 5.63E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 Gene3D G3DSA:1.10.260.40 1 62 1.7E-22 T 12-10-2018 HW35_08375 31833c5f0d8975a339d8b8d03ac66d7d 326 Gene3D G3DSA:3.40.50.2300 66 313 1.9E-72 T 12-10-2018 HW35_07365 c004dbb28b6b8f61b97b6d43512493a3 248 Gene3D G3DSA:3.40.50.1820 1 246 8.7E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_07365 c004dbb28b6b8f61b97b6d43512493a3 248 Pfam PF12146 Serine aminopeptidase, S33 17 229 6.9E-19 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 HW35_07365 c004dbb28b6b8f61b97b6d43512493a3 248 PIRSF PIRSF017388 1 246 2.9E-99 T 12-10-2018 IPR012354 Esterase/lipase GO:0052689 HW35_07365 c004dbb28b6b8f61b97b6d43512493a3 248 SUPERFAMILY SSF53474 11 245 1.11E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_02160 b69598e062ce5edf2bd3442f5ade553f 83 ProDom PD059965 SASP SPORULATION-SPECIFIC SIGMA-G-DEPENDENT SPORULATION SPECIFIC CSGA 1 83 2.0E-19 T 12-10-2018 IPR020255 Sigma-G-dependent sporulation-specific SASP protein HW35_02160 b69598e062ce5edf2bd3442f5ade553f 83 Pfam PF17334 Sigma-G-dependent sporulation-specific SASP protein 1 83 3.5E-38 T 12-10-2018 IPR020255 Sigma-G-dependent sporulation-specific SASP protein HW35_16915 6b16a6fad272fee04bfa509557a10e3d 76 Pfam PF14035 YlzJ-like protein 3 67 2.0E-23 T 12-10-2018 IPR025619 YlzJ-like protein HW35_02845 68ca81705c1683f090849ed158635f84 162 PRINTS PR00070 Dihydrofolate reductase signature 92 106 2.3E-15 T 12-10-2018 HW35_02845 68ca81705c1683f090849ed158635f84 162 PRINTS PR00070 Dihydrofolate reductase signature 27 35 2.3E-15 T 12-10-2018 HW35_02845 68ca81705c1683f090849ed158635f84 162 PRINTS PR00070 Dihydrofolate reductase signature 40 51 2.3E-15 T 12-10-2018 HW35_02845 68ca81705c1683f090849ed158635f84 162 PRINTS PR00070 Dihydrofolate reductase signature 13 23 2.3E-15 T 12-10-2018 HW35_02845 68ca81705c1683f090849ed158635f84 162 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 12-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 HW35_02845 68ca81705c1683f090849ed158635f84 162 SUPERFAMILY SSF53597 1 161 1.39E-61 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 HW35_02845 68ca81705c1683f090849ed158635f84 162 Pfam PF00186 Dihydrofolate reductase 1 160 7.8E-67 T 12-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 HW35_02845 68ca81705c1683f090849ed158635f84 162 Gene3D G3DSA:3.40.430.10 1 162 9.8E-64 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 HW35_02845 68ca81705c1683f090849ed158635f84 162 PIRSF PIRSF000194 1 162 3.1E-65 T 12-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 HW35_05870 8ea0b2f5164896f8f95f9ecf280cb4a4 159 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 12-10-2018 IPR000614 Free Met sulfoxide reductase conserved site HW35_05870 8ea0b2f5164896f8f95f9ecf280cb4a4 159 Gene3D G3DSA:3.30.450.40 2 159 1.2E-66 T 12-10-2018 IPR029016 GAF-like domain superfamily HW35_05870 8ea0b2f5164896f8f95f9ecf280cb4a4 159 Pfam PF13185 GAF domain 53 153 4.4E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 HW35_05870 8ea0b2f5164896f8f95f9ecf280cb4a4 159 SUPERFAMILY SSF55781 21 158 2.62E-43 T 12-10-2018 HW35_03185 38a407c37a9cae8c121645fed6eddb07 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 HW35_03185 38a407c37a9cae8c121645fed6eddb07 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 229 253 3.0E-17 T 12-10-2018 HW35_03185 38a407c37a9cae8c121645fed6eddb07 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 93 113 3.0E-17 T 12-10-2018 HW35_03185 38a407c37a9cae8c121645fed6eddb07 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 115 136 3.0E-17 T 12-10-2018 HW35_03185 38a407c37a9cae8c121645fed6eddb07 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 198 221 3.0E-17 T 12-10-2018 HW35_03185 38a407c37a9cae8c121645fed6eddb07 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 162 186 3.0E-17 T 12-10-2018 HW35_03185 38a407c37a9cae8c121645fed6eddb07 396 Gene3D G3DSA:3.90.1150.10 26 386 6.1E-144 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_03185 38a407c37a9cae8c121645fed6eddb07 396 SUPERFAMILY SSF53383 1 391 7.71E-121 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_03185 38a407c37a9cae8c121645fed6eddb07 396 Pfam PF00155 Aminotransferase class I and II 31 386 9.3E-84 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HW35_03185 38a407c37a9cae8c121645fed6eddb07 396 Gene3D G3DSA:3.40.640.10 63 285 6.1E-144 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_09850 439b708b5ef2d54ae806d2973b6c24f1 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.0E-51 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_09850 439b708b5ef2d54ae806d2973b6c24f1 149 Gene3D G3DSA:3.40.5.10 1 52 6.1E-26 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09850 439b708b5ef2d54ae806d2973b6c24f1 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 2.8E-32 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal HW35_09850 439b708b5ef2d54ae806d2973b6c24f1 149 SUPERFAMILY SSF55658 1 56 2.44E-18 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal HW35_09850 439b708b5ef2d54ae806d2973b6c24f1 149 Gene3D G3DSA:3.10.430.100 60 149 5.9E-34 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily HW35_09850 439b708b5ef2d54ae806d2973b6c24f1 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 2.8E-23 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09850 439b708b5ef2d54ae806d2973b6c24f1 149 SUPERFAMILY SSF55653 58 147 3.14E-30 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily HW35_09850 439b708b5ef2d54ae806d2973b6c24f1 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 26.755 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_09850 439b708b5ef2d54ae806d2973b6c24f1 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10110 c61e2f97d29d8455b726beb46277b77c 87 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 5 86 5.6E-24 T 12-10-2018 IPR010001 SigmaK-factor processing regulatory BofA HW35_10110 c61e2f97d29d8455b726beb46277b77c 87 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 84 2.4E-19 T 12-10-2018 IPR010001 SigmaK-factor processing regulatory BofA HW35_12045 fe1f3ca5782bae318c3eb37473581a1e 426 Pfam PF07690 Major Facilitator Superfamily 15 361 8.8E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_12045 fe1f3ca5782bae318c3eb37473581a1e 426 Gene3D G3DSA:1.20.1250.20 2 404 5.0E-34 T 12-10-2018 HW35_12045 fe1f3ca5782bae318c3eb37473581a1e 426 SUPERFAMILY SSF103473 3 413 6.54E-45 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_03705 a3c2e5dbbe3e30cb6c33beed9747d11d 296 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 296 56.69 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 HW35_03705 a3c2e5dbbe3e30cb6c33beed9747d11d 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 296 55.081 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD HW35_03705 a3c2e5dbbe3e30cb6c33beed9747d11d 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 87 3.5E-21 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HW35_03705 a3c2e5dbbe3e30cb6c33beed9747d11d 296 Pfam PF00589 Phage integrase family 113 282 3.8E-48 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HW35_03705 a3c2e5dbbe3e30cb6c33beed9747d11d 296 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 296 3.5E-117 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 HW35_03705 a3c2e5dbbe3e30cb6c33beed9747d11d 296 Gene3D G3DSA:1.10.443.10 110 290 8.2E-64 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 HW35_03705 a3c2e5dbbe3e30cb6c33beed9747d11d 296 Gene3D G3DSA:1.10.150.130 2 97 4.2E-24 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal HW35_03705 a3c2e5dbbe3e30cb6c33beed9747d11d 296 SUPERFAMILY SSF56349 5 288 2.59E-56 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HW35_09320 8370cbac2211e8cfcc6be6367f787405 290 Pfam PF00491 Arginase family 23 285 1.9E-80 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_09320 8370cbac2211e8cfcc6be6367f787405 290 SUPERFAMILY SSF52768 12 289 1.42E-86 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily HW35_09320 8370cbac2211e8cfcc6be6367f787405 290 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 12-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 HW35_09320 8370cbac2211e8cfcc6be6367f787405 290 TIGRFAM TIGR01230 agmatinase: agmatinase 11 286 1.6E-117 T 12-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 HW35_09320 8370cbac2211e8cfcc6be6367f787405 290 PIRSF PIRSF036979 1 290 1.2E-99 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_09320 8370cbac2211e8cfcc6be6367f787405 290 Gene3D G3DSA:3.40.800.10 16 289 8.2E-96 T 12-10-2018 HW35_06675 57a766f5201ff6a8b6749998b9c981c6 137 Pfam PF12802 MarR family 30 85 4.5E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_06675 57a766f5201ff6a8b6749998b9c981c6 137 SMART SM00347 23 125 8.1E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_06675 57a766f5201ff6a8b6749998b9c981c6 137 Gene3D G3DSA:1.10.10.10 1 137 5.3E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_06675 57a766f5201ff6a8b6749998b9c981c6 137 SUPERFAMILY SSF46785 3 134 1.16E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13160 2e7de6b630105d24f7566bb89a7668eb 347 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 123 5.6E-33 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 HW35_13160 2e7de6b630105d24f7566bb89a7668eb 347 SUPERFAMILY SSF55347 132 311 7.19E-27 T 12-10-2018 HW35_13160 2e7de6b630105d24f7566bb89a7668eb 347 SUPERFAMILY SSF51735 2 181 1.18E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_13160 2e7de6b630105d24f7566bb89a7668eb 347 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 140 214 1.4E-7 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 HW35_13160 2e7de6b630105d24f7566bb89a7668eb 347 Gene3D G3DSA:3.40.50.720 7 319 2.7E-94 T 12-10-2018 HW35_13160 2e7de6b630105d24f7566bb89a7668eb 347 Gene3D G3DSA:3.30.360.10 128 341 2.7E-94 T 12-10-2018 HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 10 445 4.1E-156 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 SUPERFAMILY SSF52467 167 367 9.45E-12 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 SUPERFAMILY SSF52518 13 182 3.6E-38 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 Pfam PF16582 Middle domain of thiamine pyrophosphate 220 403 2.3E-16 T 12-10-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 425 501 9.5E-7 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 PIRSF PIRSF004983 1 577 4.2E-198 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 SUPERFAMILY SSF52518 383 571 1.31E-25 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 Gene3D G3DSA:3.40.50.1220 199 378 2.3E-54 T 12-10-2018 HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 4 570 36.676 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 Gene3D G3DSA:3.40.50.970 381 579 7.6E-62 T 12-10-2018 HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 Gene3D G3DSA:3.40.50.970 1 174 5.8E-73 T 12-10-2018 HW35_06395 eb25c6d44f10f56fe785eb27f66f6d6b 583 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 175 1.4E-40 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 SUPERFAMILY SSF53448 91 309 1.5E-21 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 Gene3D G3DSA:3.90.550.10 77 312 3.9E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 Gene3D G3DSA:1.10.10.10 2 76 2.3E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 Pfam PF12804 MobA-like NTP transferase domain 93 203 3.9E-9 T 12-10-2018 IPR025877 MobA-like NTP transferase HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 Gene3D G3DSA:3.30.200.20 323 418 2.0E-32 T 12-10-2018 HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 Pfam PF01633 Choline/ethanolamine kinase 365 562 2.3E-31 T 12-10-2018 HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 PIRSF PIRSF037383 4 619 2.8E-198 T 12-10-2018 IPR017190 Bifunctional CTP:phosphocholine cytidylyltransferase/choline kinase HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 SUPERFAMILY SSF56112 333 613 7.37E-52 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 Gene3D G3DSA:3.90.1200.10 420 616 7.7E-66 T 12-10-2018 HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 47 1.3E-9 T 12-10-2018 HW35_08050 95fb4b8f8464e324f19d6eb25e38511b 626 SUPERFAMILY SSF46785 5 74 1.25E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_01095 2656c162954b0d3d47868db726d78a54 430 Gene3D G3DSA:3.40.50.720 204 357 2.5E-176 T 12-10-2018 HW35_01095 2656c162954b0d3d47868db726d78a54 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 108 122 7.9E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_01095 2656c162954b0d3d47868db726d78a54 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 230 250 7.9E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_01095 2656c162954b0d3d47868db726d78a54 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 356 367 7.9E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_01095 2656c162954b0d3d47868db726d78a54 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 188 210 7.9E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_01095 2656c162954b0d3d47868db726d78a54 430 Gene3D G3DSA:1.10.8.1210 378 430 1.3E-15 T 12-10-2018 HW35_01095 2656c162954b0d3d47868db726d78a54 430 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 197 428 5.1E-79 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_01095 2656c162954b0d3d47868db726d78a54 430 Gene3D G3DSA:3.40.50.10860 49 184 2.5E-176 T 12-10-2018 HW35_01095 2656c162954b0d3d47868db726d78a54 430 SUPERFAMILY SSF51735 197 429 1.89E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_01095 2656c162954b0d3d47868db726d78a54 430 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 116 129 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_01095 2656c162954b0d3d47868db726d78a54 430 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 52 179 4.9E-55 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_01095 2656c162954b0d3d47868db726d78a54 430 Gene3D G3DSA:1.10.8.1210 26 358 2.5E-176 T 12-10-2018 HW35_01095 2656c162954b0d3d47868db726d78a54 430 SUPERFAMILY SSF53223 21 199 6.4E-67 T 12-10-2018 HW35_01095 2656c162954b0d3d47868db726d78a54 430 PIRSF PIRSF000185 8 430 4.8E-172 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 HW35_01095 2656c162954b0d3d47868db726d78a54 430 SMART SM00839 199 428 2.1E-98 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_01900 87e70b0eb58cf3c66c005e3dfd9c4c29 348 Gene3D G3DSA:1.10.620.20 28 316 1.1E-85 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 HW35_01900 87e70b0eb58cf3c66c005e3dfd9c4c29 348 PIRSF PIRSF000355 3 348 5.7E-105 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01900 87e70b0eb58cf3c66c005e3dfd9c4c29 348 Pfam PF00268 Ribonucleotide reductase, small chain 33 309 5.2E-71 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01900 87e70b0eb58cf3c66c005e3dfd9c4c29 348 SUPERFAMILY SSF47240 24 348 2.63E-82 T 12-10-2018 IPR009078 Ferritin-like superfamily HW35_12350 7048283892411a11725c4e6a1930f44c 418 Gene3D G3DSA:1.10.287.130 204 259 1.5E-16 T 12-10-2018 HW35_12350 7048283892411a11725c4e6a1930f44c 418 SUPERFAMILY SSF47384 197 264 9.22E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_12350 7048283892411a11725c4e6a1930f44c 418 SMART SM00388 201 266 1.1E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_12350 7048283892411a11725c4e6a1930f44c 418 Pfam PF07694 5TMR of 5TMR-LYT 25 180 3.1E-9 T 12-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 HW35_12350 7048283892411a11725c4e6a1930f44c 418 Gene3D G3DSA:1.10.1760.20 28 191 1.1E-5 T 12-10-2018 HW35_12350 7048283892411a11725c4e6a1930f44c 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 307 413 1.0E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_12350 7048283892411a11725c4e6a1930f44c 418 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 264 1.1E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_12350 7048283892411a11725c4e6a1930f44c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 4.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_12350 7048283892411a11725c4e6a1930f44c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 412 4.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_12350 7048283892411a11725c4e6a1930f44c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 4.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_12350 7048283892411a11725c4e6a1930f44c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 4.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_12350 7048283892411a11725c4e6a1930f44c 418 SUPERFAMILY SSF55874 263 415 6.68E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_12350 7048283892411a11725c4e6a1930f44c 418 Gene3D G3DSA:3.30.565.10 260 413 5.8E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_12350 7048283892411a11725c4e6a1930f44c 418 SMART SM00387 307 415 1.8E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_16840 ffb7eb74c469e5400fcdd04e91439d26 123 Gene3D G3DSA:3.30.300.20 1 116 9.4E-40 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta HW35_16840 ffb7eb74c469e5400fcdd04e91439d26 123 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 107 28.426 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 HW35_16840 ffb7eb74c469e5400fcdd04e91439d26 123 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 2 112 1.7E-41 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 HW35_16840 ffb7eb74c469e5400fcdd04e91439d26 123 SUPERFAMILY SSF89919 2 110 2.88E-36 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily HW35_16840 ffb7eb74c469e5400fcdd04e91439d26 123 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 94 3.0E-39 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 HW35_16840 ffb7eb74c469e5400fcdd04e91439d26 123 Pfam PF02033 Ribosome-binding factor A 4 107 9.2E-35 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 HW35_16840 ffb7eb74c469e5400fcdd04e91439d26 123 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 12-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 HW35_04550 e8af8768020bb97fd958725aae2e440e 341 Gene3D G3DSA:3.30.450.40 104 336 2.2E-61 T 12-10-2018 IPR029016 GAF-like domain superfamily HW35_04550 e8af8768020bb97fd958725aae2e440e 341 Gene3D G3DSA:3.30.390.60 128 229 2.2E-61 T 12-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily HW35_04550 e8af8768020bb97fd958725aae2e440e 341 Pfam PF01628 HrcA protein C terminal domain 104 322 6.2E-63 T 12-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 HW35_04550 e8af8768020bb97fd958725aae2e440e 341 PIRSF PIRSF005485 1 340 1.7E-123 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 HW35_04550 e8af8768020bb97fd958725aae2e440e 341 SUPERFAMILY SSF46785 2 84 1.82E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_04550 e8af8768020bb97fd958725aae2e440e 341 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 335 5.2E-113 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 HW35_04550 e8af8768020bb97fd958725aae2e440e 341 SUPERFAMILY SSF55781 71 339 5.1E-67 T 12-10-2018 HW35_04550 e8af8768020bb97fd958725aae2e440e 341 Gene3D G3DSA:1.10.10.10 1 84 1.8E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_04550 e8af8768020bb97fd958725aae2e440e 341 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 329 33.487 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 HW35_03555 a158e679b2d76032649f957b96b6de61 593 Gene3D G3DSA:1.10.287.130 362 437 9.2E-26 T 12-10-2018 HW35_03555 a158e679b2d76032649f957b96b6de61 593 Gene3D G3DSA:3.30.450.20 259 361 1.2E-9 T 12-10-2018 HW35_03555 a158e679b2d76032649f957b96b6de61 593 SMART SM00304 198 250 8.0E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_03555 a158e679b2d76032649f957b96b6de61 593 Pfam PF00989 PAS fold 257 359 1.7E-7 T 12-10-2018 IPR013767 PAS fold GO:0006355 HW35_03555 a158e679b2d76032649f957b96b6de61 593 SMART SM00091 257 324 0.0045 T 12-10-2018 IPR000014 PAS domain HW35_03555 a158e679b2d76032649f957b96b6de61 593 Gene3D G3DSA:3.30.565.10 438 593 6.6E-52 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_03555 a158e679b2d76032649f957b96b6de61 593 Pfam PF00512 His Kinase A (phospho-acceptor) domain 368 435 4.1E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_03555 a158e679b2d76032649f957b96b6de61 593 SMART SM00388 368 435 3.1E-21 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_03555 a158e679b2d76032649f957b96b6de61 593 SMART SM00387 481 593 2.5E-43 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_03555 a158e679b2d76032649f957b96b6de61 593 Gene3D G3DSA:1.20.1480.50 161 256 2.2E-19 T 12-10-2018 HW35_03555 a158e679b2d76032649f957b96b6de61 593 SUPERFAMILY SSF55874 424 591 3.41E-52 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_03555 a158e679b2d76032649f957b96b6de61 593 SUPERFAMILY SSF47384 352 436 5.1E-21 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_03555 a158e679b2d76032649f957b96b6de61 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 482 591 2.0E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_03555 a158e679b2d76032649f957b96b6de61 593 SUPERFAMILY SSF55785 245 360 6.11E-9 T 12-10-2018 IPR035965 PAS domain superfamily HW35_03555 a158e679b2d76032649f957b96b6de61 593 SUPERFAMILY SSF158472 199 246 2.09E-10 T 12-10-2018 HW35_03555 a158e679b2d76032649f957b96b6de61 593 Pfam PF00672 HAMP domain 199 245 6.8E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_03555 a158e679b2d76032649f957b96b6de61 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 532 5.4E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_03555 a158e679b2d76032649f957b96b6de61 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 546 5.4E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_03555 a158e679b2d76032649f957b96b6de61 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 571 5.4E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_03555 a158e679b2d76032649f957b96b6de61 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 577 590 5.4E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_14675 15a9e88889912fe30833d7637370d5f2 205 Pfam PF01865 Protein of unknown function DUF47 8 202 1.5E-25 T 12-10-2018 IPR018445 Putative phosphate transport regulator HW35_14675 15a9e88889912fe30833d7637370d5f2 205 Gene3D G3DSA:1.20.58.220 9 205 2.3E-56 T 12-10-2018 IPR038078 PhoU-like domain superfamily HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 SUPERFAMILY SSF48019 244 362 4.42E-25 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 SMART SM00382 37 179 9.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 Gene3D G3DSA:1.20.272.10 242 364 2.8E-5 T 12-10-2018 HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 4.3E-6 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 4.3E-6 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 Gene3D G3DSA:3.40.50.300 13 177 3.3E-105 T 12-10-2018 HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 Gene3D G3DSA:1.10.8.60 8 237 3.3E-105 T 12-10-2018 HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 SUPERFAMILY SSF52540 31 224 1.07E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 2.0E-141 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 Pfam PF13177 DNA polymerase III, delta subunit 20 178 1.6E-45 T 12-10-2018 HW35_10090 bdf94dcae0bdaa39a4e15875afa5a09d 562 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 363 3.1E-12 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 2.7E-26 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 2.7E-26 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.7E-26 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 2.7E-26 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.7E-26 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 Gene3D G3DSA:2.40.500.20 91 202 1.0E-53 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 SUPERFAMILY SSF46609 1 91 9.03E-37 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 90 6.5E-32 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 PIRSF PIRSF000349 1 202 1.3E-87 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 8.9E-45 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 SUPERFAMILY SSF54719 92 201 4.45E-50 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 Gene3D G3DSA:1.10.287.990 20 90 2.7E-31 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_04325 fd9d6822f94814d113fccf94756e5b3e 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 SMART SM00840 353 416 2.5E-18 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 Gene3D G3DSA:3.40.50.620 1 305 2.1E-137 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 39.733 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 SUPERFAMILY SSF47323 340 464 6.21E-37 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.5E-29 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.5E-29 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.5E-29 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.5E-29 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 Gene3D G3DSA:1.20.120.1910 306 465 2.5E-38 T 12-10-2018 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 SUPERFAMILY SSF52374 4 311 1.13E-104 T 12-10-2018 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 464 2.3E-193 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 Pfam PF09190 DALR domain 353 413 4.2E-17 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HW35_10615 8f898eef6679f78a0209c9c9fe0714dc 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 8.9E-140 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 HW35_05130 8ff44758fb4dfaf5033b48622c7470b5 354 Pfam PF00437 Type II/IV secretion system protein 18 274 1.1E-40 T 12-10-2018 IPR001482 Type II/IV secretion system protein HW35_05130 8ff44758fb4dfaf5033b48622c7470b5 354 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 199 213 - T 12-10-2018 IPR001482 Type II/IV secretion system protein HW35_05130 8ff44758fb4dfaf5033b48622c7470b5 354 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 9 344 1.5E-144 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 HW35_05130 8ff44758fb4dfaf5033b48622c7470b5 354 SMART SM00382 128 253 3.6E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_05130 8ff44758fb4dfaf5033b48622c7470b5 354 SUPERFAMILY SSF52540 8 342 2.59E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05130 8ff44758fb4dfaf5033b48622c7470b5 354 Gene3D G3DSA:3.30.450.90 2 106 5.3E-36 T 12-10-2018 HW35_05130 8ff44758fb4dfaf5033b48622c7470b5 354 Gene3D G3DSA:3.40.50.300 107 353 2.7E-95 T 12-10-2018 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 SUPERFAMILY SSF47807 173 286 3.74E-33 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 SUPERFAMILY SSF53098 304 468 1.67E-41 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 ProSitePatterns PS00447 DNA polymerase family A signature. 704 723 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 Pfam PF00476 DNA polymerase family A 500 875 7.2E-162 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 Gene3D G3DSA:1.10.150.20 659 802 4.5E-111 T 12-10-2018 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 Gene3D G3DSA:1.10.150.20 175 248 1.7E-99 T 12-10-2018 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 SUPERFAMILY SSF56672 472 878 5.67E-161 T 12-10-2018 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 171 8.9E-54 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 TIGRFAM TIGR00593 pola: DNA polymerase I 6 878 0.0 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 650 673 1.3E-81 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 680 693 1.3E-81 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 704 729 1.3E-81 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 763 774 1.3E-81 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 795 811 1.3E-81 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 604 626 1.3E-81 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 825 838 1.3E-81 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 627 642 1.3E-81 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 741 752 1.3E-81 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 Gene3D G3DSA:3.40.50.1010 6 279 1.7E-99 T 12-10-2018 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 SMART SM00482 635 842 1.2E-124 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 Gene3D G3DSA:3.30.70.370 613 874 4.5E-111 T 12-10-2018 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 SMART SM00475 4 263 7.6E-151 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 SUPERFAMILY SSF88723 3 171 2.68E-56 T 12-10-2018 IPR029060 PIN-like domain superfamily HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 SMART SM00474 302 468 5.6E-14 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 SMART SM00279 174 209 9.6E-19 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 173 265 1.3E-34 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 Gene3D G3DSA:3.30.420.10 299 492 4.3E-62 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_05630 904feacf4bed10b1ab38894c1858c3fd 878 Gene3D G3DSA:1.20.1060.10 493 607 1.8E-44 T 12-10-2018 HW35_06840 4bdc4be3bcdd5073ef5222de8d17bb87 387 Gene3D G3DSA:3.40.640.10 67 290 7.3E-152 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_06840 4bdc4be3bcdd5073ef5222de8d17bb87 387 Pfam PF00155 Aminotransferase class I and II 40 374 6.8E-42 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HW35_06840 4bdc4be3bcdd5073ef5222de8d17bb87 387 Gene3D G3DSA:3.90.1150.10 12 382 7.3E-152 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_06840 4bdc4be3bcdd5073ef5222de8d17bb87 387 SUPERFAMILY SSF53383 4 386 1.17E-102 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_06840 4bdc4be3bcdd5073ef5222de8d17bb87 387 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 386 4.6E-152 T 12-10-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 PRINTS PR00046 Major sigma-70 factor signature 237 248 2.7E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 PRINTS PR00046 Major sigma-70 factor signature 54 67 2.7E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 PRINTS PR00046 Major sigma-70 factor signature 205 217 2.7E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 PRINTS PR00046 Major sigma-70 factor signature 78 86 2.7E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 PRINTS PR00046 Major sigma-70 factor signature 222 237 2.7E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 Pfam PF04542 Sigma-70 region 2 26 99 1.5E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 Gene3D G3DSA:1.20.140.160 98 255 4.3E-43 T 12-10-2018 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 Pfam PF04545 Sigma-70, region 4 201 250 2.6E-16 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 PIRSF PIRSF000770 4 260 9.7E-40 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 SUPERFAMILY SSF88946 8 99 1.38E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 SUPERFAMILY SSF88659 166 257 5.42E-21 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 SUPERFAMILY SSF88659 100 179 1.0E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 Gene3D G3DSA:1.10.1740.10 12 97 5.2E-22 T 12-10-2018 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 252 3.0E-33 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 26 252 4.4E-72 T 12-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 222 248 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_00550 5c73faaf4dacde04c0442871f3e13454 263 Pfam PF04539 Sigma-70 region 3 106 167 1.7E-10 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 HW35_11755 a4d65b7821195d4a5a3335a54336d320 105 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 1.8E-49 T 12-10-2018 IPR013368 TrpR homologue YerC/YecD HW35_11755 a4d65b7821195d4a5a3335a54336d320 105 PIRSF PIRSF012508 1 100 3.1E-49 T 12-10-2018 IPR013368 TrpR homologue YerC/YecD HW35_11755 a4d65b7821195d4a5a3335a54336d320 105 Gene3D G3DSA:1.10.1270.10 2 104 3.5E-40 T 12-10-2018 IPR038116 TrpR-like superfamily HW35_11755 a4d65b7821195d4a5a3335a54336d320 105 Pfam PF01371 Trp repressor protein 10 93 2.4E-34 T 12-10-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 HW35_11755 a4d65b7821195d4a5a3335a54336d320 105 SUPERFAMILY SSF48295 3 95 1.78E-33 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HW35_17205 7fc91f34d40f76092beedf644bcfd122 442 Pfam PF00665 Integrase core domain 280 395 1.6E-21 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_17205 7fc91f34d40f76092beedf644bcfd122 442 Gene3D G3DSA:3.30.420.10 274 439 1.8E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_17205 7fc91f34d40f76092beedf644bcfd122 442 Pfam PF13276 HTH-like domain 195 250 1.3E-12 T 12-10-2018 IPR025948 HTH-like domain HW35_17205 7fc91f34d40f76092beedf644bcfd122 442 SUPERFAMILY SSF53098 272 437 1.67E-28 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_08915 196ece37595884e3085a9f6ff295f11a 251 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 51 64 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site HW35_08915 196ece37595884e3085a9f6ff295f11a 251 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 32 242 3.0E-59 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_08915 196ece37595884e3085a9f6ff295f11a 251 SUPERFAMILY SSF53850 3 244 1.65E-61 T 12-10-2018 HW35_08915 196ece37595884e3085a9f6ff295f11a 251 SMART SM00079 28 242 4.7E-5 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HW35_08915 196ece37595884e3085a9f6ff295f11a 251 Gene3D G3DSA:3.40.190.10 26 240 1.5E-60 T 12-10-2018 HW35_08915 196ece37595884e3085a9f6ff295f11a 251 SMART SM00062 28 243 1.1E-55 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_08915 196ece37595884e3085a9f6ff295f11a 251 Gene3D G3DSA:3.40.190.10 112 205 1.5E-60 T 12-10-2018 HW35_13695 4dd5810643c5f0b633b692263436f4b1 74 Hamap MF_00829 UPF0435 protein . 6 73 21.567 T 12-10-2018 IPR009507 Protein of unknown function UPF0435 HW35_13695 4dd5810643c5f0b633b692263436f4b1 74 Pfam PF06569 Protein of unknown function (DUF1128) 3 73 2.6E-34 T 12-10-2018 IPR009507 Protein of unknown function UPF0435 HW35_15200 41dcf64390e3da09059f5be955b98b90 338 Gene3D G3DSA:3.20.20.70 4 338 1.7E-108 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_15200 41dcf64390e3da09059f5be955b98b90 338 SMART SM00729 15 223 7.9E-16 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HW35_15200 41dcf64390e3da09059f5be955b98b90 338 Pfam PF06463 Molybdenum Cofactor Synthesis C 191 317 1.3E-37 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_15200 41dcf64390e3da09059f5be955b98b90 338 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 6 338 41.139 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_15200 41dcf64390e3da09059f5be955b98b90 338 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 7 338 6.6E-122 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_15200 41dcf64390e3da09059f5be955b98b90 338 Pfam PF13353 4Fe-4S single cluster domain 18 129 1.8E-6 T 12-10-2018 HW35_15200 41dcf64390e3da09059f5be955b98b90 338 SUPERFAMILY SSF102114 8 307 2.62E-80 T 12-10-2018 HW35_15200 41dcf64390e3da09059f5be955b98b90 338 Pfam PF04055 Radical SAM superfamily 19 184 9.8E-31 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_15200 41dcf64390e3da09059f5be955b98b90 338 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 21 32 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_09405 1ed50576a787525a49384127ecaa236c 166 Pfam PF09671 Spore coat protein (Spore_GerQ) 75 150 1.3E-37 T 12-10-2018 IPR014099 Spore coat protein GerQ HW35_09405 1ed50576a787525a49384127ecaa236c 166 PIRSF PIRSF038931 1 166 1.6E-50 T 12-10-2018 IPR014099 Spore coat protein GerQ HW35_09405 1ed50576a787525a49384127ecaa236c 166 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 73 154 6.4E-39 T 12-10-2018 IPR014099 Spore coat protein GerQ HW35_10245 825a25f5271561bc46b4c57f5c2afc80 272 Gene3D G3DSA:3.40.50.2020 74 272 7.9E-63 T 12-10-2018 HW35_10245 825a25f5271561bc46b4c57f5c2afc80 272 Gene3D G3DSA:1.10.10.10 1 72 5.5E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_10245 825a25f5271561bc46b4c57f5c2afc80 272 Pfam PF00156 Phosphoribosyl transferase domain 108 262 5.5E-27 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HW35_10245 825a25f5271561bc46b4c57f5c2afc80 272 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 74 7.0E-24 T 12-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 HW35_10245 825a25f5271561bc46b4c57f5c2afc80 272 Pfam PF09182 Bacterial purine repressor, N-terminal 4 72 2.1E-31 T 12-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 HW35_10245 825a25f5271561bc46b4c57f5c2afc80 272 SUPERFAMILY SSF46785 2 72 7.21E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_10245 825a25f5271561bc46b4c57f5c2afc80 272 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 270 3.2E-124 T 12-10-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 HW35_10245 825a25f5271561bc46b4c57f5c2afc80 272 SUPERFAMILY SSF53271 94 256 2.63E-41 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_15890 d3ca98ea418f668f596e81d98743f922 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 4.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_15890 d3ca98ea418f668f596e81d98743f922 292 SUPERFAMILY SSF46785 6 112 3.25E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_15890 d3ca98ea418f668f596e81d98743f922 292 SUPERFAMILY SSF53850 88 291 2.05E-31 T 12-10-2018 HW35_15890 d3ca98ea418f668f596e81d98743f922 292 Pfam PF03466 LysR substrate binding domain 88 288 6.5E-34 T 12-10-2018 IPR005119 LysR, substrate-binding HW35_15890 d3ca98ea418f668f596e81d98743f922 292 Gene3D G3DSA:1.10.10.10 2 82 1.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_15890 d3ca98ea418f668f596e81d98743f922 292 Gene3D G3DSA:3.40.190.290 83 288 4.2E-68 T 12-10-2018 HW35_15890 d3ca98ea418f668f596e81d98743f922 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_15890 d3ca98ea418f668f596e81d98743f922 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_15890 d3ca98ea418f668f596e81d98743f922 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 Pfam PF07085 DRTGG domain 78 180 7.5E-31 T 12-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 SMART SM00116 202 250 1.1 T 12-10-2018 IPR000644 CBS domain HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 SMART SM00116 261 309 0.027 T 12-10-2018 IPR000644 CBS domain HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 SUPERFAMILY SSF54637 336 439 2.35E-20 T 12-10-2018 IPR029069 HotDog domain superfamily HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 Pfam PF03061 Thioesterase superfamily 354 426 1.6E-11 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 SUPERFAMILY SSF75138 74 187 6.93E-29 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 Gene3D G3DSA:1.10.10.10 7 71 1.2E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 Pfam PF00571 CBS domain 255 309 4.1E-7 T 12-10-2018 IPR000644 CBS domain HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 Pfam PF00571 CBS domain 221 246 0.002 T 12-10-2018 IPR000644 CBS domain HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 Gene3D G3DSA:3.40.1390.20 72 180 9.0E-26 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 Gene3D G3DSA:3.10.129.10 325 439 1.7E-12 T 12-10-2018 HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 SUPERFAMILY SSF54631 184 309 2.27E-28 T 12-10-2018 HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 60 6.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 SUPERFAMILY SSF46785 7 56 4.93E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_05740 fe36c52cd14af50f90976ae77b800b51 440 Gene3D G3DSA:3.10.580.10 189 316 2.0E-22 T 12-10-2018 HW35_14005 b9d5a657f04e22a2e6ce974c828ee6b2 632 Pfam PF09709 CRISPR-associated protein (Cas_Csd1) 7 618 2.6E-141 T 12-10-2018 IPR010144 CRISPR-associated protein, Csd1-type HW35_14005 b9d5a657f04e22a2e6ce974c828ee6b2 632 TIGRFAM TIGR01863 cas_Csd1: CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG 18 623 4.6E-146 T 12-10-2018 IPR010144 CRISPR-associated protein, Csd1-type HW35_16185 577ad930f78fbb803330d59fbb19745b 186 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 181 8.9E-56 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 HW35_16185 577ad930f78fbb803330d59fbb19745b 186 PIRSF PIRSF004553 1 183 8.0E-52 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 HW35_16185 577ad930f78fbb803330d59fbb19745b 186 Gene3D G3DSA:3.40.50.150 1 183 7.1E-60 T 12-10-2018 HW35_16185 577ad930f78fbb803330d59fbb19745b 186 SUPERFAMILY SSF53335 1 180 8.81E-53 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_16185 577ad930f78fbb803330d59fbb19745b 186 Pfam PF03602 Conserved hypothetical protein 95 1 180 3.7E-61 T 12-10-2018 HW35_16185 577ad930f78fbb803330d59fbb19745b 186 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 Pfam PF05697 Bacterial trigger factor protein (TF) 1 147 1.6E-43 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 Hamap MF_00303 Trigger factor [tig]. 1 428 23.9 T 12-10-2018 IPR005215 Trigger factor GO:0015031 HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 Gene3D G3DSA:3.10.50.40 154 251 3.2E-97 T 12-10-2018 HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 162 242 5.4E-15 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 SUPERFAMILY SSF109998 253 428 1.44E-44 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 SUPERFAMILY SSF54534 96 246 3.14E-36 T 12-10-2018 HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 Gene3D G3DSA:1.10.3120.10 120 427 3.2E-97 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 PIRSF PIRSF003095 1 428 7.0E-142 T 12-10-2018 IPR005215 Trigger factor GO:0015031 HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 Gene3D G3DSA:3.30.70.1050 1 119 1.8E-30 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 TIGRFAM TIGR00115 tig: trigger factor 13 424 7.6E-144 T 12-10-2018 IPR005215 Trigger factor GO:0015031 HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 SUPERFAMILY SSF102735 1 132 7.32E-38 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 HW35_05270 1f5fc68ea885a5820dbe40aa522e9a31 428 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 267 425 7.2E-47 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 HW35_15610 c7f8c6ae3b41e984de218ad0a2cb0c0e 579 SMART SM00382 188 324 2.0E-23 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_15610 c7f8c6ae3b41e984de218ad0a2cb0c0e 579 Gene3D G3DSA:1.20.58.760 406 578 1.1E-42 T 12-10-2018 HW35_15610 c7f8c6ae3b41e984de218ad0a2cb0c0e 579 Gene3D G3DSA:3.40.50.300 145 323 2.1E-58 T 12-10-2018 HW35_15610 c7f8c6ae3b41e984de218ad0a2cb0c0e 579 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 321 2.5E-39 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_15610 c7f8c6ae3b41e984de218ad0a2cb0c0e 579 SUPERFAMILY SSF52540 150 399 3.27E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15610 c7f8c6ae3b41e984de218ad0a2cb0c0e 579 Pfam PF01434 Peptidase family M41 385 521 5.7E-30 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 HW35_15610 c7f8c6ae3b41e984de218ad0a2cb0c0e 579 Gene3D G3DSA:1.10.8.60 324 402 8.2E-19 T 12-10-2018 HW35_15610 c7f8c6ae3b41e984de218ad0a2cb0c0e 579 SUPERFAMILY SSF140990 406 569 1.44E-38 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 HW35_15315 c8f885f80d1e77ad5c0eb3d2e84fbc36 342 Gene3D G3DSA:1.10.3720.10 130 342 1.0E-24 T 12-10-2018 IPR035906 MetI-like superfamily HW35_15315 c8f885f80d1e77ad5c0eb3d2e84fbc36 342 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 84 2.4E-17 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HW35_15315 c8f885f80d1e77ad5c0eb3d2e84fbc36 342 SUPERFAMILY SSF161098 135 326 7.59E-27 T 12-10-2018 IPR035906 MetI-like superfamily HW35_15315 c8f885f80d1e77ad5c0eb3d2e84fbc36 342 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 158 341 3.9E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_04600 4a7cce9532064e67f9e83665b1c0fe85 775 SUPERFAMILY SSF56281 509 763 6.09E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_04600 4a7cce9532064e67f9e83665b1c0fe85 775 Pfam PF03772 Competence protein 213 476 1.9E-63 T 12-10-2018 IPR004477 ComEC/Rec2-related protein HW35_04600 4a7cce9532064e67f9e83665b1c0fe85 775 Pfam PF13567 Domain of unknown function (DUF4131) 17 171 1.9E-14 T 12-10-2018 IPR025405 Domain of unknown function DUF4131 HW35_04600 4a7cce9532064e67f9e83665b1c0fe85 775 Pfam PF00753 Metallo-beta-lactamase superfamily 515 726 1.6E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_04600 4a7cce9532064e67f9e83665b1c0fe85 775 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 234 406 7.8E-38 T 12-10-2018 IPR004477 ComEC/Rec2-related protein HW35_04600 4a7cce9532064e67f9e83665b1c0fe85 775 Gene3D G3DSA:3.60.15.10 508 768 1.0E-69 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_04600 4a7cce9532064e67f9e83665b1c0fe85 775 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 98 757 2.0E-110 T 12-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 HW35_04600 4a7cce9532064e67f9e83665b1c0fe85 775 SMART SM00849 517 728 6.0E-6 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_09275 929659fc4c90419d18f46b28bb67341a 376 SUPERFAMILY SSF47203 226 376 2.74E-60 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 HW35_09275 929659fc4c90419d18f46b28bb67341a 376 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HW35_09275 929659fc4c90419d18f46b28bb67341a 376 Gene3D G3DSA:1.20.140.10 234 376 2.5E-57 T 12-10-2018 HW35_09275 929659fc4c90419d18f46b28bb67341a 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.8E-41 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 HW35_09275 929659fc4c90419d18f46b28bb67341a 376 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 1.0E-27 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 HW35_09275 929659fc4c90419d18f46b28bb67341a 376 SUPERFAMILY SSF56645 2 239 8.64E-90 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 HW35_09275 929659fc4c90419d18f46b28bb67341a 376 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 375 3.1E-53 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HW35_09275 929659fc4c90419d18f46b28bb67341a 376 Gene3D G3DSA:1.10.540.10 1 119 1.5E-46 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 HW35_09275 929659fc4c90419d18f46b28bb67341a 376 Gene3D G3DSA:2.40.110.10 120 233 1.9E-47 T 12-10-2018 HW35_09275 929659fc4c90419d18f46b28bb67341a 376 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HW35_09275 929659fc4c90419d18f46b28bb67341a 376 PIRSF PIRSF016578 4 366 2.1E-24 T 12-10-2018 HW35_11855 eeee2cc082f8a7f726c28030a0af915e 313 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 127 9.0E-38 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 HW35_11855 eeee2cc082f8a7f726c28030a0af915e 313 SMART SM00046 3 131 3.1E-14 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 HW35_11855 eeee2cc082f8a7f726c28030a0af915e 313 Gene3D G3DSA:3.40.50.10330 6 124 2.1E-95 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 HW35_11855 eeee2cc082f8a7f726c28030a0af915e 313 SUPERFAMILY SSF111331 1 293 9.94E-88 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily HW35_11855 eeee2cc082f8a7f726c28030a0af915e 313 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 292 1.0E-111 T 12-10-2018 IPR005218 Diacylglycerol/lipid kinase HW35_11855 eeee2cc082f8a7f726c28030a0af915e 313 Gene3D G3DSA:2.60.200.40 125 279 2.1E-95 T 12-10-2018 HW35_04745 03c83e89efccb2630de11c85b7e70f13 309 Pfam PF01136 Peptidase family U32 75 306 2.0E-68 T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 HW35_15660 3c3c4d3175095de802ece0b074290d8d 337 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 13 196 3.8E-34 T 12-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 HW35_15660 3c3c4d3175095de802ece0b074290d8d 337 Gene3D G3DSA:3.30.70.3270 242 332 2.8E-12 T 12-10-2018 HW35_15660 3c3c4d3175095de802ece0b074290d8d 337 Gene3D G3DSA:3.40.920.10 11 198 1.7E-51 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HW35_15660 3c3c4d3175095de802ece0b074290d8d 337 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 21 192 3.8E-29 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HW35_15660 3c3c4d3175095de802ece0b074290d8d 337 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 295 306 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_15660 3c3c4d3175095de802ece0b074290d8d 337 SUPERFAMILY SSF54862 247 326 8.37E-18 T 12-10-2018 HW35_15660 3c3c4d3175095de802ece0b074290d8d 337 Pfam PF12838 4Fe-4S dicluster domain 255 309 6.0E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HW35_15660 3c3c4d3175095de802ece0b074290d8d 337 SUPERFAMILY SSF53323 12 196 1.26E-36 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HW35_02425 f7c644c9f49eb938a8803bf9eee603ec 217 SUPERFAMILY SSF51735 3 136 1.02E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_02425 f7c644c9f49eb938a8803bf9eee603ec 217 Pfam PF02254 TrkA-N domain 5 120 5.3E-29 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HW35_02425 f7c644c9f49eb938a8803bf9eee603ec 217 SUPERFAMILY SSF116726 131 216 8.24E-21 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_02425 f7c644c9f49eb938a8803bf9eee603ec 217 Gene3D G3DSA:3.40.50.720 1 137 6.4E-38 T 12-10-2018 HW35_02425 f7c644c9f49eb938a8803bf9eee603ec 217 Pfam PF02080 TrkA-C domain 151 216 1.4E-13 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HW35_02425 f7c644c9f49eb938a8803bf9eee603ec 217 Gene3D G3DSA:3.30.70.1450 138 215 9.7E-27 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 SUPERFAMILY SSF51735 1 158 6.2E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 Gene3D G3DSA:3.40.50.720 4 340 2.9E-152 T 12-10-2018 HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 Gene3D G3DSA:3.30.360.10 136 343 2.9E-152 T 12-10-2018 HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 Pfam PF00742 Homoserine dehydrogenase 137 315 1.8E-66 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 Gene3D G3DSA:3.30.70.260 344 417 2.9E-152 T 12-10-2018 HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 SUPERFAMILY SSF55021 348 420 2.57E-12 T 12-10-2018 HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 PIRSF PIRSF000098 1 428 1.0E-171 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 1.3E-22 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 SUPERFAMILY SSF55347 137 302 5.23E-54 T 12-10-2018 HW35_06600 603bedfcc9001d9c52103f64530e4cd8 428 Pfam PF01842 ACT domain 349 414 6.3E-12 T 12-10-2018 IPR002912 ACT domain HW35_15145 0eaddf1e0e7bf814ae6c969fb5f4d29a 287 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 280 1.7E-95 T 12-10-2018 IPR003797 DegV HW35_15145 0eaddf1e0e7bf814ae6c969fb5f4d29a 287 Gene3D G3DSA:3.40.50.10170 1 152 9.8E-46 T 12-10-2018 HW35_15145 0eaddf1e0e7bf814ae6c969fb5f4d29a 287 SUPERFAMILY SSF82549 1 283 2.88E-92 T 12-10-2018 HW35_15145 0eaddf1e0e7bf814ae6c969fb5f4d29a 287 Gene3D G3DSA:3.30.1180.10 156 285 5.0E-50 T 12-10-2018 HW35_15145 0eaddf1e0e7bf814ae6c969fb5f4d29a 287 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 282 6.4E-89 T 12-10-2018 IPR003797 DegV HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 SUPERFAMILY SSF52540 369 629 8.4E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 Pfam PF00271 Helicase conserved C-terminal domain 453 572 6.2E-21 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 Pfam PF00270 DEAD/DEAH box helicase 259 415 4.4E-18 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 SUPERFAMILY SSF50249 3 170 4.28E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 SUPERFAMILY SSF52540 174 436 8.17E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 27 648 7.3E-250 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 Gene3D G3DSA:3.40.50.300 441 613 5.1E-59 T 12-10-2018 HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 SMART SM00487 253 443 1.4E-32 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 Gene3D G3DSA:2.40.50.140 46 139 1.5E-10 T 12-10-2018 HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 Gene3D G3DSA:3.40.50.300 195 434 1.1E-87 T 12-10-2018 HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 Pfam PF17191 RecG wedge domain 9 165 5.1E-17 T 12-10-2018 IPR033454 RecG, wedge domain HW35_16625 ed52728e79bc78b304b5ee82688c6bf0 682 SMART SM00490 492 573 4.4E-23 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_12010 dd2e2e9d9b93036cef77fcd798fc2437 316 SUPERFAMILY SSF81345 4 311 3.79E-57 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_12010 dd2e2e9d9b93036cef77fcd798fc2437 316 Pfam PF01032 FecCD transport family 36 311 5.5E-55 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 HW35_12010 dd2e2e9d9b93036cef77fcd798fc2437 316 Gene3D G3DSA:1.10.3470.10 3 316 2.2E-56 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_09765 5ca50524121326d525d76e8c7d82d1b8 511 Gene3D G3DSA:1.20.1260.30 5 151 2.2E-38 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily HW35_09765 5ca50524121326d525d76e8c7d82d1b8 511 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 207 221 7.7E-21 T 12-10-2018 HW35_09765 5ca50524121326d525d76e8c7d82d1b8 511 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 275 287 7.7E-21 T 12-10-2018 HW35_09765 5ca50524121326d525d76e8c7d82d1b8 511 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 184 200 7.7E-21 T 12-10-2018 HW35_09765 5ca50524121326d525d76e8c7d82d1b8 511 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 309 333 7.7E-21 T 12-10-2018 HW35_09765 5ca50524121326d525d76e8c7d82d1b8 511 Pfam PF12161 HsdM N-terminal domain 9 148 6.2E-26 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain HW35_09765 5ca50524121326d525d76e8c7d82d1b8 511 Pfam PF02384 N-6 DNA Methylase 161 473 3.1E-94 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HW35_09765 5ca50524121326d525d76e8c7d82d1b8 511 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 278 284 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HW35_09765 5ca50524121326d525d76e8c7d82d1b8 511 SUPERFAMILY SSF53335 7 509 5.99E-125 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_09765 5ca50524121326d525d76e8c7d82d1b8 511 Gene3D G3DSA:3.40.50.150 161 457 8.8E-99 T 12-10-2018 HW35_15885 c5057f8e20b7387ce4ea864c42229fc4 497 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 484 1.4E-73 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 HW35_15885 c5057f8e20b7387ce4ea864c42229fc4 497 SUPERFAMILY SSF103473 10 490 6.93E-70 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_15885 c5057f8e20b7387ce4ea864c42229fc4 497 Pfam PF07690 Major Facilitator Superfamily 17 409 6.9E-54 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_15885 c5057f8e20b7387ce4ea864c42229fc4 497 Gene3D G3DSA:1.20.1720.10 13 220 6.0E-58 T 12-10-2018 HW35_15885 c5057f8e20b7387ce4ea864c42229fc4 497 Gene3D G3DSA:1.20.1250.20 265 495 7.8E-22 T 12-10-2018 HW35_15885 c5057f8e20b7387ce4ea864c42229fc4 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 75 97 1.3E-6 T 12-10-2018 HW35_15885 c5057f8e20b7387ce4ea864c42229fc4 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 201 219 1.3E-6 T 12-10-2018 HW35_15885 c5057f8e20b7387ce4ea864c42229fc4 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 1.3E-6 T 12-10-2018 HW35_15885 c5057f8e20b7387ce4ea864c42229fc4 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 1.3E-6 T 12-10-2018 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 SUPERFAMILY SSF55874 12 224 2.23E-69 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR01159 DNA gyrase subunit B signature 614 630 2.5E-59 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR01159 DNA gyrase subunit B signature 598 610 2.5E-59 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR01159 DNA gyrase subunit B signature 479 488 2.5E-59 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR01159 DNA gyrase subunit B signature 367 381 2.5E-59 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR01159 DNA gyrase subunit B signature 226 248 2.5E-59 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR01159 DNA gyrase subunit B signature 381 401 2.5E-59 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR01159 DNA gyrase subunit B signature 13 23 2.5E-59 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR01159 DNA gyrase subunit B signature 202 215 2.5E-59 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR01159 DNA gyrase subunit B signature 317 333 2.5E-59 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR01159 DNA gyrase subunit B signature 187 202 2.5E-59 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 Gene3D G3DSA:3.40.50.670 415 647 2.9E-103 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 Gene3D G3DSA:3.30.565.10 11 225 5.8E-87 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 Pfam PF00204 DNA gyrase B 227 397 2.5E-58 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR00418 DNA topoisomerase II family signature 577 593 1.1E-69 T 12-10-2018 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR00418 DNA topoisomerase II family signature 513 530 1.1E-69 T 12-10-2018 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR00418 DNA topoisomerase II family signature 42 57 1.1E-69 T 12-10-2018 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR00418 DNA topoisomerase II family signature 119 133 1.1E-69 T 12-10-2018 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR00418 DNA topoisomerase II family signature 533 545 1.1E-69 T 12-10-2018 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR00418 DNA topoisomerase II family signature 77 90 1.1E-69 T 12-10-2018 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR00418 DNA topoisomerase II family signature 429 443 1.1E-69 T 12-10-2018 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR00418 DNA topoisomerase II family signature 495 511 1.1E-69 T 12-10-2018 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 PRINTS PR00418 DNA topoisomerase II family signature 273 286 1.1E-69 T 12-10-2018 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 11 643 48.809 T 12-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 ProSitePatterns PS00177 DNA topoisomerase II signature. 431 439 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 SMART SM00387 38 182 1.0E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 SUPERFAMILY SSF54211 227 398 1.27E-54 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 SUPERFAMILY SSF56719 403 638 4.18E-87 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 12 645 0.0 T 12-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 Pfam PF01751 Toprim domain 428 528 9.8E-18 T 12-10-2018 IPR006171 TOPRIM domain HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 38 180 9.6E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 Gene3D G3DSA:3.30.230.10 226 407 1.8E-73 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 574 634 2.8E-30 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_01025 a3660f1f05dada4c9cfb0b0b556cb953 662 SMART SM00433 42 638 0.0 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_09010 1f710f8cf7921c74c6409fad4974583e 299 Gene3D G3DSA:3.30.2030.10 82 224 1.1E-35 T 12-10-2018 HW35_09010 1f710f8cf7921c74c6409fad4974583e 299 SUPERFAMILY SSF143842 84 297 8.5E-47 T 12-10-2018 IPR036209 YwmB-like superfamily HW35_09010 1f710f8cf7921c74c6409fad4974583e 299 Gene3D G3DSA:3.30.360.40 225 299 1.4E-25 T 12-10-2018 HW35_09010 1f710f8cf7921c74c6409fad4974583e 299 Pfam PF08680 TATA-box binding 100 299 1.1E-48 T 12-10-2018 IPR014794 TATA-box binding HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 PRINTS PR00819 CbxX/CfqX superfamily signature 212 231 2.0E-59 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 PRINTS PR00819 CbxX/CfqX superfamily signature 272 284 2.0E-59 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 PRINTS PR00819 CbxX/CfqX superfamily signature 144 163 2.0E-59 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 PRINTS PR00819 CbxX/CfqX superfamily signature 52 66 2.0E-59 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 PRINTS PR00819 CbxX/CfqX superfamily signature 92 107 2.0E-59 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 PRINTS PR00819 CbxX/CfqX superfamily signature 195 212 2.0E-59 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 PRINTS PR00819 CbxX/CfqX superfamily signature 130 144 2.0E-59 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 PRINTS PR00819 CbxX/CfqX superfamily signature 174 186 2.0E-59 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 SMART SM00382 89 227 1.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 SUPERFAMILY SSF52540 47 308 3.73E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 Gene3D G3DSA:3.40.50.300 39 224 8.1E-58 T 12-10-2018 HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 49 310 2.8E-135 T 12-10-2018 IPR014232 Sporulation stage V, protein K HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 224 1.4E-19 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_17150 a6b82d5c266656437b79b0b8f5d9734d 315 Gene3D G3DSA:1.10.8.60 225 314 2.8E-19 T 12-10-2018 HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 Pfam PF03144 Elongation factor Tu domain 2 187 253 1.7E-11 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 SUPERFAMILY SSF50465 260 355 7.48E-27 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 2 618 6.6E-108 T 12-10-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 SUPERFAMILY SSF52540 2 188 3.19E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 Pfam PF09106 Elongation factor SelB, winged helix 436 489 1.3E-7 T 12-10-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 SUPERFAMILY SSF50447 167 256 8.25E-24 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 Gene3D G3DSA:2.40.30.10 168 288 1.0E-31 T 12-10-2018 HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 SUPERFAMILY SSF46785 429 496 6.26E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 Pfam PF09107 Elongation factor SelB, winged helix 577 616 5.3E-15 T 12-10-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 127 3.4E-14 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 SUPERFAMILY SSF46785 577 616 2.1E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 Gene3D G3DSA:3.40.50.300 1 164 9.6E-50 T 12-10-2018 HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 Gene3D G3DSA:1.10.10.2770 429 560 5.8E-19 T 12-10-2018 HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 Gene3D G3DSA:1.10.10.10 562 617 1.4E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_17555 78ae72d8b5db9fd212e572af2e46eab6 618 Pfam PF00009 Elongation factor Tu GTP binding domain 2 161 2.1E-33 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 SUPERFAMILY SSF55729 155 295 4.32E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 Pfam PF12802 MarR family 35 93 4.0E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 Gene3D G3DSA:1.10.10.10 4 141 2.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 Pfam PF00583 Acetyltransferase (GNAT) family 197 286 5.5E-14 T 12-10-2018 IPR000182 GNAT domain HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 SUPERFAMILY SSF46785 15 146 4.18E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 2.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 2.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 2.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 2.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 SMART SM00347 29 129 1.7E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_13890 f5e27daede7eec9ea3380de971e0bdb1 310 Gene3D G3DSA:3.40.630.30 171 299 3.1E-25 T 12-10-2018 HW35_14630 dcb192862be339c2f98f71b400059c0d 296 Gene3D G3DSA:3.40.33.10 22 295 7.4E-64 T 12-10-2018 IPR035940 CAP superfamily HW35_14630 dcb192862be339c2f98f71b400059c0d 296 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 174 295 2.3E-55 T 12-10-2018 IPR014258 CAP domain, YkwD-like HW35_14630 dcb192862be339c2f98f71b400059c0d 296 Pfam PF00188 Cysteine-rich secretory protein family 181 291 2.8E-23 T 12-10-2018 IPR014044 CAP domain HW35_14630 dcb192862be339c2f98f71b400059c0d 296 SUPERFAMILY SSF55797 173 290 6.28E-27 T 12-10-2018 IPR035940 CAP superfamily HW35_16395 05317f89ef274072e6963f605fd8cc54 259 SUPERFAMILY SSF88659 175 258 4.49E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_16395 05317f89ef274072e6963f605fd8cc54 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 257 3.5E-83 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 256 4.5E-34 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 Pfam PF04539 Sigma-70 region 3 124 173 2.1E-7 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 PRINTS PR00046 Major sigma-70 factor signature 90 98 4.0E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 PRINTS PR00046 Major sigma-70 factor signature 66 79 4.0E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 PRINTS PR00046 Major sigma-70 factor signature 227 242 4.0E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 PRINTS PR00046 Major sigma-70 factor signature 210 222 4.0E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 PRINTS PR00046 Major sigma-70 factor signature 242 253 4.0E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 1.5E-155 T 12-10-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 Gene3D G3DSA:1.20.120.1810 3 110 3.8E-27 T 12-10-2018 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 Pfam PF04542 Sigma-70 region 2 42 110 4.0E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 Pfam PF04545 Sigma-70, region 4 207 253 9.0E-13 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 PIRSF PIRSF000770 16 259 1.2E-33 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 SUPERFAMILY SSF88946 6 110 7.59E-34 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 Gene3D G3DSA:1.20.140.160 113 259 1.5E-25 T 12-10-2018 HW35_16395 05317f89ef274072e6963f605fd8cc54 259 SUPERFAMILY SSF88659 114 190 7.41E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 544 663 5.2E-47 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 SUPERFAMILY SSF51261 535 683 4.01E-55 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 64 355 4.6E-88 T 12-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 506 8.9E-248 T 12-10-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0016021|GO:1904659 HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 SUPERFAMILY SSF55604 431 504 2.88E-22 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 605 617 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 444 461 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 Gene3D G3DSA:3.30.1360.60 427 507 1.1E-29 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 Pfam PF02378 Phosphotransferase system, EIIC 14 344 7.3E-91 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 542 664 1.2E-52 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 Pfam PF00367 phosphotransferase system, EIIB 434 466 8.9E-15 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 Gene3D G3DSA:2.70.70.10 530 690 1.5E-63 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_11645 2883a025be41d701c44d51f7ab2013bd 690 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 403 490 2.1E-26 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HW35_12710 6e7aec89365b9705fab53fec1ebe5f96 226 SUPERFAMILY SSF52540 4 219 1.57E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12710 6e7aec89365b9705fab53fec1ebe5f96 226 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_12710 6e7aec89365b9705fab53fec1ebe5f96 226 Gene3D G3DSA:3.40.50.300 4 224 2.2E-56 T 12-10-2018 HW35_12710 6e7aec89365b9705fab53fec1ebe5f96 226 Pfam PF00005 ABC transporter 23 169 2.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12710 6e7aec89365b9705fab53fec1ebe5f96 226 SMART SM00382 32 225 4.7E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 Gene3D G3DSA:2.40.110.10 145 249 3.7E-35 T 12-10-2018 HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 Gene3D G3DSA:1.20.140.10 251 421 1.2E-50 T 12-10-2018 HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 146 239 2.5E-22 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 377 396 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 Gene3D G3DSA:1.10.540.10 2 144 1.4E-45 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 148 160 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 SUPERFAMILY SSF47203 249 421 2.09E-44 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 142 5.1E-30 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 Gene3D G3DSA:1.20.140.10 422 593 1.9E-57 T 12-10-2018 HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 SUPERFAMILY SSF56645 23 262 1.03E-74 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 HW35_07150 e9d2ee1d063457b34c62468baa28b049 593 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 251 414 3.4E-35 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 SUPERFAMILY SSF53822 62 337 1.85E-70 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 SUPERFAMILY SSF47413 3 60 1.02E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 Gene3D G3DSA:1.10.260.40 1 60 1.7E-22 T 12-10-2018 HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 3.6E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 3.6E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 Gene3D G3DSA:3.40.50.2300 167 296 2.9E-75 T 12-10-2018 HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 Gene3D G3DSA:3.40.50.2300 76 328 2.9E-75 T 12-10-2018 HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 9.0E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 SMART SM00354 2 72 7.0E-27 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_13145 c5a6d15fdd85cee3a8d4e3d678dee298 347 Pfam PF13377 Periplasmic binding protein-like domain 176 336 2.6E-32 T 12-10-2018 HW35_00210 4ba5dc496f65817cd75793db62d37085 360 SMART SM00448 4 127 4.2E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_00210 4ba5dc496f65817cd75793db62d37085 360 SUPERFAMILY SSF52172 1 108 1.99E-29 T 12-10-2018 IPR011006 CheY-like superfamily HW35_00210 4ba5dc496f65817cd75793db62d37085 360 Gene3D G3DSA:3.40.50.2300 2 135 2.4E-31 T 12-10-2018 HW35_00210 4ba5dc496f65817cd75793db62d37085 360 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 360 33.792 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HW35_00210 4ba5dc496f65817cd75793db62d37085 360 Gene3D G3DSA:3.40.50.180 166 360 3.6E-60 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal HW35_00210 4ba5dc496f65817cd75793db62d37085 360 SUPERFAMILY SSF52738 171 359 2.22E-54 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal HW35_00210 4ba5dc496f65817cd75793db62d37085 360 Pfam PF00072 Response regulator receiver domain 6 109 1.2E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_00210 4ba5dc496f65817cd75793db62d37085 360 PIRSF PIRSF000876 1 360 6.0E-115 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HW35_00210 4ba5dc496f65817cd75793db62d37085 360 Pfam PF01339 CheB methylesterase 174 355 7.0E-55 T 12-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 Gene3D G3DSA:3.40.50.10380 1 157 8.7E-76 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 SMART SM00919 160 384 1.9E-138 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 SMART SM01274 15 148 1.9E-85 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 Pfam PF03949 Malic enzyme, NAD binding domain 162 383 1.8E-24 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 PRINTS PR00072 Malic enzyme signature 276 292 1.9E-7 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 PRINTS PR00072 Malic enzyme signature 156 172 1.9E-7 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 PRINTS PR00072 Malic enzyme signature 77 99 1.9E-7 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 PIRSF PIRSF000106 35 408 1.2E-86 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 Gene3D G3DSA:3.40.50.720 158 411 7.4E-92 T 12-10-2018 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 SUPERFAMILY SSF51735 160 404 2.22E-86 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 SUPERFAMILY SSF53223 6 158 7.91E-58 T 12-10-2018 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 Pfam PF00390 Malic enzyme, N-terminal domain 17 148 2.7E-30 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HW35_05710 880b2b29e8d0099a4ea31133111a1a4e 412 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 12-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 Pfam PF00117 Glutamine amidotransferase class-I 4 186 5.4E-55 T 12-10-2018 IPR017926 Glutamine amidotransferase HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 4.3E-87 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 2.1E-13 T 12-10-2018 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 2.1E-13 T 12-10-2018 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 2.1E-13 T 12-10-2018 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 SUPERFAMILY SSF52317 1 187 4.58E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.8E-5 T 12-10-2018 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.8E-5 T 12-10-2018 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 Gene3D G3DSA:3.40.50.880 1 188 1.7E-62 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00097 Anthranilate synthase component II signature 119 131 3.7E-35 T 12-10-2018 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00097 Anthranilate synthase component II signature 2 16 3.7E-35 T 12-10-2018 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00097 Anthranilate synthase component II signature 47 56 3.7E-35 T 12-10-2018 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00097 Anthranilate synthase component II signature 99 107 3.7E-35 T 12-10-2018 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00097 Anthranilate synthase component II signature 74 85 3.7E-35 T 12-10-2018 HW35_15570 d3f0d1efe13c06ae9dbbc371352218b1 196 PRINTS PR00097 Anthranilate synthase component II signature 164 177 3.7E-35 T 12-10-2018 HW35_03545 8499752814a790d480ad5687203d611c 183 Gene3D G3DSA:1.10.1740.10 1 71 4.1E-26 T 12-10-2018 HW35_03545 8499752814a790d480ad5687203d611c 183 Gene3D G3DSA:1.10.10.10 89 168 1.8E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_03545 8499752814a790d480ad5687203d611c 183 SUPERFAMILY SSF88659 92 167 6.17E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_03545 8499752814a790d480ad5687203d611c 183 SUPERFAMILY SSF88946 4 83 9.81E-25 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_03545 8499752814a790d480ad5687203d611c 183 Pfam PF04542 Sigma-70 region 2 8 74 7.4E-19 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_03545 8499752814a790d480ad5687203d611c 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 165 1.4E-34 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_03545 8499752814a790d480ad5687203d611c 183 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 30 61 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_03545 8499752814a790d480ad5687203d611c 183 Pfam PF08281 Sigma-70, region 4 121 161 1.8E-9 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Pfam PF01131 DNA topoisomerase 128 548 1.7E-138 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Gene3D G3DSA:3.40.50.140 1 134 2.0E-52 T 12-10-2018 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 643 56.225 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 SUPERFAMILY SSF56712 4 590 1.44E-202 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 SUPERFAMILY SSF57783 577 614 2.38E-13 T 12-10-2018 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Gene3D G3DSA:1.10.290.10 251 386 2.0E-169 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Gene3D G3DSA:3.30.65.10 560 619 6.4E-14 T 12-10-2018 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 SMART SM00493 3 103 3.9E-33 T 12-10-2018 IPR006171 TOPRIM domain HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 618 656 8.9E-13 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 659 686 0.025 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 577 614 2.3E-15 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 SMART SM00437 243 511 1.2E-123 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 612 3.5E-262 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 SMART SM00436 104 192 1.1E-53 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Gene3D G3DSA:2.70.20.10 184 458 2.0E-169 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Gene3D G3DSA:1.10.460.10 135 551 2.0E-169 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 280 303 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 Pfam PF01751 Toprim domain 5 113 1.5E-28 T 12-10-2018 IPR006171 TOPRIM domain HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 4.3E-36 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 4.3E-36 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 294 303 4.3E-36 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 371 387 4.3E-36 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_16740 34ec4140ae98267dcf63a58d6bdf513e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 474 488 4.3E-36 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_06625 508336797c31db86934920360dffb2fb 197 Gene3D G3DSA:1.10.10.2520 80 161 1.7E-27 T 12-10-2018 HW35_06625 508336797c31db86934920360dffb2fb 197 Gene3D G3DSA:2.40.10.420 164 197 2.3E-16 T 12-10-2018 HW35_06625 508336797c31db86934920360dffb2fb 197 SUPERFAMILY SSF54106 30 72 1.96E-7 T 12-10-2018 HW35_06625 508336797c31db86934920360dffb2fb 197 Gene3D G3DSA:3.10.350.10 19 79 1.7E-11 T 12-10-2018 IPR036779 LysM domain superfamily HW35_06625 508336797c31db86934920360dffb2fb 197 SMART SM00257 31 72 9.3E-7 T 12-10-2018 IPR018392 LysM domain HW35_06625 508336797c31db86934920360dffb2fb 197 Pfam PF07486 Cell Wall Hydrolase 94 195 2.3E-24 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 HW35_06625 508336797c31db86934920360dffb2fb 197 Pfam PF01476 LysM domain 33 72 2.0E-9 T 12-10-2018 IPR018392 LysM domain HW35_06380 3bad01404a2269dd505eaf84c31607a5 498 Pfam PF00501 AMP-binding enzyme 11 397 2.7E-89 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_06380 3bad01404a2269dd505eaf84c31607a5 498 Gene3D G3DSA:3.40.50.12780 2 394 7.1E-119 T 12-10-2018 HW35_06380 3bad01404a2269dd505eaf84c31607a5 498 Gene3D G3DSA:3.30.300.310 395 495 2.2E-33 T 12-10-2018 HW35_06380 3bad01404a2269dd505eaf84c31607a5 498 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 5 490 46.604 T 12-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 HW35_06380 3bad01404a2269dd505eaf84c31607a5 498 Pfam PF13193 AMP-binding enzyme C-terminal domain 406 481 1.3E-16 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_06380 3bad01404a2269dd505eaf84c31607a5 498 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 30 486 1.6E-144 T 12-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 HW35_06380 3bad01404a2269dd505eaf84c31607a5 498 ProSitePatterns PS00455 Putative AMP-binding domain signature. 154 165 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_06380 3bad01404a2269dd505eaf84c31607a5 498 SUPERFAMILY SSF56801 3 492 6.28E-140 T 12-10-2018 HW35_15250 1e273a24715e6b80167358d7f6a65d97 310 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 219 308 8.3E-36 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HW35_15250 1e273a24715e6b80167358d7f6a65d97 310 SUPERFAMILY SSF53901 3 308 2.4E-75 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_15250 1e273a24715e6b80167358d7f6a65d97 310 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 1.4E-30 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HW35_15250 1e273a24715e6b80167358d7f6a65d97 310 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 308 1.3E-139 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HW35_15250 1e273a24715e6b80167358d7f6a65d97 310 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 308 73.612 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HW35_15250 1e273a24715e6b80167358d7f6a65d97 310 Gene3D G3DSA:3.40.47.10 1 310 5.2E-136 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_02180 40f3e3b3a8323c25583df1a41d7d8437 286 Pfam PF07870 Protein of unknown function (DUF1657) 238 282 2.4E-15 T 12-10-2018 IPR012452 Protein of unknown function DUF1657 HW35_02180 40f3e3b3a8323c25583df1a41d7d8437 286 Gene3D G3DSA:3.30.240.20 170 229 5.6E-14 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily HW35_02180 40f3e3b3a8323c25583df1a41d7d8437 286 Pfam PF04239 Protein of unknown function (DUF421) 89 204 1.3E-32 T 12-10-2018 IPR007353 Protein of unknown function DUF421 HW35_02180 40f3e3b3a8323c25583df1a41d7d8437 286 Gene3D G3DSA:3.30.240.20 81 154 2.1E-25 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 Gene3D G3DSA:3.40.120.10 174 362 5.2E-74 T 12-10-2018 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 Gene3D G3DSA:3.30.310.50 370 448 1.4E-29 T 12-10-2018 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 Gene3D G3DSA:3.40.120.10 3 155 8.2E-58 T 12-10-2018 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 SUPERFAMILY SSF55957 357 446 3.66E-27 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 369 5.1E-37 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 SUPERFAMILY SSF53738 3 180 1.65E-46 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 7.9E-43 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 SUPERFAMILY SSF53738 257 366 1.02E-33 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 SUPERFAMILY SSF53738 158 256 5.89E-27 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 5.2E-17 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 45.651 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 Gene3D G3DSA:3.40.120.10 256 339 5.2E-74 T 12-10-2018 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 6.3E-12 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 6.3E-12 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 6.3E-12 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 5.7E-18 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 442 3.3E-189 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_11085 b0e072ba7682c1d2c5b4d0abcc7d77b2 450 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_08210 1a1f77456d13c6c80c5025ace10358b6 395 SUPERFAMILY SSF53383 7 389 1.2E-125 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_08210 1a1f77456d13c6c80c5025ace10358b6 395 Gene3D G3DSA:3.90.1150.10 28 383 4.3E-136 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_08210 1a1f77456d13c6c80c5025ace10358b6 395 Pfam PF00155 Aminotransferase class I and II 33 383 1.2E-71 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HW35_08210 1a1f77456d13c6c80c5025ace10358b6 395 Gene3D G3DSA:3.40.640.10 64 286 4.3E-136 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_08210 1a1f77456d13c6c80c5025ace10358b6 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 PIRSF PIRSF000804 1 378 1.1E-119 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 SUPERFAMILY SSF55979 1 127 4.91E-25 T 12-10-2018 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 Gene3D G3DSA:3.70.10.10 145 375 6.6E-138 T 12-10-2018 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 SUPERFAMILY SSF55979 254 377 3.81E-32 T 12-10-2018 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 251 1.4E-39 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 SMART SM00480 17 373 4.9E-169 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 SUPERFAMILY SSF55979 132 251 1.26E-29 T 12-10-2018 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 376 4.1E-38 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 377 1.4E-128 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 1.7E-39 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 HW35_09975 3892e8f05f67e0d22d1d22ec6db7aaf6 378 Gene3D G3DSA:3.10.150.10 1 250 6.6E-138 T 12-10-2018 HW35_03900 2bd1f6102c799750033e87762195b592 367 SUPERFAMILY SSF53067 6 176 4.43E-73 T 12-10-2018 HW35_03900 2bd1f6102c799750033e87762195b592 367 PIRSF PIRSF036458 4 359 8.7E-179 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 HW35_03900 2bd1f6102c799750033e87762195b592 367 Pfam PF00871 Acetokinase family 8 343 3.0E-75 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_03900 2bd1f6102c799750033e87762195b592 367 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 8 19 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_03900 2bd1f6102c799750033e87762195b592 367 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 182 199 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_03900 2bd1f6102c799750033e87762195b592 367 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 7 356 1.8E-177 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 HW35_03900 2bd1f6102c799750033e87762195b592 367 Gene3D G3DSA:3.30.420.40 140 335 2.1E-160 T 12-10-2018 HW35_03900 2bd1f6102c799750033e87762195b592 367 Hamap MF_00542 Probable butyrate kinase [buk]. 1 367 173.53 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 HW35_03900 2bd1f6102c799750033e87762195b592 367 PRINTS PR00471 Acetate kinase family signature 182 203 6.8E-17 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_03900 2bd1f6102c799750033e87762195b592 367 PRINTS PR00471 Acetate kinase family signature 8 19 6.8E-17 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_03900 2bd1f6102c799750033e87762195b592 367 PRINTS PR00471 Acetate kinase family signature 300 316 6.8E-17 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_03900 2bd1f6102c799750033e87762195b592 367 PRINTS PR00471 Acetate kinase family signature 277 290 6.8E-17 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_03900 2bd1f6102c799750033e87762195b592 367 SUPERFAMILY SSF53067 120 351 2.41E-57 T 12-10-2018 HW35_03900 2bd1f6102c799750033e87762195b592 367 Gene3D G3DSA:3.30.420.40 7 358 2.1E-160 T 12-10-2018 HW35_08515 c30b7cc8cda1399e7835267aa2d1b09b 45 Pfam PF12841 YvrJ protein family 7 41 2.5E-15 T 12-10-2018 IPR024419 Protein of unknown function YvrJ HW35_02705 776fb5779be7c03a25e4e5bd9338b46b 74 SUPERFAMILY SSF140652 3 70 2.75E-30 T 12-10-2018 IPR036806 YozE SAM-like superfamily HW35_02705 776fb5779be7c03a25e4e5bd9338b46b 74 PIRSF PIRSF037262 1 74 1.5E-34 T 12-10-2018 IPR010673 Protein of unknown function UPF0346 HW35_02705 776fb5779be7c03a25e4e5bd9338b46b 74 Gene3D G3DSA:1.10.150.260 2 71 1.1E-28 T 12-10-2018 IPR036806 YozE SAM-like superfamily HW35_02705 776fb5779be7c03a25e4e5bd9338b46b 74 Pfam PF06855 YozE SAM-like fold 4 69 2.7E-29 T 12-10-2018 IPR023089 YozE SAM-like domain HW35_02705 776fb5779be7c03a25e4e5bd9338b46b 74 Hamap MF_01538 UPF0346 protein . 1 71 25.092 T 12-10-2018 IPR010673 Protein of unknown function UPF0346 HW35_11590 9269b845cf829b8aca8dfd0e342bc53e 385 SUPERFAMILY SSF46785 8 74 2.68E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_11590 9269b845cf829b8aca8dfd0e342bc53e 385 Pfam PF13412 Winged helix-turn-helix DNA-binding 13 56 1.7E-6 T 12-10-2018 HW35_11590 9269b845cf829b8aca8dfd0e342bc53e 385 Gene3D G3DSA:3.30.420.40 81 378 3.7E-91 T 12-10-2018 HW35_11590 9269b845cf829b8aca8dfd0e342bc53e 385 Gene3D G3DSA:1.10.10.10 2 76 5.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_11590 9269b845cf829b8aca8dfd0e342bc53e 385 Gene3D G3DSA:3.30.420.40 205 359 3.7E-91 T 12-10-2018 HW35_11590 9269b845cf829b8aca8dfd0e342bc53e 385 SUPERFAMILY SSF53067 80 379 5.49E-62 T 12-10-2018 HW35_11590 9269b845cf829b8aca8dfd0e342bc53e 385 Pfam PF00480 ROK family 83 375 1.1E-88 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 HW35_11590 9269b845cf829b8aca8dfd0e342bc53e 385 ProSitePatterns PS01125 ROK family signature. 214 241 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 HW35_09430 527197e4113f0cd305adc021056d18f4 77 Gene3D G3DSA:3.10.20.30 1 77 5.1E-24 T 12-10-2018 IPR012675 Beta-grasp domain superfamily HW35_09430 527197e4113f0cd305adc021056d18f4 77 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 77 3.4E-15 T 12-10-2018 IPR010038 MoaD, archaeal-type HW35_09430 527197e4113f0cd305adc021056d18f4 77 Pfam PF02597 ThiS family 4 77 8.8E-20 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 HW35_09430 527197e4113f0cd305adc021056d18f4 77 SUPERFAMILY SSF54285 3 77 3.43E-19 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp HW35_09430 527197e4113f0cd305adc021056d18f4 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 77 4.9E-23 T 12-10-2018 HW35_09645 6cce5cf7823d0ab419756dcf06486e74 478 Gene3D G3DSA:2.40.440.10 352 478 6.1E-37 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like HW35_09645 6cce5cf7823d0ab419756dcf06486e74 478 Pfam PF12229 Putative peptidoglycan binding domain 220 324 1.2E-6 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain HW35_09645 6cce5cf7823d0ab419756dcf06486e74 478 Gene3D G3DSA:1.10.269.20 217 334 9.8E-16 T 12-10-2018 IPR038054 L,D-transpeptidase central domain-like superfamily HW35_09645 6cce5cf7823d0ab419756dcf06486e74 478 SUPERFAMILY SSF141523 350 478 1.44E-29 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like HW35_09645 6cce5cf7823d0ab419756dcf06486e74 478 SUPERFAMILY SSF143985 217 335 2.48E-27 T 12-10-2018 IPR038054 L,D-transpeptidase central domain-like superfamily HW35_09645 6cce5cf7823d0ab419756dcf06486e74 478 Pfam PF03734 L,D-transpeptidase catalytic domain 353 477 2.1E-14 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 HW35_16600 875a3c00c268f2e48f6850d0002d6d07 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 5.3E-23 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16600 875a3c00c268f2e48f6850d0002d6d07 62 Gene3D G3DSA:2.30.170.40 19 62 2.7E-18 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16600 875a3c00c268f2e48f6850d0002d6d07 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.911 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16600 875a3c00c268f2e48f6850d0002d6d07 62 Pfam PF00830 Ribosomal L28 family 3 58 8.5E-21 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16600 875a3c00c268f2e48f6850d0002d6d07 62 SUPERFAMILY SSF143800 1 61 3.34E-23 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_17435 9e95cc8edbac966ed4adf16594d0da05 382 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 21 377 51.374 T 12-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 HW35_17435 9e95cc8edbac966ed4adf16594d0da05 382 Gene3D G3DSA:3.40.50.620 165 375 3.1E-99 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_17435 9e95cc8edbac966ed4adf16594d0da05 382 Gene3D G3DSA:3.10.400.10 21 158 2.8E-47 T 12-10-2018 HW35_17435 9e95cc8edbac966ed4adf16594d0da05 382 Pfam PF14306 PUA-like domain 6 155 3.1E-48 T 12-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HW35_17435 9e95cc8edbac966ed4adf16594d0da05 382 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 6 372 4.9E-139 T 12-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HW35_17435 9e95cc8edbac966ed4adf16594d0da05 382 SUPERFAMILY SSF52374 162 373 1.41E-87 T 12-10-2018 HW35_17435 9e95cc8edbac966ed4adf16594d0da05 382 Pfam PF01747 ATP-sulfurylase 163 373 2.4E-97 T 12-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HW35_17435 9e95cc8edbac966ed4adf16594d0da05 382 SUPERFAMILY SSF88697 5 158 9.94E-48 T 12-10-2018 IPR015947 PUA-like superfamily HW35_09295 474c340d0fcb2d97f622a290497ed511 463 SUPERFAMILY SSF56024 272 444 4.04E-39 T 12-10-2018 HW35_09295 474c340d0fcb2d97f622a290497ed511 463 Gene3D G3DSA:3.30.870.10 43 229 2.6E-40 T 12-10-2018 HW35_09295 474c340d0fcb2d97f622a290497ed511 463 SUPERFAMILY SSF56024 32 215 1.98E-41 T 12-10-2018 HW35_09295 474c340d0fcb2d97f622a290497ed511 463 Gene3D G3DSA:3.30.870.10 267 460 7.7E-31 T 12-10-2018 HW35_09295 474c340d0fcb2d97f622a290497ed511 463 PIRSF PIRSF000850 20 123 1.1 T 12-10-2018 HW35_09295 474c340d0fcb2d97f622a290497ed511 463 PIRSF PIRSF000850 360 441 0.1 T 12-10-2018 HW35_09295 474c340d0fcb2d97f622a290497ed511 463 PIRSF PIRSF000850 291 375 0.0024 T 12-10-2018 HW35_09295 474c340d0fcb2d97f622a290497ed511 463 Pfam PF13091 PLD-like domain 304 430 1.5E-27 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 HW35_09295 474c340d0fcb2d97f622a290497ed511 463 Pfam PF13091 PLD-like domain 60 197 2.2E-13 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 HW35_09295 474c340d0fcb2d97f622a290497ed511 463 SMART SM00155 141 168 0.001 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 HW35_09295 474c340d0fcb2d97f622a290497ed511 463 SMART SM00155 376 403 2.8E-6 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 Gene3D G3DSA:3.50.50.60 152 274 1.8E-125 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 282 2.3E-77 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 2.3E-77 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 411 426 2.3E-77 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 2.3E-77 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 2.3E-77 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 2.3E-77 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 346 367 2.3E-77 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 2.3E-77 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 433 453 2.3E-77 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 SUPERFAMILY SSF55424 346 469 2.75E-41 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 5.0E-43 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 5.0E-43 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 5.0E-43 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 283 5.0E-43 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 5.0E-43 T 12-10-2018 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 SUPERFAMILY SSF51905 7 341 1.83E-66 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 PIRSF PIRSF000350 3 460 4.3E-99 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 350 458 5.4E-38 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 Gene3D G3DSA:3.50.50.60 13 336 1.8E-125 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 331 1.0E-73 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 469 1.4E-176 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 HW35_15945 6f3aa46dce33910eb9d62e31fda556c4 471 Gene3D G3DSA:3.30.390.30 349 469 3.4E-44 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 HW35_08465 9b882546b744bdbe9f35ddc06786c2c4 430 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 13 429 9.2E-164 T 12-10-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 HW35_08465 9b882546b744bdbe9f35ddc06786c2c4 430 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 68 419 9.1E-96 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 HW35_08465 9b882546b744bdbe9f35ddc06786c2c4 430 SUPERFAMILY SSF54909 63 423 6.26E-94 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel HW35_08465 9b882546b744bdbe9f35ddc06786c2c4 430 Pfam PF04261 Dyp-type peroxidase family 68 419 3.5E-107 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 HW35_16920 f54d721958751c179f77d392fe3db2af 783 Gene3D G3DSA:1.10.10.10 716 779 3.1E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_16920 f54d721958751c179f77d392fe3db2af 783 Gene3D G3DSA:3.40.50.300 418 703 9.3E-111 T 12-10-2018 HW35_16920 f54d721958751c179f77d392fe3db2af 783 Pfam PF01580 FtsK/SpoIIIE family 421 617 4.7E-64 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HW35_16920 f54d721958751c179f77d392fe3db2af 783 Gene3D G3DSA:3.30.980.40 313 416 5.5E-38 T 12-10-2018 HW35_16920 f54d721958751c179f77d392fe3db2af 783 SUPERFAMILY SSF46785 713 778 5.58E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_16920 f54d721958751c179f77d392fe3db2af 783 SMART SM00382 456 638 4.9E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_16920 f54d721958751c179f77d392fe3db2af 783 SMART SM00843 712 777 6.4E-41 T 12-10-2018 IPR018541 FtsK gamma domain HW35_16920 f54d721958751c179f77d392fe3db2af 783 Pfam PF09397 Ftsk gamma domain 715 774 3.7E-30 T 12-10-2018 IPR018541 FtsK gamma domain HW35_16920 f54d721958751c179f77d392fe3db2af 783 SUPERFAMILY SSF52540 394 689 1.95E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 Pfam PF04539 Sigma-70 region 3 115 181 5.6E-13 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 SUPERFAMILY SSF88659 109 184 6.1E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 SUPERFAMILY SSF88659 171 250 2.62E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 SUPERFAMILY SSF88946 7 105 5.1E-34 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 Pfam PF04545 Sigma-70, region 4 199 247 2.3E-15 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 30 250 1.9E-87 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 Gene3D G3DSA:1.10.601.10 4 104 2.5E-27 T 12-10-2018 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 Pfam PF04542 Sigma-70 region 2 38 104 1.2E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 PRINTS PR00046 Major sigma-70 factor signature 235 246 2.0E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 PRINTS PR00046 Major sigma-70 factor signature 85 93 2.0E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 PRINTS PR00046 Major sigma-70 factor signature 220 235 2.0E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 PRINTS PR00046 Major sigma-70 factor signature 61 74 2.0E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 PRINTS PR00046 Major sigma-70 factor signature 203 215 2.0E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 249 3.5E-36 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 22 250 3.3E-115 T 12-10-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 220 246 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 Gene3D G3DSA:1.10.10.10 186 251 4.6E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 61 74 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 PIRSF PIRSF000770 8 252 2.1E-37 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_03670 18e06cf7227cb4b26eeb7f36f71eb512 252 Gene3D G3DSA:1.10.10.10 105 160 1.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_05585 871d46246d813ecf370bec2fea3315b5 309 Pfam PF07319 Primosomal protein DnaI N-terminus 1 98 1.3E-31 T 12-10-2018 IPR009928 Primosomal DnaI, N-terminal HW35_05585 871d46246d813ecf370bec2fea3315b5 309 Pfam PF01695 IstB-like ATP binding protein 130 268 7.3E-11 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HW35_05585 871d46246d813ecf370bec2fea3315b5 309 SUPERFAMILY SSF52540 128 273 5.07E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05585 871d46246d813ecf370bec2fea3315b5 309 SMART SM00382 159 306 0.0092 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_05585 871d46246d813ecf370bec2fea3315b5 309 Gene3D G3DSA:3.40.50.300 108 301 6.1E-53 T 12-10-2018 HW35_02945 53c187087cb11bf88a1cd434d218a6f8 141 SUPERFAMILY SSF47979 63 131 5.1E-20 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 HW35_02945 53c187087cb11bf88a1cd434d218a6f8 141 SMART SM00529 24 123 1.7E-42 T 12-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 HW35_02945 53c187087cb11bf88a1cd434d218a6f8 141 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 59 2.0E-25 T 12-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 HW35_02945 53c187087cb11bf88a1cd434d218a6f8 141 Gene3D G3DSA:1.10.10.10 2 73 1.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_02945 53c187087cb11bf88a1cd434d218a6f8 141 Gene3D G3DSA:1.10.60.10 74 141 2.1E-30 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 HW35_02945 53c187087cb11bf88a1cd434d218a6f8 141 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 44.025 T 12-10-2018 IPR022897 HTH-type transcription regulator MntR HW35_02945 53c187087cb11bf88a1cd434d218a6f8 141 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 125 1.4E-19 T 12-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 HW35_02945 53c187087cb11bf88a1cd434d218a6f8 141 SUPERFAMILY SSF46785 3 61 3.57E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_04815 e87a2abc5e0a3127cfcb8e395f424dcb 380 PIRSF PIRSF005572 1 380 4.5E-123 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 HW35_04815 e87a2abc5e0a3127cfcb8e395f424dcb 380 Gene3D G3DSA:3.40.640.10 61 235 2.3E-141 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_04815 e87a2abc5e0a3127cfcb8e395f424dcb 380 Pfam PF00266 Aminotransferase class-V 4 364 8.4E-79 T 12-10-2018 IPR000192 Aminotransferase class V domain HW35_04815 e87a2abc5e0a3127cfcb8e395f424dcb 380 Gene3D G3DSA:3.90.1150.10 4 369 2.3E-141 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_04815 e87a2abc5e0a3127cfcb8e395f424dcb 380 SUPERFAMILY SSF53383 3 375 1.1E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_04815 e87a2abc5e0a3127cfcb8e395f424dcb 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site HW35_04815 e87a2abc5e0a3127cfcb8e395f424dcb 380 Gene3D G3DSA:1.10.260.50 15 278 2.3E-141 T 12-10-2018 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 Gene3D G3DSA:1.10.340.30 22 133 7.2E-83 T 12-10-2018 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 SUPERFAMILY SSF48150 3 211 4.71E-74 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 38 170 3.1E-24 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 TIGRFAM TIGR01083 nth: endonuclease III 6 196 1.3E-87 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 SMART SM00478 39 187 6.9E-70 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 Hamap MF_00942 Endonuclease III [nth]. 1 211 39.302 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 Gene3D G3DSA:1.10.1670.10 16 205 7.2E-83 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 5.8E-4 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 SMART SM00525 188 208 9.8E-4 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 PIRSF PIRSF001435 3 214 2.5E-59 T 12-10-2018 HW35_03175 369ee4828da70665e8d20e1c6a7dcbdf 221 Pfam PF00633 Helix-hairpin-helix motif 100 128 2.8E-11 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 HW35_04490 c273389b89b4613e1eeb4c67bed1fb11 320 SUPERFAMILY SSF52540 112 292 1.14E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04490 c273389b89b4613e1eeb4c67bed1fb11 320 Pfam PF02562 PhoH-like protein 113 316 5.8E-97 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 HW35_04490 c273389b89b4613e1eeb4c67bed1fb11 320 Gene3D G3DSA:3.40.50.300 109 316 2.9E-76 T 12-10-2018 HW35_06375 640cff0a42854e00117400c48f38eaf8 368 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 7 125 3.6E-16 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain HW35_06375 640cff0a42854e00117400c48f38eaf8 368 SMART SM00922 142 234 4.5E-21 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal HW35_06375 640cff0a42854e00117400c48f38eaf8 368 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 100 125 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 HW35_06375 640cff0a42854e00117400c48f38eaf8 368 SUPERFAMILY SSF54826 1 126 1.11E-33 T 12-10-2018 HW35_06375 640cff0a42854e00117400c48f38eaf8 368 Gene3D G3DSA:3.20.20.120 118 346 1.3E-129 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily HW35_06375 640cff0a42854e00117400c48f38eaf8 368 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 332 2.4E-118 T 12-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 HW35_06375 640cff0a42854e00117400c48f38eaf8 368 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 43.959 T 12-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 HW35_06375 640cff0a42854e00117400c48f38eaf8 368 Gene3D G3DSA:3.30.390.10 10 357 1.3E-129 T 12-10-2018 IPR029017 Enolase-like, N-terminal HW35_06375 640cff0a42854e00117400c48f38eaf8 368 Pfam PF13378 Enolase C-terminal domain-like 146 354 2.1E-40 T 12-10-2018 IPR029065 Enolase C-terminal domain-like HW35_06375 640cff0a42854e00117400c48f38eaf8 368 SUPERFAMILY SSF51604 114 362 2.23E-65 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 SMART SM00387 392 498 1.4E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 SUPERFAMILY SSF47384 275 347 3.73E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 495 1.7E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 SUPERFAMILY SSF55874 351 496 9.17E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 495 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 457 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 476 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 443 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 Pfam PF02743 Cache domain 40 202 2.5E-13 T 12-10-2018 IPR033479 Double Cache domain 1 HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 Pfam PF00512 His Kinase A (phospho-acceptor) domain 287 348 3.5E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 Gene3D G3DSA:1.10.287.130 288 347 1.3E-16 T 12-10-2018 HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 Gene3D G3DSA:3.30.565.10 351 500 8.0E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 Gene3D G3DSA:3.30.450.20 74 173 5.9E-48 T 12-10-2018 HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 Gene3D G3DSA:3.30.450.20 45 226 5.9E-48 T 12-10-2018 HW35_15750 5ed627e4634c9f1a9c515d63329caa50 500 SMART SM00388 285 350 3.2E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_13385 d49c99f67c5b8acfd8f9367279130e87 404 Pfam PF07690 Major Facilitator Superfamily 14 269 7.9E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_13385 d49c99f67c5b8acfd8f9367279130e87 404 Gene3D G3DSA:1.20.1250.20 217 403 4.8E-25 T 12-10-2018 HW35_13385 d49c99f67c5b8acfd8f9367279130e87 404 SUPERFAMILY SSF103473 6 398 1.44E-69 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_13385 d49c99f67c5b8acfd8f9367279130e87 404 PRINTS PR01035 Tetracycline resistance protein signature 82 106 5.3E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_13385 d49c99f67c5b8acfd8f9367279130e87 404 PRINTS PR01035 Tetracycline resistance protein signature 51 70 5.3E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_13385 d49c99f67c5b8acfd8f9367279130e87 404 PRINTS PR01035 Tetracycline resistance protein signature 343 366 5.3E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_13385 d49c99f67c5b8acfd8f9367279130e87 404 PRINTS PR01035 Tetracycline resistance protein signature 139 161 5.3E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_13385 d49c99f67c5b8acfd8f9367279130e87 404 Gene3D G3DSA:1.20.1250.20 7 193 2.6E-36 T 12-10-2018 HW35_03300 125ce54d5ba521f77bf20688fa5c8e2f 186 Gene3D G3DSA:4.10.810.10 124 184 2.3E-19 T 12-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 HW35_03300 125ce54d5ba521f77bf20688fa5c8e2f 186 Gene3D G3DSA:1.20.1440.290 1 123 1.8E-56 T 12-10-2018 IPR038091 UPF0302, N-terminal domain superfamily HW35_03300 125ce54d5ba521f77bf20688fa5c8e2f 186 PIRSF PIRSF007165 1 183 8.2E-81 T 12-10-2018 IPR011188 Uncharacterised protein family UPF0302 HW35_03300 125ce54d5ba521f77bf20688fa5c8e2f 186 Pfam PF08858 IDEAL domain 140 175 1.7E-10 T 12-10-2018 IPR014957 IDEAL domain HW35_03300 125ce54d5ba521f77bf20688fa5c8e2f 186 SMART SM00914 139 175 1.2E-8 T 12-10-2018 IPR014957 IDEAL domain HW35_03300 125ce54d5ba521f77bf20688fa5c8e2f 186 Hamap MF_00760 UPF0302 protein . 2 178 32.437 T 12-10-2018 IPR011188 Uncharacterised protein family UPF0302 HW35_03300 125ce54d5ba521f77bf20688fa5c8e2f 186 Pfam PF08864 UPF0302 domain 9 113 4.8E-48 T 12-10-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal HW35_14200 30cc6a29eadf6a045d7f8d60bf603382 453 Pfam PF05598 Transposase domain (DUF772) 53 128 2.7E-23 T 12-10-2018 IPR008490 Transposase InsH, N-terminal HW35_14200 30cc6a29eadf6a045d7f8d60bf603382 453 Pfam PF13751 Transposase DDE domain 324 442 1.6E-27 T 12-10-2018 IPR025668 Transposase DDE domain HW35_08580 30cc6a29eadf6a045d7f8d60bf603382 453 Pfam PF05598 Transposase domain (DUF772) 53 128 2.7E-23 T 12-10-2018 IPR008490 Transposase InsH, N-terminal HW35_08580 30cc6a29eadf6a045d7f8d60bf603382 453 Pfam PF13751 Transposase DDE domain 324 442 1.6E-27 T 12-10-2018 IPR025668 Transposase DDE domain HW35_10030 30cc6a29eadf6a045d7f8d60bf603382 453 Pfam PF05598 Transposase domain (DUF772) 53 128 2.7E-23 T 12-10-2018 IPR008490 Transposase InsH, N-terminal HW35_10030 30cc6a29eadf6a045d7f8d60bf603382 453 Pfam PF13751 Transposase DDE domain 324 442 1.6E-27 T 12-10-2018 IPR025668 Transposase DDE domain HW35_02350 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_02350 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_02350 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_02350 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_06025 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_06025 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_06025 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_06025 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_02420 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_02420 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_02420 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_02420 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_05200 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_05200 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_05200 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_05200 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_00625 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_00625 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_00625 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_00625 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_14035 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_14035 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_14035 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_14035 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_14575 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_14575 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_14575 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_14575 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_12860 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_12860 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_12860 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_12860 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_05385 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_05385 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_05385 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_05385 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_15850 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_15850 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_15850 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_15850 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_00325 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_00325 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_00325 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_00325 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_17465 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_17465 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_17465 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_17465 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_11440 d2f049423d0dcbb4bd18023176791205 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_11440 d2f049423d0dcbb4bd18023176791205 277 Gene3D G3DSA:3.30.420.10 109 267 5.8E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_11440 d2f049423d0dcbb4bd18023176791205 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_11440 d2f049423d0dcbb4bd18023176791205 277 Pfam PF13276 HTH-like domain 35 87 1.6E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_11710 905f297df71e498255d705384d0817c1 741 SUPERFAMILY SSF56042 572 738 6.13E-39 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HW35_11710 905f297df71e498255d705384d0817c1 741 PIRSF PIRSF001587 8 740 0.0 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HW35_11710 905f297df71e498255d705384d0817c1 741 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 736 0.0 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HW35_11710 905f297df71e498255d705384d0817c1 741 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 741 334.801 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HW35_11710 905f297df71e498255d705384d0817c1 741 SUPERFAMILY SSF55326 404 570 8.5E-60 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HW35_11710 905f297df71e498255d705384d0817c1 741 SUPERFAMILY SSF56042 205 430 3.44E-59 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HW35_11710 905f297df71e498255d705384d0817c1 741 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 360 1.3E-35 T 12-10-2018 IPR010918 PurM-like, C-terminal domain HW35_11710 905f297df71e498255d705384d0817c1 741 Pfam PF02769 AIR synthase related protein, C-terminal domain 576 710 2.7E-14 T 12-10-2018 IPR010918 PurM-like, C-terminal domain HW35_11710 905f297df71e498255d705384d0817c1 741 Gene3D G3DSA:3.90.650.10 569 739 3.9E-43 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HW35_11710 905f297df71e498255d705384d0817c1 741 Pfam PF00586 AIR synthase related protein, N-terminal domain 91 194 7.8E-25 T 12-10-2018 IPR016188 PurM-like, N-terminal domain HW35_11710 905f297df71e498255d705384d0817c1 741 Pfam PF00586 AIR synthase related protein, N-terminal domain 457 562 7.6E-26 T 12-10-2018 IPR016188 PurM-like, N-terminal domain HW35_11710 905f297df71e498255d705384d0817c1 741 Gene3D G3DSA:3.30.1330.10 392 564 1.5E-63 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HW35_11710 905f297df71e498255d705384d0817c1 741 Gene3D G3DSA:3.90.650.10 34 362 4.3E-137 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HW35_11710 905f297df71e498255d705384d0817c1 741 Gene3D G3DSA:3.30.1330.10 49 198 4.3E-137 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HW35_11710 905f297df71e498255d705384d0817c1 741 SUPERFAMILY SSF55326 18 201 1.47E-52 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HW35_12255 25c4b2c4b860ff39670b682b99298fea 420 SUPERFAMILY SSF56672 22 346 3.43E-58 T 12-10-2018 HW35_12255 25c4b2c4b860ff39670b682b99298fea 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_12255 25c4b2c4b860ff39670b682b99298fea 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_12255 25c4b2c4b860ff39670b682b99298fea 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_12255 25c4b2c4b860ff39670b682b99298fea 420 Pfam PF08388 Group II intron, maturase-specific domain 288 360 4.0E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_12255 25c4b2c4b860ff39670b682b99298fea 420 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 3.4E-49 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_12255 25c4b2c4b860ff39670b682b99298fea 420 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 6.3E-131 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_10050 0b33e39c2227648e546dbf02ccaf03fb 293 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 3 293 54.294 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HW35_10050 0b33e39c2227648e546dbf02ccaf03fb 293 Gene3D G3DSA:3.20.20.70 1 293 5.1E-148 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_10050 0b33e39c2227648e546dbf02ccaf03fb 293 SUPERFAMILY SSF51366 17 267 1.13E-70 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HW35_10050 0b33e39c2227648e546dbf02ccaf03fb 293 ProSitePatterns PS01235 PdxS/SNZ family signature. 204 222 - T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HW35_10050 0b33e39c2227648e546dbf02ccaf03fb 293 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 8 293 7.8E-157 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HW35_10050 0b33e39c2227648e546dbf02ccaf03fb 293 Pfam PF01680 SOR/SNZ family 7 211 4.6E-106 T 12-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HW35_10050 0b33e39c2227648e546dbf02ccaf03fb 293 PIRSF PIRSF029271 1 293 1.8E-153 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HW35_04190 72de1eab91544fb6bedff84dc0cc4771 146 SUPERFAMILY SSF54523 8 83 7.46E-6 T 12-10-2018 HW35_04190 72de1eab91544fb6bedff84dc0cc4771 146 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_04190 72de1eab91544fb6bedff84dc0cc4771 146 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 20 2.4E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_04190 72de1eab91544fb6bedff84dc0cc4771 146 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 26 2.0E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_04190 72de1eab91544fb6bedff84dc0cc4771 146 PIRSF PIRSF021292 1 146 1.2E-39 T 12-10-2018 IPR016785 ComG operon protein 4 GO:0030420 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Pfam PF01584 CheW-like domain 542 670 2.9E-26 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Gene3D G3DSA:3.30.70.1110 164 248 1.7E-25 T 12-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 SUPERFAMILY SSF55052 164 247 5.75E-22 T 12-10-2018 IPR035891 CheY-binding domain of CheA HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 SUPERFAMILY SSF47384 289 349 1.1E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 SMART SM00260 528 669 6.2E-36 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 396 535 3.4E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 289 347 5.4E-13 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 SUPERFAMILY SSF50341 535 668 4.71E-31 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 SMART SM01231 288 348 9.1E-19 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Pfam PF01627 Hpt domain 6 105 4.2E-20 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 SUPERFAMILY SSF47226 4 125 1.57E-32 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 533 3.3E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 452 3.3E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 514 3.3E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 SMART SM00387 393 536 1.6E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Gene3D G3DSA:3.30.565.10 349 535 4.3E-61 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Pfam PF07194 P2 response regulator binding domain 167 247 1.2E-26 T 12-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 SUPERFAMILY SSF55874 350 534 4.58E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Gene3D G3DSA:1.20.120.160 3 139 5.4E-39 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Gene3D G3DSA:2.40.50.180 559 624 6.5E-39 T 12-10-2018 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Gene3D G3DSA:1.10.287.560 288 348 3.4E-20 T 12-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 Gene3D G3DSA:2.30.30.40 536 664 6.5E-39 T 12-10-2018 HW35_00245 b22f17336d8b3e4fef7ad16f252cee22 673 SMART SM00073 3 100 9.2E-33 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 HW35_00275 4afae96afb6f06c8182a955d0821a7bf 280 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 197 278 9.7E-20 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HW35_00275 4afae96afb6f06c8182a955d0821a7bf 280 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site HW35_00275 4afae96afb6f06c8182a955d0821a7bf 280 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 125 6.3E-32 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G HW35_00275 4afae96afb6f06c8182a955d0821a7bf 280 SUPERFAMILY SSF117143 93 210 9.15E-16 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like HW35_00275 4afae96afb6f06c8182a955d0821a7bf 280 Pfam PF00460 Flagella basal body rod protein 8 35 5.9E-10 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HW35_01740 f56efd80dc6e989940ca95f486632c08 383 SUPERFAMILY SSF55874 215 379 1.7E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_01740 f56efd80dc6e989940ca95f486632c08 383 Pfam PF00512 His Kinase A (phospho-acceptor) domain 159 221 2.7E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_01740 f56efd80dc6e989940ca95f486632c08 383 Gene3D G3DSA:1.10.287.130 122 223 4.7E-15 T 12-10-2018 HW35_01740 f56efd80dc6e989940ca95f486632c08 383 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 270 377 6.6E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_01740 f56efd80dc6e989940ca95f486632c08 383 SMART SM00387 270 380 2.0E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_01740 f56efd80dc6e989940ca95f486632c08 383 SUPERFAMILY SSF47384 142 223 1.45E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_01740 f56efd80dc6e989940ca95f486632c08 383 SMART SM00388 158 225 4.9E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_01740 f56efd80dc6e989940ca95f486632c08 383 Gene3D G3DSA:3.30.565.10 229 381 2.0E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_01740 f56efd80dc6e989940ca95f486632c08 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 359 3.2E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_01740 f56efd80dc6e989940ca95f486632c08 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 377 3.2E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_01740 f56efd80dc6e989940ca95f486632c08 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 334 3.2E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_16710 b1b285b4beec0661a3d86e7376fca57b 185 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 176 5.0E-58 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HW35_16710 b1b285b4beec0661a3d86e7376fca57b 185 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 HW35_16710 b1b285b4beec0661a3d86e7376fca57b 185 Pfam PF00717 Peptidase S24-like 35 102 5.7E-22 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HW35_16710 b1b285b4beec0661a3d86e7376fca57b 185 ProSitePatterns PS00760 Signal peptidases I lysine active site. 80 92 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 HW35_16710 b1b285b4beec0661a3d86e7376fca57b 185 Gene3D G3DSA:2.10.109.10 58 184 6.3E-47 T 12-10-2018 HW35_16710 b1b285b4beec0661a3d86e7376fca57b 185 SUPERFAMILY SSF51306 26 182 7.85E-55 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily HW35_16710 b1b285b4beec0661a3d86e7376fca57b 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 5.0E-22 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HW35_16710 b1b285b4beec0661a3d86e7376fca57b 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 78 90 5.0E-22 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HW35_16710 b1b285b4beec0661a3d86e7376fca57b 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 5.0E-22 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HW35_16710 b1b285b4beec0661a3d86e7376fca57b 185 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 HW35_06270 b64c791f4fdcbffdd86d3ebb7248bec1 209 Pfam PF00005 ABC transporter 17 157 2.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_06270 b64c791f4fdcbffdd86d3ebb7248bec1 209 Gene3D G3DSA:3.40.50.300 1 209 1.1E-47 T 12-10-2018 HW35_06270 b64c791f4fdcbffdd86d3ebb7248bec1 209 SUPERFAMILY SSF52540 2 208 2.42E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_06270 b64c791f4fdcbffdd86d3ebb7248bec1 209 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_06270 b64c791f4fdcbffdd86d3ebb7248bec1 209 SMART SM00382 26 206 1.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_10785 6ab3c13a1ce40cfbcc6ad24ed5b332a9 132 Pfam PF00410 Ribosomal protein S8 5 132 4.6E-55 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10785 6ab3c13a1ce40cfbcc6ad24ed5b332a9 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.195 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10785 6ab3c13a1ce40cfbcc6ad24ed5b332a9 132 Gene3D G3DSA:3.30.1370.30 4 74 2.0E-34 T 12-10-2018 HW35_10785 6ab3c13a1ce40cfbcc6ad24ed5b332a9 132 Gene3D G3DSA:3.30.1490.10 75 132 1.3E-26 T 12-10-2018 HW35_10785 6ab3c13a1ce40cfbcc6ad24ed5b332a9 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10785 6ab3c13a1ce40cfbcc6ad24ed5b332a9 132 SUPERFAMILY SSF56047 2 132 5.63E-50 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_06660 ddf4e109a9dbdd777c4dd5be855366a8 395 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 192 206 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_06660 ddf4e109a9dbdd777c4dd5be855366a8 395 SUPERFAMILY SSF53383 19 384 5.5E-114 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_06660 ddf4e109a9dbdd777c4dd5be855366a8 395 Gene3D G3DSA:3.40.640.10 7 250 1.5E-88 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_06660 ddf4e109a9dbdd777c4dd5be855366a8 395 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 382 1.2E-146 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_06660 ddf4e109a9dbdd777c4dd5be855366a8 395 PIRSF PIRSF001434 1 385 8.9E-144 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_06660 ddf4e109a9dbdd777c4dd5be855366a8 395 Gene3D G3DSA:3.90.1150.10 251 391 1.1E-48 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_10745 c6575d9b8fd9c1b688087bfb12611d8f 218 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.384 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 HW35_10745 c6575d9b8fd9c1b688087bfb12611d8f 218 Pfam PF07650 KH domain 37 108 1.2E-20 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10745 c6575d9b8fd9c1b688087bfb12611d8f 218 SUPERFAMILY SSF54821 107 205 1.31E-38 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10745 c6575d9b8fd9c1b688087bfb12611d8f 218 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 7.3E-96 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 HW35_10745 c6575d9b8fd9c1b688087bfb12611d8f 218 SUPERFAMILY SSF54814 2 105 5.76E-39 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 HW35_10745 c6575d9b8fd9c1b688087bfb12611d8f 218 Gene3D G3DSA:3.30.300.20 17 106 3.6E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta HW35_10745 c6575d9b8fd9c1b688087bfb12611d8f 218 Gene3D G3DSA:3.30.1140.32 107 207 5.0E-41 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10745 c6575d9b8fd9c1b688087bfb12611d8f 218 SMART SM00322 59 124 6.0E-7 T 12-10-2018 IPR004087 K Homology domain GO:0003676 HW35_10745 c6575d9b8fd9c1b688087bfb12611d8f 218 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10745 c6575d9b8fd9c1b688087bfb12611d8f 218 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 9.5E-41 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_08370 4641858ace2e0e2d081dff6646b92001 212 SUPERFAMILY SSF51366 2 208 3.93E-31 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HW35_08370 4641858ace2e0e2d081dff6646b92001 212 SMART SM00934 2 202 7.9E-35 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_08370 4641858ace2e0e2d081dff6646b92001 212 Gene3D G3DSA:3.20.20.70 1 210 7.5E-66 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_08370 4641858ace2e0e2d081dff6646b92001 212 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 202 3.7E-23 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_03075 e11a58a980811aa3643f5a4f55b98aee 378 SUPERFAMILY SSF53335 143 360 1.59E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_03075 e11a58a980811aa3643f5a4f55b98aee 378 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 12-10-2018 IPR000241 Putative RNA methylase domain HW35_03075 e11a58a980811aa3643f5a4f55b98aee 378 Gene3D G3DSA:3.40.50.150 160 365 1.0E-125 T 12-10-2018 HW35_03075 e11a58a980811aa3643f5a4f55b98aee 378 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 299 305 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HW35_03075 e11a58a980811aa3643f5a4f55b98aee 378 Pfam PF01170 Putative RNA methylase family UPF0020 162 366 1.3E-67 T 12-10-2018 IPR000241 Putative RNA methylase domain HW35_03075 e11a58a980811aa3643f5a4f55b98aee 378 Gene3D G3DSA:3.30.2130.30 8 245 1.0E-125 T 12-10-2018 HW35_03075 e11a58a980811aa3643f5a4f55b98aee 378 SMART SM00981 57 154 7.0E-7 T 12-10-2018 IPR004114 THUMP domain GO:0003723 HW35_03075 e11a58a980811aa3643f5a4f55b98aee 378 Pfam PF02926 THUMP domain 19 153 1.4E-14 T 12-10-2018 IPR004114 THUMP domain GO:0003723 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 SUPERFAMILY SSF53850 2 217 1.09E-83 T 12-10-2018 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 12-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 295 4.8E-114 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 PIRSF PIRSF001438 1 309 7.5E-124 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 1.3E-81 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 Gene3D G3DSA:3.30.160.40 220 304 2.3E-27 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 Gene3D G3DSA:3.40.190.10 4 209 2.8E-86 T 12-10-2018 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 SUPERFAMILY SSF54782 220 307 6.41E-22 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 293 4.9E-18 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 39.079 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 Gene3D G3DSA:3.40.190.10 101 201 2.8E-86 T 12-10-2018 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 1.8E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 1.8E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 1.8E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 1.8E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05230 a2b619f82609ab10b3ea9db1e4791341 311 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 1.8E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_10275 47de46fb51688a4c6fb9feb4c160615c 205 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 20 205 2.9E-70 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HW35_10275 47de46fb51688a4c6fb9feb4c160615c 205 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 33 46 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 HW35_10275 47de46fb51688a4c6fb9feb4c160615c 205 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 126 136 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 HW35_10275 47de46fb51688a4c6fb9feb4c160615c 205 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 20 197 37.286 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HW35_10275 47de46fb51688a4c6fb9feb4c160615c 205 Pfam PF01195 Peptidyl-tRNA hydrolase 22 204 3.5E-59 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HW35_10275 47de46fb51688a4c6fb9feb4c160615c 205 SUPERFAMILY SSF53178 19 204 1.96E-70 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 HW35_10275 47de46fb51688a4c6fb9feb4c160615c 205 Gene3D G3DSA:3.40.50.1470 20 205 1.5E-72 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 HW35_13245 dd79623ef61a6a4380bdb2d5be6a91f2 348 SUPERFAMILY SSF51735 132 310 4.54E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_13245 dd79623ef61a6a4380bdb2d5be6a91f2 348 Gene3D G3DSA:3.90.180.10 23 327 1.9E-100 T 12-10-2018 HW35_13245 dd79623ef61a6a4380bdb2d5be6a91f2 348 Gene3D G3DSA:3.40.50.720 147 284 1.9E-100 T 12-10-2018 HW35_13245 dd79623ef61a6a4380bdb2d5be6a91f2 348 Pfam PF00107 Zinc-binding dehydrogenase 170 294 2.0E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 HW35_13245 dd79623ef61a6a4380bdb2d5be6a91f2 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 HW35_13245 dd79623ef61a6a4380bdb2d5be6a91f2 348 SUPERFAMILY SSF50129 2 168 8.22E-48 T 12-10-2018 IPR011032 GroES-like superfamily HW35_13245 dd79623ef61a6a4380bdb2d5be6a91f2 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 1.3E-31 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HW35_13245 dd79623ef61a6a4380bdb2d5be6a91f2 348 SMART SM00829 7 343 8.1E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HW35_14270 71bf888649f7a3c9a0380700e2fd2869 589 SMART SM00382 368 556 3.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_14270 71bf888649f7a3c9a0380700e2fd2869 589 Gene3D G3DSA:1.20.1560.10 4 325 3.7E-110 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_14270 71bf888649f7a3c9a0380700e2fd2869 589 Gene3D G3DSA:3.40.50.300 332 588 2.1E-96 T 12-10-2018 HW35_14270 71bf888649f7a3c9a0380700e2fd2869 589 Pfam PF00664 ABC transporter transmembrane region 19 293 4.5E-43 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 HW35_14270 71bf888649f7a3c9a0380700e2fd2869 589 SUPERFAMILY SSF52540 331 579 8.38E-98 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14270 71bf888649f7a3c9a0380700e2fd2869 589 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_14270 71bf888649f7a3c9a0380700e2fd2869 589 SUPERFAMILY SSF90123 6 325 2.88E-78 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_14270 71bf888649f7a3c9a0380700e2fd2869 589 Pfam PF00005 ABC transporter 359 508 9.2E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_07180 c4d9bfda6dce3cb50974e435998ddecb 273 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_07180 c4d9bfda6dce3cb50974e435998ddecb 273 SMART SM00382 29 226 4.5E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_07180 c4d9bfda6dce3cb50974e435998ddecb 273 Pfam PF00005 ABC transporter 21 168 1.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_07180 c4d9bfda6dce3cb50974e435998ddecb 273 Gene3D G3DSA:3.40.50.300 2 250 5.2E-69 T 12-10-2018 HW35_07180 c4d9bfda6dce3cb50974e435998ddecb 273 SUPERFAMILY SSF52540 4 230 3.3E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13335 e2f69fae155b6007ef3d88cba7ffe8e6 268 SUPERFAMILY SSF53850 1 258 5.28E-72 T 12-10-2018 HW35_13335 e2f69fae155b6007ef3d88cba7ffe8e6 268 Gene3D G3DSA:3.40.190.10 42 255 2.7E-75 T 12-10-2018 HW35_13335 e2f69fae155b6007ef3d88cba7ffe8e6 268 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 58 71 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site HW35_13335 e2f69fae155b6007ef3d88cba7ffe8e6 268 SMART SM00079 36 257 4.6E-7 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HW35_13335 e2f69fae155b6007ef3d88cba7ffe8e6 268 Gene3D G3DSA:3.40.190.10 120 218 2.7E-75 T 12-10-2018 HW35_13335 e2f69fae155b6007ef3d88cba7ffe8e6 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 256 7.4E-65 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_13335 e2f69fae155b6007ef3d88cba7ffe8e6 268 SMART SM00062 36 258 2.4E-68 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_11770 76387ab48509309326016d440c1dbd46 668 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 314 3.0E-133 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 HW35_11770 76387ab48509309326016d440c1dbd46 668 Gene3D G3DSA:1.10.287.610 1 72 2.7E-28 T 12-10-2018 HW35_11770 76387ab48509309326016d440c1dbd46 668 Pfam PF14520 Helix-hairpin-helix domain 441 494 1.5E-4 T 12-10-2018 HW35_11770 76387ab48509309326016d440c1dbd46 668 Gene3D G3DSA:1.10.150.20 427 499 1.3E-31 T 12-10-2018 HW35_11770 76387ab48509309326016d440c1dbd46 668 Hamap MF_01588 DNA ligase [ligA]. 4 666 54.696 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HW35_11770 76387ab48509309326016d440c1dbd46 668 SMART SM00532 5 443 1.5E-293 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 HW35_11770 76387ab48509309326016d440c1dbd46 668 Gene3D G3DSA:3.40.50.10190 589 668 5.3E-26 T 12-10-2018 IPR036420 BRCT domain superfamily HW35_11770 76387ab48509309326016d440c1dbd46 668 SMART SM00292 592 668 1.8E-14 T 12-10-2018 IPR001357 BRCT domain HW35_11770 76387ab48509309326016d440c1dbd46 668 Gene3D G3DSA:1.10.150.20 500 581 3.3E-29 T 12-10-2018 HW35_11770 76387ab48509309326016d440c1dbd46 668 Gene3D G3DSA:2.20.70.80 387 424 3.9E-12 T 12-10-2018 HW35_11770 76387ab48509309326016d440c1dbd46 668 SUPERFAMILY SSF47781 399 580 2.22E-66 T 12-10-2018 IPR010994 RuvA domain 2-like HW35_11770 76387ab48509309326016d440c1dbd46 668 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 593 664 9.0E-17 T 12-10-2018 IPR001357 BRCT domain HW35_11770 76387ab48509309326016d440c1dbd46 668 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 327 342 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site HW35_11770 76387ab48509309326016d440c1dbd46 668 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site HW35_11770 76387ab48509309326016d440c1dbd46 668 Gene3D G3DSA:2.40.50.140 314 386 1.1E-30 T 12-10-2018 HW35_11770 76387ab48509309326016d440c1dbd46 668 SUPERFAMILY SSF50249 313 395 1.28E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_11770 76387ab48509309326016d440c1dbd46 668 SMART SM00278 475 494 3.5 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HW35_11770 76387ab48509309326016d440c1dbd46 668 SMART SM00278 539 558 1.2 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HW35_11770 76387ab48509309326016d440c1dbd46 668 SMART SM00278 441 460 5.4 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HW35_11770 76387ab48509309326016d440c1dbd46 668 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 662 8.1E-284 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HW35_11770 76387ab48509309326016d440c1dbd46 668 PIRSF PIRSF001604 1 668 2.4E-268 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HW35_11770 76387ab48509309326016d440c1dbd46 668 Gene3D G3DSA:3.30.470.90 73 313 1.4E-104 T 12-10-2018 HW35_11770 76387ab48509309326016d440c1dbd46 668 SUPERFAMILY SSF52113 590 666 3.63E-21 T 12-10-2018 IPR036420 BRCT domain superfamily HW35_11770 76387ab48509309326016d440c1dbd46 668 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 403 429 2.2E-11 T 12-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 HW35_11770 76387ab48509309326016d440c1dbd46 668 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 318 394 5.1E-34 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 HW35_11770 76387ab48509309326016d440c1dbd46 668 SUPERFAMILY SSF56091 2 312 1.17E-125 T 12-10-2018 HW35_11770 76387ab48509309326016d440c1dbd46 668 Pfam PF12826 Helix-hairpin-helix motif 505 568 1.4E-24 T 12-10-2018 HW35_09575 511dd648688e1bf6ad651d4ea9242890 528 Gene3D G3DSA:3.20.20.70 151 516 3.1E-88 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_09575 511dd648688e1bf6ad651d4ea9242890 528 SUPERFAMILY SSF51395 10 515 4.1E-96 T 12-10-2018 HW35_09575 511dd648688e1bf6ad651d4ea9242890 528 Pfam PF01645 Conserved region in glutamate synthase 145 489 2.2E-86 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 HW35_09575 511dd648688e1bf6ad651d4ea9242890 528 PIRSF PIRSF006429 2 528 1.1E-143 T 12-10-2018 IPR024188 Glutamate synthase large subunit-like protein HW35_17585 5d7fb7cf0ab6bce0496a25981183e0cb 307 Gene3D G3DSA:3.50.30.60 168 301 1.0E-41 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily HW35_17585 5d7fb7cf0ab6bce0496a25981183e0cb 307 SUPERFAMILY SSF141986 146 298 1.57E-41 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily HW35_17585 5d7fb7cf0ab6bce0496a25981183e0cb 307 PIRSF PIRSF028757 3 306 2.7E-93 T 12-10-2018 IPR003507 Peptidase family S66 HW35_17585 5d7fb7cf0ab6bce0496a25981183e0cb 307 Pfam PF02016 LD-carboxypeptidase 15 292 6.5E-82 T 12-10-2018 IPR003507 Peptidase family S66 HW35_17585 5d7fb7cf0ab6bce0496a25981183e0cb 307 SUPERFAMILY SSF52317 3 165 5.49E-51 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_17585 5d7fb7cf0ab6bce0496a25981183e0cb 307 Gene3D G3DSA:3.40.50.10740 3 161 4.6E-57 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal HW35_08005 954a4209293a339c3b76f111ccf15e3c 235 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 1 235 59.547 T 12-10-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 HW35_08005 954a4209293a339c3b76f111ccf15e3c 235 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 58 222 1.3E-62 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 HW35_08005 954a4209293a339c3b76f111ccf15e3c 235 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 54 227 5.4E-62 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 HW35_09475 d9c9061c110e49248ff7536ac02e1137 622 Gene3D G3DSA:2.60.40.420 499 619 9.4E-32 T 12-10-2018 IPR008972 Cupredoxin HW35_09475 d9c9061c110e49248ff7536ac02e1137 622 Gene3D G3DSA:2.130.10.10 43 498 2.2E-166 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 HW35_09475 d9c9061c110e49248ff7536ac02e1137 622 TIGRFAM TIGR04246 nitrous_NosZ_Gp: nitrous-oxide reductase, Sec-dependent 42 620 4.3E-273 T 12-10-2018 IPR026468 Nitrous-oxide reductase, Sec-dependent HW35_09475 d9c9061c110e49248ff7536ac02e1137 622 SUPERFAMILY SSF50974 45 491 1.7E-86 T 12-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 HW35_09475 d9c9061c110e49248ff7536ac02e1137 622 Pfam PF13473 Cupredoxin-like domain 539 606 2.2E-8 T 12-10-2018 IPR028096 EfeO-type cupredoxin-like domain HW35_09475 d9c9061c110e49248ff7536ac02e1137 622 SUPERFAMILY SSF49503 484 620 1.21E-25 T 12-10-2018 IPR008972 Cupredoxin HW35_03060 6fd9469fd3e6ec753bfa0443430fca12 414 SUPERFAMILY SSF81442 54 139 3.92E-8 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_12900 7b94b2bb5e4c61377a77a7cf5cf742de 134 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 131 7.4E-54 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 HW35_12900 7b94b2bb5e4c61377a77a7cf5cf742de 134 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 4.2E-40 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 HW35_12900 7b94b2bb5e4c61377a77a7cf5cf742de 134 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 95 113 - T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 HW35_12900 7b94b2bb5e4c61377a77a7cf5cf742de 134 SUPERFAMILY SSF111038 2 131 1.44E-47 T 12-10-2018 IPR035917 YjbQ-like superfamily HW35_12900 7b94b2bb5e4c61377a77a7cf5cf742de 134 Gene3D G3DSA:2.60.120.460 1 133 9.8E-56 T 12-10-2018 IPR035917 YjbQ-like superfamily HW35_12900 7b94b2bb5e4c61377a77a7cf5cf742de 134 PIRSF PIRSF004681 1 133 4.5E-39 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 HW35_15455 72084f4221d5f9c31329399e7b80e9bf 118 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 5 118 2.8E-47 T 12-10-2018 IPR014204 Sporulation stage V, protein AE HW35_15455 72084f4221d5f9c31329399e7b80e9bf 118 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 5 112 2.4E-38 T 12-10-2018 IPR005562 SpoVA HW35_09920 9eb4bd706ddd9ba93cc4a8b22aa3339a 283 Pfam PF08535 KorB domain 136 174 3.8E-5 T 12-10-2018 IPR013741 Repressor KorB domain HW35_09920 9eb4bd706ddd9ba93cc4a8b22aa3339a 283 Gene3D G3DSA:1.10.10.2830 100 214 1.0E-39 T 12-10-2018 HW35_09920 9eb4bd706ddd9ba93cc4a8b22aa3339a 283 SMART SM00470 24 113 2.0E-34 T 12-10-2018 IPR003115 ParB/Sulfiredoxin HW35_09920 9eb4bd706ddd9ba93cc4a8b22aa3339a 283 SUPERFAMILY SSF110849 24 115 8.11E-29 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily HW35_09920 9eb4bd706ddd9ba93cc4a8b22aa3339a 283 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 20 198 5.5E-65 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 HW35_09920 9eb4bd706ddd9ba93cc4a8b22aa3339a 283 Gene3D G3DSA:3.90.1530.30 37 99 1.9E-26 T 12-10-2018 HW35_09920 9eb4bd706ddd9ba93cc4a8b22aa3339a 283 Pfam PF02195 ParB-like nuclease domain 25 112 1.7E-28 T 12-10-2018 IPR003115 ParB/Sulfiredoxin HW35_09920 9eb4bd706ddd9ba93cc4a8b22aa3339a 283 SUPERFAMILY SSF109709 105 216 3.92E-36 T 12-10-2018 HW35_12535 07d52551648bef260575d47feaeac683 340 Gene3D G3DSA:3.40.50.720 5 321 3.2E-109 T 12-10-2018 HW35_12535 07d52551648bef260575d47feaeac683 340 SUPERFAMILY SSF55347 127 290 4.45E-38 T 12-10-2018 HW35_12535 07d52551648bef260575d47feaeac683 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 122 3.6E-26 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 HW35_12535 07d52551648bef260575d47feaeac683 340 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 3 330 5.9E-143 T 12-10-2018 IPR030827 Inositol 2-dehydrogenase HW35_12535 07d52551648bef260575d47feaeac683 340 SUPERFAMILY SSF51735 3 150 1.45E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_12535 07d52551648bef260575d47feaeac683 340 Gene3D G3DSA:3.30.360.10 141 271 3.2E-109 T 12-10-2018 HW35_12535 07d52551648bef260575d47feaeac683 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 233 2.0E-7 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 HW35_14685 663d7a877b0182b54a013b7f6e0e4359 307 SUPERFAMILY SSF55120 80 294 5.28E-66 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_14685 663d7a877b0182b54a013b7f6e0e4359 307 Gene3D G3DSA:3.30.2350.10 80 292 3.3E-67 T 12-10-2018 HW35_14685 663d7a877b0182b54a013b7f6e0e4359 307 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_14685 663d7a877b0182b54a013b7f6e0e4359 307 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 18 292 2.0E-71 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_14685 663d7a877b0182b54a013b7f6e0e4359 307 Pfam PF00849 RNA pseudouridylate synthase 94 248 1.6E-34 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 Gene3D G3DSA:3.90.740.10 193 397 1.1E-265 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 SUPERFAMILY SSF50677 201 392 1.78E-63 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 Pfam PF06827 Zinc finger found in FPG and IleRS 885 913 2.3E-8 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 1.5E-32 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 1.5E-32 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 518 531 1.5E-32 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 390 405 1.5E-32 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 552 561 1.5E-32 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 Pfam PF08264 Anticodon-binding domain of tRNA 676 830 1.5E-30 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 831 0.0 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 SUPERFAMILY SSF52374 1 639 1.35E-155 T 12-10-2018 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 Gene3D G3DSA:3.40.50.620 24 620 1.1E-265 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 Gene3D G3DSA:1.10.730.20 631 918 1.8E-106 T 12-10-2018 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 21.266 T 12-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 632 1.7E-224 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_16435 aecd305e8c10dd6c3034e9587930c199 923 SUPERFAMILY SSF47323 643 917 3.55E-83 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_05615 487da83e61b455ddc3c7d034dd07095f 206 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 199 28.573 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 HW35_05615 487da83e61b455ddc3c7d034dd07095f 206 SUPERFAMILY SSF52540 1 194 8.63E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05615 487da83e61b455ddc3c7d034dd07095f 206 Pfam PF01121 Dephospho-CoA kinase 3 182 3.4E-63 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 HW35_05615 487da83e61b455ddc3c7d034dd07095f 206 Gene3D G3DSA:3.40.50.300 1 201 1.4E-78 T 12-10-2018 HW35_05615 487da83e61b455ddc3c7d034dd07095f 206 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 4.3E-63 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 HW35_03085 36cfc6e803ac5baf81ef47d78562cb3a 185 Hamap MF_01575 UPF0398 protein . 1 177 36.071 T 12-10-2018 IPR010697 Protein of unknown function DUF1273 HW35_03085 36cfc6e803ac5baf81ef47d78562cb3a 185 Pfam PF06908 Protein of unknown function (DUF1273) 4 171 1.2E-69 T 12-10-2018 IPR010697 Protein of unknown function DUF1273 HW35_03085 36cfc6e803ac5baf81ef47d78562cb3a 185 Gene3D G3DSA:3.40.50.450 1 180 3.6E-69 T 12-10-2018 HW35_03085 36cfc6e803ac5baf81ef47d78562cb3a 185 PIRSF PIRSF021290 1 179 1.2E-70 T 12-10-2018 IPR010697 Protein of unknown function DUF1273 HW35_03085 36cfc6e803ac5baf81ef47d78562cb3a 185 SUPERFAMILY SSF102405 2 177 8.97E-66 T 12-10-2018 HW35_05715 35b433950b22da74c0302065623287e2 1120 Pfam PF02811 PHP domain 5 167 6.2E-38 T 12-10-2018 IPR004013 PHP domain GO:0003824 HW35_05715 35b433950b22da74c0302065623287e2 1120 Gene3D G3DSA:3.20.20.140 1 264 1.4E-88 T 12-10-2018 HW35_05715 35b433950b22da74c0302065623287e2 1120 Pfam PF14579 Helix-hairpin-helix motif 782 867 6.6E-25 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05715 35b433950b22da74c0302065623287e2 1120 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 994 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05715 35b433950b22da74c0302065623287e2 1120 Gene3D G3DSA:1.10.10.1600 418 495 7.3E-23 T 12-10-2018 HW35_05715 35b433950b22da74c0302065623287e2 1120 SMART SM00481 4 71 6.3E-20 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HW35_05715 35b433950b22da74c0302065623287e2 1120 SUPERFAMILY SSF89550 3 257 3.53E-19 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HW35_05715 35b433950b22da74c0302065623287e2 1120 Gene3D G3DSA:1.10.150.870 756 857 1.6E-8 T 12-10-2018 HW35_05715 35b433950b22da74c0302065623287e2 1120 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 285 707 1.1E-178 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_14125 bacee484fd2bbcfe1cbca970edc5a101 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 316 1.9E-27 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HW35_14125 bacee484fd2bbcfe1cbca970edc5a101 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 345 4.2E-138 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HW35_14125 bacee484fd2bbcfe1cbca970edc5a101 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 339 43.689 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HW35_14125 bacee484fd2bbcfe1cbca970edc5a101 345 Gene3D G3DSA:3.40.50.720 3 331 1.8E-130 T 12-10-2018 HW35_14125 bacee484fd2bbcfe1cbca970edc5a101 345 SUPERFAMILY SSF51735 2 173 9.16E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_14125 bacee484fd2bbcfe1cbca970edc5a101 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 140 1.1E-30 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HW35_14125 bacee484fd2bbcfe1cbca970edc5a101 345 SUPERFAMILY SSF55347 149 313 1.23E-58 T 12-10-2018 HW35_14125 bacee484fd2bbcfe1cbca970edc5a101 345 SMART SM00859 2 141 2.9E-46 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HW35_14125 bacee484fd2bbcfe1cbca970edc5a101 345 Gene3D G3DSA:3.30.360.10 147 313 1.8E-130 T 12-10-2018 HW35_14125 bacee484fd2bbcfe1cbca970edc5a101 345 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 12-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HW35_08525 3b5fae7375ef0ba6152e6e1a7629443b 308 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_08525 3b5fae7375ef0ba6152e6e1a7629443b 308 SUPERFAMILY SSF52540 3 219 6.44E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_08525 3b5fae7375ef0ba6152e6e1a7629443b 308 Gene3D G3DSA:3.40.50.300 1 235 7.3E-68 T 12-10-2018 HW35_08525 3b5fae7375ef0ba6152e6e1a7629443b 308 SMART SM00382 28 206 4.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_08525 3b5fae7375ef0ba6152e6e1a7629443b 308 Pfam PF00005 ABC transporter 20 157 3.4E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_03355 75b3d2c8545c982706bc5b141a14d5f0 234 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 HW35_03355 75b3d2c8545c982706bc5b141a14d5f0 234 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 HW35_03355 75b3d2c8545c982706bc5b141a14d5f0 234 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 233 36.576 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 HW35_03355 75b3d2c8545c982706bc5b141a14d5f0 234 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 3 233 5.9E-136 T 12-10-2018 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 HW35_03355 75b3d2c8545c982706bc5b141a14d5f0 234 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 233 5.3E-102 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 HW35_03355 75b3d2c8545c982706bc5b141a14d5f0 234 Gene3D G3DSA:3.40.50.150 15 234 2.8E-68 T 12-10-2018 HW35_03355 75b3d2c8545c982706bc5b141a14d5f0 234 SUPERFAMILY SSF53335 3 227 5.88E-52 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_03355 75b3d2c8545c982706bc5b141a14d5f0 234 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 233 6.5E-81 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.281 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 4.2E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 4.2E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 4.2E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 4.2E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 4.2E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 Pfam PF00574 Clp protease 13 192 1.2E-87 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 Gene3D G3DSA:3.90.226.10 1 196 9.7E-85 T 12-10-2018 HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 5.5E-108 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 12-10-2018 IPR033135 ClpP, histidine active site HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 SUPERFAMILY SSF52096 10 194 9.54E-75 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_07575 58ce954670d9b57bf6ff9106f91ecf12 197 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 12-10-2018 IPR018215 ClpP, Ser active site HW35_10735 c6cd7e1773a56676e0defbd14603876a 92 SUPERFAMILY SSF54570 3 84 3.66E-36 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10735 c6cd7e1773a56676e0defbd14603876a 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.976 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10735 c6cd7e1773a56676e0defbd14603876a 92 Pfam PF00203 Ribosomal protein S19 3 83 1.8E-37 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10735 c6cd7e1773a56676e0defbd14603876a 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 7.7E-49 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 HW35_10735 c6cd7e1773a56676e0defbd14603876a 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 6.3E-25 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10735 c6cd7e1773a56676e0defbd14603876a 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 6.3E-25 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10735 c6cd7e1773a56676e0defbd14603876a 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 6.3E-25 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10735 c6cd7e1773a56676e0defbd14603876a 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10735 c6cd7e1773a56676e0defbd14603876a 92 PIRSF PIRSF002144 1 92 2.2E-33 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10735 c6cd7e1773a56676e0defbd14603876a 92 Gene3D G3DSA:3.30.860.10 1 92 8.8E-42 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 SUPERFAMILY SSF54791 556 641 7.96E-24 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 SMART SM00322 553 618 3.3E-13 T 12-10-2018 IPR004087 K Homology domain GO:0003676 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 693 0.0 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Pfam PF00575 S1 RNA binding domain 622 691 2.8E-19 T 12-10-2018 IPR003029 S1 domain GO:0003676 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Pfam PF00013 KH domain 557 615 1.6E-9 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 2.9E-15 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Pfam PF03725 3' exoribonuclease family, domain 2 460 528 1.5E-6 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 241 321 1.6E-15 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 SUPERFAMILY SSF55666 145 236 6.81E-31 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 31.167 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 SUPERFAMILY SSF55666 451 550 1.24E-28 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 SUPERFAMILY SSF54211 293 489 1.72E-49 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 1.6E-21 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 9.0E-19 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Gene3D G3DSA:3.30.230.70 1 230 8.9E-86 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 SUPERFAMILY SSF50249 622 704 4.62E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 PIRSF PIRSF005499 2 705 2.4E-304 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 SUPERFAMILY SSF54211 4 144 2.23E-50 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 SMART SM00316 621 691 1.6E-24 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Gene3D G3DSA:2.40.50.140 623 694 3.3E-26 T 12-10-2018 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Gene3D G3DSA:3.30.1370.10 551 622 2.3E-20 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 HW35_16860 80cff72abdd81037fc92d99093d92a3b 705 Gene3D G3DSA:3.30.230.70 233 550 2.2E-120 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_06765 878f83041624542ccddbb5dbd0400fb7 339 Gene3D G3DSA:3.90.550.10 2 210 4.2E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_06765 878f83041624542ccddbb5dbd0400fb7 339 Pfam PF00535 Glycosyl transferase family 2 7 177 1.7E-25 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HW35_06765 878f83041624542ccddbb5dbd0400fb7 339 SUPERFAMILY SSF53448 2 262 7.31E-27 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_11230 b4adefedbc34869d2d78168d87e654d8 143 SMART SM00347 21 124 4.0E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_11230 b4adefedbc34869d2d78168d87e654d8 143 SUPERFAMILY SSF46785 20 140 7.81E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_11230 b4adefedbc34869d2d78168d87e654d8 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 5.4E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_11230 b4adefedbc34869d2d78168d87e654d8 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 5.4E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_11230 b4adefedbc34869d2d78168d87e654d8 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 5.4E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_11230 b4adefedbc34869d2d78168d87e654d8 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 5.4E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_11230 b4adefedbc34869d2d78168d87e654d8 143 Pfam PF13463 Winged helix DNA-binding domain 30 97 4.3E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_11230 b4adefedbc34869d2d78168d87e654d8 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 63 97 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site HW35_11230 b4adefedbc34869d2d78168d87e654d8 143 Gene3D G3DSA:1.10.10.10 2 139 2.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_15955 b12c60951c74a39877cab7f562527880 144 Gene3D G3DSA:3.30.310.120 51 142 8.0E-31 T 12-10-2018 HW35_15955 b12c60951c74a39877cab7f562527880 144 Gene3D G3DSA:1.20.5.850 2 50 4.7E-16 T 12-10-2018 HW35_15955 b12c60951c74a39877cab7f562527880 144 SUPERFAMILY SSF111171 5 141 3.66E-42 T 12-10-2018 IPR036294 Rbstp2229-like superfamily HW35_15955 b12c60951c74a39877cab7f562527880 144 Pfam PF08968 Domain of unknown function (DUF1885) 3 142 2.2E-58 T 12-10-2018 IPR015062 Protein of unknown function DUF1885 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 1.5E-132 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 371 4.6E-165 T 12-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 SUPERFAMILY SSF48256 2 371 3.93E-138 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 Gene3D G3DSA:1.10.230.10 220 318 8.3E-130 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 Gene3D G3DSA:1.10.580.10 25 351 8.3E-130 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 ProSitePatterns PS00480 Citrate synthase signature. 254 266 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 PIRSF PIRSF001369 1 372 2.7E-158 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 PRINTS PR00143 Citrate synthase signature 304 320 2.1E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 PRINTS PR00143 Citrate synthase signature 172 187 2.1E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 PRINTS PR00143 Citrate synthase signature 123 136 2.1E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 PRINTS PR00143 Citrate synthase signature 194 222 2.1E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 PRINTS PR00143 Citrate synthase signature 247 267 2.1E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 HW35_05670 295d96003f3f79649c36ee3497a9daa9 372 PRINTS PR00143 Citrate synthase signature 324 338 2.1E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 Gene3D G3DSA:3.50.50.60 6 304 6.0E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_06920 9e93744080299bdccaddd0afd3a48610 331 Gene3D G3DSA:3.50.50.60 127 246 6.0E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_06920 9e93744080299bdccaddd0afd3a48610 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 1.8E-18 T 12-10-2018 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.8E-18 T 12-10-2018 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.8E-18 T 12-10-2018 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 202 218 3.2E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 3.2E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 3.2E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 3.2E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 65 75 3.2E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 3.2E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 Hamap MF_01685 Ferredoxin--NADP reductase. 6 328 44.711 T 12-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 HW35_06920 9e93744080299bdccaddd0afd3a48610 331 SUPERFAMILY SSF51905 7 314 1.62E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_06920 9e93744080299bdccaddd0afd3a48610 331 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 293 3.0E-30 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_07685 30c7d605edff67fa32706bed36bf607f 312 Pfam PF07670 Nucleoside recognition 176 263 4.2E-7 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HW35_07685 30c7d605edff67fa32706bed36bf607f 312 Pfam PF07670 Nucleoside recognition 18 99 1.7E-8 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 156 511 2.0E-119 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 Pfam PF01588 Putative tRNA binding domain 560 651 3.8E-28 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 522 654 1.1E-47 T 12-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 Gene3D G3DSA:2.170.220.10 117 226 2.9E-155 T 12-10-2018 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 4.6E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 4.6E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 272 4.6E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 PRINTS PR01041 Methionyl-tRNA synthetase signature 349 360 4.6E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 4.6E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 4.6E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 Pfam PF08264 Anticodon-binding domain of tRNA 386 470 1.0E-6 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 Pfam PF09334 tRNA synthetases class I (M) 156 361 3.3E-70 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 Pfam PF09334 tRNA synthetases class I (M) 6 150 8.2E-55 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 Gene3D G3DSA:3.40.50.620 6 334 2.9E-155 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_10195 65874b33786a89e1011934cf61ca62ce 654 SUPERFAMILY SSF47323 351 567 1.74E-45 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 Gene3D G3DSA:1.10.730.10 339 509 2.8E-50 T 12-10-2018 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 Gene3D G3DSA:2.40.50.140 545 654 8.3E-37 T 12-10-2018 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 Hamap MF_01228 Methionine--tRNA ligase [metG]. 2 510 52.297 T 12-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 SUPERFAMILY SSF52374 3 348 1.37E-120 T 12-10-2018 HW35_10195 65874b33786a89e1011934cf61ca62ce 654 SUPERFAMILY SSF50249 553 653 2.03E-33 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 Hamap MF_00335 Ribonuclease Y [rny]. 4 519 26.053 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 SUPERFAMILY SSF54791 207 303 1.39E-16 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 Gene3D G3DSA:3.30.1370.10 207 303 3.6E-9 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 SMART SM00471 331 437 1.8E-14 T 12-10-2018 IPR003607 HD/PDEase domain HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 7 519 2.3E-247 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 SUPERFAMILY SSF109604 315 466 4.94E-30 T 12-10-2018 HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 TIGRFAM TIGR00277 HDIG: HDIG domain 331 408 1.7E-25 T 12-10-2018 IPR006675 HDIG domain HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 Pfam PF12072 Domain of unknown function (DUF3552) 5 204 6.9E-79 T 12-10-2018 IPR022711 Ribonuclease Y, N-terminal HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 Pfam PF00013 KH domain 212 269 2.4E-6 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 Gene3D G3DSA:1.10.3210.10 318 471 4.6E-19 T 12-10-2018 HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 Pfam PF01966 HD domain 336 427 2.7E-18 T 12-10-2018 IPR006674 HD domain HW35_16995 45d8c76615b02c5dfccdc78c9ad5adab 519 SMART SM00322 207 274 1.2E-6 T 12-10-2018 IPR004087 K Homology domain GO:0003676 HW35_05425 fc252149958dde852f9b3dc5988c5df3 202 SUPERFAMILY SSF81343 4 201 7.59E-60 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05425 fc252149958dde852f9b3dc5988c5df3 202 Gene3D G3DSA:1.20.1300.10 2 202 6.4E-43 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05425 fc252149958dde852f9b3dc5988c5df3 202 PIRSF PIRSF000170 1 202 3.6E-98 T 12-10-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute HW35_05425 fc252149958dde852f9b3dc5988c5df3 202 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 92 193 4.7E-12 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05425 fc252149958dde852f9b3dc5988c5df3 202 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 6 202 2.5E-51 T 12-10-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit HW35_09790 f7cea33c806eae43c11122c93776f1c2 265 Gene3D G3DSA:3.10.450.660 47 253 1.1E-67 T 12-10-2018 HW35_09790 f7cea33c806eae43c11122c93776f1c2 265 Gene3D G3DSA:3.30.310.160 70 182 1.1E-67 T 12-10-2018 HW35_09790 f7cea33c806eae43c11122c93776f1c2 265 Pfam PF09648 YycH protein 39 249 2.8E-57 T 12-10-2018 IPR018604 Regulatory protein YycH-like GO:0016021 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 Gene3D G3DSA:1.20.1640.10 249 421 3.5E-14 T 12-10-2018 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 Gene3D G3DSA:1.20.1640.10 425 472 3.5E-14 T 12-10-2018 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 476 720 3.1E-69 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 Gene3D G3DSA:3.30.70.3400 34 122 4.4E-23 T 12-10-2018 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 503 717 3.4E-54 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 186 398 3.4E-56 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 Gene3D G3DSA:3.30.70.1320 207 245 3.5E-14 T 12-10-2018 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 SUPERFAMILY SSF82866 136 410 1.83E-39 T 12-10-2018 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 447 731 26.756 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 SUPERFAMILY SSF82866 555 733 1.96E-35 T 12-10-2018 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 419 33.382 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 Pfam PF07549 SecD/SecF GG Motif 470 494 1.0E-4 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 Gene3D G3DSA:1.20.1640.10 543 750 6.9E-8 T 12-10-2018 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 34 405 2.5E-108 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 Pfam PF02355 Protein export membrane protein 551 729 8.6E-65 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 Pfam PF02355 Protein export membrane protein 240 409 3.4E-14 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 PRINTS PR01755 Bacterial translocase SecF protein signature 474 489 1.7E-24 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 PRINTS PR01755 Bacterial translocase SecF protein signature 584 598 1.7E-24 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 PRINTS PR01755 Bacterial translocase SecF protein signature 632 650 1.7E-24 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HW35_04920 e563f6ad13c7053cf19227ba8704c36d 753 PRINTS PR01755 Bacterial translocase SecF protein signature 668 683 1.7E-24 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 Gene3D G3DSA:1.20.5.100 198 228 1.2E-15 T 12-10-2018 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 SUPERFAMILY SSF52413 300 425 2.75E-34 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 Gene3D G3DSA:3.40.50.720 229 431 2.5E-73 T 12-10-2018 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 415 1.3E-30 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 184 1.1E-67 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 Gene3D G3DSA:3.40.50.720 1 196 7.6E-77 T 12-10-2018 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 SMART SM00984 314 415 3.6E-40 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 SUPERFAMILY SSF51735 2 190 4.61E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 SUPERFAMILY SSF48179 198 295 8.5E-31 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 PIRSF PIRSF000124 1 430 2.3E-136 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 PIRSF PIRSF500134 1 431 1.4E-162 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 411 2.8E-145 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HW35_08065 03e0686c29a96838bc56d0c507b21a95 431 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 290 1.6E-36 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 SUPERFAMILY SSF52949 10 182 8.83E-39 T 12-10-2018 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 2 499 36.397 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 Gene3D G3DSA:3.40.220.10 2 157 1.9E-43 T 12-10-2018 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 PRINTS PR00481 Cytosol aminopeptidase signature 283 304 3.2E-52 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 PRINTS PR00481 Cytosol aminopeptidase signature 261 278 3.2E-52 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 PRINTS PR00481 Cytosol aminopeptidase signature 320 341 3.2E-52 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 PRINTS PR00481 Cytosol aminopeptidase signature 370 385 3.2E-52 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 PRINTS PR00481 Cytosol aminopeptidase signature 342 362 3.2E-52 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 SUPERFAMILY SSF53187 181 495 1.63E-114 T 12-10-2018 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 346 353 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 Gene3D G3DSA:3.40.630.10 171 497 4.6E-130 T 12-10-2018 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 185 490 7.4E-120 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 HW35_06895 864e6ba44c714d7f38f811be1fc12906 502 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 18 147 2.0E-29 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 HW35_03960 55afce6a200cc131dcd03aed582924d1 297 Gene3D G3DSA:1.10.600.10 3 297 2.8E-104 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily HW35_03960 55afce6a200cc131dcd03aed582924d1 297 SUPERFAMILY SSF48576 10 272 1.98E-84 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily HW35_03960 55afce6a200cc131dcd03aed582924d1 297 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 216 228 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site HW35_03960 55afce6a200cc131dcd03aed582924d1 297 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 99 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site HW35_03960 55afce6a200cc131dcd03aed582924d1 297 Pfam PF00348 Polyprenyl synthetase 33 269 1.1E-55 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 367 2.0E-160 T 12-10-2018 IPR010162 Peptidase M20B, peptidase T-like HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 SUPERFAMILY SSF53187 5 368 1.31E-60 T 12-10-2018 HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 Pfam PF07687 Peptidase dimerisation domain 181 274 1.2E-15 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 Pfam PF01546 Peptidase family M20/M25/M40 74 368 1.5E-21 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 PIRSF PIRSF001123 91 208 7.6E-6 T 12-10-2018 IPR008007 Peptidase M42 HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 PIRSF PIRSF001123 4 83 0.036 T 12-10-2018 IPR008007 Peptidase M42 HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 PIRSF PIRSF001123 292 373 0.019 T 12-10-2018 IPR008007 Peptidase M42 HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 Gene3D G3DSA:3.40.630.10 14 363 2.9E-134 T 12-10-2018 HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 SUPERFAMILY SSF55031 180 285 9.55E-22 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 Gene3D G3DSA:3.30.70.360 177 288 2.9E-134 T 12-10-2018 HW35_03840 4fcac511ec1dfb3710d1f69b216f1c20 373 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 143 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HW35_08710 009e749b233db3108e7177947fb8d332 653 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 13 94 7.2E-32 T 12-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 HW35_08710 009e749b233db3108e7177947fb8d332 653 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 123 468 1.6E-99 T 12-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 HW35_08710 009e749b233db3108e7177947fb8d332 653 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 554 570 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_08710 009e749b233db3108e7177947fb8d332 653 Pfam PF02378 Phosphotransferase system, EIIC 138 413 1.4E-22 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HW35_08710 009e749b233db3108e7177947fb8d332 653 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 13 103 7.1E-17 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HW35_08710 009e749b233db3108e7177947fb8d332 653 SUPERFAMILY SSF55804 504 650 2.09E-41 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_08710 009e749b233db3108e7177947fb8d332 653 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 509 636 4.5E-42 T 12-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 HW35_08710 009e749b233db3108e7177947fb8d332 653 SUPERFAMILY SSF52794 10 111 7.67E-38 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_08710 009e749b233db3108e7177947fb8d332 653 Gene3D G3DSA:3.40.930.10 500 653 4.4E-46 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_08710 009e749b233db3108e7177947fb8d332 653 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 508 650 4.6E-40 T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_08710 009e749b233db3108e7177947fb8d332 653 Gene3D G3DSA:3.40.50.2300 1 110 1.1E-42 T 12-10-2018 HW35_08850 1d5be492f41974123760acd5d4a3ade4 273 Pfam PF13276 HTH-like domain 28 76 9.7E-19 T 12-10-2018 IPR025948 HTH-like domain HW35_08850 1d5be492f41974123760acd5d4a3ade4 273 SUPERFAMILY SSF53098 100 263 1.32E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_08850 1d5be492f41974123760acd5d4a3ade4 273 Gene3D G3DSA:3.30.420.10 99 271 2.2E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_08850 1d5be492f41974123760acd5d4a3ade4 273 Pfam PF00665 Integrase core domain 109 223 8.5E-24 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_09265 0309fc60f8f622d40d6e029b8e322890 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 7.9E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_09265 0309fc60f8f622d40d6e029b8e322890 212 SUPERFAMILY SSF48498 92 205 1.73E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily HW35_09265 0309fc60f8f622d40d6e029b8e322890 212 Gene3D G3DSA:1.10.10.60 17 59 1.3E-15 T 12-10-2018 HW35_09265 0309fc60f8f622d40d6e029b8e322890 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 3.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_09265 0309fc60f8f622d40d6e029b8e322890 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 3.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_09265 0309fc60f8f622d40d6e029b8e322890 212 Gene3D G3DSA:1.10.357.10 61 206 1.7E-16 T 12-10-2018 HW35_09265 0309fc60f8f622d40d6e029b8e322890 212 SUPERFAMILY SSF46689 17 91 5.49E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_15545 b9d20e9b45b063f85daf02f341a8c9f5 227 Gene3D G3DSA:3.40.50.300 1 226 7.0E-70 T 12-10-2018 HW35_15545 b9d20e9b45b063f85daf02f341a8c9f5 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_15545 b9d20e9b45b063f85daf02f341a8c9f5 227 Pfam PF00005 ABC transporter 21 169 2.6E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_15545 b9d20e9b45b063f85daf02f341a8c9f5 227 SUPERFAMILY SSF52540 1 221 1.68E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15545 b9d20e9b45b063f85daf02f341a8c9f5 227 SMART SM00382 30 217 3.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_04300 bb8ab5cc6a50afff7146c03bf9289afe 292 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 22 289 1.0E-82 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 HW35_04300 bb8ab5cc6a50afff7146c03bf9289afe 292 SUPERFAMILY SSF161098 31 277 1.31E-38 T 12-10-2018 IPR035906 MetI-like superfamily HW35_04300 bb8ab5cc6a50afff7146c03bf9289afe 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 285 1.6E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_04300 bb8ab5cc6a50afff7146c03bf9289afe 292 Gene3D G3DSA:1.10.3720.10 68 291 2.6E-34 T 12-10-2018 IPR035906 MetI-like superfamily HW35_04725 1a9fffafa5185a7d12764a8db141577b 582 Gene3D G3DSA:3.90.1310.30 49 231 8.0E-13 T 12-10-2018 HW35_04725 1a9fffafa5185a7d12764a8db141577b 582 SUPERFAMILY SSF56601 186 577 1.88E-56 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_04725 1a9fffafa5185a7d12764a8db141577b 582 Pfam PF00905 Penicillin binding protein transpeptidase domain 261 567 2.5E-46 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HW35_04725 1a9fffafa5185a7d12764a8db141577b 582 SUPERFAMILY SSF56519 48 219 1.57E-18 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 HW35_04725 1a9fffafa5185a7d12764a8db141577b 582 Gene3D G3DSA:3.40.710.10 235 581 6.3E-68 T 12-10-2018 HW35_04725 1a9fffafa5185a7d12764a8db141577b 582 Pfam PF03717 Penicillin-binding Protein dimerisation domain 57 212 1.7E-6 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 Hamap MF_00384 Homoserine kinase [thrB]. 9 298 29.183 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 TIGRFAM TIGR00191 thrB: homoserine kinase 7 298 3.6E-83 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 89 100 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 Pfam PF08544 GHMP kinases C terminal 205 281 6.6E-12 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 Gene3D G3DSA:3.30.70.890 168 288 7.6E-35 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 SUPERFAMILY SSF55060 164 284 1.42E-31 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 Gene3D G3DSA:3.30.230.10 6 167 3.9E-47 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 PIRSF PIRSF000676 3 300 3.5E-89 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 SUPERFAMILY SSF54211 7 151 7.59E-30 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 PRINTS PR00958 Homoserine kinase signature 130 143 6.5E-36 T 12-10-2018 HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 PRINTS PR00958 Homoserine kinase signature 14 29 6.5E-36 T 12-10-2018 HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 PRINTS PR00958 Homoserine kinase signature 168 185 6.5E-36 T 12-10-2018 HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 PRINTS PR00958 Homoserine kinase signature 96 111 6.5E-36 T 12-10-2018 HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 PRINTS PR00958 Homoserine kinase signature 248 263 6.5E-36 T 12-10-2018 HW35_06590 11cf8fd2dc04779d4c97301836c7b6da 305 Pfam PF00288 GHMP kinases N terminal domain 83 143 3.9E-11 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 HW35_04520 ac2fb9ca40b032c9a05c7ec4597e1608 457 Gene3D G3DSA:3.80.30.20 140 375 6.3E-86 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HW35_04520 ac2fb9ca40b032c9a05c7ec4597e1608 457 Pfam PF04055 Radical SAM superfamily 149 319 5.1E-28 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_04520 ac2fb9ca40b032c9a05c7ec4597e1608 457 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 HW35_04520 ac2fb9ca40b032c9a05c7ec4597e1608 457 SMART SM00729 143 361 4.0E-60 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HW35_04520 ac2fb9ca40b032c9a05c7ec4597e1608 457 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 423 3.5E-144 T 12-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 HW35_04520 ac2fb9ca40b032c9a05c7ec4597e1608 457 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 1.2E-26 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 HW35_04520 ac2fb9ca40b032c9a05c7ec4597e1608 457 Gene3D G3DSA:3.40.50.12160 3 134 1.0E-24 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily HW35_04520 ac2fb9ca40b032c9a05c7ec4597e1608 457 Pfam PF01938 TRAM domain 375 434 1.6E-7 T 12-10-2018 IPR002792 TRAM domain HW35_04520 ac2fb9ca40b032c9a05c7ec4597e1608 457 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 431 1.4E-149 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 HW35_04520 ac2fb9ca40b032c9a05c7ec4597e1608 457 SUPERFAMILY SSF102114 118 363 1.83E-57 T 12-10-2018 HW35_12090 74edac5d25416ffe44efa47dc3ce9172 494 SMART SM00304 198 251 1.5E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_12090 74edac5d25416ffe44efa47dc3ce9172 494 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 479 2.3E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_12090 74edac5d25416ffe44efa47dc3ce9172 494 Gene3D G3DSA:1.20.1480.50 162 257 8.0E-13 T 12-10-2018 HW35_12090 74edac5d25416ffe44efa47dc3ce9172 494 SMART SM00387 356 481 7.3E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_12090 74edac5d25416ffe44efa47dc3ce9172 494 Pfam PF00672 HAMP domain 200 248 3.6E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_12090 74edac5d25416ffe44efa47dc3ce9172 494 SUPERFAMILY SSF55874 322 478 3.27E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_12090 74edac5d25416ffe44efa47dc3ce9172 494 Gene3D G3DSA:3.30.565.10 335 483 9.1E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_12090 74edac5d25416ffe44efa47dc3ce9172 494 SUPERFAMILY SSF158472 200 249 1.18E-8 T 12-10-2018 HW35_12090 74edac5d25416ffe44efa47dc3ce9172 494 Pfam PF06580 Histidine kinase 266 345 4.2E-24 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 HW35_06425 0022f17d15f99f49de97946e84c5e485 380 SUPERFAMILY SSF51161 286 360 2.51E-14 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily HW35_06425 0022f17d15f99f49de97946e84c5e485 380 Gene3D G3DSA:2.160.10.10 275 379 4.2E-28 T 12-10-2018 HW35_06425 0022f17d15f99f49de97946e84c5e485 380 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 190 200 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 HW35_06425 0022f17d15f99f49de97946e84c5e485 380 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 360 2.5E-149 T 12-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 HW35_06425 0022f17d15f99f49de97946e84c5e485 380 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 375 49.541 T 12-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 HW35_06425 0022f17d15f99f49de97946e84c5e485 380 TIGRFAM TIGR02092 glgD: glucose-1-phosphate adenylyltransferase, GlgD subunit 5 373 6.5E-71 T 12-10-2018 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 HW35_06425 0022f17d15f99f49de97946e84c5e485 380 SUPERFAMILY SSF53448 4 340 2.82E-88 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_06425 0022f17d15f99f49de97946e84c5e485 380 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 99 107 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 HW35_06425 0022f17d15f99f49de97946e84c5e485 380 Pfam PF00483 Nucleotidyl transferase 8 261 4.4E-74 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HW35_06425 0022f17d15f99f49de97946e84c5e485 380 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 HW35_06425 0022f17d15f99f49de97946e84c5e485 380 Gene3D G3DSA:3.90.550.10 2 274 1.1E-96 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_12325 f2481f32b7c95ecd239b0a8b0b34338e 196 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 HW35_12325 f2481f32b7c95ecd239b0a8b0b34338e 196 Pfam PF00625 Guanylate kinase 8 185 1.4E-23 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HW35_12325 f2481f32b7c95ecd239b0a8b0b34338e 196 Gene3D G3DSA:3.30.63.10 38 97 1.4E-35 T 12-10-2018 HW35_12325 f2481f32b7c95ecd239b0a8b0b34338e 196 SUPERFAMILY SSF52540 8 186 4.61E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12325 f2481f32b7c95ecd239b0a8b0b34338e 196 Gene3D G3DSA:3.40.50.300 12 183 1.4E-35 T 12-10-2018 HW35_12325 f2481f32b7c95ecd239b0a8b0b34338e 196 SMART SM00072 7 191 2.9E-17 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HW35_14435 81945dac2ecde5d2e0948fcf4b7e07d4 187 Gene3D G3DSA:1.10.10.60 150 183 1.9E-6 T 12-10-2018 HW35_14435 81945dac2ecde5d2e0948fcf4b7e07d4 187 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 12-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 HW35_14435 81945dac2ecde5d2e0948fcf4b7e07d4 187 SMART SM00857 3 137 1.3E-56 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HW35_14435 81945dac2ecde5d2e0948fcf4b7e07d4 187 SUPERFAMILY SSF46689 140 180 2.94E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_14435 81945dac2ecde5d2e0948fcf4b7e07d4 187 Gene3D G3DSA:3.40.50.1390 2 126 1.5E-46 T 12-10-2018 HW35_14435 81945dac2ecde5d2e0948fcf4b7e07d4 187 Pfam PF00239 Resolvase, N terminal domain 4 135 1.3E-42 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HW35_14435 81945dac2ecde5d2e0948fcf4b7e07d4 187 SUPERFAMILY SSF53041 1 134 1.44E-44 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 HW35_14460 077c07745b670f2dee419ab0f08c881d 73 Gene3D G3DSA:1.10.260.40 2 69 6.5E-13 T 12-10-2018 HW35_14460 077c07745b670f2dee419ab0f08c881d 73 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 2.3E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_14460 077c07745b670f2dee419ab0f08c881d 73 SUPERFAMILY SSF47413 1 58 4.22E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_14460 077c07745b670f2dee419ab0f08c881d 73 SMART SM00530 6 62 9.0E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_13620 feb973125e1f1278a6d7c49bbeeb0f18 447 Pfam PF01943 Polysaccharide biosynthesis protein 6 295 1.3E-21 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HW35_13620 feb973125e1f1278a6d7c49bbeeb0f18 447 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 347 438 3.0E-8 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 PRINTS PR00086 L-lactate dehydrogenase signature 8 32 9.2E-50 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 9.2E-50 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 9.2E-50 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 9.2E-50 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 9.2E-50 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 11 303 9.3E-129 T 12-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 6 309 46.12 T 12-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 SUPERFAMILY SSF56327 147 306 6.2E-58 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 PIRSF PIRSF000102 4 308 8.7E-113 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 Gene3D G3DSA:3.90.110.10 148 307 9.7E-65 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 306 1.1E-35 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 Gene3D G3DSA:3.40.50.720 2 147 4.9E-58 T 12-10-2018 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 SUPERFAMILY SSF51735 5 146 4.91E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 8 146 2.7E-47 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_13880 7d8d7022647e09194dd405339fb44ed2 311 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 12-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 HW35_12370 d159da6072e33a6816aa255282015985 267 SUPERFAMILY SSF81606 6 266 9.02E-16 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_12370 d159da6072e33a6816aa255282015985 267 Gene3D G3DSA:3.60.40.10 1 266 3.2E-17 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_12370 d159da6072e33a6816aa255282015985 267 Pfam PF13672 Protein phosphatase 2C 11 224 1.2E-14 T 12-10-2018 HW35_01140 7781548ff4e1c247882d67883f64dd60 451 SUPERFAMILY SSF53383 19 449 7.43E-127 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_01140 7781548ff4e1c247882d67883f64dd60 451 Gene3D G3DSA:3.40.640.10 66 339 5.3E-152 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_01140 7781548ff4e1c247882d67883f64dd60 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 287 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_01140 7781548ff4e1c247882d67883f64dd60 451 Gene3D G3DSA:3.90.1150.10 15 447 5.3E-152 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_01140 7781548ff4e1c247882d67883f64dd60 451 PIRSF PIRSF000521 21 450 3.7E-41 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_01140 7781548ff4e1c247882d67883f64dd60 451 Pfam PF00202 Aminotransferase class-III 29 447 1.1E-108 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_07470 c05503edf9cffaf0d6c313938b248a90 351 SUPERFAMILY SSF51269 288 350 3.66E-20 T 12-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 HW35_07470 c05503edf9cffaf0d6c313938b248a90 351 Pfam PF08666 SAF domain 293 350 1.9E-13 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 HW35_07470 c05503edf9cffaf0d6c313938b248a90 351 SMART SM00858 292 350 5.2E-13 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 HW35_07470 c05503edf9cffaf0d6c313938b248a90 351 SUPERFAMILY SSF51569 3 302 2.32E-91 T 12-10-2018 HW35_07470 c05503edf9cffaf0d6c313938b248a90 351 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 16 344 2.5E-154 T 12-10-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 HW35_07470 c05503edf9cffaf0d6c313938b248a90 351 Pfam PF03102 NeuB family 37 277 6.8E-89 T 12-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 HW35_07470 c05503edf9cffaf0d6c313938b248a90 351 Gene3D G3DSA:3.20.20.70 3 277 1.8E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_07470 c05503edf9cffaf0d6c313938b248a90 351 Gene3D G3DSA:3.90.1210.10 282 350 7.1E-24 T 12-10-2018 HW35_01745 4348f228c8cc0face8e723144c419105 230 SMART SM00448 3 113 1.7E-40 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_01745 4348f228c8cc0face8e723144c419105 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 8.0E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_01745 4348f228c8cc0face8e723144c419105 230 Gene3D G3DSA:3.40.50.2300 1 122 4.8E-36 T 12-10-2018 HW35_01745 4348f228c8cc0face8e723144c419105 230 Gene3D G3DSA:1.10.10.10 124 230 1.2E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_01745 4348f228c8cc0face8e723144c419105 230 SMART SM00862 152 229 9.9E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_01745 4348f228c8cc0face8e723144c419105 230 Pfam PF00072 Response regulator receiver domain 5 114 1.5E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_01745 4348f228c8cc0face8e723144c419105 230 SUPERFAMILY SSF46894 128 229 9.35E-29 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_01745 4348f228c8cc0face8e723144c419105 230 SUPERFAMILY SSF52172 4 119 1.71E-39 T 12-10-2018 IPR011006 CheY-like superfamily HW35_13295 8850c009ee6a4d27d89d29f7a10a83ab 342 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 7.1E-79 T 12-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HW35_13295 8850c009ee6a4d27d89d29f7a10a83ab 342 SUPERFAMILY SSF48179 183 329 2.55E-70 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_13295 8850c009ee6a4d27d89d29f7a10a83ab 342 PIRSF PIRSF000116 202 332 5.0E-17 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HW35_13295 8850c009ee6a4d27d89d29f7a10a83ab 342 PIRSF PIRSF000116 3 206 1.0E-42 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HW35_13295 8850c009ee6a4d27d89d29f7a10a83ab 342 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 2.5E-66 T 12-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HW35_13295 8850c009ee6a4d27d89d29f7a10a83ab 342 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 3.7E-147 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HW35_13295 8850c009ee6a4d27d89d29f7a10a83ab 342 SUPERFAMILY SSF51735 3 182 1.9E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_13295 8850c009ee6a4d27d89d29f7a10a83ab 342 Gene3D G3DSA:3.40.50.720 1 181 1.0E-78 T 12-10-2018 HW35_13295 8850c009ee6a4d27d89d29f7a10a83ab 342 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 45.897 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HW35_13295 8850c009ee6a4d27d89d29f7a10a83ab 342 Gene3D G3DSA:1.10.3730.40 182 336 3.5E-70 T 12-10-2018 HW35_01780 7b9df215878a7554c059412cf206254a 277 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 3.3E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_01780 7b9df215878a7554c059412cf206254a 277 Gene3D G3DSA:1.10.357.10 1 178 4.3E-28 T 12-10-2018 HW35_01780 7b9df215878a7554c059412cf206254a 277 SUPERFAMILY SSF46689 3 66 2.72E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_01780 7b9df215878a7554c059412cf206254a 277 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 7.0E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_01780 7b9df215878a7554c059412cf206254a 277 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 7.0E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 Pfam PF00535 Glycosyl transferase family 2 5 114 9.0E-19 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 SUPERFAMILY SSF48452 196 348 2.02E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 SMART SM00028 233 266 41.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 SMART SM00028 267 300 0.02 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 SMART SM00028 312 345 29.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 SMART SM00028 195 228 220.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 Gene3D G3DSA:3.90.550.10 2 169 1.2E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 Gene3D G3DSA:1.25.40.10 266 366 9.7E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 SUPERFAMILY SSF53448 3 157 8.06E-28 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 Pfam PF13181 Tetratricopeptide repeat 269 300 0.0099 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 Pfam PF13181 Tetratricopeptide repeat 234 262 0.019 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 Pfam PF13181 Tetratricopeptide repeat 205 223 0.18 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_02275 88b42ada24afe05314bc344fffb60e5f 366 Gene3D G3DSA:1.25.40.10 177 264 1.5E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_14870 84255b4582f4be33db339e859c11f8a5 299 Pfam PF13732 Domain of unknown function (DUF4162) 212 294 9.0E-20 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 HW35_14870 84255b4582f4be33db339e859c11f8a5 299 SMART SM00382 27 240 1.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_14870 84255b4582f4be33db339e859c11f8a5 299 Gene3D G3DSA:3.40.50.300 1 230 2.6E-61 T 12-10-2018 HW35_14870 84255b4582f4be33db339e859c11f8a5 299 SUPERFAMILY SSF52540 2 221 1.13E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14870 84255b4582f4be33db339e859c11f8a5 299 Pfam PF00005 ABC transporter 18 158 6.6E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_14870 84255b4582f4be33db339e859c11f8a5 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_05010 86ebd837ed3251b17b883e0e7f7df456 382 SUPERFAMILY SSF53383 1 374 2.26E-86 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_05010 86ebd837ed3251b17b883e0e7f7df456 382 Gene3D G3DSA:3.40.640.10 13 254 1.6E-112 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_05010 86ebd837ed3251b17b883e0e7f7df456 382 PIRSF PIRSF005572 1 378 1.1E-107 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 HW35_05010 86ebd837ed3251b17b883e0e7f7df456 382 Pfam PF00266 Aminotransferase class-V 2 365 8.9E-66 T 12-10-2018 IPR000192 Aminotransferase class V domain HW35_05010 86ebd837ed3251b17b883e0e7f7df456 382 Gene3D G3DSA:3.90.1150.10 2 372 1.6E-112 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_10800 83ded102bd2bbeb894d84d270cc885e8 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 4.9E-73 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 HW35_10800 83ded102bd2bbeb894d84d270cc885e8 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 1.1E-30 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 HW35_10800 83ded102bd2bbeb894d84d270cc885e8 166 SUPERFAMILY SSF54211 80 159 4.55E-26 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_10800 83ded102bd2bbeb894d84d270cc885e8 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 8.4E-34 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 HW35_10800 83ded102bd2bbeb894d84d270cc885e8 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site HW35_10800 83ded102bd2bbeb894d84d270cc885e8 166 Gene3D G3DSA:3.30.160.20 1 73 1.6E-36 T 12-10-2018 HW35_10800 83ded102bd2bbeb894d84d270cc885e8 166 Gene3D G3DSA:3.30.230.10 74 166 4.2E-37 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_10800 83ded102bd2bbeb894d84d270cc885e8 166 SUPERFAMILY SSF54768 8 76 1.05E-25 T 12-10-2018 HW35_10800 83ded102bd2bbeb894d84d270cc885e8 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 37.595 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 HW35_01815 4a40329e1e8a03fd6b39ae010e106a6b 284 Pfam PF01048 Phosphorylase superfamily 33 238 1.3E-36 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HW35_01815 4a40329e1e8a03fd6b39ae010e106a6b 284 SUPERFAMILY SSF53167 21 243 2.75E-65 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 HW35_01815 4a40329e1e8a03fd6b39ae010e106a6b 284 Gene3D G3DSA:3.40.50.1580 11 264 1.0E-73 T 12-10-2018 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 Gene3D G3DSA:2.40.240.10 344 462 2.5E-82 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 Gene3D G3DSA:3.90.800.10 97 205 1.1E-100 T 12-10-2018 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 SUPERFAMILY SSF50715 336 547 9.42E-76 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 Gene3D G3DSA:1.10.1160.10 257 335 3.4E-34 T 12-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 Gene3D G3DSA:3.40.50.620 25 243 1.1E-100 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 549 51.384 T 12-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 26 549 5.8E-229 T 12-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 SUPERFAMILY SSF52374 8 332 2.82E-97 T 12-10-2018 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 PRINTS PR00987 Glutamyl-tRNA synthetase signature 57 70 2.3E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 PRINTS PR00987 Glutamyl-tRNA synthetase signature 42 53 2.3E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 PRINTS PR00987 Glutamyl-tRNA synthetase signature 206 216 2.3E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 PRINTS PR00987 Glutamyl-tRNA synthetase signature 28 40 2.3E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 Gene3D G3DSA:2.40.240.10 336 546 2.5E-82 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 24 333 5.4E-108 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 336 528 9.6E-60 T 12-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HW35_13530 7d8e88031ffe34984832eb9cd3d41fb7 551 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 31 42 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 Gene3D G3DSA:1.10.150.20 66 140 3.4E-25 T 12-10-2018 HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 Pfam PF01330 RuvA N terminal domain 3 61 8.5E-19 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 3 202 8.0E-61 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 SMART SM00278 72 91 0.39 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 SMART SM00278 107 126 3.7 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 SUPERFAMILY SSF47781 64 136 6.67E-21 T 12-10-2018 IPR010994 RuvA domain 2-like HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 Pfam PF07499 RuvA, C-terminal domain 158 201 4.0E-12 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 SUPERFAMILY SSF46929 156 201 1.2E-10 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 Pfam PF14520 Helix-hairpin-helix domain 71 128 2.6E-14 T 12-10-2018 HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 SUPERFAMILY SSF50249 2 62 8.57E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 Gene3D G3DSA:1.10.8.10 153 201 1.9E-7 T 12-10-2018 HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 Gene3D G3DSA:2.40.50.140 1 64 5.0E-18 T 12-10-2018 HW35_04970 730426651053133c3b0eea3bc6aa89d2 203 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 202 29.556 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 SUPERFAMILY SSF46689 356 466 2.47E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 Gene3D G3DSA:3.30.450.20 1 121 1.8E-13 T 12-10-2018 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 Pfam PF02954 Bacterial regulatory protein, Fis family 424 464 1.9E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 Gene3D G3DSA:3.40.50.300 130 313 1.5E-61 T 12-10-2018 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 Gene3D G3DSA:1.10.10.60 417 468 1.4E-15 T 12-10-2018 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 Pfam PF00158 Sigma-54 interaction domain 144 309 1.9E-63 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 SMART SM00382 164 306 2.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_01110 9036b7c361e352000b8419aded4a0cac 468 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 Pfam PF13426 PAS domain 24 122 1.6E-6 T 12-10-2018 IPR000014 PAS domain HW35_01110 9036b7c361e352000b8419aded4a0cac 468 Gene3D G3DSA:1.10.8.60 314 381 2.6E-23 T 12-10-2018 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 SUPERFAMILY SSF52540 144 386 4.26E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_01110 9036b7c361e352000b8419aded4a0cac 468 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 447 467 6.8E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 430 447 6.8E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HW35_01110 9036b7c361e352000b8419aded4a0cac 468 SUPERFAMILY SSF55785 4 118 6.98E-9 T 12-10-2018 IPR035965 PAS domain superfamily HW35_01110 9036b7c361e352000b8419aded4a0cac 468 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 125 2.0E-6 T 12-10-2018 IPR000014 PAS domain HW35_09605 487fe7d64e6173cf0675ccbc4a4daabf 388 Gene3D G3DSA:3.30.420.40 8 201 3.6E-29 T 12-10-2018 HW35_09605 487fe7d64e6173cf0675ccbc4a4daabf 388 SUPERFAMILY SSF53067 204 338 4.1E-16 T 12-10-2018 HW35_09605 487fe7d64e6173cf0675ccbc4a4daabf 388 SUPERFAMILY SSF53067 6 195 1.12E-8 T 12-10-2018 HW35_09605 487fe7d64e6173cf0675ccbc4a4daabf 388 Gene3D G3DSA:3.30.420.40 202 337 3.6E-29 T 12-10-2018 HW35_09605 487fe7d64e6173cf0675ccbc4a4daabf 388 Pfam PF06406 StbA protein 173 338 1.4E-7 T 12-10-2018 IPR009440 Plasmid segregation protein ParM/StbA HW35_10880 1e0a97d3d393f0dd7553ae77d580c9be 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 HW35_10880 1e0a97d3d393f0dd7553ae77d580c9be 130 Gene3D G3DSA:3.30.230.10 4 130 3.9E-53 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_10880 1e0a97d3d393f0dd7553ae77d580c9be 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 2.8E-47 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 HW35_10880 1e0a97d3d393f0dd7553ae77d580c9be 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.942 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid HW35_10880 1e0a97d3d393f0dd7553ae77d580c9be 130 SUPERFAMILY SSF54211 5 130 9.48E-51 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_07710 1eb270990c411bb2483a21333c525b72 957 SMART SM00382 25 564 13.0 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_07710 1eb270990c411bb2483a21333c525b72 957 SMART SM00382 631 953 6.1E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_07710 1eb270990c411bb2483a21333c525b72 957 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 23.771 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 HW35_07710 1eb270990c411bb2483a21333c525b72 957 Gene3D G3DSA:1.10.8.280 286 403 3.2E-256 T 12-10-2018 HW35_07710 1eb270990c411bb2483a21333c525b72 957 Pfam PF00005 ABC transporter 622 858 1.0E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_07710 1eb270990c411bb2483a21333c525b72 957 Gene3D G3DSA:3.30.190.20 132 241 3.2E-256 T 12-10-2018 HW35_07710 1eb270990c411bb2483a21333c525b72 957 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 923 0.0 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 HW35_07710 1eb270990c411bb2483a21333c525b72 957 SUPERFAMILY SSF52540 614 912 1.06E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07710 1eb270990c411bb2483a21333c525b72 957 Gene3D G3DSA:1.20.1580.10 691 828 4.9E-146 T 12-10-2018 HW35_07710 1eb270990c411bb2483a21333c525b72 957 Gene3D G3DSA:3.40.50.300 7 595 3.2E-256 T 12-10-2018 HW35_07710 1eb270990c411bb2483a21333c525b72 957 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_07710 1eb270990c411bb2483a21333c525b72 957 Gene3D G3DSA:3.40.50.300 612 934 4.9E-146 T 12-10-2018 HW35_07710 1eb270990c411bb2483a21333c525b72 957 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_07710 1eb270990c411bb2483a21333c525b72 957 Gene3D G3DSA:1.20.1580.10 92 492 3.2E-256 T 12-10-2018 HW35_07710 1eb270990c411bb2483a21333c525b72 957 SUPERFAMILY SSF52540 12 569 3.82E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 Hamap MF_01987 Ribokinase [rbsK]. 2 291 24.749 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 236 249 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 Gene3D G3DSA:3.40.1190.20 1 290 2.1E-95 T 12-10-2018 IPR029056 Ribokinase-like HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 PRINTS PR00990 Ribokinase signature 6 27 6.3E-34 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 PRINTS PR00990 Ribokinase signature 33 52 6.3E-34 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 PRINTS PR00990 Ribokinase signature 172 187 6.3E-34 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 PRINTS PR00990 Ribokinase signature 104 117 6.3E-34 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 PRINTS PR00990 Ribokinase signature 207 218 6.3E-34 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 289 1.1E-108 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 SUPERFAMILY SSF53613 3 290 3.74E-82 T 12-10-2018 IPR029056 Ribokinase-like HW35_04860 d4f475f540ad923c3f3ad5c7b2d764f8 292 Pfam PF00294 pfkB family carbohydrate kinase 1 284 2.8E-76 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB HW35_05785 22c600012d78a309aed279733bc91d50 170 Pfam PF00994 Probable molybdopterin binding domain 18 161 2.4E-34 T 12-10-2018 IPR001453 MoaB/Mog domain HW35_05785 22c600012d78a309aed279733bc91d50 170 SUPERFAMILY SSF53218 8 167 1.7E-42 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily HW35_05785 22c600012d78a309aed279733bc91d50 170 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 HW35_05785 22c600012d78a309aed279733bc91d50 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 15 157 6.7E-36 T 12-10-2018 IPR001453 MoaB/Mog domain HW35_05785 22c600012d78a309aed279733bc91d50 170 SMART SM00852 17 162 2.0E-27 T 12-10-2018 IPR001453 MoaB/Mog domain HW35_05785 22c600012d78a309aed279733bc91d50 170 Gene3D G3DSA:3.40.980.10 1 169 9.9E-50 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily HW35_05785 22c600012d78a309aed279733bc91d50 170 PIRSF PIRSF006443 1 170 4.8E-67 T 12-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 HW35_05015 df7b1d36705d9279ba6f58c91d2b424a 179 SUPERFAMILY SSF75500 77 178 1.96E-35 T 12-10-2018 IPR035922 3H domain superfamily HW35_05015 df7b1d36705d9279ba6f58c91d2b424a 179 SUPERFAMILY SSF46785 8 67 1.13E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_05015 df7b1d36705d9279ba6f58c91d2b424a 179 Pfam PF08279 HTH domain 12 64 8.8E-14 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 HW35_05015 df7b1d36705d9279ba6f58c91d2b424a 179 PIRSF PIRSF037847 7 179 5.1E-67 T 12-10-2018 IPR026043 Transcription repressor NadR HW35_05015 df7b1d36705d9279ba6f58c91d2b424a 179 Gene3D G3DSA:3.30.1340.20 74 179 3.6E-37 T 12-10-2018 IPR035922 3H domain superfamily HW35_05015 df7b1d36705d9279ba6f58c91d2b424a 179 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 83 177 7.0E-29 T 12-10-2018 IPR004173 3H domain GO:0036094 HW35_05015 df7b1d36705d9279ba6f58c91d2b424a 179 Pfam PF02829 3H domain 80 176 1.4E-35 T 12-10-2018 IPR004173 3H domain GO:0036094 HW35_05015 df7b1d36705d9279ba6f58c91d2b424a 179 Gene3D G3DSA:1.10.10.10 1 67 1.8E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_12060 0817b200907b6316326d244da85e8848 394 Pfam PF00288 GHMP kinases N terminal domain 116 181 4.6E-12 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 HW35_12060 0817b200907b6316326d244da85e8848 394 Hamap MF_00246 Galactokinase [galK]. 24 386 48.794 T 12-10-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12060 0817b200907b6316326d244da85e8848 394 PRINTS PR00959 Mevalonate kinase family signature 119 141 1.6E-43 T 12-10-2018 HW35_12060 0817b200907b6316326d244da85e8848 394 PRINTS PR00959 Mevalonate kinase family signature 333 350 1.6E-43 T 12-10-2018 HW35_12060 0817b200907b6316326d244da85e8848 394 PRINTS PR00959 Mevalonate kinase family signature 162 181 1.6E-43 T 12-10-2018 HW35_12060 0817b200907b6316326d244da85e8848 394 PRINTS PR00959 Mevalonate kinase family signature 24 48 1.6E-43 T 12-10-2018 HW35_12060 0817b200907b6316326d244da85e8848 394 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 HW35_12060 0817b200907b6316326d244da85e8848 394 SUPERFAMILY SSF54211 5 203 8.35E-62 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_12060 0817b200907b6316326d244da85e8848 394 PRINTS PR00473 Galactokinase signature 91 102 5.3E-28 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12060 0817b200907b6316326d244da85e8848 394 PRINTS PR00473 Galactokinase signature 269 283 5.3E-28 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12060 0817b200907b6316326d244da85e8848 394 PRINTS PR00473 Galactokinase signature 26 44 5.3E-28 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12060 0817b200907b6316326d244da85e8848 394 PRINTS PR00473 Galactokinase signature 112 130 5.3E-28 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12060 0817b200907b6316326d244da85e8848 394 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 12-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12060 0817b200907b6316326d244da85e8848 394 TIGRFAM TIGR00131 gal_kin: galactokinase 6 387 8.5E-127 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12060 0817b200907b6316326d244da85e8848 394 Pfam PF08544 GHMP kinases C terminal 284 365 2.1E-13 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain HW35_12060 0817b200907b6316326d244da85e8848 394 Gene3D G3DSA:3.30.230.10 21 201 5.6E-141 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_12060 0817b200907b6316326d244da85e8848 394 SUPERFAMILY SSF55060 207 385 3.5E-56 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily HW35_12060 0817b200907b6316326d244da85e8848 394 Pfam PF10509 Galactokinase galactose-binding signature 9 57 1.6E-20 T 12-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12060 0817b200907b6316326d244da85e8848 394 Gene3D G3DSA:3.30.70.890 202 361 5.6E-141 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily HW35_12060 0817b200907b6316326d244da85e8848 394 PIRSF PIRSF000530 1 389 1.1E-122 T 12-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_04135 a4c2700f5a416c2181d95539deaa176d 278 SUPERFAMILY SSF55681 5 278 1.57E-74 T 12-10-2018 HW35_04135 a4c2700f5a416c2181d95539deaa176d 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 189 5.8E-28 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 HW35_04135 a4c2700f5a416c2181d95539deaa176d 278 Gene3D G3DSA:3.30.930.10 6 278 6.5E-72 T 12-10-2018 HW35_04135 a4c2700f5a416c2181d95539deaa176d 278 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 3 278 67.886 T 12-10-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 HW35_03700 de20af95703d167d19ec88f4a65987fd 395 Pfam PF01676 Metalloenzyme superfamily 7 380 1.9E-45 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 HW35_03700 de20af95703d167d19ec88f4a65987fd 395 Hamap MF_00740 Phosphopentomutase [deoB]. 6 390 56.717 T 12-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 HW35_03700 de20af95703d167d19ec88f4a65987fd 395 PIRSF PIRSF001491 5 394 1.1E-171 T 12-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 HW35_03700 de20af95703d167d19ec88f4a65987fd 395 Gene3D G3DSA:3.30.70.1250 101 219 7.9E-180 T 12-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 HW35_03700 de20af95703d167d19ec88f4a65987fd 395 SUPERFAMILY SSF143856 103 219 3.27E-53 T 12-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 HW35_03700 de20af95703d167d19ec88f4a65987fd 395 SUPERFAMILY SSF53649 5 393 5.12E-80 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 HW35_03700 de20af95703d167d19ec88f4a65987fd 395 TIGRFAM TIGR01696 deoB: phosphopentomutase 8 388 8.3E-211 T 12-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 HW35_03700 de20af95703d167d19ec88f4a65987fd 395 Gene3D G3DSA:3.40.720.10 7 390 7.9E-180 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 HW35_08070 8f9cb93a08e3414e2afa775250e80c86 350 SUPERFAMILY SSF49503 192 343 8.15E-37 T 12-10-2018 IPR008972 Cupredoxin HW35_08070 8f9cb93a08e3414e2afa775250e80c86 350 Pfam PF07732 Multicopper oxidase 78 185 1.3E-11 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 HW35_08070 8f9cb93a08e3414e2afa775250e80c86 350 Pfam PF07731 Multicopper oxidase 236 338 1.6E-4 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 HW35_08070 8f9cb93a08e3414e2afa775250e80c86 350 PRINTS PR00695 Copper containing nitrite reductase signature 91 107 1.6E-13 T 12-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 HW35_08070 8f9cb93a08e3414e2afa775250e80c86 350 PRINTS PR00695 Copper containing nitrite reductase signature 149 164 1.6E-13 T 12-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 HW35_08070 8f9cb93a08e3414e2afa775250e80c86 350 PRINTS PR00695 Copper containing nitrite reductase signature 166 182 1.6E-13 T 12-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 HW35_08070 8f9cb93a08e3414e2afa775250e80c86 350 Gene3D G3DSA:2.60.40.420 46 350 3.7E-83 T 12-10-2018 IPR008972 Cupredoxin HW35_08070 8f9cb93a08e3414e2afa775250e80c86 350 SUPERFAMILY SSF49503 60 204 2.57E-33 T 12-10-2018 IPR008972 Cupredoxin HW35_06415 ffc2e479e473bd5275190806865322c7 483 SUPERFAMILY SSF53756 3 476 1.47E-129 T 12-10-2018 HW35_06415 ffc2e479e473bd5275190806865322c7 483 Hamap MF_00484 Glycogen synthase [glgA]. 1 474 46.662 T 12-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 HW35_06415 ffc2e479e473bd5275190806865322c7 483 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 2 473 2.9E-174 T 12-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 HW35_06415 ffc2e479e473bd5275190806865322c7 483 Pfam PF08323 Starch synthase catalytic domain 2 236 3.0E-89 T 12-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 HW35_06415 ffc2e479e473bd5275190806865322c7 483 Pfam PF00534 Glycosyl transferases group 1 289 438 7.8E-18 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 HW35_06415 ffc2e479e473bd5275190806865322c7 483 Gene3D G3DSA:3.40.50.2000 3 472 6.0E-187 T 12-10-2018 HW35_06415 ffc2e479e473bd5275190806865322c7 483 Gene3D G3DSA:3.40.50.2000 250 458 6.0E-187 T 12-10-2018 HW35_17240 fc0321cee78dd0b70c25e39417c394fd 592 SUPERFAMILY SSF90123 18 335 3.92E-73 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_17240 fc0321cee78dd0b70c25e39417c394fd 592 SUPERFAMILY SSF52540 344 584 1.81E-88 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17240 fc0321cee78dd0b70c25e39417c394fd 592 Pfam PF00664 ABC transporter transmembrane region 31 303 5.8E-42 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 HW35_17240 fc0321cee78dd0b70c25e39417c394fd 592 SMART SM00382 374 566 2.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_17240 fc0321cee78dd0b70c25e39417c394fd 592 Gene3D G3DSA:1.20.1560.10 2 334 2.9E-82 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_17240 fc0321cee78dd0b70c25e39417c394fd 592 Pfam PF00005 ABC transporter 365 514 2.9E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_17240 fc0321cee78dd0b70c25e39417c394fd 592 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_17240 fc0321cee78dd0b70c25e39417c394fd 592 Gene3D G3DSA:3.40.50.300 345 591 1.7E-90 T 12-10-2018 HW35_11825 eafc12fdd58170cd7c1592b8725f75c2 483 ProSitePatterns PS00571 Amidases signature. 150 181 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 HW35_11825 eafc12fdd58170cd7c1592b8725f75c2 483 SUPERFAMILY SSF75304 3 481 1.83E-168 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HW35_11825 eafc12fdd58170cd7c1592b8725f75c2 483 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 475 97.218 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HW35_11825 eafc12fdd58170cd7c1592b8725f75c2 483 Pfam PF01425 Amidase 24 463 1.0E-163 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HW35_11825 eafc12fdd58170cd7c1592b8725f75c2 483 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 475 2.1E-207 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HW35_11825 eafc12fdd58170cd7c1592b8725f75c2 483 Gene3D G3DSA:3.90.1300.10 2 483 1.1E-201 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 448 9.3E-81 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 Gene3D G3DSA:1.20.120.1320 39 135 5.4E-74 T 12-10-2018 HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 SUPERFAMILY SSF53633 1 290 1.96E-66 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 Pfam PF13840 ACT domain 380 445 1.4E-7 T 12-10-2018 IPR027795 CASTOR, ACT domain HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 SUPERFAMILY SSF55021 373 449 1.05E-20 T 12-10-2018 HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 Pfam PF00696 Amino acid kinase family 2 276 6.7E-39 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 PIRSF PIRSF000726 1 451 5.7E-78 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 SUPERFAMILY SSF55021 296 361 1.17E-7 T 12-10-2018 HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 Gene3D G3DSA:3.40.1160.10 3 287 5.4E-74 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_02360 e4960afcf9323373ca7f76ef01d1b6cc 453 Gene3D G3DSA:3.30.2130.10 290 450 6.4E-57 T 12-10-2018 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 Pfam PF01018 GTP1/OBG 3 157 1.4E-60 T 12-10-2018 IPR006169 GTP1/OBG domain HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 1.1E-13 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 Pfam PF09269 Domain of unknown function (DUF1967) 359 427 4.7E-26 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 Gene3D G3DSA:2.70.210.12 1 157 8.8E-61 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 PIRSF PIRSF002401 1 377 4.3E-144 T 12-10-2018 IPR035101 GTP-binding protein, Obg-type HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 2.4E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 2.4E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 2.4E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 2.4E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 5.0E-144 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 Pfam PF01926 50S ribosome-binding GTPase 160 283 1.1E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 SUPERFAMILY SSF52540 151 332 5.14E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 Gene3D G3DSA:3.40.50.300 158 341 7.2E-62 T 12-10-2018 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 Gene3D G3DSA:2.40.240.60 358 429 6.7E-17 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 359 427 5.1E-27 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 SUPERFAMILY SSF102741 357 429 3.53E-24 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 SUPERFAMILY SSF82051 1 157 3.92E-56 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily HW35_05030 959e9c31223de0dafcf3a6442b015d1b 429 Hamap MF_01454 GTPase Obg [obg]. 1 329 48.363 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HW35_12120 76a1c47094a877942dd5d01794e4fdb0 129 Gene3D G3DSA:1.10.10.10 9 126 4.5E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_12120 76a1c47094a877942dd5d01794e4fdb0 129 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 1.3E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_12120 76a1c47094a877942dd5d01794e4fdb0 129 SMART SM00345 16 75 9.4E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_12120 76a1c47094a877942dd5d01794e4fdb0 129 SUPERFAMILY SSF46785 5 79 2.82E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_09835 91d2afce64de2c075f3a892c078958f5 430 Gene3D G3DSA:1.10.300.10 100 199 2.6E-105 T 12-10-2018 HW35_09835 91d2afce64de2c075f3a892c078958f5 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HW35_09835 91d2afce64de2c075f3a892c078958f5 430 Pfam PF00709 Adenylosuccinate synthetase 4 420 4.4E-185 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HW35_09835 91d2afce64de2c075f3a892c078958f5 430 SMART SM00788 3 422 6.1E-292 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HW35_09835 91d2afce64de2c075f3a892c078958f5 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 426 8.9E-196 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HW35_09835 91d2afce64de2c075f3a892c078958f5 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 213.501 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HW35_09835 91d2afce64de2c075f3a892c078958f5 430 Gene3D G3DSA:3.90.170.10 265 429 1.2E-71 T 12-10-2018 HW35_09835 91d2afce64de2c075f3a892c078958f5 430 Gene3D G3DSA:3.40.440.10 5 252 2.6E-105 T 12-10-2018 HW35_09835 91d2afce64de2c075f3a892c078958f5 430 SUPERFAMILY SSF52540 1 427 1.7E-176 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09835 91d2afce64de2c075f3a892c078958f5 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HW35_04130 72e37aa4571abe374b1c6b58095d4249 267 SUPERFAMILY SSF51998 129 264 4.88E-37 T 12-10-2018 HW35_04130 72e37aa4571abe374b1c6b58095d4249 267 Pfam PF02867 Ribonucleotide reductase, barrel domain 187 265 5.0E-14 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_04130 72e37aa4571abe374b1c6b58095d4249 267 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 130 180 2.7E-9 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_04130 72e37aa4571abe374b1c6b58095d4249 267 Gene3D G3DSA:3.20.70.20 123 267 1.2E-34 T 12-10-2018 HW35_10650 4520879afd81d0949d9928cae2d01f49 141 SUPERFAMILY SSF54747 2 84 1.03E-30 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily HW35_10650 4520879afd81d0949d9928cae2d01f49 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 2.5E-31 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal HW35_10650 4520879afd81d0949d9928cae2d01f49 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 9.7E-66 T 12-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10650 4520879afd81d0949d9928cae2d01f49 141 SMART SM00649 9 140 3.1E-88 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HW35_10650 4520879afd81d0949d9928cae2d01f49 141 Gene3D G3DSA:1.10.10.250 72 140 3.4E-29 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily HW35_10650 4520879afd81d0949d9928cae2d01f49 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 4.5E-26 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HW35_10650 4520879afd81d0949d9928cae2d01f49 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 12-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10650 4520879afd81d0949d9928cae2d01f49 141 SUPERFAMILY SSF46906 67 140 2.22E-27 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily HW35_10650 4520879afd81d0949d9928cae2d01f49 141 Gene3D G3DSA:3.30.1550.10 2 71 2.2E-34 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily HW35_10650 4520879afd81d0949d9928cae2d01f49 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 3.0E-16 T 12-10-2018 HW35_10650 4520879afd81d0949d9928cae2d01f49 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.883 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HW35_16935 d9463f66bedbe2318413bb5cbf583306 509 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_16935 d9463f66bedbe2318413bb5cbf583306 509 Gene3D G3DSA:3.40.50.300 1 236 2.0E-56 T 12-10-2018 HW35_16935 d9463f66bedbe2318413bb5cbf583306 509 Gene3D G3DSA:3.40.50.300 251 494 1.4E-42 T 12-10-2018 HW35_16935 d9463f66bedbe2318413bb5cbf583306 509 SMART SM00382 29 217 5.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_16935 d9463f66bedbe2318413bb5cbf583306 509 Pfam PF00005 ABC transporter 21 169 2.0E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_16935 d9463f66bedbe2318413bb5cbf583306 509 Pfam PF00005 ABC transporter 274 429 1.5E-15 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_16935 d9463f66bedbe2318413bb5cbf583306 509 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_16935 d9463f66bedbe2318413bb5cbf583306 509 SUPERFAMILY SSF52540 256 488 1.48E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16935 d9463f66bedbe2318413bb5cbf583306 509 SUPERFAMILY SSF52540 3 227 7.74E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_06105 3c619b1162e28fcda2907e23d399a26b 61 ProDom PD052690 CSE60 CYTOSOLIC YTEV LJ928 SPORULATION ORF85 PROPHAGE 1 60 1.0E-13 T 12-10-2018 IPR020296 Sporulation protein Cse60 HW35_06105 3c619b1162e28fcda2907e23d399a26b 61 Pfam PF10957 Sporulation protein Cse60 1 61 9.0E-31 T 12-10-2018 IPR020296 Sporulation protein Cse60 HW35_00250 3db4a462c917f670fe739655570d11ea 141 SUPERFAMILY SSF50341 2 138 4.05E-36 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 HW35_00250 3db4a462c917f670fe739655570d11ea 141 Pfam PF01584 CheW-like domain 6 137 2.3E-34 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HW35_00250 3db4a462c917f670fe739655570d11ea 141 SMART SM00260 1 136 5.4E-30 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HW35_00250 3db4a462c917f670fe739655570d11ea 141 Gene3D G3DSA:2.30.30.40 7 130 6.7E-39 T 12-10-2018 HW35_00250 3db4a462c917f670fe739655570d11ea 141 Gene3D G3DSA:2.40.50.180 22 135 6.7E-39 T 12-10-2018 HW35_17700 9b4f6314e45fa4b6935b5e3a1f2a6e15 417 SUPERFAMILY SSF55031 197 290 1.05E-24 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain HW35_17700 9b4f6314e45fa4b6935b5e3a1f2a6e15 417 Pfam PF01546 Peptidase family M20/M25/M40 79 395 3.5E-35 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 HW35_17700 9b4f6314e45fa4b6935b5e3a1f2a6e15 417 Gene3D G3DSA:3.30.70.360 194 307 4.9E-127 T 12-10-2018 HW35_17700 9b4f6314e45fa4b6935b5e3a1f2a6e15 417 Pfam PF07687 Peptidase dimerisation domain 199 292 1.3E-8 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain HW35_17700 9b4f6314e45fa4b6935b5e3a1f2a6e15 417 PIRSF PIRSF005962 6 402 1.0E-113 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 HW35_17700 9b4f6314e45fa4b6935b5e3a1f2a6e15 417 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 386 7.9E-121 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 HW35_17700 9b4f6314e45fa4b6935b5e3a1f2a6e15 417 Gene3D G3DSA:3.40.630.10 20 383 4.9E-127 T 12-10-2018 HW35_17700 9b4f6314e45fa4b6935b5e3a1f2a6e15 417 SUPERFAMILY SSF53187 14 399 1.98E-84 T 12-10-2018 HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 SUPERFAMILY SSF51261 481 612 2.09E-53 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 SUPERFAMILY SSF55604 383 456 7.19E-21 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 Gene3D G3DSA:3.30.1360.60 379 458 2.1E-25 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 Pfam PF02378 Phosphotransferase system, EIIC 9 293 3.1E-78 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 486 605 7.3E-46 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 484 607 5.7E-52 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 351 443 5.3E-21 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 396 413 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 547 559 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 454 2.0E-189 T 12-10-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 Gene3D G3DSA:2.70.70.10 476 628 1.7E-59 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_14610 6f436f1d1d2a0256fca57492495926fd 628 Pfam PF00367 phosphotransferase system, EIIB 388 418 5.3E-14 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 Pfam PF03123 CAT RNA binding domain 2 53 6.4E-19 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 Gene3D G3DSA:1.20.58.1950 220 271 7.0E-10 T 12-10-2018 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 Gene3D G3DSA:2.30.24.10 1 55 1.1E-21 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 SMART SM01061 1 58 8.8E-22 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 SUPERFAMILY SSF63520 51 162 1.57E-32 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 Pfam PF00874 PRD domain 71 158 1.6E-26 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 Pfam PF00874 PRD domain 179 268 4.4E-22 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 Gene3D G3DSA:1.10.1790.10 60 163 2.9E-36 T 12-10-2018 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 SUPERFAMILY SSF50151 2 53 1.96E-16 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 SUPERFAMILY SSF63520 169 270 2.75E-25 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_11990 79d87d026bb6a48014ed9686651b746f 272 Gene3D G3DSA:1.20.890.100 164 218 2.9E-15 T 12-10-2018 HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 SMART SM00798 135 447 3.2E-202 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 SUPERFAMILY SSF53927 208 512 2.71E-127 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 Gene3D G3DSA:3.40.50.1380 1 198 3.8E-88 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 SUPERFAMILY SSF52335 3 194 3.4E-71 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 Gene3D G3DSA:3.40.140.20 205 360 9.7E-61 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 SMART SM00851 15 130 2.0E-54 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 Gene3D G3DSA:3.40.140.20 386 512 1.6E-55 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 Pfam PF02142 MGS-like domain 18 129 1.4E-28 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 PIRSF PIRSF000414 1 512 2.6E-215 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 512 44.764 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 Pfam PF01808 AICARFT/IMPCHase bienzyme 136 445 4.9E-121 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11730 58c686f0cd0aab250a23be6fcd6613fd 512 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 512 6.3E-233 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 SUPERFAMILY SSF53822 72 323 1.08E-48 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.2E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 Gene3D G3DSA:3.40.50.2300 156 290 3.0E-49 T 12-10-2018 HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 Gene3D G3DSA:3.40.50.2300 73 315 3.0E-49 T 12-10-2018 HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 Pfam PF13377 Periplasmic binding protein-like domain 164 329 1.0E-35 T 12-10-2018 HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.0E-7 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.0E-7 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 SMART SM00354 1 70 1.4E-17 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 Gene3D G3DSA:1.10.260.40 1 47 5.2E-20 T 12-10-2018 HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 SUPERFAMILY SSF47413 3 49 2.06E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_12080 2c0ed365abb84b687a1ddef965c9e021 330 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 SUPERFAMILY SSF52467 200 369 1.77E-62 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 SUPERFAMILY SSF52518 377 573 1.6E-70 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 437 456 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 Gene3D G3DSA:3.40.50.1220 203 367 1.0E-61 T 12-10-2018 HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 17 572 3.1E-259 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 Gene3D G3DSA:3.40.50.970 4 191 5.8E-70 T 12-10-2018 HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 17 181 2.9E-56 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 Gene3D G3DSA:3.40.50.970 372 575 8.0E-71 T 12-10-2018 HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 SUPERFAMILY SSF52518 12 187 2.15E-61 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 208 342 1.3E-46 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 HW35_13305 ea83a9e08f2234ffce1089d54129529c 575 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 400 548 8.2E-52 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HW35_01015 1ec06fb9a08c7b7531c4416bd09e9cae 199 SMART SM01207 9 189 1.0E-76 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HW35_01015 1ec06fb9a08c7b7531c4416bd09e9cae 199 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 198 1.1E-62 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HW35_01015 1ec06fb9a08c7b7531c4416bd09e9cae 199 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 6 197 20.095 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HW35_01015 1ec06fb9a08c7b7531c4416bd09e9cae 199 Pfam PF02660 Glycerol-3-phosphate acyltransferase 10 188 5.2E-50 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 772 852 5.5E-26 T 12-10-2018 IPR019489 Clp ATPase, C-terminal HW35_15225 f1b88d650755740a71847cbe31d27c44 864 SMART SM01086 772 861 3.8E-33 T 12-10-2018 IPR019489 Clp ATPase, C-terminal HW35_15225 f1b88d650755740a71847cbe31d27c44 864 SUPERFAMILY SSF81923 4 159 3.4E-36 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 Gene3D G3DSA:1.10.1780.10 1 152 4.5E-32 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 SUPERFAMILY SSF52540 161 549 1.56E-101 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15225 f1b88d650755740a71847cbe31d27c44 864 SUPERFAMILY SSF52540 550 853 2.46E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15225 f1b88d650755740a71847cbe31d27c44 864 Gene3D G3DSA:3.40.50.300 347 548 1.9E-70 T 12-10-2018 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 SMART SM00382 202 348 1.8E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_15225 f1b88d650755740a71847cbe31d27c44 864 SMART SM00382 601 837 2.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_15225 f1b88d650755740a71847cbe31d27c44 864 Gene3D G3DSA:3.40.50.300 153 346 7.4E-75 T 12-10-2018 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 298 310 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 340 1.8E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 149 7.7E-8 T 12-10-2018 IPR004176 Clp, N-terminal HW35_15225 f1b88d650755740a71847cbe31d27c44 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 3.2E-10 T 12-10-2018 IPR004176 Clp, N-terminal HW35_15225 f1b88d650755740a71847cbe31d27c44 864 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 765 7.2E-56 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 861 0.0 T 12-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 Gene3D G3DSA:3.40.50.300 554 770 9.3E-88 T 12-10-2018 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 4.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 4.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 4.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 4.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_15225 f1b88d650755740a71847cbe31d27c44 864 Gene3D G3DSA:1.10.8.60 772 863 1.1E-25 T 12-10-2018 HW35_04715 bc58e0dfd4f160ef9d7ac57d4e936dae 235 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 47.264 T 12-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_04715 bc58e0dfd4f160ef9d7ac57d4e936dae 235 SUPERFAMILY SSF53167 1 228 1.44E-75 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 HW35_04715 bc58e0dfd4f160ef9d7ac57d4e936dae 235 Gene3D G3DSA:3.40.50.1580 1 235 1.3E-73 T 12-10-2018 HW35_04715 bc58e0dfd4f160ef9d7ac57d4e936dae 235 Pfam PF01048 Phosphorylase superfamily 2 228 4.0E-57 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HW35_04715 bc58e0dfd4f160ef9d7ac57d4e936dae 235 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 228 8.7E-111 T 12-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_15325 7bd30a036836db222e4fdf1caefb47da 312 SUPERFAMILY SSF52540 7 253 2.47E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15325 7bd30a036836db222e4fdf1caefb47da 312 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 280 2.7E-8 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_15325 7bd30a036836db222e4fdf1caefb47da 312 Gene3D G3DSA:3.40.50.300 5 311 2.0E-90 T 12-10-2018 HW35_15325 7bd30a036836db222e4fdf1caefb47da 312 SMART SM00382 37 231 6.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_15325 7bd30a036836db222e4fdf1caefb47da 312 Pfam PF00005 ABC transporter 28 181 3.3E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_15325 7bd30a036836db222e4fdf1caefb47da 312 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_05400 a3d620e99da565e612ccfa029a5a2a0e 74 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 64 6.1E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_05400 a3d620e99da565e612ccfa029a5a2a0e 74 Gene3D G3DSA:1.10.10.10 1 74 5.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_05400 a3d620e99da565e612ccfa029a5a2a0e 74 SUPERFAMILY SSF46894 8 72 3.74E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_05400 a3d620e99da565e612ccfa029a5a2a0e 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 12 26 1.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_05400 a3d620e99da565e612ccfa029a5a2a0e 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 26 42 1.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_05400 a3d620e99da565e612ccfa029a5a2a0e 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 54 1.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_05400 a3d620e99da565e612ccfa029a5a2a0e 74 SMART SM00421 9 66 4.4E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_05400 a3d620e99da565e612ccfa029a5a2a0e 74 ProSitePatterns PS00622 LuxR-type HTH domain signature. 26 53 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_16835 8bc2d3059fcba87164fbc5ebd0c04036 93 Pfam PF04456 Protein of unknown function (DUF503) 3 89 3.7E-30 T 12-10-2018 IPR007546 Protein of unknown function DUF503 HW35_16835 8bc2d3059fcba87164fbc5ebd0c04036 93 SUPERFAMILY SSF103007 1 93 1.26E-30 T 12-10-2018 IPR036746 TT1725-like superfamily HW35_16835 8bc2d3059fcba87164fbc5ebd0c04036 93 Gene3D G3DSA:3.30.70.1120 1 93 1.3E-24 T 12-10-2018 IPR036746 TT1725-like superfamily HW35_04765 4dffa759f2de26a6028fea3de6cacfbe 138 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 138 27.574 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 HW35_04765 4dffa759f2de26a6028fea3de6cacfbe 138 Pfam PF03652 Holliday junction resolvase 1 136 6.7E-45 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 HW35_04765 4dffa759f2de26a6028fea3de6cacfbe 138 Gene3D G3DSA:3.30.420.140 1 138 2.9E-51 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 HW35_04765 4dffa759f2de26a6028fea3de6cacfbe 138 SUPERFAMILY SSF53098 1 137 6.37E-45 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_04765 4dffa759f2de26a6028fea3de6cacfbe 138 SMART SM00732 1 103 1.6E-39 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 HW35_04765 4dffa759f2de26a6028fea3de6cacfbe 138 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 3.7E-51 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 HW35_05165 e36b09b558f335ef47771111f4737624 110 SUPERFAMILY SSF54523 19 83 2.59E-13 T 12-10-2018 HW35_05165 e36b09b558f335ef47771111f4737624 110 Pfam PF07963 Prokaryotic N-terminal methylation motif 13 37 1.7E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_05165 e36b09b558f335ef47771111f4737624 110 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 16 36 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_05165 e36b09b558f335ef47771111f4737624 110 Gene3D G3DSA:3.30.700.10 19 97 3.7E-12 T 12-10-2018 HW35_05165 e36b09b558f335ef47771111f4737624 110 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 38 1.5E-8 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 SUPERFAMILY SSF52021 1 145 9.15E-58 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 356 49.314 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 353 5.2E-146 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 Pfam PF00117 Glutamine amidotransferase class-I 174 350 1.8E-47 T 12-10-2018 IPR017926 Glutamine amidotransferase HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 Gene3D G3DSA:3.50.30.20 1 145 4.7E-56 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 SUPERFAMILY SSF52317 149 354 7.77E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00097 Anthranilate synthase component II signature 241 252 2.6E-6 T 12-10-2018 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00097 Anthranilate synthase component II signature 327 340 2.6E-6 T 12-10-2018 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00097 Anthranilate synthase component II signature 214 223 2.6E-6 T 12-10-2018 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 3.9E-38 T 12-10-2018 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 211 225 3.9E-38 T 12-10-2018 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 3.9E-38 T 12-10-2018 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 172 186 3.9E-38 T 12-10-2018 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 3.9E-38 T 12-10-2018 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 SMART SM01097 1 131 6.4E-89 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 Gene3D G3DSA:3.40.50.880 146 356 6.2E-65 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 1.1E-51 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00096 Glutamine amidotransferase superfamily signature 214 223 1.6E-11 T 12-10-2018 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 1.6E-11 T 12-10-2018 HW35_16480 f3e70f536de2b379bcb1155aef52e2a1 363 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 1.6E-11 T 12-10-2018 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 SUPERFAMILY SSF55804 553 699 3.79E-39 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 558 699 3.2E-34 T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 SUPERFAMILY SSF52794 419 501 1.52E-10 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Gene3D G3DSA:1.10.10.10 1 68 4.0E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Gene3D G3DSA:1.10.10.10 74 155 7.9E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 SUPERFAMILY SSF63520 316 412 6.02E-21 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Pfam PF00874 PRD domain 209 295 9.3E-16 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Pfam PF00874 PRD domain 321 408 1.4E-18 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Gene3D G3DSA:1.10.1790.10 199 300 3.1E-14 T 12-10-2018 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Gene3D G3DSA:3.40.50.2300 420 505 5.9E-13 T 12-10-2018 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 604 620 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Pfam PF05043 Mga helix-turn-helix domain 103 164 1.3E-6 T 12-10-2018 IPR007737 Mga helix-turn-helix domain HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 SUPERFAMILY SSF63520 202 297 2.88E-19 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Gene3D G3DSA:3.40.930.10 552 703 6.7E-56 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Gene3D G3DSA:1.10.1790.10 313 410 4.8E-15 T 12-10-2018 HW35_08555 80fe2688b4d8ff2dd1e8f287891270a1 703 Pfam PF08279 HTH domain 19 48 2.0E-4 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 HW35_02245 e2400eab58b54e79e9935b61c427b678 774 Pfam PF13245 AAA domain 218 581 2.3E-7 T 12-10-2018 HW35_02245 e2400eab58b54e79e9935b61c427b678 774 Gene3D G3DSA:3.40.50.300 605 773 1.0E-52 T 12-10-2018 HW35_02245 e2400eab58b54e79e9935b61c427b678 774 Pfam PF13538 UvrD-like helicase C-terminal domain 706 750 1.1E-6 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain HW35_02245 e2400eab58b54e79e9935b61c427b678 774 Gene3D G3DSA:3.40.50.300 393 600 6.5E-9 T 12-10-2018 HW35_02245 e2400eab58b54e79e9935b61c427b678 774 Gene3D G3DSA:3.40.50.300 206 378 2.2E-8 T 12-10-2018 HW35_02245 e2400eab58b54e79e9935b61c427b678 774 SUPERFAMILY SSF52540 206 754 8.71E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10775 b444b52e24bf18a8524ffb21b7252eb0 179 Pfam PF00281 Ribosomal protein L5 24 80 3.1E-29 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10775 b444b52e24bf18a8524ffb21b7252eb0 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 12-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10775 b444b52e24bf18a8524ffb21b7252eb0 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 7.0E-42 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10775 b444b52e24bf18a8524ffb21b7252eb0 179 PIRSF PIRSF002161 1 179 1.6E-71 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10775 b444b52e24bf18a8524ffb21b7252eb0 179 Gene3D G3DSA:3.30.1440.10 1 179 7.4E-85 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10775 b444b52e24bf18a8524ffb21b7252eb0 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 46.006 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10775 b444b52e24bf18a8524ffb21b7252eb0 179 SUPERFAMILY SSF55282 3 178 4.47E-79 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_13175 79f7878732b6cb454941c7932dcd204c 556 SUPERFAMILY SSF51011 479 555 6.24E-18 T 12-10-2018 HW35_13175 79f7878732b6cb454941c7932dcd204c 556 Pfam PF00128 Alpha amylase, catalytic domain 28 376 2.2E-118 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_13175 79f7878732b6cb454941c7932dcd204c 556 SMART SM00642 13 418 7.9E-169 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_13175 79f7878732b6cb454941c7932dcd204c 556 PRINTS PR00110 Alpha-amylase signature 193 204 8.2E-6 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 HW35_13175 79f7878732b6cb454941c7932dcd204c 556 PRINTS PR00110 Alpha-amylase signature 92 103 8.2E-6 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 HW35_13175 79f7878732b6cb454941c7932dcd204c 556 PRINTS PR00110 Alpha-amylase signature 319 331 8.2E-6 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 HW35_13175 79f7878732b6cb454941c7932dcd204c 556 Gene3D G3DSA:3.20.20.80 5 471 3.5E-200 T 12-10-2018 HW35_13175 79f7878732b6cb454941c7932dcd204c 556 Pfam PF16657 Maltogenic Amylase, C-terminal domain 479 551 8.1E-8 T 12-10-2018 IPR032091 Maltogenic Amylase, C-terminal HW35_13175 79f7878732b6cb454941c7932dcd204c 556 SUPERFAMILY SSF51445 4 476 2.5E-160 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_13175 79f7878732b6cb454941c7932dcd204c 556 Gene3D G3DSA:2.60.40.1180 480 556 4.4E-21 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta HW35_13175 79f7878732b6cb454941c7932dcd204c 556 Gene3D G3DSA:3.90.400.10 102 173 3.5E-200 T 12-10-2018 HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 Gene3D G3DSA:3.30.465.10 354 435 2.5E-22 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 Pfam PF03471 Transporter associated domain 356 434 3.8E-23 T 12-10-2018 IPR005170 Transporter-associated domain HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 SMART SM00116 225 274 2.8 T 12-10-2018 IPR000644 CBS domain HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 SMART SM00116 289 337 5.2 T 12-10-2018 IPR000644 CBS domain HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 Gene3D G3DSA:3.10.580.10 195 348 1.3E-56 T 12-10-2018 HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 SUPERFAMILY SSF56176 354 437 2.54E-21 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 SUPERFAMILY SSF54631 203 340 4.76E-34 T 12-10-2018 HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 Pfam PF00571 CBS domain 286 337 5.9E-5 T 12-10-2018 IPR000644 CBS domain HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 Pfam PF00571 CBS domain 216 274 3.0E-8 T 12-10-2018 IPR000644 CBS domain HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 SMART SM01091 355 435 3.7E-24 T 12-10-2018 IPR005170 Transporter-associated domain HW35_11970 89d1dfe942ed8df1596431cba0a17f64 444 Pfam PF01595 Domain of unknown function DUF21 7 201 6.7E-50 T 12-10-2018 IPR002550 CNNM, transmembrane domain HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 4 933 4.8E-268 T 12-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 Pfam PF00929 Exonuclease 6 162 6.0E-30 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 Gene3D G3DSA:3.40.50.300 724 927 8.3E-41 T 12-10-2018 HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 SUPERFAMILY SSF52540 275 895 3.47E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 SMART SM00487 255 524 0.0017 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 SUPERFAMILY SSF53098 4 201 1.28E-53 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 SMART SM00479 4 171 1.2E-45 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 Pfam PF13307 Helicase C-terminal domain 750 914 1.0E-37 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 171 1.2E-29 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 Pfam PF04851 Type III restriction enzyme, res subunit 258 469 3.7E-5 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 Gene3D G3DSA:3.30.420.10 1 171 5.3E-47 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 Hamap MF_02206 3'-5' exonuclease DinG [dinG]. 1 933 27.906 T 12-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 Gene3D G3DSA:3.40.50.300 257 511 1.8E-43 T 12-10-2018 HW35_03205 ca24aa699cbea4fb85d1130dd57f5e7d 933 SMART SM00491 767 901 3.0E-38 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 HW35_16785 60423cc2200f1c9003e421e4a6f80186 258 SUPERFAMILY SSF64005 28 252 8.5E-88 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 HW35_16785 60423cc2200f1c9003e421e4a6f80186 258 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 29 257 40.588 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HW35_16785 60423cc2200f1c9003e421e4a6f80186 258 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 29 256 4.0E-86 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HW35_16785 60423cc2200f1c9003e421e4a6f80186 258 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 202 219 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 HW35_16785 60423cc2200f1c9003e421e4a6f80186 258 Gene3D G3DSA:3.40.1180.10 12 258 1.6E-99 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 HW35_16785 60423cc2200f1c9003e421e4a6f80186 258 Pfam PF01255 Putative undecaprenyl diphosphate synthase 36 256 4.2E-83 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 Gene3D G3DSA:3.40.50.720 1 123 1.4E-51 T 12-10-2018 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.627 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 SUPERFAMILY SSF51735 2 122 1.15E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 3.0E-40 T 12-10-2018 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 3.0E-40 T 12-10-2018 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 3.0E-40 T 12-10-2018 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 3.0E-40 T 12-10-2018 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 Pfam PF00549 CoA-ligase 151 262 3.0E-18 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 Pfam PF02629 CoA binding domain 6 99 2.8E-29 T 12-10-2018 IPR003781 CoA-binding GO:0048037 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 SMART SM00881 4 100 2.9E-33 T 12-10-2018 IPR003781 CoA-binding GO:0048037 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 SUPERFAMILY SSF52210 123 286 3.79E-55 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 Gene3D G3DSA:3.40.50.261 124 289 2.4E-72 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 2.0E-147 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 HW35_16730 ea4b25fc5deffe0afe4b5a41cb8ab529 300 PIRSF PIRSF001553 1 291 4.8E-134 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 HW35_07765 ab9c61fba96c09aec15bb90d3bd98de2 284 SUPERFAMILY SSF53697 95 279 9.74E-39 T 12-10-2018 HW35_07765 ab9c61fba96c09aec15bb90d3bd98de2 284 Gene3D G3DSA:3.40.50.10490 97 282 5.3E-44 T 12-10-2018 HW35_07765 ab9c61fba96c09aec15bb90d3bd98de2 284 Pfam PF01380 SIS domain 128 257 9.9E-24 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HW35_07765 ab9c61fba96c09aec15bb90d3bd98de2 284 Gene3D G3DSA:1.10.10.10 2 82 4.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_07765 ab9c61fba96c09aec15bb90d3bd98de2 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 79 6.5E-21 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 HW35_07765 ab9c61fba96c09aec15bb90d3bd98de2 284 SUPERFAMILY SSF46689 7 78 1.42E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_05990 4b91c7537dacb8690b5a0da159bf3d9e 92 Pfam PF14165 YtzH-like protein 3 88 1.2E-37 T 12-10-2018 IPR025547 YtzH-like protein HW35_17590 376f2baad02ad2b523415ef55c66ad11 366 Gene3D G3DSA:3.30.390.10 1 355 5.6E-115 T 12-10-2018 IPR029017 Enolase-like, N-terminal HW35_17590 376f2baad02ad2b523415ef55c66ad11 366 SUPERFAMILY SSF54826 1 125 2.83E-32 T 12-10-2018 HW35_17590 376f2baad02ad2b523415ef55c66ad11 366 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 6 124 3.7E-17 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain HW35_17590 376f2baad02ad2b523415ef55c66ad11 366 SMART SM00922 141 240 4.3E-26 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal HW35_17590 376f2baad02ad2b523415ef55c66ad11 366 Pfam PF13378 Enolase C-terminal domain-like 144 355 1.2E-48 T 12-10-2018 IPR029065 Enolase C-terminal domain-like HW35_17590 376f2baad02ad2b523415ef55c66ad11 366 Gene3D G3DSA:3.20.20.120 116 353 5.6E-115 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily HW35_17590 376f2baad02ad2b523415ef55c66ad11 366 SUPERFAMILY SSF51604 127 355 9.56E-65 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily HW35_10150 2e831f93502eac74c7153384a27e3d6b 209 Pfam PF02223 Thymidylate kinase 9 194 1.9E-52 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 HW35_10150 2e831f93502eac74c7153384a27e3d6b 209 ProSitePatterns PS01331 Thymidylate kinase signature. 90 102 - T 12-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 HW35_10150 2e831f93502eac74c7153384a27e3d6b 209 SUPERFAMILY SSF52540 1 205 8.04E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10150 2e831f93502eac74c7153384a27e3d6b 209 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 194 6.4E-62 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 HW35_10150 2e831f93502eac74c7153384a27e3d6b 209 Gene3D G3DSA:3.40.50.300 2 205 1.6E-65 T 12-10-2018 HW35_10150 2e831f93502eac74c7153384a27e3d6b 209 Hamap MF_00165 Thymidylate kinase [tmk]. 5 204 31.455 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 SUPERFAMILY SSF52794 400 484 5.75E-6 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 542 680 3.9E-25 T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 Pfam PF00874 PRD domain 195 278 6.5E-6 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 Pfam PF00874 PRD domain 301 389 4.3E-16 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 Gene3D G3DSA:3.40.930.10 538 683 3.2E-41 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 Gene3D G3DSA:3.40.50.2300 401 486 1.7E-6 T 12-10-2018 HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 Gene3D G3DSA:1.10.1790.10 294 392 3.9E-10 T 12-10-2018 HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 SUPERFAMILY SSF63520 176 278 1.06E-6 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 SUPERFAMILY SSF55804 538 680 1.22E-27 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 Pfam PF05043 Mga helix-turn-helix domain 91 166 9.6E-6 T 12-10-2018 IPR007737 Mga helix-turn-helix domain HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 SUPERFAMILY SSF63520 295 394 1.19E-15 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_13225 eb7a1268cffadf70b8de5c81c2bfef3b 684 Gene3D G3DSA:1.10.10.10 74 154 1.8E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_09805 a9794bed2c6212b7dd48fac119be88d0 236 Gene3D G3DSA:1.10.10.10 132 236 8.4E-42 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_09805 a9794bed2c6212b7dd48fac119be88d0 236 SMART SM00448 3 113 4.7E-47 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_09805 a9794bed2c6212b7dd48fac119be88d0 236 SMART SM00862 154 230 3.7E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_09805 a9794bed2c6212b7dd48fac119be88d0 236 Gene3D G3DSA:3.40.50.2300 1 131 2.9E-40 T 12-10-2018 HW35_09805 a9794bed2c6212b7dd48fac119be88d0 236 Pfam PF00072 Response regulator receiver domain 5 114 3.9E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_09805 a9794bed2c6212b7dd48fac119be88d0 236 SUPERFAMILY SSF46894 130 231 1.87E-32 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_09805 a9794bed2c6212b7dd48fac119be88d0 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 1.9E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_09805 a9794bed2c6212b7dd48fac119be88d0 236 SUPERFAMILY SSF52172 2 129 1.99E-44 T 12-10-2018 IPR011006 CheY-like superfamily HW35_03980 54b74bed6850249bf1c998a3454a93e8 132 Pfam PF01029 NusB family 4 126 2.9E-38 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HW35_03980 54b74bed6850249bf1c998a3454a93e8 132 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 130 24.488 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 HW35_03980 54b74bed6850249bf1c998a3454a93e8 132 SUPERFAMILY SSF48013 2 129 3.01E-39 T 12-10-2018 IPR035926 NusB-like superfamily HW35_03980 54b74bed6850249bf1c998a3454a93e8 132 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 128 2.2E-43 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 HW35_03980 54b74bed6850249bf1c998a3454a93e8 132 Gene3D G3DSA:1.10.940.10 1 132 2.9E-47 T 12-10-2018 IPR035926 NusB-like superfamily HW35_14860 b5d37c2e3753ca04ad14c08588199d68 263 Gene3D G3DSA:3.90.226.10 2 201 2.4E-57 T 12-10-2018 HW35_14860 b5d37c2e3753ca04ad14c08588199d68 263 Gene3D G3DSA:1.10.12.10 206 263 3.3E-18 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal HW35_14860 b5d37c2e3753ca04ad14c08588199d68 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 261 5.2E-57 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 HW35_14860 b5d37c2e3753ca04ad14c08588199d68 263 SUPERFAMILY SSF52096 7 261 3.83E-70 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_01630 78bf66dc4319cc88abcc4d5c185b8c3b 104 Gene3D G3DSA:1.10.10.10 4 103 4.9E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_01630 78bf66dc4319cc88abcc4d5c185b8c3b 104 Pfam PF03551 Transcriptional regulator PadR-like family 18 85 1.1E-14 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal HW35_01630 78bf66dc4319cc88abcc4d5c185b8c3b 104 SUPERFAMILY SSF46785 6 101 2.38E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 317 1.7E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Pfam PF07724 AAA domain (Cdc48 subfamily) 536 708 2.2E-58 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 SUPERFAMILY SSF52540 161 469 1.7E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 SMART SM01086 714 803 1.2E-39 T 12-10-2018 IPR019489 Clp ATPase, C-terminal HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Gene3D G3DSA:4.10.860.10 409 467 5.4E-54 T 12-10-2018 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Gene3D G3DSA:1.10.8.60 346 481 5.4E-54 T 12-10-2018 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Gene3D G3DSA:3.40.50.300 490 712 4.3E-92 T 12-10-2018 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 SUPERFAMILY SSF52540 486 800 3.99E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Gene3D G3DSA:3.40.50.300 152 343 6.9E-73 T 12-10-2018 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 615 633 7.7E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 662 7.7E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 541 559 7.7E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 586 604 7.7E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 SUPERFAMILY SSF81923 5 145 1.65E-32 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 2.6E-17 T 12-10-2018 IPR004176 Clp, N-terminal HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.0E-18 T 12-10-2018 IPR004176 Clp, N-terminal HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 SMART SM00382 200 345 1.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 SMART SM00382 537 681 6.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Pfam PF02151 UvrB/uvrC motif 418 452 2.3E-7 T 12-10-2018 IPR001943 UVR domain GO:0005515 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 714 793 9.8E-27 T 12-10-2018 IPR019489 Clp ATPase, C-terminal HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 571 589 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Gene3D G3DSA:1.10.1780.10 1 150 3.8E-62 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 HW35_10580 b0fe0802b39b6273d490d2a4176a2e6c 813 Gene3D G3DSA:1.10.8.60 714 810 2.5E-29 T 12-10-2018 HW35_17080 2dcd4f5ead220bf595339b91595cb60d 314 Gene3D G3DSA:3.10.180.10 66 209 3.2E-117 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_17080 2dcd4f5ead220bf595339b91595cb60d 314 SUPERFAMILY SSF54593 2 288 5.79E-47 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_17080 2dcd4f5ead220bf595339b91595cb60d 314 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 272 2.5E-27 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HW35_17080 2dcd4f5ead220bf595339b91595cb60d 314 Gene3D G3DSA:3.10.180.10 6 302 3.2E-117 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_12005 537ad43a0f47d65b7c56fde04e87ba1c 316 Gene3D G3DSA:1.10.3470.10 2 313 2.0E-62 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_12005 537ad43a0f47d65b7c56fde04e87ba1c 316 Pfam PF01032 FecCD transport family 10 311 5.3E-64 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 HW35_12005 537ad43a0f47d65b7c56fde04e87ba1c 316 SUPERFAMILY SSF81345 5 312 2.22E-66 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 Gene3D G3DSA:2.40.50.140 93 170 8.3E-13 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 PRINTS PR00681 Ribosomal protein S1 signature 81 100 7.6E-51 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 PRINTS PR00681 Ribosomal protein S1 signature 105 121 7.6E-51 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 PRINTS PR00681 Ribosomal protein S1 signature 122 139 7.6E-51 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 PRINTS PR00681 Ribosomal protein S1 signature 151 171 7.6E-51 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 PRINTS PR00681 Ribosomal protein S1 signature 208 229 7.6E-51 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 PRINTS PR00681 Ribosomal protein S1 signature 16 34 7.6E-51 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 PRINTS PR00681 Ribosomal protein S1 signature 286 305 7.6E-51 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 PRINTS PR00681 Ribosomal protein S1 signature 325 343 7.6E-51 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 SUPERFAMILY SSF50249 85 170 3.13E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 Gene3D G3DSA:2.40.50.140 3 92 2.0E-16 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 Gene3D G3DSA:2.40.50.140 267 352 3.4E-26 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 SUPERFAMILY SSF50249 251 348 5.37E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 Gene3D G3DSA:2.40.50.140 171 259 3.3E-31 T 12-10-2018 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 Pfam PF00575 S1 RNA binding domain 270 342 3.2E-22 T 12-10-2018 IPR003029 S1 domain GO:0003676 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 Pfam PF00575 S1 RNA binding domain 185 256 2.8E-26 T 12-10-2018 IPR003029 S1 domain GO:0003676 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 Pfam PF00575 S1 RNA binding domain 98 167 1.4E-15 T 12-10-2018 IPR003029 S1 domain GO:0003676 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 Pfam PF00575 S1 RNA binding domain 13 83 4.3E-10 T 12-10-2018 IPR003029 S1 domain GO:0003676 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 SUPERFAMILY SSF50249 185 273 2.82E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 SUPERFAMILY SSF50249 8 107 1.78E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 SMART SM00316 100 167 4.4E-10 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 SMART SM00316 14 84 3.4E-12 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 SMART SM00316 271 342 5.2E-25 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_03425 b34f57756bd0e4e4a45b897d6e065a0a 379 SMART SM00316 186 256 2.6E-29 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 5.2E-147 T 12-10-2018 IPR002155 Thiolase GO:0016747 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 Gene3D G3DSA:3.40.47.10 128 387 3.4E-154 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 Pfam PF02803 Thiolase, C-terminal domain 268 389 7.4E-51 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 PIRSF PIRSF000429 1 391 1.1E-137 T 12-10-2018 IPR002155 Thiolase GO:0016747 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 Gene3D G3DSA:3.40.47.10 6 274 3.4E-154 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 SUPERFAMILY SSF53901 269 390 2.47E-44 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 SUPERFAMILY SSF53901 1 265 2.36E-78 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 Pfam PF00108 Thiolase, N-terminal domain 5 260 1.1E-79 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 HW35_07155 f2aff28aa6ec340430a1530bda410e25 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 HW35_17060 8526ccd9c6885a60350525aa37793f6c 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 5.3E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_17060 8526ccd9c6885a60350525aa37793f6c 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 5.3E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_17060 8526ccd9c6885a60350525aa37793f6c 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 5.3E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_17060 8526ccd9c6885a60350525aa37793f6c 140 Pfam PF01047 MarR family 35 90 1.8E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_17060 8526ccd9c6885a60350525aa37793f6c 140 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site HW35_17060 8526ccd9c6885a60350525aa37793f6c 140 SUPERFAMILY SSF46785 10 139 2.66E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_17060 8526ccd9c6885a60350525aa37793f6c 140 Gene3D G3DSA:1.10.10.10 4 140 5.5E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_17060 8526ccd9c6885a60350525aa37793f6c 140 SMART SM00347 26 126 7.5E-23 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_12220 1bc344bef11469f226f888909a9759bf 335 Pfam PF01032 FecCD transport family 20 334 5.2E-87 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 HW35_12220 1bc344bef11469f226f888909a9759bf 335 SUPERFAMILY SSF81345 6 334 4.45E-78 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_12220 1bc344bef11469f226f888909a9759bf 335 Gene3D G3DSA:1.10.3470.10 7 335 8.1E-91 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_01275 4303802978faf306c1b13c125df21b44 155 Gene3D G3DSA:3.40.50.2300 1 154 9.6E-59 T 12-10-2018 HW35_01275 4303802978faf306c1b13c125df21b44 155 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 145 2.9E-42 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I HW35_01275 4303802978faf306c1b13c125df21b44 155 PRINTS PR00720 Mammalian LMW phosphotyrosine protein phosphatase signature 67 82 1.6E-6 T 12-10-2018 IPR002115 Protein-tyrosine phosphatase, low molecular weight, mammalian GO:0003993|GO:0004726|GO:0005737|GO:0006470 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 HW35_01275 4303802978faf306c1b13c125df21b44 155 PRINTS PR00720 Mammalian LMW phosphotyrosine protein phosphatase signature 84 104 1.6E-6 T 12-10-2018 IPR002115 Protein-tyrosine phosphatase, low molecular weight, mammalian GO:0003993|GO:0004726|GO:0005737|GO:0006470 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 HW35_01275 4303802978faf306c1b13c125df21b44 155 PRINTS PR00720 Mammalian LMW phosphotyrosine protein phosphatase signature 23 35 1.6E-6 T 12-10-2018 IPR002115 Protein-tyrosine phosphatase, low molecular weight, mammalian GO:0003993|GO:0004726|GO:0005737|GO:0006470 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 HW35_01275 4303802978faf306c1b13c125df21b44 155 SMART SM00226 2 147 2.6E-56 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I HW35_01275 4303802978faf306c1b13c125df21b44 155 SUPERFAMILY SSF52788 2 148 5.89E-49 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily HW35_01275 4303802978faf306c1b13c125df21b44 155 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 121 136 2.1E-18 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HW35_01275 4303802978faf306c1b13c125df21b44 155 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.1E-18 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HW35_01275 4303802978faf306c1b13c125df21b44 155 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 2.1E-18 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HW35_01275 4303802978faf306c1b13c125df21b44 155 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 2.1E-18 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HW35_13400 a31c91fcab65b795733957f69d4651cd 328 SUPERFAMILY SSF81345 23 239 4.05E-6 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_13400 a31c91fcab65b795733957f69d4651cd 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 320 8.2E-43 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 45.669 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 Gene3D G3DSA:3.20.190.10 1 131 4.3E-40 T 12-10-2018 IPR035937 MutM-like, N-terminal HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 SUPERFAMILY SSF81624 2 139 3.01E-44 T 12-10-2018 IPR035937 MutM-like, N-terminal HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 Gene3D G3DSA:1.10.8.50 136 274 3.2E-50 T 12-10-2018 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 SMART SM00898 2 118 4.8E-49 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 Pfam PF06827 Zinc finger found in FPG and IleRS 246 273 2.7E-10 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 12-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 1.2E-32 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 SMART SM01232 134 226 1.3E-46 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 SUPERFAMILY SSF46946 133 223 6.02E-31 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 SUPERFAMILY SSF57716 222 273 2.59E-17 T 12-10-2018 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 223 3.6E-33 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 HW35_05625 6bb673cc7de68cbeff48e878ab89b8f3 275 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 1.7E-112 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 HW35_10255 2c3e92abf42199ff9d931f178d1f6a68 96 SUPERFAMILY SSF160537 1 89 6.41E-34 T 12-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 HW35_10255 2c3e92abf42199ff9d931f178d1f6a68 96 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 28.305 T 12-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 HW35_10255 2c3e92abf42199ff9d931f178d1f6a68 96 Pfam PF04026 SpoVG 1 81 2.6E-36 T 12-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 HW35_10255 2c3e92abf42199ff9d931f178d1f6a68 96 Gene3D G3DSA:3.30.1120.40 1 96 5.3E-39 T 12-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.5E-36 T 12-10-2018 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.5E-36 T 12-10-2018 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.5E-36 T 12-10-2018 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.5E-36 T 12-10-2018 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.5E-36 T 12-10-2018 HW35_07615 24d892d126420348f60d9c80b7e76105 316 Gene3D G3DSA:3.50.50.60 117 240 4.7E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_07615 24d892d126420348f60d9c80b7e76105 316 Gene3D G3DSA:3.50.50.60 8 301 4.7E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_07615 24d892d126420348f60d9c80b7e76105 316 SUPERFAMILY SSF51905 2 302 2.88E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_07615 24d892d126420348f60d9c80b7e76105 316 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 294 3.9E-53 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_07615 24d892d126420348f60d9c80b7e76105 316 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 HW35_07615 24d892d126420348f60d9c80b7e76105 316 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 305 4.1E-122 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 3.6E-70 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 3.6E-70 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 3.6E-70 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 3.6E-70 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 3.6E-70 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 3.6E-70 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 3.6E-70 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 3.6E-70 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_07615 24d892d126420348f60d9c80b7e76105 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 3.6E-70 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_11745 d983b2ffd2c95f5514feec2779bbd31a 581 Gene3D G3DSA:2.30.40.10 21 362 9.2E-82 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_11745 d983b2ffd2c95f5514feec2779bbd31a 581 SUPERFAMILY SSF51556 82 327 2.36E-9 T 12-10-2018 IPR032466 Metal-dependent hydrolase HW35_11745 d983b2ffd2c95f5514feec2779bbd31a 581 Pfam PF01979 Amidohydrolase family 78 362 3.9E-18 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 HW35_11745 d983b2ffd2c95f5514feec2779bbd31a 581 Pfam PF13382 Adenine deaminase C-terminal domain 411 572 1.1E-38 T 12-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 HW35_11745 d983b2ffd2c95f5514feec2779bbd31a 581 SUPERFAMILY SSF51338 21 366 3.24E-12 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_11745 d983b2ffd2c95f5514feec2779bbd31a 581 Gene3D G3DSA:3.20.20.140 82 325 9.2E-82 T 12-10-2018 HW35_07440 e6764d0a930dbacd6de2bac722bc32cb 323 Pfam PF13524 Glycosyl transferases group 1 211 315 3.5E-19 T 12-10-2018 HW35_07440 e6764d0a930dbacd6de2bac722bc32cb 323 Gene3D G3DSA:3.40.50.2000 153 303 1.3E-5 T 12-10-2018 HW35_07440 e6764d0a930dbacd6de2bac722bc32cb 323 SUPERFAMILY SSF53756 1 215 3.14E-5 T 12-10-2018 HW35_07440 e6764d0a930dbacd6de2bac722bc32cb 323 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 81 154 2.2E-13 T 12-10-2018 IPR024542 Domain of unknown function DUF3880 HW35_09125 7e9ceb3dd2d267c0ad5b39364c904c39 72 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 12 62 3.3E-16 T 12-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter HW35_13635 c5da700654182f73d327129239f03f11 133 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 12-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site HW35_13635 c5da700654182f73d327129239f03f11 133 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 121 1.6E-43 T 12-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L HW35_13635 c5da700654182f73d327129239f03f11 133 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 123 2.8E-48 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 HW35_13635 c5da700654182f73d327129239f03f11 133 Gene3D G3DSA:1.10.1200.120 1 124 4.3E-41 T 12-10-2018 IPR036019 Gated mechanosensitive channel HW35_13635 c5da700654182f73d327129239f03f11 133 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 6.2E-12 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 HW35_13635 c5da700654182f73d327129239f03f11 133 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 6.2E-12 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 HW35_13635 c5da700654182f73d327129239f03f11 133 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 6.2E-12 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 HW35_13635 c5da700654182f73d327129239f03f11 133 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 122 23.036 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 HW35_13635 c5da700654182f73d327129239f03f11 133 SUPERFAMILY SSF81330 10 117 1.29E-33 T 12-10-2018 IPR036019 Gated mechanosensitive channel HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 SUPERFAMILY SSF56719 30 485 7.06E-171 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 706 752 1.4E-4 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 655 696 2.2E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 599 2.3E-6 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 606 650 1.8E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 504 526 0.014 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Gene3D G3DSA:2.120.10.90 499 810 6.9E-121 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 470 1.2E-152 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 9 745 0.0 T 12-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 SMART SM00434 10 463 4.5E-261 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Gene3D G3DSA:3.30.1360.40 235 331 8.5E-199 T 12-10-2018 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 6 803 33.703 T 12-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Gene3D G3DSA:3.90.199.10 31 485 8.5E-199 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 SUPERFAMILY SSF101904 499 808 4.32E-97 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 803 1.3E-273 T 12-10-2018 HW35_01030 8c75e4e17e4700fb824f029f31d562c5 810 Gene3D G3DSA:1.10.268.10 368 456 8.5E-199 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 SUPERFAMILY SSF51905 18 238 1.59E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 Gene3D G3DSA:3.30.9.10 102 343 8.3E-132 T 12-10-2018 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 Gene3D G3DSA:3.50.50.60 20 379 8.3E-132 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 Pfam PF01266 FAD dependent oxidoreductase 21 350 7.7E-51 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 403 529 2.0E-20 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 SUPERFAMILY SSF54373 250 342 4.19E-11 T 12-10-2018 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 Gene3D G3DSA:1.10.8.870 419 550 3.1E-38 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 371 381 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 336 342 9.6E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 9.6E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 9.6E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 366 378 9.6E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 9.6E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 HW35_15785 9f0679e1d22ed4f6d58b0162a3e88632 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 9.6E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 HW35_14600 903b702ffa7236763a84ee92056d29d9 631 PIRSF PIRSF000549 1 631 6.0E-267 T 12-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 HW35_14600 903b702ffa7236763a84ee92056d29d9 631 SUPERFAMILY SSF52540 67 464 3.18E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14600 903b702ffa7236763a84ee92056d29d9 631 Pfam PF08298 PrkA AAA domain 22 371 8.0E-154 T 12-10-2018 IPR013153 PrkA AAA domain HW35_14600 903b702ffa7236763a84ee92056d29d9 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 3.9E-94 T 12-10-2018 IPR010650 PrkA C-terminal domain HW35_14600 903b702ffa7236763a84ee92056d29d9 631 SMART SM00763 21 371 1.1E-199 T 12-10-2018 IPR013153 PrkA AAA domain HW35_09915 527f96d9c90950553692a830f62a5ce6 237 Pfam PF04474 Protein of unknown function (DUF554) 4 227 5.5E-73 T 12-10-2018 IPR007563 Protein of unknown function DUF554 HW35_11120 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_11120 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_11120 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_12865 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_12865 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_12865 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_14030 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_14030 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_14030 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_05390 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_05390 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_05390 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_02355 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_02355 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_02355 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_02415 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_02415 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_02415 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_17470 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_17470 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_17470 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_06020 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_06020 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_06020 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_11435 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_11435 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_11435 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_00630 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_00630 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_00630 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_14570 c0e24c2f970c300d9916f5c74d2e7194 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_14570 c0e24c2f970c300d9916f5c74d2e7194 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_14570 c0e24c2f970c300d9916f5c74d2e7194 92 SUPERFAMILY SSF46689 4 89 2.06E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 Pfam PF00696 Amino acid kinase family 3 229 3.1E-57 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 Pfam PF01842 ACT domain 276 313 1.4E-6 T 12-10-2018 IPR002912 ACT domain HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 Pfam PF13840 ACT domain 335 398 2.8E-16 T 12-10-2018 IPR027795 CASTOR, ACT domain HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 1.5E-147 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 401 6.9E-122 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 SUPERFAMILY SSF55021 330 403 5.49E-22 T 12-10-2018 HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 SUPERFAMILY SSF55021 249 325 3.37E-15 T 12-10-2018 HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 PIRSF PIRSF000726 59 406 1.4E-132 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 PIRSF PIRSF000726 1 61 8.0E-22 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 Gene3D G3DSA:3.40.1160.10 1 253 5.4E-93 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 SUPERFAMILY SSF53633 3 242 1.24E-75 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 Gene3D G3DSA:3.30.70.260 260 337 1.0E-50 T 12-10-2018 HW35_05435 3334d2866b0f629a7bbbb8d5bc51de0d 406 Gene3D G3DSA:3.30.70.260 254 402 1.0E-50 T 12-10-2018 HW35_15395 20cb49c92174fdf8c83c79847fe52691 299 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 132 146 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_15395 20cb49c92174fdf8c83c79847fe52691 299 SUPERFAMILY SSF55120 76 293 2.88E-69 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_15395 20cb49c92174fdf8c83c79847fe52691 299 Gene3D G3DSA:3.30.2350.10 81 296 1.1E-65 T 12-10-2018 HW35_15395 20cb49c92174fdf8c83c79847fe52691 299 Pfam PF00849 RNA pseudouridylate synthase 90 239 1.2E-27 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_15395 20cb49c92174fdf8c83c79847fe52691 299 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 29 293 2.8E-70 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_17145 f7cf96147ae54db6365eef91369962e7 76 Gene3D G3DSA:2.30.30.100 1 74 2.6E-35 T 12-10-2018 HW35_17145 f7cf96147ae54db6365eef91369962e7 76 SUPERFAMILY SSF50182 6 64 4.09E-24 T 12-10-2018 IPR010920 LSM domain superfamily HW35_17145 f7cf96147ae54db6365eef91369962e7 76 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 29.557 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 HW35_17145 f7cf96147ae54db6365eef91369962e7 76 Pfam PF17209 Hfq protein 7 69 4.2E-33 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 HW35_17145 f7cf96147ae54db6365eef91369962e7 76 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 4.1E-32 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 4 206 38.572 T 12-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 119 205 1.2E-19 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 2 105 29.55 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 100 2.3E-35 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 SUPERFAMILY SSF101386 117 205 1.16E-26 T 12-10-2018 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 115 201 21.148 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 118 201 1.9E-32 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 Gene3D G3DSA:1.10.287.1080 114 207 1.2E-33 T 12-10-2018 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 SUPERFAMILY SSF141734 3 106 3.53E-47 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 Gene3D G3DSA:3.10.20.400 1 92 1.4E-41 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 HW35_07630 10f429a8df4ac6c2a5e7c333bf4976a9 209 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 51 100 9.0E-20 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 HW35_05800 abbeb4db74bea18c418c6d1aa66ef08c 327 Gene3D G3DSA:1.10.150.470 2 85 2.9E-27 T 12-10-2018 HW35_05800 abbeb4db74bea18c418c6d1aa66ef08c 327 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 120 134 4.0E-7 T 12-10-2018 HW35_05800 abbeb4db74bea18c418c6d1aa66ef08c 327 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 215 239 4.0E-7 T 12-10-2018 HW35_05800 abbeb4db74bea18c418c6d1aa66ef08c 327 Pfam PF02384 N-6 DNA Methylase 96 317 1.1E-19 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HW35_05800 abbeb4db74bea18c418c6d1aa66ef08c 327 SUPERFAMILY SSF53335 17 316 1.04E-51 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_05800 abbeb4db74bea18c418c6d1aa66ef08c 327 PIRSF PIRSF026567 1 327 1.1E-141 T 12-10-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted HW35_05800 abbeb4db74bea18c418c6d1aa66ef08c 327 Gene3D G3DSA:3.40.50.150 87 326 3.3E-56 T 12-10-2018 HW35_05020 bf44ce612c4af128567b0ea0017c7424 285 SUPERFAMILY SSF53850 2 184 5.03E-55 T 12-10-2018 HW35_05020 bf44ce612c4af128567b0ea0017c7424 285 Gene3D G3DSA:3.30.70.260 193 282 1.5E-25 T 12-10-2018 HW35_05020 bf44ce612c4af128567b0ea0017c7424 285 Gene3D G3DSA:3.40.190.10 83 172 4.0E-55 T 12-10-2018 HW35_05020 bf44ce612c4af128567b0ea0017c7424 285 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 227 234 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HW35_05020 bf44ce612c4af128567b0ea0017c7424 285 Pfam PF00800 Prephenate dehydratase 3 184 2.3E-59 T 12-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HW35_05020 bf44ce612c4af128567b0ea0017c7424 285 Gene3D G3DSA:3.40.190.10 5 180 4.0E-55 T 12-10-2018 HW35_05020 bf44ce612c4af128567b0ea0017c7424 285 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 158 180 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HW35_05020 bf44ce612c4af128567b0ea0017c7424 285 SUPERFAMILY SSF55021 191 279 3.09E-24 T 12-10-2018 HW35_05020 bf44ce612c4af128567b0ea0017c7424 285 PIRSF PIRSF001500 1 282 1.1E-73 T 12-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HW35_05490 844d88b69c185191707441ed53570442 571 Pfam PF14716 Helix-hairpin-helix domain 6 70 8.6E-19 T 12-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain HW35_05490 844d88b69c185191707441ed53570442 571 Gene3D G3DSA:3.30.210.10 261 325 2.2E-18 T 12-10-2018 IPR037160 DNA polymerase, thumb domain superfamily HW35_05490 844d88b69c185191707441ed53570442 571 SUPERFAMILY SSF89550 336 562 1.7E-57 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HW35_05490 844d88b69c185191707441ed53570442 571 PIRSF PIRSF005047 3 571 1.6E-243 T 12-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_05490 844d88b69c185191707441ed53570442 571 Pfam PF02811 PHP domain 339 490 1.9E-9 T 12-10-2018 IPR004013 PHP domain GO:0003824 HW35_05490 844d88b69c185191707441ed53570442 571 SUPERFAMILY SSF158702 54 145 2.88E-7 T 12-10-2018 HW35_05490 844d88b69c185191707441ed53570442 571 Gene3D G3DSA:3.20.20.140 328 571 3.9E-78 T 12-10-2018 HW35_05490 844d88b69c185191707441ed53570442 571 SMART SM00278 50 69 160.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HW35_05490 844d88b69c185191707441ed53570442 571 SMART SM00278 90 109 27.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HW35_05490 844d88b69c185191707441ed53570442 571 SMART SM00278 125 144 39.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HW35_05490 844d88b69c185191707441ed53570442 571 Gene3D G3DSA:3.30.460.10 154 260 2.9E-23 T 12-10-2018 HW35_05490 844d88b69c185191707441ed53570442 571 SMART SM00483 2 316 7.7E-79 T 12-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 HW35_05490 844d88b69c185191707441ed53570442 571 SUPERFAMILY SSF47802 6 83 6.28E-19 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily HW35_05490 844d88b69c185191707441ed53570442 571 SMART SM00481 338 417 9.3E-23 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HW35_05490 844d88b69c185191707441ed53570442 571 SUPERFAMILY SSF81301 154 316 3.27E-45 T 12-10-2018 HW35_05490 844d88b69c185191707441ed53570442 571 Gene3D G3DSA:1.10.150.110 1 84 1.9E-18 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily HW35_05490 844d88b69c185191707441ed53570442 571 Pfam PF14791 DNA polymerase beta thumb 255 316 6.9E-20 T 12-10-2018 IPR029398 DNA polymerase beta, thumb domain HW35_05490 844d88b69c185191707441ed53570442 571 Pfam PF14520 Helix-hairpin-helix domain 92 145 1.0E-6 T 12-10-2018 HW35_05490 844d88b69c185191707441ed53570442 571 Gene3D G3DSA:1.10.150.20 85 149 1.5E-19 T 12-10-2018 HW35_03930 b7ecdb0ecd6eb16835a12ed464c4b703 242 Gene3D G3DSA:3.20.20.190 1 238 2.9E-76 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 HW35_03930 b7ecdb0ecd6eb16835a12ed464c4b703 242 SUPERFAMILY SSF51695 2 235 8.58E-68 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 HW35_03930 b7ecdb0ecd6eb16835a12ed464c4b703 242 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 229 2.5E-46 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 HW35_16230 132019801127954a9cc04896d45fefa1 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.214 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16230 132019801127954a9cc04896d45fefa1 57 SUPERFAMILY SSF57829 1 55 2.81E-22 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 HW35_16230 132019801127954a9cc04896d45fefa1 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.6E-28 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16230 132019801127954a9cc04896d45fefa1 57 Pfam PF01783 Ribosomal L32p protein family 2 56 6.9E-28 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_17575 d8669a8baebbf2119368fdb7b8ee97d8 332 SMART SM00382 33 241 4.2E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_17575 d8669a8baebbf2119368fdb7b8ee97d8 332 Gene3D G3DSA:3.40.50.300 1 332 3.3E-107 T 12-10-2018 HW35_17575 d8669a8baebbf2119368fdb7b8ee97d8 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 7.6E-20 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_17575 d8669a8baebbf2119368fdb7b8ee97d8 332 SUPERFAMILY SSF52540 4 254 1.44E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17575 d8669a8baebbf2119368fdb7b8ee97d8 332 Pfam PF00005 ABC transporter 25 183 2.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_17575 d8669a8baebbf2119368fdb7b8ee97d8 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 3.7E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_17575 d8669a8baebbf2119368fdb7b8ee97d8 332 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 SUPERFAMILY SSF51735 122 278 3.28E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 39.867 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.8E-44 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 3.2E-85 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 3.2E-85 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 3.2E-85 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 3.2E-85 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 3.2E-85 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 3.2E-85 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 3.2E-85 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 SUPERFAMILY SSF53223 1 121 4.12E-43 T 12-10-2018 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 4.0E-73 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 Gene3D G3DSA:3.40.50.720 6 258 2.0E-119 T 12-10-2018 HW35_03975 6ea75b83ecc8ce6cf99844a25f9a95c7 284 Gene3D G3DSA:3.40.50.10860 8 275 2.0E-119 T 12-10-2018 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 SUPERFAMILY SSF48150 13 231 8.17E-77 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 Pfam PF00633 Helix-hairpin-helix motif 109 137 2.5E-10 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 Gene3D G3DSA:3.90.79.10 238 367 2.3E-30 T 12-10-2018 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 44 178 9.3E-18 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 Gene3D G3DSA:1.10.340.30 30 141 4.1E-92 T 12-10-2018 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 SMART SM00478 48 199 7.0E-57 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 Gene3D G3DSA:1.10.1670.10 19 222 4.1E-92 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 16 280 8.8E-111 T 12-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 Pfam PF14815 NUDIX domain 244 358 4.6E-21 T 12-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 SMART SM00525 200 220 2.6E-4 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 HW35_14240 fdfa8eecf0baeb0ef357406843fdf94b 368 SUPERFAMILY SSF55811 240 362 9.0E-25 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 HW35_15005 b0158773f9d601b2b76f13dba74a011d 518 Gene3D G3DSA:3.30.300.310 417 518 1.7E-34 T 12-10-2018 HW35_15005 b0158773f9d601b2b76f13dba74a011d 518 PRINTS PR00154 AMP-binding signature 171 182 7.0E-5 T 12-10-2018 IPR020459 AMP-binding HW35_15005 b0158773f9d601b2b76f13dba74a011d 518 PRINTS PR00154 AMP-binding signature 183 191 7.0E-5 T 12-10-2018 IPR020459 AMP-binding HW35_15005 b0158773f9d601b2b76f13dba74a011d 518 SUPERFAMILY SSF56801 5 515 2.22E-167 T 12-10-2018 HW35_15005 b0158773f9d601b2b76f13dba74a011d 518 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 504 2.1E-20 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_15005 b0158773f9d601b2b76f13dba74a011d 518 Gene3D G3DSA:3.40.50.12780 1 414 7.7E-129 T 12-10-2018 HW35_15005 b0158773f9d601b2b76f13dba74a011d 518 Pfam PF00501 AMP-binding enzyme 8 421 1.7E-118 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_15005 b0158773f9d601b2b76f13dba74a011d 518 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_17415 93952ffe55d2c984316e8ae19dc43037 416 Pfam PF07690 Major Facilitator Superfamily 20 360 4.7E-52 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_17415 93952ffe55d2c984316e8ae19dc43037 416 Gene3D G3DSA:1.20.1250.20 3 409 3.1E-64 T 12-10-2018 HW35_17415 93952ffe55d2c984316e8ae19dc43037 416 SUPERFAMILY SSF103473 6 406 7.85E-66 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_17415 93952ffe55d2c984316e8ae19dc43037 416 PRINTS PR01035 Tetracycline resistance protein signature 168 188 8.1E-9 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_17415 93952ffe55d2c984316e8ae19dc43037 416 PRINTS PR01035 Tetracycline resistance protein signature 344 367 8.1E-9 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_17415 93952ffe55d2c984316e8ae19dc43037 416 PRINTS PR01035 Tetracycline resistance protein signature 20 36 8.1E-9 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_17415 93952ffe55d2c984316e8ae19dc43037 416 PRINTS PR01035 Tetracycline resistance protein signature 140 162 8.1E-9 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_17415 93952ffe55d2c984316e8ae19dc43037 416 PRINTS PR01035 Tetracycline resistance protein signature 283 304 8.1E-9 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_00745 c8add5f1e3c8724bcd3ff15b96612685 661 Gene3D G3DSA:3.30.300.30 528 642 8.1E-15 T 12-10-2018 HW35_00745 c8add5f1e3c8724bcd3ff15b96612685 661 Pfam PF00501 AMP-binding enzyme 104 531 3.8E-48 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_00745 c8add5f1e3c8724bcd3ff15b96612685 661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 273 284 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_00745 c8add5f1e3c8724bcd3ff15b96612685 661 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 9 656 3.8E-259 T 12-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 HW35_00745 c8add5f1e3c8724bcd3ff15b96612685 661 Pfam PF13193 AMP-binding enzyme C-terminal domain 540 618 2.0E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_00745 c8add5f1e3c8724bcd3ff15b96612685 661 Gene3D G3DSA:3.40.50.12780 79 525 1.8E-58 T 12-10-2018 HW35_00745 c8add5f1e3c8724bcd3ff15b96612685 661 SUPERFAMILY SSF56801 41 634 3.27E-127 T 12-10-2018 HW35_00745 c8add5f1e3c8724bcd3ff15b96612685 661 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 42 96 3.0E-14 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 HW35_04375 3302707b8c4281abad4bcd84b8a5bb3d 297 SUPERFAMILY SSF51658 2 295 2.75E-103 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily HW35_04375 3302707b8c4281abad4bcd84b8a5bb3d 297 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 HW35_04375 3302707b8c4281abad4bcd84b8a5bb3d 297 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 HW35_04375 3302707b8c4281abad4bcd84b8a5bb3d 297 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 285 43.029 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 HW35_04375 3302707b8c4281abad4bcd84b8a5bb3d 297 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 HW35_04375 3302707b8c4281abad4bcd84b8a5bb3d 297 SMART SM00518 3 285 9.0E-128 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 HW35_04375 3302707b8c4281abad4bcd84b8a5bb3d 297 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 282 1.5E-103 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 HW35_04375 3302707b8c4281abad4bcd84b8a5bb3d 297 Gene3D G3DSA:3.20.20.150 1 297 1.1E-105 T 12-10-2018 HW35_04375 3302707b8c4281abad4bcd84b8a5bb3d 297 Pfam PF01261 Xylose isomerase-like TIM barrel 21 237 5.0E-38 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 240 255 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 SMART SM00382 175 318 2.2E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 Gene3D G3DSA:3.30.450.20 5 119 4.1E-16 T 12-10-2018 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 179 192 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 Gene3D G3DSA:3.40.50.300 140 324 6.9E-59 T 12-10-2018 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 367 376 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 Pfam PF00158 Sigma-54 interaction domain 157 319 3.2E-61 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 Pfam PF08448 PAS fold 16 119 3.1E-9 T 12-10-2018 IPR013656 PAS fold-4 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 Gene3D G3DSA:1.10.8.60 325 392 1.8E-23 T 12-10-2018 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 SUPERFAMILY SSF52540 157 396 1.09E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 Gene3D G3DSA:1.10.10.60 399 464 3.4E-13 T 12-10-2018 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 428 445 2.5E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 445 465 2.5E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 SUPERFAMILY SSF55785 9 114 2.62E-12 T 12-10-2018 IPR035965 PAS domain superfamily HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 SUPERFAMILY SSF46689 367 461 5.73E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 129 6.7E-8 T 12-10-2018 IPR000014 PAS domain HW35_02720 c6453ec4ce18ae9b326f642f0ce8d301 466 Pfam PF02954 Bacterial regulatory protein, Fis family 422 461 2.6E-14 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HW35_02000 47a49859bf4ac5e0d3d377d46bd49091 861 SUPERFAMILY SSF52540 372 644 3.46E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02000 47a49859bf4ac5e0d3d377d46bd49091 861 Gene3D G3DSA:3.40.50.300 373 514 1.4E-107 T 12-10-2018 HW35_02000 47a49859bf4ac5e0d3d377d46bd49091 861 Gene3D G3DSA:1.20.272.40 660 731 1.4E-107 T 12-10-2018 HW35_02000 47a49859bf4ac5e0d3d377d46bd49091 861 Gene3D G3DSA:3.40.50.300 515 659 1.4E-107 T 12-10-2018 HW35_02000 47a49859bf4ac5e0d3d377d46bd49091 861 Pfam PF00271 Helicase conserved C-terminal domain 529 635 8.9E-14 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_02000 47a49859bf4ac5e0d3d377d46bd49091 861 SMART SM00490 546 635 2.6E-22 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_12480 720a3cee33b9e3def55f231b82a2a7da 266 SMART SM00257 26 69 8.6E-11 T 12-10-2018 IPR018392 LysM domain HW35_12480 720a3cee33b9e3def55f231b82a2a7da 266 SMART SM00257 73 116 9.1E-15 T 12-10-2018 IPR018392 LysM domain HW35_12480 720a3cee33b9e3def55f231b82a2a7da 266 SUPERFAMILY SSF54106 25 68 7.98E-8 T 12-10-2018 HW35_12480 720a3cee33b9e3def55f231b82a2a7da 266 SUPERFAMILY SSF50685 207 252 9.42E-8 T 12-10-2018 IPR036908 RlpA-like domain superfamily HW35_12480 720a3cee33b9e3def55f231b82a2a7da 266 Gene3D G3DSA:3.10.350.10 12 71 3.6E-12 T 12-10-2018 IPR036779 LysM domain superfamily HW35_12480 720a3cee33b9e3def55f231b82a2a7da 266 Pfam PF01476 LysM domain 74 115 9.6E-16 T 12-10-2018 IPR018392 LysM domain HW35_12480 720a3cee33b9e3def55f231b82a2a7da 266 Pfam PF01476 LysM domain 27 68 2.6E-11 T 12-10-2018 IPR018392 LysM domain HW35_12480 720a3cee33b9e3def55f231b82a2a7da 266 SUPERFAMILY SSF54106 73 115 2.09E-12 T 12-10-2018 HW35_12480 720a3cee33b9e3def55f231b82a2a7da 266 Pfam PF06725 3D domain 206 266 6.7E-21 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 HW35_12480 720a3cee33b9e3def55f231b82a2a7da 266 Gene3D G3DSA:3.10.350.10 72 124 5.9E-20 T 12-10-2018 IPR036779 LysM domain superfamily HW35_00075 726405522636efa8c075e44e3e408daa 155 SUPERFAMILY SSF52121 4 154 1.96E-64 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HW35_00075 726405522636efa8c075e44e3e408daa 155 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 2.7E-60 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HW35_00075 726405522636efa8c075e44e3e408daa 155 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 3.9E-62 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HW35_00075 726405522636efa8c075e44e3e408daa 155 Gene3D G3DSA:3.40.50.960 3 155 1.1E-67 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HW35_00075 726405522636efa8c075e44e3e408daa 155 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 9 154 32.019 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HW35_13395 5a81309856d54d02961ff5cb23b3ab54 494 Pfam PF00005 ABC transporter 14 168 5.0E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_13395 5a81309856d54d02961ff5cb23b3ab54 494 SMART SM00382 276 470 1.6E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_13395 5a81309856d54d02961ff5cb23b3ab54 494 SMART SM00382 23 216 6.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_13395 5a81309856d54d02961ff5cb23b3ab54 494 Gene3D G3DSA:3.40.50.300 1 237 4.7E-54 T 12-10-2018 HW35_13395 5a81309856d54d02961ff5cb23b3ab54 494 SUPERFAMILY SSF52540 243 480 9.73E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13395 5a81309856d54d02961ff5cb23b3ab54 494 Pfam PF00005 ABC transporter 267 422 1.1E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_13395 5a81309856d54d02961ff5cb23b3ab54 494 SUPERFAMILY SSF52540 2 225 5.67E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13395 5a81309856d54d02961ff5cb23b3ab54 494 ProSitePatterns PS00211 ABC transporters family signature. 395 409 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_13395 5a81309856d54d02961ff5cb23b3ab54 494 Gene3D G3DSA:3.40.50.300 257 491 7.9E-46 T 12-10-2018 HW35_01260 335b6e63fd94087ecc88d9b203190f3d 306 Pfam PF14572 Phosphoribosyl synthetase-associated domain 196 305 5.4E-28 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HW35_01260 335b6e63fd94087ecc88d9b203190f3d 306 Gene3D G3DSA:3.40.50.2020 2 294 1.5E-121 T 12-10-2018 HW35_01260 335b6e63fd94087ecc88d9b203190f3d 306 Gene3D G3DSA:3.40.50.2020 142 282 1.5E-121 T 12-10-2018 HW35_01260 335b6e63fd94087ecc88d9b203190f3d 306 SMART SM01400 2 115 6.1E-75 T 12-10-2018 HW35_01260 335b6e63fd94087ecc88d9b203190f3d 306 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 115 5.7E-50 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HW35_01260 335b6e63fd94087ecc88d9b203190f3d 306 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 1 306 46.903 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 HW35_01260 335b6e63fd94087ecc88d9b203190f3d 306 SUPERFAMILY SSF53271 64 298 7.9E-62 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_01260 335b6e63fd94087ecc88d9b203190f3d 306 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 2 306 1.5E-121 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 47.573 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 Gene3D G3DSA:3.10.20.580 449 555 4.2E-40 T 12-10-2018 HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 360 407 8.4E-9 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 SUPERFAMILY SSF56281 11 423 3.24E-94 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 Gene3D G3DSA:3.60.15.10 12 442 1.7E-188 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 553 1.7E-228 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 Gene3D G3DSA:3.40.50.10710 207 357 1.7E-188 T 12-10-2018 HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 12-10-2018 IPR001587 Ribonuclease J, conserved site HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 PIRSF PIRSF004803 1 555 1.5E-243 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 Pfam PF00753 Metallo-beta-lactamase superfamily 20 167 1.0E-14 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_15915 cd5b9f7cab3fb8445f178c2245983134 555 SMART SM00849 21 215 2.0E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_10355 a9b0a2267adbef93c056268004d83cb5 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 174 2.3E-69 T 12-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 HW35_10355 a9b0a2267adbef93c056268004d83cb5 180 Pfam PF00156 Phosphoribosyl transferase domain 14 160 3.6E-25 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HW35_10355 a9b0a2267adbef93c056268004d83cb5 180 SUPERFAMILY SSF53271 4 178 3.02E-61 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_10355 a9b0a2267adbef93c056268004d83cb5 180 Gene3D G3DSA:3.40.50.2020 1 180 2.0E-68 T 12-10-2018 HW35_15255 435b7737f38c90e54c43a7d97c7bf34b 412 Gene3D G3DSA:3.40.47.10 256 400 2.1E-58 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_15255 435b7737f38c90e54c43a7d97c7bf34b 412 SUPERFAMILY SSF53901 4 251 1.15E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_15255 435b7737f38c90e54c43a7d97c7bf34b 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 1.1E-61 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal HW35_15255 435b7737f38c90e54c43a7d97c7bf34b 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 8.9E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal HW35_15255 435b7737f38c90e54c43a7d97c7bf34b 412 SMART SM00825 Beta-ketoacyl synthase 6 412 3.0E-16 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain HW35_15255 435b7737f38c90e54c43a7d97c7bf34b 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site HW35_15255 435b7737f38c90e54c43a7d97c7bf34b 412 SUPERFAMILY SSF53901 214 411 3.13E-79 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_15255 435b7737f38c90e54c43a7d97c7bf34b 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 1.3E-203 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 HW35_15255 435b7737f38c90e54c43a7d97c7bf34b 412 Gene3D G3DSA:3.40.47.10 1 254 4.7E-105 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_15255 435b7737f38c90e54c43a7d97c7bf34b 412 PIRSF PIRSF000447 1 412 6.1E-190 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 HW35_03860 cc78fff500696d1b848818b3fc105b6c 145 Gene3D G3DSA:3.40.30.10 25 142 8.1E-53 T 12-10-2018 HW35_03860 cc78fff500696d1b848818b3fc105b6c 145 Pfam PF06491 Disulphide isomerase 8 142 2.4E-61 T 12-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family HW35_03860 cc78fff500696d1b848818b3fc105b6c 145 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 142 2.8E-62 T 12-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family HW35_16870 7591b4ccb627865ce429956954dd9895 412 SUPERFAMILY SSF63411 4 204 1.18E-59 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HW35_16870 7591b4ccb627865ce429956954dd9895 412 Gene3D G3DSA:3.30.830.10 218 412 4.2E-60 T 12-10-2018 HW35_16870 7591b4ccb627865ce429956954dd9895 412 Pfam PF05193 Peptidase M16 inactive domain 166 338 1.0E-40 T 12-10-2018 IPR007863 Peptidase M16, C-terminal HW35_16870 7591b4ccb627865ce429956954dd9895 412 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 2.1E-46 T 12-10-2018 IPR011765 Peptidase M16, N-terminal HW35_16870 7591b4ccb627865ce429956954dd9895 412 Gene3D G3DSA:3.30.830.10 1 212 1.8E-78 T 12-10-2018 HW35_16870 7591b4ccb627865ce429956954dd9895 412 SUPERFAMILY SSF63411 226 401 1.04E-47 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HW35_16870 7591b4ccb627865ce429956954dd9895 412 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 12-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 HW35_10405 f71f5e16d4935e6785a4e4aa6404984f 66 Gene3D G3DSA:1.10.260.40 2 66 6.0E-17 T 12-10-2018 HW35_10405 f71f5e16d4935e6785a4e4aa6404984f 66 Pfam PF01381 Helix-turn-helix 10 63 3.7E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_10405 f71f5e16d4935e6785a4e4aa6404984f 66 SMART SM00530 9 64 4.1E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_10405 f71f5e16d4935e6785a4e4aa6404984f 66 SUPERFAMILY SSF47413 4 65 3.75E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_05210 fe69bbe1c93be20cb6ff449a7fd0153c 419 SUPERFAMILY SSF56672 16 356 4.06E-62 T 12-10-2018 HW35_05210 fe69bbe1c93be20cb6ff449a7fd0153c 419 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 1.4E-133 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_05210 fe69bbe1c93be20cb6ff449a7fd0153c 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05210 fe69bbe1c93be20cb6ff449a7fd0153c 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05210 fe69bbe1c93be20cb6ff449a7fd0153c 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05210 fe69bbe1c93be20cb6ff449a7fd0153c 419 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 4.5E-47 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_05210 fe69bbe1c93be20cb6ff449a7fd0153c 419 Pfam PF08388 Group II intron, maturase-specific domain 288 360 6.7E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_05910 5cdfc71b7b27d56bd6e69f22c4931073 215 SUPERFAMILY SSF55021 137 207 8.4E-9 T 12-10-2018 HW35_05910 5cdfc71b7b27d56bd6e69f22c4931073 215 SUPERFAMILY SSF54631 2 130 1.21E-29 T 12-10-2018 HW35_05910 5cdfc71b7b27d56bd6e69f22c4931073 215 Pfam PF00571 CBS domain 76 127 2.4E-9 T 12-10-2018 IPR000644 CBS domain HW35_05910 5cdfc71b7b27d56bd6e69f22c4931073 215 Pfam PF00571 CBS domain 3 56 2.6E-10 T 12-10-2018 IPR000644 CBS domain HW35_05910 5cdfc71b7b27d56bd6e69f22c4931073 215 SMART SM00116 81 128 3.9E-11 T 12-10-2018 IPR000644 CBS domain HW35_05910 5cdfc71b7b27d56bd6e69f22c4931073 215 SMART SM00116 10 58 1.7E-6 T 12-10-2018 IPR000644 CBS domain HW35_05910 5cdfc71b7b27d56bd6e69f22c4931073 215 Pfam PF01842 ACT domain 139 179 2.2E-6 T 12-10-2018 IPR002912 ACT domain HW35_05910 5cdfc71b7b27d56bd6e69f22c4931073 215 Gene3D G3DSA:3.10.580.10 1 147 2.0E-38 T 12-10-2018 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 Pfam PF01168 Alanine racemase, N-terminal domain 15 232 4.8E-69 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 TIGRFAM TIGR00492 alr: alanine racemase 9 371 3.0E-131 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 Pfam PF00842 Alanine racemase, C-terminal domain 248 371 9.3E-45 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 Gene3D G3DSA:3.20.20.10 17 236 1.4E-133 T 12-10-2018 IPR029066 PLP-binding barrel HW35_11420 33c39d1a4571da57eeabe910598c7020 385 Gene3D G3DSA:2.40.37.10 15 369 1.4E-133 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 SUPERFAMILY SSF51419 15 238 7.1E-63 T 12-10-2018 IPR029066 PLP-binding barrel HW35_11420 33c39d1a4571da57eeabe910598c7020 385 Hamap MF_01201 Alanine racemase. 8 372 35.477 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 SUPERFAMILY SSF50621 242 383 1.36E-50 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 39 49 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 PRINTS PR00992 Alanine racemase signature 280 295 1.9E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 PRINTS PR00992 Alanine racemase signature 354 367 1.9E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 PRINTS PR00992 Alanine racemase signature 70 88 1.9E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 PRINTS PR00992 Alanine racemase signature 205 232 1.9E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 PRINTS PR00992 Alanine racemase signature 263 278 1.9E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 PRINTS PR00992 Alanine racemase signature 300 317 1.9E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 PRINTS PR00992 Alanine racemase signature 34 50 1.9E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 PRINTS PR00992 Alanine racemase signature 165 176 1.9E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 PRINTS PR00992 Alanine racemase signature 130 142 1.9E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_11420 33c39d1a4571da57eeabe910598c7020 385 SMART SM01005 247 372 1.8E-67 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_17580 a7ac8c9cfd7c2ffc551fe63706acbd62 542 Gene3D G3DSA:3.90.76.10 75 197 1.0E-176 T 12-10-2018 HW35_17580 a7ac8c9cfd7c2ffc551fe63706acbd62 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 464 1.1E-86 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain HW35_17580 a7ac8c9cfd7c2ffc551fe63706acbd62 542 Gene3D G3DSA:3.40.190.10 54 529 1.0E-176 T 12-10-2018 HW35_17580 a7ac8c9cfd7c2ffc551fe63706acbd62 542 SUPERFAMILY SSF53850 40 535 1.99E-139 T 12-10-2018 HW35_17580 a7ac8c9cfd7c2ffc551fe63706acbd62 542 PIRSF PIRSF002741 1 541 1.4E-126 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HW35_17580 a7ac8c9cfd7c2ffc551fe63706acbd62 542 Gene3D G3DSA:3.10.105.10 297 515 1.0E-176 T 12-10-2018 HW35_01600 a701729b05f9221051c711250d5b4b26 156 PIRSF PIRSF029256 2 156 1.3E-61 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 HW35_01600 a701729b05f9221051c711250d5b4b26 156 Pfam PF00588 SpoU rRNA Methylase family 3 144 5.4E-31 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HW35_01600 a701729b05f9221051c711250d5b4b26 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 153 32.356 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 HW35_01600 a701729b05f9221051c711250d5b4b26 156 SUPERFAMILY SSF75217 3 154 1.24E-37 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases HW35_01600 a701729b05f9221051c711250d5b4b26 156 Gene3D G3DSA:3.40.1280.10 1 156 4.5E-62 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HW35_01600 a701729b05f9221051c711250d5b4b26 156 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 2 155 8.1E-59 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 HW35_07775 9ed58abbfc4f78d75c490025790ca459 372 Gene3D G3DSA:1.10.10.10 8 60 2.6E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_07775 9ed58abbfc4f78d75c490025790ca459 372 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 52 1.3E-10 T 12-10-2018 HW35_07775 9ed58abbfc4f78d75c490025790ca459 372 SMART SM00419 17 63 0.0023 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_07775 9ed58abbfc4f78d75c490025790ca459 372 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 312 325 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HW35_07775 9ed58abbfc4f78d75c490025790ca459 372 Pfam PF00294 pfkB family carbohydrate kinase 67 352 1.2E-43 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB HW35_07775 9ed58abbfc4f78d75c490025790ca459 372 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 100 124 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HW35_07775 9ed58abbfc4f78d75c490025790ca459 372 SUPERFAMILY SSF46785 7 62 2.02E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_07775 9ed58abbfc4f78d75c490025790ca459 372 Gene3D G3DSA:3.40.1190.20 63 372 4.9E-76 T 12-10-2018 IPR029056 Ribokinase-like HW35_07775 9ed58abbfc4f78d75c490025790ca459 372 SUPERFAMILY SSF53613 67 360 2.96E-53 T 12-10-2018 IPR029056 Ribokinase-like HW35_09950 00e39f5dedb2e75c364a639bce0e9305 208 Gene3D G3DSA:3.30.30.80 1 56 6.2E-20 T 12-10-2018 IPR038247 Jag, N-terminal domain superfamily HW35_09950 00e39f5dedb2e75c364a639bce0e9305 208 Pfam PF01424 R3H domain 144 203 1.4E-15 T 12-10-2018 IPR001374 R3H domain GO:0003676 HW35_09950 00e39f5dedb2e75c364a639bce0e9305 208 SMART SM01245 5 57 1.0E-23 T 12-10-2018 IPR032782 Jag, N-terminal HW35_09950 00e39f5dedb2e75c364a639bce0e9305 208 Pfam PF13083 KH domain 65 128 4.6E-15 T 12-10-2018 HW35_09950 00e39f5dedb2e75c364a639bce0e9305 208 Pfam PF14804 Jag N-terminus 7 55 5.0E-21 T 12-10-2018 IPR032782 Jag, N-terminal HW35_09950 00e39f5dedb2e75c364a639bce0e9305 208 Gene3D G3DSA:3.30.1370.50 141 208 1.6E-27 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 HW35_09950 00e39f5dedb2e75c364a639bce0e9305 208 SUPERFAMILY SSF82708 146 205 5.49E-10 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 HW35_09950 00e39f5dedb2e75c364a639bce0e9305 208 SMART SM00393 126 205 7.4E-22 T 12-10-2018 IPR001374 R3H domain GO:0003676 HW35_09950 00e39f5dedb2e75c364a639bce0e9305 208 Gene3D G3DSA:3.30.300.20 59 140 2.1E-25 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta HW35_04410 d3e4115a349766586df5c812dbf2010b 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 4.4E-24 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 SUPERFAMILY SSF56645 1 242 5.76E-82 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 PIRSF PIRSF016578 3 111 1.2E-7 T 12-10-2018 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 PIRSF PIRSF016578 127 378 6.7E-20 T 12-10-2018 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.9E-37 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 3.0E-55 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 Gene3D G3DSA:2.40.110.10 121 233 2.1E-37 T 12-10-2018 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 Gene3D G3DSA:1.10.540.10 1 119 1.0E-44 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 SUPERFAMILY SSF47203 228 377 2.69E-62 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HW35_04410 d3e4115a349766586df5c812dbf2010b 380 Gene3D G3DSA:1.20.140.10 234 379 2.0E-59 T 12-10-2018 HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 Gene3D G3DSA:1.10.940.10 3 145 2.9E-40 T 12-10-2018 IPR035926 NusB-like superfamily HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 431 448 1.7E-32 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 377 393 1.7E-32 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 230 244 1.7E-32 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 259 269 1.7E-32 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 327 339 1.7E-32 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 SUPERFAMILY SSF48013 7 133 9.16E-37 T 12-10-2018 IPR035926 NusB-like superfamily HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 Pfam PF01029 NusB family 8 131 8.4E-31 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 326 337 - T 12-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 SUPERFAMILY SSF53335 142 449 4.18E-75 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 10 449 2.6E-157 T 12-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 Gene3D G3DSA:3.40.50.150 148 448 8.0E-85 T 12-10-2018 HW35_16560 c5c4142b422a48207f2c177fbd284e97 450 Pfam PF01189 16S rRNA methyltransferase RsmB/F 249 447 8.2E-63 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 HW35_03010 4daf484f79c11042228ab92e278ef5cd 189 Gene3D G3DSA:1.20.120.1630 2 187 1.7E-21 T 12-10-2018 HW35_03010 4daf484f79c11042228ab92e278ef5cd 189 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 78 168 1.2E-28 T 12-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 HW35_04635 3bc7f15a1dfa5063f331cfcdee10f480 188 TIGRFAM TIGR00277 HDIG: HDIG domain 16 110 3.5E-9 T 12-10-2018 IPR006675 HDIG domain HW35_04635 3bc7f15a1dfa5063f331cfcdee10f480 188 SMART SM00471 14 141 1.7E-12 T 12-10-2018 IPR003607 HD/PDEase domain HW35_04635 3bc7f15a1dfa5063f331cfcdee10f480 188 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 180 1.0E-68 T 12-10-2018 IPR005249 Conserved hypothetical protein CHP00488 HW35_04635 3bc7f15a1dfa5063f331cfcdee10f480 188 SUPERFAMILY SSF109604 4 179 1.68E-38 T 12-10-2018 HW35_04635 3bc7f15a1dfa5063f331cfcdee10f480 188 Pfam PF01966 HD domain 18 130 8.8E-18 T 12-10-2018 IPR006674 HD domain HW35_04635 3bc7f15a1dfa5063f331cfcdee10f480 188 Gene3D G3DSA:1.10.3210.10 1 186 1.2E-63 T 12-10-2018 HW35_09205 94a19b986db1e321e60034a125fca690 68 SUPERFAMILY SSF143800 1 65 1.77E-26 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09205 94a19b986db1e321e60034a125fca690 68 PRINTS PR01249 Ribosomal protein L31 signature 2 19 6.0E-23 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_09205 94a19b986db1e321e60034a125fca690 68 PRINTS PR01249 Ribosomal protein L31 signature 30 45 6.0E-23 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_09205 94a19b986db1e321e60034a125fca690 68 PRINTS PR01249 Ribosomal protein L31 signature 45 63 6.0E-23 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_09205 94a19b986db1e321e60034a125fca690 68 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 67 29.359 T 12-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_09205 94a19b986db1e321e60034a125fca690 68 Pfam PF01197 Ribosomal protein L31 1 64 8.1E-32 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_09205 94a19b986db1e321e60034a125fca690 68 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 1.6E-30 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_09205 94a19b986db1e321e60034a125fca690 68 Gene3D G3DSA:2.30.170.50 1 68 4.2E-32 T 12-10-2018 HW35_09205 94a19b986db1e321e60034a125fca690 68 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_17295 6b40f60c1c5d3a0d54a4995787c1d52e 417 Pfam PF00772 DnaB-like helicase N terminal domain 5 90 4.1E-5 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HW35_17295 6b40f60c1c5d3a0d54a4995787c1d52e 417 SUPERFAMILY SSF52540 154 404 2.34E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17295 6b40f60c1c5d3a0d54a4995787c1d52e 417 Gene3D G3DSA:3.40.50.300 130 416 1.7E-87 T 12-10-2018 HW35_17295 6b40f60c1c5d3a0d54a4995787c1d52e 417 SUPERFAMILY SSF48024 5 97 1.29E-5 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 HW35_17295 6b40f60c1c5d3a0d54a4995787c1d52e 417 Gene3D G3DSA:1.10.860.10 2 129 2.5E-16 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal HW35_17295 6b40f60c1c5d3a0d54a4995787c1d52e 417 Pfam PF03796 DnaB-like helicase C terminal domain 155 406 4.7E-75 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 Gene3D G3DSA:3.50.50.60 236 380 1.7E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 PRINTS PR00419 Adrenodoxin reductase family signature 202 212 1.3E-17 T 12-10-2018 HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 PRINTS PR00419 Adrenodoxin reductase family signature 270 284 1.3E-17 T 12-10-2018 HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 PRINTS PR00419 Adrenodoxin reductase family signature 137 159 1.3E-17 T 12-10-2018 HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 PRINTS PR00419 Adrenodoxin reductase family signature 160 173 1.3E-17 T 12-10-2018 HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 137 437 2.8E-38 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 Gene3D G3DSA:3.50.50.60 131 217 7.6E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 15 123 9.1E-41 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 SUPERFAMILY SSF46548 5 146 8.37E-34 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 Gene3D G3DSA:1.10.1060.10 2 130 3.3E-44 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HW35_01175 7c2e9171e07ac1da56d8210ff29bb2c9 456 SUPERFAMILY SSF51971 134 381 2.71E-63 T 12-10-2018 HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 SUPERFAMILY SSF69075 317 420 1.7E-15 T 12-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 Gene3D G3DSA:3.40.50.720 161 313 7.1E-48 T 12-10-2018 HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 1.3E-46 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 SUPERFAMILY SSF69742 1 158 8.5E-48 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 Gene3D G3DSA:3.30.460.30 1 158 2.7E-56 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 PIRSF PIRSF000445 1 435 2.6E-157 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 SUPERFAMILY SSF51735 162 315 2.29E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 4.3E-158 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 5.3E-47 T 12-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 323 419 6.0E-20 T 12-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HW35_05240 0da797cba0fc2889cfbd0562e2de8518 447 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 30.005 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 9 471 1.2E-244 T 12-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 Gene3D G3DSA:1.10.40.30 411 462 5.2E-20 T 12-10-2018 HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 4.0E-32 T 12-10-2018 IPR000362 Fumarate lyase family HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 4.0E-32 T 12-10-2018 IPR000362 Fumarate lyase family HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 4.0E-32 T 12-10-2018 IPR000362 Fumarate lyase family HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 4.0E-32 T 12-10-2018 IPR000362 Fumarate lyase family HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 Pfam PF00206 Lyase 16 345 3.5E-115 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 1.0E-6 T 12-10-2018 HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 1.0E-6 T 12-10-2018 HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 Pfam PF10415 Fumarase C C-terminus 412 464 1.7E-18 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 Gene3D G3DSA:1.20.200.10 143 410 5.0E-117 T 12-10-2018 HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 SUPERFAMILY SSF48557 8 465 6.91E-152 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 HW35_13060 fd98c6c7adc5abeb2914a8406208816b 476 Gene3D G3DSA:1.10.275.10 9 142 6.5E-59 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 Gene3D G3DSA:3.40.50.261 240 386 1.4E-58 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 Pfam PF08442 ATP-grasp domain 2 203 3.8E-84 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 Gene3D G3DSA:3.30.1490.20 21 104 1.1E-98 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 Pfam PF00549 CoA-ligase 262 381 1.0E-26 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 PIRSF PIRSF001554 1 386 4.6E-159 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 SUPERFAMILY SSF56059 1 238 4.47E-87 T 12-10-2018 HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.4E-168 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 45.617 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 Gene3D G3DSA:3.30.470.20 1 234 1.1E-98 T 12-10-2018 HW35_16725 9588f6f8ac2f73417cf6fc278823c331 386 SUPERFAMILY SSF52210 239 386 3.79E-56 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HW35_10640 21d44bac17c2921deb418d6297fdac4e 60 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 6 58 2.2E-19 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HW35_10640 21d44bac17c2921deb418d6297fdac4e 60 Hamap MF_00422 Protein translocase subunit SecE [secE]. 2 57 12.475 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HW35_10640 21d44bac17c2921deb418d6297fdac4e 60 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 7 35 - T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HW35_10640 21d44bac17c2921deb418d6297fdac4e 60 Gene3D G3DSA:1.20.5.1030 1 58 1.7E-18 T 12-10-2018 IPR038379 SecE superfamily HW35_10640 21d44bac17c2921deb418d6297fdac4e 60 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 4 59 2.3E-21 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 HW35_09745 d9ee25b574b8f14ccaa4118f530a9677 419 Pfam PF08388 Group II intron, maturase-specific domain 288 360 6.0E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_09745 d9ee25b574b8f14ccaa4118f530a9677 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_09745 d9ee25b574b8f14ccaa4118f530a9677 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_09745 d9ee25b574b8f14ccaa4118f530a9677 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_09745 d9ee25b574b8f14ccaa4118f530a9677 419 SUPERFAMILY SSF56672 16 356 3.5E-63 T 12-10-2018 HW35_09745 d9ee25b574b8f14ccaa4118f530a9677 419 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 8.7E-48 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_09745 d9ee25b574b8f14ccaa4118f530a9677 419 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 7.6E-134 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 93 116 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 407 426 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 120 144 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 379 397 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 223 242 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 320 335 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 174 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 457 478 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 46 71 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 344 365 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 274 295 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 194 212 9.8E-95 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 276 330 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 4 643 0.0 T 12-10-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 SUPERFAMILY SSF81442 44 555 5.36E-172 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 55 500 2.2E-139 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01960 2759d0a9cea51a7d791d06f0b4ca4f90 648 Gene3D G3DSA:1.20.210.10 16 561 1.7E-194 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_15575 59b772a3b20e6d02582bb98f6cd43593 286 ProSitePatterns PS00770 Aminotransferases class-IV signature. 178 207 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 HW35_15575 59b772a3b20e6d02582bb98f6cd43593 286 Gene3D G3DSA:3.20.10.10 124 274 2.7E-47 T 12-10-2018 HW35_15575 59b772a3b20e6d02582bb98f6cd43593 286 Gene3D G3DSA:3.30.470.10 1 123 1.6E-36 T 12-10-2018 HW35_15575 59b772a3b20e6d02582bb98f6cd43593 286 Pfam PF01063 Amino-transferase class IV 29 251 4.5E-59 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 HW35_15575 59b772a3b20e6d02582bb98f6cd43593 286 SUPERFAMILY SSF56752 1 274 1.7E-74 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 HW35_17540 d88c2225a56c87f47b4fecac51e091bf 66 Gene3D G3DSA:2.40.50.140 1 66 5.5E-30 T 12-10-2018 HW35_17540 d88c2225a56c87f47b4fecac51e091bf 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site HW35_17540 d88c2225a56c87f47b4fecac51e091bf 66 PIRSF PIRSF002599 1 66 4.3E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 HW35_17540 d88c2225a56c87f47b4fecac51e091bf 66 PRINTS PR00050 Cold shock protein signature 24 33 4.2E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_17540 d88c2225a56c87f47b4fecac51e091bf 66 PRINTS PR00050 Cold shock protein signature 39 57 4.2E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_17540 d88c2225a56c87f47b4fecac51e091bf 66 PRINTS PR00050 Cold shock protein signature 4 19 4.2E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_17540 d88c2225a56c87f47b4fecac51e091bf 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 9.2E-31 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_17540 d88c2225a56c87f47b4fecac51e091bf 66 SMART SM00357 3 66 3.7E-31 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 HW35_17540 d88c2225a56c87f47b4fecac51e091bf 66 SUPERFAMILY SSF50249 1 64 1.7E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_00335 dd04f613f638906949d04d4f7039bee6 289 Gene3D G3DSA:1.10.443.10 108 285 4.6E-47 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 HW35_00335 dd04f613f638906949d04d4f7039bee6 289 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 4 83 6.3E-7 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HW35_00335 dd04f613f638906949d04d4f7039bee6 289 Pfam PF00589 Phage integrase family 111 279 1.4E-39 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HW35_00335 dd04f613f638906949d04d4f7039bee6 289 SUPERFAMILY SSF56349 6 286 1.18E-45 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HW35_00335 dd04f613f638906949d04d4f7039bee6 289 Gene3D G3DSA:1.10.150.130 2 88 3.7E-14 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal HW35_01485 cae49dfa8a0faf3ee924cfee095aa017 80 Gene3D G3DSA:1.10.260.40 2 75 2.9E-22 T 12-10-2018 HW35_01485 cae49dfa8a0faf3ee924cfee095aa017 80 Pfam PF12844 Helix-turn-helix domain 14 75 4.9E-18 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_01485 cae49dfa8a0faf3ee924cfee095aa017 80 SMART SM00530 16 73 2.4E-17 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_01485 cae49dfa8a0faf3ee924cfee095aa017 80 SUPERFAMILY SSF47413 10 77 8.85E-20 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_06965 17f75f41e441b7b9ce33fb8c56e838ba 336 TIGRFAM TIGR02905 spore_yutH: spore coat protein YutH 4 315 1.8E-118 T 12-10-2018 IPR014254 Spore coat protein YutH HW35_06965 17f75f41e441b7b9ce33fb8c56e838ba 336 SUPERFAMILY SSF56112 28 317 7.48E-16 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_06965 17f75f41e441b7b9ce33fb8c56e838ba 336 Gene3D G3DSA:3.90.1200.10 90 315 1.4E-24 T 12-10-2018 HW35_00805 035e0860907004ede35e4b9667e07030 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 57.508 T 12-10-2018 IPR026562 Probable transcriptional regulatory protein YeeN HW35_00805 035e0860907004ede35e4b9667e07030 239 SUPERFAMILY SSF75625 1 238 2.22E-82 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_00805 035e0860907004ede35e4b9667e07030 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 236 6.9E-73 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_00805 035e0860907004ede35e4b9667e07030 239 Pfam PF01709 Transcriptional regulator 4 235 8.7E-83 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_00805 035e0860907004ede35e4b9667e07030 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.804 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_00805 035e0860907004ede35e4b9667e07030 239 Gene3D G3DSA:1.10.10.200 2 79 6.2E-25 T 12-10-2018 IPR017856 Integrase-like, N-terminal HW35_00805 035e0860907004ede35e4b9667e07030 239 Gene3D G3DSA:3.30.70.980 83 234 1.7E-45 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_00805 035e0860907004ede35e4b9667e07030 239 Gene3D G3DSA:3.30.70.980 131 201 1.7E-45 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_09985 587a8a1e1ec431b0ad7526d0a86f0c05 372 Gene3D G3DSA:3.40.50.300 6 345 2.0E-112 T 12-10-2018 HW35_09985 587a8a1e1ec431b0ad7526d0a86f0c05 372 Gene3D G3DSA:1.20.1050.90 119 311 2.0E-112 T 12-10-2018 HW35_09985 587a8a1e1ec431b0ad7526d0a86f0c05 372 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 346 2.4E-16 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal HW35_09985 587a8a1e1ec431b0ad7526d0a86f0c05 372 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 HW35_09985 587a8a1e1ec431b0ad7526d0a86f0c05 372 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 372 105.256 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 HW35_09985 587a8a1e1ec431b0ad7526d0a86f0c05 372 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 HW35_09985 587a8a1e1ec431b0ad7526d0a86f0c05 372 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 365 2.6E-136 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 HW35_09985 587a8a1e1ec431b0ad7526d0a86f0c05 372 SUPERFAMILY SSF52540 1 351 6.1E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16525 0c64aaa2e9d4da24ac8af8fe8c9d590d 87 Pfam PF04025 Domain of unknown function (DUF370) 5 77 1.8E-37 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A HW35_16525 0c64aaa2e9d4da24ac8af8fe8c9d590d 87 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 78 1.0E-33 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A HW35_16525 0c64aaa2e9d4da24ac8af8fe8c9d590d 87 Hamap MF_01503 UPF0296 protein . 3 85 29.798 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A HW35_07450 a0825423779b8f3423657359e709555d 390 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 11 384 3.5E-157 T 12-10-2018 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase HW35_07450 a0825423779b8f3423657359e709555d 390 SUPERFAMILY SSF53383 11 385 1.1E-129 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_07450 a0825423779b8f3423657359e709555d 390 Gene3D G3DSA:3.40.640.10 1 259 6.1E-110 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_07450 a0825423779b8f3423657359e709555d 390 Gene3D G3DSA:3.90.1150.10 260 388 5.1E-39 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_07450 a0825423779b8f3423657359e709555d 390 PIRSF PIRSF000390 8 388 1.1E-124 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HW35_07450 a0825423779b8f3423657359e709555d 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 18 381 5.1E-131 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HW35_05795 e2672e4617983ef7396bf303af46167c 397 Gene3D G3DSA:3.30.420.40 2 194 1.1E-76 T 12-10-2018 HW35_05795 e2672e4617983ef7396bf303af46167c 397 PRINTS PR00471 Acetate kinase family signature 172 185 4.6E-48 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 PRINTS PR00471 Acetate kinase family signature 202 223 4.6E-48 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 PRINTS PR00471 Acetate kinase family signature 299 312 4.6E-48 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 PRINTS PR00471 Acetate kinase family signature 321 337 4.6E-48 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 PRINTS PR00471 Acetate kinase family signature 375 387 4.6E-48 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 PRINTS PR00471 Acetate kinase family signature 4 15 4.6E-48 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 SUPERFAMILY SSF53067 1 194 6.09E-74 T 12-10-2018 HW35_05795 e2672e4617983ef7396bf303af46167c 397 Pfam PF00871 Acetokinase family 3 388 9.4E-172 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 SUPERFAMILY SSF53067 157 393 6.26E-95 T 12-10-2018 HW35_05795 e2672e4617983ef7396bf303af46167c 397 Gene3D G3DSA:3.30.420.40 195 397 2.0E-83 T 12-10-2018 HW35_05795 e2672e4617983ef7396bf303af46167c 397 PIRSF PIRSF000722 1 397 1.9E-154 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 198.88 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 TIGRFAM TIGR00016 ackA: acetate kinase 2 394 2.6E-178 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_05795 e2672e4617983ef7396bf303af46167c 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HW35_16975 57ec2bebac6a80f6608a3d3d7b887bed 303 Pfam PF13464 Domain of unknown function (DUF4115) 219 285 2.7E-8 T 12-10-2018 IPR025194 Domain of unknown function DUF4115 HW35_16975 57ec2bebac6a80f6608a3d3d7b887bed 303 SUPERFAMILY SSF47413 3 75 8.73E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_16975 57ec2bebac6a80f6608a3d3d7b887bed 303 SMART SM00530 7 68 1.3E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_16975 57ec2bebac6a80f6608a3d3d7b887bed 303 Pfam PF13413 Helix-turn-helix domain 7 68 1.2E-21 T 12-10-2018 HW35_16975 57ec2bebac6a80f6608a3d3d7b887bed 303 Gene3D G3DSA:1.10.260.40 1 104 8.2E-30 T 12-10-2018 HW35_07415 aeeac95a9963eef950a9009f74030659 335 SMART SM00846 3 152 2.8E-101 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07415 aeeac95a9963eef950a9009f74030659 335 SUPERFAMILY SSF55347 152 314 4.46E-75 T 12-10-2018 HW35_07415 aeeac95a9963eef950a9009f74030659 335 SUPERFAMILY SSF51735 1 180 3.34E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_07415 aeeac95a9963eef950a9009f74030659 335 Gene3D G3DSA:3.30.360.10 151 315 6.0E-163 T 12-10-2018 HW35_07415 aeeac95a9963eef950a9009f74030659 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 2.3E-73 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07415 aeeac95a9963eef950a9009f74030659 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07415 aeeac95a9963eef950a9009f74030659 335 Gene3D G3DSA:3.40.50.720 4 329 6.0E-163 T 12-10-2018 HW35_07415 aeeac95a9963eef950a9009f74030659 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 6.9E-143 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07415 aeeac95a9963eef950a9009f74030659 335 PIRSF PIRSF000149 1 334 2.5E-144 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07415 aeeac95a9963eef950a9009f74030659 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 5.5E-41 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07415 aeeac95a9963eef950a9009f74030659 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 3.7E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07415 aeeac95a9963eef950a9009f74030659 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 3.7E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07415 aeeac95a9963eef950a9009f74030659 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 3.7E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07415 aeeac95a9963eef950a9009f74030659 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 3.7E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07415 aeeac95a9963eef950a9009f74030659 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 3.7E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 SUPERFAMILY SSF51569 1 287 2.83E-104 T 12-10-2018 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 Pfam PF00701 Dihydrodipicolinate synthetase family 4 287 3.8E-111 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 Gene3D G3DSA:3.20.20.70 1 289 8.8E-115 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 8.0E-35 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 8.0E-35 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 8.0E-35 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 8.0E-35 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 SMART SM01130 3 287 7.1E-140 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 289 64.977 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 288 4.5E-115 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_16900 23d5c3c6118bfddf799a5343a9aa449c 290 PIRSF PIRSF001365 1 289 3.4E-100 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 183 205 6.7E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 351 362 6.7E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 103 117 6.7E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 225 245 6.7E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 111 124 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 Gene3D G3DSA:3.40.50.720 199 352 1.5E-142 T 12-10-2018 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 SUPERFAMILY SSF53223 17 194 1.25E-65 T 12-10-2018 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 192 423 1.1E-80 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 Gene3D G3DSA:1.10.8.1210 378 425 8.6E-19 T 12-10-2018 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 Gene3D G3DSA:1.10.8.1210 25 353 1.5E-142 T 12-10-2018 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 Gene3D G3DSA:3.40.50.10860 44 198 1.5E-142 T 12-10-2018 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 PIRSF PIRSF000185 13 425 1.8E-174 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 SUPERFAMILY SSF51735 192 424 6.31E-80 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 SMART SM00839 194 423 2.1E-96 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03475 9dc3a25b3035b2c8f3420fbeb226b7e5 425 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 47 174 1.6E-53 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Gene3D G3DSA:1.10.268.10 370 459 3.1E-220 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 6 810 25.082 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Gene3D G3DSA:3.30.1360.40 237 333 3.1E-220 T 12-10-2018 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 472 9.9E-162 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 SUPERFAMILY SSF101904 500 819 3.66E-114 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 SUPERFAMILY SSF56719 31 487 1.44E-182 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 807 5.9E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 612 655 6.0E-7 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 555 604 1.9E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 506 551 1.1E-14 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 710 756 2.3E-15 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 705 9.4E-15 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Gene3D G3DSA:3.90.199.10 33 486 3.1E-220 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 Gene3D G3DSA:2.120.10.90 498 810 5.1E-128 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 809 0.0 T 12-10-2018 HW35_10000 f984418ae6711244e1b18201c2fc6b30 823 SMART SM00434 12 465 3.4E-294 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_04110 3cf77fc2c09288087b0087549a8600f0 179 SMART SM00855 3 141 1.2E-7 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HW35_04110 3cf77fc2c09288087b0087549a8600f0 179 Gene3D G3DSA:3.40.50.1240 1 169 6.9E-32 T 12-10-2018 IPR029033 Histidine phosphatase superfamily HW35_04110 3cf77fc2c09288087b0087549a8600f0 179 SUPERFAMILY SSF53254 2 171 2.09E-32 T 12-10-2018 IPR029033 Histidine phosphatase superfamily HW35_04110 3cf77fc2c09288087b0087549a8600f0 179 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 155 6.4E-25 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HW35_06290 cfdd966da152aa470b18dad8ea933d8e 141 Pfam PF10916 Protein of unknown function (DUF2712) 30 141 8.8E-49 T 12-10-2018 IPR020208 Protein of unknown function DUF2712 HW35_06290 cfdd966da152aa470b18dad8ea933d8e 141 ProDom PD088182 YYBN 1 140 2.0E-29 T 12-10-2018 IPR020208 Protein of unknown function DUF2712 HW35_16720 0fadf7436a39f3a76173b6e62d25dd1a 261 Hamap MF_00052_B Ribonuclease HII [rnhB]. 73 251 35.879 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 HW35_16720 0fadf7436a39f3a76173b6e62d25dd1a 261 Pfam PF01351 Ribonuclease HII 75 250 6.3E-37 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain HW35_16720 0fadf7436a39f3a76173b6e62d25dd1a 261 SUPERFAMILY SSF53098 63 256 1.03E-66 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_16720 0fadf7436a39f3a76173b6e62d25dd1a 261 Gene3D G3DSA:3.30.420.10 50 261 1.7E-77 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_04875 084f1022cb8374071b02993d682365f1 589 SUPERFAMILY SSF55261 294 421 6.05E-47 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 HW35_04875 084f1022cb8374071b02993d682365f1 589 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 2 584 1.1E-263 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 HW35_04875 084f1022cb8374071b02993d682365f1 589 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 2.5E-17 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HW35_04875 084f1022cb8374071b02993d682365f1 589 Gene3D G3DSA:3.30.930.10 121 583 9.6E-200 T 12-10-2018 HW35_04875 084f1022cb8374071b02993d682365f1 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 9.5E-27 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_04875 084f1022cb8374071b02993d682365f1 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 195 207 9.5E-27 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_04875 084f1022cb8374071b02993d682365f1 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 212 225 9.5E-27 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_04875 084f1022cb8374071b02993d682365f1 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 9.5E-27 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_04875 084f1022cb8374071b02993d682365f1 589 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 559 1.4E-112 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_04875 084f1022cb8374071b02993d682365f1 589 Gene3D G3DSA:3.30.1360.30 277 421 9.6E-200 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 HW35_04875 084f1022cb8374071b02993d682365f1 589 Gene3D G3DSA:2.40.50.140 1 108 1.2E-33 T 12-10-2018 HW35_04875 084f1022cb8374071b02993d682365f1 589 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 586 35.47 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 HW35_04875 084f1022cb8374071b02993d682365f1 589 SUPERFAMILY SSF50249 4 108 1.43E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_04875 084f1022cb8374071b02993d682365f1 589 Pfam PF02938 GAD domain 313 407 4.8E-33 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 HW35_04875 084f1022cb8374071b02993d682365f1 589 SUPERFAMILY SSF55681 113 582 3.2E-111 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 SUPERFAMILY SSF81653 301 397 1.44E-31 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 Pfam PF00403 Heavy-metal-associated domain 11 69 1.3E-16 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 Pfam PF00403 Heavy-metal-associated domain 78 138 1.4E-17 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 Pfam PF00122 E1-E2 ATPase 298 478 1.5E-61 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00942 Copper-transporting ATPase 1 signature 7 32 1.4E-14 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00942 Copper-transporting ATPase 1 signature 33 56 1.4E-14 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00942 Copper-transporting ATPase 1 signature 213 238 1.4E-14 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 Gene3D G3DSA:3.40.50.1000 480 750 1.8E-97 T 12-10-2018 IPR023214 HAD superfamily HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 270 782 4.5E-96 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 212 801 2.7E-191 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 230 800 1.7E-209 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 8 71 5.1E-12 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 75 139 2.2E-12 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 Gene3D G3DSA:3.40.1110.10 510 630 1.8E-97 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 645 655 2.1E-28 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 721 733 2.1E-28 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 347 361 2.1E-28 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 698 717 2.1E-28 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 499 513 2.1E-28 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 634 2.1E-28 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 SUPERFAMILY SSF55008 3 72 3.67E-21 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 Gene3D G3DSA:2.70.150.20 290 402 9.7E-46 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00943 Copper-transporting ATPase signature 119 139 2.4E-22 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00943 Copper-transporting ATPase signature 90 104 2.4E-22 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00943 Copper-transporting ATPase signature 420 434 2.4E-22 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00943 Copper-transporting ATPase signature 732 746 2.4E-22 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00943 Copper-transporting ATPase signature 215 234 2.4E-22 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00943 Copper-transporting ATPase signature 267 286 2.4E-22 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00943 Copper-transporting ATPase signature 482 497 2.4E-22 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00943 Copper-transporting ATPase signature 675 692 2.4E-22 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 PRINTS PR00943 Copper-transporting ATPase signature 287 305 2.4E-22 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 ProSitePatterns PS01047 Heavy-metal-associated domain. 80 109 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 SUPERFAMILY SSF56784 497 798 6.09E-63 T 12-10-2018 IPR036412 HAD-like superfamily HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 SUPERFAMILY SSF81665 265 767 2.48E-13 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 ProSitePatterns PS01047 Heavy-metal-associated domain. 12 41 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 Pfam PF00702 haloacid dehalogenase-like hydrolase 495 712 9.0E-47 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 SUPERFAMILY SSF55008 74 143 6.41E-22 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 501 507 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 Gene3D G3DSA:3.30.70.100 3 72 5.9E-22 T 12-10-2018 HW35_00580 e967143ad4600dfb3df7c69e78ea9c09 805 Gene3D G3DSA:3.30.70.100 73 149 9.1E-25 T 12-10-2018 HW35_03560 9a5a1bcd13d9f3affe1271982406c429 238 SMART SM00862 156 233 2.4E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_03560 9a5a1bcd13d9f3affe1271982406c429 238 Pfam PF00072 Response regulator receiver domain 7 115 9.3E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_03560 9a5a1bcd13d9f3affe1271982406c429 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 233 4.5E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_03560 9a5a1bcd13d9f3affe1271982406c429 238 SUPERFAMILY SSF52172 4 191 1.3E-43 T 12-10-2018 IPR011006 CheY-like superfamily HW35_03560 9a5a1bcd13d9f3affe1271982406c429 238 SMART SM00448 5 115 4.9E-47 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_03560 9a5a1bcd13d9f3affe1271982406c429 238 Gene3D G3DSA:3.40.50.2300 3 128 5.9E-41 T 12-10-2018 HW35_03560 9a5a1bcd13d9f3affe1271982406c429 238 Gene3D G3DSA:1.10.10.10 136 238 1.6E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 SUPERFAMILY SSF54211 478 598 1.01E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Gene3D G3DSA:3.30.70.240 603 673 1.6E-96 T 12-10-2018 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.7E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.7E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.7E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 PRINTS PR00315 GTP-binding elongation factor signature 130 139 4.7E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.7E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Gene3D G3DSA:3.30.230.10 483 686 1.6E-96 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Pfam PF00679 Elongation factor G C-terminus 599 685 3.5E-32 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Hamap MF_00054_B Elongation factor G [fusA]. 6 690 115.119 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Pfam PF03764 Elongation factor G, domain IV 478 596 7.3E-48 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Gene3D G3DSA:3.40.50.300 1 290 1.4E-116 T 12-10-2018 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Pfam PF14492 Elongation Factor G, domain II 403 476 2.3E-35 T 12-10-2018 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Pfam PF03144 Elongation factor Tu domain 2 323 390 6.3E-16 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Gene3D G3DSA:2.40.30.10 291 404 6.0E-47 T 12-10-2018 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 SUPERFAMILY SSF50447 263 403 1.29E-36 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 SUPERFAMILY SSF54980 401 479 1.33E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 SUPERFAMILY SSF52540 6 280 6.8E-113 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 SMART SM00889 479 597 2.8E-75 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 SMART SM00838 599 686 1.8E-57 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 2.7E-71 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 2.2E-45 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 Gene3D G3DSA:3.30.70.870 405 479 2.5E-33 T 12-10-2018 HW35_10700 6b9ae275fd8587f7329c06638abe4926 693 SUPERFAMILY SSF54980 602 689 4.7E-31 T 12-10-2018 IPR035647 EF-G domain III/V-like HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 12-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 Gene3D G3DSA:3.30.590.10 108 444 3.8E-149 T 12-10-2018 HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 12-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 SMART SM01230 105 354 3.4E-143 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 Gene3D G3DSA:3.10.20.70 2 107 4.2E-46 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 2.4E-185 T 12-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 99 3.0E-34 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 SUPERFAMILY SSF54368 6 104 1.7E-36 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 3.4E-142 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 SUPERFAMILY SSF55931 106 441 8.44E-130 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 HW35_17175 74110e6f88a47368fa6db133c33d12b8 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 HW35_16010 885387a56270e2a60975b425a747894f 265 Gene3D G3DSA:3.40.190.80 144 264 2.6E-33 T 12-10-2018 HW35_16010 885387a56270e2a60975b425a747894f 265 SUPERFAMILY SSF56655 4 257 1.3E-76 T 12-10-2018 HW35_16010 885387a56270e2a60975b425a747894f 265 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 212 226 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 HW35_16010 885387a56270e2a60975b425a747894f 265 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 83 96 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site HW35_16010 885387a56270e2a60975b425a747894f 265 Pfam PF00459 Inositol monophosphatase family 4 258 1.3E-66 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 HW35_16010 885387a56270e2a60975b425a747894f 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 3.7E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 HW35_16010 885387a56270e2a60975b425a747894f 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 178 199 3.7E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 HW35_16010 885387a56270e2a60975b425a747894f 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 132 155 3.7E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 HW35_16010 885387a56270e2a60975b425a747894f 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 3.7E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 HW35_16010 885387a56270e2a60975b425a747894f 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 3.7E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 HW35_16010 885387a56270e2a60975b425a747894f 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 3.7E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 HW35_16010 885387a56270e2a60975b425a747894f 265 Gene3D G3DSA:3.30.540.10 2 143 5.6E-45 T 12-10-2018 HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 Gene3D G3DSA:2.40.30.10 661 758 2.1E-36 T 12-10-2018 HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 Gene3D G3DSA:3.40.50.300 256 430 2.2E-74 T 12-10-2018 HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 ProSitePatterns PS01176 Initiation factor 2 signature. 710 732 - T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 Pfam PF11987 Translation-initiation factor 2 545 649 2.1E-38 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 Gene3D G3DSA:1.10.10.2480 1 69 2.5E-15 T 12-10-2018 HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 Pfam PF00009 Elongation factor Tu GTP binding domain 264 419 1.2E-35 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 176 757 1.5E-283 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 Gene3D G3DSA:3.40.50.10050 553 660 6.5E-40 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 Gene3D G3DSA:2.40.30.10 431 548 6.0E-44 T 12-10-2018 HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 184 233 1.4E-14 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 52 6.9E-14 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 SUPERFAMILY SSF52540 252 432 6.85E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 SUPERFAMILY SSF50447 431 514 6.31E-28 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 SUPERFAMILY SSF50447 660 757 1.7E-34 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 261 418 1.9E-39 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 SUPERFAMILY SSF52156 538 666 4.58E-39 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily HW35_16830 8c63c73f040666e23dc700a412fcdd4c 758 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 757 17.753 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 SUPERFAMILY SSF51621 1 344 7.68E-106 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 Pfam PF00224 Pyruvate kinase, barrel domain 3 345 6.2E-159 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 Pfam PF00391 PEP-utilising enzyme, mobile domain 506 577 8.6E-21 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 SUPERFAMILY SSF50800 72 168 1.22E-26 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 SUPERFAMILY SSF52009 467 584 2.88E-29 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 474 3.9E-191 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 Gene3D G3DSA:2.40.33.10 72 168 6.4E-153 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 SUPERFAMILY SSF52935 324 475 6.28E-45 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 PRINTS PR01050 Pyruvate kinase family signature 245 269 1.6E-80 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 PRINTS PR01050 Pyruvate kinase family signature 60 76 1.6E-80 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 PRINTS PR01050 Pyruvate kinase family signature 187 201 1.6E-80 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 PRINTS PR01050 Pyruvate kinase family signature 314 330 1.6E-80 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 PRINTS PR01050 Pyruvate kinase family signature 218 244 1.6E-80 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 PRINTS PR01050 Pyruvate kinase family signature 270 294 1.6E-80 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 PRINTS PR01050 Pyruvate kinase family signature 295 313 1.6E-80 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 Gene3D G3DSA:3.40.1380.20 341 475 4.2E-46 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 Pfam PF02887 Pyruvate kinase, alpha/beta domain 359 472 7.1E-36 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 ProSitePatterns PS00110 Pyruvate kinase active site signature. 216 228 - T 12-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 Gene3D G3DSA:3.20.20.60 5 333 6.4E-153 T 12-10-2018 HW35_05685 37fd8b5ccbdaea49d103e4df4aba01e7 587 Gene3D G3DSA:3.50.30.10 476 587 1.4E-34 T 12-10-2018 HW35_13510 26f04e0092fdca16a52e3333205b31ae 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 8.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_13510 26f04e0092fdca16a52e3333205b31ae 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 8.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_13510 26f04e0092fdca16a52e3333205b31ae 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 8.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_13510 26f04e0092fdca16a52e3333205b31ae 217 SUPERFAMILY SSF52172 2 134 3.27E-31 T 12-10-2018 IPR011006 CheY-like superfamily HW35_13510 26f04e0092fdca16a52e3333205b31ae 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 5.8E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_13510 26f04e0092fdca16a52e3333205b31ae 217 SMART SM00448 2 116 1.9E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_13510 26f04e0092fdca16a52e3333205b31ae 217 Gene3D G3DSA:3.40.50.12740 2 213 1.4E-69 T 12-10-2018 HW35_13510 26f04e0092fdca16a52e3333205b31ae 217 Pfam PF00072 Response regulator receiver domain 4 117 1.0E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_13510 26f04e0092fdca16a52e3333205b31ae 217 SUPERFAMILY SSF46894 148 214 5.78E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_13510 26f04e0092fdca16a52e3333205b31ae 217 SMART SM00421 150 207 5.7E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_05655 59e95d9b42c46ffb3c5996f17e5a1976 158 Pfam PF01575 MaoC like domain 25 131 6.6E-10 T 12-10-2018 IPR002539 MaoC-like dehydratase domain HW35_05655 59e95d9b42c46ffb3c5996f17e5a1976 158 Gene3D G3DSA:3.10.129.10 10 155 2.5E-29 T 12-10-2018 HW35_05655 59e95d9b42c46ffb3c5996f17e5a1976 158 SUPERFAMILY SSF54637 14 142 4.7E-24 T 12-10-2018 IPR029069 HotDog domain superfamily HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 Gene3D G3DSA:3.60.15.10 11 444 2.5E-182 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 SUPERFAMILY SSF56281 9 426 2.29E-96 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 555 5.2E-196 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 Gene3D G3DSA:3.40.50.10710 207 357 2.5E-182 T 12-10-2018 HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 Gene3D G3DSA:3.10.20.580 451 557 1.6E-36 T 12-10-2018 HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 366 394 - T 12-10-2018 IPR001587 Ribonuclease J, conserved site HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 SMART SM00849 20 214 2.4E-31 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 365 407 1.9E-10 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 Pfam PF00753 Metallo-beta-lactamase superfamily 20 166 3.8E-17 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 PIRSF PIRSF004803 1 557 1.1E-230 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HW35_12250 a95ab2b56ff47a63bd4b7c31ba27ab71 557 Hamap MF_01491 Ribonuclease J [rnj]. 3 557 45.621 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HW35_14565 f843cff1e6d3b634324c141054a31a47 432 Pfam PF00665 Integrase core domain 270 385 2.9E-21 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_14565 f843cff1e6d3b634324c141054a31a47 432 Gene3D G3DSA:3.30.420.10 264 429 8.7E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_14565 f843cff1e6d3b634324c141054a31a47 432 Pfam PF13276 HTH-like domain 185 240 3.5E-12 T 12-10-2018 IPR025948 HTH-like domain HW35_14565 f843cff1e6d3b634324c141054a31a47 432 SUPERFAMILY SSF53098 262 427 2.58E-28 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_04840 3ad48f86e5e769d4019205a646669d54 305 SUPERFAMILY SSF53822 32 305 3.05E-88 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_04840 3ad48f86e5e769d4019205a646669d54 305 Gene3D G3DSA:3.40.50.2300 44 290 1.2E-89 T 12-10-2018 HW35_04840 3ad48f86e5e769d4019205a646669d54 305 Pfam PF13407 Periplasmic binding protein domain 41 290 2.5E-63 T 12-10-2018 IPR025997 Periplasmic binding protein HW35_04840 3ad48f86e5e769d4019205a646669d54 305 Gene3D G3DSA:3.40.50.2300 138 271 1.2E-89 T 12-10-2018 HW35_03030 aa45d4100c738e1d759a0f044e17d102 552 Gene3D G3DSA:1.20.210.10 4 552 1.8E-135 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_03030 aa45d4100c738e1d759a0f044e17d102 552 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 222 276 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_03030 aa45d4100c738e1d759a0f044e17d102 552 PRINTS PR01165 Cytochrome c oxidase subunit I signature 422 443 3.8E-12 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_03030 aa45d4100c738e1d759a0f044e17d102 552 PRINTS PR01165 Cytochrome c oxidase subunit I signature 122 134 3.8E-12 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_03030 aa45d4100c738e1d759a0f044e17d102 552 PRINTS PR01165 Cytochrome c oxidase subunit I signature 220 241 3.8E-12 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_03030 aa45d4100c738e1d759a0f044e17d102 552 PRINTS PR01165 Cytochrome c oxidase subunit I signature 291 312 3.8E-12 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_03030 aa45d4100c738e1d759a0f044e17d102 552 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 18 471 6.6E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_03030 aa45d4100c738e1d759a0f044e17d102 552 SUPERFAMILY SSF81442 16 545 3.4E-116 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_07235 30286627ca0fff48d7e6733c18ed27b9 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_07235 30286627ca0fff48d7e6733c18ed27b9 244 SMART SM00382 26 217 9.1E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_07235 30286627ca0fff48d7e6733c18ed27b9 244 PIRSF PIRSF039085 1 244 1.5E-118 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HW35_07235 30286627ca0fff48d7e6733c18ed27b9 244 Pfam PF00005 ABC transporter 17 169 1.8E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_07235 30286627ca0fff48d7e6733c18ed27b9 244 SUPERFAMILY SSF52540 1 239 4.34E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07235 30286627ca0fff48d7e6733c18ed27b9 244 Gene3D G3DSA:3.40.50.300 1 243 2.7E-77 T 12-10-2018 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 Pfam PF00108 Thiolase, N-terminal domain 5 263 2.1E-95 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 Gene3D G3DSA:3.40.47.10 5 276 5.3E-143 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 PIRSF PIRSF000429 1 394 9.1E-121 T 12-10-2018 IPR002155 Thiolase GO:0016747 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 1.2E-137 T 12-10-2018 IPR002155 Thiolase GO:0016747 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 SUPERFAMILY SSF53901 4 267 2.13E-81 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 SUPERFAMILY SSF53901 273 392 8.42E-37 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 Pfam PF02803 Thiolase, C-terminal domain 271 391 3.2E-43 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 HW35_09285 93901ab20aa0ab0f4df656503ee78665 395 Gene3D G3DSA:3.40.47.10 126 390 5.3E-143 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_03515 43feaf9919bf2f72be66fe20085a4142 500 SUPERFAMILY SSF52540 56 338 1.7E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03515 43feaf9919bf2f72be66fe20085a4142 500 Gene3D G3DSA:3.40.50.300 1 196 3.7E-68 T 12-10-2018 HW35_03515 43feaf9919bf2f72be66fe20085a4142 500 Pfam PF00271 Helicase conserved C-terminal domain 216 322 4.7E-18 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_03515 43feaf9919bf2f72be66fe20085a4142 500 Pfam PF00270 DEAD/DEAH box helicase 19 178 5.6E-22 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HW35_03515 43feaf9919bf2f72be66fe20085a4142 500 SMART SM00490 241 323 3.8E-25 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_03515 43feaf9919bf2f72be66fe20085a4142 500 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 130 139 - T 12-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site HW35_03515 43feaf9919bf2f72be66fe20085a4142 500 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 339 1.4E-108 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 HW35_03515 43feaf9919bf2f72be66fe20085a4142 500 SMART SM00487 12 209 1.4E-29 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_17070 9d67092c20fe7918b7e5960f9b417c6e 312 Gene3D G3DSA:3.10.180.10 7 302 7.7E-122 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_17070 9d67092c20fe7918b7e5960f9b417c6e 312 SUPERFAMILY SSF54593 4 282 1.24E-46 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_17070 9d67092c20fe7918b7e5960f9b417c6e 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 266 1.5E-35 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HW35_17070 9d67092c20fe7918b7e5960f9b417c6e 312 Gene3D G3DSA:3.10.180.10 67 210 7.7E-122 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_08440 c7bda2634ee10001ec6dda5fc20c9c3e 689 Gene3D G3DSA:1.10.287.950 387 688 1.7E-61 T 12-10-2018 HW35_08440 c7bda2634ee10001ec6dda5fc20c9c3e 689 Pfam PF02743 Cache domain 53 294 1.0E-18 T 12-10-2018 IPR033479 Double Cache domain 1 HW35_08440 c7bda2634ee10001ec6dda5fc20c9c3e 689 Gene3D G3DSA:1.20.1480.50 298 386 2.8E-8 T 12-10-2018 HW35_08440 c7bda2634ee10001ec6dda5fc20c9c3e 689 Gene3D G3DSA:3.30.450.20 40 187 5.1E-13 T 12-10-2018 HW35_08440 c7bda2634ee10001ec6dda5fc20c9c3e 689 SMART SM00304 332 384 2.3E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_08440 c7bda2634ee10001ec6dda5fc20c9c3e 689 SUPERFAMILY SSF58104 352 687 1.96E-65 T 12-10-2018 HW35_08440 c7bda2634ee10001ec6dda5fc20c9c3e 689 SMART SM00283 413 688 1.3E-58 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HW35_08440 c7bda2634ee10001ec6dda5fc20c9c3e 689 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 482 626 1.2E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HW35_09580 f33480cac1b8890d92ad8895ebe7369d 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_09580 f33480cac1b8890d92ad8895ebe7369d 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_09580 f33480cac1b8890d92ad8895ebe7369d 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_09580 f33480cac1b8890d92ad8895ebe7369d 301 Gene3D G3DSA:1.10.10.10 1 84 1.4E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_09580 f33480cac1b8890d92ad8895ebe7369d 301 Gene3D G3DSA:3.40.190.290 90 296 7.0E-48 T 12-10-2018 HW35_09580 f33480cac1b8890d92ad8895ebe7369d 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.4E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_09580 f33480cac1b8890d92ad8895ebe7369d 301 SUPERFAMILY SSF46785 1 84 2.5E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_09580 f33480cac1b8890d92ad8895ebe7369d 301 Pfam PF03466 LysR substrate binding domain 89 291 4.4E-43 T 12-10-2018 IPR005119 LysR, substrate-binding HW35_09580 f33480cac1b8890d92ad8895ebe7369d 301 SUPERFAMILY SSF53850 88 294 6.05E-40 T 12-10-2018 HW35_15690 93f58dc7fdd9ba8c389c8b2a949e7568 224 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 180 5.4E-37 T 12-10-2018 HW35_15690 93f58dc7fdd9ba8c389c8b2a949e7568 224 Gene3D G3DSA:3.90.1470.20 15 134 9.4E-66 T 12-10-2018 HW35_15690 93f58dc7fdd9ba8c389c8b2a949e7568 224 Gene3D G3DSA:3.40.50.1000 6 209 9.4E-66 T 12-10-2018 IPR023214 HAD superfamily HW35_15690 93f58dc7fdd9ba8c389c8b2a949e7568 224 SUPERFAMILY SSF56784 2 217 3.41E-51 T 12-10-2018 IPR036412 HAD-like superfamily HW35_15690 93f58dc7fdd9ba8c389c8b2a949e7568 224 TIGRFAM TIGR03333 salvage_mtnX: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 5 219 1.6E-96 T 12-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 HW35_15690 93f58dc7fdd9ba8c389c8b2a949e7568 224 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 2 217 46.551 T 12-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 HW35_15690 93f58dc7fdd9ba8c389c8b2a949e7568 224 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 3 187 1.2E-51 T 12-10-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 HW35_15690 93f58dc7fdd9ba8c389c8b2a949e7568 224 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 178 3.8E-20 T 12-10-2018 HW35_11345 f2c0a64e835aff9087842a39d5cfd9c4 155 SUPERFAMILY SSF109854 3 149 4.21E-20 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes HW35_11345 f2c0a64e835aff9087842a39d5cfd9c4 155 Gene3D G3DSA:1.20.120.450 2 149 4.0E-13 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes HW35_11345 f2c0a64e835aff9087842a39d5cfd9c4 155 Pfam PF12867 DinB superfamily 9 142 8.7E-16 T 12-10-2018 IPR024775 DinB-like domain HW35_14165 cba002936555ea948b9d387db8e32750 458 Gene3D G3DSA:1.10.275.10 26 230 1.0E-195 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal HW35_14165 cba002936555ea948b9d387db8e32750 458 TIGRFAM TIGR00838 argH: argininosuccinate lyase 4 456 1.1E-203 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HW35_14165 cba002936555ea948b9d387db8e32750 458 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 HW35_14165 cba002936555ea948b9d387db8e32750 458 SUPERFAMILY SSF48557 4 456 3.93E-156 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 HW35_14165 cba002936555ea948b9d387db8e32750 458 Gene3D G3DSA:1.20.200.10 120 449 1.0E-195 T 12-10-2018 HW35_14165 cba002936555ea948b9d387db8e32750 458 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 454 45.045 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HW35_14165 cba002936555ea948b9d387db8e32750 458 Pfam PF00206 Lyase 7 301 1.6E-76 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal HW35_14165 cba002936555ea948b9d387db8e32750 458 Gene3D G3DSA:1.10.40.30 361 433 1.0E-195 T 12-10-2018 HW35_14165 cba002936555ea948b9d387db8e32750 458 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 5.1E-68 T 12-10-2018 HW35_14165 cba002936555ea948b9d387db8e32750 458 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 5.1E-68 T 12-10-2018 HW35_14165 cba002936555ea948b9d387db8e32750 458 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 5.1E-68 T 12-10-2018 HW35_14165 cba002936555ea948b9d387db8e32750 458 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 5.1E-68 T 12-10-2018 HW35_14165 cba002936555ea948b9d387db8e32750 458 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 5.1E-68 T 12-10-2018 HW35_14165 cba002936555ea948b9d387db8e32750 458 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 5.1E-68 T 12-10-2018 HW35_14165 cba002936555ea948b9d387db8e32750 458 Pfam PF14698 Argininosuccinate lyase C-terminal 364 432 9.0E-25 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HW35_14165 cba002936555ea948b9d387db8e32750 458 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 3.5E-28 T 12-10-2018 IPR000362 Fumarate lyase family HW35_14165 cba002936555ea948b9d387db8e32750 458 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 3.5E-28 T 12-10-2018 IPR000362 Fumarate lyase family HW35_14165 cba002936555ea948b9d387db8e32750 458 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 3.5E-28 T 12-10-2018 IPR000362 Fumarate lyase family HW35_14165 cba002936555ea948b9d387db8e32750 458 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 3.5E-28 T 12-10-2018 IPR000362 Fumarate lyase family HW35_03330 0cd60ae10f91c3db8a5605bdb8d68f93 134 PIRSF PIRSF005965 1 124 1.7E-50 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HW35_03330 0cd60ae10f91c3db8a5605bdb8d68f93 134 SUPERFAMILY SSF55298 1 119 2.9E-48 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 HW35_03330 0cd60ae10f91c3db8a5605bdb8d68f93 134 Gene3D G3DSA:3.30.1330.40 1 124 1.1E-50 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 HW35_03330 0cd60ae10f91c3db8a5605bdb8d68f93 134 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 2 118 1.5E-49 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HW35_03330 0cd60ae10f91c3db8a5605bdb8d68f93 134 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 8 119 8.0E-35 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HW35_03330 0cd60ae10f91c3db8a5605bdb8d68f93 134 Pfam PF07736 Chorismate mutase type I 2 118 1.0E-48 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HW35_13655 b0050bc27e820d575cb837669bad1ef0 505 Gene3D G3DSA:1.10.275.10 1 195 1.5E-67 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal HW35_13655 b0050bc27e820d575cb837669bad1ef0 505 Gene3D G3DSA:1.20.200.10 196 500 1.7E-124 T 12-10-2018 HW35_13655 b0050bc27e820d575cb837669bad1ef0 505 SUPERFAMILY SSF48557 1 495 4.47E-194 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 HW35_13655 b0050bc27e820d575cb837669bad1ef0 505 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 137 153 - T 12-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 HW35_13655 b0050bc27e820d575cb837669bad1ef0 505 Pfam PF00221 Aromatic amino acid lyase 9 466 3.6E-194 T 12-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 HW35_13655 b0050bc27e820d575cb837669bad1ef0 505 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 494 1.1E-218 T 12-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_13655 b0050bc27e820d575cb837669bad1ef0 505 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 1 500 45.176 T 12-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_02510 1619a7f23e28b54f42f118125836a1ae 741 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 3 741 0.0 T 12-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 HW35_02510 1619a7f23e28b54f42f118125836a1ae 741 Pfam PF02901 Pyruvate formate lyase-like 19 600 1.5E-210 T 12-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 HW35_02510 1619a7f23e28b54f42f118125836a1ae 741 PIRSF PIRSF000379 1 741 0.0 T 12-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 HW35_02510 1619a7f23e28b54f42f118125836a1ae 741 Gene3D G3DSA:3.20.70.20 1 741 0.0 T 12-10-2018 HW35_02510 1619a7f23e28b54f42f118125836a1ae 741 Pfam PF01228 Glycine radical 616 722 2.5E-43 T 12-10-2018 IPR001150 Glycine radical domain GO:0003824 HW35_02510 1619a7f23e28b54f42f118125836a1ae 741 ProSitePatterns PS00850 Glycine radical domain signature. 711 719 - T 12-10-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site HW35_02510 1619a7f23e28b54f42f118125836a1ae 741 SUPERFAMILY SSF51998 1 740 7.02E-292 T 12-10-2018 HW35_00525 8502ebc15da2f491d9f0f54294259348 366 Pfam PF01312 FlhB HrpN YscU SpaS Family 14 354 3.2E-126 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HW35_00525 8502ebc15da2f491d9f0f54294259348 366 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 235 252 2.5E-41 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HW35_00525 8502ebc15da2f491d9f0f54294259348 366 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 309 330 2.5E-41 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HW35_00525 8502ebc15da2f491d9f0f54294259348 366 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 17 39 2.5E-41 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HW35_00525 8502ebc15da2f491d9f0f54294259348 366 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 215 233 2.5E-41 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HW35_00525 8502ebc15da2f491d9f0f54294259348 366 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 279 294 2.5E-41 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HW35_00525 8502ebc15da2f491d9f0f54294259348 366 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 15 357 1.2E-124 T 12-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 HW35_00525 8502ebc15da2f491d9f0f54294259348 366 Gene3D G3DSA:3.40.1690.10 225 365 3.5E-55 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal HW35_00525 8502ebc15da2f491d9f0f54294259348 366 SUPERFAMILY SSF160544 251 357 2.35E-39 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal HW35_08805 c264e732517f75336d580f7b5c0f7c50 199 Pfam PF00156 Phosphoribosyl transferase domain 11 152 4.5E-10 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HW35_08805 c264e732517f75336d580f7b5c0f7c50 199 Gene3D G3DSA:3.40.50.2020 4 189 2.7E-24 T 12-10-2018 HW35_08805 c264e732517f75336d580f7b5c0f7c50 199 SUPERFAMILY SSF53271 8 168 1.93E-16 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_00420 a1ee88c48b0eecbc71243d7258792dc9 482 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 475 7.1E-115 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HW35_00420 a1ee88c48b0eecbc71243d7258792dc9 482 PRINTS PR01005 Flagellar hook-associated protein signature 163 187 4.3E-8 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HW35_00420 a1ee88c48b0eecbc71243d7258792dc9 482 PRINTS PR01005 Flagellar hook-associated protein signature 130 150 4.3E-8 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HW35_00420 a1ee88c48b0eecbc71243d7258792dc9 482 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 4.3E-8 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HW35_00420 a1ee88c48b0eecbc71243d7258792dc9 482 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 422 475 1.1E-13 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HW35_00420 a1ee88c48b0eecbc71243d7258792dc9 482 SUPERFAMILY SSF64518 172 475 1.96E-24 T 12-10-2018 HW35_00420 a1ee88c48b0eecbc71243d7258792dc9 482 Pfam PF00460 Flagella basal body rod protein 8 38 1.5E-7 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HW35_13485 523ba113b611c16f56026359c6795e47 174 Gene3D G3DSA:2.102.10.10 62 173 2.3E-31 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 HW35_13485 523ba113b611c16f56026359c6795e47 174 SUPERFAMILY SSF50022 25 166 7.73E-31 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 HW35_13485 523ba113b611c16f56026359c6795e47 174 Pfam PF00355 Rieske [2Fe-2S] domain 93 154 5.2E-13 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 HW35_02540 f40035e4e576e5a30414ed465d2a7caf 261 Gene3D G3DSA:3.20.20.70 1 261 6.4E-89 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_02540 f40035e4e576e5a30414ed465d2a7caf 261 Pfam PF00290 Tryptophan synthase alpha chain 8 258 4.3E-82 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HW35_02540 f40035e4e576e5a30414ed465d2a7caf 261 SUPERFAMILY SSF51366 1 257 4.05E-84 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HW35_02540 f40035e4e576e5a30414ed465d2a7caf 261 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 260 32.568 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HW35_02540 f40035e4e576e5a30414ed465d2a7caf 261 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HW35_02540 f40035e4e576e5a30414ed465d2a7caf 261 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 260 4.3E-75 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Gene3D G3DSA:1.10.40.90 363 405 1.3E-23 T 12-10-2018 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1181 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 SMART SM00663 224 503 2.4E-186 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 759 9.2E-15 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 984 2.8E-52 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Pfam PF04998 RNA polymerase Rpb1, domain 5 996 1129 2.6E-13 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 384 2.3E-9 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 379 474 2.2E-29 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 6.7E-89 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Gene3D G3DSA:1.10.132.30 660 794 6.2E-60 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 7.8E-37 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Gene3D G3DSA:1.10.1790.20 950 1128 3.5E-66 T 12-10-2018 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Gene3D G3DSA:2.40.50.100 966 1029 3.5E-66 T 12-10-2018 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1191 18.789 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Gene3D G3DSA:1.10.150.390 1130 1191 6.6E-29 T 12-10-2018 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 SUPERFAMILY SSF64484 5 1192 0.0 T 12-10-2018 HW35_10680 5f367d091be1a32753792ae6617bd6a5 1199 Gene3D G3DSA:1.10.274.100 479 659 1.6E-48 T 12-10-2018 HW35_07135 ffa46c27614f1e3c94d3c44606da0d1f 119 SUPERFAMILY SSF52833 3 117 6.57E-39 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_07135 ffa46c27614f1e3c94d3c44606da0d1f 119 Gene3D G3DSA:3.40.30.10 1 117 1.2E-48 T 12-10-2018 HW35_07135 ffa46c27614f1e3c94d3c44606da0d1f 119 Pfam PF03960 ArsC family 6 116 1.1E-17 T 12-10-2018 IPR006660 Arsenate reductase-like HW35_07135 ffa46c27614f1e3c94d3c44606da0d1f 119 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 117 7.6E-37 T 12-10-2018 IPR006504 Transcriptional regulator Spx/MgsR HW35_04865 9452a0d38234bf077058a9dae1246960 328 SUPERFAMILY SSF53822 60 322 1.45E-67 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_04865 9452a0d38234bf077058a9dae1246960 328 Gene3D G3DSA:1.10.260.40 3 59 4.1E-25 T 12-10-2018 HW35_04865 9452a0d38234bf077058a9dae1246960 328 Pfam PF13377 Periplasmic binding protein-like domain 163 321 5.8E-31 T 12-10-2018 HW35_04865 9452a0d38234bf077058a9dae1246960 328 SUPERFAMILY SSF47413 1 59 3.94E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_04865 9452a0d38234bf077058a9dae1246960 328 Gene3D G3DSA:3.40.50.2300 153 282 1.5E-69 T 12-10-2018 HW35_04865 9452a0d38234bf077058a9dae1246960 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.1E-21 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_04865 9452a0d38234bf077058a9dae1246960 328 Gene3D G3DSA:3.40.50.2300 61 301 1.5E-69 T 12-10-2018 HW35_04865 9452a0d38234bf077058a9dae1246960 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.7E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_04865 9452a0d38234bf077058a9dae1246960 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.7E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_04865 9452a0d38234bf077058a9dae1246960 328 SMART SM00354 1 71 2.3E-38 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_04865 9452a0d38234bf077058a9dae1246960 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 HW35_09500 17abe2ec8d247b6bdfb33cd520c31b93 300 SUPERFAMILY SSF109998 124 292 6.28E-6 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily HW35_09500 17abe2ec8d247b6bdfb33cd520c31b93 300 Pfam PF13115 YtkA-like 23 98 2.6E-11 T 12-10-2018 IPR032693 YtkA-like domain HW35_01205 a5bb84a753bf3e3841720bc147a83b4d 327 PIRSF PIRSF000196 1 302 3.7E-127 T 12-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 HW35_01205 a5bb84a753bf3e3841720bc147a83b4d 327 Pfam PF01619 Proline dehydrogenase 41 291 1.9E-32 T 12-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 HW35_01205 a5bb84a753bf3e3841720bc147a83b4d 327 SUPERFAMILY SSF51730 34 304 7.85E-75 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like HW35_01205 a5bb84a753bf3e3841720bc147a83b4d 327 Gene3D G3DSA:3.20.20.530 16 300 8.9E-91 T 12-10-2018 HW35_08975 e11578fb63b4dbe0a44b1001ce38acf1 663 Pfam PF03717 Penicillin-binding Protein dimerisation domain 154 314 7.0E-38 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HW35_08975 e11578fb63b4dbe0a44b1001ce38acf1 663 Gene3D G3DSA:3.30.1390.30 175 245 1.4E-51 T 12-10-2018 HW35_08975 e11578fb63b4dbe0a44b1001ce38acf1 663 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 25 147 1.0E-25 T 12-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 HW35_08975 e11578fb63b4dbe0a44b1001ce38acf1 663 SUPERFAMILY SSF56601 334 662 6.22E-74 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_08975 e11578fb63b4dbe0a44b1001ce38acf1 663 Gene3D G3DSA:3.40.710.10 333 663 2.4E-81 T 12-10-2018 HW35_08975 e11578fb63b4dbe0a44b1001ce38acf1 663 SUPERFAMILY SSF54427 27 144 7.71E-27 T 12-10-2018 IPR032710 NTF2-like domain superfamily HW35_08975 e11578fb63b4dbe0a44b1001ce38acf1 663 Gene3D G3DSA:3.10.450.100 24 142 2.0E-23 T 12-10-2018 HW35_08975 e11578fb63b4dbe0a44b1001ce38acf1 663 SUPERFAMILY SSF56519 147 333 5.89E-41 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 HW35_08975 e11578fb63b4dbe0a44b1001ce38acf1 663 Gene3D G3DSA:3.90.1310.10 154 329 1.4E-51 T 12-10-2018 HW35_08975 e11578fb63b4dbe0a44b1001ce38acf1 663 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 659 1.2E-66 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HW35_08935 7344c2b8a1e1b89f7d2b63b137ca8e1e 130 PIRSF PIRSF002070 1 128 4.1E-34 T 12-10-2018 HW35_08935 7344c2b8a1e1b89f7d2b63b137ca8e1e 130 Gene3D G3DSA:2.40.50.140 1 112 1.8E-41 T 12-10-2018 HW35_08935 7344c2b8a1e1b89f7d2b63b137ca8e1e 130 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 112 1.3E-34 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HW35_08935 7344c2b8a1e1b89f7d2b63b137ca8e1e 130 SUPERFAMILY SSF50249 2 109 4.9E-39 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_08935 7344c2b8a1e1b89f7d2b63b137ca8e1e 130 Hamap MF_00984 Single-stranded DNA-binding protein. 2 106 31.358 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HW35_08935 7344c2b8a1e1b89f7d2b63b137ca8e1e 130 Pfam PF00436 Single-strand binding protein family 2 102 6.7E-32 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 HW35_03420 c441a461b74463d8fc5eaa50bc155a6e 352 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 330 36.495 T 12-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 HW35_03420 c441a461b74463d8fc5eaa50bc155a6e 352 Gene3D G3DSA:3.20.20.70 2 352 8.4E-122 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_03420 c441a461b74463d8fc5eaa50bc155a6e 352 Pfam PF01070 FMN-dependent dehydrogenase 166 322 3.5E-13 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 HW35_03420 c441a461b74463d8fc5eaa50bc155a6e 352 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 329 3.9E-114 T 12-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 HW35_03420 c441a461b74463d8fc5eaa50bc155a6e 352 PIRSF PIRSF003314 1 340 1.6E-118 T 12-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 HW35_03420 c441a461b74463d8fc5eaa50bc155a6e 352 SUPERFAMILY SSF51395 23 347 1.05E-78 T 12-10-2018 HW35_15790 50b872722b29cac43ab08bc2d1f77089 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 12-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site HW35_15790 50b872722b29cac43ab08bc2d1f77089 88 Gene3D G3DSA:3.30.1340.10 1 88 3.5E-36 T 12-10-2018 IPR035895 HPr-like superfamily HW35_15790 50b872722b29cac43ab08bc2d1f77089 88 SUPERFAMILY SSF55594 1 83 6.8E-28 T 12-10-2018 IPR035895 HPr-like superfamily HW35_15790 50b872722b29cac43ab08bc2d1f77089 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 6.7E-26 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like HW35_15790 50b872722b29cac43ab08bc2d1f77089 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 6.7E-26 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like HW35_15790 50b872722b29cac43ab08bc2d1f77089 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 6.7E-26 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like HW35_15790 50b872722b29cac43ab08bc2d1f77089 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site HW35_15790 50b872722b29cac43ab08bc2d1f77089 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.4E-29 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like HW35_15790 50b872722b29cac43ab08bc2d1f77089 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 1.4E-32 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like HW35_06875 4dfd3590dd1a432c5d1d13a003b286e8 126 SUPERFAMILY SSF141251 4 125 9.29E-53 T 12-10-2018 IPR038080 Kinase associated protein B superfamily HW35_06875 4dfd3590dd1a432c5d1d13a003b286e8 126 SMART SM01298 14 126 6.7E-70 T 12-10-2018 IPR014916 Kinase associated protein B HW35_06875 4dfd3590dd1a432c5d1d13a003b286e8 126 Pfam PF08810 Kinase associated protein B 14 125 7.4E-51 T 12-10-2018 IPR014916 Kinase associated protein B HW35_06875 4dfd3590dd1a432c5d1d13a003b286e8 126 Gene3D G3DSA:2.30.30.430 1 125 5.3E-53 T 12-10-2018 IPR038080 Kinase associated protein B superfamily HW35_16315 f431d0cda1b3ddb8a7bb7b410b9dbc5e 324 Pfam PF00953 Glycosyl transferase family 4 83 248 3.2E-42 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 HW35_16315 f431d0cda1b3ddb8a7bb7b410b9dbc5e 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 322 25.245 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16315 f431d0cda1b3ddb8a7bb7b410b9dbc5e 324 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 1.4E-5 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16315 f431d0cda1b3ddb8a7bb7b410b9dbc5e 324 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16315 f431d0cda1b3ddb8a7bb7b410b9dbc5e 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16315 f431d0cda1b3ddb8a7bb7b410b9dbc5e 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 323 4.5E-125 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_02910 077e419b16fa8a14a2698cb32e7782aa 216 Pfam PF01966 HD domain 28 126 1.5E-5 T 12-10-2018 IPR006674 HD domain HW35_02910 077e419b16fa8a14a2698cb32e7782aa 216 Gene3D G3DSA:1.10.472.50 1 100 1.5E-30 T 12-10-2018 HW35_02910 077e419b16fa8a14a2698cb32e7782aa 216 SUPERFAMILY SSF109604 3 213 3.14E-70 T 12-10-2018 HW35_02910 077e419b16fa8a14a2698cb32e7782aa 216 SMART SM00471 21 136 2.1E-7 T 12-10-2018 IPR003607 HD/PDEase domain HW35_02910 077e419b16fa8a14a2698cb32e7782aa 216 Gene3D G3DSA:1.20.58.1910 101 216 1.0E-47 T 12-10-2018 HW35_11410 303020b94e4469391c3e782290164032 119 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 110 2.3E-20 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 HW35_11410 303020b94e4469391c3e782290164032 119 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 116 5.5E-38 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 HW35_11410 303020b94e4469391c3e782290164032 119 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 115 2.4E-32 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 HW35_11410 303020b94e4469391c3e782290164032 119 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 114 3.0E-30 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 HW35_11410 303020b94e4469391c3e782290164032 119 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 115 25.586 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 HW35_11410 303020b94e4469391c3e782290164032 119 Gene3D G3DSA:3.90.470.20 1 118 1.9E-37 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 HW35_11410 303020b94e4469391c3e782290164032 119 SUPERFAMILY SSF56214 1 114 3.66E-33 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 HW35_07850 7e4e5da24900283b938640bcca7ca70a 420 Pfam PF08388 Group II intron, maturase-specific domain 288 360 2.8E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_07850 7e4e5da24900283b938640bcca7ca70a 420 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 6.0E-49 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_07850 7e4e5da24900283b938640bcca7ca70a 420 SUPERFAMILY SSF56672 23 346 1.08E-57 T 12-10-2018 HW35_07850 7e4e5da24900283b938640bcca7ca70a 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_07850 7e4e5da24900283b938640bcca7ca70a 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_07850 7e4e5da24900283b938640bcca7ca70a 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_07850 7e4e5da24900283b938640bcca7ca70a 420 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 6.2E-130 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 6.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 6.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 6.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 SUPERFAMILY SSF51735 7 251 1.56E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 7.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 7.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 7.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 7.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 7.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 Pfam PF00106 short chain dehydrogenase 8 204 1.2E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_13355 b93716f95066e1e42471cf5b2f38ea94 255 Gene3D G3DSA:3.40.50.720 1 254 8.6E-69 T 12-10-2018 HW35_09690 7ac746fc1b35d2dcf2a3cbebb1fa975a 148 Pfam PF04657 Putative inner membrane exporter, YdcZ 10 146 2.7E-35 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 Gene3D G3DSA:3.40.50.720 1 250 1.4E-44 T 12-10-2018 HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 SUPERFAMILY SSF51735 2 247 1.33E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 Pfam PF00106 short chain dehydrogenase 2 198 7.3E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.0E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.0E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.0E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.0E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.0E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 6.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_07215 20c608e8f2acdbb5d280dbf93ef65668 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 6.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_01420 734291e32470549e7e3cde080625b4c7 256 Pfam PF01925 Sulfite exporter TauE/SafE 7 250 6.3E-40 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HW35_12330 10fd49d46515c307e73610a66d41a73d 126 Pfam PF05099 Tellurite resistance protein TerB 66 110 1.7E-5 T 12-10-2018 IPR007791 Co-chaperone DjlA, N-terminal HW35_12330 10fd49d46515c307e73610a66d41a73d 126 SUPERFAMILY SSF158682 6 114 1.57E-15 T 12-10-2018 IPR029024 TerB-like HW35_12330 10fd49d46515c307e73610a66d41a73d 126 Gene3D G3DSA:1.10.3680.10 2 124 8.7E-15 T 12-10-2018 IPR029024 TerB-like HW35_15590 a58834761ce371b6af1746bfae0c4eab 149 SUPERFAMILY SSF55961 7 143 4.92E-18 T 12-10-2018 HW35_15590 a58834761ce371b6af1746bfae0c4eab 149 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 9 143 1.5E-9 T 12-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G HW35_15590 a58834761ce371b6af1746bfae0c4eab 149 Gene3D G3DSA:3.30.530.20 5 145 2.2E-17 T 12-10-2018 IPR023393 START-like domain superfamily HW35_05100 c2ad5c82db52fe36daf26f1899d6989f 190 SUPERFAMILY SSF52972 2 183 2.09E-61 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HW35_05100 c2ad5c82db52fe36daf26f1899d6989f 190 PIRSF PIRSF006305 1 188 2.5E-62 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 HW35_05100 c2ad5c82db52fe36daf26f1899d6989f 190 Gene3D G3DSA:3.90.950.10 1 187 1.1E-73 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HW35_05100 c2ad5c82db52fe36daf26f1899d6989f 190 Hamap MF_00528 Septum formation protein Maf [maf]. 3 188 33.111 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 HW35_05100 c2ad5c82db52fe36daf26f1899d6989f 190 Pfam PF02545 Maf-like protein 4 183 4.9E-60 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 HW35_05100 c2ad5c82db52fe36daf26f1899d6989f 190 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 182 1.1E-60 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 SUPERFAMILY SSF100934 477 581 1.57E-14 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 1.8E-289 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 Gene3D G3DSA:3.90.640.10 198 279 3.3E-156 T 12-10-2018 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 Gene3D G3DSA:2.60.34.10 347 476 4.6E-60 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 Gene3D G3DSA:1.20.1270.10 477 580 4.0E-25 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 Gene3D G3DSA:3.30.420.40 159 337 3.3E-156 T 12-10-2018 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 PRINTS PR00301 70kDa heat shock protein signature 53 61 2.6E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 PRINTS PR00301 70kDa heat shock protein signature 439 455 2.6E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.6E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.6E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 PRINTS PR00301 70kDa heat shock protein signature 304 320 2.6E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 PRINTS PR00301 70kDa heat shock protein signature 358 377 2.6E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 PRINTS PR00301 70kDa heat shock protein signature 172 182 2.6E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 PRINTS PR00301 70kDa heat shock protein signature 112 132 2.6E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 PRINTS PR00301 70kDa heat shock protein signature 335 355 2.6E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 SUPERFAMILY SSF53067 1 157 4.61E-59 T 12-10-2018 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 SUPERFAMILY SSF53067 161 351 1.43E-69 T 12-10-2018 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 Pfam PF00012 Hsp70 protein 76 573 1.2E-222 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 Pfam PF00012 Hsp70 protein 4 75 1.5E-29 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 Gene3D G3DSA:3.30.420.40 5 346 3.3E-156 T 12-10-2018 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 SUPERFAMILY SSF100920 354 510 3.4E-63 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 607 37.437 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 HW35_04540 f4e99c2afb7c96b8fbf5fc4faba78a1c 611 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 HW35_14785 6a77ad236e17f3165f47f76c2598cf68 195 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 9 191 3.0E-57 T 12-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 HW35_14785 6a77ad236e17f3165f47f76c2598cf68 195 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 11 188 5.4E-60 T 12-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 HW35_14785 6a77ad236e17f3165f47f76c2598cf68 195 Gene3D G3DSA:1.10.1760.20 5 193 1.7E-60 T 12-10-2018 HW35_10605 e3d9014346cace656218e26c87627a1b 485 SUPERFAMILY SSF52374 5 316 5.9E-115 T 12-10-2018 HW35_10605 e3d9014346cace656218e26c87627a1b 485 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_10605 e3d9014346cace656218e26c87627a1b 485 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 484 6.3E-192 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HW35_10605 e3d9014346cace656218e26c87627a1b 485 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 484 34.389 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HW35_10605 e3d9014346cace656218e26c87627a1b 485 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 1.9E-128 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 HW35_10605 e3d9014346cace656218e26c87627a1b 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 8.9E-29 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HW35_10605 e3d9014346cace656218e26c87627a1b 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 8.9E-29 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HW35_10605 e3d9014346cace656218e26c87627a1b 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 8.9E-29 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HW35_10605 e3d9014346cace656218e26c87627a1b 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 8.9E-29 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HW35_10605 e3d9014346cace656218e26c87627a1b 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 8.9E-29 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HW35_10605 e3d9014346cace656218e26c87627a1b 485 SUPERFAMILY SSF48163 298 483 1.19E-48 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HW35_10605 e3d9014346cace656218e26c87627a1b 485 Gene3D G3DSA:1.10.10.350 390 485 6.5E-33 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HW35_10605 e3d9014346cace656218e26c87627a1b 485 Gene3D G3DSA:3.40.50.620 1 332 3.2E-144 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 Pfam PF03144 Elongation factor Tu domain 2 221 291 3.3E-13 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 Gene3D G3DSA:3.40.50.300 4 200 2.6E-68 T 12-10-2018 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 SMART SM00838 397 485 9.8E-5 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 142 7.0E-24 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 Pfam PF00009 Elongation factor Tu GTP binding domain 6 197 2.1E-58 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 601 2.2E-293 T 12-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 Gene3D G3DSA:3.30.70.240 391 484 2.5E-130 T 12-10-2018 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 Gene3D G3DSA:2.40.30.10 201 301 3.4E-33 T 12-10-2018 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 SUPERFAMILY SSF50447 154 301 2.91E-33 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 Pfam PF00679 Elongation factor G C-terminus 399 478 6.8E-25 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 SUPERFAMILY SSF54980 304 389 1.87E-15 T 12-10-2018 IPR035647 EF-G domain III/V-like HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 SUPERFAMILY SSF54980 400 515 1.58E-30 T 12-10-2018 IPR035647 EF-G domain III/V-like HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 Gene3D G3DSA:3.30.70.870 308 592 2.5E-130 T 12-10-2018 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.8E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 PRINTS PR00315 GTP-binding elongation factor signature 125 134 2.8E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 PRINTS PR00315 GTP-binding elongation factor signature 89 100 2.8E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 PRINTS PR00315 GTP-binding elongation factor signature 53 61 2.8E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 PRINTS PR00315 GTP-binding elongation factor signature 73 83 2.8E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 Gene3D G3DSA:2.40.50.250 485 601 2.5E-130 T 12-10-2018 HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 SUPERFAMILY SSF52540 4 208 2.49E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16020 564abce514a8fb94c8de9639f2c22aab 613 Pfam PF14492 Elongation Factor G, domain II 330 379 1.9E-7 T 12-10-2018 HW35_11780 a868ff0ea5774510fb552dd05f416c53 515 SUPERFAMILY SSF53720 4 511 8.38E-159 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HW35_11780 a868ff0ea5774510fb552dd05f416c53 515 Pfam PF00171 Aldehyde dehydrogenase family 49 510 1.9E-160 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 HW35_11780 a868ff0ea5774510fb552dd05f416c53 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 70.326 T 12-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 HW35_11780 a868ff0ea5774510fb552dd05f416c53 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 HW35_11780 a868ff0ea5774510fb552dd05f416c53 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 515 3.6E-255 T 12-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 HW35_11780 a868ff0ea5774510fb552dd05f416c53 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 HW35_11780 a868ff0ea5774510fb552dd05f416c53 515 Gene3D G3DSA:3.40.309.10 290 480 2.1E-191 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 HW35_11780 a868ff0ea5774510fb552dd05f416c53 515 Gene3D G3DSA:3.40.605.10 9 510 2.1E-191 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_04630 0be8a143993486cab70b09ea4638c680 115 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 4 101 1.8E-36 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HW35_04630 0be8a143993486cab70b09ea4638c680 115 Gene3D G3DSA:3.30.460.10 1 105 3.3E-39 T 12-10-2018 HW35_04630 0be8a143993486cab70b09ea4638c680 115 SUPERFAMILY SSF81301 1 109 2.94E-41 T 12-10-2018 HW35_04630 0be8a143993486cab70b09ea4638c680 115 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 102 24.202 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HW35_04630 0be8a143993486cab70b09ea4638c680 115 Pfam PF02410 Ribosomal silencing factor during starvation 7 101 2.4E-26 T 12-10-2018 HW35_12835 b101a07e29901f9caa022555f494b7a0 364 Gene3D G3DSA:3.40.140.10 1 136 9.6E-44 T 12-10-2018 HW35_12835 b101a07e29901f9caa022555f494b7a0 364 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 100 1.0E-20 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain HW35_12835 b101a07e29901f9caa022555f494b7a0 364 PIRSF PIRSF006769 1 362 8.0E-129 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 HW35_12835 b101a07e29901f9caa022555f494b7a0 364 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 357 1.2E-69 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 HW35_12835 b101a07e29901f9caa022555f494b7a0 364 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 356 4.4E-122 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 HW35_12835 b101a07e29901f9caa022555f494b7a0 364 SUPERFAMILY SSF53927 4 142 3.87E-44 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 HW35_12835 b101a07e29901f9caa022555f494b7a0 364 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HW35_12835 b101a07e29901f9caa022555f494b7a0 364 Gene3D G3DSA:3.40.430.10 137 362 3.5E-74 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 HW35_12835 b101a07e29901f9caa022555f494b7a0 364 SUPERFAMILY SSF53597 146 359 3.02E-58 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 HW35_12835 b101a07e29901f9caa022555f494b7a0 364 Pfam PF01872 RibD C-terminal domain 148 355 5.1E-57 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 HW35_07770 e458246a402ecbc5591001a431de3292 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 26 301 7.3E-94 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HW35_07770 e458246a402ecbc5591001a431de3292 313 SUPERFAMILY SSF160240 226 299 2.88E-8 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 HW35_07770 e458246a402ecbc5591001a431de3292 313 SUPERFAMILY SSF161111 25 223 2.75E-56 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily HW35_07770 e458246a402ecbc5591001a431de3292 313 Pfam PF01545 Cation efflux family 32 222 5.1E-47 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HW35_07770 e458246a402ecbc5591001a431de3292 313 Gene3D G3DSA:1.20.1510.10 26 222 5.0E-45 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily HW35_03740 589cdbb0ca50cc77bf016ec722bd9d90 389 SUPERFAMILY SSF89550 2 245 4.32E-17 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HW35_03740 589cdbb0ca50cc77bf016ec722bd9d90 389 Gene3D G3DSA:3.20.20.140 1 240 1.6E-20 T 12-10-2018 HW35_03740 589cdbb0ca50cc77bf016ec722bd9d90 389 SUPERFAMILY SSF47781 310 369 6.3E-7 T 12-10-2018 IPR010994 RuvA domain 2-like HW35_03740 589cdbb0ca50cc77bf016ec722bd9d90 389 Pfam PF13263 PHP-associated 195 243 7.9E-7 T 12-10-2018 HW35_04770 4d2c6e26a05937ebe3c75322c4054cfc 88 Hamap MF_01507 UPF0297 protein . 1 85 28.908 T 12-10-2018 IPR009309 Uncharacterised protein family UPF0297 HW35_04770 4d2c6e26a05937ebe3c75322c4054cfc 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 1.1E-37 T 12-10-2018 IPR009309 Uncharacterised protein family UPF0297 HW35_04770 4d2c6e26a05937ebe3c75322c4054cfc 88 PIRSF PIRSF037258 1 88 4.9E-46 T 12-10-2018 IPR009309 Uncharacterised protein family UPF0297 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 SMART SM01228 545 616 3.7E-44 T 12-10-2018 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 6.5E-298 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 Gene3D G3DSA:1.10.150.570 568 620 6.5E-25 T 12-10-2018 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 42.767 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 Pfam PF13932 GidA associated domain 401 615 3.5E-80 T 12-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 7.9E-6 T 12-10-2018 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 7.9E-6 T 12-10-2018 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 Gene3D G3DSA:3.50.50.60 296 458 6.2E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 Gene3D G3DSA:3.50.50.60 1 227 3.9E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 Pfam PF01134 Glucose inhibited division protein A 9 398 6.5E-173 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 Gene3D G3DSA:1.10.10.1800 459 549 9.5E-27 T 12-10-2018 HW35_09940 5791b88dfb30f6d02a5c820c983e3442 629 SUPERFAMILY SSF51905 7 261 9.5E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_04530 81cc3268bd7a8de836e0eaf5d16cbcef 313 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 306 1.4E-102 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HW35_04530 81cc3268bd7a8de836e0eaf5d16cbcef 313 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 312 1.5E-108 T 12-10-2018 HW35_04530 81cc3268bd7a8de836e0eaf5d16cbcef 313 Gene3D G3DSA:3.40.50.150 116 312 2.6E-62 T 12-10-2018 HW35_04530 81cc3268bd7a8de836e0eaf5d16cbcef 313 PIRSF PIRSF000401 1 313 5.2E-112 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HW35_04530 81cc3268bd7a8de836e0eaf5d16cbcef 313 SUPERFAMILY SSF53335 94 309 2.99E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_04530 81cc3268bd7a8de836e0eaf5d16cbcef 313 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 312 36.491 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 SUPERFAMILY SSF52313 6 228 1.28E-100 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily HW35_16765 720d7b54502acc1407c98bfd6211c161 234 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 44.049 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 Gene3D G3DSA:3.40.50.10490 10 215 2.0E-97 T 12-10-2018 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 Pfam PF00318 Ribosomal protein S2 9 224 5.4E-103 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 Gene3D G3DSA:1.10.287.610 97 152 2.0E-97 T 12-10-2018 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 3.7E-114 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 PRINTS PR00395 Ribosomal protein S2 signature 37 46 4.8E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 PRINTS PR00395 Ribosomal protein S2 signature 196 210 4.8E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 PRINTS PR00395 Ribosomal protein S2 signature 87 104 4.8E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 PRINTS PR00395 Ribosomal protein S2 signature 175 186 4.8E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 PRINTS PR00395 Ribosomal protein S2 signature 158 175 4.8E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16765 720d7b54502acc1407c98bfd6211c161 234 PRINTS PR00395 Ribosomal protein S2 signature 6 24 4.8E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_05950 cc207dc0f1bd7a89aff7d8d4c7a730e4 931 Gene3D G3DSA:3.40.50.300 564 843 3.6E-111 T 12-10-2018 HW35_05950 cc207dc0f1bd7a89aff7d8d4c7a730e4 931 SUPERFAMILY SSF52540 541 832 1.59E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05950 cc207dc0f1bd7a89aff7d8d4c7a730e4 931 SMART SM00843 854 919 3.4E-36 T 12-10-2018 IPR018541 FtsK gamma domain HW35_05950 cc207dc0f1bd7a89aff7d8d4c7a730e4 931 Pfam PF01580 FtsK/SpoIIIE family 568 707 1.3E-46 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HW35_05950 cc207dc0f1bd7a89aff7d8d4c7a730e4 931 SMART SM00382 602 780 1.4E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_05950 cc207dc0f1bd7a89aff7d8d4c7a730e4 931 Gene3D G3DSA:1.10.10.10 848 915 4.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_05950 cc207dc0f1bd7a89aff7d8d4c7a730e4 931 SUPERFAMILY SSF46785 855 920 1.86E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_05950 cc207dc0f1bd7a89aff7d8d4c7a730e4 931 Pfam PF09397 Ftsk gamma domain 855 917 2.7E-28 T 12-10-2018 IPR018541 FtsK gamma domain HW35_05950 cc207dc0f1bd7a89aff7d8d4c7a730e4 931 Gene3D G3DSA:3.30.980.40 461 563 1.4E-35 T 12-10-2018 HW35_13090 ce132312c03767f8e22096f136c06f02 338 SUPERFAMILY SSF89000 285 332 1.49E-17 T 12-10-2018 HW35_13090 ce132312c03767f8e22096f136c06f02 338 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 269 331 2.0E-22 T 12-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 HW35_13090 ce132312c03767f8e22096f136c06f02 338 Gene3D G3DSA:3.20.20.70 1 265 1.0E-86 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_13090 ce132312c03767f8e22096f136c06f02 338 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 4 333 2.1E-161 T 12-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 HW35_13090 ce132312c03767f8e22096f136c06f02 338 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 338 180.371 T 12-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 HW35_13090 ce132312c03767f8e22096f136c06f02 338 SUPERFAMILY SSF51569 1 268 4.94E-68 T 12-10-2018 HW35_13090 ce132312c03767f8e22096f136c06f02 338 Gene3D G3DSA:1.10.8.60 272 336 8.9E-30 T 12-10-2018 HW35_13090 ce132312c03767f8e22096f136c06f02 338 Pfam PF07836 DmpG-like communication domain 271 332 2.2E-32 T 12-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 HW35_13090 ce132312c03767f8e22096f136c06f02 338 Pfam PF00682 HMGL-like 5 259 3.3E-59 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 SMART SM01130 2 289 1.1E-141 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 SUPERFAMILY SSF51569 2 287 4.61E-104 T 12-10-2018 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 Pfam PF00701 Dihydrodipicolinate synthetase family 3 288 9.6E-110 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 3.9E-36 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 3.9E-36 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 3.9E-36 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 3.9E-36 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 65.915 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 287 7.1E-112 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 PIRSF PIRSF001365 1 293 3.3E-100 T 12-10-2018 IPR002220 DapA-like GO:0016829 HW35_01920 81597f5eaf52a2bc7001849e0a32a745 293 Gene3D G3DSA:3.20.20.70 1 288 1.5E-116 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_12405 afda774e8bc6eb21f8dc9acd9534f42d 217 Gene3D G3DSA:1.10.3720.10 1 216 1.3E-58 T 12-10-2018 IPR035906 MetI-like superfamily HW35_12405 afda774e8bc6eb21f8dc9acd9534f42d 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 108 2.9E-27 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 HW35_12405 afda774e8bc6eb21f8dc9acd9534f42d 217 SUPERFAMILY SSF161098 13 199 4.06E-48 T 12-10-2018 IPR035906 MetI-like superfamily HW35_12405 afda774e8bc6eb21f8dc9acd9534f42d 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 3.6E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_01265 ddc0b9c9cdeb4770b9784c7c82287bd8 275 Gene3D G3DSA:3.40.630.30 1 133 3.1E-11 T 12-10-2018 HW35_01265 ddc0b9c9cdeb4770b9784c7c82287bd8 275 Gene3D G3DSA:3.40.630.30 142 275 2.3E-22 T 12-10-2018 HW35_01265 ddc0b9c9cdeb4770b9784c7c82287bd8 275 SUPERFAMILY SSF55729 142 271 9.62E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_01265 ddc0b9c9cdeb4770b9784c7c82287bd8 275 Pfam PF00583 Acetyltransferase (GNAT) family 159 262 1.3E-14 T 12-10-2018 IPR000182 GNAT domain HW35_01265 ddc0b9c9cdeb4770b9784c7c82287bd8 275 Pfam PF00583 Acetyltransferase (GNAT) family 39 103 2.2E-6 T 12-10-2018 IPR000182 GNAT domain HW35_01265 ddc0b9c9cdeb4770b9784c7c82287bd8 275 SUPERFAMILY SSF55729 3 116 7.09E-13 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_02390 4a1bb38ca877f3866a42e32a69ab2286 655 Pfam PF00884 Sulfatase 244 535 6.2E-41 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 HW35_02390 4a1bb38ca877f3866a42e32a69ab2286 655 PIRSF PIRSF005091 1 619 2.1E-182 T 12-10-2018 IPR012160 Lipoteichoic acid synthase-like HW35_02390 4a1bb38ca877f3866a42e32a69ab2286 655 Gene3D G3DSA:3.40.720.10 235 545 9.2E-78 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 HW35_02390 4a1bb38ca877f3866a42e32a69ab2286 655 SUPERFAMILY SSF53649 241 632 1.46E-74 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 HW35_04620 cc860f0beb6fd8da3b92d078cfe068d2 420 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 4.8E-131 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_04620 cc860f0beb6fd8da3b92d078cfe068d2 420 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 3.1E-49 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_04620 cc860f0beb6fd8da3b92d078cfe068d2 420 Pfam PF08388 Group II intron, maturase-specific domain 288 360 1.7E-20 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_04620 cc860f0beb6fd8da3b92d078cfe068d2 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_04620 cc860f0beb6fd8da3b92d078cfe068d2 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_04620 cc860f0beb6fd8da3b92d078cfe068d2 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_04620 cc860f0beb6fd8da3b92d078cfe068d2 420 SUPERFAMILY SSF56672 23 346 1.72E-58 T 12-10-2018 HW35_06180 fad4dab26c25706911e80bdce3381a7b 338 Pfam PF13379 NMT1-like family 45 267 2.7E-22 T 12-10-2018 HW35_06180 fad4dab26c25706911e80bdce3381a7b 338 Gene3D G3DSA:3.40.190.10 44 313 2.1E-52 T 12-10-2018 HW35_06180 fad4dab26c25706911e80bdce3381a7b 338 SUPERFAMILY SSF53850 37 263 7.82E-35 T 12-10-2018 HW35_06180 fad4dab26c25706911e80bdce3381a7b 338 Gene3D G3DSA:3.40.190.10 120 223 2.1E-52 T 12-10-2018 HW35_14980 5316c654072e6e5b418887296645b4bb 309 Hamap MF_00323 Ferrochelatase [hemH]. 4 308 32.362 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 HW35_14980 5316c654072e6e5b418887296645b4bb 309 ProSitePatterns PS00534 Ferrochelatase signature. 178 196 - T 12-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 HW35_14980 5316c654072e6e5b418887296645b4bb 309 TIGRFAM TIGR00109 hemH: ferrochelatase 2 307 6.1E-101 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 HW35_14980 5316c654072e6e5b418887296645b4bb 309 Gene3D G3DSA:3.40.50.1400 148 289 1.5E-107 T 12-10-2018 HW35_14980 5316c654072e6e5b418887296645b4bb 309 SUPERFAMILY SSF53800 3 308 4.74E-91 T 12-10-2018 HW35_14980 5316c654072e6e5b418887296645b4bb 309 Pfam PF00762 Ferrochelatase 5 306 1.5E-83 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 HW35_14980 5316c654072e6e5b418887296645b4bb 309 Gene3D G3DSA:3.40.50.1400 8 304 1.5E-107 T 12-10-2018 HW35_16855 8285bd565be71c32dfd8b82083fe7644 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 2.2E-43 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16855 8285bd565be71c32dfd8b82083fe7644 89 SUPERFAMILY SSF47060 3 89 4.12E-38 T 12-10-2018 IPR009068 S15/NS1, RNA-binding HW35_16855 8285bd565be71c32dfd8b82083fe7644 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.614 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16855 8285bd565be71c32dfd8b82083fe7644 89 SMART SM01387 8 88 8.3E-55 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16855 8285bd565be71c32dfd8b82083fe7644 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16855 8285bd565be71c32dfd8b82083fe7644 89 Gene3D G3DSA:1.10.287.10 2 89 4.8E-39 T 12-10-2018 HW35_16855 8285bd565be71c32dfd8b82083fe7644 89 Pfam PF00312 Ribosomal protein S15 8 88 1.0E-39 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16855 8285bd565be71c32dfd8b82083fe7644 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 88 9.0E-37 T 12-10-2018 HW35_13285 91ba89b6ad445cac96c038c0906e7ba9 368 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 241 260 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 HW35_13285 91ba89b6ad445cac96c038c0906e7ba9 368 SMART SM01329 4 350 2.6E-199 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HW35_13285 91ba89b6ad445cac96c038c0906e7ba9 368 Gene3D G3DSA:3.40.718.10 1 364 9.3E-153 T 12-10-2018 HW35_13285 91ba89b6ad445cac96c038c0906e7ba9 368 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 350 1.5E-136 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HW35_13285 91ba89b6ad445cac96c038c0906e7ba9 368 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 354 49.731 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 HW35_13285 91ba89b6ad445cac96c038c0906e7ba9 368 SUPERFAMILY SSF53659 4 354 2.11E-122 T 12-10-2018 HW35_13285 91ba89b6ad445cac96c038c0906e7ba9 368 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 349 2.3E-160 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 HW35_12530 0f1656255702b186a05867d23e193deb 334 SUPERFAMILY SSF47413 2 60 3.75E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_12530 0f1656255702b186a05867d23e193deb 334 Gene3D G3DSA:1.10.260.40 1 60 3.0E-24 T 12-10-2018 HW35_12530 0f1656255702b186a05867d23e193deb 334 Gene3D G3DSA:3.40.50.2300 63 321 3.0E-80 T 12-10-2018 HW35_12530 0f1656255702b186a05867d23e193deb 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 3.3E-22 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12530 0f1656255702b186a05867d23e193deb 334 Gene3D G3DSA:3.40.50.2300 161 326 3.0E-80 T 12-10-2018 HW35_12530 0f1656255702b186a05867d23e193deb 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 9.1E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12530 0f1656255702b186a05867d23e193deb 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 9.1E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12530 0f1656255702b186a05867d23e193deb 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 HW35_12530 0f1656255702b186a05867d23e193deb 334 SMART SM00354 2 72 4.4E-37 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12530 0f1656255702b186a05867d23e193deb 334 SUPERFAMILY SSF53822 62 330 1.3E-76 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_12530 0f1656255702b186a05867d23e193deb 334 Pfam PF13377 Periplasmic binding protein-like domain 171 329 1.8E-34 T 12-10-2018 HW35_05925 a9863458f31614e66f2bf0905f4e2ec0 358 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 102 5.5E-42 T 12-10-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HW35_05925 a9863458f31614e66f2bf0905f4e2ec0 358 Pfam PF01817 Chorismate mutase type II 10 87 2.5E-19 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HW35_05925 a9863458f31614e66f2bf0905f4e2ec0 358 Pfam PF00793 DAHP synthetase I family 110 347 2.3E-84 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 HW35_05925 a9863458f31614e66f2bf0905f4e2ec0 358 SUPERFAMILY SSF51569 38 352 5.95E-102 T 12-10-2018 HW35_05925 a9863458f31614e66f2bf0905f4e2ec0 358 Gene3D G3DSA:3.20.20.70 93 357 1.5E-101 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_05925 a9863458f31614e66f2bf0905f4e2ec0 358 Gene3D G3DSA:1.20.59.10 8 92 2.2E-28 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HW35_05925 a9863458f31614e66f2bf0905f4e2ec0 358 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 350 6.1E-122 T 12-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 HW35_05925 a9863458f31614e66f2bf0905f4e2ec0 358 SMART SM00830 10 89 6.3E-24 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HW35_00970 a28ab4439ffc2b373c754874cabe740b 349 SUPERFAMILY SSF100950 5 342 4.81E-125 T 12-10-2018 IPR037171 NagB/RpiA transferase-like HW35_00970 a28ab4439ffc2b373c754874cabe740b 349 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 7 336 4.9E-141 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HW35_00970 a28ab4439ffc2b373c754874cabe740b 349 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 33 336 7.5E-123 T 12-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HW35_00970 a28ab4439ffc2b373c754874cabe740b 349 Gene3D G3DSA:1.20.120.420 2 148 5.4E-49 T 12-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HW35_00970 a28ab4439ffc2b373c754874cabe740b 349 Gene3D G3DSA:3.40.50.10470 149 349 2.9E-72 T 12-10-2018 HW35_00970 a28ab4439ffc2b373c754874cabe740b 349 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 5 347 40.476 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HW35_00970 a28ab4439ffc2b373c754874cabe740b 349 Pfam PF01008 Initiation factor 2 subunit family 47 336 7.0E-90 T 12-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 HW35_05660 65051ce9becd949451314761f10af06b 312 SUPERFAMILY SSF56327 150 310 1.11E-52 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HW35_05660 65051ce9becd949451314761f10af06b 312 Gene3D G3DSA:3.40.50.720 1 149 9.7E-61 T 12-10-2018 HW35_05660 65051ce9becd949451314761f10af06b 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 46.6 T 12-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 HW35_05660 65051ce9becd949451314761f10af06b 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 3.1E-162 T 12-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 HW35_05660 65051ce9becd949451314761f10af06b 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 9.3E-31 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_05660 65051ce9becd949451314761f10af06b 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 9.3E-31 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_05660 65051ce9becd949451314761f10af06b 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 9.3E-31 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_05660 65051ce9becd949451314761f10af06b 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 9.3E-31 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_05660 65051ce9becd949451314761f10af06b 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 9.3E-31 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_05660 65051ce9becd949451314761f10af06b 312 SUPERFAMILY SSF51735 3 147 4.88E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_05660 65051ce9becd949451314761f10af06b 312 Gene3D G3DSA:3.90.110.10 150 310 1.6E-62 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HW35_05660 65051ce9becd949451314761f10af06b 312 PIRSF PIRSF000102 2 311 2.6E-105 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HW35_05660 65051ce9becd949451314761f10af06b 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 309 9.0E-28 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 HW35_05660 65051ce9becd949451314761f10af06b 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 3.4E-42 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 SUPERFAMILY SSF53187 421 594 1.82E-53 T 12-10-2018 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Pfam PF08239 Bacterial SH3 domain 351 402 2.9E-11 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Pfam PF08239 Bacterial SH3 domain 112 162 2.5E-13 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Pfam PF08239 Bacterial SH3 domain 189 237 3.3E-14 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Pfam PF08239 Bacterial SH3 domain 37 87 1.8E-8 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Pfam PF08239 Bacterial SH3 domain 264 314 1.0E-12 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Gene3D G3DSA:2.30.30.40 179 246 6.2E-18 T 12-10-2018 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Gene3D G3DSA:2.30.30.40 104 171 2.0E-14 T 12-10-2018 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 SMART SM00287 257 316 3.6E-8 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 SMART SM00287 99 164 3.1E-4 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 SMART SM00287 179 241 4.1E-8 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 SMART SM00287 26 90 9.0E-14 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 SMART SM00287 340 404 1.8E-14 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 SMART SM00646 483 591 9.8E-35 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 PIRSF PIRSF037846 168 345 4.6E-29 T 12-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 PIRSF PIRSF037846 1 181 5.4E-42 T 12-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 PIRSF PIRSF037846 245 595 4.7E-108 T 12-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Gene3D G3DSA:3.40.630.40 421 596 2.5E-57 T 12-10-2018 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 424 591 1.3E-48 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Gene3D G3DSA:2.30.30.40 247 316 1.6E-17 T 12-10-2018 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Gene3D G3DSA:2.30.30.40 21 91 3.3E-16 T 12-10-2018 HW35_04890 1e057976e91275cfb5b78b72ae6ae445 597 Gene3D G3DSA:2.30.30.40 335 404 9.2E-15 T 12-10-2018 HW35_00940 7e13a515609feeb6f079cc5ac57d4932 468 SUPERFAMILY SSF53383 78 467 2.75E-49 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_00940 7e13a515609feeb6f079cc5ac57d4932 468 Gene3D G3DSA:3.40.640.10 99 364 5.4E-162 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_00940 7e13a515609feeb6f079cc5ac57d4932 468 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 5 465 6.0E-171 T 12-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 HW35_00940 7e13a515609feeb6f079cc5ac57d4932 468 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 468 185.857 T 12-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 HW35_00940 7e13a515609feeb6f079cc5ac57d4932 468 Pfam PF03841 L-seryl-tRNA selenium transferase 87 453 1.4E-146 T 12-10-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 HW35_00940 7e13a515609feeb6f079cc5ac57d4932 468 Gene3D G3DSA:3.90.1150.110 27 457 5.4E-162 T 12-10-2018 HW35_14920 b0116d005805e725373d51815498d68e 191 SMART SM00347 35 135 9.7E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_14920 b0116d005805e725373d51815498d68e 191 Gene3D G3DSA:1.10.10.10 1 165 2.6E-45 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_14920 b0116d005805e725373d51815498d68e 191 SUPERFAMILY SSF46785 6 142 2.61E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_14920 b0116d005805e725373d51815498d68e 191 Pfam PF01047 MarR family 42 99 7.3E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_14920 b0116d005805e725373d51815498d68e 191 ProSitePatterns PS01117 MarR-type HTH domain signature. 74 108 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site HW35_17050 374cf47b8241c7689cfdcafd4343780c 244 Pfam PF03741 Integral membrane protein TerC family 36 205 1.6E-50 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 HW35_17050 374cf47b8241c7689cfdcafd4343780c 244 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 33 229 2.3E-68 T 12-10-2018 IPR022493 Integral membrane YkoY HW35_17420 26a2c953903758577eb8b61358125e5c 255 Pfam PF02679 (2R)-phospho-3-sulfolactate synthase (ComA) 8 242 1.5E-74 T 12-10-2018 IPR003830 (2R)-phospho-3-sulpholactate synthase, ComA KEGG: 00680+4.4.1.19 HW35_17420 26a2c953903758577eb8b61358125e5c 255 SUPERFAMILY SSF102110 3 245 1.02E-72 T 12-10-2018 IPR036112 (2R)-phospho-3-sulpholactate synthase, ComA superfamily KEGG: 00680+4.4.1.19 HW35_17420 26a2c953903758577eb8b61358125e5c 255 Gene3D G3DSA:3.20.20.70 2 249 2.3E-81 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 Gene3D G3DSA:2.40.340.10 335 410 1.1E-11 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 187 323 3.6E-31 T 12-10-2018 IPR001453 MoaB/Mog domain HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 Gene3D G3DSA:2.170.190.11 50 150 6.6E-98 T 12-10-2018 HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 SUPERFAMILY SSF63867 338 413 1.07E-15 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 SMART SM00852 189 327 1.2E-37 T 12-10-2018 IPR001453 MoaB/Mog domain HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 Gene3D G3DSA:3.40.980.10 184 326 6.6E-98 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 Pfam PF03453 MoeA N-terminal region (domain I and II) 10 176 1.5E-39 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 Gene3D G3DSA:3.90.105.10 29 183 6.6E-98 T 12-10-2018 HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 SUPERFAMILY SSF63882 8 185 2.09E-51 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 Pfam PF00994 Probable molybdopterin binding domain 191 326 7.4E-25 T 12-10-2018 IPR001453 MoaB/Mog domain HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 SUPERFAMILY SSF53218 187 328 3.4E-38 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily HW35_15210 22feef36541b50ed19d6d231c5ae18a4 421 Pfam PF03454 MoeA C-terminal region (domain IV) 340 411 2.1E-15 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_12190 6aca1b7828174566202b059d409f603d 504 ProSitePatterns PS01303 BCCT family of transporters signature. 307 316 - T 12-10-2018 IPR018093 BCCT transporter, conserved site HW35_12190 6aca1b7828174566202b059d409f603d 504 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 7 489 2.7E-191 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 HW35_12190 6aca1b7828174566202b059d409f603d 504 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 45 490 3.1E-161 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 HW35_09435 86a45a6adf2321092d35197ea88bc9d7 158 Gene3D G3DSA:3.90.1170.40 3 148 6.5E-54 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 HW35_09435 86a45a6adf2321092d35197ea88bc9d7 158 Pfam PF02391 MoaE protein 9 120 6.4E-37 T 12-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 HW35_09435 86a45a6adf2321092d35197ea88bc9d7 158 SUPERFAMILY SSF54690 6 139 1.18E-46 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 SUPERFAMILY SSF52794 419 497 5.02E-12 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Gene3D G3DSA:3.40.50.2300 419 503 4.7E-11 T 12-10-2018 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 SUPERFAMILY SSF46785 88 150 3.68E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 SUPERFAMILY SSF63520 202 302 3.27E-22 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Pfam PF08279 HTH domain 6 63 1.1E-10 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Gene3D G3DSA:1.10.1790.10 315 411 3.1E-22 T 12-10-2018 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Gene3D G3DSA:1.10.10.10 3 82 2.6E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 SUPERFAMILY SSF55804 547 689 1.96E-18 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Gene3D G3DSA:3.40.930.10 540 691 1.6E-15 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Gene3D G3DSA:1.10.1790.10 202 302 6.3E-22 T 12-10-2018 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 SUPERFAMILY SSF46785 1 67 8.53E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 556 690 4.4E-16 T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Pfam PF00874 PRD domain 322 409 2.8E-22 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Pfam PF00874 PRD domain 211 298 1.8E-20 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Gene3D G3DSA:1.10.10.10 83 150 3.3E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 SUPERFAMILY SSF63520 310 411 3.79E-23 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_11255 c6cea7a0713a064bc4cc682d9b56b260 708 Pfam PF05043 Mga helix-turn-helix domain 86 162 7.7E-5 T 12-10-2018 IPR007737 Mga helix-turn-helix domain HW35_03800 cfff10112cd536989069806e035c82a9 419 Gene3D G3DSA:3.30.70.270 12 173 9.2E-33 T 12-10-2018 HW35_03800 cfff10112cd536989069806e035c82a9 419 Gene3D G3DSA:3.30.1490.100 258 364 2.1E-16 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HW35_03800 cfff10112cd536989069806e035c82a9 419 Pfam PF00817 impB/mucB/samB family 15 164 2.4E-28 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HW35_03800 cfff10112cd536989069806e035c82a9 419 SUPERFAMILY SSF100879 258 357 2.75E-16 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HW35_03800 cfff10112cd536989069806e035c82a9 419 SUPERFAMILY SSF56672 11 247 1.6E-53 T 12-10-2018 HW35_03800 cfff10112cd536989069806e035c82a9 419 Pfam PF11798 IMS family HHH motif 180 211 3.9E-8 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 HW35_03800 cfff10112cd536989069806e035c82a9 419 Pfam PF11799 impB/mucB/samB family C-terminal domain 258 361 9.0E-19 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HW35_03800 cfff10112cd536989069806e035c82a9 419 Gene3D G3DSA:2.30.40.20 29 83 9.2E-33 T 12-10-2018 HW35_03800 cfff10112cd536989069806e035c82a9 419 Gene3D G3DSA:1.10.150.20 191 243 1.3E-16 T 12-10-2018 HW35_15700 26a3853afa7c02997c77864eccbd1418 174 Gene3D G3DSA:2.60.120.10 1 167 6.3E-58 T 12-10-2018 IPR014710 RmlC-like jelly roll fold HW35_15700 26a3853afa7c02997c77864eccbd1418 174 Pfam PF03079 ARD/ARD' family 3 165 4.3E-46 T 12-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 HW35_15700 26a3853afa7c02997c77864eccbd1418 174 SUPERFAMILY SSF51182 13 171 1.83E-32 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily HW35_15700 26a3853afa7c02997c77864eccbd1418 174 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 5 172 28.992 T 12-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 HW35_00215 d00815734e196477d05fad095032a75f 497 Gene3D G3DSA:3.30.750.140 334 442 6.2E-15 T 12-10-2018 IPR038610 FliK-like, C-terminal domain superfamily HW35_00215 d00815734e196477d05fad095032a75f 497 Pfam PF02120 Flagellar hook-length control protein FliK 359 430 1.1E-16 T 12-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal HW35_02850 1e8bec0ac22493a522519f32bb1df4c8 320 Gene3D G3DSA:3.30.572.10 4 320 1.7E-136 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HW35_02850 1e8bec0ac22493a522519f32bb1df4c8 320 Pfam PF00303 Thymidylate synthase 7 320 8.2E-111 T 12-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HW35_02850 1e8bec0ac22493a522519f32bb1df4c8 320 SUPERFAMILY SSF55831 4 320 2.22E-127 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HW35_02850 1e8bec0ac22493a522519f32bb1df4c8 320 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 7 320 6.6E-151 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HW35_02850 1e8bec0ac22493a522519f32bb1df4c8 320 PRINTS PR00108 Thymidylate synthase family signature 169 188 2.1E-40 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HW35_02850 1e8bec0ac22493a522519f32bb1df4c8 320 PRINTS PR00108 Thymidylate synthase family signature 215 241 2.1E-40 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HW35_02850 1e8bec0ac22493a522519f32bb1df4c8 320 PRINTS PR00108 Thymidylate synthase family signature 46 67 2.1E-40 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HW35_02850 1e8bec0ac22493a522519f32bb1df4c8 320 PRINTS PR00108 Thymidylate synthase family signature 253 270 2.1E-40 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HW35_02850 1e8bec0ac22493a522519f32bb1df4c8 320 ProSitePatterns PS00091 Thymidylate synthase active site. 180 210 - T 12-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HW35_02850 1e8bec0ac22493a522519f32bb1df4c8 320 Hamap MF_00008 Thymidylate synthase [thyA]. 5 320 37.977 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HW35_15065 4f95e07b017da7832d281d26a745aeac 1167 SUPERFAMILY SSF52540 309 752 2.76E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15065 4f95e07b017da7832d281d26a745aeac 1167 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1163 0.0 T 12-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 HW35_15065 4f95e07b017da7832d281d26a745aeac 1167 Gene3D G3DSA:3.40.50.300 281 437 2.6E-29 T 12-10-2018 HW35_15065 4f95e07b017da7832d281d26a745aeac 1167 Gene3D G3DSA:3.40.50.300 558 698 9.2E-46 T 12-10-2018 HW35_15065 4f95e07b017da7832d281d26a745aeac 1167 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1163 61.713 T 12-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 HW35_15065 4f95e07b017da7832d281d26a745aeac 1167 Pfam PF12705 PD-(D/E)XK nuclease superfamily 790 1132 4.0E-61 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type HW35_15065 4f95e07b017da7832d281d26a745aeac 1167 Gene3D G3DSA:3.40.50.300 1 140 6.0E-33 T 12-10-2018 HW35_15065 4f95e07b017da7832d281d26a745aeac 1167 Gene3D G3DSA:3.40.50.300 141 276 4.1E-29 T 12-10-2018 HW35_15065 4f95e07b017da7832d281d26a745aeac 1167 Pfam PF13361 UvrD-like helicase C-terminal domain 307 668 2.4E-7 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 Pfam PF03793 PASTA domain 604 657 7.7E-9 T 12-10-2018 IPR005543 PASTA domain HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 Pfam PF03793 PASTA domain 662 714 2.8E-5 T 12-10-2018 IPR005543 PASTA domain HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 SMART SM00740 660 716 0.87 T 12-10-2018 IPR005543 PASTA domain HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 SMART SM00740 599 659 2.0E-10 T 12-10-2018 IPR005543 PASTA domain HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 SUPERFAMILY SSF54184 661 715 3.01E-11 T 12-10-2018 HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 Pfam PF03717 Penicillin-binding Protein dimerisation domain 58 225 3.2E-25 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 Gene3D G3DSA:3.30.70.2110 79 165 3.3E-58 T 12-10-2018 HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 Gene3D G3DSA:3.90.1310.10 60 210 3.3E-58 T 12-10-2018 HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 Gene3D G3DSA:2.20.70.70 57 230 3.3E-58 T 12-10-2018 HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 Pfam PF00905 Penicillin binding protein transpeptidase domain 272 568 1.5E-86 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 SUPERFAMILY SSF56519 57 243 4.05E-47 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 Gene3D G3DSA:3.40.710.10 237 593 8.9E-102 T 12-10-2018 HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 SUPERFAMILY SSF54184 600 659 1.06E-12 T 12-10-2018 HW35_16295 9102937c92d9ae235a69dd25d5bae266 744 SUPERFAMILY SSF56601 194 616 1.04E-97 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_03835 02153fed2c2112108e8ccaae11218bbc 307 SUPERFAMILY SSF56281 1 305 4.2E-86 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_03835 02153fed2c2112108e8ccaae11218bbc 307 Gene3D G3DSA:3.60.15.10 1 304 9.0E-106 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_03835 02153fed2c2112108e8ccaae11218bbc 307 Hamap MF_01818 Ribonuclease BN [rbn]. 1 304 42.136 T 12-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 HW35_03835 02153fed2c2112108e8ccaae11218bbc 307 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 304 1.5E-119 T 12-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 HW35_03835 02153fed2c2112108e8ccaae11218bbc 307 Pfam PF00753 Metallo-beta-lactamase superfamily 29 142 9.1E-10 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_10095 206727b5067ba74a60168e7e9c809ea4 105 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 6 100 23.812 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HW35_10095 206727b5067ba74a60168e7e9c809ea4 105 Pfam PF02575 YbaB/EbfC DNA-binding family 12 102 2.2E-37 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HW35_10095 206727b5067ba74a60168e7e9c809ea4 105 PIRSF PIRSF004555 4 105 1.8E-40 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HW35_10095 206727b5067ba74a60168e7e9c809ea4 105 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 103 1.6E-32 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HW35_10095 206727b5067ba74a60168e7e9c809ea4 105 Gene3D G3DSA:3.30.1310.10 2 105 6.2E-41 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily HW35_10095 206727b5067ba74a60168e7e9c809ea4 105 SUPERFAMILY SSF82607 12 104 2.09E-35 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily HW35_13770 f8bfa81cffa0c9d13c4a2a4acc1ac383 458 Gene3D G3DSA:3.40.1350.30 135 290 7.1E-114 T 12-10-2018 HW35_13770 f8bfa81cffa0c9d13c4a2a4acc1ac383 458 Pfam PF01938 TRAM domain 11 63 3.4E-12 T 12-10-2018 IPR002792 TRAM domain HW35_13770 f8bfa81cffa0c9d13c4a2a4acc1ac383 458 Gene3D G3DSA:3.40.50.150 86 451 7.1E-114 T 12-10-2018 HW35_13770 f8bfa81cffa0c9d13c4a2a4acc1ac383 458 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 389 420 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site HW35_13770 f8bfa81cffa0c9d13c4a2a4acc1ac383 458 SUPERFAMILY SSF50249 4 64 5.43E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_13770 f8bfa81cffa0c9d13c4a2a4acc1ac383 458 Gene3D G3DSA:2.40.50.140 1 84 7.3E-24 T 12-10-2018 HW35_13770 f8bfa81cffa0c9d13c4a2a4acc1ac383 458 SUPERFAMILY SSF53335 73 457 5.28E-81 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_13770 f8bfa81cffa0c9d13c4a2a4acc1ac383 458 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 93 458 7.5E-23 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 HW35_13770 f8bfa81cffa0c9d13c4a2a4acc1ac383 458 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 21 450 6.9E-182 T 12-10-2018 HW35_13770 f8bfa81cffa0c9d13c4a2a4acc1ac383 458 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 440 450 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site HW35_04145 b6e7ff7300e118a209d45a9f4102e22d 487 Gene3D G3DSA:3.40.640.10 86 326 7.8E-61 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_04145 b6e7ff7300e118a209d45a9f4102e22d 487 SUPERFAMILY SSF53383 14 483 2.13E-117 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_04145 b6e7ff7300e118a209d45a9f4102e22d 487 Pfam PF02347 Glycine cleavage system P-protein 37 387 7.8E-12 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 HW35_04145 b6e7ff7300e118a209d45a9f4102e22d 487 Gene3D G3DSA:3.90.1150.10 338 470 2.6E-49 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_04145 b6e7ff7300e118a209d45a9f4102e22d 487 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 60.25 T 12-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 HW35_05095 0d338d88cdf3729967a224ce8397bf85 223 Pfam PF04002 RadC-like JAB domain 102 221 9.7E-49 T 12-10-2018 IPR025657 RadC-like JAB domain HW35_05095 0d338d88cdf3729967a224ce8397bf85 223 Gene3D G3DSA:1.10.150.20 46 86 8.5E-7 T 12-10-2018 HW35_05095 0d338d88cdf3729967a224ce8397bf85 223 SUPERFAMILY SSF102712 152 191 2.09E-5 T 12-10-2018 HW35_05095 0d338d88cdf3729967a224ce8397bf85 223 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 172 177 - T 12-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site HW35_05095 0d338d88cdf3729967a224ce8397bf85 223 SUPERFAMILY SSF47781 14 89 1.94E-8 T 12-10-2018 IPR010994 RuvA domain 2-like HW35_05095 0d338d88cdf3729967a224ce8397bf85 223 TIGRFAM TIGR00608 radc: DNA repair protein RadC 10 223 1.4E-86 T 12-10-2018 IPR001405 Uncharacterised protein family UPF0758 HW35_05095 0d338d88cdf3729967a224ce8397bf85 223 Gene3D G3DSA:3.40.140.10 99 223 9.9E-49 T 12-10-2018 HW35_14845 d0d8913e981f7f7d35eb9cf9c1112ef5 115 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 6 108 3.1E-24 T 12-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA HW35_14845 d0d8913e981f7f7d35eb9cf9c1112ef5 115 Gene3D G3DSA:1.20.1500.10 2 113 2.1E-37 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily HW35_14845 d0d8913e981f7f7d35eb9cf9c1112ef5 115 SUPERFAMILY SSF158622 3 113 6.15E-35 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily HW35_14845 d0d8913e981f7f7d35eb9cf9c1112ef5 115 Hamap MF_01526 UPF0342 protein . 2 113 18.887 T 12-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 SUPERFAMILY SSF47384 194 263 2.55E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 Gene3D G3DSA:3.30.565.10 260 411 1.5E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 306 411 8.1E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 261 1.2E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 SMART SM00388 199 265 4.9E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 Gene3D G3DSA:1.10.287.130 185 259 2.4E-19 T 12-10-2018 HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 SMART SM00387 306 413 2.7E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 SUPERFAMILY SSF55874 255 413 7.73E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 410 1.9E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 371 1.9E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 1.9E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_14645 3cd4cceddd37bc58d5d14f92b84103fd 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 357 1.9E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_04945 09e31cbbdda282d1a6fc6d89f4133884 92 SMART SM01323 2 84 2.6E-46 T 12-10-2018 IPR003849 Preprotein translocase YajC HW35_04945 09e31cbbdda282d1a6fc6d89f4133884 92 Pfam PF02699 Preprotein translocase subunit 6 81 3.9E-31 T 12-10-2018 IPR003849 Preprotein translocase YajC HW35_04945 09e31cbbdda282d1a6fc6d89f4133884 92 PRINTS PR01853 Bacterial YajC preprotein translocase signature 4 24 6.1E-16 T 12-10-2018 IPR003849 Preprotein translocase YajC HW35_04945 09e31cbbdda282d1a6fc6d89f4133884 92 PRINTS PR01853 Bacterial YajC preprotein translocase signature 24 42 6.1E-16 T 12-10-2018 IPR003849 Preprotein translocase YajC HW35_04945 09e31cbbdda282d1a6fc6d89f4133884 92 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 4 84 8.7E-33 T 12-10-2018 IPR003849 Preprotein translocase YajC HW35_07780 f41bde777c365d80e3bdb32b896e79ed 305 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 9 302 43.598 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 HW35_07780 f41bde777c365d80e3bdb32b896e79ed 305 Pfam PF04227 Indigoidine synthase A like protein 10 298 3.7E-133 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 HW35_07780 f41bde777c365d80e3bdb32b896e79ed 305 SUPERFAMILY SSF110581 3 300 5.89E-118 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 HW35_07780 f41bde777c365d80e3bdb32b896e79ed 305 Gene3D G3DSA:3.40.1790.10 1 305 1.5E-137 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 HW35_05415 7065a01b8a9e3a4602cbb4fb23b55790 253 Gene3D G3DSA:1.10.1060.10 114 248 3.2E-28 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HW35_05415 7065a01b8a9e3a4602cbb4fb23b55790 253 Pfam PF13237 4Fe-4S dicluster domain 149 223 6.8E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HW35_05415 7065a01b8a9e3a4602cbb4fb23b55790 253 SUPERFAMILY SSF46548 114 239 6.1E-27 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HW35_05415 7065a01b8a9e3a4602cbb4fb23b55790 253 SUPERFAMILY SSF54292 4 112 6.3E-24 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 HW35_05415 7065a01b8a9e3a4602cbb4fb23b55790 253 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 155 166 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_05415 7065a01b8a9e3a4602cbb4fb23b55790 253 Gene3D G3DSA:3.10.20.30 1 112 2.6E-33 T 12-10-2018 IPR012675 Beta-grasp domain superfamily HW35_05415 7065a01b8a9e3a4602cbb4fb23b55790 253 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 234 6.8E-43 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05415 7065a01b8a9e3a4602cbb4fb23b55790 253 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 117 2.7E-30 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_12980 670efc43f3c09f7b4b05a42e2007b372 208 Hamap MF_01969 Kynurenine formamidase [kynB]. 3 207 42.174 T 12-10-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 HW35_12980 670efc43f3c09f7b4b05a42e2007b372 208 SUPERFAMILY SSF102198 2 205 4.71E-58 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 HW35_12980 670efc43f3c09f7b4b05a42e2007b372 208 Gene3D G3DSA:3.50.30.50 1 207 7.1E-75 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 HW35_12980 670efc43f3c09f7b4b05a42e2007b372 208 TIGRFAM TIGR03035 trp_arylform: arylformamidase 3 207 8.9E-85 T 12-10-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 HW35_12980 670efc43f3c09f7b4b05a42e2007b372 208 Pfam PF04199 Putative cyclase 5 149 2.6E-21 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 HW35_16755 71fe7093e3af3a1c49a60aabc1f7817c 467 SMART SM00382 52 360 7.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_16755 71fe7093e3af3a1c49a60aabc1f7817c 467 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 361 429 8.0E-8 T 12-10-2018 IPR019489 Clp ATPase, C-terminal HW35_16755 71fe7093e3af3a1c49a60aabc1f7817c 467 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 4 467 44.509 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 HW35_16755 71fe7093e3af3a1c49a60aabc1f7817c 467 Pfam PF07724 AAA domain (Cdc48 subfamily) 215 353 5.5E-42 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_16755 71fe7093e3af3a1c49a60aabc1f7817c 467 SMART SM01086 359 455 2.6E-24 T 12-10-2018 IPR019489 Clp ATPase, C-terminal HW35_16755 71fe7093e3af3a1c49a60aabc1f7817c 467 SUPERFAMILY SSF52540 7 465 1.13E-93 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16755 71fe7093e3af3a1c49a60aabc1f7817c 467 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 7 467 5.3E-217 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 HW35_16755 71fe7093e3af3a1c49a60aabc1f7817c 467 Gene3D G3DSA:1.10.8.60 359 464 2.6E-41 T 12-10-2018 HW35_16755 71fe7093e3af3a1c49a60aabc1f7817c 467 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 56 139 4.3E-7 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_02520 1eda4e4b36f5c75780d354dfcb179e16 227 PRINTS PR00701 60kDa inner membrane protein signature 179 202 7.4E-7 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HW35_02520 1eda4e4b36f5c75780d354dfcb179e16 227 PRINTS PR00701 60kDa inner membrane protein signature 96 119 7.4E-7 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HW35_02520 1eda4e4b36f5c75780d354dfcb179e16 227 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 24 212 4.2E-56 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_02520 1eda4e4b36f5c75780d354dfcb179e16 227 Pfam PF02096 60Kd inner membrane protein 25 212 3.2E-49 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HW35_08615 4314135180ba4dd81c0a7e6fdf2efd0c 475 Gene3D G3DSA:3.40.50.10420 145 296 1.6E-12 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily HW35_08615 4314135180ba4dd81c0a7e6fdf2efd0c 475 SUPERFAMILY SSF46548 279 394 5.41E-19 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HW35_08615 4314135180ba4dd81c0a7e6fdf2efd0c 475 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 475 64.927 T 12-10-2018 IPR022825 Lactate utilization protein B HW35_08615 4314135180ba4dd81c0a7e6fdf2efd0c 475 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 314 325 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_08615 4314135180ba4dd81c0a7e6fdf2efd0c 475 SUPERFAMILY SSF100950 65 297 2.34E-39 T 12-10-2018 IPR037171 NagB/RpiA transferase-like HW35_08615 4314135180ba4dd81c0a7e6fdf2efd0c 475 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 456 3.9E-207 T 12-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 HW35_08615 4314135180ba4dd81c0a7e6fdf2efd0c 475 Pfam PF11870 Domain of unknown function (DUF3390) 385 472 6.1E-23 T 12-10-2018 IPR024569 4Fe-4S binding protein, C-terminal HW35_08615 4314135180ba4dd81c0a7e6fdf2efd0c 475 Pfam PF13183 4Fe-4S dicluster domain 312 378 5.3E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HW35_08615 4314135180ba4dd81c0a7e6fdf2efd0c 475 Pfam PF02589 LUD domain 71 296 2.9E-56 T 12-10-2018 IPR003741 LUD domain HW35_02145 652b969bc07ab23a894774d5baa7cde6 292 Pfam PF04294 VanW like protein 147 276 1.8E-50 T 12-10-2018 IPR007391 Vancomycin resistance VanW HW35_02145 652b969bc07ab23a894774d5baa7cde6 292 Pfam PF12229 Putative peptidoglycan binding domain 49 99 8.3E-6 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain HW35_10620 5287823cd0889b3aa336ecb022e97bb9 141 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 7 133 30.442 T 12-10-2018 IPR008226 Mini-ribonuclease 3 family HW35_10620 5287823cd0889b3aa336ecb022e97bb9 141 Gene3D G3DSA:1.10.1520.10 4 141 6.3E-50 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 HW35_10620 5287823cd0889b3aa336ecb022e97bb9 141 PIRSF PIRSF005520 1 138 1.2E-52 T 12-10-2018 IPR008226 Mini-ribonuclease 3 family HW35_10620 5287823cd0889b3aa336ecb022e97bb9 141 SUPERFAMILY SSF69065 9 131 4.71E-43 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 HW35_10620 5287823cd0889b3aa336ecb022e97bb9 141 SMART SM00535 1 137 8.1E-7 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 HW35_10620 5287823cd0889b3aa336ecb022e97bb9 141 Pfam PF00636 Ribonuclease III domain 17 116 4.0E-16 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 HW35_13820 f4f886f6d8d32ad3bee3092370a3831b 120 SUPERFAMILY SSF46785 10 100 4.62E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13820 f4f886f6d8d32ad3bee3092370a3831b 120 Gene3D G3DSA:1.10.10.10 1 113 3.0E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_13820 f4f886f6d8d32ad3bee3092370a3831b 120 Pfam PF03551 Transcriptional regulator PadR-like family 14 87 1.5E-27 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 SMART SM01185 67 121 5.7E-27 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 2.2E-82 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 3.6E-23 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 SUPERFAMILY SSF50249 65 129 2.14E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 Gene3D G3DSA:2.40.50.140 64 127 8.2E-27 T 12-10-2018 HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 SMART SM00841 129 184 1.1E-35 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 PIRSF PIRSF005901 1 185 3.8E-74 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 Gene3D G3DSA:2.40.50.140 128 185 3.7E-27 T 12-10-2018 HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 SUPERFAMILY SSF50249 128 185 3.08E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.0E-28 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 Gene3D G3DSA:2.30.30.30 1 62 1.8E-32 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 SUPERFAMILY SSF50104 1 63 1.26E-22 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 51.474 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 HW35_04060 5adbf426298f5cdc92142aaf6cd1f669 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 3.8E-27 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 HW35_17430 257e3808f4100ce3dc1f1e80f861a2ec 236 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 27 234 1.2E-92 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 HW35_17430 257e3808f4100ce3dc1f1e80f861a2ec 236 PIRSF PIRSF000857 6 236 4.4E-90 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 HW35_17430 257e3808f4100ce3dc1f1e80f861a2ec 236 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 45 233 3.8E-76 T 12-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 HW35_17430 257e3808f4100ce3dc1f1e80f861a2ec 236 SUPERFAMILY SSF52402 15 199 4.92E-52 T 12-10-2018 HW35_17430 257e3808f4100ce3dc1f1e80f861a2ec 236 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 4 235 40.538 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 HW35_17430 257e3808f4100ce3dc1f1e80f861a2ec 236 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 211 2.9E-52 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 HW35_17430 257e3808f4100ce3dc1f1e80f861a2ec 236 Gene3D G3DSA:3.40.50.620 3 236 1.2E-78 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_12110 765d754ad971e53b7cca18429f80e799 495 Gene3D G3DSA:3.40.50.300 1 244 5.1E-56 T 12-10-2018 HW35_12110 765d754ad971e53b7cca18429f80e799 495 Pfam PF00005 ABC transporter 271 424 7.1E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12110 765d754ad971e53b7cca18429f80e799 495 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_12110 765d754ad971e53b7cca18429f80e799 495 Gene3D G3DSA:3.40.50.300 252 491 1.7E-40 T 12-10-2018 HW35_12110 765d754ad971e53b7cca18429f80e799 495 SUPERFAMILY SSF52540 4 230 9.89E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12110 765d754ad971e53b7cca18429f80e799 495 SUPERFAMILY SSF52540 243 475 1.96E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12110 765d754ad971e53b7cca18429f80e799 495 Pfam PF00005 ABC transporter 20 169 1.0E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12110 765d754ad971e53b7cca18429f80e799 495 SMART SM00382 29 217 2.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_12110 765d754ad971e53b7cca18429f80e799 495 SMART SM00382 279 473 0.0089 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_08535 6d9dfff6a73b6892ee3566c2f9dd068f 785 Pfam PF05547 Immune inhibitor A peptidase M6 140 781 2.8E-273 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 HW35_08535 6d9dfff6a73b6892ee3566c2f9dd068f 785 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 175 483 5.7E-84 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 HW35_08535 6d9dfff6a73b6892ee3566c2f9dd068f 785 SUPERFAMILY SSF55486 274 423 7.1E-17 T 12-10-2018 HW35_08535 6d9dfff6a73b6892ee3566c2f9dd068f 785 PIRSF PIRSF007519 4 785 6.1E-304 T 12-10-2018 IPR012300 Peptidase M6, InhA HW35_04610 739c40685b1c21bf14c24e31197498e1 215 Gene3D G3DSA:1.10.150.280 147 215 9.4E-25 T 12-10-2018 HW35_04610 739c40685b1c21bf14c24e31197498e1 215 Gene3D G3DSA:3.10.560.10 57 129 5.3E-10 T 12-10-2018 HW35_04610 739c40685b1c21bf14c24e31197498e1 215 Pfam PF10531 SLBB domain 69 123 3.1E-11 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_04610 739c40685b1c21bf14c24e31197498e1 215 Pfam PF12836 Helix-hairpin-helix motif 150 213 7.0E-27 T 12-10-2018 HW35_04610 739c40685b1c21bf14c24e31197498e1 215 SUPERFAMILY SSF47781 148 214 7.89E-34 T 12-10-2018 IPR010994 RuvA domain 2-like HW35_04610 739c40685b1c21bf14c24e31197498e1 215 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 152 214 1.8E-25 T 12-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain HW35_04610 739c40685b1c21bf14c24e31197498e1 215 SMART SM00278 162 181 0.0028 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HW35_04610 739c40685b1c21bf14c24e31197498e1 215 SMART SM00278 192 211 0.024 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 Gene3D G3DSA:3.40.50.800 285 401 1.0E-33 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 105 272 2.6E-17 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 SUPERFAMILY SSF55681 14 278 4.98E-80 T 12-10-2018 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 SUPERFAMILY SSF52954 280 401 4.08E-34 T 12-10-2018 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 Pfam PF03129 Anticodon binding domain 291 381 2.8E-20 T 12-10-2018 IPR004154 Anticodon-binding HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 Gene3D G3DSA:3.30.110.30 403 476 9.9E-26 T 12-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 SUPERFAMILY SSF64586 406 476 3.92E-23 T 12-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 138 146 1.9E-9 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 67 85 1.9E-9 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 108 119 1.9E-9 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 147 158 1.9E-9 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 Hamap MF_01571 Proline--tRNA ligase [proS]. 9 476 44.7 T 12-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 410 476 3.0E-26 T 12-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 SMART SM00946 409 476 3.0E-35 T 12-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 12 476 7.5E-183 T 12-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 HW35_17645 d2835fadfa57797b06aa264e53d280d8 476 Gene3D G3DSA:3.30.930.10 5 284 3.6E-104 T 12-10-2018 HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.3E-104 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 Gene3D G3DSA:3.30.260.10 135 408 2.0E-236 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 Gene3D G3DSA:3.50.7.10 190 370 2.0E-236 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 SUPERFAMILY SSF48592 5 518 4.12E-81 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 SUPERFAMILY SSF54849 136 205 2.52E-26 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 7.9E-259 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 PRINTS PR00298 60kDa chaperonin signature 82 109 6.4E-73 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 PRINTS PR00298 60kDa chaperonin signature 26 52 6.4E-73 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 PRINTS PR00298 60kDa chaperonin signature 396 417 6.4E-73 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 PRINTS PR00298 60kDa chaperonin signature 348 373 6.4E-73 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 PRINTS PR00298 60kDa chaperonin signature 266 289 6.4E-73 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 SUPERFAMILY SSF52029 183 374 5.38E-85 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 541 42.433 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HW35_11585 d40be6cef322b6e1ed44332941073d3c 542 Gene3D G3DSA:1.10.560.10 7 518 2.0E-236 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily HW35_13010 ff3293cf734650c40991dadfdc8b8758 492 SUPERFAMILY SSF47203 264 481 1.09E-49 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 HW35_13010 ff3293cf734650c40991dadfdc8b8758 492 Gene3D G3DSA:2.40.110.10 146 274 2.2E-48 T 12-10-2018 HW35_13010 ff3293cf734650c40991dadfdc8b8758 492 Gene3D G3DSA:1.20.140.10 276 490 1.3E-60 T 12-10-2018 HW35_13010 ff3293cf734650c40991dadfdc8b8758 492 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 273 3.8E-99 T 12-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal HW35_13010 ff3293cf734650c40991dadfdc8b8758 492 SUPERFAMILY SSF56645 3 274 1.44E-87 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 HW35_13010 ff3293cf734650c40991dadfdc8b8758 492 Gene3D G3DSA:1.10.3140.10 2 145 1.9E-49 T 12-10-2018 HW35_13010 ff3293cf734650c40991dadfdc8b8758 492 PIRSF PIRSF000331 1 491 5.4E-167 T 12-10-2018 IPR004925 HpaB/PvcC/4-BUDH HW35_13010 ff3293cf734650c40991dadfdc8b8758 492 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 280 480 3.7E-50 T 12-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal HW35_05695 e29e52277a54c71f959038df367d0810 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 1.0E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05695 e29e52277a54c71f959038df367d0810 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 1.0E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05695 e29e52277a54c71f959038df367d0810 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 1.0E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05695 e29e52277a54c71f959038df367d0810 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 1.0E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05695 e29e52277a54c71f959038df367d0810 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 1.0E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05695 e29e52277a54c71f959038df367d0810 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 1.0E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05695 e29e52277a54c71f959038df367d0810 324 Gene3D G3DSA:3.90.226.10 2 316 1.0E-126 T 12-10-2018 HW35_05695 e29e52277a54c71f959038df367d0810 324 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 2.3E-66 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05695 e29e52277a54c71f959038df367d0810 324 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 3 315 1.4E-160 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05695 e29e52277a54c71f959038df367d0810 324 SUPERFAMILY SSF52096 6 315 5.55E-104 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_05695 e29e52277a54c71f959038df367d0810 324 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 50.66 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05940 06e790d36cc9cae003e68d4acc93d00f 154 Gene3D G3DSA:1.10.287.950 21 151 1.9E-5 T 12-10-2018 HW35_05940 06e790d36cc9cae003e68d4acc93d00f 154 SUPERFAMILY SSF58104 40 144 4.19E-6 T 12-10-2018 HW35_05940 06e790d36cc9cae003e68d4acc93d00f 154 Pfam PF06103 Bacterial protein of unknown function (DUF948) 8 94 9.9E-26 T 12-10-2018 IPR009293 Uncharacterised protein family UPF0478 HW35_11680 ce5958113bd5b254bd8d16bdc5cee21a 162 Gene3D G3DSA:3.40.50.7700 1 162 8.1E-75 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 HW35_11680 ce5958113bd5b254bd8d16bdc5cee21a 162 Pfam PF00731 AIR carboxylase 5 151 3.5E-67 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HW35_11680 ce5958113bd5b254bd8d16bdc5cee21a 162 SMART SM01001 3 154 1.7E-107 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HW35_11680 ce5958113bd5b254bd8d16bdc5cee21a 162 PIRSF PIRSF001338 1 162 3.7E-71 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 HW35_11680 ce5958113bd5b254bd8d16bdc5cee21a 162 SUPERFAMILY SSF52255 4 160 7.85E-70 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 HW35_11680 ce5958113bd5b254bd8d16bdc5cee21a 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 161 3.9E-70 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HW35_11680 ce5958113bd5b254bd8d16bdc5cee21a 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 34.087 T 12-10-2018 IPR033747 Class I PurE HW35_06165 8e3000d724e733fed167b8a1a766aa67 528 Gene3D G3DSA:2.170.8.10 38 330 1.0E-229 T 12-10-2018 HW35_06165 8e3000d724e733fed167b8a1a766aa67 528 PIRSF PIRSF006294 2 527 3.6E-249 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 HW35_06165 8e3000d724e733fed167b8a1a766aa67 528 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 2 526 2.6E-250 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 HW35_06165 8e3000d724e733fed167b8a1a766aa67 528 Pfam PF01293 Phosphoenolpyruvate carboxykinase 18 481 7.2E-231 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 HW35_06165 8e3000d724e733fed167b8a1a766aa67 528 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 528 57.085 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 HW35_06165 8e3000d724e733fed167b8a1a766aa67 528 Gene3D G3DSA:3.40.449.10 28 213 1.0E-229 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 HW35_06165 8e3000d724e733fed167b8a1a766aa67 528 Gene3D G3DSA:3.90.228.20 214 513 1.0E-229 T 12-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 HW35_06165 8e3000d724e733fed167b8a1a766aa67 528 SUPERFAMILY SSF68923 13 211 1.74E-82 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 HW35_06165 8e3000d724e733fed167b8a1a766aa67 528 SUPERFAMILY SSF53795 214 523 3.2E-137 T 12-10-2018 HW35_11955 b5d5f0c74868ce454d1b9dddaebc0485 210 Pfam PF02630 SCO1/SenC 14 188 2.8E-16 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_11955 b5d5f0c74868ce454d1b9dddaebc0485 210 Gene3D G3DSA:3.40.30.10 33 206 2.0E-38 T 12-10-2018 HW35_11955 b5d5f0c74868ce454d1b9dddaebc0485 210 SUPERFAMILY SSF52833 48 204 1.57E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 437 1.0E-137 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 PIRSF PIRSF000774 1 440 3.8E-132 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 Gene3D G3DSA:1.10.10.60 378 437 1.5E-23 T 12-10-2018 HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 7 51 2.7E-13 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 PRINTS PR00045 Sigma-54 factor signature 151 168 1.1E-24 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 PRINTS PR00045 Sigma-54 factor signature 353 364 1.1E-24 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 PRINTS PR00045 Sigma-54 factor signature 413 431 1.1E-24 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 PRINTS PR00045 Sigma-54 factor signature 337 349 1.1E-24 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 325 344 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 Gene3D G3DSA:1.10.10.1330 85 193 2.8E-25 T 12-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 Pfam PF04552 Sigma-54, DNA binding domain 278 438 4.9E-63 T 12-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 Pfam PF04963 Sigma-54 factor, core binding domain 78 265 2.4E-52 T 12-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 HW35_07430 1e6de5ec8f331bdbbb1b06f5014dccf0 440 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 418 425 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HW35_10045 0a0a027f04dddcb91da518daa42932af 452 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 30 284 6.9E-83 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HW35_10045 0a0a027f04dddcb91da518daa42932af 452 SUPERFAMILY SSF69189 303 398 1.16E-13 T 12-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_10045 0a0a027f04dddcb91da518daa42932af 452 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 320 422 1.5E-14 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_10045 0a0a027f04dddcb91da518daa42932af 452 Gene3D G3DSA:3.40.710.10 28 311 9.6E-88 T 12-10-2018 HW35_10045 0a0a027f04dddcb91da518daa42932af 452 SUPERFAMILY SSF56601 11 310 2.13E-76 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_10045 0a0a027f04dddcb91da518daa42932af 452 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 4.2E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_10045 0a0a027f04dddcb91da518daa42932af 452 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 122 139 4.2E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_10045 0a0a027f04dddcb91da518daa42932af 452 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 149 162 4.2E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_10045 0a0a027f04dddcb91da518daa42932af 452 Gene3D G3DSA:2.60.410.10 312 422 5.5E-16 T 12-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_10045 0a0a027f04dddcb91da518daa42932af 452 SMART SM00936 321 422 1.2E-12 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Gene3D G3DSA:3.40.50.1380 939 1067 5.1E-26 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Gene3D G3DSA:3.30.470.20 662 932 8.3E-89 T 12-10-2018 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 SUPERFAMILY SSF52440 1 127 3.6E-49 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.2E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.2E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.2E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.2E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 2.2E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.2E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 2.2E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Pfam PF02142 MGS-like domain 961 1036 3.0E-13 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 SUPERFAMILY SSF56059 128 399 1.48E-111 T 12-10-2018 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Gene3D G3DSA:3.40.50.20 550 658 1.8E-47 T 12-10-2018 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 SUPERFAMILY SSF56059 669 932 2.83E-86 T 12-10-2018 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 12.615 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 SMART SM00851 953 1036 7.7E-9 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 835 842 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 543 3.8E-38 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 SUPERFAMILY SSF48108 395 549 1.22E-46 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 SMART SM01096 420 543 2.4E-55 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Gene3D G3DSA:3.30.470.20 119 401 5.4E-128 T 12-10-2018 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 4 1046 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 SUPERFAMILY SSF52335 941 1065 5.23E-18 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Gene3D G3DSA:3.40.50.20 1 116 3.9E-47 T 12-10-2018 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 SUPERFAMILY SSF52440 552 671 6.91E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Gene3D G3DSA:1.10.1030.10 404 549 1.1E-42 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 2.3E-80 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_14150 d43715330f6306dc0c59214612ba8dd6 1077 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 871 2.5E-35 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16680 b66cc4bfb43a72b57fd57566acbe0e64 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.087 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16680 b66cc4bfb43a72b57fd57566acbe0e64 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 6.0E-36 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16680 b66cc4bfb43a72b57fd57566acbe0e64 90 SUPERFAMILY SSF54565 2 86 4.32E-35 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16680 b66cc4bfb43a72b57fd57566acbe0e64 90 Gene3D G3DSA:3.30.1320.10 1 90 6.5E-38 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16680 b66cc4bfb43a72b57fd57566acbe0e64 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 12-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16680 b66cc4bfb43a72b57fd57566acbe0e64 90 Pfam PF00886 Ribosomal protein S16 9 67 2.4E-26 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_02515 e624df7ebb4aedb8dff32508c1b597d3 249 Pfam PF13353 4Fe-4S single cluster domain 14 144 1.2E-21 T 12-10-2018 HW35_02515 e624df7ebb4aedb8dff32508c1b597d3 249 PIRSF PIRSF000371 1 45 6.5E-12 T 12-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 HW35_02515 e624df7ebb4aedb8dff32508c1b597d3 249 PIRSF PIRSF000371 43 245 7.6E-47 T 12-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 HW35_02515 e624df7ebb4aedb8dff32508c1b597d3 249 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 4 241 1.9E-97 T 12-10-2018 IPR012838 Pyruvate formate-lyase 1 activating enzyme GO:0043365|GO:0055114 HW35_02515 e624df7ebb4aedb8dff32508c1b597d3 249 SUPERFAMILY SSF102114 20 221 5.49E-25 T 12-10-2018 HW35_02515 e624df7ebb4aedb8dff32508c1b597d3 249 ProSitePatterns PS01087 Radical activating enzymes signature. 16 37 - T 12-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 HW35_02515 e624df7ebb4aedb8dff32508c1b597d3 249 Gene3D G3DSA:3.20.20.70 1 245 1.2E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_02515 e624df7ebb4aedb8dff32508c1b597d3 249 Pfam PF04055 Radical SAM superfamily 22 182 3.1E-27 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_06185 2d752b14b1397ec08ef188ae172d3dc0 265 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_06185 2d752b14b1397ec08ef188ae172d3dc0 265 SUPERFAMILY SSF52540 4 220 4.82E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_06185 2d752b14b1397ec08ef188ae172d3dc0 265 SMART SM00382 32 212 1.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_06185 2d752b14b1397ec08ef188ae172d3dc0 265 Pfam PF00005 ABC transporter 23 163 3.9E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_06185 2d752b14b1397ec08ef188ae172d3dc0 265 Gene3D G3DSA:3.40.50.300 2 264 1.6E-62 T 12-10-2018 HW35_03105 7250675afb0be07b7e861f060573e99c 767 Pfam PF00270 DEAD/DEAH box helicase 63 232 9.9E-30 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HW35_03105 7250675afb0be07b7e861f060573e99c 767 SUPERFAMILY SSF52540 74 450 2.16E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03105 7250675afb0be07b7e861f060573e99c 767 SMART SM00490 307 394 7.5E-13 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_03105 7250675afb0be07b7e861f060573e99c 767 Gene3D G3DSA:3.40.50.300 273 435 4.7E-21 T 12-10-2018 HW35_03105 7250675afb0be07b7e861f060573e99c 767 Pfam PF00271 Helicase conserved C-terminal domain 289 393 4.1E-13 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_03105 7250675afb0be07b7e861f060573e99c 767 Gene3D G3DSA:3.40.50.300 32 250 3.6E-48 T 12-10-2018 HW35_03105 7250675afb0be07b7e861f060573e99c 767 SMART SM00487 56 260 2.0E-32 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_03105 7250675afb0be07b7e861f060573e99c 767 Pfam PF09369 Domain of unknown function (DUF1998) 654 733 6.1E-23 T 12-10-2018 IPR018973 DEAD/DEAH-box helicase, putative HW35_03105 7250675afb0be07b7e861f060573e99c 767 SUPERFAMILY SSF52540 43 240 2.1E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05190 3aba312dfceae08537689202e78e4d2c 350 TIGRFAM TIGR02904 spore_ysxE: spore coat protein YsxE 11 315 2.2E-106 T 12-10-2018 IPR014253 Spore coat protein YsxE HW35_05190 3aba312dfceae08537689202e78e4d2c 350 SUPERFAMILY SSF56112 7 316 2.92E-19 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_05190 3aba312dfceae08537689202e78e4d2c 350 Gene3D G3DSA:3.30.200.20 2 94 7.1E-13 T 12-10-2018 HW35_05190 3aba312dfceae08537689202e78e4d2c 350 Pfam PF02958 Ecdysteroid kinase 95 266 5.6E-7 T 12-10-2018 IPR004119 Protein of unknown function DUF227 HW35_05190 3aba312dfceae08537689202e78e4d2c 350 Gene3D G3DSA:3.90.1200.10 96 320 1.9E-22 T 12-10-2018 HW35_08955 57e8ae9830f7cb3a5132b7c8c20dd12e 144 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 35.943 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HW35_08955 57e8ae9830f7cb3a5132b7c8c20dd12e 144 SUPERFAMILY SSF54637 1 138 2.34E-49 T 12-10-2018 IPR029069 HotDog domain superfamily HW35_08955 57e8ae9830f7cb3a5132b7c8c20dd12e 144 Gene3D G3DSA:3.10.129.10 1 144 4.0E-62 T 12-10-2018 HW35_08955 57e8ae9830f7cb3a5132b7c8c20dd12e 144 Pfam PF07977 FabA-like domain 11 134 1.4E-37 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HW35_08955 57e8ae9830f7cb3a5132b7c8c20dd12e 144 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 3.8E-60 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HW35_10780 cdc297269dd3b8d0c6288ed67399a6d9 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 12-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10780 cdc297269dd3b8d0c6288ed67399a6d9 61 Pfam PF00253 Ribosomal protein S14p/S29e 10 60 9.5E-25 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10780 cdc297269dd3b8d0c6288ed67399a6d9 61 SUPERFAMILY SSF57716 3 61 3.14E-22 T 12-10-2018 HW35_10780 cdc297269dd3b8d0c6288ed67399a6d9 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.091 T 12-10-2018 IPR023053 Ribosomal protein S14, type Z HW35_10780 cdc297269dd3b8d0c6288ed67399a6d9 61 Gene3D G3DSA:4.10.830.10 1 61 9.0E-31 T 12-10-2018 HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 SUPERFAMILY SSF52518 342 527 8.77E-70 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 SUPERFAMILY SSF52922 532 667 4.06E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 Pfam PF02780 Transketolase, C-terminal domain 550 658 2.5E-10 T 12-10-2018 IPR033248 Transketolase, C-terminal domain HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 666 0.0 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 339 7.0E-154 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 Gene3D G3DSA:3.40.50.970 4 331 5.3E-129 T 12-10-2018 HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 SUPERFAMILY SSF52518 7 326 3.85E-119 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 Pfam PF02779 Transketolase, pyrimidine binding domain 354 525 7.1E-46 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 Gene3D G3DSA:3.40.50.970 332 539 2.3E-79 T 12-10-2018 HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 Gene3D G3DSA:3.40.50.920 541 667 5.7E-42 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HW35_17200 27a6bd76a94784fe4e1b06fac5311eea 668 SMART SM00861 355 526 1.5E-70 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HW35_00300 c08593ce8bd5a343cb0fa4171f3ba150 93 Gene3D G3DSA:1.10.10.60 9 87 2.8E-9 T 12-10-2018 HW35_00300 c08593ce8bd5a343cb0fa4171f3ba150 93 Pfam PF01527 Transposase 3 73 6.8E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_00300 c08593ce8bd5a343cb0fa4171f3ba150 93 SUPERFAMILY SSF46689 5 90 4.78E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_02220 c08593ce8bd5a343cb0fa4171f3ba150 93 Gene3D G3DSA:1.10.10.60 9 87 2.8E-9 T 12-10-2018 HW35_02220 c08593ce8bd5a343cb0fa4171f3ba150 93 Pfam PF01527 Transposase 3 73 6.8E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_02220 c08593ce8bd5a343cb0fa4171f3ba150 93 SUPERFAMILY SSF46689 5 90 4.78E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_09930 aec369d2d255e300019c943757080901 287 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 32 285 7.2E-115 T 12-10-2018 IPR023705 Nucleoid occlusion protein HW35_09930 aec369d2d255e300019c943757080901 287 SUPERFAMILY SSF109709 118 224 2.14E-35 T 12-10-2018 HW35_09930 aec369d2d255e300019c943757080901 287 Pfam PF02195 ParB-like nuclease domain 35 123 4.5E-29 T 12-10-2018 IPR003115 ParB/Sulfiredoxin HW35_09930 aec369d2d255e300019c943757080901 287 Gene3D G3DSA:3.90.1530.30 47 110 4.5E-25 T 12-10-2018 HW35_09930 aec369d2d255e300019c943757080901 287 Hamap MF_02015 Nucleoid occlusion protein [noc]. 3 285 37.748 T 12-10-2018 IPR023705 Nucleoid occlusion protein HW35_09930 aec369d2d255e300019c943757080901 287 Gene3D G3DSA:1.10.10.2830 111 225 3.0E-37 T 12-10-2018 HW35_09930 aec369d2d255e300019c943757080901 287 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 32 209 7.7E-63 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 HW35_09930 aec369d2d255e300019c943757080901 287 SUPERFAMILY SSF110849 34 126 2.01E-29 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily HW35_09930 aec369d2d255e300019c943757080901 287 SMART SM00470 34 124 1.8E-38 T 12-10-2018 IPR003115 ParB/Sulfiredoxin HW35_15405 59a365ed956e22d71fe69465700115e0 623 SUPERFAMILY SSF116726 540 614 1.83E-11 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_15405 59a365ed956e22d71fe69465700115e0 623 Gene3D G3DSA:3.40.50.720 404 533 1.5E-9 T 12-10-2018 HW35_15405 59a365ed956e22d71fe69465700115e0 623 Pfam PF02080 TrkA-C domain 549 613 1.1E-11 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HW35_15405 59a365ed956e22d71fe69465700115e0 623 Pfam PF00999 Sodium/hydrogen exchanger family 11 389 2.3E-71 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 HW35_15405 59a365ed956e22d71fe69465700115e0 623 Pfam PF02254 TrkA-N domain 405 515 1.4E-6 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HW35_15405 59a365ed956e22d71fe69465700115e0 623 Gene3D G3DSA:3.30.70.1450 534 616 7.1E-21 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_15405 59a365ed956e22d71fe69465700115e0 623 SUPERFAMILY SSF51735 405 517 6.89E-8 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_15405 59a365ed956e22d71fe69465700115e0 623 Gene3D G3DSA:1.20.1530.20 4 401 4.8E-69 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily HW35_08530 54ac1c8781586b46b2c7c182c748f05e 364 Pfam PF12698 ABC-2 family transporter protein 15 351 3.5E-44 T 12-10-2018 HW35_08530 54ac1c8781586b46b2c7c182c748f05e 364 PRINTS PR00164 ABC-2 type transport system membrane protein signature 243 267 2.1E-10 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HW35_08530 54ac1c8781586b46b2c7c182c748f05e 364 PRINTS PR00164 ABC-2 type transport system membrane protein signature 280 299 2.1E-10 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HW35_08530 54ac1c8781586b46b2c7c182c748f05e 364 PRINTS PR00164 ABC-2 type transport system membrane protein signature 162 184 2.1E-10 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HW35_07495 67e5655516535bccf46df4a1d2c046dd 282 Gene3D G3DSA:3.40.50.720 3 266 1.9E-101 T 12-10-2018 HW35_07495 67e5655516535bccf46df4a1d2c046dd 282 Gene3D G3DSA:3.90.25.10 159 272 1.9E-101 T 12-10-2018 HW35_07495 67e5655516535bccf46df4a1d2c046dd 282 Pfam PF04321 RmlD substrate binding domain 1 279 1.9E-94 T 12-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 HW35_07495 67e5655516535bccf46df4a1d2c046dd 282 SUPERFAMILY SSF51735 1 278 8.67E-91 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_07495 67e5655516535bccf46df4a1d2c046dd 282 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 278 1.0E-90 T 12-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 HW35_00755 4278bb53a7e73c3894d40be346086339 70 Pfam PF09388 Spo0E like sporulation regulatory protein 7 48 4.9E-14 T 12-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 HW35_00755 4278bb53a7e73c3894d40be346086339 70 Gene3D G3DSA:1.20.58.990 3 65 4.4E-12 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 HW35_00755 4278bb53a7e73c3894d40be346086339 70 SUPERFAMILY SSF140500 5 54 1.22E-13 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 HW35_06805 d07d8ec6ef88267ff70e05ac28c0bfb6 387 SUPERFAMILY SSF56796 2 385 4.71E-118 T 12-10-2018 HW35_06805 d07d8ec6ef88267ff70e05ac28c0bfb6 387 Gene3D G3DSA:3.40.50.1970 1 184 4.0E-54 T 12-10-2018 HW35_06805 d07d8ec6ef88267ff70e05ac28c0bfb6 387 Gene3D G3DSA:1.20.1090.10 185 386 7.6E-49 T 12-10-2018 HW35_06805 d07d8ec6ef88267ff70e05ac28c0bfb6 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HW35_06805 d07d8ec6ef88267ff70e05ac28c0bfb6 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HW35_06805 d07d8ec6ef88267ff70e05ac28c0bfb6 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 375 5.0E-102 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 HW35_08890 8b6f3d89bc121067cf559cfb0b417a40 546 Pfam PF04434 SWIM zinc finger 74 97 1.2E-4 T 12-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 HW35_03125 ddde95670422c2002ae95263c01c149f 70 Pfam PF14178 YppF-like protein 1 58 4.8E-24 T 12-10-2018 IPR025553 YppF-like protein HW35_03125 ddde95670422c2002ae95263c01c149f 70 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 59 2.0E-6 T 12-10-2018 HW35_04380 410e42f0dcc111b9083a5cb55174130f 435 Gene3D G3DSA:3.40.50.300 1 217 3.4E-68 T 12-10-2018 HW35_04380 410e42f0dcc111b9083a5cb55174130f 435 Gene3D G3DSA:3.40.50.300 218 435 6.1E-46 T 12-10-2018 HW35_04380 410e42f0dcc111b9083a5cb55174130f 435 Pfam PF00270 DEAD/DEAH box helicase 26 194 7.1E-43 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HW35_04380 410e42f0dcc111b9083a5cb55174130f 435 SMART SM00490 258 339 4.3E-29 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_04380 410e42f0dcc111b9083a5cb55174130f 435 SMART SM00487 21 222 2.1E-50 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_04380 410e42f0dcc111b9083a5cb55174130f 435 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 2 435 50.03 T 12-10-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 HW35_04380 410e42f0dcc111b9083a5cb55174130f 435 Pfam PF00271 Helicase conserved C-terminal domain 231 339 2.2E-27 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_04380 410e42f0dcc111b9083a5cb55174130f 435 SUPERFAMILY SSF52540 70 360 4.84E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10375 18d316af2ee25dd389a1cc09e713bf22 295 Pfam PF13624 SurA N-terminal domain 12 128 1.0E-6 T 12-10-2018 HW35_10375 18d316af2ee25dd389a1cc09e713bf22 295 Gene3D G3DSA:1.10.4030.30 38 250 5.8E-31 T 12-10-2018 HW35_10375 18d316af2ee25dd389a1cc09e713bf22 295 Pfam PF13145 PPIC-type PPIASE domain 136 260 1.6E-19 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 HW35_10375 18d316af2ee25dd389a1cc09e713bf22 295 Gene3D G3DSA:3.10.50.40 156 249 5.8E-31 T 12-10-2018 HW35_10375 18d316af2ee25dd389a1cc09e713bf22 295 SUPERFAMILY SSF109998 38 184 1.7E-25 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily HW35_10375 18d316af2ee25dd389a1cc09e713bf22 295 SUPERFAMILY SSF54534 148 246 2.49E-20 T 12-10-2018 HW35_10375 18d316af2ee25dd389a1cc09e713bf22 295 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 184 205 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 HW35_14955 456471f1337108dd99243fbeb90c3515 238 Pfam PF12787 EcsC protein family 8 234 1.0E-77 T 12-10-2018 IPR024787 EcsC protein HW35_14955 456471f1337108dd99243fbeb90c3515 238 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 1 234 4.0E-76 T 12-10-2018 HW35_01225 98ecdf7583708bbfc7690af3fcf4af8a 297 Pfam PF03466 LysR substrate binding domain 90 292 4.5E-45 T 12-10-2018 IPR005119 LysR, substrate-binding HW35_01225 98ecdf7583708bbfc7690af3fcf4af8a 297 Gene3D G3DSA:3.40.190.290 91 295 2.1E-42 T 12-10-2018 HW35_01225 98ecdf7583708bbfc7690af3fcf4af8a 297 Gene3D G3DSA:1.10.10.10 1 90 4.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_01225 98ecdf7583708bbfc7690af3fcf4af8a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_01225 98ecdf7583708bbfc7690af3fcf4af8a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_01225 98ecdf7583708bbfc7690af3fcf4af8a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_01225 98ecdf7583708bbfc7690af3fcf4af8a 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 9.8E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_01225 98ecdf7583708bbfc7690af3fcf4af8a 297 SUPERFAMILY SSF46785 2 85 4.47E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_01225 98ecdf7583708bbfc7690af3fcf4af8a 297 SUPERFAMILY SSF53850 90 295 1.13E-40 T 12-10-2018 HW35_00440 e3305c2711e75e35d3f74791105db68e 122 Gene3D G3DSA:1.20.120.340 1 122 3.6E-35 T 12-10-2018 HW35_00440 e3305c2711e75e35d3f74791105db68e 122 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 119 8.5E-33 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 HW35_00440 e3305c2711e75e35d3f74791105db68e 122 Pfam PF02561 Flagellar protein FliS 7 118 4.7E-34 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 HW35_00440 e3305c2711e75e35d3f74791105db68e 122 SUPERFAMILY SSF101116 4 121 1.19E-33 T 12-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 HW35_00440 e3305c2711e75e35d3f74791105db68e 122 PIRSF PIRSF039090 1 122 5.3E-29 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 HW35_12975 407a2f02766d11bbc8642ff1d2fd80b8 354 SUPERFAMILY SSF53756 4 345 1.47E-93 T 12-10-2018 HW35_12975 407a2f02766d11bbc8642ff1d2fd80b8 354 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 348 5.1E-82 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_12975 407a2f02766d11bbc8642ff1d2fd80b8 354 Gene3D G3DSA:3.40.50.2000 177 340 8.6E-40 T 12-10-2018 HW35_12975 407a2f02766d11bbc8642ff1d2fd80b8 354 Gene3D G3DSA:3.40.50.2000 2 176 7.3E-61 T 12-10-2018 HW35_12975 407a2f02766d11bbc8642ff1d2fd80b8 354 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 354 29.752 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_12975 407a2f02766d11bbc8642ff1d2fd80b8 354 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 342 4.8E-33 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 HW35_12975 407a2f02766d11bbc8642ff1d2fd80b8 354 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 142 4.8E-42 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_00255 2df856f26672ed73753cf6e593d5cea0 161 Pfam PF01584 CheW-like domain 12 145 1.7E-32 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HW35_00255 2df856f26672ed73753cf6e593d5cea0 161 SMART SM00260 7 143 1.1E-29 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HW35_00255 2df856f26672ed73753cf6e593d5cea0 161 Gene3D G3DSA:2.40.50.180 28 143 1.7E-33 T 12-10-2018 HW35_00255 2df856f26672ed73753cf6e593d5cea0 161 SUPERFAMILY SSF50341 6 144 7.98E-34 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 HW35_00255 2df856f26672ed73753cf6e593d5cea0 161 Gene3D G3DSA:2.30.30.40 13 137 1.7E-33 T 12-10-2018 HW35_08035 85d46b4520ba0ff95de861f8c2861ec0 230 SUPERFAMILY SSF53448 1 226 1.1E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_08035 85d46b4520ba0ff95de861f8c2861ec0 230 Gene3D G3DSA:3.90.550.10 1 227 3.6E-59 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_08035 85d46b4520ba0ff95de861f8c2861ec0 230 PIRSF PIRSF037382 1 230 1.9E-92 T 12-10-2018 IPR017189 CTP:phosphocholine cytidylyltransferase HW35_08035 85d46b4520ba0ff95de861f8c2861ec0 230 Pfam PF00483 Nucleotidyl transferase 3 118 1.6E-12 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HW35_14555 dbb01f4190a797f5cc316409e15ae23c 223 SMART SM00873 62 212 1.5E-8 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HW35_14555 dbb01f4190a797f5cc316409e15ae23c 223 SUPERFAMILY SSF56037 52 218 7.06E-30 T 12-10-2018 HW35_14555 dbb01f4190a797f5cc316409e15ae23c 223 Gene3D G3DSA:3.50.40.10 73 199 6.2E-8 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 HW35_14555 dbb01f4190a797f5cc316409e15ae23c 223 Pfam PF03483 B3/4 domain 64 187 3.8E-20 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 Hamap MF_00268 Protein RecA [recA]. 4 328 53.694 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 323 8.1E-178 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 Gene3D G3DSA:3.30.250.10 267 342 7.8E-30 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal HW35_16990 9528908b8e66df00aa188da9feb0a242 346 PRINTS PR00142 RecA protein signature 209 237 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 PRINTS PR00142 RecA protein signature 242 271 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 PRINTS PR00142 RecA protein signature 92 121 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 PRINTS PR00142 RecA protein signature 164 193 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 PRINTS PR00142 RecA protein signature 126 155 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 PRINTS PR00142 RecA protein signature 296 313 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 Gene3D G3DSA:3.40.50.300 25 266 3.5E-83 T 12-10-2018 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 SMART SM00382 56 227 9.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_16990 9528908b8e66df00aa188da9feb0a242 346 SUPERFAMILY SSF54752 267 326 5.1E-23 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal HW35_16990 9528908b8e66df00aa188da9feb0a242 346 ProSitePatterns PS00321 recA signature. 212 220 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 Pfam PF00154 recA bacterial DNA recombination protein 7 267 9.0E-147 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HW35_16990 9528908b8e66df00aa188da9feb0a242 346 SUPERFAMILY SSF52540 3 266 1.42E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07255 c0260d46bcc6ab6189bbcc7eb3621953 273 Gene3D G3DSA:3.40.50.620 1 273 4.8E-83 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_07255 c0260d46bcc6ab6189bbcc7eb3621953 273 SUPERFAMILY SSF52402 3 272 6.4E-81 T 12-10-2018 HW35_07255 c0260d46bcc6ab6189bbcc7eb3621953 273 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 273 3.5E-75 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 HW35_07255 c0260d46bcc6ab6189bbcc7eb3621953 273 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 18 267 49.22 T 12-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 HW35_07255 c0260d46bcc6ab6189bbcc7eb3621953 273 Pfam PF02540 NAD synthase 23 264 4.6E-70 T 12-10-2018 IPR022310 NAD/GMP synthase HW35_07520 98952a5c3dfa41b18d9fbd488e1bb71d 166 SUPERFAMILY SSF53056 4 163 1.57E-14 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 HW35_07520 98952a5c3dfa41b18d9fbd488e1bb71d 166 Gene3D G3DSA:3.40.1050.10 1 163 7.7E-12 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 HW35_16510 7cf3ed04ebcf51addce3b0aef696c330 570 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 442 1.1E-161 T 12-10-2018 HW35_16510 7cf3ed04ebcf51addce3b0aef696c330 570 Pfam PF05670 Domain of unknown function (DUF814) 453 538 2.9E-29 T 12-10-2018 IPR008532 Domain of unknown function DUF814 HW35_16510 7cf3ed04ebcf51addce3b0aef696c330 570 Gene3D G3DSA:3.40.970.40 243 289 2.3E-18 T 12-10-2018 HW35_16510 7cf3ed04ebcf51addce3b0aef696c330 570 Gene3D G3DSA:2.30.310.10 1 167 4.3E-67 T 12-10-2018 HW35_16510 7cf3ed04ebcf51addce3b0aef696c330 570 Gene3D G3DSA:1.10.8.50 168 237 1.1E-22 T 12-10-2018 HW35_06870 906ae1cf756f919628a2e703188763a5 244 PIRSF PIRSF001467 167 244 2.1E-12 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 HW35_06870 906ae1cf756f919628a2e703188763a5 244 PIRSF PIRSF001467 46 177 8.2E-42 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 HW35_06870 906ae1cf756f919628a2e703188763a5 244 SUPERFAMILY SSF50891 64 243 1.61E-61 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily HW35_06870 906ae1cf756f919628a2e703188763a5 244 Gene3D G3DSA:2.40.100.10 33 180 8.4E-50 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily HW35_06870 906ae1cf756f919628a2e703188763a5 244 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 65 241 2.4E-52 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_06870 906ae1cf756f919628a2e703188763a5 244 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 189 201 1.8E-17 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_06870 906ae1cf756f919628a2e703188763a5 244 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 104 116 1.8E-17 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_06870 906ae1cf756f919628a2e703188763a5 244 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 78 93 1.8E-17 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_06870 906ae1cf756f919628a2e703188763a5 244 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 202 217 1.8E-17 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_06870 906ae1cf756f919628a2e703188763a5 244 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 99 116 - T 12-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 HW35_06870 906ae1cf756f919628a2e703188763a5 244 Gene3D G3DSA:2.40.100.10 188 244 2.9E-15 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily HW35_14975 f7db064565f70a155559806cc25b329f 348 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 140 156 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 HW35_14975 f7db064565f70a155559806cc25b329f 348 SUPERFAMILY SSF51726 4 343 1.44E-106 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HW35_14975 f7db064565f70a155559806cc25b329f 348 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 341 6.7E-125 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 HW35_14975 f7db064565f70a155559806cc25b329f 348 Gene3D G3DSA:3.20.20.210 1 348 8.1E-149 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HW35_14975 f7db064565f70a155559806cc25b329f 348 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 342 47.768 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 HW35_14975 f7db064565f70a155559806cc25b329f 348 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 8 340 6.0E-129 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 HW35_14975 f7db064565f70a155559806cc25b329f 348 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 HW35_16215 d568aa8a32482e92465a53d36ff1cda9 340 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 198 330 1.1E-11 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 HW35_16215 d568aa8a32482e92465a53d36ff1cda9 340 SMART SM00228 119 186 1.3E-8 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_16215 d568aa8a32482e92465a53d36ff1cda9 340 Pfam PF13180 PDZ domain 128 195 5.9E-15 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_16215 d568aa8a32482e92465a53d36ff1cda9 340 Gene3D G3DSA:2.30.42.10 128 205 1.2E-25 T 12-10-2018 HW35_16215 d568aa8a32482e92465a53d36ff1cda9 340 SUPERFAMILY SSF54211 229 333 1.02E-21 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_16215 d568aa8a32482e92465a53d36ff1cda9 340 SUPERFAMILY SSF50156 128 215 2.89E-18 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 HW35_16215 d568aa8a32482e92465a53d36ff1cda9 340 Gene3D G3DSA:3.30.230.10 206 340 4.4E-19 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_12125 cf3e9c74bdb8264d03e9d39b0b1a3834 299 SMART SM00382 26 204 7.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_12125 cf3e9c74bdb8264d03e9d39b0b1a3834 299 Pfam PF00005 ABC transporter 18 154 1.6E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12125 cf3e9c74bdb8264d03e9d39b0b1a3834 299 Gene3D G3DSA:3.40.50.300 1 228 7.0E-52 T 12-10-2018 HW35_12125 cf3e9c74bdb8264d03e9d39b0b1a3834 299 SUPERFAMILY SSF52540 2 226 6.43E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02885 b43bf76d7dfed65f1d8f2e0057e05ac0 259 SUPERFAMILY SSF103473 30 244 2.22E-5 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_02885 b43bf76d7dfed65f1d8f2e0057e05ac0 259 Pfam PF03741 Integral membrane protein TerC family 35 219 8.4E-54 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 HW35_02885 b43bf76d7dfed65f1d8f2e0057e05ac0 259 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 32 244 7.2E-79 T 12-10-2018 IPR022493 Integral membrane YkoY HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 SUPERFAMILY SSF53732 3 467 7.32E-174 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 466 3.6E-247 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 Pfam PF00330 Aconitase family (aconitate hydratase) 9 458 1.1E-164 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 PRINTS PR00415 Aconitase family signature 287 301 2.6E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 PRINTS PR00415 Aconitase family signature 109 117 2.6E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 PRINTS PR00415 Aconitase family signature 210 223 2.6E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 PRINTS PR00415 Aconitase family signature 196 209 2.6E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 PRINTS PR00415 Aconitase family signature 83 96 2.6E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 PRINTS PR00415 Aconitase family signature 134 149 2.6E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 PRINTS PR00415 Aconitase family signature 120 133 2.6E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 PRINTS PR00415 Aconitase family signature 344 355 2.6E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 PRINTS PR00415 Aconitase family signature 400 413 2.6E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 Gene3D G3DSA:3.30.499.20 6 287 4.2E-105 T 12-10-2018 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 467 59.439 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 HW35_13280 8849bf7c71f05d97fcfbe2665a3a828c 472 Gene3D G3DSA:3.30.499.10 329 471 8.2E-51 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 HW35_05850 6f84d1e8091f0bc2944b3fd601560274 402 Pfam PF02926 THUMP domain 41 162 1.1E-23 T 12-10-2018 IPR004114 THUMP domain GO:0003723 HW35_05850 6f84d1e8091f0bc2944b3fd601560274 402 SMART SM00981 74 165 2.0E-26 T 12-10-2018 IPR004114 THUMP domain GO:0003723 HW35_05850 6f84d1e8091f0bc2944b3fd601560274 402 SUPERFAMILY SSF52402 174 388 2.09E-52 T 12-10-2018 HW35_05850 6f84d1e8091f0bc2944b3fd601560274 402 Gene3D G3DSA:3.40.50.620 175 401 2.6E-74 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_05850 6f84d1e8091f0bc2944b3fd601560274 402 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 371 3.6E-67 T 12-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 HW35_05850 6f84d1e8091f0bc2944b3fd601560274 402 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 373 1.7E-132 T 12-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 HW35_05850 6f84d1e8091f0bc2944b3fd601560274 402 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 402 168.417 T 12-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 HW35_05850 6f84d1e8091f0bc2944b3fd601560274 402 Gene3D G3DSA:3.30.2130.30 1 174 1.8E-62 T 12-10-2018 HW35_05850 6f84d1e8091f0bc2944b3fd601560274 402 SUPERFAMILY SSF143437 3 173 2.27E-55 T 12-10-2018 HW35_17125 079a331dce0a80294e7c611c9650be02 631 SUPERFAMILY SSF55874 3 213 6.02E-53 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_17125 079a331dce0a80294e7c611c9650be02 631 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 4.4E-36 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 HW35_17125 079a331dce0a80294e7c611c9650be02 631 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 1.1E-101 T 12-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 HW35_17125 079a331dce0a80294e7c611c9650be02 631 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 627 28.324 T 12-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 HW35_17125 079a331dce0a80294e7c611c9650be02 631 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 84 3.7E-10 T 12-10-2018 HW35_17125 079a331dce0a80294e7c611c9650be02 631 SUPERFAMILY SSF54211 189 326 2.92E-37 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_17125 079a331dce0a80294e7c611c9650be02 631 Gene3D G3DSA:3.30.1370.100 487 580 6.1E-64 T 12-10-2018 HW35_17125 079a331dce0a80294e7c611c9650be02 631 SMART SM00853 445 587 1.3E-53 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 HW35_17125 079a331dce0a80294e7c611c9650be02 631 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 12-10-2018 IPR014762 DNA mismatch repair, conserved site HW35_17125 079a331dce0a80294e7c611c9650be02 631 Gene3D G3DSA:3.30.230.10 213 325 1.5E-32 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_17125 079a331dce0a80294e7c611c9650be02 631 Gene3D G3DSA:3.30.565.10 3 212 4.3E-62 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_17125 079a331dce0a80294e7c611c9650be02 631 Gene3D G3DSA:2.30.42.20 446 629 6.1E-64 T 12-10-2018 HW35_17125 079a331dce0a80294e7c611c9650be02 631 SMART SM01340 208 326 5.5E-53 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 HW35_17125 079a331dce0a80294e7c611c9650be02 631 Pfam PF08676 MutL C terminal dimerisation domain 446 587 1.3E-46 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 HW35_17125 079a331dce0a80294e7c611c9650be02 631 SUPERFAMILY SSF118116 441 629 6.15E-54 T 12-10-2018 IPR037198 MutL, C-terminal domain superfamily HW35_09235 e2596d5bb8e3dabb8613b6cab2ab0d02 123 SUPERFAMILY SSF52172 4 119 1.71E-38 T 12-10-2018 IPR011006 CheY-like superfamily HW35_09235 e2596d5bb8e3dabb8613b6cab2ab0d02 123 Pfam PF00072 Response regulator receiver domain 5 115 1.3E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_09235 e2596d5bb8e3dabb8613b6cab2ab0d02 123 Gene3D G3DSA:3.40.50.2300 1 123 6.3E-44 T 12-10-2018 HW35_09235 e2596d5bb8e3dabb8613b6cab2ab0d02 123 SMART SM00448 3 114 6.7E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 Gene3D G3DSA:1.10.460.10 170 601 1.8E-125 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 Gene3D G3DSA:3.40.50.140 2 162 1.5E-49 T 12-10-2018 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 SMART SM00493 2 135 5.7E-16 T 12-10-2018 IPR006171 TOPRIM domain HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 Pfam PF01131 DNA topoisomerase 163 591 3.8E-107 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 Gene3D G3DSA:2.70.20.10 223 481 1.8E-125 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 SMART SM00436 135 229 2.6E-21 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 SUPERFAMILY SSF56712 3 607 4.71E-155 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 396 412 9.6E-20 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 321 330 9.6E-20 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 199 217 9.6E-20 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 109 122 9.6E-20 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 519 533 9.6E-20 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 SMART SM00437 278 556 4.4E-55 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 Pfam PF01751 Toprim domain 4 143 1.2E-13 T 12-10-2018 IPR006171 TOPRIM domain HW35_02950 e68e0ee2a80cbe36e14e061cad0fe239 721 Gene3D G3DSA:1.10.290.10 287 410 1.8E-125 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 Pfam PF16657 Maltogenic Amylase, C-terminal domain 350 417 2.0E-6 T 12-10-2018 IPR032091 Maltogenic Amylase, C-terminal HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 SUPERFAMILY SSF51011 351 429 3.65E-10 T 12-10-2018 HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 Pfam PF00128 Alpha amylase, catalytic domain 65 139 4.5E-31 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 Pfam PF00128 Alpha amylase, catalytic domain 153 315 6.8E-12 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 SMART SM00642 37 341 1.4E-30 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 Gene3D G3DSA:3.20.20.80 27 141 2.3E-49 T 12-10-2018 HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 PIRSF PIRSF001024 1 157 2.2E-34 T 12-10-2018 IPR013777 Alpha-amylase-like GO:0004556|GO:0005509|GO:0005975 HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 PIRSF PIRSF001024 150 435 2.8E-22 T 12-10-2018 IPR013777 Alpha-amylase-like GO:0004556|GO:0005509|GO:0005975 HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 SUPERFAMILY SSF51445 26 350 6.43E-68 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 Gene3D G3DSA:3.20.20.80 142 345 1.9E-45 T 12-10-2018 HW35_15120 aeb51e76b27d198b5142a50ed06d6524 467 Gene3D G3DSA:2.60.40.1180 346 441 2.4E-35 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta HW35_07060 7ab08f6acb6879b953c561f2cee62cf5 146 Gene3D G3DSA:3.90.1010.10 1 146 4.3E-62 T 12-10-2018 HW35_07060 7ab08f6acb6879b953c561f2cee62cf5 146 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 140 1.6E-58 T 12-10-2018 HW35_07060 7ab08f6acb6879b953c561f2cee62cf5 146 SUPERFAMILY SSF82649 3 142 4.4E-54 T 12-10-2018 HW35_07060 7ab08f6acb6879b953c561f2cee62cf5 146 Pfam PF01592 NifU-like N terminal domain 10 128 2.1E-37 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 HW35_10875 97b9e7fb5560b865304d1086ec4c489f 145 SUPERFAMILY SSF52161 5 143 1.31E-61 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 HW35_10875 97b9e7fb5560b865304d1086ec4c489f 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 12-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 HW35_10875 97b9e7fb5560b865304d1086ec4c489f 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 28.731 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HW35_10875 97b9e7fb5560b865304d1086ec4c489f 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 1.4E-66 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10875 97b9e7fb5560b865304d1086ec4c489f 145 Pfam PF00572 Ribosomal protein L13 15 139 7.0E-60 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HW35_10875 97b9e7fb5560b865304d1086ec4c489f 145 PIRSF PIRSF002181 1 143 1.4E-52 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HW35_10875 97b9e7fb5560b865304d1086ec4c489f 145 Gene3D G3DSA:3.90.1180.10 1 143 2.5E-64 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 SUPERFAMILY SSF74731 2 116 7.59E-51 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.687 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 24 70 3.0E-11 T 12-10-2018 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 Gene3D G3DSA:1.10.1900.20 56 119 1.4E-28 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.1E-41 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.1E-41 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.1E-41 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 Pfam PF00453 Ribosomal protein L20 3 109 6.1E-50 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 Gene3D G3DSA:1.10.720.90 2 55 7.0E-27 T 12-10-2018 HW35_05560 9a141d0d1c8d7b23ab8d70e3e47de314 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.2E-51 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 106 598 9.9E-248 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 Gene3D G3DSA:1.20.58.760 403 605 2.3E-75 T 12-10-2018 HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 Gene3D G3DSA:1.10.8.60 328 402 1.4E-30 T 12-10-2018 HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 ProSitePatterns PS00674 AAA-protein family signature. 297 315 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 SUPERFAMILY SSF52540 150 398 5.12E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 SMART SM00382 190 329 3.6E-26 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 Gene3D G3DSA:3.40.50.300 145 327 2.7E-71 T 12-10-2018 HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 Pfam PF01434 Peptidase family M41 388 595 8.4E-88 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 612 38.99 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 194 326 3.5E-46 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 SUPERFAMILY SSF140990 408 603 4.19E-73 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 HW35_10360 ea56b90e8ff4e92266f1094d046eb7da 632 Pfam PF06480 FtsH Extracellular 9 90 3.8E-8 T 12-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 HW35_14090 3126732aea795591704f19c122169b72 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 2.1E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_14090 3126732aea795591704f19c122169b72 337 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_14090 3126732aea795591704f19c122169b72 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 322 3.4E-27 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_14090 3126732aea795591704f19c122169b72 337 Pfam PF00005 ABC transporter 27 185 2.0E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_14090 3126732aea795591704f19c122169b72 337 SUPERFAMILY SSF52540 6 256 4.33E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14090 3126732aea795591704f19c122169b72 337 SMART SM00382 35 243 1.4E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_14090 3126732aea795591704f19c122169b72 337 Gene3D G3DSA:3.40.50.300 4 334 5.6E-102 T 12-10-2018 HW35_01385 6d27f7ac2ccfef790e148131cfc50fb9 219 PIRSF PIRSF006293 2 218 3.4E-82 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HW35_01385 6d27f7ac2ccfef790e148131cfc50fb9 219 SUPERFAMILY SSF52402 3 212 2.87E-70 T 12-10-2018 HW35_01385 6d27f7ac2ccfef790e148131cfc50fb9 219 Pfam PF06508 Queuosine biosynthesis protein QueC 5 212 5.1E-88 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HW35_01385 6d27f7ac2ccfef790e148131cfc50fb9 219 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 205 1.0E-86 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HW35_01385 6d27f7ac2ccfef790e148131cfc50fb9 219 Gene3D G3DSA:3.40.50.620 2 218 4.3E-79 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_01385 6d27f7ac2ccfef790e148131cfc50fb9 219 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 218 52.482 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 Pfam PF03572 Peptidase family S41 231 393 1.7E-53 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 87 401 8.4E-116 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 Gene3D G3DSA:3.90.226.10 221 391 1.9E-95 T 12-10-2018 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 SUPERFAMILY SSF50156 123 216 4.78E-20 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 Pfam PF01471 Putative peptidoglycan binding domain 416 468 3.2E-14 T 12-10-2018 IPR002477 Peptidoglycan binding-like HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 Gene3D G3DSA:1.10.101.10 405 483 5.8E-17 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 Pfam PF13180 PDZ domain 134 212 6.4E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 Gene3D G3DSA:2.30.42.10 133 220 1.9E-95 T 12-10-2018 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 SMART SM00245 206 394 3.2E-70 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 SUPERFAMILY SSF47090 404 472 6.15E-16 T 12-10-2018 IPR036365 PGBD-like superfamily HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 SMART SM00228 133 204 1.4E-19 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 Gene3D G3DSA:3.30.750.44 80 369 1.9E-95 T 12-10-2018 HW35_02665 372ac70b588a1e9c25f56ee769e1ebf9 498 SUPERFAMILY SSF52096 77 398 1.82E-72 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_13250 2005539f514c465fb47445e2570602ad 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 HW35_13250 2005539f514c465fb47445e2570602ad 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 132 9.9E-36 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HW35_13250 2005539f514c465fb47445e2570602ad 346 SUPERFAMILY SSF51735 141 312 4.32E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_13250 2005539f514c465fb47445e2570602ad 346 Gene3D G3DSA:3.90.180.10 19 333 7.6E-98 T 12-10-2018 HW35_13250 2005539f514c465fb47445e2570602ad 346 Gene3D G3DSA:3.40.50.720 152 289 7.6E-98 T 12-10-2018 HW35_13250 2005539f514c465fb47445e2570602ad 346 SUPERFAMILY SSF50129 1 172 1.67E-50 T 12-10-2018 IPR011032 GroES-like superfamily HW35_13250 2005539f514c465fb47445e2570602ad 346 SMART SM00829 10 341 1.3E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HW35_13250 2005539f514c465fb47445e2570602ad 346 Pfam PF00107 Zinc-binding dehydrogenase 175 304 1.4E-22 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 HW35_06150 5b567849d878d68a539017459ead0659 267 Gene3D G3DSA:3.40.50.1820 1 261 2.7E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_06150 5b567849d878d68a539017459ead0659 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 38 53 6.8E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_06150 5b567849d878d68a539017459ead0659 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 6.8E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_06150 5b567849d878d68a539017459ead0659 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 6.8E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_06150 5b567849d878d68a539017459ead0659 267 Pfam PF12146 Serine aminopeptidase, S33 9 244 5.3E-59 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 HW35_06150 5b567849d878d68a539017459ead0659 267 SUPERFAMILY SSF53474 7 260 1.19E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 Gene3D G3DSA:2.30.30.30 118 196 3.1E-35 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 1.3E-57 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 5.1E-141 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 Gene3D G3DSA:2.40.50.140 1 114 5.2E-49 T 12-10-2018 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 SUPERFAMILY SSF50249 2 125 6.51E-52 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 PIRSF PIRSF002158 3 276 3.3E-100 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 SMART SM01383 42 118 1.2E-46 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 50.301 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 4.8E-34 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 Gene3D G3DSA:4.10.950.10 197 276 1.0E-36 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 SMART SM01382 124 253 1.4E-94 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 HW35_10730 7a3e77338e56ed316f28de74bf3e4c81 276 SUPERFAMILY SSF50104 126 273 1.2E-61 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily HW35_05550 c8e110e240cd967bca58c66905eb2b95 163 SUPERFAMILY SSF101386 2 163 2.4E-42 T 12-10-2018 HW35_05550 c8e110e240cd967bca58c66905eb2b95 163 Gene3D G3DSA:1.10.4010.10 1 163 4.8E-12 T 12-10-2018 HW35_05550 c8e110e240cd967bca58c66905eb2b95 163 PIRSF PIRSF030140 1 163 2.5E-55 T 12-10-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 HW35_05550 c8e110e240cd967bca58c66905eb2b95 163 Pfam PF08761 dUTPase 2 163 2.5E-47 T 12-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 9.4E-36 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 Gene3D G3DSA:1.20.120.1810 28 131 1.2E-25 T 12-10-2018 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 8 239 7.5E-135 T 12-10-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 Gene3D G3DSA:1.10.10.10 174 238 6.0E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_16385 53acae89d96ffad940e198a317d6d14c 239 SUPERFAMILY SSF88659 143 237 1.07E-21 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_16385 53acae89d96ffad940e198a317d6d14c 239 Pfam PF04545 Sigma-70, region 4 180 233 2.7E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 6.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 6.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 6.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 6.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 Pfam PF04542 Sigma-70 region 2 62 131 1.8E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 PIRSF PIRSF000770 2 239 4.3E-79 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_16385 53acae89d96ffad940e198a317d6d14c 239 SUPERFAMILY SSF88946 25 131 1.44E-35 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_02555 c8d736e3953f95193b733e051e258886 262 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 251 2.0E-89 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 HW35_02555 c8d736e3953f95193b733e051e258886 262 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 48 66 - T 12-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 HW35_02555 c8d736e3953f95193b733e051e258886 262 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 30 251 30.791 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 HW35_02555 c8d736e3953f95193b733e051e258886 262 SUPERFAMILY SSF51366 19 254 9.04E-82 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HW35_02555 c8d736e3953f95193b733e051e258886 262 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 255 34.818 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 HW35_02555 c8d736e3953f95193b733e051e258886 262 Gene3D G3DSA:3.20.20.70 1 257 2.8E-96 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_09655 83115a19fda0294cf6aec0bd1bb8a169 500 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 492 1.7E-241 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 HW35_09655 83115a19fda0294cf6aec0bd1bb8a169 500 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 492 54.579 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 HW35_09655 83115a19fda0294cf6aec0bd1bb8a169 500 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 490 1.6E-219 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 HW35_09655 83115a19fda0294cf6aec0bd1bb8a169 500 SUPERFAMILY SSF51905 7 315 3.89E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_09655 83115a19fda0294cf6aec0bd1bb8a169 500 Gene3D G3DSA:3.30.9.10 113 178 2.1E-7 T 12-10-2018 HW35_09655 83115a19fda0294cf6aec0bd1bb8a169 500 Gene3D G3DSA:3.50.50.60 10 257 2.1E-7 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_09460 5696153e21152736b0de1cd689bcb75f 462 PIRSF PIRSF006060 1 460 7.3E-64 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HW35_09460 5696153e21152736b0de1cd689bcb75f 462 Pfam PF00324 Amino acid permease 14 424 3.5E-97 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 HW35_09460 5696153e21152736b0de1cd689bcb75f 462 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 HW35_09460 5696153e21152736b0de1cd689bcb75f 462 Gene3D G3DSA:1.20.1740.10 5 457 2.8E-55 T 12-10-2018 HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 SUPERFAMILY SSF161093 281 448 1.83E-51 T 12-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 Pfam PF01769 Divalent cation transporter 320 441 4.5E-30 T 12-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 SUPERFAMILY SSF158791 8 133 1.02E-23 T 12-10-2018 HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 Pfam PF00571 CBS domain 136 194 2.7E-7 T 12-10-2018 IPR000644 CBS domain HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 Pfam PF00571 CBS domain 201 253 3.8E-8 T 12-10-2018 IPR000644 CBS domain HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 Gene3D G3DSA:1.25.60.10 4 131 4.7E-20 T 12-10-2018 IPR038076 MgtE, N-terminal domain superfamily HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 SUPERFAMILY SSF54631 135 266 1.77E-33 T 12-10-2018 HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 SMART SM00116 207 255 2.5E-6 T 12-10-2018 IPR000644 CBS domain HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 SMART SM00116 143 196 2.0 T 12-10-2018 IPR000644 CBS domain HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 TIGRFAM TIGR00400 mgtE: magnesium transporter 4 449 4.8E-166 T 12-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 Gene3D G3DSA:3.10.580.10 133 259 2.1E-44 T 12-10-2018 HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 Pfam PF03448 MgtE intracellular N domain 33 134 1.2E-20 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 Gene3D G3DSA:1.10.357.20 272 449 9.4E-58 T 12-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain HW35_11375 a9e92a61f7c63cd8d62a728fe757d170 452 SMART SM00924 33 136 8.2E-25 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain HW35_03110 35743caa5e4a652212aa29dfca32183a 232 SMART SM00100 15 133 2.9E-17 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain HW35_03110 35743caa5e4a652212aa29dfca32183a 232 SMART SM00419 171 221 1.4E-8 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_03110 35743caa5e4a652212aa29dfca32183a 232 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 179 195 3.6E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_03110 35743caa5e4a652212aa29dfca32183a 232 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 195 210 3.6E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_03110 35743caa5e4a652212aa29dfca32183a 232 Pfam PF13545 Crp-like helix-turn-helix domain 155 225 2.5E-14 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_03110 35743caa5e4a652212aa29dfca32183a 232 Pfam PF00027 Cyclic nucleotide-binding domain 34 118 1.3E-18 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain HW35_03110 35743caa5e4a652212aa29dfca32183a 232 Gene3D G3DSA:2.60.120.1460 19 228 4.2E-55 T 12-10-2018 HW35_03110 35743caa5e4a652212aa29dfca32183a 232 SUPERFAMILY SSF51206 9 145 3.4E-36 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like HW35_03110 35743caa5e4a652212aa29dfca32183a 232 SUPERFAMILY SSF46785 151 229 6.2E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_05545 6aa4fdf1cd8ea46b8246ab1d958dbc6e 361 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 3.7E-118 T 12-10-2018 IPR008007 Peptidase M42 HW35_05545 6aa4fdf1cd8ea46b8246ab1d958dbc6e 361 Gene3D G3DSA:3.40.630.10 12 345 2.7E-139 T 12-10-2018 HW35_05545 6aa4fdf1cd8ea46b8246ab1d958dbc6e 361 SUPERFAMILY SSF53187 6 357 3.77E-75 T 12-10-2018 HW35_05545 6aa4fdf1cd8ea46b8246ab1d958dbc6e 361 Gene3D G3DSA:2.40.30.40 77 164 2.7E-139 T 12-10-2018 IPR023367 Peptidase M42, domain 2 HW35_05545 6aa4fdf1cd8ea46b8246ab1d958dbc6e 361 SUPERFAMILY SSF101821 73 182 2.9E-35 T 12-10-2018 HW35_05545 6aa4fdf1cd8ea46b8246ab1d958dbc6e 361 PIRSF PIRSF001123 4 361 3.2E-151 T 12-10-2018 IPR008007 Peptidase M42 HW35_16635 98d5bf09880bf4d22dea0c36c1c39934 334 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 332 152.89 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 HW35_16635 98d5bf09880bf4d22dea0c36c1c39934 334 SUPERFAMILY SSF53659 1 324 1.07E-105 T 12-10-2018 HW35_16635 98d5bf09880bf4d22dea0c36c1c39934 334 Pfam PF02504 Fatty acid synthesis protein 1 318 1.6E-121 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 HW35_16635 98d5bf09880bf4d22dea0c36c1c39934 334 Gene3D G3DSA:3.40.718.10 1 333 2.0E-139 T 12-10-2018 HW35_16635 98d5bf09880bf4d22dea0c36c1c39934 334 PIRSF PIRSF002465 1 331 6.3E-131 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 HW35_16635 98d5bf09880bf4d22dea0c36c1c39934 334 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 327 2.0E-134 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 HW35_01080 1b2e2a4f8135cb6b4f65a59643d42d05 639 PIRSF PIRSF005091 1 618 6.3E-197 T 12-10-2018 IPR012160 Lipoteichoic acid synthase-like HW35_01080 1b2e2a4f8135cb6b4f65a59643d42d05 639 Gene3D G3DSA:3.40.720.10 234 542 5.3E-82 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 HW35_01080 1b2e2a4f8135cb6b4f65a59643d42d05 639 Pfam PF00884 Sulfatase 243 532 1.1E-39 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 HW35_01080 1b2e2a4f8135cb6b4f65a59643d42d05 639 SUPERFAMILY SSF53649 240 632 5.72E-81 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 Gene3D G3DSA:3.40.50.1260 8 391 5.6E-169 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 Pfam PF00162 Phosphoglycerate kinase 6 383 1.2E-168 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 PIRSF PIRSF000724 1 394 1.5E-162 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 Gene3D G3DSA:3.40.50.1260 169 383 5.6E-169 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 5.9E-101 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 5.9E-101 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 5.9E-101 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 5.9E-101 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 5.9E-101 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 5.9E-101 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 5.9E-101 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 5.9E-101 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 5.9E-101 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 43.549 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07410 a85c6d10465369453397bc1f4b436d84 394 SUPERFAMILY SSF53748 1 393 1.41E-165 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 171 1.3E-27 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 16 36 5.3E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 107 5.3E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 TIGRFAM TIGR00436 era: GTP-binding protein Era 14 285 2.2E-108 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 Pfam PF01926 50S ribosome-binding GTPase 16 130 1.9E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 SUPERFAMILY SSF54814 187 303 5.75E-43 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 Pfam PF07650 KH domain 213 291 1.8E-22 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 Hamap MF_00367 GTPase Era [era]. 11 302 39.146 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 SUPERFAMILY SSF52540 16 211 6.17E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 Gene3D G3DSA:3.30.300.20 191 304 2.3E-44 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta HW35_04465 4b92ec61c0b2493cbbbc202e4349cd59 307 Gene3D G3DSA:3.40.50.300 8 190 2.4E-50 T 12-10-2018 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 SUPERFAMILY SSF50621 278 431 1.9E-50 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 41.301 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 63 81 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 SUPERFAMILY SSF51419 30 299 2.13E-80 T 12-10-2018 IPR029066 PLP-binding barrel HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 Gene3D G3DSA:3.20.20.10 38 297 5.0E-156 T 12-10-2018 IPR029066 PLP-binding barrel HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 296 2.9E-73 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 Gene3D G3DSA:2.40.37.10 17 427 5.0E-156 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 4.6E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 4.6E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 4.6E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 4.6E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 10 430 3.0E-159 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 3.2E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 81 3.2E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 3.2E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 3.2E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 3.2E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HW35_03645 a9e884ad710fd5abfc7e642a4fc7b07e 434 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 34 388 2.5E-13 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 HW35_06555 dfefc766e585a3c02088272f98a4749c 228 Pfam PF02308 MgtC family 9 139 3.1E-34 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 HW35_06555 dfefc766e585a3c02088272f98a4749c 228 PRINTS PR01837 MgtC/SapB protein signature 12 31 3.6E-42 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 HW35_06555 dfefc766e585a3c02088272f98a4749c 228 PRINTS PR01837 MgtC/SapB protein signature 95 119 3.6E-42 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 HW35_06555 dfefc766e585a3c02088272f98a4749c 228 PRINTS PR01837 MgtC/SapB protein signature 67 89 3.6E-42 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 HW35_06555 dfefc766e585a3c02088272f98a4749c 228 PRINTS PR01837 MgtC/SapB protein signature 31 49 3.6E-42 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 HW35_12930 3589f9a8eb31d4469afd93fbfae63b1b 413 SUPERFAMILY SSF103473 15 402 1.96E-46 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_12930 3589f9a8eb31d4469afd93fbfae63b1b 413 Gene3D G3DSA:1.20.1250.20 12 400 3.1E-38 T 12-10-2018 HW35_12930 3589f9a8eb31d4469afd93fbfae63b1b 413 Pfam PF07690 Major Facilitator Superfamily 23 247 3.0E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_14930 f7693b6a5b088e3e536812bc8f47f805 175 Pfam PF17099 Tryptophan transporter TrpP 2 163 3.6E-52 T 12-10-2018 IPR031360 Tryptophan transporter TrpP HW35_14930 f7693b6a5b088e3e536812bc8f47f805 175 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 165 9.0E-50 T 12-10-2018 HW35_16545 21d2c99e0220a47e1a0598fa283252de 804 TIGRFAM TIGR00595 priA: primosomal protein N' 291 800 1.9E-218 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 HW35_16545 21d2c99e0220a47e1a0598fa283252de 804 SUPERFAMILY SSF52540 245 449 2.81E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16545 21d2c99e0220a47e1a0598fa283252de 804 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 803 24.952 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 HW35_16545 21d2c99e0220a47e1a0598fa283252de 804 Pfam PF04851 Type III restriction enzyme, res subunit 266 430 2.2E-18 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HW35_16545 21d2c99e0220a47e1a0598fa283252de 804 SMART SM00487 263 462 1.6E-29 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_16545 21d2c99e0220a47e1a0598fa283252de 804 Gene3D G3DSA:3.40.50.300 254 448 2.7E-75 T 12-10-2018 HW35_16545 21d2c99e0220a47e1a0598fa283252de 804 SUPERFAMILY SSF52540 531 702 7.8E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16545 21d2c99e0220a47e1a0598fa283252de 804 SMART SM00490 565 662 1.3E-10 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_16545 21d2c99e0220a47e1a0598fa283252de 804 Pfam PF00271 Helicase conserved C-terminal domain 578 661 5.4E-8 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_16545 21d2c99e0220a47e1a0598fa283252de 804 Gene3D G3DSA:1.10.8.630 2 114 1.2E-23 T 12-10-2018 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 PRINTS PR00046 Major sigma-70 factor signature 197 212 1.4E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 PRINTS PR00046 Major sigma-70 factor signature 212 223 1.4E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 PRINTS PR00046 Major sigma-70 factor signature 176 188 1.4E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 PRINTS PR00046 Major sigma-70 factor signature 78 91 1.4E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 Gene3D G3DSA:1.20.120.1810 22 123 1.2E-23 T 12-10-2018 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 Pfam PF04542 Sigma-70 region 2 54 123 1.1E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 PIRSF PIRSF000770 3 238 2.5E-89 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 197 223 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 SUPERFAMILY SSF88659 139 225 9.81E-19 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 5 228 5.7E-114 T 12-10-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 SUPERFAMILY SSF88946 10 120 3.53E-33 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 Gene3D G3DSA:1.10.10.10 154 234 3.8E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 Pfam PF04545 Sigma-70, region 4 173 223 7.6E-15 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 223 7.2E-31 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_04680 fc450bea4ae72134149d5ad66c8812f9 238 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Pfam PF00501 AMP-binding enzyme 450 839 2.0E-103 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Pfam PF00501 AMP-binding enzyme 1480 1890 3.1E-104 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Pfam PF13193 AMP-binding enzyme C-terminal domain 847 918 7.7E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Pfam PF13193 AMP-binding enzyme C-terminal domain 1898 1973 6.8E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Gene3D G3DSA:1.10.1200.10 933 1014 1.1E-24 T 12-10-2018 IPR036736 ACP-like superfamily HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SUPERFAMILY SSF56801 413 954 1.7E-150 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SUPERFAMILY SSF52777 1201 1465 9.34E-55 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Gene3D G3DSA:3.30.300.30 834 932 1.5E-33 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SUPERFAMILY SSF47336 1991 2062 6.15E-20 T 12-10-2018 IPR036736 ACP-like superfamily HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Gene3D G3DSA:3.30.559.10 1029 1387 3.6E-126 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Gene3D G3DSA:3.30.559.30 197 418 3.8E-50 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1625 1636 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SUPERFAMILY SSF47336 936 1008 3.93E-17 T 12-10-2018 IPR036736 ACP-like superfamily HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SUPERFAMILY SSF56801 1445 2010 2.22E-160 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SUPERFAMILY SSF52777 1030 1188 1.03E-36 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Gene3D G3DSA:3.30.559.30 1192 1445 3.6E-126 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SUPERFAMILY SSF52777 14 175 1.45E-24 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Pfam PF00975 Thioesterase domain 2083 2204 5.5E-32 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 471 863 1.2E-133 T 12-10-2018 IPR010071 Amino acid adenylation domain HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1501 1914 1.0E-134 T 12-10-2018 IPR010071 Amino acid adenylation domain HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Pfam PF00550 Phosphopantetheine attachment site 944 1005 3.3E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Pfam PF00550 Phosphopantetheine attachment site 1999 2060 6.0E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SUPERFAMILY SSF52777 181 438 3.89E-34 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Gene3D G3DSA:3.30.559.10 10 196 2.4E-34 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 ProSitePatterns PS00455 Putative AMP-binding domain signature. 587 598 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SMART SM00823 Phosphopantetheine attachment site 942 1011 0.0043 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SMART SM00823 Phosphopantetheine attachment site 1997 2066 1.0E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Gene3D G3DSA:3.30.300.30 1885 1988 1.4E-34 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Pfam PF00668 Condensation domain 1028 1456 4.2E-85 T 12-10-2018 IPR001242 Condensation domain HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Pfam PF00668 Condensation domain 4 430 2.5E-58 T 12-10-2018 IPR001242 Condensation domain HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 SUPERFAMILY SSF53474 2062 2324 1.38E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Gene3D G3DSA:3.40.50.1820 1989 2326 2.4E-105 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Gene3D G3DSA:3.40.50.12780 1467 1884 2.3E-143 T 12-10-2018 HW35_12765 603867b030cf6aef82a1b750e31a12e2 2334 Gene3D G3DSA:3.40.50.12780 437 833 5.5E-138 T 12-10-2018 HW35_09080 eddef1ca735b921c00c5f9f39920763b 134 SUPERFAMILY SSF46604 86 132 1.36E-7 T 12-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09080 eddef1ca735b921c00c5f9f39920763b 134 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 131 2.3E-41 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09080 eddef1ca735b921c00c5f9f39920763b 134 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 87 131 6.2E-17 T 12-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain HW35_09080 eddef1ca735b921c00c5f9f39920763b 134 SUPERFAMILY SSF51344 2 83 7.46E-25 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09080 eddef1ca735b921c00c5f9f39920763b 134 Gene3D G3DSA:1.20.5.440 89 134 1.4E-16 T 12-10-2018 HW35_09080 eddef1ca735b921c00c5f9f39920763b 134 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 82 1.2E-29 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09080 eddef1ca735b921c00c5f9f39920763b 134 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 88 1.0E-33 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09080 eddef1ca735b921c00c5f9f39920763b 134 Gene3D G3DSA:2.60.15.10 1 88 1.1E-34 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09080 eddef1ca735b921c00c5f9f39920763b 134 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 130 24.675 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_04665 2b5b2d8ed233fb97e615acd7bce1fbee 46 SUPERFAMILY SSF100985 2 45 2.09E-15 T 12-10-2018 IPR036916 Sporulation inhibitor A superfamily HW35_04665 2b5b2d8ed233fb97e615acd7bce1fbee 46 Pfam PF08970 Sporulation inhibitor A 3 43 2.1E-19 T 12-10-2018 IPR015064 Sporulation inhibitor A HW35_04665 2b5b2d8ed233fb97e615acd7bce1fbee 46 Gene3D G3DSA:1.10.287.1100 4 37 1.5E-19 T 12-10-2018 IPR036916 Sporulation inhibitor A superfamily HW35_05575 9dcc918044a52688375dc534148cb902 643 Gene3D G3DSA:3.10.20.30 2 65 6.9E-28 T 12-10-2018 IPR012675 Beta-grasp domain superfamily HW35_05575 9dcc918044a52688375dc534148cb902 643 Gene3D G3DSA:3.40.50.800 541 643 1.0E-34 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily HW35_05575 9dcc918044a52688375dc534148cb902 643 Gene3D G3DSA:3.30.930.10 227 540 2.8E-118 T 12-10-2018 HW35_05575 9dcc918044a52688375dc534148cb902 643 SUPERFAMILY SSF55681 245 534 3.19E-96 T 12-10-2018 HW35_05575 9dcc918044a52688375dc534148cb902 643 Gene3D G3DSA:3.30.54.20 133 189 7.5E-67 T 12-10-2018 HW35_05575 9dcc918044a52688375dc534148cb902 643 Pfam PF02824 TGS domain 5 64 1.9E-14 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 HW35_05575 9dcc918044a52688375dc534148cb902 643 Pfam PF03129 Anticodon binding domain 549 639 1.7E-24 T 12-10-2018 IPR004154 Anticodon-binding HW35_05575 9dcc918044a52688375dc534148cb902 643 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 221 1.9E-17 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 HW35_05575 9dcc918044a52688375dc534148cb902 643 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 326 537 3.0E-32 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_05575 9dcc918044a52688375dc534148cb902 643 Gene3D G3DSA:3.30.980.10 72 224 7.5E-67 T 12-10-2018 HW35_05575 9dcc918044a52688375dc534148cb902 643 SUPERFAMILY SSF52954 535 641 8.16E-32 T 12-10-2018 HW35_05575 9dcc918044a52688375dc534148cb902 643 SUPERFAMILY SSF55186 66 243 9.29E-68 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 HW35_05575 9dcc918044a52688375dc534148cb902 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 542 554 7.8E-48 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HW35_05575 9dcc918044a52688375dc534148cb902 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 472 500 7.8E-48 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HW35_05575 9dcc918044a52688375dc534148cb902 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 7.8E-48 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HW35_05575 9dcc918044a52688375dc534148cb902 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 7.8E-48 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HW35_05575 9dcc918044a52688375dc534148cb902 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 515 528 7.8E-48 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HW35_05575 9dcc918044a52688375dc534148cb902 643 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 643 35.509 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HW35_05575 9dcc918044a52688375dc534148cb902 643 SUPERFAMILY SSF81271 5 64 1.02E-17 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HW35_05575 9dcc918044a52688375dc534148cb902 643 SMART SM00863 172 221 4.2E-26 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 HW35_05575 9dcc918044a52688375dc534148cb902 643 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 640 2.1E-241 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HW35_10595 faa37582fe795097baa54a58d3ca11a4 228 SUPERFAMILY SSF53448 4 223 2.93E-61 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_10595 faa37582fe795097baa54a58d3ca11a4 228 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 223 7.7E-75 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HW35_10595 faa37582fe795097baa54a58d3ca11a4 228 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 222 44.284 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HW35_10595 faa37582fe795097baa54a58d3ca11a4 228 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 222 6.4E-76 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HW35_10595 faa37582fe795097baa54a58d3ca11a4 228 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 100 107 - T 12-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HW35_10595 faa37582fe795097baa54a58d3ca11a4 228 Gene3D G3DSA:3.90.550.10 1 228 1.2E-81 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 SUPERFAMILY SSF47831 23 143 4.05E-39 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 Gene3D G3DSA:1.10.274.10 23 146 1.9E-83 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 SUPERFAMILY SSF51621 249 549 2.04E-113 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 4.9E-32 T 12-10-2018 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 4.9E-32 T 12-10-2018 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 4.9E-32 T 12-10-2018 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 4.9E-32 T 12-10-2018 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 251 539 1.8E-129 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 Gene3D G3DSA:3.20.20.60 236 570 1.6E-128 T 12-10-2018 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 Pfam PF00391 PEP-utilising enzyme, mobile domain 153 225 4.3E-25 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 Pfam PF05524 PEP-utilising enzyme, N-terminal 5 126 2.2E-34 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 SUPERFAMILY SSF52009 125 246 1.7E-39 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 4 565 1.9E-256 T 12-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 PIRSF PIRSF000732 1 570 2.6E-229 T 12-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 HW35_15795 04abd0f71b365ffc786d5a365f65bc8f 570 Gene3D G3DSA:3.50.30.10 6 235 1.9E-83 T 12-10-2018 HW35_09220 0737feedc8b05f84803a3062a6894e83 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 405 3.9E-93 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HW35_09220 0737feedc8b05f84803a3062a6894e83 428 SUPERFAMILY SSF55205 1 414 1.64E-135 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HW35_09220 0737feedc8b05f84803a3062a6894e83 428 Gene3D G3DSA:3.65.10.10 21 228 2.3E-160 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 HW35_09220 0737feedc8b05f84803a3062a6894e83 428 Gene3D G3DSA:3.65.10.10 6 412 2.3E-160 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 HW35_09220 0737feedc8b05f84803a3062a6894e83 428 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 415 42.193 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_09220 0737feedc8b05f84803a3062a6894e83 428 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 414 1.3E-170 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_11720 70cceb30c82b32bf3996bda289f3226d 344 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 331 1.1E-141 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11720 70cceb30c82b32bf3996bda289f3226d 344 Pfam PF00586 AIR synthase related protein, N-terminal domain 71 161 6.1E-18 T 12-10-2018 IPR016188 PurM-like, N-terminal domain HW35_11720 70cceb30c82b32bf3996bda289f3226d 344 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 340 48.143 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11720 70cceb30c82b32bf3996bda289f3226d 344 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 334 8.0E-38 T 12-10-2018 IPR010918 PurM-like, C-terminal domain HW35_11720 70cceb30c82b32bf3996bda289f3226d 344 SUPERFAMILY SSF56042 169 335 2.84E-60 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HW35_11720 70cceb30c82b32bf3996bda289f3226d 344 Gene3D G3DSA:3.30.1330.10 1 167 1.7E-70 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HW35_11720 70cceb30c82b32bf3996bda289f3226d 344 SUPERFAMILY SSF55326 4 166 5.53E-52 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HW35_11720 70cceb30c82b32bf3996bda289f3226d 344 Gene3D G3DSA:3.90.650.10 168 342 1.5E-70 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HW35_00565 7bc2051f9c0225c82a24ba136bfe6e53 365 SUPERFAMILY SSF53383 6 363 4.82E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_00565 7bc2051f9c0225c82a24ba136bfe6e53 365 Gene3D G3DSA:3.90.1150.10 255 365 1.7E-40 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_00565 7bc2051f9c0225c82a24ba136bfe6e53 365 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 9 363 4.1E-157 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 HW35_00565 7bc2051f9c0225c82a24ba136bfe6e53 365 PIRSF PIRSF000525 3 365 7.6E-155 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 HW35_00565 7bc2051f9c0225c82a24ba136bfe6e53 365 Pfam PF00266 Aminotransferase class-V 9 346 3.8E-48 T 12-10-2018 IPR000192 Aminotransferase class V domain HW35_00565 7bc2051f9c0225c82a24ba136bfe6e53 365 Gene3D G3DSA:3.40.640.10 21 254 2.4E-90 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_00565 7bc2051f9c0225c82a24ba136bfe6e53 365 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 6 364 49.15 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 HW35_17535 cd4256a5afd9b524dd20dcdacaae234e 262 Gene3D G3DSA:3.60.160.10 1 249 1.5E-105 T 12-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily HW35_17535 cd4256a5afd9b524dd20dcdacaae234e 262 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 7 226 2.5E-36 T 12-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 HW35_17535 cd4256a5afd9b524dd20dcdacaae234e 262 Pfam PF01987 Mitochondrial biogenesis AIM24 8 225 1.3E-68 T 12-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 HW35_17535 cd4256a5afd9b524dd20dcdacaae234e 262 SUPERFAMILY SSF51219 6 244 1.2E-86 T 12-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily HW35_17335 2d1f3b530554980a5be3d28c7914d026 343 PIRSF PIRSF000089 5 334 8.0E-116 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 HW35_17335 2d1f3b530554980a5be3d28c7914d026 343 SUPERFAMILY SSF52467 209 328 2.33E-46 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily HW35_17335 2d1f3b530554980a5be3d28c7914d026 343 SUPERFAMILY SSF52402 7 203 6.98E-54 T 12-10-2018 HW35_17335 2d1f3b530554980a5be3d28c7914d026 343 Gene3D G3DSA:3.40.50.620 5 206 2.0E-72 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_17335 2d1f3b530554980a5be3d28c7914d026 343 SMART SM00893 9 198 1.9E-42 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HW35_17335 2d1f3b530554980a5be3d28c7914d026 343 Pfam PF01012 Electron transfer flavoprotein domain 9 186 9.4E-45 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HW35_17335 2d1f3b530554980a5be3d28c7914d026 343 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 210 292 8.7E-35 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 HW35_17335 2d1f3b530554980a5be3d28c7914d026 343 Gene3D G3DSA:3.40.50.1220 207 340 1.4E-55 T 12-10-2018 HW35_02490 0d7817ce892295e8b426292e35f46a41 220 Gene3D G3DSA:1.10.3720.10 1 219 2.4E-56 T 12-10-2018 IPR035906 MetI-like superfamily HW35_02490 0d7817ce892295e8b426292e35f46a41 220 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 216 8.5E-71 T 12-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 HW35_02490 0d7817ce892295e8b426292e35f46a41 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 214 1.6E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_02490 0d7817ce892295e8b426292e35f46a41 220 SUPERFAMILY SSF161098 2 211 1.96E-50 T 12-10-2018 IPR035906 MetI-like superfamily HW35_09530 9d6f8d2e9f672bd9d46a697dddd03999 259 Gene3D G3DSA:3.40.50.300 1 257 6.2E-64 T 12-10-2018 HW35_09530 9d6f8d2e9f672bd9d46a697dddd03999 259 SUPERFAMILY SSF52540 5 256 1.38E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09530 9d6f8d2e9f672bd9d46a697dddd03999 259 SMART SM00382 32 232 2.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_09530 9d6f8d2e9f672bd9d46a697dddd03999 259 Pfam PF00005 ABC transporter 24 183 1.3E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_09530 9d6f8d2e9f672bd9d46a697dddd03999 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 255 1.2E-13 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal HW35_09440 3962e4ce5cc4301fb382c9d5d3c277da 198 Gene3D G3DSA:3.90.550.10 1 195 8.7E-52 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_09440 3962e4ce5cc4301fb382c9d5d3c277da 198 SUPERFAMILY SSF53448 3 189 4.77E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_09440 3962e4ce5cc4301fb382c9d5d3c277da 198 Pfam PF12804 MobA-like NTP transferase domain 5 156 1.3E-27 T 12-10-2018 IPR025877 MobA-like NTP transferase HW35_09440 3962e4ce5cc4301fb382c9d5d3c277da 198 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 191 22.07 T 12-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 HW35_04705 c5b5588f192ca0bc924f398b854e21ae 377 Gene3D G3DSA:3.40.640.10 3 245 3.7E-94 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_04705 c5b5588f192ca0bc924f398b854e21ae 377 Gene3D G3DSA:3.90.1150.10 246 377 6.8E-55 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_04705 c5b5588f192ca0bc924f398b854e21ae 377 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_04705 c5b5588f192ca0bc924f398b854e21ae 377 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 377 3.9E-160 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_04705 c5b5588f192ca0bc924f398b854e21ae 377 PIRSF PIRSF001434 1 377 2.5E-151 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_04705 c5b5588f192ca0bc924f398b854e21ae 377 SUPERFAMILY SSF53383 5 377 1.2E-124 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 SUPERFAMILY SSF50249 2 136 1.29E-49 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 2.9E-69 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 PIRSF PIRSF002133 1 137 1.5E-49 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.613 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 Gene3D G3DSA:2.40.50.140 1 140 3.2E-63 T 12-10-2018 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 1.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 1.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 1.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 1.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 1.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 1.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10690 e0dfde97f22dda63e7d666e59abc43f2 140 Pfam PF00164 Ribosomal protein S12/S23 32 136 1.4E-38 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 SUPERFAMILY SSF53067 248 486 4.39E-68 T 12-10-2018 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 TIGRFAM TIGR01312 XylB: xylulokinase 5 483 2.9E-187 T 12-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 SUPERFAMILY SSF53067 2 248 1.64E-79 T 12-10-2018 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 131 143 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 354 374 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 Gene3D G3DSA:3.30.420.40 248 489 1.1E-74 T 12-10-2018 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 Gene3D G3DSA:3.30.420.40 1 246 1.9E-85 T 12-10-2018 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 PRINTS PR00475 Hexokinase family signature 5 21 6.7E-6 T 12-10-2018 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 PRINTS PR00475 Hexokinase family signature 424 440 6.7E-6 T 12-10-2018 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 255 441 1.1E-34 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 246 5.9E-71 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 HW35_11605 f0dd610cae77ae7b08de415ea4335dab 498 PIRSF PIRSF000538 1 493 1.8E-165 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HW35_09990 963f4888ec0c79241a4a91598e15c7ad 82 Pfam PF04025 Domain of unknown function (DUF370) 3 73 9.2E-13 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 80 3.4E-25 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 469 58.861 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 SMART SM00382 150 335 4.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 Gene3D G3DSA:1.10.1140.10 354 472 7.2E-58 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 Gene3D G3DSA:3.40.50.300 84 352 2.5E-117 T 12-10-2018 HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 469 2.1E-263 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 SUPERFAMILY SSF50615 1 82 1.16E-29 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 Gene3D G3DSA:2.40.10.170 1 82 1.7E-34 T 12-10-2018 HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 SUPERFAMILY SSF52540 84 355 8.04E-90 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 SUPERFAMILY SSF47917 354 469 4.19E-53 T 12-10-2018 HW35_09085 9fb196d55f035c81a08b72f501f1afe9 473 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 351 2.1E-68 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_11335 64ccd4ed5ae94e0dd1c95943468171a5 84 Gene3D G3DSA:1.10.8.910 25 84 1.7E-9 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily HW35_11335 64ccd4ed5ae94e0dd1c95943468171a5 84 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 80 9.3E-24 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 HW35_08120 9cd616cb74e7f3c8809a70f55ab65148 184 Gene3D G3DSA:3.40.50.450 1 184 5.7E-75 T 12-10-2018 HW35_08120 9cd616cb74e7f3c8809a70f55ab65148 184 SUPERFAMILY SSF102405 1 175 2.29E-61 T 12-10-2018 HW35_08120 9cd616cb74e7f3c8809a70f55ab65148 184 Pfam PF03641 Possible lysine decarboxylase 45 175 3.5E-42 T 12-10-2018 IPR031100 LOG family HW35_08120 9cd616cb74e7f3c8809a70f55ab65148 184 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 176 2.1E-63 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Pfam PF00682 HMGL-like 533 805 5.0E-25 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 SUPERFAMILY SSF89000 833 1010 9.81E-62 T 12-10-2018 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Gene3D G3DSA:3.10.600.10 510 1060 4.3E-294 T 12-10-2018 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 SUPERFAMILY SSF51569 525 836 5.86E-84 T 12-10-2018 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Gene3D G3DSA:3.10.600.10 463 509 7.8E-8 T 12-10-2018 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 289 296 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 7 1144 0.0 T 12-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 SMART SM00878 345 452 1.4E-50 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Pfam PF02785 Biotin carboxylase C-terminal domain 345 452 8.6E-32 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 SUPERFAMILY SSF52440 3 116 1.65E-45 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 119 325 4.6E-78 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Gene3D G3DSA:1.10.10.2790 943 978 4.3E-294 T 12-10-2018 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Gene3D G3DSA:3.30.470.130 1 460 4.3E-194 T 12-10-2018 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Pfam PF00364 Biotin-requiring enzyme 1078 1144 8.9E-18 T 12-10-2018 IPR000089 Biotin/lipoyl attachment HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Gene3D G3DSA:3.20.20.70 513 817 4.3E-294 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Pfam PF02436 Conserved carboxylase domain 828 1028 8.7E-81 T 12-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 SUPERFAMILY SSF56059 87 333 1.68E-67 T 12-10-2018 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 157 171 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 PIRSF PIRSF001594 1 1146 0.0 T 12-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 SUPERFAMILY SSF51230 1069 1144 1.44E-21 T 12-10-2018 IPR011053 Single hybrid motif HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Gene3D G3DSA:1.10.472.90 818 942 4.3E-294 T 12-10-2018 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Pfam PF00289 Biotin carboxylase, N-terminal domain 5 113 4.4E-43 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 Gene3D G3DSA:2.40.50.100 1068 1146 1.5E-23 T 12-10-2018 HW35_16070 bb170ab13570178a7f98a49677c28721 1147 SUPERFAMILY SSF51246 340 458 7.85E-38 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 HW35_14850 f434f8692451c4148f2868df81936454 289 Gene3D G3DSA:3.30.1240.10 87 196 1.6E-41 T 12-10-2018 HW35_14850 f434f8692451c4148f2868df81936454 289 SUPERFAMILY SSF56784 2 273 4.88E-55 T 12-10-2018 IPR036412 HAD-like superfamily HW35_14850 f434f8692451c4148f2868df81936454 289 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 241 7.6E-20 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 HW35_14850 f434f8692451c4148f2868df81936454 289 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 267 7.6E-50 T 12-10-2018 HW35_10205 47cc75efabac47fd645d3f0b8d0afbcd 255 SUPERFAMILY SSF51556 2 254 1.29E-98 T 12-10-2018 IPR032466 Metal-dependent hydrolase HW35_10205 47cc75efabac47fd645d3f0b8d0afbcd 255 Pfam PF01026 TatD related DNase 3 252 2.7E-91 T 12-10-2018 IPR001130 TatD family GO:0016788 HW35_10205 47cc75efabac47fd645d3f0b8d0afbcd 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 1.3E-101 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 HW35_10205 47cc75efabac47fd645d3f0b8d0afbcd 255 Gene3D G3DSA:3.20.20.140 1 255 1.2E-114 T 12-10-2018 HW35_10205 47cc75efabac47fd645d3f0b8d0afbcd 255 PIRSF PIRSF005902 1 255 2.5E-92 T 12-10-2018 IPR001130 TatD family GO:0016788 HW35_10205 47cc75efabac47fd645d3f0b8d0afbcd 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 HW35_10205 47cc75efabac47fd645d3f0b8d0afbcd 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 SUPERFAMILY SSF141868 443 688 1.7E-89 T 12-10-2018 IPR035919 EAL domain superfamily HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 Pfam PF00989 PAS fold 145 253 2.4E-11 T 12-10-2018 IPR013767 PAS fold GO:0006355 HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 Gene3D G3DSA:3.20.20.450 441 691 2.5E-98 T 12-10-2018 IPR035919 EAL domain superfamily HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 Pfam PF00990 Diguanylate cyclase, GGDEF domain 268 423 5.9E-42 T 12-10-2018 IPR000160 GGDEF domain HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 SUPERFAMILY SSF55073 273 428 1.73E-46 T 12-10-2018 IPR029787 Nucleotide cyclase HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 Gene3D G3DSA:3.30.450.20 14 134 2.3E-14 T 12-10-2018 HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 57 137 1.4E-8 T 12-10-2018 IPR000014 PAS domain HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 141 259 6.5E-20 T 12-10-2018 IPR000014 PAS domain HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 Gene3D G3DSA:3.30.70.270 263 440 6.7E-54 T 12-10-2018 HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 265 425 1.3E-38 T 12-10-2018 IPR000160 GGDEF domain HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 SMART SM00086 90 132 1.0 T 12-10-2018 IPR001610 PAC motif HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 SMART SM00086 216 257 10.0 T 12-10-2018 IPR001610 PAC motif HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 SMART SM00267 257 428 1.1E-54 T 12-10-2018 IPR000160 GGDEF domain HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 SMART SM00052 438 683 9.1E-115 T 12-10-2018 IPR001633 EAL domain HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 Gene3D G3DSA:3.30.450.20 135 254 3.3E-22 T 12-10-2018 HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 Pfam PF00563 EAL domain 445 678 1.3E-74 T 12-10-2018 IPR001633 EAL domain HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 SUPERFAMILY SSF55785 129 254 4.54E-22 T 12-10-2018 IPR035965 PAS domain superfamily HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 SMART SM00091 15 84 280.0 T 12-10-2018 IPR000014 PAS domain HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 SMART SM00091 144 210 1.0E-12 T 12-10-2018 IPR000014 PAS domain HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 SUPERFAMILY SSF55785 20 132 2.09E-11 T 12-10-2018 IPR035965 PAS domain superfamily HW35_15830 bf631b32a278eafdf648cc92c7a33461 699 Pfam PF08448 PAS fold 24 132 1.7E-9 T 12-10-2018 IPR013656 PAS fold-4 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 Pfam PF00141 Peroxidase 70 394 3.7E-51 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 Pfam PF00141 Peroxidase 401 700 1.6E-39 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 264 287 2.9E-60 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 69 94 2.9E-60 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 28 50 2.9E-60 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 478 504 2.9E-60 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 54 67 2.9E-60 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 18 726 0.0 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 SUPERFAMILY SSF48113 428 725 4.57E-113 T 12-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 Gene3D G3DSA:1.10.520.10 430 725 1.1E-151 T 12-10-2018 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 Gene3D G3DSA:1.10.520.10 23 429 4.5E-219 T 12-10-2018 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 Hamap MF_01961 Catalase-peroxidase [katG]. 7 726 42.454 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 Gene3D G3DSA:1.10.420.10 580 701 1.1E-151 T 12-10-2018 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 Gene3D G3DSA:1.10.420.20 193 396 4.5E-219 T 12-10-2018 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 SUPERFAMILY SSF48113 22 428 7.81E-163 T 12-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 PRINTS PR00458 Haem peroxidase superfamily signature 170 182 2.4E-23 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 PRINTS PR00458 Haem peroxidase superfamily signature 315 330 2.4E-23 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 PRINTS PR00458 Haem peroxidase superfamily signature 256 271 2.4E-23 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 PRINTS PR00458 Haem peroxidase superfamily signature 92 106 2.4E-23 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 PRINTS PR00458 Haem peroxidase superfamily signature 152 169 2.4E-23 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 ProSitePatterns PS00436 Peroxidases active site signature. 92 103 - T 12-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 HW35_17305 9422c4178f29ac9303d50f59f60b4744 738 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 256 266 - T 12-10-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 HW35_12955 ff45e196550de73494b2c48d4e5b4d88 136 Pfam PF04304 Protein of unknown function (DUF454) 9 124 1.3E-34 T 12-10-2018 IPR007401 Protein of unknown function DUF454 HW35_12955 ff45e196550de73494b2c48d4e5b4d88 136 PIRSF PIRSF016789 8 129 1.8E-31 T 12-10-2018 IPR007401 Protein of unknown function DUF454 HW35_00110 081ec4238c87c432c92c5599310b6c4b 191 PIRSF PIRSF006135 6 189 3.3E-43 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 HW35_00110 081ec4238c87c432c92c5599310b6c4b 191 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 8 184 1.9E-42 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 HW35_00110 081ec4238c87c432c92c5599310b6c4b 191 Gene3D G3DSA:3.40.50.300 7 187 1.8E-48 T 12-10-2018 HW35_00110 081ec4238c87c432c92c5599310b6c4b 191 SUPERFAMILY SSF52540 7 187 4.04E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15935 90b4321b584d91cff98c05bd0944775d 325 Gene3D G3DSA:3.40.50.920 193 325 6.8E-48 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HW35_15935 90b4321b584d91cff98c05bd0944775d 325 SMART SM00861 4 179 7.9E-68 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HW35_15935 90b4321b584d91cff98c05bd0944775d 325 Gene3D G3DSA:3.40.50.970 1 192 1.3E-83 T 12-10-2018 HW35_15935 90b4321b584d91cff98c05bd0944775d 325 Pfam PF02780 Transketolase, C-terminal domain 194 312 8.2E-40 T 12-10-2018 IPR033248 Transketolase, C-terminal domain HW35_15935 90b4321b584d91cff98c05bd0944775d 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 8.9E-41 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HW35_15935 90b4321b584d91cff98c05bd0944775d 325 SUPERFAMILY SSF52922 188 324 5.76E-42 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HW35_15935 90b4321b584d91cff98c05bd0944775d 325 SUPERFAMILY SSF52518 3 193 9.42E-68 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 Pfam PF13365 Trypsin-like peptidase domain 121 268 2.0E-30 T 12-10-2018 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 Gene3D G3DSA:2.30.42.10 309 409 1.8E-24 T 12-10-2018 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 Gene3D G3DSA:2.40.10.10 186 308 2.7E-37 T 12-10-2018 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 Gene3D G3DSA:2.40.10.10 52 184 5.2E-26 T 12-10-2018 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 SMART SM00228 306 395 3.5E-8 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 SUPERFAMILY SSF50494 84 302 7.86E-54 T 12-10-2018 IPR009003 Peptidase S1, PA clan HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 Pfam PF13180 PDZ domain 306 404 9.1E-17 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 SUPERFAMILY SSF50156 287 404 2.23E-18 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 PRINTS PR00834 HtrA/DegQ protease family signature 154 174 2.0E-33 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 PRINTS PR00834 HtrA/DegQ protease family signature 261 278 2.0E-33 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 PRINTS PR00834 HtrA/DegQ protease family signature 239 256 2.0E-33 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 PRINTS PR00834 HtrA/DegQ protease family signature 133 145 2.0E-33 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 PRINTS PR00834 HtrA/DegQ protease family signature 195 219 2.0E-33 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HW35_09780 29de2b12ffef4998d14e75930f55c7ab 410 PRINTS PR00834 HtrA/DegQ protease family signature 352 364 2.0E-33 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HW35_07745 d7c2b5343a2b7a195718dd81fc364717 309 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 4 296 39.796 T 12-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 HW35_07745 d7c2b5343a2b7a195718dd81fc364717 309 SUPERFAMILY SSF53697 8 250 1.4E-72 T 12-10-2018 HW35_07745 d7c2b5343a2b7a195718dd81fc364717 309 Gene3D G3DSA:3.40.50.10490 6 219 3.7E-76 T 12-10-2018 HW35_07745 d7c2b5343a2b7a195718dd81fc364717 309 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 8 297 4.5E-116 T 12-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 HW35_07745 d7c2b5343a2b7a195718dd81fc364717 309 Gene3D G3DSA:1.10.8.1080 220 298 1.8E-23 T 12-10-2018 HW35_07745 d7c2b5343a2b7a195718dd81fc364717 309 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 186 203 - T 12-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 HW35_07745 d7c2b5343a2b7a195718dd81fc364717 309 Pfam PF01380 SIS domain 126 209 4.5E-12 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HW35_03435 38e360eeed6993c2b825c64691781bff 225 SUPERFAMILY SSF52540 5 223 3.05E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03435 38e360eeed6993c2b825c64691781bff 225 Pfam PF02224 Cytidylate kinase 8 220 1.0E-78 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 HW35_03435 38e360eeed6993c2b825c64691781bff 225 Hamap MF_00238 Cytidylate kinase [cmk]. 6 224 34.143 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 HW35_03435 38e360eeed6993c2b825c64691781bff 225 Gene3D G3DSA:3.40.50.300 1 224 2.8E-88 T 12-10-2018 HW35_03435 38e360eeed6993c2b825c64691781bff 225 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 218 1.0E-86 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 HW35_09395 7450310525222f458f877ca34f3ff590 323 Pfam PF01515 Phosphate acetyl/butaryl transferase 6 319 7.8E-127 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HW35_09395 7450310525222f458f877ca34f3ff590 323 Gene3D G3DSA:3.40.50.10750 142 295 1.3E-132 T 12-10-2018 HW35_09395 7450310525222f458f877ca34f3ff590 323 SUPERFAMILY SSF53659 5 322 2.47E-92 T 12-10-2018 HW35_09395 7450310525222f458f877ca34f3ff590 323 Gene3D G3DSA:3.40.50.10950 18 319 1.3E-132 T 12-10-2018 HW35_09395 7450310525222f458f877ca34f3ff590 323 PIRSF PIRSF000428 1 323 1.5E-109 T 12-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HW35_09395 7450310525222f458f877ca34f3ff590 323 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 319 2.9E-124 T 12-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HW35_04615 788f9ca460dd7ef954c381f7bdea4ff1 274 PIRSF PIRSF000193 1 266 1.6E-67 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HW35_04615 788f9ca460dd7ef954c381f7bdea4ff1 274 Gene3D G3DSA:1.10.3730.10 162 263 1.0E-16 T 12-10-2018 HW35_04615 788f9ca460dd7ef954c381f7bdea4ff1 274 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 97 1.9E-17 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal HW35_04615 788f9ca460dd7ef954c381f7bdea4ff1 274 SUPERFAMILY SSF48179 158 262 1.21E-19 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_04615 788f9ca460dd7ef954c381f7bdea4ff1 274 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HW35_04615 788f9ca460dd7ef954c381f7bdea4ff1 274 SUPERFAMILY SSF51735 1 157 2.03E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_04615 788f9ca460dd7ef954c381f7bdea4ff1 274 Gene3D G3DSA:3.40.50.720 1 161 8.1E-29 T 12-10-2018 HW35_04615 788f9ca460dd7ef954c381f7bdea4ff1 274 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 161 262 2.4E-17 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HW35_06090 366e5d8dfc4cb7a535a32d0d3d20e23f 239 Pfam PF01479 S4 domain 1 45 3.9E-12 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_06090 366e5d8dfc4cb7a535a32d0d3d20e23f 239 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 227 3.3E-47 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 HW35_06090 366e5d8dfc4cb7a535a32d0d3d20e23f 239 Gene3D G3DSA:3.30.70.1560 129 212 3.4E-58 T 12-10-2018 HW35_06090 366e5d8dfc4cb7a535a32d0d3d20e23f 239 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 HW35_06090 366e5d8dfc4cb7a535a32d0d3d20e23f 239 Pfam PF00849 RNA pseudouridylate synthase 62 195 4.2E-20 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_06090 366e5d8dfc4cb7a535a32d0d3d20e23f 239 SUPERFAMILY SSF55120 46 235 3.2E-44 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_06090 366e5d8dfc4cb7a535a32d0d3d20e23f 239 Gene3D G3DSA:3.30.70.580 62 230 3.4E-58 T 12-10-2018 HW35_06090 366e5d8dfc4cb7a535a32d0d3d20e23f 239 Gene3D G3DSA:3.10.290.10 1 58 5.9E-17 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HW35_06090 366e5d8dfc4cb7a535a32d0d3d20e23f 239 SMART SM00363 1 59 6.7E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_06090 366e5d8dfc4cb7a535a32d0d3d20e23f 239 SUPERFAMILY SSF55174 1 59 3.34E-12 T 12-10-2018 HW35_08240 85df9dd7fd2ed9547092c8b8ee802428 324 Gene3D G3DSA:3.30.420.40 114 292 5.2E-86 T 12-10-2018 HW35_08240 85df9dd7fd2ed9547092c8b8ee802428 324 Gene3D G3DSA:3.30.420.40 3 304 5.2E-86 T 12-10-2018 HW35_08240 85df9dd7fd2ed9547092c8b8ee802428 324 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 298 2.0E-37 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 HW35_08240 85df9dd7fd2ed9547092c8b8ee802428 324 SUPERFAMILY SSF53067 2 112 2.07E-17 T 12-10-2018 HW35_08240 85df9dd7fd2ed9547092c8b8ee802428 324 SUPERFAMILY SSF53067 115 318 1.04E-47 T 12-10-2018 HW35_15565 282356b0ef5d8ed999cb659c99cb798e 463 PRINTS PR00095 Anthranilate synthase component I signature 312 325 3.5E-20 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_15565 282356b0ef5d8ed999cb659c99cb798e 463 PRINTS PR00095 Anthranilate synthase component I signature 298 311 3.5E-20 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_15565 282356b0ef5d8ed999cb659c99cb798e 463 PRINTS PR00095 Anthranilate synthase component I signature 392 406 3.5E-20 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_15565 282356b0ef5d8ed999cb659c99cb798e 463 PRINTS PR00095 Anthranilate synthase component I signature 407 421 3.5E-20 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_15565 282356b0ef5d8ed999cb659c99cb798e 463 Pfam PF04715 Anthranilate synthase component I, N terminal region 22 150 2.0E-31 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_15565 282356b0ef5d8ed999cb659c99cb798e 463 Pfam PF00425 chorismate binding enzyme 197 450 1.0E-98 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal HW35_15565 282356b0ef5d8ed999cb659c99cb798e 463 Gene3D G3DSA:3.60.120.10 2 463 3.6E-160 T 12-10-2018 IPR005801 ADC synthase GO:0009058 HW35_15565 282356b0ef5d8ed999cb659c99cb798e 463 SUPERFAMILY SSF56322 7 457 3.27E-144 T 12-10-2018 IPR005801 ADC synthase GO:0009058 HW35_06055 8cb6bfd746fdd24d366b048c453580f5 73 Pfam PF08220 DeoR-like helix-turn-helix domain 11 52 2.4E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HW35_06055 8cb6bfd746fdd24d366b048c453580f5 73 Gene3D G3DSA:1.10.10.10 10 72 5.1E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_06055 8cb6bfd746fdd24d366b048c453580f5 73 SUPERFAMILY SSF46785 7 62 1.03E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_06055 8cb6bfd746fdd24d366b048c453580f5 73 SMART SM00420 11 55 0.001 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HW35_02825 da33e253ad80ad2110ec47af2f08c1e6 126 Gene3D G3DSA:1.10.260.40 1 112 4.7E-29 T 12-10-2018 HW35_02825 da33e253ad80ad2110ec47af2f08c1e6 126 SUPERFAMILY SSF47406 75 107 3.92E-9 T 12-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 HW35_02825 da33e253ad80ad2110ec47af2f08c1e6 126 Pfam PF01381 Helix-turn-helix 6 61 8.2E-17 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_02825 da33e253ad80ad2110ec47af2f08c1e6 126 Pfam PF08671 Anti-repressor SinI 75 102 2.0E-9 T 12-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 HW35_02825 da33e253ad80ad2110ec47af2f08c1e6 126 SUPERFAMILY SSF47413 2 68 1.13E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_02825 da33e253ad80ad2110ec47af2f08c1e6 126 SMART SM00530 5 61 3.7E-18 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_01760 eaa1e9c6074927867151f97a4a9b4ac1 328 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 165 177 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 HW35_01760 eaa1e9c6074927867151f97a4a9b4ac1 328 PIRSF PIRSF036500 1 326 4.3E-193 T 12-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 HW35_01760 eaa1e9c6074927867151f97a4a9b4ac1 328 SMART SM01240 3 327 2.7E-122 T 12-10-2018 HW35_01760 eaa1e9c6074927867151f97a4a9b4ac1 328 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 4 324 6.6E-199 T 12-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 HW35_01760 eaa1e9c6074927867151f97a4a9b4ac1 328 SUPERFAMILY SSF51412 2 315 2.49E-95 T 12-10-2018 HW35_01760 eaa1e9c6074927867151f97a4a9b4ac1 328 Hamap MF_01511 GMP reductase [guaC]. 2 325 64.169 T 12-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 HW35_01760 eaa1e9c6074927867151f97a4a9b4ac1 328 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 6 310 6.5E-72 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 HW35_01760 eaa1e9c6074927867151f97a4a9b4ac1 328 Gene3D G3DSA:3.20.20.70 1 327 3.6E-112 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_04995 c272ffb014164bd6fe408cddff193ffb 367 Gene3D G3DSA:3.40.50.10800 28 347 4.2E-85 T 12-10-2018 HW35_04995 c272ffb014164bd6fe408cddff193ffb 367 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 20 367 2.1E-119 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HW35_04995 c272ffb014164bd6fe408cddff193ffb 367 Gene3D G3DSA:3.40.50.10800 111 364 4.2E-85 T 12-10-2018 HW35_04995 c272ffb014164bd6fe408cddff193ffb 367 Pfam PF02445 Quinolinate synthetase A protein 28 364 2.6E-109 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HW35_04995 c272ffb014164bd6fe408cddff193ffb 367 Hamap MF_00569 Quinolinate synthase A [nadA]. 21 366 56.158 T 12-10-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HW35_04995 c272ffb014164bd6fe408cddff193ffb 367 SUPERFAMILY SSF142754 33 365 3.14E-99 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HW35_04995 c272ffb014164bd6fe408cddff193ffb 367 Gene3D G3DSA:3.40.50.10800 229 316 4.2E-85 T 12-10-2018 HW35_03890 2a6cf3a4c5d7d7c2c2b3ee633caee687 331 Pfam PF00676 Dehydrogenase E1 component 21 320 1.5E-107 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 HW35_03890 2a6cf3a4c5d7d7c2c2b3ee633caee687 331 SUPERFAMILY SSF52518 7 330 8.6E-103 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_03890 2a6cf3a4c5d7d7c2c2b3ee633caee687 331 Gene3D G3DSA:3.40.50.970 1 331 1.8E-119 T 12-10-2018 HW35_13825 389896e9787059cbce3d0137902cf6c0 254 Pfam PF04892 VanZ like family 133 237 1.6E-23 T 12-10-2018 IPR006976 VanZ-like HW35_16490 448a97d76104c75e92a468d0bed67678 257 Gene3D G3DSA:2.10.240.10 214 257 1.1E-18 T 12-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily HW35_16490 448a97d76104c75e92a468d0bed67678 257 Pfam PF00970 Oxidoreductase FAD-binding domain 7 98 1.8E-6 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 HW35_16490 448a97d76104c75e92a468d0bed67678 257 Gene3D G3DSA:3.40.50.80 103 213 3.3E-24 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain HW35_16490 448a97d76104c75e92a468d0bed67678 257 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 214 255 2.4E-17 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain HW35_16490 448a97d76104c75e92a468d0bed67678 257 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 4 257 37.993 T 12-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit HW35_16490 448a97d76104c75e92a468d0bed67678 257 Gene3D G3DSA:2.40.30.10 2 98 2.4E-29 T 12-10-2018 HW35_16490 448a97d76104c75e92a468d0bed67678 257 SUPERFAMILY SSF52343 95 256 6.29E-27 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain HW35_16490 448a97d76104c75e92a468d0bed67678 257 SUPERFAMILY SSF63380 3 100 2.15E-22 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel HW35_16490 448a97d76104c75e92a468d0bed67678 257 PIRSF PIRSF006816 1 257 1.0E-73 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 HW35_14265 fdf02883d5a02a232ef61c0945596844 176 Hamap MF_01568 UPF0374 protein . 1 175 51.954 T 12-10-2018 IPR016882 Uncharacterised protein family UPF0374 HW35_14265 fdf02883d5a02a232ef61c0945596844 176 PIRSF PIRSF028345 1 176 2.3E-81 T 12-10-2018 IPR016882 Uncharacterised protein family UPF0374 HW35_14265 fdf02883d5a02a232ef61c0945596844 176 Pfam PF04167 Protein of unknown function (DUF402) 60 124 1.2E-17 T 12-10-2018 IPR007295 Domain of unknown function DUF402 HW35_14265 fdf02883d5a02a232ef61c0945596844 176 Gene3D G3DSA:2.40.380.10 22 169 8.6E-12 T 12-10-2018 IPR035930 FomD-like superfamily HW35_14265 fdf02883d5a02a232ef61c0945596844 176 SUPERFAMILY SSF159234 3 171 2.22E-32 T 12-10-2018 IPR035930 FomD-like superfamily HW35_16240 8702afb6bcd0f950699408c1e46a3c8f 207 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 4 78 6.2E-44 T 12-10-2018 IPR014243 Transcription factor, RsfA HW35_16240 8702afb6bcd0f950699408c1e46a3c8f 207 Gene3D G3DSA:1.10.10.60 8 92 1.8E-5 T 12-10-2018 HW35_16240 8702afb6bcd0f950699408c1e46a3c8f 207 Pfam PF13921 Myb-like DNA-binding domain 9 62 5.7E-6 T 12-10-2018 HW35_16240 8702afb6bcd0f950699408c1e46a3c8f 207 SUPERFAMILY SSF46689 6 62 7.18E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_07945 b30f68a11f02fbfbe37d1b295dfe965a 101 Gene3D G3DSA:1.10.3730.20 3 101 7.7E-6 T 12-10-2018 HW35_07945 b30f68a11f02fbfbe37d1b295dfe965a 101 SUPERFAMILY SSF103481 15 100 7.45E-15 T 12-10-2018 HW35_07945 b30f68a11f02fbfbe37d1b295dfe965a 101 Pfam PF00892 EamA-like transporter family 20 98 4.2E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 Gene3D G3DSA:1.10.8.60 619 710 2.2E-25 T 12-10-2018 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 Gene3D G3DSA:3.40.50.300 71 263 1.9E-67 T 12-10-2018 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 Pfam PF02151 UvrB/uvrC motif 336 370 1.1E-5 T 12-10-2018 IPR001943 UVR domain GO:0005515 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 Gene3D G3DSA:4.10.860.10 338 380 1.0E-6 T 12-10-2018 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 619 690 4.0E-23 T 12-10-2018 IPR019489 Clp ATPase, C-terminal HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 SUPERFAMILY SSF52540 84 335 7.1E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 Gene3D G3DSA:3.40.50.300 403 617 2.4E-83 T 12-10-2018 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 SMART SM01086 619 706 3.6E-30 T 12-10-2018 IPR019489 Clp ATPase, C-terminal HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 Pfam PF07724 AAA domain (Cdc48 subfamily) 448 611 1.5E-51 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 217 229 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 483 501 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 SMART SM00382 449 620 2.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 SMART SM00382 122 265 1.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 127 256 1.6E-11 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 560 574 2.2E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 527 545 2.2E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 498 516 2.2E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 453 471 2.2E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 HW35_15730 2c12b87a2e3736a0465d4b82ca67d1ac 711 SUPERFAMILY SSF52540 398 691 4.09E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03325 970d9d32f652dd352e103acaae46b678 372 SUPERFAMILY SSF53383 12 359 4.81E-80 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_03325 970d9d32f652dd352e103acaae46b678 372 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 357 2.4E-111 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 HW35_03325 970d9d32f652dd352e103acaae46b678 372 Gene3D G3DSA:3.40.640.10 43 267 2.6E-114 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_03325 970d9d32f652dd352e103acaae46b678 372 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 359 59.722 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 HW35_03325 970d9d32f652dd352e103acaae46b678 372 Gene3D G3DSA:3.90.1150.10 20 351 2.6E-114 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_03325 970d9d32f652dd352e103acaae46b678 372 Pfam PF00155 Aminotransferase class I and II 30 355 5.4E-59 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HW35_17570 8c6d9e65ef54e3fe628b9e62f89ff8e4 317 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 39 91 8.0E-19 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HW35_17570 8c6d9e65ef54e3fe628b9e62f89ff8e4 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 317 5.3E-33 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_17570 8c6d9e65ef54e3fe628b9e62f89ff8e4 317 Gene3D G3DSA:1.10.3720.10 104 317 1.4E-20 T 12-10-2018 IPR035906 MetI-like superfamily HW35_17570 8c6d9e65ef54e3fe628b9e62f89ff8e4 317 SUPERFAMILY SSF161098 112 316 6.54E-27 T 12-10-2018 IPR035906 MetI-like superfamily HW35_04330 8cd67bbcc1b18ae69d92ab1d4880505d 256 Pfam PF06691 Protein of unknown function (DUF1189) 4 246 5.5E-69 T 12-10-2018 IPR009574 Protein of unknown function DUF1189 HW35_06855 154446cd1012a9fe5ee8ba106ca282d0 401 Gene3D G3DSA:3.30.980.10 89 243 5.8E-46 T 12-10-2018 HW35_06855 154446cd1012a9fe5ee8ba106ca282d0 401 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 184 224 3.2E-7 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 HW35_06855 154446cd1012a9fe5ee8ba106ca282d0 401 Gene3D G3DSA:2.40.30.130 1 86 1.6E-25 T 12-10-2018 HW35_06855 154446cd1012a9fe5ee8ba106ca282d0 401 Pfam PF01411 tRNA synthetases class II (A) 16 92 8.0E-9 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 HW35_06855 154446cd1012a9fe5ee8ba106ca282d0 401 Pfam PF02272 DHHA1 domain 265 392 1.2E-7 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HW35_06855 154446cd1012a9fe5ee8ba106ca282d0 401 SUPERFAMILY SSF50447 2 74 4.24E-15 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_06855 154446cd1012a9fe5ee8ba106ca282d0 401 Gene3D G3DSA:3.10.310.40 296 396 3.2E-12 T 12-10-2018 HW35_06855 154446cd1012a9fe5ee8ba106ca282d0 401 SMART SM00863 184 226 8.2E-8 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 HW35_06855 154446cd1012a9fe5ee8ba106ca282d0 401 SUPERFAMILY SSF55186 92 233 3.53E-33 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 HW35_01285 a82bc7bb33e61b4e0c9e623f649c3f98 143 SUPERFAMILY SSF46785 4 140 9.35E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_01285 a82bc7bb33e61b4e0c9e623f649c3f98 143 SMART SM00347 24 124 1.4E-23 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_01285 a82bc7bb33e61b4e0c9e623f649c3f98 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 5.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_01285 a82bc7bb33e61b4e0c9e623f649c3f98 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 5.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_01285 a82bc7bb33e61b4e0c9e623f649c3f98 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 5.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_01285 a82bc7bb33e61b4e0c9e623f649c3f98 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 5.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_01285 a82bc7bb33e61b4e0c9e623f649c3f98 143 Gene3D G3DSA:1.10.10.10 1 141 4.1E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_01285 a82bc7bb33e61b4e0c9e623f649c3f98 143 Pfam PF12802 MarR family 29 88 2.1E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_07785 65d052cdc6cb2a63d69e575d877c45dc 126 SUPERFAMILY SSF46785 26 115 9.42E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_07785 65d052cdc6cb2a63d69e575d877c45dc 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 2.7E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_07785 65d052cdc6cb2a63d69e575d877c45dc 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 68 2.7E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_07785 65d052cdc6cb2a63d69e575d877c45dc 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 2.7E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_07785 65d052cdc6cb2a63d69e575d877c45dc 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 85 100 2.7E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_07785 65d052cdc6cb2a63d69e575d877c45dc 126 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 59 77 - T 12-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 HW35_07785 65d052cdc6cb2a63d69e575d877c45dc 126 Pfam PF01022 Bacterial regulatory protein, arsR family 42 88 6.1E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_07785 65d052cdc6cb2a63d69e575d877c45dc 126 Gene3D G3DSA:1.10.10.10 1 122 1.8E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_07785 65d052cdc6cb2a63d69e575d877c45dc 126 SMART SM00418 35 114 2.1E-31 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 4 563 2.5E-147 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 Gene3D G3DSA:3.30.1360.70 1 105 2.9E-28 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 Pfam PF05746 DALR anticodon binding domain 450 563 6.4E-33 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 SMART SM00836 450 563 4.4E-36 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 2.9E-18 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 2.9E-18 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 2.9E-18 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 2.9E-18 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 SUPERFAMILY SSF55190 3 105 2.75E-23 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 SMART SM01016 5 84 2.6E-23 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 Gene3D G3DSA:1.10.730.10 444 563 1.6E-35 T 12-10-2018 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 Pfam PF00750 tRNA synthetases class I (R) 94 435 3.0E-95 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 SUPERFAMILY SSF47323 444 563 6.11E-33 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 6 84 7.7E-16 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 SUPERFAMILY SSF52374 110 444 6.26E-97 T 12-10-2018 HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 Gene3D G3DSA:3.40.50.620 109 443 4.3E-121 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_11340 0670ad142479554d31daf5e2f54ff8f7 563 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 563 25.228 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_00700 f29ae6639f19425bf74896bb686d3ff6 255 SUPERFAMILY SSF161098 60 238 9.81E-32 T 12-10-2018 IPR035906 MetI-like superfamily HW35_00700 f29ae6639f19425bf74896bb686d3ff6 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 250 3.1E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_00700 f29ae6639f19425bf74896bb686d3ff6 255 Gene3D G3DSA:1.10.3720.10 52 252 1.0E-26 T 12-10-2018 IPR035906 MetI-like superfamily HW35_14115 c12c0e63ae0a7f5a4ab1a0f10e9af462 178 Gene3D G3DSA:3.40.50.300 5 177 1.8E-49 T 12-10-2018 HW35_14115 c12c0e63ae0a7f5a4ab1a0f10e9af462 178 ProSitePatterns PS01128 Shikimate kinase signature. 63 88 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 HW35_14115 c12c0e63ae0a7f5a4ab1a0f10e9af462 178 Pfam PF01202 Shikimate kinase 16 171 7.8E-45 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 HW35_14115 c12c0e63ae0a7f5a4ab1a0f10e9af462 178 Hamap MF_00109 Shikimate kinase [aroK]. 7 172 25.64 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 HW35_14115 c12c0e63ae0a7f5a4ab1a0f10e9af462 178 SUPERFAMILY SSF52540 9 171 1.59E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14115 c12c0e63ae0a7f5a4ab1a0f10e9af462 178 PRINTS PR01100 Shikimate kinase family signature 80 89 4.7E-21 T 12-10-2018 HW35_14115 c12c0e63ae0a7f5a4ab1a0f10e9af462 178 PRINTS PR01100 Shikimate kinase family signature 101 118 4.7E-21 T 12-10-2018 HW35_14115 c12c0e63ae0a7f5a4ab1a0f10e9af462 178 PRINTS PR01100 Shikimate kinase family signature 62 70 4.7E-21 T 12-10-2018 HW35_14115 c12c0e63ae0a7f5a4ab1a0f10e9af462 178 PRINTS PR01100 Shikimate kinase family signature 34 47 4.7E-21 T 12-10-2018 HW35_14115 c12c0e63ae0a7f5a4ab1a0f10e9af462 178 PRINTS PR01100 Shikimate kinase family signature 10 25 4.7E-21 T 12-10-2018 HW35_15635 4d172bc592a7613c622207169b680ab4 67 Gene3D G3DSA:1.10.8.910 6 67 4.2E-29 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily HW35_15635 4d172bc592a7613c622207169b680ab4 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 6 60 2.6E-20 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 HW35_15635 4d172bc592a7613c622207169b680ab4 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 21 30 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HW35_15635 4d172bc592a7613c622207169b680ab4 67 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 39 53 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HW35_16270 93557ded00a0f437488303d58a7b551c 130 Pfam PF11877 Protein of unknown function (DUF3397) 10 120 1.2E-29 T 12-10-2018 IPR024515 Protein of unknown function DUF3397 HW35_16270 93557ded00a0f437488303d58a7b551c 130 PIRSF PIRSF030092 1 128 8.4E-33 T 12-10-2018 IPR016945 Uncharacterised conserved protein UCP030092 HW35_09150 8ae7a63c12a7a2fcef06473f0396982d 188 Hamap MF_00800 UPF0340 protein . 1 188 92.509 T 12-10-2018 IPR006340 Protein of unknown function DUF436 HW35_09150 8ae7a63c12a7a2fcef06473f0396982d 188 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 13 178 7.0E-67 T 12-10-2018 IPR006340 Protein of unknown function DUF436 HW35_09150 8ae7a63c12a7a2fcef06473f0396982d 188 Pfam PF04260 Protein of unknown function (DUF436) 10 178 3.7E-77 T 12-10-2018 IPR006340 Protein of unknown function DUF436 HW35_09150 8ae7a63c12a7a2fcef06473f0396982d 188 Gene3D G3DSA:3.40.50.10360 2 188 3.1E-80 T 12-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like HW35_09150 8ae7a63c12a7a2fcef06473f0396982d 188 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 7 178 1.2E-75 T 12-10-2018 IPR006340 Protein of unknown function DUF436 HW35_09150 8ae7a63c12a7a2fcef06473f0396982d 188 PIRSF PIRSF007510 1 181 1.6E-79 T 12-10-2018 IPR006340 Protein of unknown function DUF436 HW35_09150 8ae7a63c12a7a2fcef06473f0396982d 188 SUPERFAMILY SSF110710 3 185 1.28E-77 T 12-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like HW35_15400 193f5fd359ad963f19d045f98b0eb7b8 246 PRINTS PR00114 Serine/threonine phosphatase family signature 2 29 4.4E-7 T 12-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_15400 193f5fd359ad963f19d045f98b0eb7b8 246 PRINTS PR00114 Serine/threonine phosphatase family signature 40 67 4.4E-7 T 12-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_15400 193f5fd359ad963f19d045f98b0eb7b8 246 Gene3D G3DSA:3.60.21.10 1 246 4.6E-64 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like HW35_15400 193f5fd359ad963f19d045f98b0eb7b8 246 Hamap MF_01443 Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical] [prpE]. 1 246 58.382 T 12-10-2018 IPR023937 Bis(5'-nucleosyl)-tetraphosphatase PrpE GO:0004081|GO:0016151 KEGG: 00230+3.6.1.17|KEGG: 00240+3.6.1.17 HW35_15400 193f5fd359ad963f19d045f98b0eb7b8 246 SUPERFAMILY SSF56300 1 223 3.24E-42 T 12-10-2018 HW35_15400 193f5fd359ad963f19d045f98b0eb7b8 246 Pfam PF00149 Calcineurin-like phosphoesterase 1 197 6.4E-15 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 HW35_02860 4dac0c59332d6483fd6f6e2a4cc7c9e4 192 Gene3D G3DSA:2.60.60.30 19 187 4.8E-72 T 12-10-2018 HW35_02860 4dac0c59332d6483fd6f6e2a4cc7c9e4 192 Pfam PF02342 TerD domain 2 188 1.2E-83 T 12-10-2018 IPR003325 TerD domain HW35_08550 dc5588d9684ca611a833ce9ebf799358 89 SUPERFAMILY SSF52794 1 87 1.28E-18 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_08550 dc5588d9684ca611a833ce9ebf799358 89 Gene3D G3DSA:3.40.50.2300 1 88 1.1E-21 T 12-10-2018 HW35_08550 dc5588d9684ca611a833ce9ebf799358 89 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 86 5.1E-15 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HW35_03025 766e963121a177d13f4f31823ffc0196 159 Gene3D G3DSA:2.60.40.420 25 156 5.3E-30 T 12-10-2018 IPR008972 Cupredoxin HW35_03025 766e963121a177d13f4f31823ffc0196 159 SUPERFAMILY SSF49503 32 157 1.51E-25 T 12-10-2018 IPR008972 Cupredoxin HW35_03025 766e963121a177d13f4f31823ffc0196 159 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 84 156 2.4E-10 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_03025 766e963121a177d13f4f31823ffc0196 159 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 102 150 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_10855 d8fe353e7923733c8a350e1907ad9015 280 Pfam PF00005 ABC transporter 24 170 1.3E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_10855 d8fe353e7923733c8a350e1907ad9015 280 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_10855 d8fe353e7923733c8a350e1907ad9015 280 SUPERFAMILY SSF52540 5 230 8.84E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10855 d8fe353e7923733c8a350e1907ad9015 280 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 7 274 3.0E-122 T 12-10-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 HW35_10855 d8fe353e7923733c8a350e1907ad9015 280 SMART SM00382 33 218 2.4E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_10855 d8fe353e7923733c8a350e1907ad9015 280 Gene3D G3DSA:3.40.50.300 3 279 1.0E-79 T 12-10-2018 HW35_03595 1aa54b77dbcb79580dacdd3a72c5a547 381 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 24 253 9.8E-76 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HW35_03595 1aa54b77dbcb79580dacdd3a72c5a547 381 Gene3D G3DSA:2.30.140.30 274 361 9.9E-20 T 12-10-2018 HW35_03595 1aa54b77dbcb79580dacdd3a72c5a547 381 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 271 356 1.2E-4 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_03595 1aa54b77dbcb79580dacdd3a72c5a547 381 SUPERFAMILY SSF56601 1 270 1.72E-72 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_03595 1aa54b77dbcb79580dacdd3a72c5a547 381 SUPERFAMILY SSF69189 262 356 3.92E-5 T 12-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_03595 1aa54b77dbcb79580dacdd3a72c5a547 381 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 134 147 1.5E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_03595 1aa54b77dbcb79580dacdd3a72c5a547 381 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 59 70 1.5E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_03595 1aa54b77dbcb79580dacdd3a72c5a547 381 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 107 124 1.5E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_03595 1aa54b77dbcb79580dacdd3a72c5a547 381 Gene3D G3DSA:3.40.710.10 18 273 1.1E-91 T 12-10-2018 HW35_12050 bfa7dfbc442f43887ced19a6e1b6ec0a 410 SUPERFAMILY SSF53187 6 407 8.38E-92 T 12-10-2018 HW35_12050 bfa7dfbc442f43887ced19a6e1b6ec0a 410 Pfam PF01546 Peptidase family M20/M25/M40 80 403 1.2E-32 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 HW35_12050 bfa7dfbc442f43887ced19a6e1b6ec0a 410 SUPERFAMILY SSF55031 213 307 1.45E-21 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain HW35_12050 bfa7dfbc442f43887ced19a6e1b6ec0a 410 PIRSF PIRSF001235 6 410 1.3E-138 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 HW35_12050 bfa7dfbc442f43887ced19a6e1b6ec0a 410 Gene3D G3DSA:3.30.70.360 213 326 4.1E-142 T 12-10-2018 HW35_12050 bfa7dfbc442f43887ced19a6e1b6ec0a 410 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 11 406 2.7E-127 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 HW35_12050 bfa7dfbc442f43887ced19a6e1b6ec0a 410 Gene3D G3DSA:3.40.630.10 18 402 4.1E-142 T 12-10-2018 HW35_07590 5db3fc15f866f81c2b473a3979b77ff2 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 12-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site HW35_07590 5db3fc15f866f81c2b473a3979b77ff2 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 1.8E-29 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like HW35_07590 5db3fc15f866f81c2b473a3979b77ff2 85 SUPERFAMILY SSF55594 4 84 1.7E-27 T 12-10-2018 IPR035895 HPr-like superfamily HW35_07590 5db3fc15f866f81c2b473a3979b77ff2 85 Pfam PF00381 PTS HPr component phosphorylation site 4 82 5.6E-29 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like HW35_07590 5db3fc15f866f81c2b473a3979b77ff2 85 Gene3D G3DSA:3.30.1340.10 1 85 7.4E-34 T 12-10-2018 IPR035895 HPr-like superfamily HW35_07590 5db3fc15f866f81c2b473a3979b77ff2 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.5E-20 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like HW35_07590 5db3fc15f866f81c2b473a3979b77ff2 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.5E-20 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like HW35_07590 5db3fc15f866f81c2b473a3979b77ff2 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.5E-20 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like HW35_16245 e8406e66b71fe876ce7e57f56f4edbbe 155 Gene3D G3DSA:3.40.630.30 2 154 2.3E-59 T 12-10-2018 HW35_16245 e8406e66b71fe876ce7e57f56f4edbbe 155 PIRSF PIRSF037732 1 155 3.2E-83 T 12-10-2018 IPR017274 Putative N-acetyltransferase YlbP HW35_16245 e8406e66b71fe876ce7e57f56f4edbbe 155 Pfam PF00583 Acetyltransferase (GNAT) family 41 129 1.3E-9 T 12-10-2018 IPR000182 GNAT domain HW35_16245 e8406e66b71fe876ce7e57f56f4edbbe 155 Hamap MF_00824 Uncharacterized N-acetyltransferase . 2 149 42.057 T 12-10-2018 IPR017274 Putative N-acetyltransferase YlbP HW35_16245 e8406e66b71fe876ce7e57f56f4edbbe 155 SUPERFAMILY SSF55729 25 141 2.33E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_12485 4388574c6416beab323223f8360a7626 336 Pfam PF07854 Protein of unknown function (DUF1646) 3 335 1.3E-122 T 12-10-2018 IPR012443 Protein of unknown function DUF1646 HW35_12485 4388574c6416beab323223f8360a7626 336 PIRSF PIRSF019205 1 336 1.7E-131 T 12-10-2018 IPR012443 Protein of unknown function DUF1646 HW35_05885 d3e5ba05f32aa76718550668f3f6ad70 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 91 3.4E-30 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 HW35_05885 d3e5ba05f32aa76718550668f3f6ad70 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 9.7E-87 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 HW35_05885 d3e5ba05f32aa76718550668f3f6ad70 200 Gene3D G3DSA:1.10.1050.10 6 200 7.8E-78 T 12-10-2018 HW35_05885 d3e5ba05f32aa76718550668f3f6ad70 200 SMART SM00363 92 156 7.6E-20 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_05885 d3e5ba05f32aa76718550668f3f6ad70 200 SMART SM01390 3 91 3.9E-49 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 HW35_05885 d3e5ba05f32aa76718550668f3f6ad70 200 Pfam PF01479 S4 domain 93 139 3.1E-20 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_05885 d3e5ba05f32aa76718550668f3f6ad70 200 Gene3D G3DSA:3.10.290.10 91 185 7.8E-78 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HW35_05885 d3e5ba05f32aa76718550668f3f6ad70 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 37.179 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 HW35_05885 d3e5ba05f32aa76718550668f3f6ad70 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_05885 d3e5ba05f32aa76718550668f3f6ad70 200 SUPERFAMILY SSF55174 2 200 2.62E-71 T 12-10-2018 HW35_03260 4267051cc757ade06413643a448efd6f 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 217 7.7E-66 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT HW35_03260 4267051cc757ade06413643a448efd6f 290 PIRSF PIRSF006483 2 284 8.1E-98 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT HW35_03260 4267051cc757ade06413643a448efd6f 290 Gene3D G3DSA:3.30.70.120 194 269 1.2E-27 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HW35_03260 4267051cc757ade06413643a448efd6f 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 222 276 8.2E-23 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 HW35_11130 7d93e2e31b4b7bbc1229efa8cbab846c 289 Pfam PF16916 Dimerisation domain of Zinc Transporter 221 288 3.5E-15 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain HW35_11130 7d93e2e31b4b7bbc1229efa8cbab846c 289 SUPERFAMILY SSF161111 9 210 1.7E-51 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily HW35_11130 7d93e2e31b4b7bbc1229efa8cbab846c 289 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 288 9.6E-65 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HW35_11130 7d93e2e31b4b7bbc1229efa8cbab846c 289 SUPERFAMILY SSF160240 216 288 1.96E-16 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 HW35_11130 7d93e2e31b4b7bbc1229efa8cbab846c 289 Gene3D G3DSA:3.30.70.1350 209 289 4.9E-15 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 HW35_11130 7d93e2e31b4b7bbc1229efa8cbab846c 289 Gene3D G3DSA:1.20.1510.10 12 208 1.8E-52 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily HW35_11130 7d93e2e31b4b7bbc1229efa8cbab846c 289 Pfam PF01545 Cation efflux family 17 208 3.8E-45 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 SUPERFAMILY SSF54631 204 341 2.53E-28 T 12-10-2018 HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 SMART SM01091 354 431 4.4E-22 T 12-10-2018 IPR005170 Transporter-associated domain HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 SUPERFAMILY SSF56176 351 437 2.73E-18 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 Gene3D G3DSA:3.30.465.10 351 440 6.2E-18 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 Pfam PF00571 CBS domain 217 269 1.3E-4 T 12-10-2018 IPR000644 CBS domain HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 Pfam PF00571 CBS domain 289 338 5.4E-5 T 12-10-2018 IPR000644 CBS domain HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 Gene3D G3DSA:3.10.580.10 197 350 5.3E-48 T 12-10-2018 HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 SMART SM00116 225 278 1.6 T 12-10-2018 IPR000644 CBS domain HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 SMART SM00116 290 338 12.0 T 12-10-2018 IPR000644 CBS domain HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 Pfam PF03471 Transporter associated domain 355 429 1.3E-16 T 12-10-2018 IPR005170 Transporter-associated domain HW35_14770 0e454ac521aaeaf7d06b0ac2757ae719 450 Pfam PF01595 Domain of unknown function DUF21 8 201 5.3E-48 T 12-10-2018 IPR002550 CNNM, transmembrane domain HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 Pfam PF06445 GyrI-like small molecule binding domain 128 288 2.7E-27 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 Pfam PF12833 Helix-turn-helix domain 28 104 5.6E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 SUPERFAMILY SSF46689 57 111 3.05E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 SUPERFAMILY SSF46689 5 55 4.93E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 Gene3D G3DSA:1.10.10.60 58 116 9.6E-14 T 12-10-2018 HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 SMART SM00871 128 288 5.0E-32 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 8.8E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 8.8E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 SMART SM00342 21 104 5.1E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 Gene3D G3DSA:1.10.10.60 2 57 9.7E-15 T 12-10-2018 HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 Gene3D G3DSA:3.20.80.10 128 291 3.4E-38 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily HW35_13850 f7b074449aefa6a5b81527c35a7c2ad0 291 SUPERFAMILY SSF55136 128 290 2.07E-30 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily HW35_10740 eab65f295bd4951a3976696ac5a24d23 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 2.6E-38 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 HW35_10740 eab65f295bd4951a3976696ac5a24d23 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10740 eab65f295bd4951a3976696ac5a24d23 113 SUPERFAMILY SSF54843 1 112 6.28E-45 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 HW35_10740 eab65f295bd4951a3976696ac5a24d23 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 106 3.6E-53 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10740 eab65f295bd4951a3976696ac5a24d23 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.926 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10740 eab65f295bd4951a3976696ac5a24d23 113 Gene3D G3DSA:3.90.470.10 1 113 9.0E-52 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 HW35_03505 0ec259185a29f30f3572c3eb01e4e611 241 SMART SM00257 193 239 3.6E-9 T 12-10-2018 IPR018392 LysM domain HW35_03505 0ec259185a29f30f3572c3eb01e4e611 241 Gene3D G3DSA:3.10.350.10 179 241 8.9E-13 T 12-10-2018 IPR036779 LysM domain superfamily HW35_03505 0ec259185a29f30f3572c3eb01e4e611 241 Pfam PF01476 LysM domain 194 239 8.2E-9 T 12-10-2018 IPR018392 LysM domain HW35_03505 0ec259185a29f30f3572c3eb01e4e611 241 SUPERFAMILY SSF54106 192 239 1.83E-7 T 12-10-2018 HW35_10625 583ed40fe636d1c51336a1564ada79cf 247 Gene3D G3DSA:3.40.1280.10 75 243 5.0E-56 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HW35_10625 583ed40fe636d1c51336a1564ada79cf 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 79 8.2E-21 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HW35_10625 583ed40fe636d1c51336a1564ada79cf 247 Gene3D G3DSA:3.30.1330.30 1 74 3.5E-10 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like HW35_10625 583ed40fe636d1c51336a1564ada79cf 247 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 242 3.8E-84 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 HW35_10625 583ed40fe636d1c51336a1564ada79cf 247 SMART SM00967 5 79 1.1E-21 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HW35_10625 583ed40fe636d1c51336a1564ada79cf 247 Pfam PF00588 SpoU rRNA Methylase family 96 236 5.5E-38 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HW35_10625 583ed40fe636d1c51336a1564ada79cf 247 SUPERFAMILY SSF55315 3 76 1.26E-16 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like HW35_10625 583ed40fe636d1c51336a1564ada79cf 247 SUPERFAMILY SSF75217 67 243 6.54E-50 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases HW35_07680 cba8853356eccb0cb951878675d1d8a4 225 SUPERFAMILY SSF56784 3 214 2.27E-61 T 12-10-2018 IPR036412 HAD-like superfamily HW35_07680 cba8853356eccb0cb951878675d1d8a4 225 Gene3D G3DSA:1.10.150.240 20 82 5.8E-53 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 HW35_07680 cba8853356eccb0cb951878675d1d8a4 225 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 87 177 1.1E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HW35_07680 cba8853356eccb0cb951878675d1d8a4 225 Hamap MF_01250 Pyrophosphatase PpaX [ppaX]. 3 216 43.995 T 12-10-2018 IPR023733 Pyrophosphatase PpaX GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HW35_07680 cba8853356eccb0cb951878675d1d8a4 225 Gene3D G3DSA:3.40.50.1000 8 187 5.8E-53 T 12-10-2018 IPR023214 HAD superfamily HW35_07680 cba8853356eccb0cb951878675d1d8a4 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 183 1.1E-54 T 12-10-2018 HW35_07680 cba8853356eccb0cb951878675d1d8a4 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 8.4E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HW35_07680 cba8853356eccb0cb951878675d1d8a4 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 8.4E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HW35_07680 cba8853356eccb0cb951878675d1d8a4 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 143 8.4E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HW35_07680 cba8853356eccb0cb951878675d1d8a4 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 8.4E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HW35_02915 10c27da33c832fe688b094f9a547724e 282 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 7 277 1.8E-87 T 12-10-2018 IPR003797 DegV HW35_02915 10c27da33c832fe688b094f9a547724e 282 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 278 1.2E-82 T 12-10-2018 IPR003797 DegV HW35_02915 10c27da33c832fe688b094f9a547724e 282 SUPERFAMILY SSF82549 3 278 1.94E-84 T 12-10-2018 HW35_02915 10c27da33c832fe688b094f9a547724e 282 Gene3D G3DSA:3.40.50.10170 2 152 8.5E-47 T 12-10-2018 HW35_02915 10c27da33c832fe688b094f9a547724e 282 Gene3D G3DSA:3.30.1180.10 153 279 7.3E-35 T 12-10-2018 HW35_04525 03db426fac7625378da825bcdfd55cea 249 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 10 247 5.6E-68 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 HW35_04525 03db426fac7625378da825bcdfd55cea 249 Gene3D G3DSA:3.40.1280.10 1 249 7.5E-91 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HW35_04525 03db426fac7625378da825bcdfd55cea 249 Pfam PF04452 RNA methyltransferase 16 243 4.2E-74 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 HW35_04525 03db426fac7625378da825bcdfd55cea 249 SUPERFAMILY SSF88697 2 67 2.39E-14 T 12-10-2018 IPR015947 PUA-like superfamily HW35_04525 03db426fac7625378da825bcdfd55cea 249 PIRSF PIRSF015601 1 247 2.0E-63 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 HW35_04525 03db426fac7625378da825bcdfd55cea 249 SUPERFAMILY SSF75217 71 247 9.16E-54 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases HW35_08835 8935779f78fd3e364792856476f28b9b 233 SUPERFAMILY SSF52540 48 226 1.28E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_08835 8935779f78fd3e364792856476f28b9b 233 Pfam PF13614 AAA domain 55 188 6.7E-15 T 12-10-2018 IPR025669 AAA domain HW35_08835 8935779f78fd3e364792856476f28b9b 233 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 29 231 8.9E-72 T 12-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 HW35_08835 8935779f78fd3e364792856476f28b9b 233 Gene3D G3DSA:3.40.50.300 2 233 6.3E-77 T 12-10-2018 HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 Pfam PF07702 UTRA domain 92 228 1.3E-33 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 Gene3D G3DSA:1.10.10.10 1 68 1.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 SMART SM00866 89 228 4.0E-27 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 SMART SM00345 8 67 3.4E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 4.9E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 4.9E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 8.0E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 SUPERFAMILY SSF64288 94 235 8.79E-42 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 Gene3D G3DSA:3.40.1410.10 87 227 8.7E-33 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 4 235 4.1E-91 T 12-10-2018 IPR012770 Trehalose operon transcriptional repressor HW35_00850 b5a369c1ca90f91a824bc88947d5b648 238 SUPERFAMILY SSF46785 3 71 7.29E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_03940 2b4e188dcffd5ddb58488ee138d94aff 432 Gene3D G3DSA:2.30.42.10 133 217 1.6E-15 T 12-10-2018 HW35_03940 2b4e188dcffd5ddb58488ee138d94aff 432 SUPERFAMILY SSF50494 346 415 6.51E-7 T 12-10-2018 IPR009003 Peptidase S1, PA clan HW35_03940 2b4e188dcffd5ddb58488ee138d94aff 432 Pfam PF05580 SpoIVB peptidase S55 208 416 5.8E-88 T 12-10-2018 IPR008763 Peptidase S55, SpoIVB HW35_03940 2b4e188dcffd5ddb58488ee138d94aff 432 SMART SM00228 122 191 7.2E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_03940 2b4e188dcffd5ddb58488ee138d94aff 432 Pfam PF13180 PDZ domain 137 193 5.6E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_03940 2b4e188dcffd5ddb58488ee138d94aff 432 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 9 421 1.5E-175 T 12-10-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B HW35_03940 2b4e188dcffd5ddb58488ee138d94aff 432 SUPERFAMILY SSF50156 141 223 9.73E-11 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 HW35_10660 a7a505dfbd86bde54b85bda8590e3993 164 Gene3D G3DSA:3.30.70.1730 2 162 4.5E-44 T 12-10-2018 HW35_10660 a7a505dfbd86bde54b85bda8590e3993 164 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 29.875 T 12-10-2018 IPR022973 Ribosomal protein L10 HW35_10660 a7a505dfbd86bde54b85bda8590e3993 164 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 12-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10660 a7a505dfbd86bde54b85bda8590e3993 164 Pfam PF00466 Ribosomal protein L10 6 101 4.4E-30 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 HW35_10660 a7a505dfbd86bde54b85bda8590e3993 164 SUPERFAMILY SSF160369 5 160 4.97E-56 T 12-10-2018 HW35_13940 78b9614a398f80f76215924470829b68 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 243 360 9.0E-15 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain HW35_13940 78b9614a398f80f76215924470829b68 394 SUPERFAMILY SSF56645 23 224 1.44E-40 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 HW35_13940 78b9614a398f80f76215924470829b68 394 SUPERFAMILY SSF47203 235 371 4.19E-23 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 HW35_13940 78b9614a398f80f76215924470829b68 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 216 2.1E-13 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 HW35_13940 78b9614a398f80f76215924470829b68 394 Gene3D G3DSA:1.20.140.10 235 376 1.2E-27 T 12-10-2018 HW35_13940 78b9614a398f80f76215924470829b68 394 Gene3D G3DSA:1.10.540.10 4 123 1.2E-18 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 HW35_13940 78b9614a398f80f76215924470829b68 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 96 7.7E-10 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 HW35_13940 78b9614a398f80f76215924470829b68 394 PIRSF PIRSF016578 3 107 6.5E-6 T 12-10-2018 HW35_13940 78b9614a398f80f76215924470829b68 394 PIRSF PIRSF016578 124 388 2.3E-23 T 12-10-2018 HW35_13940 78b9614a398f80f76215924470829b68 394 Gene3D G3DSA:2.40.110.10 134 224 2.9E-20 T 12-10-2018 HW35_13565 f3d12df4e743dbfb2e44b08f10ceabb7 233 SMART SM00419 173 222 3.8E-10 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_13565 f3d12df4e743dbfb2e44b08f10ceabb7 233 SMART SM00100 19 137 2.3E-20 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain HW35_13565 f3d12df4e743dbfb2e44b08f10ceabb7 233 Pfam PF13545 Crp-like helix-turn-helix domain 157 229 1.4E-16 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_13565 f3d12df4e743dbfb2e44b08f10ceabb7 233 SUPERFAMILY SSF46785 155 231 3.05E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13565 f3d12df4e743dbfb2e44b08f10ceabb7 233 SUPERFAMILY SSF51206 14 151 8.51E-36 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like HW35_13565 f3d12df4e743dbfb2e44b08f10ceabb7 233 Pfam PF00027 Cyclic nucleotide-binding domain 38 125 2.0E-20 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain HW35_13565 f3d12df4e743dbfb2e44b08f10ceabb7 233 Gene3D G3DSA:2.60.120.10 8 153 2.2E-36 T 12-10-2018 IPR014710 RmlC-like jelly roll fold HW35_13565 f3d12df4e743dbfb2e44b08f10ceabb7 233 Gene3D G3DSA:1.10.10.10 155 233 6.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_13565 f3d12df4e743dbfb2e44b08f10ceabb7 233 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 195 210 6.8E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_13565 f3d12df4e743dbfb2e44b08f10ceabb7 233 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 179 195 6.8E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 SMART SM00839 217 458 8.3E-97 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 134 147 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 Gene3D G3DSA:3.40.50.10860 67 202 4.3E-171 T 12-10-2018 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 215 458 2.2E-92 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 69 197 1.4E-51 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 Gene3D G3DSA:3.40.50.720 222 385 4.3E-171 T 12-10-2018 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 Gene3D G3DSA:1.10.285.10 18 393 4.3E-171 T 12-10-2018 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 248 268 8.3E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 126 140 8.3E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 384 395 8.3E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 206 228 8.3E-31 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 SUPERFAMILY SSF51735 215 459 1.97E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 SUPERFAMILY SSF53223 18 209 9.6E-78 T 12-10-2018 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 PIRSF PIRSF000185 32 460 5.0E-126 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 HW35_09585 ccbdd8a6eb84a7230a2813b2dafd2431 460 Gene3D G3DSA:1.10.285.10 394 460 2.7E-10 T 12-10-2018 HW35_05755 fe3687c950b6c563c5b0e2795ae67b59 365 SUPERFAMILY SSF53092 1 137 2.62E-35 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HW35_05755 fe3687c950b6c563c5b0e2795ae67b59 365 Pfam PF00557 Metallopeptidase family M24 147 347 2.5E-63 T 12-10-2018 IPR000994 Peptidase M24 HW35_05755 fe3687c950b6c563c5b0e2795ae67b59 365 SUPERFAMILY SSF55920 137 364 5.36E-79 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like HW35_05755 fe3687c950b6c563c5b0e2795ae67b59 365 Gene3D G3DSA:3.40.350.10 1 138 6.1E-40 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HW35_05755 fe3687c950b6c563c5b0e2795ae67b59 365 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 138 1.4E-28 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 HW35_05755 fe3687c950b6c563c5b0e2795ae67b59 365 Gene3D G3DSA:3.90.230.10 139 364 1.6E-80 T 12-10-2018 HW35_05755 fe3687c950b6c563c5b0e2795ae67b59 365 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site HW35_05755 fe3687c950b6c563c5b0e2795ae67b59 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 316 328 1.2E-6 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_05755 fe3687c950b6c563c5b0e2795ae67b59 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 218 234 1.2E-6 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_05755 fe3687c950b6c563c5b0e2795ae67b59 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 209 1.2E-6 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_16045 08c0033d4347e9b5316f5ca3d68fcdb6 196 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 38 152 2.4E-14 T 12-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like HW35_16045 08c0033d4347e9b5316f5ca3d68fcdb6 196 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 9 154 1.2E-38 T 12-10-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 2.0E-25 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 Gene3D G3DSA:3.30.1360.10 17 221 6.7E-90 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 1.6E-23 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 313 8.2E-127 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 Gene3D G3DSA:1.10.150.20 237 314 1.9E-34 T 12-10-2018 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 SUPERFAMILY SSF47789 247 313 7.85E-25 T 12-10-2018 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.385 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 Gene3D G3DSA:2.170.120.12 50 170 6.7E-90 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 1.9E-29 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 SUPERFAMILY SSF56553 50 171 6.28E-44 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 SMART SM00662 20 227 1.5E-106 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 SUPERFAMILY SSF55257 5 230 2.75E-32 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10845 3944cf3d1031c5fed0510429e032faba 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 152 2.4E-25 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_07020 56a3dcb7651476db67cd9a4151b515e2 100 SUPERFAMILY SSF102891 2 99 1.18E-33 T 12-10-2018 IPR036493 Hypothetical protein YunC superfamily HW35_07020 56a3dcb7651476db67cd9a4151b515e2 100 Pfam PF08827 Domain of unknown function (DUF1805) 37 99 4.4E-26 T 12-10-2018 IPR014931 Protein of unknown function DUF1805 HW35_07020 56a3dcb7651476db67cd9a4151b515e2 100 Gene3D G3DSA:3.30.1980.10 1 100 3.9E-25 T 12-10-2018 IPR036493 Hypothetical protein YunC superfamily HW35_16460 0c548d240e17f25b04f4e05653115065 434 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 335 355 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 HW35_16460 0c548d240e17f25b04f4e05653115065 434 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 13 413 6.8E-133 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 HW35_16460 0c548d240e17f25b04f4e05653115065 434 Pfam PF00860 Permease family 17 386 1.2E-111 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 HW35_04575 c6e38d274a4d13ae0f5b716f8895688e 372 SUPERFAMILY SSF53163 3 370 7.32E-132 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily HW35_04575 c6e38d274a4d13ae0f5b716f8895688e 372 Gene3D G3DSA:3.40.50.1450 292 371 2.2E-16 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily HW35_04575 c6e38d274a4d13ae0f5b716f8895688e 372 Gene3D G3DSA:3.40.50.1450 1 291 2.5E-112 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily HW35_04575 c6e38d274a4d13ae0f5b716f8895688e 372 TIGRFAM TIGR01441 GPR: GPR endopeptidase 10 368 1.7E-184 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HW35_04575 c6e38d274a4d13ae0f5b716f8895688e 372 Hamap MF_00626 Germination protease [gpr]. 1 372 158.295 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HW35_04575 c6e38d274a4d13ae0f5b716f8895688e 372 Pfam PF03418 Germination protease 17 370 3.7E-197 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HW35_04575 c6e38d274a4d13ae0f5b716f8895688e 372 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 10 371 2.0E-153 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HW35_04575 c6e38d274a4d13ae0f5b716f8895688e 372 PIRSF PIRSF019549 3 372 2.9E-185 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HW35_16115 41a13d417995fc4f4f47cdc5f58a242f 307 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 38 288 4.5E-59 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related HW35_16115 41a13d417995fc4f4f47cdc5f58a242f 307 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 11 289 3.5E-120 T 12-10-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG HW35_03590 8b3286acc2416c17508513c641037441 195 Pfam PF07670 Nucleoside recognition 43 150 1.4E-11 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HW35_14725 26b32346a86333c53b4d1d4711e82d53 415 Gene3D G3DSA:3.30.450.40 4 156 4.0E-6 T 12-10-2018 IPR029016 GAF-like domain superfamily HW35_14725 26b32346a86333c53b4d1d4711e82d53 415 Pfam PF13556 PucR C-terminal helix-turn-helix domain 348 406 1.5E-19 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain HW35_14725 26b32346a86333c53b4d1d4711e82d53 415 Gene3D G3DSA:1.10.10.2840 279 411 1.9E-18 T 12-10-2018 HW35_06390 45993380aaa29b02d4090dccf3be5dfd 268 Pfam PF00561 alpha/beta hydrolase fold 20 253 1.3E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_06390 45993380aaa29b02d4090dccf3be5dfd 268 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 10 267 36.163 T 12-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 HW35_06390 45993380aaa29b02d4090dccf3be5dfd 268 SUPERFAMILY SSF53474 4 266 1.22E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_06390 45993380aaa29b02d4090dccf3be5dfd 268 Gene3D G3DSA:3.40.50.1820 5 268 3.2E-66 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_06390 45993380aaa29b02d4090dccf3be5dfd 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 3.2E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_06390 45993380aaa29b02d4090dccf3be5dfd 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 3.2E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_06390 45993380aaa29b02d4090dccf3be5dfd 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 3.2E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_06390 45993380aaa29b02d4090dccf3be5dfd 268 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 20 266 2.2E-84 T 12-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 HW35_16815 4d153d29926c3382738086770e0f242f 374 SMART SM00322 302 356 1.7 T 12-10-2018 IPR004087 K Homology domain GO:0003676 HW35_16815 4d153d29926c3382738086770e0f242f 374 SMART SM00322 229 301 9.5E-4 T 12-10-2018 IPR004087 K Homology domain GO:0003676 HW35_16815 4d153d29926c3382738086770e0f242f 374 SMART SM00316 133 199 4.6E-12 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_16815 4d153d29926c3382738086770e0f242f 374 Gene3D G3DSA:3.30.1480.10 1 124 4.2E-50 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 HW35_16815 4d153d29926c3382738086770e0f242f 374 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 1.8E-130 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 HW35_16815 4d153d29926c3382738086770e0f242f 374 Gene3D G3DSA:2.40.50.140 136 197 1.5E-25 T 12-10-2018 HW35_16815 4d153d29926c3382738086770e0f242f 374 SUPERFAMILY SSF54814 278 341 1.44E-16 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 HW35_16815 4d153d29926c3382738086770e0f242f 374 Gene3D G3DSA:3.30.300.20 277 366 6.5E-33 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta HW35_16815 4d153d29926c3382738086770e0f242f 374 Pfam PF00575 S1 RNA binding domain 133 193 1.0E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 HW35_16815 4d153d29926c3382738086770e0f242f 374 SUPERFAMILY SSF69705 1 126 1.44E-43 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 HW35_16815 4d153d29926c3382738086770e0f242f 374 SUPERFAMILY SSF50249 132 198 4.48E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_16815 4d153d29926c3382738086770e0f242f 374 Pfam PF13184 NusA-like KH domain 229 296 4.8E-29 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 HW35_16815 4d153d29926c3382738086770e0f242f 374 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 362 30.902 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 HW35_16815 4d153d29926c3382738086770e0f242f 374 Gene3D G3DSA:3.30.300.20 198 276 1.6E-34 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta HW35_16815 4d153d29926c3382738086770e0f242f 374 SUPERFAMILY SSF54814 199 277 7.19E-31 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 HW35_16815 4d153d29926c3382738086770e0f242f 374 Pfam PF08529 NusA N-terminal domain 4 123 7.3E-45 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HW35_16865 b26c04829d678486a84a8bd3e1bfecc9 315 Pfam PF01522 Polysaccharide deacetylase 126 243 9.6E-30 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HW35_16865 b26c04829d678486a84a8bd3e1bfecc9 315 Gene3D G3DSA:3.20.20.370 115 315 1.4E-58 T 12-10-2018 HW35_16865 b26c04829d678486a84a8bd3e1bfecc9 315 SUPERFAMILY SSF88713 100 309 4.67E-60 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HW35_16865 b26c04829d678486a84a8bd3e1bfecc9 315 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 42 309 1.9E-131 T 12-10-2018 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY HW35_12995 6c97367cd10f0eab344e57a1c0d4c190 204 SUPERFAMILY SSF46689 9 78 8.21E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_12995 6c97367cd10f0eab344e57a1c0d4c190 204 Gene3D G3DSA:1.10.10.60 2 62 2.3E-14 T 12-10-2018 HW35_12995 6c97367cd10f0eab344e57a1c0d4c190 204 Gene3D G3DSA:1.10.357.10 63 204 1.2E-23 T 12-10-2018 HW35_12995 6c97367cd10f0eab344e57a1c0d4c190 204 SUPERFAMILY SSF48498 90 203 9.78E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily HW35_12995 6c97367cd10f0eab344e57a1c0d4c190 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 8.3E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_12995 6c97367cd10f0eab344e57a1c0d4c190 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 8.3E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_12995 6c97367cd10f0eab344e57a1c0d4c190 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 2.6E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_12995 6c97367cd10f0eab344e57a1c0d4c190 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HW35_14050 2412e9f9161ff2d688e33b78a59a4264 1227 SMART SM00926 45 107 3.6E-8 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_14050 2412e9f9161ff2d688e33b78a59a4264 1227 Pfam PF01568 Molydopterin dinucleotide binding domain 1076 1184 4.7E-18 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 HW35_14050 2412e9f9161ff2d688e33b78a59a4264 1227 Pfam PF00384 Molybdopterin oxidoreductase 110 821 1.5E-146 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_14050 2412e9f9161ff2d688e33b78a59a4264 1227 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1114 1141 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 HW35_14050 2412e9f9161ff2d688e33b78a59a4264 1227 SUPERFAMILY SSF50692 1068 1221 9.72E-43 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily HW35_14050 2412e9f9161ff2d688e33b78a59a4264 1227 Gene3D G3DSA:3.40.50.12440 46 1227 0.0 T 12-10-2018 HW35_14050 2412e9f9161ff2d688e33b78a59a4264 1227 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 50 68 - T 12-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 HW35_14050 2412e9f9161ff2d688e33b78a59a4264 1227 SUPERFAMILY SSF53706 27 1054 0.0 T 12-10-2018 HW35_14050 2412e9f9161ff2d688e33b78a59a4264 1227 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 6 1226 0.0 T 12-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 HW35_09910 a61cc1629ff17c38d9885fecf3e034b2 205 SUPERFAMILY SSF53163 12 197 1.86E-56 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily HW35_09910 a61cc1629ff17c38d9885fecf3e034b2 205 Pfam PF06866 Protein of unknown function (DUF1256) 18 180 2.7E-67 T 12-10-2018 IPR009665 Protein of unknown function DUF1256 HW35_09910 a61cc1629ff17c38d9885fecf3e034b2 205 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 42 181 1.1E-68 T 12-10-2018 IPR009665 Protein of unknown function DUF1256 HW35_05135 e14a83f0128093bd0bd1ec81519eab05 554 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 41 147 5.3E-25 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal HW35_05135 e14a83f0128093bd0bd1ec81519eab05 554 SUPERFAMILY SSF160246 2 143 3.01E-45 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily HW35_05135 e14a83f0128093bd0bd1ec81519eab05 554 Gene3D G3DSA:3.40.50.300 282 554 8.9E-116 T 12-10-2018 HW35_05135 e14a83f0128093bd0bd1ec81519eab05 554 SMART SM00382 308 431 0.0012 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_05135 e14a83f0128093bd0bd1ec81519eab05 554 Gene3D G3DSA:3.30.300.160 64 143 4.0E-18 T 12-10-2018 HW35_05135 e14a83f0128093bd0bd1ec81519eab05 554 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 375 389 - T 12-10-2018 IPR001482 Type II/IV secretion system protein HW35_05135 e14a83f0128093bd0bd1ec81519eab05 554 SUPERFAMILY SSF52540 168 553 1.39E-98 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05135 e14a83f0128093bd0bd1ec81519eab05 554 Gene3D G3DSA:3.30.450.90 144 280 1.6E-47 T 12-10-2018 HW35_05135 e14a83f0128093bd0bd1ec81519eab05 554 Pfam PF00437 Type II/IV secretion system protein 182 447 1.9E-83 T 12-10-2018 IPR001482 Type II/IV secretion system protein HW35_11185 e7e92c0759d764726834826657d97c02 441 Pfam PF02378 Phosphotransferase system, EIIC 31 363 3.2E-46 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HW35_11185 e7e92c0759d764726834826657d97c02 441 PIRSF PIRSF006351 2 441 2.5E-133 T 12-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 HW35_11185 e7e92c0759d764726834826657d97c02 441 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 16 433 2.1E-107 T 12-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 HW35_09555 66293510d4d5b878121621f3f69307a0 618 Pfam PF00664 ABC transporter transmembrane region 55 329 4.0E-65 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 HW35_09555 66293510d4d5b878121621f3f69307a0 618 SMART SM00382 400 586 6.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_09555 66293510d4d5b878121621f3f69307a0 618 SUPERFAMILY SSF52540 365 610 3.94E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09555 66293510d4d5b878121621f3f69307a0 618 Gene3D G3DSA:1.20.1560.10 27 361 8.5E-112 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_09555 66293510d4d5b878121621f3f69307a0 618 Pfam PF00005 ABC transporter 391 540 1.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_09555 66293510d4d5b878121621f3f69307a0 618 SUPERFAMILY SSF90123 38 361 1.7E-91 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_09555 66293510d4d5b878121621f3f69307a0 618 Gene3D G3DSA:3.40.50.300 371 617 6.5E-89 T 12-10-2018 HW35_09555 66293510d4d5b878121621f3f69307a0 618 ProSitePatterns PS00211 ABC transporters family signature. 512 526 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_09245 d3ca7d36a031999733ed626956aac7de 531 Pfam PF00117 Glutamine amidotransferase class-I 302 527 5.7E-61 T 12-10-2018 IPR017926 Glutamine amidotransferase HW35_09245 d3ca7d36a031999733ed626956aac7de 531 Pfam PF06418 CTP synthase N-terminus 3 267 1.3E-132 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 HW35_09245 d3ca7d36a031999733ed626956aac7de 531 SUPERFAMILY SSF52317 290 529 1.38E-87 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_09245 d3ca7d36a031999733ed626956aac7de 531 Gene3D G3DSA:3.40.50.880 286 531 1.4E-105 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_09245 d3ca7d36a031999733ed626956aac7de 531 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 7.2E-268 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 HW35_09245 d3ca7d36a031999733ed626956aac7de 531 SUPERFAMILY SSF52540 1 270 1.14E-128 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09245 d3ca7d36a031999733ed626956aac7de 531 Gene3D G3DSA:3.40.50.300 1 285 2.1E-138 T 12-10-2018 HW35_09245 d3ca7d36a031999733ed626956aac7de 531 Hamap MF_01227 CTP synthase [pyrG]. 2 531 52.943 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 HW35_07880 e355da5c9d2e5d188b380638dc089b9d 180 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 4.8E-35 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 HW35_07880 e355da5c9d2e5d188b380638dc089b9d 180 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 95 4.2E-31 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 HW35_07880 e355da5c9d2e5d188b380638dc089b9d 180 SUPERFAMILY SSF69754 1 103 6.41E-34 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like HW35_07880 e355da5c9d2e5d188b380638dc089b9d 180 Gene3D G3DSA:3.30.160.100 2 102 1.6E-33 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like HW35_07880 e355da5c9d2e5d188b380638dc089b9d 180 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 120 176 2.0E-29 T 12-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal HW35_07880 e355da5c9d2e5d188b380638dc089b9d 180 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 180 24.989 T 12-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid HW35_07880 e355da5c9d2e5d188b380638dc089b9d 180 Gene3D G3DSA:3.30.505.50 134 179 2.0E-26 T 12-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily HW35_08980 0b7a88dd91f741c231e16f52b15885ee 404 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 79 1.2E-11 T 12-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HW35_08980 0b7a88dd91f741c231e16f52b15885ee 404 Pfam PF01610 Transposase 150 390 1.0E-70 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HW35_09590 0b7a88dd91f741c231e16f52b15885ee 404 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 79 1.2E-11 T 12-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HW35_09590 0b7a88dd91f741c231e16f52b15885ee 404 Pfam PF01610 Transposase 150 390 1.0E-70 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HW35_13115 0b7a88dd91f741c231e16f52b15885ee 404 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 79 1.2E-11 T 12-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HW35_13115 0b7a88dd91f741c231e16f52b15885ee 404 Pfam PF01610 Transposase 150 390 1.0E-70 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HW35_14510 0b7a88dd91f741c231e16f52b15885ee 404 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 79 1.2E-11 T 12-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HW35_14510 0b7a88dd91f741c231e16f52b15885ee 404 Pfam PF01610 Transposase 150 390 1.0E-70 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HW35_06745 ca21b712677b5d6e17cfab91b2c31ba3 251 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 89 117 2.1E-10 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 HW35_06745 ca21b712677b5d6e17cfab91b2c31ba3 251 SUPERFAMILY SSF57716 91 119 1.71E-6 T 12-10-2018 HW35_06745 ca21b712677b5d6e17cfab91b2c31ba3 251 Gene3D G3DSA:1.20.120.910 1 128 1.9E-30 T 12-10-2018 HW35_06745 ca21b712677b5d6e17cfab91b2c31ba3 251 SUPERFAMILY SSF109635 2 90 3.79E-13 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily HW35_06745 ca21b712677b5d6e17cfab91b2c31ba3 251 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 5 165 3.1E-60 T 12-10-2018 IPR014240 Regulatory protein, YteA family HW35_09070 ec4a32d3805ab61417fdcdf682a37d57 170 Gene3D G3DSA:3.40.50.12280 5 170 1.1E-76 T 12-10-2018 HW35_09070 ec4a32d3805ab61417fdcdf682a37d57 170 SUPERFAMILY SSF56770 18 163 1.31E-65 T 12-10-2018 HW35_09070 ec4a32d3805ab61417fdcdf682a37d57 170 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 19 161 1.3E-71 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09070 ec4a32d3805ab61417fdcdf682a37d57 170 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 9 160 42.036 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09070 ec4a32d3805ab61417fdcdf682a37d57 170 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 46 155 2.9E-25 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_06595 0e5096f51bb9135053ba6146779c9168 356 Gene3D G3DSA:3.40.50.1100 13 323 2.2E-124 T 12-10-2018 HW35_06595 0e5096f51bb9135053ba6146779c9168 356 TIGRFAM TIGR00260 thrC: threonine synthase 9 323 1.5E-103 T 12-10-2018 IPR004450 Threonine synthase-like HW35_06595 0e5096f51bb9135053ba6146779c9168 356 SUPERFAMILY SSF53686 3 328 3.93E-106 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HW35_06595 0e5096f51bb9135053ba6146779c9168 356 PIRSF PIRSF038945 1 348 2.8E-162 T 12-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 HW35_06595 0e5096f51bb9135053ba6146779c9168 356 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 316 2.6E-79 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HW35_06595 0e5096f51bb9135053ba6146779c9168 356 Gene3D G3DSA:3.40.50.1100 59 155 2.2E-124 T 12-10-2018 HW35_06595 0e5096f51bb9135053ba6146779c9168 356 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 HW35_15140 9499b00ae6095a97ac29078265ef37c1 419 SUPERFAMILY SSF56672 15 356 2.06E-62 T 12-10-2018 HW35_15140 9499b00ae6095a97ac29078265ef37c1 419 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 4.0E-134 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_15140 9499b00ae6095a97ac29078265ef37c1 419 Pfam PF08388 Group II intron, maturase-specific domain 288 360 6.7E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_15140 9499b00ae6095a97ac29078265ef37c1 419 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 1.7E-47 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_15140 9499b00ae6095a97ac29078265ef37c1 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_15140 9499b00ae6095a97ac29078265ef37c1 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_15140 9499b00ae6095a97ac29078265ef37c1 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_14100 e1dc6f368f1b716562af43fde26e38bc 538 Gene3D G3DSA:3.90.76.10 61 213 2.0E-184 T 12-10-2018 HW35_14100 e1dc6f368f1b716562af43fde26e38bc 538 PIRSF PIRSF002741 4 538 7.9E-155 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HW35_14100 e1dc6f368f1b716562af43fde26e38bc 538 Gene3D G3DSA:3.10.105.10 296 513 2.0E-184 T 12-10-2018 HW35_14100 e1dc6f368f1b716562af43fde26e38bc 538 Gene3D G3DSA:3.40.190.10 214 526 2.0E-184 T 12-10-2018 HW35_14100 e1dc6f368f1b716562af43fde26e38bc 538 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 457 2.7E-124 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain HW35_14100 e1dc6f368f1b716562af43fde26e38bc 538 SUPERFAMILY SSF53850 43 537 4.97E-169 T 12-10-2018 HW35_14100 e1dc6f368f1b716562af43fde26e38bc 538 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 95 117 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 PRINTS PR00625 DnaJ domain signature 61 80 2.8E-30 T 12-10-2018 IPR001623 DnaJ domain HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 PRINTS PR00625 DnaJ domain signature 7 25 2.8E-30 T 12-10-2018 IPR001623 DnaJ domain HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 PRINTS PR00625 DnaJ domain signature 25 40 2.8E-30 T 12-10-2018 IPR001623 DnaJ domain HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 PRINTS PR00625 DnaJ domain signature 41 61 2.8E-30 T 12-10-2018 IPR001623 DnaJ domain HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 Gene3D G3DSA:1.10.287.110 1 109 1.7E-39 T 12-10-2018 IPR036869 Chaperone J-domain superfamily HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 Gene3D G3DSA:2.10.230.10 145 209 7.4E-37 T 12-10-2018 HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 Pfam PF01556 DnaJ C terminal domain 118 335 6.1E-46 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 Pfam PF00684 DnaJ central domain 145 209 2.4E-13 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 372 42.283 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 SUPERFAMILY SSF49493 260 346 4.06E-26 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 Pfam PF00226 DnaJ domain 5 66 1.3E-27 T 12-10-2018 IPR001623 DnaJ domain HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 SMART SM00271 4 61 1.5E-31 T 12-10-2018 IPR001623 DnaJ domain HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 Gene3D G3DSA:2.60.260.20 115 251 7.4E-37 T 12-10-2018 HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 SUPERFAMILY SSF46565 1 102 9.29E-37 T 12-10-2018 IPR036869 Chaperone J-domain superfamily HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 352 6.5E-146 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 12-10-2018 IPR018253 DnaJ domain, conserved site HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 SUPERFAMILY SSF49493 112 259 1.83E-20 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 SUPERFAMILY SSF57938 132 213 5.1E-19 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily HW35_04535 8fed1cce32f7befd27b0bb5565722aed 376 Gene3D G3DSA:2.60.260.20 256 358 2.7E-31 T 12-10-2018 HW35_00095 8f84f14a29967bf55a23f033bddb5e1b 488 SMART SM00382 26 216 1.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_00095 8f84f14a29967bf55a23f033bddb5e1b 488 Pfam PF01955 Adenosylcobinamide amidohydrolase 287 474 1.2E-54 T 12-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ HW35_00095 8f84f14a29967bf55a23f033bddb5e1b 488 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_00095 8f84f14a29967bf55a23f033bddb5e1b 488 Gene3D G3DSA:3.40.50.300 1 256 3.8E-71 T 12-10-2018 HW35_00095 8f84f14a29967bf55a23f033bddb5e1b 488 SUPERFAMILY SSF52540 2 232 1.41E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_00095 8f84f14a29967bf55a23f033bddb5e1b 488 Pfam PF00005 ABC transporter 17 167 3.9E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_14075 873f411bd7a07c6a2f3aca5b329567e8 309 Pfam PF04960 Glutaminase 23 309 1.7E-114 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 HW35_14075 873f411bd7a07c6a2f3aca5b329567e8 309 Hamap MF_00313 Glutaminase [glsA]. 5 309 47.011 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 HW35_14075 873f411bd7a07c6a2f3aca5b329567e8 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 9 309 8.7E-125 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 HW35_14075 873f411bd7a07c6a2f3aca5b329567e8 309 Gene3D G3DSA:3.40.710.10 3 309 7.6E-116 T 12-10-2018 HW35_14075 873f411bd7a07c6a2f3aca5b329567e8 309 SUPERFAMILY SSF56601 8 309 6.1E-115 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 Gene3D G3DSA:3.30.50.30 3 50 8.3E-22 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 Gene3D G3DSA:3.40.50.300 53 309 1.7E-108 T 12-10-2018 HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 SMART SM01086 311 405 3.2E-34 T 12-10-2018 IPR019489 Clp ATPase, C-terminal HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 Pfam PF06689 ClpX C4-type zinc finger 12 48 2.6E-20 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 SUPERFAMILY SSF57716 11 46 1.71E-11 T 12-10-2018 HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 SMART SM00994 10 49 8.0E-24 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 409 54.208 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 6 406 2.7E-215 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 7.1E-19 T 12-10-2018 IPR019489 Clp ATPase, C-terminal HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 SMART SM00382 108 269 3.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 1.4E-51 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 SUPERFAMILY SSF52540 59 397 8.46E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05265 f7799cb8b7360a94e3499a47996a7c3e 419 Gene3D G3DSA:1.10.8.60 310 418 3.0E-39 T 12-10-2018 HW35_09905 9808a8b92583187ab0034e58414413e7 287 SUPERFAMILY SSF50182 113 173 1.11E-15 T 12-10-2018 IPR010920 LSM domain superfamily HW35_09905 9808a8b92583187ab0034e58414413e7 287 Gene3D G3DSA:3.30.70.100 178 265 4.8E-23 T 12-10-2018 HW35_09905 9808a8b92583187ab0034e58414413e7 287 SUPERFAMILY SSF82861 23 111 2.35E-15 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 HW35_09905 9808a8b92583187ab0034e58414413e7 287 SUPERFAMILY SSF82689 178 277 2.62E-15 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 HW35_09905 9808a8b92583187ab0034e58414413e7 287 Gene3D G3DSA:2.30.30.60 128 176 2.4E-23 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily HW35_09905 9808a8b92583187ab0034e58414413e7 287 Pfam PF00924 Mechanosensitive ion channel 70 267 7.1E-48 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 HW35_15685 5eb3a63d51962369153dcc93c1b21fdb 404 SUPERFAMILY SSF54966 1 111 4.85E-29 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 HW35_15685 5eb3a63d51962369153dcc93c1b21fdb 404 SUPERFAMILY SSF51649 111 401 3.53E-86 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 HW35_15685 5eb3a63d51962369153dcc93c1b21fdb 404 Gene3D G3DSA:3.20.20.110 112 402 1.3E-99 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 HW35_15685 5eb3a63d51962369153dcc93c1b21fdb 404 Gene3D G3DSA:3.30.70.150 1 111 5.4E-30 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 HW35_15685 5eb3a63d51962369153dcc93c1b21fdb 404 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 117 396 9.3E-41 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 HW35_15685 5eb3a63d51962369153dcc93c1b21fdb 404 Hamap MF_01679 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [mtnW]. 2 397 58.815 T 12-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 HW35_15685 5eb3a63d51962369153dcc93c1b21fdb 404 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2 397 8.5E-205 T 12-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 HW35_15685 5eb3a63d51962369153dcc93c1b21fdb 404 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 3 91 7.1E-7 T 12-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 Gene3D G3DSA:3.30.70.3280 388 524 3.2E-46 T 12-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 SUPERFAMILY SSF54980 391 462 7.19E-16 T 12-10-2018 IPR035647 EF-G domain III/V-like HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 Gene3D G3DSA:3.40.50.300 109 272 9.0E-101 T 12-10-2018 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 Gene3D G3DSA:3.40.50.300 71 376 9.0E-101 T 12-10-2018 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 Pfam PF00009 Elongation factor Tu GTP binding domain 13 274 2.8E-50 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 3 522 49.525 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 PRINTS PR00315 GTP-binding elongation factor signature 64 72 3.6E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.6E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.6E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.6E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.6E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 5 520 1.3E-202 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 SUPERFAMILY SSF50447 258 386 2.29E-26 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 Pfam PF03144 Elongation factor Tu domain 2 311 377 2.0E-9 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 Pfam PF16658 Class II release factor RF3, C-terminal domain 385 510 7.6E-43 T 12-10-2018 IPR032090 Peptide chain release factor 3, C-terminal HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 SUPERFAMILY SSF52540 12 274 3.2E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15620 bcbd5bd354dcf42a9f3213ee777774ff 526 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 16 149 3.3E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_14275 737618200b21c909d348ae436ce330f6 356 Pfam PF06081 Aromatic acid exporter family member 1 1 142 4.7E-42 T 12-10-2018 IPR010343 Aromatic acid exporter family member 1 HW35_04400 bccea77323b159110580a5d54be147a9 242 SUPERFAMILY SSF53335 11 105 2.38E-10 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_04400 bccea77323b159110580a5d54be147a9 242 Gene3D G3DSA:3.40.50.150 1 163 9.2E-60 T 12-10-2018 HW35_04400 bccea77323b159110580a5d54be147a9 242 PIRSF PIRSF018637 4 237 4.3E-86 T 12-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 HW35_04400 bccea77323b159110580a5d54be147a9 242 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 231 1.3E-74 T 12-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 HW35_01470 5eb7d9a51229a97390ec177432644688 310 PIRSF PIRSF016080 14 307 1.7E-98 T 12-10-2018 IPR021191 Restriction endonuclease, type II, DpmII GO:0003677|GO:0009036|GO:0009307 HW35_01470 5eb7d9a51229a97390ec177432644688 310 Pfam PF04556 DpnII restriction endonuclease 20 303 1.6E-98 T 12-10-2018 IPR007637 Restriction endonuclease, type II, DpmII-like GO:0003677|GO:0009036|GO:0009307 HW35_02930 abcfcea5808200096d4d834b341fc09a 302 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 299 42.224 T 12-10-2018 IPR033752 MetA family HW35_02930 abcfcea5808200096d4d834b341fc09a 302 Gene3D G3DSA:3.40.50.880 1 300 1.8E-126 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_02930 abcfcea5808200096d4d834b341fc09a 302 Pfam PF04204 Homoserine O-succinyltransferase 2 299 5.8E-138 T 12-10-2018 IPR033752 MetA family HW35_02930 abcfcea5808200096d4d834b341fc09a 302 PIRSF PIRSF000450 1 302 1.6E-147 T 12-10-2018 IPR033752 MetA family HW35_02930 abcfcea5808200096d4d834b341fc09a 302 SUPERFAMILY SSF52317 17 297 1.02E-98 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_02930 abcfcea5808200096d4d834b341fc09a 302 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 2.0E-98 T 12-10-2018 HW35_02930 abcfcea5808200096d4d834b341fc09a 302 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 300 1.5E-136 T 12-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 1.1E-186 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 1.1E-27 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 Gene3D G3DSA:1.10.40.30 349 432 1.5E-36 T 12-10-2018 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 Gene3D G3DSA:1.20.200.10 93 348 2.5E-104 T 12-10-2018 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 Pfam PF00206 Lyase 6 286 9.4E-80 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 SMART SM00998 349 429 7.0E-43 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 2.1E-26 T 12-10-2018 IPR000362 Fumarate lyase family HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 2.1E-26 T 12-10-2018 IPR000362 Fumarate lyase family HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 2.1E-26 T 12-10-2018 IPR000362 Fumarate lyase family HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 2.1E-26 T 12-10-2018 IPR000362 Fumarate lyase family HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 Gene3D G3DSA:1.10.275.10 1 92 1.4E-40 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 7.1E-10 T 12-10-2018 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 7.1E-10 T 12-10-2018 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 7.1E-10 T 12-10-2018 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 7.1E-10 T 12-10-2018 HW35_11690 86aa43bce479a62ceca4b8a7c0606d06 432 SUPERFAMILY SSF48557 3 427 7.7E-143 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 HW35_15130 0b85696d081de0f3b3706177018e8d5d 287 PIRSF PIRSF012524 3 286 2.5E-101 T 12-10-2018 IPR014464 Conserved virulence factor B HW35_15130 0b85696d081de0f3b3706177018e8d5d 287 Gene3D G3DSA:2.40.50.140 75 152 9.6E-26 T 12-10-2018 HW35_15130 0b85696d081de0f3b3706177018e8d5d 287 Gene3D G3DSA:1.10.10.10 223 284 3.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_15130 0b85696d081de0f3b3706177018e8d5d 287 Gene3D G3DSA:2.40.50.140 155 221 1.1E-18 T 12-10-2018 HW35_15130 0b85696d081de0f3b3706177018e8d5d 287 Pfam PF13509 S1 domain 7 65 2.5E-21 T 12-10-2018 IPR039566 Conserved virulence factor B, S1 domain HW35_15130 0b85696d081de0f3b3706177018e8d5d 287 SMART SM00316 71 137 28.0 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_15130 0b85696d081de0f3b3706177018e8d5d 287 SMART SM00316 6 66 1.1 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_15130 0b85696d081de0f3b3706177018e8d5d 287 SMART SM00316 153 215 3.4 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_03575 7076b1f1c855188a6def35ff1e63e1b2 174 SUPERFAMILY SSF52833 36 172 9.09E-48 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_03575 7076b1f1c855188a6def35ff1e63e1b2 174 Gene3D G3DSA:3.40.30.10 25 173 2.6E-50 T 12-10-2018 HW35_03575 7076b1f1c855188a6def35ff1e63e1b2 174 ProSitePatterns PS00194 Thioredoxin family active site. 66 84 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 HW35_03575 7076b1f1c855188a6def35ff1e63e1b2 174 Pfam PF00578 AhpC/TSA family 38 153 4.0E-38 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HW35_15390 2526c8698e9f76c051a134ad3906c7c6 264 SUPERFAMILY SSF111331 16 261 8.11E-63 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily HW35_15390 2526c8698e9f76c051a134ad3906c7c6 264 Gene3D G3DSA:3.40.50.10330 18 262 1.6E-99 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 HW35_15390 2526c8698e9f76c051a134ad3906c7c6 264 Pfam PF01513 ATP-NAD kinase 32 186 2.4E-23 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HW35_15390 2526c8698e9f76c051a134ad3906c7c6 264 Hamap MF_00361 NAD kinase [nadK]. 1 263 23.535 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HW35_15390 2526c8698e9f76c051a134ad3906c7c6 264 Gene3D G3DSA:2.60.200.30 102 240 1.6E-99 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 SUPERFAMILY SSF63411 4 151 1.28E-60 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 PIRSF PIRSF006160 1 157 4.6E-63 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 157 33.589 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 145 5.0E-73 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 119 138 1.9E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 1.9E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 1.9E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 78 96 1.9E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 1.9E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 Gene3D G3DSA:3.30.1360.80 1 157 9.1E-63 T 12-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_06350 e2eb7549ef72fbe240ce723fe6240c21 157 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 152 3.1E-52 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HW35_15510 09088c83e22c52e51fdb7e8a16182918 145 SUPERFAMILY SSF46689 28 129 1.18E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_15810 09088c83e22c52e51fdb7e8a16182918 145 SUPERFAMILY SSF46689 28 129 1.18E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_07955 09088c83e22c52e51fdb7e8a16182918 145 SUPERFAMILY SSF46689 28 129 1.18E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_02940 09088c83e22c52e51fdb7e8a16182918 145 SUPERFAMILY SSF46689 28 129 1.18E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_05330 09088c83e22c52e51fdb7e8a16182918 145 SUPERFAMILY SSF46689 28 129 1.18E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 Gene3D G3DSA:3.40.50.200 114 308 3.0E-56 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 132 143 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 462 472 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 Pfam PF02225 PA domain 334 400 1.3E-12 T 12-10-2018 IPR003137 PA domain HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 Pfam PF00082 Subtilase family 127 538 5.5E-75 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 175 185 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 Gene3D G3DSA:3.50.30.30 309 412 3.2E-24 T 12-10-2018 HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 Gene3D G3DSA:2.60.40.10 563 647 4.8E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 Gene3D G3DSA:3.40.50.200 413 553 1.1E-35 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 SUPERFAMILY SSF52743 122 548 6.94E-90 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 SUPERFAMILY SSF52025 321 407 1.83E-15 T 12-10-2018 HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 PRINTS PR00723 Subtilisin serine protease family (S8) signature 461 477 7.1E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 PRINTS PR00723 Subtilisin serine protease family (S8) signature 171 184 7.1E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_09135 cf88116c905e51b553d1f7748d6c1b28 752 PRINTS PR00723 Subtilisin serine protease family (S8) signature 127 146 7.1E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_01240 0779450a3c8767187f3e461e904eb780 378 Pfam PF14504 CAP-associated N-terminal 105 241 4.5E-33 T 12-10-2018 IPR029410 CAP-associated domain HW35_01240 0779450a3c8767187f3e461e904eb780 378 Gene3D G3DSA:3.40.33.10 71 377 1.5E-69 T 12-10-2018 IPR035940 CAP superfamily HW35_01240 0779450a3c8767187f3e461e904eb780 378 Pfam PF00188 Cysteine-rich secretory protein family 259 375 3.6E-12 T 12-10-2018 IPR014044 CAP domain HW35_01240 0779450a3c8767187f3e461e904eb780 378 SUPERFAMILY SSF55797 254 376 1.96E-24 T 12-10-2018 IPR035940 CAP superfamily HW35_04270 34bba20372aaa52eddb69cc9fc9969f7 49 Gene3D G3DSA:2.20.28.120 1 49 1.5E-24 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04270 34bba20372aaa52eddb69cc9fc9969f7 49 Pfam PF00471 Ribosomal protein L33 3 49 2.7E-23 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04270 34bba20372aaa52eddb69cc9fc9969f7 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 3.4E-21 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04270 34bba20372aaa52eddb69cc9fc9969f7 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.721 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04270 34bba20372aaa52eddb69cc9fc9969f7 49 SUPERFAMILY SSF57829 1 49 1.65E-19 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 HW35_04270 34bba20372aaa52eddb69cc9fc9969f7 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 12-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_14320 8f00b004a2410edfb4b4bcf5ee27aab0 150 Pfam PF01475 Ferric uptake regulator family 15 133 2.7E-41 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 HW35_14320 8f00b004a2410edfb4b4bcf5ee27aab0 150 SUPERFAMILY SSF46785 8 138 2.73E-42 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_14320 8f00b004a2410edfb4b4bcf5ee27aab0 150 Gene3D G3DSA:1.10.10.10 1 87 3.2E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_14320 8f00b004a2410edfb4b4bcf5ee27aab0 150 Gene3D G3DSA:3.30.1490.190 88 145 2.8E-24 T 12-10-2018 HW35_15060 3594e67503076dab13da9aac4bafa40b 184 Pfam PF00717 Peptidase S24-like 36 103 1.1E-20 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HW35_15060 3594e67503076dab13da9aac4bafa40b 184 ProSitePatterns PS00761 Signal peptidases I signature 3. 142 155 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 HW35_15060 3594e67503076dab13da9aac4bafa40b 184 ProSitePatterns PS00760 Signal peptidases I lysine active site. 81 93 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 HW35_15060 3594e67503076dab13da9aac4bafa40b 184 SUPERFAMILY SSF51306 27 181 2.96E-53 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily HW35_15060 3594e67503076dab13da9aac4bafa40b 184 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 HW35_15060 3594e67503076dab13da9aac4bafa40b 184 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 177 1.4E-53 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HW35_15060 3594e67503076dab13da9aac4bafa40b 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 91 1.0E-21 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HW35_15060 3594e67503076dab13da9aac4bafa40b 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 1.0E-21 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HW35_15060 3594e67503076dab13da9aac4bafa40b 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 1.0E-21 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HW35_15060 3594e67503076dab13da9aac4bafa40b 184 Gene3D G3DSA:2.10.109.10 59 184 1.2E-47 T 12-10-2018 HW35_03935 7fd5a36780e3d3418a97fe25a44f020d 264 SMART SM00448 4 119 1.2E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_03935 7fd5a36780e3d3418a97fe25a44f020d 264 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 153 263 3.0E-58 T 12-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 HW35_03935 7fd5a36780e3d3418a97fe25a44f020d 264 Gene3D G3DSA:3.40.50.2300 1 145 5.4E-33 T 12-10-2018 HW35_03935 7fd5a36780e3d3418a97fe25a44f020d 264 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 2 264 4.3E-130 T 12-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 HW35_03935 7fd5a36780e3d3418a97fe25a44f020d 264 SUPERFAMILY SSF46894 148 262 1.62E-48 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_03935 7fd5a36780e3d3418a97fe25a44f020d 264 PIRSF PIRSF002937 1 264 1.6E-132 T 12-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 HW35_03935 7fd5a36780e3d3418a97fe25a44f020d 264 SUPERFAMILY SSF52172 2 145 6.97E-33 T 12-10-2018 IPR011006 CheY-like superfamily HW35_03935 7fd5a36780e3d3418a97fe25a44f020d 264 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 154 257 3.7E-45 T 12-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 HW35_03935 7fd5a36780e3d3418a97fe25a44f020d 264 Gene3D G3DSA:1.10.10.10 146 264 6.5E-55 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_03935 7fd5a36780e3d3418a97fe25a44f020d 264 Pfam PF00072 Response regulator receiver domain 6 119 8.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_00615 b1394c9d9a04070094819d41859c1b2e 495 Gene3D G3DSA:1.10.10.60 388 443 1.0E-11 T 12-10-2018 HW35_00615 b1394c9d9a04070094819d41859c1b2e 495 SUPERFAMILY SSF46689 442 490 2.11E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_00615 b1394c9d9a04070094819d41859c1b2e 495 Gene3D G3DSA:1.10.10.2730 444 489 1.2E-18 T 12-10-2018 HW35_00615 b1394c9d9a04070094819d41859c1b2e 495 SUPERFAMILY SSF52172 6 128 6.01E-12 T 12-10-2018 IPR011006 CheY-like superfamily HW35_00615 b1394c9d9a04070094819d41859c1b2e 495 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 458 473 1.4E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HW35_00615 b1394c9d9a04070094819d41859c1b2e 495 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 473 489 1.4E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HW35_00615 b1394c9d9a04070094819d41859c1b2e 495 Gene3D G3DSA:3.40.50.2300 4 137 2.1E-10 T 12-10-2018 HW35_00615 b1394c9d9a04070094819d41859c1b2e 495 SMART SM00342 406 489 7.1E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HW35_00615 b1394c9d9a04070094819d41859c1b2e 495 Pfam PF12833 Helix-turn-helix domain 413 489 1.9E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HW35_16265 852b52c9f9c426a349d958afefda58d5 301 Gene3D G3DSA:3.40.50.720 1 172 2.5E-47 T 12-10-2018 HW35_16265 852b52c9f9c426a349d958afefda58d5 301 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 2.9E-22 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain HW35_16265 852b52c9f9c426a349d958afefda58d5 301 SUPERFAMILY SSF48179 173 293 5.1E-27 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_16265 852b52c9f9c426a349d958afefda58d5 301 Gene3D G3DSA:1.10.1040.10 173 300 3.9E-42 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HW35_16265 852b52c9f9c426a349d958afefda58d5 301 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 174 293 2.1E-30 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain HW35_16265 852b52c9f9c426a349d958afefda58d5 301 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 294 4.3E-65 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 HW35_16265 852b52c9f9c426a349d958afefda58d5 301 SUPERFAMILY SSF51735 1 160 1.05E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_11725 819360dac228a16b5d775efab9e1c334 200 SUPERFAMILY SSF53328 3 189 1.06E-57 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HW35_11725 819360dac228a16b5d775efab9e1c334 200 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 31.129 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 HW35_11725 819360dac228a16b5d775efab9e1c334 200 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 188 1.1E-70 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 HW35_11725 819360dac228a16b5d775efab9e1c334 200 Gene3D G3DSA:3.40.50.170 1 199 1.2E-74 T 12-10-2018 HW35_11725 819360dac228a16b5d775efab9e1c334 200 Pfam PF00551 Formyl transferase 2 181 3.4E-58 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HW35_11725 819360dac228a16b5d775efab9e1c334 200 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HW35_10300 6e36813dba0307be9930d1bc26710b88 488 Gene3D G3DSA:1.10.287.1080 356 487 1.6E-44 T 12-10-2018 HW35_10300 6e36813dba0307be9930d1bc26710b88 488 TIGRFAM TIGR00444 mazG: MazG family protein 239 484 3.1E-104 T 12-10-2018 IPR011551 NTP pyrophosphohydrolase MazG HW35_10300 6e36813dba0307be9930d1bc26710b88 488 PIRSF PIRSF002845 1 487 2.3E-221 T 12-10-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted HW35_10300 6e36813dba0307be9930d1bc26710b88 488 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 255 328 4.2E-30 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core HW35_10300 6e36813dba0307be9930d1bc26710b88 488 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 393 453 1.5E-5 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core HW35_10300 6e36813dba0307be9930d1bc26710b88 488 SUPERFAMILY SSF53790 4 263 7.41E-30 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 HW35_10300 6e36813dba0307be9930d1bc26710b88 488 SUPERFAMILY SSF101386 231 332 2.29E-26 T 12-10-2018 HW35_10300 6e36813dba0307be9930d1bc26710b88 488 SUPERFAMILY SSF101386 363 464 9.91E-23 T 12-10-2018 HW35_10300 6e36813dba0307be9930d1bc26710b88 488 Gene3D G3DSA:1.10.287.1080 229 352 2.6E-45 T 12-10-2018 HW35_10300 6e36813dba0307be9930d1bc26710b88 488 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 206 1.2E-23 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 HW35_10300 6e36813dba0307be9930d1bc26710b88 488 Gene3D G3DSA:3.40.1010.10 2 119 1.7E-9 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 HW35_16555 29f6dd8cd17ea625a5cb67da243c4711 314 Gene3D G3DSA:3.10.25.10 207 314 8.6E-38 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HW35_16555 29f6dd8cd17ea625a5cb67da243c4711 314 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HW35_16555 29f6dd8cd17ea625a5cb67da243c4711 314 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 302 2.6E-117 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 HW35_16555 29f6dd8cd17ea625a5cb67da243c4711 314 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 305 37.047 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 HW35_16555 29f6dd8cd17ea625a5cb67da243c4711 314 Pfam PF00551 Formyl transferase 3 180 2.0E-41 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HW35_16555 29f6dd8cd17ea625a5cb67da243c4711 314 SUPERFAMILY SSF53328 3 206 8.77E-70 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HW35_16555 29f6dd8cd17ea625a5cb67da243c4711 314 SUPERFAMILY SSF50486 205 309 7.53E-32 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 HW35_16555 29f6dd8cd17ea625a5cb67da243c4711 314 Gene3D G3DSA:3.40.50.170 1 206 1.4E-87 T 12-10-2018 HW35_16555 29f6dd8cd17ea625a5cb67da243c4711 314 Pfam PF02911 Formyl transferase, C-terminal domain 204 302 1.1E-28 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HW35_01645 c6d31311ae1a7aedeac642cd153b0ea6 467 Pfam PF07995 Glucose / Sorbosone dehydrogenase 30 271 2.2E-11 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase HW35_01645 c6d31311ae1a7aedeac642cd153b0ea6 467 Gene3D G3DSA:2.120.10.30 3 395 1.2E-27 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like HW35_01645 c6d31311ae1a7aedeac642cd153b0ea6 467 SUPERFAMILY SSF50952 65 256 9.15E-11 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 HW35_00925 abc9bff028486131e58df128e1376cef 320 SUPERFAMILY SSF55326 11 132 1.5E-35 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HW35_00925 abc9bff028486131e58df128e1376cef 320 Pfam PF00586 AIR synthase related protein, N-terminal domain 21 128 3.7E-18 T 12-10-2018 IPR016188 PurM-like, N-terminal domain HW35_00925 abc9bff028486131e58df128e1376cef 320 Gene3D G3DSA:3.90.650.10 136 316 2.8E-55 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HW35_00925 abc9bff028486131e58df128e1376cef 320 PIRSF PIRSF036407 1 320 7.8E-114 T 12-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 HW35_00925 abc9bff028486131e58df128e1376cef 320 TIGRFAM TIGR00476 selD: selenide, water dikinase 9 285 3.5E-112 T 12-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 HW35_00925 abc9bff028486131e58df128e1376cef 320 Pfam PF02769 AIR synthase related protein, C-terminal domain 140 318 6.4E-30 T 12-10-2018 IPR010918 PurM-like, C-terminal domain HW35_00925 abc9bff028486131e58df128e1376cef 320 Hamap MF_00625 Selenide, water dikinase [selD]. 1 319 36.566 T 12-10-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 HW35_00925 abc9bff028486131e58df128e1376cef 320 SUPERFAMILY SSF56042 134 316 7.33E-46 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HW35_00925 abc9bff028486131e58df128e1376cef 320 Gene3D G3DSA:3.30.1330.10 6 134 2.0E-39 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HW35_03580 aaee06761bd0ddea7aa3c45398123382 245 Pfam PF00849 RNA pseudouridylate synthase 62 196 2.1E-25 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_03580 aaee06761bd0ddea7aa3c45398123382 245 Gene3D G3DSA:3.10.290.10 1 57 6.4E-24 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HW35_03580 aaee06761bd0ddea7aa3c45398123382 245 Pfam PF01479 S4 domain 2 48 1.3E-17 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_03580 aaee06761bd0ddea7aa3c45398123382 245 SUPERFAMILY SSF55174 2 67 2.16E-18 T 12-10-2018 HW35_03580 aaee06761bd0ddea7aa3c45398123382 245 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 1.5E-53 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 HW35_03580 aaee06761bd0ddea7aa3c45398123382 245 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 HW35_03580 aaee06761bd0ddea7aa3c45398123382 245 Gene3D G3DSA:3.30.70.1560 123 215 2.0E-59 T 12-10-2018 HW35_03580 aaee06761bd0ddea7aa3c45398123382 245 Gene3D G3DSA:3.30.70.580 64 223 2.0E-59 T 12-10-2018 HW35_03580 aaee06761bd0ddea7aa3c45398123382 245 SMART SM00363 2 59 1.5E-17 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_03580 aaee06761bd0ddea7aa3c45398123382 245 SUPERFAMILY SSF55120 46 235 4.32E-46 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_12850 5bc9e096f96c58839066a461c6c6319d 235 Pfam PF03473 MOSC domain 56 167 9.1E-22 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 HW35_12850 5bc9e096f96c58839066a461c6c6319d 235 Pfam PF03475 3-alpha domain 178 221 6.9E-10 T 12-10-2018 IPR005163 3-alpha domain HW35_12850 5bc9e096f96c58839066a461c6c6319d 235 SUPERFAMILY SSF50800 26 233 1.2E-68 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily HW35_12850 5bc9e096f96c58839066a461c6c6319d 235 Gene3D G3DSA:2.40.33.20 2 235 4.9E-77 T 12-10-2018 HW35_01885 30cf21ae4d5f4713dd29aee2baf7d99f 453 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 36 47 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_01885 30cf21ae4d5f4713dd29aee2baf7d99f 453 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_01885 30cf21ae4d5f4713dd29aee2baf7d99f 453 Pfam PF02754 Cysteine-rich domain 335 418 3.5E-13 T 12-10-2018 IPR004017 Cysteine-rich domain HW35_01885 30cf21ae4d5f4713dd29aee2baf7d99f 453 Pfam PF02754 Cysteine-rich domain 208 289 7.6E-14 T 12-10-2018 IPR004017 Cysteine-rich domain HW35_01885 30cf21ae4d5f4713dd29aee2baf7d99f 453 Pfam PF13183 4Fe-4S dicluster domain 35 101 6.8E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HW35_01885 30cf21ae4d5f4713dd29aee2baf7d99f 453 PIRSF PIRSF000139 17 447 5.8E-156 T 12-10-2018 HW35_01885 30cf21ae4d5f4713dd29aee2baf7d99f 453 SUPERFAMILY SSF46548 32 115 7.85E-18 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HW35_01885 30cf21ae4d5f4713dd29aee2baf7d99f 453 Gene3D G3DSA:1.10.1060.10 24 124 4.9E-10 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HW35_04580 7173bacf095f63fdc820c98096935fff 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 1.4E-28 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_04580 7173bacf095f63fdc820c98096935fff 86 SUPERFAMILY SSF46992 3 86 7.19E-29 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_04580 7173bacf095f63fdc820c98096935fff 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 68 1.0E-6 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_04580 7173bacf095f63fdc820c98096935fff 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.741 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_04580 7173bacf095f63fdc820c98096935fff 86 Pfam PF01649 Ribosomal protein S20 2 84 1.7E-28 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_04580 7173bacf095f63fdc820c98096935fff 86 Gene3D G3DSA:1.20.58.110 1 86 1.3E-29 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 SMART SM00358 174 241 1.8E-22 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 Gene3D G3DSA:3.30.160.20 173 239 5.6E-24 T 12-10-2018 HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 21 239 1.1E-81 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 SUPERFAMILY SSF54768 130 241 4.71E-26 T 12-10-2018 HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 Hamap MF_00104 Ribonuclease 3 [rnc]. 21 237 32.075 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 SUPERFAMILY SSF69065 13 175 4.19E-53 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 Pfam PF00035 Double-stranded RNA binding motif 175 240 1.9E-18 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 ProSitePatterns PS00517 Ribonuclease III family signature. 57 65 - T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 SMART SM00535 33 168 3.0E-59 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 Gene3D G3DSA:1.10.1520.10 17 165 6.4E-49 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 HW35_16655 a49420a73beac5dbbe6a94c2c72faa39 245 Pfam PF14622 Ribonuclease-III-like 31 162 3.8E-37 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 HW35_13555 52371aebcaa5a16e9b6c75b545686735 149 Pfam PF02830 V4R domain 87 146 1.8E-8 T 12-10-2018 IPR004096 4-vinyl reductase, 4VR HW35_13555 52371aebcaa5a16e9b6c75b545686735 149 SUPERFAMILY SSF111126 4 147 1.41E-23 T 12-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily HW35_13555 52371aebcaa5a16e9b6c75b545686735 149 SMART SM00989 86 148 4.6E-8 T 12-10-2018 IPR004096 4-vinyl reductase, 4VR HW35_13555 52371aebcaa5a16e9b6c75b545686735 149 Gene3D G3DSA:3.30.1380.20 4 148 6.4E-26 T 12-10-2018 HW35_11065 892b74f5de2aed5d8192cd7417afcc74 187 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 1 186 6.0E-100 T 12-10-2018 IPR014294 RNA polymerase sigma-W, bacillaceae HW35_11065 892b74f5de2aed5d8192cd7417afcc74 187 Gene3D G3DSA:1.10.10.10 121 186 4.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_11065 892b74f5de2aed5d8192cd7417afcc74 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 184 5.9E-37 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_11065 892b74f5de2aed5d8192cd7417afcc74 187 Gene3D G3DSA:1.10.1740.10 5 98 2.3E-31 T 12-10-2018 HW35_11065 892b74f5de2aed5d8192cd7417afcc74 187 Pfam PF04542 Sigma-70 region 2 24 89 1.6E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_11065 892b74f5de2aed5d8192cd7417afcc74 187 SUPERFAMILY SSF88659 117 184 7.48E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_11065 892b74f5de2aed5d8192cd7417afcc74 187 Pfam PF08281 Sigma-70, region 4 130 180 1.1E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_11065 892b74f5de2aed5d8192cd7417afcc74 187 SUPERFAMILY SSF88946 8 98 3.45E-30 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_12235 767b4aee8ff7b230191443fe3a8fd943 281 Pfam PF00005 ABC transporter 19 167 3.0E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12235 767b4aee8ff7b230191443fe3a8fd943 281 SUPERFAMILY SSF52540 4 230 2.72E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12235 767b4aee8ff7b230191443fe3a8fd943 281 Gene3D G3DSA:3.40.50.300 2 258 7.6E-69 T 12-10-2018 HW35_12235 767b4aee8ff7b230191443fe3a8fd943 281 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_12235 767b4aee8ff7b230191443fe3a8fd943 281 SMART SM00382 28 217 3.1E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 335 65.994 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 Gene3D G3DSA:3.30.420.40 132 297 6.7E-129 T 12-10-2018 HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 Gene3D G3DSA:3.30.420.40 7 319 6.7E-129 T 12-10-2018 HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 Pfam PF00814 Glycoprotease family 27 310 2.0E-108 T 12-10-2018 IPR000905 Gcp-like domain HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 SUPERFAMILY SSF53067 105 312 3.37E-45 T 12-10-2018 HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 SUPERFAMILY SSF53067 6 127 2.85E-33 T 12-10-2018 HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 12-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 1.9E-51 T 12-10-2018 IPR017861 Kae1/TsaD family HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 1.9E-51 T 12-10-2018 IPR017861 Kae1/TsaD family HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 1.9E-51 T 12-10-2018 IPR017861 Kae1/TsaD family HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 1.9E-51 T 12-10-2018 IPR017861 Kae1/TsaD family HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 1.9E-51 T 12-10-2018 IPR017861 Kae1/TsaD family HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 1.9E-51 T 12-10-2018 IPR017861 Kae1/TsaD family HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 317 3.3E-138 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 HW35_11550 5a32fc340119a8897ee4240809bc3fc2 340 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 310 7.6E-115 T 12-10-2018 IPR017861 Kae1/TsaD family HW35_04825 dd40b3f62ada79e05ed523232cd9f6cc 422 Gene3D G3DSA:1.10.8.60 150 225 2.5E-20 T 12-10-2018 HW35_04825 dd40b3f62ada79e05ed523232cd9f6cc 422 SMART SM00382 38 150 1.9E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_04825 dd40b3f62ada79e05ed523232cd9f6cc 422 Gene3D G3DSA:3.40.50.300 1 149 4.8E-41 T 12-10-2018 HW35_04825 dd40b3f62ada79e05ed523232cd9f6cc 422 Pfam PF12002 MgsA AAA+ ATPase C terminal 253 418 6.8E-66 T 12-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal HW35_04825 dd40b3f62ada79e05ed523232cd9f6cc 422 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 8 125 1.0E-16 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 HW35_04825 dd40b3f62ada79e05ed523232cd9f6cc 422 SUPERFAMILY SSF52540 3 219 2.3E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04825 dd40b3f62ada79e05ed523232cd9f6cc 422 Pfam PF16193 AAA C-terminal domain 174 252 2.6E-25 T 12-10-2018 IPR032423 AAA C-terminal domain HW35_04825 dd40b3f62ada79e05ed523232cd9f6cc 422 Gene3D G3DSA:1.10.3710.10 332 422 2.3E-24 T 12-10-2018 HW35_04825 dd40b3f62ada79e05ed523232cd9f6cc 422 SUPERFAMILY SSF48019 238 419 8.5E-72 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 HW35_04825 dd40b3f62ada79e05ed523232cd9f6cc 422 Gene3D G3DSA:1.20.272.10 227 331 7.5E-42 T 12-10-2018 HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 SMART SM00419 163 211 1.3E-16 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 Gene3D G3DSA:2.60.120.10 5 140 1.3E-27 T 12-10-2018 IPR014710 RmlC-like jelly roll fold HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 Pfam PF13545 Crp-like helix-turn-helix domain 146 217 4.5E-20 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 ProSitePatterns PS00042 Crp-type HTH domain signature. 171 194 - T 12-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 SUPERFAMILY SSF46785 142 225 8.51E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 Gene3D G3DSA:1.10.10.10 141 231 1.2E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 SMART SM00100 1 124 7.5E-15 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 185 200 1.2E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 169 185 1.2E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 Pfam PF00027 Cyclic nucleotide-binding domain 27 108 4.4E-16 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain HW35_15195 366b7574a8797399ff2c4e27f681cc11 232 SUPERFAMILY SSF51206 24 140 2.49E-26 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 SMART SM01016 5 95 1.2E-34 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 Gene3D G3DSA:3.40.50.620 124 431 1.3E-180 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 Gene3D G3DSA:3.30.1360.70 2 115 3.3E-28 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 Pfam PF05746 DALR anticodon binding domain 438 556 1.1E-39 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 8 556 1.1E-181 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 3.5E-25 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 3.5E-25 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 3.5E-25 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 3.5E-25 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 SUPERFAMILY SSF47323 432 556 1.31E-37 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 94 3.0E-25 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 SUPERFAMILY SSF52374 118 448 2.28E-101 T 12-10-2018 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 556 29.099 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 SUPERFAMILY SSF55190 1 115 2.75E-28 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 Pfam PF00750 tRNA synthetases class I (R) 104 401 2.3E-30 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 SMART SM00836 437 556 1.9E-56 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HW35_09310 5d38e65d0d1be1a82aa5386268ef6007 556 Gene3D G3DSA:1.10.730.10 432 556 1.3E-180 T 12-10-2018 HW35_10385 c8216d967bbc906e08c808a942c968cf 309 Gene3D G3DSA:3.40.50.1100 46 145 3.9E-123 T 12-10-2018 HW35_10385 c8216d967bbc906e08c808a942c968cf 309 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 304 1.0E-139 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 HW35_10385 c8216d967bbc906e08c808a942c968cf 309 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 HW35_10385 c8216d967bbc906e08c808a942c968cf 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 293 2.5E-71 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HW35_10385 c8216d967bbc906e08c808a942c968cf 309 SUPERFAMILY SSF53686 3 305 1.7E-105 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HW35_10385 c8216d967bbc906e08c808a942c968cf 309 Gene3D G3DSA:3.40.50.1100 7 300 3.9E-123 T 12-10-2018 HW35_10385 c8216d967bbc906e08c808a942c968cf 309 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 304 1.5E-132 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 HW35_15930 1de590b84b9f1366e3017a14e07c3d13 371 Gene3D G3DSA:3.40.50.970 6 371 6.6E-122 T 12-10-2018 HW35_15930 1de590b84b9f1366e3017a14e07c3d13 371 SUPERFAMILY SSF52518 13 367 2.4E-101 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_15930 1de590b84b9f1366e3017a14e07c3d13 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 25 364 1.5E-143 T 12-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 HW35_15930 1de590b84b9f1366e3017a14e07c3d13 371 Pfam PF00676 Dehydrogenase E1 component 53 343 9.0E-104 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 HW35_04510 085c3a73956aebbd36fcf957efe050ab 57 Gene3D G3DSA:1.20.5.1150 16 56 2.7E-18 T 12-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04510 085c3a73956aebbd36fcf957efe050ab 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 20.733 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04510 085c3a73956aebbd36fcf957efe050ab 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 8.0E-9 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04510 085c3a73956aebbd36fcf957efe050ab 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 12-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_04510 085c3a73956aebbd36fcf957efe050ab 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.7E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04510 085c3a73956aebbd36fcf957efe050ab 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.7E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04510 085c3a73956aebbd36fcf957efe050ab 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.7E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04510 085c3a73956aebbd36fcf957efe050ab 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.7E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04510 085c3a73956aebbd36fcf957efe050ab 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 57 1.6E-21 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04510 085c3a73956aebbd36fcf957efe050ab 57 Pfam PF01165 Ribosomal protein S21 5 57 1.4E-20 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_07085 4540c18345697bd87b8dd0d64b95c1ac 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 223 5.7E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_07085 4540c18345697bd87b8dd0d64b95c1ac 224 Gene3D G3DSA:1.10.3720.10 10 224 2.8E-49 T 12-10-2018 IPR035906 MetI-like superfamily HW35_07085 4540c18345697bd87b8dd0d64b95c1ac 224 SUPERFAMILY SSF161098 13 211 2.49E-46 T 12-10-2018 IPR035906 MetI-like superfamily HW35_17550 f04d1c4a7d3e76ddf1b6cd2767e0349d 1045 Gene3D G3DSA:3.40.50.300 2 203 4.8E-40 T 12-10-2018 HW35_17550 f04d1c4a7d3e76ddf1b6cd2767e0349d 1045 SUPERFAMILY SSF52540 25 1026 1.11E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17550 f04d1c4a7d3e76ddf1b6cd2767e0349d 1045 SUPERFAMILY SSF52540 3 502 4.09E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17550 f04d1c4a7d3e76ddf1b6cd2767e0349d 1045 Pfam PF13476 AAA domain 5 292 1.8E-8 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain HW35_17550 f04d1c4a7d3e76ddf1b6cd2767e0349d 1045 Pfam PF13558 Putative exonuclease SbcCD, C subunit 939 1001 3.0E-12 T 12-10-2018 HW35_17550 f04d1c4a7d3e76ddf1b6cd2767e0349d 1045 Gene3D G3DSA:3.40.50.300 735 1043 2.9E-28 T 12-10-2018 HW35_12170 5c77d33ea526f44e087c7f7fd82bcb37 227 Gene3D G3DSA:3.30.70.2970 37 143 7.7E-55 T 12-10-2018 HW35_12170 5c77d33ea526f44e087c7f7fd82bcb37 227 Gene3D G3DSA:3.30.110.170 27 223 7.7E-55 T 12-10-2018 HW35_12170 5c77d33ea526f44e087c7f7fd82bcb37 227 Pfam PF04402 Protein of unknown function (DUF541) 26 223 5.6E-43 T 12-10-2018 IPR007497 Protein of unknown function DUF541 HW35_07355 ac131cef3f4c613d7462eda28b0c1899 155 SUPERFAMILY SSF74982 4 132 3.14E-56 T 12-10-2018 IPR023620 Small protein B HW35_07355 ac131cef3f4c613d7462eda28b0c1899 155 Gene3D G3DSA:2.40.280.10 3 128 1.7E-54 T 12-10-2018 IPR023620 Small protein B HW35_07355 ac131cef3f4c613d7462eda28b0c1899 155 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site HW35_07355 ac131cef3f4c613d7462eda28b0c1899 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 79.789 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 HW35_07355 ac131cef3f4c613d7462eda28b0c1899 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 8 149 7.0E-62 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 HW35_07355 ac131cef3f4c613d7462eda28b0c1899 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 5.0E-54 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 HW35_07355 ac131cef3f4c613d7462eda28b0c1899 155 Pfam PF01668 SmpB protein 9 150 2.5E-65 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 HW35_05410 fd46351637bfb753972623dc626fd8ba 420 SUPERFAMILY SSF56672 23 346 2.73E-58 T 12-10-2018 HW35_05410 fd46351637bfb753972623dc626fd8ba 420 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 9.9E-131 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_05410 fd46351637bfb753972623dc626fd8ba 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05410 fd46351637bfb753972623dc626fd8ba 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05410 fd46351637bfb753972623dc626fd8ba 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05410 fd46351637bfb753972623dc626fd8ba 420 Pfam PF08388 Group II intron, maturase-specific domain 288 360 4.0E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_05410 fd46351637bfb753972623dc626fd8ba 420 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 4.3E-49 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_15740 5fb1124e87877841bc416b8a82edd155 564 SUPERFAMILY SSF55486 34 561 1.83E-123 T 12-10-2018 HW35_15740 5fb1124e87877841bc416b8a82edd155 564 Gene3D G3DSA:1.10.1370.30 1 564 1.9E-219 T 12-10-2018 HW35_15740 5fb1124e87877841bc416b8a82edd155 564 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 14 560 3.4E-230 T 12-10-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 285 2.8E-107 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 271 284 - T 12-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 285 35.565 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 Gene3D G3DSA:3.40.1380.10 61 204 5.8E-101 T 12-10-2018 HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 PRINTS PR00126 ATP synthase gamma subunit signature 263 284 1.8E-40 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 1.8E-40 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 PRINTS PR00126 ATP synthase gamma subunit signature 232 251 1.8E-40 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 1.8E-40 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 Gene3D G3DSA:1.10.287.80 6 281 5.8E-101 T 12-10-2018 HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 SUPERFAMILY SSF52943 2 285 8.24E-91 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09090 f64293e66f93ae4769f8075a8de5bc03 286 Pfam PF00231 ATP synthase 3 285 1.6E-96 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 149 164 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 41 61 1.5E-69 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 170 191 1.5E-69 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 61 80 1.5E-69 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 149 169 1.5E-69 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 194 219 1.5E-69 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 22 41 1.5E-69 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 24 220 5.4E-90 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 Pfam PF00813 FliP family 24 216 5.7E-84 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 142 154 1.5E-23 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 80 92 1.5E-23 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 20 29 1.5E-23 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 92 106 1.5E-23 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 120 132 1.5E-23 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 210 220 1.5E-23 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HW35_00510 064d37c7f1dd410a609fe09ec3c47690 220 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 197 209 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HW35_14515 ef6ee0535e1bf59a9adc1d602ad99ff0 240 PIRSF PIRSF003073 1 238 1.5E-62 T 12-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HW35_14515 ef6ee0535e1bf59a9adc1d602ad99ff0 240 SMART SM00382 90 224 6.5E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_14515 ef6ee0535e1bf59a9adc1d602ad99ff0 240 Gene3D G3DSA:3.40.50.300 64 237 2.0E-43 T 12-10-2018 HW35_14515 ef6ee0535e1bf59a9adc1d602ad99ff0 240 SUPERFAMILY SSF52540 86 231 5.19E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14515 ef6ee0535e1bf59a9adc1d602ad99ff0 240 Pfam PF01695 IstB-like ATP binding protein 47 222 5.6E-49 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HW35_00035 0f01c8f518f582ee7b30b5c57cdb8a14 231 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HW35_00035 0f01c8f518f582ee7b30b5c57cdb8a14 231 Pfam PF01066 CDP-alcohol phosphatidyltransferase 8 71 7.6E-16 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HW35_00035 0f01c8f518f582ee7b30b5c57cdb8a14 231 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 13 170 1.5E-41 T 12-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 HW35_00035 0f01c8f518f582ee7b30b5c57cdb8a14 231 Gene3D G3DSA:1.20.120.1760 2 174 1.1E-15 T 12-10-2018 HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 5 342 38.379 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 PIRSF PIRSF000148 5 347 8.9E-133 T 12-10-2018 HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 SMART SM00859 7 122 6.2E-42 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 Gene3D G3DSA:3.40.50.720 8 339 1.1E-143 T 12-10-2018 HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 343 2.1E-161 T 12-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 SUPERFAMILY SSF51735 6 158 4.45E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 Gene3D G3DSA:3.30.360.10 129 325 1.1E-143 T 12-10-2018 HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 119 6.5E-35 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 238 252 - T 12-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 SUPERFAMILY SSF55347 130 329 1.34E-75 T 12-10-2018 HW35_16890 5808b94cd2b76dc9c613496b05c8c2c9 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 140 328 6.7E-58 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HW35_16000 455153dec573e7f5d6361d22dc52587e 205 Hamap MF_01851 UPF0637 protein . 5 202 40.75 T 12-10-2018 IPR009403 Protein of unknown function UPF0637 HW35_16000 455153dec573e7f5d6361d22dc52587e 205 PIRSF PIRSF021332 1 205 7.5E-92 T 12-10-2018 IPR009403 Protein of unknown function UPF0637 HW35_16000 455153dec573e7f5d6361d22dc52587e 205 Gene3D G3DSA:3.30.930.20 2 205 6.2E-84 T 12-10-2018 HW35_16000 455153dec573e7f5d6361d22dc52587e 205 SUPERFAMILY SSF142913 4 204 1.15E-83 T 12-10-2018 HW35_16000 455153dec573e7f5d6361d22dc52587e 205 Pfam PF06335 Protein of unknown function (DUF1054) 6 200 1.7E-84 T 12-10-2018 IPR009403 Protein of unknown function UPF0637 HW35_14250 c2088f20acff064997699704f9fc86d2 249 Gene3D G3DSA:3.40.50.720 2 249 6.2E-80 T 12-10-2018 HW35_14250 c2088f20acff064997699704f9fc86d2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14250 c2088f20acff064997699704f9fc86d2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14250 c2088f20acff064997699704f9fc86d2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14250 c2088f20acff064997699704f9fc86d2 249 SUPERFAMILY SSF51735 3 247 2.16E-80 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_14250 c2088f20acff064997699704f9fc86d2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.4E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14250 c2088f20acff064997699704f9fc86d2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.4E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14250 c2088f20acff064997699704f9fc86d2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.4E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14250 c2088f20acff064997699704f9fc86d2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.4E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14250 c2088f20acff064997699704f9fc86d2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.4E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14250 c2088f20acff064997699704f9fc86d2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.4E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14250 c2088f20acff064997699704f9fc86d2 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 246 3.0E-68 T 12-10-2018 HW35_01115 35407ddde4ccb5720778a244a8a5581e 259 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 258 1.3E-43 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 HW35_01115 35407ddde4ccb5720778a244a8a5581e 259 PIRSF PIRSF006157 1 259 1.9E-88 T 12-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 HW35_01115 35407ddde4ccb5720778a244a8a5581e 259 SUPERFAMILY SSF53213 1 259 4.19E-86 T 12-10-2018 HW35_01115 35407ddde4ccb5720778a244a8a5581e 259 Gene3D G3DSA:3.40.830.10 1 259 5.3E-85 T 12-10-2018 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 Gene3D G3DSA:3.20.20.150 8 442 1.0E-192 T 12-10-2018 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 PRINTS PR00688 Xylose isomerase signature 160 179 3.9E-99 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 PRINTS PR00688 Xylose isomerase signature 337 348 3.9E-99 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 PRINTS PR00688 Xylose isomerase signature 233 257 3.9E-99 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 PRINTS PR00688 Xylose isomerase signature 275 302 3.9E-99 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 PRINTS PR00688 Xylose isomerase signature 304 315 3.9E-99 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 PRINTS PR00688 Xylose isomerase signature 137 157 3.9E-99 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 PRINTS PR00688 Xylose isomerase signature 211 230 3.9E-99 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 PRINTS PR00688 Xylose isomerase signature 184 205 3.9E-99 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 PRINTS PR00688 Xylose isomerase signature 96 118 3.9E-99 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 SUPERFAMILY SSF51658 9 441 1.01E-177 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 Hamap MF_00455 Xylose isomerase [xylA]. 16 439 56.4 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 9 439 7.9E-223 T 12-10-2018 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HW35_11595 660748dc2d0eb9362e908b4b6936dd34 442 Pfam PF01261 Xylose isomerase-like TIM barrel 148 288 4.9E-7 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HW35_16845 159c87b21657d2edf17d36a0712172f1 304 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 216 8.1E-84 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_16845 159c87b21657d2edf17d36a0712172f1 304 Gene3D G3DSA:3.30.2350.10 1 242 2.8E-92 T 12-10-2018 HW35_16845 159c87b21657d2edf17d36a0712172f1 304 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 178 1.0E-59 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 HW35_16845 159c87b21657d2edf17d36a0712172f1 304 SUPERFAMILY SSF55120 1 237 2.36E-82 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_16845 159c87b21657d2edf17d36a0712172f1 304 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 301 19.753 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_16845 159c87b21657d2edf17d36a0712172f1 304 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 237 4.0E-14 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 HW35_15165 4f4f1d5713d556fd23c3861a0535bb77 61 Pfam PF12758 Protein of unknown function (DUF3813) 1 60 5.5E-25 T 12-10-2018 IPR024217 Protein of unknown function DUF3813 HW35_02935 331026840c7dc7813d213747dca723fe 281 Pfam PF00665 Integrase core domain 121 233 5.6E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_02935 331026840c7dc7813d213747dca723fe 281 SUPERFAMILY SSF53098 119 271 2.53E-24 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_02935 331026840c7dc7813d213747dca723fe 281 Gene3D G3DSA:3.30.420.10 92 273 2.6E-6 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_02935 331026840c7dc7813d213747dca723fe 281 Pfam PF13276 HTH-like domain 38 90 6.1E-10 T 12-10-2018 IPR025948 HTH-like domain HW35_03140 9efe8addc88abb0512df1b2a1eadcb66 123 Gene3D G3DSA:1.20.120.440 1 123 4.2E-37 T 12-10-2018 IPR023351 YppE-like superfamily HW35_03140 9efe8addc88abb0512df1b2a1eadcb66 123 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 9 115 4.1E-29 T 12-10-2018 IPR014913 Protein of unknown function DUF1798 HW35_03140 9efe8addc88abb0512df1b2a1eadcb66 123 SUPERFAMILY SSF140415 4 118 4.05E-31 T 12-10-2018 IPR023351 YppE-like superfamily HW35_14290 d8ea75c77fa0b7e5f68e01bdcc49ffcd 337 Pfam PF00005 ABC transporter 41 184 7.9E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_14290 d8ea75c77fa0b7e5f68e01bdcc49ffcd 337 SUPERFAMILY SSF52540 35 249 6.28E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14290 d8ea75c77fa0b7e5f68e01bdcc49ffcd 337 Gene3D G3DSA:3.40.50.300 2 293 4.8E-61 T 12-10-2018 HW35_14290 d8ea75c77fa0b7e5f68e01bdcc49ffcd 337 SMART SM00382 49 233 1.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 Gene3D G3DSA:1.25.10.110 294 370 5.0E-11 T 12-10-2018 HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 SUPERFAMILY SSF54862 164 251 2.18E-15 T 12-10-2018 HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 10 342 6.7E-129 T 12-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 SUPERFAMILY SSF48371 269 372 8.06E-10 T 12-10-2018 IPR016024 Armadillo-type fold HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 SMART SM00567 E-Z type HEAT repeats 330 359 1.4E-4 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 SMART SM00567 E-Z type HEAT repeats 298 327 3.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 Pfam PF13484 4Fe-4S double cluster binding domain 187 250 3.2E-17 T 12-10-2018 HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 43.432 T 12-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 Pfam PF13646 HEAT repeats 300 369 1.2E-8 T 12-10-2018 HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 Gene3D G3DSA:3.30.70.20 181 262 1.2E-5 T 12-10-2018 HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_14560 2afaa3ad27cd58af9a2c5a964026bbd5 381 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 2.7E-17 T 12-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 HW35_04910 c2ed0ce7051b86f328f5ebba4b962cb0 783 Pfam PF01368 DHH family 82 224 2.3E-9 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HW35_04910 c2ed0ce7051b86f328f5ebba4b962cb0 783 Gene3D G3DSA:3.10.310.30 318 443 1.7E-34 T 12-10-2018 HW35_04910 c2ed0ce7051b86f328f5ebba4b962cb0 783 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 567 769 1.9E-64 T 12-10-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal HW35_04910 c2ed0ce7051b86f328f5ebba4b962cb0 783 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 561 7.1E-178 T 12-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 HW35_04910 c2ed0ce7051b86f328f5ebba4b962cb0 783 SUPERFAMILY SSF64182 56 452 2.35E-123 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily HW35_04910 c2ed0ce7051b86f328f5ebba4b962cb0 783 Pfam PF02272 DHHA1 domain 314 437 8.0E-21 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HW35_04910 c2ed0ce7051b86f328f5ebba4b962cb0 783 Gene3D G3DSA:3.90.1640.30 56 317 7.9E-95 T 12-10-2018 HW35_17525 4b0d6f10851c10e336eb82463b62a847 480 ProSitePatterns PS00218 Amino acid permeases signature. 45 76 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 HW35_17525 4b0d6f10851c10e336eb82463b62a847 480 Pfam PF00324 Amino acid permease 20 462 1.4E-129 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 HW35_17525 4b0d6f10851c10e336eb82463b62a847 480 Gene3D G3DSA:1.20.1740.10 11 475 2.1E-70 T 12-10-2018 HW35_17525 4b0d6f10851c10e336eb82463b62a847 480 PIRSF PIRSF006060 1 476 6.7E-89 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HW35_15800 1242c01acd7c1d1f43f4b271236cd8e3 292 PIRSF PIRSF000103 3 292 4.8E-72 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 HW35_15800 1242c01acd7c1d1f43f4b271236cd8e3 292 Gene3D G3DSA:1.10.1040.10 168 292 2.5E-40 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HW35_15800 1242c01acd7c1d1f43f4b271236cd8e3 292 Gene3D G3DSA:3.40.50.720 3 167 8.7E-54 T 12-10-2018 HW35_15800 1242c01acd7c1d1f43f4b271236cd8e3 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 165 2.2E-50 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 HW35_15800 1242c01acd7c1d1f43f4b271236cd8e3 292 SUPERFAMILY SSF48179 169 291 7.03E-40 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_15800 1242c01acd7c1d1f43f4b271236cd8e3 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 170 289 5.4E-36 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 HW35_15800 1242c01acd7c1d1f43f4b271236cd8e3 292 SUPERFAMILY SSF51735 9 168 1.15E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_13895 495c686f0fade5627a036837d9ab751e 182 SUPERFAMILY SSF55729 1 172 1.3E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_13895 495c686f0fade5627a036837d9ab751e 182 Pfam PF00583 Acetyltransferase (GNAT) family 59 136 3.6E-12 T 12-10-2018 IPR000182 GNAT domain HW35_13895 495c686f0fade5627a036837d9ab751e 182 Gene3D G3DSA:3.40.630.30 2 161 4.9E-20 T 12-10-2018 HW35_01675 5823a89658e51c982c0c686e0a8a4c5d 558 Gene3D G3DSA:3.40.50.10730 139 346 1.4E-256 T 12-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_01675 5823a89658e51c982c0c686e0a8a4c5d 558 TIGRFAM TIGR01228 hutU: urocanate hydratase 9 551 0.0 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_01675 5823a89658e51c982c0c686e0a8a4c5d 558 Pfam PF17392 Urocanase C-terminal domain 349 543 2.5E-94 T 12-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_01675 5823a89658e51c982c0c686e0a8a4c5d 558 PIRSF PIRSF001423 1 557 5.0E-299 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_01675 5823a89658e51c982c0c686e0a8a4c5d 558 Pfam PF17391 Urocanase N-terminal domain 9 135 2.0E-61 T 12-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_01675 5823a89658e51c982c0c686e0a8a4c5d 558 Gene3D G3DSA:3.40.1770.10 17 539 1.4E-256 T 12-10-2018 HW35_01675 5823a89658e51c982c0c686e0a8a4c5d 558 Pfam PF01175 Urocanase Rossmann-like domain 138 346 3.0E-90 T 12-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_01675 5823a89658e51c982c0c686e0a8a4c5d 558 Hamap MF_00577 Urocanate hydratase [hutU]. 1 553 50.856 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_01675 5823a89658e51c982c0c686e0a8a4c5d 558 SUPERFAMILY SSF111326 4 553 1.02E-261 T 12-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_01675 5823a89658e51c982c0c686e0a8a4c5d 558 ProSitePatterns PS01233 Urocanase signature. 439 454 - T 12-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_00865 32ad76e535f3f726f52aa957a543a158 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 27.686 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 HW35_00865 32ad76e535f3f726f52aa957a543a158 211 SUPERFAMILY SSF52218 2 210 8.87E-54 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_00865 32ad76e535f3f726f52aa957a543a158 211 Gene3D G3DSA:3.40.50.360 1 211 1.6E-61 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_00865 32ad76e535f3f726f52aa957a543a158 211 Pfam PF02525 Flavodoxin-like fold 2 206 5.5E-48 T 12-10-2018 IPR003680 Flavodoxin-like fold HW35_00560 4b7d4acb78a30fc292f31f8c3b90f341 188 SUPERFAMILY SSF48150 1 183 2.46E-85 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 HW35_00560 4b7d4acb78a30fc292f31f8c3b90f341 188 Pfam PF03352 Methyladenine glycosylase 6 182 1.4E-86 T 12-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 HW35_00560 4b7d4acb78a30fc292f31f8c3b90f341 188 Gene3D G3DSA:1.10.340.30 1 186 3.1E-89 T 12-10-2018 HW35_00560 4b7d4acb78a30fc292f31f8c3b90f341 188 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 3 180 7.0E-77 T 12-10-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 HW35_10100 7b24bf7fbe4152a952340898a969dd8a 198 Pfam PF02132 RecR protein 40 78 6.4E-17 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger HW35_10100 7b24bf7fbe4152a952340898a969dd8a 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 12-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 HW35_10100 7b24bf7fbe4152a952340898a969dd8a 198 SMART SM00493 80 165 5.9E-19 T 12-10-2018 IPR006171 TOPRIM domain HW35_10100 7b24bf7fbe4152a952340898a969dd8a 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 4.0E-91 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 HW35_10100 7b24bf7fbe4152a952340898a969dd8a 198 SUPERFAMILY SSF111304 1 198 2.48E-79 T 12-10-2018 IPR023627 Recombination protein RecR HW35_10100 7b24bf7fbe4152a952340898a969dd8a 198 Gene3D G3DSA:1.10.8.420 1 53 7.4E-21 T 12-10-2018 HW35_10100 7b24bf7fbe4152a952340898a969dd8a 198 Gene3D G3DSA:3.40.1360.10 77 198 1.0E-49 T 12-10-2018 HW35_10100 7b24bf7fbe4152a952340898a969dd8a 198 Pfam PF13662 Toprim domain 80 171 6.2E-26 T 12-10-2018 IPR006171 TOPRIM domain HW35_10100 7b24bf7fbe4152a952340898a969dd8a 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 112.331 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 HW35_04795 b3d62d6fb2a35bef4c57304e0487fbc6 158 SUPERFAMILY SSF50346 3 68 1.44E-6 T 12-10-2018 IPR011033 PRC-barrel-like superfamily HW35_04795 b3d62d6fb2a35bef4c57304e0487fbc6 158 SUPERFAMILY SSF50346 90 154 1.36E-5 T 12-10-2018 IPR011033 PRC-barrel-like superfamily HW35_04795 b3d62d6fb2a35bef4c57304e0487fbc6 158 Pfam PF05239 PRC-barrel domain 5 67 1.1E-7 T 12-10-2018 IPR027275 PRC-barrel domain HW35_04795 b3d62d6fb2a35bef4c57304e0487fbc6 158 Pfam PF05239 PRC-barrel domain 89 155 6.9E-7 T 12-10-2018 IPR027275 PRC-barrel domain HW35_04795 b3d62d6fb2a35bef4c57304e0487fbc6 158 Gene3D G3DSA:2.30.30.240 1 70 2.1E-5 T 12-10-2018 HW35_14220 6ada3dbf876cacc0f1698176411631a0 112 SUPERFAMILY SSF101697 6 109 6.02E-47 T 12-10-2018 IPR036289 Hypothetical protein YfhH HW35_14220 6ada3dbf876cacc0f1698176411631a0 112 Pfam PF08838 Protein of unknown function (DUF1811) 10 109 1.1E-45 T 12-10-2018 IPR014938 Protein of unknown function DUF1811 HW35_14220 6ada3dbf876cacc0f1698176411631a0 112 Gene3D G3DSA:2.30.30.340 58 111 4.4E-28 T 12-10-2018 HW35_14220 6ada3dbf876cacc0f1698176411631a0 112 Gene3D G3DSA:1.10.287.880 4 57 2.9E-25 T 12-10-2018 HW35_09050 8af4bc581f9a4dcaf8fdb589f312fd65 139 Gene3D G3DSA:3.30.70.3270 24 139 7.6E-32 T 12-10-2018 HW35_09050 8af4bc581f9a4dcaf8fdb589f312fd65 139 Pfam PF12838 4Fe-4S dicluster domain 45 102 4.2E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HW35_09050 8af4bc581f9a4dcaf8fdb589f312fd65 139 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_09050 8af4bc581f9a4dcaf8fdb589f312fd65 139 SUPERFAMILY SSF54862 24 117 3.18E-23 T 12-10-2018 HW35_07695 6cfe369e691d5a52c4f364f3566f25b6 314 Gene3D G3DSA:3.40.1390.20 3 130 4.4E-45 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily HW35_07695 6cfe369e691d5a52c4f364f3566f25b6 314 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 301 3.0E-122 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 HW35_07695 6cfe369e691d5a52c4f364f3566f25b6 314 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 2.2E-79 T 12-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 HW35_07695 6cfe369e691d5a52c4f364f3566f25b6 314 Gene3D G3DSA:3.40.50.300 131 313 2.5E-77 T 12-10-2018 HW35_07695 6cfe369e691d5a52c4f364f3566f25b6 314 Pfam PF02603 HPr Serine kinase N terminus 4 127 3.4E-42 T 12-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 HW35_07695 6cfe369e691d5a52c4f364f3566f25b6 314 SUPERFAMILY SSF53795 132 298 3.97E-43 T 12-10-2018 HW35_07695 6cfe369e691d5a52c4f364f3566f25b6 314 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 42.902 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 HW35_07695 6cfe369e691d5a52c4f364f3566f25b6 314 SUPERFAMILY SSF75138 3 131 1.7E-41 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily HW35_01190 f3381b29153ab99bdbde9088a1d320ec 297 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_01190 f3381b29153ab99bdbde9088a1d320ec 297 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_01190 f3381b29153ab99bdbde9088a1d320ec 297 Gene3D G3DSA:1.10.357.10 1 168 3.3E-26 T 12-10-2018 HW35_01190 f3381b29153ab99bdbde9088a1d320ec 297 SUPERFAMILY SSF46689 3 62 1.4E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_01190 f3381b29153ab99bdbde9088a1d320ec 297 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 53 2.0E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_01190 f3381b29153ab99bdbde9088a1d320ec 297 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HW35_09955 13e7754e6a2203c6dc9c481cb7e2fb50 257 Pfam PF02096 60Kd inner membrane protein 58 240 5.0E-62 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HW35_09955 13e7754e6a2203c6dc9c481cb7e2fb50 257 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 245 32.4 T 12-10-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 HW35_09955 13e7754e6a2203c6dc9c481cb7e2fb50 257 PRINTS PR01900 YidC translocation/secretion protein signature 174 189 2.5E-7 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HW35_09955 13e7754e6a2203c6dc9c481cb7e2fb50 257 PRINTS PR01900 YidC translocation/secretion protein signature 196 220 2.5E-7 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HW35_09955 13e7754e6a2203c6dc9c481cb7e2fb50 257 PRINTS PR00701 60kDa inner membrane protein signature 207 230 5.2E-15 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HW35_09955 13e7754e6a2203c6dc9c481cb7e2fb50 257 PRINTS PR00701 60kDa inner membrane protein signature 123 146 5.2E-15 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HW35_09955 13e7754e6a2203c6dc9c481cb7e2fb50 257 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 57 240 3.4E-67 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_17670 3f9b887f5a87432ce2b700373ec2c030 392 Pfam PF07687 Peptidase dimerisation domain 185 273 3.9E-8 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain HW35_17670 3f9b887f5a87432ce2b700373ec2c030 392 PIRSF PIRSF005962 2 389 7.9E-135 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 HW35_17670 3f9b887f5a87432ce2b700373ec2c030 392 SUPERFAMILY SSF53187 6 385 3.55E-85 T 12-10-2018 HW35_17670 3f9b887f5a87432ce2b700373ec2c030 392 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 13 373 3.4E-119 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 HW35_17670 3f9b887f5a87432ce2b700373ec2c030 392 Gene3D G3DSA:3.30.70.360 180 294 5.7E-147 T 12-10-2018 HW35_17670 3f9b887f5a87432ce2b700373ec2c030 392 SUPERFAMILY SSF55031 182 295 1.7E-27 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain HW35_17670 3f9b887f5a87432ce2b700373ec2c030 392 Gene3D G3DSA:3.40.630.10 13 370 5.7E-147 T 12-10-2018 HW35_17670 3f9b887f5a87432ce2b700373ec2c030 392 Pfam PF01546 Peptidase family M20/M25/M40 71 381 8.8E-36 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 HW35_16700 68faa912d518e4b6cfaa28b4c22704f9 247 PIRSF PIRSF000386 2 247 9.9E-107 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HW35_16700 68faa912d518e4b6cfaa28b4c22704f9 247 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 24 223 1.1E-73 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HW35_16700 68faa912d518e4b6cfaa28b4c22704f9 247 Gene3D G3DSA:1.10.1270.20 168 247 2.7E-35 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HW35_16700 68faa912d518e4b6cfaa28b4c22704f9 247 SUPERFAMILY SSF75217 2 246 1.05E-102 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases HW35_16700 68faa912d518e4b6cfaa28b4c22704f9 247 Gene3D G3DSA:3.40.1280.10 1 167 8.6E-70 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HW35_16700 68faa912d518e4b6cfaa28b4c22704f9 247 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 2 237 9.0E-104 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HW35_16700 68faa912d518e4b6cfaa28b4c22704f9 247 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 247 115.701 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HW35_03280 87b32421312d9d21c0ad2c0c215fc3f3 257 PIRSF PIRSF036636 1 257 3.2E-141 T 12-10-2018 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 HW35_03280 87b32421312d9d21c0ad2c0c215fc3f3 257 SUPERFAMILY SSF46626 143 254 1.58E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HW35_03280 87b32421312d9d21c0ad2c0c215fc3f3 257 SUPERFAMILY SSF81648 28 162 7.06E-30 T 12-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 HW35_03280 87b32421312d9d21c0ad2c0c215fc3f3 257 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 187 251 5.8E-13 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_03280 87b32421312d9d21c0ad2c0c215fc3f3 257 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 73 160 5.3E-9 T 12-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 HW35_03280 87b32421312d9d21c0ad2c0c215fc3f3 257 Gene3D G3DSA:1.20.810.10 14 176 1.6E-25 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 HW35_03280 87b32421312d9d21c0ad2c0c215fc3f3 257 Gene3D G3DSA:1.10.760.10 185 253 4.6E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HW35_15240 17760d30aa23baf6cce7c8a9152e3868 278 SUPERFAMILY SSF51735 3 224 2.01E-6 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_15240 17760d30aa23baf6cce7c8a9152e3868 278 Gene3D G3DSA:3.40.50.720 134 274 1.4E-6 T 12-10-2018 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 SUPERFAMILY SSF82866 799 1020 1.44E-44 T 12-10-2018 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 Gene3D G3DSA:3.30.2090.10 177 272 2.1E-266 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 3.9E-46 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 3.9E-46 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 3.9E-46 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 3.9E-46 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 3.9E-46 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 3.9E-46 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 3.9E-46 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 Gene3D G3DSA:3.30.70.1430 41 806 2.1E-266 T 12-10-2018 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 SUPERFAMILY SSF82693 133 313 2.44E-15 T 12-10-2018 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 SUPERFAMILY SSF82714 711 796 1.16E-7 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 Gene3D G3DSA:3.30.70.1430 559 656 2.1E-266 T 12-10-2018 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 SUPERFAMILY SSF82866 293 494 3.66E-44 T 12-10-2018 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 Gene3D G3DSA:1.20.1640.10 507 1012 2.1E-266 T 12-10-2018 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 SUPERFAMILY SSF82714 182 266 9.02E-7 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 Gene3D G3DSA:3.30.70.1320 131 327 2.1E-266 T 12-10-2018 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 Gene3D G3DSA:3.30.2090.10 708 798 2.1E-266 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 SUPERFAMILY SSF82693 41 132 2.09E-19 T 12-10-2018 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 Pfam PF00873 AcrB/AcrD/AcrF family 5 1015 2.3E-198 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 Gene3D G3DSA:1.20.1640.10 11 506 2.1E-266 T 12-10-2018 HW35_01775 817c57b06f053e16541934c5bdbde4b2 1029 Gene3D G3DSA:3.30.70.1440 657 855 2.1E-266 T 12-10-2018 HW35_06795 abd228aa0f60a601de6853d75307794a 449 Gene3D G3DSA:3.40.50.10490 1 62 4.8E-20 T 12-10-2018 HW35_06795 abd228aa0f60a601de6853d75307794a 449 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_06795 abd228aa0f60a601de6853d75307794a 449 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 26.855 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_06795 abd228aa0f60a601de6853d75307794a 449 Gene3D G3DSA:3.40.50.10490 63 226 4.4E-150 T 12-10-2018 HW35_06795 abd228aa0f60a601de6853d75307794a 449 Pfam PF00342 Phosphoglucose isomerase 76 296 1.7E-18 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_06795 abd228aa0f60a601de6853d75307794a 449 Gene3D G3DSA:3.40.50.10490 227 417 4.4E-150 T 12-10-2018 HW35_06795 abd228aa0f60a601de6853d75307794a 449 SUPERFAMILY SSF53697 5 447 4.58E-146 T 12-10-2018 HW35_06795 abd228aa0f60a601de6853d75307794a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 8.5E-28 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_06795 abd228aa0f60a601de6853d75307794a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 8.5E-28 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_06795 abd228aa0f60a601de6853d75307794a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 8.5E-28 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_06795 abd228aa0f60a601de6853d75307794a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 8.5E-28 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_06795 abd228aa0f60a601de6853d75307794a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 8.5E-28 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_06795 abd228aa0f60a601de6853d75307794a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 8.5E-28 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_06795 abd228aa0f60a601de6853d75307794a 449 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_03290 ffe23e58f02987fe3632f5815314d160 168 Pfam PF08802 Cytochrome B6-F complex Fe-S subunit 7 36 2.9E-5 T 12-10-2018 IPR014909 Cytochrome b6-f complex Fe-S subunit GO:0009496|GO:0042651|GO:0051537|GO:0055114 KEGG: 00195+1.10.9.1|MetaCyc: PWY-101 HW35_03290 ffe23e58f02987fe3632f5815314d160 168 Pfam PF00355 Rieske [2Fe-2S] domain 81 149 6.1E-14 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 HW35_03290 ffe23e58f02987fe3632f5815314d160 168 Gene3D G3DSA:2.102.10.10 46 167 8.5E-23 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 HW35_03290 ffe23e58f02987fe3632f5815314d160 168 SUPERFAMILY SSF50022 5 159 2.36E-29 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 HW35_00425 4089582ee03837bd30b43182b6bad2c8 300 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 4 187 2.5E-59 T 12-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 HW35_00425 4089582ee03837bd30b43182b6bad2c8 300 Gene3D G3DSA:1.20.1330.10 42 245 8.4E-59 T 12-10-2018 HW35_00425 4089582ee03837bd30b43182b6bad2c8 300 SUPERFAMILY SSF64518 1 300 1.83E-74 T 12-10-2018 HW35_00425 4089582ee03837bd30b43182b6bad2c8 300 Pfam PF00669 Bacterial flagellin N-terminal helical region 7 140 2.9E-31 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HW35_13350 6bfcbd7a648d412f6483e7d7dcb45a86 917 Gene3D G3DSA:3.40.50.300 380 603 4.5E-30 T 12-10-2018 HW35_13350 6bfcbd7a648d412f6483e7d7dcb45a86 917 SUPERFAMILY SSF52540 376 571 7.09E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13350 6bfcbd7a648d412f6483e7d7dcb45a86 917 SUPERFAMILY SSF48452 35 168 1.83E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_13350 6bfcbd7a648d412f6483e7d7dcb45a86 917 Gene3D G3DSA:1.25.40.10 11 193 2.3E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_13350 6bfcbd7a648d412f6483e7d7dcb45a86 917 Pfam PF00350 Dynamin family 381 518 1.5E-14 T 12-10-2018 IPR022812 Dynamin superfamily HW35_11140 0ca45561baa748e88b9196c7301d15db 206 Pfam PF07563 Protein of unknown function (DUF1541) 86 137 7.1E-27 T 12-10-2018 IPR011438 Domain of unknown function DUF1541 HW35_11140 0ca45561baa748e88b9196c7301d15db 206 Pfam PF07563 Protein of unknown function (DUF1541) 150 200 4.5E-25 T 12-10-2018 IPR011438 Domain of unknown function DUF1541 HW35_11140 0ca45561baa748e88b9196c7301d15db 206 Gene3D G3DSA:2.30.30.1210 61 205 1.5E-67 T 12-10-2018 HW35_05050 67bd47af38b8b4f104f35f44fb1fe863 102 SUPERFAMILY SSF141091 1 101 7.32E-40 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05050 67bd47af38b8b4f104f35f44fb1fe863 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 27.665 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05050 67bd47af38b8b4f104f35f44fb1fe863 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_05050 67bd47af38b8b4f104f35f44fb1fe863 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.6E-41 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05050 67bd47af38b8b4f104f35f44fb1fe863 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.5E-40 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05350 35bcf938319bd67016ea0880d68649e7 203 Hamap MF_01405 dITP/XTP pyrophosphatase. 2 195 49.146 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 HW35_05350 35bcf938319bd67016ea0880d68649e7 203 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 192 5.1E-67 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 HW35_05350 35bcf938319bd67016ea0880d68649e7 203 Gene3D G3DSA:3.90.950.10 1 197 1.6E-76 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HW35_05350 35bcf938319bd67016ea0880d68649e7 203 SUPERFAMILY SSF52972 1 193 1.54E-70 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HW35_05350 35bcf938319bd67016ea0880d68649e7 203 Pfam PF01725 Ham1 family 4 189 2.7E-59 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 SMART SM00926 2 57 4.7E-17 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 Gene3D G3DSA:3.40.228.10 133 524 3.5E-135 T 12-10-2018 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 404 421 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 Gene3D G3DSA:3.40.50.740 69 465 3.5E-135 T 12-10-2018 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 56 5.0E-16 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 SUPERFAMILY SSF50692 551 667 7.01E-25 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 SUPERFAMILY SSF53706 5 530 9.55E-149 T 12-10-2018 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 Pfam PF01568 Molydopterin dinucleotide binding domain 559 650 5.9E-12 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 Gene3D G3DSA:2.40.40.20 539 668 5.0E-22 T 12-10-2018 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 Gene3D G3DSA:3.30.2070.10 419 504 3.5E-135 T 12-10-2018 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 Gene3D G3DSA:2.20.25.90 3 61 1.6E-12 T 12-10-2018 HW35_09895 748521ade6c239ad73ac5bdd8a7b016f 668 Pfam PF00384 Molybdopterin oxidoreductase 60 460 4.5E-59 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_10725 fde9cd386cd3e8a45155bf1bbaffce80 95 SUPERFAMILY SSF54189 2 93 5.4E-32 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10725 fde9cd386cd3e8a45155bf1bbaffce80 95 Gene3D G3DSA:3.30.70.330 1 95 1.4E-32 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily HW35_10725 fde9cd386cd3e8a45155bf1bbaffce80 95 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 21.57 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 HW35_10725 fde9cd386cd3e8a45155bf1bbaffce80 95 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 12-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10725 fde9cd386cd3e8a45155bf1bbaffce80 95 Pfam PF00276 Ribosomal protein L23 6 88 8.0E-33 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 HW35_04625 080a305441812d98da80ad770153376a 251 Gene3D G3DSA:3.40.50.150 6 248 3.7E-82 T 12-10-2018 HW35_04625 080a305441812d98da80ad770153376a 251 SUPERFAMILY SSF53335 4 250 7.17E-52 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_04625 080a305441812d98da80ad770153376a 251 Pfam PF13649 Methyltransferase domain 44 138 6.4E-19 T 12-10-2018 HW35_04625 080a305441812d98da80ad770153376a 251 Gene3D G3DSA:2.20.25.110 146 209 3.7E-82 T 12-10-2018 HW35_08840 3732ad3c2173b64869c2e83cbc272391 249 Pfam PF13807 G-rich domain on putative tyrosine kinase 142 194 4.2E-9 T 12-10-2018 IPR032807 Tyrosine kinase, G-rich domain HW35_08840 3732ad3c2173b64869c2e83cbc272391 249 Pfam PF02706 Chain length determinant protein 3 94 2.1E-21 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 HW35_07200 7286bef9fdd8d60c03efbf8149f84e95 390 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 339 363 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_07200 7286bef9fdd8d60c03efbf8149f84e95 390 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 12 380 4.7E-106 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_07200 7286bef9fdd8d60c03efbf8149f84e95 390 Pfam PF01098 Cell cycle protein 15 381 5.0E-98 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_12570 387a83b80985f88182a207c2f87dd373 965 SMART SM00487 226 403 8.6E-9 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_12570 387a83b80985f88182a207c2f87dd373 965 Gene3D G3DSA:3.40.50.300 209 391 2.8E-46 T 12-10-2018 HW35_12570 387a83b80985f88182a207c2f87dd373 965 Pfam PF04851 Type III restriction enzyme, res subunit 225 376 8.4E-33 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HW35_12570 387a83b80985f88182a207c2f87dd373 965 SUPERFAMILY SSF56024 37 183 1.92E-15 T 12-10-2018 HW35_12570 387a83b80985f88182a207c2f87dd373 965 SMART SM00490 468 549 1.3E-13 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_12570 387a83b80985f88182a207c2f87dd373 965 Pfam PF13091 PLD-like domain 57 177 2.1E-15 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 HW35_12570 387a83b80985f88182a207c2f87dd373 965 Pfam PF11907 Domain of unknown function (DUF3427) 688 960 1.4E-84 T 12-10-2018 IPR021835 Protein of unknown function DUF3427 HW35_12570 387a83b80985f88182a207c2f87dd373 965 Gene3D G3DSA:3.30.870.10 37 200 2.2E-35 T 12-10-2018 HW35_12570 387a83b80985f88182a207c2f87dd373 965 Pfam PF00271 Helicase conserved C-terminal domain 450 547 4.0E-15 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_12570 387a83b80985f88182a207c2f87dd373 965 SUPERFAMILY SSF52540 272 570 1.47E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12570 387a83b80985f88182a207c2f87dd373 965 Gene3D G3DSA:3.40.50.300 419 602 7.1E-40 T 12-10-2018 HW35_12635 5f5790c1c46c77d90e619802d28bca5c 244 Gene3D G3DSA:3.40.33.10 10 242 1.1E-70 T 12-10-2018 IPR035940 CAP superfamily HW35_12635 5f5790c1c46c77d90e619802d28bca5c 244 Pfam PF00188 Cysteine-rich secretory protein family 129 240 3.5E-24 T 12-10-2018 IPR014044 CAP domain HW35_12635 5f5790c1c46c77d90e619802d28bca5c 244 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 121 243 5.3E-61 T 12-10-2018 IPR014258 CAP domain, YkwD-like HW35_12635 5f5790c1c46c77d90e619802d28bca5c 244 SUPERFAMILY SSF55797 121 239 2.49E-28 T 12-10-2018 IPR035940 CAP superfamily HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 SUPERFAMILY SSF52540 367 606 1.43E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 SUPERFAMILY SSF46689 582 684 6.27E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 582 591 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 Gene3D G3DSA:3.30.450.20 124 222 3.7E-18 T 12-10-2018 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 648 665 5.3E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 665 685 5.3E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 392 405 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 Gene3D G3DSA:3.40.50.300 354 539 1.6E-63 T 12-10-2018 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 234 349 2.5E-18 T 12-10-2018 IPR000014 PAS domain HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 121 227 5.6E-11 T 12-10-2018 IPR000014 PAS domain HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 455 470 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 SMART SM00382 388 532 4.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 SUPERFAMILY SSF51735 1 108 4.71E-11 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 Gene3D G3DSA:1.10.8.60 540 605 1.1E-21 T 12-10-2018 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 Gene3D G3DSA:3.30.450.20 223 339 1.2E-19 T 12-10-2018 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 Pfam PF02954 Bacterial regulatory protein, Fis family 642 682 2.5E-13 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 Gene3D G3DSA:3.40.50.720 3 123 1.2E-6 T 12-10-2018 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 SMART SM00091 236 301 9.2E-9 T 12-10-2018 IPR000014 PAS domain HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 SMART SM00091 117 183 3.4E-8 T 12-10-2018 IPR000014 PAS domain HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 Pfam PF00158 Sigma-54 interaction domain 368 536 6.9E-67 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 Pfam PF00989 PAS fold 121 218 1.1E-9 T 12-10-2018 IPR013767 PAS fold GO:0006355 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 Pfam PF00989 PAS fold 237 339 1.7E-15 T 12-10-2018 IPR013767 PAS fold GO:0006355 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 SUPERFAMILY SSF55785 217 336 5.93E-17 T 12-10-2018 IPR035965 PAS domain superfamily HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 Gene3D G3DSA:1.10.10.60 609 687 6.8E-16 T 12-10-2018 HW35_03915 96bc3419fb75dd9b04888859ad9dbd44 690 SUPERFAMILY SSF55785 107 215 2.09E-14 T 12-10-2018 IPR035965 PAS domain superfamily HW35_11630 b11556eef15e7c68e4d1513190e25501 506 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 196 506 2.5E-161 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 Pfam PF00958 GMP synthase C terminal domain 414 505 4.1E-45 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 Pfam PF00117 Glutamine amidotransferase class-I 4 184 2.4E-46 T 12-10-2018 IPR017926 Glutamine amidotransferase HW35_11630 b11556eef15e7c68e4d1513190e25501 506 SUPERFAMILY SSF52402 181 399 3.31E-64 T 12-10-2018 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 1.1E-6 T 12-10-2018 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 1.1E-6 T 12-10-2018 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 1.1E-6 T 12-10-2018 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 188 1.8E-83 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 Pfam PF02540 NAD synthase 202 280 2.3E-7 T 12-10-2018 IPR022310 NAD/GMP synthase HW35_11630 b11556eef15e7c68e4d1513190e25501 506 SUPERFAMILY SSF52317 1 221 3.17E-60 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_11630 b11556eef15e7c68e4d1513190e25501 506 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 1.8E-6 T 12-10-2018 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 2 16 1.8E-6 T 12-10-2018 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 1.8E-6 T 12-10-2018 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 Gene3D G3DSA:3.40.50.880 1 193 1.5E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_11630 b11556eef15e7c68e4d1513190e25501 506 SUPERFAMILY SSF54810 386 506 9.81E-52 T 12-10-2018 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 Gene3D G3DSA:3.40.50.620 194 386 8.3E-79 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_11630 b11556eef15e7c68e4d1513190e25501 506 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 1 506 55.371 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 HW35_11630 b11556eef15e7c68e4d1513190e25501 506 Gene3D G3DSA:3.30.300.10 387 506 3.8E-52 T 12-10-2018 HW35_07665 b3c2fe7a26a691a22aa7195b02af71d2 223 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 HW35_07665 b3c2fe7a26a691a22aa7195b02af71d2 223 Gene3D G3DSA:3.40.190.10 6 198 1.0E-78 T 12-10-2018 HW35_07665 b3c2fe7a26a691a22aa7195b02af71d2 223 Pfam PF01634 ATP phosphoribosyltransferase 54 204 7.7E-48 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 HW35_07665 b3c2fe7a26a691a22aa7195b02af71d2 223 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 184 8.5E-62 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 HW35_07665 b3c2fe7a26a691a22aa7195b02af71d2 223 Gene3D G3DSA:3.40.190.10 95 176 1.0E-78 T 12-10-2018 HW35_07665 b3c2fe7a26a691a22aa7195b02af71d2 223 SUPERFAMILY SSF53850 2 207 2.39E-65 T 12-10-2018 HW35_07665 b3c2fe7a26a691a22aa7195b02af71d2 223 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 4 208 55.789 T 12-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 HW35_12565 ea5d5bfff44ba559a3f6c15b74e9aa26 262 Gene3D G3DSA:2.60.120.10 118 257 5.6E-44 T 12-10-2018 IPR014710 RmlC-like jelly roll fold HW35_12565 ea5d5bfff44ba559a3f6c15b74e9aa26 262 Gene3D G3DSA:2.60.120.10 18 117 1.3E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold HW35_12565 ea5d5bfff44ba559a3f6c15b74e9aa26 262 PIRSF PIRSF036628 1 257 1.4E-82 T 12-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 HW35_12565 ea5d5bfff44ba559a3f6c15b74e9aa26 262 Pfam PF04962 KduI/IolB family 10 251 4.7E-63 T 12-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 HW35_12565 ea5d5bfff44ba559a3f6c15b74e9aa26 262 SUPERFAMILY SSF51182 2 237 2.49E-44 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily HW35_09620 279b76fff68efca9ba55c038f4c73da5 166 SUPERFAMILY SSF55620 28 135 2.74E-27 T 12-10-2018 HW35_09620 279b76fff68efca9ba55c038f4c73da5 166 Gene3D G3DSA:3.30.1130.10 22 166 5.1E-67 T 12-10-2018 HW35_09620 279b76fff68efca9ba55c038f4c73da5 166 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 166 70.11 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 HW35_09620 279b76fff68efca9ba55c038f4c73da5 166 Pfam PF14489 QueF-like protein 63 141 1.8E-36 T 12-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 HW35_09620 279b76fff68efca9ba55c038f4c73da5 166 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 28 140 1.6E-52 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 HW35_09620 279b76fff68efca9ba55c038f4c73da5 166 PIRSF PIRSF027377 10 148 2.0E-59 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 HW35_14095 7f6a61d5ac799fb4073cf3177548a546 322 Gene3D G3DSA:3.40.50.300 3 322 2.5E-103 T 12-10-2018 HW35_14095 7f6a61d5ac799fb4073cf3177548a546 322 Pfam PF00005 ABC transporter 33 183 4.0E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_14095 7f6a61d5ac799fb4073cf3177548a546 322 SMART SM00382 41 233 5.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_14095 7f6a61d5ac799fb4073cf3177548a546 322 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_14095 7f6a61d5ac799fb4073cf3177548a546 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 6.1E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_14095 7f6a61d5ac799fb4073cf3177548a546 322 SUPERFAMILY SSF52540 5 255 4.41E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14095 7f6a61d5ac799fb4073cf3177548a546 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 319 1.9E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_09810 f758ecf1159bd96aa982b1df83d37315 483 Pfam PF07501 G5 domain 281 353 1.5E-17 T 12-10-2018 IPR011098 G5 domain HW35_09810 f758ecf1159bd96aa982b1df83d37315 483 Pfam PF01551 Peptidase family M23 383 477 1.1E-34 T 12-10-2018 IPR016047 Peptidase M23 HW35_09810 f758ecf1159bd96aa982b1df83d37315 483 Gene3D G3DSA:3.10.350.10 221 268 3.8E-13 T 12-10-2018 IPR036779 LysM domain superfamily HW35_09810 f758ecf1159bd96aa982b1df83d37315 483 SUPERFAMILY SSF51261 263 480 7.32E-54 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_09810 f758ecf1159bd96aa982b1df83d37315 483 Gene3D G3DSA:2.70.70.10 350 482 1.5E-45 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_09810 f758ecf1159bd96aa982b1df83d37315 483 SMART SM01208 276 354 1.8E-19 T 12-10-2018 IPR011098 G5 domain HW35_09810 f758ecf1159bd96aa982b1df83d37315 483 SUPERFAMILY SSF54106 222 268 1.44E-7 T 12-10-2018 HW35_09810 f758ecf1159bd96aa982b1df83d37315 483 Pfam PF01476 LysM domain 224 267 3.4E-8 T 12-10-2018 IPR018392 LysM domain HW35_09810 f758ecf1159bd96aa982b1df83d37315 483 Gene3D G3DSA:2.20.230.10 277 349 4.7E-14 T 12-10-2018 HW35_09810 f758ecf1159bd96aa982b1df83d37315 483 SMART SM00257 223 268 1.8E-9 T 12-10-2018 IPR018392 LysM domain HW35_16495 61f1c4d0880ef04ee5151535f717f14b 313 Pfam PF01180 Dihydroorotate dehydrogenase 4 286 1.8E-95 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HW35_16495 61f1c4d0880ef04ee5151535f717f14b 313 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 239 259 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 HW35_16495 61f1c4d0880ef04ee5151535f717f14b 313 PIRSF PIRSF000164 1 303 6.1E-87 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 HW35_16495 61f1c4d0880ef04ee5151535f717f14b 313 SUPERFAMILY SSF51395 1 301 6.0E-89 T 12-10-2018 HW35_16495 61f1c4d0880ef04ee5151535f717f14b 313 Gene3D G3DSA:3.20.20.70 1 303 1.5E-98 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_16495 61f1c4d0880ef04ee5151535f717f14b 313 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 HW35_16495 61f1c4d0880ef04ee5151535f717f14b 313 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 302 2.1E-125 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HW35_16495 61f1c4d0880ef04ee5151535f717f14b 313 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 301 41.801 T 12-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 HW35_00695 50949bf3901204b6e8fd5fd474f08bbf 256 SUPERFAMILY SSF52540 12 222 5.58E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_00695 50949bf3901204b6e8fd5fd474f08bbf 256 Pfam PF00005 ABC transporter 32 169 4.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_00695 50949bf3901204b6e8fd5fd474f08bbf 256 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_00695 50949bf3901204b6e8fd5fd474f08bbf 256 SMART SM00382 39 219 3.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_00695 50949bf3901204b6e8fd5fd474f08bbf 256 Gene3D G3DSA:3.40.50.300 10 254 4.1E-61 T 12-10-2018 HW35_03080 adf68da31d00e4ab01484f424e90e298 100 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 5.0E-16 T 12-10-2018 IPR019933 DivIVA domain HW35_03080 adf68da31d00e4ab01484f424e90e298 100 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 3 96 24.4 T 12-10-2018 IPR011229 Cell cycle protein GpsB HW35_03080 adf68da31d00e4ab01484f424e90e298 100 Pfam PF05103 DivIVA protein 8 68 6.5E-17 T 12-10-2018 IPR007793 DivIVA family HW35_03080 adf68da31d00e4ab01484f424e90e298 100 PIRSF PIRSF029938 1 100 3.0E-40 T 12-10-2018 IPR011229 Cell cycle protein GpsB HW35_07620 0517d62c88208cef6fc884d1836ba54b 497 Gene3D G3DSA:1.25.40.10 154 324 4.0E-21 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_07620 0517d62c88208cef6fc884d1836ba54b 497 SMART SM00028 90 123 94.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_07620 0517d62c88208cef6fc884d1836ba54b 497 SMART SM00028 21 54 0.45 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_07620 0517d62c88208cef6fc884d1836ba54b 497 SMART SM00028 187 220 3.5E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_07620 0517d62c88208cef6fc884d1836ba54b 497 SMART SM00028 153 186 270.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_07620 0517d62c88208cef6fc884d1836ba54b 497 Pfam PF05225 helix-turn-helix, Psq domain 456 496 9.7E-7 T 12-10-2018 IPR007889 DNA binding HTH domain, Psq-type GO:0003677 HW35_07620 0517d62c88208cef6fc884d1836ba54b 497 Gene3D G3DSA:1.25.40.10 19 137 4.0E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_07620 0517d62c88208cef6fc884d1836ba54b 497 Pfam PF14559 Tetratricopeptide repeat 163 224 2.3E-7 T 12-10-2018 HW35_07620 0517d62c88208cef6fc884d1836ba54b 497 SUPERFAMILY SSF48452 157 322 1.66E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_07620 0517d62c88208cef6fc884d1836ba54b 497 SUPERFAMILY SSF48452 22 218 3.22E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_08770 2222d03e3fe1245235720a6269570973 323 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 251 1.5E-59 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HW35_08770 2222d03e3fe1245235720a6269570973 323 Gene3D G3DSA:3.90.25.10 183 318 3.2E-127 T 12-10-2018 HW35_08770 2222d03e3fe1245235720a6269570973 323 SUPERFAMILY SSF51735 2 321 5.41E-98 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_08770 2222d03e3fe1245235720a6269570973 323 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 1 321 1.1E-134 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 HW35_08770 2222d03e3fe1245235720a6269570973 323 Gene3D G3DSA:3.40.50.720 2 263 3.2E-127 T 12-10-2018 HW35_15175 0b615bb340fd5a88f309f8ecf0d5f463 269 Gene3D G3DSA:3.40.50.1000 6 260 3.9E-67 T 12-10-2018 IPR023214 HAD superfamily HW35_15175 0b615bb340fd5a88f309f8ecf0d5f463 269 Gene3D G3DSA:3.30.1240.10 86 191 3.9E-67 T 12-10-2018 HW35_15175 0b615bb340fd5a88f309f8ecf0d5f463 269 SUPERFAMILY SSF56784 5 267 8.12E-70 T 12-10-2018 IPR036412 HAD-like superfamily HW35_15175 0b615bb340fd5a88f309f8ecf0d5f463 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 236 4.4E-26 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 HW35_15175 0b615bb340fd5a88f309f8ecf0d5f463 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 263 1.6E-63 T 12-10-2018 IPR000150 Cof family GO:0016787 HW35_15175 0b615bb340fd5a88f309f8ecf0d5f463 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 263 4.2E-67 T 12-10-2018 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 1.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 1.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 1.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 1.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 1.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 1.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 PIRSF PIRSF005419 1 677 3.0E-264 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 Gene3D G3DSA:1.10.8.540 486 575 1.3E-32 T 12-10-2018 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 Pfam PF00771 FHIPEP family 15 667 5.1E-276 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 Gene3D G3DSA:1.10.490.80 576 675 2.5E-22 T 12-10-2018 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 126 149 - T 12-10-2018 IPR025505 FHIPEP conserved site HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 4 675 1.4E-271 T 12-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 HW35_00530 5ae8cc8c88e930a7421105dd3297c837 677 Gene3D G3DSA:3.40.30.60 343 485 5.5E-55 T 12-10-2018 HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 Gene3D G3DSA:3.30.420.40 199 353 1.8E-111 T 12-10-2018 HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 Gene3D G3DSA:3.30.1490.110 87 171 1.8E-111 T 12-10-2018 HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 Gene3D G3DSA:3.30.420.40 10 368 1.8E-111 T 12-10-2018 HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 SUPERFAMILY SSF53067 201 373 6.75E-47 T 12-10-2018 HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 430 30.254 T 12-10-2018 IPR020823 Cell division protein FtsA HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 374 3.6E-123 T 12-10-2018 IPR020823 Cell division protein FtsA HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 Pfam PF02491 SHS2 domain inserted in FTSA 85 164 3.8E-22 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 Pfam PF14450 Cell division protein FtsA 9 191 2.3E-9 T 12-10-2018 HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 SUPERFAMILY SSF53067 6 199 3.6E-52 T 12-10-2018 HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 Pfam PF14450 Cell division protein FtsA 209 370 3.1E-24 T 12-10-2018 HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 Gene3D G3DSA:3.90.640.10 237 302 1.8E-111 T 12-10-2018 HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 PIRSF PIRSF003101 1 430 2.5E-146 T 12-10-2018 IPR020823 Cell division protein FtsA HW35_16360 538ead927fc5b46a348c3a95ce1b9aac 431 SMART SM00842 7 198 5.6E-83 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Gene3D G3DSA:1.10.1420.10 256 552 6.4E-106 T 12-10-2018 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Gene3D G3DSA:3.30.420.110 124 251 2.7E-14 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Pfam PF05192 MutS domain III 262 551 4.3E-46 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Gene3D G3DSA:3.40.1170.10 1 117 3.7E-49 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Gene3D G3DSA:1.10.1420.10 391 527 6.4E-106 T 12-10-2018 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 SUPERFAMILY SSF52540 559 791 3.55E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Pfam PF05190 MutS family domain IV 419 510 3.9E-30 T 12-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 SMART SM00534 600 787 8.2E-121 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 863 0.0 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 SUPERFAMILY SSF48334 257 556 6.02E-94 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 PIRSF PIRSF037677 177 843 2.4E-131 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 PIRSF PIRSF037677 1 179 1.7E-34 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 SUPERFAMILY SSF53150 114 270 1.01E-30 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Pfam PF00488 MutS domain V 604 790 1.5E-84 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 857 25.925 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Gene3D G3DSA:3.40.50.300 560 851 2.9E-105 T 12-10-2018 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Pfam PF05188 MutS domain II 125 225 5.4E-11 T 12-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 Pfam PF01624 MutS domain I 5 116 1.3E-46 T 12-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 681 697 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 SUPERFAMILY SSF55271 2 112 2.35E-42 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 HW35_17120 2b33b7babdcb9c54ea8e663a7efc91f2 867 SMART SM00533 274 583 2.1E-113 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HW35_03675 a0afc0cec57b522eb5a3acc25d410410 146 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 36.907 T 12-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 HW35_03675 a0afc0cec57b522eb5a3acc25d410410 146 Gene3D G3DSA:3.30.565.10 1 143 8.7E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_03675 a0afc0cec57b522eb5a3acc25d410410 146 SMART SM00387 35 140 2.6E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_03675 a0afc0cec57b522eb5a3acc25d410410 146 Pfam PF13581 Histidine kinase-like ATPase domain 10 136 2.2E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_03675 a0afc0cec57b522eb5a3acc25d410410 146 SUPERFAMILY SSF55874 28 135 9.69E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_03675 a0afc0cec57b522eb5a3acc25d410410 146 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 2 137 4.6E-71 T 12-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 HW35_16320 e225e9d093f891ff6d1483b6ac9a73e5 450 Gene3D G3DSA:3.40.1190.10 102 308 3.1E-66 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HW35_16320 e225e9d093f891ff6d1483b6ac9a73e5 450 Gene3D G3DSA:3.90.190.20 315 448 3.9E-42 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HW35_16320 e225e9d093f891ff6d1483b6ac9a73e5 450 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 447 1.7E-135 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HW35_16320 e225e9d093f891ff6d1483b6ac9a73e5 450 SUPERFAMILY SSF53244 310 449 1.01E-42 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HW35_16320 e225e9d093f891ff6d1483b6ac9a73e5 450 Pfam PF08245 Mur ligase middle domain 117 291 1.7E-32 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 HW35_16320 e225e9d093f891ff6d1483b6ac9a73e5 450 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 449 36.804 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HW35_16320 e225e9d093f891ff6d1483b6ac9a73e5 450 Gene3D G3DSA:3.40.50.720 10 95 2.5E-32 T 12-10-2018 HW35_16320 e225e9d093f891ff6d1483b6ac9a73e5 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 378 3.5E-9 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 HW35_16320 e225e9d093f891ff6d1483b6ac9a73e5 450 SUPERFAMILY SSF51984 10 100 1.22E-18 T 12-10-2018 HW35_16320 e225e9d093f891ff6d1483b6ac9a73e5 450 SUPERFAMILY SSF53623 103 308 2.62E-52 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 2.6E-14 T 12-10-2018 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 2.6E-14 T 12-10-2018 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 2.6E-14 T 12-10-2018 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 4.4E-8 T 12-10-2018 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 4.4E-8 T 12-10-2018 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 4.0E-71 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 Gene3D G3DSA:3.40.50.880 1 189 1.2E-64 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 SUPERFAMILY SSF52317 1 194 4.75E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 Pfam PF00117 Glutamine amidotransferase class-I 3 188 8.2E-56 T 12-10-2018 IPR017926 Glutamine amidotransferase HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.8E-32 T 12-10-2018 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.8E-32 T 12-10-2018 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.8E-32 T 12-10-2018 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00097 Anthranilate synthase component II signature 165 178 1.8E-32 T 12-10-2018 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.8E-32 T 12-10-2018 HW35_02565 30b26d106dd2c163c4edfaf92c162a77 203 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.8E-32 T 12-10-2018 HW35_04470 27633bdb409a3e6fd48996e2d12d6153 133 Gene3D G3DSA:3.40.140.10 1 132 8.8E-60 T 12-10-2018 HW35_04470 27633bdb409a3e6fd48996e2d12d6153 133 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HW35_04470 27633bdb409a3e6fd48996e2d12d6153 133 SUPERFAMILY SSF53927 2 130 1.29E-49 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 HW35_04470 27633bdb409a3e6fd48996e2d12d6153 133 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 130 6.0E-47 T 12-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 HW35_04470 27633bdb409a3e6fd48996e2d12d6153 133 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 102 6.3E-16 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain HW35_16695 be2b1874c5ab3baee9a3e0bd4edb21ff 172 Pfam PF05239 PRC-barrel domain 97 171 4.5E-14 T 12-10-2018 IPR027275 PRC-barrel domain HW35_16695 be2b1874c5ab3baee9a3e0bd4edb21ff 172 Gene3D G3DSA:2.30.30.240 95 172 7.9E-22 T 12-10-2018 HW35_16695 be2b1874c5ab3baee9a3e0bd4edb21ff 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 170 9.9E-52 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 HW35_16695 be2b1874c5ab3baee9a3e0bd4edb21ff 172 Pfam PF01782 RimM N-terminal domain 7 91 2.1E-22 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 HW35_16695 be2b1874c5ab3baee9a3e0bd4edb21ff 172 SUPERFAMILY SSF50447 4 92 2.12E-21 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_16695 be2b1874c5ab3baee9a3e0bd4edb21ff 172 SUPERFAMILY SSF50346 100 170 1.81E-20 T 12-10-2018 IPR011033 PRC-barrel-like superfamily HW35_16695 be2b1874c5ab3baee9a3e0bd4edb21ff 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 170 24.388 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 HW35_16695 be2b1874c5ab3baee9a3e0bd4edb21ff 172 Gene3D G3DSA:2.40.30.60 5 92 6.8E-20 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 HW35_07205 ef9e4b771205d766a6fe9c3fccbbea20 252 Pfam PF16285 Domain of unknown function (DUF4931) 8 252 1.3E-111 T 12-10-2018 HW35_07205 ef9e4b771205d766a6fe9c3fccbbea20 252 SUPERFAMILY SSF54197 13 128 2.65E-23 T 12-10-2018 IPR036265 HIT-like superfamily HW35_07205 ef9e4b771205d766a6fe9c3fccbbea20 252 Gene3D G3DSA:3.30.428.10 56 130 1.8E-11 T 12-10-2018 IPR036265 HIT-like superfamily HW35_07205 ef9e4b771205d766a6fe9c3fccbbea20 252 PIRSF PIRSF031505 1 252 1.2E-87 T 12-10-2018 IPR012361 Galactose-1-phosphate uridylyltransferase, short form, putative HW35_13570 fe5bebb66c20ab0e149cdef98fadfe16 383 Gene3D G3DSA:3.40.50.300 2 207 2.0E-61 T 12-10-2018 HW35_13570 fe5bebb66c20ab0e149cdef98fadfe16 383 Gene3D G3DSA:3.40.50.300 216 383 5.6E-44 T 12-10-2018 HW35_13570 fe5bebb66c20ab0e149cdef98fadfe16 383 SMART SM00487 22 220 1.3E-53 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_13570 fe5bebb66c20ab0e149cdef98fadfe16 383 SUPERFAMILY SSF52540 72 356 2.17E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13570 fe5bebb66c20ab0e149cdef98fadfe16 383 SMART SM00490 255 336 5.3E-31 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_13570 fe5bebb66c20ab0e149cdef98fadfe16 383 Pfam PF00270 DEAD/DEAH box helicase 28 193 2.0E-43 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HW35_13570 fe5bebb66c20ab0e149cdef98fadfe16 383 Pfam PF00271 Helicase conserved C-terminal domain 229 336 3.5E-29 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_01950 f41a9eb380270012914073bf1a02bafc 94 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 11 82 3.3E-11 T 12-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 HW35_01950 f41a9eb380270012914073bf1a02bafc 94 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 1 93 3.2E-35 T 12-10-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 HW35_15670 e97c5d5ef7e359f172282ae3937a6772 394 Gene3D G3DSA:3.90.1200.10 120 394 3.6E-104 T 12-10-2018 HW35_15670 e97c5d5ef7e359f172282ae3937a6772 394 Gene3D G3DSA:3.30.200.20 1 119 1.5E-46 T 12-10-2018 HW35_15670 e97c5d5ef7e359f172282ae3937a6772 394 Pfam PF01636 Phosphotransferase enzyme family 35 268 1.4E-14 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase HW35_15670 e97c5d5ef7e359f172282ae3937a6772 394 PIRSF PIRSF031134 6 394 5.9E-154 T 12-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 HW35_15670 e97c5d5ef7e359f172282ae3937a6772 394 SUPERFAMILY SSF56112 9 393 1.48E-87 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_15670 e97c5d5ef7e359f172282ae3937a6772 394 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 394 173.245 T 12-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 HW35_15670 e97c5d5ef7e359f172282ae3937a6772 394 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 36 393 5.2E-142 T 12-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 HW35_09280 33e310f068b381b7c81e3cba090d735c 283 Gene3D G3DSA:1.10.1040.10 193 278 1.5E-36 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HW35_09280 33e310f068b381b7c81e3cba090d735c 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 5.3E-69 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 HW35_09280 33e310f068b381b7c81e3cba090d735c 283 SUPERFAMILY SSF48179 185 283 3.06E-34 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_09280 33e310f068b381b7c81e3cba090d735c 283 Gene3D G3DSA:3.40.50.720 1 188 1.7E-74 T 12-10-2018 HW35_09280 33e310f068b381b7c81e3cba090d735c 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 1.7E-36 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 HW35_09280 33e310f068b381b7c81e3cba090d735c 283 SUPERFAMILY SSF51735 1 185 1.53E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_09280 33e310f068b381b7c81e3cba090d735c 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 12-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 HW35_09280 33e310f068b381b7c81e3cba090d735c 283 PIRSF PIRSF000105 1 283 8.4E-94 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 HW35_06205 e6e2f8cc6a908a41c3584918be2efb5c 259 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 251 2.1E-61 T 12-10-2018 HW35_06205 e6e2f8cc6a908a41c3584918be2efb5c 259 ProSitePatterns PS01229 Hypothetical cof family signature 2. 207 229 - T 12-10-2018 HW35_06205 e6e2f8cc6a908a41c3584918be2efb5c 259 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 226 1.7E-21 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 HW35_06205 e6e2f8cc6a908a41c3584918be2efb5c 259 SUPERFAMILY SSF56784 6 254 1.44E-66 T 12-10-2018 IPR036412 HAD-like superfamily HW35_06205 e6e2f8cc6a908a41c3584918be2efb5c 259 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 252 1.8E-60 T 12-10-2018 IPR000150 Cof family GO:0016787 HW35_06205 e6e2f8cc6a908a41c3584918be2efb5c 259 Gene3D G3DSA:3.30.1240.10 82 182 8.0E-79 T 12-10-2018 HW35_06205 e6e2f8cc6a908a41c3584918be2efb5c 259 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 12-10-2018 HW35_06205 e6e2f8cc6a908a41c3584918be2efb5c 259 Gene3D G3DSA:3.40.50.1000 6 249 8.0E-79 T 12-10-2018 IPR023214 HAD superfamily HW35_05365 9ebd9c51bdbc73f62b04879c719a8946 270 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 214 2.0E-40 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HW35_05365 9ebd9c51bdbc73f62b04879c719a8946 270 Gene3D G3DSA:3.40.50.1860 5 253 8.3E-100 T 12-10-2018 HW35_05365 9ebd9c51bdbc73f62b04879c719a8946 270 Hamap MF_00258 Glutamate racemase [murI]. 3 255 41.172 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HW35_05365 9ebd9c51bdbc73f62b04879c719a8946 270 SUPERFAMILY SSF53681 4 106 3.6E-37 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HW35_05365 9ebd9c51bdbc73f62b04879c719a8946 270 SUPERFAMILY SSF53681 109 262 2.29E-40 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HW35_05365 9ebd9c51bdbc73f62b04879c719a8946 270 Gene3D G3DSA:3.40.50.1860 94 206 8.3E-100 T 12-10-2018 HW35_05365 9ebd9c51bdbc73f62b04879c719a8946 270 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 253 1.6E-89 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HW35_05365 9ebd9c51bdbc73f62b04879c719a8946 270 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 12-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HW35_05365 9ebd9c51bdbc73f62b04879c719a8946 270 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 69 77 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HW35_11560 990d3d6f0e8deeea93cca505fd1c90cb 162 Gene3D G3DSA:3.30.70.640 1 162 1.7E-69 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_11560 990d3d6f0e8deeea93cca505fd1c90cb 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 161 36.099 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_11560 990d3d6f0e8deeea93cca505fd1c90cb 162 SUPERFAMILY SSF55040 11 158 3.14E-59 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_11560 990d3d6f0e8deeea93cca505fd1c90cb 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 155 2.9E-66 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_11560 990d3d6f0e8deeea93cca505fd1c90cb 162 Pfam PF01967 MoaC family 15 153 6.6E-55 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HW35_04355 a9f8776262ce61785e5edbe32c0ec63e 137 Gene3D G3DSA:1.10.10.10 1 83 5.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_04355 a9f8776262ce61785e5edbe32c0ec63e 137 Pfam PF01475 Ferric uptake regulator family 12 129 1.5E-29 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 HW35_04355 a9f8776262ce61785e5edbe32c0ec63e 137 Gene3D G3DSA:3.30.1490.190 87 137 1.5E-13 T 12-10-2018 HW35_04355 a9f8776262ce61785e5edbe32c0ec63e 137 SUPERFAMILY SSF46785 5 134 6.81E-36 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_03730 6b40f3a6ad2a2355a54044c62ff66b1b 105 SUPERFAMILY SSF46689 3 99 3.23E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_00605 6b40f3a6ad2a2355a54044c62ff66b1b 105 SUPERFAMILY SSF46689 3 99 3.23E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_05085 302d705a8e1ddbe421bfdc0f6735e31e 293 PIRSF PIRSF038471 1 287 1.9E-67 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 HW35_05085 302d705a8e1ddbe421bfdc0f6735e31e 293 Gene3D G3DSA:1.20.5.490 77 114 5.3E-6 T 12-10-2018 HW35_05085 302d705a8e1ddbe421bfdc0f6735e31e 293 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 6 278 1.9E-63 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 HW35_05085 302d705a8e1ddbe421bfdc0f6735e31e 293 Gene3D G3DSA:2.40.10.340 115 185 3.5E-25 T 12-10-2018 HW35_05085 302d705a8e1ddbe421bfdc0f6735e31e 293 Gene3D G3DSA:2.40.10.350 186 261 4.0E-30 T 12-10-2018 HW35_05085 302d705a8e1ddbe421bfdc0f6735e31e 293 Pfam PF04085 rod shape-determining protein MreC 123 274 1.2E-45 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 HW35_03220 b0e99588fe620c95ea245e761ccedd38 278 PIRSF PIRSF000388 1 266 1.1E-112 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HW35_03220 b0e99588fe620c95ea245e761ccedd38 278 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2 263 2.9E-117 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HW35_03220 b0e99588fe620c95ea245e761ccedd38 278 Gene3D G3DSA:3.20.20.60 3 274 1.5E-117 T 12-10-2018 HW35_03220 b0e99588fe620c95ea245e761ccedd38 278 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 259 7.7E-115 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HW35_03220 b0e99588fe620c95ea245e761ccedd38 278 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 263 43.804 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HW35_03220 b0e99588fe620c95ea245e761ccedd38 278 SUPERFAMILY SSF51621 3 263 2.59E-110 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 HW35_11840 b8409f7716cc42ed73c048ae3ab3c2d9 492 Pfam PF00474 Sodium:solute symporter family 35 434 4.3E-110 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 HW35_11840 b8409f7716cc42ed73c048ae3ab3c2d9 492 Gene3D G3DSA:1.20.1730.10 23 490 8.8E-97 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily HW35_11840 b8409f7716cc42ed73c048ae3ab3c2d9 492 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 434 5.9E-100 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 HW35_11840 b8409f7716cc42ed73c048ae3ab3c2d9 492 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 416 436 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site HW35_11840 b8409f7716cc42ed73c048ae3ab3c2d9 492 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 8 485 7.5E-219 T 12-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 HW35_11840 b8409f7716cc42ed73c048ae3ab3c2d9 492 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 SUPERFAMILY SSF51905 3 343 1.11E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 472 6.5E-180 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 SUPERFAMILY SSF55424 351 472 1.39E-40 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 3.0E-64 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PIRSF PIRSF000350 1 470 1.7E-84 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.4E-37 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.4E-37 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.4E-37 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 1.4E-37 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.4E-37 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 Gene3D G3DSA:3.50.50.60 163 285 7.4E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 Gene3D G3DSA:3.30.390.30 353 473 1.5E-46 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 6.4E-38 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 Gene3D G3DSA:3.50.50.60 5 339 7.4E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 3.4E-67 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 3.4E-67 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 3.4E-67 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 3.4E-67 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 3.4E-67 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 3.4E-67 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 3.4E-67 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.4E-67 T 12-10-2018 HW35_03895 030b149c7fe3c05ae45c6982ad851f74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.4E-67 T 12-10-2018 HW35_04215 21094c3d926a3917c5d25707938e2188 82 Pfam PF11117 Protein of unknown function (DUF2626) 1 74 1.7E-36 T 12-10-2018 IPR020254 Protein of unknown function DUF2626 HW35_04215 21094c3d926a3917c5d25707938e2188 82 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 80 8.0E-29 T 12-10-2018 IPR020254 Protein of unknown function DUF2626 HW35_13300 afcf18edd7c03bf49f869f2219e1b57d 173 Gene3D G3DSA:3.30.70.1150 84 162 2.4E-27 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal HW35_13300 afcf18edd7c03bf49f869f2219e1b57d 173 SUPERFAMILY SSF55021 1 77 3.38E-19 T 12-10-2018 HW35_13300 afcf18edd7c03bf49f869f2219e1b57d 173 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 158 1.1E-61 T 12-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 HW35_13300 afcf18edd7c03bf49f869f2219e1b57d 173 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-27 T 12-10-2018 HW35_13300 afcf18edd7c03bf49f869f2219e1b57d 173 SUPERFAMILY SSF55021 80 160 2.44E-25 T 12-10-2018 HW35_13300 afcf18edd7c03bf49f869f2219e1b57d 173 Gene3D G3DSA:3.30.70.260 1 80 3.0E-29 T 12-10-2018 HW35_13300 afcf18edd7c03bf49f869f2219e1b57d 173 Pfam PF10369 Small subunit of acetolactate synthase 85 158 1.7E-27 T 12-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 HW35_13300 afcf18edd7c03bf49f869f2219e1b57d 173 Pfam PF01842 ACT domain 4 68 1.0E-14 T 12-10-2018 IPR002912 ACT domain HW35_10930 7cc93b5a10737046dddd145dc5b7d380 227 SUPERFAMILY SSF52540 1 220 1.36E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10930 7cc93b5a10737046dddd145dc5b7d380 227 Gene3D G3DSA:3.40.50.300 1 225 7.1E-68 T 12-10-2018 HW35_10930 7cc93b5a10737046dddd145dc5b7d380 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_10930 7cc93b5a10737046dddd145dc5b7d380 227 SMART SM00382 30 219 2.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_10930 7cc93b5a10737046dddd145dc5b7d380 227 Pfam PF00005 ABC transporter 21 169 2.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_16610 3d4f8c9c8c8b6e530b7232ff62d6eeb4 560 SMART SM01121 240 560 6.9E-190 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain HW35_16610 3d4f8c9c8c8b6e530b7232ff62d6eeb4 560 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 560 4.6E-220 T 12-10-2018 IPR019986 DAK2 domain-containing protein YloV HW35_16610 3d4f8c9c8c8b6e530b7232ff62d6eeb4 560 SUPERFAMILY SSF101473 3 200 1.44E-45 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 HW35_16610 3d4f8c9c8c8b6e530b7232ff62d6eeb4 560 Pfam PF13684 Dihydroxyacetone kinase family 241 560 1.3E-128 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain HW35_16610 3d4f8c9c8c8b6e530b7232ff62d6eeb4 560 SMART SM01120 36 201 1.1E-71 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 HW35_16610 3d4f8c9c8c8b6e530b7232ff62d6eeb4 560 Gene3D G3DSA:1.25.40.340 5 179 4.8E-11 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 HW35_16610 3d4f8c9c8c8b6e530b7232ff62d6eeb4 560 Pfam PF02734 DAK2 domain 36 200 1.6E-41 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 HW35_07595 fb0c30b7e6b1d6f99dd1762ed4495ed8 316 Pfam PF02650 WhiA C-terminal HTH domain 220 304 1.9E-35 T 12-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal HW35_07595 fb0c30b7e6b1d6f99dd1762ed4495ed8 316 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 1.8E-132 T 12-10-2018 IPR033981 Sporulation regulator WhiA-like HW35_07595 fb0c30b7e6b1d6f99dd1762ed4495ed8 316 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 35.659 T 12-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 HW35_07595 fb0c30b7e6b1d6f99dd1762ed4495ed8 316 Gene3D G3DSA:3.10.28.10 1 214 5.0E-69 T 12-10-2018 IPR027434 Homing endonuclease HW35_07595 fb0c30b7e6b1d6f99dd1762ed4495ed8 316 Gene3D G3DSA:1.10.10.10 215 309 1.9E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_07595 fb0c30b7e6b1d6f99dd1762ed4495ed8 316 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 1.8E-37 T 12-10-2018 IPR039518 WhiA, LAGLIDADG-like domain HW35_07595 fb0c30b7e6b1d6f99dd1762ed4495ed8 316 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 18 103 2.0E-36 T 12-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain HW35_07595 fb0c30b7e6b1d6f99dd1762ed4495ed8 316 SUPERFAMILY SSF55608 120 221 1.11E-21 T 12-10-2018 IPR027434 Homing endonuclease HW35_11080 9d1895da39865db0085bbe5a4760b6d3 418 Gene3D G3DSA:2.170.120.30 38 138 5.6E-28 T 12-10-2018 HW35_11080 9d1895da39865db0085bbe5a4760b6d3 418 Gene3D G3DSA:2.170.120.30 319 418 6.7E-19 T 12-10-2018 HW35_11080 9d1895da39865db0085bbe5a4760b6d3 418 Pfam PF07949 YbbR-like protein 334 413 2.7E-5 T 12-10-2018 IPR012505 YbbR-like HW35_11080 9d1895da39865db0085bbe5a4760b6d3 418 Pfam PF07949 YbbR-like protein 138 223 5.0E-9 T 12-10-2018 IPR012505 YbbR-like HW35_11080 9d1895da39865db0085bbe5a4760b6d3 418 Pfam PF07949 YbbR-like protein 50 130 2.2E-11 T 12-10-2018 IPR012505 YbbR-like HW35_11080 9d1895da39865db0085bbe5a4760b6d3 418 Pfam PF07949 YbbR-like protein 232 310 3.0E-10 T 12-10-2018 IPR012505 YbbR-like HW35_11080 9d1895da39865db0085bbe5a4760b6d3 418 Gene3D G3DSA:2.170.120.40 139 227 1.2E-7 T 12-10-2018 HW35_11080 9d1895da39865db0085bbe5a4760b6d3 418 Gene3D G3DSA:2.170.120.40 229 313 3.1E-15 T 12-10-2018 HW35_00915 7f80cf461234c39393757bfe5b54be8d 396 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 HW35_00915 7f80cf461234c39393757bfe5b54be8d 396 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 10 396 3.9E-197 T 12-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type HW35_00915 7f80cf461234c39393757bfe5b54be8d 396 Pfam PF00155 Aminotransferase class I and II 43 383 1.7E-67 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HW35_00915 7f80cf461234c39393757bfe5b54be8d 396 Gene3D G3DSA:3.90.1150.10 38 387 6.0E-140 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_00915 7f80cf461234c39393757bfe5b54be8d 396 Gene3D G3DSA:3.40.640.10 58 294 6.0E-140 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_00915 7f80cf461234c39393757bfe5b54be8d 396 SUPERFAMILY SSF53383 7 394 5.17E-113 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_06320 30f88d2168b2d3042ba67769510535ff 320 PRINTS PR00723 Subtilisin serine protease family (S8) signature 241 257 1.1E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_06320 30f88d2168b2d3042ba67769510535ff 320 PRINTS PR00723 Subtilisin serine protease family (S8) signature 82 95 1.1E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_06320 30f88d2168b2d3042ba67769510535ff 320 PRINTS PR00723 Subtilisin serine protease family (S8) signature 40 59 1.1E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_06320 30f88d2168b2d3042ba67769510535ff 320 SUPERFAMILY SSF52743 21 286 4.84E-88 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 HW35_06320 30f88d2168b2d3042ba67769510535ff 320 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 86 96 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site HW35_06320 30f88d2168b2d3042ba67769510535ff 320 Gene3D G3DSA:3.40.50.200 3 306 1.5E-113 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 HW35_06320 30f88d2168b2d3042ba67769510535ff 320 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 45 56 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site HW35_06320 30f88d2168b2d3042ba67769510535ff 320 Pfam PF00082 Subtilase family 40 290 1.5E-61 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HW35_06320 30f88d2168b2d3042ba67769510535ff 320 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 242 252 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site HW35_03245 df0573fb98fabc9b9b7341d30bec131e 139 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 61 - T 12-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 HW35_03245 df0573fb98fabc9b9b7341d30bec131e 139 SMART SM00851 14 107 8.4E-23 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain HW35_03245 df0573fb98fabc9b9b7341d30bec131e 139 SUPERFAMILY SSF52335 1 132 3.53E-53 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HW35_03245 df0573fb98fabc9b9b7341d30bec131e 139 Gene3D G3DSA:3.40.50.1380 1 137 4.9E-57 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HW35_03245 df0573fb98fabc9b9b7341d30bec131e 139 Pfam PF02142 MGS-like domain 15 107 4.2E-19 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain HW35_03245 df0573fb98fabc9b9b7341d30bec131e 139 PIRSF PIRSF006614 1 139 4.8E-62 T 12-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 HW35_03245 df0573fb98fabc9b9b7341d30bec131e 139 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 2 120 1.6E-59 T 12-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 HW35_03245 df0573fb98fabc9b9b7341d30bec131e 139 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 33.745 T 12-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 HW35_12625 6fe0e19e5b0c8aeeab26eb52df4971b5 480 TIGRFAM TIGR02119 panF: sodium/pantothenate symporter 3 471 4.8E-210 T 12-10-2018 IPR011849 Sodium/pantothenate symporter GO:0015081|GO:0015233|GO:0015887|GO:0016021|GO:0036376 HW35_12625 6fe0e19e5b0c8aeeab26eb52df4971b5 480 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 37 432 1.8E-90 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 HW35_12625 6fe0e19e5b0c8aeeab26eb52df4971b5 480 Gene3D G3DSA:1.20.1730.10 2 479 9.3E-83 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily HW35_12625 6fe0e19e5b0c8aeeab26eb52df4971b5 480 Pfam PF00474 Sodium:solute symporter family 37 432 3.8E-101 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 HW35_12625 6fe0e19e5b0c8aeeab26eb52df4971b5 480 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 156 181 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site HW35_05565 ca4df6d16b365647b0eb66417c5ef1f6 66 Pfam PF01632 Ribosomal protein L35 2 62 7.0E-27 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05565 ca4df6d16b365647b0eb66417c5ef1f6 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 1.3E-27 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HW35_05565 ca4df6d16b365647b0eb66417c5ef1f6 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.8E-22 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HW35_05565 ca4df6d16b365647b0eb66417c5ef1f6 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.8E-22 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HW35_05565 ca4df6d16b365647b0eb66417c5ef1f6 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.8E-22 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HW35_05565 ca4df6d16b365647b0eb66417c5ef1f6 66 Gene3D G3DSA:2.40.50.530 1 63 3.5E-23 T 12-10-2018 HW35_05565 ca4df6d16b365647b0eb66417c5ef1f6 66 SUPERFAMILY SSF143034 2 62 3.01E-23 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05565 ca4df6d16b365647b0eb66417c5ef1f6 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.147 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HW35_05565 ca4df6d16b365647b0eb66417c5ef1f6 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_06095 8c24b9f16545504f156c26334218865b 543 Pfam PF01943 Polysaccharide biosynthesis protein 5 316 5.8E-47 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HW35_06095 8c24b9f16545504f156c26334218865b 543 PIRSF PIRSF038958 1 533 4.9E-125 T 12-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type HW35_06095 8c24b9f16545504f156c26334218865b 543 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 368 515 1.7E-26 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 Pfam PF00005 ABC transporter 18 163 2.7E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 13 365 7.2E-122 T 12-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 SMART SM00116 257 305 1.3E-5 T 12-10-2018 IPR000644 CBS domain HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 SMART SM00116 316 364 3.5E-7 T 12-10-2018 IPR000644 CBS domain HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 SMART SM00382 26 213 1.1E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 SUPERFAMILY SSF54631 248 365 8.46E-29 T 12-10-2018 HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 Gene3D G3DSA:3.10.580.10 249 369 2.0E-29 T 12-10-2018 HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 SUPERFAMILY SSF52540 1 241 4.43E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 Pfam PF00571 CBS domain 250 299 4.0E-9 T 12-10-2018 IPR000644 CBS domain HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 Pfam PF00571 CBS domain 310 364 4.5E-8 T 12-10-2018 IPR000644 CBS domain HW35_02330 75d2ced288a24985e0d2afbeb880db25 374 Gene3D G3DSA:3.40.50.300 1 240 1.1E-78 T 12-10-2018 HW35_03815 ab3b3ea4e3220883bdabaf35105457d6 280 SUPERFAMILY SSF48179 161 268 1.7E-35 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_03815 ab3b3ea4e3220883bdabaf35105457d6 280 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 1.4E-38 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HW35_03815 ab3b3ea4e3220883bdabaf35105457d6 280 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 265 8.3E-86 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HW35_03815 ab3b3ea4e3220883bdabaf35105457d6 280 Gene3D G3DSA:1.10.3730.10 165 270 3.4E-41 T 12-10-2018 HW35_03815 ab3b3ea4e3220883bdabaf35105457d6 280 Gene3D G3DSA:3.40.50.720 1 164 1.8E-48 T 12-10-2018 HW35_03815 ab3b3ea4e3220883bdabaf35105457d6 280 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 266 26.74 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HW35_03815 ab3b3ea4e3220883bdabaf35105457d6 280 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 99 5.2E-19 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal HW35_03815 ab3b3ea4e3220883bdabaf35105457d6 280 SUPERFAMILY SSF51735 2 160 5.73E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_03815 ab3b3ea4e3220883bdabaf35105457d6 280 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HW35_03815 ab3b3ea4e3220883bdabaf35105457d6 280 PIRSF PIRSF000193 1 269 9.3E-82 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HW35_11760 9a57f51a6e0b22f459cd17cfd6f7873d 227 SUPERFAMILY SSF51395 5 223 2.2E-56 T 12-10-2018 HW35_11760 9a57f51a6e0b22f459cd17cfd6f7873d 227 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 8 223 1.5E-80 T 12-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 HW35_11760 9a57f51a6e0b22f459cd17cfd6f7873d 227 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 29.211 T 12-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 HW35_11760 9a57f51a6e0b22f459cd17cfd6f7873d 227 Pfam PF01884 PcrB family 2 225 3.0E-88 T 12-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 HW35_11760 9a57f51a6e0b22f459cd17cfd6f7873d 227 Gene3D G3DSA:3.20.20.390 1 227 1.5E-98 T 12-10-2018 IPR038597 GGGP/HepGP synthase superfamily HW35_00400 6152ff0de4f87b2aa1e794ba8bacad27 673 SUPERFAMILY SSF103190 109 201 1.06E-12 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily HW35_00400 6152ff0de4f87b2aa1e794ba8bacad27 673 Pfam PF02743 Cache domain 48 276 2.1E-38 T 12-10-2018 IPR033479 Double Cache domain 1 HW35_00400 6152ff0de4f87b2aa1e794ba8bacad27 673 SMART SM00283 396 671 8.7E-52 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HW35_00400 6152ff0de4f87b2aa1e794ba8bacad27 673 Gene3D G3DSA:3.30.450.20 86 192 2.3E-40 T 12-10-2018 HW35_00400 6152ff0de4f87b2aa1e794ba8bacad27 673 SMART SM00304 315 367 4.3E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_00400 6152ff0de4f87b2aa1e794ba8bacad27 673 SUPERFAMILY SSF58104 335 671 3.66E-66 T 12-10-2018 HW35_00400 6152ff0de4f87b2aa1e794ba8bacad27 673 Gene3D G3DSA:1.10.287.950 366 671 1.2E-62 T 12-10-2018 HW35_00400 6152ff0de4f87b2aa1e794ba8bacad27 673 Gene3D G3DSA:3.30.450.20 193 287 2.3E-40 T 12-10-2018 HW35_00400 6152ff0de4f87b2aa1e794ba8bacad27 673 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 461 624 8.7E-37 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HW35_14620 7b630238fd80fb395f16ba86f3ca7430 245 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 44.249 T 12-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 HW35_14620 7b630238fd80fb395f16ba86f3ca7430 245 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 12-10-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 HW35_14620 7b630238fd80fb395f16ba86f3ca7430 245 SUPERFAMILY SSF100950 1 243 8.9E-95 T 12-10-2018 IPR037171 NagB/RpiA transferase-like HW35_14620 7b630238fd80fb395f16ba86f3ca7430 245 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 243 2.3E-95 T 12-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 HW35_14620 7b630238fd80fb395f16ba86f3ca7430 245 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 225 1.3E-20 T 12-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 HW35_14620 7b630238fd80fb395f16ba86f3ca7430 245 Gene3D G3DSA:3.40.50.1360 1 245 2.6E-100 T 12-10-2018 HW35_16375 42a8d80d05238e3c4e3985e6aaa9ec9e 419 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 2.2E-134 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_16375 42a8d80d05238e3c4e3985e6aaa9ec9e 419 SUPERFAMILY SSF56672 17 346 6.23E-62 T 12-10-2018 HW35_16375 42a8d80d05238e3c4e3985e6aaa9ec9e 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 1.6E-8 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_16375 42a8d80d05238e3c4e3985e6aaa9ec9e 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 1.6E-8 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_16375 42a8d80d05238e3c4e3985e6aaa9ec9e 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 1.6E-8 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_16375 42a8d80d05238e3c4e3985e6aaa9ec9e 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 205 218 1.6E-8 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_16375 42a8d80d05238e3c4e3985e6aaa9ec9e 419 Pfam PF08388 Group II intron, maturase-specific domain 288 359 2.8E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_16375 42a8d80d05238e3c4e3985e6aaa9ec9e 419 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 1.1E-47 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_13430 019082367fbc9132453f8cf06768e952 248 SMART SM00448 2 113 1.5E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_13430 019082367fbc9132453f8cf06768e952 248 Gene3D G3DSA:2.20.25.10 211 248 3.9E-11 T 12-10-2018 HW35_13430 019082367fbc9132453f8cf06768e952 248 Pfam PF00072 Response regulator receiver domain 5 113 3.7E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_13430 019082367fbc9132453f8cf06768e952 248 SMART SM00850 150 247 1.1E-35 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 HW35_13430 019082367fbc9132453f8cf06768e952 248 SUPERFAMILY SSF52172 3 119 1.85E-28 T 12-10-2018 IPR011006 CheY-like superfamily HW35_13430 019082367fbc9132453f8cf06768e952 248 Gene3D G3DSA:2.40.50.40 142 209 2.9E-13 T 12-10-2018 HW35_13430 019082367fbc9132453f8cf06768e952 248 Gene3D G3DSA:3.40.50.2300 1 127 1.5E-31 T 12-10-2018 HW35_13430 019082367fbc9132453f8cf06768e952 248 Pfam PF04397 LytTr DNA-binding domain 151 246 2.7E-31 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 HW35_08180 d9addc6719b9d0484365f6f6cbca4fc9 433 Pfam PF00860 Permease family 14 394 5.7E-67 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 HW35_08180 d9addc6719b9d0484365f6f6cbca4fc9 433 PIRSF PIRSF005353 1 433 3.5E-172 T 12-10-2018 IPR026033 Purine permease PbuG-like HW35_05325 801f25bf4d49519eaa800b62bd1f4406 281 Pfam PF13276 HTH-like domain 35 90 1.1E-10 T 12-10-2018 IPR025948 HTH-like domain HW35_05325 801f25bf4d49519eaa800b62bd1f4406 281 SUPERFAMILY SSF53098 119 271 2.88E-22 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_05325 801f25bf4d49519eaa800b62bd1f4406 281 Pfam PF00665 Integrase core domain 121 233 1.1E-16 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_07455 1874b46115075afcfe8688fecacf48ba 248 SUPERFAMILY SSF53448 2 206 1.48E-34 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_07455 1874b46115075afcfe8688fecacf48ba 248 Gene3D G3DSA:3.90.550.10 2 214 2.6E-48 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_07455 1874b46115075afcfe8688fecacf48ba 248 Pfam PF02348 Cytidylyltransferase 4 228 4.4E-40 T 12-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 HW35_02335 d01408936494f9225490f4f387ab139c 517 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 198 4.2E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_02335 d01408936494f9225490f4f387ab139c 517 SUPERFAMILY SSF161098 14 198 2.49E-42 T 12-10-2018 IPR035906 MetI-like superfamily HW35_02335 d01408936494f9225490f4f387ab139c 517 Gene3D G3DSA:1.10.3720.10 10 207 2.9E-38 T 12-10-2018 IPR035906 MetI-like superfamily HW35_02335 d01408936494f9225490f4f387ab139c 517 Gene3D G3DSA:3.40.190.10 252 510 1.5E-104 T 12-10-2018 HW35_02335 d01408936494f9225490f4f387ab139c 517 Gene3D G3DSA:3.40.190.120 352 455 1.5E-104 T 12-10-2018 HW35_02335 d01408936494f9225490f4f387ab139c 517 SUPERFAMILY SSF53850 249 515 1.57E-75 T 12-10-2018 HW35_02335 d01408936494f9225490f4f387ab139c 517 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 249 511 3.3E-67 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 HW35_00515 6d670befc4300a2bc3c87af928d63b67 89 PIRSF PIRSF004669 1 89 1.0E-31 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HW35_00515 6d670befc4300a2bc3c87af928d63b67 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 8.8E-23 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HW35_00515 6d670befc4300a2bc3c87af928d63b67 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 8.8E-23 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HW35_00515 6d670befc4300a2bc3c87af928d63b67 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 8.8E-23 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HW35_00515 6d670befc4300a2bc3c87af928d63b67 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 9.3E-31 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HW35_00515 6d670befc4300a2bc3c87af928d63b67 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 5.4E-32 T 12-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 HW35_13455 f018abe13886e31cc69d6403a8433f58 418 SUPERFAMILY SSF47384 192 258 1.33E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_13455 f018abe13886e31cc69d6403a8433f58 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 305 408 1.0E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_13455 f018abe13886e31cc69d6403a8433f58 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 370 3.4E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_13455 f018abe13886e31cc69d6403a8433f58 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 408 3.4E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_13455 f018abe13886e31cc69d6403a8433f58 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 389 3.4E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_13455 f018abe13886e31cc69d6403a8433f58 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 356 3.4E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_13455 f018abe13886e31cc69d6403a8433f58 418 SUPERFAMILY SSF55874 253 411 6.55E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_13455 f018abe13886e31cc69d6403a8433f58 418 Gene3D G3DSA:3.30.565.10 263 417 3.5E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_13455 f018abe13886e31cc69d6403a8433f58 418 SMART SM00387 304 411 3.7E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_13455 f018abe13886e31cc69d6403a8433f58 418 SMART SM00388 199 262 3.2E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_13455 f018abe13886e31cc69d6403a8433f58 418 Gene3D G3DSA:1.10.287.130 184 261 1.9E-16 T 12-10-2018 HW35_13455 f018abe13886e31cc69d6403a8433f58 418 Pfam PF00512 His Kinase A (phospho-acceptor) domain 201 258 1.3E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_14805 b0d51afd3614e1615c1d2a129686c6ff 370 SMART SM00382 29 212 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_14805 b0d51afd3614e1615c1d2a129686c6ff 370 Pfam PF08402 TOBE domain 281 356 3.3E-8 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 HW35_14805 b0d51afd3614e1615c1d2a129686c6ff 370 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_14805 b0d51afd3614e1615c1d2a129686c6ff 370 Pfam PF00005 ABC transporter 21 162 3.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_14805 b0d51afd3614e1615c1d2a129686c6ff 370 Gene3D G3DSA:2.40.50.100 240 361 8.9E-37 T 12-10-2018 HW35_14805 b0d51afd3614e1615c1d2a129686c6ff 370 Gene3D G3DSA:3.40.50.300 1 239 3.9E-76 T 12-10-2018 HW35_14805 b0d51afd3614e1615c1d2a129686c6ff 370 SUPERFAMILY SSF50331 237 364 1.73E-29 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal HW35_14805 b0d51afd3614e1615c1d2a129686c6ff 370 SUPERFAMILY SSF52540 4 243 3.28E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14805 b0d51afd3614e1615c1d2a129686c6ff 370 Gene3D G3DSA:2.40.50.140 303 348 8.9E-37 T 12-10-2018 HW35_01615 0ca4df5f700df7fd743d9bd6f2f5face 409 SUPERFAMILY SSF103473 8 393 1.11E-60 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_01615 0ca4df5f700df7fd743d9bd6f2f5face 409 Pfam PF07690 Major Facilitator Superfamily 15 322 5.4E-39 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_01615 0ca4df5f700df7fd743d9bd6f2f5face 409 Gene3D G3DSA:1.20.1250.20 3 386 1.2E-50 T 12-10-2018 HW35_05055 faff242fdbee201177196ac0d0ea40d6 481 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 412 7.8E-111 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 HW35_05055 faff242fdbee201177196ac0d0ea40d6 481 SMART SM00316 36 114 3.4E-5 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_05055 faff242fdbee201177196ac0d0ea40d6 481 Pfam PF10150 Ribonuclease E/G family 117 379 5.4E-80 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 HW35_05055 faff242fdbee201177196ac0d0ea40d6 481 SUPERFAMILY SSF50249 38 115 2.57E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_05055 faff242fdbee201177196ac0d0ea40d6 481 Gene3D G3DSA:2.40.50.140 30 120 1.1E-24 T 12-10-2018 HW35_09250 7a78e5cdba1c1acf22b788b6324aa09c 189 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 168 15.516 T 12-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 HW35_09250 7a78e5cdba1c1acf22b788b6324aa09c 189 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 12 92 5.2E-34 T 12-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 HW35_09250 7a78e5cdba1c1acf22b788b6324aa09c 189 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 81 5.1E-11 T 12-10-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 HW35_09250 7a78e5cdba1c1acf22b788b6324aa09c 189 Gene3D G3DSA:1.10.10.1250 2 82 7.2E-33 T 12-10-2018 IPR038087 DNA-directed RNA polymerase subunit delta domain superfamily HW35_15820 2d24080c595f495bb5b5d40aac30da61 385 Pfam PF00155 Aminotransferase class I and II 30 375 7.9E-62 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HW35_15820 2d24080c595f495bb5b5d40aac30da61 385 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 228 241 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 HW35_15820 2d24080c595f495bb5b5d40aac30da61 385 SUPERFAMILY SSF53383 4 381 5.91E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_15820 2d24080c595f495bb5b5d40aac30da61 385 Gene3D G3DSA:3.90.1150.10 30 376 1.5E-126 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_15820 2d24080c595f495bb5b5d40aac30da61 385 Gene3D G3DSA:3.40.640.10 58 278 1.5E-126 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_11785 292c94349ce2384e13291769af0a0888 808 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 627 767 3.6E-25 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00397 Sirohaem Fe-binding site signature 674 692 4.9E-7 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00397 Sirohaem Fe-binding site signature 631 649 4.9E-7 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.7E-11 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 231 245 3.7E-11 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 3.7E-11 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 3.7E-11 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 279 3.1E-58 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_11785 292c94349ce2384e13291769af0a0888 808 Gene3D G3DSA:3.50.50.60 5 302 8.6E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_11785 292c94349ce2384e13291769af0a0888 808 Gene3D G3DSA:3.30.390.30 314 397 5.6E-10 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 8.3E-23 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 8.3E-23 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 8.3E-23 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 8.3E-23 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 8.3E-23 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 Gene3D G3DSA:3.90.480.20 493 629 1.1E-5 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 Gene3D G3DSA:3.50.50.60 113 237 8.6E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_11785 292c94349ce2384e13291769af0a0888 808 SUPERFAMILY SSF51905 141 304 1.3E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_11785 292c94349ce2384e13291769af0a0888 808 PIRSF PIRSF037149 1 806 0.0 T 12-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 HW35_11785 292c94349ce2384e13291769af0a0888 808 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 557 619 5.9E-13 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_11785 292c94349ce2384e13291769af0a0888 808 SUPERFAMILY SSF56014 628 785 5.76E-48 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 Gene3D G3DSA:3.30.413.10 630 802 7.9E-39 T 12-10-2018 HW35_11785 292c94349ce2384e13291769af0a0888 808 Pfam PF04324 BFD-like [2Fe-2S] binding domain 416 465 8.6E-15 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain HW35_11785 292c94349ce2384e13291769af0a0888 808 Pfam PF04324 BFD-like [2Fe-2S] binding domain 482 531 2.1E-13 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain HW35_11785 292c94349ce2384e13291769af0a0888 808 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 4 791 0.0 T 12-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 HW35_11785 292c94349ce2384e13291769af0a0888 808 SUPERFAMILY SSF55124 518 636 2.29E-23 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_11785 292c94349ce2384e13291769af0a0888 808 SUPERFAMILY SSF51905 2 187 3.98E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_11785 292c94349ce2384e13291769af0a0888 808 Gene3D G3DSA:1.10.10.1100 416 471 2.5E-11 T 12-10-2018 HW35_16365 11456fc2810190b762b6114c53876749 382 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 370 39.619 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 HW35_16365 11456fc2810190b762b6114c53876749 382 Gene3D G3DSA:3.40.50.1440 5 220 2.0E-84 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 HW35_16365 11456fc2810190b762b6114c53876749 382 SMART SM00865 207 324 2.8E-55 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 HW35_16365 11456fc2810190b762b6114c53876749 382 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 HW35_16365 11456fc2810190b762b6114c53876749 382 SMART SM00864 13 205 5.6E-117 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HW35_16365 11456fc2810190b762b6114c53876749 382 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 HW35_16365 11456fc2810190b762b6114c53876749 382 Gene3D G3DSA:3.30.1330.20 221 329 9.3E-43 T 12-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 HW35_16365 11456fc2810190b762b6114c53876749 382 SUPERFAMILY SSF55307 204 319 8.24E-45 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 HW35_16365 11456fc2810190b762b6114c53876749 382 Pfam PF12327 FtsZ family, C-terminal domain 222 315 2.2E-33 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal HW35_16365 11456fc2810190b762b6114c53876749 382 PRINTS PR00423 Cell division protein FtsZ signature 126 147 3.9E-53 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HW35_16365 11456fc2810190b762b6114c53876749 382 PRINTS PR00423 Cell division protein FtsZ signature 189 211 3.9E-53 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HW35_16365 11456fc2810190b762b6114c53876749 382 PRINTS PR00423 Cell division protein FtsZ signature 212 233 3.9E-53 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HW35_16365 11456fc2810190b762b6114c53876749 382 PRINTS PR00423 Cell division protein FtsZ signature 98 118 3.9E-53 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HW35_16365 11456fc2810190b762b6114c53876749 382 SUPERFAMILY SSF52490 12 208 2.88E-72 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 HW35_16365 11456fc2810190b762b6114c53876749 382 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 6 325 1.4E-140 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 HW35_16365 11456fc2810190b762b6114c53876749 382 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 1.5E-45 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HW35_12445 1a45bb37d05c1c127a95bbff9289b4cb 369 Pfam PF01266 FAD dependent oxidoreductase 6 348 7.9E-82 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HW35_12445 1a45bb37d05c1c127a95bbff9289b4cb 369 Gene3D G3DSA:3.30.9.10 92 308 9.2E-117 T 12-10-2018 HW35_12445 1a45bb37d05c1c127a95bbff9289b4cb 369 Gene3D G3DSA:3.50.50.60 6 349 9.2E-117 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_12445 1a45bb37d05c1c127a95bbff9289b4cb 369 SUPERFAMILY SSF51905 5 357 7.77E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_12445 1a45bb37d05c1c127a95bbff9289b4cb 369 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 8 352 5.2E-107 T 12-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 HW35_12445 1a45bb37d05c1c127a95bbff9289b4cb 369 SUPERFAMILY SSF54373 221 308 5.36E-19 T 12-10-2018 HW35_06355 90edc21469cb0aa2db40de0ea0544108 86 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 76 1.9E-33 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor HW35_06355 90edc21469cb0aa2db40de0ea0544108 86 SMART SM01234 2 69 3.8E-47 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor HW35_06355 90edc21469cb0aa2db40de0ea0544108 86 Pfam PF01809 Haemolytic domain 3 69 1.2E-31 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor HW35_06355 90edc21469cb0aa2db40de0ea0544108 86 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 2 70 25.801 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor HW35_06355 90edc21469cb0aa2db40de0ea0544108 86 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 69 2.0E-21 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor HW35_07940 8faf4984a604520032e12965cd8f4814 116 SUPERFAMILY SSF103481 17 112 3.14E-10 T 12-10-2018 HW35_07940 8faf4984a604520032e12965cd8f4814 116 Pfam PF00892 EamA-like transporter family 15 111 1.0E-8 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_07650 3510c6e9ebe7885d92ded6ffe9b32984 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HW35_07650 3510c6e9ebe7885d92ded6ffe9b32984 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 175 1.0E-65 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HW35_07650 3510c6e9ebe7885d92ded6ffe9b32984 195 SUPERFAMILY SSF54211 3 87 6.32E-33 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_07650 3510c6e9ebe7885d92ded6ffe9b32984 195 SUPERFAMILY SSF54211 88 180 6.37E-36 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_07650 3510c6e9ebe7885d92ded6ffe9b32984 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 157 169 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HW35_07650 3510c6e9ebe7885d92ded6ffe9b32984 195 Gene3D G3DSA:3.30.230.40 91 195 2.3E-40 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 HW35_07650 3510c6e9ebe7885d92ded6ffe9b32984 195 Gene3D G3DSA:3.30.230.40 1 90 3.2E-39 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 HW35_07650 3510c6e9ebe7885d92ded6ffe9b32984 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 195 43.178 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HW35_10810 6a3cc66fb830ccd04ce28da32023bc0c 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 8.2E-57 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10810 6a3cc66fb830ccd04ce28da32023bc0c 146 SUPERFAMILY SSF52080 4 143 1.7E-50 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily HW35_10810 6a3cc66fb830ccd04ce28da32023bc0c 146 Gene3D G3DSA:3.100.10.10 66 146 2.5E-27 T 12-10-2018 HW35_10810 6a3cc66fb830ccd04ce28da32023bc0c 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 12-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10810 6a3cc66fb830ccd04ce28da32023bc0c 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 23.138 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 HW35_10810 6a3cc66fb830ccd04ce28da32023bc0c 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 144 4.3E-38 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P HW35_05120 4521c07daa9b8a86bc68ae44bf71853d 179 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 28 4.6E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_05120 4521c07daa9b8a86bc68ae44bf71853d 179 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 28 1.4E-4 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_05120 4521c07daa9b8a86bc68ae44bf71853d 179 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_02770 d078388a42eee2c444a96864b4195fd6 139 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 2 131 1.5E-64 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 HW35_02770 d078388a42eee2c444a96864b4195fd6 139 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 2 123 37.269 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 HW35_02770 d078388a42eee2c444a96864b4195fd6 139 SUPERFAMILY SSF51316 2 138 2.46E-60 T 12-10-2018 IPR011057 Mss4-like superfamily HW35_02770 d078388a42eee2c444a96864b4195fd6 139 Gene3D G3DSA:2.170.150.20 1 139 1.9E-60 T 12-10-2018 HW35_02770 d078388a42eee2c444a96864b4195fd6 139 Pfam PF01641 SelR domain 4 122 2.6E-50 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 HW35_13900 7b210b8ea85f77fe16a6a30c321cbf9b 342 Gene3D G3DSA:3.80.30.30 116 342 1.6E-88 T 12-10-2018 HW35_13900 7b210b8ea85f77fe16a6a30c321cbf9b 342 Gene3D G3DSA:3.40.50.12110 3 115 2.4E-46 T 12-10-2018 HW35_13900 7b210b8ea85f77fe16a6a30c321cbf9b 342 SUPERFAMILY SSF102114 85 261 3.66E-5 T 12-10-2018 HW35_13900 7b210b8ea85f77fe16a6a30c321cbf9b 342 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 5 342 4.8E-153 T 12-10-2018 IPR023897 Spore photoproduct lyase GO:0003913 HW35_07220 88f42ef673860b8a895d73298b799700 503 Pfam PF01145 SPFH domain / Band 7 family 29 219 3.8E-25 T 12-10-2018 IPR001107 Band 7 domain HW35_07220 88f42ef673860b8a895d73298b799700 503 SUPERFAMILY SSF117892 67 209 2.35E-34 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily HW35_07220 88f42ef673860b8a895d73298b799700 503 Gene3D G3DSA:3.30.479.30 76 192 2.1E-38 T 12-10-2018 HW35_07220 88f42ef673860b8a895d73298b799700 503 SMART SM00244 118 300 3.4E-13 T 12-10-2018 IPR001107 Band 7 domain HW35_07220 88f42ef673860b8a895d73298b799700 503 Pfam PF15975 Flotillin 367 461 5.6E-14 T 12-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 HW35_10765 aaa52040a989536e2a67fe32df93b3bc 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.8E-58 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 HW35_10765 aaa52040a989536e2a67fe32df93b3bc 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.779 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HW35_10765 aaa52040a989536e2a67fe32df93b3bc 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 4.8E-55 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HW35_10765 aaa52040a989536e2a67fe32df93b3bc 122 SUPERFAMILY SSF50193 1 122 1.06E-50 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 HW35_10765 aaa52040a989536e2a67fe32df93b3bc 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10765 aaa52040a989536e2a67fe32df93b3bc 122 Gene3D G3DSA:2.40.150.20 1 122 3.5E-54 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 HW35_10765 aaa52040a989536e2a67fe32df93b3bc 122 SMART SM01374 1 122 4.8E-87 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HW35_08785 d7143359ed85d40689b36889aa3067ec 470 Pfam PF01943 Polysaccharide biosynthesis protein 4 273 3.8E-27 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HW35_08785 d7143359ed85d40689b36889aa3067ec 470 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 329 442 1.5E-7 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HW35_11200 bfe992630f081cdfd8bc8f24d07434b8 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 301 315 1.2E-15 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HW35_11200 bfe992630f081cdfd8bc8f24d07434b8 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 388 399 1.2E-15 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HW35_11200 bfe992630f081cdfd8bc8f24d07434b8 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 427 1.2E-15 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HW35_11200 bfe992630f081cdfd8bc8f24d07434b8 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 435 447 1.2E-15 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HW35_11200 bfe992630f081cdfd8bc8f24d07434b8 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 367 375 1.2E-15 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HW35_11200 bfe992630f081cdfd8bc8f24d07434b8 482 Gene3D G3DSA:3.20.20.80 1 473 3.1E-153 T 12-10-2018 HW35_11200 bfe992630f081cdfd8bc8f24d07434b8 482 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 367 375 - T 12-10-2018 IPR018120 Glycoside hydrolase family 1, active site HW35_11200 bfe992630f081cdfd8bc8f24d07434b8 482 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 6 20 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site HW35_11200 bfe992630f081cdfd8bc8f24d07434b8 482 Pfam PF00232 Glycosyl hydrolase family 1 3 470 7.4E-135 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HW35_11200 bfe992630f081cdfd8bc8f24d07434b8 482 SUPERFAMILY SSF51445 4 471 3.68E-152 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 PRINTS PR00988 Uridine kinase signature 4 21 3.9E-37 T 12-10-2018 HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 PRINTS PR00988 Uridine kinase signature 171 184 3.9E-37 T 12-10-2018 HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 PRINTS PR00988 Uridine kinase signature 79 94 3.9E-37 T 12-10-2018 HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 PRINTS PR00988 Uridine kinase signature 135 145 3.9E-37 T 12-10-2018 HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 PRINTS PR00988 Uridine kinase signature 149 160 3.9E-37 T 12-10-2018 HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 PRINTS PR00988 Uridine kinase signature 34 45 3.9E-37 T 12-10-2018 HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 Gene3D G3DSA:3.40.50.300 2 209 6.6E-66 T 12-10-2018 HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 Hamap MF_00551 Uridine kinase [udk]. 1 205 42.505 T 12-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 6 191 8.7E-43 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 TIGRFAM TIGR00235 udk: uridine kinase 3 205 3.9E-93 T 12-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 HW35_04735 e235ea9ff61c3518171eb4250e9978a8 210 SUPERFAMILY SSF52540 2 196 5.16E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 225 231 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 Gene3D G3DSA:3.40.50.150 8 294 1.3E-71 T 12-10-2018 HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 12 294 2.5E-52 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 SUPERFAMILY SSF53335 6 333 2.04E-58 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 Gene3D G3DSA:1.10.1020.10 66 189 1.3E-71 T 12-10-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 12 28 2.0E-14 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 59 72 2.0E-14 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 35 49 2.0E-14 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 222 234 2.0E-14 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 TIGRFAM TIGR00571 dam: DNA adenine methylase 7 332 4.6E-74 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 HW35_01480 561d20be01c19a217707338bbf8b2fa7 334 PIRSF PIRSF000398 5 334 5.8E-62 T 12-10-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 HW35_12650 1d55477434bbc59ef5ce3bf188318c66 65 Pfam PF13783 Domain of unknown function (DUF4177) 2 62 2.0E-18 T 12-10-2018 IPR025234 Protein of unknown function DUF4177 HW35_04685 4b45e57566518a2354c5991301cb0b22 313 Gene3D G3DSA:2.130.10.10 238 312 1.4E-5 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 HW35_04685 4b45e57566518a2354c5991301cb0b22 313 Gene3D G3DSA:2.130.10.10 10 237 3.5E-11 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 HW35_04685 4b45e57566518a2354c5991301cb0b22 313 SUPERFAMILY SSF50939 94 304 5.49E-18 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 HW35_04570 2c608a8bc23226bd3636bce9d39e9772 398 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 102 378 9.9E-76 T 12-10-2018 IPR010897 Sporulation stage II, protein P HW35_04570 2c608a8bc23226bd3636bce9d39e9772 398 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 180 382 2.3E-75 T 12-10-2018 IPR010897 Sporulation stage II, protein P HW35_04570 2c608a8bc23226bd3636bce9d39e9772 398 SUPERFAMILY SSF53187 259 382 3.77E-10 T 12-10-2018 HW35_02575 5b4cb5d4ee732c81d6a43eb9d5e02507 424 ProSitePatterns PS00216 Sugar transport proteins signature 1. 88 104 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HW35_02575 5b4cb5d4ee732c81d6a43eb9d5e02507 424 PRINTS PR01035 Tetracycline resistance protein signature 44 60 1.6E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_02575 5b4cb5d4ee732c81d6a43eb9d5e02507 424 PRINTS PR01035 Tetracycline resistance protein signature 165 187 1.6E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_02575 5b4cb5d4ee732c81d6a43eb9d5e02507 424 PRINTS PR01035 Tetracycline resistance protein signature 193 213 1.6E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_02575 5b4cb5d4ee732c81d6a43eb9d5e02507 424 PRINTS PR01035 Tetracycline resistance protein signature 334 354 1.6E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_02575 5b4cb5d4ee732c81d6a43eb9d5e02507 424 Pfam PF07690 Major Facilitator Superfamily 44 385 1.4E-49 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_02575 5b4cb5d4ee732c81d6a43eb9d5e02507 424 SUPERFAMILY SSF103473 26 421 2.22E-65 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_02575 5b4cb5d4ee732c81d6a43eb9d5e02507 424 Gene3D G3DSA:1.20.1250.20 31 222 1.6E-35 T 12-10-2018 HW35_02575 5b4cb5d4ee732c81d6a43eb9d5e02507 424 Gene3D G3DSA:1.20.1250.20 231 423 3.0E-23 T 12-10-2018 HW35_03945 f4265e204602bc1b03052874e8454533 562 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 554 6.6E-200 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HW35_03945 f4265e204602bc1b03052874e8454533 562 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 509 9.2E-18 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal HW35_03945 f4265e204602bc1b03052874e8454533 562 PIRSF PIRSF003128 1 558 1.7E-191 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HW35_03945 f4265e204602bc1b03052874e8454533 562 Gene3D G3DSA:3.40.50.300 1 258 5.0E-54 T 12-10-2018 HW35_03945 f4265e204602bc1b03052874e8454533 562 Gene3D G3DSA:3.40.50.300 259 555 3.3E-58 T 12-10-2018 HW35_03945 f4265e204602bc1b03052874e8454533 562 SUPERFAMILY SSF52540 2 518 9.47E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07240 8f4ead15c8123c606a00c5ff98ad67ea 232 SUPERFAMILY SSF161098 26 213 9.81E-47 T 12-10-2018 IPR035906 MetI-like superfamily HW35_07240 8f4ead15c8123c606a00c5ff98ad67ea 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 26 122 1.6E-31 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 HW35_07240 8f4ead15c8123c606a00c5ff98ad67ea 232 Gene3D G3DSA:1.10.3720.10 19 230 6.8E-54 T 12-10-2018 IPR035906 MetI-like superfamily HW35_07240 8f4ead15c8123c606a00c5ff98ad67ea 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 228 2.5E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_11250 8c77f54f3fd5269a4db0e38d82ba5db2 472 Pfam PF02378 Phosphotransferase system, EIIC 24 282 1.6E-22 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HW35_11250 8c77f54f3fd5269a4db0e38d82ba5db2 472 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 14 351 1.7E-187 T 12-10-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197 HW35_11250 8c77f54f3fd5269a4db0e38d82ba5db2 472 SUPERFAMILY SSF52794 383 471 1.96E-27 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_11250 8c77f54f3fd5269a4db0e38d82ba5db2 472 Gene3D G3DSA:3.40.50.2300 372 472 5.6E-39 T 12-10-2018 HW35_11250 8c77f54f3fd5269a4db0e38d82ba5db2 472 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 385 468 2.5E-14 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HW35_00030 5224150b07802a34eb2e84051f8ae409 260 Pfam PF03741 Integral membrane protein TerC family 15 205 6.0E-50 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 HW35_00030 5224150b07802a34eb2e84051f8ae409 260 SUPERFAMILY SSF103473 10 241 4.45E-5 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_00030 5224150b07802a34eb2e84051f8ae409 260 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 246 2.7E-89 T 12-10-2018 IPR022493 Integral membrane YkoY HW35_08905 9530b5d745cf2197396daf650b93dfaa 375 Pfam PF06725 3D domain 316 375 1.5E-19 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 HW35_08905 9530b5d745cf2197396daf650b93dfaa 375 Gene3D G3DSA:2.40.40.10 166 353 7.5E-6 T 12-10-2018 IPR036908 RlpA-like domain superfamily HW35_08905 9530b5d745cf2197396daf650b93dfaa 375 SUPERFAMILY SSF50685 315 355 4.88E-8 T 12-10-2018 IPR036908 RlpA-like domain superfamily HW35_13740 6cfec5caebc01b92200db55c8cbf414f 356 TIGRFAM TIGR00378 cax: calcium/proton exchanger 11 354 1.7E-149 T 12-10-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 HW35_13740 6cfec5caebc01b92200db55c8cbf414f 356 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 2 353 3.6E-121 T 12-10-2018 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 HW35_13740 6cfec5caebc01b92200db55c8cbf414f 356 Pfam PF01699 Sodium/calcium exchanger protein 28 179 2.9E-16 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 HW35_13740 6cfec5caebc01b92200db55c8cbf414f 356 Pfam PF01699 Sodium/calcium exchanger protein 211 348 1.0E-19 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 HW35_13740 6cfec5caebc01b92200db55c8cbf414f 356 Gene3D G3DSA:1.20.1420.30 58 346 1.8E-24 T 12-10-2018 HW35_13740 6cfec5caebc01b92200db55c8cbf414f 356 Gene3D G3DSA:1.20.58.1130 41 243 1.8E-24 T 12-10-2018 HW35_11350 d1bd25db6bd2a08a730cd44b623c0a9b 165 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 HW35_11350 d1bd25db6bd2a08a730cd44b623c0a9b 165 Gene3D G3DSA:3.30.160.70 3 73 7.2E-14 T 12-10-2018 HW35_11350 d1bd25db6bd2a08a730cd44b623c0a9b 165 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 159 37.959 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 HW35_11350 d1bd25db6bd2a08a730cd44b623c0a9b 165 Gene3D G3DSA:1.10.10.10 77 161 3.8E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_11350 d1bd25db6bd2a08a730cd44b623c0a9b 165 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 3 75 5.7E-11 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 HW35_11350 d1bd25db6bd2a08a730cd44b623c0a9b 165 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 159 1.0E-31 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 HW35_11350 d1bd25db6bd2a08a730cd44b623c0a9b 165 SUPERFAMILY SSF53155 3 83 2.35E-16 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 HW35_11350 d1bd25db6bd2a08a730cd44b623c0a9b 165 SUPERFAMILY SSF46767 77 160 7.85E-31 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 HW35_11350 d1bd25db6bd2a08a730cd44b623c0a9b 165 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 158 5.9E-35 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 HW35_09490 9d609e175a7db18faa5b85d56dca2942 265 Pfam PF12679 ABC-2 family transporter protein 48 263 2.6E-13 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 HW35_06680 03a65953ca925e6fd048cf6254ab69a0 398 Gene3D G3DSA:1.20.1250.20 4 385 9.3E-56 T 12-10-2018 HW35_06680 03a65953ca925e6fd048cf6254ab69a0 398 Pfam PF07690 Major Facilitator Superfamily 15 347 8.7E-45 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_06680 03a65953ca925e6fd048cf6254ab69a0 398 ProSitePatterns PS00217 Sugar transport proteins signature 2. 107 132 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HW35_06680 03a65953ca925e6fd048cf6254ab69a0 398 ProSitePatterns PS00217 Sugar transport proteins signature 2. 304 329 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HW35_06680 03a65953ca925e6fd048cf6254ab69a0 398 SUPERFAMILY SSF103473 1 393 2.88E-65 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_12290 43b062e1845d440c661fd2bbfca99eb7 460 PRINTS PR00173 Glutamate-aspartate symporter signature 397 417 5.0E-11 T 12-10-2018 HW35_12290 43b062e1845d440c661fd2bbfca99eb7 460 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 5.0E-11 T 12-10-2018 HW35_12290 43b062e1845d440c661fd2bbfca99eb7 460 PRINTS PR00173 Glutamate-aspartate symporter signature 182 204 5.0E-11 T 12-10-2018 HW35_12290 43b062e1845d440c661fd2bbfca99eb7 460 PRINTS PR00173 Glutamate-aspartate symporter signature 370 389 5.0E-11 T 12-10-2018 HW35_12290 43b062e1845d440c661fd2bbfca99eb7 460 Gene3D G3DSA:1.10.3860.10 20 458 1.2E-99 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 HW35_12290 43b062e1845d440c661fd2bbfca99eb7 460 Pfam PF00375 Sodium:dicarboxylate symporter family 32 442 1.2E-98 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 HW35_12290 43b062e1845d440c661fd2bbfca99eb7 460 SUPERFAMILY SSF118215 30 442 3.01E-90 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 Pfam PF01068 ATP dependent DNA ligase domain 14 207 1.6E-33 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 Gene3D G3DSA:2.40.50.140 214 310 7.4E-8 T 12-10-2018 HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 21 29 - T 12-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 323 563 1.1E-86 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 4 309 2.5E-76 T 12-10-2018 IPR014146 DNA ligase D, ligase domain HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 SUPERFAMILY SSF56091 2 207 2.64E-35 T 12-10-2018 HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 SUPERFAMILY SSF50249 224 314 2.74E-8 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 Gene3D G3DSA:3.90.920.30 331 603 1.0E-81 T 12-10-2018 HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 13 591 1.7E-183 T 12-10-2018 IPR014143 DNA ligase D HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 Gene3D G3DSA:3.30.470.30 1 207 6.4E-38 T 12-10-2018 HW35_02605 caef9852a8c96dde106ba1f1221e71df 609 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 183 207 - T 12-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 HW35_17705 a9fa9a0977a3516c06c436ef3e46d6c6 351 Gene3D G3DSA:3.40.50.720 5 331 8.8E-101 T 12-10-2018 HW35_17705 a9fa9a0977a3516c06c436ef3e46d6c6 351 Gene3D G3DSA:3.30.360.10 162 324 8.8E-101 T 12-10-2018 HW35_17705 a9fa9a0977a3516c06c436ef3e46d6c6 351 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 9 82 6.7E-5 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_17705 a9fa9a0977a3516c06c436ef3e46d6c6 351 PIRSF PIRSF036497 1 348 6.1E-103 T 12-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HW35_17705 a9fa9a0977a3516c06c436ef3e46d6c6 351 Pfam PF00742 Homoserine dehydrogenase 168 340 1.8E-56 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HW35_17705 a9fa9a0977a3516c06c436ef3e46d6c6 351 SUPERFAMILY SSF55347 168 327 1.57E-50 T 12-10-2018 HW35_17705 a9fa9a0977a3516c06c436ef3e46d6c6 351 SUPERFAMILY SSF51735 4 226 3.34E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_17705 a9fa9a0977a3516c06c436ef3e46d6c6 351 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 208 230 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HW35_09560 0c54330813c27449d68d9721f3495b1c 574 SUPERFAMILY SSF52540 323 569 1.09E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09560 0c54330813c27449d68d9721f3495b1c 574 Pfam PF00005 ABC transporter 349 498 7.7E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_09560 0c54330813c27449d68d9721f3495b1c 574 SMART SM00382 358 544 8.9E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_09560 0c54330813c27449d68d9721f3495b1c 574 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_09560 0c54330813c27449d68d9721f3495b1c 574 Gene3D G3DSA:3.40.50.300 321 573 3.1E-88 T 12-10-2018 HW35_09560 0c54330813c27449d68d9721f3495b1c 574 Pfam PF00664 ABC transporter transmembrane region 17 285 9.6E-43 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 HW35_09560 0c54330813c27449d68d9721f3495b1c 574 SUPERFAMILY SSF90123 3 313 1.96E-72 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_09560 0c54330813c27449d68d9721f3495b1c 574 Gene3D G3DSA:1.20.1560.10 1 313 1.8E-90 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 PRINTS PR00139 Asparaginase/glutaminase family signature 254 272 6.6E-19 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 PRINTS PR00139 Asparaginase/glutaminase family signature 81 99 6.6E-19 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 6.6E-19 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 PIRSF PIRSF001220 1 318 1.9E-91 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 SUPERFAMILY SSF53774 1 314 7.98E-89 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 PIRSF PIRSF500176 1 317 2.8E-88 T 12-10-2018 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 12-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 SMART SM00870 3 317 7.7E-110 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 Gene3D G3DSA:3.40.50.40 210 317 1.3E-25 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 Gene3D G3DSA:3.40.50.1170 1 209 2.9E-61 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 Pfam PF00710 Asparaginase, N-terminal 3 194 1.0E-51 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 HW35_03460 64064ec26fc943a8e0c49549e5253c8d 318 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 82 92 - T 12-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 HW35_07245 22985ec30f28f545f9c8b8e6d1ab9fd8 274 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 54 270 2.8E-67 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_07245 22985ec30f28f545f9c8b8e6d1ab9fd8 274 SMART SM00079 52 270 0.0087 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HW35_07245 22985ec30f28f545f9c8b8e6d1ab9fd8 274 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 75 88 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site HW35_07245 22985ec30f28f545f9c8b8e6d1ab9fd8 274 Gene3D G3DSA:3.40.190.10 135 232 2.3E-75 T 12-10-2018 HW35_07245 22985ec30f28f545f9c8b8e6d1ab9fd8 274 SMART SM00062 52 271 2.1E-83 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_07245 22985ec30f28f545f9c8b8e6d1ab9fd8 274 Gene3D G3DSA:3.40.190.10 51 263 2.3E-75 T 12-10-2018 HW35_07245 22985ec30f28f545f9c8b8e6d1ab9fd8 274 SUPERFAMILY SSF53850 4 271 3.19E-73 T 12-10-2018 HW35_12105 34e07f7b3135719063027be642e7d2bc 352 Pfam PF13407 Periplasmic binding protein domain 45 317 1.2E-65 T 12-10-2018 IPR025997 Periplasmic binding protein HW35_12105 34e07f7b3135719063027be642e7d2bc 352 Gene3D G3DSA:3.40.50.2300 43 319 4.2E-111 T 12-10-2018 HW35_12105 34e07f7b3135719063027be642e7d2bc 352 SUPERFAMILY SSF53822 43 345 1.03E-80 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_12105 34e07f7b3135719063027be642e7d2bc 352 Gene3D G3DSA:3.40.50.2300 147 296 4.2E-111 T 12-10-2018 HW35_05985 73496adb9b946b4ddaba1795696a0639 213 SUPERFAMILY SSF53335 29 209 1.41E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_05985 73496adb9b946b4ddaba1795696a0639 213 Gene3D G3DSA:3.40.50.150 1 211 5.0E-76 T 12-10-2018 HW35_05985 73496adb9b946b4ddaba1795696a0639 213 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 30.657 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 HW35_05985 73496adb9b946b4ddaba1795696a0639 213 Pfam PF02390 Putative methyltransferase 39 207 9.7E-50 T 12-10-2018 HW35_05985 73496adb9b946b4ddaba1795696a0639 213 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 28 210 1.2E-61 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 HW35_16585 7d702141bb7658f2fa4cc0056a1719c1 214 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HW35_16585 7d702141bb7658f2fa4cc0056a1719c1 214 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 2.2E-92 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HW35_16585 7d702141bb7658f2fa4cc0056a1719c1 214 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 3.6E-98 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HW35_16585 7d702141bb7658f2fa4cc0056a1719c1 214 PIRSF PIRSF001461 1 214 8.6E-102 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HW35_16585 7d702141bb7658f2fa4cc0056a1719c1 214 SUPERFAMILY SSF51366 1 213 1.68E-81 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HW35_16585 7d702141bb7658f2fa4cc0056a1719c1 214 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HW35_16585 7d702141bb7658f2fa4cc0056a1719c1 214 Gene3D G3DSA:3.20.20.70 1 214 6.8E-96 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 SUPERFAMILY SSF52540 21 253 5.75E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 331 2.0E-33 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 328 1.7E-150 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 236 1.6E-119 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 Gene3D G3DSA:3.40.50.300 21 182 6.7E-41 T 12-10-2018 HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 5.1E-35 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 333 176.308 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 Gene3D G3DSA:1.10.10.10 258 333 4.7E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 SMART SM00382 52 180 1.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 Gene3D G3DSA:1.10.8.60 183 257 3.4E-32 T 12-10-2018 HW35_04965 ed4f303cf2db0c1d8bcbd0ad1ae05301 333 SUPERFAMILY SSF46785 257 331 7.62E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_08625 9f4d677deb1e4345db7029a3722a269b 242 SMART SM00345 15 74 6.7E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_08625 9f4d677deb1e4345db7029a3722a269b 242 Gene3D G3DSA:1.20.120.530 82 236 2.7E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal HW35_08625 9f4d677deb1e4345db7029a3722a269b 242 Gene3D G3DSA:1.10.10.10 1 74 5.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_08625 9f4d677deb1e4345db7029a3722a269b 242 SUPERFAMILY SSF46785 5 78 5.71E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_08625 9f4d677deb1e4345db7029a3722a269b 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.4E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_08625 9f4d677deb1e4345db7029a3722a269b 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_08625 9f4d677deb1e4345db7029a3722a269b 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_08625 9f4d677deb1e4345db7029a3722a269b 242 Pfam PF07729 FCD domain 99 225 4.4E-23 T 12-10-2018 IPR011711 GntR, C-terminal HW35_08625 9f4d677deb1e4345db7029a3722a269b 242 SUPERFAMILY SSF48008 95 233 1.07E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal HW35_08625 9f4d677deb1e4345db7029a3722a269b 242 SMART SM00895 99 226 3.1E-20 T 12-10-2018 IPR011711 GntR, C-terminal HW35_00800 05a952dd4d80f0559459e322459e4688 421 Gene3D G3DSA:3.40.50.1100 58 157 1.4E-117 T 12-10-2018 HW35_00800 05a952dd4d80f0559459e322459e4688 421 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 328 419 3.7E-26 T 12-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 HW35_00800 05a952dd4d80f0559459e322459e4688 421 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 315 2.6E-76 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HW35_00800 05a952dd4d80f0559459e322459e4688 421 SUPERFAMILY SSF55021 338 415 5.04E-11 T 12-10-2018 HW35_00800 05a952dd4d80f0559459e322459e4688 421 SUPERFAMILY SSF53686 12 365 4.98E-100 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HW35_00800 05a952dd4d80f0559459e322459e4688 421 Gene3D G3DSA:3.40.1020.10 327 421 9.2E-10 T 12-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 HW35_00800 05a952dd4d80f0559459e322459e4688 421 TIGRFAM TIGR02079 THD1: threonine dehydratase 14 421 6.8E-195 T 12-10-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 HW35_00800 05a952dd4d80f0559459e322459e4688 421 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 HW35_00800 05a952dd4d80f0559459e322459e4688 421 Gene3D G3DSA:3.40.50.1100 23 326 1.4E-117 T 12-10-2018 HW35_13050 0a1b4258defd004f6a627bdca47967de 69 Pfam PF01361 Tautomerase enzyme 2 58 4.8E-14 T 12-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 HW35_13050 0a1b4258defd004f6a627bdca47967de 69 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 57 1.0E-17 T 12-10-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 HW35_13050 0a1b4258defd004f6a627bdca47967de 69 SUPERFAMILY SSF55331 2 58 1.05E-15 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily HW35_13050 0a1b4258defd004f6a627bdca47967de 69 Gene3D G3DSA:3.30.429.10 1 65 6.8E-21 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily HW35_14665 80906245edc96a4d26814d9087c7c5ba 223 SMART SM01133 4 216 2.9E-109 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 HW35_14665 80906245edc96a4d26814d9087c7c5ba 223 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 3 218 38.174 T 12-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 HW35_14665 80906245edc96a4d26814d9087c7c5ba 223 Pfam PF01791 DeoC/LacD family aldolase 8 215 2.8E-22 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 HW35_14665 80906245edc96a4d26814d9087c7c5ba 223 SUPERFAMILY SSF51569 3 216 4.19E-87 T 12-10-2018 HW35_14665 80906245edc96a4d26814d9087c7c5ba 223 PIRSF PIRSF001357 1 222 2.0E-81 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 HW35_14665 80906245edc96a4d26814d9087c7c5ba 223 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 5 214 2.0E-95 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 HW35_14665 80906245edc96a4d26814d9087c7c5ba 223 Gene3D G3DSA:3.20.20.70 1 221 4.5E-101 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_16125 51cfee6780fe0bb55a5899b8ed71bd66 120 SUPERFAMILY SSF160755 1 114 2.09E-41 T 12-10-2018 IPR036491 YugN-like superfamily HW35_16125 51cfee6780fe0bb55a5899b8ed71bd66 120 Gene3D G3DSA:3.30.310.100 1 120 2.3E-47 T 12-10-2018 IPR036491 YugN-like superfamily HW35_16125 51cfee6780fe0bb55a5899b8ed71bd66 120 Pfam PF08868 YugN-like family 6 105 4.2E-14 T 12-10-2018 IPR014967 Uncharacterised protein family, YugN-like HW35_04025 2ab9bc702642ff9145cba04b2131a509 98 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 2 96 4.4E-35 T 12-10-2018 IPR014211 Stage III sporulation protein AD HW35_04025 2ab9bc702642ff9145cba04b2131a509 98 Pfam PF06686 Stage III sporulation protein AC/AD protein family 40 94 2.9E-19 T 12-10-2018 IPR025664 Stage III sporulation protein AC/AD family HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 PIRSF PIRSF037215 1 410 5.6E-200 T 12-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 Pfam PF01546 Peptidase family M20/M25/M40 141 401 3.3E-11 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 Gene3D G3DSA:3.40.630.10 5 402 4.2E-189 T 12-10-2018 HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 410 3.3E-210 T 12-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 SUPERFAMILY SSF53187 3 404 3.83E-83 T 12-10-2018 HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 Hamap MF_00550 Peptidase T [pepT]. 2 406 61.0 T 12-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 SUPERFAMILY SSF55031 211 322 6.28E-42 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 Gene3D G3DSA:3.30.70.360 211 321 4.2E-189 T 12-10-2018 HW35_09570 5115d22717e3a04f7d83432ccfe182be 410 Pfam PF07687 Peptidase dimerisation domain 209 308 1.6E-13 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain HW35_03000 0840ea64e53e47755472192a714f1a04 275 SMART SM00450 5 131 1.7E-25 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_03000 0840ea64e53e47755472192a714f1a04 275 SMART SM00450 154 272 1.4E-17 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_03000 0840ea64e53e47755472192a714f1a04 275 Pfam PF00581 Rhodanese-like domain 157 267 1.5E-14 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_03000 0840ea64e53e47755472192a714f1a04 275 Pfam PF00581 Rhodanese-like domain 7 127 1.9E-22 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_03000 0840ea64e53e47755472192a714f1a04 275 Gene3D G3DSA:3.40.250.10 160 275 1.7E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_03000 0840ea64e53e47755472192a714f1a04 275 ProSitePatterns PS00380 Rhodanese signature 1. 38 49 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 HW35_03000 0840ea64e53e47755472192a714f1a04 275 Gene3D G3DSA:3.40.250.10 1 148 4.1E-49 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_03000 0840ea64e53e47755472192a714f1a04 275 SUPERFAMILY SSF52821 151 268 1.96E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_03000 0840ea64e53e47755472192a714f1a04 275 SUPERFAMILY SSF52821 3 150 9.17E-42 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_08895 9077d0cc0e53930f1bde49b4a1a85914 976 Pfam PF12419 SNF2 Helicase protein 303 435 2.2E-37 T 12-10-2018 IPR022138 Helicase SWF/SNF-related HW35_08895 9077d0cc0e53930f1bde49b4a1a85914 976 Gene3D G3DSA:3.40.50.10810 455 720 3.9E-69 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily HW35_08895 9077d0cc0e53930f1bde49b4a1a85914 976 SMART SM00490 837 920 7.0E-25 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_08895 9077d0cc0e53930f1bde49b4a1a85914 976 SUPERFAMILY SSF52540 463 721 3.15E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_08895 9077d0cc0e53930f1bde49b4a1a85914 976 Pfam PF00271 Helicase conserved C-terminal domain 808 920 9.4E-22 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_08895 9077d0cc0e53930f1bde49b4a1a85914 976 SUPERFAMILY SSF52540 726 973 1.95E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_08895 9077d0cc0e53930f1bde49b4a1a85914 976 Gene3D G3DSA:3.40.50.300 731 934 5.0E-91 T 12-10-2018 HW35_08895 9077d0cc0e53930f1bde49b4a1a85914 976 Gene3D G3DSA:1.20.120.850 745 969 5.0E-91 T 12-10-2018 HW35_08895 9077d0cc0e53930f1bde49b4a1a85914 976 SMART SM00487 485 690 3.5E-30 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_08895 9077d0cc0e53930f1bde49b4a1a85914 976 Pfam PF00176 SNF2 family N-terminal domain 501 791 9.4E-62 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 Gene3D G3DSA:3.40.50.620 1 160 4.6E-59 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 Pfam PF01467 Cytidylyltransferase-like 7 135 1.9E-18 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 1.4E-62 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 3.8E-53 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 3.8E-53 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 3.8E-53 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 3.8E-53 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 3.8E-53 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 SUPERFAMILY SSF52374 3 157 9.38E-45 T 12-10-2018 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 78 3.0E-4 T 12-10-2018 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 36.301 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HW35_16190 efa2b231142046b2fe2f9c291aeb9ba9 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 63 1.6E-17 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HW35_16800 0711cea253b8b5ccd8d88d7e22c3e78b 420 Pfam PF13180 PDZ domain 206 265 1.2E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_16800 0711cea253b8b5ccd8d88d7e22c3e78b 420 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 418 2.6E-112 T 12-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 HW35_16800 0711cea253b8b5ccd8d88d7e22c3e78b 420 Gene3D G3DSA:2.30.42.10 201 290 1.6E-21 T 12-10-2018 HW35_16800 0711cea253b8b5ccd8d88d7e22c3e78b 420 SUPERFAMILY SSF50156 173 267 1.6E-18 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 HW35_16800 0711cea253b8b5ccd8d88d7e22c3e78b 420 SMART SM00228 188 258 1.7E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_16800 0711cea253b8b5ccd8d88d7e22c3e78b 420 Pfam PF02163 Peptidase family M50 6 405 1.9E-79 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 Gene3D G3DSA:3.40.50.300 94 371 1.6E-126 T 12-10-2018 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 6.2E-260 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 493 1.7E-47 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 SUPERFAMILY SSF52540 95 370 1.52E-98 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 Gene3D G3DSA:2.40.30.20 1 93 5.5E-38 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 SUPERFAMILY SSF47917 372 499 2.28E-48 T 12-10-2018 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 3.1E-72 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 2.1E-21 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 52.033 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 SUPERFAMILY SSF50615 10 94 2.16E-31 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 Gene3D G3DSA:1.20.150.20 372 499 9.6E-53 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09095 638b2999db6fc5a15d444674b8d6bd5b 502 PIRSF PIRSF039088 1 501 8.3E-254 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 Pfam PF02978 Signal peptide binding domain 329 427 2.0E-33 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 Gene3D G3DSA:1.10.260.30 328 447 1.7E-44 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 SMART SM00963 2 87 1.3E-34 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 437 35.932 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 SUPERFAMILY SSF47446 329 430 4.25E-37 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 Gene3D G3DSA:1.20.120.140 6 307 7.0E-132 T 12-10-2018 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 SMART SM00962 101 297 3.1E-123 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 1.7E-80 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 Gene3D G3DSA:3.40.50.300 91 286 7.0E-132 T 12-10-2018 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 8.3E-193 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 SMART SM00382 100 275 2.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 5.2E-23 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_16675 4066374d8bd2620bd5f9e35bc93fccc9 450 SUPERFAMILY SSF52540 43 355 6.57E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09160 3cd45b69ab0a4c5aa026d2bd75c74d27 152 SMART SM00226 2 143 7.8E-34 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I HW35_09160 3cd45b69ab0a4c5aa026d2bd75c74d27 152 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 138 1.6E-32 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I HW35_09160 3cd45b69ab0a4c5aa026d2bd75c74d27 152 SUPERFAMILY SSF52788 1 144 3.14E-40 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily HW35_09160 3cd45b69ab0a4c5aa026d2bd75c74d27 152 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.3E-10 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HW35_09160 3cd45b69ab0a4c5aa026d2bd75c74d27 152 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 115 130 2.3E-10 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HW35_09160 3cd45b69ab0a4c5aa026d2bd75c74d27 152 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 74 89 2.3E-10 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HW35_09160 3cd45b69ab0a4c5aa026d2bd75c74d27 152 Gene3D G3DSA:3.40.50.2300 2 150 8.4E-55 T 12-10-2018 HW35_08675 df44318c69a1e455b4f332ddf16d40ae 196 Pfam PF08281 Sigma-70, region 4 136 185 3.3E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_08675 df44318c69a1e455b4f332ddf16d40ae 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 51 189 9.6E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_08675 df44318c69a1e455b4f332ddf16d40ae 196 SUPERFAMILY SSF88659 100 189 2.8E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_08675 df44318c69a1e455b4f332ddf16d40ae 196 Gene3D G3DSA:1.20.140.160 69 191 2.4E-15 T 12-10-2018 HW35_13085 e8933cd17107d8b3d1cb0ac60421a5e2 294 Gene3D G3DSA:3.40.50.720 5 283 1.5E-125 T 12-10-2018 HW35_13085 e8933cd17107d8b3d1cb0ac60421a5e2 294 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 111 2.9E-11 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HW35_13085 e8933cd17107d8b3d1cb0ac60421a5e2 294 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 3 289 4.0E-139 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 HW35_13085 e8933cd17107d8b3d1cb0ac60421a5e2 294 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 126 264 1.0E-64 T 12-10-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 HW35_13085 e8933cd17107d8b3d1cb0ac60421a5e2 294 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 294 126.815 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 HW35_13085 e8933cd17107d8b3d1cb0ac60421a5e2 294 PIRSF PIRSF015689 1 293 7.3E-133 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 HW35_13085 e8933cd17107d8b3d1cb0ac60421a5e2 294 SUPERFAMILY SSF51735 3 150 1.67E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_13085 e8933cd17107d8b3d1cb0ac60421a5e2 294 SUPERFAMILY SSF55347 126 265 6.28E-60 T 12-10-2018 HW35_13085 e8933cd17107d8b3d1cb0ac60421a5e2 294 Gene3D G3DSA:3.30.360.10 126 264 1.5E-125 T 12-10-2018 HW35_13085 e8933cd17107d8b3d1cb0ac60421a5e2 294 SMART SM00859 5 118 7.9E-12 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HW35_09175 ebbc6471a4dce3620825fece591eb05b 148 Gene3D G3DSA:3.40.630.30 2 139 1.8E-12 T 12-10-2018 HW35_09175 ebbc6471a4dce3620825fece591eb05b 148 SUPERFAMILY SSF55729 4 123 4.65E-9 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_03380 384f75facb61f06888e13a4a3bd16da4 492 PIRSF PIRSF007466 1 492 1.5E-267 T 12-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 HW35_03380 384f75facb61f06888e13a4a3bd16da4 492 SUPERFAMILY SSF52540 19 225 5.49E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03380 384f75facb61f06888e13a4a3bd16da4 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 4.4E-266 T 12-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 HW35_03380 384f75facb61f06888e13a4a3bd16da4 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 2.8E-227 T 12-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 HW35_03380 384f75facb61f06888e13a4a3bd16da4 492 Gene3D G3DSA:3.40.50.300 12 236 1.4E-10 T 12-10-2018 HW35_16500 18300ce623ef53786f38bcbf167e960a 238 SUPERFAMILY SSF51366 3 233 4.12E-69 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HW35_16500 18300ce623ef53786f38bcbf167e960a 238 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 228 1.4E-45 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16500 18300ce623ef53786f38bcbf167e960a 238 SMART SM00934 4 229 1.2E-85 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16500 18300ce623ef53786f38bcbf167e960a 238 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 234 38.13 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16500 18300ce623ef53786f38bcbf167e960a 238 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16500 18300ce623ef53786f38bcbf167e960a 238 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 5 228 4.1E-59 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16500 18300ce623ef53786f38bcbf167e960a 238 Gene3D G3DSA:3.20.20.70 1 237 3.3E-77 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_09705 d88096d49fd90e27d61db41feafd391c 529 SUPERFAMILY SSF52540 5 225 3.33E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09705 d88096d49fd90e27d61db41feafd391c 529 SMART SM00382 304 489 1.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_09705 d88096d49fd90e27d61db41feafd391c 529 SMART SM00382 31 227 1.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_09705 d88096d49fd90e27d61db41feafd391c 529 Gene3D G3DSA:3.40.50.300 2 239 7.6E-61 T 12-10-2018 HW35_09705 d88096d49fd90e27d61db41feafd391c 529 SUPERFAMILY SSF52540 272 507 3.3E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09705 d88096d49fd90e27d61db41feafd391c 529 Pfam PF00005 ABC transporter 22 160 1.3E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_09705 d88096d49fd90e27d61db41feafd391c 529 Gene3D G3DSA:3.40.50.300 276 526 1.1E-65 T 12-10-2018 HW35_09705 d88096d49fd90e27d61db41feafd391c 529 ProSitePatterns PS00211 ABC transporters family signature. 413 427 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_09705 d88096d49fd90e27d61db41feafd391c 529 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_09705 d88096d49fd90e27d61db41feafd391c 529 Pfam PF00005 ABC transporter 296 440 1.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_16705 f6ae1722cdea142e98c6d916cf0f1345 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16705 f6ae1722cdea142e98c6d916cf0f1345 114 PIRSF PIRSF002191 1 114 1.1E-51 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16705 f6ae1722cdea142e98c6d916cf0f1345 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 8.7E-52 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16705 f6ae1722cdea142e98c6d916cf0f1345 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 32.887 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16705 f6ae1722cdea142e98c6d916cf0f1345 114 Gene3D G3DSA:2.30.30.790 3 114 4.5E-15 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16705 f6ae1722cdea142e98c6d916cf0f1345 114 SUPERFAMILY SSF50104 2 113 1.1E-48 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily HW35_16705 f6ae1722cdea142e98c6d916cf0f1345 114 Pfam PF01245 Ribosomal protein L19 4 112 6.0E-54 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16705 f6ae1722cdea142e98c6d916cf0f1345 114 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16705 f6ae1722cdea142e98c6d916cf0f1345 114 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_16705 f6ae1722cdea142e98c6d916cf0f1345 114 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 SUPERFAMILY SSF55681 117 422 4.19E-106 T 12-10-2018 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 5.9E-181 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 1.1E-35 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 5.4E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 5.4E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 5.4E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 5.4E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 5.4E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 43.976 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 SUPERFAMILY SSF46589 1 113 1.31E-31 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 Gene3D G3DSA:3.30.930.10 106 426 8.1E-128 T 12-10-2018 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 3.2E-32 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 PIRSF PIRSF001529 1 425 1.7E-191 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HW35_10060 4dabcbc6e94f992bc06756114f33b232 426 Gene3D G3DSA:1.10.287.40 1 105 1.9E-26 T 12-10-2018 HW35_01440 edf4c21c9c2a6b4925e13197b1f90d74 195 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 10 34 - T 12-10-2018 IPR001455 TusA-like domain HW35_01440 edf4c21c9c2a6b4925e13197b1f90d74 195 SUPERFAMILY SSF64307 3 77 2.09E-23 T 12-10-2018 IPR036868 TusA-like domain superfamily HW35_01440 edf4c21c9c2a6b4925e13197b1f90d74 195 Gene3D G3DSA:3.40.250.10 82 192 4.0E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_01440 edf4c21c9c2a6b4925e13197b1f90d74 195 Pfam PF01206 Sulfurtransferase TusA 9 77 1.9E-21 T 12-10-2018 IPR001455 TusA-like domain HW35_01440 edf4c21c9c2a6b4925e13197b1f90d74 195 Gene3D G3DSA:3.30.110.40 3 78 3.9E-28 T 12-10-2018 IPR036868 TusA-like domain superfamily HW35_01440 edf4c21c9c2a6b4925e13197b1f90d74 195 Pfam PF00581 Rhodanese-like domain 94 183 2.8E-17 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_01440 edf4c21c9c2a6b4925e13197b1f90d74 195 SMART SM00450 93 188 3.9E-25 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_01440 edf4c21c9c2a6b4925e13197b1f90d74 195 SUPERFAMILY SSF52821 86 185 6.68E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_10225 7b92be832db0a5cacdf7ebc65d633398 292 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 3 280 9.0E-112 T 12-10-2018 IPR008764 Peptidase U57, YabG HW35_10225 7b92be832db0a5cacdf7ebc65d633398 292 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 4 286 7.0E-136 T 12-10-2018 IPR008764 Peptidase U57, YabG HW35_10225 7b92be832db0a5cacdf7ebc65d633398 292 Pfam PF05582 YabG peptidase U57 4 285 1.5E-116 T 12-10-2018 IPR008764 Peptidase U57, YabG HW35_10225 7b92be832db0a5cacdf7ebc65d633398 292 PIRSF PIRSF011575 2 290 1.1E-119 T 12-10-2018 IPR008764 Peptidase U57, YabG HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 Gene3D G3DSA:3.40.50.300 337 752 4.2E-144 T 12-10-2018 HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 Pfam PF14490 Helix-hairpin-helix containing domain 158 249 2.3E-32 T 12-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 SUPERFAMILY SSF52540 198 517 5.24E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 Pfam PF13604 AAA domain 345 554 7.5E-52 T 12-10-2018 HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 24 756 1.1E-262 T 12-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 Pfam PF13538 UvrD-like helicase C-terminal domain 682 730 8.8E-18 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 Gene3D G3DSA:2.30.30.940 603 683 4.2E-144 T 12-10-2018 HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 Gene3D G3DSA:1.10.10.2220 200 297 2.8E-15 T 12-10-2018 HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 14 789 29.784 T 12-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 Gene3D G3DSA:3.40.50.300 517 746 4.2E-144 T 12-10-2018 HW35_04800 b9dae36bedb698d7b90cb477bf5e1a73 807 SUPERFAMILY SSF52540 469 751 1.43E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10290 88c27f790c8cb4b7aa6002f976d91a4e 178 PIRSF PIRSF026579 1 178 1.4E-95 T 12-10-2018 IPR014213 Sporulation stage V, protein T HW35_10290 88c27f790c8cb4b7aa6002f976d91a4e 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HW35_10290 88c27f790c8cb4b7aa6002f976d91a4e 178 Gene3D G3DSA:2.10.260.10 1 49 3.8E-24 T 12-10-2018 HW35_10290 88c27f790c8cb4b7aa6002f976d91a4e 178 SMART SM00966 8 52 1.1E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HW35_10290 88c27f790c8cb4b7aa6002f976d91a4e 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 177 5.0E-90 T 12-10-2018 IPR014213 Sporulation stage V, protein T HW35_10290 88c27f790c8cb4b7aa6002f976d91a4e 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.1E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HW35_10290 88c27f790c8cb4b7aa6002f976d91a4e 178 SUPERFAMILY SSF89447 1 52 9.03E-15 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily HW35_10290 88c27f790c8cb4b7aa6002f976d91a4e 178 Gene3D G3DSA:3.30.450.40 56 178 7.7E-46 T 12-10-2018 IPR029016 GAF-like domain superfamily HW35_10290 88c27f790c8cb4b7aa6002f976d91a4e 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 177 4.7E-46 T 12-10-2018 IPR039472 Sporulation stage V protein T, GAF domain HW35_13045 c9d68b4b8dfbc0033b790e71948bcb94 265 SUPERFAMILY SSF56529 9 259 9.16E-70 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 HW35_13045 c9d68b4b8dfbc0033b790e71948bcb94 265 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 104 257 5.5E-10 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 HW35_13045 c9d68b4b8dfbc0033b790e71948bcb94 265 Gene3D G3DSA:3.90.850.10 3 260 7.7E-76 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 142 1.3E-24 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 176 343 1.0E-26 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 1.5E-181 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 1.0E-36 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 SUPERFAMILY SSF52540 5 167 2.96E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 Gene3D G3DSA:3.40.50.300 170 352 6.4E-55 T 12-10-2018 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 1.2E-25 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 Pfam PF01926 50S ribosome-binding GTPase 179 295 1.4E-26 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 Gene3D G3DSA:3.30.300.20 353 436 1.2E-37 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 Hamap MF_00195 GTPase Der [der]. 3 436 41.863 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 Gene3D G3DSA:3.40.50.300 1 162 9.1E-47 T 12-10-2018 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 PIRSF PIRSF006485 2 436 8.4E-179 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 SUPERFAMILY SSF52540 138 435 1.49E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 2.4E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_03400 d4e784fe4393987df7c24fc393693cd4 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 2.4E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_06975 450983e205661319b8455d26c693534a 254 SUPERFAMILY SSF56784 3 252 2.49E-73 T 12-10-2018 IPR036412 HAD-like superfamily HW35_06975 450983e205661319b8455d26c693534a 254 PIRSF PIRSF000915 1 252 4.0E-63 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA HW35_06975 450983e205661319b8455d26c693534a 254 Gene3D G3DSA:3.40.50.1000 5 230 2.3E-87 T 12-10-2018 IPR023214 HAD superfamily HW35_06975 450983e205661319b8455d26c693534a 254 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 252 2.7E-124 T 12-10-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 HW35_06975 450983e205661319b8455d26c693534a 254 Pfam PF13242 HAD-hyrolase-like 179 250 3.4E-20 T 12-10-2018 HW35_06975 450983e205661319b8455d26c693534a 254 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 228 8.1E-44 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA HW35_06975 450983e205661319b8455d26c693534a 254 Gene3D G3DSA:3.40.50.1000 84 179 2.3E-87 T 12-10-2018 IPR023214 HAD superfamily HW35_06975 450983e205661319b8455d26c693534a 254 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 107 1.5E-28 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA HW35_17140 4eb439533437a3a9be52761e960998d1 319 Pfam PF01715 IPP transferase 40 286 3.1E-88 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 HW35_17140 4eb439533437a3a9be52761e960998d1 319 SUPERFAMILY SSF52540 8 152 1.41E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17140 4eb439533437a3a9be52761e960998d1 319 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 7 309 32.07 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 HW35_17140 4eb439533437a3a9be52761e960998d1 319 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 8 293 1.2E-113 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 HW35_17140 4eb439533437a3a9be52761e960998d1 319 Gene3D G3DSA:1.10.20.140 114 187 6.1E-110 T 12-10-2018 HW35_17140 4eb439533437a3a9be52761e960998d1 319 SUPERFAMILY SSF52540 6 268 3.83E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17140 4eb439533437a3a9be52761e960998d1 319 Gene3D G3DSA:3.40.50.300 11 289 6.1E-110 T 12-10-2018 HW35_13450 46cc25061813d4c0d4b8c082d2fb2cff 100 SUPERFAMILY SSF46689 8 90 7.17E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_13450 46cc25061813d4c0d4b8c082d2fb2cff 100 Gene3D G3DSA:1.10.10.60 12 92 3.1E-5 T 12-10-2018 HW35_13450 46cc25061813d4c0d4b8c082d2fb2cff 100 Pfam PF13518 Helix-turn-helix domain 16 63 4.2E-8 T 12-10-2018 HW35_03600 6885a2675e09248179faa2321f8184c7 294 SUPERFAMILY SSF54719 174 289 2.23E-42 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 182 284 2.6E-36 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 251 258 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 Gene3D G3DSA:1.10.287.990 112 175 2.8E-25 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 95 175 1.0E-28 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 SUPERFAMILY SSF46609 94 180 2.88E-32 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 Gene3D G3DSA:2.40.500.20 176 293 4.7E-45 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 PRINTS PR01703 Manganese superoxide dismutase signature 119 132 1.5E-20 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 PRINTS PR01703 Manganese superoxide dismutase signature 158 171 1.5E-20 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 PRINTS PR01703 Manganese superoxide dismutase signature 98 109 1.5E-20 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 PRINTS PR01703 Manganese superoxide dismutase signature 211 219 1.5E-20 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_03600 6885a2675e09248179faa2321f8184c7 294 PRINTS PR01703 Manganese superoxide dismutase signature 249 261 1.5E-20 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 HW35_13445 58e8b52e87d0b5f4a37cfc5215cf9e70 290 Gene3D G3DSA:3.30.420.10 127 278 5.1E-11 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_13445 58e8b52e87d0b5f4a37cfc5215cf9e70 290 Pfam PF00665 Integrase core domain 132 243 1.5E-23 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_13445 58e8b52e87d0b5f4a37cfc5215cf9e70 290 Pfam PF13276 HTH-like domain 56 108 3.8E-19 T 12-10-2018 IPR025948 HTH-like domain HW35_13445 58e8b52e87d0b5f4a37cfc5215cf9e70 290 SUPERFAMILY SSF53098 124 283 1.67E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_09155 fedb5c066b82c62e99f3f60afcdc7cf9 148 Gene3D G3DSA:3.40.1400.10 1 147 9.0E-59 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HW35_09155 fedb5c066b82c62e99f3f60afcdc7cf9 148 Pfam PF02502 Ribose/Galactose Isomerase 3 140 2.7E-56 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HW35_09155 fedb5c066b82c62e99f3f60afcdc7cf9 148 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 1.1E-59 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HW35_09155 fedb5c066b82c62e99f3f60afcdc7cf9 148 SUPERFAMILY SSF89623 2 144 1.31E-58 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HW35_09155 fedb5c066b82c62e99f3f60afcdc7cf9 148 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 1.3E-51 T 12-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 HW35_09155 fedb5c066b82c62e99f3f60afcdc7cf9 148 PIRSF PIRSF005384 1 147 2.6E-58 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HW35_07545 c9de48298769b36cbabd674caf25771a 223 Pfam PF02080 TrkA-C domain 154 220 2.3E-13 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HW35_07545 c9de48298769b36cbabd674caf25771a 223 Gene3D G3DSA:3.30.70.1450 143 223 5.1E-26 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_07545 c9de48298769b36cbabd674caf25771a 223 SUPERFAMILY SSF116726 136 220 8.76E-20 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_07545 c9de48298769b36cbabd674caf25771a 223 SUPERFAMILY SSF51735 9 139 2.13E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_07545 c9de48298769b36cbabd674caf25771a 223 Gene3D G3DSA:3.40.50.720 5 142 1.3E-36 T 12-10-2018 HW35_07545 c9de48298769b36cbabd674caf25771a 223 Pfam PF02254 TrkA-N domain 10 125 3.4E-26 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HW35_12540 cdc2432289e77adaaf6ee4136852f1a1 333 Gene3D G3DSA:2.20.150.10 20 116 7.7E-99 T 12-10-2018 IPR023314 5-Dehydro-2-deoxygluconokinase-like superfamily KEGG: 00562+2.7.1.92 HW35_12540 cdc2432289e77adaaf6ee4136852f1a1 333 Gene3D G3DSA:3.40.1190.20 15 304 7.7E-99 T 12-10-2018 IPR029056 Ribokinase-like HW35_12540 cdc2432289e77adaaf6ee4136852f1a1 333 Hamap MF_01668 5-dehydro-2-deoxygluconokinase [iolC]. 8 329 54.995 T 12-10-2018 IPR022841 5-dehydro-2-deoxygluconokinase, Firmicutes GO:0016310|GO:0047590 KEGG: 00562+2.7.1.92 HW35_12540 cdc2432289e77adaaf6ee4136852f1a1 333 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 269 282 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HW35_12540 cdc2432289e77adaaf6ee4136852f1a1 333 Pfam PF00294 pfkB family carbohydrate kinase 14 317 2.1E-65 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB HW35_12540 cdc2432289e77adaaf6ee4136852f1a1 333 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 12 325 1.4E-127 T 12-10-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 HW35_12540 cdc2432289e77adaaf6ee4136852f1a1 333 SUPERFAMILY SSF53613 11 325 9.35E-76 T 12-10-2018 IPR029056 Ribokinase-like HW35_06400 cc91502551484d8f65e71e92ed3d553c 466 SUPERFAMILY SSF56322 48 464 2.62E-96 T 12-10-2018 IPR005801 ADC synthase GO:0009058 HW35_06400 cc91502551484d8f65e71e92ed3d553c 466 Gene3D G3DSA:3.60.120.10 7 465 1.5E-104 T 12-10-2018 IPR005801 ADC synthase GO:0009058 HW35_06400 cc91502551484d8f65e71e92ed3d553c 466 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 113 463 2.4E-108 T 12-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 HW35_06400 cc91502551484d8f65e71e92ed3d553c 466 Pfam PF00425 chorismate binding enzyme 203 455 1.9E-71 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal HW35_06400 cc91502551484d8f65e71e92ed3d553c 466 Hamap MF_01935 Isochorismate synthase MenF [menF]. 1 465 28.359 T 12-10-2018 IPR034681 Isochorismate synthase MenF GO:0008909|GO:0009234 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 Hamap MF_00456 Glutamate 5-kinase [proB]. 3 258 34.698 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 SUPERFAMILY SSF88697 276 365 2.6E-16 T 12-10-2018 IPR015947 PUA-like superfamily HW35_01135 a078b396bc5af121668168d29aebf8b7 369 SUPERFAMILY SSF53633 3 253 4.45E-64 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_01135 a078b396bc5af121668168d29aebf8b7 369 SMART SM00359 276 358 3.2E-15 T 12-10-2018 IPR002478 PUA domain GO:0003723 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 ProSitePatterns PS00902 Glutamate 5-kinase signature. 205 222 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 Pfam PF00696 Amino acid kinase family 3 231 1.4E-43 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 Pfam PF01472 PUA domain 277 347 9.9E-19 T 12-10-2018 IPR002478 PUA domain GO:0003723 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 TIGRFAM TIGR01027 proB: glutamate 5-kinase 5 365 1.2E-132 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 PRINTS PR00474 Glutamate 5-kinase family signature 114 135 2.7E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 PRINTS PR00474 Glutamate 5-kinase family signature 74 102 2.7E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 PRINTS PR00474 Glutamate 5-kinase family signature 40 54 2.7E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 PRINTS PR00474 Glutamate 5-kinase family signature 207 227 2.7E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 PRINTS PR00474 Glutamate 5-kinase family signature 146 173 2.7E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 Gene3D G3DSA:2.30.130.10 265 366 1.1E-26 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 HW35_01135 a078b396bc5af121668168d29aebf8b7 369 Gene3D G3DSA:3.40.1160.10 1 259 2.7E-81 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_01135 a078b396bc5af121668168d29aebf8b7 369 PIRSF PIRSF000729 1 367 4.5E-133 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 SMART SM00433 40 633 0.0 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 8 640 99.76 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR00418 DNA topoisomerase II family signature 40 55 1.4E-74 T 12-10-2018 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR00418 DNA topoisomerase II family signature 530 542 1.4E-74 T 12-10-2018 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR00418 DNA topoisomerase II family signature 118 132 1.4E-74 T 12-10-2018 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR00418 DNA topoisomerase II family signature 426 440 1.4E-74 T 12-10-2018 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR00418 DNA topoisomerase II family signature 75 88 1.4E-74 T 12-10-2018 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR00418 DNA topoisomerase II family signature 274 287 1.4E-74 T 12-10-2018 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR00418 DNA topoisomerase II family signature 510 527 1.4E-74 T 12-10-2018 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR00418 DNA topoisomerase II family signature 572 588 1.4E-74 T 12-10-2018 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR00418 DNA topoisomerase II family signature 492 508 1.4E-74 T 12-10-2018 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 Gene3D G3DSA:3.30.230.10 226 404 4.7E-76 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 SUPERFAMILY SSF55874 11 223 1.07E-73 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 Gene3D G3DSA:3.30.565.10 7 225 4.0E-94 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 ProSitePatterns PS00177 DNA topoisomerase II signature. 428 436 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 Pfam PF00204 DNA gyrase B 227 396 1.1E-65 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 SMART SM00387 36 180 2.3E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 11 640 0.0 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 SUPERFAMILY SSF56719 400 632 3.66E-93 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 629 1.1E-31 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 177 8.2E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR01159 DNA gyrase subunit B signature 380 400 1.6E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR01159 DNA gyrase subunit B signature 609 625 1.6E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR01159 DNA gyrase subunit B signature 593 605 1.6E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR01159 DNA gyrase subunit B signature 11 21 1.6E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR01159 DNA gyrase subunit B signature 318 334 1.6E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR01159 DNA gyrase subunit B signature 186 201 1.6E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR01159 DNA gyrase subunit B signature 201 214 1.6E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR01159 DNA gyrase subunit B signature 226 248 1.6E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR01159 DNA gyrase subunit B signature 366 380 1.6E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 PRINTS PR01159 DNA gyrase subunit B signature 476 485 1.6E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 SUPERFAMILY SSF54211 227 397 2.47E-64 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 Gene3D G3DSA:3.40.50.670 405 640 1.3E-112 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HW35_09995 fe94125607ffb155b374b036ca2fe82e 640 Pfam PF01751 Toprim domain 425 536 5.0E-19 T 12-10-2018 IPR006171 TOPRIM domain HW35_01755 ed470c23aa3c36cab9bcd9f2550c081e 369 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 50 163 5.6E-10 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HW35_01755 ed470c23aa3c36cab9bcd9f2550c081e 369 SUPERFAMILY SSF52490 4 192 7.98E-23 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 HW35_01755 ed470c23aa3c36cab9bcd9f2550c081e 369 Gene3D G3DSA:3.40.50.1440 2 261 7.1E-49 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 HW35_01755 ed470c23aa3c36cab9bcd9f2550c081e 369 SMART SM00864 3 196 1.9E-4 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HW35_02775 9d006ab2ec45efed1f31834405393c16 178 SUPERFAMILY SSF55068 2 168 8.37E-74 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 HW35_02775 9d006ab2ec45efed1f31834405393c16 178 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 157 8.4E-66 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 HW35_02775 9d006ab2ec45efed1f31834405393c16 178 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 164 37.331 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 HW35_02775 9d006ab2ec45efed1f31834405393c16 178 Gene3D G3DSA:3.30.1060.10 1 165 3.1E-68 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 HW35_02775 9d006ab2ec45efed1f31834405393c16 178 Pfam PF01625 Peptide methionine sulfoxide reductase 8 158 5.1E-62 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 HW35_06685 02fb29ab6e43379460919602338155f3 187 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 108 2.4E-11 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_06685 02fb29ab6e43379460919602338155f3 187 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.8E-7 T 12-10-2018 HW35_06685 02fb29ab6e43379460919602338155f3 187 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 2.8E-7 T 12-10-2018 HW35_06685 02fb29ab6e43379460919602338155f3 187 Gene3D G3DSA:3.50.50.60 1 177 1.8E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_06685 02fb29ab6e43379460919602338155f3 187 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 2.8E-11 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06685 02fb29ab6e43379460919602338155f3 187 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 53 63 2.8E-11 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06685 02fb29ab6e43379460919602338155f3 187 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 98 106 2.8E-11 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06685 02fb29ab6e43379460919602338155f3 187 SUPERFAMILY SSF51905 1 174 1.37E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_13955 70013f212a3ca670f44ab71918c6053c 425 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site HW35_13955 70013f212a3ca670f44ab71918c6053c 425 Gene3D G3DSA:1.10.3860.10 1 419 5.1E-139 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 HW35_13955 70013f212a3ca670f44ab71918c6053c 425 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 5.9E-124 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 HW35_13955 70013f212a3ca670f44ab71918c6053c 425 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site HW35_13955 70013f212a3ca670f44ab71918c6053c 425 SUPERFAMILY SSF118215 6 402 9.42E-127 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 HW35_13955 70013f212a3ca670f44ab71918c6053c 425 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 8.8E-37 T 12-10-2018 HW35_13955 70013f212a3ca670f44ab71918c6053c 425 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 8.8E-37 T 12-10-2018 HW35_13955 70013f212a3ca670f44ab71918c6053c 425 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 8.8E-37 T 12-10-2018 HW35_13955 70013f212a3ca670f44ab71918c6053c 425 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 8.8E-37 T 12-10-2018 HW35_13955 70013f212a3ca670f44ab71918c6053c 425 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 8.8E-37 T 12-10-2018 HW35_13955 70013f212a3ca670f44ab71918c6053c 425 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 8.8E-37 T 12-10-2018 HW35_13955 70013f212a3ca670f44ab71918c6053c 425 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 8.8E-37 T 12-10-2018 HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 168 257 2.3E-15 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 SUPERFAMILY SSF55804 1 147 1.44E-41 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 Gene3D G3DSA:3.40.50.2300 153 267 3.3E-41 T 12-10-2018 HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 Pfam PF02378 Phosphotransferase system, EIIC 293 562 1.5E-15 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 SUPERFAMILY SSF52794 166 266 4.19E-37 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 275 616 6.6E-143 T 12-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 167 249 6.4E-30 T 12-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 133 6.4E-39 T 12-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 Gene3D G3DSA:3.40.930.10 1 148 1.1E-45 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_02580 ca7966c3429840c7adf5d4a19208a761 621 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 148 4.0E-39 T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_16955 c9ed1a29a9fb74539c366d14da968a0b 430 SUPERFAMILY SSF63411 13 220 8.73E-42 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HW35_16955 c9ed1a29a9fb74539c366d14da968a0b 430 Gene3D G3DSA:3.30.830.10 238 427 3.2E-43 T 12-10-2018 HW35_16955 c9ed1a29a9fb74539c366d14da968a0b 430 Pfam PF00675 Insulinase (Peptidase family M16) 64 152 1.9E-15 T 12-10-2018 IPR011765 Peptidase M16, N-terminal HW35_16955 c9ed1a29a9fb74539c366d14da968a0b 430 SUPERFAMILY SSF63411 240 425 1.03E-20 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HW35_16955 c9ed1a29a9fb74539c366d14da968a0b 430 Pfam PF05193 Peptidase M16 inactive domain 182 362 2.6E-21 T 12-10-2018 IPR007863 Peptidase M16, C-terminal HW35_16955 c9ed1a29a9fb74539c366d14da968a0b 430 Gene3D G3DSA:3.30.830.10 7 237 5.8E-61 T 12-10-2018 HW35_05455 84e6dda68f4bb981236c04c62011588a 325 Gene3D G3DSA:3.40.50.1220 195 324 7.0E-57 T 12-10-2018 HW35_05455 84e6dda68f4bb981236c04c62011588a 325 SUPERFAMILY SSF52467 198 317 2.29E-48 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily HW35_05455 84e6dda68f4bb981236c04c62011588a 325 PIRSF PIRSF000089 1 322 8.6E-112 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 HW35_05455 84e6dda68f4bb981236c04c62011588a 325 SUPERFAMILY SSF52402 4 190 4.47E-50 T 12-10-2018 HW35_05455 84e6dda68f4bb981236c04c62011588a 325 Pfam PF01012 Electron transfer flavoprotein domain 5 179 2.1E-43 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HW35_05455 84e6dda68f4bb981236c04c62011588a 325 Gene3D G3DSA:3.40.50.620 2 194 6.7E-56 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_05455 84e6dda68f4bb981236c04c62011588a 325 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 HW35_05455 84e6dda68f4bb981236c04c62011588a 325 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 198 281 2.2E-35 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 HW35_05455 84e6dda68f4bb981236c04c62011588a 325 SMART SM00893 5 195 8.2E-48 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HW35_17040 dd31bf8c0f3f631ebe56935e7eb7ba3a 155 SMART SM00903 10 152 4.7E-49 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 HW35_17040 dd31bf8c0f3f631ebe56935e7eb7ba3a 155 SUPERFAMILY SSF50475 2 153 4.32E-42 T 12-10-2018 HW35_17040 dd31bf8c0f3f631ebe56935e7eb7ba3a 155 Gene3D G3DSA:2.30.110.10 2 155 2.1E-45 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 HW35_17040 dd31bf8c0f3f631ebe56935e7eb7ba3a 155 Pfam PF01613 Flavin reductase like domain 10 153 3.4E-34 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 HW35_16640 19178bb27d6ef6af2363082c383688b3 315 SUPERFAMILY SSF55048 129 193 2.62E-14 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding HW35_16640 19178bb27d6ef6af2363082c383688b3 315 PIRSF PIRSF000446 1 311 4.7E-123 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 HW35_16640 19178bb27d6ef6af2363082c383688b3 315 Gene3D G3DSA:3.30.70.250 127 197 9.6E-99 T 12-10-2018 HW35_16640 19178bb27d6ef6af2363082c383688b3 315 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 314 5.1E-49 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain HW35_16640 19178bb27d6ef6af2363082c383688b3 315 Pfam PF00698 Acyl transferase domain 6 285 1.4E-39 T 12-10-2018 IPR014043 Acyl transferase HW35_16640 19178bb27d6ef6af2363082c383688b3 315 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 290 2.5E-117 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 HW35_16640 19178bb27d6ef6af2363082c383688b3 315 Gene3D G3DSA:3.40.366.10 5 286 9.6E-99 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 HW35_16640 19178bb27d6ef6af2363082c383688b3 315 SUPERFAMILY SSF52151 4 309 6.02E-83 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase HW35_10335 0c6aa901d7a5a543d5d1087b6140bbb8 824 SMART SM00332 598 803 1.2E-4 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_10335 0c6aa901d7a5a543d5d1087b6140bbb8 824 SMART SM00331 593 805 3.4E-49 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_10335 0c6aa901d7a5a543d5d1087b6140bbb8 824 Gene3D G3DSA:3.60.40.10 588 824 3.0E-49 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_10335 0c6aa901d7a5a543d5d1087b6140bbb8 824 SUPERFAMILY SSF81606 597 806 7.59E-21 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_10335 0c6aa901d7a5a543d5d1087b6140bbb8 824 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 46 805 1.2E-258 T 12-10-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_10335 0c6aa901d7a5a543d5d1087b6140bbb8 824 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 621 805 7.2E-34 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_07160 aa11daa4f119db62680efb819ae4790a 795 SUPERFAMILY SSF52096 483 792 5.97E-42 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_07160 aa11daa4f119db62680efb819ae4790a 795 SUPERFAMILY SSF48179 207 326 3.06E-21 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_07160 aa11daa4f119db62680efb819ae4790a 795 SUPERFAMILY SSF48179 358 458 4.34E-18 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_07160 aa11daa4f119db62680efb819ae4790a 795 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 206 7.4E-42 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 HW35_07160 aa11daa4f119db62680efb819ae4790a 795 Gene3D G3DSA:1.10.1040.10 210 327 7.9E-18 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HW35_07160 aa11daa4f119db62680efb819ae4790a 795 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 209 306 2.0E-9 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 HW35_07160 aa11daa4f119db62680efb819ae4790a 795 Gene3D G3DSA:3.40.50.720 2 209 2.3E-63 T 12-10-2018 HW35_07160 aa11daa4f119db62680efb819ae4790a 795 Gene3D G3DSA:3.90.226.10 484 681 9.9E-30 T 12-10-2018 HW35_07160 aa11daa4f119db62680efb819ae4790a 795 Pfam PF00378 Enoyl-CoA hydratase/isomerase 488 623 2.8E-12 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 HW35_07160 aa11daa4f119db62680efb819ae4790a 795 Gene3D G3DSA:1.10.1040.10 367 438 2.6E-7 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HW35_07160 aa11daa4f119db62680efb819ae4790a 795 SUPERFAMILY SSF51735 5 207 9.3E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_03370 eaecef951a976453889e8021a69212ad 188 SUPERFAMILY SSF55620 3 187 3.93E-79 T 12-10-2018 HW35_03370 eaecef951a976453889e8021a69212ad 188 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 187 42.935 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HW35_03370 eaecef951a976453889e8021a69212ad 188 Pfam PF01227 GTP cyclohydrolase I 9 186 7.7E-82 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HW35_03370 eaecef951a976453889e8021a69212ad 188 Gene3D G3DSA:1.10.286.10 1 54 1.2E-23 T 12-10-2018 HW35_03370 eaecef951a976453889e8021a69212ad 188 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 187 1.4E-80 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HW35_03370 eaecef951a976453889e8021a69212ad 188 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 65 81 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HW35_03370 eaecef951a976453889e8021a69212ad 188 Gene3D G3DSA:3.30.1130.10 55 188 3.2E-63 T 12-10-2018 HW35_03370 eaecef951a976453889e8021a69212ad 188 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 114 124 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 Pfam PF00106 short chain dehydrogenase 8 195 2.4E-55 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 PIRSF PIRSF000126 2 263 4.2E-62 T 12-10-2018 HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.7E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.7E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.7E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.7E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.7E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 Gene3D G3DSA:3.40.50.720 1 262 1.3E-71 T 12-10-2018 HW35_03810 028585dea78d1ddc2436f0a56e6307e6 263 SUPERFAMILY SSF51735 3 256 1.2E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_07890 5f65bfb9893874c128b1fb5b582bc3f7 497 Gene3D G3DSA:3.40.50.300 143 317 9.6E-17 T 12-10-2018 HW35_07890 5f65bfb9893874c128b1fb5b582bc3f7 497 SMART SM00490 376 457 1.5E-4 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_07890 5f65bfb9893874c128b1fb5b582bc3f7 497 Gene3D G3DSA:3.40.50.300 343 474 9.2E-21 T 12-10-2018 HW35_07890 5f65bfb9893874c128b1fb5b582bc3f7 497 Pfam PF00271 Helicase conserved C-terminal domain 358 456 1.1E-7 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_07890 5f65bfb9893874c128b1fb5b582bc3f7 497 Pfam PF04851 Type III restriction enzyme, res subunit 154 301 1.7E-7 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HW35_07890 5f65bfb9893874c128b1fb5b582bc3f7 497 SMART SM00487 150 332 1.9E-10 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_07890 5f65bfb9893874c128b1fb5b582bc3f7 497 SUPERFAMILY SSF52540 165 468 6.38E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09215 d6e2801b356f2d7883ef25fc0b10ce94 322 Gene3D G3DSA:3.40.190.90 122 283 1.8E-135 T 12-10-2018 HW35_09215 d6e2801b356f2d7883ef25fc0b10ce94 322 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 320 6.8E-157 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 HW35_09215 d6e2801b356f2d7883ef25fc0b10ce94 322 PIRSF PIRSF004532 1 320 5.2E-151 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 HW35_09215 d6e2801b356f2d7883ef25fc0b10ce94 322 Gene3D G3DSA:3.30.540.10 7 309 1.8E-135 T 12-10-2018 HW35_09215 d6e2801b356f2d7883ef25fc0b10ce94 322 SUPERFAMILY SSF56655 1 312 1.1E-112 T 12-10-2018 HW35_09215 d6e2801b356f2d7883ef25fc0b10ce94 322 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 309 1.3E-144 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 HW35_08410 7f966f766fb7c08501570a51d1333308 289 PIRSF PIRSF006483 1 288 2.4E-75 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT HW35_08410 7f966f766fb7c08501570a51d1333308 289 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 18 220 2.1E-50 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT HW35_08410 7f966f766fb7c08501570a51d1333308 289 Gene3D G3DSA:3.30.70.120 198 272 4.2E-18 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HW35_08410 7f966f766fb7c08501570a51d1333308 289 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 226 280 2.4E-20 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 HW35_15655 5bc0bf7b138d1094a93186774c64913c 582 Gene3D G3DSA:3.80.30.20 174 375 7.1E-20 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HW35_15655 5bc0bf7b138d1094a93186774c64913c 582 SMART SM00729 176 379 1.6E-21 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HW35_15655 5bc0bf7b138d1094a93186774c64913c 582 SUPERFAMILY SSF102114 156 381 5.23E-38 T 12-10-2018 HW35_15655 5bc0bf7b138d1094a93186774c64913c 582 Pfam PF04055 Radical SAM superfamily 180 343 8.3E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_15655 5bc0bf7b138d1094a93186774c64913c 582 Gene3D G3DSA:3.40.50.280 9 141 1.4E-9 T 12-10-2018 HW35_15655 5bc0bf7b138d1094a93186774c64913c 582 Pfam PF02310 B12 binding domain 9 122 2.6E-17 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 HW35_15655 5bc0bf7b138d1094a93186774c64913c 582 SUPERFAMILY SSF52242 42 147 3.69E-8 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 HW35_15655 5bc0bf7b138d1094a93186774c64913c 582 Pfam PF13311 Protein of unknown function (DUF4080) 372 548 1.6E-47 T 12-10-2018 IPR025288 Domain of unknown function DUF4080 HW35_15540 29030568caad7062a45453ab22d24701 376 Gene3D G3DSA:1.10.287.470 93 180 4.4E-45 T 12-10-2018 HW35_15540 29030568caad7062a45453ab22d24701 376 Gene3D G3DSA:2.40.30.170 47 302 4.4E-45 T 12-10-2018 HW35_15540 29030568caad7062a45453ab22d24701 376 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 367 376 5.4E-5 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 HW35_15540 29030568caad7062a45453ab22d24701 376 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 71 91 5.4E-5 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 HW35_15540 29030568caad7062a45453ab22d24701 376 Gene3D G3DSA:2.40.50.100 59 217 4.4E-45 T 12-10-2018 HW35_15540 29030568caad7062a45453ab22d24701 376 SUPERFAMILY SSF111369 68 256 1.7E-7 T 12-10-2018 HW35_15540 29030568caad7062a45453ab22d24701 376 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 44 265 3.0E-17 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HW35_15540 29030568caad7062a45453ab22d24701 376 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 375 5.5E-38 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 HW35_15540 29030568caad7062a45453ab22d24701 376 Gene3D G3DSA:2.40.420.20 43 361 4.4E-45 T 12-10-2018 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 SUPERFAMILY SSF88946 105 214 1.01E-54 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 PRINTS PR00046 Major sigma-70 factor signature 192 200 3.2E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 PRINTS PR00046 Major sigma-70 factor signature 316 328 3.2E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 PRINTS PR00046 Major sigma-70 factor signature 352 363 3.2E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 PRINTS PR00046 Major sigma-70 factor signature 168 181 3.2E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 PRINTS PR00046 Major sigma-70 factor signature 337 352 3.2E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 337 363 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Pfam PF04542 Sigma-70 region 2 144 213 3.8E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 377 34.588 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Pfam PF03979 Sigma-70 factor, region 1.1 18 89 2.3E-14 T 12-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Pfam PF00140 Sigma-70 factor, region 1.2 106 139 1.2E-18 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Gene3D G3DSA:1.10.220.120 17 77 1.7E-7 T 12-10-2018 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 168 181 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 SUPERFAMILY SSF88659 274 375 3.36E-30 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Gene3D G3DSA:1.10.10.10 217 292 5.5E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 140 365 1.1E-39 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Pfam PF04539 Sigma-70 region 3 223 299 4.0E-33 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Gene3D G3DSA:1.10.601.10 139 216 8.3E-51 T 12-10-2018 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Gene3D G3DSA:1.10.601.10 104 138 1.0E-11 T 12-10-2018 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 SUPERFAMILY SSF88659 217 290 3.14E-23 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Gene3D G3DSA:1.10.10.10 305 377 2.8E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 140 376 1.7E-125 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 HW35_04415 5527addba35a9ea266f530d46e78c5a9 377 Pfam PF04545 Sigma-70, region 4 312 365 5.2E-20 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 HW35_10600 041300b71bbabc112ab98f586ff051be 159 Pfam PF02542 YgbB family 2 155 1.9E-66 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HW35_10600 041300b71bbabc112ab98f586ff051be 159 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 36.981 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HW35_10600 041300b71bbabc112ab98f586ff051be 159 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HW35_10600 041300b71bbabc112ab98f586ff051be 159 SUPERFAMILY SSF69765 1 157 2.75E-67 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HW35_10600 041300b71bbabc112ab98f586ff051be 159 Gene3D G3DSA:3.30.1330.50 1 159 1.7E-70 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HW35_10600 041300b71bbabc112ab98f586ff051be 159 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 3.8E-73 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 Pfam PF00175 Oxidoreductase NAD-binding domain 459 565 9.7E-19 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 SUPERFAMILY SSF52343 446 601 1.44E-52 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00369 Flavodoxin signature 114 125 3.9E-14 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00369 Flavodoxin signature 66 79 3.9E-14 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00369 Flavodoxin signature 146 156 3.9E-14 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00369 Flavodoxin signature 170 189 3.9E-14 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 SUPERFAMILY SSF52218 62 208 2.73E-50 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 Gene3D G3DSA:1.20.990.10 278 386 4.2E-74 T 12-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 6 601 2.6E-268 T 12-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 Pfam PF00667 FAD binding domain 230 425 3.5E-36 T 12-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 Pfam PF00258 Flavodoxin 67 190 7.6E-31 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 Gene3D G3DSA:2.40.30.10 230 441 4.2E-74 T 12-10-2018 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PIRSF PIRSF000207 1 601 8.2E-270 T 12-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 458 477 3.5E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 496 507 3.5E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 268 278 3.5E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 527 543 3.5E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 550 558 3.5E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 421 430 3.5E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 483 492 3.5E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 388 395 3.5E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 Gene3D G3DSA:3.40.50.80 447 601 3.1E-60 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 SUPERFAMILY SSF63380 227 447 5.39E-65 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel HW35_01220 7f52b1cacbc9db8c91809daa938ac6f1 601 Gene3D G3DSA:3.40.50.360 56 216 1.0E-51 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 SMART SM00636 103 410 2.7E-31 T 12-10-2018 IPR011583 Chitinase II GO:0008061 HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 SUPERFAMILY SSF54106 2 47 2.35E-10 T 12-10-2018 HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 Gene3D G3DSA:3.10.50.10 323 381 5.2E-104 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 Pfam PF00704 Glycosyl hydrolases family 18 152 408 1.7E-25 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 Pfam PF01476 LysM domain 53 96 1.8E-7 T 12-10-2018 IPR018392 LysM domain HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 Pfam PF01476 LysM domain 4 47 4.9E-13 T 12-10-2018 IPR018392 LysM domain HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 Gene3D G3DSA:3.20.20.80 130 415 5.2E-104 T 12-10-2018 HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 SUPERFAMILY SSF54106 52 96 3.4E-9 T 12-10-2018 HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 SUPERFAMILY SSF51445 120 416 1.16E-47 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 Gene3D G3DSA:3.10.350.10 1 50 8.4E-15 T 12-10-2018 IPR036779 LysM domain superfamily HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 Gene3D G3DSA:3.10.350.10 51 106 2.0E-10 T 12-10-2018 IPR036779 LysM domain superfamily HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 SMART SM00257 3 47 4.9E-15 T 12-10-2018 IPR018392 LysM domain HW35_10080 5c17bcf6612ff2e8d592e3959c721c08 429 SMART SM00257 52 96 1.9E-6 T 12-10-2018 IPR018392 LysM domain HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 SUPERFAMILY SSF53784 1 314 1.2E-122 T 12-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 Pfam PF00365 Phosphofructokinase 3 275 3.4E-116 T 12-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.9E-88 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.9E-88 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.9E-88 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 2.9E-88 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.9E-88 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 2.9E-88 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.9E-88 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.9E-88 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.9E-88 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 49.773 T 12-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 12-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 Gene3D G3DSA:3.40.50.460 142 251 6.6E-122 T 12-10-2018 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 PIRSF PIRSF000532 1 319 2.2E-126 T 12-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 Gene3D G3DSA:3.40.50.450 3 278 6.6E-122 T 12-10-2018 HW35_05690 cddbdaacff910c444beaf588e8c3ec1c 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 8.3E-141 T 12-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 HW35_16305 7cc47eb091524d2831b753d727fe701f 487 Gene3D G3DSA:3.40.1390.10 2 96 1.2E-29 T 12-10-2018 HW35_16305 7cc47eb091524d2831b753d727fe701f 487 Pfam PF01225 Mur ligase family, catalytic domain 22 94 6.6E-13 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HW35_16305 7cc47eb091524d2831b753d727fe701f 487 SUPERFAMILY SSF63418 1 97 1.2E-27 T 12-10-2018 IPR035911 MurE/MurF, N-terminal HW35_16305 7cc47eb091524d2831b753d727fe701f 487 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 20 484 5.5E-178 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 HW35_16305 7cc47eb091524d2831b753d727fe701f 487 Gene3D G3DSA:3.90.190.20 338 487 1.9E-62 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HW35_16305 7cc47eb091524d2831b753d727fe701f 487 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 484 37.798 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 HW35_16305 7cc47eb091524d2831b753d727fe701f 487 Gene3D G3DSA:3.40.1190.10 97 336 2.2E-92 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HW35_16305 7cc47eb091524d2831b753d727fe701f 487 SUPERFAMILY SSF53623 97 331 2.75E-77 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HW35_16305 7cc47eb091524d2831b753d727fe701f 487 Pfam PF08245 Mur ligase middle domain 106 312 9.9E-59 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 HW35_16305 7cc47eb091524d2831b753d727fe701f 487 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 417 1.4E-25 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 HW35_16305 7cc47eb091524d2831b753d727fe701f 487 SUPERFAMILY SSF53244 332 486 2.88E-51 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HW35_16735 db2218e519eaa54881322ac684b01c77 293 SUPERFAMILY SSF102405 85 292 4.12E-37 T 12-10-2018 HW35_16735 db2218e519eaa54881322ac684b01c77 293 Pfam PF02481 DNA recombination-mediator protein A 76 283 2.1E-80 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 HW35_16735 db2218e519eaa54881322ac684b01c77 293 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 76 292 1.6E-80 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 HW35_16735 db2218e519eaa54881322ac684b01c77 293 Gene3D G3DSA:3.40.50.450 7 293 6.7E-97 T 12-10-2018 HW35_08800 c205b52db7d44816c554fe7084b81a1a 398 SUPERFAMILY SSF53756 111 395 1.52E-21 T 12-10-2018 HW35_08800 c205b52db7d44816c554fe7084b81a1a 398 Gene3D G3DSA:3.40.50.2000 111 218 9.8E-6 T 12-10-2018 HW35_08800 c205b52db7d44816c554fe7084b81a1a 398 Pfam PF13692 Glycosyl transferases group 1 229 347 1.6E-8 T 12-10-2018 HW35_08800 c205b52db7d44816c554fe7084b81a1a 398 Gene3D G3DSA:3.40.50.2000 219 374 1.1E-23 T 12-10-2018 HW35_09730 59c512dabc34e26ba3a6f38f48c7f916 364 Gene3D G3DSA:3.40.47.10 121 359 3.0E-117 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_09730 59c512dabc34e26ba3a6f38f48c7f916 364 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 361 1.3E-109 T 12-10-2018 IPR002155 Thiolase GO:0016747 HW35_09730 59c512dabc34e26ba3a6f38f48c7f916 364 Pfam PF00108 Thiolase, N-terminal domain 5 231 8.1E-53 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 HW35_09730 59c512dabc34e26ba3a6f38f48c7f916 364 Pfam PF02803 Thiolase, C-terminal domain 241 361 2.3E-31 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 HW35_09730 59c512dabc34e26ba3a6f38f48c7f916 364 SUPERFAMILY SSF53901 241 362 1.06E-29 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_09730 59c512dabc34e26ba3a6f38f48c7f916 364 PIRSF PIRSF000429 1 364 9.9E-104 T 12-10-2018 IPR002155 Thiolase GO:0016747 HW35_09730 59c512dabc34e26ba3a6f38f48c7f916 364 SUPERFAMILY SSF53901 4 238 7.39E-51 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_09730 59c512dabc34e26ba3a6f38f48c7f916 364 Gene3D G3DSA:3.40.47.10 5 245 3.0E-117 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_02170 6f0a5144861a0c50bf1bde4b008fa71a 67 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 6.6E-24 T 12-10-2018 IPR012452 Protein of unknown function DUF1657 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 Pfam PF00406 Adenylate kinase 5 190 6.8E-62 T 12-10-2018 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 4.3E-81 T 12-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 SUPERFAMILY SSF52540 4 213 1.81E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 PRINTS PR00094 Adenylate kinase signature 4 17 9.1E-33 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 PRINTS PR00094 Adenylate kinase signature 32 46 9.1E-33 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 PRINTS PR00094 Adenylate kinase signature 160 175 9.1E-33 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 PRINTS PR00094 Adenylate kinase signature 81 97 9.1E-33 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 PRINTS PR00094 Adenylate kinase signature 177 191 9.1E-33 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 Pfam PF05191 Adenylate kinase, active site lid 127 162 1.5E-17 T 12-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 Gene3D G3DSA:3.40.50.300 1 215 7.3E-85 T 12-10-2018 HW35_10820 1521a552d363263e1a1d27830d89a9ad 216 Hamap MF_00235 Adenylate kinase [adk]. 1 213 54.128 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HW35_03865 16ef13e11fc72c147c56428a2296001e 374 Gene3D G3DSA:1.10.287.130 307 372 4.0E-20 T 12-10-2018 HW35_03865 16ef13e11fc72c147c56428a2296001e 374 SUPERFAMILY SSF52540 49 369 3.7E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03865 16ef13e11fc72c147c56428a2296001e 374 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 61 365 4.2E-98 T 12-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_03865 16ef13e11fc72c147c56428a2296001e 374 Pfam PF03308 ArgK protein 66 336 1.1E-101 T 12-10-2018 HW35_03865 16ef13e11fc72c147c56428a2296001e 374 Gene3D G3DSA:1.20.5.170 50 94 8.2E-17 T 12-10-2018 HW35_03865 16ef13e11fc72c147c56428a2296001e 374 Gene3D G3DSA:3.40.50.300 95 304 1.6E-77 T 12-10-2018 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 Gene3D G3DSA:1.10.238.260 279 391 2.0E-40 T 12-10-2018 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 Gene3D G3DSA:3.30.160.270 392 501 1.6E-8 T 12-10-2018 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 Gene3D G3DSA:3.20.20.70 1 275 2.1E-114 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 SUPERFAMILY SSF51569 3 290 7.87E-99 T 12-10-2018 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 510 43.316 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 498 4.9E-226 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 SUPERFAMILY SSF110921 395 500 7.06E-18 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 Pfam PF00682 HMGL-like 4 272 6.9E-98 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 500 6.2E-33 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HW35_13290 8387a1bb96dbf2897eb7d1386ff7c972 514 SMART SM00917 368 501 2.4E-28 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HW35_07855 16e07a7fa6f548abd2d8c4895539a27d 327 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 326 38.082 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 HW35_07855 16e07a7fa6f548abd2d8c4895539a27d 327 Gene3D G3DSA:3.30.160.20 186 281 1.2E-101 T 12-10-2018 HW35_07855 16e07a7fa6f548abd2d8c4895539a27d 327 Pfam PF00472 RF-1 domain 188 298 8.7E-46 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HW35_07855 16e07a7fa6f548abd2d8c4895539a27d 327 Pfam PF03462 PCRF domain 2 179 6.6E-61 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 HW35_07855 16e07a7fa6f548abd2d8c4895539a27d 327 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 2 325 4.4E-167 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 HW35_07855 16e07a7fa6f548abd2d8c4895539a27d 327 Gene3D G3DSA:1.20.58.410 1 76 5.7E-17 T 12-10-2018 HW35_07855 16e07a7fa6f548abd2d8c4895539a27d 327 SUPERFAMILY SSF75620 2 324 1.44E-137 T 12-10-2018 HW35_07855 16e07a7fa6f548abd2d8c4895539a27d 327 Gene3D G3DSA:3.30.70.1660 90 318 1.2E-101 T 12-10-2018 HW35_07855 16e07a7fa6f548abd2d8c4895539a27d 327 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 205 221 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HW35_07855 16e07a7fa6f548abd2d8c4895539a27d 327 SMART SM00937 45 155 5.5E-59 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 HW35_07730 fb28039b5c447b8eb6c965de496a9df0 417 Gene3D G3DSA:3.90.1150.140 249 402 7.2E-157 T 12-10-2018 HW35_07730 fb28039b5c447b8eb6c965de496a9df0 417 Pfam PF07075 Protein of unknown function (DUF1343) 54 417 5.5E-149 T 12-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 HW35_07730 fb28039b5c447b8eb6c965de496a9df0 417 PIRSF PIRSF016719 1 417 1.9E-178 T 12-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 HW35_07730 fb28039b5c447b8eb6c965de496a9df0 417 Gene3D G3DSA:3.40.50.12170 37 417 7.2E-157 T 12-10-2018 HW35_09845 68ffc0e26ee67e49bfd82285cc8ec59e 450 Gene3D G3DSA:3.40.50.300 167 448 9.8E-120 T 12-10-2018 HW35_09845 68ffc0e26ee67e49bfd82285cc8ec59e 450 SUPERFAMILY SSF52540 183 433 1.87E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09845 68ffc0e26ee67e49bfd82285cc8ec59e 450 SUPERFAMILY SSF48024 8 119 8.5E-37 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 HW35_09845 68ffc0e26ee67e49bfd82285cc8ec59e 450 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 3.2E-35 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HW35_09845 68ffc0e26ee67e49bfd82285cc8ec59e 450 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 9 442 2.8E-185 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 HW35_09845 68ffc0e26ee67e49bfd82285cc8ec59e 450 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 2.1E-118 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 HW35_09845 68ffc0e26ee67e49bfd82285cc8ec59e 450 Gene3D G3DSA:1.10.860.10 1 166 5.6E-64 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal HW35_05915 76e44133b33b93250716a8eda974f691 390 PRINTS PR01270 Histone deacetylase superfamily signature 249 259 3.6E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 HW35_05915 76e44133b33b93250716a8eda974f691 390 PRINTS PR01270 Histone deacetylase superfamily signature 130 153 3.6E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 HW35_05915 76e44133b33b93250716a8eda974f691 390 PRINTS PR01270 Histone deacetylase superfamily signature 163 178 3.6E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 HW35_05915 76e44133b33b93250716a8eda974f691 390 Gene3D G3DSA:3.40.800.20 3 342 9.2E-103 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 HW35_05915 76e44133b33b93250716a8eda974f691 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 9.1E-43 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 HW35_05915 76e44133b33b93250716a8eda974f691 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 351 370 9.1E-43 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 HW35_05915 76e44133b33b93250716a8eda974f691 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 107 120 9.1E-43 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 HW35_05915 76e44133b33b93250716a8eda974f691 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 86 100 9.1E-43 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 HW35_05915 76e44133b33b93250716a8eda974f691 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 274 290 9.1E-43 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 HW35_05915 76e44133b33b93250716a8eda974f691 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 334 350 9.1E-43 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 HW35_05915 76e44133b33b93250716a8eda974f691 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 313 332 9.1E-43 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 HW35_05915 76e44133b33b93250716a8eda974f691 390 SUPERFAMILY SSF52768 5 370 3.6E-106 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily HW35_05915 76e44133b33b93250716a8eda974f691 390 Pfam PF00850 Histone deacetylase domain 22 316 2.2E-77 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 HW35_12365 bc3c57e3d732774ade03d942a9f49977 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_12365 bc3c57e3d732774ade03d942a9f49977 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_12365 bc3c57e3d732774ade03d942a9f49977 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_12365 bc3c57e3d732774ade03d942a9f49977 293 Gene3D G3DSA:3.40.190.10 163 263 2.7E-24 T 12-10-2018 HW35_12365 bc3c57e3d732774ade03d942a9f49977 293 Gene3D G3DSA:1.10.10.10 1 89 4.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_12365 bc3c57e3d732774ade03d942a9f49977 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_12365 bc3c57e3d732774ade03d942a9f49977 293 SUPERFAMILY SSF53850 87 288 2.34E-28 T 12-10-2018 HW35_12365 bc3c57e3d732774ade03d942a9f49977 293 Gene3D G3DSA:3.40.190.10 90 283 2.7E-24 T 12-10-2018 HW35_12365 bc3c57e3d732774ade03d942a9f49977 293 SUPERFAMILY SSF46785 1 109 6.68E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_12365 bc3c57e3d732774ade03d942a9f49977 293 Pfam PF03466 LysR substrate binding domain 86 287 2.2E-32 T 12-10-2018 IPR005119 LysR, substrate-binding HW35_02315 b201afc8775828ef0d4df01875d41f63 109 Pfam PF01527 Transposase 3 73 7.4E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_02315 b201afc8775828ef0d4df01875d41f63 109 SUPERFAMILY SSF46689 4 90 9.86E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_02315 b201afc8775828ef0d4df01875d41f63 109 Gene3D G3DSA:1.10.10.60 9 87 4.7E-9 T 12-10-2018 HW35_17545 a2e8b2aa60d4753b952c187947008305 381 SUPERFAMILY SSF56300 1 317 2.89E-52 T 12-10-2018 HW35_17545 a2e8b2aa60d4753b952c187947008305 381 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 240 1.0E-46 T 12-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 HW35_17545 a2e8b2aa60d4753b952c187947008305 381 Gene3D G3DSA:3.60.21.10 1 257 7.4E-75 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like HW35_17545 a2e8b2aa60d4753b952c187947008305 381 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 265 354 2.5E-12 T 12-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain HW35_17545 a2e8b2aa60d4753b952c187947008305 381 Pfam PF00149 Calcineurin-like phosphoesterase 1 176 3.1E-16 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 HW35_17190 a3296434e2201b2233f54673e7b32233 215 Pfam PF00239 Resolvase, N terminal domain 3 147 4.1E-25 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HW35_17190 a3296434e2201b2233f54673e7b32233 215 Gene3D G3DSA:3.40.50.1390 1 155 1.4E-29 T 12-10-2018 HW35_17190 a3296434e2201b2233f54673e7b32233 215 SMART SM00857 3 149 3.6E-34 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HW35_17190 a3296434e2201b2233f54673e7b32233 215 SUPERFAMILY SSF53041 1 148 2.09E-26 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 HW35_15115 4dd7eb9f8f6a63b5fa72b920c9ae38e2 615 SUPERFAMILY SSF52402 231 576 9.67E-70 T 12-10-2018 HW35_15115 4dd7eb9f8f6a63b5fa72b920c9ae38e2 615 Pfam PF00733 Asparagine synthase 241 579 5.7E-91 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 HW35_15115 4dd7eb9f8f6a63b5fa72b920c9ae38e2 615 PIRSF PIRSF001589 1 611 8.8E-139 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 HW35_15115 4dd7eb9f8f6a63b5fa72b920c9ae38e2 615 Pfam PF13537 Glutamine amidotransferase domain 48 169 3.4E-44 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain HW35_15115 4dd7eb9f8f6a63b5fa72b920c9ae38e2 615 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 534 3.2E-165 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 HW35_15115 4dd7eb9f8f6a63b5fa72b920c9ae38e2 615 Gene3D G3DSA:3.60.20.10 2 183 7.0E-60 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HW35_15115 4dd7eb9f8f6a63b5fa72b920c9ae38e2 615 SUPERFAMILY SSF56235 1 226 2.06E-62 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HW35_10635 4312e5dd144de57f5abb444f6beb42f3 216 SUPERFAMILY SSF88946 16 105 2.22E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_10635 4312e5dd144de57f5abb444f6beb42f3 216 Pfam PF04542 Sigma-70 region 2 36 105 1.1E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_10635 4312e5dd144de57f5abb444f6beb42f3 216 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HW35_10635 4312e5dd144de57f5abb444f6beb42f3 216 PIRSF PIRSF002939 2 216 2.0E-109 T 12-10-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 HW35_10635 4312e5dd144de57f5abb444f6beb42f3 216 SMART SM00421 160 209 0.0053 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_10635 4312e5dd144de57f5abb444f6beb42f3 216 SUPERFAMILY SSF88659 123 209 7.59E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_10635 4312e5dd144de57f5abb444f6beb42f3 216 Pfam PF08281 Sigma-70, region 4 161 205 8.2E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_10635 4312e5dd144de57f5abb444f6beb42f3 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_10635 4312e5dd144de57f5abb444f6beb42f3 216 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 15 210 3.5E-113 T 12-10-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_10635 4312e5dd144de57f5abb444f6beb42f3 216 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 209 1.1E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_16475 6eb20dc67de4b783303955da3a0695a8 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 16 423 6.4E-153 T 12-10-2018 HW35_16475 6eb20dc67de4b783303955da3a0695a8 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 423 45.377 T 12-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16475 6eb20dc67de4b783303955da3a0695a8 428 SUPERFAMILY SSF51556 54 367 3.79E-110 T 12-10-2018 IPR032466 Metal-dependent hydrolase HW35_16475 6eb20dc67de4b783303955da3a0695a8 428 SUPERFAMILY SSF51338 1 424 5.91E-30 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_16475 6eb20dc67de4b783303955da3a0695a8 428 Gene3D G3DSA:3.20.20.140 54 366 1.1E-159 T 12-10-2018 HW35_16475 6eb20dc67de4b783303955da3a0695a8 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16475 6eb20dc67de4b783303955da3a0695a8 428 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16475 6eb20dc67de4b783303955da3a0695a8 428 Gene3D G3DSA:2.30.40.10 7 419 1.1E-159 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_16475 6eb20dc67de4b783303955da3a0695a8 428 Pfam PF01979 Amidohydrolase family 51 420 8.6E-49 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 HW35_01315 bd3281a7215c346aa3f96edde025dbda 404 Gene3D G3DSA:3.10.450.50 347 404 3.3E-10 T 12-10-2018 HW35_01315 bd3281a7215c346aa3f96edde025dbda 404 Pfam PF02810 SEC-C motif 386 404 5.0E-10 T 12-10-2018 IPR004027 SEC-C motif HW35_01315 bd3281a7215c346aa3f96edde025dbda 404 SUPERFAMILY SSF103642 383 403 1.54E-7 T 12-10-2018 HW35_04160 44af811a48bc397f583191c8e7edbec4 562 SUPERFAMILY SSF52540 168 518 3.22E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04160 44af811a48bc397f583191c8e7edbec4 562 SUPERFAMILY SSF52540 28 244 5.13E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04160 44af811a48bc397f583191c8e7edbec4 562 Pfam PF00176 SNF2 family N-terminal domain 79 326 1.8E-36 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 HW35_04160 44af811a48bc397f583191c8e7edbec4 562 SMART SM00487 56 234 9.3E-32 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_04160 44af811a48bc397f583191c8e7edbec4 562 SMART SM00490 386 466 5.2E-19 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_04160 44af811a48bc397f583191c8e7edbec4 562 Pfam PF00271 Helicase conserved C-terminal domain 360 466 2.0E-21 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_04160 44af811a48bc397f583191c8e7edbec4 562 Gene3D G3DSA:3.40.50.10810 57 284 1.7E-59 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily HW35_04160 44af811a48bc397f583191c8e7edbec4 562 Gene3D G3DSA:3.40.50.300 329 547 1.3E-46 T 12-10-2018 HW35_14615 da24a41a3f4418b146faebd550ac39cd 399 Gene3D G3DSA:2.30.40.10 15 390 2.2E-152 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_14615 da24a41a3f4418b146faebd550ac39cd 399 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 6 388 3.1E-125 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 HW35_14615 da24a41a3f4418b146faebd550ac39cd 399 SUPERFAMILY SSF51556 63 362 2.19E-104 T 12-10-2018 IPR032466 Metal-dependent hydrolase HW35_14615 da24a41a3f4418b146faebd550ac39cd 399 Pfam PF01979 Amidohydrolase family 59 390 1.2E-35 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 HW35_14615 da24a41a3f4418b146faebd550ac39cd 399 SUPERFAMILY SSF51338 8 395 1.1E-16 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_14615 da24a41a3f4418b146faebd550ac39cd 399 Gene3D G3DSA:3.20.20.140 63 362 2.2E-152 T 12-10-2018 HW35_14615 da24a41a3f4418b146faebd550ac39cd 399 PIRSF PIRSF038994 6 395 3.1E-140 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 HW35_00765 213fdfb05181b7c24c90ea95ec6f07e1 236 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 31 220 1.9E-22 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain HW35_00765 213fdfb05181b7c24c90ea95ec6f07e1 236 Gene3D G3DSA:3.40.50.1110 14 234 3.6E-36 T 12-10-2018 IPR036514 SGNH hydrolase superfamily HW35_00765 213fdfb05181b7c24c90ea95ec6f07e1 236 SUPERFAMILY SSF52266 25 231 2.82E-33 T 12-10-2018 HW35_15050 dddecca7d08e4571367a29369b78b131 313 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 86 230 6.1E-47 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HW35_15050 dddecca7d08e4571367a29369b78b131 313 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 86 230 3.7E-30 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HW35_15050 dddecca7d08e4571367a29369b78b131 313 Gene3D G3DSA:1.10.260.150 65 313 5.2E-79 T 12-10-2018 HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 SUPERFAMILY SSF52540 91 369 8.35E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 SUPERFAMILY SSF68912 4 48 9.42E-11 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 Gene3D G3DSA:1.10.720.10 1 47 4.3E-20 T 12-10-2018 HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 Gene3D G3DSA:3.40.50.300 131 413 7.2E-123 T 12-10-2018 HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 SMART SM00959 7 49 1.9E-16 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 415 222.168 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 SUPERFAMILY SSF50249 51 114 3.43E-7 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 Pfam PF07497 Rho termination factor, RNA-binding domain 53 126 1.4E-31 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 Pfam PF07498 Rho termination factor, N-terminal domain 8 49 6.1E-16 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 157 361 6.5E-17 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 412 1.3E-204 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 Gene3D G3DSA:2.40.50.140 48 124 9.2E-30 T 12-10-2018 HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 SMART SM00382 168 353 9.4E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_09210 4e1d902d299e9c4d73c198672e80751b 421 SMART SM00357 54 119 1.1E-19 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 HW35_08510 d0ac5e3bcad7c74def02e3a5282b56c6 73 Pfam PF11148 Protein of unknown function (DUF2922) 3 68 7.3E-24 T 12-10-2018 IPR021321 Protein of unknown function DUF2922 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 632 648 6.2E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 604 620 6.2E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 664 689 6.2E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 488 506 6.2E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 SUPERFAMILY SSF56784 322 736 1.37E-65 T 12-10-2018 IPR036412 HAD-like superfamily HW35_16515 947d2f33dde45b146ab74122ff232afe 892 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 600 722 7.5E-38 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 428 578 3.3E-18 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 209 345 5.6E-29 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 176 1.3E-18 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 SMART SM00831 2 76 5.5E-28 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 SUPERFAMILY SSF81660 332 534 2.4E-57 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 54 882 1.1E-213 T 12-10-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 SUPERFAMILY SSF81653 114 223 1.96E-30 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 651 1.2E-41 T 12-10-2018 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 541 1.2E-41 T 12-10-2018 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 562 1.2E-41 T 12-10-2018 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 668 1.2E-41 T 12-10-2018 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 1.2E-41 T 12-10-2018 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 1.2E-41 T 12-10-2018 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 Pfam PF00702 haloacid dehalogenase-like hydrolase 322 646 4.2E-26 T 12-10-2018 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 Pfam PF00689 Cation transporting ATPase, C-terminus 716 881 3.4E-51 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 SUPERFAMILY SSF81665 1 881 1.18E-135 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 Gene3D G3DSA:3.40.50.1000 321 677 0.0 T 12-10-2018 IPR023214 HAD superfamily HW35_16515 947d2f33dde45b146ab74122ff232afe 892 Gene3D G3DSA:2.70.150.10 15 227 0.0 T 12-10-2018 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 Gene3D G3DSA:1.20.1110.10 54 877 0.0 T 12-10-2018 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 Gene3D G3DSA:3.40.1110.10 334 537 0.0 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 71 2.6E-21 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 HW35_16515 947d2f33dde45b146ab74122ff232afe 892 Pfam PF00122 E1-E2 ATPase 110 304 1.1E-56 T 12-10-2018 HW35_08095 3f19537e4bb80b75bf044e4c8588931f 380 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 33 365 6.1E-119 T 12-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 HW35_08095 3f19537e4bb80b75bf044e4c8588931f 380 Gene3D G3DSA:3.40.50.2000 192 352 1.5E-157 T 12-10-2018 HW35_08095 3f19537e4bb80b75bf044e4c8588931f 380 SUPERFAMILY SSF53756 5 369 5.93E-137 T 12-10-2018 HW35_08095 3f19537e4bb80b75bf044e4c8588931f 380 Gene3D G3DSA:3.40.50.2000 7 363 1.5E-157 T 12-10-2018 HW35_08095 3f19537e4bb80b75bf044e4c8588931f 380 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 368 4.7E-167 T 12-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 HW35_03130 0ad61026bf9ad622acd3f2ad80383c0b 100 Gene3D G3DSA:1.10.10.60 12 92 6.9E-5 T 12-10-2018 HW35_03130 0ad61026bf9ad622acd3f2ad80383c0b 100 Pfam PF13518 Helix-turn-helix domain 16 63 2.3E-7 T 12-10-2018 HW35_03130 0ad61026bf9ad622acd3f2ad80383c0b 100 SUPERFAMILY SSF46689 8 90 1.58E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_11300 265471032133e0f6e0812b6f0c6a28e1 702 SUPERFAMILY SSF82866 123 349 2.88E-32 T 12-10-2018 HW35_11300 265471032133e0f6e0812b6f0c6a28e1 702 Gene3D G3DSA:3.30.70.1440 495 534 2.3E-8 T 12-10-2018 HW35_11300 265471032133e0f6e0812b6f0c6a28e1 702 Gene3D G3DSA:1.20.1640.10 535 633 2.3E-8 T 12-10-2018 HW35_11300 265471032133e0f6e0812b6f0c6a28e1 702 Gene3D G3DSA:1.20.1640.10 145 348 3.7E-10 T 12-10-2018 HW35_11300 265471032133e0f6e0812b6f0c6a28e1 702 SUPERFAMILY SSF82866 514 696 9.55E-27 T 12-10-2018 HW35_11300 265471032133e0f6e0812b6f0c6a28e1 702 Pfam PF03176 MMPL family 413 693 2.3E-44 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 HW35_11300 265471032133e0f6e0812b6f0c6a28e1 702 Pfam PF03176 MMPL family 50 377 1.1E-65 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 Pfam PF13426 PAS domain 38 136 7.1E-7 T 12-10-2018 IPR000014 PAS domain HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 Pfam PF00989 PAS fold 156 258 3.0E-12 T 12-10-2018 IPR013767 PAS fold GO:0006355 HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 SUPERFAMILY SSF55785 36 142 3.84E-19 T 12-10-2018 IPR035965 PAS domain superfamily HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 SMART SM00091 153 219 5.9E-7 T 12-10-2018 IPR000014 PAS domain HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 SMART SM00091 25 91 0.002 T 12-10-2018 IPR000014 PAS domain HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 SMART SM00388 280 343 1.9E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 SMART SM00086 96 137 0.003 T 12-10-2018 IPR001610 PAC motif HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 SMART SM00086 225 265 0.74 T 12-10-2018 IPR001610 PAC motif HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 SUPERFAMILY SSF47384 275 341 1.47E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 Pfam PF00512 His Kinase A (phospho-acceptor) domain 282 341 5.8E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 SUPERFAMILY SSF55785 140 263 2.09E-19 T 12-10-2018 IPR035965 PAS domain superfamily HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 27 143 4.8E-17 T 12-10-2018 IPR000014 PAS domain HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 149 272 1.0E-18 T 12-10-2018 IPR000014 PAS domain HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 Gene3D G3DSA:3.30.450.20 140 263 1.0E-20 T 12-10-2018 HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 Gene3D G3DSA:3.30.450.20 21 139 2.8E-18 T 12-10-2018 HW35_17450 20b5138f9aa0d53c98432c9b1039bbe1 345 Gene3D G3DSA:1.10.287.130 265 341 4.1E-15 T 12-10-2018 HW35_09685 982f9e6dfab3af524fc3ac209af1af28 219 Pfam PF01965 DJ-1/PfpI family 26 216 1.8E-18 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 HW35_09685 982f9e6dfab3af524fc3ac209af1af28 219 Gene3D G3DSA:3.40.50.880 1 219 4.6E-79 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_09685 982f9e6dfab3af524fc3ac209af1af28 219 SUPERFAMILY SSF52317 1 218 3.64E-67 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 Gene3D G3DSA:3.20.20.100 1 276 7.7E-130 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 PRINTS PR00069 Aldo-keto reductase signature 160 189 8.4E-55 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 PRINTS PR00069 Aldo-keto reductase signature 126 143 8.4E-55 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 PRINTS PR00069 Aldo-keto reductase signature 197 221 8.4E-55 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 PRINTS PR00069 Aldo-keto reductase signature 40 64 8.4E-55 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 PRINTS PR00069 Aldo-keto reductase signature 96 114 8.4E-55 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 Pfam PF00248 Aldo/keto reductase family 27 262 8.0E-58 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 44 61 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 PIRSF PIRSF000097 3 119 2.3E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 PIRSF PIRSF000097 115 274 5.9E-56 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_17515 32d9bcb2ae599b01ea8749ba27730c73 280 SUPERFAMILY SSF51430 7 269 7.99E-99 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily HW35_00720 1fc033a6705b60ba71a7fda90227b934 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 5.5E-92 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HW35_00720 1fc033a6705b60ba71a7fda90227b934 455 PIRSF PIRSF006603 1 453 6.9E-65 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HW35_00720 1fc033a6705b60ba71a7fda90227b934 455 Pfam PF01554 MatE 247 407 5.6E-32 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HW35_00720 1fc033a6705b60ba71a7fda90227b934 455 Pfam PF01554 MatE 20 180 5.0E-30 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HW35_09400 2cc96b7ab23db743b0ffcb795155f293 247 Hamap MF_01442 Putative heme-dependent peroxidase . 1 247 57.979 T 12-10-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family HW35_09400 2cc96b7ab23db743b0ffcb795155f293 247 Pfam PF06778 Chlorite dismutase 33 235 5.6E-78 T 12-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase HW35_09400 2cc96b7ab23db743b0ffcb795155f293 247 SUPERFAMILY SSF54909 1 246 3.49E-96 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel HW35_09400 2cc96b7ab23db743b0ffcb795155f293 247 Gene3D G3DSA:3.30.70.1030 1 136 2.5E-56 T 12-10-2018 HW35_09400 2cc96b7ab23db743b0ffcb795155f293 247 Gene3D G3DSA:3.30.70.1100 137 247 4.1E-49 T 12-10-2018 HW35_00840 3293ea5e9bf3479a18d1f074fb01ea8f 225 SUPERFAMILY SSF143081 2 217 5.49E-74 T 12-10-2018 IPR036590 SOS response associated peptidase-like HW35_00840 3293ea5e9bf3479a18d1f074fb01ea8f 225 Pfam PF02586 SOS response associated peptidase (SRAP) 1 212 4.8E-69 T 12-10-2018 IPR003738 SOS response associated peptidase (SRAP) HW35_00840 3293ea5e9bf3479a18d1f074fb01ea8f 225 Gene3D G3DSA:3.90.1680.10 1 224 2.2E-73 T 12-10-2018 IPR036590 SOS response associated peptidase-like HW35_06215 0da1be9205243c39162aecfea5d4fe1e 331 Gene3D G3DSA:3.90.180.10 8 325 8.8E-101 T 12-10-2018 HW35_06215 0da1be9205243c39162aecfea5d4fe1e 331 SUPERFAMILY SSF50129 1 150 4.11E-38 T 12-10-2018 IPR011032 GroES-like superfamily HW35_06215 0da1be9205243c39162aecfea5d4fe1e 331 SMART SM00829 10 327 1.1E-62 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HW35_06215 0da1be9205243c39162aecfea5d4fe1e 331 Pfam PF13602 Zinc-binding dehydrogenase 189 327 2.6E-27 T 12-10-2018 HW35_06215 0da1be9205243c39162aecfea5d4fe1e 331 Gene3D G3DSA:3.40.50.720 126 296 8.8E-101 T 12-10-2018 HW35_06215 0da1be9205243c39162aecfea5d4fe1e 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 2.3E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HW35_06215 0da1be9205243c39162aecfea5d4fe1e 331 SUPERFAMILY SSF51735 118 294 7.34E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_00415 3bf80ce118516cc5ab958c2dce2795c8 161 SUPERFAMILY SSF140566 3 135 3.53E-16 T 12-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 HW35_00415 3bf80ce118516cc5ab958c2dce2795c8 161 Gene3D G3DSA:1.20.58.300 3 135 2.3E-9 T 12-10-2018 HW35_00415 3bf80ce118516cc5ab958c2dce2795c8 161 Pfam PF05130 FlgN protein 2 149 6.3E-23 T 12-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 HW35_15110 978b3da06925351299972cf450cf86d3 187 ProDom PD106196 YISN IG BH1722 5 178 2.0E-34 T 12-10-2018 IPR024488 Protein of unknown function DUF2777 HW35_15110 978b3da06925351299972cf450cf86d3 187 Pfam PF10949 Protein of unknown function (DUF2777) 4 183 7.1E-70 T 12-10-2018 IPR024488 Protein of unknown function DUF2777 HW35_09370 8c999b458fb61b5b99e1bd258b4a690e 274 Pfam PF03099 Biotin/lipoate A/B protein ligase family 73 181 2.8E-13 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 HW35_09370 8c999b458fb61b5b99e1bd258b4a690e 274 Gene3D G3DSA:3.30.930.10 4 274 2.1E-76 T 12-10-2018 HW35_09370 8c999b458fb61b5b99e1bd258b4a690e 274 SUPERFAMILY SSF55681 5 257 1.08E-68 T 12-10-2018 HW35_09370 8c999b458fb61b5b99e1bd258b4a690e 274 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 3 274 48.053 T 12-10-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 MetaCyc: PWY-6987 HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 SUPERFAMILY SSF52540 1 1164 4.61E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 638 1.0E-31 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 Gene3D G3DSA:3.30.70.1620 579 668 1.9E-66 T 12-10-2018 HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 Gene3D G3DSA:1.20.1060.20 495 680 1.9E-66 T 12-10-2018 HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 SUPERFAMILY SSF75553 483 687 1.7E-56 T 12-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 SMART SM00968 519 638 2.3E-41 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1179 0.0 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 Gene3D G3DSA:3.40.50.300 1 246 1.4E-60 T 12-10-2018 HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 Gene3D G3DSA:3.40.50.300 926 1188 6.6E-56 T 12-10-2018 HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1181 24.739 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1172 2.5E-66 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal HW35_16660 a1019e3f17a5e8e4e44e9259dbb991a2 1188 PIRSF PIRSF005719 1 1187 0.0 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein HW35_06620 32d19985ac73af8632593d1d1f250989 486 PIRSF PIRSF036492 31 482 2.3E-88 T 12-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 HW35_06620 32d19985ac73af8632593d1d1f250989 486 Gene3D G3DSA:3.40.309.10 258 448 6.0E-187 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 HW35_06620 32d19985ac73af8632593d1d1f250989 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 HW35_06620 32d19985ac73af8632593d1d1f250989 486 SUPERFAMILY SSF53720 8 482 5.89E-177 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HW35_06620 32d19985ac73af8632593d1d1f250989 486 Gene3D G3DSA:3.40.605.10 29 477 6.0E-187 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_06620 32d19985ac73af8632593d1d1f250989 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 HW35_06620 32d19985ac73af8632593d1d1f250989 486 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 31 477 2.6E-201 T 12-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 HW35_06620 32d19985ac73af8632593d1d1f250989 486 Pfam PF00171 Aldehyde dehydrogenase family 19 478 3.3E-179 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 HW35_17675 76224e042fd5cc444876df34caf5abf8 333 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 314 1.1E-70 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HW35_17675 76224e042fd5cc444876df34caf5abf8 333 Gene3D G3DSA:3.40.50.1100 59 155 3.4E-105 T 12-10-2018 HW35_17675 76224e042fd5cc444876df34caf5abf8 333 Gene3D G3DSA:3.40.50.1100 17 319 3.4E-105 T 12-10-2018 HW35_17675 76224e042fd5cc444876df34caf5abf8 333 SUPERFAMILY SSF53686 12 322 2.36E-85 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HW35_10590 0bc2075763536c7aab39458652083034 362 SUPERFAMILY SSF88723 164 290 2.69E-25 T 12-10-2018 IPR029060 PIN-like domain superfamily HW35_10590 0bc2075763536c7aab39458652083034 362 SMART SM00670 162 269 7.1E-14 T 12-10-2018 IPR002716 PIN domain HW35_10590 0bc2075763536c7aab39458652083034 362 Gene3D G3DSA:3.40.50.1010 159 293 1.0E-54 T 12-10-2018 HW35_03270 44321292bb1b21fa2f8d22c0f9ad2e5c 254 TIGRFAM TIGR02878 spore_ypjB: sporulation protein YpjB 18 247 9.6E-82 T 12-10-2018 IPR014231 Sporulation protein YpjB HW35_03270 44321292bb1b21fa2f8d22c0f9ad2e5c 254 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 18 246 6.0E-89 T 12-10-2018 IPR014231 Sporulation protein YpjB HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 SUPERFAMILY SSF50447 205 302 7.86E-32 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 1.8E-14 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 Gene3D G3DSA:3.40.50.300 1 203 4.0E-71 T 12-10-2018 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 SUPERFAMILY SSF52540 9 226 1.09E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 Gene3D G3DSA:2.40.30.10 339 394 2.1E-25 T 12-10-2018 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 60.852 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 6.0E-61 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.9E-232 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 1.2E-32 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 SUPERFAMILY SSF50465 303 395 8.35E-35 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 1.2E-18 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HW35_10705 4d018d641c7bf550ecd3d135f9742423 395 Gene3D G3DSA:2.40.30.10 206 335 9.4E-55 T 12-10-2018 HW35_05405 de964c0339d38f7d4108b911fd5aaade 199 SUPERFAMILY SSF63817 64 195 3.14E-35 T 12-10-2018 IPR023365 Sortase domain superfamily HW35_05405 de964c0339d38f7d4108b911fd5aaade 199 TIGRFAM TIGR01076 sortase_fam: sortase 71 193 1.8E-36 T 12-10-2018 IPR005754 Sortase family HW35_05405 de964c0339d38f7d4108b911fd5aaade 199 Pfam PF04203 Sortase family 74 194 2.9E-28 T 12-10-2018 IPR005754 Sortase family HW35_05405 de964c0339d38f7d4108b911fd5aaade 199 Gene3D G3DSA:2.40.260.10 23 198 3.3E-40 T 12-10-2018 IPR023365 Sortase domain superfamily HW35_03190 344854245f30ef1c4e9611c4f249b5f0 157 Gene3D G3DSA:3.10.450.40 23 93 6.8E-18 T 12-10-2018 HW35_03190 344854245f30ef1c4e9611c4f249b5f0 157 Gene3D G3DSA:3.10.450.40 94 155 4.4E-20 T 12-10-2018 HW35_03190 344854245f30ef1c4e9611c4f249b5f0 157 SUPERFAMILY SSF54403 33 94 7.48E-17 T 12-10-2018 HW35_03190 344854245f30ef1c4e9611c4f249b5f0 157 SUPERFAMILY SSF54403 94 156 4.42E-17 T 12-10-2018 HW35_10715 86a92e4de08b57f91bd96e78117df8a2 208 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 39.709 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10715 86a92e4de08b57f91bd96e78117df8a2 208 Gene3D G3DSA:2.40.30.10 133 208 4.0E-17 T 12-10-2018 HW35_10715 86a92e4de08b57f91bd96e78117df8a2 208 Pfam PF00297 Ribosomal protein L3 100 180 4.3E-16 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10715 86a92e4de08b57f91bd96e78117df8a2 208 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 3.2E-88 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10715 86a92e4de08b57f91bd96e78117df8a2 208 SUPERFAMILY SSF50447 1 207 8.83E-83 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HW35_10715 86a92e4de08b57f91bd96e78117df8a2 208 Gene3D G3DSA:2.40.50.620 33 96 2.3E-17 T 12-10-2018 HW35_10715 86a92e4de08b57f91bd96e78117df8a2 208 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site HW35_07025 1f371d26468b6a227075d886e9e1ee11 273 Pfam PF01925 Sulfite exporter TauE/SafE 7 266 1.3E-55 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HW35_13210 f65a866320deaae5fe1521c0a960fbde 347 Pfam PF03576 Peptidase family S58 19 332 4.4E-107 T 12-10-2018 IPR005321 Peptidase S58, DmpA HW35_13210 f65a866320deaae5fe1521c0a960fbde 347 SUPERFAMILY SSF56266 2 330 7.06E-98 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HW35_13210 f65a866320deaae5fe1521c0a960fbde 347 Gene3D G3DSA:3.60.70.12 1 342 8.0E-128 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HW35_12275 087732494fb9f3b54a6ee52b4108101d 334 Gene3D G3DSA:3.30.565.10 174 323 8.8E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_12275 087732494fb9f3b54a6ee52b4108101d 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 325 2.3E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_12275 087732494fb9f3b54a6ee52b4108101d 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 280 2.0E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_12275 087732494fb9f3b54a6ee52b4108101d 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 304 2.0E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_12275 087732494fb9f3b54a6ee52b4108101d 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 252 266 2.0E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_12275 087732494fb9f3b54a6ee52b4108101d 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 323 2.0E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_12275 087732494fb9f3b54a6ee52b4108101d 334 SMART SM00387 216 326 1.2E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_12275 087732494fb9f3b54a6ee52b4108101d 334 SUPERFAMILY SSF55874 175 323 5.24E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_12275 087732494fb9f3b54a6ee52b4108101d 334 Gene3D G3DSA:1.10.287.130 124 169 8.8E-33 T 12-10-2018 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 Gene3D G3DSA:1.25.40.10 2 178 7.9E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 SUPERFAMILY SSF48452 224 403 2.69E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 Gene3D G3DSA:1.25.40.10 179 405 9.4E-39 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 Pfam PF13181 Tetratricopeptide repeat 263 293 0.0043 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 SMART SM00028 182 215 250.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 SMART SM00028 222 255 330.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 SMART SM00028 300 333 51.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 SMART SM00028 262 295 2.2E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 Pfam PF01381 Helix-turn-helix 7 59 2.5E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 SUPERFAMILY SSF47413 1 60 1.94E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 SUPERFAMILY SSF48452 148 250 9.01E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_06715 1c5c99cf049e897617d7b81475ab7835 405 SMART SM00530 6 60 4.3E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_14230 e619cba45f1ece2ae1a86f2ac8ad8871 88 Pfam PF14043 WVELL protein 4 76 1.3E-38 T 12-10-2018 IPR026952 WVELL protein HW35_00195 4246d6ad0822dafd5b7127960377eaa0 245 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 3 59 3.2E-19 T 12-10-2018 IPR025713 Motility protein B, N-terminal domain HW35_00195 4246d6ad0822dafd5b7127960377eaa0 245 Gene3D G3DSA:3.30.1330.60 69 245 5.0E-50 T 12-10-2018 IPR036737 OmpA-like domain superfamily HW35_00195 4246d6ad0822dafd5b7127960377eaa0 245 SUPERFAMILY SSF103088 124 238 2.62E-32 T 12-10-2018 IPR036737 OmpA-like domain superfamily HW35_00195 4246d6ad0822dafd5b7127960377eaa0 245 Pfam PF00691 OmpA family 134 232 8.1E-21 T 12-10-2018 IPR006665 OmpA-like domain HW35_02465 064371b95115dffe9ccd969483ee2942 200 SUPERFAMILY SSF52833 35 189 4.49E-35 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_02465 064371b95115dffe9ccd969483ee2942 200 Pfam PF02630 SCO1/SenC 28 180 5.5E-25 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_02465 064371b95115dffe9ccd969483ee2942 200 Gene3D G3DSA:3.40.30.10 26 200 7.1E-43 T 12-10-2018 HW35_03450 8c219cf43b11922de0636f032f939e24 247 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 31 247 1.4E-100 T 12-10-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 HW35_03450 8c219cf43b11922de0636f032f939e24 247 Pfam PF07486 Cell Wall Hydrolase 148 246 1.8E-28 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 HW35_03450 8c219cf43b11922de0636f032f939e24 247 Gene3D G3DSA:1.10.10.2520 132 211 3.7E-32 T 12-10-2018 HW35_03450 8c219cf43b11922de0636f032f939e24 247 Pfam PF01471 Putative peptidoglycan binding domain 43 98 1.4E-16 T 12-10-2018 IPR002477 Peptidoglycan binding-like HW35_03450 8c219cf43b11922de0636f032f939e24 247 SUPERFAMILY SSF47090 33 99 4.08E-20 T 12-10-2018 IPR036365 PGBD-like superfamily HW35_03450 8c219cf43b11922de0636f032f939e24 247 Gene3D G3DSA:1.10.101.10 27 109 2.3E-21 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 HW35_03450 8c219cf43b11922de0636f032f939e24 247 Gene3D G3DSA:2.40.10.420 212 247 1.2E-22 T 12-10-2018 HW35_09110 d6c756926d8b3d0b6158ad0b2f13107b 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 16.389 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09110 d6c756926d8b3d0b6158ad0b2f13107b 70 SUPERFAMILY SSF81333 3 67 6.93E-20 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily HW35_09110 d6c756926d8b3d0b6158ad0b2f13107b 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 5.4E-20 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09110 d6c756926d8b3d0b6158ad0b2f13107b 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 5.4E-20 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09110 d6c756926d8b3d0b6158ad0b2f13107b 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 5.4E-20 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09110 d6c756926d8b3d0b6158ad0b2f13107b 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 13 67 1.0E-24 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HW35_09110 d6c756926d8b3d0b6158ad0b2f13107b 70 Gene3D G3DSA:1.20.20.10 1 70 8.3E-30 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09110 d6c756926d8b3d0b6158ad0b2f13107b 70 Pfam PF00137 ATP synthase subunit C 4 66 2.6E-15 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HW35_09110 d6c756926d8b3d0b6158ad0b2f13107b 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 PIRSF PIRSF000097 122 279 6.9E-52 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 PIRSF PIRSF000097 4 127 3.3E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 132 149 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 SUPERFAMILY SSF51430 8 277 5.5E-97 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 46 63 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 PRINTS PR00069 Aldo-keto reductase signature 166 195 4.4E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 PRINTS PR00069 Aldo-keto reductase signature 42 66 4.4E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 PRINTS PR00069 Aldo-keto reductase signature 102 120 4.4E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 PRINTS PR00069 Aldo-keto reductase signature 132 149 4.4E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 PRINTS PR00069 Aldo-keto reductase signature 203 227 4.4E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 Pfam PF00248 Aldo/keto reductase family 33 268 5.7E-51 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 236 251 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HW35_01610 18cd373f5b986d6701f761e4911e85b9 282 Gene3D G3DSA:3.20.20.100 3 282 1.7E-128 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily HW35_10210 98ca8b85c47707eaee0a088169c20ab0 393 Pfam PF03990 Domain of unknown function (DUF348) 40 80 3.9E-9 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 HW35_10210 98ca8b85c47707eaee0a088169c20ab0 393 Pfam PF03990 Domain of unknown function (DUF348) 156 193 4.4E-11 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 HW35_10210 98ca8b85c47707eaee0a088169c20ab0 393 Pfam PF03990 Domain of unknown function (DUF348) 97 135 6.0E-12 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 HW35_10210 98ca8b85c47707eaee0a088169c20ab0 393 Pfam PF06725 3D domain 333 393 7.5E-23 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 HW35_10210 98ca8b85c47707eaee0a088169c20ab0 393 Gene3D G3DSA:2.40.40.10 316 383 1.5E-5 T 12-10-2018 IPR036908 RlpA-like domain superfamily HW35_10210 98ca8b85c47707eaee0a088169c20ab0 393 SMART SM01208 207 285 2.7E-27 T 12-10-2018 IPR011098 G5 domain HW35_10210 98ca8b85c47707eaee0a088169c20ab0 393 SUPERFAMILY SSF50685 334 382 2.23E-9 T 12-10-2018 IPR036908 RlpA-like domain superfamily HW35_10210 98ca8b85c47707eaee0a088169c20ab0 393 Gene3D G3DSA:2.20.230.10 163 284 6.4E-21 T 12-10-2018 HW35_10210 98ca8b85c47707eaee0a088169c20ab0 393 Pfam PF07501 G5 domain 212 284 3.9E-21 T 12-10-2018 IPR011098 G5 domain HW35_05900 fa27f766ff3ee6447dd1c3c7463bdee5 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_05900 fa27f766ff3ee6447dd1c3c7463bdee5 572 Gene3D G3DSA:3.40.50.12780 15 455 7.7E-120 T 12-10-2018 HW35_05900 fa27f766ff3ee6447dd1c3c7463bdee5 572 Gene3D G3DSA:3.30.300.30 458 571 3.2E-28 T 12-10-2018 HW35_05900 fa27f766ff3ee6447dd1c3c7463bdee5 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 549 9.2E-26 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_05900 fa27f766ff3ee6447dd1c3c7463bdee5 572 SUPERFAMILY SSF56801 16 562 1.7E-160 T 12-10-2018 HW35_05900 fa27f766ff3ee6447dd1c3c7463bdee5 572 Pfam PF00501 AMP-binding enzyme 51 462 5.6E-91 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_03970 08b899735c30c5462744329a7295c207 452 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 4 442 30.125 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 HW35_03970 08b899735c30c5462744329a7295c207 452 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 8 356 5.1E-140 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 HW35_03970 08b899735c30c5462744329a7295c207 452 Pfam PF13742 OB-fold nucleic acid binding domain 7 102 5.9E-31 T 12-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 HW35_03970 08b899735c30c5462744329a7295c207 452 Pfam PF02601 Exonuclease VII, large subunit 125 437 4.4E-103 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 HW35_00130 2bef0ef9843f53a43c29eed892cb5cbe 144 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 44 142 9.0E-9 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 HW35_00130 2bef0ef9843f53a43c29eed892cb5cbe 144 SUPERFAMILY SSF52540 2 144 6.37E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_00130 2bef0ef9843f53a43c29eed892cb5cbe 144 Gene3D G3DSA:3.40.50.300 33 144 2.5E-8 T 12-10-2018 HW35_00685 240642e1aaa750c900569870a310adde 436 SUPERFAMILY SSF53187 10 425 6.86E-64 T 12-10-2018 HW35_00685 240642e1aaa750c900569870a310adde 436 Pfam PF01546 Peptidase family M20/M25/M40 90 421 1.7E-31 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 HW35_00685 240642e1aaa750c900569870a310adde 436 Gene3D G3DSA:3.30.70.360 195 337 8.9E-95 T 12-10-2018 HW35_00685 240642e1aaa750c900569870a310adde 436 Pfam PF07687 Peptidase dimerisation domain 192 313 2.6E-26 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain HW35_00685 240642e1aaa750c900569870a310adde 436 SUPERFAMILY SSF55031 219 311 1.05E-8 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain HW35_00685 240642e1aaa750c900569870a310adde 436 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 24 415 1.3E-115 T 12-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase HW35_00685 240642e1aaa750c900569870a310adde 436 Gene3D G3DSA:3.40.630.10 41 424 8.9E-95 T 12-10-2018 HW35_10280 983b4067c6972a872fba5ba1ee6a6a48 76 ProDom PD057826 YABK 4 75 3.0E-25 T 12-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 HW35_10280 983b4067c6972a872fba5ba1ee6a6a48 76 Pfam PF10955 Protein of unknown function (DUF2757) 1 76 3.6E-36 T 12-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 HW35_06970 836b25d7b12703181bc4c7271b4c9037 166 Gene3D G3DSA:1.10.3760.10 2 166 1.2E-76 T 12-10-2018 HW35_06970 836b25d7b12703181bc4c7271b4c9037 166 SUPERFAMILY SSF101307 10 161 3.27E-55 T 12-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 HW35_06970 836b25d7b12703181bc4c7271b4c9037 166 PIRSF PIRSF019587 5 166 4.5E-78 T 12-10-2018 IPR026038 Putative phosphatidylglycerophosphatase HW35_06970 836b25d7b12703181bc4c7271b4c9037 166 Pfam PF04608 Phosphatidylglycerophosphatase A 23 159 5.1E-19 T 12-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 HW35_12590 18281ea7fab1190e23bef8ec33857835 309 Gene3D G3DSA:3.40.50.1820 12 307 1.2E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_12590 18281ea7fab1190e23bef8ec33857835 309 SUPERFAMILY SSF53474 13 305 1.01E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_12590 18281ea7fab1190e23bef8ec33857835 309 Pfam PF12146 Serine aminopeptidase, S33 53 272 1.3E-16 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 HW35_12590 18281ea7fab1190e23bef8ec33857835 309 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 97 127 - T 12-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Gene3D G3DSA:1.10.288.10 898 956 3.2E-64 T 12-10-2018 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 SUPERFAMILY SSF56507 870 1147 3.53E-89 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 SUPERFAMILY SSF47644 620 706 7.32E-25 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 PIRSF PIRSF000381 1 1149 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Gene3D G3DSA:3.10.196.10 885 1147 3.2E-64 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Pfam PF02607 B12 binding domain 627 700 1.2E-21 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Gene3D G3DSA:3.40.50.280 710 857 1.5E-48 T 12-10-2018 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 SUPERFAMILY SSF51717 337 599 2.09E-82 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Pfam PF02574 Homocysteine S-methyltransferase 15 304 9.9E-74 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Pfam PF00809 Pterin binding enzyme 340 573 3.4E-39 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 TIGRFAM TIGR02082 metH: methionine synthase 10 1147 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Gene3D G3DSA:3.20.20.20 320 617 1.0E-104 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 SUPERFAMILY SSF52242 711 852 3.14E-41 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 900 1148 1.0E-55 T 12-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 SUPERFAMILY SSF82282 4 379 4.32E-114 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 SMART SM01018 624 707 1.7E-38 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Pfam PF02310 B12 binding domain 714 804 2.1E-20 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Gene3D G3DSA:3.20.20.330 4 319 3.2E-109 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 HW35_06670 aa3d1187a0d3a5132c38605774c3f914 1149 Gene3D G3DSA:1.10.1240.10 618 704 6.6E-28 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_10185 ca291e9bf3768d50c7386123b9e6b89c 291 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 12-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 HW35_10185 ca291e9bf3768d50c7386123b9e6b89c 291 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 214 8.1E-28 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 HW35_10185 ca291e9bf3768d50c7386123b9e6b89c 291 PIRSF PIRSF005917 3 290 8.7E-106 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 HW35_10185 ca291e9bf3768d50c7386123b9e6b89c 291 Gene3D G3DSA:3.30.950.10 123 237 1.1E-41 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 HW35_10185 ca291e9bf3768d50c7386123b9e6b89c 291 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 15 288 6.8E-84 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 HW35_10185 ca291e9bf3768d50c7386123b9e6b89c 291 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 233 37.42 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 HW35_10185 ca291e9bf3768d50c7386123b9e6b89c 291 SUPERFAMILY SSF53790 13 231 2.88E-83 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 HW35_10185 ca291e9bf3768d50c7386123b9e6b89c 291 Gene3D G3DSA:3.40.1010.10 2 122 4.2E-48 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 HW35_15695 a0164a0a10b331eaa1d1359e17fd57dc 209 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 203 98.615 T 12-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 HW35_15695 a0164a0a10b331eaa1d1359e17fd57dc 209 Gene3D G3DSA:3.40.225.10 3 203 2.9E-46 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily HW35_15695 a0164a0a10b331eaa1d1359e17fd57dc 209 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 195 3.6E-37 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal HW35_15695 a0164a0a10b331eaa1d1359e17fd57dc 209 SUPERFAMILY SSF53639 1 202 3.14E-41 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily HW35_15695 a0164a0a10b331eaa1d1359e17fd57dc 209 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 9 198 8.3E-62 T 12-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 HW35_15695 a0164a0a10b331eaa1d1359e17fd57dc 209 SMART SM01007 7 195 3.1E-33 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal HW35_14040 0108655a1954ed1294f1af48260945eb 372 SUPERFAMILY SSF51905 2 366 4.92E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_14040 0108655a1954ed1294f1af48260945eb 372 Gene3D G3DSA:3.30.9.10 88 311 4.6E-82 T 12-10-2018 HW35_14040 0108655a1954ed1294f1af48260945eb 372 Gene3D G3DSA:3.50.50.60 5 351 4.6E-82 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_14040 0108655a1954ed1294f1af48260945eb 372 Pfam PF01266 FAD dependent oxidoreductase 3 351 3.2E-56 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HW35_14040 0108655a1954ed1294f1af48260945eb 372 SUPERFAMILY SSF54373 222 311 4.05E-16 T 12-10-2018 HW35_15970 586d5ee7fa6b1c478969dd53c1672c2a 319 SUPERFAMILY SSF51412 2 315 1.5E-69 T 12-10-2018 HW35_15970 586d5ee7fa6b1c478969dd53c1672c2a 319 Gene3D G3DSA:3.20.20.70 2 318 6.9E-109 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_15970 586d5ee7fa6b1c478969dd53c1672c2a 319 Pfam PF03060 Nitronate monooxygenase 5 308 5.3E-68 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 HW35_08115 aee154457520ba252ed87f360f638f16 408 Gene3D G3DSA:3.40.50.1100 112 208 1.0E-104 T 12-10-2018 HW35_08115 aee154457520ba252ed87f360f638f16 408 Gene3D G3DSA:3.40.50.1100 61 387 1.0E-104 T 12-10-2018 HW35_08115 aee154457520ba252ed87f360f638f16 408 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 381 4.6E-62 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HW35_08115 aee154457520ba252ed87f360f638f16 408 SUPERFAMILY SSF53686 5 391 1.7E-88 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HW35_11330 91deb17d2c93939c329a2955e38f2303 187 SUPERFAMILY SSF46689 3 77 5.34E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_11330 91deb17d2c93939c329a2955e38f2303 187 Gene3D G3DSA:1.10.357.10 52 186 6.6E-18 T 12-10-2018 HW35_11330 91deb17d2c93939c329a2955e38f2303 187 SUPERFAMILY SSF48498 77 186 2.0E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily HW35_11330 91deb17d2c93939c329a2955e38f2303 187 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 51 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HW35_11330 91deb17d2c93939c329a2955e38f2303 187 Gene3D G3DSA:1.10.10.60 1 51 2.9E-17 T 12-10-2018 HW35_11330 91deb17d2c93939c329a2955e38f2303 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 7.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_11330 91deb17d2c93939c329a2955e38f2303 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 7.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_11330 91deb17d2c93939c329a2955e38f2303 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 7.7E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_06170 9e98216c84a833cae4893454e0516d7c 80 Gene3D G3DSA:2.40.240.20 1 77 3.8E-34 T 12-10-2018 HW35_06170 9e98216c84a833cae4893454e0516d7c 80 Pfam PF10763 Protein of unknown function (DUF2584) 1 80 5.1E-37 T 12-10-2018 IPR019699 Protein of unknown function DUF2584 HW35_06170 9e98216c84a833cae4893454e0516d7c 80 SUPERFAMILY SSF88697 1 80 1.19E-29 T 12-10-2018 IPR015947 PUA-like superfamily HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 Gene3D G3DSA:1.10.490.70 2 150 4.8E-47 T 12-10-2018 IPR038284 Histidine kinase, N-terminal domain superfamily HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 SMART SM00387 264 373 1.2E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 Gene3D G3DSA:1.10.287.130 151 220 3.0E-12 T 12-10-2018 HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 323 333 3.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 352 3.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 319 3.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 370 3.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 Gene3D G3DSA:3.30.565.10 222 374 1.8E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 266 370 1.1E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 SUPERFAMILY SSF47384 154 219 2.16E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 Pfam PF00512 His Kinase A (phospho-acceptor) domain 160 219 2.4E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 SMART SM00388 159 221 5.6E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 SUPERFAMILY SSF55874 212 372 1.31E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_14780 11b8e345acb88bf7372c1cdde449d1e3 382 Pfam PF09385 Histidine kinase N terminal 7 136 2.5E-42 T 12-10-2018 IPR018984 Histidine kinase, N-terminal HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SUPERFAMILY SSF48452 186 409 4.03E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 Pfam PF13432 Tetratricopeptide repeat 278 323 0.0095 T 12-10-2018 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 Gene3D G3DSA:1.25.40.10 331 417 5.4E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SUPERFAMILY SSF48452 33 198 1.99E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 Pfam PF13176 Tetratricopeptide repeat 139 166 0.005 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 Gene3D G3DSA:1.25.40.10 2 201 2.6E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 Pfam PF14559 Tetratricopeptide repeat 353 416 1.6E-6 T 12-10-2018 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 Pfam PF14559 Tetratricopeptide repeat 48 103 7.2E-8 T 12-10-2018 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 Gene3D G3DSA:1.25.40.10 202 330 2.1E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SMART SM00028 170 203 150.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SMART SM00028 339 372 0.89 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SMART SM00028 373 406 85.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SMART SM00028 237 270 13.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SMART SM00028 66 99 78.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SMART SM00028 134 167 2.6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SMART SM00028 271 304 23.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SMART SM00028 32 65 260.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_03305 54c118b3b38495c4a01903417421dbeb 421 SMART SM00028 100 133 150.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_02370 ec34fba5cb02106c4025078bd45ff151 264 SMART SM00382 31 233 2.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_02370 ec34fba5cb02106c4025078bd45ff151 264 Gene3D G3DSA:3.40.50.300 1 261 5.7E-58 T 12-10-2018 HW35_02370 ec34fba5cb02106c4025078bd45ff151 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_02370 ec34fba5cb02106c4025078bd45ff151 264 SUPERFAMILY SSF52540 2 235 3.63E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02370 ec34fba5cb02106c4025078bd45ff151 264 Pfam PF00005 ABC transporter 22 177 1.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_14830 40b157a6f492a87fcb47929afb5b3945 454 SUPERFAMILY SSF56059 211 428 1.44E-13 T 12-10-2018 HW35_14830 40b157a6f492a87fcb47929afb5b3945 454 Pfam PF14398 YheC/D like ATP-grasp 187 441 5.0E-81 T 12-10-2018 IPR026838 Endospore coat-associated protein YheC/D HW35_14830 40b157a6f492a87fcb47929afb5b3945 454 Gene3D G3DSA:3.30.470.20 311 433 1.7E-5 T 12-10-2018 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 SUPERFAMILY SSF47384 218 300 1.18E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 6.7E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 435 6.7E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 6.7E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 6.7E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 Gene3D G3DSA:3.30.565.10 304 456 2.3E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_11165 eec803eab744987e85da3bcea0af0c47 456 SUPERFAMILY SSF55874 290 454 2.88E-47 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_11165 eec803eab744987e85da3bcea0af0c47 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 455 5.9E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_11165 eec803eab744987e85da3bcea0af0c47 456 Gene3D G3DSA:1.20.1480.50 144 239 2.5E-18 T 12-10-2018 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 SMART SM00388 234 300 1.1E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 SMART SM00304 181 233 7.0E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 SMART SM00387 345 456 1.2E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_11165 eec803eab744987e85da3bcea0af0c47 456 Pfam PF00672 HAMP domain 181 229 1.9E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 Gene3D G3DSA:1.10.287.130 240 301 7.8E-17 T 12-10-2018 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 SUPERFAMILY SSF158472 181 230 9.42E-10 T 12-10-2018 HW35_11165 eec803eab744987e85da3bcea0af0c47 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 299 5.5E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_06200 a143cf17c69865e54cea2722bad88494 509 Pfam PF13192 Thioredoxin domain 124 193 7.5E-9 T 12-10-2018 IPR012336 Thioredoxin-like fold HW35_06200 a143cf17c69865e54cea2722bad88494 509 PIRSF PIRSF000238 2 509 7.5E-261 T 12-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 HW35_06200 a143cf17c69865e54cea2722bad88494 509 Gene3D G3DSA:3.40.30.80 2 199 1.8E-62 T 12-10-2018 HW35_06200 a143cf17c69865e54cea2722bad88494 509 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 488 1.3E-45 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 SUPERFAMILY SSF52833 2 100 4.92E-29 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_06200 a143cf17c69865e54cea2722bad88494 509 SUPERFAMILY SSF52833 103 196 4.23E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 3.4E-39 T 12-10-2018 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 3.4E-39 T 12-10-2018 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 3.4E-39 T 12-10-2018 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 3.4E-39 T 12-10-2018 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 481 3.4E-39 T 12-10-2018 HW35_06200 a143cf17c69865e54cea2722bad88494 509 Gene3D G3DSA:3.50.50.60 319 441 2.9E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_06200 a143cf17c69865e54cea2722bad88494 509 Gene3D G3DSA:3.50.50.60 209 499 2.9E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 2.9E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 2.9E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 2.9E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 2.9E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 2.9E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 2.9E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 2.9E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 2.9E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 469 487 2.9E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_06200 a143cf17c69865e54cea2722bad88494 509 SUPERFAMILY SSF51905 200 505 7.66E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_06200 a143cf17c69865e54cea2722bad88494 509 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 509 5.8E-246 T 12-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 HW35_01685 eccf481c1352dd85f781e3b8947ad9e1 186 SMART SM00471 19 148 1.0E-6 T 12-10-2018 IPR003607 HD/PDEase domain HW35_01685 eccf481c1352dd85f781e3b8947ad9e1 186 Gene3D G3DSA:1.10.3210.10 4 173 1.0E-16 T 12-10-2018 HW35_01685 eccf481c1352dd85f781e3b8947ad9e1 186 Pfam PF01966 HD domain 26 137 4.1E-15 T 12-10-2018 IPR006674 HD domain HW35_01685 eccf481c1352dd85f781e3b8947ad9e1 186 TIGRFAM TIGR00277 HDIG: HDIG domain 23 92 1.3E-9 T 12-10-2018 IPR006675 HDIG domain HW35_01685 eccf481c1352dd85f781e3b8947ad9e1 186 SUPERFAMILY SSF109604 18 167 3.14E-21 T 12-10-2018 HW35_15010 a3641dea0404f4fe933eb8d6b80e24ba 258 Gene3D G3DSA:3.90.226.10 2 198 2.5E-70 T 12-10-2018 HW35_15010 a3641dea0404f4fe933eb8d6b80e24ba 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 257 6.7E-64 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 HW35_15010 a3641dea0404f4fe933eb8d6b80e24ba 258 SUPERFAMILY SSF52096 1 257 2.05E-85 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_15010 a3641dea0404f4fe933eb8d6b80e24ba 258 Gene3D G3DSA:1.10.12.10 199 258 5.6E-24 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal HW35_15010 a3641dea0404f4fe933eb8d6b80e24ba 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 HW35_02165 05856dff46595d4f6f22aa4e48be971d 294 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 24 226 7.9E-69 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT HW35_02165 05856dff46595d4f6f22aa4e48be971d 294 Gene3D G3DSA:3.30.70.120 202 278 2.9E-24 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HW35_02165 05856dff46595d4f6f22aa4e48be971d 294 PIRSF PIRSF006483 3 293 1.8E-99 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT HW35_02165 05856dff46595d4f6f22aa4e48be971d 294 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 2.1E-21 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 HW35_03490 cea0424efc9a4fa689eeca3f806a7ce6 86 PIRSF PIRSF010606 1 86 5.3E-39 T 12-10-2018 IPR016571 Spore coat assembly protein CotJB HW35_03490 cea0424efc9a4fa689eeca3f806a7ce6 86 Pfam PF12652 CotJB protein 10 85 5.6E-29 T 12-10-2018 IPR024207 Spore coat assembly protein CotJB, domain HW35_07835 35341545b6aad05c79f7ae558a072ec6 228 SMART SM00382 27 223 5.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_07835 35341545b6aad05c79f7ae558a072ec6 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 4.4E-89 T 12-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 HW35_07835 35341545b6aad05c79f7ae558a072ec6 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_07835 35341545b6aad05c79f7ae558a072ec6 228 SUPERFAMILY SSF52540 1 223 5.99E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07835 35341545b6aad05c79f7ae558a072ec6 228 Pfam PF00005 ABC transporter 19 165 1.0E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_07835 35341545b6aad05c79f7ae558a072ec6 228 Gene3D G3DSA:3.40.50.300 1 227 6.3E-66 T 12-10-2018 HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 SUPERFAMILY SSF52467 182 380 1.56E-39 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 Gene3D G3DSA:3.40.50.1220 212 396 3.2E-38 T 12-10-2018 HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 Gene3D G3DSA:3.40.50.970 409 607 5.8E-45 T 12-10-2018 HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 SUPERFAMILY SSF52518 2 209 7.36E-33 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 471 490 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 5 637 2.6E-292 T 12-10-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 Gene3D G3DSA:3.40.50.970 2 204 7.6E-32 T 12-10-2018 HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 435 594 4.5E-40 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 196 8.4E-35 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 Hamap MF_01669 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase [iolD]. 1 639 57.692 T 12-10-2018 IPR023757 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, Firmicutes GO:0000287|GO:0016787|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 219 350 7.8E-33 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 HW35_12550 a6bfd4c32a1fee681d6033b037e0ce2b 639 SUPERFAMILY SSF52518 412 627 3.5E-54 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_08925 bf24ba3ecbc63e2d5e8a7d750a2078d9 245 Pfam PF00005 ABC transporter 22 170 5.5E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_08925 bf24ba3ecbc63e2d5e8a7d750a2078d9 245 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_08925 bf24ba3ecbc63e2d5e8a7d750a2078d9 245 SUPERFAMILY SSF52540 6 240 4.71E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_08925 bf24ba3ecbc63e2d5e8a7d750a2078d9 245 Gene3D G3DSA:3.40.50.300 6 245 3.1E-79 T 12-10-2018 HW35_08925 bf24ba3ecbc63e2d5e8a7d750a2078d9 245 SMART SM00382 31 218 3.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_08925 bf24ba3ecbc63e2d5e8a7d750a2078d9 245 PIRSF PIRSF039085 3 245 6.1E-117 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 139 160 3.9E-30 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 3.9E-30 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 192 202 3.9E-30 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 3.9E-30 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 SUPERFAMILY SSF52374 2 324 1.08E-99 T 12-10-2018 HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 Gene3D G3DSA:3.40.50.620 4 323 2.0E-140 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 Pfam PF00579 tRNA synthetases class I (W and Y) 3 281 5.8E-84 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 325 42.813 T 12-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 324 9.5E-122 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HW35_15295 8356bb630925eabfbb5df802f47a7ce3 329 Gene3D G3DSA:1.10.240.10 183 293 2.0E-140 T 12-10-2018 HW35_00705 4d3f82451bf09f8f0f237066f871970f 332 Gene3D G3DSA:3.40.190.10 40 313 1.3E-101 T 12-10-2018 HW35_00705 4d3f82451bf09f8f0f237066f871970f 332 Gene3D G3DSA:3.40.190.10 119 221 1.3E-101 T 12-10-2018 HW35_00705 4d3f82451bf09f8f0f237066f871970f 332 Pfam PF09084 NMT1/THI5 like 47 261 1.3E-77 T 12-10-2018 IPR015168 SsuA/THI5-like HW35_00705 4d3f82451bf09f8f0f237066f871970f 332 SUPERFAMILY SSF53850 39 324 2.73E-43 T 12-10-2018 HW35_04390 5c730e578a5e78d82e761f9b0b74e467 313 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 32.296 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 HW35_04390 5c730e578a5e78d82e761f9b0b74e467 313 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 286 9.7E-92 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 HW35_04390 5c730e578a5e78d82e761f9b0b74e467 313 Gene3D G3DSA:3.40.1010.20 7 284 4.0E-94 T 12-10-2018 HW35_04390 5c730e578a5e78d82e761f9b0b74e467 313 Gene3D G3DSA:3.40.50.11270 12 103 4.0E-94 T 12-10-2018 HW35_04390 5c730e578a5e78d82e761f9b0b74e467 313 Gene3D G3DSA:3.40.1010.20 104 197 4.0E-94 T 12-10-2018 HW35_04390 5c730e578a5e78d82e761f9b0b74e467 313 Pfam PF02401 LytB protein 4 284 1.6E-80 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 HW35_03565 dbb967dd2852226a18212e6cf4044b64 395 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 50 393 1.7E-77 T 12-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 HW35_03565 dbb967dd2852226a18212e6cf4044b64 395 Pfam PF01578 Cytochrome C assembly protein 74 182 6.9E-8 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 HW35_03565 dbb967dd2852226a18212e6cf4044b64 395 Pfam PF01578 Cytochrome C assembly protein 263 390 5.1E-26 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 HW35_00020 0899cfc1e27b824c33d1196f8bf0196f 318 SUPERFAMILY SSF143865 20 252 8.76E-54 T 12-10-2018 HW35_00020 0899cfc1e27b824c33d1196f8bf0196f 318 Gene3D G3DSA:1.20.58.340 128 240 2.3E-25 T 12-10-2018 HW35_00020 0899cfc1e27b824c33d1196f8bf0196f 318 SUPERFAMILY SSF144083 253 316 3.14E-23 T 12-10-2018 HW35_00020 0899cfc1e27b824c33d1196f8bf0196f 318 Pfam PF01544 CorA-like Mg2+ transporter protein 28 314 4.7E-74 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 HW35_00020 0899cfc1e27b824c33d1196f8bf0196f 318 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 8 318 4.1E-88 T 12-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 HW35_00020 0899cfc1e27b824c33d1196f8bf0196f 318 Gene3D G3DSA:1.20.58.340 242 318 5.0E-33 T 12-10-2018 HW35_00020 0899cfc1e27b824c33d1196f8bf0196f 318 Gene3D G3DSA:3.30.460.20 6 127 1.2E-25 T 12-10-2018 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 Gene3D G3DSA:3.40.50.720 1 194 4.5E-74 T 12-10-2018 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 SUPERFAMILY SSF48179 196 292 1.26E-32 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 SUPERFAMILY SSF51735 2 186 6.93E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 311 412 3.5E-25 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 Gene3D G3DSA:1.20.5.100 195 226 2.8E-18 T 12-10-2018 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 SMART SM00984 311 413 3.6E-37 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 181 1.5E-63 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 SUPERFAMILY SSF52413 299 423 4.58E-30 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 PIRSF PIRSF000124 1 428 4.1E-135 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 PIRSF PIRSF500134 1 431 5.0E-171 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 Gene3D G3DSA:3.40.50.720 227 436 1.2E-64 T 12-10-2018 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 196 288 4.2E-37 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08780 9ea9c9be88f7e12e3769e65e8b3a8916 439 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 409 5.4E-135 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 2.2E-160 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 Gene3D G3DSA:1.10.150.300 113 200 7.0E-159 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.4E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.4E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.4E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.4E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 Gene3D G3DSA:3.40.50.300 4 281 7.0E-159 T 12-10-2018 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 Pfam PF01926 50S ribosome-binding GTPase 5 123 1.1E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 SUPERFAMILY SSF52540 3 304 2.17E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 SUPERFAMILY SSF81271 282 363 2.62E-36 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 2.6E-40 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 PIRSF PIRSF006641 1 366 6.8E-168 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 46.537 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 HW35_09890 c3d851eb20b15e2bf937d4bba1484751 366 Gene3D G3DSA:3.10.20.30 48 364 7.0E-159 T 12-10-2018 IPR012675 Beta-grasp domain superfamily HW35_09140 1b58615190837c9c9509978125f6fcb7 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 1.1E-92 T 12-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 HW35_09140 1b58615190837c9c9509978125f6fcb7 209 SUPERFAMILY SSF53271 4 207 2.49E-74 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_09140 1b58615190837c9c9509978125f6fcb7 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 3.3E-75 T 12-10-2018 HW35_09140 1b58615190837c9c9509978125f6fcb7 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 48.174 T 12-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 HW35_09140 1b58615190837c9c9509978125f6fcb7 209 Gene3D G3DSA:3.40.50.2020 1 209 2.1E-83 T 12-10-2018 HW35_14085 787c8288d0f0d6aead0f887f5664b0ed 254 Pfam PF13411 MerR HTH family regulatory protein 3 70 4.0E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_14085 787c8288d0f0d6aead0f887f5664b0ed 254 Gene3D G3DSA:1.10.490.50 163 253 3.8E-25 T 12-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain HW35_14085 787c8288d0f0d6aead0f887f5664b0ed 254 SUPERFAMILY SSF89082 163 251 8.63E-30 T 12-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain HW35_14085 787c8288d0f0d6aead0f887f5664b0ed 254 Gene3D G3DSA:1.10.1660.10 1 144 1.3E-42 T 12-10-2018 HW35_14085 787c8288d0f0d6aead0f887f5664b0ed 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 4.3E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_14085 787c8288d0f0d6aead0f887f5664b0ed 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 4.3E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_14085 787c8288d0f0d6aead0f887f5664b0ed 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 4.3E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_14085 787c8288d0f0d6aead0f887f5664b0ed 254 Pfam PF07739 TipAS antibiotic-recognition domain 135 249 6.6E-37 T 12-10-2018 IPR012925 TipAS antibiotic-recognition domain HW35_14085 787c8288d0f0d6aead0f887f5664b0ed 254 SUPERFAMILY SSF46955 3 112 5.86E-28 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily HW35_14085 787c8288d0f0d6aead0f887f5664b0ed 254 SMART SM00422 3 72 1.2E-22 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_04150 a66ebe7d79c2c313d7ff7037d1af8c22 448 PIRSF PIRSF006815 3 447 2.9E-191 T 12-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 HW35_04150 a66ebe7d79c2c313d7ff7037d1af8c22 448 Pfam PF02347 Glycine cleavage system P-protein 3 442 1.3E-161 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 HW35_04150 a66ebe7d79c2c313d7ff7037d1af8c22 448 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 50.559 T 12-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 HW35_04150 a66ebe7d79c2c313d7ff7037d1af8c22 448 Gene3D G3DSA:3.90.1150.10 73 443 8.0E-167 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_04150 a66ebe7d79c2c313d7ff7037d1af8c22 448 SUPERFAMILY SSF53383 3 443 1.3E-123 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_04150 a66ebe7d79c2c313d7ff7037d1af8c22 448 Gene3D G3DSA:3.40.640.10 84 349 8.0E-167 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 Gene3D G3DSA:3.40.50.1980 197 311 1.1E-35 T 12-10-2018 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 PRINTS PR00690 Adhesin family signature 32 50 3.5E-9 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 PRINTS PR00690 Adhesin family signature 194 215 3.5E-9 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 PRINTS PR00690 Adhesin family signature 63 76 3.5E-9 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 PRINTS PR00690 Adhesin family signature 76 93 3.5E-9 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 Gene3D G3DSA:3.40.50.1980 21 196 2.1E-55 T 12-10-2018 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 SUPERFAMILY SSF53807 14 309 3.14E-81 T 12-10-2018 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 PRINTS PR00691 Adhesin B signature 57 75 2.1E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 PRINTS PR00691 Adhesin B signature 194 211 2.1E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 PRINTS PR00691 Adhesin B signature 287 305 2.1E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 PRINTS PR00691 Adhesin B signature 76 95 2.1E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 HW35_06365 a97bb15c6aa16bcd969e4e58a0f2a11f 311 Pfam PF01297 Zinc-uptake complex component A periplasmic 35 307 4.3E-69 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 HW35_02535 efb16f2b559f8258980e771b3cf55eee 43 SUPERFAMILY SSF100985 2 40 2.22E-6 T 12-10-2018 IPR036916 Sporulation inhibitor A superfamily HW35_02535 efb16f2b559f8258980e771b3cf55eee 43 Pfam PF08970 Sporulation inhibitor A 4 40 1.6E-8 T 12-10-2018 IPR015064 Sporulation inhibitor A HW35_16425 15a78b9839fc9e1190567488a34f8d53 257 Gene3D G3DSA:3.10.290.10 182 256 3.1E-7 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HW35_16425 15a78b9839fc9e1190567488a34f8d53 257 SMART SM00363 181 238 5.1E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_16425 15a78b9839fc9e1190567488a34f8d53 257 Gene3D G3DSA:3.30.70.330 80 166 2.1E-29 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily HW35_16425 15a78b9839fc9e1190567488a34f8d53 257 Gene3D G3DSA:3.30.1370.160 2 79 2.1E-30 T 12-10-2018 HW35_16425 15a78b9839fc9e1190567488a34f8d53 257 Pfam PF01479 S4 domain 182 227 2.2E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_16425 15a78b9839fc9e1190567488a34f8d53 257 SUPERFAMILY SSF55174 35 251 2.0E-38 T 12-10-2018 HW35_04225 17b70dbb40c16fe35c457bf47e4f4527 211 Pfam PF00753 Metallo-beta-lactamase superfamily 10 192 3.0E-34 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_04225 17b70dbb40c16fe35c457bf47e4f4527 211 SUPERFAMILY SSF56281 1 209 1.28E-55 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_04225 17b70dbb40c16fe35c457bf47e4f4527 211 SMART SM00849 12 192 1.6E-47 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_04225 17b70dbb40c16fe35c457bf47e4f4527 211 Gene3D G3DSA:3.60.15.10 1 211 2.0E-67 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_01010 1ff01b740be181d4f1057ad1c9218b0d 261 Pfam PF02517 CAAX protease self-immunity 158 247 5.0E-10 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 HW35_05970 7bd87ac598f0d70623fc3d320f3a9f4e 357 PIRSF PIRSF001123 2 356 8.5E-148 T 12-10-2018 IPR008007 Peptidase M42 HW35_05970 7bd87ac598f0d70623fc3d320f3a9f4e 357 SUPERFAMILY SSF101821 71 180 1.53E-30 T 12-10-2018 HW35_05970 7bd87ac598f0d70623fc3d320f3a9f4e 357 SUPERFAMILY SSF53187 5 352 4.84E-71 T 12-10-2018 HW35_05970 7bd87ac598f0d70623fc3d320f3a9f4e 357 Pfam PF05343 M42 glutamyl aminopeptidase 46 337 5.4E-110 T 12-10-2018 IPR008007 Peptidase M42 HW35_05970 7bd87ac598f0d70623fc3d320f3a9f4e 357 Gene3D G3DSA:3.40.630.10 11 340 2.7E-116 T 12-10-2018 HW35_05970 7bd87ac598f0d70623fc3d320f3a9f4e 357 Gene3D G3DSA:2.40.30.40 75 162 2.7E-116 T 12-10-2018 IPR023367 Peptidase M42, domain 2 HW35_03065 5433ba827e2f68ab78d291d0a9799754 99 SUPERFAMILY SSF117916 2 98 2.03E-32 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily HW35_03065 5433ba827e2f68ab78d291d0a9799754 99 Gene3D G3DSA:3.30.300.130 2 99 3.2E-38 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily HW35_03065 5433ba827e2f68ab78d291d0a9799754 99 Pfam PF01883 Iron-sulfur cluster assembly protein 4 77 2.0E-21 T 12-10-2018 IPR002744 MIP18 family-like HW35_04605 bdac6acee7bc6daf6bfbab47a1176bea 153 PIRSF PIRSF006019 1 149 1.3E-62 T 12-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 HW35_04605 bdac6acee7bc6daf6bfbab47a1176bea 153 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HW35_04605 bdac6acee7bc6daf6bfbab47a1176bea 153 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 149 5.0E-88 T 12-10-2018 IPR013404 Competence operon E, ComEB HW35_04605 bdac6acee7bc6daf6bfbab47a1176bea 153 SUPERFAMILY SSF53927 7 139 2.48E-42 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 HW35_04605 bdac6acee7bc6daf6bfbab47a1176bea 153 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 1.6E-29 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain HW35_04605 bdac6acee7bc6daf6bfbab47a1176bea 153 Gene3D G3DSA:3.40.140.10 2 147 3.1E-49 T 12-10-2018 HW35_08650 1e521ee2fea0f5d06f883b53ffee6fc4 80 Gene3D G3DSA:3.40.30.10 2 80 1.4E-16 T 12-10-2018 HW35_08650 1e521ee2fea0f5d06f883b53ffee6fc4 80 Pfam PF00462 Glutaredoxin 4 52 1.5E-11 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 HW35_08650 1e521ee2fea0f5d06f883b53ffee6fc4 80 SUPERFAMILY SSF52833 2 67 1.99E-14 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_15260 f4148021965e1311dcf4afb90baa1626 257 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 65 256 1.6E-53 T 12-10-2018 IPR018728 Domain of unknown function DUF2268 HW35_12925 0b6da0aaeda368ed756ad1f6692b5c9b 205 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 3 58 1.8E-25 T 12-10-2018 HW35_12925 0b6da0aaeda368ed756ad1f6692b5c9b 205 Gene3D G3DSA:3.90.79.10 42 205 3.3E-42 T 12-10-2018 HW35_12925 0b6da0aaeda368ed756ad1f6692b5c9b 205 Pfam PF00293 NUDIX domain 71 177 6.2E-11 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HW35_12925 0b6da0aaeda368ed756ad1f6692b5c9b 205 SUPERFAMILY SSF55811 49 195 1.33E-28 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 HW35_07065 1ff2ebcf8f76c157b970e7f67bf32da7 409 SUPERFAMILY SSF53383 2 401 1.32E-134 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_07065 1ff2ebcf8f76c157b970e7f67bf32da7 409 Pfam PF00266 Aminotransferase class-V 23 394 1.2E-163 T 12-10-2018 IPR000192 Aminotransferase class V domain HW35_07065 1ff2ebcf8f76c157b970e7f67bf32da7 409 Gene3D G3DSA:3.40.640.10 34 294 8.2E-185 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_07065 1ff2ebcf8f76c157b970e7f67bf32da7 409 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 406 6.1E-194 T 12-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 HW35_07065 1ff2ebcf8f76c157b970e7f67bf32da7 409 PIRSF PIRSF005572 20 408 3.9E-58 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 HW35_07065 1ff2ebcf8f76c157b970e7f67bf32da7 409 Gene3D G3DSA:3.90.1150.10 6 398 8.2E-185 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_07065 1ff2ebcf8f76c157b970e7f67bf32da7 409 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site HW35_02110 fb81a651fc151650f9abab758e2d0a7e 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 100 112 6.4E-26 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_02110 fb81a651fc151650f9abab758e2d0a7e 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 6.4E-26 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_02110 fb81a651fc151650f9abab758e2d0a7e 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 6.4E-26 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_02110 fb81a651fc151650f9abab758e2d0a7e 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 6.4E-26 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_02110 fb81a651fc151650f9abab758e2d0a7e 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 113 128 6.4E-26 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_02110 fb81a651fc151650f9abab758e2d0a7e 146 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 10 138 4.4E-42 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 HW35_02110 fb81a651fc151650f9abab758e2d0a7e 146 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 12-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 HW35_02110 fb81a651fc151650f9abab758e2d0a7e 146 Gene3D G3DSA:2.40.100.10 1 146 1.1E-61 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily HW35_02110 fb81a651fc151650f9abab758e2d0a7e 146 PIRSF PIRSF001467 4 146 3.8E-42 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 HW35_02110 fb81a651fc151650f9abab758e2d0a7e 146 SUPERFAMILY SSF50891 14 138 2.48E-48 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily HW35_09630 e55e9d4fc63108e87bb6439ee9b80a9d 243 Gene3D G3DSA:1.10.10.10 16 81 1.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_09630 e55e9d4fc63108e87bb6439ee9b80a9d 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 8.8E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_09630 e55e9d4fc63108e87bb6439ee9b80a9d 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 8.8E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_09630 e55e9d4fc63108e87bb6439ee9b80a9d 243 SUPERFAMILY SSF46785 13 84 2.14E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_09630 e55e9d4fc63108e87bb6439ee9b80a9d 243 SMART SM00345 23 81 1.0E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_09630 e55e9d4fc63108e87bb6439ee9b80a9d 243 Gene3D G3DSA:1.20.120.530 84 224 2.8E-15 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal HW35_09630 e55e9d4fc63108e87bb6439ee9b80a9d 243 Pfam PF07729 FCD domain 90 208 4.7E-14 T 12-10-2018 IPR011711 GntR, C-terminal HW35_09630 e55e9d4fc63108e87bb6439ee9b80a9d 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 2.1E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_09630 e55e9d4fc63108e87bb6439ee9b80a9d 243 SUPERFAMILY SSF48008 86 226 8.11E-18 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal HW35_09630 e55e9d4fc63108e87bb6439ee9b80a9d 243 SMART SM00895 90 219 5.7E-6 T 12-10-2018 IPR011711 GntR, C-terminal HW35_02230 9924b416e06bebef798984ab1241a480 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 205 217 1.9E-12 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_02230 9924b416e06bebef798984ab1241a480 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 378 394 1.9E-12 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_02230 9924b416e06bebef798984ab1241a480 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 418 432 1.9E-12 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_02230 9924b416e06bebef798984ab1241a480 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 221 234 1.9E-12 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_02230 9924b416e06bebef798984ab1241a480 463 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 463 1.0E-187 T 12-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 HW35_02230 9924b416e06bebef798984ab1241a480 463 Pfam PF01336 OB-fold nucleic acid binding domain 21 97 2.8E-8 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HW35_02230 9924b416e06bebef798984ab1241a480 463 SUPERFAMILY SSF55681 105 461 1.62E-99 T 12-10-2018 HW35_02230 9924b416e06bebef798984ab1241a480 463 Gene3D G3DSA:2.40.50.140 2 105 1.0E-18 T 12-10-2018 HW35_02230 9924b416e06bebef798984ab1241a480 463 SUPERFAMILY SSF50249 12 102 4.09E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_02230 9924b416e06bebef798984ab1241a480 463 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 457 3.4E-90 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_02230 9924b416e06bebef798984ab1241a480 463 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 463 46.249 T 12-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 HW35_02230 9924b416e06bebef798984ab1241a480 463 Gene3D G3DSA:3.30.930.10 106 462 1.9E-116 T 12-10-2018 HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 Gene3D G3DSA:2.40.30.10 192 360 1.7E-125 T 12-10-2018 HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 Gene3D G3DSA:3.50.50.60 6 409 1.7E-125 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 Pfam PF03486 HI0933-like protein 3 413 1.3E-154 T 12-10-2018 HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 412 3.3E-148 T 12-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-6 T 12-10-2018 HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.1E-6 T 12-10-2018 HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 SUPERFAMILY SSF51905 1 416 5.67E-63 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 Gene3D G3DSA:1.10.8.260 279 343 1.7E-125 T 12-10-2018 IPR023166 HI0933-like insert domain superfamily HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 SUPERFAMILY SSF160996 193 361 1.96E-48 T 12-10-2018 HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 4.5E-9 T 12-10-2018 HW35_06100 35f11f287b6f7cc9505f2e86231a9a9d 424 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 4.5E-9 T 12-10-2018 HW35_15940 66bc8a9cfa1d4783842e3551b0f7a8ee 435 SUPERFAMILY SSF47005 122 168 2.88E-13 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 HW35_15940 66bc8a9cfa1d4783842e3551b0f7a8ee 435 Pfam PF02817 e3 binding domain 128 162 9.1E-15 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 HW35_15940 66bc8a9cfa1d4783842e3551b0f7a8ee 435 Pfam PF00364 Biotin-requiring enzyme 4 75 3.4E-25 T 12-10-2018 IPR000089 Biotin/lipoyl attachment HW35_15940 66bc8a9cfa1d4783842e3551b0f7a8ee 435 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 HW35_15940 66bc8a9cfa1d4783842e3551b0f7a8ee 435 Gene3D G3DSA:3.30.559.10 187 431 2.5E-91 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 HW35_15940 66bc8a9cfa1d4783842e3551b0f7a8ee 435 SUPERFAMILY SSF52777 195 433 4.45E-89 T 12-10-2018 HW35_15940 66bc8a9cfa1d4783842e3551b0f7a8ee 435 SUPERFAMILY SSF51230 3 89 3.4E-28 T 12-10-2018 IPR011053 Single hybrid motif HW35_15940 66bc8a9cfa1d4783842e3551b0f7a8ee 435 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 205 433 5.6E-90 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 HW35_15940 66bc8a9cfa1d4783842e3551b0f7a8ee 435 Gene3D G3DSA:4.10.320.10 117 170 1.5E-21 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 HW35_15940 66bc8a9cfa1d4783842e3551b0f7a8ee 435 Gene3D G3DSA:2.40.50.100 2 81 4.2E-29 T 12-10-2018 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 Gene3D G3DSA:3.40.50.2300 64 311 2.7E-88 T 12-10-2018 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 Pfam PF13377 Periplasmic binding protein-like domain 170 332 4.6E-30 T 12-10-2018 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 Gene3D G3DSA:1.10.260.40 3 61 5.7E-28 T 12-10-2018 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 4.4E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 4.4E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 SUPERFAMILY SSF53822 63 333 7.46E-85 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 4.7E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 TIGRFAM TIGR01481 ccpA: catabolite control protein A 3 333 2.7E-161 T 12-10-2018 IPR006377 Catabolite control protein A GO:0006355 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 12-10-2018 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 Gene3D G3DSA:3.40.50.2300 162 292 2.7E-88 T 12-10-2018 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 SUPERFAMILY SSF47413 3 61 2.38E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_05920 22aec08ab8ae90078917cf185d0d0b5a 334 SMART SM00354 3 73 1.5E-38 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_09375 675aeb97d2378c000e5c63489e230ee9 135 SUPERFAMILY SSF53098 40 93 6.91E-6 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_09375 675aeb97d2378c000e5c63489e230ee9 135 Gene3D G3DSA:3.30.420.10 40 130 2.3E-7 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_17395 47f836fa47fa097d58afdba102a83f4b 364 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 3 354 3.0E-51 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HW35_17395 47f836fa47fa097d58afdba102a83f4b 364 Pfam PF03845 Spore germination protein 4 319 5.3E-40 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HW35_00670 2dc5c40fde47d98df513071e65ab8901 270 Gene3D G3DSA:3.40.1190.20 1 268 4.0E-106 T 12-10-2018 IPR029056 Ribokinase-like HW35_00670 2dc5c40fde47d98df513071e65ab8901 270 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 258 1.8E-110 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00670 2dc5c40fde47d98df513071e65ab8901 270 Pfam PF08543 Phosphomethylpyrimidine kinase 11 256 1.3E-100 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 HW35_00670 2dc5c40fde47d98df513071e65ab8901 270 SUPERFAMILY SSF53613 3 261 2.03E-85 T 12-10-2018 IPR029056 Ribokinase-like HW35_13005 860dafb4f3f16e423e79c6875263ada5 207 SMART SM00419 150 198 8.6E-5 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_13005 860dafb4f3f16e423e79c6875263ada5 207 Pfam PF13545 Crp-like helix-turn-helix domain 138 200 6.1E-11 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_13005 860dafb4f3f16e423e79c6875263ada5 207 Pfam PF00027 Cyclic nucleotide-binding domain 21 106 1.1E-17 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain HW35_13005 860dafb4f3f16e423e79c6875263ada5 207 Gene3D G3DSA:2.60.120.1460 8 207 6.9E-45 T 12-10-2018 HW35_13005 860dafb4f3f16e423e79c6875263ada5 207 SUPERFAMILY SSF46785 137 206 1.7E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13005 860dafb4f3f16e423e79c6875263ada5 207 SUPERFAMILY SSF51206 15 130 3.67E-27 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 1.2E-42 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 SUPERFAMILY SSF56059 128 399 1.59E-110 T 12-10-2018 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Gene3D G3DSA:3.30.470.20 659 929 3.4E-107 T 12-10-2018 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Gene3D G3DSA:3.30.470.20 120 401 1.2E-125 T 12-10-2018 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 2.2E-80 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 867 1.9E-36 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 SUPERFAMILY SSF52440 550 668 7.91E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HW35_16485 c3ae86b46688928106e98100a03ff470 1068 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 SUPERFAMILY SSF56059 666 927 7.25E-103 T 12-10-2018 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Gene3D G3DSA:1.10.1030.10 403 546 3.4E-46 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.0E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.0E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.0E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.0E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.0E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 2.0E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 2.0E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Gene3D G3DSA:3.40.50.20 1 116 2.4E-48 T 12-10-2018 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Pfam PF02142 MGS-like domain 950 1036 2.3E-19 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain HW35_16485 c3ae86b46688928106e98100a03ff470 1068 SUPERFAMILY SSF48108 395 546 5.89E-50 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 SUPERFAMILY SSF52440 1 127 2.73E-49 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1063 13.646 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Gene3D G3DSA:3.40.50.1380 930 1065 1.8E-35 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HW35_16485 c3ae86b46688928106e98100a03ff470 1068 SUPERFAMILY SSF52335 929 1052 5.49E-31 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.247 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 SMART SM01096 420 540 5.7E-68 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_16485 c3ae86b46688928106e98100a03ff470 1068 SMART SM00851 949 1036 7.7E-28 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain HW35_16485 c3ae86b46688928106e98100a03ff470 1068 Gene3D G3DSA:3.40.50.20 547 655 4.2E-45 T 12-10-2018 HW35_14140 144b1b2e7884e1a14dd9aaee20fccd49 399 Gene3D G3DSA:3.90.1150.10 21 385 2.3E-140 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_14140 144b1b2e7884e1a14dd9aaee20fccd49 399 Pfam PF00202 Aminotransferase class-III 18 391 8.2E-112 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_14140 144b1b2e7884e1a14dd9aaee20fccd49 399 SUPERFAMILY SSF53383 9 393 1.95E-119 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_14140 144b1b2e7884e1a14dd9aaee20fccd49 399 Gene3D G3DSA:3.40.640.10 56 301 2.3E-140 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_14140 144b1b2e7884e1a14dd9aaee20fccd49 399 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 12 395 67.723 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HW35_14140 144b1b2e7884e1a14dd9aaee20fccd49 399 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 13 392 1.8E-148 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HW35_14140 144b1b2e7884e1a14dd9aaee20fccd49 399 PIRSF PIRSF000521 4 166 3.7E-11 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_14140 144b1b2e7884e1a14dd9aaee20fccd49 399 PIRSF PIRSF000521 169 395 9.1E-33 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_14140 144b1b2e7884e1a14dd9aaee20fccd49 399 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 219 256 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_05260 f5120fa01e798bfef508638080e67ce2 555 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 97 116 5.3E-34 T 12-10-2018 HW35_05260 f5120fa01e798bfef508638080e67ce2 555 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 469 488 5.3E-34 T 12-10-2018 HW35_05260 f5120fa01e798bfef508638080e67ce2 555 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 492 510 5.3E-34 T 12-10-2018 HW35_05260 f5120fa01e798bfef508638080e67ce2 555 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 439 458 5.3E-34 T 12-10-2018 HW35_05260 f5120fa01e798bfef508638080e67ce2 555 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 368 5.3E-34 T 12-10-2018 HW35_05260 f5120fa01e798bfef508638080e67ce2 555 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 5 533 1.1E-281 T 12-10-2018 IPR014251 Sporulation protease LonB HW35_05260 f5120fa01e798bfef508638080e67ce2 555 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 345 534 1.1E-35 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 HW35_05260 f5120fa01e798bfef508638080e67ce2 555 SMART SM00382 89 267 1.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_05260 f5120fa01e798bfef508638080e67ce2 555 SUPERFAMILY SSF54211 351 533 4.17E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_05260 f5120fa01e798bfef508638080e67ce2 555 Gene3D G3DSA:3.30.230.10 345 552 1.3E-52 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_05260 f5120fa01e798bfef508638080e67ce2 555 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 442 450 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 HW35_05260 f5120fa01e798bfef508638080e67ce2 555 Gene3D G3DSA:3.40.50.300 52 124 2.3E-11 T 12-10-2018 HW35_05260 f5120fa01e798bfef508638080e67ce2 555 Gene3D G3DSA:3.40.50.300 125 263 8.9E-22 T 12-10-2018 HW35_05260 f5120fa01e798bfef508638080e67ce2 555 SUPERFAMILY SSF52540 55 328 2.16E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05260 f5120fa01e798bfef508638080e67ce2 555 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 265 3.4E-19 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_05250 01806772410fe5cf8bcee8c4502b8293 193 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 3.1E-70 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 HW35_05250 01806772410fe5cf8bcee8c4502b8293 193 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.261 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 HW35_05250 01806772410fe5cf8bcee8c4502b8293 193 SUPERFAMILY SSF52540 16 192 8.15E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05250 01806772410fe5cf8bcee8c4502b8293 193 Pfam PF01926 50S ribosome-binding GTPase 26 143 5.3E-20 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_05250 01806772410fe5cf8bcee8c4502b8293 193 Gene3D G3DSA:3.40.50.300 1 193 1.9E-54 T 12-10-2018 HW35_12705 ff9d655f125e23f565d9d5a70f35b627 817 Pfam PF02687 FtsX-like permease family 274 361 2.2E-7 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HW35_00405 53d2f8d41cb269c6496416ea8f2ad523 672 SMART SM00304 315 367 1.5E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_00405 53d2f8d41cb269c6496416ea8f2ad523 672 SMART SM00304 433 493 94.0 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_00405 53d2f8d41cb269c6496416ea8f2ad523 672 SUPERFAMILY SSF103190 101 202 1.45E-12 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily HW35_00405 53d2f8d41cb269c6496416ea8f2ad523 672 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 462 624 4.7E-36 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HW35_00405 53d2f8d41cb269c6496416ea8f2ad523 672 Gene3D G3DSA:3.30.450.20 88 192 1.4E-39 T 12-10-2018 HW35_00405 53d2f8d41cb269c6496416ea8f2ad523 672 SMART SM00283 396 671 2.0E-51 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HW35_00405 53d2f8d41cb269c6496416ea8f2ad523 672 Pfam PF02743 Cache domain 47 277 6.3E-40 T 12-10-2018 IPR033479 Double Cache domain 1 HW35_00405 53d2f8d41cb269c6496416ea8f2ad523 672 Gene3D G3DSA:1.10.287.950 351 671 3.6E-61 T 12-10-2018 HW35_00405 53d2f8d41cb269c6496416ea8f2ad523 672 SUPERFAMILY SSF58104 335 671 1.57E-65 T 12-10-2018 HW35_00405 53d2f8d41cb269c6496416ea8f2ad523 672 Gene3D G3DSA:3.30.450.20 193 284 1.4E-39 T 12-10-2018 HW35_13275 163d9ea66b1ab65ee4627bc00be10fb7 199 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 186 7.5E-82 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 HW35_13275 163d9ea66b1ab65ee4627bc00be10fb7 199 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 198 41.183 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 HW35_13275 163d9ea66b1ab65ee4627bc00be10fb7 199 Gene3D G3DSA:3.20.19.10 1 174 4.1E-73 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 HW35_13275 163d9ea66b1ab65ee4627bc00be10fb7 199 SUPERFAMILY SSF52016 1 192 8.04E-61 T 12-10-2018 HW35_13275 163d9ea66b1ab65ee4627bc00be10fb7 199 Pfam PF00694 Aconitase C-terminal domain 2 123 1.7E-36 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 HW35_11575 2754ea48ff9077e10491a0f19cbee609 240 Pfam PF02517 CAAX protease self-immunity 124 209 8.3E-18 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 HW35_10945 e2d29e5aac0095090339713b41d34c67 355 Gene3D G3DSA:3.30.300.210 213 355 1.4E-14 T 12-10-2018 IPR038501 Spore germination GerAC superfamily HW35_10945 e2d29e5aac0095090339713b41d34c67 355 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 195 352 3.5E-26 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HW35_10945 e2d29e5aac0095090339713b41d34c67 355 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 354 2.9E-75 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HW35_09360 72307b2e9c436570124b6bc4327b8892 73 Hamap MF_01863 UPF0741 protein . 1 73 30.238 T 12-10-2018 IPR020880 Protein of unknown function UPF0741 HW35_09360 72307b2e9c436570124b6bc4327b8892 73 Pfam PF07293 Protein of unknown function (DUF1450) 8 73 6.1E-8 T 12-10-2018 IPR009910 Protein of unknown function DUF1450 HW35_07090 68db7492e70737c498e1c1517dc6bf1e 341 Gene3D G3DSA:3.40.50.300 1 245 9.3E-76 T 12-10-2018 HW35_07090 68db7492e70737c498e1c1517dc6bf1e 341 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_07090 68db7492e70737c498e1c1517dc6bf1e 341 SMART SM00930 263 338 2.2E-29 T 12-10-2018 IPR018449 NIL domain HW35_07090 68db7492e70737c498e1c1517dc6bf1e 341 SUPERFAMILY SSF52540 1 240 3.22E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07090 68db7492e70737c498e1c1517dc6bf1e 341 SMART SM00382 30 226 7.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_07090 68db7492e70737c498e1c1517dc6bf1e 341 SUPERFAMILY SSF55021 249 339 6.07E-25 T 12-10-2018 HW35_07090 68db7492e70737c498e1c1517dc6bf1e 341 Pfam PF00005 ABC transporter 22 169 3.2E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_07090 68db7492e70737c498e1c1517dc6bf1e 341 Gene3D G3DSA:3.30.70.260 246 341 6.9E-32 T 12-10-2018 HW35_07090 68db7492e70737c498e1c1517dc6bf1e 341 Pfam PF09383 NIL domain 266 337 4.9E-23 T 12-10-2018 IPR018449 NIL domain HW35_06950 e730a5bf7bb305d42d9056a27f0b60fd 108 SUPERFAMILY SSF52833 2 106 4.42E-44 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_06950 e730a5bf7bb305d42d9056a27f0b60fd 108 Pfam PF07315 Protein of unknown function (DUF1462) 10 101 1.3E-40 T 12-10-2018 IPR009190 Protein of unknown function DUF1462 HW35_06950 e730a5bf7bb305d42d9056a27f0b60fd 108 Gene3D G3DSA:3.40.30.30 1 105 1.2E-40 T 12-10-2018 IPR038218 YuzD-like superfamily HW35_06950 e730a5bf7bb305d42d9056a27f0b60fd 108 PIRSF PIRSF010603 2 107 8.2E-44 T 12-10-2018 IPR009190 Protein of unknown function DUF1462 HW35_02970 abd217bca9bd2ab3a4391a3e89590050 218 Pfam PF13456 Reverse transcriptase-like 78 205 4.1E-15 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 HW35_02970 abd217bca9bd2ab3a4391a3e89590050 218 SUPERFAMILY SSF53098 73 208 2.28E-20 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_02970 abd217bca9bd2ab3a4391a3e89590050 218 Gene3D G3DSA:3.30.420.10 73 217 1.7E-28 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_13950 b9f7cf41c3aefbf075bb93a31dd48a96 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 1.1E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_13950 b9f7cf41c3aefbf075bb93a31dd48a96 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 407 1.1E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_13950 b9f7cf41c3aefbf075bb93a31dd48a96 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 427 1.1E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_13950 b9f7cf41c3aefbf075bb93a31dd48a96 436 SUPERFAMILY SSF55874 281 428 3.67E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_13950 b9f7cf41c3aefbf075bb93a31dd48a96 436 Gene3D G3DSA:3.30.565.10 281 434 4.0E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_13950 b9f7cf41c3aefbf075bb93a31dd48a96 436 SMART SM00387 318 430 4.1E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_13950 b9f7cf41c3aefbf075bb93a31dd48a96 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 429 1.4E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_01865 e43a2ad45f5c7778db4e38b481ddb0af 260 SUPERFAMILY SSF55781 65 254 5.62E-56 T 12-10-2018 HW35_01865 e43a2ad45f5c7778db4e38b481ddb0af 260 SUPERFAMILY SSF46785 7 80 8.91E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_01865 e43a2ad45f5c7778db4e38b481ddb0af 260 Pfam PF01614 Bacterial transcriptional regulator 124 248 2.1E-41 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal HW35_01865 e43a2ad45f5c7778db4e38b481ddb0af 260 Pfam PF09339 IclR helix-turn-helix domain 9 59 1.2E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 HW35_01865 e43a2ad45f5c7778db4e38b481ddb0af 260 SMART SM00346 7 97 4.0E-27 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 HW35_01865 e43a2ad45f5c7778db4e38b481ddb0af 260 Gene3D G3DSA:3.30.450.40 80 256 2.4E-67 T 12-10-2018 IPR029016 GAF-like domain superfamily HW35_01865 e43a2ad45f5c7778db4e38b481ddb0af 260 Gene3D G3DSA:1.10.10.10 5 79 1.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 321 2.8E-151 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 Gene3D G3DSA:3.20.20.70 1 323 2.8E-149 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 2.7E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 2.7E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 2.7E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 2.7E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 2.7E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 2.7E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 SUPERFAMILY SSF51569 3 324 3.37E-144 T 12-10-2018 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 PIRSF PIRSF001415 1 325 1.6E-155 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HW35_05220 94ce7e155de5e6f30c28584d9c5ebc73 326 SMART SM01004 3 322 9.7E-234 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HW35_02340 f07b7db0774b2fdf80b06c5b8e0b6a10 206 Pfam PF02080 TrkA-C domain 135 202 1.3E-16 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HW35_02340 f07b7db0774b2fdf80b06c5b8e0b6a10 206 SUPERFAMILY SSF116726 129 204 7.85E-20 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_02340 f07b7db0774b2fdf80b06c5b8e0b6a10 206 SMART SM00345 12 71 8.4E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_02340 f07b7db0774b2fdf80b06c5b8e0b6a10 206 Gene3D G3DSA:3.30.70.1450 134 206 1.6E-18 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_02340 f07b7db0774b2fdf80b06c5b8e0b6a10 206 SUPERFAMILY SSF46785 5 75 6.13E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_02340 f07b7db0774b2fdf80b06c5b8e0b6a10 206 Gene3D G3DSA:1.10.10.10 5 124 9.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_02340 f07b7db0774b2fdf80b06c5b8e0b6a10 206 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 4.1E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_13965 667c1ff2f6ed2d4f0c23fb407fbd35e9 338 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 27 333 1.4E-81 T 12-10-2018 IPR014255 Spore coat protein CotS HW35_13965 667c1ff2f6ed2d4f0c23fb407fbd35e9 338 SUPERFAMILY SSF56112 8 300 2.04E-42 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_13965 667c1ff2f6ed2d4f0c23fb407fbd35e9 338 Gene3D G3DSA:3.30.200.20 2 103 1.4E-22 T 12-10-2018 HW35_13965 667c1ff2f6ed2d4f0c23fb407fbd35e9 338 Gene3D G3DSA:3.90.1200.10 104 335 2.0E-67 T 12-10-2018 HW35_13965 667c1ff2f6ed2d4f0c23fb407fbd35e9 338 Pfam PF01636 Phosphotransferase enzyme family 27 267 2.6E-8 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase HW35_00880 a60a7e0ff0c2c0e9e1c64126b868f52e 387 Pfam PF07690 Major Facilitator Superfamily 10 321 8.5E-57 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_00880 a60a7e0ff0c2c0e9e1c64126b868f52e 387 SUPERFAMILY SSF103473 4 381 8.89E-76 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_00880 a60a7e0ff0c2c0e9e1c64126b868f52e 387 PRINTS PR01035 Tetracycline resistance protein signature 268 289 7.4E-32 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_00880 a60a7e0ff0c2c0e9e1c64126b868f52e 387 PRINTS PR01035 Tetracycline resistance protein signature 16 32 7.4E-32 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_00880 a60a7e0ff0c2c0e9e1c64126b868f52e 387 PRINTS PR01035 Tetracycline resistance protein signature 73 97 7.4E-32 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_00880 a60a7e0ff0c2c0e9e1c64126b868f52e 387 PRINTS PR01035 Tetracycline resistance protein signature 240 260 7.4E-32 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_00880 a60a7e0ff0c2c0e9e1c64126b868f52e 387 PRINTS PR01035 Tetracycline resistance protein signature 328 351 7.4E-32 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_00880 a60a7e0ff0c2c0e9e1c64126b868f52e 387 PRINTS PR01035 Tetracycline resistance protein signature 131 153 7.4E-32 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_00880 a60a7e0ff0c2c0e9e1c64126b868f52e 387 PRINTS PR01035 Tetracycline resistance protein signature 159 179 7.4E-32 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HW35_00880 a60a7e0ff0c2c0e9e1c64126b868f52e 387 Gene3D G3DSA:1.20.1250.20 2 381 8.0E-82 T 12-10-2018 HW35_14855 b621d1e7c333e95a079e4b91dcaaf752 503 SUPERFAMILY SSF102114 163 484 1.15E-69 T 12-10-2018 HW35_14855 b621d1e7c333e95a079e4b91dcaaf752 503 SMART SM00729 172 396 9.8E-47 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HW35_14855 b621d1e7c333e95a079e4b91dcaaf752 503 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 89 491 7.9E-148 T 12-10-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ HW35_14855 b621d1e7c333e95a079e4b91dcaaf752 503 Gene3D G3DSA:3.80.30.20 134 491 1.0E-66 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HW35_14855 b621d1e7c333e95a079e4b91dcaaf752 503 Pfam PF04055 Radical SAM superfamily 180 349 3.3E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_05665 1496b8a82f9e91b73918adc3db2898c2 422 SMART SM01329 20 417 3.0E-189 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HW35_05665 1496b8a82f9e91b73918adc3db2898c2 422 SUPERFAMILY SSF53659 3 421 5.95E-144 T 12-10-2018 HW35_05665 1496b8a82f9e91b73918adc3db2898c2 422 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 21 416 4.0E-125 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HW35_05665 1496b8a82f9e91b73918adc3db2898c2 422 Gene3D G3DSA:3.40.718.10 1 422 1.1E-184 T 12-10-2018 HW35_05665 1496b8a82f9e91b73918adc3db2898c2 422 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 306 325 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 HW35_05665 1496b8a82f9e91b73918adc3db2898c2 422 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 422 1.7E-224 T 12-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 Pfam PF00361 Proton-conducting membrane transporter 130 419 5.2E-89 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 353 375 8.5E-12 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 34 53 8.5E-12 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 411 433 8.5E-12 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 81 101 8.5E-12 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 117 3.2E-20 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 154 175 1.8E-59 T 12-10-2018 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 1.8E-59 T 12-10-2018 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 1.8E-59 T 12-10-2018 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 1.8E-59 T 12-10-2018 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 107 127 1.8E-59 T 12-10-2018 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 1.8E-59 T 12-10-2018 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 1.8E-59 T 12-10-2018 HW35_09035 be647c4233b8c6ea39a627d0dbecc345 622 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 612 1.9E-205 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_16450 d3a437fbc681ad23c54338ec064a4e0b 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_16450 d3a437fbc681ad23c54338ec064a4e0b 303 Pfam PF00849 RNA pseudouridylate synthase 88 241 8.2E-35 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_16450 d3a437fbc681ad23c54338ec064a4e0b 303 SUPERFAMILY SSF55120 73 298 6.48E-82 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_16450 d3a437fbc681ad23c54338ec064a4e0b 303 SUPERFAMILY SSF55174 16 101 1.51E-15 T 12-10-2018 HW35_16450 d3a437fbc681ad23c54338ec064a4e0b 303 Gene3D G3DSA:3.30.2350.10 81 303 3.6E-77 T 12-10-2018 HW35_16450 d3a437fbc681ad23c54338ec064a4e0b 303 Pfam PF01479 S4 domain 16 61 2.2E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_16450 d3a437fbc681ad23c54338ec064a4e0b 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 299 2.4E-106 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_16450 d3a437fbc681ad23c54338ec064a4e0b 303 Gene3D G3DSA:3.10.290.10 3 68 1.6E-18 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HW35_16450 d3a437fbc681ad23c54338ec064a4e0b 303 SMART SM00363 15 79 2.8E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_01405 2a46c2e820b0f48e9a99bb977816e6a3 151 Gene3D G3DSA:1.10.260.40 1 64 2.0E-24 T 12-10-2018 HW35_01405 2a46c2e820b0f48e9a99bb977816e6a3 151 SUPERFAMILY SSF47413 1 67 1.08E-20 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_01405 2a46c2e820b0f48e9a99bb977816e6a3 151 Pfam PF01381 Helix-turn-helix 7 61 5.6E-19 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_01405 2a46c2e820b0f48e9a99bb977816e6a3 151 SMART SM00530 6 61 5.6E-20 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_02405 ac9098c2ac9dccc8da0f6bddb57ce48c 420 SUPERFAMILY SSF56672 23 346 1.78E-58 T 12-10-2018 HW35_02405 ac9098c2ac9dccc8da0f6bddb57ce48c 420 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 3.1E-49 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_02405 ac9098c2ac9dccc8da0f6bddb57ce48c 420 Pfam PF08388 Group II intron, maturase-specific domain 288 359 1.5E-20 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_02405 ac9098c2ac9dccc8da0f6bddb57ce48c 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_02405 ac9098c2ac9dccc8da0f6bddb57ce48c 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_02405 ac9098c2ac9dccc8da0f6bddb57ce48c 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_02405 ac9098c2ac9dccc8da0f6bddb57ce48c 420 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 1.6E-131 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_15555 ac9098c2ac9dccc8da0f6bddb57ce48c 420 SUPERFAMILY SSF56672 23 346 1.78E-58 T 12-10-2018 HW35_15555 ac9098c2ac9dccc8da0f6bddb57ce48c 420 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 3.1E-49 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_15555 ac9098c2ac9dccc8da0f6bddb57ce48c 420 Pfam PF08388 Group II intron, maturase-specific domain 288 359 1.5E-20 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_15555 ac9098c2ac9dccc8da0f6bddb57ce48c 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_15555 ac9098c2ac9dccc8da0f6bddb57ce48c 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_15555 ac9098c2ac9dccc8da0f6bddb57ce48c 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_15555 ac9098c2ac9dccc8da0f6bddb57ce48c 420 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 1.6E-131 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_06420 0001017b3ef76141b052f04e768de462 343 SUPERFAMILY SSF53448 24 302 1.66E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_06420 0001017b3ef76141b052f04e768de462 343 Gene3D G3DSA:3.90.550.10 152 237 5.8E-7 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_06420 0001017b3ef76141b052f04e768de462 343 Gene3D G3DSA:3.90.550.10 1 151 8.4E-20 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_06420 0001017b3ef76141b052f04e768de462 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 289 323 5.5E-4 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_06420 0001017b3ef76141b052f04e768de462 343 Gene3D G3DSA:2.160.10.10 238 337 1.4E-28 T 12-10-2018 HW35_06420 0001017b3ef76141b052f04e768de462 343 Pfam PF00483 Nucleotidyl transferase 24 147 2.7E-5 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HW35_06420 0001017b3ef76141b052f04e768de462 343 SUPERFAMILY SSF51161 248 325 9.87E-16 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily HW35_16715 92ebf8c670e282c2224a0cf8d7206773 291 Pfam PF01926 50S ribosome-binding GTPase 123 209 4.9E-18 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_16715 92ebf8c670e282c2224a0cf8d7206773 291 PIRSF PIRSF006230 1 283 3.9E-107 T 12-10-2018 IPR016478 GTPase, MTG1 HW35_16715 92ebf8c670e282c2224a0cf8d7206773 291 Gene3D G3DSA:1.10.1580.10 180 272 3.3E-31 T 12-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily HW35_16715 92ebf8c670e282c2224a0cf8d7206773 291 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 123 143 1.9E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_16715 92ebf8c670e282c2224a0cf8d7206773 291 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 169 184 1.9E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_16715 92ebf8c670e282c2224a0cf8d7206773 291 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 1.3E-118 T 12-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis HW35_16715 92ebf8c670e282c2224a0cf8d7206773 291 Gene3D G3DSA:3.40.50.300 12 179 3.6E-51 T 12-10-2018 HW35_16715 92ebf8c670e282c2224a0cf8d7206773 291 SUPERFAMILY SSF52540 9 256 4.92E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 SUPERFAMILY SSF55973 5 111 1.49E-47 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 PIRSF PIRSF000497 1 398 3.8E-180 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 Gene3D G3DSA:3.30.300.10 13 284 1.1E-182 T 12-10-2018 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 8.6E-44 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 Gene3D G3DSA:3.30.300.10 104 389 1.1E-182 T 12-10-2018 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 4.0E-50 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 5.6E-189 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 386 3.5E-71 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 SUPERFAMILY SSF55973 125 246 1.3E-53 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 SUPERFAMILY SSF55973 247 398 1.02E-71 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 60.604 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HW35_06160 5bcb9c2f8da517d2709e27327c4b4d71 399 Gene3D G3DSA:3.30.300.10 7 247 1.1E-182 T 12-10-2018 HW35_14025 c6b2a73e0d39a56c4e2ea90506a631e5 96 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 95 15.938 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HW35_14025 c6b2a73e0d39a56c4e2ea90506a631e5 96 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 2 95 1.5E-20 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HW35_14025 c6b2a73e0d39a56c4e2ea90506a631e5 96 SUPERFAMILY SSF143430 2 89 8.11E-28 T 12-10-2018 HW35_14025 c6b2a73e0d39a56c4e2ea90506a631e5 96 Gene3D G3DSA:3.30.70.240 1 96 2.4E-36 T 12-10-2018 HW35_14025 c6b2a73e0d39a56c4e2ea90506a631e5 96 PIRSF PIRSF032582 1 96 4.3E-40 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HW35_14025 c6b2a73e0d39a56c4e2ea90506a631e5 96 Pfam PF09827 CRISPR associated protein Cas2 2 78 9.2E-25 T 12-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 HW35_11765 875c7f548aac8a8b5d9b57dea17b391d 755 Gene3D G3DSA:1.10.486.10 386 549 1.9E-134 T 12-10-2018 HW35_11765 875c7f548aac8a8b5d9b57dea17b391d 755 Pfam PF13361 UvrD-like helicase C-terminal domain 280 618 1.0E-76 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HW35_11765 875c7f548aac8a8b5d9b57dea17b391d 755 SUPERFAMILY SSF52540 3 645 1.2E-194 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_11765 875c7f548aac8a8b5d9b57dea17b391d 755 Gene3D G3DSA:3.40.50.300 283 636 1.9E-134 T 12-10-2018 HW35_11765 875c7f548aac8a8b5d9b57dea17b391d 755 Gene3D G3DSA:3.40.50.300 12 277 8.8E-114 T 12-10-2018 HW35_11765 875c7f548aac8a8b5d9b57dea17b391d 755 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 8 753 0.0 T 12-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 HW35_11765 875c7f548aac8a8b5d9b57dea17b391d 755 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 275 6.0E-89 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 HW35_11765 875c7f548aac8a8b5d9b57dea17b391d 755 Gene3D G3DSA:1.10.10.160 116 190 8.8E-114 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily HW35_10160 5b5e3abee0bb8c60676ba4fa72fc4c7d 338 Gene3D G3DSA:3.40.50.300 11 174 5.7E-53 T 12-10-2018 HW35_10160 5b5e3abee0bb8c60676ba4fa72fc4c7d 338 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 256 332 7.9E-5 T 12-10-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_10160 5b5e3abee0bb8c60676ba4fa72fc4c7d 338 SUPERFAMILY SSF52540 14 195 1.16E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10160 5b5e3abee0bb8c60676ba4fa72fc4c7d 338 Pfam PF13177 DNA polymerase III, delta subunit 15 174 1.1E-56 T 12-10-2018 HW35_10160 5b5e3abee0bb8c60676ba4fa72fc4c7d 338 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 20 202 4.0E-63 T 12-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HW35_16895 db50707761e1a03982abef98f6f5231e 410 PIRSF PIRSF000726 1 63 6.8E-10 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_16895 db50707761e1a03982abef98f6f5231e 410 PIRSF PIRSF000726 58 408 1.0E-91 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_16895 db50707761e1a03982abef98f6f5231e 410 Gene3D G3DSA:3.30.2130.10 256 408 2.9E-34 T 12-10-2018 HW35_16895 db50707761e1a03982abef98f6f5231e 410 SUPERFAMILY SSF53633 2 246 7.33E-69 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_16895 db50707761e1a03982abef98f6f5231e 410 Pfam PF00696 Amino acid kinase family 2 235 1.0E-45 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 HW35_16895 db50707761e1a03982abef98f6f5231e 410 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_16895 db50707761e1a03982abef98f6f5231e 410 SUPERFAMILY SSF55021 260 346 9.16E-16 T 12-10-2018 HW35_16895 db50707761e1a03982abef98f6f5231e 410 Pfam PF13840 ACT domain 335 398 1.3E-20 T 12-10-2018 IPR027795 CASTOR, ACT domain HW35_16895 db50707761e1a03982abef98f6f5231e 410 Gene3D G3DSA:3.40.1160.10 1 255 8.1E-83 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_16895 db50707761e1a03982abef98f6f5231e 410 SUPERFAMILY SSF55021 334 403 6.11E-16 T 12-10-2018 HW35_16895 db50707761e1a03982abef98f6f5231e 410 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 9.1E-140 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_16895 db50707761e1a03982abef98f6f5231e 410 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 68 401 2.4E-93 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HW35_07320 616c69812e80429177649da2bb2b1e0c 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 1.2E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_07320 616c69812e80429177649da2bb2b1e0c 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.2E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_07320 616c69812e80429177649da2bb2b1e0c 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.2E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_07320 616c69812e80429177649da2bb2b1e0c 106 Pfam PF01022 Bacterial regulatory protein, arsR family 19 62 4.0E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_07320 616c69812e80429177649da2bb2b1e0c 106 SMART SM00418 11 85 5.6E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_07320 616c69812e80429177649da2bb2b1e0c 106 Gene3D G3DSA:1.10.10.10 3 100 2.6E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_07320 616c69812e80429177649da2bb2b1e0c 106 SUPERFAMILY SSF46785 1 95 3.04E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_10075 7fc6ac5d4f80608f5f71381263b67f6f 215 PIRSF PIRSF000705 2 209 7.3E-57 T 12-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 HW35_10075 7fc6ac5d4f80608f5f71381263b67f6f 215 SUPERFAMILY SSF52540 1 208 5.3E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10075 7fc6ac5d4f80608f5f71381263b67f6f 215 Gene3D G3DSA:3.40.50.300 5 208 1.3E-48 T 12-10-2018 HW35_10075 7fc6ac5d4f80608f5f71381263b67f6f 215 Pfam PF01712 Deoxynucleoside kinase 7 204 8.6E-49 T 12-10-2018 IPR031314 Deoxynucleoside kinase domain HW35_16220 1d2ca0cde0d5b05cd5300916dc8a4b63 404 Pfam PF05636 HIGH Nucleotidyl Transferase 1 380 1.0E-145 T 12-10-2018 IPR008513 Uncharacterised protein family UPF0348 HW35_16220 1d2ca0cde0d5b05cd5300916dc8a4b63 404 SUPERFAMILY SSF52374 1 243 3.56E-22 T 12-10-2018 HW35_16220 1d2ca0cde0d5b05cd5300916dc8a4b63 404 Gene3D G3DSA:3.40.50.620 1 242 1.3E-40 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_16220 1d2ca0cde0d5b05cd5300916dc8a4b63 404 Hamap MF_01539 UPF0348 protein . 2 401 41.272 T 12-10-2018 IPR008513 Uncharacterised protein family UPF0348 HW35_05555 39d381598a7de85deb414ce221eb434b 88 Pfam PF06961 Protein of unknown function (DUF1294) 13 66 1.3E-24 T 12-10-2018 IPR010718 Protein of unknown function DUF1294 HW35_05825 331d05f8cfd96eeb591adee768415f57 336 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 61 281 9.9E-85 T 12-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 HW35_05825 331d05f8cfd96eeb591adee768415f57 336 Gene3D G3DSA:3.90.226.10 64 278 8.1E-88 T 12-10-2018 HW35_05825 331d05f8cfd96eeb591adee768415f57 336 SUPERFAMILY SSF52096 56 270 1.39E-43 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_05825 331d05f8cfd96eeb591adee768415f57 336 Gene3D G3DSA:3.40.1750.20 173 239 8.1E-88 T 12-10-2018 HW35_05825 331d05f8cfd96eeb591adee768415f57 336 Pfam PF01343 Peptidase family S49 132 283 2.6E-58 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 HW35_00575 4b776571541212c4b15a0ce1aed28a3e 208 SUPERFAMILY SSF48498 116 201 1.46E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily HW35_00575 4b776571541212c4b15a0ce1aed28a3e 208 SUPERFAMILY SSF46689 16 83 1.4E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_00575 4b776571541212c4b15a0ce1aed28a3e 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 40 71 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HW35_00575 4b776571541212c4b15a0ce1aed28a3e 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 9.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_00575 4b776571541212c4b15a0ce1aed28a3e 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 9.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_00575 4b776571541212c4b15a0ce1aed28a3e 208 Gene3D G3DSA:1.10.357.10 13 195 1.3E-30 T 12-10-2018 HW35_00575 4b776571541212c4b15a0ce1aed28a3e 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 71 8.2E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_16520 5dd0a1b9c035adfdf1038388e5804f0b 291 Pfam PF03755 YicC-like family, N-terminal region 3 156 5.0E-39 T 12-10-2018 IPR013527 YicC-like, N-terminal HW35_16520 5dd0a1b9c035adfdf1038388e5804f0b 291 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 291 9.1E-82 T 12-10-2018 IPR005229 Conserved hypothetical protein CHP00255 HW35_16520 5dd0a1b9c035adfdf1038388e5804f0b 291 Pfam PF08340 Domain of unknown function (DUF1732) 207 291 1.4E-36 T 12-10-2018 IPR013551 Domain of unknown function DUF1732 HW35_12725 870538a7e672dede7ed4e85de23a9f33 70 SUPERFAMILY SSF47413 3 69 5.35E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_12725 870538a7e672dede7ed4e85de23a9f33 70 SMART SM00530 13 68 2.6E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_12725 870538a7e672dede7ed4e85de23a9f33 70 Gene3D G3DSA:1.10.260.40 1 70 2.8E-17 T 12-10-2018 HW35_12725 870538a7e672dede7ed4e85de23a9f33 70 Pfam PF01381 Helix-turn-helix 14 68 2.6E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 Gene3D G3DSA:3.90.1440.10 227 348 0.0 T 12-10-2018 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 Pfam PF07516 SecA Wing and Scaffold domain 568 778 1.0E-64 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 Gene3D G3DSA:1.10.1200.230 621 705 0.0 T 12-10-2018 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 781 19.973 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 PRINTS PR00906 SecA protein signature 393 406 1.1E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 PRINTS PR00906 SecA protein signature 61 85 1.1E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 PRINTS PR00906 SecA protein signature 115 125 1.1E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 PRINTS PR00906 SecA protein signature 356 373 1.1E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 PRINTS PR00906 SecA protein signature 99 113 1.1E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 PRINTS PR00906 SecA protein signature 168 188 1.1E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 PRINTS PR00906 SecA protein signature 319 341 1.1E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 ProSitePatterns PS01312 SecA family signature. 480 495 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 Gene3D G3DSA:3.40.50.300 397 570 0.0 T 12-10-2018 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 SUPERFAMILY SSF81886 571 826 1.01E-80 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 SUPERFAMILY SSF81767 225 348 1.18E-49 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 1.0E-246 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 SUPERFAMILY SSF52540 397 569 9.7E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 Pfam PF07517 SecA DEAD-like domain 6 382 1.9E-130 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 Pfam PF01043 SecA preprotein cross-linking domain 230 338 1.4E-43 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 Gene3D G3DSA:1.10.3060.10 571 777 0.0 T 12-10-2018 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 SMART SM00957 5 382 1.8E-290 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 SMART SM00958 226 338 3.0E-72 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 Gene3D G3DSA:3.40.50.300 14 396 0.0 T 12-10-2018 HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 SUPERFAMILY SSF52540 5 395 7.89E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07860 3943224e1f3bde4a4ffc95974433fa46 838 Pfam PF02810 SEC-C motif 818 835 1.1E-9 T 12-10-2018 IPR004027 SEC-C motif HW35_15975 2813c63f4cba31eb72d274d3cceeeca5 91 PIRSF PIRSF037260 1 91 1.3E-39 T 12-10-2018 IPR007920 Protein of unknown function UPF0223 HW35_15975 2813c63f4cba31eb72d274d3cceeeca5 91 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 3 89 5.0E-26 T 12-10-2018 IPR007920 Protein of unknown function UPF0223 HW35_15975 2813c63f4cba31eb72d274d3cceeeca5 91 SUPERFAMILY SSF158504 4 84 8.89E-35 T 12-10-2018 IPR023324 BH2638-like superfamily HW35_15975 2813c63f4cba31eb72d274d3cceeeca5 91 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 83 4.8E-39 T 12-10-2018 IPR007920 Protein of unknown function UPF0223 HW35_15975 2813c63f4cba31eb72d274d3cceeeca5 91 Hamap MF_01041 UPF0223 protein . 1 89 26.469 T 12-10-2018 IPR007920 Protein of unknown function UPF0223 HW35_15975 2813c63f4cba31eb72d274d3cceeeca5 91 Gene3D G3DSA:1.10.220.80 12 90 1.7E-31 T 12-10-2018 IPR023324 BH2638-like superfamily HW35_07830 f67b7a803248def15fffa2d70275719f 297 Pfam PF02687 FtsX-like permease family 200 290 3.4E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HW35_07830 f67b7a803248def15fffa2d70275719f 297 PIRSF PIRSF003097 1 297 1.2E-87 T 12-10-2018 IPR004513 Cell division protein FtsX GO:0016021 HW35_07830 f67b7a803248def15fffa2d70275719f 297 Gene3D G3DSA:3.30.70.3040 49 156 7.9E-7 T 12-10-2018 HW35_12395 210be8c85597c181519bef646616d9ac 242 SUPERFAMILY SSF52540 1 234 9.76E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12395 210be8c85597c181519bef646616d9ac 242 SMART SM00382 26 213 4.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_12395 210be8c85597c181519bef646616d9ac 242 Gene3D G3DSA:3.40.50.300 1 240 1.5E-80 T 12-10-2018 HW35_12395 210be8c85597c181519bef646616d9ac 242 Pfam PF00005 ABC transporter 17 165 3.1E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12395 210be8c85597c181519bef646616d9ac 242 PIRSF PIRSF039085 1 241 1.1E-118 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HW35_12395 210be8c85597c181519bef646616d9ac 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 3.1E-78 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 389 408 3.1E-78 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 3.1E-78 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 363 385 3.1E-78 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 3.1E-78 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 3.1E-78 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 3.1E-78 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 3.1E-78 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 SUPERFAMILY SSF144052 4 410 2.09E-159 T 12-10-2018 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 Pfam PF02073 Thermophilic metalloprotease (M29) 4 408 5.4E-185 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 HW35_13640 11489fe5cb2bc30dd408100da8f94f3c 410 Gene3D G3DSA:3.40.1830.10 1 180 3.1E-72 T 12-10-2018 IPR035097 Peptidase M29, N-terminal HW35_17425 90e8b949b8a0c7fc37eb321b6c0c734a 182 SMART SM00855 2 148 5.1E-10 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HW35_17425 90e8b949b8a0c7fc37eb321b6c0c734a 182 Gene3D G3DSA:3.40.50.1240 1 178 2.1E-33 T 12-10-2018 IPR029033 Histidine phosphatase superfamily HW35_17425 90e8b949b8a0c7fc37eb321b6c0c734a 182 SUPERFAMILY SSF53254 1 171 7.71E-33 T 12-10-2018 IPR029033 Histidine phosphatase superfamily HW35_17425 90e8b949b8a0c7fc37eb321b6c0c734a 182 PIRSF PIRSF000709 11 180 9.1E-6 T 12-10-2018 HW35_17425 90e8b949b8a0c7fc37eb321b6c0c734a 182 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 170 2.1E-26 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HW35_06690 afaabd8b3d894d097f0ca49d87346d51 127 Gene3D G3DSA:3.10.180.10 1 127 6.2E-33 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_06690 afaabd8b3d894d097f0ca49d87346d51 127 SUPERFAMILY SSF54593 4 127 1.22E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_06690 afaabd8b3d894d097f0ca49d87346d51 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 124 3.6E-16 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HW35_02925 1d9160bc44e2d160217d87b5ec59039a 563 Gene3D G3DSA:3.10.410.10 450 539 8.3E-36 T 12-10-2018 HW35_02925 1d9160bc44e2d160217d87b5ec59039a 563 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 334 345 - T 12-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HW35_02925 1d9160bc44e2d160217d87b5ec59039a 563 Gene3D G3DSA:3.30.1510.10 135 253 1.7E-203 T 12-10-2018 HW35_02925 1d9160bc44e2d160217d87b5ec59039a 563 SUPERFAMILY SSF52540 10 561 3.72E-244 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02925 1d9160bc44e2d160217d87b5ec59039a 563 Gene3D G3DSA:3.40.50.300 12 445 1.7E-203 T 12-10-2018 HW35_02925 1d9160bc44e2d160217d87b5ec59039a 563 Pfam PF01268 Formate--tetrahydrofolate ligase 8 563 1.7E-269 T 12-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HW35_02925 1d9160bc44e2d160217d87b5ec59039a 563 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 109 119 - T 12-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HW35_02925 1d9160bc44e2d160217d87b5ec59039a 563 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 7 563 48.995 T 12-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HW35_13550 2fa5d0502e4900bdc454b1a682011461 192 Gene3D G3DSA:2.60.40.1220 25 116 2.5E-26 T 12-10-2018 HW35_13550 2fa5d0502e4900bdc454b1a682011461 192 Pfam PF04234 CopC domain 23 115 2.3E-18 T 12-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 HW35_13550 2fa5d0502e4900bdc454b1a682011461 192 SUPERFAMILY SSF81296 22 115 2.66E-18 T 12-10-2018 IPR014756 Immunoglobulin E-set HW35_07275 83aec17cd2e2a7e72359ca48c13ae288 335 Pfam PF01594 AI-2E family transporter 14 328 1.9E-46 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 Pfam PF00271 Helicase conserved C-terminal domain 216 323 2.7E-18 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 SMART SM00956 404 507 7.8E-41 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 8 583 6.3E-237 T 12-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 Gene3D G3DSA:1.10.10.10 334 510 1.6E-47 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 SMART SM00341 512 592 7.9E-16 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 Pfam PF00270 DEAD/DEAH box helicase 21 182 2.0E-21 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 SMART SM00487 14 211 2.7E-30 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 SMART SM00490 243 324 5.2E-26 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 Gene3D G3DSA:1.10.150.80 511 592 1.7E-25 T 12-10-2018 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 Pfam PF00570 HRDC domain 517 582 1.8E-20 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 SUPERFAMILY SSF46785 395 537 2.31E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 457 3.8E-146 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 Pfam PF09382 RQC domain 401 507 8.8E-31 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 Pfam PF14493 Helix-turn-helix domain 613 701 1.6E-25 T 12-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 SUPERFAMILY SSF47819 512 590 4.58E-25 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 SUPERFAMILY SSF52540 58 346 6.79E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 Gene3D G3DSA:3.40.50.300 202 333 4.6E-39 T 12-10-2018 HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 Pfam PF16124 RecQ zinc-binding 335 396 1.6E-16 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain HW35_13375 5f76a02e2409710b0c57e6d9782ab5d8 707 Gene3D G3DSA:3.40.50.300 2 201 4.0E-77 T 12-10-2018 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 Gene3D G3DSA:3.40.630.10 105 395 7.5E-54 T 12-10-2018 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 Gene3D G3DSA:3.10.350.10 2 46 1.6E-7 T 12-10-2018 IPR036779 LysM domain superfamily HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 Gene3D G3DSA:3.10.350.10 50 96 5.6E-15 T 12-10-2018 IPR036779 LysM domain superfamily HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 Pfam PF00246 Zinc carboxypeptidase 118 337 7.5E-32 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 250 258 3.5E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 134 146 3.5E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 153 167 3.5E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 304 317 3.5E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 Pfam PF01476 LysM domain 4 46 6.8E-6 T 12-10-2018 IPR018392 LysM domain HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 Pfam PF01476 LysM domain 53 96 8.4E-10 T 12-10-2018 IPR018392 LysM domain HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 SMART SM00257 52 96 1.1E-12 T 12-10-2018 IPR018392 LysM domain HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 SMART SM00257 2 46 1.2E-7 T 12-10-2018 IPR018392 LysM domain HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 SUPERFAMILY SSF53187 108 393 9.08E-57 T 12-10-2018 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 SUPERFAMILY SSF54106 4 46 4.97E-5 T 12-10-2018 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 SUPERFAMILY SSF54106 52 96 4.19E-9 T 12-10-2018 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 SMART SM00631 109 385 7.8E-28 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HW35_11310 f89fe2439d5ac4abb402f01c22a1403f 396 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 153 175 - T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 SUPERFAMILY SSF56059 1 378 1.29E-148 T 12-10-2018 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 Pfam PF00391 PEP-utilising enzyme, mobile domain 419 500 4.7E-27 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 SUPERFAMILY SSF51621 508 877 1.54E-126 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 447 458 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 PIRSF PIRSF000853 1 884 0.0 T 12-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 515 874 8.6E-96 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 SUPERFAMILY SSF52009 386 509 3.14E-38 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 765 783 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 Gene3D G3DSA:3.30.470.20 243 340 1.3E-43 T 12-10-2018 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 Gene3D G3DSA:3.30.1490.20 10 242 4.4E-103 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 302 8.1E-49 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 876 0.0 T 12-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 Gene3D G3DSA:1.20.80.30 110 197 4.4E-103 T 12-10-2018 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 Gene3D G3DSA:1.10.189.10 344 526 6.7E-78 T 12-10-2018 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 Gene3D G3DSA:3.50.30.10 382 506 6.7E-78 T 12-10-2018 HW35_02015 9386f6af95411fdd934aad9faa89615c 889 Gene3D G3DSA:3.20.20.60 529 879 3.3E-149 T 12-10-2018 HW35_16400 39bbca3c55d37b45246de70561e17f62 86 Pfam PF05239 PRC-barrel domain 3 76 5.2E-12 T 12-10-2018 IPR027275 PRC-barrel domain HW35_16400 39bbca3c55d37b45246de70561e17f62 86 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 4 74 9.3E-26 T 12-10-2018 IPR014238 Sporulation protein YlmC/YmxH HW35_16400 39bbca3c55d37b45246de70561e17f62 86 Gene3D G3DSA:2.30.30.240 2 77 9.2E-12 T 12-10-2018 HW35_16400 39bbca3c55d37b45246de70561e17f62 86 SUPERFAMILY SSF50346 2 75 1.26E-13 T 12-10-2018 IPR011033 PRC-barrel-like superfamily HW35_10340 62b61ea93285fe872925687d9b4a0122 245 Pfam PF00092 von Willebrand factor type A domain 9 74 1.1E-5 T 12-10-2018 IPR002035 von Willebrand factor, type A HW35_10340 62b61ea93285fe872925687d9b4a0122 245 Gene3D G3DSA:3.40.50.410 2 238 8.9E-61 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily HW35_10340 62b61ea93285fe872925687d9b4a0122 245 SUPERFAMILY SSF53300 3 69 2.7E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily HW35_10340 62b61ea93285fe872925687d9b4a0122 245 SUPERFAMILY SSF53300 132 225 2.23E-13 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily HW35_10340 62b61ea93285fe872925687d9b4a0122 245 Pfam PF13519 von Willebrand factor type A domain 135 227 1.5E-8 T 12-10-2018 IPR002035 von Willebrand factor, type A HW35_08590 badde490d39b9fab256d946048eb4a5f 159 SUPERFAMILY SSF88946 3 72 1.57E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_08590 badde490d39b9fab256d946048eb4a5f 159 Gene3D G3DSA:1.10.1740.10 2 70 1.8E-8 T 12-10-2018 HW35_08590 badde490d39b9fab256d946048eb4a5f 159 Gene3D G3DSA:1.10.10.10 87 158 9.6E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_08590 badde490d39b9fab256d946048eb4a5f 159 Pfam PF08281 Sigma-70, region 4 109 152 2.6E-7 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HW35_08590 badde490d39b9fab256d946048eb4a5f 159 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 154 3.3E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_08590 badde490d39b9fab256d946048eb4a5f 159 Pfam PF04542 Sigma-70 region 2 8 73 3.2E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_08590 badde490d39b9fab256d946048eb4a5f 159 SUPERFAMILY SSF88659 107 158 5.79E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 SUPERFAMILY SSF53067 144 328 4.32E-46 T 12-10-2018 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 4 331 2.2E-136 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 Gene3D G3DSA:3.30.420.40 7 322 3.8E-123 T 12-10-2018 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 Gene3D G3DSA:3.90.640.10 181 254 3.8E-123 T 12-10-2018 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 SUPERFAMILY SSF53067 4 143 2.3E-40 T 12-10-2018 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 Gene3D G3DSA:3.30.420.40 149 312 3.8E-123 T 12-10-2018 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 Pfam PF06723 MreB/Mbl protein 5 331 7.3E-142 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 182 202 1.2E-54 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 127 146 1.2E-54 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 1.2E-54 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 1.2E-54 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_17135 a064ef66d52b72d79abcbc4bddded723 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 1.2E-54 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 449 1.8E-64 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 493 1.8E-227 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 251 2.6E-86 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 SUPERFAMILY SSF53067 254 492 6.73E-85 T 12-10-2018 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 Gene3D G3DSA:3.30.420.40 253 496 4.3E-91 T 12-10-2018 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 PIRSF PIRSF000538 2 496 1.5E-181 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 Gene3D G3DSA:3.30.420.40 1 252 1.8E-111 T 12-10-2018 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 59.525 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 SUPERFAMILY SSF53067 4 254 6.6E-95 T 12-10-2018 HW35_15780 076ff3660c2eb51f5b1b73cdef66446d 496 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HW35_04880 0fcd317f0d68d0551133f3140c748278 423 Pfam PF03129 Anticodon binding domain 331 420 5.9E-17 T 12-10-2018 IPR004154 Anticodon-binding HW35_04880 0fcd317f0d68d0551133f3140c748278 423 Gene3D G3DSA:3.30.930.10 2 326 1.3E-116 T 12-10-2018 HW35_04880 0fcd317f0d68d0551133f3140c748278 423 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 421 33.948 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 HW35_04880 0fcd317f0d68d0551133f3140c748278 423 Gene3D G3DSA:3.40.50.800 329 423 2.1E-26 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily HW35_04880 0fcd317f0d68d0551133f3140c748278 423 SUPERFAMILY SSF55681 4 318 3.06E-96 T 12-10-2018 HW35_04880 0fcd317f0d68d0551133f3140c748278 423 SUPERFAMILY SSF52954 329 420 2.72E-25 T 12-10-2018 HW35_04880 0fcd317f0d68d0551133f3140c748278 423 Pfam PF13393 Histidyl-tRNA synthetase 8 312 4.0E-46 T 12-10-2018 HW35_04880 0fcd317f0d68d0551133f3140c748278 423 PIRSF PIRSF001549 1 420 2.6E-120 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 HW35_04880 0fcd317f0d68d0551133f3140c748278 423 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 410 9.9E-157 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 HW35_14315 03fe24090e7ec5f049b78c1be7b7f2b3 183 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 174 4.0E-54 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 HW35_14315 03fe24090e7ec5f049b78c1be7b7f2b3 183 Pfam PF01923 Cobalamin adenosyltransferase 3 169 1.8E-60 T 12-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 HW35_14315 03fe24090e7ec5f049b78c1be7b7f2b3 183 SUPERFAMILY SSF89028 1 178 2.35E-58 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 HW35_14315 03fe24090e7ec5f049b78c1be7b7f2b3 183 Gene3D G3DSA:1.20.1200.10 12 183 1.4E-60 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 HW35_14315 03fe24090e7ec5f049b78c1be7b7f2b3 183 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 178 1.1E-54 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 HW35_06940 20bc0f395edabcd6257a10b0310d5152 79 Hamap MF_01542 UPF0349 protein . 2 78 29.561 T 12-10-2018 IPR022916 Protein of unknown function UPF0349 HW35_06940 20bc0f395edabcd6257a10b0310d5152 79 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 4 78 7.0E-28 T 12-10-2018 HW35_06940 20bc0f395edabcd6257a10b0310d5152 79 Pfam PF07293 Protein of unknown function (DUF1450) 2 76 1.1E-35 T 12-10-2018 IPR009910 Protein of unknown function DUF1450 HW35_17195 e160651f8f54ffd3c5b831fb23952678 76 SUPERFAMILY SSF158221 1 42 4.45E-14 T 12-10-2018 HW35_17195 e160651f8f54ffd3c5b831fb23952678 76 Hamap MF_01103 UPF0291 protein . 2 60 15.612 T 12-10-2018 IPR009242 Protein of unknown function DUF896 HW35_17195 e160651f8f54ffd3c5b831fb23952678 76 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 68 2.3E-30 T 12-10-2018 IPR009242 Protein of unknown function DUF896 HW35_17195 e160651f8f54ffd3c5b831fb23952678 76 Gene3D G3DSA:1.10.287.540 1 56 2.5E-22 T 12-10-2018 HW35_09315 43825c7b6c2615571b3bb031792ec880 137 SUPERFAMILY SSF50814 2 133 5.32E-29 T 12-10-2018 IPR012674 Calycin HW35_09315 43825c7b6c2615571b3bb031792ec880 137 Pfam PF09148 Domain of unknown function (DUF1934) 7 129 2.4E-29 T 12-10-2018 IPR015231 Protein of unknown function DUF1934 HW35_09315 43825c7b6c2615571b3bb031792ec880 137 Gene3D G3DSA:2.40.128.20 1 136 1.0E-40 T 12-10-2018 IPR012674 Calycin HW35_05875 d9541238f3f6072dcdbe556f0d56ba9f 394 SUPERFAMILY SSF53383 27 393 1.88E-121 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_05875 d9541238f3f6072dcdbe556f0d56ba9f 394 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 7 393 2.3E-186 T 12-10-2018 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2|MetaCyc: PWY-7793 HW35_05875 d9541238f3f6072dcdbe556f0d56ba9f 394 Gene3D G3DSA:3.40.640.10 4 257 2.5E-94 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_05875 d9541238f3f6072dcdbe556f0d56ba9f 394 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 392 4.1E-148 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_05875 d9541238f3f6072dcdbe556f0d56ba9f 394 Gene3D G3DSA:3.90.1150.10 260 394 2.6E-52 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_05875 d9541238f3f6072dcdbe556f0d56ba9f 394 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_05875 d9541238f3f6072dcdbe556f0d56ba9f 394 PIRSF PIRSF001434 1 394 9.2E-147 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 246 1.6E-111 T 12-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 3.5E-75 T 12-10-2018 HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 4.6E-6 T 12-10-2018 HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 SUPERFAMILY SSF51735 5 247 6.2E-96 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.2E-51 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.2E-51 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.2E-51 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.2E-51 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.2E-51 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.2E-51 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.0E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.0E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.0E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HW35_16645 9955281d679e1f89c13536e1c2643a3d 247 Gene3D G3DSA:3.40.50.720 4 247 6.4E-94 T 12-10-2018 HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 Gene3D G3DSA:3.40.800.10 2 299 2.2E-117 T 12-10-2018 HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 PIRSF PIRSF036979 1 296 1.7E-37 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 ProSitePatterns PS01053 Arginase family signature. 224 245 - T 12-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 SUPERFAMILY SSF52768 4 296 2.16E-95 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 Pfam PF00491 Arginase family 4 294 2.5E-80 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 PRINTS PR00116 Arginase signature 172 190 2.2E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 PRINTS PR00116 Arginase signature 95 110 2.2E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 PRINTS PR00116 Arginase signature 118 145 2.2E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 PRINTS PR00116 Arginase signature 256 270 2.2E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 PRINTS PR00116 Arginase signature 221 250 2.2E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_11060 37151e25c7d7622cf9953fa97c424cef 299 TIGRFAM TIGR01229 rocF_arginase: arginase 6 299 1.4E-106 T 12-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 HW35_00535 6f4cf0a28ca4a9fd7638ce34d3704bc1 410 SMART SM00962 216 407 4.7E-47 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_00535 6f4cf0a28ca4a9fd7638ce34d3704bc1 410 SUPERFAMILY SSF52540 215 407 1.06E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_00535 6f4cf0a28ca4a9fd7638ce34d3704bc1 410 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 303 3.5E-68 T 12-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 HW35_00535 6f4cf0a28ca4a9fd7638ce34d3704bc1 410 Pfam PF00448 SRP54-type protein, GTPase domain 218 405 1.3E-37 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_00535 6f4cf0a28ca4a9fd7638ce34d3704bc1 410 Gene3D G3DSA:3.40.50.300 211 395 5.6E-75 T 12-10-2018 HW35_00535 6f4cf0a28ca4a9fd7638ce34d3704bc1 410 Gene3D G3DSA:1.20.120.1380 158 398 5.6E-75 T 12-10-2018 HW35_14020 dbfbe8476034a1a63e3c63466abeafbf 343 Pfam PF01867 CRISPR associated protein Cas1 8 297 4.9E-101 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HW35_14020 dbfbe8476034a1a63e3c63466abeafbf 343 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 7 337 1.0E-94 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HW35_14020 dbfbe8476034a1a63e3c63466abeafbf 343 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 328 26.914 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HW35_14020 dbfbe8476034a1a63e3c63466abeafbf 343 Gene3D G3DSA:1.20.120.920 86 342 1.6E-77 T 12-10-2018 HW35_14020 dbfbe8476034a1a63e3c63466abeafbf 343 Gene3D G3DSA:3.100.10.20 6 83 1.6E-17 T 12-10-2018 HW35_14020 dbfbe8476034a1a63e3c63466abeafbf 343 TIGRFAM TIGR03640 cas1_DVULG: CRISPR-associated endonuclease Cas1, subtype I-C/DVULG 3 342 1.7E-149 T 12-10-2018 IPR019856 CRISPR-associated protein Cas1, DVULG subtype GO:0004520|GO:0043571|GO:0046872 HW35_03825 13ade33e3fca9ec535d93321ce9a0727 425 Pfam PF11799 impB/mucB/samB family C-terminal domain 251 353 5.6E-19 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HW35_03825 13ade33e3fca9ec535d93321ce9a0727 425 Gene3D G3DSA:2.30.40.20 29 82 1.1E-61 T 12-10-2018 HW35_03825 13ade33e3fca9ec535d93321ce9a0727 425 Gene3D G3DSA:3.30.1490.100 251 358 5.7E-24 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HW35_03825 13ade33e3fca9ec535d93321ce9a0727 425 Gene3D G3DSA:3.30.70.270 12 172 1.1E-61 T 12-10-2018 HW35_03825 13ade33e3fca9ec535d93321ce9a0727 425 SUPERFAMILY SSF56672 7 242 1.78E-86 T 12-10-2018 HW35_03825 13ade33e3fca9ec535d93321ce9a0727 425 Hamap MF_01113 DNA polymerase IV [dinB]. 9 361 38.963 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 HW35_03825 13ade33e3fca9ec535d93321ce9a0727 425 Pfam PF11798 IMS family HHH motif 176 205 1.4E-6 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 HW35_03825 13ade33e3fca9ec535d93321ce9a0727 425 Pfam PF00817 impB/mucB/samB family 15 162 1.5E-52 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HW35_03825 13ade33e3fca9ec535d93321ce9a0727 425 Gene3D G3DSA:1.10.150.20 177 243 5.5E-15 T 12-10-2018 HW35_03825 13ade33e3fca9ec535d93321ce9a0727 425 SUPERFAMILY SSF100879 250 345 7.26E-24 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HW35_16925 acab48efcd1f489c9d6cfaa00c45b5d5 241 Gene3D G3DSA:1.10.10.10 3 74 2.2E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_16925 acab48efcd1f489c9d6cfaa00c45b5d5 241 Pfam PF07702 UTRA domain 96 233 2.7E-30 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HW35_16925 acab48efcd1f489c9d6cfaa00c45b5d5 241 SMART SM00345 14 73 5.2E-23 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_16925 acab48efcd1f489c9d6cfaa00c45b5d5 241 Gene3D G3DSA:3.40.1410.10 77 238 2.3E-32 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily HW35_16925 acab48efcd1f489c9d6cfaa00c45b5d5 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.3E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_16925 acab48efcd1f489c9d6cfaa00c45b5d5 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.3E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_16925 acab48efcd1f489c9d6cfaa00c45b5d5 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 2.1E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_16925 acab48efcd1f489c9d6cfaa00c45b5d5 241 SUPERFAMILY SSF46785 5 84 7.91E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_16925 acab48efcd1f489c9d6cfaa00c45b5d5 241 SUPERFAMILY SSF64288 62 240 4.24E-39 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily HW35_16925 acab48efcd1f489c9d6cfaa00c45b5d5 241 SMART SM00866 95 233 1.5E-26 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HW35_16885 a78e7f0e5741d35e7e093e6b5838b0ca 199 Gene3D G3DSA:3.40.50.1950 1 199 1.7E-57 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 HW35_16885 a78e7f0e5741d35e7e093e6b5838b0ca 199 PIRSF PIRSF001390 1 195 4.8E-81 T 12-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B HW35_16885 a78e7f0e5741d35e7e093e6b5838b0ca 199 Pfam PF02441 Flavoprotein 6 169 3.9E-16 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 HW35_16885 a78e7f0e5741d35e7e093e6b5838b0ca 199 SUPERFAMILY SSF52507 6 192 1.44E-26 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 HW35_16885 a78e7f0e5741d35e7e093e6b5838b0ca 199 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 2.3E-101 T 12-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B HW35_07800 2b5783ce2fe8bdfd1687bfd0bc22c28a 248 Gene3D G3DSA:3.40.50.300 1 248 2.2E-78 T 12-10-2018 HW35_07800 2b5783ce2fe8bdfd1687bfd0bc22c28a 248 SMART SM00382 28 220 2.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_07800 2b5783ce2fe8bdfd1687bfd0bc22c28a 248 PIRSF PIRSF039085 1 248 5.7E-111 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HW35_07800 2b5783ce2fe8bdfd1687bfd0bc22c28a 248 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_07800 2b5783ce2fe8bdfd1687bfd0bc22c28a 248 Pfam PF00005 ABC transporter 19 172 7.8E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_07800 2b5783ce2fe8bdfd1687bfd0bc22c28a 248 SUPERFAMILY SSF52540 3 242 2.15E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15185 d600a40e55407efb30696592260059d6 112 SUPERFAMILY SSF75169 13 105 6.06E-15 T 12-10-2018 IPR027396 DsrEFH-like HW35_15185 d600a40e55407efb30696592260059d6 112 Pfam PF02635 DsrE/DsrF-like family 36 109 9.8E-9 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein HW35_15185 d600a40e55407efb30696592260059d6 112 Gene3D G3DSA:3.40.1260.10 17 110 2.5E-8 T 12-10-2018 IPR027396 DsrEFH-like HW35_12520 e753f4c195a245980b253699030856e6 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 318 4.4E-51 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 HW35_16905 083758065830e2991c455ddc6fc8e618 555 PIRSF PIRSF004803 1 555 1.6E-219 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HW35_16905 083758065830e2991c455ddc6fc8e618 555 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 4.1E-18 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_16905 083758065830e2991c455ddc6fc8e618 555 Gene3D G3DSA:3.60.15.10 10 436 3.5E-170 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_16905 083758065830e2991c455ddc6fc8e618 555 SUPERFAMILY SSF56281 9 423 1.09E-90 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_16905 083758065830e2991c455ddc6fc8e618 555 SMART SM00849 21 214 2.1E-27 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_16905 083758065830e2991c455ddc6fc8e618 555 Gene3D G3DSA:3.10.20.580 449 555 5.1E-38 T 12-10-2018 HW35_16905 083758065830e2991c455ddc6fc8e618 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 44.729 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HW35_16905 083758065830e2991c455ddc6fc8e618 555 Gene3D G3DSA:3.40.50.10710 208 365 3.5E-170 T 12-10-2018 HW35_16905 083758065830e2991c455ddc6fc8e618 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 553 6.1E-200 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 HW35_16905 083758065830e2991c455ddc6fc8e618 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 356 402 4.4E-10 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain HW35_07120 e9580dbdfd1ea9cf3951f7743a9d086f 102 SUPERFAMILY SSF52833 6 100 1.48E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_07120 e9580dbdfd1ea9cf3951f7743a9d086f 102 Gene3D G3DSA:3.40.30.10 4 100 7.7E-13 T 12-10-2018 HW35_07120 e9580dbdfd1ea9cf3951f7743a9d086f 102 Pfam PF00085 Thioredoxin 16 99 4.9E-11 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 HW35_00225 74a6f4b7a7848148ba38dd4c081ac8ec 312 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 149 4.8E-39 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G HW35_00225 74a6f4b7a7848148ba38dd4c081ac8ec 312 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site HW35_00225 74a6f4b7a7848148ba38dd4c081ac8ec 312 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 227 310 6.4E-22 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HW35_00225 74a6f4b7a7848148ba38dd4c081ac8ec 312 Pfam PF00460 Flagella basal body rod protein 5 35 3.9E-12 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HW35_00225 74a6f4b7a7848148ba38dd4c081ac8ec 312 SUPERFAMILY SSF117143 92 272 3.92E-22 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 290 2.8E-92 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 139 8.7E-38 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 Gene3D G3DSA:3.40.50.1370 6 288 7.5E-94 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 Gene3D G3DSA:3.40.50.1370 127 271 7.5E-94 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 245 254 2.0E-21 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 280 2.0E-21 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 2.0E-21 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 2.0E-21 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 SUPERFAMILY SSF53671 2 293 1.44E-89 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 294 37.909 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 249 254 9.3E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 273 287 9.3E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 9.3E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 9.3E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 208 217 9.3E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 9.3E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16470 d9c0f8de6d8248d9321adbf42c0ea29e 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 288 7.6E-21 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 HW35_09325 b04874353bd22023e2be076d4b7fedf4 276 Pfam PF01564 Spermine/spermidine synthase domain 59 237 1.8E-70 T 12-10-2018 HW35_09325 b04874353bd22023e2be076d4b7fedf4 276 TIGRFAM TIGR00417 speE: spermidine synthase 5 270 2.7E-122 T 12-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HW35_09325 b04874353bd22023e2be076d4b7fedf4 276 Gene3D G3DSA:2.30.140.10 2 53 8.6E-25 T 12-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HW35_09325 b04874353bd22023e2be076d4b7fedf4 276 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 80 93 - T 12-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HW35_09325 b04874353bd22023e2be076d4b7fedf4 276 Pfam PF17284 Spermidine synthase tetramerisation domain 4 54 4.7E-20 T 12-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HW35_09325 b04874353bd22023e2be076d4b7fedf4 276 SUPERFAMILY SSF53335 3 275 9.83E-88 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_09325 b04874353bd22023e2be076d4b7fedf4 276 Gene3D G3DSA:3.40.50.150 54 275 2.5E-76 T 12-10-2018 HW35_09325 b04874353bd22023e2be076d4b7fedf4 276 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 4 276 41.535 T 12-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HW35_10395 affbb7363d081cf9253aeef0d5f3593d 119 Pfam PF02152 Dihydroneopterin aldolase 4 116 5.1E-36 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 HW35_10395 affbb7363d081cf9253aeef0d5f3593d 119 SUPERFAMILY SSF55620 2 119 6.12E-40 T 12-10-2018 HW35_10395 affbb7363d081cf9253aeef0d5f3593d 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 1.2E-44 T 12-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 HW35_10395 affbb7363d081cf9253aeef0d5f3593d 119 SMART SM00905 4 117 6.0E-51 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 HW35_10395 affbb7363d081cf9253aeef0d5f3593d 119 TIGRFAM TIGR00526 folB_dom: FolB domain 2 119 3.5E-38 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 HW35_10395 affbb7363d081cf9253aeef0d5f3593d 119 Gene3D G3DSA:3.30.1130.10 1 119 3.8E-46 T 12-10-2018 HW35_17210 788fb8e48e6d6cd5f307fd2a572eeb1e 146 Gene3D G3DSA:3.30.310.250 1 146 4.9E-49 T 12-10-2018 IPR038449 SirA superfamily HW35_17210 788fb8e48e6d6cd5f307fd2a572eeb1e 146 Pfam PF10747 Sporulation inhibitor of replication protein SirA 2 141 1.9E-39 T 12-10-2018 IPR019683 Sporulation inhibitor of replication protein SirA HW35_06015 29778c2de31d1fdc50391d35f72ecec5 310 SUPERFAMILY SSF53686 1 307 1.17E-100 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HW35_06015 29778c2de31d1fdc50391d35f72ecec5 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 307 2.1E-135 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 HW35_06015 29778c2de31d1fdc50391d35f72ecec5 310 Gene3D G3DSA:3.40.50.1100 45 144 1.2E-120 T 12-10-2018 HW35_06015 29778c2de31d1fdc50391d35f72ecec5 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 307 1.4E-127 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 HW35_06015 29778c2de31d1fdc50391d35f72ecec5 310 Gene3D G3DSA:3.40.50.1100 6 303 1.2E-120 T 12-10-2018 HW35_06015 29778c2de31d1fdc50391d35f72ecec5 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 296 7.1E-71 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HW35_06015 29778c2de31d1fdc50391d35f72ecec5 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 HW35_03375 453c7411e8140bf8d00f2f7c21bf039c 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 HW35_03375 453c7411e8140bf8d00f2f7c21bf039c 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.0E-21 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HW35_03375 453c7411e8140bf8d00f2f7c21bf039c 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.0E-21 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HW35_03375 453c7411e8140bf8d00f2f7c21bf039c 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.0E-21 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HW35_03375 453c7411e8140bf8d00f2f7c21bf039c 90 Gene3D G3DSA:4.10.520.10 1 90 2.6E-41 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 HW35_03375 453c7411e8140bf8d00f2f7c21bf039c 90 SMART SM00411 1 90 3.1E-52 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HW35_03375 453c7411e8140bf8d00f2f7c21bf039c 90 SUPERFAMILY SSF47729 1 90 8.98E-36 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 HW35_03375 453c7411e8140bf8d00f2f7c21bf039c 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.9E-38 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 PIRSF PIRSF003161 2 336 1.2E-119 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 6 335 1.1E-135 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 Gene3D G3DSA:1.10.220.30 105 196 7.1E-34 T 12-10-2018 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 Gene3D G3DSA:1.10.220.30 197 336 2.0E-47 T 12-10-2018 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 SUPERFAMILY SSF48029 116 327 4.05E-68 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 SUPERFAMILY SSF48029 2 101 5.1E-23 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 Gene3D G3DSA:1.10.220.30 3 85 1.0E-21 T 12-10-2018 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 Pfam PF14842 FliG N-terminal domain 6 109 3.9E-37 T 12-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 197 222 5.6E-72 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 274 300 5.6E-72 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 116 139 5.6E-72 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 7 23 5.6E-72 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 250 270 5.6E-72 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 228 248 5.6E-72 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 36 62 5.6E-72 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 Pfam PF14841 FliG middle domain 117 191 1.2E-29 T 12-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain HW35_00480 24afc4c08ca7d4f25b608fe86fd6fec6 336 Pfam PF01706 FliG C-terminal domain 220 326 1.2E-40 T 12-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal HW35_05905 95842cbba545e03c6c3b8e37689d8c21 210 SUPERFAMILY SSF55729 31 117 4.1E-6 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_05905 95842cbba545e03c6c3b8e37689d8c21 210 PIRSF PIRSF021278 2 210 2.1E-87 T 12-10-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 HW35_05905 95842cbba545e03c6c3b8e37689d8c21 210 Gene3D G3DSA:3.40.630.30 1 210 1.6E-86 T 12-10-2018 HW35_16850 1276c8f89073b886734329443590600a 317 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 87 1.9E-7 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HW35_16850 1276c8f89073b886734329443590600a 317 Pfam PF06574 FAD synthetase 19 169 9.7E-50 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 HW35_16850 1276c8f89073b886734329443590600a 317 PIRSF PIRSF004491 5 317 5.4E-107 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 HW35_16850 1276c8f89073b886734329443590600a 317 Gene3D G3DSA:2.40.30.30 190 310 2.7E-44 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 HW35_16850 1276c8f89073b886734329443590600a 317 SUPERFAMILY SSF82114 175 314 1.85E-47 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 HW35_16850 1276c8f89073b886734329443590600a 317 Gene3D G3DSA:3.40.50.620 10 189 2.3E-56 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_16850 1276c8f89073b886734329443590600a 317 Pfam PF01687 Riboflavin kinase 186 310 1.0E-38 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 HW35_16850 1276c8f89073b886734329443590600a 317 SMART SM00904 185 311 4.2E-60 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 HW35_16850 1276c8f89073b886734329443590600a 317 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 310 2.1E-98 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 HW35_16850 1276c8f89073b886734329443590600a 317 SUPERFAMILY SSF52374 20 178 7.32E-32 T 12-10-2018 HW35_03265 683ce782b73651882fd5af9a6e21a185 226 Pfam PF04298 Putative neutral zinc metallopeptidase 4 218 2.7E-92 T 12-10-2018 IPR007395 Putative neutral zinc metallopeptidase HW35_07895 1b27d54a56ef2fcaef46ed69b33681dd 279 SUPERFAMILY SSF82549 1 279 1.62E-98 T 12-10-2018 HW35_07895 1b27d54a56ef2fcaef46ed69b33681dd 279 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 279 1.1E-99 T 12-10-2018 IPR003797 DegV HW35_07895 1b27d54a56ef2fcaef46ed69b33681dd 279 Gene3D G3DSA:3.40.50.10170 1 150 1.4E-55 T 12-10-2018 HW35_07895 1b27d54a56ef2fcaef46ed69b33681dd 279 Gene3D G3DSA:3.30.1180.10 151 279 3.7E-45 T 12-10-2018 HW35_07895 1b27d54a56ef2fcaef46ed69b33681dd 279 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 277 2.0E-106 T 12-10-2018 IPR003797 DegV HW35_13795 25d0c94ab56bdd22343ce957dfe7ca28 137 PIRSF PIRSF021328 1 137 3.6E-46 T 12-10-2018 IPR016787 Uncharacterised conserved protein UCP021328 HW35_13795 25d0c94ab56bdd22343ce957dfe7ca28 137 Pfam PF11208 Protein of unknown function (DUF2992) 3 137 2.1E-43 T 12-10-2018 IPR016787 Uncharacterised conserved protein UCP021328 HW35_10575 fad2f1b66951599e4e8e67d7a3f9e052 356 SUPERFAMILY SSF55931 4 269 1.18E-87 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 HW35_10575 fad2f1b66951599e4e8e67d7a3f9e052 356 ProSitePatterns PS00112 Phosphagen kinase active site signature. 168 174 - T 12-10-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 HW35_10575 fad2f1b66951599e4e8e67d7a3f9e052 356 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 66 254 3.2E-73 T 12-10-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 HW35_10575 fad2f1b66951599e4e8e67d7a3f9e052 356 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 351 39.182 T 12-10-2018 IPR023660 Protein arginine kinase GO:0016775 HW35_10575 fad2f1b66951599e4e8e67d7a3f9e052 356 Gene3D G3DSA:3.30.590.10 9 265 5.3E-73 T 12-10-2018 HW35_08870 bdba6f676821ab9c222013fb25545498 355 SUPERFAMILY SSF54106 26 70 3.53E-12 T 12-10-2018 HW35_08870 bdba6f676821ab9c222013fb25545498 355 SUPERFAMILY SSF54106 97 140 1.31E-11 T 12-10-2018 HW35_08870 bdba6f676821ab9c222013fb25545498 355 Gene3D G3DSA:3.90.1720.10 232 355 1.0E-41 T 12-10-2018 HW35_08870 bdba6f676821ab9c222013fb25545498 355 SUPERFAMILY SSF54001 230 354 5.4E-40 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily HW35_08870 bdba6f676821ab9c222013fb25545498 355 Pfam PF01476 LysM domain 99 140 8.0E-15 T 12-10-2018 IPR018392 LysM domain HW35_08870 bdba6f676821ab9c222013fb25545498 355 Pfam PF01476 LysM domain 172 213 5.4E-17 T 12-10-2018 IPR018392 LysM domain HW35_08870 bdba6f676821ab9c222013fb25545498 355 Pfam PF01476 LysM domain 28 69 1.7E-14 T 12-10-2018 IPR018392 LysM domain HW35_08870 bdba6f676821ab9c222013fb25545498 355 Gene3D G3DSA:3.10.350.10 94 147 4.6E-18 T 12-10-2018 IPR036779 LysM domain superfamily HW35_08870 bdba6f676821ab9c222013fb25545498 355 Gene3D G3DSA:3.10.350.10 166 222 3.4E-23 T 12-10-2018 IPR036779 LysM domain superfamily HW35_08870 bdba6f676821ab9c222013fb25545498 355 Gene3D G3DSA:3.10.350.10 23 76 4.2E-20 T 12-10-2018 IPR036779 LysM domain superfamily HW35_08870 bdba6f676821ab9c222013fb25545498 355 SUPERFAMILY SSF54106 170 213 5.1E-13 T 12-10-2018 HW35_08870 bdba6f676821ab9c222013fb25545498 355 Pfam PF00877 NlpC/P60 family 249 351 8.5E-31 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain HW35_08870 bdba6f676821ab9c222013fb25545498 355 SMART SM00257 171 214 3.3E-20 T 12-10-2018 IPR018392 LysM domain HW35_08870 bdba6f676821ab9c222013fb25545498 355 SMART SM00257 98 141 2.0E-17 T 12-10-2018 IPR018392 LysM domain HW35_08870 bdba6f676821ab9c222013fb25545498 355 SMART SM00257 27 70 2.0E-16 T 12-10-2018 IPR018392 LysM domain HW35_07480 009fdbe3c58b33e959d1d4c1ffee0fe1 258 Pfam PF00535 Glycosyl transferase family 2 5 167 2.1E-23 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HW35_07480 009fdbe3c58b33e959d1d4c1ffee0fe1 258 Gene3D G3DSA:3.90.550.10 2 256 6.9E-82 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_07480 009fdbe3c58b33e959d1d4c1ffee0fe1 258 SUPERFAMILY SSF53448 2 226 3.56E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_10835 ce72b0f820f33daf03cec2697c8320a4 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 28.244 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10835 ce72b0f820f33daf03cec2697c8320a4 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 3.1E-55 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10835 ce72b0f820f33daf03cec2697c8320a4 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 12-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10835 ce72b0f820f33daf03cec2697c8320a4 121 PIRSF PIRSF002134 1 121 1.3E-44 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10835 ce72b0f820f33daf03cec2697c8320a4 121 SUPERFAMILY SSF46946 2 114 3.68E-47 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 HW35_10835 ce72b0f820f33daf03cec2697c8320a4 121 Gene3D G3DSA:4.10.910.10 72 121 4.2E-27 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10835 ce72b0f820f33daf03cec2697c8320a4 121 Gene3D G3DSA:1.10.8.50 1 71 1.0E-30 T 12-10-2018 HW35_10835 ce72b0f820f33daf03cec2697c8320a4 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 8.5E-36 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 12 635 2.2E-262 T 12-10-2018 IPR011927 Stage V sporulation protein D HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 SUPERFAMILY SSF56601 170 568 5.46E-99 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 201 1.8E-24 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 556 3.1E-87 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 SMART SM00740 579 637 2.2E-14 T 12-10-2018 IPR005543 PASTA domain HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 Gene3D G3DSA:3.30.10.20 582 635 1.9E-8 T 12-10-2018 HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 SUPERFAMILY SSF56519 51 219 1.57E-44 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 Gene3D G3DSA:3.40.710.10 282 477 2.7E-113 T 12-10-2018 HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 Gene3D G3DSA:3.30.450.330 221 559 2.7E-113 T 12-10-2018 HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 Gene3D G3DSA:3.90.1310.30 49 219 1.0E-46 T 12-10-2018 HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 SUPERFAMILY SSF54184 583 636 1.57E-11 T 12-10-2018 HW35_16300 02be4ff47b7833440f083452a10f1ebc 639 Pfam PF03793 PASTA domain 584 636 5.6E-12 T 12-10-2018 IPR005543 PASTA domain HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 Pfam PF01642 Methylmalonyl-CoA mutase 561 1080 1.7E-143 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 Gene3D G3DSA:3.40.50.280 8 149 8.1E-61 T 12-10-2018 HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 Pfam PF03308 ArgK protein 169 413 1.9E-43 T 12-10-2018 HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 Pfam PF02310 B12 binding domain 14 111 5.9E-12 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 Gene3D G3DSA:3.20.20.240 486 1086 1.2E-188 T 12-10-2018 HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 Gene3D G3DSA:3.40.50.300 202 410 6.1E-60 T 12-10-2018 HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 SUPERFAMILY SSF52242 7 145 3.4E-42 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 562 1085 1.2E-115 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 12 1086 17.197 T 12-10-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 SUPERFAMILY SSF52540 153 467 3.27E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 SUPERFAMILY SSF51703 505 1082 6.54E-153 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_09260 90e11afa87581c948fe276dc230a8be0 1086 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 12 125 1.0E-16 T 12-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_11555 070a704bc932529dbb1be37efd20acfa 640 SUPERFAMILY SSF52540 315 530 1.0E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_11555 070a704bc932529dbb1be37efd20acfa 640 SUPERFAMILY SSF52540 4 246 5.41E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_11555 070a704bc932529dbb1be37efd20acfa 640 Gene3D G3DSA:3.40.50.300 290 555 1.4E-62 T 12-10-2018 HW35_11555 070a704bc932529dbb1be37efd20acfa 640 Gene3D G3DSA:3.40.50.300 2 287 6.1E-71 T 12-10-2018 HW35_11555 070a704bc932529dbb1be37efd20acfa 640 Gene3D G3DSA:1.10.287.380 562 640 6.0E-8 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 HW35_11555 070a704bc932529dbb1be37efd20acfa 640 ProSitePatterns PS00211 ABC transporters family signature. 446 460 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_11555 070a704bc932529dbb1be37efd20acfa 640 Pfam PF00005 ABC transporter 345 474 8.7E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_11555 070a704bc932529dbb1be37efd20acfa 640 Pfam PF12848 ABC transporter 232 318 3.4E-25 T 12-10-2018 IPR032781 ABC-transporter extension domain HW35_11555 070a704bc932529dbb1be37efd20acfa 640 SMART SM00382 28 245 3.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_11555 070a704bc932529dbb1be37efd20acfa 640 SMART SM00382 353 518 1.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_11555 070a704bc932529dbb1be37efd20acfa 640 Pfam PF00005 ABC transporter 19 193 2.6E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_11555 070a704bc932529dbb1be37efd20acfa 640 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_11555 070a704bc932529dbb1be37efd20acfa 640 Pfam PF16326 ABC transporter C-terminal domain 572 640 1.1E-13 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 Pfam PF00308 Bacterial dnaA protein 112 328 2.9E-107 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 357 425 1.1E-30 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 Gene3D G3DSA:1.10.8.60 278 346 3.3E-30 T 12-10-2018 HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 447 35.159 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 Pfam PF11638 DnaA N-terminal domain 6 66 1.8E-17 T 12-10-2018 IPR024633 DnaA N-terminal domain HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 SUPERFAMILY SSF48295 343 447 3.14E-37 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 446 4.8E-188 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 Gene3D G3DSA:1.10.1750.10 347 447 1.6E-35 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 Gene3D G3DSA:3.40.50.300 96 276 3.7E-55 T 12-10-2018 HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 Gene3D G3DSA:3.30.300.180 1 82 6.3E-31 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 ProSitePatterns PS01008 DnaA protein signature. 406 425 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 209 223 7.9E-54 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 243 270 7.9E-54 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 177 191 7.9E-54 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 145 165 7.9E-54 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 406 425 7.9E-54 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 SMART SM00382 144 272 2.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 SUPERFAMILY SSF52540 113 324 1.35E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09970 2e2077b7bee2c39685f6de8bc310832e 448 SMART SM00760 356 425 2.0E-41 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 HW35_04280 f934179c9432cc6118209ab1273effa2 410 Gene3D G3DSA:3.40.50.2000 25 397 8.9E-84 T 12-10-2018 HW35_04280 f934179c9432cc6118209ab1273effa2 410 Pfam PF13439 Glycosyltransferase Family 4 35 206 4.4E-29 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 HW35_04280 f934179c9432cc6118209ab1273effa2 410 Gene3D G3DSA:3.40.50.2000 205 381 8.9E-84 T 12-10-2018 HW35_04280 f934179c9432cc6118209ab1273effa2 410 Pfam PF00534 Glycosyl transferases group 1 220 377 7.2E-35 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 HW35_04280 f934179c9432cc6118209ab1273effa2 410 SUPERFAMILY SSF53756 22 400 2.39E-84 T 12-10-2018 HW35_05570 a73b83ae4524e439c6e45327206a8634 167 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 3 165 1.9E-74 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HW35_05570 a73b83ae4524e439c6e45327206a8634 167 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 79 164 1.4E-37 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 HW35_05570 a73b83ae4524e439c6e45327206a8634 167 Gene3D G3DSA:3.30.110.10 72 167 7.6E-37 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 HW35_05570 a73b83ae4524e439c6e45327206a8634 167 SUPERFAMILY SSF55200 78 167 2.09E-33 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 HW35_05570 a73b83ae4524e439c6e45327206a8634 167 SUPERFAMILY SSF54364 2 74 1.57E-29 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HW35_05570 a73b83ae4524e439c6e45327206a8634 167 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 3 72 9.5E-32 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HW35_05570 a73b83ae4524e439c6e45327206a8634 167 ProSitePatterns PS00938 Initiation factor 3 signature. 54 67 - T 12-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 HW35_05570 a73b83ae4524e439c6e45327206a8634 167 Gene3D G3DSA:3.10.20.80 1 71 2.7E-33 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HW35_05570 a73b83ae4524e439c6e45327206a8634 167 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 166 29.421 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 SUPERFAMILY SSF48179 197 289 7.82E-27 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 SMART SM00984 309 405 4.0E-36 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 3 401 6.4E-135 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 178 1.0E-52 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 SUPERFAMILY SSF52413 302 414 3.92E-30 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 PIRSF PIRSF500136 1 420 3.0E-154 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 Gene3D G3DSA:3.40.50.720 1 195 1.8E-69 T 12-10-2018 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 309 403 2.8E-27 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 PIRSF PIRSF000124 2 420 1.0E-82 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 284 1.7E-24 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 Gene3D G3DSA:3.40.50.720 196 424 4.3E-72 T 12-10-2018 HW35_08010 ae782cba3c748f3e6b2a5beb5fcda560 424 SUPERFAMILY SSF51735 3 191 5.04E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 PRINTS PR00956 Flagellar motor switch protein FliN signature 327 340 1.2E-26 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 PRINTS PR00956 Flagellar motor switch protein FliN signature 294 310 1.2E-26 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 PRINTS PR00956 Flagellar motor switch protein FliN signature 340 355 1.2E-26 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 PRINTS PR00956 Flagellar motor switch protein FliN signature 311 327 1.2E-26 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 Gene3D G3DSA:2.30.330.10 285 375 5.5E-35 T 12-10-2018 IPR036429 SpoA-like superfamily HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 Pfam PF04509 CheC-like family 130 165 2.8E-15 T 12-10-2018 IPR007597 CheC-like protein GO:0016787 HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 Pfam PF04509 CheC-like family 34 69 8.3E-11 T 12-10-2018 IPR007597 CheC-like protein GO:0016787 HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 291 365 1.5E-31 T 12-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 SUPERFAMILY SSF103039 28 216 3.49E-48 T 12-10-2018 IPR028976 CheC-like superfamily HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 294 364 9.2E-27 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 Gene3D G3DSA:3.40.1550.10 28 223 2.2E-53 T 12-10-2018 IPR028976 CheC-like superfamily HW35_00235 99e26ffb05fe6d694f9026fbbfa5555b 375 SUPERFAMILY SSF101801 292 371 3.01E-25 T 12-10-2018 IPR036429 SpoA-like superfamily HW35_17045 e4cfd1ecf8fd8d7eea910ca3764e1206 262 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_17045 e4cfd1ecf8fd8d7eea910ca3764e1206 262 Gene3D G3DSA:3.40.50.300 1 250 2.6E-64 T 12-10-2018 HW35_17045 e4cfd1ecf8fd8d7eea910ca3764e1206 262 Pfam PF00005 ABC transporter 18 170 1.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_17045 e4cfd1ecf8fd8d7eea910ca3764e1206 262 SMART SM00382 27 219 5.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_17045 e4cfd1ecf8fd8d7eea910ca3764e1206 262 SUPERFAMILY SSF52540 2 234 3.75E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02600 4ead7f170d97ef9c4877a6fbc7dbc411 277 PIRSF PIRSF006493 1 277 1.4E-109 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type HW35_02600 4ead7f170d97ef9c4877a6fbc7dbc411 277 SMART SM00559 52 181 6.2E-51 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 HW35_02600 4ead7f170d97ef9c4877a6fbc7dbc411 277 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 191 6.2E-43 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 HW35_02600 4ead7f170d97ef9c4877a6fbc7dbc411 277 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 254 34.239 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type HW35_02600 4ead7f170d97ef9c4877a6fbc7dbc411 277 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 256 9.6E-98 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type HW35_02600 4ead7f170d97ef9c4877a6fbc7dbc411 277 SUPERFAMILY SSF100939 2 259 4.12E-57 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily HW35_02600 4ead7f170d97ef9c4877a6fbc7dbc411 277 Gene3D G3DSA:2.40.290.10 2 175 1.2E-21 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily HW35_17490 0f490f4ae768851b8c417b528a1c2650 382 Pfam PF14306 PUA-like domain 6 155 8.9E-47 T 12-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HW35_17490 0f490f4ae768851b8c417b528a1c2650 382 Gene3D G3DSA:3.10.400.10 5 155 5.8E-42 T 12-10-2018 HW35_17490 0f490f4ae768851b8c417b528a1c2650 382 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 22 378 49.926 T 12-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 HW35_17490 0f490f4ae768851b8c417b528a1c2650 382 Gene3D G3DSA:3.40.50.620 164 376 6.3E-98 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_17490 0f490f4ae768851b8c417b528a1c2650 382 SUPERFAMILY SSF52374 164 374 4.07E-87 T 12-10-2018 HW35_17490 0f490f4ae768851b8c417b528a1c2650 382 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 7 374 1.1E-134 T 12-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HW35_17490 0f490f4ae768851b8c417b528a1c2650 382 SUPERFAMILY SSF88697 6 157 7.56E-44 T 12-10-2018 IPR015947 PUA-like superfamily HW35_17490 0f490f4ae768851b8c417b528a1c2650 382 Pfam PF01747 ATP-sulfurylase 164 374 1.1E-95 T 12-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HW35_16330 d3813424d386c8432f0160a5388a126f 367 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 362 35.158 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16330 d3813424d386c8432f0160a5388a126f 367 Gene3D G3DSA:3.40.50.2000 1 176 1.8E-64 T 12-10-2018 HW35_16330 d3813424d386c8432f0160a5388a126f 367 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 353 3.6E-43 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 HW35_16330 d3813424d386c8432f0160a5388a126f 367 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 3.4E-49 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16330 d3813424d386c8432f0160a5388a126f 367 Gene3D G3DSA:3.40.50.2000 177 345 2.1E-49 T 12-10-2018 HW35_16330 d3813424d386c8432f0160a5388a126f 367 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 357 3.5E-104 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16330 d3813424d386c8432f0160a5388a126f 367 SUPERFAMILY SSF53756 1 363 2.02E-111 T 12-10-2018 HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 Gene3D G3DSA:3.60.20.10 21 532 0.0 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 Gene3D G3DSA:3.20.20.70 470 1163 0.0 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 SUPERFAMILY SSF51395 447 1167 7.33E-163 T 12-10-2018 HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 Pfam PF04898 Glutamate synthase central domain 446 725 2.9E-71 T 12-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 Gene3D G3DSA:3.20.20.70 421 772 0.0 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 Gene3D G3DSA:2.160.20.60 1198 1489 5.3E-60 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 Pfam PF01493 GXGXG motif 1369 1408 1.3E-6 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 Pfam PF01493 GXGXG motif 1248 1349 4.9E-12 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 SUPERFAMILY SSF69336 1215 1486 2.35E-44 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 Pfam PF01645 Conserved region in glutamate synthase 787 1147 5.5E-104 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 SUPERFAMILY SSF56235 21 408 3.43E-73 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HW35_14280 3aa47c2eeca6ba10aa89858c697ccd23 1489 Pfam PF00310 Glutamine amidotransferases class-II 21 386 5.9E-48 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain HW35_06740 864ca4516eaa70a7eddd75f5fcbc20aa 71 Pfam PF13217 Protein of unknown function (DUF4025) 7 51 2.3E-13 T 12-10-2018 IPR025100 Protein of unknown function DUF4025 HW35_03775 3c8c84c81e96cdf20aa0fb6682e9bccf 306 Pfam PF12146 Serine aminopeptidase, S33 81 193 4.9E-11 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 HW35_03775 3c8c84c81e96cdf20aa0fb6682e9bccf 306 Gene3D G3DSA:3.40.50.1820 58 303 2.3E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_03775 3c8c84c81e96cdf20aa0fb6682e9bccf 306 SUPERFAMILY SSF53474 47 299 4.13E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_08705 d296d988f30b3a30ffb00b3af132955c 318 Pfam PF01238 Phosphomannose isomerase type I 7 316 3.2E-45 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 HW35_08705 d296d988f30b3a30ffb00b3af132955c 318 SUPERFAMILY SSF51182 4 317 1.24E-105 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily HW35_08705 d296d988f30b3a30ffb00b3af132955c 318 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 114 316 2.6E-44 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 HW35_08705 d296d988f30b3a30ffb00b3af132955c 318 Gene3D G3DSA:2.60.120.10 1 228 1.4E-95 T 12-10-2018 IPR014710 RmlC-like jelly roll fold HW35_08705 d296d988f30b3a30ffb00b3af132955c 318 Gene3D G3DSA:2.60.120.10 231 317 7.9E-27 T 12-10-2018 IPR014710 RmlC-like jelly roll fold HW35_08705 d296d988f30b3a30ffb00b3af132955c 318 PIRSF PIRSF036894 3 318 4.4E-133 T 12-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 HW35_09635 8965de41e12ade3e6e496c9fa00bca63 513 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 451 1.2E-35 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 HW35_09635 8965de41e12ade3e6e496c9fa00bca63 513 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 4 507 2.8E-282 T 12-10-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 HW35_09635 8965de41e12ade3e6e496c9fa00bca63 513 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HW35_09635 8965de41e12ade3e6e496c9fa00bca63 513 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 131 143 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HW35_09635 8965de41e12ade3e6e496c9fa00bca63 513 Gene3D G3DSA:3.30.420.40 248 512 2.9E-87 T 12-10-2018 HW35_09635 8965de41e12ade3e6e496c9fa00bca63 513 SUPERFAMILY SSF53067 4 248 2.88E-66 T 12-10-2018 HW35_09635 8965de41e12ade3e6e496c9fa00bca63 513 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 246 1.1E-81 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 HW35_09635 8965de41e12ade3e6e496c9fa00bca63 513 PIRSF PIRSF000538 2 503 1.4E-136 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HW35_09635 8965de41e12ade3e6e496c9fa00bca63 513 Gene3D G3DSA:3.30.420.40 1 247 2.8E-79 T 12-10-2018 HW35_09635 8965de41e12ade3e6e496c9fa00bca63 513 SUPERFAMILY SSF53067 249 498 1.57E-65 T 12-10-2018 HW35_13345 ce8fd68d9d05db60eb3405ac85603c42 240 Gene3D G3DSA:3.40.50.300 1 240 4.5E-81 T 12-10-2018 HW35_13345 ce8fd68d9d05db60eb3405ac85603c42 240 PIRSF PIRSF039085 1 240 4.5E-121 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HW35_13345 ce8fd68d9d05db60eb3405ac85603c42 240 Pfam PF00005 ABC transporter 17 165 1.2E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_13345 ce8fd68d9d05db60eb3405ac85603c42 240 SUPERFAMILY SSF52540 1 235 1.27E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13345 ce8fd68d9d05db60eb3405ac85603c42 240 SMART SM00382 26 221 7.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_13345 ce8fd68d9d05db60eb3405ac85603c42 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_06175 56cae87b5108a488279420d61e6782c4 265 SUPERFAMILY SSF53474 15 262 2.03E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_06175 56cae87b5108a488279420d61e6782c4 265 Pfam PF00326 Prolyl oligopeptidase family 70 263 2.0E-18 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 HW35_06175 56cae87b5108a488279420d61e6782c4 265 Gene3D G3DSA:3.40.50.1820 26 265 1.8E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_11980 5cf5afab141155f55418f715ae4cfbfd 163 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 13 134 2.3E-42 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 HW35_11980 5cf5afab141155f55418f715ae4cfbfd 163 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 12 136 2.9E-49 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 HW35_11980 5cf5afab141155f55418f715ae4cfbfd 163 Gene3D G3DSA:2.70.70.10 3 162 1.7E-54 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_11980 5cf5afab141155f55418f715ae4cfbfd 163 SUPERFAMILY SSF51261 3 159 6.98E-52 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_11980 5cf5afab141155f55418f715ae4cfbfd 163 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 76 88 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 HW35_12245 c5266ec84a5129a399b8ff730903c436 167 Gene3D G3DSA:1.20.120.450 1 150 1.2E-37 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes HW35_12245 c5266ec84a5129a399b8ff730903c436 167 SUPERFAMILY SSF109854 7 152 1.07E-30 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes HW35_12245 c5266ec84a5129a399b8ff730903c436 167 Pfam PF05163 DinB family 3 157 5.9E-31 T 12-10-2018 IPR007837 DNA damage-inducible protein DinB HW35_11425 01b60f59bf2cd7ad969e952d190fffdd 93 Gene3D G3DSA:1.10.1220.10 1 93 2.0E-42 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 HW35_11985 bec6538b04bcf0e6ec84308a230e3b42 480 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 474 3.4E-202 T 12-10-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 HW35_11985 bec6538b04bcf0e6ec84308a230e3b42 480 Pfam PF02378 Phosphotransferase system, EIIC 10 315 1.1E-75 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HW35_11985 bec6538b04bcf0e6ec84308a230e3b42 480 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 417 434 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HW35_11985 bec6538b04bcf0e6ec84308a230e3b42 480 Gene3D G3DSA:3.30.1360.60 401 480 4.8E-24 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 HW35_11985 bec6538b04bcf0e6ec84308a230e3b42 480 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 374 464 7.4E-22 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HW35_11985 bec6538b04bcf0e6ec84308a230e3b42 480 SUPERFAMILY SSF55604 404 477 5.62E-21 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 HW35_11985 bec6538b04bcf0e6ec84308a230e3b42 480 Pfam PF00367 phosphotransferase system, EIIB 407 439 1.9E-14 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HW35_07500 ad352b2d5736037f90be2b0fab7277a9 186 SUPERFAMILY SSF51182 1 184 1.25E-78 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily HW35_07500 ad352b2d5736037f90be2b0fab7277a9 186 Gene3D G3DSA:2.60.120.10 3 183 3.8E-76 T 12-10-2018 IPR014710 RmlC-like jelly roll fold HW35_07500 ad352b2d5736037f90be2b0fab7277a9 186 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 175 1.6E-75 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HW35_07500 ad352b2d5736037f90be2b0fab7277a9 186 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 177 1.9E-77 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HW35_07500 ad352b2d5736037f90be2b0fab7277a9 186 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 179 2.0E-65 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 3 804 0.0 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 804 23.558 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 Pfam PF09334 tRNA synthetases class I (M) 39 170 1.2E-17 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 Gene3D G3DSA:3.40.50.620 32 571 1.7E-282 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 Gene3D G3DSA:1.10.730.10 599 741 1.8E-47 T 12-10-2018 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 Gene3D G3DSA:3.10.20.590 745 804 1.9E-20 T 12-10-2018 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 SUPERFAMILY SSF50677 224 410 4.29E-57 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 9.2E-70 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 SUPERFAMILY SSF47323 618 804 2.8E-40 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 603 5.5E-20 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 Gene3D G3DSA:2.30.210.10 572 587 1.7E-282 T 12-10-2018 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 Pfam PF08264 Anticodon-binding domain of tRNA 656 768 1.0E-21 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 Gene3D G3DSA:3.90.740.10 226 410 1.7E-282 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 SUPERFAMILY SSF52374 1 625 2.02E-149 T 12-10-2018 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 3.4E-58 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 3.4E-58 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 3.4E-58 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 3.4E-58 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 3.4E-58 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 3.4E-58 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HW35_06115 43602ba0aa543e2f7bd6d5cd74e8c3c5 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 3.4E-58 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HW35_05475 15dd7130041a4e3f03232b145a175da1 568 Pfam PF00501 AMP-binding enzyme 32 462 1.4E-115 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_05475 15dd7130041a4e3f03232b145a175da1 568 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 546 4.8E-20 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_05475 15dd7130041a4e3f03232b145a175da1 568 ProSitePatterns PS00455 Putative AMP-binding domain signature. 213 224 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_05475 15dd7130041a4e3f03232b145a175da1 568 Gene3D G3DSA:3.40.50.12780 9 453 1.7E-129 T 12-10-2018 HW35_05475 15dd7130041a4e3f03232b145a175da1 568 Gene3D G3DSA:3.30.300.310 458 562 8.2E-33 T 12-10-2018 HW35_05475 15dd7130041a4e3f03232b145a175da1 568 SUPERFAMILY SSF56801 21 557 7.33E-158 T 12-10-2018 HW35_10760 a251b70235305e4188dae0ad5d88b289 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 2.0E-33 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10760 a251b70235305e4188dae0ad5d88b289 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10760 a251b70235305e4188dae0ad5d88b289 87 SUPERFAMILY SSF50249 7 84 2.23E-33 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_10760 a251b70235305e4188dae0ad5d88b289 87 Pfam PF00366 Ribosomal protein S17 12 79 5.9E-34 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10760 a251b70235305e4188dae0ad5d88b289 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 25.036 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10760 a251b70235305e4188dae0ad5d88b289 87 Gene3D G3DSA:2.40.50.140 6 86 2.4E-37 T 12-10-2018 HW35_10760 a251b70235305e4188dae0ad5d88b289 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 8.7E-13 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10760 a251b70235305e4188dae0ad5d88b289 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 8.7E-13 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10760 a251b70235305e4188dae0ad5d88b289 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 8.7E-13 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10760 a251b70235305e4188dae0ad5d88b289 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 5.9E-37 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 Gene3D G3DSA:2.30.30.100 276 327 2.5E-8 T 12-10-2018 HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 SUPERFAMILY SSF46785 3 61 5.45E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 Pfam PF08279 HTH domain 12 60 2.7E-13 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 Gene3D G3DSA:1.10.10.10 2 65 1.8E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 Gene3D G3DSA:3.30.930.10 72 275 3.3E-63 T 12-10-2018 HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 SUPERFAMILY SSF55681 72 276 3.73E-59 T 12-10-2018 HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 326 37.226 T 12-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 SUPERFAMILY SSF50037 284 326 2.06E-5 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 Pfam PF02237 Biotin protein ligase C terminal domain 280 326 3.1E-11 T 12-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 86 326 3.9E-68 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_03225 1f42ecf167b65befbbd96436ab7aa626 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 90 214 6.4E-17 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 SUPERFAMILY SSF56014 147 345 6.54E-59 T 12-10-2018 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 SUPERFAMILY SSF55124 13 146 1.16E-32 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 354 419 5.2E-14 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 76 136 5.9E-15 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 Gene3D G3DSA:3.30.413.10 428 569 1.3E-38 T 12-10-2018 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 9 572 58.934 T 12-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 18 561 8.6E-280 T 12-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 431 562 0.01 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 480 496 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 PRINTS PR00397 Sirohaem Fe-binding site signature 432 450 1.6E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 PRINTS PR00397 Sirohaem Fe-binding site signature 480 498 1.6E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 SUPERFAMILY SSF55124 347 422 3.76E-22 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 171 331 3.4E-50 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HW35_01215 b08eb8cbabeaf39282fedf4ef5b3b52e 572 SUPERFAMILY SSF56014 430 562 5.63E-36 T 12-10-2018 HW35_13425 25476fd773bd008a3e7c61ea39e2a3e0 592 SUPERFAMILY SSF55781 242 367 2.23E-6 T 12-10-2018 HW35_13425 25476fd773bd008a3e7c61ea39e2a3e0 592 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 476 575 7.7E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_13425 25476fd773bd008a3e7c61ea39e2a3e0 592 Pfam PF07694 5TMR of 5TMR-LYT 26 207 7.5E-57 T 12-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 HW35_13425 25476fd773bd008a3e7c61ea39e2a3e0 592 SUPERFAMILY SSF55874 432 575 1.44E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_13425 25476fd773bd008a3e7c61ea39e2a3e0 592 Gene3D G3DSA:3.30.565.10 438 584 1.6E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_13425 25476fd773bd008a3e7c61ea39e2a3e0 592 Pfam PF13492 GAF domain 274 363 1.2E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 HW35_13425 25476fd773bd008a3e7c61ea39e2a3e0 592 Pfam PF06580 Histidine kinase 377 455 9.6E-25 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 HW35_13425 25476fd773bd008a3e7c61ea39e2a3e0 592 SMART SM00387 469 578 0.0049 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_06915 5e6058220d885a29c4a0ba6b0e7fee0a 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.0E-7 T 12-10-2018 HW35_06915 5e6058220d885a29c4a0ba6b0e7fee0a 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 2.0E-7 T 12-10-2018 HW35_06915 5e6058220d885a29c4a0ba6b0e7fee0a 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 2.0E-7 T 12-10-2018 HW35_06915 5e6058220d885a29c4a0ba6b0e7fee0a 405 Gene3D G3DSA:3.50.50.100 1 405 1.9E-144 T 12-10-2018 HW35_06915 5e6058220d885a29c4a0ba6b0e7fee0a 405 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 325 1.5E-48 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_06915 5e6058220d885a29c4a0ba6b0e7fee0a 405 SUPERFAMILY SSF51905 5 339 8.64E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_12545 57e715176fdac902b3c5f88253e1be39 487 SUPERFAMILY SSF53720 4 485 3.27E-157 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HW35_12545 57e715176fdac902b3c5f88253e1be39 487 Gene3D G3DSA:3.40.309.10 254 454 2.7E-160 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 HW35_12545 57e715176fdac902b3c5f88253e1be39 487 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 10 485 2.8E-180 T 12-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 HW35_12545 57e715176fdac902b3c5f88253e1be39 487 Pfam PF00171 Aldehyde dehydrogenase family 17 479 4.2E-155 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 HW35_12545 57e715176fdac902b3c5f88253e1be39 487 Gene3D G3DSA:3.40.605.10 25 462 2.7E-160 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_12545 57e715176fdac902b3c5f88253e1be39 487 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 HW35_12545 57e715176fdac902b3c5f88253e1be39 487 Hamap MF_01670 Malonate-semialdehyde dehydrogenase [iolA]. 3 485 72.742 T 12-10-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642 HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 Pfam PF12836 Helix-hairpin-helix motif 488 552 4.7E-27 T 12-10-2018 HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 Gene3D G3DSA:3.30.420.140 322 448 1.6E-160 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 Gene3D G3DSA:1.10.150.310 496 630 4.9E-46 T 12-10-2018 HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 SUPERFAMILY SSF53098 319 466 4.32E-50 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 Gene3D G3DSA:1.10.10.650 6 115 1.6E-40 T 12-10-2018 IPR023319 Tex-like protein, HTH domain superfamily HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 SMART SM00732 323 421 1.5E-33 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 SMART SM00316 649 720 3.9E-23 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 SUPERFAMILY SSF158832 10 318 6.54E-121 T 12-10-2018 HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 SUPERFAMILY SSF47781 558 632 3.11E-15 T 12-10-2018 IPR010994 RuvA domain 2-like HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 SUPERFAMILY SSF50249 635 721 5.3E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 Pfam PF16921 Tex protein YqgF-like domain 323 448 4.7E-57 T 12-10-2018 IPR032639 Tex protein, YqgF-like domain HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 Pfam PF00575 S1 RNA binding domain 649 719 8.7E-17 T 12-10-2018 IPR003029 S1 domain GO:0003676 HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 Pfam PF09371 Tex-like protein N-terminal domain 16 198 3.7E-73 T 12-10-2018 IPR018974 Tex-like protein, N-terminal HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 SUPERFAMILY SSF47781 467 553 8.12E-27 T 12-10-2018 IPR010994 RuvA domain 2-like HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 Gene3D G3DSA:2.40.50.140 635 721 6.7E-25 T 12-10-2018 HW35_11445 a6ce177f9c95a2448ceb92f10f2e59f6 723 Gene3D G3DSA:1.10.3500.10 118 495 1.6E-160 T 12-10-2018 IPR023323 Tex-like domain superfamily HW35_09115 7218f90a9509b5111ce8e5db81aa4437 236 Hamap MF_01393 ATP synthase subunit a [atpB]. 13 235 13.479 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09115 7218f90a9509b5111ce8e5db81aa4437 236 ProSitePatterns PS00449 ATP synthase a subunit signature. 165 174 - T 12-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09115 7218f90a9509b5111ce8e5db81aa4437 236 Gene3D G3DSA:1.20.120.220 71 236 3.7E-41 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09115 7218f90a9509b5111ce8e5db81aa4437 236 SUPERFAMILY SSF81336 70 229 9.02E-41 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09115 7218f90a9509b5111ce8e5db81aa4437 236 PRINTS PR00123 ATP synthase A subunit signature 162 184 6.6E-17 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09115 7218f90a9509b5111ce8e5db81aa4437 236 PRINTS PR00123 ATP synthase A subunit signature 215 230 6.6E-17 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09115 7218f90a9509b5111ce8e5db81aa4437 236 PRINTS PR00123 ATP synthase A subunit signature 78 94 6.6E-17 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09115 7218f90a9509b5111ce8e5db81aa4437 236 Pfam PF00119 ATP synthase A chain 20 229 1.3E-58 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09115 7218f90a9509b5111ce8e5db81aa4437 236 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 15 231 1.9E-48 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_16130 7b866a3cf8d95ebe5b873b15fffc6f24 144 SMART SM00116 11 58 7.3E-9 T 12-10-2018 IPR000644 CBS domain HW35_16130 7b866a3cf8d95ebe5b873b15fffc6f24 144 SMART SM00116 75 122 3.8E-15 T 12-10-2018 IPR000644 CBS domain HW35_16130 7b866a3cf8d95ebe5b873b15fffc6f24 144 SUPERFAMILY SSF54631 3 117 9.22E-35 T 12-10-2018 HW35_16130 7b866a3cf8d95ebe5b873b15fffc6f24 144 Pfam PF00571 CBS domain 68 117 1.4E-16 T 12-10-2018 IPR000644 CBS domain HW35_16130 7b866a3cf8d95ebe5b873b15fffc6f24 144 Pfam PF00571 CBS domain 6 54 3.1E-10 T 12-10-2018 IPR000644 CBS domain HW35_16130 7b866a3cf8d95ebe5b873b15fffc6f24 144 Gene3D G3DSA:3.10.580.10 1 144 2.0E-41 T 12-10-2018 HW35_01165 a775f7131c515cde01107d929b83ef7f 472 SUPERFAMILY SSF51338 1 455 1.96E-37 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_01165 a775f7131c515cde01107d929b83ef7f 472 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 4 455 1.8E-205 T 12-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 HW35_01165 a775f7131c515cde01107d929b83ef7f 472 Gene3D G3DSA:3.20.20.140 53 424 3.7E-191 T 12-10-2018 HW35_01165 a775f7131c515cde01107d929b83ef7f 472 SUPERFAMILY SSF51556 53 383 3.27E-111 T 12-10-2018 IPR032466 Metal-dependent hydrolase HW35_01165 a775f7131c515cde01107d929b83ef7f 472 Gene3D G3DSA:2.30.40.10 4 456 3.7E-191 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_01165 a775f7131c515cde01107d929b83ef7f 472 Pfam PF01979 Amidohydrolase family 49 437 4.0E-28 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 HW35_02905 0faeb2c4087e598ada83a9c3027932dc 629 Pfam PF00005 ABC transporter 20 187 1.4E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_02905 0faeb2c4087e598ada83a9c3027932dc 629 SUPERFAMILY SSF52540 4 238 4.28E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02905 0faeb2c4087e598ada83a9c3027932dc 629 SUPERFAMILY SSF52540 316 530 1.0E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02905 0faeb2c4087e598ada83a9c3027932dc 629 Pfam PF16326 ABC transporter C-terminal domain 558 624 1.2E-12 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 HW35_02905 0faeb2c4087e598ada83a9c3027932dc 629 Gene3D G3DSA:3.40.50.300 282 560 9.2E-61 T 12-10-2018 HW35_02905 0faeb2c4087e598ada83a9c3027932dc 629 SMART SM00382 345 515 2.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_02905 0faeb2c4087e598ada83a9c3027932dc 629 SMART SM00382 28 231 4.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_02905 0faeb2c4087e598ada83a9c3027932dc 629 Pfam PF12848 ABC transporter 226 295 8.0E-15 T 12-10-2018 IPR032781 ABC-transporter extension domain HW35_02905 0faeb2c4087e598ada83a9c3027932dc 629 Pfam PF00005 ABC transporter 336 471 1.4E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_02905 0faeb2c4087e598ada83a9c3027932dc 629 Gene3D G3DSA:3.40.50.300 1 281 3.4E-69 T 12-10-2018 HW35_06040 4164d6752c86b3a920711c3f87428110 284 ProSitePatterns PS00770 Aminotransferases class-IV signature. 178 207 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 HW35_06040 4164d6752c86b3a920711c3f87428110 284 Gene3D G3DSA:3.30.470.10 1 118 3.2E-38 T 12-10-2018 HW35_06040 4164d6752c86b3a920711c3f87428110 284 Gene3D G3DSA:3.20.10.10 121 282 2.4E-57 T 12-10-2018 HW35_06040 4164d6752c86b3a920711c3f87428110 284 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 5 278 2.8E-126 T 12-10-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 HW35_06040 4164d6752c86b3a920711c3f87428110 284 Pfam PF01063 Amino-transferase class IV 30 251 2.8E-51 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 HW35_06040 4164d6752c86b3a920711c3f87428110 284 SUPERFAMILY SSF56752 5 275 7.72E-83 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 HW35_01800 7fca1b3e77b9f80015fb9592a0f8803d 202 SMART SM01007 8 187 6.0E-57 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal HW35_01800 7fca1b3e77b9f80015fb9592a0f8803d 202 SUPERFAMILY SSF53639 4 194 1.26E-54 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily HW35_01800 7fca1b3e77b9f80015fb9592a0f8803d 202 Gene3D G3DSA:3.40.225.10 1 202 1.5E-62 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily HW35_01800 7fca1b3e77b9f80015fb9592a0f8803d 202 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 185 6.6E-48 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal HW35_10190 5fac8dcc172204bb9dc297a6e3168028 94 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 3.4E-11 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HW35_10190 5fac8dcc172204bb9dc297a6e3168028 94 SUPERFAMILY SSF89447 1 52 5.36E-17 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily HW35_10190 5fac8dcc172204bb9dc297a6e3168028 94 SMART SM00966 8 51 1.3E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HW35_10190 5fac8dcc172204bb9dc297a6e3168028 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 4.2E-12 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HW35_10190 5fac8dcc172204bb9dc297a6e3168028 94 Gene3D G3DSA:2.10.260.10 1 51 2.1E-26 T 12-10-2018 HW35_10410 88ac171435e427c09258aab29409d514 330 SUPERFAMILY SSF51395 11 322 2.75E-92 T 12-10-2018 HW35_10410 88ac171435e427c09258aab29409d514 330 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 322 5.7E-136 T 12-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 HW35_10410 88ac171435e427c09258aab29409d514 330 Gene3D G3DSA:1.10.1200.80 253 328 2.0E-18 T 12-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 HW35_10410 88ac171435e427c09258aab29409d514 330 Gene3D G3DSA:3.20.20.70 7 249 7.0E-83 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_10410 88ac171435e427c09258aab29409d514 330 Pfam PF01207 Dihydrouridine synthase (Dus) 14 316 1.7E-109 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HW35_10410 88ac171435e427c09258aab29409d514 330 PIRSF PIRSF006621 1 330 1.1E-108 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HW35_10410 88ac171435e427c09258aab29409d514 330 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 Gene3D G3DSA:3.40.50.300 112 309 1.0E-116 T 12-10-2018 HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 SMART SM00963 22 103 5.6E-27 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 SMART SM00382 119 310 4.5E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 4.2E-82 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 SMART SM00962 120 321 6.3E-123 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 SUPERFAMILY SSF52540 121 319 4.46E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 SUPERFAMILY SSF47364 18 96 8.9E-22 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 320 1.1E-117 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 64.913 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 Gene3D G3DSA:1.20.120.140 20 318 1.0E-116 T 12-10-2018 HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_16665 34786e6c6de321572abc5dbe4accee3b 330 Pfam PF02881 SRP54-type protein, helical bundle domain 33 99 5.8E-15 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HW35_09190 3fa34881df2165add4ea0b71b7445a15 357 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.851 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 HW35_09190 3fa34881df2165add4ea0b71b7445a15 357 Gene3D G3DSA:3.30.160.20 209 295 9.4E-97 T 12-10-2018 HW35_09190 3fa34881df2165add4ea0b71b7445a15 357 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 355 1.6E-172 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 HW35_09190 3fa34881df2165add4ea0b71b7445a15 357 SUPERFAMILY SSF75620 8 351 6.41E-135 T 12-10-2018 HW35_09190 3fa34881df2165add4ea0b71b7445a15 357 SMART SM00937 63 177 5.4E-66 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 HW35_09190 3fa34881df2165add4ea0b71b7445a15 357 Gene3D G3DSA:3.30.70.1660 110 340 9.4E-97 T 12-10-2018 HW35_09190 3fa34881df2165add4ea0b71b7445a15 357 Pfam PF00472 RF-1 domain 210 319 5.0E-41 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HW35_09190 3fa34881df2165add4ea0b71b7445a15 357 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HW35_09190 3fa34881df2165add4ea0b71b7445a15 357 Gene3D G3DSA:1.20.58.410 1 100 1.9E-11 T 12-10-2018 HW35_09190 3fa34881df2165add4ea0b71b7445a15 357 Pfam PF03462 PCRF domain 9 202 1.8E-76 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 SUPERFAMILY SSF55874 434 602 3.41E-51 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 SUPERFAMILY SSF55785 253 370 2.39E-14 T 12-10-2018 IPR035965 PAS domain superfamily HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 Pfam PF00512 His Kinase A (phospho-acceptor) domain 379 444 2.0E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 Pfam PF13426 PAS domain 276 371 5.2E-11 T 12-10-2018 IPR000014 PAS domain HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 SUPERFAMILY SSF158472 207 255 6.8E-10 T 12-10-2018 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 Gene3D G3DSA:3.30.565.10 450 608 5.4E-51 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 Gene3D G3DSA:3.30.450.20 273 369 1.2E-23 T 12-10-2018 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 580 5.9E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 599 5.9E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 555 5.9E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 541 5.9E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 SMART SM00388 378 445 1.2E-21 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 SUPERFAMILY SSF47384 365 445 2.35E-20 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 Gene3D G3DSA:1.10.287.130 370 449 2.9E-29 T 12-10-2018 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 Gene3D G3DSA:1.10.8.500 205 257 8.2E-10 T 12-10-2018 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 491 601 6.7E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 SMART SM00387 490 602 3.2E-43 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 Gene3D G3DSA:3.30.450.20 32 184 3.3E-41 T 12-10-2018 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 SMART SM00304 206 258 1.3E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 265 376 1.8E-7 T 12-10-2018 IPR000014 PAS domain HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 SMART SM00091 265 331 4.6E-8 T 12-10-2018 IPR000014 PAS domain HW35_09800 879b7944cc6855e5dc70304b4293a3a1 609 Pfam PF00672 HAMP domain 207 255 2.7E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_10710 f3e2fc9a7404a95af6346546f969ece8 102 Gene3D G3DSA:3.30.70.600 1 102 1.2E-38 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily HW35_10710 f3e2fc9a7404a95af6346546f969ece8 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.243 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10710 f3e2fc9a7404a95af6346546f969ece8 102 SMART SM01403 7 101 8.7E-61 T 12-10-2018 IPR027486 Ribosomal protein S10 domain HW35_10710 f3e2fc9a7404a95af6346546f969ece8 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.3E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10710 f3e2fc9a7404a95af6346546f969ece8 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.3E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10710 f3e2fc9a7404a95af6346546f969ece8 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.3E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10710 f3e2fc9a7404a95af6346546f969ece8 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10710 f3e2fc9a7404a95af6346546f969ece8 102 SUPERFAMILY SSF54999 5 102 9.02E-39 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily HW35_10710 f3e2fc9a7404a95af6346546f969ece8 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.3E-47 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10710 f3e2fc9a7404a95af6346546f969ece8 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.0E-36 T 12-10-2018 IPR027486 Ribosomal protein S10 domain HW35_01245 3c3428fc02e74613dcc274615f8e6df3 64 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 37 51 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HW35_01245 3c3428fc02e74613dcc274615f8e6df3 64 Gene3D G3DSA:1.10.8.910 4 64 2.0E-28 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily HW35_01245 3c3428fc02e74613dcc274615f8e6df3 64 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 4 58 3.2E-21 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 HW35_01245 3c3428fc02e74613dcc274615f8e6df3 64 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 19 28 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Pfam PF00874 PRD domain 322 404 5.9E-16 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Pfam PF00874 PRD domain 212 291 2.3E-14 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Gene3D G3DSA:3.40.930.10 518 667 7.1E-13 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 SUPERFAMILY SSF63520 318 407 6.41E-17 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Pfam PF08279 HTH domain 11 67 5.6E-8 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Gene3D G3DSA:1.10.1790.10 201 295 1.7E-14 T 12-10-2018 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Gene3D G3DSA:3.40.50.2300 413 504 4.1E-11 T 12-10-2018 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 533 664 1.7E-11 T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 SUPERFAMILY SSF46894 3 70 3.97E-6 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Pfam PF05043 Mga helix-turn-helix domain 87 177 2.7E-13 T 12-10-2018 IPR007737 Mga helix-turn-helix domain HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 SUPERFAMILY SSF55804 523 666 1.1E-15 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Gene3D G3DSA:1.10.1790.10 312 406 6.7E-15 T 12-10-2018 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 415 494 3.6E-7 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 SUPERFAMILY SSF52794 413 497 2.14E-10 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 SUPERFAMILY SSF63520 207 291 6.02E-16 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_11180 83df4be7935afa15fe6a45a00e5aff65 672 Gene3D G3DSA:1.10.10.10 2 71 2.5E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_14450 a1707d138d2bda9aa9e81748b561ef4f 375 SUPERFAMILY SSF52540 104 347 2.86E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14450 a1707d138d2bda9aa9e81748b561ef4f 375 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 139 152 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HW35_14450 a1707d138d2bda9aa9e81748b561ef4f 375 Gene3D G3DSA:3.40.50.300 104 358 9.0E-60 T 12-10-2018 HW35_14450 a1707d138d2bda9aa9e81748b561ef4f 375 Pfam PF01580 FtsK/SpoIIIE family 114 279 6.5E-22 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 Gene3D G3DSA:1.10.510.10 92 278 2.7E-57 T 12-10-2018 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 SUPERFAMILY SSF56112 8 267 3.51E-86 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 SUPERFAMILY SSF54184 366 427 8.24E-5 T 12-10-2018 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 SMART SM00740 362 429 5.3E-17 T 12-10-2018 IPR005543 PASTA domain HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 SMART SM00740 498 565 4.2E-14 T 12-10-2018 IPR005543 PASTA domain HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 SMART SM00740 430 497 4.7E-12 T 12-10-2018 IPR005543 PASTA domain HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 Pfam PF03793 PASTA domain 366 428 1.5E-14 T 12-10-2018 IPR005543 PASTA domain HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 Pfam PF03793 PASTA domain 435 497 2.4E-13 T 12-10-2018 IPR005543 PASTA domain HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 Pfam PF03793 PASTA domain 504 565 2.0E-11 T 12-10-2018 IPR005543 PASTA domain HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 Gene3D G3DSA:3.30.10.20 431 500 7.1E-12 T 12-10-2018 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 Gene3D G3DSA:3.30.10.20 360 430 1.4E-17 T 12-10-2018 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 Gene3D G3DSA:3.30.10.20 501 568 1.3E-14 T 12-10-2018 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 Gene3D G3DSA:3.30.200.20 1 90 3.8E-34 T 12-10-2018 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 Gene3D G3DSA:2.60.40.2560 573 653 5.3E-16 T 12-10-2018 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 SMART SM00220 11 268 1.8E-72 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HW35_16575 8e90cbc2ace7d19364ff7774619322c2 657 Pfam PF00069 Protein kinase domain 11 260 3.7E-58 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HW35_12515 5e7197ea41f49c70d8c3e7629e9cb708 502 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_12515 5e7197ea41f49c70d8c3e7629e9cb708 502 Gene3D G3DSA:3.40.50.300 3 234 4.7E-57 T 12-10-2018 HW35_12515 5e7197ea41f49c70d8c3e7629e9cb708 502 SUPERFAMILY SSF52540 7 229 3.86E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12515 5e7197ea41f49c70d8c3e7629e9cb708 502 Gene3D G3DSA:3.40.50.300 266 500 4.0E-43 T 12-10-2018 HW35_12515 5e7197ea41f49c70d8c3e7629e9cb708 502 SMART SM00382 285 482 0.0014 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_12515 5e7197ea41f49c70d8c3e7629e9cb708 502 SMART SM00382 33 225 8.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_12515 5e7197ea41f49c70d8c3e7629e9cb708 502 SUPERFAMILY SSF52540 278 491 5.33E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12515 5e7197ea41f49c70d8c3e7629e9cb708 502 Pfam PF00005 ABC transporter 279 431 4.8E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12515 5e7197ea41f49c70d8c3e7629e9cb708 502 Pfam PF00005 ABC transporter 24 177 4.7E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_13270 c14e6fb7337520746fe912f1675e7987 442 Pfam PF13276 HTH-like domain 195 250 1.3E-12 T 12-10-2018 IPR025948 HTH-like domain HW35_13270 c14e6fb7337520746fe912f1675e7987 442 Pfam PF00665 Integrase core domain 280 395 1.5E-21 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_13270 c14e6fb7337520746fe912f1675e7987 442 Gene3D G3DSA:3.30.420.10 274 439 1.3E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_13270 c14e6fb7337520746fe912f1675e7987 442 SUPERFAMILY SSF53098 272 437 2.28E-28 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_00825 fc0385e6a76bb318a97ed82b8633e590 142 Gene3D G3DSA:3.40.630.30 2 141 1.5E-20 T 12-10-2018 HW35_00825 fc0385e6a76bb318a97ed82b8633e590 142 Pfam PF00583 Acetyltransferase (GNAT) family 35 129 4.3E-10 T 12-10-2018 IPR000182 GNAT domain HW35_00825 fc0385e6a76bb318a97ed82b8633e590 142 SUPERFAMILY SSF55729 8 133 3.21E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_11275 10a3be52a5a8dd45c040b4bea2111008 73 SUPERFAMILY SSF47413 1 68 2.53E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_11275 10a3be52a5a8dd45c040b4bea2111008 73 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 67 4.3E-24 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_11275 10a3be52a5a8dd45c040b4bea2111008 73 SMART SM00530 6 62 4.3E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_11275 10a3be52a5a8dd45c040b4bea2111008 73 Gene3D G3DSA:1.10.260.40 4 68 3.5E-10 T 12-10-2018 HW35_07905 4e5efb53a979fda89045bad69a68433b 388 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 380 3.8E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_07905 4e5efb53a979fda89045bad69a68433b 388 PIRSF PIRSF003169 1 385 1.8E-148 T 12-10-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 HW35_07905 4e5efb53a979fda89045bad69a68433b 388 SUPERFAMILY SSF55874 270 379 2.62E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_07905 4e5efb53a979fda89045bad69a68433b 388 Gene3D G3DSA:3.30.565.10 246 385 3.9E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_07905 4e5efb53a979fda89045bad69a68433b 388 SMART SM00387 288 381 1.5E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_07905 4e5efb53a979fda89045bad69a68433b 388 Pfam PF07730 Histidine kinase 180 248 4.2E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HW35_07905 4e5efb53a979fda89045bad69a68433b 388 Pfam PF05384 Sensor protein DegS 12 170 1.6E-46 T 12-10-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 HW35_07905 4e5efb53a979fda89045bad69a68433b 388 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 359 1.8E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_07905 4e5efb53a979fda89045bad69a68433b 388 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 378 1.8E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_07905 4e5efb53a979fda89045bad69a68433b 388 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 338 1.8E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_08885 d8126ec14332ade3bd29558064c7bbb7 183 Gene3D G3DSA:2.60.120.10 58 183 3.1E-45 T 12-10-2018 IPR014710 RmlC-like jelly roll fold HW35_08885 d8126ec14332ade3bd29558064c7bbb7 183 Pfam PF07883 Cupin domain 83 158 1.2E-14 T 12-10-2018 IPR013096 Cupin 2, conserved barrel HW35_08885 d8126ec14332ade3bd29558064c7bbb7 183 SUPERFAMILY SSF51182 27 163 3.11E-27 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily HW35_07010 ab4a9c040343a2c66aad5949de330e00 332 Pfam PF01551 Peptidase family M23 207 305 9.9E-20 T 12-10-2018 IPR016047 Peptidase M23 HW35_07010 ab4a9c040343a2c66aad5949de330e00 332 Gene3D G3DSA:2.70.70.10 113 329 9.1E-57 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_07010 ab4a9c040343a2c66aad5949de330e00 332 SUPERFAMILY SSF51261 123 318 1.15E-32 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 SUPERFAMILY SSF158472 188 236 8.76E-9 T 12-10-2018 HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 SMART SM00304 187 239 2.4E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 468 1.8E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 Gene3D G3DSA:1.10.287.130 243 313 9.1E-20 T 12-10-2018 HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 Gene3D G3DSA:1.20.1480.50 150 242 6.3E-12 T 12-10-2018 HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 SMART SM00388 247 313 4.5E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 7.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 7.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 7.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 SMART SM00387 358 470 3.1E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 SUPERFAMILY SSF55874 302 468 4.06E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 SUPERFAMILY SSF47384 230 314 4.71E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 Gene3D G3DSA:3.30.565.10 315 472 2.4E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 Pfam PF00672 HAMP domain 190 235 6.3E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_02130 92da19a84013ad8837fdae9fc24deecb 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 312 4.2E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HW35_13505 df46cbb6d57479ed166be7d5f7df078e 218 SUPERFAMILY SSF55874 91 217 1.01E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_13505 df46cbb6d57479ed166be7d5f7df078e 218 Pfam PF07730 Histidine kinase 23 86 6.5E-8 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HW35_13505 df46cbb6d57479ed166be7d5f7df078e 218 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 126 217 2.0E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HW35_13505 df46cbb6d57479ed166be7d5f7df078e 218 Gene3D G3DSA:3.30.565.10 84 218 1.1E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HW35_00905 8a089e4b31642ddb1e01460465a6256b 198 Pfam PF00156 Phosphoribosyl transferase domain 33 157 6.7E-8 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HW35_00905 8a089e4b31642ddb1e01460465a6256b 198 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 188 8.6E-91 T 12-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 HW35_00905 8a089e4b31642ddb1e01460465a6256b 198 SUPERFAMILY SSF53271 1 188 5.84E-47 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_00905 8a089e4b31642ddb1e01460465a6256b 198 Gene3D G3DSA:3.40.50.2020 3 188 1.0E-54 T 12-10-2018 HW35_00905 8a089e4b31642ddb1e01460465a6256b 198 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 43.728 T 12-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 HW35_04395 4af9c79efb96d41de60a46b33b3c2a91 371 Gene3D G3DSA:3.30.70.120 132 241 4.8E-45 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HW35_04395 4af9c79efb96d41de60a46b33b3c2a91 371 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 348 3.6E-82 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HW35_04395 4af9c79efb96d41de60a46b33b3c2a91 371 SUPERFAMILY SSF102705 6 370 4.84E-136 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily HW35_04395 4af9c79efb96d41de60a46b33b3c2a91 371 PIRSF PIRSF037489 2 371 3.9E-156 T 12-10-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria HW35_04395 4af9c79efb96d41de60a46b33b3c2a91 371 Gene3D G3DSA:3.40.1390.30 5 126 1.5E-41 T 12-10-2018 HW35_04395 4af9c79efb96d41de60a46b33b3c2a91 371 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 367 6.7E-90 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HW35_00430 8e29b84b94559859553d51c7b4c80836 206 SUPERFAMILY SSF141371 113 199 1.94E-5 T 12-10-2018 HW35_00430 8e29b84b94559859553d51c7b4c80836 206 Pfam PF07238 PilZ domain 94 196 1.6E-11 T 12-10-2018 IPR009875 PilZ domain GO:0035438 HW35_00430 8e29b84b94559859553d51c7b4c80836 206 Gene3D G3DSA:2.40.10.220 89 202 1.0E-10 T 12-10-2018 HW35_00430 8e29b84b94559859553d51c7b4c80836 206 Pfam PF12945 Flagellar protein YcgR 4 85 1.6E-12 T 12-10-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal HW35_16165 674ba4550ba8877bea23f25a3ae4638b 143 Gene3D G3DSA:1.20.1500.10 3 126 8.7E-29 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily HW35_16165 674ba4550ba8877bea23f25a3ae4638b 143 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 10 115 1.7E-18 T 12-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA HW35_16165 674ba4550ba8877bea23f25a3ae4638b 143 SUPERFAMILY SSF158622 4 126 4.71E-36 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily HW35_13235 5c477f35fd088ce94e200ec6b236abc4 92 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 61 2.3E-13 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HW35_13235 5c477f35fd088ce94e200ec6b236abc4 92 SUPERFAMILY SSF52794 3 90 1.28E-20 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_13235 5c477f35fd088ce94e200ec6b236abc4 92 Gene3D G3DSA:3.40.50.2300 2 92 1.2E-28 T 12-10-2018 HW35_12020 6657936623ce9dcceebddbd06e7951f2 320 Pfam PF01497 Periplasmic binding protein 64 297 2.2E-35 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain HW35_12020 6657936623ce9dcceebddbd06e7951f2 320 Gene3D G3DSA:3.40.50.12260 192 296 5.8E-98 T 12-10-2018 HW35_12020 6657936623ce9dcceebddbd06e7951f2 320 Gene3D G3DSA:3.40.50.1980 56 314 5.8E-98 T 12-10-2018 HW35_12020 6657936623ce9dcceebddbd06e7951f2 320 SUPERFAMILY SSF53807 45 306 3.81E-70 T 12-10-2018 HW35_03470 c18c0334f1368499d6f942a01c7a8313 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_03470 c18c0334f1368499d6f942a01c7a8313 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_03470 c18c0334f1368499d6f942a01c7a8313 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 1.7E-6 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_03470 c18c0334f1368499d6f942a01c7a8313 420 Pfam PF08388 Group II intron, maturase-specific domain 288 360 4.2E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_03470 c18c0334f1368499d6f942a01c7a8313 420 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 2.2E-131 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_03470 c18c0334f1368499d6f942a01c7a8313 420 SUPERFAMILY SSF56672 23 346 1.59E-58 T 12-10-2018 HW35_03470 c18c0334f1368499d6f942a01c7a8313 420 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 3.1E-49 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_03210 0f20e319b77308c44c9d140e5d95e490 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 97 8.0E-41 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HW35_03210 0f20e319b77308c44c9d140e5d95e490 127 Gene3D G3DSA:2.40.40.20 1 125 6.2E-55 T 12-10-2018 HW35_03210 0f20e319b77308c44c9d140e5d95e490 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 73.858 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HW35_03210 0f20e319b77308c44c9d140e5d95e490 127 Pfam PF02261 Aspartate decarboxylase 1 114 3.1E-53 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HW35_03210 0f20e319b77308c44c9d140e5d95e490 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 6.4E-61 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HW35_03210 0f20e319b77308c44c9d140e5d95e490 127 PIRSF PIRSF006246 1 126 3.7E-54 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HW35_03210 0f20e319b77308c44c9d140e5d95e490 127 SUPERFAMILY SSF50692 1 121 4.56E-51 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily HW35_00555 a816492b1fa3771b02d8105a9c446593 311 Gene3D G3DSA:3.10.310.20 190 309 9.5E-40 T 12-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HW35_00555 a816492b1fa3771b02d8105a9c446593 311 Pfam PF02833 DHHA2 domain 183 306 1.1E-22 T 12-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HW35_00555 a816492b1fa3771b02d8105a9c446593 311 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 47.678 T 12-10-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HW35_00555 a816492b1fa3771b02d8105a9c446593 311 SUPERFAMILY SSF64182 1 307 3.66E-87 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily HW35_00555 a816492b1fa3771b02d8105a9c446593 311 Gene3D G3DSA:3.90.1640.10 1 188 7.8E-84 T 12-10-2018 HW35_00555 a816492b1fa3771b02d8105a9c446593 311 SMART SM01131 181 307 3.3E-57 T 12-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HW35_00555 a816492b1fa3771b02d8105a9c446593 311 Pfam PF01368 DHH family 3 146 1.4E-32 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HW35_15925 7de1541b02436fadbb5c4a54161cb025 184 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 174 1.5E-48 T 12-10-2018 IPR023635 Peptide deformylase HW35_15925 7de1541b02436fadbb5c4a54161cb025 184 Pfam PF01327 Polypeptide deformylase 5 171 2.9E-47 T 12-10-2018 IPR023635 Peptide deformylase HW35_15925 7de1541b02436fadbb5c4a54161cb025 184 SUPERFAMILY SSF56420 2 178 1.31E-60 T 12-10-2018 IPR036821 Peptide deformylase superfamily HW35_15925 7de1541b02436fadbb5c4a54161cb025 184 Hamap MF_00163 Peptide deformylase [def]. 3 182 27.639 T 12-10-2018 IPR023635 Peptide deformylase HW35_15925 7de1541b02436fadbb5c4a54161cb025 184 PRINTS PR01576 Peptide deformylase signature 140 169 2.5E-31 T 12-10-2018 IPR023635 Peptide deformylase HW35_15925 7de1541b02436fadbb5c4a54161cb025 184 PRINTS PR01576 Peptide deformylase signature 108 119 2.5E-31 T 12-10-2018 IPR023635 Peptide deformylase HW35_15925 7de1541b02436fadbb5c4a54161cb025 184 PRINTS PR01576 Peptide deformylase signature 121 139 2.5E-31 T 12-10-2018 IPR023635 Peptide deformylase HW35_15925 7de1541b02436fadbb5c4a54161cb025 184 PRINTS PR01576 Peptide deformylase signature 47 76 2.5E-31 T 12-10-2018 IPR023635 Peptide deformylase HW35_15925 7de1541b02436fadbb5c4a54161cb025 184 Gene3D G3DSA:3.90.45.10 1 184 2.8E-66 T 12-10-2018 IPR036821 Peptide deformylase superfamily HW35_15925 7de1541b02436fadbb5c4a54161cb025 184 PIRSF PIRSF004749 2 184 5.7E-49 T 12-10-2018 IPR023635 Peptide deformylase HW35_01555 c0b59043a86007603e9c8ef76b6fde7f 434 Pfam PF03796 DnaB-like helicase C terminal domain 175 432 1.9E-94 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 HW35_01555 c0b59043a86007603e9c8ef76b6fde7f 434 Gene3D G3DSA:1.10.860.10 2 146 4.4E-39 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal HW35_01555 c0b59043a86007603e9c8ef76b6fde7f 434 Pfam PF00772 DnaB-like helicase N terminal domain 8 106 1.7E-20 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HW35_01555 c0b59043a86007603e9c8ef76b6fde7f 434 SUPERFAMILY SSF52540 175 429 5.56E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_01555 c0b59043a86007603e9c8ef76b6fde7f 434 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 8 434 3.1E-129 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 HW35_01555 c0b59043a86007603e9c8ef76b6fde7f 434 Gene3D G3DSA:3.40.50.300 151 434 8.3E-98 T 12-10-2018 HW35_01555 c0b59043a86007603e9c8ef76b6fde7f 434 SUPERFAMILY SSF48024 7 114 3.01E-20 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 HW35_12035 1e801c892512591f92cf4eb23c5c7141 196 Pfam PF02632 BioY family 34 180 1.3E-35 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 HW35_12035 1e801c892512591f92cf4eb23c5c7141 196 Gene3D G3DSA:1.10.1760.20 1 189 5.0E-48 T 12-10-2018 HW35_12035 1e801c892512591f92cf4eb23c5c7141 196 PIRSF PIRSF016661 1 185 5.5E-45 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 HW35_17265 64dbfaae531d5a8ec98796b5335cf9f1 157 PIRSF PIRSF021441 1 157 1.4E-67 T 12-10-2018 IPR031306 CcdC protein HW35_17265 64dbfaae531d5a8ec98796b5335cf9f1 157 Pfam PF07301 Protein of unknown function (DUF1453) 6 149 1.1E-59 T 12-10-2018 IPR009916 Protein of unknown function DUF1453 HW35_09525 dffe42bbfdb6c0e56c06b27109b85a56 235 Pfam PF00005 ABC transporter 17 162 1.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_09525 dffe42bbfdb6c0e56c06b27109b85a56 235 Gene3D G3DSA:3.40.50.300 1 235 1.0E-66 T 12-10-2018 HW35_09525 dffe42bbfdb6c0e56c06b27109b85a56 235 SUPERFAMILY SSF52540 2 233 1.33E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09525 dffe42bbfdb6c0e56c06b27109b85a56 235 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_09525 dffe42bbfdb6c0e56c06b27109b85a56 235 SMART SM00382 26 211 1.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_09525 dffe42bbfdb6c0e56c06b27109b85a56 235 PIRSF PIRSF039137 1 235 4.9E-114 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 HW35_02485 a82c9471706c52b7c082e76890b5ad23 80 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 1 47 5.0E-14 T 12-10-2018 IPR005370 Uncharacterised protein family UPF0180 HW35_02485 a82c9471706c52b7c082e76890b5ad23 80 Hamap MF_00506 UPF0180 protein . 1 79 28.33 T 12-10-2018 IPR005370 Uncharacterised protein family UPF0180 HW35_02485 a82c9471706c52b7c082e76890b5ad23 80 Pfam PF03698 Uncharacterised protein family (UPF0180) 3 78 2.4E-33 T 12-10-2018 IPR005370 Uncharacterised protein family UPF0180 HW35_00135 ecd002d81592757ae99c616c0492929f 194 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 178 4.8E-63 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 HW35_00135 ecd002d81592757ae99c616c0492929f 194 Gene3D G3DSA:1.20.1200.10 12 194 4.5E-66 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 HW35_00135 ecd002d81592757ae99c616c0492929f 194 Pfam PF01923 Cobalamin adenosyltransferase 3 167 2.3E-57 T 12-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 HW35_00135 ecd002d81592757ae99c616c0492929f 194 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 180 1.0E-57 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 HW35_00135 ecd002d81592757ae99c616c0492929f 194 SUPERFAMILY SSF89028 1 179 1.49E-62 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 Gene3D G3DSA:3.30.1360.120 6 238 5.5E-95 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 Gene3D G3DSA:4.10.1250.10 239 282 7.5E-19 T 12-10-2018 HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 SUPERFAMILY SSF103025 3 283 1.57E-103 T 12-10-2018 HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 Gene3D G3DSA:2.40.30.110 283 365 6.1E-33 T 12-10-2018 HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 SUPERFAMILY SSF101790 276 366 2.62E-27 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 PIRSF PIRSF006487 1 367 2.7E-111 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 365 49.575 T 12-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 365 6.6E-147 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 270 359 3.7E-28 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 261 5.5E-101 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain HW35_04155 cb11809c8519ce95e27e4ef0302f5cd1 367 Gene3D G3DSA:3.30.70.1400 53 138 5.5E-95 T 12-10-2018 HW35_14945 a38b415e15b921aaaf7cf3b3fd0fe240 246 SMART SM00382 28 213 9.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_14945 a38b415e15b921aaaf7cf3b3fd0fe240 246 SUPERFAMILY SSF52540 3 232 1.52E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14945 a38b415e15b921aaaf7cf3b3fd0fe240 246 Pfam PF00005 ABC transporter 19 162 6.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_14945 a38b415e15b921aaaf7cf3b3fd0fe240 246 Gene3D G3DSA:3.40.50.300 1 245 1.5E-62 T 12-10-2018 HW35_14325 5b363e3d99f2d1cc4ad5fc5d1c11041e 116 Hamap MF_01502 UPF0295 protein . 1 115 37.098 T 12-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 HW35_14325 5b363e3d99f2d1cc4ad5fc5d1c11041e 116 Pfam PF11023 Zinc-ribbon containing domain 3 113 3.1E-61 T 12-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 HW35_14325 5b363e3d99f2d1cc4ad5fc5d1c11041e 116 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 3 113 1.0E-48 T 12-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 HW35_15280 60160727535d0325399b88a052c7106c 321 SUPERFAMILY SSF161098 92 307 1.27E-18 T 12-10-2018 IPR035906 MetI-like superfamily HW35_15280 60160727535d0325399b88a052c7106c 321 Gene3D G3DSA:1.10.3720.10 87 313 7.4E-20 T 12-10-2018 IPR035906 MetI-like superfamily HW35_15280 60160727535d0325399b88a052c7106c 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 319 5.8E-41 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_17090 d5469843186535955a99e806312f4c36 141 Pfam PF07681 DoxX 9 87 2.7E-18 T 12-10-2018 IPR032808 DoxX family HW35_16965 c9a27dff01b505f4e5846b2be86dd8c1 81 Gene3D G3DSA:1.10.760.20 1 81 7.1E-32 T 12-10-2018 IPR038292 YmfJ/YflH superfamily HW35_16965 c9a27dff01b505f4e5846b2be86dd8c1 81 Pfam PF11588 Protein of unknown function (DUF3243) 3 80 1.1E-34 T 12-10-2018 IPR021637 Protein of unknown function DUF3243 HW35_16965 c9a27dff01b505f4e5846b2be86dd8c1 81 PIRSF PIRSF004764 1 81 4.0E-27 T 12-10-2018 IPR024702 Uncharacterised conserved protein YmfJ HW35_00810 46369bb04d7eeb9f7fca5e696bc290d1 296 SUPERFAMILY SSF103481 200 292 1.57E-11 T 12-10-2018 HW35_00810 46369bb04d7eeb9f7fca5e696bc290d1 296 SUPERFAMILY SSF103481 44 149 2.68E-9 T 12-10-2018 HW35_00810 46369bb04d7eeb9f7fca5e696bc290d1 296 Pfam PF00892 EamA-like transporter family 7 147 1.1E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_00810 46369bb04d7eeb9f7fca5e696bc290d1 296 Pfam PF00892 EamA-like transporter family 162 292 1.7E-21 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 Gene3D G3DSA:3.40.50.1000 317 586 1.1E-89 T 12-10-2018 IPR023214 HAD superfamily HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 Pfam PF00122 E1-E2 ATPase 135 316 2.5E-52 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00941 Cadmium-transporting ATPase signature 201 217 1.2E-13 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00941 Cadmium-transporting ATPase signature 220 234 1.2E-13 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00941 Cadmium-transporting ATPase signature 140 156 1.2E-13 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00941 Cadmium-transporting ATPase signature 120 140 1.2E-13 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00941 Cadmium-transporting ATPase signature 65 77 1.2E-13 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 558 570 2.7E-29 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 2.7E-29 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 460 471 2.7E-29 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 554 2.7E-29 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 185 199 2.7E-29 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 482 492 2.7E-29 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 SUPERFAMILY SSF56784 335 634 3.07E-60 T 12-10-2018 IPR036412 HAD-like superfamily HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 ProSitePatterns PS01229 Hypothetical cof family signature 2. 535 557 - T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 SUPERFAMILY SSF81665 87 614 9.55E-19 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 338 344 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 Pfam PF00702 haloacid dehalogenase-like hydrolase 334 549 2.2E-40 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 Gene3D G3DSA:2.70.150.20 129 240 2.5E-37 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 70 637 2.4E-122 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 108 616 1.3E-89 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 85 424 1.1E-98 T 12-10-2018 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 85 637 1.1E-191 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 SUPERFAMILY SSF81653 138 235 4.71E-27 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 HW35_13725 dd3e297d93ee45bcedb89498b5ede454 639 Gene3D G3DSA:3.40.1110.10 347 467 1.1E-89 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HW35_00980 3e13c627701bb18879e6e5af0fbada3d 178 ProSitePatterns PS00194 Thioredoxin family active site. 73 91 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 HW35_00980 3e13c627701bb18879e6e5af0fbada3d 178 SUPERFAMILY SSF52833 43 174 6.24E-42 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_00980 3e13c627701bb18879e6e5af0fbada3d 178 Pfam PF00578 AhpC/TSA family 45 159 3.1E-35 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HW35_00980 3e13c627701bb18879e6e5af0fbada3d 178 Gene3D G3DSA:3.40.30.10 17 178 1.4E-49 T 12-10-2018 HW35_04640 2ff30b56ce541377311b1229d1445ca0 189 Pfam PF01467 Cytidylyltransferase-like 6 162 4.3E-35 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HW35_04640 2ff30b56ce541377311b1229d1445ca0 189 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 187 1.8E-57 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 HW35_04640 2ff30b56ce541377311b1229d1445ca0 189 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 67 5.2E-11 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HW35_04640 2ff30b56ce541377311b1229d1445ca0 189 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 188 32.893 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 HW35_04640 2ff30b56ce541377311b1229d1445ca0 189 SUPERFAMILY SSF52374 1 188 8.59E-57 T 12-10-2018 HW35_04640 2ff30b56ce541377311b1229d1445ca0 189 Gene3D G3DSA:3.40.50.620 1 188 1.4E-68 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 PIRSF PIRSF006092 1 158 3.5E-55 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 7.6E-33 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 SUPERFAMILY SSF46557 6 80 2.88E-28 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 33.737 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 123 139 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 158 1.7E-30 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 Gene3D G3DSA:3.10.50.30 81 158 3.5E-29 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 4.8E-62 T 12-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 Gene3D G3DSA:1.10.287.180 5 78 1.1E-32 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 HW35_04730 d4b5d4b0e65ecd16b04c8cc71533abe2 158 SUPERFAMILY SSF54534 85 157 1.57E-23 T 12-10-2018 HW35_13310 7c15829b0612e990593dc091d768f333 555 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 462 473 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HW35_13310 7c15829b0612e990593dc091d768f333 555 SUPERFAMILY SSF143975 1 373 7.98E-143 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HW35_13310 7c15829b0612e990593dc091d768f333 555 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 554 6.1E-252 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HW35_13310 7c15829b0612e990593dc091d768f333 555 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 554 47.623 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HW35_13310 7c15829b0612e990593dc091d768f333 555 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HW35_13310 7c15829b0612e990593dc091d768f333 555 Gene3D G3DSA:3.50.30.80 374 525 2.0E-55 T 12-10-2018 HW35_13310 7c15829b0612e990593dc091d768f333 555 Pfam PF00920 Dehydratase family 31 550 1.5E-229 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HW35_13310 7c15829b0612e990593dc091d768f333 555 SUPERFAMILY SSF52016 374 554 3.45E-63 T 12-10-2018 HW35_09055 63dd7ce1336bfd6bb3c75d4e50482152 334 Pfam PF00146 NADH dehydrogenase 23 327 2.6E-126 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09055 63dd7ce1336bfd6bb3c75d4e50482152 334 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 14 333 25.337 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09055 63dd7ce1336bfd6bb3c75d4e50482152 334 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 216 229 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_16565 81efb6f5977ebd3423b380b4796a9761 358 PIRSF PIRSF006004 7 358 1.8E-140 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 HW35_16565 81efb6f5977ebd3423b380b4796a9761 358 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 12 354 74.794 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 HW35_16565 81efb6f5977ebd3423b380b4796a9761 358 Gene3D G3DSA:1.10.150.530 12 73 4.1E-24 T 12-10-2018 HW35_16565 81efb6f5977ebd3423b380b4796a9761 358 Pfam PF04055 Radical SAM superfamily 115 288 2.3E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_16565 81efb6f5977ebd3423b380b4796a9761 358 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 10 357 8.7E-166 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 HW35_16565 81efb6f5977ebd3423b380b4796a9761 358 Pfam PF13394 4Fe-4S single cluster domain 120 223 4.4E-6 T 12-10-2018 HW35_16565 81efb6f5977ebd3423b380b4796a9761 358 SUPERFAMILY SSF102114 99 311 5.89E-15 T 12-10-2018 HW35_16565 81efb6f5977ebd3423b380b4796a9761 358 Gene3D G3DSA:3.20.20.70 75 339 2.1E-100 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_08400 d3ede030bba244cd63cedaac5f763797 310 Pfam PF02603 HPr Serine kinase N terminus 4 129 1.3E-37 T 12-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 HW35_08400 d3ede030bba244cd63cedaac5f763797 310 Pfam PF07475 HPr Serine kinase C-terminal domain 132 300 9.1E-62 T 12-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 HW35_08400 d3ede030bba244cd63cedaac5f763797 310 Gene3D G3DSA:3.40.1390.20 3 132 9.2E-41 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily HW35_08400 d3ede030bba244cd63cedaac5f763797 310 SUPERFAMILY SSF53795 135 302 4.88E-33 T 12-10-2018 HW35_08400 d3ede030bba244cd63cedaac5f763797 310 Gene3D G3DSA:3.40.50.300 133 310 5.5E-57 T 12-10-2018 HW35_08400 d3ede030bba244cd63cedaac5f763797 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 4 304 3.4E-104 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 HW35_08400 d3ede030bba244cd63cedaac5f763797 310 SUPERFAMILY SSF75138 2 131 5.1E-35 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily HW35_08400 d3ede030bba244cd63cedaac5f763797 310 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 308 33.971 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 HW35_13125 42aa961ba5b91e00834bfe5eec3fc1e8 130 Gene3D G3DSA:1.10.490.10 5 130 5.5E-45 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 HW35_13125 42aa961ba5b91e00834bfe5eec3fc1e8 130 Pfam PF01152 Bacterial-like globin 7 107 4.5E-31 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 HW35_13125 42aa961ba5b91e00834bfe5eec3fc1e8 130 SUPERFAMILY SSF46458 7 125 7.2E-35 T 12-10-2018 IPR009050 Globin-like superfamily HW35_03255 b3bc4a07d674552b41a711c57947aa4d 115 PIRSF PIRSF029904 2 112 4.5E-54 T 12-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD HW35_03255 b3bc4a07d674552b41a711c57947aa4d 115 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 26 105 6.4E-21 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core HW35_03255 b3bc4a07d674552b41a711c57947aa4d 115 SUPERFAMILY SSF101386 7 105 1.29E-28 T 12-10-2018 HW35_03255 b3bc4a07d674552b41a711c57947aa4d 115 Gene3D G3DSA:1.10.287.1080 2 114 2.6E-36 T 12-10-2018 HW35_08365 03ce486d785dd5625850701bcc82e06a 181 Pfam PF01380 SIS domain 29 131 3.0E-18 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HW35_08365 03ce486d785dd5625850701bcc82e06a 181 SUPERFAMILY SSF53697 5 180 1.71E-37 T 12-10-2018 HW35_08365 03ce486d785dd5625850701bcc82e06a 181 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 5 181 5.7E-66 T 12-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 HW35_08365 03ce486d785dd5625850701bcc82e06a 181 Gene3D G3DSA:3.40.50.10490 2 181 7.4E-51 T 12-10-2018 HW35_07385 3b0ea1caa6e1a76f73960331ac838aad 242 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 123 216 1.6E-6 T 12-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family HW35_07385 3b0ea1caa6e1a76f73960331ac838aad 242 SUPERFAMILY SSF54001 108 239 9.61E-17 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily HW35_01360 4904713b736f574f99a1fbfc6eb85225 185 Pfam PF03358 NADPH-dependent FMN reductase 3 143 4.6E-26 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HW35_01360 4904713b736f574f99a1fbfc6eb85225 185 Gene3D G3DSA:3.40.50.360 2 181 6.2E-44 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_01360 4904713b736f574f99a1fbfc6eb85225 185 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 3 172 9.3E-61 T 12-10-2018 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 HW35_01360 4904713b736f574f99a1fbfc6eb85225 185 SUPERFAMILY SSF52218 3 170 7.76E-31 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_01490 ba9d6a6f0ef6efa36ca952f6b1e20b3e 254 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 182 199 5.4E-37 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HW35_01490 ba9d6a6f0ef6efa36ca952f6b1e20b3e 254 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 224 244 5.4E-37 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HW35_01490 ba9d6a6f0ef6efa36ca952f6b1e20b3e 254 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 24 38 5.4E-37 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HW35_01490 ba9d6a6f0ef6efa36ca952f6b1e20b3e 254 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 72 92 5.4E-37 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HW35_01490 ba9d6a6f0ef6efa36ca952f6b1e20b3e 254 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 201 219 5.4E-37 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HW35_01490 ba9d6a6f0ef6efa36ca952f6b1e20b3e 254 Pfam PF01555 DNA methylase 25 240 5.6E-48 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 HW35_01490 ba9d6a6f0ef6efa36ca952f6b1e20b3e 254 Gene3D G3DSA:3.40.50.150 7 245 5.3E-62 T 12-10-2018 HW35_01490 ba9d6a6f0ef6efa36ca952f6b1e20b3e 254 SUPERFAMILY SSF53335 5 246 3.84E-62 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_01490 ba9d6a6f0ef6efa36ca952f6b1e20b3e 254 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 28 34 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HW35_13730 9135956a4a1e06c9373017f216305deb 393 Pfam PF00083 Sugar (and other) transporter 39 184 1.4E-6 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 HW35_13730 9135956a4a1e06c9373017f216305deb 393 ProSitePatterns PS00216 Sugar transport proteins signature 1. 259 274 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HW35_13730 9135956a4a1e06c9373017f216305deb 393 Pfam PF07690 Major Facilitator Superfamily 214 379 1.9E-22 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_13730 9135956a4a1e06c9373017f216305deb 393 Gene3D G3DSA:1.20.1250.20 204 388 3.2E-22 T 12-10-2018 HW35_13730 9135956a4a1e06c9373017f216305deb 393 SUPERFAMILY SSF103473 5 382 4.97E-54 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_13730 9135956a4a1e06c9373017f216305deb 393 Gene3D G3DSA:1.20.1250.20 3 187 4.1E-28 T 12-10-2018 HW35_08085 50ecb2b6530efc60e5f4b00860f9d6c1 393 PIRSF PIRSF026508 25 393 1.3E-122 T 12-10-2018 IPR008863 Toxic anion resistance HW35_08085 50ecb2b6530efc60e5f4b00860f9d6c1 393 Pfam PF05816 Toxic anion resistance protein (TelA) 61 388 9.9E-127 T 12-10-2018 IPR008863 Toxic anion resistance HW35_10420 03530cb234dbf21165638588c57daddc 196 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HW35_10420 03530cb234dbf21165638588c57daddc 196 Gene3D G3DSA:1.10.357.10 5 196 1.6E-48 T 12-10-2018 HW35_10420 03530cb234dbf21165638588c57daddc 196 SUPERFAMILY SSF48498 78 195 6.43E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily HW35_10420 03530cb234dbf21165638588c57daddc 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 1.2E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_10420 03530cb234dbf21165638588c57daddc 196 SUPERFAMILY SSF46689 4 80 4.1E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_10420 03530cb234dbf21165638588c57daddc 196 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 86 195 4.9E-20 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal HW35_05995 3da71c67c2eb445b2e1bd77816ee3e93 257 Gene3D G3DSA:3.90.1200.10 75 252 3.1E-23 T 12-10-2018 HW35_05995 3da71c67c2eb445b2e1bd77816ee3e93 257 Pfam PF01636 Phosphotransferase enzyme family 35 215 6.2E-25 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase HW35_05995 3da71c67c2eb445b2e1bd77816ee3e93 257 SUPERFAMILY SSF56112 9 225 4.52E-32 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_05845 6130a87e213cf84df475a12c80c5ec8e 68 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HW35_05845 6130a87e213cf84df475a12c80c5ec8e 68 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HW35_05845 6130a87e213cf84df475a12c80c5ec8e 68 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 1.2E-23 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 HW35_05845 6130a87e213cf84df475a12c80c5ec8e 68 Gene3D G3DSA:1.10.8.910 8 68 8.8E-32 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 20.317 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 12-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 SUPERFAMILY SSF47928 2 105 4.84E-23 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 PRINTS PR00125 ATP synthase delta subunit signature 151 169 1.0E-26 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 PRINTS PR00125 ATP synthase delta subunit signature 136 151 1.0E-26 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 PRINTS PR00125 ATP synthase delta subunit signature 6 25 1.0E-26 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 PRINTS PR00125 ATP synthase delta subunit signature 74 85 1.0E-26 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 PRINTS PR00125 ATP synthase delta subunit signature 85 99 1.0E-26 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 Gene3D G3DSA:1.10.520.20 6 97 1.2E-11 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 176 9.9E-49 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_09100 0cdc5286b32bc3f3167da2568c39e7e5 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 176 1.4E-47 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HW35_16535 64c3b86c4b64d50d1748987c293aa67d 72 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 8.6E-18 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_16535 64c3b86c4b64d50d1748987c293aa67d 72 Gene3D G3DSA:3.90.940.10 1 72 3.1E-18 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 HW35_16535 64c3b86c4b64d50d1748987c293aa67d 72 SMART SM01409 8 61 1.2E-13 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 HW35_16535 64c3b86c4b64d50d1748987c293aa67d 72 SUPERFAMILY SSF63562 1 68 2.27E-21 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 HW35_16535 64c3b86c4b64d50d1748987c293aa67d 72 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 13.85 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_16535 64c3b86c4b64d50d1748987c293aa67d 72 Pfam PF01192 RNA polymerase Rpb6 9 60 1.4E-12 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 HW35_06635 52175f14225417743f99791fcb79c640 80 Gene3D G3DSA:3.40.30.10 4 79 6.7E-18 T 12-10-2018 HW35_06635 52175f14225417743f99791fcb79c640 80 SUPERFAMILY SSF52833 5 75 3.21E-15 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_06635 52175f14225417743f99791fcb79c640 80 Pfam PF00462 Glutaredoxin 6 64 1.6E-13 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 HW35_05070 275ee4527563dcf3a2358f2db4d15a18 267 PIRSF PIRSF003092 1 267 3.8E-96 T 12-10-2018 IPR025501 ATP binding protein MinD HW35_05070 275ee4527563dcf3a2358f2db4d15a18 267 SUPERFAMILY SSF52540 5 263 1.22E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05070 275ee4527563dcf3a2358f2db4d15a18 267 Gene3D G3DSA:3.40.50.300 3 256 3.2E-71 T 12-10-2018 HW35_05070 275ee4527563dcf3a2358f2db4d15a18 267 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 264 1.1E-125 T 12-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 HW35_05070 275ee4527563dcf3a2358f2db4d15a18 267 Pfam PF13614 AAA domain 4 165 5.0E-27 T 12-10-2018 IPR025669 AAA domain HW35_15920 6c3348f0cc4e86c864c08cbf7d3bb7ec 69 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 6.0E-21 T 12-10-2018 IPR009907 Protein of unknown function DUF1447 HW35_15920 6c3348f0cc4e86c864c08cbf7d3bb7ec 69 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 1.2E-26 T 12-10-2018 IPR009907 Protein of unknown function DUF1447 HW35_15920 6c3348f0cc4e86c864c08cbf7d3bb7ec 69 Gene3D G3DSA:3.10.20.730 1 58 2.1E-25 T 12-10-2018 HW35_15920 6c3348f0cc4e86c864c08cbf7d3bb7ec 69 Hamap MF_01553 UPF0356 protein . 1 69 21.241 T 12-10-2018 IPR009907 Protein of unknown function DUF1447 HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 28 110 2.9E-21 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 523 621 3.8E-20 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 SMART SM00642 154 507 6.9E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 PIRSF PIRSF000463 1 632 3.2E-257 T 12-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 SUPERFAMILY SSF51445 87 511 1.39E-110 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 Gene3D G3DSA:2.60.40.10 4 124 2.6E-40 T 12-10-2018 IPR013783 Immunoglobulin-like fold HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 Gene3D G3DSA:2.60.40.1180 518 622 2.7E-33 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 Gene3D G3DSA:3.20.20.80 127 517 1.2E-148 T 12-10-2018 HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 SUPERFAMILY SSF81296 38 114 1.63E-10 T 12-10-2018 IPR014756 Immunoglobulin E-set HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 SUPERFAMILY SSF51011 519 623 1.41E-29 T 12-10-2018 HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 13 620 1.9E-257 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 7 622 39.887 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 Pfam PF00128 Alpha amylase, catalytic domain 179 276 1.1E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_06430 e8ca176e3e1c023f74befe616bf18c60 649 Pfam PF00128 Alpha amylase, catalytic domain 279 370 1.1E-4 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_12760 ae8069154933afd81bf9391b50ae64fd 75 SUPERFAMILY SSF47336 3 72 1.13E-10 T 12-10-2018 IPR036736 ACP-like superfamily HW35_12760 ae8069154933afd81bf9391b50ae64fd 75 Gene3D G3DSA:1.10.1200.10 1 72 1.0E-20 T 12-10-2018 IPR036736 ACP-like superfamily HW35_12760 ae8069154933afd81bf9391b50ae64fd 75 Pfam PF00550 Phosphopantetheine attachment site 5 67 6.4E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain HW35_04445 f1666011cd5f57ee942ebe6c20fbda1c 273 Pfam PF00665 Integrase core domain 109 223 3.6E-23 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_04445 f1666011cd5f57ee942ebe6c20fbda1c 273 Pfam PF13276 HTH-like domain 29 76 2.7E-18 T 12-10-2018 IPR025948 HTH-like domain HW35_04445 f1666011cd5f57ee942ebe6c20fbda1c 273 SUPERFAMILY SSF53098 100 263 8.04E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_04445 f1666011cd5f57ee942ebe6c20fbda1c 273 Gene3D G3DSA:3.30.420.10 99 271 1.7E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_13080 22d97482d962158628c0e5ff3180ed9d 267 SUPERFAMILY SSF55781 79 260 1.37E-56 T 12-10-2018 HW35_13080 22d97482d962158628c0e5ff3180ed9d 267 Gene3D G3DSA:1.10.10.10 12 85 2.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_13080 22d97482d962158628c0e5ff3180ed9d 267 SUPERFAMILY SSF46785 14 87 2.35E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13080 22d97482d962158628c0e5ff3180ed9d 267 Pfam PF09339 IclR helix-turn-helix domain 16 67 2.7E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 HW35_13080 22d97482d962158628c0e5ff3180ed9d 267 Pfam PF01614 Bacterial transcriptional regulator 131 256 4.4E-40 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal HW35_13080 22d97482d962158628c0e5ff3180ed9d 267 SMART SM00346 14 104 6.7E-27 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 HW35_13080 22d97482d962158628c0e5ff3180ed9d 267 Gene3D G3DSA:3.30.450.40 86 265 6.9E-68 T 12-10-2018 IPR029016 GAF-like domain superfamily HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 30 47 - T 12-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 Pfam PF00384 Molybdopterin oxidoreductase 84 517 1.7E-83 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 Gene3D G3DSA:3.40.228.10 169 369 3.1E-166 T 12-10-2018 HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 SUPERFAMILY SSF50692 577 722 7.91E-48 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 Pfam PF01568 Molydopterin dinucleotide binding domain 610 717 1.7E-30 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 Gene3D G3DSA:2.20.25.90 26 81 1.4E-12 T 12-10-2018 HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 SMART SM00926 25 81 2.8E-13 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 25 81 6.6E-14 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 Gene3D G3DSA:3.40.50.740 101 566 3.1E-166 T 12-10-2018 HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 SUPERFAMILY SSF53706 23 612 2.49E-183 T 12-10-2018 HW35_13475 1a17796ce00877897f7d057ee9707ba7 729 Gene3D G3DSA:2.40.40.20 600 723 3.0E-42 T 12-10-2018 HW35_15755 e0f0d4b72acb7a3f3c5e30d1f55fd237 170 Gene3D G3DSA:1.20.120.520 13 170 1.4E-34 T 12-10-2018 HW35_15755 e0f0d4b72acb7a3f3c5e30d1f55fd237 170 Pfam PF01814 Hemerythrin HHE cation binding domain 16 150 2.7E-18 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 HW35_08195 c77d7b083453944030d3fe2ae5b4ccba 271 Gene3D G3DSA:3.40.630.40 1 184 1.7E-54 T 12-10-2018 HW35_08195 c77d7b083453944030d3fe2ae5b4ccba 271 Gene3D G3DSA:3.30.70.1070 198 271 5.8E-16 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 HW35_08195 c77d7b083453944030d3fe2ae5b4ccba 271 SMART SM00646 63 175 3.0E-40 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HW35_08195 c77d7b083453944030d3fe2ae5b4ccba 271 SUPERFAMILY SSF110997 196 270 1.44E-14 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 HW35_08195 c77d7b083453944030d3fe2ae5b4ccba 271 Pfam PF05036 Sporulation related domain 196 269 2.6E-14 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 HW35_08195 c77d7b083453944030d3fe2ae5b4ccba 271 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 174 5.8E-47 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HW35_08195 c77d7b083453944030d3fe2ae5b4ccba 271 SUPERFAMILY SSF53187 1 176 7.53E-50 T 12-10-2018 HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 SUPERFAMILY SSF52540 4 415 8.59E-147 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 Pfam PF04851 Type III restriction enzyme, res subunit 14 139 2.1E-13 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 SMART SM00487 10 426 2.2E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 Hamap MF_00204 UvrABC system protein B [uvrB]. 4 659 45.565 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 657 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 SUPERFAMILY SSF46600 616 658 2.09E-10 T 12-10-2018 IPR036876 UVR domain superfamily HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 Gene3D G3DSA:3.40.50.300 267 414 5.3E-55 T 12-10-2018 HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 Pfam PF02151 UvrB/uvrC motif 624 658 2.3E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 Gene3D G3DSA:3.40.50.300 1 244 1.6E-83 T 12-10-2018 HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 Gene3D G3DSA:3.40.50.300 415 596 2.6E-56 T 12-10-2018 HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 Pfam PF12344 Ultra-violet resistance protein B 552 594 6.3E-23 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 Gene3D G3DSA:4.10.860.10 603 659 5.7E-5 T 12-10-2018 HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 SMART SM00490 460 546 1.1E-21 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 Pfam PF00271 Helicase conserved C-terminal domain 439 545 2.5E-19 T 12-10-2018 IPR001650 Helicase, C-terminal HW35_07715 01de284bad4ab384f2f34b6e5625a7db 660 SUPERFAMILY SSF52540 325 593 6.74E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13685 a323d7cee315d92a5fd29ae0ed09d06a 108 SUPERFAMILY SSF47413 1 63 6.7E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_13685 a323d7cee315d92a5fd29ae0ed09d06a 108 Pfam PF08671 Anti-repressor SinI 71 98 2.1E-16 T 12-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 HW35_13685 a323d7cee315d92a5fd29ae0ed09d06a 108 Gene3D G3DSA:1.10.260.40 1 108 2.7E-29 T 12-10-2018 HW35_13685 a323d7cee315d92a5fd29ae0ed09d06a 108 SMART SM00530 5 61 1.1E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_13685 a323d7cee315d92a5fd29ae0ed09d06a 108 Pfam PF01381 Helix-turn-helix 6 60 2.3E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_13685 a323d7cee315d92a5fd29ae0ed09d06a 108 SUPERFAMILY SSF47406 71 105 7.06E-15 T 12-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 HW35_04870 b10dd6d1f91b38c187861159c285efb5 255 SUPERFAMILY SSF69572 4 245 4.32E-62 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 HW35_04870 b10dd6d1f91b38c187861159c285efb5 255 Pfam PF00899 ThiF family 6 165 5.7E-38 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HW35_04870 b10dd6d1f91b38c187861159c285efb5 255 Gene3D G3DSA:3.40.50.720 1 255 1.2E-80 T 12-10-2018 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 PRINTS PR00171 Sugar transporter signature 384 396 5.4E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 PRINTS PR00171 Sugar transporter signature 21 31 5.4E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 PRINTS PR00171 Sugar transporter signature 276 286 5.4E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 PRINTS PR00171 Sugar transporter signature 120 139 5.4E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 PRINTS PR00171 Sugar transporter signature 361 382 5.4E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 4 455 4.0E-128 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 Gene3D G3DSA:1.20.1250.20 243 461 4.6E-66 T 12-10-2018 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 ProSitePatterns PS00217 Sugar transport proteins signature 2. 125 150 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 Gene3D G3DSA:1.20.1250.20 2 240 1.3E-64 T 12-10-2018 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 Pfam PF00083 Sugar (and other) transporter 14 459 4.4E-124 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 ProSitePatterns PS00216 Sugar transport proteins signature 1. 320 337 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HW35_11600 79b4717c5bd837ea54ae43b7e8fdd621 463 SUPERFAMILY SSF103473 7 456 5.89E-66 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_03335 df91e71b3a13a45e0ca7f905701e951a 356 Gene3D G3DSA:3.40.50.1970 2 171 1.3E-59 T 12-10-2018 HW35_03335 df91e71b3a13a45e0ca7f905701e951a 356 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 354 63.646 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HW35_03335 df91e71b3a13a45e0ca7f905701e951a 356 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 351 1.5E-114 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HW35_03335 df91e71b3a13a45e0ca7f905701e951a 356 Gene3D G3DSA:1.20.1090.10 172 356 4.1E-57 T 12-10-2018 HW35_03335 df91e71b3a13a45e0ca7f905701e951a 356 PIRSF PIRSF001455 3 356 4.5E-107 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HW35_03335 df91e71b3a13a45e0ca7f905701e951a 356 SUPERFAMILY SSF56796 7 354 1.27E-100 T 12-10-2018 HW35_03335 df91e71b3a13a45e0ca7f905701e951a 356 Pfam PF01761 3-dehydroquinate synthase 67 323 2.9E-97 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HW35_13835 d5853410a6bcd074e5ae12a54acbb1d1 104 SUPERFAMILY SSF46785 3 103 4.7E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13835 d5853410a6bcd074e5ae12a54acbb1d1 104 Pfam PF03551 Transcriptional regulator PadR-like family 14 87 7.8E-24 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal HW35_13835 d5853410a6bcd074e5ae12a54acbb1d1 104 Gene3D G3DSA:1.10.10.10 1 104 1.0E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_06010 6b07b3950f79a13767b8a9c8bfaa33de 190 Gene3D G3DSA:3.90.1140.10 6 190 2.6E-44 T 12-10-2018 HW35_06010 6b07b3950f79a13767b8a9c8bfaa33de 190 SUPERFAMILY SSF55144 6 187 2.27E-40 T 12-10-2018 IPR009097 Cyclic phosphodiesterase HW35_06010 6b07b3950f79a13767b8a9c8bfaa33de 190 Pfam PF13563 2'-5' RNA ligase superfamily 33 173 3.8E-15 T 12-10-2018 HW35_06010 6b07b3950f79a13767b8a9c8bfaa33de 190 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 6 187 9.7E-47 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 HW35_06010 6b07b3950f79a13767b8a9c8bfaa33de 190 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 5 187 22.341 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 HW35_16960 d18017a0049227f23c41e176edc45d6d 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 238 2.9E-52 T 12-10-2018 HW35_16960 d18017a0049227f23c41e176edc45d6d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16960 d18017a0049227f23c41e176edc45d6d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16960 d18017a0049227f23c41e176edc45d6d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 1.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16960 d18017a0049227f23c41e176edc45d6d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16960 d18017a0049227f23c41e176edc45d6d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_16960 d18017a0049227f23c41e176edc45d6d 240 Gene3D G3DSA:3.40.50.720 1 239 4.2E-71 T 12-10-2018 HW35_16960 d18017a0049227f23c41e176edc45d6d 240 SUPERFAMILY SSF51735 3 239 2.21E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_02190 634bd235cbefab57b2d275db47de2135 495 PIRSF PIRSF006060 2 487 8.8E-90 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HW35_02190 634bd235cbefab57b2d275db47de2135 495 Gene3D G3DSA:1.20.1740.10 18 485 1.2E-62 T 12-10-2018 HW35_02190 634bd235cbefab57b2d275db47de2135 495 ProSitePatterns PS00218 Amino acid permeases signature. 52 83 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 HW35_02190 634bd235cbefab57b2d275db47de2135 495 Pfam PF00324 Amino acid permease 27 477 3.9E-143 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Pfam PF04560 RNA polymerase Rpb2, domain 7 1070 1144 2.8E-27 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Gene3D G3DSA:3.90.1100.10 604 670 4.1E-19 T 12-10-2018 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 SUPERFAMILY SSF64484 14 1155 0.0 T 12-10-2018 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 2.5E-27 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Pfam PF04561 RNA polymerase Rpb2, domain 2 369 409 7.2E-7 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Gene3D G3DSA:2.40.50.100 671 750 5.8E-29 T 12-10-2018 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Pfam PF04563 RNA polymerase beta subunit 28 453 6.6E-30 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Pfam PF04565 RNA polymerase Rpb2, domain 3 468 536 1.0E-30 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1146 12.656 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 895 0.0 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Pfam PF00562 RNA polymerase Rpb2, domain 6 675 1068 1.1E-166 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Gene3D G3DSA:3.90.1800.10 1056 1109 1.1E-10 T 12-10-2018 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 ProSitePatterns PS01166 RNA polymerases beta chain signature. 921 933 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Gene3D G3DSA:3.90.1100.10 389 582 1.7E-74 T 12-10-2018 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Gene3D G3DSA:2.40.50.150 790 929 1.5E-61 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Pfam PF10385 RNA polymerase beta subunit external 1 domain 546 613 1.4E-25 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Gene3D G3DSA:3.90.1110.10 153 260 1.4E-7 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Gene3D G3DSA:3.90.1100.10 20 152 2.5E-53 T 12-10-2018 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Gene3D G3DSA:2.40.270.10 980 1046 4.4E-25 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_10675 2bc90d198da884808756ce8d638e160b 1186 Gene3D G3DSA:2.40.270.10 751 789 5.9E-7 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HW35_14590 05f1dde75c607a87625e49bfed094dda 157 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 34.917 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 HW35_14590 05f1dde75c607a87625e49bfed094dda 157 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 156 1.1E-66 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 HW35_14590 05f1dde75c607a87625e49bfed094dda 157 SUPERFAMILY SSF75217 3 155 1.05E-44 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases HW35_14590 05f1dde75c607a87625e49bfed094dda 157 Pfam PF00588 SpoU rRNA Methylase family 3 145 4.6E-35 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HW35_14590 05f1dde75c607a87625e49bfed094dda 157 Gene3D G3DSA:3.40.1280.10 1 157 1.1E-67 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HW35_14590 05f1dde75c607a87625e49bfed094dda 157 PIRSF PIRSF029256 2 157 2.8E-67 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 HW35_16750 e53834e92786d80036bd8b2d6b6a7f69 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 180 41.479 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 HW35_16750 e53834e92786d80036bd8b2d6b6a7f69 180 SUPERFAMILY SSF56235 3 179 6.72E-60 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HW35_16750 e53834e92786d80036bd8b2d6b6a7f69 180 Pfam PF00227 Proteasome subunit 5 178 1.0E-25 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 HW35_16750 e53834e92786d80036bd8b2d6b6a7f69 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 180 4.6E-83 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 HW35_16750 e53834e92786d80036bd8b2d6b6a7f69 180 Gene3D G3DSA:3.60.20.10 2 180 4.4E-68 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HW35_16750 e53834e92786d80036bd8b2d6b6a7f69 180 PIRSF PIRSF039093 1 180 2.8E-85 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 HW35_10055 aa716e92859297508e5a865d43754ef0 196 SUPERFAMILY SSF52317 3 190 4.59E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_10055 aa716e92859297508e5a865d43754ef0 196 Gene3D G3DSA:3.40.50.880 1 195 1.9E-72 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_10055 aa716e92859297508e5a865d43754ef0 196 PIRSF PIRSF005639 1 191 1.3E-74 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HW35_10055 aa716e92859297508e5a865d43754ef0 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 12-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HW35_10055 aa716e92859297508e5a865d43754ef0 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 186 37.753 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HW35_10055 aa716e92859297508e5a865d43754ef0 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 185 2.3E-85 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HW35_10055 aa716e92859297508e5a865d43754ef0 196 Pfam PF01174 SNO glutamine amidotransferase family 6 188 5.7E-78 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HW35_03455 22e1da413ddf94155fbe73455a424c9b 228 PIRSF PIRSF016933 1 221 1.1E-84 T 12-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 HW35_03455 22e1da413ddf94155fbe73455a424c9b 228 Pfam PF13367 Protease prsW family 28 198 1.9E-34 T 12-10-2018 IPR026898 Protease PrsW GO:0008233 HW35_04340 aadd542d74e41992a16447e226736148 369 SUPERFAMILY SSF51717 15 214 1.57E-17 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_04340 aadd542d74e41992a16447e226736148 369 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 350 6.9E-132 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HW35_04340 aadd542d74e41992a16447e226736148 369 PIRSF PIRSF004640 1 361 1.3E-156 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HW35_04340 aadd542d74e41992a16447e226736148 369 SUPERFAMILY SSF56014 263 358 8.58E-15 T 12-10-2018 HW35_04340 aadd542d74e41992a16447e226736148 369 Gene3D G3DSA:3.30.413.10 261 359 4.2E-36 T 12-10-2018 HW35_04340 aadd542d74e41992a16447e226736148 369 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 355 35.046 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HW35_04340 aadd542d74e41992a16447e226736148 369 Pfam PF04551 GcpE protein 10 351 9.8E-140 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HW35_04340 aadd542d74e41992a16447e226736148 369 Gene3D G3DSA:3.20.20.20 1 259 1.7E-109 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_03870 d8dee3fb623e6536a1240ab0b2b3d63b 732 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 42 562 1.1E-272 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_03870 d8dee3fb623e6536a1240ab0b2b3d63b 732 Pfam PF02310 B12 binding domain 598 708 4.3E-16 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 HW35_03870 d8dee3fb623e6536a1240ab0b2b3d63b 732 Pfam PF01642 Methylmalonyl-CoA mutase 43 556 8.7E-237 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_03870 d8dee3fb623e6536a1240ab0b2b3d63b 732 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 385 410 - T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_03870 d8dee3fb623e6536a1240ab0b2b3d63b 732 Gene3D G3DSA:3.40.50.280 562 725 1.8E-54 T 12-10-2018 HW35_03870 d8dee3fb623e6536a1240ab0b2b3d63b 732 Gene3D G3DSA:3.20.20.240 42 558 7.4E-240 T 12-10-2018 HW35_03870 d8dee3fb623e6536a1240ab0b2b3d63b 732 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 595 724 2.6E-61 T 12-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_03870 d8dee3fb623e6536a1240ab0b2b3d63b 732 SUPERFAMILY SSF52242 562 726 1.09E-58 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 HW35_03870 d8dee3fb623e6536a1240ab0b2b3d63b 732 SUPERFAMILY SSF51703 12 558 1.02E-222 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_07405 14b1da885cd3eaf867d6f76e3ea7a662 253 Gene3D G3DSA:3.20.20.70 2 252 1.2E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_07405 14b1da885cd3eaf867d6f76e3ea7a662 253 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 4.4E-62 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07405 14b1da885cd3eaf867d6f76e3ea7a662 253 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07405 14b1da885cd3eaf867d6f76e3ea7a662 253 Pfam PF00121 Triosephosphate isomerase 5 246 2.6E-97 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07405 14b1da885cd3eaf867d6f76e3ea7a662 253 SUPERFAMILY SSF51351 1 248 4.45E-97 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07405 14b1da885cd3eaf867d6f76e3ea7a662 253 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 62.548 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07465 37879679b3f1b373a2535760629f6086 180 TIGRFAM TIGR03585 PseH: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase 5 157 1.4E-38 T 12-10-2018 IPR020036 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase HW35_07465 37879679b3f1b373a2535760629f6086 180 Pfam PF13302 Acetyltransferase (GNAT) domain 5 135 2.3E-15 T 12-10-2018 IPR000182 GNAT domain HW35_07465 37879679b3f1b373a2535760629f6086 180 Gene3D G3DSA:3.40.630.30 1 171 8.7E-44 T 12-10-2018 HW35_07465 37879679b3f1b373a2535760629f6086 180 SUPERFAMILY SSF55729 4 159 3.99E-32 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 Gene3D G3DSA:3.50.50.60 131 248 2.1E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 SUPERFAMILY SSF51905 5 263 4.19E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 Gene3D G3DSA:3.50.50.60 5 293 2.1E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 289 1.4E-104 T 12-10-2018 HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 5 318 5.9E-144 T 12-10-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 1.1E-17 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.1E-17 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 298 1.1E-17 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 243 264 1.1E-17 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 1.1E-17 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 3.0E-13 T 12-10-2018 HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 3.0E-13 T 12-10-2018 HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.0E-13 T 12-10-2018 HW35_03465 5554c6b283eda45b63bd15c8e9bd9c9c 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 3.0E-13 T 12-10-2018 HW35_01830 ae068b72092940276eea3fbe8657d995 293 Pfam PF02361 Cobalt transport protein 9 218 8.3E-29 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component HW35_07340 2e066f6b1c4b7f5ac8cd7b3db35dc7f3 329 Pfam PF07731 Multicopper oxidase 225 328 1.4E-12 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 HW35_07340 2e066f6b1c4b7f5ac8cd7b3db35dc7f3 329 SUPERFAMILY SSF49503 80 198 2.09E-37 T 12-10-2018 IPR008972 Cupredoxin HW35_07340 2e066f6b1c4b7f5ac8cd7b3db35dc7f3 329 SUPERFAMILY SSF49503 198 328 1.04E-23 T 12-10-2018 IPR008972 Cupredoxin HW35_07340 2e066f6b1c4b7f5ac8cd7b3db35dc7f3 329 Gene3D G3DSA:2.60.40.420 203 328 1.2E-30 T 12-10-2018 IPR008972 Cupredoxin HW35_07340 2e066f6b1c4b7f5ac8cd7b3db35dc7f3 329 PRINTS PR00695 Copper containing nitrite reductase signature 163 178 2.4E-5 T 12-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 HW35_07340 2e066f6b1c4b7f5ac8cd7b3db35dc7f3 329 PRINTS PR00695 Copper containing nitrite reductase signature 180 196 2.4E-5 T 12-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 HW35_07340 2e066f6b1c4b7f5ac8cd7b3db35dc7f3 329 PRINTS PR00695 Copper containing nitrite reductase signature 106 122 2.4E-5 T 12-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 HW35_07340 2e066f6b1c4b7f5ac8cd7b3db35dc7f3 329 Gene3D G3DSA:2.60.40.420 50 201 5.4E-45 T 12-10-2018 IPR008972 Cupredoxin HW35_07340 2e066f6b1c4b7f5ac8cd7b3db35dc7f3 329 Pfam PF07732 Multicopper oxidase 93 198 4.7E-21 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 HW35_00090 3285d304891f5b8f154bb2830b544f44 352 Pfam PF01032 FecCD transport family 24 343 7.6E-94 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 HW35_00090 3285d304891f5b8f154bb2830b544f44 352 SUPERFAMILY SSF81345 7 344 1.44E-82 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_00090 3285d304891f5b8f154bb2830b544f44 352 Gene3D G3DSA:1.10.3470.10 11 351 1.8E-103 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 Gene3D G3DSA:3.40.50.150 66 266 4.2E-66 T 12-10-2018 HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 SMART SM00138 3 264 3.2E-83 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 PRINTS PR00996 Glutamate methyltransferase family signature 60 72 8.3E-40 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 PRINTS PR00996 Glutamate methyltransferase family signature 133 149 8.3E-40 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 PRINTS PR00996 Glutamate methyltransferase family signature 204 218 8.3E-40 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 PRINTS PR00996 Glutamate methyltransferase family signature 99 119 8.3E-40 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 PRINTS PR00996 Glutamate methyltransferase family signature 24 37 8.3E-40 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 PRINTS PR00996 Glutamate methyltransferase family signature 223 246 8.3E-40 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 PIRSF PIRSF000410 1 268 1.1E-76 T 12-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 SUPERFAMILY SSF47757 7 66 3.4E-5 T 12-10-2018 HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 SUPERFAMILY SSF53335 67 257 4.14E-52 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_00205 63ea63dbebc4ebe4b6b84747ce1e5253 279 Pfam PF01739 CheR methyltransferase, SAM binding domain 67 260 8.0E-63 T 12-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal HW35_11280 00837071db7790bcea5e065cfb9497e4 558 Gene3D G3DSA:3.30.70.270 135 305 2.7E-53 T 12-10-2018 HW35_11280 00837071db7790bcea5e065cfb9497e4 558 SUPERFAMILY SSF141868 308 551 3.4E-86 T 12-10-2018 IPR035919 EAL domain superfamily HW35_11280 00837071db7790bcea5e065cfb9497e4 558 Gene3D G3DSA:3.30.450.20 7 134 6.8E-33 T 12-10-2018 HW35_11280 00837071db7790bcea5e065cfb9497e4 558 SMART SM00086 83 125 1.2E-8 T 12-10-2018 IPR001610 PAC motif HW35_11280 00837071db7790bcea5e065cfb9497e4 558 Pfam PF00563 EAL domain 308 539 7.6E-73 T 12-10-2018 IPR001633 EAL domain HW35_11280 00837071db7790bcea5e065cfb9497e4 558 SUPERFAMILY SSF55073 141 294 2.98E-46 T 12-10-2018 IPR029787 Nucleotide cyclase HW35_11280 00837071db7790bcea5e065cfb9497e4 558 SMART SM00267 125 292 4.9E-55 T 12-10-2018 IPR000160 GGDEF domain HW35_11280 00837071db7790bcea5e065cfb9497e4 558 SMART SM00052 302 544 7.6E-129 T 12-10-2018 IPR001633 EAL domain HW35_11280 00837071db7790bcea5e065cfb9497e4 558 SMART SM00091 9 78 0.0072 T 12-10-2018 IPR000014 PAS domain HW35_11280 00837071db7790bcea5e065cfb9497e4 558 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 137 287 2.3E-37 T 12-10-2018 IPR000160 GGDEF domain HW35_11280 00837071db7790bcea5e065cfb9497e4 558 Gene3D G3DSA:3.20.20.450 306 552 1.1E-98 T 12-10-2018 IPR035919 EAL domain superfamily HW35_11280 00837071db7790bcea5e065cfb9497e4 558 SUPERFAMILY SSF55785 23 122 1.01E-28 T 12-10-2018 IPR035965 PAS domain superfamily HW35_11280 00837071db7790bcea5e065cfb9497e4 558 Pfam PF00990 Diguanylate cyclase, GGDEF domain 137 285 7.3E-44 T 12-10-2018 IPR000160 GGDEF domain HW35_11280 00837071db7790bcea5e065cfb9497e4 558 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 131 1.1E-17 T 12-10-2018 IPR000014 PAS domain HW35_11280 00837071db7790bcea5e065cfb9497e4 558 Pfam PF13426 PAS domain 23 124 5.1E-15 T 12-10-2018 IPR000014 PAS domain HW35_16530 c7b2449f8817ed3c736af8e8dda59a2f 204 SMART SM00072 4 187 1.8E-78 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HW35_16530 c7b2449f8817ed3c736af8e8dda59a2f 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 5.5E-73 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 HW35_16530 c7b2449f8817ed3c736af8e8dda59a2f 204 Gene3D G3DSA:3.40.50.300 9 183 4.6E-68 T 12-10-2018 HW35_16530 c7b2449f8817ed3c736af8e8dda59a2f 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 HW35_16530 c7b2449f8817ed3c736af8e8dda59a2f 204 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 37.12 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 HW35_16530 c7b2449f8817ed3c736af8e8dda59a2f 204 SUPERFAMILY SSF52540 3 193 5.64E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16530 c7b2449f8817ed3c736af8e8dda59a2f 204 Pfam PF00625 Guanylate kinase 7 185 9.3E-54 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HW35_16530 c7b2449f8817ed3c736af8e8dda59a2f 204 Gene3D G3DSA:3.30.63.10 37 96 4.6E-68 T 12-10-2018 HW35_10665 3939cd9c678e588cc302ba9cf193b7db 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 49 3.2E-22 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10665 3939cd9c678e588cc302ba9cf193b7db 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 121 4.1E-54 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10665 3939cd9c678e588cc302ba9cf193b7db 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 8.2E-33 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10665 3939cd9c678e588cc302ba9cf193b7db 121 SUPERFAMILY SSF54736 50 121 1.6E-26 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HW35_10665 3939cd9c678e588cc302ba9cf193b7db 121 Gene3D G3DSA:3.30.1390.10 52 121 3.5E-33 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HW35_10665 3939cd9c678e588cc302ba9cf193b7db 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 121 4.0E-17 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10665 3939cd9c678e588cc302ba9cf193b7db 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 121 26.077 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10665 3939cd9c678e588cc302ba9cf193b7db 121 SUPERFAMILY SSF48300 1 57 2.35E-19 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10665 3939cd9c678e588cc302ba9cf193b7db 121 Gene3D G3DSA:1.20.5.710 1 51 5.0E-23 T 12-10-2018 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 17 520 2.6E-205 T 12-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 468 5.7E-144 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 SUPERFAMILY SSF81442 13 522 7.06E-176 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 244 298 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 425 446 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 63 86 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 347 365 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 180 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 242 263 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 132 144 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 303 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 312 333 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 16 41 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 90 114 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 375 394 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 191 210 8.1E-104 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16100 bc670018dd4e44de9e823c5f8317fbdf 622 Gene3D G3DSA:1.20.210.10 2 529 3.7E-201 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 SUPERFAMILY SSF46894 154 225 7.14E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 Pfam PF00072 Response regulator receiver domain 5 117 7.4E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 SMART SM00448 3 116 8.9E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 Gene3D G3DSA:3.40.50.12740 3 224 7.1E-74 T 12-10-2018 HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 218 9.8E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 SUPERFAMILY SSF52172 2 135 1.57E-37 T 12-10-2018 IPR011006 CheY-like superfamily HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 SMART SM00421 161 218 2.5E-28 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 9.2E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 9.2E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_07900 e7fb622e0e8221409b0921e84e3735fe 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 9.2E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_16970 7c8dab0c78d9ae15d7fb0cdc2f958991 261 Gene3D G3DSA:3.30.70.260 10 75 5.9E-5 T 12-10-2018 HW35_16970 7c8dab0c78d9ae15d7fb0cdc2f958991 261 Pfam PF11868 Protein of unknown function (DUF3388) 71 260 6.3E-108 T 12-10-2018 IPR024514 Domain of unknown function DUF3388 HW35_16970 7c8dab0c78d9ae15d7fb0cdc2f958991 261 PIRSF PIRSF021288 1 261 2.4E-146 T 12-10-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain HW35_16970 7c8dab0c78d9ae15d7fb0cdc2f958991 261 SUPERFAMILY SSF55021 5 72 1.3E-8 T 12-10-2018 HW35_07930 59a2a059d2f4af717b54aa02a482c50e 311 Gene3D G3DSA:3.90.550.10 1 232 4.0E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_07930 59a2a059d2f4af717b54aa02a482c50e 311 SUPERFAMILY SSF53448 2 255 1.33E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_07930 59a2a059d2f4af717b54aa02a482c50e 311 Pfam PF00535 Glycosyl transferase family 2 5 154 7.8E-19 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HW35_05360 dc245015f7af928d3d6b4cc909846ef8 350 Pfam PF10646 Sporulation and spore germination 66 176 7.0E-21 T 12-10-2018 IPR019606 GerMN domain HW35_05360 dc245015f7af928d3d6b4cc909846ef8 350 Pfam PF10646 Sporulation and spore germination 213 324 6.8E-17 T 12-10-2018 IPR019606 GerMN domain HW35_05360 dc245015f7af928d3d6b4cc909846ef8 350 SMART SM00909 89 180 5.2E-22 T 12-10-2018 IPR019606 GerMN domain HW35_05360 dc245015f7af928d3d6b4cc909846ef8 350 SMART SM00909 241 330 2.1E-20 T 12-10-2018 IPR019606 GerMN domain HW35_02975 5ecd304b4367b9b71b4014177eb67571 306 SUPERFAMILY SSF103481 41 141 1.31E-11 T 12-10-2018 HW35_02975 5ecd304b4367b9b71b4014177eb67571 306 Pfam PF00892 EamA-like transporter family 150 287 3.6E-18 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_02975 5ecd304b4367b9b71b4014177eb67571 306 Pfam PF00892 EamA-like transporter family 7 140 1.3E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_02975 5ecd304b4367b9b71b4014177eb67571 306 SUPERFAMILY SSF103481 213 292 4.32E-13 T 12-10-2018 HW35_12230 a20b67f12326ae72f3ce2cbb58d77b63 309 Pfam PF01497 Periplasmic binding protein 60 281 5.7E-31 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain HW35_12230 a20b67f12326ae72f3ce2cbb58d77b63 309 SUPERFAMILY SSF53807 40 302 2.67E-48 T 12-10-2018 HW35_12230 a20b67f12326ae72f3ce2cbb58d77b63 309 Gene3D G3DSA:3.40.50.1980 51 139 3.3E-25 T 12-10-2018 HW35_12230 a20b67f12326ae72f3ce2cbb58d77b63 309 Gene3D G3DSA:3.40.50.1980 140 308 2.3E-56 T 12-10-2018 HW35_12430 05404d8b1ece82c605c3cfb30143b966 339 Gene3D G3DSA:3.40.50.720 1 250 4.4E-73 T 12-10-2018 HW35_12430 05404d8b1ece82c605c3cfb30143b966 339 SUPERFAMILY SSF69572 3 330 2.09E-83 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 HW35_12430 05404d8b1ece82c605c3cfb30143b966 339 Pfam PF00899 ThiF family 5 241 1.5E-58 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HW35_14010 f15d7a458a842c664be410ac8c2095fc 287 Pfam PF05107 CRISPR-associated protein Cas7 7 273 3.2E-84 T 12-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C HW35_14010 f15d7a458a842c664be410ac8c2095fc 287 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 4 271 2.0E-76 T 12-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C HW35_14010 f15d7a458a842c664be410ac8c2095fc 287 TIGRFAM TIGR02589 cas_Csd2: CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG 7 274 5.9E-108 T 12-10-2018 IPR013418 CRISPR-associated protein Csd2 HW35_13340 a7839bed37caef3e07e943ce972377af 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 215 1.6E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_13340 a7839bed37caef3e07e943ce972377af 218 SUPERFAMILY SSF161098 13 201 5.63E-51 T 12-10-2018 IPR035906 MetI-like superfamily HW35_13340 a7839bed37caef3e07e943ce972377af 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 1.2E-25 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 HW35_13340 a7839bed37caef3e07e943ce972377af 218 Gene3D G3DSA:1.10.3720.10 1 217 1.3E-63 T 12-10-2018 IPR035906 MetI-like superfamily HW35_08025 d194aa6a7891c59f488e881cf093e6c4 228 Gene3D G3DSA:3.90.550.10 1 228 3.9E-59 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_08025 d194aa6a7891c59f488e881cf093e6c4 228 SUPERFAMILY SSF53448 1 225 6.98E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_08025 d194aa6a7891c59f488e881cf093e6c4 228 Pfam PF12804 MobA-like NTP transferase domain 3 78 1.1E-12 T 12-10-2018 IPR025877 MobA-like NTP transferase HW35_08025 d194aa6a7891c59f488e881cf093e6c4 228 PIRSF PIRSF037382 1 228 3.2E-96 T 12-10-2018 IPR017189 CTP:phosphocholine cytidylyltransferase HW35_17620 df90590114a33ae4a9d808bba5dc51e6 1046 Gene3D G3DSA:1.20.1640.10 840 1040 1.0E-6 T 12-10-2018 HW35_17620 df90590114a33ae4a9d808bba5dc51e6 1046 Gene3D G3DSA:1.20.1640.10 149 343 7.5E-12 T 12-10-2018 HW35_17620 df90590114a33ae4a9d808bba5dc51e6 1046 Gene3D G3DSA:1.10.287.950 489 621 4.2E-6 T 12-10-2018 HW35_17620 df90590114a33ae4a9d808bba5dc51e6 1046 SUPERFAMILY SSF58104 489 606 1.83E-5 T 12-10-2018 HW35_17620 df90590114a33ae4a9d808bba5dc51e6 1046 Pfam PF03176 MMPL family 43 366 9.0E-63 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 HW35_17620 df90590114a33ae4a9d808bba5dc51e6 1046 Pfam PF03176 MMPL family 752 1044 6.0E-49 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 HW35_17620 df90590114a33ae4a9d808bba5dc51e6 1046 SUPERFAMILY SSF82866 836 1043 2.75E-30 T 12-10-2018 HW35_17620 df90590114a33ae4a9d808bba5dc51e6 1046 SUPERFAMILY SSF82866 135 337 7.46E-31 T 12-10-2018 HW35_03500 44131056b5a6f696aedb420259c3bbde 151 ProDom PD089241 YPBF MEMBRANE BH1610 TRANSMEMBRANE 16 149 1.0E-14 T 12-10-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane HW35_03500 44131056b5a6f696aedb420259c3bbde 151 Pfam PF10864 Protein of unknown function (DUF2663) 18 149 1.3E-39 T 12-10-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane HW35_01545 b6b78fda0e65f86a18b2128ca5f3bd7e 121 Gene3D G3DSA:1.10.10.10 10 116 4.5E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_01545 b6b78fda0e65f86a18b2128ca5f3bd7e 121 Pfam PF03551 Transcriptional regulator PadR-like family 23 93 3.0E-22 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal HW35_01545 b6b78fda0e65f86a18b2128ca5f3bd7e 121 SUPERFAMILY SSF46785 20 107 9.47E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_12655 1030799f733e721c8e7ad8b50b8ae34b 388 Pfam PF07690 Major Facilitator Superfamily 18 342 1.4E-25 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_12655 1030799f733e721c8e7ad8b50b8ae34b 388 Gene3D G3DSA:1.20.1250.20 1 190 4.5E-13 T 12-10-2018 HW35_12655 1030799f733e721c8e7ad8b50b8ae34b 388 SUPERFAMILY SSF103473 4 381 2.75E-43 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_12655 1030799f733e721c8e7ad8b50b8ae34b 388 Gene3D G3DSA:1.20.1250.20 193 383 9.3E-19 T 12-10-2018 HW35_04310 d6ba10d485bb21cb8fca4cfbad00ccac 321 Pfam PF12849 PBP superfamily domain 39 291 2.1E-37 T 12-10-2018 IPR024370 PBP domain HW35_04310 d6ba10d485bb21cb8fca4cfbad00ccac 321 Gene3D G3DSA:3.40.190.10 126 266 5.3E-90 T 12-10-2018 HW35_04310 d6ba10d485bb21cb8fca4cfbad00ccac 321 SUPERFAMILY SSF53850 45 318 8.69E-77 T 12-10-2018 HW35_04310 d6ba10d485bb21cb8fca4cfbad00ccac 321 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 5 305 2.2E-93 T 12-10-2018 IPR011862 Phosphate binding protein GO:0042301 HW35_04310 d6ba10d485bb21cb8fca4cfbad00ccac 321 Gene3D G3DSA:3.40.190.10 47 303 5.3E-90 T 12-10-2018 HW35_01145 adc3807fe6d2fa2d6a8bdbe09d70cd44 488 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 12 486 2.9E-191 T 12-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 HW35_01145 adc3807fe6d2fa2d6a8bdbe09d70cd44 488 Gene3D G3DSA:3.40.605.10 26 463 8.8E-153 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_01145 adc3807fe6d2fa2d6a8bdbe09d70cd44 488 Gene3D G3DSA:3.40.309.10 256 455 8.8E-153 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 HW35_01145 adc3807fe6d2fa2d6a8bdbe09d70cd44 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 HW35_01145 adc3807fe6d2fa2d6a8bdbe09d70cd44 488 SUPERFAMILY SSF53720 6 485 9.95E-152 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HW35_01145 adc3807fe6d2fa2d6a8bdbe09d70cd44 488 Pfam PF00171 Aldehyde dehydrogenase family 19 481 1.8E-148 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 HW35_01145 adc3807fe6d2fa2d6a8bdbe09d70cd44 488 Hamap MF_01670 Malonate-semialdehyde dehydrogenase [iolA]. 5 486 70.982 T 12-10-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642 HW35_16090 0bff1d7760f1330d3e73887f0885c521 308 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 84 106 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site HW35_16090 0bff1d7760f1330d3e73887f0885c521 308 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 26 305 2.3E-91 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 HW35_16090 0bff1d7760f1330d3e73887f0885c521 308 Gene3D G3DSA:1.10.357.140 32 189 1.8E-15 T 12-10-2018 HW35_16090 0bff1d7760f1330d3e73887f0885c521 308 Pfam PF01040 UbiA prenyltransferase family 41 291 3.7E-56 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 HW35_16090 0bff1d7760f1330d3e73887f0885c521 308 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 24 307 18.121 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 HW35_01580 b926f2d67991b1edf323234e4abf06cd 371 SUPERFAMILY SSF144052 2 358 1.24E-107 T 12-10-2018 HW35_01580 b926f2d67991b1edf323234e4abf06cd 371 Pfam PF02073 Thermophilic metalloprotease (M29) 3 333 5.4E-59 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 HW35_01580 b926f2d67991b1edf323234e4abf06cd 371 Gene3D G3DSA:3.40.1830.10 2 155 1.2E-15 T 12-10-2018 IPR035097 Peptidase M29, N-terminal HW35_04485 4295cb6939f0db1ffca2a6039857e00f 726 TIGRFAM TIGR00277 HDIG: HDIG domain 509 607 8.6E-28 T 12-10-2018 IPR006675 HDIG domain HW35_04485 4295cb6939f0db1ffca2a6039857e00f 726 Gene3D G3DSA:1.10.3210.10 485 680 5.3E-23 T 12-10-2018 HW35_04485 4295cb6939f0db1ffca2a6039857e00f 726 SMART SM00471 508 665 9.1E-9 T 12-10-2018 IPR003607 HD/PDEase domain HW35_04485 4295cb6939f0db1ffca2a6039857e00f 726 Pfam PF07697 7TM-HD extracellular 50 281 7.7E-40 T 12-10-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain HW35_04485 4295cb6939f0db1ffca2a6039857e00f 726 Pfam PF07698 7TM receptor with intracellular HD hydrolase 287 487 2.3E-45 T 12-10-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain HW35_04485 4295cb6939f0db1ffca2a6039857e00f 726 Pfam PF01966 HD domain 512 655 2.9E-18 T 12-10-2018 IPR006674 HD domain HW35_04485 4295cb6939f0db1ffca2a6039857e00f 726 SUPERFAMILY SSF109604 511 706 5.34E-16 T 12-10-2018 HW35_12585 c35cd8c888b5e83ac87732cf59c904c6 290 SUPERFAMILY SSF53335 20 262 1.57E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_12585 c35cd8c888b5e83ac87732cf59c904c6 290 Gene3D G3DSA:3.40.50.150 17 290 2.9E-57 T 12-10-2018 HW35_12585 c35cd8c888b5e83ac87732cf59c904c6 290 PIRSF PIRSF018249 6 290 1.5E-77 T 12-10-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 HW35_12585 c35cd8c888b5e83ac87732cf59c904c6 290 Pfam PF13649 Methyltransferase domain 104 188 6.1E-7 T 12-10-2018 HW35_13240 2f6ac798ac93dde5b3da36247b2cdf92 423 PIRSF PIRSF006304 4 422 3.4E-164 T 12-10-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 HW35_13240 2f6ac798ac93dde5b3da36247b2cdf92 423 TIGRFAM TIGR00827 EIIC-GAT: PTS system, galactitol-specific IIC component 11 414 2.0E-169 T 12-10-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 HW35_13240 2f6ac798ac93dde5b3da36247b2cdf92 423 Pfam PF03611 PTS system sugar-specific permease component 11 392 1.4E-91 T 12-10-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 Gene3D G3DSA:1.10.490.10 1 145 6.1E-59 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 Gene3D G3DSA:3.40.50.80 263 401 2.0E-34 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 PRINTS PR00410 Phenol hydroxylase reductase family signature 364 372 2.6E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 PRINTS PR00410 Phenol hydroxylase reductase family signature 270 289 2.6E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 PRINTS PR00410 Phenol hydroxylase reductase family signature 185 197 2.6E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 SUPERFAMILY SSF46458 2 143 8.65E-44 T 12-10-2018 IPR009050 Globin-like superfamily HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 Pfam PF00042 Globin 8 103 2.2E-12 T 12-10-2018 IPR000971 Globin GO:0020037 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 Hamap MF_01252 Flavohemoprotein [hmp]. 1 402 59.6 T 12-10-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 Pfam PF00970 Oxidoreductase FAD-binding domain 159 259 1.5E-10 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 185 195 3.5E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 234 243 3.5E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 270 289 3.5E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 206 213 3.5E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 SUPERFAMILY SSF63380 151 261 7.66E-33 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 SUPERFAMILY SSF52343 262 398 4.58E-37 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 Pfam PF00175 Oxidoreductase NAD-binding domain 271 377 8.1E-19 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 HW35_17655 05364f5fe844fc29c416ecf685aa2754 403 Gene3D G3DSA:2.40.30.10 151 260 3.8E-40 T 12-10-2018 HW35_05075 ac5ce01ee3fbcdede2ec2bb42858c9f9 226 Gene3D G3DSA:2.160.20.70 99 224 1.4E-37 T 12-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 HW35_05075 ac5ce01ee3fbcdede2ec2bb42858c9f9 226 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 7 209 2.3E-35 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 HW35_05075 ac5ce01ee3fbcdede2ec2bb42858c9f9 226 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 106 206 2.4E-31 T 12-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 HW35_05075 ac5ce01ee3fbcdede2ec2bb42858c9f9 226 SUPERFAMILY SSF63848 104 205 4.58E-30 T 12-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 HW35_05075 ac5ce01ee3fbcdede2ec2bb42858c9f9 226 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 6 210 21.847 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 HW35_05075 ac5ce01ee3fbcdede2ec2bb42858c9f9 226 Gene3D G3DSA:3.30.160.540 5 85 8.1E-29 T 12-10-2018 HW35_04750 a2c04b00315c15b2bc20e4e0a39c817a 216 Pfam PF01596 O-methyltransferase 26 211 5.6E-36 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 HW35_04750 a2c04b00315c15b2bc20e4e0a39c817a 216 Gene3D G3DSA:3.40.50.150 1 214 1.4E-65 T 12-10-2018 HW35_04750 a2c04b00315c15b2bc20e4e0a39c817a 216 SUPERFAMILY SSF53335 21 213 7.54E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_09855 66daf68b564a5bdd2289788f4b7fb670 657 Pfam PF02272 DHHA1 domain 518 647 9.4E-15 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HW35_09855 66daf68b564a5bdd2289788f4b7fb670 657 Gene3D G3DSA:3.90.1640.10 322 540 3.4E-53 T 12-10-2018 HW35_09855 66daf68b564a5bdd2289788f4b7fb670 657 Gene3D G3DSA:3.10.310.30 543 655 8.2E-9 T 12-10-2018 HW35_09855 66daf68b564a5bdd2289788f4b7fb670 657 PIRSF PIRSF026583 1 657 7.1E-267 T 12-10-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA HW35_09855 66daf68b564a5bdd2289788f4b7fb670 657 SUPERFAMILY SSF64182 338 639 3.27E-68 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily HW35_09855 66daf68b564a5bdd2289788f4b7fb670 657 SMART SM00267 132 299 1.2E-5 T 12-10-2018 IPR000160 GGDEF domain HW35_09855 66daf68b564a5bdd2289788f4b7fb670 657 Pfam PF01368 DHH family 339 496 5.0E-22 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HW35_09855 66daf68b564a5bdd2289788f4b7fb670 657 Gene3D G3DSA:3.30.450.20 52 161 3.4E-35 T 12-10-2018 HW35_01305 9a02be8f5ac989609d7342bc98572eda 268 Gene3D G3DSA:1.10.10.2520 149 231 4.2E-28 T 12-10-2018 HW35_01305 9a02be8f5ac989609d7342bc98572eda 268 Pfam PF07486 Cell Wall Hydrolase 165 266 3.4E-26 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 HW35_01305 9a02be8f5ac989609d7342bc98572eda 268 Gene3D G3DSA:2.40.10.420 233 268 1.9E-15 T 12-10-2018 HW35_09060 a869dbf19ef0faf61dc58dbc68234d5c 366 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 3 366 46.811 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09060 a869dbf19ef0faf61dc58dbc68234d5c 366 SUPERFAMILY SSF56762 16 365 1.18E-121 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09060 a869dbf19ef0faf61dc58dbc68234d5c 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 365 4.4E-92 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09060 a869dbf19ef0faf61dc58dbc68234d5c 366 Gene3D G3DSA:1.10.645.20 4 366 1.4E-154 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 SUPERFAMILY SSF46785 3 70 3.19E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 161 173 3.8E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 132 143 3.8E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 121 131 3.8E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 Gene3D G3DSA:2.10.109.10 89 206 2.7E-43 T 12-10-2018 HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 Pfam PF00717 Peptidase S24-like 124 190 3.3E-18 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 Pfam PF01726 LexA DNA binding domain 1 65 4.4E-28 T 12-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 Gene3D G3DSA:1.10.10.10 2 68 1.5E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 TIGRFAM TIGR00498 lexA: repressor LexA 1 206 6.7E-80 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 Hamap MF_00015 LexA repressor [lexA]. 3 206 34.892 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 HW35_17180 e4494e6765c58ca1ccfea0e45b1024a6 207 SUPERFAMILY SSF51306 83 204 1.74E-35 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily HW35_01680 fef823cb4a13a4cbf4d843486bda6e9e 476 Pfam PF03553 Na+/H+ antiporter family 155 472 1.1E-33 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 HW35_03115 26d1cd74c858ca265c5785b4d2ad55f4 158 SUPERFAMILY SSF49764 39 151 7.32E-25 T 12-10-2018 IPR008978 HSP20-like chaperone HW35_03115 26d1cd74c858ca265c5785b4d2ad55f4 158 Pfam PF00011 Hsp20/alpha crystallin family 59 151 7.8E-16 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain HW35_03115 26d1cd74c858ca265c5785b4d2ad55f4 158 Gene3D G3DSA:2.60.40.790 9 157 5.4E-27 T 12-10-2018 IPR008978 HSP20-like chaperone HW35_04210 d879eda793ead76f898989a472fe6768 232 Gene3D G3DSA:1.10.10.10 1 90 4.0E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_04210 d879eda793ead76f898989a472fe6768 232 SMART SM00418 6 88 0.0029 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_04210 d879eda793ead76f898989a472fe6768 232 SUPERFAMILY SSF46785 1 203 7.34E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_04210 d879eda793ead76f898989a472fe6768 232 Pfam PF12840 Helix-turn-helix domain 7 60 4.5E-7 T 12-10-2018 HW35_02365 4c626ad8c590972818ef396e08bb0cd4 203 Gene3D G3DSA:3.90.79.10 1 200 6.9E-48 T 12-10-2018 HW35_02365 4c626ad8c590972818ef396e08bb0cd4 203 Pfam PF00293 NUDIX domain 25 133 2.4E-12 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HW35_02365 4c626ad8c590972818ef396e08bb0cd4 203 SUPERFAMILY SSF55811 23 194 6.16E-28 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 HW35_16580 3cb4244174a8120a220d5a0d26277117 293 SUPERFAMILY SSF50249 1 63 1.76E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_16580 3cb4244174a8120a220d5a0d26277117 293 Gene3D G3DSA:1.10.40.50 226 293 6.8E-23 T 12-10-2018 HW35_16580 3cb4244174a8120a220d5a0d26277117 293 Pfam PF03193 RsgA GTPase 59 225 1.3E-63 T 12-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 HW35_16580 3cb4244174a8120a220d5a0d26277117 293 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 2 290 39.541 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 HW35_16580 3cb4244174a8120a220d5a0d26277117 293 Gene3D G3DSA:3.40.50.300 62 225 4.1E-48 T 12-10-2018 HW35_16580 3cb4244174a8120a220d5a0d26277117 293 Gene3D G3DSA:2.40.50.140 1 61 1.7E-27 T 12-10-2018 HW35_16580 3cb4244174a8120a220d5a0d26277117 293 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 283 5.8E-91 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 HW35_16580 3cb4244174a8120a220d5a0d26277117 293 Pfam PF16745 RsgA N-terminal domain 3 56 1.4E-25 T 12-10-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal HW35_16580 3cb4244174a8120a220d5a0d26277117 293 SUPERFAMILY SSF52540 64 290 2.22E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07640 889e80428d1fa01b868d38d79eeac303 242 Pfam PF00977 Histidine biosynthesis protein 5 232 6.9E-76 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 HW35_07640 889e80428d1fa01b868d38d79eeac303 242 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 239 36.416 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 HW35_07640 889e80428d1fa01b868d38d79eeac303 242 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 5 235 1.6E-81 T 12-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 HW35_07640 889e80428d1fa01b868d38d79eeac303 242 SUPERFAMILY SSF51366 4 239 1.02E-69 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HW35_07640 889e80428d1fa01b868d38d79eeac303 242 Gene3D G3DSA:3.20.20.70 1 241 4.0E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_03165 9e07edca275fe5097d44c279d2183974 200 TIGRFAM TIGR00648 recU: recombination protein U 30 198 2.3E-81 T 12-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 HW35_03165 9e07edca275fe5097d44c279d2183974 200 Gene3D G3DSA:3.40.1350.10 34 200 2.2E-70 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 HW35_03165 9e07edca275fe5097d44c279d2183974 200 Pfam PF03838 Recombination protein U 31 196 1.5E-70 T 12-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 HW35_03165 9e07edca275fe5097d44c279d2183974 200 PIRSF PIRSF037785 23 200 1.2E-78 T 12-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 HW35_03165 9e07edca275fe5097d44c279d2183974 200 SUPERFAMILY SSF52980 33 199 1.66E-71 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 HW35_03165 9e07edca275fe5097d44c279d2183974 200 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 200 101.036 T 12-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 HW35_13380 6908f1dd76815b33a5e89e3a7bbde942 372 Pfam PF08756 YfkB-like domain 218 368 5.5E-78 T 12-10-2018 IPR014866 YfkB-like domain HW35_13380 6908f1dd76815b33a5e89e3a7bbde942 372 Pfam PF04055 Radical SAM superfamily 34 182 3.3E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_13380 6908f1dd76815b33a5e89e3a7bbde942 372 Pfam PF13353 4Fe-4S single cluster domain 38 110 5.7E-5 T 12-10-2018 HW35_13380 6908f1dd76815b33a5e89e3a7bbde942 372 SUPERFAMILY SSF102114 30 326 2.88E-24 T 12-10-2018 HW35_13380 6908f1dd76815b33a5e89e3a7bbde942 372 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 6 368 3.1E-193 T 12-10-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB HW35_13380 6908f1dd76815b33a5e89e3a7bbde942 372 Gene3D G3DSA:3.20.20.70 20 295 1.7E-20 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_11125 35feb35e38a65447f35e9de3634409d0 277 Gene3D G3DSA:3.30.420.10 109 267 5.7E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_11125 35feb35e38a65447f35e9de3634409d0 277 SUPERFAMILY SSF53098 119 269 6.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_11125 35feb35e38a65447f35e9de3634409d0 277 Pfam PF00665 Integrase core domain 118 228 1.7E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_11125 35feb35e38a65447f35e9de3634409d0 277 Pfam PF13276 HTH-like domain 35 87 1.0E-11 T 12-10-2018 IPR025948 HTH-like domain HW35_07885 924549841b1172f4c910b1aaef68c694 238 Pfam PF00156 Phosphoribosyl transferase domain 183 236 1.4E-8 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HW35_07885 924549841b1172f4c910b1aaef68c694 238 SUPERFAMILY SSF53271 80 236 2.23E-22 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_07885 924549841b1172f4c910b1aaef68c694 238 Gene3D G3DSA:3.40.50.2020 85 238 1.2E-16 T 12-10-2018 HW35_10685 e77b8a6abde3d661e1bed6d179e98bd1 82 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 80 9.5E-14 T 12-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 HW35_10685 e77b8a6abde3d661e1bed6d179e98bd1 82 Hamap MF_00574 Putative ribosomal protein L7Ae-like. 2 82 23.554 T 12-10-2018 IPR023460 Ribosomal protein L7Ae, putative HW35_10685 e77b8a6abde3d661e1bed6d179e98bd1 82 SUPERFAMILY SSF55315 4 81 7.51E-20 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like HW35_10685 e77b8a6abde3d661e1bed6d179e98bd1 82 Gene3D G3DSA:3.30.1330.30 1 81 2.0E-23 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like HW35_10685 e77b8a6abde3d661e1bed6d179e98bd1 82 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 9 33 - T 12-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_12755 c7b082971b1430922166fa03fbb509a8 537 Gene3D G3DSA:3.40.50.980 182 354 1.4E-57 T 12-10-2018 HW35_12755 c7b082971b1430922166fa03fbb509a8 537 Pfam PF00501 AMP-binding enzyme 31 436 2.8E-87 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_12755 c7b082971b1430922166fa03fbb509a8 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 519 4.8E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_12755 c7b082971b1430922166fa03fbb509a8 537 Gene3D G3DSA:2.30.38.10 355 430 4.3E-31 T 12-10-2018 HW35_12755 c7b082971b1430922166fa03fbb509a8 537 Gene3D G3DSA:3.30.300.310 432 533 1.1E-28 T 12-10-2018 HW35_12755 c7b082971b1430922166fa03fbb509a8 537 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 4 526 2.2E-231 T 12-10-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 HW35_12755 c7b082971b1430922166fa03fbb509a8 537 Gene3D G3DSA:3.40.50.980 22 179 6.3E-50 T 12-10-2018 HW35_12755 c7b082971b1430922166fa03fbb509a8 537 SUPERFAMILY SSF56801 8 531 4.45E-137 T 12-10-2018 HW35_12755 c7b082971b1430922166fa03fbb509a8 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_05810 d39a645e323ad7e89e65344ac805441f 160 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 139 2.4E-55 T 12-10-2018 IPR014229 Sporulation protein YtfJ HW35_05810 d39a645e323ad7e89e65344ac805441f 160 PIRSF PIRSF021377 1 157 1.8E-62 T 12-10-2018 IPR014229 Sporulation protein YtfJ HW35_05810 d39a645e323ad7e89e65344ac805441f 160 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 130 2.3E-28 T 12-10-2018 IPR014229 Sporulation protein YtfJ HW35_10755 f77a6762d8777e2fe8c7dc4cc8cbcfa6 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 19.203 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10755 f77a6762d8777e2fe8c7dc4cc8cbcfa6 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 5.7E-25 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10755 f77a6762d8777e2fe8c7dc4cc8cbcfa6 66 SUPERFAMILY SSF46561 1 63 3.01E-24 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10755 f77a6762d8777e2fe8c7dc4cc8cbcfa6 66 Gene3D G3DSA:1.10.287.310 1 66 4.5E-31 T 12-10-2018 HW35_10755 f77a6762d8777e2fe8c7dc4cc8cbcfa6 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 12-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10755 f77a6762d8777e2fe8c7dc4cc8cbcfa6 66 Pfam PF00831 Ribosomal L29 protein 4 60 1.3E-26 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_13315 5d5be1a0691839c6354b0fb1411dea03 303 Pfam PF01063 Amino-transferase class IV 33 257 1.7E-59 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 HW35_13315 5d5be1a0691839c6354b0fb1411dea03 303 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 8 288 5.0E-106 T 12-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 HW35_13315 5d5be1a0691839c6354b0fb1411dea03 303 Gene3D G3DSA:3.30.470.10 4 125 1.7E-47 T 12-10-2018 HW35_13315 5d5be1a0691839c6354b0fb1411dea03 303 Gene3D G3DSA:3.20.10.10 126 297 5.6E-55 T 12-10-2018 HW35_13315 5d5be1a0691839c6354b0fb1411dea03 303 SUPERFAMILY SSF56752 6 288 3.14E-93 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 HW35_13315 5d5be1a0691839c6354b0fb1411dea03 303 ProSitePatterns PS00770 Aminotransferases class-IV signature. 186 215 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.3E-53 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.7E-63 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 Gene3D G3DSA:3.90.1170.10 1 143 1.3E-56 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 SUPERFAMILY SSF54686 1 137 2.49E-60 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 2.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 2.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 2.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 2.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10750 1f800f1b1a9f18d8775e1ccc7f2ec554 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.333 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09145 bcb93c94d28ceabb5cd7f591b942c611 413 SUPERFAMILY SSF53383 3 411 8.7E-186 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_09145 bcb93c94d28ceabb5cd7f591b942c611 413 PIRSF PIRSF000412 1 411 2.8E-176 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HW35_09145 bcb93c94d28ceabb5cd7f591b942c611 413 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 54.354 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HW35_09145 bcb93c94d28ceabb5cd7f591b942c611 413 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 12-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HW35_09145 bcb93c94d28ceabb5cd7f591b942c611 413 Gene3D G3DSA:3.40.640.10 33 283 2.0E-191 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_09145 bcb93c94d28ceabb5cd7f591b942c611 413 Gene3D G3DSA:3.90.1150.10 6 388 2.0E-191 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_09145 bcb93c94d28ceabb5cd7f591b942c611 413 Pfam PF00464 Serine hydroxymethyltransferase 4 380 1.9E-182 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HW35_10230 8677b5a3b10de8126440f18e331f4385 87 PIRSF PIRSF037257 1 85 1.7E-36 T 12-10-2018 IPR009366 Protein Veg GO:0006355 HW35_10230 8677b5a3b10de8126440f18e331f4385 87 Pfam PF06257 Biofilm formation stimulator VEG 4 74 4.9E-31 T 12-10-2018 IPR009366 Protein Veg GO:0006355 HW35_10230 8677b5a3b10de8126440f18e331f4385 87 Gene3D G3DSA:2.30.30.100 1 78 4.5E-26 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 Gene3D G3DSA:3.40.50.300 67 291 3.7E-40 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 PRINTS PR01874 DNA repair protein radA signature 175 199 2.5E-93 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 PRINTS PR01874 DNA repair protein radA signature 249 275 2.5E-93 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 PRINTS PR01874 DNA repair protein radA signature 10 34 2.5E-93 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 PRINTS PR01874 DNA repair protein radA signature 214 242 2.5E-93 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 PRINTS PR01874 DNA repair protein radA signature 323 346 2.5E-93 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 PRINTS PR01874 DNA repair protein radA signature 125 142 2.5E-93 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 PRINTS PR01874 DNA repair protein radA signature 83 111 2.5E-93 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 SUPERFAMILY SSF54211 256 458 1.74E-42 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_10585 27418a21c813be78bf8b39dff779128e 459 Pfam PF13481 AAA domain 75 223 1.8E-16 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 Gene3D G3DSA:3.30.230.10 324 458 1.6E-19 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_10585 27418a21c813be78bf8b39dff779128e 459 SUPERFAMILY SSF52540 72 291 6.55E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10585 27418a21c813be78bf8b39dff779128e 459 Hamap MF_01498 DNA repair protein RadA [radA]. 21 457 44.784 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 HW35_10585 27418a21c813be78bf8b39dff779128e 459 Pfam PF13541 Subunit ChlI of Mg-chelatase 367 431 5.1E-10 T 12-10-2018 HW35_10585 27418a21c813be78bf8b39dff779128e 459 SMART SM00382 91 245 1.2E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_10585 27418a21c813be78bf8b39dff779128e 459 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 453 7.5E-215 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 HW35_15055 cc952ae0ebb2572e88f3cd6453351eb8 221 Pfam PF09335 SNARE associated Golgi protein 43 161 2.3E-22 T 12-10-2018 IPR032816 SNARE associated Golgi protein HW35_05375 26d637f627625775e88afdf12b4f6920 419 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 1.7E-47 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_05375 26d637f627625775e88afdf12b4f6920 419 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 1.5E-133 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_05375 26d637f627625775e88afdf12b4f6920 419 Pfam PF08388 Group II intron, maturase-specific domain 288 360 6.7E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_05375 26d637f627625775e88afdf12b4f6920 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05375 26d637f627625775e88afdf12b4f6920 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05375 26d637f627625775e88afdf12b4f6920 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05375 26d637f627625775e88afdf12b4f6920 419 SUPERFAMILY SSF56672 16 356 5.56E-62 T 12-10-2018 HW35_06140 45570f68801a1c82ddb06dece61336d1 190 Pfam PF06962 Putative rRNA methylase 48 188 7.4E-53 T 12-10-2018 IPR010719 Putative rRNA methylase HW35_06140 45570f68801a1c82ddb06dece61336d1 190 Gene3D G3DSA:3.40.50.150 1 190 1.5E-70 T 12-10-2018 HW35_06140 45570f68801a1c82ddb06dece61336d1 190 SUPERFAMILY SSF53335 18 148 1.05E-19 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_04500 6fac59d94b3bf95408ab7bd6ca07f84b 100 Pfam PF07873 YabP family 28 91 5.2E-18 T 12-10-2018 IPR022476 Sporulation protein YabP/YqfC HW35_04500 6fac59d94b3bf95408ab7bd6ca07f84b 100 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 9 92 6.2E-37 T 12-10-2018 IPR022477 Sporulation protein YqfC HW35_06815 c796a520ddb290b2f72b37b6427627fe 399 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 226 263 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_06815 c796a520ddb290b2f72b37b6427627fe 399 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 7 398 2.0E-169 T 12-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HW35_06815 c796a520ddb290b2f72b37b6427627fe 399 SUPERFAMILY SSF53383 5 398 1.53E-127 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_06815 c796a520ddb290b2f72b37b6427627fe 399 Gene3D G3DSA:3.90.1150.10 26 388 8.2E-154 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_06815 c796a520ddb290b2f72b37b6427627fe 399 Pfam PF00202 Aminotransferase class-III 18 398 9.2E-136 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_06815 c796a520ddb290b2f72b37b6427627fe 399 PIRSF PIRSF000521 178 399 1.0E-32 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_06815 c796a520ddb290b2f72b37b6427627fe 399 PIRSF PIRSF000521 3 163 4.5E-8 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_06815 c796a520ddb290b2f72b37b6427627fe 399 Gene3D G3DSA:3.40.640.10 61 309 8.2E-154 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_06815 c796a520ddb290b2f72b37b6427627fe 399 Hamap MF_01689 Ornithine aminotransferase [rocD]. 7 399 67.618 T 12-10-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 HW35_15905 ea2152e6c895c78f3e987f3124130d42 219 SUPERFAMILY SSF51735 4 134 4.48E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_15905 ea2152e6c895c78f3e987f3124130d42 219 Pfam PF02254 TrkA-N domain 5 120 4.5E-31 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HW35_15905 ea2152e6c895c78f3e987f3124130d42 219 Gene3D G3DSA:3.30.70.1450 138 218 3.5E-28 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_15905 ea2152e6c895c78f3e987f3124130d42 219 Pfam PF02080 TrkA-C domain 150 216 5.5E-16 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HW35_15905 ea2152e6c895c78f3e987f3124130d42 219 SUPERFAMILY SSF116726 131 215 3.66E-21 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_15905 ea2152e6c895c78f3e987f3124130d42 219 Gene3D G3DSA:3.40.50.720 1 137 2.5E-39 T 12-10-2018 HW35_04360 31e66aadc3273e2e12d6adda10e84f9b 284 SUPERFAMILY SSF81345 5 269 8.89E-36 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_04360 31e66aadc3273e2e12d6adda10e84f9b 284 Pfam PF00950 ABC 3 transport family 7 271 1.7E-61 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 HW35_04360 31e66aadc3273e2e12d6adda10e84f9b 284 Gene3D G3DSA:1.10.3470.10 71 275 2.8E-9 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_14105 3c2c02037445647bce808a3961fc0b45 335 SUPERFAMILY SSF161098 89 318 1.96E-20 T 12-10-2018 IPR035906 MetI-like superfamily HW35_14105 3c2c02037445647bce808a3961fc0b45 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 332 7.4E-43 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_10840 c859d7c4b4bf8f48c4eabeacda055a9e 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 1.2E-59 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10840 c859d7c4b4bf8f48c4eabeacda055a9e 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site HW35_10840 c859d7c4b4bf8f48c4eabeacda055a9e 129 SUPERFAMILY SSF53137 14 129 2.16E-50 T 12-10-2018 HW35_10840 c859d7c4b4bf8f48c4eabeacda055a9e 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.639 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HW35_10840 c859d7c4b4bf8f48c4eabeacda055a9e 129 Gene3D G3DSA:3.30.420.80 1 129 3.7E-55 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 HW35_10840 c859d7c4b4bf8f48c4eabeacda055a9e 129 Pfam PF00411 Ribosomal protein S11 19 128 5.6E-53 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HW35_10840 c859d7c4b4bf8f48c4eabeacda055a9e 129 PIRSF PIRSF002131 1 129 2.4E-54 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HW35_14530 c9812a506a237ea2db486e24491faba5 145 SUPERFAMILY SSF49764 9 143 2.09E-35 T 12-10-2018 IPR008978 HSP20-like chaperone HW35_14530 c9812a506a237ea2db486e24491faba5 145 Pfam PF00011 Hsp20/alpha crystallin family 43 143 1.0E-20 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain HW35_14530 c9812a506a237ea2db486e24491faba5 145 Gene3D G3DSA:2.60.40.790 3 143 9.0E-37 T 12-10-2018 IPR008978 HSP20-like chaperone HW35_17625 bba595aceccba27ec4700e6fb7c755b6 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 3.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_17625 bba595aceccba27ec4700e6fb7c755b6 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 3.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_17625 bba595aceccba27ec4700e6fb7c755b6 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 3.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_17625 bba595aceccba27ec4700e6fb7c755b6 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 3.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_17625 bba595aceccba27ec4700e6fb7c755b6 153 Gene3D G3DSA:1.10.10.10 1 150 1.1E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_17625 bba595aceccba27ec4700e6fb7c755b6 153 SMART SM00347 29 129 3.3E-26 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_17625 bba595aceccba27ec4700e6fb7c755b6 153 SUPERFAMILY SSF46785 10 147 7.71E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_17625 bba595aceccba27ec4700e6fb7c755b6 153 Pfam PF01047 MarR family 36 94 4.4E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_13860 8f67f155ccc7abc5fee7591447412128 133 Gene3D G3DSA:3.40.50.10490 1 131 2.5E-17 T 12-10-2018 HW35_13860 8f67f155ccc7abc5fee7591447412128 133 SUPERFAMILY SSF53697 2 129 2.83E-14 T 12-10-2018 HW35_13860 8f67f155ccc7abc5fee7591447412128 133 Pfam PF01380 SIS domain 1 129 2.2E-11 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HW35_12015 729160f712b19fc5f61e27ea0e1617aa 253 Pfam PF00005 ABC transporter 18 164 9.6E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12015 729160f712b19fc5f61e27ea0e1617aa 253 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_12015 729160f712b19fc5f61e27ea0e1617aa 253 SMART SM00382 26 243 6.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_12015 729160f712b19fc5f61e27ea0e1617aa 253 Gene3D G3DSA:3.40.50.300 1 250 1.5E-68 T 12-10-2018 HW35_12015 729160f712b19fc5f61e27ea0e1617aa 253 SUPERFAMILY SSF52540 2 227 2.06E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_08630 6e02b41ed317e58a2e44cd73763b61df 568 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 15 559 1.9E-185 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HW35_08630 6e02b41ed317e58a2e44cd73763b61df 568 Pfam PF02652 L-lactate permease 16 558 2.8E-199 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HW35_03250 dba4a03050fb94d8263ad9445dff2caf 268 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 130 4.5E-33 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03250 dba4a03050fb94d8263ad9445dff2caf 268 SUPERFAMILY SSF55347 131 239 5.01E-39 T 12-10-2018 HW35_03250 dba4a03050fb94d8263ad9445dff2caf 268 Gene3D G3DSA:3.30.360.10 132 237 6.7E-77 T 12-10-2018 HW35_03250 dba4a03050fb94d8263ad9445dff2caf 268 PIRSF PIRSF000161 2 268 4.7E-71 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03250 dba4a03050fb94d8263ad9445dff2caf 268 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 152 169 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03250 dba4a03050fb94d8263ad9445dff2caf 268 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 3 268 7.4E-87 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03250 dba4a03050fb94d8263ad9445dff2caf 268 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 133 267 3.1E-33 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03250 dba4a03050fb94d8263ad9445dff2caf 268 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 268 29.892 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HW35_03250 dba4a03050fb94d8263ad9445dff2caf 268 Gene3D G3DSA:3.40.50.720 5 266 6.7E-77 T 12-10-2018 HW35_03250 dba4a03050fb94d8263ad9445dff2caf 268 SUPERFAMILY SSF51735 3 157 1.44E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_15665 6ac11a3af27a4ab03e3d048be12f924d 764 Gene3D G3DSA:3.40.50.970 535 761 5.1E-40 T 12-10-2018 HW35_15665 6ac11a3af27a4ab03e3d048be12f924d 764 SUPERFAMILY SSF52922 270 403 1.71E-28 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HW35_15665 6ac11a3af27a4ab03e3d048be12f924d 764 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 495 660 4.3E-9 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HW35_15665 6ac11a3af27a4ab03e3d048be12f924d 764 Gene3D G3DSA:3.40.50.970 17 268 4.6E-77 T 12-10-2018 HW35_15665 6ac11a3af27a4ab03e3d048be12f924d 764 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 30 255 2.8E-57 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HW35_15665 6ac11a3af27a4ab03e3d048be12f924d 764 Gene3D G3DSA:3.40.50.920 269 408 9.4E-35 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HW35_15665 6ac11a3af27a4ab03e3d048be12f924d 764 SUPERFAMILY SSF52518 452 762 7.75E-52 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_15665 6ac11a3af27a4ab03e3d048be12f924d 764 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 278 382 6.7E-23 T 12-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HW35_15665 6ac11a3af27a4ab03e3d048be12f924d 764 SUPERFAMILY SSF52518 20 267 2.36E-57 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_01450 4e7b354c16d817114e4e57c027247672 87 Pfam PF02583 Metal-sensitive transcriptional repressor 5 83 4.0E-22 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 HW35_01450 4e7b354c16d817114e4e57c027247672 87 Gene3D G3DSA:1.20.58.1000 2 87 1.4E-20 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily HW35_06630 20abd06a34d213cdf562f7af0cb59058 148 SUPERFAMILY SSF47240 4 145 4.06E-47 T 12-10-2018 IPR009078 Ferritin-like superfamily HW35_06630 20abd06a34d213cdf562f7af0cb59058 148 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 12-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 HW35_06630 20abd06a34d213cdf562f7af0cb59058 148 PIRSF PIRSF005900 1 147 2.0E-48 T 12-10-2018 IPR002177 DNA-binding protein Dps HW35_06630 20abd06a34d213cdf562f7af0cb59058 148 Gene3D G3DSA:1.20.1260.10 2 147 2.1E-53 T 12-10-2018 IPR012347 Ferritin-like HW35_06630 20abd06a34d213cdf562f7af0cb59058 148 Pfam PF00210 Ferritin-like domain 7 146 2.0E-34 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 HW35_06630 20abd06a34d213cdf562f7af0cb59058 148 ProSitePatterns PS00819 Dps protein family signature 2. 53 67 - T 12-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 HW35_06630 20abd06a34d213cdf562f7af0cb59058 148 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 4.4E-15 T 12-10-2018 IPR002177 DNA-binding protein Dps HW35_06630 20abd06a34d213cdf562f7af0cb59058 148 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 4.4E-15 T 12-10-2018 IPR002177 DNA-binding protein Dps HW35_06630 20abd06a34d213cdf562f7af0cb59058 148 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 4.4E-15 T 12-10-2018 IPR002177 DNA-binding protein Dps HW35_10925 3d1e32b1801ad52b4a78fe1f64220e53 399 Gene3D G3DSA:2.40.420.20 310 399 1.9E-19 T 12-10-2018 HW35_10925 3d1e32b1801ad52b4a78fe1f64220e53 399 Gene3D G3DSA:2.40.50.100 76 235 5.0E-16 T 12-10-2018 HW35_10925 3d1e32b1801ad52b4a78fe1f64220e53 399 Gene3D G3DSA:1.10.287.470 103 186 5.0E-16 T 12-10-2018 HW35_10925 3d1e32b1801ad52b4a78fe1f64220e53 399 Pfam PF13533 Biotin-lipoyl like 76 113 6.5E-7 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain HW35_10925 3d1e32b1801ad52b4a78fe1f64220e53 399 Gene3D G3DSA:2.40.30.170 236 280 5.0E-16 T 12-10-2018 HW35_05000 9f130679c825db5b31c6ba996aba0fd9 282 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 19 107 6.2E-24 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 HW35_05000 9f130679c825db5b31c6ba996aba0fd9 282 Gene3D G3DSA:3.20.20.70 123 265 5.6E-102 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_05000 9f130679c825db5b31c6ba996aba0fd9 282 PIRSF PIRSF006250 1 277 4.4E-97 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 HW35_05000 9f130679c825db5b31c6ba996aba0fd9 282 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 274 1.3E-100 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 HW35_05000 9f130679c825db5b31c6ba996aba0fd9 282 SUPERFAMILY SSF51690 109 275 2.32E-59 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 HW35_05000 9f130679c825db5b31c6ba996aba0fd9 282 Gene3D G3DSA:3.90.1170.20 14 272 5.6E-102 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 HW35_05000 9f130679c825db5b31c6ba996aba0fd9 282 SUPERFAMILY SSF54675 2 108 3.77E-27 T 12-10-2018 HW35_05000 9f130679c825db5b31c6ba996aba0fd9 282 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 109 274 1.8E-62 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 HW35_04955 6429a516016be3be9297932a0900ad8d 342 Gene3D G3DSA:3.40.1780.10 14 341 4.8E-137 T 12-10-2018 HW35_04955 6429a516016be3be9297932a0900ad8d 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 47.064 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HW35_04955 6429a516016be3be9297932a0900ad8d 342 Gene3D G3DSA:2.40.10.240 64 162 4.8E-137 T 12-10-2018 HW35_04955 6429a516016be3be9297932a0900ad8d 342 SUPERFAMILY SSF111337 2 342 3.27E-141 T 12-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HW35_04955 6429a516016be3be9297932a0900ad8d 342 Pfam PF02547 Queuosine biosynthesis protein 4 341 8.8E-144 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HW35_04955 6429a516016be3be9297932a0900ad8d 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2 342 7.2E-150 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HW35_00140 cd0c60d08f01b449848416cab5852326 168 Pfam PF12822 ECF transporter, substrate-specific component 8 153 6.4E-10 T 12-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 HW35_00140 cd0c60d08f01b449848416cab5852326 168 Gene3D G3DSA:1.10.1760.20 3 164 7.8E-16 T 12-10-2018 HW35_01185 6e1075ff080ac2f8a49ed97b163d983e 510 Gene3D G3DSA:1.20.1720.10 15 224 3.2E-39 T 12-10-2018 HW35_01185 6e1075ff080ac2f8a49ed97b163d983e 510 Gene3D G3DSA:1.20.1250.20 260 491 4.4E-23 T 12-10-2018 HW35_01185 6e1075ff080ac2f8a49ed97b163d983e 510 Pfam PF07690 Major Facilitator Superfamily 19 410 1.2E-51 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_01185 6e1075ff080ac2f8a49ed97b163d983e 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 1.6E-10 T 12-10-2018 HW35_01185 6e1075ff080ac2f8a49ed97b163d983e 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 1.6E-10 T 12-10-2018 HW35_01185 6e1075ff080ac2f8a49ed97b163d983e 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 303 327 1.6E-10 T 12-10-2018 HW35_01185 6e1075ff080ac2f8a49ed97b163d983e 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 1.6E-10 T 12-10-2018 HW35_01185 6e1075ff080ac2f8a49ed97b163d983e 510 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 482 3.3E-121 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 HW35_01185 6e1075ff080ac2f8a49ed97b163d983e 510 SUPERFAMILY SSF103473 8 489 6.54E-70 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_13690 7891d20bca636769270358bbff989f26 249 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 2.7E-95 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_13690 7891d20bca636769270358bbff989f26 249 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_13690 7891d20bca636769270358bbff989f26 249 Pfam PF00557 Metallopeptidase family M24 11 239 1.8E-57 T 12-10-2018 IPR000994 Peptidase M24 HW35_13690 7891d20bca636769270358bbff989f26 249 Gene3D G3DSA:3.90.230.10 1 249 1.8E-109 T 12-10-2018 HW35_13690 7891d20bca636769270358bbff989f26 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 9.3E-19 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_13690 7891d20bca636769270358bbff989f26 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 9.3E-19 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_13690 7891d20bca636769270358bbff989f26 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 9.3E-19 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_13690 7891d20bca636769270358bbff989f26 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 9.3E-19 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_13690 7891d20bca636769270358bbff989f26 249 SUPERFAMILY SSF55920 1 247 1.07E-90 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like HW35_13690 7891d20bca636769270358bbff989f26 249 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 40.539 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 12-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 Gene3D G3DSA:3.30.70.141 1 148 5.4E-66 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 2.0E-52 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 2.0E-52 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 2.0E-52 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 2.0E-52 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 2.0E-52 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 Pfam PF00334 Nucleoside diphosphate kinase 2 135 5.0E-60 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 SUPERFAMILY SSF54919 1 148 1.31E-63 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 SMART SM00562 1 138 2.0E-97 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HW35_03345 27fb56e43b95cec0e880dd0e70c1ab25 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 38.394 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HW35_06655 f967e74a555cdd1f1c7f468761b49bef 370 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 188 202 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_06655 f967e74a555cdd1f1c7f468761b49bef 370 PIRSF PIRSF001434 1 365 6.6E-123 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_06655 f967e74a555cdd1f1c7f468761b49bef 370 Gene3D G3DSA:3.90.1150.10 279 369 7.8E-27 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_06655 f967e74a555cdd1f1c7f468761b49bef 370 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 361 1.3E-136 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_06655 f967e74a555cdd1f1c7f468761b49bef 370 SUPERFAMILY SSF53383 17 364 1.46E-105 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_06655 f967e74a555cdd1f1c7f468761b49bef 370 Gene3D G3DSA:3.40.640.10 3 245 4.4E-88 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_06655 f967e74a555cdd1f1c7f468761b49bef 370 Gene3D G3DSA:3.90.1150.10 246 278 1.3E-7 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_07485 bd5e5de092eec141660413eed0a49c00 243 Pfam PF00483 Nucleotidyl transferase 2 235 6.7E-57 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HW35_07485 bd5e5de092eec141660413eed0a49c00 243 Gene3D G3DSA:3.90.550.10 1 242 7.0E-73 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_07485 bd5e5de092eec141660413eed0a49c00 243 SUPERFAMILY SSF53448 1 238 6.98E-72 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_12415 308fac80f5600fd77ff953cbcd19e6d5 273 SUPERFAMILY SSF53098 100 263 1.05E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_12415 308fac80f5600fd77ff953cbcd19e6d5 273 Pfam PF13276 HTH-like domain 28 76 9.4E-20 T 12-10-2018 IPR025948 HTH-like domain HW35_12415 308fac80f5600fd77ff953cbcd19e6d5 273 Pfam PF00665 Integrase core domain 109 223 1.2E-23 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_12415 308fac80f5600fd77ff953cbcd19e6d5 273 Gene3D G3DSA:3.30.420.10 99 271 2.7E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_00690 c296f174bce3742176111669979a0d79 223 Gene3D G3DSA:1.20.910.10 1 223 3.3E-67 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 HW35_00690 c296f174bce3742176111669979a0d79 223 SUPERFAMILY SSF48613 1 216 1.47E-71 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 HW35_00690 c296f174bce3742176111669979a0d79 223 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 216 7.8E-59 T 12-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 HW35_00690 c296f174bce3742176111669979a0d79 223 Pfam PF03070 TENA/THI-4/PQQC family 8 217 1.4E-51 T 12-10-2018 IPR004305 Thiaminase-2/PQQC HW35_01915 19a0abea956686d8a4ae94184d49aaba 310 Gene3D G3DSA:3.40.50.720 96 279 2.8E-77 T 12-10-2018 HW35_01915 19a0abea956686d8a4ae94184d49aaba 310 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 275 2.0E-41 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HW35_01915 19a0abea956686d8a4ae94184d49aaba 310 SUPERFAMILY SSF51735 98 275 2.61E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_01915 19a0abea956686d8a4ae94184d49aaba 310 Gene3D G3DSA:3.40.50.720 34 302 2.8E-77 T 12-10-2018 HW35_02400 e2af22ff6dc67d95560c8aa590a1fa8c 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 2.0E-5 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 HW35_02400 e2af22ff6dc67d95560c8aa590a1fa8c 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 14.506 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 HW35_02400 e2af22ff6dc67d95560c8aa590a1fa8c 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 1.7E-13 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 HW35_02400 e2af22ff6dc67d95560c8aa590a1fa8c 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 4.1E-22 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 HW35_12730 89a7e912301ec43ef2846fde88a0f23f 94 Pfam PF02325 YGGT family 12 79 1.7E-18 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 HW35_09880 0ffa4e2b226de5b4fa773557b358f6f4 165 SUPERFAMILY SSF50249 1 165 1.61E-57 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_09880 0ffa4e2b226de5b4fa773557b358f6f4 165 Gene3D G3DSA:2.40.50.140 1 111 7.1E-48 T 12-10-2018 HW35_09880 0ffa4e2b226de5b4fa773557b358f6f4 165 Pfam PF00436 Single-strand binding protein family 2 103 6.7E-39 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 HW35_09880 0ffa4e2b226de5b4fa773557b358f6f4 165 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 37.45 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HW35_09880 0ffa4e2b226de5b4fa773557b358f6f4 165 PIRSF PIRSF002070 1 153 3.0E-43 T 12-10-2018 HW35_09880 0ffa4e2b226de5b4fa773557b358f6f4 165 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 165 2.6E-49 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HW35_09750 3bd890bd5046a25e07e4b8661e46a6cd 182 SUPERFAMILY SSF52218 1 180 1.64E-37 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_09750 3bd890bd5046a25e07e4b8661e46a6cd 182 Gene3D G3DSA:3.40.50.360 1 179 9.2E-52 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_09750 3bd890bd5046a25e07e4b8661e46a6cd 182 Pfam PF03358 NADPH-dependent FMN reductase 1 123 1.4E-20 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HW35_04050 28e917a95934691f3fa9557f23b189a4 103 Pfam PF13798 Protein of unknown function with PCYCGC motif 35 99 2.7E-12 T 12-10-2018 IPR025673 Protein of unknown function with PCYCGC motif HW35_01430 8d52641e4860543ad31192009e15997e 375 SMART SM00450 7 109 4.1E-13 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_01430 8d52641e4860543ad31192009e15997e 375 Pfam PF00753 Metallo-beta-lactamase superfamily 130 292 1.2E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_01430 8d52641e4860543ad31192009e15997e 375 SUPERFAMILY SSF52821 2 110 1.3E-17 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_01430 8d52641e4860543ad31192009e15997e 375 Pfam PF00581 Rhodanese-like domain 7 105 2.9E-9 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_01430 8d52641e4860543ad31192009e15997e 375 SMART SM00849 130 294 1.1E-26 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_01430 8d52641e4860543ad31192009e15997e 375 SUPERFAMILY SSF56281 124 370 6.36E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_01430 8d52641e4860543ad31192009e15997e 375 Gene3D G3DSA:3.60.15.10 119 355 1.5E-48 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_01430 8d52641e4860543ad31192009e15997e 375 Gene3D G3DSA:3.40.250.10 2 111 7.5E-19 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_16670 85590cd9d955c29e29a93f53a31a5056 110 SUPERFAMILY SSF88659 1 99 2.06E-33 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HW35_16670 85590cd9d955c29e29a93f53a31a5056 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 101 2.4E-40 T 12-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like HW35_16670 85590cd9d955c29e29a93f53a31a5056 110 Gene3D G3DSA:1.10.10.10 1 109 5.8E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_16670 85590cd9d955c29e29a93f53a31a5056 110 Hamap MF_00245 UPF0122 protein . 2 103 21.604 T 12-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like HW35_03215 5a0948af529e1e3f7122e2138f6442b4 282 SUPERFAMILY SSF52374 1 280 6.44E-103 T 12-10-2018 HW35_03215 5a0948af529e1e3f7122e2138f6442b4 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 279 6.1E-114 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 HW35_03215 5a0948af529e1e3f7122e2138f6442b4 282 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 38.141 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 HW35_03215 5a0948af529e1e3f7122e2138f6442b4 282 Pfam PF02569 Pantoate-beta-alanine ligase 2 277 5.4E-100 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 HW35_03215 5a0948af529e1e3f7122e2138f6442b4 282 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 77 5.6E-9 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HW35_03215 5a0948af529e1e3f7122e2138f6442b4 282 Gene3D G3DSA:3.40.50.620 1 177 6.5E-75 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_03215 5a0948af529e1e3f7122e2138f6442b4 282 Gene3D G3DSA:3.30.1300.10 178 277 2.2E-31 T 12-10-2018 HW35_16910 0bf7eeb5df4001f75f044f0a9819c80f 251 Pfam PF00574 Clp protease 50 226 1.7E-35 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HW35_16910 0bf7eeb5df4001f75f044f0a9819c80f 251 Gene3D G3DSA:3.90.226.10 34 227 4.3E-32 T 12-10-2018 HW35_16910 0bf7eeb5df4001f75f044f0a9819c80f 251 SUPERFAMILY SSF52096 36 235 1.66E-40 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_07870 2ff0f46ddd2d56d2d8a39c32836c629a 273 Pfam PF13276 HTH-like domain 29 76 1.6E-19 T 12-10-2018 IPR025948 HTH-like domain HW35_07870 2ff0f46ddd2d56d2d8a39c32836c629a 273 SUPERFAMILY SSF53098 100 263 1.32E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_07870 2ff0f46ddd2d56d2d8a39c32836c629a 273 Gene3D G3DSA:3.30.420.10 99 271 2.1E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_07870 2ff0f46ddd2d56d2d8a39c32836c629a 273 Pfam PF00665 Integrase core domain 109 223 8.5E-24 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_13260 b60c34ca046672d988fe09c397684372 191 SUPERFAMILY SSF55729 46 112 6.75E-11 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_13260 b60c34ca046672d988fe09c397684372 191 Pfam PF13508 Acetyltransferase (GNAT) domain 54 110 4.3E-10 T 12-10-2018 IPR000182 GNAT domain HW35_13260 b60c34ca046672d988fe09c397684372 191 Gene3D G3DSA:3.40.630.30 1 135 3.3E-26 T 12-10-2018 HW35_12310 5e20c0d85d5932f384d5020862cf3afc 326 Gene3D G3DSA:3.30.360.10 134 325 3.7E-53 T 12-10-2018 HW35_12310 5e20c0d85d5932f384d5020862cf3afc 326 SUPERFAMILY SSF55347 125 288 8.34E-24 T 12-10-2018 HW35_12310 5e20c0d85d5932f384d5020862cf3afc 326 Gene3D G3DSA:3.40.50.720 1 133 6.4E-37 T 12-10-2018 HW35_12310 5e20c0d85d5932f384d5020862cf3afc 326 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 117 4.0E-28 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 HW35_12310 5e20c0d85d5932f384d5020862cf3afc 326 SUPERFAMILY SSF51735 2 151 1.14E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_08810 f60baf0510c689beb7ee759dbd0281a9 239 Gene3D G3DSA:3.20.20.140 2 206 2.1E-34 T 12-10-2018 HW35_08810 f60baf0510c689beb7ee759dbd0281a9 239 Pfam PF02811 PHP domain 6 109 1.6E-7 T 12-10-2018 IPR004013 PHP domain GO:0003824 HW35_08810 f60baf0510c689beb7ee759dbd0281a9 239 SUPERFAMILY SSF89550 2 194 2.35E-34 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HW35_08810 f60baf0510c689beb7ee759dbd0281a9 239 SMART SM00481 5 71 1.4E-5 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HW35_03180 fccaea931a4889b1c8796a6ae8107e4f 232 Pfam PF07261 Replication initiation and membrane attachment 132 201 2.4E-27 T 12-10-2018 IPR006343 DnaD domain HW35_03180 fccaea931a4889b1c8796a6ae8107e4f 232 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 128 199 2.2E-26 T 12-10-2018 IPR006343 DnaD domain HW35_03180 fccaea931a4889b1c8796a6ae8107e4f 232 SUPERFAMILY SSF158499 129 194 1.96E-20 T 12-10-2018 IPR034829 DnaD-like domain superfamily HW35_03180 fccaea931a4889b1c8796a6ae8107e4f 232 Gene3D G3DSA:1.10.10.10 1 115 1.4E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_03180 fccaea931a4889b1c8796a6ae8107e4f 232 Gene3D G3DSA:1.10.10.630 123 200 1.0E-33 T 12-10-2018 IPR034829 DnaD-like domain superfamily HW35_03180 fccaea931a4889b1c8796a6ae8107e4f 232 SUPERFAMILY SSF46785 28 86 5.12E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_09770 8586ad6639997ea09f323812c778580a 159 SUPERFAMILY SSF75217 2 157 1.57E-62 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases HW35_09770 8586ad6639997ea09f323812c778580a 159 PIRSF PIRSF004505 1 159 7.2E-55 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 HW35_09770 8586ad6639997ea09f323812c778580a 159 Gene3D G3DSA:3.40.1280.10 1 159 3.3E-68 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HW35_09770 8586ad6639997ea09f323812c778580a 159 Pfam PF02590 Predicted SPOUT methyltransferase 2 158 1.7E-60 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 HW35_09770 8586ad6639997ea09f323812c778580a 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 159 6.2E-71 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 HW35_09770 8586ad6639997ea09f323812c778580a 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.924 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 HW35_11875 76826e3d99f67f9ccc7c8985cae424cf 456 Gene3D G3DSA:3.40.50.150 85 450 3.5E-123 T 12-10-2018 HW35_11875 76826e3d99f67f9ccc7c8985cae424cf 456 SUPERFAMILY SSF50249 3 64 3.43E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_11875 76826e3d99f67f9ccc7c8985cae424cf 456 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 438 448 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site HW35_11875 76826e3d99f67f9ccc7c8985cae424cf 456 SUPERFAMILY SSF53335 73 450 7.66E-86 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_11875 76826e3d99f67f9ccc7c8985cae424cf 456 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 279 449 1.9E-20 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 HW35_11875 76826e3d99f67f9ccc7c8985cae424cf 456 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 448 1.1E-166 T 12-10-2018 HW35_11875 76826e3d99f67f9ccc7c8985cae424cf 456 Gene3D G3DSA:2.40.50.140 1 64 1.4E-15 T 12-10-2018 HW35_11875 76826e3d99f67f9ccc7c8985cae424cf 456 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 386 417 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site HW35_11875 76826e3d99f67f9ccc7c8985cae424cf 456 Gene3D G3DSA:3.40.1350.30 132 287 3.5E-123 T 12-10-2018 HW35_10180 62c9974850db944faf475110a4748398 95 SMART SM00465 5 84 0.0011 T 12-10-2018 IPR000305 GIY-YIG endonuclease HW35_10180 62c9974850db944faf475110a4748398 95 Gene3D G3DSA:3.40.1440.10 2 94 9.3E-34 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 HW35_10180 62c9974850db944faf475110a4748398 95 SUPERFAMILY SSF82771 6 76 6.67E-14 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 HW35_10180 62c9974850db944faf475110a4748398 95 Pfam PF01541 GIY-YIG catalytic domain 6 77 6.2E-19 T 12-10-2018 IPR000305 GIY-YIG endonuclease HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 Gene3D G3DSA:2.30.42.10 118 205 1.8E-94 T 12-10-2018 HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 Gene3D G3DSA:3.30.750.44 67 357 1.8E-94 T 12-10-2018 HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 SUPERFAMILY SSF47090 392 460 1.07E-16 T 12-10-2018 IPR036365 PGBD-like superfamily HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 Gene3D G3DSA:3.90.226.10 206 379 1.8E-94 T 12-10-2018 HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 SUPERFAMILY SSF50156 89 211 1.09E-23 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 71 402 3.0E-125 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 SUPERFAMILY SSF52096 55 386 3.98E-73 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 Pfam PF01471 Putative peptidoglycan binding domain 404 459 2.3E-16 T 12-10-2018 IPR002477 Peptidoglycan binding-like HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 Gene3D G3DSA:1.10.101.10 389 471 5.5E-16 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 SMART SM00245 191 382 1.8E-75 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 Pfam PF03572 Peptidase family S41 219 381 4.0E-53 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 SMART SM00228 118 189 1.0E-16 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_07820 e95470a12745528e372a5d8eb96c3b06 485 Pfam PF13180 PDZ domain 119 197 1.1E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 Gene3D G3DSA:3.40.50.880 168 345 3.2E-32 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 SUPERFAMILY SSF52317 136 346 1.8E-51 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00097 Anthranilate synthase component II signature 321 334 2.0E-6 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00097 Anthranilate synthase component II signature 235 246 2.0E-6 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00097 Anthranilate synthase component II signature 208 217 2.0E-6 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 252 269 1.4E-31 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 277 288 1.4E-31 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 235 251 1.4E-31 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 205 219 1.4E-31 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 166 180 1.4E-31 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 Gene3D G3DSA:3.50.30.20 1 145 4.3E-52 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 SUPERFAMILY SSF52021 3 137 5.23E-50 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 346 9.7E-134 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 350 43.685 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 Pfam PF00117 Glutamine amidotransferase class-I 168 343 7.9E-42 T 12-10-2018 IPR017926 Glutamine amidotransferase HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 SMART SM01097 2 132 2.4E-68 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00096 Glutamine amidotransferase superfamily signature 235 246 4.8E-11 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00096 Glutamine amidotransferase superfamily signature 321 334 4.8E-11 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 PRINTS PR00096 Glutamine amidotransferase superfamily signature 208 217 4.8E-11 T 12-10-2018 HW35_14145 0f579f87fb899c3fe8ab7ee4c9a44c9e 357 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 130 3.7E-46 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HW35_04200 9980f5a7c65199c676b221b615609a3c 343 PRINTS PR00812 Bacterial general secretion pathway protein F signature 308 322 3.0E-5 T 12-10-2018 IPR003004 GspF/PilC family HW35_04200 9980f5a7c65199c676b221b615609a3c 343 PRINTS PR00812 Bacterial general secretion pathway protein F signature 324 343 3.0E-5 T 12-10-2018 IPR003004 GspF/PilC family HW35_04200 9980f5a7c65199c676b221b615609a3c 343 PRINTS PR00812 Bacterial general secretion pathway protein F signature 106 134 3.0E-5 T 12-10-2018 IPR003004 GspF/PilC family HW35_04200 9980f5a7c65199c676b221b615609a3c 343 Pfam PF00482 Type II secretion system (T2SS), protein F 14 128 3.5E-12 T 12-10-2018 IPR018076 Type II secretion system F domain HW35_04200 9980f5a7c65199c676b221b615609a3c 343 Pfam PF00482 Type II secretion system (T2SS), protein F 213 335 1.9E-16 T 12-10-2018 IPR018076 Type II secretion system F domain HW35_04200 9980f5a7c65199c676b221b615609a3c 343 Gene3D G3DSA:1.20.81.30 196 311 1.1E-13 T 12-10-2018 HW35_04200 9980f5a7c65199c676b221b615609a3c 343 Gene3D G3DSA:1.20.81.30 1 110 8.6E-11 T 12-10-2018 HW35_10240 a51ad18690661aee0479fed92e579b1a 289 Gene3D G3DSA:3.30.230.10 1 158 1.5E-60 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HW35_10240 a51ad18690661aee0479fed92e579b1a 289 SUPERFAMILY SSF55060 162 281 2.63E-32 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily HW35_10240 a51ad18690661aee0479fed92e579b1a 289 PIRSF PIRSF010376 2 287 3.5E-99 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 HW35_10240 a51ad18690661aee0479fed92e579b1a 289 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 285 8.2E-111 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 HW35_10240 a51ad18690661aee0479fed92e579b1a 289 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 279 36.072 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 HW35_10240 a51ad18690661aee0479fed92e579b1a 289 Pfam PF08544 GHMP kinases C terminal 197 270 1.9E-9 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain HW35_10240 a51ad18690661aee0479fed92e579b1a 289 SUPERFAMILY SSF54211 3 156 7.59E-48 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_10240 a51ad18690661aee0479fed92e579b1a 289 Gene3D G3DSA:3.30.70.890 162 283 1.5E-29 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily HW35_10240 a51ad18690661aee0479fed92e579b1a 289 Pfam PF00288 GHMP kinases N terminal domain 87 144 3.0E-13 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 HW35_01340 5278d370a96311b17c83b61bc6080eaf 256 SMART SM00382 30 205 2.5E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_01340 5278d370a96311b17c83b61bc6080eaf 256 SUPERFAMILY SSF52540 8 222 1.1E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_01340 5278d370a96311b17c83b61bc6080eaf 256 Gene3D G3DSA:3.40.50.300 7 252 4.1E-67 T 12-10-2018 HW35_01340 5278d370a96311b17c83b61bc6080eaf 256 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_01340 5278d370a96311b17c83b61bc6080eaf 256 Pfam PF00005 ABC transporter 21 155 1.9E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_01575 0ae2da941e07219ed5e140cfd4d92a41 132 ProDom PD068105 YNZE MEMBRANE TRANSMEMBRANE 29 128 5.0E-20 T 12-10-2018 IPR020509 Uncharacterised protein family YnzE HW35_01575 0ae2da941e07219ed5e140cfd4d92a41 132 Pfam PF17329 Family of unknown function (DUF5367) 41 128 5.8E-10 T 12-10-2018 IPR020509 Uncharacterised protein family YnzE HW35_08395 65ee7b9e9422bf15de8c27e22b5d53b9 252 SUPERFAMILY SSF51658 1 234 2.21E-42 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily HW35_08395 65ee7b9e9422bf15de8c27e22b5d53b9 252 Gene3D G3DSA:3.20.20.150 1 247 3.7E-67 T 12-10-2018 HW35_05835 0dfaf3cf4c34e1a7245a634a101ce900 527 Pfam PF00501 AMP-binding enzyme 21 423 1.9E-86 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_05835 0dfaf3cf4c34e1a7245a634a101ce900 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 511 1.0E-21 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_05835 0dfaf3cf4c34e1a7245a634a101ce900 527 SUPERFAMILY SSF56801 21 523 2.88E-142 T 12-10-2018 HW35_05835 0dfaf3cf4c34e1a7245a634a101ce900 527 Gene3D G3DSA:3.30.300.310 419 525 5.8E-28 T 12-10-2018 HW35_05835 0dfaf3cf4c34e1a7245a634a101ce900 527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_05835 0dfaf3cf4c34e1a7245a634a101ce900 527 Gene3D G3DSA:3.40.50.12780 2 416 9.4E-116 T 12-10-2018 HW35_05955 3b60a7c2935035ee5a87f4f105a44fcd 262 Hamap MF_01548 UPF0354 protein . 1 262 45.778 T 12-10-2018 IPR010838 Protein of unknown unction DUF1444 HW35_05955 3b60a7c2935035ee5a87f4f105a44fcd 262 Pfam PF07285 Protein of unknown function (DUF1444) 1 262 2.3E-127 T 12-10-2018 IPR010838 Protein of unknown unction DUF1444 HW35_05955 3b60a7c2935035ee5a87f4f105a44fcd 262 PIRSF PIRSF012562 1 262 5.9E-128 T 12-10-2018 IPR010838 Protein of unknown unction DUF1444 HW35_03720 984e43d79fd931553da9a881480edac9 154 Gene3D G3DSA:3.30.1490.190 93 150 1.0E-16 T 12-10-2018 HW35_03720 984e43d79fd931553da9a881480edac9 154 SUPERFAMILY SSF46785 6 141 4.54E-39 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_03720 984e43d79fd931553da9a881480edac9 154 Gene3D G3DSA:1.10.10.10 1 88 2.4E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_03720 984e43d79fd931553da9a881480edac9 154 Pfam PF01475 Ferric uptake regulator family 15 136 6.1E-40 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 HW35_10825 62b52aa0927e69adada32639a66a695e 72 SUPERFAMILY SSF50249 1 71 9.55E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_10825 62b52aa0927e69adada32639a66a695e 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.376 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 HW35_10825 62b52aa0927e69adada32639a66a695e 72 Gene3D G3DSA:2.40.50.140 1 72 1.0E-38 T 12-10-2018 HW35_10825 62b52aa0927e69adada32639a66a695e 72 SMART SM00316 4 72 3.4E-6 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_10825 62b52aa0927e69adada32639a66a695e 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.9E-29 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 HW35_10825 62b52aa0927e69adada32639a66a695e 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 7.5E-40 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 HW35_02710 e647555ebf60a02c951312479b8d124d 93 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 50 2.3E-8 T 12-10-2018 IPR022453 Zinc finger, MqsA-type HW35_02710 e647555ebf60a02c951312479b8d124d 93 TIGRFAM TIGR03829 YokU_near_AblA: uncharacterized protein, YokU family 3 90 1.0E-40 T 12-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU HW35_02710 e647555ebf60a02c951312479b8d124d 93 Pfam PF14122 YokU-like protein, putative antitoxin 3 88 7.3E-40 T 12-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU HW35_11945 81da086fc079bb5a3cd9a20f32e6488a 153 Gene3D G3DSA:2.60.40.420 24 153 9.9E-35 T 12-10-2018 IPR008972 Cupredoxin HW35_11945 81da086fc079bb5a3cd9a20f32e6488a 153 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 98 146 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_11945 81da086fc079bb5a3cd9a20f32e6488a 153 SUPERFAMILY SSF49503 39 152 8.27E-28 T 12-10-2018 IPR008972 Cupredoxin HW35_11945 81da086fc079bb5a3cd9a20f32e6488a 153 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 79 150 2.5E-10 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_12510 0d64d410a22574e2aef4a7f73a76f848 339 Gene3D G3DSA:3.30.360.10 126 320 1.1E-99 T 12-10-2018 HW35_12510 0d64d410a22574e2aef4a7f73a76f848 339 SUPERFAMILY SSF55347 130 300 4.19E-31 T 12-10-2018 HW35_12510 0d64d410a22574e2aef4a7f73a76f848 339 Gene3D G3DSA:3.40.50.720 5 306 1.1E-99 T 12-10-2018 HW35_12510 0d64d410a22574e2aef4a7f73a76f848 339 SUPERFAMILY SSF51735 3 153 3.78E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_12510 0d64d410a22574e2aef4a7f73a76f848 339 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 125 3.6E-26 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 HW35_12510 0d64d410a22574e2aef4a7f73a76f848 339 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 244 2.9E-14 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 HW35_07170 f9a88aa91870fcc5e02a29cdf24bc570 87 Pfam PF10835 Protein of unknown function (DUF2573) 6 80 2.6E-34 T 12-10-2018 IPR020393 Uncharacterised protein family YusU HW35_07170 f9a88aa91870fcc5e02a29cdf24bc570 87 ProDom PD065427 YUSU IG COIL COILED BH3491 1 79 5.0E-22 T 12-10-2018 IPR020393 Uncharacterised protein family YusU HW35_03710 a16cc5e846216d1905431cd076ad781b 76 Pfam PF14004 Protein of unknown function (DUF4227) 7 76 3.7E-32 T 12-10-2018 IPR025321 Protein of unknown function DUF4227 HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 Gene3D G3DSA:3.40.50.300 288 517 2.5E-42 T 12-10-2018 HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 SMART SM00382 349 514 1.4E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 SMART SM00382 28 252 2.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 Gene3D G3DSA:3.40.50.300 2 285 1.1E-62 T 12-10-2018 HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 Pfam PF12848 ABC transporter 230 315 4.5E-23 T 12-10-2018 IPR032781 ABC-transporter extension domain HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 Pfam PF00005 ABC transporter 20 191 8.3E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 SUPERFAMILY SSF52540 326 510 1.48E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 Pfam PF00005 ABC transporter 342 468 3.1E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_00885 57f4e95fbbad88cf135de0f63d1527c5 517 SUPERFAMILY SSF52540 4 233 6.32E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13065 f2537409a48f8308bc95c838162e37b8 188 SUPERFAMILY SSF56349 9 179 2.35E-30 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HW35_13065 f2537409a48f8308bc95c838162e37b8 188 Gene3D G3DSA:1.10.443.10 6 174 3.6E-25 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 HW35_13065 f2537409a48f8308bc95c838162e37b8 188 Pfam PF00589 Phage integrase family 11 172 1.1E-19 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HW35_10860 e5e8a44a1971052735b665a4186783d2 289 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_10860 e5e8a44a1971052735b665a4186783d2 289 Pfam PF00005 ABC transporter 24 174 8.6E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_10860 e5e8a44a1971052735b665a4186783d2 289 SMART SM00382 32 223 2.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_10860 e5e8a44a1971052735b665a4186783d2 289 Gene3D G3DSA:3.40.50.300 1 283 1.2E-78 T 12-10-2018 HW35_10860 e5e8a44a1971052735b665a4186783d2 289 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 280 2.2E-121 T 12-10-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 HW35_10860 e5e8a44a1971052735b665a4186783d2 289 SUPERFAMILY SSF52540 4 240 1.62E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14310 dc9fbe098cc0c3222e58d7da9d781d23 155 SUPERFAMILY SSF52833 4 153 6.07E-59 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_14310 dc9fbe098cc0c3222e58d7da9d781d23 155 PIRSF PIRSF000239 1 142 1.3E-31 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HW35_14310 dc9fbe098cc0c3222e58d7da9d781d23 155 Gene3D G3DSA:3.40.30.10 1 154 1.9E-58 T 12-10-2018 HW35_14310 dc9fbe098cc0c3222e58d7da9d781d23 155 Pfam PF00578 AhpC/TSA family 5 132 1.2E-45 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HW35_17340 02f1c86fbe057b7dc134862ce5d9e835 102 Pfam PF14074 Protein of unknown function (DUF4257) 5 82 9.8E-28 T 12-10-2018 IPR025353 Protein of unknown function DUF4257) HW35_17340 02f1c86fbe057b7dc134862ce5d9e835 102 ProDom PD866859 YTVB PLASMID MEMBRANE TRANSMEMBRANE 20 90 8.0E-10 T 12-10-2018 HW35_12270 c953fdb0bac805df3993220dcddddcbb 254 Pfam PF00005 ABC transporter 23 171 3.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12270 c953fdb0bac805df3993220dcddddcbb 254 SUPERFAMILY SSF52540 3 226 2.46E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12270 c953fdb0bac805df3993220dcddddcbb 254 SMART SM00382 32 220 5.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_12270 c953fdb0bac805df3993220dcddddcbb 254 Gene3D G3DSA:3.40.50.300 2 247 5.4E-66 T 12-10-2018 HW35_05830 3e057d259b44ad635e78f3b11ec90c04 266 Pfam PF01513 ATP-NAD kinase 41 251 3.4E-13 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HW35_05830 3e057d259b44ad635e78f3b11ec90c04 266 Gene3D G3DSA:2.60.200.30 108 244 3.5E-73 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HW35_05830 3e057d259b44ad635e78f3b11ec90c04 266 Gene3D G3DSA:3.40.50.10330 34 266 3.5E-73 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 HW35_05830 3e057d259b44ad635e78f3b11ec90c04 266 SUPERFAMILY SSF111331 12 265 4.09E-55 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily HW35_05830 3e057d259b44ad635e78f3b11ec90c04 266 Hamap MF_00361 NAD kinase [nadK]. 5 266 20.456 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HW35_00105 6a11b4ccfa2e548c4c278222ed3ebf26 359 Gene3D G3DSA:3.90.1150.10 26 351 5.6E-108 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_00105 6a11b4ccfa2e548c4c278222ed3ebf26 359 Pfam PF00155 Aminotransferase class I and II 26 349 2.0E-47 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HW35_00105 6a11b4ccfa2e548c4c278222ed3ebf26 359 SUPERFAMILY SSF53383 3 353 1.09E-77 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_00105 6a11b4ccfa2e548c4c278222ed3ebf26 359 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 6 352 4.9E-95 T 12-10-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 HW35_00105 6a11b4ccfa2e548c4c278222ed3ebf26 359 Gene3D G3DSA:3.40.640.10 37 259 5.6E-108 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_00105 6a11b4ccfa2e548c4c278222ed3ebf26 359 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 211 224 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 HW35_01940 8d178bbb1540da80a53054e6891d89af 451 Pfam PF05525 Branched-chain amino acid transport protein 9 441 1.5E-157 T 12-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 HW35_01940 8d178bbb1540da80a53054e6891d89af 451 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 429 1.3E-147 T 12-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 HW35_11685 73903fdf222295a9fb75ac591405a3ff 384 Gene3D G3DSA:3.30.470.20 188 377 2.8E-80 T 12-10-2018 HW35_11685 73903fdf222295a9fb75ac591405a3ff 384 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 13 362 43.306 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 HW35_11685 73903fdf222295a9fb75ac591405a3ff 384 SUPERFAMILY SSF52440 10 96 2.16E-25 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HW35_11685 73903fdf222295a9fb75ac591405a3ff 384 SUPERFAMILY SSF56059 109 308 6.89E-64 T 12-10-2018 HW35_11685 73903fdf222295a9fb75ac591405a3ff 384 SUPERFAMILY SSF51246 311 375 7.38E-16 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 HW35_11685 73903fdf222295a9fb75ac591405a3ff 384 Pfam PF02222 ATP-grasp domain 118 287 1.1E-56 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type HW35_11685 73903fdf222295a9fb75ac591405a3ff 384 Gene3D G3DSA:3.40.50.20 2 118 1.5E-45 T 12-10-2018 HW35_11685 73903fdf222295a9fb75ac591405a3ff 384 Gene3D G3DSA:3.30.1490.20 119 187 6.6E-24 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HW35_11685 73903fdf222295a9fb75ac591405a3ff 384 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 13 365 1.5E-128 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 HW35_14285 abf4f7881191b300157c94a207feab1c 431 SUPERFAMILY SSF53383 3 427 6.79E-127 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_14285 abf4f7881191b300157c94a207feab1c 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_14285 abf4f7881191b300157c94a207feab1c 431 Pfam PF00202 Aminotransferase class-III 35 399 4.2E-71 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_14285 abf4f7881191b300157c94a207feab1c 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 95.361 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 HW35_14285 abf4f7881191b300157c94a207feab1c 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 426 3.0E-172 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 HW35_14285 abf4f7881191b300157c94a207feab1c 431 Gene3D G3DSA:3.40.640.10 72 320 3.8E-172 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_14285 abf4f7881191b300157c94a207feab1c 431 Gene3D G3DSA:3.90.1150.10 9 423 3.8E-172 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_06120 e3bc3f834b36efd35fbcfdec6b86bb92 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 131 152 1.9E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 HW35_06120 e3bc3f834b36efd35fbcfdec6b86bb92 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 348 371 1.9E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 HW35_06120 e3bc3f834b36efd35fbcfdec6b86bb92 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 7 29 1.9E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 HW35_06120 e3bc3f834b36efd35fbcfdec6b86bb92 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 92 110 1.9E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 HW35_06120 e3bc3f834b36efd35fbcfdec6b86bb92 397 SUPERFAMILY SSF103473 3 387 3.01E-52 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_06120 e3bc3f834b36efd35fbcfdec6b86bb92 397 Gene3D G3DSA:1.20.1250.20 191 396 2.6E-22 T 12-10-2018 HW35_06120 e3bc3f834b36efd35fbcfdec6b86bb92 397 Gene3D G3DSA:1.20.1250.20 1 190 5.3E-26 T 12-10-2018 HW35_06120 e3bc3f834b36efd35fbcfdec6b86bb92 397 Pfam PF07690 Major Facilitator Superfamily 8 227 3.9E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_14065 944ab91ec61c64cf4f9b22812e4d9e66 239 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 2 225 5.5E-69 T 12-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 HW35_14065 944ab91ec61c64cf4f9b22812e4d9e66 239 Gene3D G3DSA:1.20.950.20 1 218 1.3E-76 T 12-10-2018 HW35_14065 944ab91ec61c64cf4f9b22812e4d9e66 239 SUPERFAMILY SSF103501 2 225 3.27E-66 T 12-10-2018 IPR036197 NarG-like superfamily HW35_14065 944ab91ec61c64cf4f9b22812e4d9e66 239 Pfam PF02665 Nitrate reductase gamma subunit 6 225 1.2E-83 T 12-10-2018 IPR023234 NarG-like domain HW35_01880 a001f846b158ff743a1dad234b48e32d 500 SUPERFAMILY SSF56176 20 233 1.26E-68 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 HW35_01880 a001f846b158ff743a1dad234b48e32d 500 Gene3D G3DSA:3.30.465.40 27 252 7.5E-68 T 12-10-2018 HW35_01880 a001f846b158ff743a1dad234b48e32d 500 Gene3D G3DSA:3.30.70.2740 354 434 2.1E-7 T 12-10-2018 HW35_01880 a001f846b158ff743a1dad234b48e32d 500 Pfam PF01565 FAD binding domain 57 195 2.3E-40 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HW35_01880 a001f846b158ff743a1dad234b48e32d 500 Pfam PF02913 FAD linked oxidases, C-terminal domain 232 474 5.0E-58 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HW35_01880 a001f846b158ff743a1dad234b48e32d 500 SUPERFAMILY SSF55103 236 481 2.45E-61 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HW35_01880 a001f846b158ff743a1dad234b48e32d 500 Gene3D G3DSA:1.10.45.10 435 474 2.4E-5 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HW35_15305 2aa971382fa74da57fc4889ca48d1ddc 558 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 98 119 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site HW35_15305 2aa971382fa74da57fc4889ca48d1ddc 558 Gene3D G3DSA:3.90.76.10 80 205 1.1E-172 T 12-10-2018 HW35_15305 2aa971382fa74da57fc4889ca48d1ddc 558 SUPERFAMILY SSF53850 45 553 2.35E-121 T 12-10-2018 HW35_15305 2aa971382fa74da57fc4889ca48d1ddc 558 Gene3D G3DSA:3.40.190.10 61 546 1.1E-172 T 12-10-2018 HW35_15305 2aa971382fa74da57fc4889ca48d1ddc 558 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 477 1.1E-76 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain HW35_15305 2aa971382fa74da57fc4889ca48d1ddc 558 Gene3D G3DSA:3.10.105.10 309 529 1.1E-172 T 12-10-2018 HW35_15305 2aa971382fa74da57fc4889ca48d1ddc 558 PIRSF PIRSF002741 2 557 4.5E-100 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HW35_16050 fe234da75c419c24c8716ed78ea304d3 437 SUPERFAMILY SSF52540 20 417 7.97E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16050 fe234da75c419c24c8716ed78ea304d3 437 Gene3D G3DSA:3.40.50.300 226 436 5.2E-69 T 12-10-2018 HW35_16050 fe234da75c419c24c8716ed78ea304d3 437 Pfam PF13638 PIN domain 1 142 5.5E-32 T 12-10-2018 IPR002716 PIN domain HW35_16050 fe234da75c419c24c8716ed78ea304d3 437 SMART SM00670 1 130 1.5E-19 T 12-10-2018 IPR002716 PIN domain HW35_16050 fe234da75c419c24c8716ed78ea304d3 437 Pfam PF02562 PhoH-like protein 228 428 7.3E-55 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 HW35_16050 fe234da75c419c24c8716ed78ea304d3 437 Gene3D G3DSA:3.40.50.1010 1 145 1.0E-19 T 12-10-2018 HW35_05170 0b0ae84d1c17396c89433884d54ee653 576 SUPERFAMILY SSF55073 409 574 9.42E-44 T 12-10-2018 IPR029787 Nucleotide cyclase HW35_05170 0b0ae84d1c17396c89433884d54ee653 576 Pfam PF00990 Diguanylate cyclase, GGDEF domain 408 569 2.2E-45 T 12-10-2018 IPR000160 GGDEF domain HW35_05170 0b0ae84d1c17396c89433884d54ee653 576 SUPERFAMILY SSF55781 235 403 3.49E-20 T 12-10-2018 HW35_05170 0b0ae84d1c17396c89433884d54ee653 576 Pfam PF13185 GAF domain 252 392 1.7E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 HW35_05170 0b0ae84d1c17396c89433884d54ee653 576 Gene3D G3DSA:3.30.450.40 229 401 7.2E-24 T 12-10-2018 IPR029016 GAF-like domain superfamily HW35_05170 0b0ae84d1c17396c89433884d54ee653 576 Gene3D G3DSA:3.30.70.270 402 574 1.4E-52 T 12-10-2018 HW35_05170 0b0ae84d1c17396c89433884d54ee653 576 SMART SM00065 252 401 3.6E-4 T 12-10-2018 IPR003018 GAF domain GO:0005515 HW35_05170 0b0ae84d1c17396c89433884d54ee653 576 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 403 571 1.5E-44 T 12-10-2018 IPR000160 GGDEF domain HW35_05170 0b0ae84d1c17396c89433884d54ee653 576 SMART SM00267 393 573 1.7E-53 T 12-10-2018 IPR000160 GGDEF domain HW35_00500 8868cf54d68690ece1eab7a9854102a5 283 Gene3D G3DSA:1.10.220.30 128 282 1.5E-7 T 12-10-2018 HW35_00500 8868cf54d68690ece1eab7a9854102a5 283 SUPERFAMILY SSF48029 130 271 3.14E-7 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HW35_14195 2697b68e5f5691ee6c37cba6aaf0938a 269 Gene3D G3DSA:1.10.10.10 112 156 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_14195 2697b68e5f5691ee6c37cba6aaf0938a 269 Gene3D G3DSA:1.10.10.10 157 219 1.9E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_14195 2697b68e5f5691ee6c37cba6aaf0938a 269 Gene3D G3DSA:1.10.10.10 220 269 2.7E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_14195 2697b68e5f5691ee6c37cba6aaf0938a 269 Pfam PF02631 RecX family 88 208 2.6E-31 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 HW35_14195 2697b68e5f5691ee6c37cba6aaf0938a 269 Pfam PF02631 RecX family 213 266 3.2E-5 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 HW35_14195 2697b68e5f5691ee6c37cba6aaf0938a 269 Hamap MF_01114 Regulatory protein RecX [recX]. 46 213 18.167 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 HW35_14195 2697b68e5f5691ee6c37cba6aaf0938a 269 Gene3D G3DSA:1.10.10.2800 1 111 6.0E-37 T 12-10-2018 HW35_10085 759fb64cd841c830223a858bf76a6e57 162 Pfam PF14437 MafB19-like deaminase 5 150 1.7E-44 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 HW35_10085 759fb64cd841c830223a858bf76a6e57 162 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 91 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HW35_10085 759fb64cd841c830223a858bf76a6e57 162 Gene3D G3DSA:3.40.140.10 1 162 1.7E-64 T 12-10-2018 HW35_10085 759fb64cd841c830223a858bf76a6e57 162 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 9 150 46.416 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 HW35_10085 759fb64cd841c830223a858bf76a6e57 162 SUPERFAMILY SSF53927 3 154 2.17E-55 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 HW35_06210 eea271f1756f31bbfa77120ea92771f7 122 Gene3D G3DSA:2.30.29.50 8 122 1.0E-35 T 12-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily HW35_06210 eea271f1756f31bbfa77120ea92771f7 122 Pfam PF08000 Bacterial PH domain 9 120 1.6E-33 T 12-10-2018 IPR012544 Bacterial Pleckstrin homology domain HW35_06210 eea271f1756f31bbfa77120ea92771f7 122 SUPERFAMILY SSF50729 9 122 1.35E-36 T 12-10-2018 HW35_15270 143bf05554bcac38f7b20a906a0c66b5 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 4.0E-29 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_15270 143bf05554bcac38f7b20a906a0c66b5 321 SUPERFAMILY SSF52540 39 318 1.16E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15270 143bf05554bcac38f7b20a906a0c66b5 321 SMART SM00382 40 232 5.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_15270 143bf05554bcac38f7b20a906a0c66b5 321 Gene3D G3DSA:3.40.50.300 2 321 1.3E-102 T 12-10-2018 HW35_15270 143bf05554bcac38f7b20a906a0c66b5 321 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_15270 143bf05554bcac38f7b20a906a0c66b5 321 Pfam PF00005 ABC transporter 32 182 1.0E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_15270 143bf05554bcac38f7b20a906a0c66b5 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 1.5E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_00590 122aafd13b4780cdbec81256f7bcd55d 112 Gene3D G3DSA:1.20.58.1000 11 111 2.3E-29 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily HW35_00590 122aafd13b4780cdbec81256f7bcd55d 112 Pfam PF02583 Metal-sensitive transcriptional repressor 30 108 2.3E-27 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 HW35_15745 3eeeb3aabdd7d9554e0db41cc9a993d5 146 Gene3D G3DSA:1.10.10.10 1 140 1.6E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_15745 3eeeb3aabdd7d9554e0db41cc9a993d5 146 Pfam PF01047 MarR family 36 93 6.3E-18 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_15745 3eeeb3aabdd7d9554e0db41cc9a993d5 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_15745 3eeeb3aabdd7d9554e0db41cc9a993d5 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_15745 3eeeb3aabdd7d9554e0db41cc9a993d5 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_15745 3eeeb3aabdd7d9554e0db41cc9a993d5 146 SMART SM00347 29 129 1.5E-29 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_15745 3eeeb3aabdd7d9554e0db41cc9a993d5 146 SUPERFAMILY SSF46785 7 139 4.23E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_15745 3eeeb3aabdd7d9554e0db41cc9a993d5 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site HW35_04475 ee8398c09ed971cf1cc199021fc51c7e 116 Pfam PF01219 Prokaryotic diacylglycerol kinase 2 102 7.7E-36 T 12-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 HW35_04475 ee8398c09ed971cf1cc199021fc51c7e 116 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 55 66 - T 12-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 HW35_04475 ee8398c09ed971cf1cc199021fc51c7e 116 Gene3D G3DSA:1.10.3830.10 1 106 7.1E-37 T 12-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 HW35_07740 a9f5629b2e7173b62abc7960419a7b04 560 Pfam PF00144 Beta-lactamase 82 414 1.5E-80 T 12-10-2018 IPR001466 Beta-lactamase-related HW35_07740 a9f5629b2e7173b62abc7960419a7b04 560 Gene3D G3DSA:3.40.710.10 61 429 1.8E-102 T 12-10-2018 HW35_07740 a9f5629b2e7173b62abc7960419a7b04 560 Pfam PF05547 Immune inhibitor A peptidase M6 442 541 1.5E-8 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 HW35_07740 a9f5629b2e7173b62abc7960419a7b04 560 SUPERFAMILY SSF56601 72 434 8.45E-96 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_09345 01fa565453dac811af6c1e33cf11447d 64 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 60 3.6E-28 T 12-10-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 HW35_09345 01fa565453dac811af6c1e33cf11447d 64 Gene3D G3DSA:3.30.429.10 1 60 6.2E-28 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily HW35_09345 01fa565453dac811af6c1e33cf11447d 64 SUPERFAMILY SSF55331 2 60 1.83E-20 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily HW35_09345 01fa565453dac811af6c1e33cf11447d 64 Pfam PF01361 Tautomerase enzyme 2 60 3.0E-25 T 12-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 HW35_03615 45b1fe11eb9d5476184331675b2fd74f 194 SUPERFAMILY SSF46785 3 81 1.22E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_03615 45b1fe11eb9d5476184331675b2fd74f 194 Hamap MF_01804 Segregation and condensation protein B [scpB]. 4 184 37.123 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HW35_03615 45b1fe11eb9d5476184331675b2fd74f 194 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 168 9.4E-60 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HW35_03615 45b1fe11eb9d5476184331675b2fd74f 194 PIRSF PIRSF019345 1 192 9.6E-59 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HW35_03615 45b1fe11eb9d5476184331675b2fd74f 194 SUPERFAMILY SSF46785 85 159 4.08E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_03615 45b1fe11eb9d5476184331675b2fd74f 194 Gene3D G3DSA:1.10.10.10 3 83 1.0E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_03615 45b1fe11eb9d5476184331675b2fd74f 194 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 5 189 1.5E-57 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HW35_03615 45b1fe11eb9d5476184331675b2fd74f 194 Gene3D G3DSA:1.10.10.10 84 180 2.8E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_05705 a927b681916e6a141f74c887b275c099 210 SUPERFAMILY SSF46785 4 77 2.83E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_05705 a927b681916e6a141f74c887b275c099 210 Gene3D G3DSA:1.20.120.530 92 208 1.3E-7 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal HW35_05705 a927b681916e6a141f74c887b275c099 210 SMART SM00345 14 73 6.8E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_05705 a927b681916e6a141f74c887b275c099 210 Pfam PF07729 FCD domain 98 197 1.5E-5 T 12-10-2018 IPR011711 GntR, C-terminal HW35_05705 a927b681916e6a141f74c887b275c099 210 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 8.2E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_05705 a927b681916e6a141f74c887b275c099 210 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 8.2E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_05705 a927b681916e6a141f74c887b275c099 210 SUPERFAMILY SSF48008 97 201 1.88E-7 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal HW35_05705 a927b681916e6a141f74c887b275c099 210 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 7.1E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_05705 a927b681916e6a141f74c887b275c099 210 Gene3D G3DSA:1.10.10.10 2 80 1.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_00835 7c36065e2bc6686ed6c4fbca7a574a22 352 Gene3D G3DSA:1.10.287.70 2 100 8.5E-18 T 12-10-2018 HW35_00835 7c36065e2bc6686ed6c4fbca7a574a22 352 SUPERFAMILY SSF51735 116 262 8.27E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_00835 7c36065e2bc6686ed6c4fbca7a574a22 352 Pfam PF02254 TrkA-N domain 118 249 2.5E-10 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HW35_00835 7c36065e2bc6686ed6c4fbca7a574a22 352 SUPERFAMILY SSF81324 14 140 2.09E-23 T 12-10-2018 HW35_00835 7c36065e2bc6686ed6c4fbca7a574a22 352 Pfam PF07885 Ion channel 24 96 1.0E-13 T 12-10-2018 IPR013099 Potassium channel domain HW35_00835 7c36065e2bc6686ed6c4fbca7a574a22 352 Gene3D G3DSA:3.40.50.720 112 264 5.2E-23 T 12-10-2018 HW35_14950 6c5138003d14299afcad5c14ba1c5185 403 Pfam PF05975 Bacterial ABC transporter protein EcsB 5 386 2.1E-120 T 12-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 HW35_14950 6c5138003d14299afcad5c14ba1c5185 403 PIRSF PIRSF037259 2 403 1.1E-120 T 12-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 HW35_08415 c5ab743c6281d423ce0d8008697ed582 186 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 95 110 0.24 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_08415 c5ab743c6281d423ce0d8008697ed582 186 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 130 165 2.6E-10 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_08415 c5ab743c6281d423ce0d8008697ed582 186 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 HW35_08415 c5ab743c6281d423ce0d8008697ed582 186 SUPERFAMILY SSF51161 1 184 2.77E-54 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily HW35_08415 c5ab743c6281d423ce0d8008697ed582 186 Gene3D G3DSA:2.160.10.10 1 186 2.6E-71 T 12-10-2018 HW35_08415 c5ab743c6281d423ce0d8008697ed582 186 SMART SM01266 5 59 2.3E-22 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 HW35_08415 c5ab743c6281d423ce0d8008697ed582 186 Pfam PF12464 Maltose acetyltransferase 7 58 3.4E-17 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 HW35_12490 4973e8e1a5d3e2053ed7200c1ff54387 392 Pfam PF00999 Sodium/hydrogen exchanger family 7 373 1.7E-78 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 HW35_12490 4973e8e1a5d3e2053ed7200c1ff54387 392 Gene3D G3DSA:1.20.1530.20 1 382 9.3E-105 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily HW35_04220 0c76133c1a29fb955a1b20725cd80a3a 364 SUPERFAMILY SSF53335 12 352 3.26E-80 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_04220 0c76133c1a29fb955a1b20725cd80a3a 364 Gene3D G3DSA:3.40.50.12710 2 364 5.0E-92 T 12-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 HW35_04220 0c76133c1a29fb955a1b20725cd80a3a 364 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 62 288 2.4E-40 T 12-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 HW35_07610 180067729535ea96085c3ec353d44a49 152 Gene3D G3DSA:3.90.79.10 1 152 2.3E-42 T 12-10-2018 HW35_07610 180067729535ea96085c3ec353d44a49 152 SUPERFAMILY SSF55811 4 130 8.8E-28 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 HW35_07610 180067729535ea96085c3ec353d44a49 152 PRINTS PR00502 NUDIX hydrolase family signature 40 55 1.1E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HW35_07610 180067729535ea96085c3ec353d44a49 152 PRINTS PR00502 NUDIX hydrolase family signature 26 40 1.1E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HW35_07610 180067729535ea96085c3ec353d44a49 152 Pfam PF00293 NUDIX domain 3 123 2.5E-18 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HW35_08380 c02097ef06f7b55f85aa6d6c7d771ec4 212 SUPERFAMILY SSF51569 5 201 1.06E-62 T 12-10-2018 HW35_08380 c02097ef06f7b55f85aa6d6c7d771ec4 212 Gene3D G3DSA:3.20.20.70 3 209 1.7E-74 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_08380 c02097ef06f7b55f85aa6d6c7d771ec4 212 Pfam PF01081 KDPG and KHG aldolase 5 184 1.4E-44 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 HW35_08380 c02097ef06f7b55f85aa6d6c7d771ec4 212 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 5 203 5.0E-57 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 HW35_02570 5ff2815dc5db75bd16d8164ad35db180 468 Pfam PF04715 Anthranilate synthase component I, N terminal region 15 151 8.1E-37 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_02570 5ff2815dc5db75bd16d8164ad35db180 468 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 15 458 2.5E-178 T 12-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_02570 5ff2815dc5db75bd16d8164ad35db180 468 Gene3D G3DSA:3.60.120.10 7 458 1.3E-169 T 12-10-2018 IPR005801 ADC synthase GO:0009058 HW35_02570 5ff2815dc5db75bd16d8164ad35db180 468 Pfam PF00425 chorismate binding enzyme 199 452 4.8E-98 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal HW35_02570 5ff2815dc5db75bd16d8164ad35db180 468 SUPERFAMILY SSF56322 7 458 1.28E-152 T 12-10-2018 IPR005801 ADC synthase GO:0009058 HW35_02570 5ff2815dc5db75bd16d8164ad35db180 468 PRINTS PR00095 Anthranilate synthase component I signature 394 408 6.0E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_02570 5ff2815dc5db75bd16d8164ad35db180 468 PRINTS PR00095 Anthranilate synthase component I signature 409 423 6.0E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_02570 5ff2815dc5db75bd16d8164ad35db180 468 PRINTS PR00095 Anthranilate synthase component I signature 314 327 6.0E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_02570 5ff2815dc5db75bd16d8164ad35db180 468 PRINTS PR00095 Anthranilate synthase component I signature 300 313 6.0E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HW35_02585 6db0aee0d25e6ecf5279b7804c74b81a 304 PIRSF PIRSF000535 1 303 1.2E-90 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 HW35_02585 6db0aee0d25e6ecf5279b7804c74b81a 304 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 9.4E-113 T 12-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 HW35_02585 6db0aee0d25e6ecf5279b7804c74b81a 304 SUPERFAMILY SSF53613 1 283 3.43E-66 T 12-10-2018 IPR029056 Ribokinase-like HW35_02585 6db0aee0d25e6ecf5279b7804c74b81a 304 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HW35_02585 6db0aee0d25e6ecf5279b7804c74b81a 304 Gene3D G3DSA:3.40.1190.20 1 303 1.9E-109 T 12-10-2018 IPR029056 Ribokinase-like HW35_02585 6db0aee0d25e6ecf5279b7804c74b81a 304 Pfam PF00294 pfkB family carbohydrate kinase 10 281 3.3E-56 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB HW35_02585 6db0aee0d25e6ecf5279b7804c74b81a 304 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 5.3E-112 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 HW35_11195 81abe485aaf0bd69114d9ad654f5426c 112 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 6 99 8.9E-36 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 HW35_11195 81abe485aaf0bd69114d9ad654f5426c 112 PIRSF PIRSF000699 1 105 3.3E-36 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 HW35_11195 81abe485aaf0bd69114d9ad654f5426c 112 Gene3D G3DSA:1.20.58.280 1 103 1.5E-37 T 12-10-2018 HW35_11195 81abe485aaf0bd69114d9ad654f5426c 112 SUPERFAMILY SSF46973 2 100 1.7E-35 T 12-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 HW35_02795 311d1529fdc72a074382fbb51a454dd9 296 SUPERFAMILY SSF56281 7 253 1.62E-31 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_02795 311d1529fdc72a074382fbb51a454dd9 296 Gene3D G3DSA:3.60.15.10 7 237 4.9E-27 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_02795 311d1529fdc72a074382fbb51a454dd9 296 SMART SM00849 20 208 5.4E-14 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_02795 311d1529fdc72a074382fbb51a454dd9 296 Pfam PF00753 Metallo-beta-lactamase superfamily 29 208 7.6E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_00065 bd432072eba59842190028f92010f9ec 219 Gene3D G3DSA:2.40.30.20 1 88 8.2E-33 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_00065 bd432072eba59842190028f92010f9ec 219 PIRSF PIRSF000498 1 212 2.2E-76 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HW35_00065 bd432072eba59842190028f92010f9ec 219 SUPERFAMILY SSF63380 92 195 2.55E-32 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel HW35_00065 bd432072eba59842190028f92010f9ec 219 Pfam PF00677 Lumazine binding domain 3 86 2.5E-24 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HW35_00065 bd432072eba59842190028f92010f9ec 219 Pfam PF00677 Lumazine binding domain 99 183 1.4E-21 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HW35_00065 bd432072eba59842190028f92010f9ec 219 SUPERFAMILY SSF63380 1 90 1.36E-29 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel HW35_00065 bd432072eba59842190028f92010f9ec 219 Gene3D G3DSA:2.40.30.20 101 204 1.4E-30 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HW35_00065 bd432072eba59842190028f92010f9ec 219 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 197 3.6E-80 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HW35_11260 65e775beb615910ac08e366f4d131fbe 145 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 142 2.1E-38 T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_11260 65e775beb615910ac08e366f4d131fbe 145 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 49 65 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_11260 65e775beb615910ac08e366f4d131fbe 145 Gene3D G3DSA:3.40.930.10 3 144 1.8E-46 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_11260 65e775beb615910ac08e366f4d131fbe 145 SUPERFAMILY SSF55804 5 143 4.71E-44 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_16095 f5150ec514851f15204b66843ef72524 353 SUPERFAMILY SSF49503 120 278 1.34E-41 T 12-10-2018 IPR008972 Cupredoxin HW35_16095 f5150ec514851f15204b66843ef72524 353 SUPERFAMILY SSF81464 16 117 5.56E-22 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16095 f5150ec514851f15204b66843ef72524 353 SUPERFAMILY SSF46626 250 349 9.05E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HW35_16095 f5150ec514851f15204b66843ef72524 353 Gene3D G3DSA:2.60.40.2600 123 353 4.6E-66 T 12-10-2018 HW35_16095 f5150ec514851f15204b66843ef72524 353 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 34 241 7.7E-53 T 12-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16095 f5150ec514851f15204b66843ef72524 353 PRINTS PR01166 Cytochrome c oxidase subunit II signature 96 116 2.6E-8 T 12-10-2018 HW35_16095 f5150ec514851f15204b66843ef72524 353 PRINTS PR01166 Cytochrome c oxidase subunit II signature 84 96 2.6E-8 T 12-10-2018 HW35_16095 f5150ec514851f15204b66843ef72524 353 PRINTS PR01166 Cytochrome c oxidase subunit II signature 214 231 2.6E-8 T 12-10-2018 HW35_16095 f5150ec514851f15204b66843ef72524 353 Pfam PF00034 Cytochrome c 258 350 2.8E-11 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16095 f5150ec514851f15204b66843ef72524 353 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 47 107 1.3E-11 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16095 f5150ec514851f15204b66843ef72524 353 Gene3D G3DSA:1.10.287.90 28 116 1.0E-23 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16095 f5150ec514851f15204b66843ef72524 353 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 150 231 1.7E-13 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16095 f5150ec514851f15204b66843ef72524 353 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 171 225 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_15705 02bd0f9cfa87bf18ba342eb6cb31ef7f 70 Pfam PF09388 Spo0E like sporulation regulatory protein 3 42 1.1E-15 T 12-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 HW35_15705 02bd0f9cfa87bf18ba342eb6cb31ef7f 70 SUPERFAMILY SSF140500 1 47 3.14E-14 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 HW35_15705 02bd0f9cfa87bf18ba342eb6cb31ef7f 70 Gene3D G3DSA:1.20.58.990 1 55 5.7E-12 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 HW35_15105 16bb7c76efb77619b163aec1ec77a073 120 Hamap MF_01536 UPF0344 protein . 1 119 14.641 T 12-10-2018 IPR010899 Protein of unknown function UPF0344 HW35_15105 16bb7c76efb77619b163aec1ec77a073 120 Pfam PF07457 Protein of unknown function (DUF1516) 2 108 3.4E-32 T 12-10-2018 IPR010899 Protein of unknown function UPF0344 HW35_15105 16bb7c76efb77619b163aec1ec77a073 120 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 115 1.0E-7 T 12-10-2018 IPR010899 Protein of unknown function UPF0344 HW35_01825 53d011db02e0635e371b511f286f5cf7 284 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_01825 53d011db02e0635e371b511f286f5cf7 284 SUPERFAMILY SSF52540 6 237 4.9E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_01825 53d011db02e0635e371b511f286f5cf7 284 SMART SM00382 33 221 5.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_01825 53d011db02e0635e371b511f286f5cf7 284 Pfam PF00005 ABC transporter 24 175 3.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_01825 53d011db02e0635e371b511f286f5cf7 284 Gene3D G3DSA:3.40.50.300 3 279 5.6E-77 T 12-10-2018 HW35_04650 6534bb15e1495095e0cf7ced20ecae2f 279 SUPERFAMILY SSF53223 3 101 8.06E-36 T 12-10-2018 HW35_04650 6534bb15e1495095e0cf7ced20ecae2f 279 SUPERFAMILY SSF51735 102 273 4.89E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_04650 6534bb15e1495095e0cf7ced20ecae2f 279 Gene3D G3DSA:3.40.50.10860 5 260 2.2E-96 T 12-10-2018 HW35_04650 6534bb15e1495095e0cf7ced20ecae2f 279 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 115 193 4.6E-10 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase HW35_04650 6534bb15e1495095e0cf7ced20ecae2f 279 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 272 35.684 T 12-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 HW35_04650 6534bb15e1495095e0cf7ced20ecae2f 279 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 3.7E-30 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 HW35_04650 6534bb15e1495095e0cf7ced20ecae2f 279 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 274 2.5E-92 T 12-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 HW35_04650 6534bb15e1495095e0cf7ced20ecae2f 279 Gene3D G3DSA:3.40.50.720 101 240 2.2E-96 T 12-10-2018 HW35_11700 c9e5d4d15e655404e4ac50497bbd5e11 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 3.3E-31 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HW35_11700 c9e5d4d15e655404e4ac50497bbd5e11 84 Gene3D G3DSA:3.30.1280.10 1 84 1.3E-35 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11700 c9e5d4d15e655404e4ac50497bbd5e11 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 5.0E-26 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HW35_11700 c9e5d4d15e655404e4ac50497bbd5e11 84 SUPERFAMILY SSF82697 1 80 1.33E-29 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HW35_11700 c9e5d4d15e655404e4ac50497bbd5e11 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 6.0E-32 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HW35_11700 c9e5d4d15e655404e4ac50497bbd5e11 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 22.055 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HW35_11295 fc9bdbf0ef9e644c164ad6c5ceb1ac1b 183 Pfam PF01965 DJ-1/PfpI family 3 179 4.4E-39 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 HW35_11295 fc9bdbf0ef9e644c164ad6c5ceb1ac1b 183 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 182 9.8E-43 T 12-10-2018 IPR006286 Deglycase PfpI HW35_11295 fc9bdbf0ef9e644c164ad6c5ceb1ac1b 183 Gene3D G3DSA:3.40.50.880 1 183 6.3E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_11295 fc9bdbf0ef9e644c164ad6c5ceb1ac1b 183 SUPERFAMILY SSF52317 1 181 2.07E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_10220 5fb9d6f6e8986b5601a12ecf8f007ba1 292 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 52 79 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 HW35_10220 5fb9d6f6e8986b5601a12ecf8f007ba1 292 Gene3D G3DSA:3.40.50.150 2 216 5.1E-74 T 12-10-2018 HW35_10220 5fb9d6f6e8986b5601a12ecf8f007ba1 292 Gene3D G3DSA:1.10.8.100 220 289 2.3E-21 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 HW35_10220 5fb9d6f6e8986b5601a12ecf8f007ba1 292 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 20 288 56.454 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 HW35_10220 5fb9d6f6e8986b5601a12ecf8f007ba1 292 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 20 286 1.2E-85 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 HW35_10220 5fb9d6f6e8986b5601a12ecf8f007ba1 292 SMART SM00650 36 212 2.1E-83 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 HW35_10220 5fb9d6f6e8986b5601a12ecf8f007ba1 292 Pfam PF00398 Ribosomal RNA adenine dimethylase 20 255 5.2E-74 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm HW35_10220 5fb9d6f6e8986b5601a12ecf8f007ba1 292 SUPERFAMILY SSF53335 17 290 4.18E-75 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_13440 b1971949e2dbac20640faccced82f9a5 471 PIRSF PIRSF006060 7 470 5.1E-93 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HW35_13440 b1971949e2dbac20640faccced82f9a5 471 Gene3D G3DSA:1.20.1740.10 22 470 1.7E-133 T 12-10-2018 HW35_13440 b1971949e2dbac20640faccced82f9a5 471 Pfam PF13520 Amino acid permease 27 445 2.1E-58 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HW35_09040 58b0d23fed8dac880ce85beba8dd74f8 104 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 4 104 20.101 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 HW35_09040 58b0d23fed8dac880ce85beba8dd74f8 104 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 99 2.9E-25 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 378 40.954 T 12-10-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 PRINTS PR00084 Mannitol dehydrogenase signature 115 128 3.6E-19 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 PRINTS PR00084 Mannitol dehydrogenase signature 151 164 3.6E-19 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 3.6E-19 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 PRINTS PR00084 Mannitol dehydrogenase signature 169 184 3.6E-19 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 SUPERFAMILY SSF48179 204 381 3.33E-41 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 Gene3D G3DSA:1.10.1040.10 206 382 8.8E-61 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 SUPERFAMILY SSF51735 3 201 5.26E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 151 365 4.5E-55 T 12-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 Gene3D G3DSA:3.40.50.720 2 204 3.5E-75 T 12-10-2018 HW35_11265 57214016cdfeca40edc2f6f80705be2d 385 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 2 124 3.7E-28 T 12-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_17610 c6c4e6a7deee138e1de952ac7e089ca4 277 Pfam PF00665 Integrase core domain 117 231 4.5E-24 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_17610 c6c4e6a7deee138e1de952ac7e089ca4 277 Pfam PF13276 HTH-like domain 40 93 2.3E-20 T 12-10-2018 IPR025948 HTH-like domain HW35_17610 c6c4e6a7deee138e1de952ac7e089ca4 277 SUPERFAMILY SSF53098 110 275 4.1E-34 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_17610 c6c4e6a7deee138e1de952ac7e089ca4 277 Gene3D G3DSA:3.30.420.10 113 267 4.8E-11 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_13105 4a4a038faa5716a3f19c17fbf7f9fcc5 202 Gene3D G3DSA:3.30.420.10 5 176 6.9E-24 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_13105 4a4a038faa5716a3f19c17fbf7f9fcc5 202 SUPERFAMILY SSF53098 9 175 4.25E-26 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_13105 4a4a038faa5716a3f19c17fbf7f9fcc5 202 Pfam PF00929 Exonuclease 10 169 3.6E-11 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HW35_13105 4a4a038faa5716a3f19c17fbf7f9fcc5 202 SMART SM00479 7 178 6.1E-8 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HW35_05865 04f45331a00621894770fd778654e497 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 2.8E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_05865 04f45331a00621894770fd778654e497 210 SUPERFAMILY SSF48498 82 171 6.99E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily HW35_05865 04f45331a00621894770fd778654e497 210 SUPERFAMILY SSF46689 3 73 7.18E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_05865 04f45331a00621894770fd778654e497 210 Gene3D G3DSA:1.10.357.10 1 195 1.5E-34 T 12-10-2018 HW35_05865 04f45331a00621894770fd778654e497 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_05865 04f45331a00621894770fd778654e497 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 2.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_05045 e2fd9f97840dc1d3b721cce8abe9d421 113 Pfam PF04327 Cysteine protease Prp 1 104 1.0E-27 T 12-10-2018 IPR007422 Cysteine protease Prp HW35_05045 e2fd9f97840dc1d3b721cce8abe9d421 113 SUPERFAMILY SSF118010 1 108 2.35E-34 T 12-10-2018 IPR036764 Cysteine protease Prp superfamily HW35_05045 e2fd9f97840dc1d3b721cce8abe9d421 113 Gene3D G3DSA:3.30.70.1490 1 111 8.7E-36 T 12-10-2018 IPR036764 Cysteine protease Prp superfamily HW35_10830 7daf4c47f7f7eb87b15e0b26d32f1de9 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 1.0E-8 T 12-10-2018 HW35_10830 7daf4c47f7f7eb87b15e0b26d32f1de9 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.2E-24 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10830 7daf4c47f7f7eb87b15e0b26d32f1de9 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10830 7daf4c47f7f7eb87b15e0b26d32f1de9 37 SUPERFAMILY SSF57840 1 37 6.41E-17 T 12-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10830 7daf4c47f7f7eb87b15e0b26d32f1de9 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.778 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10830 7daf4c47f7f7eb87b15e0b26d32f1de9 37 Pfam PF00444 Ribosomal protein L36 1 37 5.7E-19 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 579 1.3E-41 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 Pfam PF00890 FAD binding domain 6 392 8.0E-86 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 PIRSF PIRSF000171 2 240 1.4E-18 T 12-10-2018 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 PIRSF PIRSF000171 336 575 7.4E-14 T 12-10-2018 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 12-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.2E-9 T 12-10-2018 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 7.2E-9 T 12-10-2018 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 Gene3D G3DSA:3.50.50.60 6 403 1.7E-123 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 Gene3D G3DSA:1.20.58.100 423 539 6.8E-33 T 12-10-2018 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 Gene3D G3DSA:3.90.700.10 258 367 1.7E-123 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 579 3.8E-282 T 12-10-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.0E-5 T 12-10-2018 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 3.0E-5 T 12-10-2018 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 SUPERFAMILY SSF46977 443 579 1.1E-44 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 SUPERFAMILY SSF51905 6 426 1.3E-64 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_05420 b2f8897ea3ea40617fe5207e9f101ccd 585 SUPERFAMILY SSF56425 231 353 5.08E-31 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_14835 001672a7cca11763ccbb532623653cff 367 Pfam PF14398 YheC/D like ATP-grasp 98 349 9.3E-68 T 12-10-2018 IPR026838 Endospore coat-associated protein YheC/D HW35_14835 001672a7cca11763ccbb532623653cff 367 Gene3D G3DSA:3.30.470.20 216 341 1.5E-5 T 12-10-2018 HW35_14835 001672a7cca11763ccbb532623653cff 367 SUPERFAMILY SSF56059 116 330 6.28E-15 T 12-10-2018 HW35_15180 d12152977e4820b6519120b71bcfbabd 102 SUPERFAMILY SSF117916 3 100 3.04E-34 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily HW35_15180 d12152977e4820b6519120b71bcfbabd 102 Pfam PF01883 Iron-sulfur cluster assembly protein 6 80 2.4E-23 T 12-10-2018 IPR002744 MIP18 family-like HW35_15180 d12152977e4820b6519120b71bcfbabd 102 Gene3D G3DSA:3.30.300.130 1 102 4.9E-39 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily HW35_13990 4925b97edc7baab3832b5e81b8872665 366 Gene3D G3DSA:3.90.1200.10 127 356 2.4E-62 T 12-10-2018 HW35_13990 4925b97edc7baab3832b5e81b8872665 366 Gene3D G3DSA:3.30.200.20 11 121 5.7E-30 T 12-10-2018 HW35_13990 4925b97edc7baab3832b5e81b8872665 366 Pfam PF01636 Phosphotransferase enzyme family 58 288 4.5E-5 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase HW35_13990 4925b97edc7baab3832b5e81b8872665 366 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 42 356 1.2E-100 T 12-10-2018 IPR014255 Spore coat protein CotS HW35_13990 4925b97edc7baab3832b5e81b8872665 366 SUPERFAMILY SSF56112 25 318 2.04E-30 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_02835 2f1f12c5b5d934acb5966ab0f6078293 64 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 49 2.2E-19 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HW35_02835 2f1f12c5b5d934acb5966ab0f6078293 64 Pfam PF02416 mttA/Hcf106 family 5 57 3.7E-21 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 HW35_02835 2f1f12c5b5d934acb5966ab0f6078293 64 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 61 17.28 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HW35_02835 2f1f12c5b5d934acb5966ab0f6078293 64 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 9.2E-7 T 12-10-2018 HW35_02835 2f1f12c5b5d934acb5966ab0f6078293 64 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 9.2E-7 T 12-10-2018 HW35_02835 2f1f12c5b5d934acb5966ab0f6078293 64 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 9.2E-7 T 12-10-2018 HW35_00855 21500dfbe0790a8a40d407b0278df799 555 SMART SM00642 13 413 2.8E-171 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_00855 21500dfbe0790a8a40d407b0278df799 555 Gene3D G3DSA:2.60.40.1180 475 555 3.3E-23 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta HW35_00855 21500dfbe0790a8a40d407b0278df799 555 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 5 551 6.8E-276 T 12-10-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 HW35_00855 21500dfbe0790a8a40d407b0278df799 555 Gene3D G3DSA:3.20.20.80 168 474 4.9E-126 T 12-10-2018 HW35_00855 21500dfbe0790a8a40d407b0278df799 555 Pfam PF00128 Alpha amylase, catalytic domain 28 371 5.5E-133 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HW35_00855 21500dfbe0790a8a40d407b0278df799 555 SUPERFAMILY SSF51011 474 553 9.97E-19 T 12-10-2018 HW35_00855 21500dfbe0790a8a40d407b0278df799 555 SUPERFAMILY SSF51445 4 471 2.11E-163 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_00855 21500dfbe0790a8a40d407b0278df799 555 Gene3D G3DSA:3.90.400.10 108 167 1.7E-30 T 12-10-2018 HW35_00855 21500dfbe0790a8a40d407b0278df799 555 Pfam PF16657 Maltogenic Amylase, C-terminal domain 474 547 3.6E-7 T 12-10-2018 IPR032091 Maltogenic Amylase, C-terminal HW35_00855 21500dfbe0790a8a40d407b0278df799 555 Gene3D G3DSA:3.20.20.80 1 107 2.9E-51 T 12-10-2018 HW35_17685 5947688a5e1f6a9afd5b8857bbb26ee5 562 Pfam PF13556 PucR C-terminal helix-turn-helix domain 499 556 6.8E-20 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain HW35_17685 5947688a5e1f6a9afd5b8857bbb26ee5 562 SUPERFAMILY SSF46689 505 533 4.48E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_17685 5947688a5e1f6a9afd5b8857bbb26ee5 562 Gene3D G3DSA:1.10.10.2840 429 561 1.6E-21 T 12-10-2018 HW35_17685 5947688a5e1f6a9afd5b8857bbb26ee5 562 Pfam PF07905 Purine catabolism regulatory protein-like family 7 125 2.1E-29 T 12-10-2018 IPR012914 Purine catabolism PurC-like domain HW35_01855 5d458becb4744b998bdf82ceeea11245 223 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 4 219 9.0E-43 T 12-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 HW35_01855 5d458becb4744b998bdf82ceeea11245 223 Pfam PF01902 Diphthamide synthase 4 216 1.2E-42 T 12-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 HW35_01855 5d458becb4744b998bdf82ceeea11245 223 Gene3D G3DSA:3.90.1490.10 129 222 1.0E-20 T 12-10-2018 HW35_01855 5d458becb4744b998bdf82ceeea11245 223 Gene3D G3DSA:3.40.50.620 1 126 1.5E-27 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_01855 5d458becb4744b998bdf82ceeea11245 223 SUPERFAMILY SSF52402 2 220 4.19E-57 T 12-10-2018 HW35_10145 273a259e41696bb2d74483cf5dc4399e 477 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 370 462 7.5E-11 T 12-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 HW35_10145 273a259e41696bb2d74483cf5dc4399e 477 SUPERFAMILY SSF55904 332 474 3.01E-23 T 12-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 HW35_10145 273a259e41696bb2d74483cf5dc4399e 477 SUPERFAMILY SSF53383 8 355 4.65E-85 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_10145 273a259e41696bb2d74483cf5dc4399e 477 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 8 305 1.5E-78 T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 HW35_10145 273a259e41696bb2d74483cf5dc4399e 477 Gene3D G3DSA:3.90.105.10 412 466 2.1E-19 T 12-10-2018 HW35_10145 273a259e41696bb2d74483cf5dc4399e 477 Gene3D G3DSA:3.90.1150.150 278 368 3.9E-114 T 12-10-2018 HW35_10145 273a259e41696bb2d74483cf5dc4399e 477 Gene3D G3DSA:3.40.640.10 47 277 3.9E-114 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_03340 cf75b89ad6ff0193f9c98e11f3045576 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 36.249 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HW35_03340 cf75b89ad6ff0193f9c98e11f3045576 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 370 2.9E-129 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HW35_03340 cf75b89ad6ff0193f9c98e11f3045576 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HW35_03340 cf75b89ad6ff0193f9c98e11f3045576 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HW35_03340 cf75b89ad6ff0193f9c98e11f3045576 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HW35_03340 cf75b89ad6ff0193f9c98e11f3045576 390 SUPERFAMILY SSF103263 1 389 2.35E-147 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HW35_03340 cf75b89ad6ff0193f9c98e11f3045576 390 PIRSF PIRSF001456 1 383 4.7E-130 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HW35_03340 cf75b89ad6ff0193f9c98e11f3045576 390 Pfam PF01264 Chorismate synthase 1 364 7.1E-124 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HW35_03340 cf75b89ad6ff0193f9c98e11f3045576 390 Gene3D G3DSA:3.60.150.10 1 390 1.4E-153 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HW35_14175 a98c1ef3f87172a9a096e97d3413d8e5 223 Gene3D G3DSA:3.40.630.30 9 223 3.0E-56 T 12-10-2018 HW35_14175 a98c1ef3f87172a9a096e97d3413d8e5 223 Pfam PF00583 Acetyltransferase (GNAT) family 28 148 4.5E-13 T 12-10-2018 IPR000182 GNAT domain HW35_14175 a98c1ef3f87172a9a096e97d3413d8e5 223 SUPERFAMILY SSF55729 19 148 1.05E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_07185 62033cb468e04feb64115daf5874c6db 351 Pfam PF01032 FecCD transport family 33 347 9.0E-93 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 HW35_07185 62033cb468e04feb64115daf5874c6db 351 SUPERFAMILY SSF81345 18 347 1.31E-82 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_07185 62033cb468e04feb64115daf5874c6db 351 Gene3D G3DSA:1.10.3470.10 18 351 2.3E-97 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_17370 ca39ac7d06d168cfda7aebd419d3af72 170 Pfam PF11553 Protein of unknown function (DUF3231) 2 166 9.4E-45 T 12-10-2018 IPR021617 Protein of unknown function DUF3231 HW35_17370 ca39ac7d06d168cfda7aebd419d3af72 170 Gene3D G3DSA:1.20.1260.10 1 156 7.3E-62 T 12-10-2018 IPR012347 Ferritin-like HW35_03780 e29fb3ea4bc4585f27baf4192976be0b 108 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 103 1.9E-25 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 HW35_03780 e29fb3ea4bc4585f27baf4192976be0b 108 SUPERFAMILY SSF89360 2 104 1.18E-26 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 HW35_03780 e29fb3ea4bc4585f27baf4192976be0b 108 Gene3D G3DSA:2.60.300.12 1 96 3.8E-6 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 HW35_09225 0cce1b38cd892b9a31105c36c49caadc 216 ProSitePatterns PS00958 Transaldolase active site. 81 98 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 HW35_09225 0cce1b38cd892b9a31105c36c49caadc 216 Gene3D G3DSA:3.20.20.70 1 212 2.9E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_09225 0cce1b38cd892b9a31105c36c49caadc 216 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 202 4.4E-57 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 HW35_09225 0cce1b38cd892b9a31105c36c49caadc 216 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 HW35_09225 0cce1b38cd892b9a31105c36c49caadc 216 SUPERFAMILY SSF51569 1 213 4.61E-77 T 12-10-2018 HW35_09225 0cce1b38cd892b9a31105c36c49caadc 216 Hamap MF_00494 Probable transaldolase [tal]. 1 215 47.057 T 12-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HW35_09225 0cce1b38cd892b9a31105c36c49caadc 216 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 3.8E-103 T 12-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HW35_08265 e0564603dc5f86868b0e107d86bd0287 246 Hamap MF_01240 UPF0309 protein . 1 243 43.121 T 12-10-2018 IPR022951 Uncharacterised protein family UPF0309 HW35_08265 e0564603dc5f86868b0e107d86bd0287 246 SUPERFAMILY SSF53697 4 199 3.03E-24 T 12-10-2018 HW35_08265 e0564603dc5f86868b0e107d86bd0287 246 Gene3D G3DSA:3.40.50.10490 1 238 3.1E-86 T 12-10-2018 HW35_08265 e0564603dc5f86868b0e107d86bd0287 246 Pfam PF13580 SIS domain 4 139 6.4E-41 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HW35_08495 3209030c9c366699bba3f93ba7efd7f0 181 Pfam PF13302 Acetyltransferase (GNAT) domain 12 149 2.9E-26 T 12-10-2018 IPR000182 GNAT domain HW35_08495 3209030c9c366699bba3f93ba7efd7f0 181 SUPERFAMILY SSF55729 6 174 3.01E-48 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_08495 3209030c9c366699bba3f93ba7efd7f0 181 Gene3D G3DSA:3.40.630.30 3 175 1.0E-52 T 12-10-2018 HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 SUPERFAMILY SSF51735 2 146 5.2E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 Gene3D G3DSA:3.40.50.720 1 146 2.1E-46 T 12-10-2018 HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 379 46.909 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 128 3.4E-39 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 Gene3D G3DSA:1.10.1740.10 299 380 2.2E-28 T 12-10-2018 HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 376 4.9E-164 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 SUPERFAMILY SSF69055 289 379 1.57E-31 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 142 225 6.4E-43 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 SUPERFAMILY SSF55347 122 260 6.54E-61 T 12-10-2018 HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 Pfam PF13288 DXP reductoisomerase C-terminal domain 257 374 9.4E-44 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 HW35_16795 6c1e996566cd10922ccb91dc464b9f40 380 PIRSF PIRSF006205 1 380 9.6E-161 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 HW35_07635 6d2dbe151b0717a8cffb33cb856c4470 253 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 253 1.2E-120 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 HW35_07635 6d2dbe151b0717a8cffb33cb856c4470 253 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 253 49.105 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 HW35_07635 6d2dbe151b0717a8cffb33cb856c4470 253 Pfam PF00977 Histidine biosynthesis protein 6 236 5.3E-89 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 HW35_07635 6d2dbe151b0717a8cffb33cb856c4470 253 Gene3D G3DSA:3.20.20.70 1 253 3.9E-109 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_07635 6d2dbe151b0717a8cffb33cb856c4470 253 SUPERFAMILY SSF51366 3 253 1.26E-82 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HW35_15560 5015486a25d389b9f543e94545d4460c 64 SMART SM00914 24 60 4.3E-8 T 12-10-2018 IPR014957 IDEAL domain HW35_15560 5015486a25d389b9f543e94545d4460c 64 Pfam PF08858 IDEAL domain 24 60 1.2E-13 T 12-10-2018 IPR014957 IDEAL domain HW35_15560 5015486a25d389b9f543e94545d4460c 64 Gene3D G3DSA:4.10.810.10 12 64 5.5E-18 T 12-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 HW35_00895 51b360c252b7eb347e11460434eb9c40 337 SUPERFAMILY SSF141986 172 328 7.98E-31 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily HW35_00895 51b360c252b7eb347e11460434eb9c40 337 Gene3D G3DSA:3.40.50.10740 1 158 7.5E-35 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal HW35_00895 51b360c252b7eb347e11460434eb9c40 337 PIRSF PIRSF028757 1 337 8.7E-68 T 12-10-2018 IPR003507 Peptidase family S66 HW35_00895 51b360c252b7eb347e11460434eb9c40 337 SUPERFAMILY SSF52317 1 161 1.97E-38 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_00895 51b360c252b7eb347e11460434eb9c40 337 Gene3D G3DSA:3.50.30.60 159 337 3.2E-37 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily HW35_00895 51b360c252b7eb347e11460434eb9c40 337 Pfam PF02016 LD-carboxypeptidase 13 323 1.5E-69 T 12-10-2018 IPR003507 Peptidase family S66 HW35_11270 0c47d4f85fca0b49d6427314ecc870dd 158 Pfam PF11188 Protein of unknown function (DUF2975) 36 158 5.8E-35 T 12-10-2018 IPR021354 Protein of unknown function DUF2975 HW35_00150 7b87dd3c2939e27e7656a42a2219c865 699 Gene3D G3DSA:3.40.710.10 268 620 2.2E-133 T 12-10-2018 HW35_00150 7b87dd3c2939e27e7656a42a2219c865 699 Pfam PF00912 Transglycosylase 75 241 6.1E-65 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_00150 7b87dd3c2939e27e7656a42a2219c865 699 Gene3D G3DSA:1.10.3810.10 59 257 3.1E-79 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_00150 7b87dd3c2939e27e7656a42a2219c865 699 SUPERFAMILY SSF53955 56 261 4.78E-76 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily HW35_00150 7b87dd3c2939e27e7656a42a2219c865 699 Pfam PF00905 Penicillin binding protein transpeptidase domain 338 614 4.2E-43 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HW35_00150 7b87dd3c2939e27e7656a42a2219c865 699 SUPERFAMILY SSF56601 222 626 1.07E-113 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_00150 7b87dd3c2939e27e7656a42a2219c865 699 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 79 616 5.1E-193 T 12-10-2018 HW35_01100 911209f1829b929bd57424a25ebf14bc 398 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 7 397 7.3E-165 T 12-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HW35_01100 911209f1829b929bd57424a25ebf14bc 398 Hamap MF_01689 Ornithine aminotransferase [rocD]. 6 398 67.875 T 12-10-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 HW35_01100 911209f1829b929bd57424a25ebf14bc 398 Gene3D G3DSA:3.40.640.10 60 308 4.2E-154 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_01100 911209f1829b929bd57424a25ebf14bc 398 SUPERFAMILY SSF53383 5 397 7.09E-126 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_01100 911209f1829b929bd57424a25ebf14bc 398 Gene3D G3DSA:3.90.1150.10 25 387 4.2E-154 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_01100 911209f1829b929bd57424a25ebf14bc 398 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 225 262 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_01100 911209f1829b929bd57424a25ebf14bc 398 Pfam PF00202 Aminotransferase class-III 18 397 2.7E-134 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_01100 911209f1829b929bd57424a25ebf14bc 398 PIRSF PIRSF000521 177 398 3.0E-36 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_01100 911209f1829b929bd57424a25ebf14bc 398 PIRSF PIRSF000521 1 161 1.3E-8 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_06080 f06341915ae0195dce519311225a1e37 268 Pfam PF02675 S-adenosylmethionine decarboxylase 39 175 6.8E-31 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HW35_06080 f06341915ae0195dce519311225a1e37 268 Gene3D G3DSA:3.60.90.10 99 187 1.8E-8 T 12-10-2018 HW35_06080 f06341915ae0195dce519311225a1e37 268 PIRSF PIRSF001356 3 268 6.2E-134 T 12-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HW35_06080 f06341915ae0195dce519311225a1e37 268 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 268 153.712 T 12-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HW35_06080 f06341915ae0195dce519311225a1e37 268 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 8 267 2.8E-135 T 12-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HW35_06080 f06341915ae0195dce519311225a1e37 268 SUPERFAMILY SSF56276 48 179 4.32E-24 T 12-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 HW35_05215 733a4de0146976c2f23532f7618ce488 428 Gene3D G3DSA:3.40.640.10 72 319 2.9E-184 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_05215 733a4de0146976c2f23532f7618ce488 428 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 426 5.2E-202 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 HW35_05215 733a4de0146976c2f23532f7618ce488 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_05215 733a4de0146976c2f23532f7618ce488 428 SUPERFAMILY SSF53383 4 425 4.36E-133 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_05215 733a4de0146976c2f23532f7618ce488 428 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 427 105.832 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 HW35_05215 733a4de0146976c2f23532f7618ce488 428 Gene3D G3DSA:3.90.1150.10 10 421 2.9E-184 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_05215 733a4de0146976c2f23532f7618ce488 428 Pfam PF00202 Aminotransferase class-III 35 415 3.2E-78 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 408 453 1.9E-20 T 12-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 172 183 - T 12-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 Pfam PF01189 16S rRNA methyltransferase RsmB/F 97 300 9.5E-54 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 Gene3D G3DSA:3.40.50.150 92 395 2.0E-104 T 12-10-2018 HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 Gene3D G3DSA:3.30.70.3130 2 90 7.2E-35 T 12-10-2018 HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 106 116 2.9E-28 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 77 91 2.9E-28 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 284 301 2.9E-28 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 173 185 2.9E-28 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 223 239 2.9E-28 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 3 91 1.4E-34 T 12-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 SUPERFAMILY SSF53335 3 301 3.35E-68 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 327 388 6.9E-25 T 12-10-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 34 301 2.5E-67 T 12-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 HW35_11975 bfaf23addba45026f26fcb35bfc48ca5 457 Gene3D G3DSA:2.30.130.60 398 454 5.7E-22 T 12-10-2018 HW35_04335 a4f3874d50b301fc3352612f3b8cea6c 109 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 1 107 8.0E-15 T 12-10-2018 IPR020506 Uncharacterised protein family YqfZ HW35_06235 13a33c5307ca3c246dc7e6ff251be15d 307 Pfam PF01497 Periplasmic binding protein 57 282 2.7E-29 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain HW35_06235 13a33c5307ca3c246dc7e6ff251be15d 307 Gene3D G3DSA:3.40.50.1980 139 307 2.8E-62 T 12-10-2018 HW35_06235 13a33c5307ca3c246dc7e6ff251be15d 307 SUPERFAMILY SSF53807 39 300 3.41E-51 T 12-10-2018 HW35_06235 13a33c5307ca3c246dc7e6ff251be15d 307 Gene3D G3DSA:3.40.50.1980 49 138 8.2E-27 T 12-10-2018 HW35_07755 9f0a70b3349656a35f95f9c1b3e50509 313 SUPERFAMILY SSF161098 61 300 2.22E-57 T 12-10-2018 IPR035906 MetI-like superfamily HW35_07755 9f0a70b3349656a35f95f9c1b3e50509 313 Gene3D G3DSA:1.10.3720.10 57 312 4.3E-69 T 12-10-2018 IPR035906 MetI-like superfamily HW35_07755 9f0a70b3349656a35f95f9c1b3e50509 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 306 2.3E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_04585 69dd13e949139ddb3805e2477dc005e3 404 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 79 1.2E-11 T 12-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HW35_04585 69dd13e949139ddb3805e2477dc005e3 404 Pfam PF01610 Transposase 150 390 8.2E-71 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HW35_12160 ba266091177bfa4aa0a54eaac39f46d2 538 Pfam PF05787 Bacterial protein of unknown function (DUF839) 52 513 1.2E-118 T 12-10-2018 IPR008557 Protein of unknown function DUF839 HW35_12160 ba266091177bfa4aa0a54eaac39f46d2 538 SUPERFAMILY SSF101898 253 507 3.4E-10 T 12-10-2018 HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 417 164.448 T 12-10-2018 IPR008135 Competence-induced protein CinA HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 2 411 1.2E-150 T 12-10-2018 IPR008135 Competence-induced protein CinA HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 Pfam PF00994 Probable molybdopterin binding domain 4 166 1.6E-35 T 12-10-2018 IPR001453 MoaB/Mog domain HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 SUPERFAMILY SSF53218 2 206 1.28E-40 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 SUPERFAMILY SSF142433 250 412 1.96E-50 T 12-10-2018 IPR036653 CinA-like, C-terminal HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 PIRSF PIRSF006728 1 416 2.7E-158 T 12-10-2018 IPR008135 Competence-induced protein CinA HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 264 408 1.5E-44 T 12-10-2018 IPR008136 CinA, C-terminal HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 SMART SM00852 4 170 1.3E-42 T 12-10-2018 IPR001453 MoaB/Mog domain HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 Gene3D G3DSA:3.90.950.20 242 411 1.1E-51 T 12-10-2018 IPR036653 CinA-like, C-terminal HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 Pfam PF02464 Competence-damaged protein 262 409 5.9E-51 T 12-10-2018 IPR008136 CinA, C-terminal HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 Gene3D G3DSA:3.40.980.10 1 168 5.4E-52 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily HW35_16985 06df7c807d0a8576b8b149c7cbae54cf 417 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 162 1.3E-30 T 12-10-2018 IPR001453 MoaB/Mog domain HW35_02590 b39dbc10bc9f99939959bcaece03e4cf 250 Gene3D G3DSA:1.10.10.10 1 58 1.3E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_02590 b39dbc10bc9f99939959bcaece03e4cf 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 HW35_02590 b39dbc10bc9f99939959bcaece03e4cf 250 SUPERFAMILY SSF100950 74 228 6.28E-35 T 12-10-2018 IPR037171 NagB/RpiA transferase-like HW35_02590 b39dbc10bc9f99939959bcaece03e4cf 250 SUPERFAMILY SSF46785 5 60 3.62E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_02590 b39dbc10bc9f99939959bcaece03e4cf 250 Pfam PF00455 DeoR C terminal sensor domain 75 228 2.5E-46 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain HW35_02590 b39dbc10bc9f99939959bcaece03e4cf 250 SMART SM00420 6 58 6.6E-21 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HW35_02590 b39dbc10bc9f99939959bcaece03e4cf 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.7E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HW35_02590 b39dbc10bc9f99939959bcaece03e4cf 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.7E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HW35_02590 b39dbc10bc9f99939959bcaece03e4cf 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 2.4E-18 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HW35_02590 b39dbc10bc9f99939959bcaece03e4cf 250 SMART SM01134 73 231 1.8E-63 T 12-10-2018 HW35_06065 2d938b119ca90a4a6a9baa2fe06fca23 250 SMART SM00382 41 217 2.7E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_06065 2d938b119ca90a4a6a9baa2fe06fca23 250 Gene3D G3DSA:3.40.50.300 106 235 6.0E-11 T 12-10-2018 HW35_06065 2d938b119ca90a4a6a9baa2fe06fca23 250 Pfam PF13476 AAA domain 31 76 1.9E-9 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain HW35_06065 2d938b119ca90a4a6a9baa2fe06fca23 250 Gene3D G3DSA:3.40.50.300 27 103 4.5E-10 T 12-10-2018 HW35_06065 2d938b119ca90a4a6a9baa2fe06fca23 250 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 150 205 2.1E-7 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HW35_06065 2d938b119ca90a4a6a9baa2fe06fca23 250 SUPERFAMILY SSF52540 28 221 2.21E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 1.8E-81 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 448 2.1E-244 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 4.9E-44 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 SUPERFAMILY SSF56059 83 350 6.01E-73 T 12-10-2018 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.4E-48 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 SMART SM00878 337 443 1.2E-70 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 Gene3D G3DSA:3.30.470.20 87 443 6.6E-159 T 12-10-2018 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 Gene3D G3DSA:3.30.1490.20 131 202 6.6E-159 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 Gene3D G3DSA:3.40.50.20 2 85 3.8E-40 T 12-10-2018 HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 SUPERFAMILY SSF52440 1 113 6.69E-53 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HW35_03990 27ff5a2356fb579af30b90ead5f07fe4 451 SUPERFAMILY SSF51246 332 443 1.1E-46 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 HW35_09240 46cfc0287b0ffa7ffc89ccefb50df08d 175 SUPERFAMILY SSF53697 10 158 1.22E-8 T 12-10-2018 HW35_09240 46cfc0287b0ffa7ffc89ccefb50df08d 175 Pfam PF10740 Domain of unknown function (DUF2529) 1 171 2.1E-66 T 12-10-2018 IPR019676 Domain of unknown function (DUF2529) HW35_09240 46cfc0287b0ffa7ffc89ccefb50df08d 175 Gene3D G3DSA:3.40.50.10490 1 175 4.7E-61 T 12-10-2018 HW35_01720 6ad54960a0e375fafd8da40bb43f4a66 147 Gene3D G3DSA:3.10.400.10 1 146 1.3E-53 T 12-10-2018 HW35_01720 6ad54960a0e375fafd8da40bb43f4a66 147 SUPERFAMILY SSF88697 1 147 9.44E-48 T 12-10-2018 IPR015947 PUA-like superfamily HW35_01720 6ad54960a0e375fafd8da40bb43f4a66 147 Pfam PF04266 ASCH domain 36 145 1.5E-26 T 12-10-2018 IPR007374 ASCH domain HW35_01720 6ad54960a0e375fafd8da40bb43f4a66 147 SMART SM01022 29 145 3.8E-38 T 12-10-2018 IPR007374 ASCH domain HW35_01720 6ad54960a0e375fafd8da40bb43f4a66 147 PIRSF PIRSF021320 1 147 3.2E-49 T 12-10-2018 IPR009326 Protein of unknown function DUF984 HW35_11610 317e5387c4443d2fcc4820d6daff79af 352 Gene3D G3DSA:2.70.98.10 8 350 9.0E-115 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 HW35_11610 317e5387c4443d2fcc4820d6daff79af 352 Pfam PF01263 Aldose 1-epimerase 18 345 4.2E-84 T 12-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 HW35_11610 317e5387c4443d2fcc4820d6daff79af 352 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 175 184 - T 12-10-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 HW35_11610 317e5387c4443d2fcc4820d6daff79af 352 PIRSF PIRSF005096 2 349 3.1E-126 T 12-10-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 HW35_11610 317e5387c4443d2fcc4820d6daff79af 352 SUPERFAMILY SSF74650 5 346 1.51E-106 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 HW35_06960 6d4316ca4cdb3c18d1d5939a1932b9ce 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 288 2.8E-67 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HW35_06960 6d4316ca4cdb3c18d1d5939a1932b9ce 331 Gene3D G3DSA:3.40.50.720 99 288 4.8E-127 T 12-10-2018 HW35_06960 6d4316ca4cdb3c18d1d5939a1932b9ce 331 SUPERFAMILY SSF52283 2 136 5.86E-35 T 12-10-2018 HW35_06960 6d4316ca4cdb3c18d1d5939a1932b9ce 331 SUPERFAMILY SSF51735 102 289 4.22E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_06960 6d4316ca4cdb3c18d1d5939a1932b9ce 331 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 150 177 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 HW35_06960 6d4316ca4cdb3c18d1d5939a1932b9ce 331 Gene3D G3DSA:3.40.50.720 5 314 4.8E-127 T 12-10-2018 HW35_06960 6d4316ca4cdb3c18d1d5939a1932b9ce 331 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 227 243 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site HW35_06960 6d4316ca4cdb3c18d1d5939a1932b9ce 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 320 2.0E-32 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 HW35_10365 c20523b71380fb74ee63b73168528204 255 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 249 3.9E-86 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 HW35_10365 c20523b71380fb74ee63b73168528204 255 SUPERFAMILY SSF53067 2 122 3.45E-39 T 12-10-2018 HW35_10365 c20523b71380fb74ee63b73168528204 255 Pfam PF03309 Type III pantothenate kinase 3 206 1.7E-75 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 HW35_10365 c20523b71380fb74ee63b73168528204 255 Gene3D G3DSA:3.30.420.40 89 255 3.3E-63 T 12-10-2018 HW35_10365 c20523b71380fb74ee63b73168528204 255 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 37.486 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 HW35_10365 c20523b71380fb74ee63b73168528204 255 Gene3D G3DSA:3.30.420.40 1 88 2.2E-33 T 12-10-2018 HW35_10365 c20523b71380fb74ee63b73168528204 255 SUPERFAMILY SSF53067 124 253 2.51E-40 T 12-10-2018 HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 SUPERFAMILY SSF47413 1 59 1.21E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 Pfam PF13377 Periplasmic binding protein-like domain 170 331 2.7E-42 T 12-10-2018 HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 Gene3D G3DSA:3.40.50.2300 162 291 1.5E-85 T 12-10-2018 HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.1E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 SMART SM00354 1 71 2.3E-29 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 Gene3D G3DSA:1.10.260.40 3 59 3.6E-21 T 12-10-2018 HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 Gene3D G3DSA:3.40.50.2300 63 309 1.5E-85 T 12-10-2018 HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.2E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.2E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 SUPERFAMILY SSF53822 61 332 3.62E-90 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_01835 dad9149bc49311d8fceafe22f1cdcd72 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 HW35_00845 0ac9f1bddd3c904c4b0eab5b7cb471be 260 PRINTS PR01543 Arylamine N-acetyltransferase signature 103 128 1.5E-14 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 HW35_00845 0ac9f1bddd3c904c4b0eab5b7cb471be 260 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 1.5E-14 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 HW35_00845 0ac9f1bddd3c904c4b0eab5b7cb471be 260 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 1.5E-14 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 HW35_00845 0ac9f1bddd3c904c4b0eab5b7cb471be 260 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 1.5E-14 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 HW35_00845 0ac9f1bddd3c904c4b0eab5b7cb471be 260 Gene3D G3DSA:3.30.2140.20 1 260 9.5E-76 T 12-10-2018 HW35_00845 0ac9f1bddd3c904c4b0eab5b7cb471be 260 Pfam PF00797 N-acetyltransferase 22 260 1.1E-44 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 HW35_00845 0ac9f1bddd3c904c4b0eab5b7cb471be 260 SUPERFAMILY SSF54001 10 259 4.41E-55 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily HW35_04895 7bf724732c559d09dc57533f2192a7ef 148 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 1.1E-58 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 HW35_04895 7bf724732c559d09dc57533f2192a7ef 148 Gene3D G3DSA:3.50.80.10 1 148 9.8E-61 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily HW35_04895 7bf724732c559d09dc57533f2192a7ef 148 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 1.1E-60 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 HW35_04895 7bf724732c559d09dc57533f2192a7ef 148 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.041 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 HW35_04895 7bf724732c559d09dc57533f2192a7ef 148 SUPERFAMILY SSF69500 1 144 2.35E-59 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily HW35_09445 1ade97bbad67b3c7bab078e1827eaa74 278 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 2.1E-87 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 HW35_09445 1ade97bbad67b3c7bab078e1827eaa74 278 SUPERFAMILY SSF53613 1 263 8.26E-73 T 12-10-2018 IPR029056 Ribokinase-like HW35_09445 1ade97bbad67b3c7bab078e1827eaa74 278 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 1.2E-78 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_09445 1ade97bbad67b3c7bab078e1827eaa74 278 Gene3D G3DSA:3.40.1190.20 2 276 9.7E-89 T 12-10-2018 IPR029056 Ribokinase-like HW35_11540 bc6478c9e11026421457195b269d6882 235 Pfam PF00814 Glycoprotease family 32 148 4.9E-29 T 12-10-2018 IPR000905 Gcp-like domain HW35_11540 bc6478c9e11026421457195b269d6882 235 SUPERFAMILY SSF53067 109 215 1.42E-13 T 12-10-2018 HW35_11540 bc6478c9e11026421457195b269d6882 235 Gene3D G3DSA:3.30.420.40 95 190 1.5E-48 T 12-10-2018 HW35_11540 bc6478c9e11026421457195b269d6882 235 SUPERFAMILY SSF53067 1 100 5.61E-27 T 12-10-2018 HW35_11540 bc6478c9e11026421457195b269d6882 235 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 217 1.3E-53 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 HW35_11540 bc6478c9e11026421457195b269d6882 235 Gene3D G3DSA:3.30.420.40 3 217 1.5E-48 T 12-10-2018 HW35_06945 e79f4e8d454be93c634feee633b1cebe 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 1.5E-7 T 12-10-2018 HW35_06945 e79f4e8d454be93c634feee633b1cebe 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 1.5E-7 T 12-10-2018 HW35_06945 e79f4e8d454be93c634feee633b1cebe 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 1.5E-7 T 12-10-2018 HW35_06945 e79f4e8d454be93c634feee633b1cebe 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.5E-7 T 12-10-2018 HW35_06945 e79f4e8d454be93c634feee633b1cebe 356 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 285 4.7E-36 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_06945 e79f4e8d454be93c634feee633b1cebe 356 Gene3D G3DSA:3.50.50.100 1 355 3.6E-75 T 12-10-2018 HW35_06945 e79f4e8d454be93c634feee633b1cebe 356 SUPERFAMILY SSF51905 1 306 1.3E-23 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_06945 e79f4e8d454be93c634feee633b1cebe 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 1.6E-5 T 12-10-2018 HW35_06945 e79f4e8d454be93c634feee633b1cebe 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.6E-5 T 12-10-2018 HW35_06945 e79f4e8d454be93c634feee633b1cebe 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 274 1.6E-5 T 12-10-2018 HW35_00170 5a5a48cf54b5b7c1c7763f3c460b3c62 404 Gene3D G3DSA:3.30.300.210 244 395 2.9E-37 T 12-10-2018 IPR038501 Spore germination GerAC superfamily HW35_00170 5a5a48cf54b5b7c1c7763f3c460b3c62 404 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 228 392 1.5E-38 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HW35_00170 5a5a48cf54b5b7c1c7763f3c460b3c62 404 Gene3D G3DSA:3.10.450.290 26 91 2.6E-6 T 12-10-2018 HW35_00170 5a5a48cf54b5b7c1c7763f3c460b3c62 404 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 394 7.0E-92 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HW35_14735 726b013726c8cf90cf50a667548e5053 419 Pfam PF08388 Group II intron, maturase-specific domain 287 359 1.7E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_14735 726b013726c8cf90cf50a667548e5053 419 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 352 4.9E-131 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_14735 726b013726c8cf90cf50a667548e5053 419 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 271 1.5E-45 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_14735 726b013726c8cf90cf50a667548e5053 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 186 199 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_14735 726b013726c8cf90cf50a667548e5053 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_14735 726b013726c8cf90cf50a667548e5053 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_14735 726b013726c8cf90cf50a667548e5053 419 SUPERFAMILY SSF56672 16 345 4.95E-59 T 12-10-2018 HW35_09760 3c39f62f9a757b7519d6698fdfb5c45a 392 SUPERFAMILY SSF116734 203 391 1.08E-33 T 12-10-2018 HW35_09760 3c39f62f9a757b7519d6698fdfb5c45a 392 Gene3D G3DSA:3.90.220.20 7 149 1.7E-92 T 12-10-2018 HW35_09760 3c39f62f9a757b7519d6698fdfb5c45a 392 SUPERFAMILY SSF116734 7 197 1.64E-48 T 12-10-2018 HW35_09760 3c39f62f9a757b7519d6698fdfb5c45a 392 Pfam PF01420 Type I restriction modification DNA specificity domain 4 182 5.0E-40 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HW35_09760 3c39f62f9a757b7519d6698fdfb5c45a 392 Pfam PF01420 Type I restriction modification DNA specificity domain 206 355 1.4E-27 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HW35_09760 3c39f62f9a757b7519d6698fdfb5c45a 392 Gene3D G3DSA:3.90.220.20 208 351 1.7E-92 T 12-10-2018 HW35_09760 3c39f62f9a757b7519d6698fdfb5c45a 392 Gene3D G3DSA:1.10.287.1120 150 391 1.7E-92 T 12-10-2018 HW35_02430 9a929aa1c90c48d5ce26a0640b5eea8c 501 SMART SM00091 383 449 5.7E-9 T 12-10-2018 IPR000014 PAS domain HW35_02430 9a929aa1c90c48d5ce26a0640b5eea8c 501 Pfam PF07690 Major Facilitator Superfamily 17 340 5.5E-48 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_02430 9a929aa1c90c48d5ce26a0640b5eea8c 501 SUPERFAMILY SSF103473 14 379 1.96E-64 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_02430 9a929aa1c90c48d5ce26a0640b5eea8c 501 Pfam PF13426 PAS domain 394 491 1.8E-13 T 12-10-2018 IPR000014 PAS domain HW35_02430 9a929aa1c90c48d5ce26a0640b5eea8c 501 Gene3D G3DSA:3.30.450.20 380 499 2.2E-30 T 12-10-2018 HW35_02430 9a929aa1c90c48d5ce26a0640b5eea8c 501 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 380 491 9.8E-16 T 12-10-2018 IPR000014 PAS domain HW35_02430 9a929aa1c90c48d5ce26a0640b5eea8c 501 Gene3D G3DSA:1.20.1250.20 2 379 2.8E-89 T 12-10-2018 HW35_02430 9a929aa1c90c48d5ce26a0640b5eea8c 501 SUPERFAMILY SSF55785 392 491 9.25E-27 T 12-10-2018 IPR035965 PAS domain superfamily HW35_03350 f73b395468554576f9ce366a2a941381 320 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 320 3.4E-159 T 12-10-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 HW35_03350 f73b395468554576f9ce366a2a941381 320 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site HW35_03350 f73b395468554576f9ce366a2a941381 320 SUPERFAMILY SSF48576 7 319 3.06E-85 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily HW35_03350 f73b395468554576f9ce366a2a941381 320 Gene3D G3DSA:1.10.600.10 7 320 6.7E-101 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily HW35_03350 f73b395468554576f9ce366a2a941381 320 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site HW35_03350 f73b395468554576f9ce366a2a941381 320 Pfam PF00348 Polyprenyl synthetase 31 270 5.3E-69 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 HW35_01005 86fe1025ae7fc0541c038ca343c97069 142 PIRSF PIRSF003230 3 140 1.5E-31 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 HW35_01005 86fe1025ae7fc0541c038ca343c97069 142 SUPERFAMILY SSF54637 6 136 9.64E-37 T 12-10-2018 IPR029069 HotDog domain superfamily HW35_01005 86fe1025ae7fc0541c038ca343c97069 142 Pfam PF13279 Thioesterase-like superfamily 17 133 2.3E-10 T 12-10-2018 HW35_01005 86fe1025ae7fc0541c038ca343c97069 142 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 13 125 3.8E-30 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 HW35_01005 86fe1025ae7fc0541c038ca343c97069 142 Gene3D G3DSA:3.10.129.10 3 141 5.9E-33 T 12-10-2018 HW35_09785 05a40ee37b5ab30c929f38a3cf127f7f 264 SMART SM00849 13 218 6.3E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_09785 05a40ee37b5ab30c929f38a3cf127f7f 264 Pfam PF12706 Beta-lactamase superfamily domain 24 218 2.6E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_09785 05a40ee37b5ab30c929f38a3cf127f7f 264 SUPERFAMILY SSF56281 8 230 9.43E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_09785 05a40ee37b5ab30c929f38a3cf127f7f 264 Gene3D G3DSA:3.60.15.10 9 249 1.0E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_10985 f29817ea6c175b12698f79f7cc2111cb 250 Pfam PF01522 Polysaccharide deacetylase 51 172 1.0E-25 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HW35_10985 f29817ea6c175b12698f79f7cc2111cb 250 Gene3D G3DSA:3.20.20.370 49 250 2.9E-59 T 12-10-2018 HW35_10985 f29817ea6c175b12698f79f7cc2111cb 250 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 53 239 2.6E-79 T 12-10-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB HW35_10985 f29817ea6c175b12698f79f7cc2111cb 250 SUPERFAMILY SSF88713 27 239 5.19E-51 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HW35_15965 5c45e5210d1c43821fad5d1262555a67 490 Gene3D G3DSA:3.90.1150.10 312 407 2.0E-6 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_15965 5c45e5210d1c43821fad5d1262555a67 490 Gene3D G3DSA:3.90.105.10 420 477 2.9E-19 T 12-10-2018 HW35_15965 5c45e5210d1c43821fad5d1262555a67 490 SUPERFAMILY SSF53383 6 387 3.68E-101 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_15965 5c45e5210d1c43821fad5d1262555a67 490 Gene3D G3DSA:3.40.640.10 6 282 1.3E-97 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_15965 5c45e5210d1c43821fad5d1262555a67 490 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 403 460 1.3E-10 T 12-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 HW35_15965 5c45e5210d1c43821fad5d1262555a67 490 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 369 3.4E-114 T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 HW35_15965 5c45e5210d1c43821fad5d1262555a67 490 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 221 235 - T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 HW35_01660 45af0f849858ab7ad3a46c140b8a0785 309 Gene3D G3DSA:1.10.260.150 60 309 1.2E-77 T 12-10-2018 HW35_01660 45af0f849858ab7ad3a46c140b8a0785 309 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 81 224 1.9E-33 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HW35_01660 45af0f849858ab7ad3a46c140b8a0785 309 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 82 224 2.6E-45 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HW35_15365 c26e6dd98f4e04b882b207e301fbe633 300 Gene3D G3DSA:1.10.472.60 70 194 3.7E-33 T 12-10-2018 HW35_15365 c26e6dd98f4e04b882b207e301fbe633 300 SUPERFAMILY SSF52833 28 233 3.25E-30 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_15365 c26e6dd98f4e04b882b207e301fbe633 300 Gene3D G3DSA:3.40.30.10 35 225 3.7E-33 T 12-10-2018 HW35_15365 c26e6dd98f4e04b882b207e301fbe633 300 Pfam PF13743 Thioredoxin 33 225 2.2E-77 T 12-10-2018 HW35_17085 cd0bc7f62d3c2269ae3f1d2427c3e33a 203 SUPERFAMILY SSF53474 2 200 7.3E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_17085 cd0bc7f62d3c2269ae3f1d2427c3e33a 203 Pfam PF02230 Phospholipase/Carboxylesterase 7 200 5.5E-9 T 12-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 HW35_17085 cd0bc7f62d3c2269ae3f1d2427c3e33a 203 Gene3D G3DSA:3.40.50.1820 1 200 2.5E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_04975 56370bea5ae4628a15dad46b69bc971a 178 Gene3D G3DSA:3.10.20.420 44 98 5.2E-22 T 12-10-2018 IPR038118 Bypass-of-forespore C, N-terminal domain superfamily HW35_04975 56370bea5ae4628a15dad46b69bc971a 178 Gene3D G3DSA:3.30.70.1740 99 175 1.4E-32 T 12-10-2018 IPR038117 Bypass of forespore C, C-terminal domain superfamily HW35_04975 56370bea5ae4628a15dad46b69bc971a 178 Pfam PF08977 Bypass of Forespore C, N terminal 47 97 1.4E-21 T 12-10-2018 IPR015071 Bypass-of-forespore C, N-terminal HW35_04975 56370bea5ae4628a15dad46b69bc971a 178 Pfam PF08955 BofC C-terminal domain 99 171 1.9E-30 T 12-10-2018 IPR015050 Bypass of forespore C, C-terminal HW35_09550 2b1e6ecbb65bfbe33a5dc86478353d20 395 Gene3D G3DSA:1.20.1250.20 4 395 2.9E-89 T 12-10-2018 HW35_09550 2b1e6ecbb65bfbe33a5dc86478353d20 395 ProSitePatterns PS00217 Sugar transport proteins signature 2. 102 127 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HW35_09550 2b1e6ecbb65bfbe33a5dc86478353d20 395 SUPERFAMILY SSF103473 4 394 7.19E-84 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_09550 2b1e6ecbb65bfbe33a5dc86478353d20 395 Pfam PF07690 Major Facilitator Superfamily 15 256 5.9E-38 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_00240 309702225021138c54e8f83b2d8d948f 120 SUPERFAMILY SSF52172 1 119 1.99E-39 T 12-10-2018 IPR011006 CheY-like superfamily HW35_00240 309702225021138c54e8f83b2d8d948f 120 SMART SM00448 2 114 1.8E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_00240 309702225021138c54e8f83b2d8d948f 120 Pfam PF00072 Response regulator receiver domain 4 114 6.0E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_00240 309702225021138c54e8f83b2d8d948f 120 Gene3D G3DSA:3.40.50.2300 1 120 2.5E-39 T 12-10-2018 HW35_04930 43e0e7afab099c1a50bffd74ca53c319 517 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 357 498 6.4E-19 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HW35_04930 43e0e7afab099c1a50bffd74ca53c319 517 PIRSF PIRSF038958 1 515 1.4E-169 T 12-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type HW35_04930 43e0e7afab099c1a50bffd74ca53c319 517 Pfam PF01943 Polysaccharide biosynthesis protein 4 305 7.2E-55 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HW35_04930 43e0e7afab099c1a50bffd74ca53c319 517 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 4 492 1.1E-169 T 12-10-2018 IPR014249 Sporulation stage V protein B HW35_12680 5e92d8025472e5df9a13931828267b3a 427 TIGRFAM TIGR01814 kynureninase: kynureninase 12 411 2.2E-129 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 HW35_12680 5e92d8025472e5df9a13931828267b3a 427 Gene3D G3DSA:3.90.1150.10 15 411 2.7E-152 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_12680 5e92d8025472e5df9a13931828267b3a 427 Pfam PF00266 Aminotransferase class-V 76 376 5.2E-27 T 12-10-2018 IPR000192 Aminotransferase class V domain HW35_12680 5e92d8025472e5df9a13931828267b3a 427 Hamap MF_01970 Kynureninase [kynU]. 1 411 41.217 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 HW35_12680 5e92d8025472e5df9a13931828267b3a 427 SUPERFAMILY SSF53383 8 412 2.89E-85 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_12680 5e92d8025472e5df9a13931828267b3a 427 PIRSF PIRSF038800 5 419 2.1E-162 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 HW35_12680 5e92d8025472e5df9a13931828267b3a 427 Gene3D G3DSA:3.40.640.10 46 315 2.7E-152 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_12970 32073a47a4cfb2308112ba3610f4d3fe 97 Gene3D G3DSA:1.20.90.10 5 94 1.5E-18 T 12-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 HW35_12970 32073a47a4cfb2308112ba3610f4d3fe 97 SUPERFAMILY SSF48619 7 73 5.25E-11 T 12-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 HW35_12970 32073a47a4cfb2308112ba3610f4d3fe 97 ProSitePatterns PS00118 Phospholipase A2 histidine active site. 38 45 - T 12-10-2018 IPR033113 Phospholipase A2, histidine active site KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783|Reactome: R-HSA-1482788|Reactome: R-HSA-1482801|Reactome: R-HSA-1482839|Reactome: R-HSA-1482922|Reactome: R-HSA-1482925|Reactome: R-HSA-1483166 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 SUPERFAMILY SSF46785 5 78 2.31E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_03950 b963101cadb239b0a26e39b5ec196986 149 Gene3D G3DSA:3.30.1360.40 68 149 3.6E-32 T 12-10-2018 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 4.3E-54 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 Pfam PF02863 Arginine repressor, C-terminal domain 82 145 1.8E-27 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 2.0E-21 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 SUPERFAMILY SSF55252 80 149 7.32E-21 T 12-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 1.4E-30 T 12-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 70.326 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 2.5E-27 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.5E-27 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.5E-27 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 2.5E-27 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HW35_03950 b963101cadb239b0a26e39b5ec196986 149 Gene3D G3DSA:1.10.10.10 4 67 3.6E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_17005 cb343a5aefd4d533a7c0cd5d28404548 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 5.0E-32 T 12-10-2018 IPR007347 Sporulation stage V, protein S HW35_17005 cb343a5aefd4d533a7c0cd5d28404548 86 Gene3D G3DSA:3.30.110.20 1 86 3.6E-36 T 12-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 HW35_17005 cb343a5aefd4d533a7c0cd5d28404548 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 4.3E-40 T 12-10-2018 IPR007347 Sporulation stage V, protein S HW35_04290 1896ad4c200215350d222ede7d852772 219 Gene3D G3DSA:1.20.58.220 3 219 1.4E-70 T 12-10-2018 IPR038078 PhoU-like domain superfamily HW35_04290 1896ad4c200215350d222ede7d852772 219 Pfam PF01895 PhoU domain 18 106 2.9E-20 T 12-10-2018 IPR026022 PhoU domain HW35_04290 1896ad4c200215350d222ede7d852772 219 Pfam PF01895 PhoU domain 121 205 3.2E-17 T 12-10-2018 IPR026022 PhoU domain HW35_04290 1896ad4c200215350d222ede7d852772 219 PIRSF PIRSF003107 1 219 1.9E-63 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HW35_04290 1896ad4c200215350d222ede7d852772 219 SUPERFAMILY SSF109755 4 217 3.03E-64 T 12-10-2018 HW35_04290 1896ad4c200215350d222ede7d852772 219 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 214 1.3E-61 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HW35_14880 f8778e0127b72e24155c3a0cc6c0c578 405 PIRSF PIRSF033091 1 405 4.8E-134 T 12-10-2018 IPR014576 Predicted phosphoesterase, YhaO type HW35_14880 f8778e0127b72e24155c3a0cc6c0c578 405 Gene3D G3DSA:3.60.21.10 2 252 4.7E-58 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like HW35_14880 f8778e0127b72e24155c3a0cc6c0c578 405 SUPERFAMILY SSF56300 5 278 1.69E-49 T 12-10-2018 HW35_14880 f8778e0127b72e24155c3a0cc6c0c578 405 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 6 230 3.1E-14 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 HW35_16590 0d2d1111b18a5313856e8ded44e3006a 215 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 146 208 4.4E-18 T 12-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HW35_16590 0d2d1111b18a5313856e8ded44e3006a 215 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 4 211 1.7E-64 T 12-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HW35_16590 0d2d1111b18a5313856e8ded44e3006a 215 SMART SM00983 143 209 6.9E-25 T 12-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HW35_16590 0d2d1111b18a5313856e8ded44e3006a 215 Gene3D G3DSA:3.40.50.10240 1 215 7.7E-79 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HW35_16590 0d2d1111b18a5313856e8ded44e3006a 215 SUPERFAMILY SSF63999 3 123 4.71E-33 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HW35_16590 0d2d1111b18a5313856e8ded44e3006a 215 SUPERFAMILY SSF63862 135 213 2.22E-15 T 12-10-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HW35_16590 0d2d1111b18a5313856e8ded44e3006a 215 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 19 126 5.8E-24 T 12-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HW35_13215 9e67ffceca01f78acb36eb2ea74f023d 76 Pfam PF12728 Helix-turn-helix domain 2 50 2.1E-10 T 12-10-2018 HW35_13215 9e67ffceca01f78acb36eb2ea74f023d 76 Gene3D G3DSA:1.10.1660.40 2 46 1.0E-5 T 12-10-2018 IPR038148 Transposon Tn1545/Tn916, excisionase HW35_13215 9e67ffceca01f78acb36eb2ea74f023d 76 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 2 50 1.2E-15 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 HW35_07910 5bc4efecddee5440bf1b7db763f5d626 212 SUPERFAMILY SSF54211 3 131 4.17E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_07910 5bc4efecddee5440bf1b7db763f5d626 212 Gene3D G3DSA:3.30.230.30 1 133 1.2E-51 T 12-10-2018 IPR036956 Impact, N-terminal domain superfamily HW35_07910 5bc4efecddee5440bf1b7db763f5d626 212 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 12-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site HW35_07910 5bc4efecddee5440bf1b7db763f5d626 212 Pfam PF09186 Domain of unknown function (DUF1949) 140 195 1.6E-17 T 12-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal HW35_07910 5bc4efecddee5440bf1b7db763f5d626 212 Pfam PF01205 Uncharacterized protein family UPF0029 19 123 3.5E-33 T 12-10-2018 IPR001498 Impact, N-terminal HW35_07910 5bc4efecddee5440bf1b7db763f5d626 212 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 202 7.7E-79 T 12-10-2018 IPR015796 Impact family, bacterial/archaeal HW35_07910 5bc4efecddee5440bf1b7db763f5d626 212 SUPERFAMILY SSF54980 135 201 3.17E-12 T 12-10-2018 IPR035647 EF-G domain III/V-like HW35_04030 ad0f823f9a3264b59809c4b49cd20721 67 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 1.1E-16 T 12-10-2018 IPR025664 Stage III sporulation protein AC/AD family HW35_04030 ad0f823f9a3264b59809c4b49cd20721 67 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 3 66 2.3E-30 T 12-10-2018 IPR009570 Stage III sporulation protein AC HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 SUPERFAMILY SSF50104 121 177 4.29E-20 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 1.8E-67 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 SMART SM00738 2 113 4.4E-55 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 Gene3D G3DSA:3.30.70.940 1 118 4.2E-46 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 1.5E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 1.5E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 1.5E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 SUPERFAMILY SSF82679 2 114 1.24E-41 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 29.833 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 Pfam PF00467 KOW motif 128 157 5.4E-5 T 12-10-2018 IPR005824 KOW HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 Gene3D G3DSA:2.30.30.30 119 177 3.1E-26 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 Pfam PF02357 Transcription termination factor nusG 3 109 1.4E-28 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HW35_10645 cce0f6a9bb15b6ceba5298fc8d66ac1a 177 SMART SM00739 123 150 5.5E-6 T 12-10-2018 IPR005824 KOW HW35_05645 408590b6342d12b7719d72eb8e9d7cb7 419 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 2.9E-133 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_05645 408590b6342d12b7719d72eb8e9d7cb7 419 SUPERFAMILY SSF56672 16 356 3.94E-63 T 12-10-2018 HW35_05645 408590b6342d12b7719d72eb8e9d7cb7 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05645 408590b6342d12b7719d72eb8e9d7cb7 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05645 408590b6342d12b7719d72eb8e9d7cb7 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_05645 408590b6342d12b7719d72eb8e9d7cb7 419 Pfam PF08388 Group II intron, maturase-specific domain 288 360 6.7E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_05645 408590b6342d12b7719d72eb8e9d7cb7 419 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 8.7E-48 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_05090 ac29c5141e53ec9e375873375de262c9 340 SUPERFAMILY SSF53067 147 329 5.44E-50 T 12-10-2018 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 Gene3D G3DSA:3.30.420.40 9 324 1.4E-131 T 12-10-2018 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 129 148 6.1E-61 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 6.1E-61 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 6.1E-61 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 184 204 6.1E-61 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 297 323 6.1E-61 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 333 4.4E-159 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 Gene3D G3DSA:3.90.640.10 183 256 1.4E-131 T 12-10-2018 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 Gene3D G3DSA:3.30.420.40 151 314 1.4E-131 T 12-10-2018 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 Pfam PF06723 MreB/Mbl protein 7 331 4.4E-151 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_05090 ac29c5141e53ec9e375873375de262c9 340 SUPERFAMILY SSF53067 7 144 1.14E-38 T 12-10-2018 HW35_16225 c2bbac4d310288fea8a0d119c7c61eb1 176 Pfam PF02620 Uncharacterized ACR, COG1399 56 166 1.0E-20 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 Pfam PF00106 short chain dehydrogenase 9 200 2.0E-57 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 Gene3D G3DSA:3.40.50.720 3 260 1.4E-75 T 12-10-2018 HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 211 230 1.4E-56 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 172 195 1.4E-56 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 107 127 1.4E-56 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 237 256 1.4E-56 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 1.4E-56 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 87 104 1.4E-56 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 260 2.3E-111 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 5.0E-4 T 12-10-2018 HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 SUPERFAMILY SSF51735 8 259 4.71E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_12735 bfbb834e096ffc75fd9f04b1ed9b8c2d 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HW35_05080 08562a220e21a677895ed7f3d3e6c693 171 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 7 158 2.7E-22 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 HW35_05080 08562a220e21a677895ed7f3d3e6c693 171 Pfam PF04093 rod shape-determining protein MreD 2 157 7.8E-27 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 HW35_10885 1d423f5e4b32e8eeeb8316499d65fece 114 SUPERFAMILY SSF46785 2 98 4.99E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_10885 1d423f5e4b32e8eeeb8316499d65fece 114 Gene3D G3DSA:1.10.10.10 1 110 1.5E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_10885 1d423f5e4b32e8eeeb8316499d65fece 114 Pfam PF03551 Transcriptional regulator PadR-like family 10 81 5.1E-24 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal HW35_04240 c6020292250ada469d65c10a43475a03 324 SUPERFAMILY SSF53067 6 319 2.65E-76 T 12-10-2018 HW35_04240 c6020292250ada469d65c10a43475a03 324 Gene3D G3DSA:3.30.420.40 8 317 5.1E-112 T 12-10-2018 HW35_04240 c6020292250ada469d65c10a43475a03 324 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 7 323 2.9E-115 T 12-10-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 HW35_04240 c6020292250ada469d65c10a43475a03 324 ProSitePatterns PS01125 ROK family signature. 140 167 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 HW35_04240 c6020292250ada469d65c10a43475a03 324 Pfam PF00480 ROK family 7 320 1.7E-79 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 HW35_04240 c6020292250ada469d65c10a43475a03 324 Gene3D G3DSA:3.30.420.40 131 304 5.1E-112 T 12-10-2018 HW35_11860 b229342126d8d45eca930dca430af419 487 SUPERFAMILY SSF54675 6 140 8.98E-52 T 12-10-2018 HW35_11860 b229342126d8d45eca930dca430af419 487 Gene3D G3DSA:3.20.20.70 153 320 7.0E-208 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_11860 b229342126d8d45eca930dca430af419 487 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 158 339 5.4E-11 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 HW35_11860 b229342126d8d45eca930dca430af419 487 SUPERFAMILY SSF51690 141 479 5.0E-131 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 HW35_11860 b229342126d8d45eca930dca430af419 487 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 466 1.9E-184 T 12-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 HW35_11860 b229342126d8d45eca930dca430af419 487 Gene3D G3DSA:3.20.140.10 12 471 7.0E-208 T 12-10-2018 HW35_11860 b229342126d8d45eca930dca430af419 487 PIRSF PIRSF000484 5 481 2.6E-153 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 HW35_11695 b2f4d2bb1ffcfec52d3bffe4f7a71eaf 237 ProSitePatterns PS01058 SAICAR synthetase signature 2. 171 179 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11695 b2f4d2bb1ffcfec52d3bffe4f7a71eaf 237 SUPERFAMILY SSF56104 3 235 4.9E-83 T 12-10-2018 HW35_11695 b2f4d2bb1ffcfec52d3bffe4f7a71eaf 237 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 5 236 4.7E-82 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 HW35_11695 b2f4d2bb1ffcfec52d3bffe4f7a71eaf 237 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 2 233 34.166 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11695 b2f4d2bb1ffcfec52d3bffe4f7a71eaf 237 ProSitePatterns PS01057 SAICAR synthetase signature 1. 84 98 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_11695 b2f4d2bb1ffcfec52d3bffe4f7a71eaf 237 Gene3D G3DSA:3.30.200.20 5 230 5.5E-98 T 12-10-2018 HW35_11695 b2f4d2bb1ffcfec52d3bffe4f7a71eaf 237 Gene3D G3DSA:3.30.470.20 83 219 5.5E-98 T 12-10-2018 HW35_11695 b2f4d2bb1ffcfec52d3bffe4f7a71eaf 237 Pfam PF01259 SAICAR synthetase 5 228 7.2E-68 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HW35_01965 50d62b9f7582d4dcba3ab4d71b960426 307 SUPERFAMILY SSF81464 16 113 1.14E-17 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01965 50d62b9f7582d4dcba3ab4d71b960426 307 PIRSF PIRSF000292 2 306 5.8E-95 T 12-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 HW35_01965 50d62b9f7582d4dcba3ab4d71b960426 307 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 42 107 1.2E-5 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01965 50d62b9f7582d4dcba3ab4d71b960426 307 Gene3D G3DSA:2.60.40.420 111 265 2.4E-40 T 12-10-2018 IPR008972 Cupredoxin HW35_01965 50d62b9f7582d4dcba3ab4d71b960426 307 Gene3D G3DSA:1.10.287.90 25 110 3.1E-23 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01965 50d62b9f7582d4dcba3ab4d71b960426 307 SUPERFAMILY SSF49503 121 269 7.14E-42 T 12-10-2018 IPR008972 Cupredoxin HW35_01965 50d62b9f7582d4dcba3ab4d71b960426 307 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 10 236 4.4E-83 T 12-10-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 HW35_02380 848b0d128cfe4a797c94e1acf7fffd66 331 Gene3D G3DSA:3.40.50.2300 148 319 1.9E-86 T 12-10-2018 HW35_02380 848b0d128cfe4a797c94e1acf7fffd66 331 SUPERFAMILY SSF53822 39 235 8.52E-16 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_02380 848b0d128cfe4a797c94e1acf7fffd66 331 Gene3D G3DSA:3.40.50.2300 49 299 1.9E-86 T 12-10-2018 HW35_02380 848b0d128cfe4a797c94e1acf7fffd66 331 Pfam PF04392 ABC transporter substrate binding protein 38 324 7.2E-84 T 12-10-2018 IPR007487 ABC transporter, substrate-binding protein HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 SUPERFAMILY SSF52540 4 195 1.87E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 Pfam PF12848 ABC transporter 166 231 5.5E-9 T 12-10-2018 IPR032781 ABC-transporter extension domain HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 Pfam PF00005 ABC transporter 310 435 1.5E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 Pfam PF00005 ABC transporter 26 63 2.2E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 Gene3D G3DSA:3.40.50.300 76 231 3.2E-28 T 12-10-2018 HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 SUPERFAMILY SSF52540 301 482 1.2E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 Pfam PF00005 ABC transporter 92 126 3.6E-5 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 ProSitePatterns PS00211 ABC transporters family signature. 99 113 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 SMART SM00382 319 481 5.8E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 SMART SM00382 30 172 9.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 Gene3D G3DSA:3.40.50.300 1 75 1.2E-13 T 12-10-2018 HW35_12895 c2b302d22cb29014ca5681fe791c16d8 485 Gene3D G3DSA:3.40.50.300 289 485 8.0E-40 T 12-10-2018 HW35_14875 1fabce403d8c57928fa2cc533e608618 416 Pfam PF12698 ABC-2 family transporter protein 19 387 1.2E-56 T 12-10-2018 HW35_16550 28dd26bdd00b3e01e5a23474abb0a9f7 160 Gene3D G3DSA:3.90.45.10 1 156 2.3E-61 T 12-10-2018 IPR036821 Peptide deformylase superfamily HW35_16550 28dd26bdd00b3e01e5a23474abb0a9f7 160 PRINTS PR01576 Peptide deformylase signature 88 99 1.6E-36 T 12-10-2018 IPR023635 Peptide deformylase HW35_16550 28dd26bdd00b3e01e5a23474abb0a9f7 160 PRINTS PR01576 Peptide deformylase signature 33 62 1.6E-36 T 12-10-2018 IPR023635 Peptide deformylase HW35_16550 28dd26bdd00b3e01e5a23474abb0a9f7 160 PRINTS PR01576 Peptide deformylase signature 119 148 1.6E-36 T 12-10-2018 IPR023635 Peptide deformylase HW35_16550 28dd26bdd00b3e01e5a23474abb0a9f7 160 PRINTS PR01576 Peptide deformylase signature 100 118 1.6E-36 T 12-10-2018 IPR023635 Peptide deformylase HW35_16550 28dd26bdd00b3e01e5a23474abb0a9f7 160 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 156 2.6E-54 T 12-10-2018 IPR023635 Peptide deformylase HW35_16550 28dd26bdd00b3e01e5a23474abb0a9f7 160 PIRSF PIRSF004749 1 156 8.8E-51 T 12-10-2018 IPR023635 Peptide deformylase HW35_16550 28dd26bdd00b3e01e5a23474abb0a9f7 160 Hamap MF_00163 Peptide deformylase [def]. 2 158 29.563 T 12-10-2018 IPR023635 Peptide deformylase HW35_16550 28dd26bdd00b3e01e5a23474abb0a9f7 160 Pfam PF01327 Polypeptide deformylase 3 148 1.5E-49 T 12-10-2018 IPR023635 Peptide deformylase HW35_16550 28dd26bdd00b3e01e5a23474abb0a9f7 160 SUPERFAMILY SSF56420 2 150 6.67E-56 T 12-10-2018 IPR036821 Peptide deformylase superfamily HW35_04595 e94a20cf532f6b05b8380eb356c4795b 44 Pfam PF14141 YqzM-like protein 2 43 3.0E-26 T 12-10-2018 IPR025416 YqzM-like protein HW35_03685 c7b5eaa83d3301b9a202d38e8600fea2 389 SMART SM00936 279 370 6.8E-27 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_03685 c7b5eaa83d3301b9a202d38e8600fea2 389 Gene3D G3DSA:2.60.410.10 279 370 9.2E-23 T 12-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_03685 c7b5eaa83d3301b9a202d38e8600fea2 389 SUPERFAMILY SSF56601 4 279 1.7E-78 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_03685 c7b5eaa83d3301b9a202d38e8600fea2 389 SUPERFAMILY SSF69189 279 372 2.55E-22 T 12-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_03685 c7b5eaa83d3301b9a202d38e8600fea2 389 Gene3D G3DSA:3.40.710.10 18 278 5.7E-90 T 12-10-2018 HW35_03685 c7b5eaa83d3301b9a202d38e8600fea2 389 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 259 1.0E-88 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HW35_03685 c7b5eaa83d3301b9a202d38e8600fea2 389 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 279 370 9.9E-22 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_03685 c7b5eaa83d3301b9a202d38e8600fea2 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 62 73 4.4E-17 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_03685 c7b5eaa83d3301b9a202d38e8600fea2 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 115 132 4.4E-17 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_03685 c7b5eaa83d3301b9a202d38e8600fea2 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 142 155 4.4E-17 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_01020 cbe005de63d6373e8075574e2839a19d 137 SMART SM00881 15 107 5.8E-15 T 12-10-2018 IPR003781 CoA-binding GO:0048037 HW35_01020 cbe005de63d6373e8075574e2839a19d 137 Pfam PF13380 CoA binding domain 19 133 1.6E-36 T 12-10-2018 IPR003781 CoA-binding GO:0048037 HW35_01020 cbe005de63d6373e8075574e2839a19d 137 Gene3D G3DSA:3.40.50.720 1 137 1.6E-37 T 12-10-2018 HW35_01020 cbe005de63d6373e8075574e2839a19d 137 SUPERFAMILY SSF51735 9 135 1.34E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_09545 85ee17c96abe2a36f38846f9ed55c119 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 297 310 2.5E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HW35_09545 85ee17c96abe2a36f38846f9ed55c119 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 102 112 2.5E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HW35_09545 85ee17c96abe2a36f38846f9ed55c119 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 40 56 2.5E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HW35_09545 85ee17c96abe2a36f38846f9ed55c119 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 351 366 2.5E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HW35_09545 85ee17c96abe2a36f38846f9ed55c119 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 62 78 2.5E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HW35_09545 85ee17c96abe2a36f38846f9ed55c119 393 Gene3D G3DSA:3.40.50.2300 41 366 4.0E-108 T 12-10-2018 HW35_09545 85ee17c96abe2a36f38846f9ed55c119 393 Pfam PF13458 Periplasmic binding protein 39 383 1.5E-69 T 12-10-2018 IPR028081 Leucine-binding protein domain HW35_09545 85ee17c96abe2a36f38846f9ed55c119 393 SUPERFAMILY SSF53822 39 388 8.11E-96 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_09545 85ee17c96abe2a36f38846f9ed55c119 393 Gene3D G3DSA:3.40.50.2300 161 291 4.0E-108 T 12-10-2018 HW35_13410 330a1d0553190ea65eb47e2049cd582f 691 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 463 591 2.7E-35 T 12-10-2018 IPR025299 CstA, C-terminal domain HW35_13410 330a1d0553190ea65eb47e2049cd582f 691 Pfam PF02554 Carbon starvation protein CstA 32 408 2.3E-171 T 12-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 HW35_16930 745e63c8312fd21d0c55af798960ff9f 358 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 42 347 4.0E-85 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 HW35_16930 745e63c8312fd21d0c55af798960ff9f 358 Gene3D G3DSA:3.40.50.2300 148 343 3.8E-108 T 12-10-2018 HW35_16930 745e63c8312fd21d0c55af798960ff9f 358 Gene3D G3DSA:3.40.50.2300 44 308 3.8E-108 T 12-10-2018 HW35_16930 745e63c8312fd21d0c55af798960ff9f 358 SUPERFAMILY SSF53822 54 267 7.4E-12 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_02715 303123da7118b4c86a97eb926a403d42 479 TIGRFAM TIGR00238 TIGR00238: KamA family protein 14 342 2.6E-146 T 12-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HW35_02715 303123da7118b4c86a97eb926a403d42 479 Gene3D G3DSA:3.20.20.70 63 348 1.4E-117 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_02715 303123da7118b4c86a97eb926a403d42 479 Pfam PF13353 4Fe-4S single cluster domain 127 200 6.8E-5 T 12-10-2018 HW35_02715 303123da7118b4c86a97eb926a403d42 479 Gene3D G3DSA:2.40.50.600 349 414 1.3E-19 T 12-10-2018 HW35_02715 303123da7118b4c86a97eb926a403d42 479 SUPERFAMILY SSF102114 114 359 5.36E-33 T 12-10-2018 HW35_02715 303123da7118b4c86a97eb926a403d42 479 PIRSF PIRSF004911 1 402 2.8E-160 T 12-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HW35_02715 303123da7118b4c86a97eb926a403d42 479 Pfam PF12544 Lysine-2,3-aminomutase 321 447 2.9E-61 T 12-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain HW35_02715 303123da7118b4c86a97eb926a403d42 479 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 21 427 3.7E-193 T 12-10-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 HW35_16035 ac956a389a982e778021d5aca4bd9d02 66 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 1.0E-31 T 12-10-2018 IPR019241 Protein of unknown function DUF2197 HW35_07980 daab64a074808ace8a951cacc1bb3e59 352 Pfam PF00534 Glycosyl transferases group 1 174 331 2.6E-37 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 HW35_07980 daab64a074808ace8a951cacc1bb3e59 352 Gene3D G3DSA:3.40.50.2000 14 346 2.6E-74 T 12-10-2018 HW35_07980 daab64a074808ace8a951cacc1bb3e59 352 SUPERFAMILY SSF53756 7 351 4.32E-75 T 12-10-2018 HW35_07980 daab64a074808ace8a951cacc1bb3e59 352 Pfam PF13439 Glycosyltransferase Family 4 14 162 3.5E-18 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 HW35_07980 daab64a074808ace8a951cacc1bb3e59 352 Gene3D G3DSA:3.40.50.2000 161 337 2.6E-74 T 12-10-2018 HW35_02475 ed3eebd093e749e3277139bc4e156c2d 539 Gene3D G3DSA:3.40.50.300 1 279 2.1E-62 T 12-10-2018 HW35_02475 ed3eebd093e749e3277139bc4e156c2d 539 Pfam PF00005 ABC transporter 335 468 3.5E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_02475 ed3eebd093e749e3277139bc4e156c2d 539 SUPERFAMILY SSF52540 2 253 1.31E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02475 ed3eebd093e749e3277139bc4e156c2d 539 SMART SM00382 26 238 2.5E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_02475 ed3eebd093e749e3277139bc4e156c2d 539 SMART SM00382 344 516 6.1E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_02475 ed3eebd093e749e3277139bc4e156c2d 539 Gene3D G3DSA:3.40.50.300 283 539 9.1E-46 T 12-10-2018 HW35_02475 ed3eebd093e749e3277139bc4e156c2d 539 SUPERFAMILY SSF52540 295 529 7.92E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_02475 ed3eebd093e749e3277139bc4e156c2d 539 Pfam PF12848 ABC transporter 224 309 1.2E-20 T 12-10-2018 IPR032781 ABC-transporter extension domain HW35_02475 ed3eebd093e749e3277139bc4e156c2d 539 Pfam PF00005 ABC transporter 18 184 2.0E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12990 fc0f4f1ceca8e5a0b3dfb97f9f38c9b0 470 PIRSF PIRSF006060 3 467 5.2E-71 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HW35_12990 fc0f4f1ceca8e5a0b3dfb97f9f38c9b0 470 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 HW35_12990 fc0f4f1ceca8e5a0b3dfb97f9f38c9b0 470 Gene3D G3DSA:1.20.1740.10 16 469 1.0E-62 T 12-10-2018 HW35_12990 fc0f4f1ceca8e5a0b3dfb97f9f38c9b0 470 Pfam PF00324 Amino acid permease 27 434 9.3E-86 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 HW35_16340 b467f3ef14541a8dc36ba8156088b6ec 263 Pfam PF03799 Cell division protein FtsQ 122 238 1.2E-8 T 12-10-2018 IPR005548 Cell division protein FtsQ/DivIB HW35_16340 b467f3ef14541a8dc36ba8156088b6ec 263 Gene3D G3DSA:3.40.50.10960 117 233 2.1E-43 T 12-10-2018 HW35_16340 b467f3ef14541a8dc36ba8156088b6ec 263 Hamap MF_00912 Cell division protein DivIB [divIB]. 9 252 29.546 T 12-10-2018 IPR026580 Cell division protein DivIB HW35_16340 b467f3ef14541a8dc36ba8156088b6ec 263 Pfam PF08478 POTRA domain, FtsQ-type 51 118 6.1E-20 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type HW35_16340 b467f3ef14541a8dc36ba8156088b6ec 263 Gene3D G3DSA:3.10.20.310 50 116 1.8E-6 T 12-10-2018 HW35_04405 58c57ae8fdf89b299c05e083958d0041 121 PIRSF PIRSF000025 1 121 4.3E-40 T 12-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 HW35_04405 58c57ae8fdf89b299c05e083958d0041 121 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 50 117 3.1E-13 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_04405 58c57ae8fdf89b299c05e083958d0041 121 SUPERFAMILY SSF46626 9 120 1.36E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HW35_04405 58c57ae8fdf89b299c05e083958d0041 121 Gene3D G3DSA:1.10.760.10 52 121 6.5E-26 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HW35_15355 8a04f28be7f90bdb8e117b0fa4237783 605 Gene3D G3DSA:1.10.1370.20 234 605 8.2E-146 T 12-10-2018 HW35_15355 8a04f28be7f90bdb8e117b0fa4237783 605 SUPERFAMILY SSF55486 60 603 3.97E-141 T 12-10-2018 HW35_15355 8a04f28be7f90bdb8e117b0fa4237783 605 Gene3D G3DSA:1.20.140.70 30 185 2.3E-56 T 12-10-2018 HW35_15355 8a04f28be7f90bdb8e117b0fa4237783 605 Pfam PF01432 Peptidase family M3 211 590 4.7E-84 T 12-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 HW35_15355 8a04f28be7f90bdb8e117b0fa4237783 605 Gene3D G3DSA:1.10.287.830 187 233 2.7E-22 T 12-10-2018 HW35_15355 8a04f28be7f90bdb8e117b0fa4237783 605 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 13 603 6.6E-222 T 12-10-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 HW35_15355 8a04f28be7f90bdb8e117b0fa4237783 605 Pfam PF08439 Oligopeptidase F 120 189 2.6E-25 T 12-10-2018 IPR013647 Oligopeptidase F, N-terminal domain HW35_00280 18081d50fd1a30670add1778194989d6 523 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 15 108 2.3E-18 T 12-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 HW35_00280 18081d50fd1a30670add1778194989d6 523 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 239 512 2.5E-55 T 12-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 HW35_17375 96deaaa16b2240bd541d2df55643ecbd 90 Pfam PF10942 Protein of unknown function (DUF2619) 16 84 8.6E-29 T 12-10-2018 IPR020390 Uncharacterised protein family YqhV HW35_17375 96deaaa16b2240bd541d2df55643ecbd 90 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 6 89 3.0E-7 T 12-10-2018 IPR020390 Uncharacterised protein family YqhV HW35_01445 dd64f1056135830540b1fbf7f2319921 159 Gene3D G3DSA:3.40.1260.10 1 159 7.0E-68 T 12-10-2018 IPR027396 DsrEFH-like HW35_01445 dd64f1056135830540b1fbf7f2319921 159 SUPERFAMILY SSF75169 5 157 2.86E-23 T 12-10-2018 IPR027396 DsrEFH-like HW35_01445 dd64f1056135830540b1fbf7f2319921 159 Pfam PF13686 DsrE/DsrF/DrsH-like family 4 158 1.9E-67 T 12-10-2018 IPR032836 DsrE2-like family HW35_04080 1717fe7d48b26669cb9f513d6ee6f2c7 126 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 28 126 2.0E-11 T 12-10-2018 HW35_04435 0289dcd83cd810ded2a1110706234e30 213 SMART SM00116 154 205 0.0084 T 12-10-2018 IPR000644 CBS domain HW35_04435 0289dcd83cd810ded2a1110706234e30 213 SMART SM00116 87 135 0.0078 T 12-10-2018 IPR000644 CBS domain HW35_04435 0289dcd83cd810ded2a1110706234e30 213 SUPERFAMILY SSF54631 71 205 1.52E-23 T 12-10-2018 HW35_04435 0289dcd83cd810ded2a1110706234e30 213 Gene3D G3DSA:1.10.10.10 2 64 2.0E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_04435 0289dcd83cd810ded2a1110706234e30 213 Pfam PF00571 CBS domain 148 204 6.1E-6 T 12-10-2018 IPR000644 CBS domain HW35_04435 0289dcd83cd810ded2a1110706234e30 213 Pfam PF00571 CBS domain 82 134 3.0E-6 T 12-10-2018 IPR000644 CBS domain HW35_04435 0289dcd83cd810ded2a1110706234e30 213 SUPERFAMILY SSF46785 6 78 2.32E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_04435 0289dcd83cd810ded2a1110706234e30 213 Pfam PF08279 HTH domain 10 62 2.1E-13 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 HW35_04435 0289dcd83cd810ded2a1110706234e30 213 PIRSF PIRSF026546 5 211 2.5E-103 T 12-10-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS HW35_04435 0289dcd83cd810ded2a1110706234e30 213 Gene3D G3DSA:3.10.580.10 65 212 7.4E-60 T 12-10-2018 HW35_01425 eee6e227f235e94054fb18f8e15f7785 76 SUPERFAMILY SSF64307 2 75 7.59E-24 T 12-10-2018 IPR036868 TusA-like domain superfamily HW35_01425 eee6e227f235e94054fb18f8e15f7785 76 Gene3D G3DSA:3.30.110.40 1 75 1.5E-27 T 12-10-2018 IPR036868 TusA-like domain superfamily HW35_01425 eee6e227f235e94054fb18f8e15f7785 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 12-10-2018 IPR001455 TusA-like domain HW35_01425 eee6e227f235e94054fb18f8e15f7785 76 Pfam PF01206 Sulfurtransferase TusA 6 74 5.2E-22 T 12-10-2018 IPR001455 TusA-like domain HW35_00260 fe05b1f9cd98f2cb4dde5f2d4c73468f 137 Gene3D G3DSA:1.20.120.490 16 137 9.9E-38 T 12-10-2018 IPR024042 TM1646-like domain superfamily HW35_00260 fe05b1f9cd98f2cb4dde5f2d4c73468f 137 Pfam PF03885 Protein of unknown function (DUF327) 13 136 2.1E-38 T 12-10-2018 IPR005585 Protein of unknown function DUF327 HW35_00260 fe05b1f9cd98f2cb4dde5f2d4c73468f 137 SUPERFAMILY SSF158397 18 137 2.35E-33 T 12-10-2018 IPR024042 TM1646-like domain superfamily HW35_15880 0fa3957b36bee5ff7169950efe31d979 148 Gene3D G3DSA:3.10.580.10 1 148 3.1E-50 T 12-10-2018 HW35_15880 0fa3957b36bee5ff7169950efe31d979 148 SUPERFAMILY SSF54631 12 139 2.27E-26 T 12-10-2018 HW35_09170 28002f85dcd7b34530cbd4ac1035c9ee 348 Pfam PF03481 Putative GTP-binding controlling metal-binding 205 341 3.9E-27 T 12-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain HW35_09170 28002f85dcd7b34530cbd4ac1035c9ee 348 SUPERFAMILY SSF55821 21 210 3.97E-66 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily HW35_09170 28002f85dcd7b34530cbd4ac1035c9ee 348 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 17 214 6.0E-66 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 HW35_09170 28002f85dcd7b34530cbd4ac1035c9ee 348 Gene3D G3DSA:3.90.870.10 3 219 3.7E-83 T 12-10-2018 HW35_09170 28002f85dcd7b34530cbd4ac1035c9ee 348 Pfam PF01300 Telomere recombination 27 203 4.4E-60 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 HW35_09170 28002f85dcd7b34530cbd4ac1035c9ee 348 Gene3D G3DSA:3.40.50.11030 222 348 1.8E-40 T 12-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily HW35_09170 28002f85dcd7b34530cbd4ac1035c9ee 348 PIRSF PIRSF004930 1 347 4.8E-132 T 12-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 Pfam PF13414 TPR repeat 41 81 3.9E-10 T 12-10-2018 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 Pfam PF07719 Tetratricopeptide repeat 4 33 1.5E-6 T 12-10-2018 IPR013105 Tetratricopeptide repeat 2 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 Gene3D G3DSA:1.25.40.10 2 99 1.9E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 Gene3D G3DSA:1.25.40.10 100 217 2.1E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 SUPERFAMILY SSF48452 8 204 1.31E-39 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 Pfam PF00515 Tetratricopeptide repeat 171 203 1.7E-9 T 12-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 SMART SM00028 102 135 13.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 SMART SM00028 34 67 1.6E-6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 SMART SM00028 136 169 0.005 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 SMART SM00028 170 203 1.5E-7 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 SMART SM00028 68 101 0.68 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 SMART SM00028 4 33 32.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 Pfam PF13181 Tetratricopeptide repeat 136 169 2.1E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_04805 28b6e8d26c99d8b82adb898300a59221 217 Pfam PF13181 Tetratricopeptide repeat 104 135 0.11 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_00660 4f8e49177b8468e97a9cc6d9ba5fee32 83 SUPERFAMILY SSF52833 4 68 2.76E-15 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_00660 4f8e49177b8468e97a9cc6d9ba5fee32 83 Gene3D G3DSA:3.40.30.10 4 81 1.7E-16 T 12-10-2018 HW35_00660 4f8e49177b8468e97a9cc6d9ba5fee32 83 Pfam PF00462 Glutaredoxin 5 61 1.9E-10 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 SMART SM00493 262 333 6.2E-12 T 12-10-2018 IPR006171 TOPRIM domain HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 Pfam PF13155 Toprim-like 265 350 1.3E-16 T 12-10-2018 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 Hamap MF_00974 DNA primase [dnaG]. 4 581 28.976 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 Pfam PF10410 DnaB-helicase binding domain of primase 372 424 1.2E-8 T 12-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 255 4.5E-44 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 SMART SM00400 36 90 7.5E-36 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 SUPERFAMILY SSF56731 119 425 2.49E-98 T 12-10-2018 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 TIGRFAM TIGR01391 dnaG: DNA primase 4 420 8.4E-149 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 Gene3D G3DSA:3.40.1360.10 244 368 2.7E-36 T 12-10-2018 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 Gene3D G3DSA:3.90.580.10 1 102 7.4E-44 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 SUPERFAMILY SSF48024 463 563 2.35E-9 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 PIRSF PIRSF002811 2 601 3.5E-185 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 Pfam PF01807 CHC2 zinc finger 6 100 3.3E-40 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 SUPERFAMILY SSF57783 4 98 2.38E-38 T 12-10-2018 HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 Gene3D G3DSA:1.10.860.10 466 563 1.6E-31 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal HW35_04420 13ee42a6d9542ebf6725858cf40e94dc 601 Gene3D G3DSA:3.90.980.10 113 243 5.6E-49 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily HW35_05855 95a4904db23c0b84d3dd965422283dc4 381 Gene3D G3DSA:3.40.640.10 13 255 1.0E-139 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_05855 95a4904db23c0b84d3dd965422283dc4 381 Pfam PF00266 Aminotransferase class-V 2 361 9.7E-81 T 12-10-2018 IPR000192 Aminotransferase class V domain HW35_05855 95a4904db23c0b84d3dd965422283dc4 381 SUPERFAMILY SSF53383 1 374 2.66E-106 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_05855 95a4904db23c0b84d3dd965422283dc4 381 Gene3D G3DSA:3.90.1150.10 2 371 1.0E-139 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_05855 95a4904db23c0b84d3dd965422283dc4 381 PIRSF PIRSF005572 1 379 3.4E-124 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 HW35_06995 f0953e14e0dbfab17dae54a331bb8ab0 91 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 1.6E-39 T 12-10-2018 IPR009370 Protein of unknown function DUF1027 HW35_06995 f0953e14e0dbfab17dae54a331bb8ab0 91 Gene3D G3DSA:3.50.4.20 1 91 4.3E-44 T 12-10-2018 IPR038141 YutD-like superfamily HW35_06995 f0953e14e0dbfab17dae54a331bb8ab0 91 PIRSF PIRSF012565 1 91 4.9E-49 T 12-10-2018 IPR009370 Protein of unknown function DUF1027 HW35_15015 add53badd80f9de8b87eb498236833a5 243 Pfam PF03591 AzlC protein 23 158 3.0E-40 T 12-10-2018 IPR011606 Branched-chain amino acid transport, permease HW35_01925 6819ce99d94fc8eaa77f394532ce6ae9 246 Pfam PF00557 Metallopeptidase family M24 12 238 5.1E-47 T 12-10-2018 IPR000994 Peptidase M24 HW35_01925 6819ce99d94fc8eaa77f394532ce6ae9 246 SUPERFAMILY SSF55920 3 246 5.63E-71 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like HW35_01925 6819ce99d94fc8eaa77f394532ce6ae9 246 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 246 1.1E-87 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_01925 6819ce99d94fc8eaa77f394532ce6ae9 246 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 3.4E-19 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_01925 6819ce99d94fc8eaa77f394532ce6ae9 246 PRINTS PR00599 Methionine aminopeptidase-1 signature 66 79 3.4E-19 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_01925 6819ce99d94fc8eaa77f394532ce6ae9 246 PRINTS PR00599 Methionine aminopeptidase-1 signature 158 170 3.4E-19 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_01925 6819ce99d94fc8eaa77f394532ce6ae9 246 PRINTS PR00599 Methionine aminopeptidase-1 signature 88 104 3.4E-19 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_01925 6819ce99d94fc8eaa77f394532ce6ae9 246 Hamap MF_01974 Methionine aminopeptidase [map]. 1 246 33.745 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_01925 6819ce99d94fc8eaa77f394532ce6ae9 246 Gene3D G3DSA:3.90.230.10 1 246 1.3E-86 T 12-10-2018 HW35_17015 837f193568a401407501ff0500318413 577 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 175 2.1E-41 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HW35_17015 837f193568a401407501ff0500318413 577 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 474 550 3.9E-11 T 12-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HW35_17015 837f193568a401407501ff0500318413 577 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 572 1.7E-216 T 12-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 HW35_17015 837f193568a401407501ff0500318413 577 SUPERFAMILY SSF52922 468 576 1.44E-24 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HW35_17015 837f193568a401407501ff0500318413 577 SUPERFAMILY SSF52518 195 456 2.73E-74 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_17015 837f193568a401407501ff0500318413 577 Gene3D G3DSA:3.40.920.10 1 184 3.8E-28 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HW35_17015 837f193568a401407501ff0500318413 577 Gene3D G3DSA:3.40.50.970 185 385 7.3E-77 T 12-10-2018 HW35_17015 837f193568a401407501ff0500318413 577 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 209 450 1.4E-62 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HW35_17015 837f193568a401407501ff0500318413 577 SUPERFAMILY SSF53323 1 220 3.4E-44 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HW35_17015 837f193568a401407501ff0500318413 577 Gene3D G3DSA:3.40.50.920 465 577 1.0E-29 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HW35_03035 69bd763578d737f4d46b9242865e8173 297 Pfam PF00892 EamA-like transporter family 152 287 2.9E-25 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_03035 69bd763578d737f4d46b9242865e8173 297 Pfam PF00892 EamA-like transporter family 6 140 2.3E-21 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_03035 69bd763578d737f4d46b9242865e8173 297 SUPERFAMILY SSF103481 187 291 6.02E-14 T 12-10-2018 HW35_03035 69bd763578d737f4d46b9242865e8173 297 SUPERFAMILY SSF103481 40 140 1.29E-14 T 12-10-2018 HW35_15230 db8e732b46f8d3a449aaef7a25c1858d 60 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 2.9E-21 T 12-10-2018 IPR021324 Protein of unknown function DUF2929 HW35_06110 000666ff79b8b57b738cebe217a23f70 101 Gene3D G3DSA:3.40.250.10 4 100 7.8E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_06110 000666ff79b8b57b738cebe217a23f70 101 Pfam PF00581 Rhodanese-like domain 8 97 2.1E-13 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_06110 000666ff79b8b57b738cebe217a23f70 101 SUPERFAMILY SSF52821 3 98 7.73E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_06110 000666ff79b8b57b738cebe217a23f70 101 SMART SM00450 8 99 3.4E-13 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_11845 35ed29c9cb8656a92cbcc147f3fe2f23 208 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 191 2.2E-53 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HW35_11845 35ed29c9cb8656a92cbcc147f3fe2f23 208 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 4 190 18.636 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HW35_11845 35ed29c9cb8656a92cbcc147f3fe2f23 208 SMART SM01207 7 182 1.5E-70 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HW35_11845 35ed29c9cb8656a92cbcc147f3fe2f23 208 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 180 1.3E-48 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HW35_01935 97490b865fa0a5c9d63806a77d16669a 260 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 231 4.0E-22 T 12-10-2018 HW35_01935 97490b865fa0a5c9d63806a77d16669a 260 Gene3D G3DSA:3.40.50.1000 3 253 1.5E-47 T 12-10-2018 IPR023214 HAD superfamily HW35_01935 97490b865fa0a5c9d63806a77d16669a 260 SUPERFAMILY SSF56784 1 259 1.06E-40 T 12-10-2018 IPR036412 HAD-like superfamily HW35_01935 97490b865fa0a5c9d63806a77d16669a 260 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 165 231 2.2E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HW35_01935 97490b865fa0a5c9d63806a77d16669a 260 Gene3D G3DSA:1.20.120.710 15 130 1.5E-47 T 12-10-2018 HW35_01935 97490b865fa0a5c9d63806a77d16669a 260 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 139 225 1.7E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HW35_13970 2f0043238b617124c50282c8086407da 348 Gene3D G3DSA:3.30.200.20 1 99 4.0E-24 T 12-10-2018 HW35_13970 2f0043238b617124c50282c8086407da 348 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 26 337 2.0E-85 T 12-10-2018 IPR014255 Spore coat protein CotS HW35_13970 2f0043238b617124c50282c8086407da 348 Gene3D G3DSA:3.90.1200.10 100 338 1.5E-66 T 12-10-2018 HW35_13970 2f0043238b617124c50282c8086407da 348 SUPERFAMILY SSF56112 7 309 2.92E-39 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_13970 2f0043238b617124c50282c8086407da 348 Pfam PF01636 Phosphotransferase enzyme family 34 254 3.2E-14 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase HW35_10295 9011b3852fb3aa72d4fdc00d4c08a72c 541 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 366 513 9.1E-19 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HW35_10295 9011b3852fb3aa72d4fdc00d4c08a72c 541 Pfam PF01943 Polysaccharide biosynthesis protein 11 314 2.6E-37 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HW35_10295 9011b3852fb3aa72d4fdc00d4c08a72c 541 PIRSF PIRSF038958 5 532 1.4E-75 T 12-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type HW35_12085 cdd51dc2b585a2f28ff258b88b181e7a 332 SUPERFAMILY SSF53822 47 321 2.54E-65 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_12085 cdd51dc2b585a2f28ff258b88b181e7a 332 Gene3D G3DSA:3.40.50.2300 59 313 2.1E-76 T 12-10-2018 HW35_12085 cdd51dc2b585a2f28ff258b88b181e7a 332 Gene3D G3DSA:3.40.50.2300 150 319 2.1E-76 T 12-10-2018 HW35_12085 cdd51dc2b585a2f28ff258b88b181e7a 332 Pfam PF13407 Periplasmic binding protein domain 49 304 1.3E-56 T 12-10-2018 IPR025997 Periplasmic binding protein HW35_16015 02aef3b8b0cf37c6b0f41fa7359f9014 61 ProDom PD699877 YLAF TRANSMEMBRANE MEMBRANE BH2633 1 56 5.0E-6 T 12-10-2018 IPR035211 Protein of unknown function DUF5325 HW35_16015 02aef3b8b0cf37c6b0f41fa7359f9014 61 Pfam PF17259 Family of unknown function (DUF5325) 1 61 4.0E-29 T 12-10-2018 IPR035211 Protein of unknown function DUF5325 HW35_02320 8842446ede5914af46ccc8d321915af8 539 SUPERFAMILY SSF49842 381 516 1.24E-5 T 12-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 HW35_02320 8842446ede5914af46ccc8d321915af8 539 Pfam PF01391 Collagen triple helix repeat (20 copies) 100 158 4.1E-8 T 12-10-2018 IPR008160 Collagen triple helix repeat HW35_02320 8842446ede5914af46ccc8d321915af8 539 Pfam PF01391 Collagen triple helix repeat (20 copies) 316 374 6.1E-8 T 12-10-2018 IPR008160 Collagen triple helix repeat HW35_16825 675e4345652bec2a673ddcc28534ef38 100 SUPERFAMILY SSF55315 4 99 7.85E-26 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like HW35_16825 675e4345652bec2a673ddcc28534ef38 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 6 95 2.6E-18 T 12-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 HW35_16825 675e4345652bec2a673ddcc28534ef38 100 Gene3D G3DSA:3.30.1330.30 2 100 1.1E-36 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like HW35_02255 e33777786660ab0afa275766744e2ec9 176 SUPERFAMILY SSF101874 5 175 5.75E-58 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily HW35_02255 e33777786660ab0afa275766744e2ec9 176 Pfam PF04264 YceI-like domain 6 173 3.6E-47 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like HW35_02255 e33777786660ab0afa275766744e2ec9 176 SMART SM00867 5 174 8.1E-73 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like HW35_02255 e33777786660ab0afa275766744e2ec9 176 Gene3D G3DSA:2.40.128.110 4 176 2.8E-56 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily HW35_12985 193685e39b583ed0e0d02899abd7188a 289 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 26 289 38.844 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 HW35_12985 193685e39b583ed0e0d02899abd7188a 289 Gene3D G3DSA:1.20.58.480 30 289 2.7E-94 T 12-10-2018 HW35_12985 193685e39b583ed0e0d02899abd7188a 289 SUPERFAMILY SSF140959 32 289 1.7E-99 T 12-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 HW35_12985 193685e39b583ed0e0d02899abd7188a 289 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 26 288 2.2E-122 T 12-10-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 HW35_12985 193685e39b583ed0e0d02899abd7188a 289 Pfam PF03301 Tryptophan 2,3-dioxygenase 172 289 1.0E-23 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 HW35_12985 193685e39b583ed0e0d02899abd7188a 289 Pfam PF03301 Tryptophan 2,3-dioxygenase 25 161 3.6E-44 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 HW35_12030 6086a741f5cae7710becb36b4cf155a4 178 Pfam PF04308 Ribonuclease H-like 23 178 1.1E-49 T 12-10-2018 IPR007405 Bacteriophage KVP40, Orf299 HW35_01055 d3e22a93ea9b9d4742b557554c2a65cb 83 Pfam PF10752 Protein of unknown function (DUF2533) 1 81 2.6E-31 T 12-10-2018 IPR019688 Protein of unknown function DUF2533 HW35_04940 193a2977e1b173dc59d8e7e0ed4d4906 141 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 21 133 2.2E-31 T 12-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane HW35_04940 193a2977e1b173dc59d8e7e0ed4d4906 141 Pfam PF12670 Protein of unknown function (DUF3792) 20 130 6.0E-26 T 12-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane HW35_17695 dd172e2a4b65b3feacb17e7a6fa333bf 398 Gene3D G3DSA:3.90.1150.10 256 390 7.0E-48 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_17695 dd172e2a4b65b3feacb17e7a6fa333bf 398 SUPERFAMILY SSF53383 16 389 1.34E-110 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_17695 dd172e2a4b65b3feacb17e7a6fa333bf 398 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 389 9.9E-133 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_17695 dd172e2a4b65b3feacb17e7a6fa333bf 398 Gene3D G3DSA:3.40.640.10 5 255 7.6E-81 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_17695 dd172e2a4b65b3feacb17e7a6fa333bf 398 PIRSF PIRSF001434 1 392 2.6E-139 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HW35_04850 4d6d98209d51f433245caf824f5f04b3 493 ProSitePatterns PS00211 ABC transporters family signature. 394 408 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_04850 4d6d98209d51f433245caf824f5f04b3 493 Pfam PF00005 ABC transporter 18 168 1.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_04850 4d6d98209d51f433245caf824f5f04b3 493 Gene3D G3DSA:3.40.50.300 1 235 7.7E-60 T 12-10-2018 HW35_04850 4d6d98209d51f433245caf824f5f04b3 493 SUPERFAMILY SSF52540 3 220 8.04E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04850 4d6d98209d51f433245caf824f5f04b3 493 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_04850 4d6d98209d51f433245caf824f5f04b3 493 Gene3D G3DSA:3.40.50.300 239 490 2.6E-45 T 12-10-2018 HW35_04850 4d6d98209d51f433245caf824f5f04b3 493 Pfam PF00005 ABC transporter 268 421 1.0E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_04850 4d6d98209d51f433245caf824f5f04b3 493 SMART SM00382 27 224 1.0E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_04850 4d6d98209d51f433245caf824f5f04b3 493 SMART SM00382 276 470 1.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_04850 4d6d98209d51f433245caf824f5f04b3 493 SUPERFAMILY SSF52540 239 481 4.84E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_13405 d7531ac8a9e25fbe83880fb2f6e9fede 67 Pfam PF04328 Selenoprotein, putative 5 67 1.6E-23 T 12-10-2018 IPR007423 Selenoprotein, putative HW35_08435 73d933e9d7e1e55d9808a396cff6556b 211 Gene3D G3DSA:3.40.109.10 2 211 1.1E-62 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HW35_08435 73d933e9d7e1e55d9808a396cff6556b 211 Pfam PF00881 Nitroreductase family 15 191 3.1E-32 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 HW35_08435 73d933e9d7e1e55d9808a396cff6556b 211 SUPERFAMILY SSF55469 9 210 5.1E-55 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HW35_00595 fb957bed7abef704470f6c9a4ceeba4d 68 Pfam PF00403 Heavy-metal-associated domain 5 66 4.2E-19 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HW35_00595 fb957bed7abef704470f6c9a4ceeba4d 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 4 68 5.0E-29 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 HW35_00595 fb957bed7abef704470f6c9a4ceeba4d 68 SUPERFAMILY SSF55008 1 68 5.11E-22 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 HW35_00595 fb957bed7abef704470f6c9a4ceeba4d 68 PRINTS PR00944 Copper ion binding protein signature 15 28 2.6E-11 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 HW35_00595 fb957bed7abef704470f6c9a4ceeba4d 68 PRINTS PR00944 Copper ion binding protein signature 28 41 2.6E-11 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 HW35_00595 fb957bed7abef704470f6c9a4ceeba4d 68 PRINTS PR00944 Copper ion binding protein signature 54 67 2.6E-11 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 HW35_00595 fb957bed7abef704470f6c9a4ceeba4d 68 PRINTS PR00944 Copper ion binding protein signature 3 15 2.6E-11 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 HW35_00595 fb957bed7abef704470f6c9a4ceeba4d 68 Gene3D G3DSA:3.30.70.100 1 68 3.2E-27 T 12-10-2018 HW35_00595 fb957bed7abef704470f6c9a4ceeba4d 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HW35_09230 200f210e09c2425eb1182cde515043a9 285 PIRSF PIRSF001359 1 285 1.6E-129 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HW35_09230 200f210e09c2425eb1182cde515043a9 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HW35_09230 200f210e09c2425eb1182cde515043a9 285 Gene3D G3DSA:3.20.20.70 1 285 4.7E-119 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_09230 200f210e09c2425eb1182cde515043a9 285 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HW35_09230 200f210e09c2425eb1182cde515043a9 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 2.6E-107 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HW35_09230 200f210e09c2425eb1182cde515043a9 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 2.8E-116 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HW35_09230 200f210e09c2425eb1182cde515043a9 285 SUPERFAMILY SSF51569 1 285 2.93E-108 T 12-10-2018 HW35_09230 200f210e09c2425eb1182cde515043a9 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 6.3E-134 T 12-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 HW35_07195 e9bd4304eb6caeec6eca1b48f5cf078d 328 SUPERFAMILY SSF53807 44 322 1.83E-70 T 12-10-2018 HW35_07195 e9bd4304eb6caeec6eca1b48f5cf078d 328 Pfam PF01497 Periplasmic binding protein 61 301 5.2E-34 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain HW35_07195 e9bd4304eb6caeec6eca1b48f5cf078d 328 Gene3D G3DSA:3.40.50.1980 38 146 1.2E-34 T 12-10-2018 HW35_07195 e9bd4304eb6caeec6eca1b48f5cf078d 328 Gene3D G3DSA:3.40.50.1980 148 328 5.9E-62 T 12-10-2018 HW35_13460 154cdae0b5ff9f90a30d88511b5ab3f6 394 TIGRFAM TIGR00277 HDIG: HDIG domain 209 300 2.9E-8 T 12-10-2018 IPR006675 HDIG domain HW35_13460 154cdae0b5ff9f90a30d88511b5ab3f6 394 Gene3D G3DSA:1.10.3210.10 186 382 1.1E-72 T 12-10-2018 HW35_13460 154cdae0b5ff9f90a30d88511b5ab3f6 394 SMART SM00471 205 341 7.1E-14 T 12-10-2018 IPR003607 HD/PDEase domain HW35_13460 154cdae0b5ff9f90a30d88511b5ab3f6 394 SUPERFAMILY SSF109604 198 371 4.82E-42 T 12-10-2018 HW35_13460 154cdae0b5ff9f90a30d88511b5ab3f6 394 Pfam PF01966 HD domain 211 332 1.5E-23 T 12-10-2018 IPR006674 HD domain HW35_04085 fc7aaf193e13815e486adfca9ff3cb3d 294 Pfam PF01734 Patatin-like phospholipase 6 195 1.6E-30 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 HW35_04085 fc7aaf193e13815e486adfca9ff3cb3d 294 Gene3D G3DSA:3.40.1090.10 111 249 2.1E-20 T 12-10-2018 HW35_04085 fc7aaf193e13815e486adfca9ff3cb3d 294 SUPERFAMILY SSF52151 6 286 2.28E-43 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase HW35_04085 fc7aaf193e13815e486adfca9ff3cb3d 294 Gene3D G3DSA:3.40.1090.20 2 102 3.4E-21 T 12-10-2018 HW35_09640 c213c0274819d64ce22101ff326138bd 448 PIRSF PIRSF002746 1 448 1.6E-177 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 HW35_09640 c213c0274819d64ce22101ff326138bd 448 Pfam PF02447 GntP family permease 1 446 4.4E-181 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 HW35_09640 c213c0274819d64ce22101ff326138bd 448 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 448 8.3E-202 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 HW35_02215 6f95d516bea91e1f85a709677d859332 277 Pfam PF00665 Integrase core domain 117 228 1.4E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_02215 6f95d516bea91e1f85a709677d859332 277 Gene3D G3DSA:3.30.420.10 115 258 2.4E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_02215 6f95d516bea91e1f85a709677d859332 277 Pfam PF13276 HTH-like domain 34 87 1.8E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_02215 6f95d516bea91e1f85a709677d859332 277 SUPERFAMILY SSF53098 119 270 1.32E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 4.8E-48 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 SUPERFAMILY SSF52283 1 360 9.35E-67 T 12-10-2018 HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 SMART SM01003 4 136 2.5E-77 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 Gene3D G3DSA:3.40.50.720 129 305 9.0E-143 T 12-10-2018 HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 1.5E-188 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 12-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 SUPERFAMILY SSF51735 136 303 7.24E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 2.0E-84 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 Gene3D G3DSA:3.40.50.720 3 353 9.0E-143 T 12-10-2018 HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 SMART SM01002 148 297 6.7E-92 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HW35_14720 5ae0acbf276309dffdd57894fbb9f224 377 PIRSF PIRSF000183 1 371 1.8E-192 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 HW35_02185 f5a693752cf68be971e58ba39da0e6b1 322 Pfam PF13536 Putative multidrug resistance efflux transporter 38 305 6.0E-109 T 12-10-2018 IPR032713 Putative multidrug resistance efflux transporter HW35_06640 d54608d1a48028019a92589518e89485 134 Pfam PF02600 Disulfide bond formation protein DsbB 5 124 9.6E-12 T 12-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 HW35_06640 d54608d1a48028019a92589518e89485 134 Gene3D G3DSA:1.20.1550.10 2 112 7.4E-14 T 12-10-2018 IPR023380 DsbB-like superfamily HW35_06640 d54608d1a48028019a92589518e89485 134 PIRSF PIRSF036659 1 134 2.8E-54 T 12-10-2018 IPR012187 Disulphide bond formation protein BdbC HW35_06640 d54608d1a48028019a92589518e89485 134 SUPERFAMILY SSF158442 5 129 6.15E-31 T 12-10-2018 IPR023380 DsbB-like superfamily HW35_06640 d54608d1a48028019a92589518e89485 134 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 2 133 22.454 T 12-10-2018 IPR012187 Disulphide bond formation protein BdbC HW35_13920 d45280589c52c9c2f61cd1bb0cf83390 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 114 2.0E-22 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 HW35_13920 d45280589c52c9c2f61cd1bb0cf83390 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 119 17.808 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 HW35_13920 d45280589c52c9c2f61cd1bb0cf83390 124 TIGRFAM TIGR00494 crcB: protein CrcB 5 116 1.5E-23 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 HW35_05155 64ba437661598667e9ce84b40429ec73 376 Gene3D G3DSA:3.30.1490.300 82 169 4.0E-24 T 12-10-2018 HW35_05155 64ba437661598667e9ce84b40429ec73 376 Gene3D G3DSA:3.30.420.40 9 372 4.0E-24 T 12-10-2018 HW35_05155 64ba437661598667e9ce84b40429ec73 376 Gene3D G3DSA:3.30.420.40 208 343 4.0E-24 T 12-10-2018 HW35_06315 b238b00254cc0dd90e672d399c2ed122 431 Pfam PF00860 Permease family 16 393 1.5E-45 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 HW35_06315 b238b00254cc0dd90e672d399c2ed122 431 PIRSF PIRSF005353 1 431 6.6E-165 T 12-10-2018 IPR026033 Purine permease PbuG-like HW35_04205 8b7d35331b02d1be1e0fd2fa050cc031 355 SMART SM00382 137 256 0.004 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_04205 8b7d35331b02d1be1e0fd2fa050cc031 355 Gene3D G3DSA:3.30.450.90 2 111 6.2E-27 T 12-10-2018 HW35_04205 8b7d35331b02d1be1e0fd2fa050cc031 355 Gene3D G3DSA:3.40.50.300 112 350 1.2E-66 T 12-10-2018 HW35_04205 8b7d35331b02d1be1e0fd2fa050cc031 355 SUPERFAMILY SSF52540 6 306 2.04E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04205 8b7d35331b02d1be1e0fd2fa050cc031 355 Pfam PF00437 Type II/IV secretion system protein 13 275 1.3E-69 T 12-10-2018 IPR001482 Type II/IV secretion system protein HW35_04205 8b7d35331b02d1be1e0fd2fa050cc031 355 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 205 219 - T 12-10-2018 IPR001482 Type II/IV secretion system protein HW35_03875 bcf249824f1a7386d1e43860e9719101 621 Gene3D G3DSA:3.40.50.280 477 614 2.6E-22 T 12-10-2018 HW35_03875 bcf249824f1a7386d1e43860e9719101 621 Pfam PF01642 Methylmalonyl-CoA mutase 37 114 6.7E-14 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_03875 bcf249824f1a7386d1e43860e9719101 621 Pfam PF01642 Methylmalonyl-CoA mutase 143 514 3.2E-102 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_03875 bcf249824f1a7386d1e43860e9719101 621 Gene3D G3DSA:3.20.20.240 35 470 3.4E-140 T 12-10-2018 HW35_03875 bcf249824f1a7386d1e43860e9719101 621 SUPERFAMILY SSF51703 4 513 1.88E-115 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 HW35_10155 1c24f2c7cf23a70c90ad5b5fe19e3a45 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 3.6E-54 T 12-10-2018 IPR010375 Cyclic-di-AMP receptor HW35_10155 1c24f2c7cf23a70c90ad5b5fe19e3a45 109 SUPERFAMILY SSF54913 1 107 1.36E-12 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta HW35_10155 1c24f2c7cf23a70c90ad5b5fe19e3a45 109 Gene3D G3DSA:3.30.70.120 1 103 1.7E-44 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HW35_15095 12b579a64218f7beb1c787cc3fb4d174 81 Pfam PF10803 Spore germination GerPB 1 52 4.3E-29 T 12-10-2018 IPR024255 Spore germination GerPB HW35_15095 12b579a64218f7beb1c787cc3fb4d174 81 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 51 3.0E-13 T 12-10-2018 IPR024255 Spore germination GerPB HW35_04835 5212f2054b408ceb21ef3f4319205c18 97 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 95 5.7E-8 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 HW35_04835 5212f2054b408ceb21ef3f4319205c18 97 Gene3D G3DSA:2.60.300.12 1 97 4.5E-8 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 HW35_04835 5212f2054b408ceb21ef3f4319205c18 97 SUPERFAMILY SSF89360 2 97 1.7E-13 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 HW35_04835 5212f2054b408ceb21ef3f4319205c18 97 PIRSF PIRSF034852 1 97 2.2E-37 T 12-10-2018 IPR008326 Uncharacterised conserved protein UCP034852 HW35_04905 6fc3ffd0f55c6d49bf9038e2efd6a601 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.701 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 HW35_04905 6fc3ffd0f55c6d49bf9038e2efd6a601 170 SUPERFAMILY SSF53271 3 163 2.7E-49 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_04905 6fc3ffd0f55c6d49bf9038e2efd6a601 170 Pfam PF00156 Phosphoribosyl transferase domain 33 149 4.5E-16 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HW35_04905 6fc3ffd0f55c6d49bf9038e2efd6a601 170 Gene3D G3DSA:3.40.50.2020 1 170 1.1E-60 T 12-10-2018 HW35_04905 6fc3ffd0f55c6d49bf9038e2efd6a601 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 8.8E-72 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 HW35_16135 40d40184da3a6d3cabc346cd5c688011 346 Pfam PF14504 CAP-associated N-terminal 60 199 8.7E-48 T 12-10-2018 IPR029410 CAP-associated domain HW35_16135 40d40184da3a6d3cabc346cd5c688011 346 SUPERFAMILY SSF55797 223 341 6.28E-21 T 12-10-2018 IPR035940 CAP superfamily HW35_16135 40d40184da3a6d3cabc346cd5c688011 346 Pfam PF00188 Cysteine-rich secretory protein family 233 340 7.1E-15 T 12-10-2018 IPR014044 CAP domain HW35_16135 40d40184da3a6d3cabc346cd5c688011 346 Gene3D G3DSA:3.40.33.10 18 344 3.8E-103 T 12-10-2018 IPR035940 CAP superfamily HW35_16290 94101b4fda983a1574cdabaffde37bec 120 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 37 118 1.2E-19 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 HW35_16290 94101b4fda983a1574cdabaffde37bec 120 Pfam PF04977 Septum formation initiator 43 117 9.7E-12 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC HW35_16290 94101b4fda983a1574cdabaffde37bec 120 Hamap MF_00910 Cell division protein FtsL [ftsL]. 36 118 14.172 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 SMART SM00954 240 350 3.8E-70 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 Gene3D G3DSA:1.10.3210.10 1 196 1.0E-89 T 12-10-2018 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 Pfam PF02824 TGS domain 394 453 9.9E-23 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 Pfam PF13291 ACT domain 652 728 5.0E-22 T 12-10-2018 IPR002912 ACT domain HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 Gene3D G3DSA:3.30.460.10 198 329 1.2E-55 T 12-10-2018 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 SUPERFAMILY SSF55021 654 730 3.91E-13 T 12-10-2018 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 7.9E-40 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 Gene3D G3DSA:3.30.70.260 652 731 1.0E-18 T 12-10-2018 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 SUPERFAMILY SSF81301 185 398 4.25E-69 T 12-10-2018 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 Gene3D G3DSA:3.10.20.30 387 459 1.2E-32 T 12-10-2018 IPR012675 Beta-grasp domain superfamily HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 SUPERFAMILY SSF109604 10 196 3.11E-77 T 12-10-2018 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 SMART SM00471 46 158 9.1E-10 T 12-10-2018 IPR003607 HD/PDEase domain HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 728 2.4E-261 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 Pfam PF13328 HD domain 31 180 1.1E-52 T 12-10-2018 IPR003607 HD/PDEase domain HW35_04900 89a4357b38bf3a561cca073e419c0cbb 731 SUPERFAMILY SSF81271 381 453 1.96E-23 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 Gene3D G3DSA:3.40.50.1980 226 342 1.0E-126 T 12-10-2018 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 Gene3D G3DSA:3.40.50.1980 25 224 1.0E-126 T 12-10-2018 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 27 419 1.7E-167 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 222 254 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 PIRSF PIRSF000099 2 423 1.5E-170 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 420 42.6 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 PRINTS PR00083 Histidinol dehydrogenase signature 313 338 2.3E-89 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 PRINTS PR00083 Histidinol dehydrogenase signature 193 218 2.3E-89 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 PRINTS PR00083 Histidinol dehydrogenase signature 244 263 2.3E-89 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 PRINTS PR00083 Histidinol dehydrogenase signature 354 372 2.3E-89 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 PRINTS PR00083 Histidinol dehydrogenase signature 163 189 2.3E-89 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 PRINTS PR00083 Histidinol dehydrogenase signature 27 51 2.3E-89 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 PRINTS PR00083 Histidinol dehydrogenase signature 128 154 2.3E-89 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 PRINTS PR00083 Histidinol dehydrogenase signature 222 243 2.3E-89 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 SUPERFAMILY SSF53720 21 422 1.28E-86 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HW35_07660 52fbc06afd184c64bdc2b006a44181fa 427 Pfam PF00815 Histidinol dehydrogenase 19 420 2.5E-172 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HW35_17565 b4774630fa5708fb79d4f9b655c554ea 310 Gene3D G3DSA:1.10.3720.10 83 299 3.9E-23 T 12-10-2018 IPR035906 MetI-like superfamily HW35_17565 b4774630fa5708fb79d4f9b655c554ea 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 1.0E-40 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_17565 b4774630fa5708fb79d4f9b655c554ea 310 SUPERFAMILY SSF161098 88 286 1.8E-20 T 12-10-2018 IPR035906 MetI-like superfamily HW35_01910 cc1bf5aa4b77f1e30486338b291722c7 219 Pfam PF01569 PAP2 superfamily 90 207 1.4E-23 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HW35_01910 cc1bf5aa4b77f1e30486338b291722c7 219 SUPERFAMILY SSF48317 12 211 5.76E-41 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily HW35_01910 cc1bf5aa4b77f1e30486338b291722c7 219 SMART SM00014 90 202 5.5E-29 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HW35_01910 cc1bf5aa4b77f1e30486338b291722c7 219 Gene3D G3DSA:1.20.144.10 122 219 2.3E-27 T 12-10-2018 HW35_01910 cc1bf5aa4b77f1e30486338b291722c7 219 Gene3D G3DSA:1.20.144.10 8 121 2.1E-12 T 12-10-2018 HW35_16880 9978e750382c7ba6c107038998d42da9 299 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 6 123 2.2E-30 T 12-10-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal HW35_16880 9978e750382c7ba6c107038998d42da9 299 Gene3D G3DSA:3.40.50.720 126 272 3.4E-104 T 12-10-2018 HW35_16880 9978e750382c7ba6c107038998d42da9 299 Gene3D G3DSA:3.40.50.720 7 288 3.4E-104 T 12-10-2018 HW35_16880 9978e750382c7ba6c107038998d42da9 299 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 4 290 1.3E-138 T 12-10-2018 IPR014215 Dipicolinic acid synthetase subunit A HW35_16880 9978e750382c7ba6c107038998d42da9 299 SUPERFAMILY SSF51735 130 269 8.68E-19 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_16880 9978e750382c7ba6c107038998d42da9 299 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 151 290 2.4E-9 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HW35_01120 163f66d53dc28069139568bc9e40838c 139 Gene3D G3DSA:3.40.630.30 1 130 1.6E-29 T 12-10-2018 HW35_01120 163f66d53dc28069139568bc9e40838c 139 Pfam PF13673 Acetyltransferase (GNAT) domain 30 121 8.8E-13 T 12-10-2018 IPR000182 GNAT domain HW35_01120 163f66d53dc28069139568bc9e40838c 139 SUPERFAMILY SSF55729 10 126 5.93E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_11800 c87556d701103dbf303e6bf86afe8589 209 Pfam PF13241 Putative NAD(P)-binding 7 115 2.7E-27 T 12-10-2018 HW35_11800 c87556d701103dbf303e6bf86afe8589 209 SUPERFAMILY SSF51735 3 111 2.08E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_11800 c87556d701103dbf303e6bf86afe8589 209 SUPERFAMILY SSF75615 114 195 1.23E-16 T 12-10-2018 HW35_11800 c87556d701103dbf303e6bf86afe8589 209 Gene3D G3DSA:3.40.50.720 4 130 8.8E-42 T 12-10-2018 HW35_11800 c87556d701103dbf303e6bf86afe8589 209 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 5 186 5.1E-42 T 12-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 HW35_11800 c87556d701103dbf303e6bf86afe8589 209 Pfam PF14824 Sirohaem biosynthesis protein central 119 146 7.3E-8 T 12-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 HW35_11800 c87556d701103dbf303e6bf86afe8589 209 Gene3D G3DSA:1.10.8.610 131 204 7.6E-14 T 12-10-2018 HW35_17595 2b2b232dd60ccee47f84b4521438d114 302 Gene3D G3DSA:3.90.1720.10 170 302 3.3E-37 T 12-10-2018 HW35_17595 2b2b232dd60ccee47f84b4521438d114 302 SUPERFAMILY SSF54001 170 297 3.43E-39 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily HW35_17595 2b2b232dd60ccee47f84b4521438d114 302 Gene3D G3DSA:2.30.30.40 1 110 2.9E-40 T 12-10-2018 HW35_17595 2b2b232dd60ccee47f84b4521438d114 302 Pfam PF00877 NlpC/P60 family 188 295 9.4E-25 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain HW35_17595 2b2b232dd60ccee47f84b4521438d114 302 Gene3D G3DSA:2.30.30.40 112 169 1.6E-6 T 12-10-2018 HW35_16505 7044b590107b288027f0c626c9b885ce 210 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 210 30.457 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16505 7044b590107b288027f0c626c9b885ce 210 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 9 176 3.7E-50 T 12-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HW35_16505 7044b590107b288027f0c626c9b885ce 210 Gene3D G3DSA:3.40.50.2020 1 210 9.8E-65 T 12-10-2018 HW35_16505 7044b590107b288027f0c626c9b885ce 210 Pfam PF00156 Phosphoribosyl transferase domain 45 163 4.3E-18 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HW35_16505 7044b590107b288027f0c626c9b885ce 210 SUPERFAMILY SSF53271 7 207 4.85E-54 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_04645 6d3f6add205c2e10bca5898d7848d7a8 96 SUPERFAMILY SSF75471 1 94 1.31E-31 T 12-10-2018 IPR035920 YhbY-like superfamily HW35_04645 6d3f6add205c2e10bca5898d7848d7a8 96 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 3.0E-36 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 HW35_04645 6d3f6add205c2e10bca5898d7848d7a8 96 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 2.6E-23 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 HW35_04645 6d3f6add205c2e10bca5898d7848d7a8 96 SMART SM01103 2 85 8.3E-45 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 HW35_04645 6d3f6add205c2e10bca5898d7848d7a8 96 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 4.1E-41 T 12-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 HW35_04645 6d3f6add205c2e10bca5898d7848d7a8 96 Gene3D G3DSA:3.30.110.60 1 96 2.3E-38 T 12-10-2018 IPR035920 YhbY-like superfamily HW35_14680 61165ed70c6f21d22b427fd9e2382ee9 84 Pfam PF04226 Transglycosylase associated protein 33 78 1.0E-12 T 12-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 HW35_05595 b0e0417f736997085cd69e6681132a81 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 1.8E-69 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 HW35_05595 b0e0417f736997085cd69e6681132a81 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 84.947 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 HW35_05595 b0e0417f736997085cd69e6681132a81 153 Pfam PF03477 ATP cone domain 50 136 1.6E-20 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 HW35_15895 231d345cee052606457fa5c98d8b0d5c 233 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 171 199 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 HW35_15895 231d345cee052606457fa5c98d8b0d5c 233 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 1 84 1.7E-37 T 12-10-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 HW35_15895 231d345cee052606457fa5c98d8b0d5c 233 Gene3D G3DSA:2.160.10.10 82 233 2.5E-52 T 12-10-2018 HW35_15895 231d345cee052606457fa5c98d8b0d5c 233 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 232 45.518 T 12-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 HW35_15895 231d345cee052606457fa5c98d8b0d5c 233 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 3 233 1.5E-123 T 12-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 HW35_15895 231d345cee052606457fa5c98d8b0d5c 233 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 162 197 2.6E-11 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_15895 231d345cee052606457fa5c98d8b0d5c 233 Gene3D G3DSA:3.30.70.250 1 81 1.3E-36 T 12-10-2018 HW35_15895 231d345cee052606457fa5c98d8b0d5c 233 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 116 2.3E-5 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_15895 231d345cee052606457fa5c98d8b0d5c 233 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 153 7.7E-11 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_15895 231d345cee052606457fa5c98d8b0d5c 233 SUPERFAMILY SSF51161 85 222 7.57E-52 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily HW35_05700 9dee1d414f65eeb4172da38771dd99ed 293 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 4 286 38.285 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05700 9dee1d414f65eeb4172da38771dd99ed 293 Pfam PF01039 Carboxyl transferase domain 65 245 7.7E-19 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 HW35_05700 9dee1d414f65eeb4172da38771dd99ed 293 SUPERFAMILY SSF52096 33 287 7.11E-80 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_05700 9dee1d414f65eeb4172da38771dd99ed 293 Gene3D G3DSA:3.90.226.10 33 287 7.7E-88 T 12-10-2018 HW35_05700 9dee1d414f65eeb4172da38771dd99ed 293 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 21 287 1.9E-126 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05700 9dee1d414f65eeb4172da38771dd99ed 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 205 222 1.5E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05700 9dee1d414f65eeb4172da38771dd99ed 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 234 245 1.5E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05700 9dee1d414f65eeb4172da38771dd99ed 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 148 1.5E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05700 9dee1d414f65eeb4172da38771dd99ed 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 256 265 1.5E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_05700 9dee1d414f65eeb4172da38771dd99ed 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 168 186 1.5E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HW35_04265 55daa155f4867492de6e92879c908316 188 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 4 180 4.5E-55 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase HW35_04265 55daa155f4867492de6e92879c908316 188 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 4 180 3.3E-46 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase HW35_04265 55daa155f4867492de6e92879c908316 188 PIRSF PIRSF006806 1 184 1.0E-50 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase HW35_04265 55daa155f4867492de6e92879c908316 188 Gene3D G3DSA:3.40.50.10420 2 186 1.7E-61 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily HW35_04265 55daa155f4867492de6e92879c908316 188 SUPERFAMILY SSF100950 3 185 5.3E-49 T 12-10-2018 IPR037171 NagB/RpiA transferase-like HW35_05965 40488f49d10821f802670ae988f6c434 174 SUPERFAMILY SSF52972 1 167 1.87E-47 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HW35_05965 40488f49d10821f802670ae988f6c434 174 Pfam PF01931 Protein of unknown function DUF84 6 156 9.2E-48 T 12-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 HW35_05965 40488f49d10821f802670ae988f6c434 174 Hamap MF_00648 Non-canonical purine NTP phosphatase. 1 170 27.498 T 12-10-2018 IPR002786 Non-canonical purine NTP phosphatase HW35_05965 40488f49d10821f802670ae988f6c434 174 Gene3D G3DSA:3.90.950.10 1 174 1.1E-53 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HW35_03885 9f6739342f990b27929c598db456f7eb 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 3.3E-42 T 12-10-2018 IPR033248 Transketolase, C-terminal domain HW35_03885 9f6739342f990b27929c598db456f7eb 327 Gene3D G3DSA:3.40.50.920 193 327 3.0E-44 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HW35_03885 9f6739342f990b27929c598db456f7eb 327 SUPERFAMILY SSF52518 2 204 2.21E-74 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold HW35_03885 9f6739342f990b27929c598db456f7eb 327 SUPERFAMILY SSF52922 188 325 1.2E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HW35_03885 9f6739342f990b27929c598db456f7eb 327 SMART SM00861 4 179 3.9E-72 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HW35_03885 9f6739342f990b27929c598db456f7eb 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 4.3E-53 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HW35_03885 9f6739342f990b27929c598db456f7eb 327 Gene3D G3DSA:3.40.50.970 1 192 8.8E-94 T 12-10-2018 HW35_03735 0984e0186046ac3931308e3dce5b6031 199 Gene3D G3DSA:3.30.420.10 34 191 2.1E-14 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_03735 0984e0186046ac3931308e3dce5b6031 199 Pfam PF00665 Integrase core domain 37 151 3.4E-27 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_03735 0984e0186046ac3931308e3dce5b6031 199 SUPERFAMILY SSF53098 30 194 1.9E-34 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 SUPERFAMILY SSF54106 54 99 1.1E-8 T 12-10-2018 HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 SMART SM00636 106 404 3.2E-7 T 12-10-2018 IPR011583 Chitinase II GO:0008061 HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 Pfam PF01476 LysM domain 56 99 1.3E-9 T 12-10-2018 IPR018392 LysM domain HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 Pfam PF01476 LysM domain 4 47 2.0E-7 T 12-10-2018 IPR018392 LysM domain HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 SUPERFAMILY SSF51445 126 411 8.93E-37 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 Pfam PF00704 Glycosyl hydrolases family 18 186 401 2.4E-21 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 Gene3D G3DSA:3.10.50.10 321 375 2.9E-78 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 SUPERFAMILY SSF54106 2 47 4.97E-8 T 12-10-2018 HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 Gene3D G3DSA:3.10.350.10 2 54 4.3E-9 T 12-10-2018 IPR036779 LysM domain superfamily HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 Gene3D G3DSA:3.20.20.80 130 410 2.9E-78 T 12-10-2018 HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 SMART SM00257 55 99 1.6E-10 T 12-10-2018 IPR018392 LysM domain HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 SMART SM00257 3 47 4.7E-7 T 12-10-2018 IPR018392 LysM domain HW35_01985 a9fd2cef95c6599ea28abbb10b7b1ca9 421 Gene3D G3DSA:3.10.350.10 55 99 9.8E-15 T 12-10-2018 IPR036779 LysM domain superfamily HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 135 746 1.2E-160 T 12-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 132 207 9.6E-21 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 Gene3D G3DSA:3.20.70.20 62 754 2.9E-193 T 12-10-2018 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 616 638 - T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 287 306 1.7E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 500 523 1.7E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 538 560 1.7E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 627 654 1.7E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 448 459 1.7E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 566 589 1.7E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 Pfam PF02867 Ribonucleotide reductase, barrel domain 212 743 2.2E-130 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 SUPERFAMILY SSF51998 211 758 3.36E-151 T 12-10-2018 HW35_01905 fd81422b1a0778a5d1a0ec5bd82eb8ea 760 SUPERFAMILY SSF48168 5 210 8.89E-55 T 12-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_12285 aea9e9ea1c48c4d71155ea624fc2ac63 393 Pfam PF07670 Nucleoside recognition 91 188 8.8E-6 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HW35_12285 aea9e9ea1c48c4d71155ea624fc2ac63 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 1.1E-20 T 12-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 HW35_12285 aea9e9ea1c48c4d71155ea624fc2ac63 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 391 1.8E-60 T 12-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 HW35_09300 ba624f11b822a528eebe97b59e49ad1f 419 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 2.3E-47 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_09300 ba624f11b822a528eebe97b59e49ad1f 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 5.6E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_09300 ba624f11b822a528eebe97b59e49ad1f 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 5.6E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_09300 ba624f11b822a528eebe97b59e49ad1f 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 5.6E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_09300 ba624f11b822a528eebe97b59e49ad1f 419 SUPERFAMILY SSF56672 15 356 1.33E-62 T 12-10-2018 HW35_09300 ba624f11b822a528eebe97b59e49ad1f 419 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 5.1E-134 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_09300 ba624f11b822a528eebe97b59e49ad1f 419 Pfam PF08388 Group II intron, maturase-specific domain 288 360 6.7E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_04170 3e520ec3290f89984689ef7158afd3d2 60 Pfam PF14038 YqzE-like protein 2 51 2.4E-24 T 12-10-2018 IPR025622 YqzE-like protein HW35_11075 ad354a96cd3a485d1ac6b154ea236580 275 Hamap MF_01499 Diadenylate cyclase [dacA]. 1 254 34.901 T 12-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 HW35_11075 ad354a96cd3a485d1ac6b154ea236580 275 PIRSF PIRSF004793 4 270 5.2E-98 T 12-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 HW35_11075 ad354a96cd3a485d1ac6b154ea236580 275 Gene3D G3DSA:3.40.1700.10 102 255 1.2E-63 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily HW35_11075 ad354a96cd3a485d1ac6b154ea236580 275 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 4 255 3.8E-98 T 12-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 HW35_11075 ad354a96cd3a485d1ac6b154ea236580 275 SUPERFAMILY SSF143597 40 240 1.07E-72 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily HW35_11075 ad354a96cd3a485d1ac6b154ea236580 275 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 235 5.7E-45 T 12-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 SMART SM01192 141 429 9.8E-234 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 Gene3D G3DSA:3.30.390.10 3 129 1.7E-57 T 12-10-2018 IPR029017 Enolase-like, N-terminal HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 429 2.0E-220 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 SMART SM01193 4 136 1.0E-97 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 Hamap MF_00318 Enolase [eno]. 2 415 46.049 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 Pfam PF03952 Enolase, N-terminal domain 4 136 9.6E-61 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 SUPERFAMILY SSF54826 4 139 3.07E-60 T 12-10-2018 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 Pfam PF00113 Enolase, C-terminal TIM barrel domain 143 428 1.5E-144 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 PIRSF PIRSF001400 1 429 3.3E-195 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 PRINTS PR00148 Enolase signature 163 176 5.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 PRINTS PR00148 Enolase signature 367 384 5.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 PRINTS PR00148 Enolase signature 109 125 5.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 PRINTS PR00148 Enolase signature 37 51 5.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 PRINTS PR00148 Enolase signature 315 326 5.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 PRINTS PR00148 Enolase signature 338 352 5.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 Gene3D G3DSA:3.20.20.120 130 432 5.3E-142 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 ProSitePatterns PS00164 Enolase signature. 338 351 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HW35_07395 fe7e8648826833311ed4dfcc313eebb4 432 SUPERFAMILY SSF51604 141 430 3.96E-134 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily HW35_09355 b3d3dd57684113eb3a6706aa91de84e6 431 Pfam PF01966 HD domain 61 181 6.0E-17 T 12-10-2018 IPR006674 HD domain HW35_09355 b3d3dd57684113eb3a6706aa91de84e6 431 SMART SM00471 57 187 9.4E-12 T 12-10-2018 IPR003607 HD/PDEase domain HW35_09355 b3d3dd57684113eb3a6706aa91de84e6 431 Gene3D G3DSA:1.10.3210.10 11 401 1.1E-168 T 12-10-2018 HW35_09355 b3d3dd57684113eb3a6706aa91de84e6 431 Gene3D G3DSA:1.20.1250.30 235 412 1.1E-168 T 12-10-2018 HW35_09355 b3d3dd57684113eb3a6706aa91de84e6 431 SUPERFAMILY SSF109604 5 415 1.19E-125 T 12-10-2018 HW35_00045 5a6d3a84bc90e064735972fc878b1d32 66 PIRSF PIRSF002599 1 66 8.6E-25 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 HW35_00045 5a6d3a84bc90e064735972fc878b1d32 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.7E-30 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_00045 5a6d3a84bc90e064735972fc878b1d32 66 Gene3D G3DSA:2.40.50.140 1 65 1.1E-31 T 12-10-2018 HW35_00045 5a6d3a84bc90e064735972fc878b1d32 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site HW35_00045 5a6d3a84bc90e064735972fc878b1d32 66 PRINTS PR00050 Cold shock protein signature 4 19 3.4E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_00045 5a6d3a84bc90e064735972fc878b1d32 66 PRINTS PR00050 Cold shock protein signature 39 57 3.4E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_00045 5a6d3a84bc90e064735972fc878b1d32 66 PRINTS PR00050 Cold shock protein signature 24 33 3.4E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_00045 5a6d3a84bc90e064735972fc878b1d32 66 SMART SM00357 3 66 4.8E-29 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 HW35_00045 5a6d3a84bc90e064735972fc878b1d32 66 SUPERFAMILY SSF50249 1 65 1.18E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_14890 ab82ecc7f538a849ee94ecd00e187292 314 Gene3D G3DSA:2.40.50.140 24 98 1.1E-6 T 12-10-2018 HW35_14890 ab82ecc7f538a849ee94ecd00e187292 314 Pfam PF01966 HD domain 161 278 4.0E-11 T 12-10-2018 IPR006674 HD domain HW35_14890 ab82ecc7f538a849ee94ecd00e187292 314 SMART SM00471 156 288 1.1E-6 T 12-10-2018 IPR003607 HD/PDEase domain HW35_14890 ab82ecc7f538a849ee94ecd00e187292 314 Pfam PF01336 OB-fold nucleic acid binding domain 28 87 2.9E-6 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HW35_14890 ab82ecc7f538a849ee94ecd00e187292 314 SUPERFAMILY SSF109604 138 279 1.22E-15 T 12-10-2018 HW35_14890 ab82ecc7f538a849ee94ecd00e187292 314 Hamap MF_01427 3'-5' exoribonuclease YhaM [yhaM]. 1 313 62.896 T 12-10-2018 IPR020873 3'-5' exoribonuclease YhaM GO:0000175 HW35_14890 ab82ecc7f538a849ee94ecd00e187292 314 Gene3D G3DSA:1.10.3210.10 122 293 5.4E-12 T 12-10-2018 HW35_14890 ab82ecc7f538a849ee94ecd00e187292 314 SUPERFAMILY SSF50249 31 96 1.16E-6 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_13140 260985424417a03f7939e78692dbd0a5 272 SUPERFAMILY SSF161098 3 272 2.62E-66 T 12-10-2018 IPR035906 MetI-like superfamily HW35_13140 260985424417a03f7939e78692dbd0a5 272 Gene3D G3DSA:1.10.3720.10 1 260 1.5E-58 T 12-10-2018 IPR035906 MetI-like superfamily HW35_13140 260985424417a03f7939e78692dbd0a5 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 266 3.3E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_02105 31d21ee8fb7f4b61a265175974fb4c5a 250 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 242 1.3E-18 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase HW35_02105 31d21ee8fb7f4b61a265175974fb4c5a 250 Gene3D G3DSA:3.60.10.10 1 249 8.0E-94 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily HW35_02105 31d21ee8fb7f4b61a265175974fb4c5a 250 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 250 1.1E-95 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 HW35_02105 31d21ee8fb7f4b61a265175974fb4c5a 250 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 249 5.0E-92 T 12-10-2018 HW35_02105 31d21ee8fb7f4b61a265175974fb4c5a 250 SUPERFAMILY SSF56219 1 250 8.9E-80 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily HW35_02105 31d21ee8fb7f4b61a265175974fb4c5a 250 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 12-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 HW35_00900 0aac4b6ee2b0ebc9a0480a733df8d0cf 434 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 6 415 1.7E-140 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 HW35_00900 0aac4b6ee2b0ebc9a0480a733df8d0cf 434 TIGRFAM TIGR03173 pbuX: xanthine permease 11 417 7.2E-167 T 12-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 HW35_00900 0aac4b6ee2b0ebc9a0480a733df8d0cf 434 Pfam PF00860 Permease family 7 385 2.4E-118 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 HW35_00900 0aac4b6ee2b0ebc9a0480a733df8d0cf 434 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 332 352 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 HW35_12890 1e624108109c768b00759c3e11b1dad1 161 TIGRFAM TIGR01753 flav_short: flavodoxin 3 142 2.6E-42 T 12-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 HW35_12890 1e624108109c768b00759c3e11b1dad1 161 SUPERFAMILY SSF52218 1 146 2.18E-36 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_12890 1e624108109c768b00759c3e11b1dad1 161 Gene3D G3DSA:3.40.50.360 1 145 6.9E-34 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_12890 1e624108109c768b00759c3e11b1dad1 161 Pfam PF00258 Flavodoxin 5 136 7.0E-23 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 HW35_11455 79b65be13cdfc31e1c38709fdd293db2 157 Pfam PF17283 SprT-like zinc ribbon domain 119 149 2.2E-7 T 12-10-2018 IPR035240 SprT-like, zinc ribbon domain HW35_11455 79b65be13cdfc31e1c38709fdd293db2 157 Pfam PF10263 SprT-like family 15 97 5.2E-11 T 12-10-2018 IPR006640 SprT-like HW35_11455 79b65be13cdfc31e1c38709fdd293db2 157 Hamap MF_00745 Protein SprT-like. 4 151 39.045 T 12-10-2018 IPR023524 Uncharacterised protein family SprT-like HW35_11455 79b65be13cdfc31e1c38709fdd293db2 157 SMART SM00731 4 151 4.0E-50 T 12-10-2018 IPR006640 SprT-like HW35_01510 8242727559d4d797245ccc46437c65b6 93 SUPERFAMILY SSF46689 5 90 3.4E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_01510 8242727559d4d797245ccc46437c65b6 93 Pfam PF01527 Transposase 3 73 6.6E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_01510 8242727559d4d797245ccc46437c65b6 93 Gene3D G3DSA:1.10.10.60 9 87 2.9E-9 T 12-10-2018 HW35_11170 8242727559d4d797245ccc46437c65b6 93 SUPERFAMILY SSF46689 5 90 3.4E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_11170 8242727559d4d797245ccc46437c65b6 93 Pfam PF01527 Transposase 3 73 6.6E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_11170 8242727559d4d797245ccc46437c65b6 93 Gene3D G3DSA:1.10.10.60 9 87 2.9E-9 T 12-10-2018 HW35_12210 8a6b1db9d2ac7c92b36fd021352758f1 261 PIRSF PIRSF033101 1 258 3.9E-62 T 12-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 HW35_12210 8a6b1db9d2ac7c92b36fd021352758f1 261 Pfam PF10086 Putative membrane peptidase family (DUF2324) 17 236 2.6E-56 T 12-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 HW35_10235 7908cdd63587a402454723b813240979 59 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 11 54 4.4E-6 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 HW35_10235 7908cdd63587a402454723b813240979 59 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HW35_02560 0322f76e1268505bef8d2be13312f6eb 341 Pfam PF00591 Glycosyl transferase family, a/b domain 73 323 2.0E-90 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_02560 0322f76e1268505bef8d2be13312f6eb 341 SUPERFAMILY SSF52418 73 335 6.15E-90 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_02560 0322f76e1268505bef8d2be13312f6eb 341 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 331 3.0E-116 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 HW35_02560 0322f76e1268505bef8d2be13312f6eb 341 SUPERFAMILY SSF47648 1 66 7.33E-15 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_02560 0322f76e1268505bef8d2be13312f6eb 341 Gene3D G3DSA:1.20.970.10 4 66 8.2E-17 T 12-10-2018 HW35_02560 0322f76e1268505bef8d2be13312f6eb 341 Gene3D G3DSA:3.40.1030.10 69 340 1.9E-101 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_02560 0322f76e1268505bef8d2be13312f6eb 341 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 332 36.931 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 HW35_02560 0322f76e1268505bef8d2be13312f6eb 341 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 61 4.5E-14 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_13165 1ce323abc213d16d1add600423192f87 322 Gene3D G3DSA:3.20.20.150 1 315 1.0E-69 T 12-10-2018 HW35_13165 1ce323abc213d16d1add600423192f87 322 SUPERFAMILY SSF51658 2 310 1.06E-49 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily HW35_13165 1ce323abc213d16d1add600423192f87 322 Pfam PF01261 Xylose isomerase-like TIM barrel 20 231 7.5E-28 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HW35_13165 1ce323abc213d16d1add600423192f87 322 Pfam PF07582 AP endonuclease family 2 C terminus 268 322 7.7E-23 T 12-10-2018 IPR011418 AP endonuclease, family 2, C-terminal HW35_03745 e44740b30af6865c8e38e4e56e33697a 184 SUPERFAMILY SSF55811 7 178 4.33E-51 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 HW35_03745 e44740b30af6865c8e38e4e56e33697a 184 Gene3D G3DSA:3.90.79.10 4 183 5.7E-57 T 12-10-2018 HW35_03745 e44740b30af6865c8e38e4e56e33697a 184 Pfam PF00293 NUDIX domain 42 157 3.1E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HW35_03745 e44740b30af6865c8e38e4e56e33697a 184 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HW35_03745 e44740b30af6865c8e38e4e56e33697a 184 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 2 177 5.0E-26 T 12-10-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 HW35_15675 bc41d1d0d7f39c99be0f6b1fec28fb6e 390 SUPERFAMILY SSF53383 6 386 6.05E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_15675 bc41d1d0d7f39c99be0f6b1fec28fb6e 390 Gene3D G3DSA:3.40.640.10 45 286 5.7E-120 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_15675 bc41d1d0d7f39c99be0f6b1fec28fb6e 390 Gene3D G3DSA:3.90.1150.10 30 384 5.7E-120 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_15675 bc41d1d0d7f39c99be0f6b1fec28fb6e 390 Pfam PF00155 Aminotransferase class I and II 34 384 5.4E-68 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HW35_01620 7e9c8e5a4504b22086673cc63219eb71 123 Gene3D G3DSA:1.10.10.10 1 109 9.1E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_01620 7e9c8e5a4504b22086673cc63219eb71 123 Pfam PF01638 HxlR-like helix-turn-helix 16 104 1.7E-39 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type HW35_01620 7e9c8e5a4504b22086673cc63219eb71 123 SUPERFAMILY SSF46785 2 109 4.82E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_02125 b9283b57cb153ad78d43a54f6e8c80de 619 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 9 617 4.0E-134 T 12-10-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 HW35_02125 b9283b57cb153ad78d43a54f6e8c80de 619 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 304 617 2.9E-86 T 12-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 HW35_02125 b9283b57cb153ad78d43a54f6e8c80de 619 SUPERFAMILY SSF48239 35 291 5.23E-47 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid HW35_02125 b9283b57cb153ad78d43a54f6e8c80de 619 SUPERFAMILY SSF48239 296 618 1.49E-81 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid HW35_02125 b9283b57cb153ad78d43a54f6e8c80de 619 Gene3D G3DSA:1.50.10.20 13 615 8.8E-205 T 12-10-2018 HW35_02125 b9283b57cb153ad78d43a54f6e8c80de 619 Gene3D G3DSA:1.50.10.20 29 301 8.8E-205 T 12-10-2018 HW35_02125 b9283b57cb153ad78d43a54f6e8c80de 619 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 12 617 8.4E-124 T 12-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 HW35_02125 b9283b57cb153ad78d43a54f6e8c80de 619 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 13 290 1.9E-78 T 12-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 HW35_10070 0c1dbb498b0a8fb9951fd1115d49a1f3 231 Pfam PF01712 Deoxynucleoside kinase 3 219 3.4E-40 T 12-10-2018 IPR031314 Deoxynucleoside kinase domain HW35_10070 0c1dbb498b0a8fb9951fd1115d49a1f3 231 PIRSF PIRSF000705 1 226 3.5E-42 T 12-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 HW35_10070 0c1dbb498b0a8fb9951fd1115d49a1f3 231 SUPERFAMILY SSF52540 3 219 2.38E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10070 0c1dbb498b0a8fb9951fd1115d49a1f3 231 Gene3D G3DSA:3.40.50.300 2 222 5.2E-49 T 12-10-2018 HW35_13110 ba514f757abe82751173c2a7934a312b 174 Gene3D G3DSA:1.20.120.450 23 169 4.9E-31 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes HW35_13110 ba514f757abe82751173c2a7934a312b 174 Pfam PF12867 DinB superfamily 30 164 9.8E-17 T 12-10-2018 IPR024775 DinB-like domain HW35_13110 ba514f757abe82751173c2a7934a312b 174 SUPERFAMILY SSF109854 8 166 8.39E-31 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes HW35_17440 a0ea65b39aba4acd6ff6606b2a827942 199 Gene3D G3DSA:3.40.50.300 3 199 6.4E-82 T 12-10-2018 HW35_17440 a0ea65b39aba4acd6ff6606b2a827942 199 Pfam PF01583 Adenylylsulphate kinase 26 180 7.6E-71 T 12-10-2018 HW35_17440 a0ea65b39aba4acd6ff6606b2a827942 199 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 25 197 38.519 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HW35_17440 a0ea65b39aba4acd6ff6606b2a827942 199 SUPERFAMILY SSF52540 22 195 6.57E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17440 a0ea65b39aba4acd6ff6606b2a827942 199 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 9 193 1.7E-84 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HW35_17010 c4c3032f2c5e3a6db0f0b70ac5bd31a8 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 129 147 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_17010 c4c3032f2c5e3a6db0f0b70ac5bd31a8 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 61 74 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_17010 c4c3032f2c5e3a6db0f0b70ac5bd31a8 419 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 187 200 7.4E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HW35_17010 c4c3032f2c5e3a6db0f0b70ac5bd31a8 419 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 10 353 1.7E-134 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase HW35_17010 c4c3032f2c5e3a6db0f0b70ac5bd31a8 419 SUPERFAMILY SSF56672 15 356 6.12E-63 T 12-10-2018 HW35_17010 c4c3032f2c5e3a6db0f0b70ac5bd31a8 419 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 272 1.1E-47 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_17010 c4c3032f2c5e3a6db0f0b70ac5bd31a8 419 Pfam PF08388 Group II intron, maturase-specific domain 288 360 6.7E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_12435 07db5eddbe9dd34a171af992c4dc22f0 255 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 43.325 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 HW35_12435 07db5eddbe9dd34a171af992c4dc22f0 255 SUPERFAMILY SSF110399 1 240 4.05E-85 T 12-10-2018 HW35_12435 07db5eddbe9dd34a171af992c4dc22f0 255 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 248 1.3E-112 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 HW35_12435 07db5eddbe9dd34a171af992c4dc22f0 255 Gene3D G3DSA:3.20.20.70 1 254 2.7E-119 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_10175 575fbb167cf07165f6970eda9cbe8ea7 247 Pfam PF05175 Methyltransferase small domain 18 126 2.8E-9 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 HW35_10175 575fbb167cf07165f6970eda9cbe8ea7 247 Gene3D G3DSA:3.40.50.150 8 247 1.3E-72 T 12-10-2018 HW35_10175 575fbb167cf07165f6970eda9cbe8ea7 247 SUPERFAMILY SSF53335 16 198 1.18E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_10215 f865da08c6721831ee402d492cb8c55f 187 SMART SM00493 4 77 2.7E-9 T 12-10-2018 IPR006171 TOPRIM domain HW35_10215 f865da08c6721831ee402d492cb8c55f 187 Hamap MF_01469 Ribonuclease M5 [rnmV]. 3 178 33.193 T 12-10-2018 IPR004466 Ribonuclease M5 GO:0043822 HW35_10215 f865da08c6721831ee402d492cb8c55f 187 SUPERFAMILY SSF110455 1 115 1.41E-37 T 12-10-2018 HW35_10215 f865da08c6721831ee402d492cb8c55f 187 Gene3D G3DSA:3.40.1360.20 1 120 2.1E-27 T 12-10-2018 HW35_10215 f865da08c6721831ee402d492cb8c55f 187 Pfam PF13331 Domain of unknown function (DUF4093) 93 176 2.0E-30 T 12-10-2018 IPR025156 Ribonuclease M5, C-terminal domain HW35_10215 f865da08c6721831ee402d492cb8c55f 187 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 176 2.3E-62 T 12-10-2018 IPR004466 Ribonuclease M5 GO:0043822 HW35_10215 f865da08c6721831ee402d492cb8c55f 187 Pfam PF13662 Toprim domain 5 71 3.3E-8 T 12-10-2018 IPR006171 TOPRIM domain HW35_01980 0419ed17c85687b046247bb7d2c78ddc 500 Gene3D G3DSA:3.50.80.20 110 202 1.4E-25 T 12-10-2018 HW35_01980 0419ed17c85687b046247bb7d2c78ddc 500 Gene3D G3DSA:3.40.710.10 292 499 5.5E-56 T 12-10-2018 HW35_01980 0419ed17c85687b046247bb7d2c78ddc 500 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 73 479 1.6E-130 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_01980 0419ed17c85687b046247bb7d2c78ddc 500 SUPERFAMILY SSF56601 55 498 2.6E-98 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_01980 0419ed17c85687b046247bb7d2c78ddc 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 389 403 1.4E-30 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_01980 0419ed17c85687b046247bb7d2c78ddc 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 86 105 1.4E-30 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_01980 0419ed17c85687b046247bb7d2c78ddc 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 456 469 1.4E-30 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_01980 0419ed17c85687b046247bb7d2c78ddc 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 374 388 1.4E-30 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_01980 0419ed17c85687b046247bb7d2c78ddc 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 317 339 1.4E-30 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_01980 0419ed17c85687b046247bb7d2c78ddc 500 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 48 496 3.6E-141 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HW35_16455 337ca2cef6b1c0d8c8a41cf521f79456 180 SUPERFAMILY SSF53271 6 174 7.34E-42 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_16455 337ca2cef6b1c0d8c8a41cf521f79456 180 Pfam PF00156 Phosphoribosyl transferase domain 7 155 2.2E-20 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HW35_16455 337ca2cef6b1c0d8c8a41cf521f79456 180 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 179 38.583 T 12-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 HW35_16455 337ca2cef6b1c0d8c8a41cf521f79456 180 Gene3D G3DSA:3.40.50.2020 1 180 3.4E-62 T 12-10-2018 HW35_02135 8664b0910d7fb2906cc84270edbeab7c 231 SUPERFAMILY SSF52172 2 124 6.26E-38 T 12-10-2018 IPR011006 CheY-like superfamily HW35_02135 8664b0910d7fb2906cc84270edbeab7c 231 Gene3D G3DSA:3.40.50.2300 1 125 1.3E-34 T 12-10-2018 HW35_02135 8664b0910d7fb2906cc84270edbeab7c 231 SMART SM00448 1 112 3.4E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_02135 8664b0910d7fb2906cc84270edbeab7c 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 224 2.0E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_02135 8664b0910d7fb2906cc84270edbeab7c 231 SUPERFAMILY SSF46894 125 225 1.08E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_02135 8664b0910d7fb2906cc84270edbeab7c 231 Pfam PF00072 Response regulator receiver domain 3 113 6.6E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_02135 8664b0910d7fb2906cc84270edbeab7c 231 Gene3D G3DSA:1.10.10.10 129 231 2.7E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_02135 8664b0910d7fb2906cc84270edbeab7c 231 SMART SM00862 149 224 2.3E-30 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_11830 a6b4d50f604c4136f9637b0edc0c0473 475 SMART SM00845 325 472 1.5E-84 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 HW35_11830 a6b4d50f604c4136f9637b0edc0c0473 475 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 141 155 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 HW35_11830 a6b4d50f604c4136f9637b0edc0c0473 475 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 472 5.9E-184 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 HW35_11830 a6b4d50f604c4136f9637b0edc0c0473 475 Gene3D G3DSA:1.10.10.410 412 475 1.6E-28 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal HW35_11830 a6b4d50f604c4136f9637b0edc0c0473 475 Pfam PF02934 GatB/GatE catalytic domain 5 285 8.4E-114 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 HW35_11830 a6b4d50f604c4136f9637b0edc0c0473 475 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 473 39.724 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 HW35_11830 a6b4d50f604c4136f9637b0edc0c0473 475 SUPERFAMILY SSF89095 294 399 1.74E-36 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 HW35_11830 a6b4d50f604c4136f9637b0edc0c0473 475 Gene3D G3DSA:1.10.150.380 297 410 2.8E-39 T 12-10-2018 HW35_11830 a6b4d50f604c4136f9637b0edc0c0473 475 SUPERFAMILY SSF55931 4 293 1.96E-124 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 HW35_11830 a6b4d50f604c4136f9637b0edc0c0473 475 Pfam PF02637 GatB domain 325 472 6.1E-59 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 HW35_11805 5865354252a518b5cb6a8bed9352632f 427 Gene3D G3DSA:3.20.20.60 5 406 3.4E-175 T 12-10-2018 HW35_11805 5865354252a518b5cb6a8bed9352632f 427 PIRSF PIRSF001362 1 426 1.1E-242 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 HW35_11805 5865354252a518b5cb6a8bed9352632f 427 ProSitePatterns PS00161 Isocitrate lyase signature. 184 189 - T 12-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 HW35_11805 5865354252a518b5cb6a8bed9352632f 427 SUPERFAMILY SSF51621 8 423 1.17E-158 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 HW35_11805 5865354252a518b5cb6a8bed9352632f 427 Pfam PF00463 Isocitrate lyase family 6 250 6.2E-60 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 HW35_11805 5865354252a518b5cb6a8bed9352632f 427 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 7 246 3.2E-106 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 HW35_12360 d0cbc29286a05e41ea0b27749c02c671 438 Pfam PF00202 Aminotransferase class-III 24 425 2.5E-126 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_12360 d0cbc29286a05e41ea0b27749c02c671 438 Gene3D G3DSA:3.90.1150.10 12 422 7.5E-149 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_12360 d0cbc29286a05e41ea0b27749c02c671 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 242 279 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_12360 d0cbc29286a05e41ea0b27749c02c671 438 PIRSF PIRSF000521 18 128 2.8E-6 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_12360 d0cbc29286a05e41ea0b27749c02c671 438 PIRSF PIRSF000521 121 429 3.0E-43 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_12360 d0cbc29286a05e41ea0b27749c02c671 438 SUPERFAMILY SSF53383 20 428 1.69E-127 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_12360 d0cbc29286a05e41ea0b27749c02c671 438 Gene3D G3DSA:3.40.640.10 58 325 7.5E-149 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_00120 fe7959138a77a420d91208c2526ec218 262 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 262 35.546 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 HW35_00120 fe7959138a77a420d91208c2526ec218 262 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 11 249 2.7E-43 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 HW35_00120 fe7959138a77a420d91208c2526ec218 262 Pfam PF02654 Cobalamin-5-phosphate synthase 11 249 1.5E-49 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 HW35_06135 89a64f0320d59001af5c3dfeaa8b2364 320 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 15 314 1.2E-136 T 12-10-2018 IPR005911 Protein YhcC-like GO:0051536 HW35_06135 89a64f0320d59001af5c3dfeaa8b2364 320 SMART SM00729 32 259 4.3E-41 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HW35_06135 89a64f0320d59001af5c3dfeaa8b2364 320 SUPERFAMILY SSF102114 6 313 4.84E-55 T 12-10-2018 HW35_06135 89a64f0320d59001af5c3dfeaa8b2364 320 Gene3D G3DSA:3.80.30.20 51 252 3.7E-13 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HW35_06135 89a64f0320d59001af5c3dfeaa8b2364 320 Pfam PF16199 Radical_SAM C-terminal domain 220 303 1.4E-25 T 12-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 HW35_06135 89a64f0320d59001af5c3dfeaa8b2364 320 Pfam PF04055 Radical SAM superfamily 52 214 7.5E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 15 131 9.5E-28 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 SUPERFAMILY SSF53223 4 143 1.95E-49 T 12-10-2018 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 Gene3D G3DSA:3.40.50.720 134 336 6.8E-156 T 12-10-2018 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 SUPERFAMILY SSF51735 141 347 1.13E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 PIRSF PIRSF000188 1 353 5.7E-170 T 12-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 148 200 3.7E-6 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 217 343 2.5E-10 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 Gene3D G3DSA:3.40.50.10860 10 343 6.8E-156 T 12-10-2018 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 1.3E-22 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 1.3E-22 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 1.3E-22 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 1.3E-22 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_03905 17e593fc5733c7fe5677e2bc966fc1f1 367 SMART SM00839 144 351 5.8E-75 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HW35_02670 6469100a1508b1e44c14b4afe6f81ff7 234 SUPERFAMILY SSF53167 2 232 3.01E-90 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 HW35_02670 6469100a1508b1e44c14b4afe6f81ff7 234 Gene3D G3DSA:3.40.50.1580 1 234 2.5E-71 T 12-10-2018 HW35_02670 6469100a1508b1e44c14b4afe6f81ff7 234 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 12-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 HW35_02670 6469100a1508b1e44c14b4afe6f81ff7 234 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 231 9.7E-109 T 12-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 HW35_02670 6469100a1508b1e44c14b4afe6f81ff7 234 Pfam PF01048 Phosphorylase superfamily 16 217 7.2E-40 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HW35_02670 6469100a1508b1e44c14b4afe6f81ff7 234 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 233 47.441 T 12-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 HW35_09935 a295809f5b0ed76388eb4791bd7177e7 238 SUPERFAMILY SSF53335 1 237 3.08E-47 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_09935 a295809f5b0ed76388eb4791bd7177e7 238 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 28.302 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HW35_09935 a295809f5b0ed76388eb4791bd7177e7 238 Pfam PF02527 rRNA small subunit methyltransferase G 21 197 2.1E-56 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HW35_09935 a295809f5b0ed76388eb4791bd7177e7 238 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 217 1.6E-50 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HW35_09935 a295809f5b0ed76388eb4791bd7177e7 238 PIRSF PIRSF003078 1 220 1.3E-56 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HW35_09935 a295809f5b0ed76388eb4791bd7177e7 238 Gene3D G3DSA:3.40.50.150 1 238 1.9E-87 T 12-10-2018 HW35_05805 58d5fbac733dc53aaa3f45928fc7136e 166 SUPERFAMILY SSF52833 1 160 5.1E-45 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_05805 58d5fbac733dc53aaa3f45928fc7136e 166 Pfam PF08534 Redoxin 19 159 2.9E-23 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 HW35_05805 58d5fbac733dc53aaa3f45928fc7136e 166 Gene3D G3DSA:3.40.30.10 1 166 3.9E-50 T 12-10-2018 HW35_05805 58d5fbac733dc53aaa3f45928fc7136e 166 Hamap MF_00269 Thiol peroxidase [tpx]. 3 163 38.74 T 12-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 HW35_05805 58d5fbac733dc53aaa3f45928fc7136e 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 12-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 HW35_03535 c0271d08c348ba4734855ddcd9c14382 252 Gene3D G3DSA:2.70.70.10 25 164 3.7E-41 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_03535 c0271d08c348ba4734855ddcd9c14382 252 Pfam PF01551 Peptidase family M23 60 153 2.9E-31 T 12-10-2018 IPR016047 Peptidase M23 HW35_03535 c0271d08c348ba4734855ddcd9c14382 252 SUPERFAMILY SSF51261 31 163 9.42E-47 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_03535 c0271d08c348ba4734855ddcd9c14382 252 SMART SM00257 209 252 1.0E-13 T 12-10-2018 IPR018392 LysM domain HW35_03535 c0271d08c348ba4734855ddcd9c14382 252 Gene3D G3DSA:3.10.350.10 204 252 2.5E-15 T 12-10-2018 IPR036779 LysM domain superfamily HW35_03535 c0271d08c348ba4734855ddcd9c14382 252 SUPERFAMILY SSF54106 209 251 8.24E-11 T 12-10-2018 HW35_03535 c0271d08c348ba4734855ddcd9c14382 252 Pfam PF01476 LysM domain 210 251 6.5E-14 T 12-10-2018 IPR018392 LysM domain HW35_06255 433283e86de6f6c5612af22976e69a6d 273 Pfam PF13276 HTH-like domain 29 76 7.6E-20 T 12-10-2018 IPR025948 HTH-like domain HW35_06255 433283e86de6f6c5612af22976e69a6d 273 Pfam PF00665 Integrase core domain 109 223 5.2E-24 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_06255 433283e86de6f6c5612af22976e69a6d 273 Gene3D G3DSA:3.30.420.10 99 271 1.2E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_06255 433283e86de6f6c5612af22976e69a6d 273 SUPERFAMILY SSF53098 100 263 1.12E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_15910 a2f882235145ed3b247e36d998e6ff02 442 Pfam PF00665 Integrase core domain 280 395 1.5E-21 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_15910 a2f882235145ed3b247e36d998e6ff02 442 Pfam PF13276 HTH-like domain 195 250 5.9E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_15910 a2f882235145ed3b247e36d998e6ff02 442 Gene3D G3DSA:3.30.420.10 275 439 1.4E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_15910 a2f882235145ed3b247e36d998e6ff02 442 SUPERFAMILY SSF53098 272 437 2.28E-28 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_15420 056a57635d64ed722c520cbc5adeab09 167 Pfam PF14153 Spore coat protein CotO 42 164 3.0E-19 T 12-10-2018 IPR025439 Spore coat protein CotO HW35_12575 8547f830e31ca522be5d170eecfc1843 132 SUPERFAMILY SSF55811 2 130 3.25E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 HW35_12575 8547f830e31ca522be5d170eecfc1843 132 Gene3D G3DSA:3.90.79.10 1 132 2.4E-30 T 12-10-2018 HW35_12575 8547f830e31ca522be5d170eecfc1843 132 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HW35_12575 8547f830e31ca522be5d170eecfc1843 132 Pfam PF00293 NUDIX domain 6 124 3.7E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HW35_01890 544d679d6b4bcd563e93fbd99208f286 441 SUPERFAMILY SSF56176 33 208 8.51E-50 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 HW35_01890 544d679d6b4bcd563e93fbd99208f286 441 Pfam PF01565 FAD binding domain 34 171 2.3E-33 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HW35_01890 544d679d6b4bcd563e93fbd99208f286 441 Gene3D G3DSA:3.30.465.40 2 218 3.5E-55 T 12-10-2018 HW35_01890 544d679d6b4bcd563e93fbd99208f286 441 SUPERFAMILY SSF55103 212 438 1.06E-18 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HW35_13810 010ce087902911c1a5eecd37bac33ddc 114 SUPERFAMILY SSF46785 3 92 6.37E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13810 010ce087902911c1a5eecd37bac33ddc 114 Gene3D G3DSA:1.10.10.10 1 99 7.6E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_13810 010ce087902911c1a5eecd37bac33ddc 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 2.5E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_13810 010ce087902911c1a5eecd37bac33ddc 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 45 2.5E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_13810 010ce087902911c1a5eecd37bac33ddc 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 2.5E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_13810 010ce087902911c1a5eecd37bac33ddc 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 2.5E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_13810 010ce087902911c1a5eecd37bac33ddc 114 SMART SM00418 13 92 1.4E-24 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_13810 010ce087902911c1a5eecd37bac33ddc 114 Pfam PF01022 Bacterial regulatory protein, arsR family 20 65 5.7E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HW35_05860 cab17b0545d26e9c2b372561b4a3c790 559 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 1 559 21.456 T 12-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 HW35_05860 cab17b0545d26e9c2b372561b4a3c790 559 Pfam PF06160 Septation ring formation regulator, EzrA 3 557 6.3E-176 T 12-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 HW35_16325 7a36bfde0602696062f58a2a8be2337d 366 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 322 346 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16325 7a36bfde0602696062f58a2a8be2337d 366 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 9 362 5.5E-180 T 12-10-2018 IPR013438 Sporulation stage V, protein E HW35_16325 7a36bfde0602696062f58a2a8be2337d 366 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 9 363 1.1E-133 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16325 7a36bfde0602696062f58a2a8be2337d 366 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 9 362 2.2E-101 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16325 7a36bfde0602696062f58a2a8be2337d 366 Pfam PF01098 Cell cycle protein 12 365 1.9E-128 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_08640 841adfa17bb8fe4697de32005a0e35d9 442 Pfam PF02754 Cysteine-rich domain 198 279 2.9E-20 T 12-10-2018 IPR004017 Cysteine-rich domain HW35_08640 841adfa17bb8fe4697de32005a0e35d9 442 Pfam PF02754 Cysteine-rich domain 329 414 8.4E-13 T 12-10-2018 IPR004017 Cysteine-rich domain HW35_08640 841adfa17bb8fe4697de32005a0e35d9 442 Pfam PF13183 4Fe-4S dicluster domain 23 92 1.6E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HW35_08640 841adfa17bb8fe4697de32005a0e35d9 442 Gene3D G3DSA:1.10.1060.10 1 112 6.4E-9 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HW35_08640 841adfa17bb8fe4697de32005a0e35d9 442 PIRSF PIRSF000139 6 441 1.0E-138 T 12-10-2018 HW35_08640 841adfa17bb8fe4697de32005a0e35d9 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 78 89 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_08640 841adfa17bb8fe4697de32005a0e35d9 442 SUPERFAMILY SSF46548 16 107 1.12E-18 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HW35_16335 3129be3cbaf9acc05cf94fc93bf8c295 302 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 299 3.1E-29 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_16335 3129be3cbaf9acc05cf94fc93bf8c295 302 Gene3D G3DSA:3.90.78.10 217 302 1.7E-34 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_16335 3129be3cbaf9acc05cf94fc93bf8c295 302 Pfam PF01565 FAD binding domain 35 165 4.9E-24 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HW35_16335 3129be3cbaf9acc05cf94fc93bf8c295 302 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 300 5.6E-103 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_16335 3129be3cbaf9acc05cf94fc93bf8c295 302 Gene3D G3DSA:3.30.43.10 1 88 4.1E-30 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 HW35_16335 3129be3cbaf9acc05cf94fc93bf8c295 302 SUPERFAMILY SSF56194 196 300 4.58E-37 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_16335 3129be3cbaf9acc05cf94fc93bf8c295 302 Gene3D G3DSA:3.30.465.10 89 216 1.6E-47 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 HW35_16335 3129be3cbaf9acc05cf94fc93bf8c295 302 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 302 89.625 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_16335 3129be3cbaf9acc05cf94fc93bf8c295 302 SUPERFAMILY SSF56176 14 194 4.49E-43 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 6.1E-59 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 6.1E-59 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 6.1E-59 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 6.1E-59 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 6.1E-59 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 Gene3D G3DSA:3.90.640.10 178 251 4.8E-129 T 12-10-2018 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 SUPERFAMILY SSF53067 3 140 3.02E-39 T 12-10-2018 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 SUPERFAMILY SSF53067 142 324 1.49E-49 T 12-10-2018 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 Gene3D G3DSA:3.30.420.40 146 309 4.8E-129 T 12-10-2018 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 Pfam PF06723 MreB/Mbl protein 4 326 1.6E-151 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 Gene3D G3DSA:3.30.420.40 6 319 4.8E-129 T 12-10-2018 HW35_08965 9c586878298831c6a3d4b997eb7d5013 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 327 1.3E-138 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HW35_02545 d20c0458996aeebc9a4c011f1262fc73 404 Gene3D G3DSA:3.40.50.1100 14 210 2.7E-194 T 12-10-2018 HW35_02545 d20c0458996aeebc9a4c011f1262fc73 404 PIRSF PIRSF001413 2 401 5.3E-170 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HW35_02545 d20c0458996aeebc9a4c011f1262fc73 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 382 5.5E-50 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HW35_02545 d20c0458996aeebc9a4c011f1262fc73 404 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 11 393 2.7E-196 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HW35_02545 d20c0458996aeebc9a4c011f1262fc73 404 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 6 395 53.953 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HW35_02545 d20c0458996aeebc9a4c011f1262fc73 404 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 85 99 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HW35_02545 d20c0458996aeebc9a4c011f1262fc73 404 SUPERFAMILY SSF53686 7 392 1.83E-151 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HW35_02545 d20c0458996aeebc9a4c011f1262fc73 404 Gene3D G3DSA:3.40.50.1100 58 388 2.7E-194 T 12-10-2018 HW35_11545 a94370491b9595e136dce20cd09573d5 149 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 145 6.2E-45 T 12-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 HW35_11545 a94370491b9595e136dce20cd09573d5 149 Gene3D G3DSA:3.40.630.30 7 149 2.2E-44 T 12-10-2018 HW35_11545 a94370491b9595e136dce20cd09573d5 149 Pfam PF00583 Acetyltransferase (GNAT) family 16 125 4.2E-18 T 12-10-2018 IPR000182 GNAT domain HW35_11545 a94370491b9595e136dce20cd09573d5 149 SUPERFAMILY SSF55729 5 148 2.74E-35 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_12400 813340416e6c989b96b8b6fbbe6f6e33 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 268 9.0E-62 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_12400 813340416e6c989b96b8b6fbbe6f6e33 271 SMART SM00062 47 270 9.4E-84 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_12400 813340416e6c989b96b8b6fbbe6f6e33 271 SMART SM00079 45 269 5.3E-7 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HW35_12400 813340416e6c989b96b8b6fbbe6f6e33 271 SUPERFAMILY SSF53850 8 268 3.18E-72 T 12-10-2018 HW35_12400 813340416e6c989b96b8b6fbbe6f6e33 271 Gene3D G3DSA:3.40.190.10 135 232 2.2E-87 T 12-10-2018 HW35_12400 813340416e6c989b96b8b6fbbe6f6e33 271 Gene3D G3DSA:3.40.190.10 48 266 2.2E-87 T 12-10-2018 HW35_07845 bb4debeaeec3d5ac495057734bd3e823 288 PIRSF PIRSF006483 3 288 1.5E-93 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT HW35_07845 bb4debeaeec3d5ac495057734bd3e823 288 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 228 282 5.8E-20 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 HW35_07845 bb4debeaeec3d5ac495057734bd3e823 288 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 19 222 6.7E-71 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT HW35_07845 bb4debeaeec3d5ac495057734bd3e823 288 Gene3D G3DSA:3.30.70.120 201 275 3.6E-26 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HW35_15900 2f3544cd87bcdb62d9acf31ecca65788 374 SUPERFAMILY SSF53187 2 365 2.47E-66 T 12-10-2018 HW35_15900 2f3544cd87bcdb62d9acf31ecca65788 374 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 1 370 63.958 T 12-10-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 HW35_15900 2f3544cd87bcdb62d9acf31ecca65788 374 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 4 359 1.3E-85 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 HW35_15900 2f3544cd87bcdb62d9acf31ecca65788 374 SUPERFAMILY SSF55031 176 281 1.31E-28 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain HW35_15900 2f3544cd87bcdb62d9acf31ecca65788 374 PIRSF PIRSF005962 1 373 6.6E-106 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 HW35_15900 2f3544cd87bcdb62d9acf31ecca65788 374 Gene3D G3DSA:3.40.630.10 4 353 1.5E-117 T 12-10-2018 HW35_15900 2f3544cd87bcdb62d9acf31ecca65788 374 Gene3D G3DSA:3.30.70.360 171 285 1.5E-117 T 12-10-2018 HW35_15900 2f3544cd87bcdb62d9acf31ecca65788 374 Pfam PF07687 Peptidase dimerisation domain 178 267 6.9E-10 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain HW35_15900 2f3544cd87bcdb62d9acf31ecca65788 374 Pfam PF01546 Peptidase family M20/M25/M40 65 367 2.2E-25 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 HW35_16615 ceea519b1e4f9103924ccfe61579e9ed 220 Gene3D G3DSA:3.30.70.260 139 217 1.3E-15 T 12-10-2018 HW35_16615 ceea519b1e4f9103924ccfe61579e9ed 220 SUPERFAMILY SSF55021 137 217 1.94E-18 T 12-10-2018 HW35_16615 ceea519b1e4f9103924ccfe61579e9ed 220 Pfam PF01842 ACT domain 149 210 8.4E-12 T 12-10-2018 IPR002912 ACT domain HW35_16615 ceea519b1e4f9103924ccfe61579e9ed 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 1.2E-98 T 12-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 HW35_16615 ceea519b1e4f9103924ccfe61579e9ed 220 Pfam PF03315 Serine dehydratase beta chain 5 74 3.8E-11 T 12-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 HW35_16615 ceea519b1e4f9103924ccfe61579e9ed 220 PIRSF PIRSF036692 1 220 1.1E-105 T 12-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 HW35_16615 ceea519b1e4f9103924ccfe61579e9ed 220 Gene3D G3DSA:3.30.1330.90 13 87 1.2E-17 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 HW35_16615 ceea519b1e4f9103924ccfe61579e9ed 220 SUPERFAMILY SSF143548 19 137 1.44E-31 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 HW35_04015 f4bd9af5039e1999dd71c7a63d9940fc 206 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 3 111 1.7E-36 T 12-10-2018 IPR014245 Sporulation stage III, protein AF HW35_04015 f4bd9af5039e1999dd71c7a63d9940fc 206 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 199 1.8E-40 T 12-10-2018 IPR014245 Sporulation stage III, protein AF HW35_04315 7f3f46af22910691b2e03e92f1d73647 697 SUPERFAMILY SSF56601 313 684 1.39E-67 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_04315 7f3f46af22910691b2e03e92f1d73647 697 Pfam PF00905 Penicillin binding protein transpeptidase domain 346 678 1.3E-68 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HW35_04315 7f3f46af22910691b2e03e92f1d73647 697 Pfam PF03717 Penicillin-binding Protein dimerisation domain 59 298 1.0E-40 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HW35_04315 7f3f46af22910691b2e03e92f1d73647 697 Gene3D G3DSA:3.40.710.10 313 664 6.1E-234 T 12-10-2018 HW35_04315 7f3f46af22910691b2e03e92f1d73647 697 SUPERFAMILY SSF56519 56 313 3.4E-36 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 HW35_04315 7f3f46af22910691b2e03e92f1d73647 697 Gene3D G3DSA:1.10.10.1230 86 188 6.1E-234 T 12-10-2018 HW35_04315 7f3f46af22910691b2e03e92f1d73647 697 Gene3D G3DSA:3.90.1310.30 61 569 6.1E-234 T 12-10-2018 HW35_08825 3b08824c90ca4edfa84febc86a7536e2 297 SUPERFAMILY SSF53448 4 274 2.29E-67 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_08825 3b08824c90ca4edfa84febc86a7536e2 297 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 7.8E-120 T 12-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 HW35_08825 3b08824c90ca4edfa84febc86a7536e2 297 Gene3D G3DSA:3.90.550.10 1 290 5.9E-93 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_08825 3b08824c90ca4edfa84febc86a7536e2 297 Pfam PF00483 Nucleotidyl transferase 6 258 6.3E-33 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HW35_05005 894af926d78fe9c30b8a11631595a005 525 SUPERFAMILY SSF51905 2 388 5.43E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_05005 894af926d78fe9c30b8a11631595a005 525 Pfam PF00890 FAD binding domain 5 372 3.7E-77 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05005 894af926d78fe9c30b8a11631595a005 525 Gene3D G3DSA:3.90.700.10 232 327 2.6E-123 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05005 894af926d78fe9c30b8a11631595a005 525 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 335 357 1.4E-6 T 12-10-2018 HW35_05005 894af926d78fe9c30b8a11631595a005 525 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.4E-6 T 12-10-2018 HW35_05005 894af926d78fe9c30b8a11631595a005 525 SUPERFAMILY SSF56425 222 332 1.33E-31 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05005 894af926d78fe9c30b8a11631595a005 525 Pfam PF02910 Fumarate reductase flavoprotein C-term 415 522 2.6E-16 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_05005 894af926d78fe9c30b8a11631595a005 525 Gene3D G3DSA:3.50.50.60 5 381 2.6E-123 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_05005 894af926d78fe9c30b8a11631595a005 525 Gene3D G3DSA:1.20.58.100 408 514 7.2E-20 T 12-10-2018 HW35_05005 894af926d78fe9c30b8a11631595a005 525 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 492 1.8E-157 T 12-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 HW35_05005 894af926d78fe9c30b8a11631595a005 525 SUPERFAMILY SSF46977 415 521 1.31E-23 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HW35_14990 2e66723ce897dc82512510ef22abbb27 717 Gene3D G3DSA:1.10.287.950 378 518 3.1E-5 T 12-10-2018 HW35_14990 2e66723ce897dc82512510ef22abbb27 717 Pfam PF12698 ABC-2 family transporter protein 372 700 7.7E-17 T 12-10-2018 HW35_14990 2e66723ce897dc82512510ef22abbb27 717 Pfam PF12698 ABC-2 family transporter protein 24 170 2.1E-12 T 12-10-2018 HW35_14990 2e66723ce897dc82512510ef22abbb27 717 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 504 706 5.6E-67 T 12-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal HW35_14990 2e66723ce897dc82512510ef22abbb27 717 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 9 171 3.3E-63 T 12-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal HW35_14990 2e66723ce897dc82512510ef22abbb27 717 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 459 484 1.4E-5 T 12-10-2018 IPR023908 xxxLxxG heptad repeat HW35_14990 2e66723ce897dc82512510ef22abbb27 717 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 438 464 4.1E-6 T 12-10-2018 IPR023908 xxxLxxG heptad repeat HW35_14990 2e66723ce897dc82512510ef22abbb27 717 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 175 201 1.5E-4 T 12-10-2018 IPR023908 xxxLxxG heptad repeat HW35_14990 2e66723ce897dc82512510ef22abbb27 717 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 417 443 4.5E-6 T 12-10-2018 IPR023908 xxxLxxG heptad repeat HW35_14990 2e66723ce897dc82512510ef22abbb27 717 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 189 214 1.6E-4 T 12-10-2018 IPR023908 xxxLxxG heptad repeat HW35_14990 2e66723ce897dc82512510ef22abbb27 717 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 445 471 2.1E-6 T 12-10-2018 IPR023908 xxxLxxG heptad repeat HW35_01380 4c800b01b89c2f31e68b1058b7ead5c5 157 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 31 152 4.7E-36 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 HW35_01380 4c800b01b89c2f31e68b1058b7ead5c5 157 PIRSF PIRSF006113 26 152 3.5E-26 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 HW35_01380 4c800b01b89c2f31e68b1058b7ead5c5 157 Gene3D G3DSA:3.30.479.10 26 101 1.4E-24 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 HW35_01380 4c800b01b89c2f31e68b1058b7ead5c5 157 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 31 120 5.7E-31 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 HW35_01380 4c800b01b89c2f31e68b1058b7ead5c5 157 Gene3D G3DSA:3.30.479.10 102 156 6.9E-11 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 HW35_01380 4c800b01b89c2f31e68b1058b7ead5c5 157 SUPERFAMILY SSF55620 25 152 8.34E-38 T 12-10-2018 HW35_05620 52c28824894cdfb7d797aa1c104f6a48 209 Pfam PF02659 Putative manganese efflux pump 125 206 8.2E-9 T 12-10-2018 IPR003810 Putative manganese efflux pump HW35_05620 52c28824894cdfb7d797aa1c104f6a48 209 Pfam PF02659 Putative manganese efflux pump 4 83 3.6E-10 T 12-10-2018 IPR003810 Putative manganese efflux pump HW35_05620 52c28824894cdfb7d797aa1c104f6a48 209 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 6 209 2.2E-72 T 12-10-2018 IPR014205 Sporulation protein YtaF HW35_03070 48701a665fce9ef7710c7c96daab8f32 643 SUPERFAMILY SSF52540 51 620 5.07E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03070 48701a665fce9ef7710c7c96daab8f32 643 SMART SM00491 499 623 2.3E-10 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 HW35_03070 48701a665fce9ef7710c7c96daab8f32 643 Gene3D G3DSA:3.40.50.300 36 314 6.0E-29 T 12-10-2018 HW35_03070 48701a665fce9ef7710c7c96daab8f32 643 Pfam PF13307 Helicase C-terminal domain 485 628 2.7E-24 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 HW35_03070 48701a665fce9ef7710c7c96daab8f32 643 Gene3D G3DSA:3.40.50.300 458 636 1.3E-25 T 12-10-2018 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 307 8.7E-30 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 Hamap MF_01685 Ferredoxin--NADP reductase. 6 333 37.685 T 12-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 8.7E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 298 8.7E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 8.7E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 202 218 8.7E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 8.7E-25 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.4E-18 T 12-10-2018 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.4E-18 T 12-10-2018 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 1.4E-18 T 12-10-2018 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 1.4E-18 T 12-10-2018 HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 Gene3D G3DSA:3.50.50.60 7 309 8.9E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 Gene3D G3DSA:3.50.50.60 127 248 8.9E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_12240 b8db06b5b7bd907570b85da1b4298cd1 349 SUPERFAMILY SSF51905 1 318 2.81E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_16175 f32237856753c5499492ef4a40e6abc9 105 Pfam PF13518 Helix-turn-helix domain 21 68 4.8E-8 T 12-10-2018 HW35_16175 f32237856753c5499492ef4a40e6abc9 105 SUPERFAMILY SSF46689 13 95 8.42E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_09725 670c4d97581c3b4e06c431327714829c 131 Gene3D G3DSA:3.10.129.10 1 130 1.2E-15 T 12-10-2018 HW35_09725 670c4d97581c3b4e06c431327714829c 131 SUPERFAMILY SSF54637 8 123 4.7E-11 T 12-10-2018 IPR029069 HotDog domain superfamily HW35_09725 670c4d97581c3b4e06c431327714829c 131 Pfam PF13452 N-terminal half of MaoC dehydratase 4 116 1.3E-6 T 12-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 HW35_04480 c1bedbba6d2f301583e6dfec65c5376a 158 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 153 6.3E-42 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HW35_04480 c1bedbba6d2f301583e6dfec65c5376a 158 Pfam PF02130 Uncharacterized protein family UPF0054 21 151 1.1E-47 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HW35_04480 c1bedbba6d2f301583e6dfec65c5376a 158 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 156 24.527 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HW35_04480 c1bedbba6d2f301583e6dfec65c5376a 158 SUPERFAMILY SSF55486 3 156 2.03E-45 T 12-10-2018 HW35_04480 c1bedbba6d2f301583e6dfec65c5376a 158 Gene3D G3DSA:3.40.390.30 2 158 9.3E-47 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 HW35_04480 c1bedbba6d2f301583e6dfec65c5376a 158 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 122 132 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site HW35_00955 7c251941217609f662b5cd43ef0a51e0 51 ProDom PD050103 O SPORE SMALL ACID-SOLUBLE SASP SPORULATION CAPSID COAT K SEQUENCING 3 47 4.0E-12 T 12-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 HW35_00955 7c251941217609f662b5cd43ef0a51e0 51 Pfam PF08175 Small acid-soluble spore protein O family 2 47 6.7E-20 T 12-10-2018 HW35_00955 7c251941217609f662b5cd43ef0a51e0 51 TIGRFAM TIGR02864 spore_sspO: small, acid-soluble spore protein O 1 47 1.1E-21 T 12-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 HW35_14255 f89aeff50f2433ecf39a5f1c4b8014b0 70 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 4 63 7.2E-13 T 12-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 HW35_14255 f89aeff50f2433ecf39a5f1c4b8014b0 70 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 14 66 5.4E-16 T 12-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 SUPERFAMILY SSF53671 8 315 5.5E-115 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 11 314 9.6E-137 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 Gene3D G3DSA:3.40.50.1370 141 310 5.3E-131 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 312 7.8E-62 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 2.8E-29 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 279 302 2.8E-29 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 2.8E-29 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 2.8E-29 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 Gene3D G3DSA:3.40.50.1370 11 140 5.3E-131 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 10 315 84.379 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 87 100 1.9E-31 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 54 68 1.9E-31 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 231 241 1.9E-31 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 127 141 1.9E-31 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 293 304 1.9E-31 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HW35_14155 73d3906f3e706bcccce72aa6af909eb7 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 151 1.7E-56 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 HW35_01590 341c75a0f0c955c811e2b25090f1c8c2 342 Pfam PF11553 Protein of unknown function (DUF3231) 182 342 3.6E-40 T 12-10-2018 IPR021617 Protein of unknown function DUF3231 HW35_01590 341c75a0f0c955c811e2b25090f1c8c2 342 Pfam PF11553 Protein of unknown function (DUF3231) 14 170 6.8E-41 T 12-10-2018 IPR021617 Protein of unknown function DUF3231 HW35_01590 341c75a0f0c955c811e2b25090f1c8c2 342 Gene3D G3DSA:1.20.1260.10 12 151 1.1E-8 T 12-10-2018 IPR012347 Ferritin-like HW35_01590 341c75a0f0c955c811e2b25090f1c8c2 342 Gene3D G3DSA:1.20.1260.10 186 329 5.0E-10 T 12-10-2018 IPR012347 Ferritin-like HW35_05355 9fdad40791c6ccc6540a78dfb995d1f6 252 Hamap MF_00564 Ribonuclease PH [rph]. 11 238 44.101 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 HW35_05355 9fdad40791c6ccc6540a78dfb995d1f6 252 Gene3D G3DSA:3.30.230.70 1 244 4.9E-62 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_05355 9fdad40791c6ccc6540a78dfb995d1f6 252 SUPERFAMILY SSF55666 153 238 7.46E-24 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_05355 9fdad40791c6ccc6540a78dfb995d1f6 252 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 2.8E-23 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_05355 9fdad40791c6ccc6540a78dfb995d1f6 252 Pfam PF03725 3' exoribonuclease family, domain 2 159 224 1.5E-8 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HW35_05355 9fdad40791c6ccc6540a78dfb995d1f6 252 SUPERFAMILY SSF54211 1 182 1.27E-46 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HW35_05355 9fdad40791c6ccc6540a78dfb995d1f6 252 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 12-10-2018 IPR018336 Ribonuclease PH, conserved site HW35_05355 9fdad40791c6ccc6540a78dfb995d1f6 252 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 237 7.0E-116 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 HW35_08385 cb9fa21e664d2cdf46b86c34955f354f 426 Pfam PF07690 Major Facilitator Superfamily 18 374 9.2E-54 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_08385 cb9fa21e664d2cdf46b86c34955f354f 426 Gene3D G3DSA:1.20.1250.20 1 203 3.4E-39 T 12-10-2018 HW35_08385 cb9fa21e664d2cdf46b86c34955f354f 426 SUPERFAMILY SSF103473 6 411 9.29E-80 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_08385 cb9fa21e664d2cdf46b86c34955f354f 426 Gene3D G3DSA:1.20.1250.20 221 412 5.1E-32 T 12-10-2018 HW35_04935 6c7dc73f7694ad71bda2d5d8d4fcbfcb 223 Pfam PF04239 Protein of unknown function (DUF421) 89 200 2.2E-36 T 12-10-2018 IPR007353 Protein of unknown function DUF421 HW35_04935 6c7dc73f7694ad71bda2d5d8d4fcbfcb 223 Gene3D G3DSA:3.30.240.20 81 154 1.7E-25 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily HW35_04935 6c7dc73f7694ad71bda2d5d8d4fcbfcb 223 Gene3D G3DSA:3.30.240.20 165 223 1.5E-17 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily HW35_01875 949cc06b3ebcd67e88c663614ce238c1 726 Gene3D G3DSA:1.20.1220.12 582 725 2.6E-73 T 12-10-2018 HW35_01875 949cc06b3ebcd67e88c663614ce238c1 726 Hamap MF_00641 Malate synthase G [glcB]. 1 726 392.095 T 12-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 HW35_01875 949cc06b3ebcd67e88c663614ce238c1 726 Gene3D G3DSA:2.170.170.11 134 263 3.9E-277 T 12-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 HW35_01875 949cc06b3ebcd67e88c663614ce238c1 726 SUPERFAMILY SSF51645 2 721 4.71E-304 T 12-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 HW35_01875 949cc06b3ebcd67e88c663614ce238c1 726 Pfam PF01274 Malate synthase 17 696 7.4E-171 T 12-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 HW35_01875 949cc06b3ebcd67e88c663614ce238c1 726 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 721 0.0 T 12-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 HW35_01875 949cc06b3ebcd67e88c663614ce238c1 726 Gene3D G3DSA:3.20.20.360 7 579 3.9E-277 T 12-10-2018 HW35_07735 cf22d15e4873b1ecf7c1ed691fe124b7 689 SUPERFAMILY SSF51445 130 520 1.79E-105 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily HW35_07735 cf22d15e4873b1ecf7c1ed691fe124b7 689 SUPERFAMILY SSF49373 71 105 2.24E-5 T 12-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments HW35_07735 cf22d15e4873b1ecf7c1ed691fe124b7 689 Gene3D G3DSA:3.40.50.1700 506 689 9.6E-37 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 HW35_07735 cf22d15e4873b1ecf7c1ed691fe124b7 689 SUPERFAMILY SSF52279 521 689 8.37E-14 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 HW35_07735 cf22d15e4873b1ecf7c1ed691fe124b7 689 Gene3D G3DSA:2.60.40.1080 28 119 6.6E-7 T 12-10-2018 HW35_07735 cf22d15e4873b1ecf7c1ed691fe124b7 689 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 144 478 3.3E-109 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HW35_07735 cf22d15e4873b1ecf7c1ed691fe124b7 689 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 521 689 1.6E-9 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 HW35_07735 cf22d15e4873b1ecf7c1ed691fe124b7 689 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 399 416 - T 12-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 HW35_07735 cf22d15e4873b1ecf7c1ed691fe124b7 689 Gene3D G3DSA:3.20.20.300 132 505 1.6E-148 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 HW35_02740 50ad73864ae51cc3839534e4fb862ca0 230 Gene3D G3DSA:3.40.1080.10 6 222 2.5E-69 T 12-10-2018 HW35_02740 50ad73864ae51cc3839534e4fb862ca0 230 SMART SM00882 8 220 6.9E-64 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 HW35_02740 50ad73864ae51cc3839534e4fb862ca0 230 SUPERFAMILY SSF100950 6 222 4.47E-70 T 12-10-2018 IPR037171 NagB/RpiA transferase-like HW35_02740 50ad73864ae51cc3839534e4fb862ca0 230 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 8 220 1.0E-61 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 HW35_02740 50ad73864ae51cc3839534e4fb862ca0 230 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 20 35 - T 12-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 HW35_02740 50ad73864ae51cc3839534e4fb862ca0 230 Pfam PF01144 Coenzyme A transferase 10 218 1.4E-62 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 Gene3D G3DSA:3.30.1370.70 1 90 3.8E-28 T 12-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 Pfam PF13769 Virulence factor 109 189 6.0E-27 T 12-10-2018 IPR025989 Virulence factor domain HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 Gene3D G3DSA:1.25.10.10 189 377 4.6E-27 T 12-10-2018 IPR011989 Armadillo-like helical HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 SMART SM00932 4 90 5.6E-29 T 12-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 4 85 2.9E-19 T 12-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 SUPERFAMILY SSF48371 213 373 4.22E-33 T 12-10-2018 IPR016024 Armadillo-type fold HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 SMART SM00567 E-Z type HEAT repeats 281 310 0.049 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 SMART SM00567 E-Z type HEAT repeats 250 279 5.6E-4 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 SMART SM00567 E-Z type HEAT repeats 312 341 5.4E-4 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 SUPERFAMILY SSF110836 2 86 3.66E-23 T 12-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily HW35_02900 c8ad9e8f635b8e47d6b0dd0ce778398b 378 Pfam PF13646 HEAT repeats 270 344 1.2E-12 T 12-10-2018 HW35_12300 c6b673615021100dede80a655d5a9bc0 152 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 7 129 5.5E-33 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 HW35_12300 c6b673615021100dede80a655d5a9bc0 152 Gene3D G3DSA:3.10.450.50 1 152 2.9E-37 T 12-10-2018 HW35_12300 c6b673615021100dede80a655d5a9bc0 152 Pfam PF13474 SnoaL-like domain 9 121 1.1E-9 T 12-10-2018 IPR037401 SnoaL-like domain HW35_12300 c6b673615021100dede80a655d5a9bc0 152 SUPERFAMILY SSF54427 5 146 8.96E-33 T 12-10-2018 IPR032710 NTF2-like domain superfamily HW35_08610 2a5f6c5e7479be9373788ebf4108d19b 241 Gene3D G3DSA:3.40.50.10420 47 238 9.3E-34 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily HW35_08610 2a5f6c5e7479be9373788ebf4108d19b 241 SUPERFAMILY SSF100950 48 238 3.43E-36 T 12-10-2018 IPR037171 NagB/RpiA transferase-like HW35_08610 2a5f6c5e7479be9373788ebf4108d19b 241 Hamap MF_02104 Lactate utilization protein C [lutC]. 6 238 45.379 T 12-10-2018 IPR022823 Lactate utilization protein C HW35_08610 2a5f6c5e7479be9373788ebf4108d19b 241 Pfam PF02589 LUD domain 59 238 4.9E-28 T 12-10-2018 IPR003741 LUD domain HW35_04660 24e337b38eebc9103addf34632c7ab46 171 Gene3D G3DSA:3.40.50.1000 16 151 1.6E-21 T 12-10-2018 IPR023214 HAD superfamily HW35_04660 24e337b38eebc9103addf34632c7ab46 171 SUPERFAMILY SSF56784 4 150 9.05E-25 T 12-10-2018 IPR036412 HAD-like superfamily HW35_04660 24e337b38eebc9103addf34632c7ab46 171 Pfam PF13419 Haloacid dehalogenase-like hydrolase 27 136 1.7E-9 T 12-10-2018 HW35_04660 24e337b38eebc9103addf34632c7ab46 171 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 28 138 5.0E-22 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 HW35_04660 24e337b38eebc9103addf34632c7ab46 171 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 4 164 8.4E-57 T 12-10-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like HW35_04370 b03c9a5c49341d33c1052ec1d8bbc124 85 ProDom PD060869 YQFT IG BH1387 1 68 9.0E-12 T 12-10-2018 IPR020277 Protein of unknown function DUF2624 HW35_04370 b03c9a5c49341d33c1052ec1d8bbc124 85 Pfam PF11116 Protein of unknown function (DUF2624) 3 82 2.6E-30 T 12-10-2018 IPR020277 Protein of unknown function DUF2624 HW35_13750 139e34b2052794cf47cea4604499d18c 270 Pfam PF14167 YfkD-like protein 39 270 9.2E-123 T 12-10-2018 IPR025548 YfkD-like protein HW35_05035 c524b60de34643e51735c5ac667328b0 179 SMART SM01317 59 172 2.7E-20 T 12-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal HW35_05035 c524b60de34643e51735c5ac667328b0 179 Gene3D G3DSA:3.30.565.30 58 174 3.1E-30 T 12-10-2018 IPR037100 Sporulation initiation phosphotransferase B, C-terminal domain superfamily HW35_05035 c524b60de34643e51735c5ac667328b0 179 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 60 170 4.2E-28 T 12-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal HW35_05035 c524b60de34643e51735c5ac667328b0 179 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 4 57 2.0E-21 T 12-10-2018 IPR039506 SpoOB, alpha-helical domain HW35_05035 c524b60de34643e51735c5ac667328b0 179 SUPERFAMILY SSF55890 1 171 3.27E-42 T 12-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 HW35_05035 c524b60de34643e51735c5ac667328b0 179 Gene3D G3DSA:1.10.287.130 1 57 9.4E-23 T 12-10-2018 HW35_00270 6cdec1cc260c66928d9f9c24de1763fd 295 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 215 287 1.8E-17 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HW35_00270 6cdec1cc260c66928d9f9c24de1763fd 295 SUPERFAMILY SSF117143 126 252 3.92E-21 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like HW35_00270 6cdec1cc260c66928d9f9c24de1763fd 295 Pfam PF00460 Flagella basal body rod protein 5 35 5.5E-7 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HW35_00270 6cdec1cc260c66928d9f9c24de1763fd 295 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 163 1.3E-26 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G HW35_11810 f178f952675af02196370993149fb210 150 Gene3D G3DSA:3.30.300.20 7 145 5.9E-31 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta HW35_11810 f178f952675af02196370993149fb210 150 Pfam PF02566 OsmC-like protein 39 141 2.4E-18 T 12-10-2018 IPR003718 OsmC/Ohr family HW35_11810 f178f952675af02196370993149fb210 150 SUPERFAMILY SSF82784 2 144 1.57E-31 T 12-10-2018 IPR036102 OsmC/Ohr superfamily HW35_11810 f178f952675af02196370993149fb210 150 TIGRFAM TIGR03563 perox_SACOL1771: peroxiredoxin, SACOL1771 subfamily 4 141 2.5E-66 T 12-10-2018 IPR019905 Peroxiredoxin OsmC-like protein, Firmicutes HW35_04950 b4699a54cadb874fab27a6899a2a3a4b 379 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 373 4.1E-187 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HW35_04950 b4699a54cadb874fab27a6899a2a3a4b 379 Gene3D G3DSA:3.20.20.105 2 373 7.9E-171 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HW35_04950 b4699a54cadb874fab27a6899a2a3a4b 379 SUPERFAMILY SSF51713 3 369 5.62E-162 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HW35_04950 b4699a54cadb874fab27a6899a2a3a4b 379 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 57.745 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HW35_04950 b4699a54cadb874fab27a6899a2a3a4b 379 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 373 2.5E-176 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HW35_04950 b4699a54cadb874fab27a6899a2a3a4b 379 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 8.9E-92 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HW35_09535 78cbb52a6d9468ade55620a1970e042a 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 288 4.4E-43 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 HW35_01130 ee70fad8a8543953703fd28711ce36b6 413 PIRSF PIRSF000151 1 413 8.7E-174 T 12-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 HW35_01130 ee70fad8a8543953703fd28711ce36b6 413 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 319 341 - T 12-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HW35_01130 ee70fad8a8543953703fd28711ce36b6 413 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 13 402 2.2E-161 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HW35_01130 ee70fad8a8543953703fd28711ce36b6 413 SUPERFAMILY SSF53720 4 412 4.71E-109 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HW35_01130 ee70fad8a8543953703fd28711ce36b6 413 Pfam PF00171 Aldehyde dehydrogenase family 5 291 9.4E-13 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 HW35_01130 ee70fad8a8543953703fd28711ce36b6 413 Gene3D G3DSA:3.40.605.10 16 407 4.5E-159 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_01130 ee70fad8a8543953703fd28711ce36b6 413 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 412 41.076 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HW35_01130 ee70fad8a8543953703fd28711ce36b6 413 Gene3D G3DSA:3.40.309.10 224 370 4.5E-159 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 HW35_01955 ee25f128804933ed32cc933fe4d9f9cb 198 SUPERFAMILY SSF81452 17 196 3.66E-50 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01955 ee25f128804933ed32cc933fe4d9f9cb 198 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 10 198 7.5E-74 T 12-10-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 HW35_01955 ee25f128804933ed32cc933fe4d9f9cb 198 Gene3D G3DSA:1.20.120.80 13 198 8.2E-50 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_01955 ee25f128804933ed32cc933fe4d9f9cb 198 Pfam PF00510 Cytochrome c oxidase subunit III 21 196 1.6E-17 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16760 997b8794eb3eab010f725371d3c318c7 259 Gene3D G3DSA:3.30.450.40 1 159 1.7E-70 T 12-10-2018 IPR029016 GAF-like domain superfamily HW35_16760 997b8794eb3eab010f725371d3c318c7 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 152.177 T 12-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 HW35_16760 997b8794eb3eab010f725371d3c318c7 259 Gene3D G3DSA:1.10.10.10 160 259 1.1E-47 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_16760 997b8794eb3eab010f725371d3c318c7 259 SUPERFAMILY SSF46785 167 256 1.45E-42 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_16760 997b8794eb3eab010f725371d3c318c7 259 Pfam PF08222 CodY helix-turn-helix domain 198 257 7.6E-38 T 12-10-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal HW35_16760 997b8794eb3eab010f725371d3c318c7 259 PIRSF PIRSF011572 1 257 4.6E-125 T 12-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 HW35_16760 997b8794eb3eab010f725371d3c318c7 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 2.2E-127 T 12-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 HW35_16760 997b8794eb3eab010f725371d3c318c7 259 Pfam PF06018 CodY GAF-like domain 3 178 3.9E-82 T 12-10-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 HW35_14205 612d6f3ecebafd0220beef7044657e3e 494 Gene3D G3DSA:1.20.1730.10 21 492 6.1E-36 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily HW35_14205 612d6f3ecebafd0220beef7044657e3e 494 Pfam PF00474 Sodium:solute symporter family 35 428 5.9E-22 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 HW35_06330 b8a6c608210012cbe2e718e0e64acda5 157 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HW35_06330 b8a6c608210012cbe2e718e0e64acda5 157 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 154 8.1E-54 T 12-10-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 HW35_06330 b8a6c608210012cbe2e718e0e64acda5 157 SUPERFAMILY SSF55811 28 119 2.71E-19 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 HW35_06330 b8a6c608210012cbe2e718e0e64acda5 157 Gene3D G3DSA:3.90.79.10 1 156 3.8E-38 T 12-10-2018 HW35_06330 b8a6c608210012cbe2e718e0e64acda5 157 Pfam PF00293 NUDIX domain 36 115 6.4E-13 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HW35_06330 b8a6c608210012cbe2e718e0e64acda5 157 PRINTS PR00502 NUDIX hydrolase family signature 48 62 6.3E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HW35_06330 b8a6c608210012cbe2e718e0e64acda5 157 PRINTS PR00502 NUDIX hydrolase family signature 62 77 6.3E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HW35_08720 443e7de6c1aa92da7241017075a26a67 292 Gene3D G3DSA:3.30.420.40 1 102 6.9E-32 T 12-10-2018 HW35_08720 443e7de6c1aa92da7241017075a26a67 292 Gene3D G3DSA:3.30.420.40 103 292 3.0E-72 T 12-10-2018 HW35_08720 443e7de6c1aa92da7241017075a26a67 292 ProSitePatterns PS01125 ROK family signature. 128 153 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 HW35_08720 443e7de6c1aa92da7241017075a26a67 292 Pfam PF00480 ROK family 3 282 1.0E-74 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 HW35_08720 443e7de6c1aa92da7241017075a26a67 292 SUPERFAMILY SSF53067 3 285 5.71E-50 T 12-10-2018 HW35_01505 85dd99847937ad3b197b68db958df661 143 Gene3D G3DSA:3.40.1350.10 51 134 3.2E-6 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 HW35_10370 ca9fa0a2ec89a1f435ff17c5dff02f3b 292 Gene3D G3DSA:3.90.1280.10 234 292 1.4E-23 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 HW35_10370 ca9fa0a2ec89a1f435ff17c5dff02f3b 292 Gene3D G3DSA:3.55.30.10 2 233 1.5E-95 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 HW35_10370 ca9fa0a2ec89a1f435ff17c5dff02f3b 292 SUPERFAMILY SSF118352 231 290 7.32E-21 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 HW35_10370 ca9fa0a2ec89a1f435ff17c5dff02f3b 292 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 42.463 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HW35_10370 ca9fa0a2ec89a1f435ff17c5dff02f3b 292 PIRSF PIRSF005261 1 292 1.2E-79 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HW35_10370 ca9fa0a2ec89a1f435ff17c5dff02f3b 292 SUPERFAMILY SSF64397 2 241 8.37E-79 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 HW35_10370 ca9fa0a2ec89a1f435ff17c5dff02f3b 292 Pfam PF01430 Hsp33 protein 3 280 4.4E-91 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HW35_02620 3ecd975dfcd4faee0fb7154bd8be40bb 179 SUPERFAMILY SSF46785 3 175 3.09E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_02620 3ecd975dfcd4faee0fb7154bd8be40bb 179 Gene3D G3DSA:1.10.10.10 1 97 1.2E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_02620 3ecd975dfcd4faee0fb7154bd8be40bb 179 Pfam PF03551 Transcriptional regulator PadR-like family 6 82 1.3E-9 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal HW35_10265 0bda33b063e44f352cb32283283676c9 318 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 6.6E-52 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HW35_10265 0bda33b063e44f352cb32283283676c9 318 Gene3D G3DSA:3.40.50.2020 13 306 3.1E-126 T 12-10-2018 HW35_10265 0bda33b063e44f352cb32283283676c9 318 SMART SM01400 10 126 6.4E-83 T 12-10-2018 HW35_10265 0bda33b063e44f352cb32283283676c9 318 Gene3D G3DSA:3.40.50.2020 153 294 3.1E-126 T 12-10-2018 HW35_10265 0bda33b063e44f352cb32283283676c9 318 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 10 318 51.947 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 HW35_10265 0bda33b063e44f352cb32283283676c9 318 SUPERFAMILY SSF53271 75 309 1.86E-66 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like HW35_10265 0bda33b063e44f352cb32283283676c9 318 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 HW35_10265 0bda33b063e44f352cb32283283676c9 318 Pfam PF14572 Phosphoribosyl synthetase-associated domain 209 317 1.1E-26 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HW35_10265 0bda33b063e44f352cb32283283676c9 318 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 318 1.1E-129 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HW35_07075 a0c9ec577899ef99ed4ebcf75bf86901 261 SUPERFAMILY SSF52540 5 233 6.3E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07075 a0c9ec577899ef99ed4ebcf75bf86901 261 Pfam PF00005 ABC transporter 21 173 2.9E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_07075 a0c9ec577899ef99ed4ebcf75bf86901 261 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 246 5.9E-113 T 12-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 HW35_07075 a0c9ec577899ef99ed4ebcf75bf86901 261 SMART SM00382 30 225 2.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_07075 a0c9ec577899ef99ed4ebcf75bf86901 261 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_07075 a0c9ec577899ef99ed4ebcf75bf86901 261 Gene3D G3DSA:3.40.50.300 4 253 1.4E-55 T 12-10-2018 HW35_13535 44594dfe7b91a31db88653cd491ceb6c 443 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 10 413 5.6E-128 T 12-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 HW35_13535 44594dfe7b91a31db88653cd491ceb6c 443 Pfam PF05525 Branched-chain amino acid transport protein 3 426 7.5E-147 T 12-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 HW35_13865 7bb61898bb9d32cefacef64e712edd64 373 PIRSF PIRSF006078 1 371 2.6E-121 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 HW35_13865 7bb61898bb9d32cefacef64e712edd64 373 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 367 1.3E-128 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 HW35_13865 7bb61898bb9d32cefacef64e712edd64 373 Gene3D G3DSA:3.90.1510.10 42 271 9.3E-132 T 12-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 HW35_13865 7bb61898bb9d32cefacef64e712edd64 373 Pfam PF02595 Glycerate kinase family 3 367 6.7E-134 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 HW35_13865 7bb61898bb9d32cefacef64e712edd64 373 SUPERFAMILY SSF110738 1 367 1.22E-121 T 12-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 HW35_13865 7bb61898bb9d32cefacef64e712edd64 373 Gene3D G3DSA:3.40.50.10350 1 356 9.3E-132 T 12-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold HW35_05465 96e23e4e4513af58431d1b4492916897 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 253 5.3E-71 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 HW35_05465 96e23e4e4513af58431d1b4492916897 254 SUPERFAMILY SSF52096 4 254 6.47E-87 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_05465 96e23e4e4513af58431d1b4492916897 254 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 95 115 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 HW35_05465 96e23e4e4513af58431d1b4492916897 254 Gene3D G3DSA:3.90.226.10 1 254 6.2E-94 T 12-10-2018 HW35_04810 cb3682b6904e44addb836c191d5ebd86 372 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 10 358 3.7E-142 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 HW35_04810 cb3682b6904e44addb836c191d5ebd86 372 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 9 359 41.384 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 HW35_04810 cb3682b6904e44addb836c191d5ebd86 372 Gene3D G3DSA:2.30.30.280 215 279 5.5E-23 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 HW35_04810 cb3682b6904e44addb836c191d5ebd86 372 Gene3D G3DSA:3.40.50.620 1 214 2.3E-99 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_04810 cb3682b6904e44addb836c191d5ebd86 372 Gene3D G3DSA:2.40.30.10 280 371 4.9E-31 T 12-10-2018 HW35_04810 cb3682b6904e44addb836c191d5ebd86 372 Pfam PF03054 tRNA methyl transferase 10 358 3.2E-149 T 12-10-2018 HW35_04810 cb3682b6904e44addb836c191d5ebd86 372 SUPERFAMILY SSF52402 10 245 5.73E-58 T 12-10-2018 HW35_05730 2cb074f41c6b1f0c6088adc2d104b0ad 310 SUPERFAMILY SSF64182 12 303 7.06E-75 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily HW35_05730 2cb074f41c6b1f0c6088adc2d104b0ad 310 Pfam PF01368 DHH family 15 153 2.1E-12 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HW35_05730 2cb074f41c6b1f0c6088adc2d104b0ad 310 Pfam PF02272 DHHA1 domain 178 308 1.0E-13 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HW35_05730 2cb074f41c6b1f0c6088adc2d104b0ad 310 Gene3D G3DSA:3.10.310.30 199 310 4.1E-37 T 12-10-2018 HW35_05730 2cb074f41c6b1f0c6088adc2d104b0ad 310 Gene3D G3DSA:3.90.1640.10 1 196 3.9E-58 T 12-10-2018 HW35_03285 fbe5d1309e3b77a8bc07d1f0f6f3d058 224 Gene3D G3DSA:1.20.810.10 1 224 2.1E-86 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 HW35_03285 fbe5d1309e3b77a8bc07d1f0f6f3d058 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 5.8E-48 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 HW35_03285 fbe5d1309e3b77a8bc07d1f0f6f3d058 224 SUPERFAMILY SSF81342 6 224 7.53E-60 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 HW35_03285 fbe5d1309e3b77a8bc07d1f0f6f3d058 224 PIRSF PIRSF000032 2 224 3.7E-101 T 12-10-2018 HW35_02530 bc0aa39e056729725a9fc783a1ac22c2 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_02530 bc0aa39e056729725a9fc783a1ac22c2 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 529 1.7E-18 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_02530 bc0aa39e056729725a9fc783a1ac22c2 548 Gene3D G3DSA:3.30.300.310 441 545 7.1E-34 T 12-10-2018 HW35_02530 bc0aa39e056729725a9fc783a1ac22c2 548 SUPERFAMILY SSF56801 6 541 1.31E-157 T 12-10-2018 HW35_02530 bc0aa39e056729725a9fc783a1ac22c2 548 Gene3D G3DSA:3.40.50.12780 2 435 1.8E-122 T 12-10-2018 HW35_02530 bc0aa39e056729725a9fc783a1ac22c2 548 Pfam PF00501 AMP-binding enzyme 13 445 7.0E-111 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_13525 a6c1d232eb2a76986fa9eb5a8c6e0bd9 145 SUPERFAMILY SSF55729 1 138 3.95E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_13525 a6c1d232eb2a76986fa9eb5a8c6e0bd9 145 Pfam PF13673 Acetyltransferase (GNAT) domain 31 136 2.1E-18 T 12-10-2018 IPR000182 GNAT domain HW35_13525 a6c1d232eb2a76986fa9eb5a8c6e0bd9 145 Gene3D G3DSA:3.40.630.30 6 135 3.6E-27 T 12-10-2018 HW35_06825 f925529f1d78a95732f44715543f7530 133 PRINTS PR00681 Ribosomal protein S1 signature 60 78 8.8E-11 T 12-10-2018 HW35_06825 f925529f1d78a95732f44715543f7530 133 PRINTS PR00681 Ribosomal protein S1 signature 21 40 8.8E-11 T 12-10-2018 HW35_06825 f925529f1d78a95732f44715543f7530 133 SUPERFAMILY SSF50249 5 88 1.5E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_06825 f925529f1d78a95732f44715543f7530 133 SMART SM00316 6 77 2.7E-26 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_06825 f925529f1d78a95732f44715543f7530 133 Pfam PF00575 S1 RNA binding domain 4 77 1.5E-21 T 12-10-2018 IPR003029 S1 domain GO:0003676 HW35_06825 f925529f1d78a95732f44715543f7530 133 Gene3D G3DSA:2.40.50.140 2 87 3.0E-32 T 12-10-2018 HW35_12075 616152d2e8167bfbe72e346911cd4f07 352 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 175 184 - T 12-10-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 HW35_12075 616152d2e8167bfbe72e346911cd4f07 352 Gene3D G3DSA:2.70.98.10 9 349 6.2E-118 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 HW35_12075 616152d2e8167bfbe72e346911cd4f07 352 SUPERFAMILY SSF74650 6 345 1.44E-108 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 HW35_12075 616152d2e8167bfbe72e346911cd4f07 352 Pfam PF01263 Aldose 1-epimerase 18 344 1.8E-87 T 12-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 HW35_12075 616152d2e8167bfbe72e346911cd4f07 352 PIRSF PIRSF005096 2 348 7.2E-128 T 12-10-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 HW35_06005 e46219f093b3c0bb5b404cf7c4a8bbcf 327 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 119 3.3E-29 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 HW35_06005 e46219f093b3c0bb5b404cf7c4a8bbcf 327 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 308 2.1E-56 T 12-10-2018 IPR005218 Diacylglycerol/lipid kinase HW35_06005 e46219f093b3c0bb5b404cf7c4a8bbcf 327 Gene3D G3DSA:2.60.200.40 129 294 8.3E-84 T 12-10-2018 HW35_06005 e46219f093b3c0bb5b404cf7c4a8bbcf 327 Gene3D G3DSA:3.40.50.10330 6 128 8.3E-84 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 HW35_06005 e46219f093b3c0bb5b404cf7c4a8bbcf 327 SUPERFAMILY SSF111331 1 310 2.75E-77 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily HW35_06005 e46219f093b3c0bb5b404cf7c4a8bbcf 327 SMART SM00046 3 131 6.8E-9 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 HW35_16685 cf925044a70f16b77a45d6802bd9b98b 76 SUPERFAMILY SSF54814 15 59 4.9E-7 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 HW35_16685 cf925044a70f16b77a45d6802bd9b98b 76 Hamap MF_00088 UPF0109 protein . 1 75 21.833 T 12-10-2018 IPR020627 Uncharacterised protein family UPF0109 HW35_16685 cf925044a70f16b77a45d6802bd9b98b 76 Pfam PF13083 KH domain 2 74 2.2E-22 T 12-10-2018 HW35_04075 bca020a485d819adc5b166414259ceb3 314 Pfam PF07136 Protein of unknown function (DUF1385) 56 299 1.7E-79 T 12-10-2018 IPR010787 Protein of unknown function DUF1385 HW35_04075 bca020a485d819adc5b166414259ceb3 314 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 56 291 1.0E-82 T 12-10-2018 IPR010787 Protein of unknown function DUF1385 HW35_13625 2485131f013d49b92d16c415c82c4c79 442 Pfam PF00665 Integrase core domain 280 395 1.6E-21 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_13625 2485131f013d49b92d16c415c82c4c79 442 Gene3D G3DSA:3.30.420.10 274 439 1.7E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_13625 2485131f013d49b92d16c415c82c4c79 442 Pfam PF13276 HTH-like domain 195 250 1.3E-12 T 12-10-2018 IPR025948 HTH-like domain HW35_13625 2485131f013d49b92d16c415c82c4c79 442 SUPERFAMILY SSF53098 272 437 1.67E-28 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_11705 ee224dc624e856dfc1d1778469fc79cf 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 205 2.0E-45 T 12-10-2018 HW35_11705 ee224dc624e856dfc1d1778469fc79cf 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 217 45.326 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HW35_11705 ee224dc624e856dfc1d1778469fc79cf 227 PIRSF PIRSF001586 1 222 2.1E-91 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HW35_11705 ee224dc624e856dfc1d1778469fc79cf 227 SMART SM01211 1 219 9.1E-139 T 12-10-2018 HW35_11705 ee224dc624e856dfc1d1778469fc79cf 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 2.6E-96 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HW35_11705 ee224dc624e856dfc1d1778469fc79cf 227 SUPERFAMILY SSF52317 2 219 3.06E-78 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_11705 ee224dc624e856dfc1d1778469fc79cf 227 Gene3D G3DSA:3.40.50.880 1 220 1.7E-75 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_07005 31beb8439533027add45400da5294455 305 TIGRFAM TIGR00510 lipA: lipoyl synthase 3 293 3.8E-124 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 HW35_07005 31beb8439533027add45400da5294455 305 SUPERFAMILY SSF102114 20 287 5.1E-65 T 12-10-2018 HW35_07005 31beb8439533027add45400da5294455 305 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 3 45 6.5E-11 T 12-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 HW35_07005 31beb8439533027add45400da5294455 305 Gene3D G3DSA:3.20.20.70 2 268 3.3E-22 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_07005 31beb8439533027add45400da5294455 305 Pfam PF04055 Radical SAM superfamily 64 224 1.0E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_07005 31beb8439533027add45400da5294455 305 SMART SM00729 57 265 1.4E-15 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HW35_07005 31beb8439533027add45400da5294455 305 Hamap MF_00206 Lipoyl synthase [lipA]. 1 295 150.908 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 HW35_07005 31beb8439533027add45400da5294455 305 PIRSF PIRSF005963 1 305 2.6E-139 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 HW35_07420 ada92d835634b5304e3fabd8ac045e65 337 SUPERFAMILY SSF46785 19 84 2.25E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_07420 ada92d835634b5304e3fabd8ac045e65 337 Gene3D G3DSA:1.10.10.10 17 88 2.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_07420 ada92d835634b5304e3fabd8ac045e65 337 SUPERFAMILY SSF100950 92 337 2.0E-67 T 12-10-2018 IPR037171 NagB/RpiA transferase-like HW35_07420 ada92d835634b5304e3fabd8ac045e65 337 Gene3D G3DSA:3.40.50.1360 89 337 2.1E-78 T 12-10-2018 HW35_07420 ada92d835634b5304e3fabd8ac045e65 337 Pfam PF04198 Putative sugar-binding domain 93 337 5.4E-69 T 12-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 HW35_01895 c4b77fcdef3a84140fcecb3a31e6aeb8 154 Pfam PF00258 Flavodoxin 5 108 1.1E-17 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 HW35_01895 c4b77fcdef3a84140fcecb3a31e6aeb8 154 Gene3D G3DSA:3.40.50.360 1 153 2.3E-25 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_01895 c4b77fcdef3a84140fcecb3a31e6aeb8 154 SUPERFAMILY SSF52218 1 140 3.52E-27 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_06060 5aee8f21250203103c69bcd6840dfe9e 146 Gene3D G3DSA:1.20.1260.120 8 146 1.5E-7 T 12-10-2018 HW35_06060 5aee8f21250203103c69bcd6840dfe9e 146 SUPERFAMILY SSF158430 1 136 1.83E-22 T 12-10-2018 HW35_06060 5aee8f21250203103c69bcd6840dfe9e 146 Pfam PF11155 Domain of unknown function (DUF2935) 13 133 4.3E-20 T 12-10-2018 IPR021328 Protein of unknown function DUF2935 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 SUPERFAMILY SSF54713 151 293 2.35E-51 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 292 1.2E-116 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 SUPERFAMILY SSF46934 1 55 7.78E-22 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 82.784 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 Gene3D G3DSA:1.10.8.10 1 55 6.0E-29 T 12-10-2018 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 SUPERFAMILY SSF54713 55 144 6.7E-22 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 Pfam PF00889 Elongation factor TS 70 274 6.1E-75 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 Gene3D G3DSA:3.30.479.20 56 146 9.5E-25 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 HW35_16770 eda300f3ef4d0dba3d7d913b9e59c579 294 Gene3D G3DSA:1.10.286.20 199 236 5.9E-20 T 12-10-2018 HW35_00610 a002ef51355de37abf0eefdc51081f66 427 Gene3D G3DSA:1.20.1250.20 10 206 3.9E-8 T 12-10-2018 HW35_00610 a002ef51355de37abf0eefdc51081f66 427 SUPERFAMILY SSF103473 12 415 2.09E-42 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_00610 a002ef51355de37abf0eefdc51081f66 427 Pfam PF11700 Vacuole effluxer Atg22 like 8 131 7.0E-12 T 12-10-2018 IPR024671 Autophagy-related protein 22-like HW35_00610 a002ef51355de37abf0eefdc51081f66 427 Pfam PF11700 Vacuole effluxer Atg22 like 138 411 8.0E-48 T 12-10-2018 IPR024671 Autophagy-related protein 22-like HW35_00610 a002ef51355de37abf0eefdc51081f66 427 Gene3D G3DSA:1.20.1250.20 226 419 4.5E-20 T 12-10-2018 HW35_02285 1817582daf729f016785ed1047263d1e 335 SUPERFAMILY SSF48452 193 326 4.49E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_02285 1817582daf729f016785ed1047263d1e 335 SMART SM00028 270 303 0.0069 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HW35_02285 1817582daf729f016785ed1047263d1e 335 Gene3D G3DSA:1.25.40.10 174 325 1.4E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_02285 1817582daf729f016785ed1047263d1e 335 Gene3D G3DSA:3.90.550.10 1 151 4.0E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_02285 1817582daf729f016785ed1047263d1e 335 SUPERFAMILY SSF53448 1 141 9.25E-27 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_02285 1817582daf729f016785ed1047263d1e 335 Pfam PF00535 Glycosyl transferase family 2 1 128 1.6E-20 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HW35_05125 b18b7d8cc19f106ce2887181130600d5 403 Gene3D G3DSA:1.20.81.30 55 172 1.4E-36 T 12-10-2018 HW35_05125 b18b7d8cc19f106ce2887181130600d5 403 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 165 193 - T 12-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 HW35_05125 b18b7d8cc19f106ce2887181130600d5 403 Gene3D G3DSA:1.20.81.30 256 367 1.3E-25 T 12-10-2018 HW35_05125 b18b7d8cc19f106ce2887181130600d5 403 Pfam PF00482 Type II secretion system (T2SS), protein F 274 395 1.1E-26 T 12-10-2018 IPR018076 Type II secretion system F domain HW35_05125 b18b7d8cc19f106ce2887181130600d5 403 Pfam PF00482 Type II secretion system (T2SS), protein F 70 193 1.3E-34 T 12-10-2018 IPR018076 Type II secretion system F domain HW35_05125 b18b7d8cc19f106ce2887181130600d5 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 368 382 6.9E-22 T 12-10-2018 IPR003004 GspF/PilC family HW35_05125 b18b7d8cc19f106ce2887181130600d5 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 384 403 6.9E-22 T 12-10-2018 IPR003004 GspF/PilC family HW35_05125 b18b7d8cc19f106ce2887181130600d5 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 66 78 6.9E-22 T 12-10-2018 IPR003004 GspF/PilC family HW35_05125 b18b7d8cc19f106ce2887181130600d5 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 165 193 6.9E-22 T 12-10-2018 IPR003004 GspF/PilC family HW35_02985 d85e86d3827ba2a7e6b7ce6656cf4246 163 Pfam PF02681 Divergent PAP2 family 2 142 1.9E-42 T 12-10-2018 IPR003832 Protein of unknown function DUF212 HW35_13365 8a029c2873d93cc05f87a9bbd27fa44c 519 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 504 5.0E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_13365 8a029c2873d93cc05f87a9bbd27fa44c 519 Pfam PF00501 AMP-binding enzyme 12 419 1.4E-107 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_13365 8a029c2873d93cc05f87a9bbd27fa44c 519 Gene3D G3DSA:3.30.300.310 416 518 4.4E-36 T 12-10-2018 HW35_13365 8a029c2873d93cc05f87a9bbd27fa44c 519 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_13365 8a029c2873d93cc05f87a9bbd27fa44c 519 Gene3D G3DSA:3.40.50.12780 4 415 1.3E-118 T 12-10-2018 HW35_13365 8a029c2873d93cc05f87a9bbd27fa44c 519 SUPERFAMILY SSF56801 4 516 6.02E-155 T 12-10-2018 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 SUPERFAMILY SSF46911 5 76 1.44E-31 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 76 1.0E-23 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 12-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 3.6E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 3.6E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 3.6E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 3.6E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 Pfam PF01084 Ribosomal protein S18 22 72 4.6E-29 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 Gene3D G3DSA:4.10.640.10 2 77 1.2E-31 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 76 2.4E-38 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09875 5e7f06183beae8d7e41bcf0c685c1d22 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 77 22.837 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_12525 7a588b1ea9d79ae4a9dfbe67873194dc 317 Gene3D G3DSA:3.40.50.2300 45 296 2.1E-87 T 12-10-2018 HW35_12525 7a588b1ea9d79ae4a9dfbe67873194dc 317 Pfam PF13407 Periplasmic binding protein domain 38 288 1.3E-62 T 12-10-2018 IPR025997 Periplasmic binding protein HW35_12525 7a588b1ea9d79ae4a9dfbe67873194dc 317 SUPERFAMILY SSF53822 38 307 6.6E-76 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_12525 7a588b1ea9d79ae4a9dfbe67873194dc 317 Gene3D G3DSA:3.40.50.2300 137 304 2.1E-87 T 12-10-2018 HW35_17600 b13c64d9982c95a95a82f2cc272d7644 337 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_17600 b13c64d9982c95a95a82f2cc272d7644 337 SUPERFAMILY SSF52540 6 251 2.18E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17600 b13c64d9982c95a95a82f2cc272d7644 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 298 2.5E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_17600 b13c64d9982c95a95a82f2cc272d7644 337 SMART SM00382 36 231 5.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_17600 b13c64d9982c95a95a82f2cc272d7644 337 Gene3D G3DSA:3.40.50.300 4 333 8.3E-103 T 12-10-2018 HW35_17600 b13c64d9982c95a95a82f2cc272d7644 337 Pfam PF00005 ABC transporter 28 179 8.7E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_17600 b13c64d9982c95a95a82f2cc272d7644 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 318 1.0E-28 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_17160 7c76fd2053e94df45514110e772d8813 418 Hamap MF_00900 GTPase HflX [hflX]. 28 386 47.576 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 HW35_17160 7c76fd2053e94df45514110e772d8813 418 Pfam PF16360 GTP-binding GTPase Middle Region 115 193 1.1E-31 T 12-10-2018 IPR032305 GTP-binding protein, middle domain HW35_17160 7c76fd2053e94df45514110e772d8813 418 SUPERFAMILY SSF52540 198 368 3.2E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17160 7c76fd2053e94df45514110e772d8813 418 PIRSF PIRSF006809 1 417 2.5E-151 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 HW35_17160 7c76fd2053e94df45514110e772d8813 418 Pfam PF01926 50S ribosome-binding GTPase 200 319 5.6E-19 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_17160 7c76fd2053e94df45514110e772d8813 418 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 9 356 2.9E-148 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 HW35_17160 7c76fd2053e94df45514110e772d8813 418 Gene3D G3DSA:3.40.50.11060 19 139 4.0E-43 T 12-10-2018 HW35_17160 7c76fd2053e94df45514110e772d8813 418 Pfam PF13167 GTP-binding GTPase N-terminal 26 113 2.0E-35 T 12-10-2018 IPR025121 GTPase HflX, N-terminal HW35_17160 7c76fd2053e94df45514110e772d8813 418 Gene3D G3DSA:3.40.50.300 200 363 1.1E-33 T 12-10-2018 HW35_17160 7c76fd2053e94df45514110e772d8813 418 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 268 286 3.3E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_17160 7c76fd2053e94df45514110e772d8813 418 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 201 221 3.3E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_10035 2648933b51ff68b37295138ea7021bac 312 Pfam PF14175 YaaC-like Protein 9 307 4.5E-102 T 12-10-2018 IPR026988 YaaC-like protein HW35_09885 6457645d8899f6a542c8388a905fd380 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 3.9E-33 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09885 6457645d8899f6a542c8388a905fd380 95 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 12-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 HW35_09885 6457645d8899f6a542c8388a905fd380 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 22.726 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 HW35_09885 6457645d8899f6a542c8388a905fd380 95 Pfam PF01250 Ribosomal protein S6 3 92 3.0E-29 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09885 6457645d8899f6a542c8388a905fd380 95 Gene3D G3DSA:3.30.70.60 1 95 5.0E-33 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 HW35_09885 6457645d8899f6a542c8388a905fd380 95 SUPERFAMILY SSF54995 1 95 7.46E-33 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_00085 76611f6f87b953657ab3d331b08a6bcb 319 Gene3D G3DSA:3.40.50.1980 184 316 1.4E-42 T 12-10-2018 HW35_00085 76611f6f87b953657ab3d331b08a6bcb 319 Pfam PF01497 Periplasmic binding protein 64 292 1.8E-44 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain HW35_00085 76611f6f87b953657ab3d331b08a6bcb 319 Gene3D G3DSA:3.40.50.1980 61 182 5.9E-40 T 12-10-2018 HW35_00085 76611f6f87b953657ab3d331b08a6bcb 319 SUPERFAMILY SSF53807 43 315 3.68E-69 T 12-10-2018 HW35_10400 fde3d61abc0b7d07469f2d1f5c8b02c3 175 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 HW35_10400 fde3d61abc0b7d07469f2d1f5c8b02c3 175 SUPERFAMILY SSF55083 4 157 1.57E-55 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 HW35_10400 fde3d61abc0b7d07469f2d1f5c8b02c3 175 Gene3D G3DSA:3.30.70.560 2 171 5.1E-58 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 HW35_10400 fde3d61abc0b7d07469f2d1f5c8b02c3 175 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 134 3.1E-46 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 HW35_10400 fde3d61abc0b7d07469f2d1f5c8b02c3 175 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 134 3.4E-39 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 SUPERFAMILY SSF51735 2 250 5.75E-64 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 Gene3D G3DSA:3.40.50.720 1 260 3.9E-65 T 12-10-2018 HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_02635 0a4388cb2117f0bb44ee321bf73c4aea 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 250 4.1E-49 T 12-10-2018 HW35_03530 5252f33e98584788b746d58f05ba5a6f 194 Pfam PF12822 ECF transporter, substrate-specific component 7 171 5.3E-24 T 12-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 HW35_03530 5252f33e98584788b746d58f05ba5a6f 194 PIRSF PIRSF037778 2 184 2.6E-49 T 12-10-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 HW35_03530 5252f33e98584788b746d58f05ba5a6f 194 Gene3D G3DSA:1.10.1760.20 3 186 5.9E-52 T 12-10-2018 HW35_03055 3ac4597b31e36e04d2d711ecfe0442d6 68 SUPERFAMILY SSF64307 1 66 1.83E-14 T 12-10-2018 IPR036868 TusA-like domain superfamily HW35_03055 3ac4597b31e36e04d2d711ecfe0442d6 68 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 3 67 3.0E-20 T 12-10-2018 IPR018720 Domain of unknown function DUF2249 HW35_03055 3ac4597b31e36e04d2d711ecfe0442d6 68 Gene3D G3DSA:3.30.110.40 1 68 5.7E-7 T 12-10-2018 IPR036868 TusA-like domain superfamily HW35_16260 a1459a9bde33b3a37e8c6b7cf535d9b3 513 Gene3D G3DSA:3.90.226.10 250 511 6.8E-86 T 12-10-2018 HW35_16260 a1459a9bde33b3a37e8c6b7cf535d9b3 513 Gene3D G3DSA:3.90.226.10 3 248 5.0E-79 T 12-10-2018 HW35_16260 a1459a9bde33b3a37e8c6b7cf535d9b3 513 Pfam PF01039 Carboxyl transferase domain 32 510 5.2E-157 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 HW35_16260 a1459a9bde33b3a37e8c6b7cf535d9b3 513 SUPERFAMILY SSF52096 7 250 2.56E-67 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_16260 a1459a9bde33b3a37e8c6b7cf535d9b3 513 SUPERFAMILY SSF52096 259 511 2.93E-82 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_00620 d547d01ef38424700be344d2cf4b30a0 127 SUPERFAMILY SSF56672 20 125 9.34E-15 T 12-10-2018 HW35_00620 d547d01ef38424700be344d2cf4b30a0 127 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 66 123 2.5E-11 T 12-10-2018 IPR000477 Reverse transcriptase domain HW35_15320 be448f1c9a5d88ad11557f2ea2c8ebf5 347 SMART SM00382 33 241 2.6E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_15320 be448f1c9a5d88ad11557f2ea2c8ebf5 347 SUPERFAMILY SSF52540 4 254 2.78E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15320 be448f1c9a5d88ad11557f2ea2c8ebf5 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 9.0E-21 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_15320 be448f1c9a5d88ad11557f2ea2c8ebf5 347 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_15320 be448f1c9a5d88ad11557f2ea2c8ebf5 347 Gene3D G3DSA:3.40.50.300 1 328 1.2E-101 T 12-10-2018 HW35_15320 be448f1c9a5d88ad11557f2ea2c8ebf5 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 297 4.7E-15 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HW35_15320 be448f1c9a5d88ad11557f2ea2c8ebf5 347 Pfam PF00005 ABC transporter 25 183 8.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_09735 a1922b762b4ec628f86815561d7ed032 488 Pfam PF00501 AMP-binding enzyme 10 390 4.4E-59 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HW35_09735 a1922b762b4ec628f86815561d7ed032 488 Gene3D G3DSA:3.30.300.310 389 487 4.5E-26 T 12-10-2018 HW35_09735 a1922b762b4ec628f86815561d7ed032 488 Pfam PF13193 AMP-binding enzyme C-terminal domain 400 471 1.5E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HW35_09735 a1922b762b4ec628f86815561d7ed032 488 ProSitePatterns PS00455 Putative AMP-binding domain signature. 148 159 - T 12-10-2018 IPR020845 AMP-binding, conserved site HW35_09735 a1922b762b4ec628f86815561d7ed032 488 SUPERFAMILY SSF56801 4 483 6.15E-103 T 12-10-2018 HW35_09735 a1922b762b4ec628f86815561d7ed032 488 Gene3D G3DSA:3.40.50.12780 2 388 1.7E-71 T 12-10-2018 HW35_14885 41f77f2a566ed8ac7dfa9f1e98ee162f 995 Gene3D G3DSA:3.40.50.300 730 993 7.0E-14 T 12-10-2018 HW35_14885 41f77f2a566ed8ac7dfa9f1e98ee162f 995 Gene3D G3DSA:3.40.50.300 1 276 7.1E-18 T 12-10-2018 HW35_14885 41f77f2a566ed8ac7dfa9f1e98ee162f 995 SUPERFAMILY SSF52540 1 975 1.1E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_14885 41f77f2a566ed8ac7dfa9f1e98ee162f 995 Pfam PF13514 AAA domain 1 206 8.9E-24 T 12-10-2018 IPR038734 Uncharacterized protein YhaN, AAA domain HW35_12225 e2ade018826693cd8fe06832c8aacd3f 336 Gene3D G3DSA:1.10.3470.10 7 334 1.6E-88 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_12225 e2ade018826693cd8fe06832c8aacd3f 336 Pfam PF01032 FecCD transport family 22 330 3.9E-88 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 HW35_12225 e2ade018826693cd8fe06832c8aacd3f 336 SUPERFAMILY SSF81345 8 330 6.8E-81 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_07515 c43e35b9f64cb831fd53f58927e9b2ea 874 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 30 860 3.4E-268 T 12-10-2018 IPR018752 Uncharacterised protein family UPF0753 HW35_07515 c43e35b9f64cb831fd53f58927e9b2ea 874 Hamap MF_01871 UPF0753 protein . 25 874 24.071 T 12-10-2018 IPR018752 Uncharacterised protein family UPF0753 HW35_05235 98f67572c3bb76768b0e33ba127ba0ce 277 Pfam PF01578 Cytochrome C assembly protein 69 267 3.5E-30 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 HW35_15245 2c57e2e1d0cd617dffb0e3ba687ff754 315 Gene3D G3DSA:3.40.50.2300 132 298 6.0E-82 T 12-10-2018 HW35_15245 2c57e2e1d0cd617dffb0e3ba687ff754 315 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 28 314 1.4E-66 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 HW35_15245 2c57e2e1d0cd617dffb0e3ba687ff754 315 SUPERFAMILY SSF53822 28 233 2.02E-16 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_15245 2c57e2e1d0cd617dffb0e3ba687ff754 315 Gene3D G3DSA:3.40.50.2300 40 282 6.0E-82 T 12-10-2018 HW35_16250 2504144ed76dbf97d699eab9cdb5a5c0 445 SUPERFAMILY SSF56059 82 346 8.92E-70 T 12-10-2018 HW35_16250 2504144ed76dbf97d699eab9cdb5a5c0 445 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16250 2504144ed76dbf97d699eab9cdb5a5c0 445 SUPERFAMILY SSF51246 331 441 2.2E-35 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 HW35_16250 2504144ed76dbf97d699eab9cdb5a5c0 445 Pfam PF02785 Biotin carboxylase C-terminal domain 335 440 1.1E-34 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_16250 2504144ed76dbf97d699eab9cdb5a5c0 445 SMART SM00878 335 440 7.3E-43 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_16250 2504144ed76dbf97d699eab9cdb5a5c0 445 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_16250 2504144ed76dbf97d699eab9cdb5a5c0 445 Gene3D G3DSA:3.30.470.130 1 445 4.6E-194 T 12-10-2018 HW35_16250 2504144ed76dbf97d699eab9cdb5a5c0 445 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 2.0E-44 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HW35_16250 2504144ed76dbf97d699eab9cdb5a5c0 445 SUPERFAMILY SSF52440 2 112 6.91E-46 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HW35_16250 2504144ed76dbf97d699eab9cdb5a5c0 445 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 321 1.9E-77 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HW35_10920 55cc331accd57af44bab24c5449c3ff9 105 TIGRFAM TIGR03651 circ_ocin_uber: circular bacteriocin, circularin A/uberolysin family 35 105 1.3E-10 T 12-10-2018 IPR020038 Circular bacteriocin, circularin A/uberolysin family HW35_10920 55cc331accd57af44bab24c5449c3ff9 105 Pfam PF09221 Bacteriocin class IId cyclical uberolysin-like 39 105 1.7E-5 T 12-10-2018 IPR020038 Circular bacteriocin, circularin A/uberolysin family HW35_10920 55cc331accd57af44bab24c5449c3ff9 105 SUPERFAMILY SSF47869 36 105 2.62E-16 T 12-10-2018 HW35_10920 55cc331accd57af44bab24c5449c3ff9 105 Gene3D G3DSA:1.20.225.10 36 105 6.2E-25 T 12-10-2018 IPR009086 Bacteriocin AS-48 HW35_17650 5c0c14b23b11774cedb3b8067ca558ac 173 Gene3D G3DSA:3.40.630.30 20 153 4.6E-25 T 12-10-2018 HW35_17650 5c0c14b23b11774cedb3b8067ca558ac 173 Pfam PF13302 Acetyltransferase (GNAT) domain 19 151 3.6E-14 T 12-10-2018 IPR000182 GNAT domain HW35_17650 5c0c14b23b11774cedb3b8067ca558ac 173 SUPERFAMILY SSF55729 14 155 1.95E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_12150 e17aef1fd7dc388d0f35f465b724b7cc 66 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 8.6E-7 T 12-10-2018 HW35_12150 e17aef1fd7dc388d0f35f465b724b7cc 66 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 8.6E-7 T 12-10-2018 HW35_12150 e17aef1fd7dc388d0f35f465b724b7cc 66 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 48 6.8E-20 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HW35_12150 e17aef1fd7dc388d0f35f465b724b7cc 66 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 65 16.973 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HW35_12150 e17aef1fd7dc388d0f35f465b724b7cc 66 Pfam PF02416 mttA/Hcf106 family 5 54 3.3E-22 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 HW35_01105 1ea45b6886029817714659cb06910acc 514 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 514 67.277 T 12-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 HW35_01105 1ea45b6886029817714659cb06910acc 514 SUPERFAMILY SSF53720 3 510 1.27E-158 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HW35_01105 1ea45b6886029817714659cb06910acc 514 Pfam PF00171 Aldehyde dehydrogenase family 48 509 1.7E-161 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 HW35_01105 1ea45b6886029817714659cb06910acc 514 Gene3D G3DSA:3.40.605.10 8 509 9.1E-193 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_01105 1ea45b6886029817714659cb06910acc 514 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 312 323 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 HW35_01105 1ea45b6886029817714659cb06910acc 514 Gene3D G3DSA:3.40.309.10 289 479 9.1E-193 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 HW35_01105 1ea45b6886029817714659cb06910acc 514 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 284 291 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 HW35_01105 1ea45b6886029817714659cb06910acc 514 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 4 513 5.8E-261 T 12-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 HW35_06730 0c9babd7f44f7727dc8c4060477a6bc6 298 SUPERFAMILY SSF161111 6 212 2.35E-50 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily HW35_06730 0c9babd7f44f7727dc8c4060477a6bc6 298 SUPERFAMILY SSF160240 215 293 7.06E-16 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 HW35_06730 0c9babd7f44f7727dc8c4060477a6bc6 298 Gene3D G3DSA:3.30.70.1350 212 293 4.0E-17 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 HW35_06730 0c9babd7f44f7727dc8c4060477a6bc6 298 Pfam PF01545 Cation efflux family 13 211 3.6E-43 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HW35_06730 0c9babd7f44f7727dc8c4060477a6bc6 298 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 9 293 7.8E-70 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HW35_06730 0c9babd7f44f7727dc8c4060477a6bc6 298 Pfam PF16916 Dimerisation domain of Zinc Transporter 217 293 4.5E-18 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain HW35_06730 0c9babd7f44f7727dc8c4060477a6bc6 298 Gene3D G3DSA:1.20.1510.10 7 211 1.7E-53 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily HW35_11565 9ba429172a1231de748636852d33cb59 218 SMART SM00881 81 182 2.8E-20 T 12-10-2018 IPR003781 CoA-binding GO:0048037 HW35_11565 9ba429172a1231de748636852d33cb59 218 Pfam PF02629 CoA binding domain 84 180 2.5E-27 T 12-10-2018 IPR003781 CoA-binding GO:0048037 HW35_11565 9ba429172a1231de748636852d33cb59 218 Gene3D G3DSA:1.10.10.10 1 82 7.9E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_11565 9ba429172a1231de748636852d33cb59 218 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 211 38.991 T 12-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 HW35_11565 9ba429172a1231de748636852d33cb59 218 Gene3D G3DSA:3.40.50.720 83 217 7.1E-47 T 12-10-2018 HW35_11565 9ba429172a1231de748636852d33cb59 218 SUPERFAMILY SSF46785 9 80 1.36E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_11565 9ba429172a1231de748636852d33cb59 218 Pfam PF06971 Putative DNA-binding protein N-terminus 7 55 4.1E-19 T 12-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 HW35_11565 9ba429172a1231de748636852d33cb59 218 SUPERFAMILY SSF51735 84 209 4.95E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_17680 dec2d7ffc641f3f646e699fca64a31fd 391 Gene3D G3DSA:3.90.230.10 162 390 2.4E-43 T 12-10-2018 HW35_17680 dec2d7ffc641f3f646e699fca64a31fd 391 SUPERFAMILY SSF53092 1 156 1.05E-36 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HW35_17680 dec2d7ffc641f3f646e699fca64a31fd 391 Gene3D G3DSA:3.40.350.10 1 156 1.8E-35 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HW35_17680 dec2d7ffc641f3f646e699fca64a31fd 391 Pfam PF00557 Metallopeptidase family M24 166 375 7.0E-34 T 12-10-2018 IPR000994 Peptidase M24 HW35_17680 dec2d7ffc641f3f646e699fca64a31fd 391 Pfam PF01321 Creatinase/Prolidase N-terminal domain 12 156 3.2E-21 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 HW35_17680 dec2d7ffc641f3f646e699fca64a31fd 391 SUPERFAMILY SSF55920 159 390 1.44E-55 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like HW35_05775 059a458ade2c944005f17bb20e65b23a 148 Gene3D G3DSA:3.40.50.620 7 144 1.2E-41 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_05775 059a458ade2c944005f17bb20e65b23a 148 SUPERFAMILY SSF52402 5 144 3.6E-36 T 12-10-2018 HW35_05775 059a458ade2c944005f17bb20e65b23a 148 Pfam PF00582 Universal stress protein family 5 144 3.2E-34 T 12-10-2018 IPR006016 UspA HW35_05775 059a458ade2c944005f17bb20e65b23a 148 PRINTS PR01438 Universal stress protein signature 104 116 1.3E-17 T 12-10-2018 IPR006015 Universal stress protein A HW35_05775 059a458ade2c944005f17bb20e65b23a 148 PRINTS PR01438 Universal stress protein signature 122 144 1.3E-17 T 12-10-2018 IPR006015 Universal stress protein A HW35_05775 059a458ade2c944005f17bb20e65b23a 148 PRINTS PR01438 Universal stress protein signature 5 23 1.3E-17 T 12-10-2018 IPR006015 Universal stress protein A HW35_05775 059a458ade2c944005f17bb20e65b23a 148 PIRSF PIRSF006276 3 147 1.1E-22 T 12-10-2018 IPR006015 Universal stress protein A HW35_08045 3e92040ddbbee172e421b13698938d68 323 SUPERFAMILY SSF103481 77 157 1.26E-7 T 12-10-2018 HW35_08045 3e92040ddbbee172e421b13698938d68 323 Pfam PF00892 EamA-like transporter family 167 305 1.2E-8 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_08045 3e92040ddbbee172e421b13698938d68 323 Pfam PF00892 EamA-like transporter family 6 153 7.9E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 185 325 3.7E-56 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 SUPERFAMILY SSF48179 185 337 9.52E-60 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 Gene3D G3DSA:1.10.1040.10 194 342 2.8E-54 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 165 4.9E-55 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 Gene3D G3DSA:3.40.50.720 1 192 1.4E-65 T 12-10-2018 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 193 214 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 10 27 2.4E-47 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 60 87 2.4E-47 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 243 260 2.4E-47 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 178 202 2.4E-47 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 138 158 2.4E-47 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 203 227 2.4E-47 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 PIRSF PIRSF000114 1 337 3.9E-114 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 SUPERFAMILY SSF51735 8 183 8.24E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_03395 a810afb359e3175aba93d26ea13a0e04 349 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 6 327 39.192 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HW35_07360 ea0297a00c2927d57d28630355f64867 780 Hamap MF_01895 Ribonuclease R [rnr]. 27 710 61.77 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 HW35_07360 ea0297a00c2927d57d28630355f64867 780 Pfam PF00575 S1 RNA binding domain 627 709 6.3E-17 T 12-10-2018 IPR003029 S1 domain GO:0003676 HW35_07360 ea0297a00c2927d57d28630355f64867 780 Gene3D G3DSA:2.40.50.140 631 779 2.4E-26 T 12-10-2018 HW35_07360 ea0297a00c2927d57d28630355f64867 780 ProSitePatterns PS01175 Ribonuclease II family signature. 547 571 - T 12-10-2018 IPR022966 Ribonuclease II/R, conserved site HW35_07360 ea0297a00c2927d57d28630355f64867 780 SUPERFAMILY SSF50249 128 227 5.77E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_07360 ea0297a00c2927d57d28630355f64867 780 SMART SM00316 628 710 4.2E-22 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_07360 ea0297a00c2927d57d28630355f64867 780 Pfam PF00773 RNB domain 250 578 1.3E-114 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 HW35_07360 ea0297a00c2927d57d28630355f64867 780 SMART SM00955 250 580 9.4E-182 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 HW35_07360 ea0297a00c2927d57d28630355f64867 780 Gene3D G3DSA:2.40.50.140 62 137 1.1E-19 T 12-10-2018 HW35_07360 ea0297a00c2927d57d28630355f64867 780 Gene3D G3DSA:2.40.50.140 139 205 4.3E-10 T 12-10-2018 HW35_07360 ea0297a00c2927d57d28630355f64867 780 SUPERFAMILY SSF50249 628 709 1.86E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_07360 ea0297a00c2927d57d28630355f64867 780 Pfam PF08206 Ribonuclease B OB domain 149 203 8.1E-11 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain HW35_07360 ea0297a00c2927d57d28630355f64867 780 Pfam PF08206 Ribonuclease B OB domain 76 134 1.5E-23 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain HW35_07360 ea0297a00c2927d57d28630355f64867 780 SUPERFAMILY SSF50249 210 627 3.14E-149 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_07360 ea0297a00c2927d57d28630355f64867 780 SMART SM00357 75 135 5.9E-11 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 HW35_07360 ea0297a00c2927d57d28630355f64867 780 SMART SM00357 140 204 3.2E-8 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 HW35_07360 ea0297a00c2927d57d28630355f64867 780 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 60 710 8.0E-251 T 12-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 HW35_07360 ea0297a00c2927d57d28630355f64867 780 TIGRFAM TIGR02063 RNase_R: ribonuclease R 11 710 1.1E-290 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 HW35_07360 ea0297a00c2927d57d28630355f64867 780 SUPERFAMILY SSF50249 57 137 2.66E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_06835 660465ee0e7516a04cb509ac8bc1d8c3 87 ProDom PD062625 YUGE 11 87 2.0E-17 T 12-10-2018 IPR015053 Protein of unknown function DUF1871 HW35_06835 660465ee0e7516a04cb509ac8bc1d8c3 87 Gene3D G3DSA:1.10.340.20 1 87 1.2E-35 T 12-10-2018 IPR023162 Apc36109-like domain superfamily HW35_06835 660465ee0e7516a04cb509ac8bc1d8c3 87 Pfam PF08958 Domain of unknown function (DUF1871) 11 85 8.8E-32 T 12-10-2018 IPR015053 Protein of unknown function DUF1871 HW35_06835 660465ee0e7516a04cb509ac8bc1d8c3 87 SUPERFAMILY SSF116922 6 83 8.63E-25 T 12-10-2018 IPR023162 Apc36109-like domain superfamily HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 Gene3D G3DSA:3.30.870.10 135 323 5.1E-48 T 12-10-2018 HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 33 503 2.5E-191 T 12-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 Pfam PF13091 PLD-like domain 156 299 1.1E-15 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 Pfam PF13091 PLD-like domain 346 467 5.4E-26 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 Pfam PF13396 Phospholipase_D-nuclease N-terminal 39 81 1.7E-8 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 SMART SM00155 416 443 3.7E-7 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 SMART SM00155 239 266 2.4E-5 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 SUPERFAMILY SSF56024 291 490 6.5E-47 T 12-10-2018 HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 Hamap MF_01916 Cardiolipin synthase. 33 503 43.488 T 12-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 Gene3D G3DSA:3.30.870.10 334 477 1.0E-26 T 12-10-2018 HW35_15345 dada3cb730a121a93d9f99669c4a5fe9 503 SUPERFAMILY SSF56024 133 333 6.28E-53 T 12-10-2018 HW35_05470 27cd892a433d1752d41341efb791ab12 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 82 2.6E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_05470 27cd892a433d1752d41341efb791ab12 221 Gene3D G3DSA:1.10.357.10 76 218 4.1E-37 T 12-10-2018 HW35_05470 27cd892a433d1752d41341efb791ab12 221 SUPERFAMILY SSF46689 33 108 4.94E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_05470 27cd892a433d1752d41341efb791ab12 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 50 1.7E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_05470 27cd892a433d1752d41341efb791ab12 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 58 81 1.7E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_05470 27cd892a433d1752d41341efb791ab12 221 Pfam PF08359 YsiA-like protein, C-terminal region 84 216 1.6E-62 T 12-10-2018 IPR013570 Transcription regulator YsiA, C-terminal HW35_05470 27cd892a433d1752d41341efb791ab12 221 Gene3D G3DSA:1.10.10.60 25 75 1.5E-22 T 12-10-2018 HW35_05470 27cd892a433d1752d41341efb791ab12 221 SUPERFAMILY SSF48498 104 218 2.5E-27 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily HW35_04455 b0ac1c8c25b8f19eada1840a3418c023 250 SUPERFAMILY SSF50249 3 77 9.77E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_04455 b0ac1c8c25b8f19eada1840a3418c023 250 Pfam PF11967 Recombination protein O N terminal 4 77 2.1E-24 T 12-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal HW35_04455 b0ac1c8c25b8f19eada1840a3418c023 250 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 243 3.9E-80 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HW35_04455 b0ac1c8c25b8f19eada1840a3418c023 250 Gene3D G3DSA:1.20.1440.120 88 225 2.2E-20 T 12-10-2018 HW35_04455 b0ac1c8c25b8f19eada1840a3418c023 250 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 30.289 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HW35_04455 b0ac1c8c25b8f19eada1840a3418c023 250 Gene3D G3DSA:3.30.60.100 146 185 2.2E-20 T 12-10-2018 HW35_04455 b0ac1c8c25b8f19eada1840a3418c023 250 SUPERFAMILY SSF57863 81 232 2.62E-49 T 12-10-2018 IPR037278 ARFGAP/RecO-like zinc finger HW35_04455 b0ac1c8c25b8f19eada1840a3418c023 250 Gene3D G3DSA:2.40.50.140 2 81 9.3E-14 T 12-10-2018 HW35_04455 b0ac1c8c25b8f19eada1840a3418c023 250 Pfam PF02565 Recombination protein O C terminal 83 237 1.0E-42 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HW35_08655 259a4b320642e086c9a29ae25dc32380 310 Pfam PF00082 Subtilase family 42 279 3.2E-53 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HW35_08655 259a4b320642e086c9a29ae25dc32380 310 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 250 260 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site HW35_08655 259a4b320642e086c9a29ae25dc32380 310 Gene3D G3DSA:3.40.50.200 6 309 6.2E-103 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 HW35_08655 259a4b320642e086c9a29ae25dc32380 310 PRINTS PR00723 Subtilisin serine protease family (S8) signature 42 61 1.7E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_08655 259a4b320642e086c9a29ae25dc32380 310 PRINTS PR00723 Subtilisin serine protease family (S8) signature 84 97 1.7E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_08655 259a4b320642e086c9a29ae25dc32380 310 PRINTS PR00723 Subtilisin serine protease family (S8) signature 249 265 1.7E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_08655 259a4b320642e086c9a29ae25dc32380 310 SUPERFAMILY SSF52743 23 308 1.31E-83 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 HW35_08655 259a4b320642e086c9a29ae25dc32380 310 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 88 98 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 457 34.921 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 Pfam PF01225 Mur ligase family, catalytic domain 27 101 4.4E-14 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 Pfam PF02875 Mur ligase family, glutamate ligase domain 319 396 1.9E-13 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 SUPERFAMILY SSF63418 3 102 9.02E-26 T 12-10-2018 IPR035911 MurE/MurF, N-terminal HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 Gene3D G3DSA:3.40.1390.10 2 81 7.8E-26 T 12-10-2018 HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 Pfam PF08245 Mur ligase middle domain 111 297 1.8E-45 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 Gene3D G3DSA:3.40.1190.10 87 315 2.9E-64 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 SUPERFAMILY SSF53244 317 456 3.48E-36 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 SUPERFAMILY SSF53623 106 314 2.49E-51 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 Gene3D G3DSA:3.90.190.20 316 458 1.3E-44 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HW35_11390 468bc2ba25d4ddc0670e6028b0fc8128 458 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 455 1.9E-137 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_11320 bba9ffc790cd7d50d44fb15ded7faef8 288 SUPERFAMILY SSF117892 94 224 1.2E-14 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily HW35_11320 bba9ffc790cd7d50d44fb15ded7faef8 288 SMART SM00244 56 221 6.6E-11 T 12-10-2018 IPR001107 Band 7 domain HW35_11320 bba9ffc790cd7d50d44fb15ded7faef8 288 Pfam PF01145 SPFH domain / Band 7 family 60 230 3.7E-25 T 12-10-2018 IPR001107 Band 7 domain HW35_11320 bba9ffc790cd7d50d44fb15ded7faef8 288 Gene3D G3DSA:3.30.479.30 90 223 1.6E-11 T 12-10-2018 HW35_14305 39da8b311fbbac73147718614211a6be 130 Gene3D G3DSA:1.10.287.70 28 128 2.6E-12 T 12-10-2018 HW35_14305 39da8b311fbbac73147718614211a6be 130 Pfam PF07885 Ion channel 45 124 2.6E-12 T 12-10-2018 IPR013099 Potassium channel domain HW35_14305 39da8b311fbbac73147718614211a6be 130 SUPERFAMILY SSF81324 31 125 4.84E-10 T 12-10-2018 HW35_09505 e5b65a389186dd725d858e1f983c844b 284 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 253 3.7E-30 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 HW35_09505 e5b65a389186dd725d858e1f983c844b 284 Gene3D G3DSA:3.40.50.1000 3 276 1.3E-88 T 12-10-2018 IPR023214 HAD superfamily HW35_09505 e5b65a389186dd725d858e1f983c844b 284 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 280 3.4E-64 T 12-10-2018 IPR000150 Cof family GO:0016787 HW35_09505 e5b65a389186dd725d858e1f983c844b 284 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 280 1.7E-70 T 12-10-2018 HW35_09505 e5b65a389186dd725d858e1f983c844b 284 Gene3D G3DSA:3.30.1240.10 82 209 1.3E-88 T 12-10-2018 HW35_09505 e5b65a389186dd725d858e1f983c844b 284 SUPERFAMILY SSF56784 1 283 9.29E-70 T 12-10-2018 IPR036412 HAD-like superfamily HW35_04675 d51bedf92b2f6705065e5a26c21d5453 179 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 23 174 2.2E-37 T 12-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 HW35_04675 d51bedf92b2f6705065e5a26c21d5453 179 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HW35_04675 d51bedf92b2f6705065e5a26c21d5453 179 Gene3D G3DSA:1.20.120.1760 9 178 1.1E-12 T 12-10-2018 HW35_04675 d51bedf92b2f6705065e5a26c21d5453 179 Pfam PF01066 CDP-alcohol phosphatidyltransferase 18 81 1.8E-14 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HW35_12875 76f85b349a4990d2f417c03ffae364d9 198 PIRSF PIRSF021308 1 198 7.1E-93 T 12-10-2018 IPR016786 Uncharacterised protein YdeI, bacterial HW35_12875 76f85b349a4990d2f417c03ffae364d9 198 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 133 191 4.2E-19 T 12-10-2018 HW35_12875 76f85b349a4990d2f417c03ffae364d9 198 SUPERFAMILY SSF159888 9 119 1.96E-22 T 12-10-2018 HW35_12875 76f85b349a4990d2f417c03ffae364d9 198 Pfam PF08818 Domain of unknown function (DU1801) 20 117 1.7E-14 T 12-10-2018 IPR014922 Domain of unknown function DUF1801 HW35_17480 f38e1dfabfbcfba5b9e4499c21ff9c2c 237 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 41 213 2.1E-50 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 HW35_17480 f38e1dfabfbcfba5b9e4499c21ff9c2c 237 SUPERFAMILY SSF52402 17 201 7.85E-49 T 12-10-2018 HW35_17480 f38e1dfabfbcfba5b9e4499c21ff9c2c 237 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 47 235 1.8E-75 T 12-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 HW35_17480 f38e1dfabfbcfba5b9e4499c21ff9c2c 237 PIRSF PIRSF000857 4 237 5.9E-89 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 HW35_17480 f38e1dfabfbcfba5b9e4499c21ff9c2c 237 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 27 236 1.7E-89 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 HW35_17480 f38e1dfabfbcfba5b9e4499c21ff9c2c 237 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 4 237 41.242 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 HW35_17480 f38e1dfabfbcfba5b9e4499c21ff9c2c 237 Gene3D G3DSA:3.40.50.620 8 237 8.8E-75 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_02785 037f29a38df37b1f4d868f518224418b 274 Gene3D G3DSA:3.40.50.1110 16 256 4.2E-39 T 12-10-2018 IPR036514 SGNH hydrolase superfamily HW35_02785 037f29a38df37b1f4d868f518224418b 274 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 55 245 1.4E-28 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain HW35_02785 037f29a38df37b1f4d868f518224418b 274 SUPERFAMILY SSF52266 46 256 4.79E-38 T 12-10-2018 HW35_17690 65b2738233cb147f84e6da6ff6774ea0 334 Gene3D G3DSA:3.30.1780.10 5 322 1.3E-93 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 HW35_17690 65b2738233cb147f84e6da6ff6774ea0 334 PIRSF PIRSF001439 1 327 4.4E-79 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 HW35_17690 65b2738233cb147f84e6da6ff6774ea0 334 SUPERFAMILY SSF51735 1 331 1.57E-92 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_17690 65b2738233cb147f84e6da6ff6774ea0 334 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 4 319 1.5E-95 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 HW35_17690 65b2738233cb147f84e6da6ff6774ea0 334 Gene3D G3DSA:3.40.50.720 126 300 1.3E-93 T 12-10-2018 HW35_01325 a2412fcf0ccfd4a3a5bf9a0d84291480 294 SUPERFAMILY SSF53850 93 292 1.96E-31 T 12-10-2018 HW35_01325 a2412fcf0ccfd4a3a5bf9a0d84291480 294 SUPERFAMILY SSF46785 2 114 1.25E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_01325 a2412fcf0ccfd4a3a5bf9a0d84291480 294 Gene3D G3DSA:3.40.190.290 88 289 1.2E-69 T 12-10-2018 HW35_01325 a2412fcf0ccfd4a3a5bf9a0d84291480 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.7E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_01325 a2412fcf0ccfd4a3a5bf9a0d84291480 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_01325 a2412fcf0ccfd4a3a5bf9a0d84291480 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_01325 a2412fcf0ccfd4a3a5bf9a0d84291480 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_01325 a2412fcf0ccfd4a3a5bf9a0d84291480 294 Gene3D G3DSA:1.10.10.10 1 87 1.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_01325 a2412fcf0ccfd4a3a5bf9a0d84291480 294 Pfam PF03466 LysR substrate binding domain 92 287 1.3E-31 T 12-10-2018 IPR005119 LysR, substrate-binding HW35_08235 fb7e0e824abc2cb7f2ce5b954ff48570 348 Pfam PF00144 Beta-lactamase 10 333 5.5E-68 T 12-10-2018 IPR001466 Beta-lactamase-related HW35_08235 fb7e0e824abc2cb7f2ce5b954ff48570 348 SUPERFAMILY SSF56601 4 342 1.88E-83 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_08235 fb7e0e824abc2cb7f2ce5b954ff48570 348 Gene3D G3DSA:3.40.710.10 1 339 6.7E-83 T 12-10-2018 HW35_02725 4072902dbdc670d0f4b38382b99eb045 284 Pfam PF00583 Acetyltransferase (GNAT) family 170 232 2.5E-5 T 12-10-2018 IPR000182 GNAT domain HW35_02725 4072902dbdc670d0f4b38382b99eb045 284 SUPERFAMILY SSF55729 133 281 1.4E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_02725 4072902dbdc670d0f4b38382b99eb045 284 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 18 281 1.4E-87 T 12-10-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 HW35_02725 4072902dbdc670d0f4b38382b99eb045 284 Gene3D G3DSA:3.40.630.30 125 256 8.0E-10 T 12-10-2018 HW35_11950 de2c0b3d19c8e0d82c6fe554c3b2373c 559 SUPERFAMILY SSF81442 23 553 1.07E-97 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_11950 de2c0b3d19c8e0d82c6fe554c3b2373c 559 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 478 4.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_11950 de2c0b3d19c8e0d82c6fe554c3b2373c 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 429 450 1.9E-12 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_11950 de2c0b3d19c8e0d82c6fe554c3b2373c 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 130 142 1.9E-12 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_11950 de2c0b3d19c8e0d82c6fe554c3b2373c 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 62 85 1.9E-12 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_11950 de2c0b3d19c8e0d82c6fe554c3b2373c 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 1.9E-12 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_11950 de2c0b3d19c8e0d82c6fe554c3b2373c 559 Gene3D G3DSA:1.20.210.10 7 559 2.1E-117 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_14625 dd82e9edbba2d2a401ba494b5f45e58f 240 Pfam PF07702 UTRA domain 94 233 6.3E-46 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HW35_14625 dd82e9edbba2d2a401ba494b5f45e58f 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 4.3E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_14625 dd82e9edbba2d2a401ba494b5f45e58f 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 4.3E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_14625 dd82e9edbba2d2a401ba494b5f45e58f 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 2.5E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_14625 dd82e9edbba2d2a401ba494b5f45e58f 240 SMART SM00345 14 73 6.9E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HW35_14625 dd82e9edbba2d2a401ba494b5f45e58f 240 Gene3D G3DSA:3.40.1410.10 77 240 3.5E-59 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily HW35_14625 dd82e9edbba2d2a401ba494b5f45e58f 240 SUPERFAMILY SSF64288 61 239 1.46E-59 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily HW35_14625 dd82e9edbba2d2a401ba494b5f45e58f 240 SUPERFAMILY SSF46785 1 85 1.65E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_14625 dd82e9edbba2d2a401ba494b5f45e58f 240 Gene3D G3DSA:1.10.10.10 8 76 1.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_14625 dd82e9edbba2d2a401ba494b5f45e58f 240 SMART SM00866 94 233 2.5E-46 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HW35_03365 6b3362d71635788a6e0777cb52476235 78 Pfam PF02081 Tryptophan RNA-binding attenuator protein 8 75 7.8E-40 T 12-10-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain HW35_03365 6b3362d71635788a6e0777cb52476235 78 Hamap MF_00798 Transcription attenuation protein MtrB [mtrB]. 3 75 27.221 T 12-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 HW35_03365 6b3362d71635788a6e0777cb52476235 78 SUPERFAMILY SSF51219 9 75 1.2E-33 T 12-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily HW35_03365 6b3362d71635788a6e0777cb52476235 78 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 28 44 3.3E-34 T 12-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 HW35_03365 6b3362d71635788a6e0777cb52476235 78 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 44 60 3.3E-34 T 12-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 HW35_03365 6b3362d71635788a6e0777cb52476235 78 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 11 28 3.3E-34 T 12-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 HW35_03365 6b3362d71635788a6e0777cb52476235 78 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 60 76 3.3E-34 T 12-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 HW35_03365 6b3362d71635788a6e0777cb52476235 78 Gene3D G3DSA:2.60.40.50 1 78 1.0E-40 T 12-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily HW35_16065 a5c38a353627702659c2724c397a8f24 402 Pfam PF01098 Cell cycle protein 13 373 1.0E-107 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16065 a5c38a353627702659c2724c397a8f24 402 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 330 354 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_16875 ad09c744fb9bda83f4d9c61054ae7f28 83 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 76 1.7E-30 T 12-10-2018 IPR014238 Sporulation protein YlmC/YmxH HW35_16875 ad09c744fb9bda83f4d9c61054ae7f28 83 Gene3D G3DSA:2.30.30.240 1 79 2.4E-8 T 12-10-2018 HW35_16875 ad09c744fb9bda83f4d9c61054ae7f28 83 SUPERFAMILY SSF50346 1 75 3.69E-13 T 12-10-2018 IPR011033 PRC-barrel-like superfamily HW35_16875 ad09c744fb9bda83f4d9c61054ae7f28 83 Pfam PF05239 PRC-barrel domain 1 80 2.1E-17 T 12-10-2018 IPR027275 PRC-barrel domain HW35_15625 7c856daab6c747b6e840ece1cd8ce6c4 248 SUPERFAMILY SSF88946 20 102 2.35E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HW35_15625 7c856daab6c747b6e840ece1cd8ce6c4 248 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 20 242 1.7E-80 T 12-10-2018 IPR014244 RNA polymerase sigma-I type HW35_15625 7c856daab6c747b6e840ece1cd8ce6c4 248 Pfam PF04542 Sigma-70 region 2 34 103 4.4E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HW35_15625 7c856daab6c747b6e840ece1cd8ce6c4 248 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 14 244 28.736 T 12-10-2018 IPR014244 RNA polymerase sigma-I type HW35_15625 7c856daab6c747b6e840ece1cd8ce6c4 248 PIRSF PIRSF038953 6 247 2.2E-67 T 12-10-2018 IPR014244 RNA polymerase sigma-I type HW35_15625 7c856daab6c747b6e840ece1cd8ce6c4 248 Gene3D G3DSA:1.10.10.10 53 192 2.4E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_15625 7c856daab6c747b6e840ece1cd8ce6c4 248 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 226 1.2E-15 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HW35_16410 9a2c2f817caca9bb33c41d77a4678be2 225 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 223 4.5E-52 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 HW35_16410 9a2c2f817caca9bb33c41d77a4678be2 225 PIRSF PIRSF004848 1 224 6.1E-67 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 HW35_16410 9a2c2f817caca9bb33c41d77a4678be2 225 Gene3D G3DSA:3.20.20.10 1 225 1.4E-77 T 12-10-2018 IPR029066 PLP-binding barrel HW35_16410 9a2c2f817caca9bb33c41d77a4678be2 225 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 HW35_16410 9a2c2f817caca9bb33c41d77a4678be2 225 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 5 223 27.759 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 HW35_16410 9a2c2f817caca9bb33c41d77a4678be2 225 Pfam PF01168 Alanine racemase, N-terminal domain 9 223 1.4E-18 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HW35_16410 9a2c2f817caca9bb33c41d77a4678be2 225 SUPERFAMILY SSF51419 2 222 2.91E-74 T 12-10-2018 IPR029066 PLP-binding barrel HW35_02995 36b0124442aac7e9efc1ef7cb1daad2a 297 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 8 160 7.6E-51 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 HW35_02995 36b0124442aac7e9efc1ef7cb1daad2a 297 SUPERFAMILY SSF88723 6 159 3.43E-47 T 12-10-2018 IPR029060 PIN-like domain superfamily HW35_02995 36b0124442aac7e9efc1ef7cb1daad2a 297 SMART SM00279 179 214 1.6E-17 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 HW35_02995 36b0124442aac7e9efc1ef7cb1daad2a 297 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 178 263 1.0E-29 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 HW35_02995 36b0124442aac7e9efc1ef7cb1daad2a 297 SMART SM00475 4 267 1.0E-119 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 HW35_02995 36b0124442aac7e9efc1ef7cb1daad2a 297 SUPERFAMILY SSF47807 177 289 9.12E-30 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily HW35_02995 36b0124442aac7e9efc1ef7cb1daad2a 297 Gene3D G3DSA:1.10.150.20 180 252 2.4E-87 T 12-10-2018 HW35_02995 36b0124442aac7e9efc1ef7cb1daad2a 297 Gene3D G3DSA:3.40.50.1010 8 280 2.4E-87 T 12-10-2018 HW35_17605 025bedf47696bfd18d9b5e35d482f1e3 260 SUPERFAMILY SSF56601 3 251 3.27E-45 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_17605 025bedf47696bfd18d9b5e35d482f1e3 260 Pfam PF13354 Beta-lactamase enzyme family 27 227 9.3E-56 T 12-10-2018 HW35_17605 025bedf47696bfd18d9b5e35d482f1e3 260 Gene3D G3DSA:3.40.710.10 1 255 4.0E-66 T 12-10-2018 HW35_13130 d9b8950cc805cc56622ef2a915957ce8 432 Pfam PF13416 Bacterial extracellular solute-binding protein 58 367 2.8E-43 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein HW35_13130 d9b8950cc805cc56622ef2a915957ce8 432 Gene3D G3DSA:3.40.190.10 55 387 1.1E-69 T 12-10-2018 HW35_13130 d9b8950cc805cc56622ef2a915957ce8 432 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 144 161 - T 12-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 HW35_13130 d9b8950cc805cc56622ef2a915957ce8 432 SUPERFAMILY SSF53850 23 430 8.61E-60 T 12-10-2018 HW35_13130 d9b8950cc805cc56622ef2a915957ce8 432 Gene3D G3DSA:3.40.190.10 149 421 1.1E-69 T 12-10-2018 HW35_15410 0675fa426c55547b87130ebdd216735d 256 SUPERFAMILY SSF51735 7 255 3.04E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_15410 0675fa426c55547b87130ebdd216735d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.7E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_15410 0675fa426c55547b87130ebdd216735d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.7E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_15410 0675fa426c55547b87130ebdd216735d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.7E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_15410 0675fa426c55547b87130ebdd216735d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.7E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_15410 0675fa426c55547b87130ebdd216735d 256 Gene3D G3DSA:3.40.50.720 1 255 2.3E-61 T 12-10-2018 HW35_15410 0675fa426c55547b87130ebdd216735d 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 6.0E-89 T 12-10-2018 HW35_15410 0675fa426c55547b87130ebdd216735d 256 PIRSF PIRSF000094 2 256 1.0E-104 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1073 1250 1.2E-8 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 SUPERFAMILY SSF52980 1037 1252 9.12E-44 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 14 1258 0.0 T 12-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 Gene3D G3DSA:3.90.320.10 1016 1258 2.1E-80 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 469 9.8E-84 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 Gene3D G3DSA:3.40.50.300 272 481 5.1E-29 T 12-10-2018 HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 Gene3D G3DSA:3.40.50.300 8 205 5.3E-41 T 12-10-2018 HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 Gene3D G3DSA:3.40.50.300 780 986 2.3E-51 T 12-10-2018 HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 Gene3D G3DSA:3.40.50.300 482 779 1.4E-58 T 12-10-2018 HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 SUPERFAMILY SSF52540 6 929 1.26E-123 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 12 1258 19.962 T 12-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 HW35_15070 4a4da79e3230626b33ca87c51b8187b2 1258 Pfam PF13361 UvrD-like helicase C-terminal domain 479 906 2.6E-38 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HW35_15450 a94149bfc07888640c7e60ae5ec49172 338 Gene3D G3DSA:3.40.47.40 2 338 9.7E-148 T 12-10-2018 IPR038369 Stage V sporulation AD superfamily HW35_15450 a94149bfc07888640c7e60ae5ec49172 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 335 5.4E-154 T 12-10-2018 IPR010894 Stage V sporulation AD HW35_15450 a94149bfc07888640c7e60ae5ec49172 338 PIRSF PIRSF011570 1 338 1.0E-154 T 12-10-2018 IPR010894 Stage V sporulation AD HW35_15450 a94149bfc07888640c7e60ae5ec49172 338 SUPERFAMILY SSF53901 55 312 1.73E-14 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_15450 a94149bfc07888640c7e60ae5ec49172 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 335 1.1E-149 T 12-10-2018 IPR010894 Stage V sporulation AD HW35_04590 865a4665e9154f06212cf00d52f8c650 338 Gene3D G3DSA:3.40.50.300 1 143 9.8E-42 T 12-10-2018 HW35_04590 865a4665e9154f06212cf00d52f8c650 338 SUPERFAMILY SSF52540 6 214 5.98E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04590 865a4665e9154f06212cf00d52f8c650 338 Gene3D G3DSA:1.10.8.60 144 213 1.5E-15 T 12-10-2018 HW35_04590 865a4665e9154f06212cf00d52f8c650 338 Gene3D G3DSA:1.20.272.10 214 338 4.1E-40 T 12-10-2018 HW35_04590 865a4665e9154f06212cf00d52f8c650 338 Pfam PF06144 DNA polymerase III, delta subunit 18 194 4.7E-51 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 HW35_04590 865a4665e9154f06212cf00d52f8c650 338 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 14 336 2.6E-90 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 HW35_04590 865a4665e9154f06212cf00d52f8c650 338 SUPERFAMILY SSF48019 217 336 7.99E-27 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 HW35_11790 5f74994ca5beb90d2339135b19c22035 99 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 3 98 1.5E-27 T 12-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 HW35_11790 5f74994ca5beb90d2339135b19c22035 99 Gene3D G3DSA:2.102.10.10 1 99 1.0E-23 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 HW35_11790 5f74994ca5beb90d2339135b19c22035 99 Pfam PF13806 Rieske-like [2Fe-2S] domain 2 97 9.8E-18 T 12-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 HW35_11790 5f74994ca5beb90d2339135b19c22035 99 SUPERFAMILY SSF50022 2 98 2.62E-26 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 HW35_10965 cd33cb23f50552c363d857b5f20719a7 240 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 44 227 4.7E-50 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HW35_10965 cd33cb23f50552c363d857b5f20719a7 240 SUPERFAMILY SSF53187 42 231 7.53E-53 T 12-10-2018 HW35_10965 cd33cb23f50552c363d857b5f20719a7 240 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 42 229 7.4E-85 T 12-10-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD MetaCyc: PWY-7883 HW35_10965 cd33cb23f50552c363d857b5f20719a7 240 Gene3D G3DSA:3.40.630.40 37 239 4.5E-57 T 12-10-2018 HW35_10965 cd33cb23f50552c363d857b5f20719a7 240 SMART SM00646 116 227 1.1E-35 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HW35_10320 58ce2f18f4bf910036926d897410e02a 130 Pfam PF04977 Septum formation initiator 52 122 1.9E-17 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC HW35_12820 d4a1072805e3c0b19d2da302f7cbed18 416 PRINTS PR00723 Subtilisin serine protease family (S8) signature 353 369 2.2E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_12820 d4a1072805e3c0b19d2da302f7cbed18 416 PRINTS PR00723 Subtilisin serine protease family (S8) signature 131 150 2.2E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_12820 d4a1072805e3c0b19d2da302f7cbed18 416 PRINTS PR00723 Subtilisin serine protease family (S8) signature 173 186 2.2E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related HW35_12820 d4a1072805e3c0b19d2da302f7cbed18 416 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 177 187 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site HW35_12820 d4a1072805e3c0b19d2da302f7cbed18 416 Pfam PF00082 Subtilase family 131 411 1.4E-49 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HW35_12820 d4a1072805e3c0b19d2da302f7cbed18 416 Gene3D G3DSA:3.40.50.200 107 416 2.0E-103 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 HW35_12820 d4a1072805e3c0b19d2da302f7cbed18 416 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 136 147 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site HW35_12820 d4a1072805e3c0b19d2da302f7cbed18 416 SUPERFAMILY SSF52743 112 413 6.02E-84 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 HW35_12820 d4a1072805e3c0b19d2da302f7cbed18 416 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 354 364 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site HW35_10695 d54cb667f711ab61774d71dee7b1efb9 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 4.1E-67 T 12-10-2018 IPR023798 Ribosomal protein S7 domain HW35_10695 d54cb667f711ab61774d71dee7b1efb9 156 PIRSF PIRSF002122 5 156 1.5E-58 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 HW35_10695 d54cb667f711ab61774d71dee7b1efb9 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.5E-70 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 HW35_10695 d54cb667f711ab61774d71dee7b1efb9 156 Gene3D G3DSA:1.10.455.10 2 156 6.7E-64 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily HW35_10695 d54cb667f711ab61774d71dee7b1efb9 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10695 d54cb667f711ab61774d71dee7b1efb9 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.047 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 HW35_10695 d54cb667f711ab61774d71dee7b1efb9 156 SUPERFAMILY SSF47973 1 149 1.19E-62 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily HW35_02505 a4e20d59437040d71415a7f9943ef337 150 Gene3D G3DSA:2.60.40.420 32 150 5.1E-15 T 12-10-2018 IPR008972 Cupredoxin HW35_02505 a4e20d59437040d71415a7f9943ef337 150 Pfam PF13473 Cupredoxin-like domain 48 136 1.2E-8 T 12-10-2018 IPR028096 EfeO-type cupredoxin-like domain HW35_02505 a4e20d59437040d71415a7f9943ef337 150 SUPERFAMILY SSF49503 69 143 2.48E-12 T 12-10-2018 IPR008972 Cupredoxin HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 433 34.916 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 376 1.4E-18 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 SUPERFAMILY SSF51984 4 88 1.84E-19 T 12-10-2018 HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 SUPERFAMILY SSF53623 87 293 3.01E-56 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 Gene3D G3DSA:3.90.190.20 292 432 4.8E-42 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 SUPERFAMILY SSF53244 294 429 2.01E-37 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 Gene3D G3DSA:3.40.1190.10 91 291 2.0E-49 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 425 2.3E-133 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 Gene3D G3DSA:3.40.50.720 3 89 6.6E-21 T 12-10-2018 HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 Pfam PF08245 Mur ligase middle domain 106 275 1.4E-24 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 HW35_05945 e30e14136e897bf64c01a6a33ddf59c3 433 Pfam PF01225 Mur ligase family, catalytic domain 4 101 1.6E-22 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HW35_08110 40fb7c1cb4e07bf5954671f8a9455ad0 271 Pfam PF02535 ZIP Zinc transporter 128 265 2.1E-22 T 12-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 HW35_08110 40fb7c1cb4e07bf5954671f8a9455ad0 271 Hamap MF_00548 Zinc transporter ZupT [zupT]. 5 271 35.444 T 12-10-2018 IPR023498 Zinc transporter ZupT HW35_01375 cc6f7a2bb5d8ede028724c6df18b2397 241 Pfam PF04055 Radical SAM superfamily 28 124 9.0E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_01375 cc6f7a2bb5d8ede028724c6df18b2397 241 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 238 35.331 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 HW35_01375 cc6f7a2bb5d8ede028724c6df18b2397 241 Pfam PF13394 4Fe-4S single cluster domain 26 100 4.2E-10 T 12-10-2018 HW35_01375 cc6f7a2bb5d8ede028724c6df18b2397 241 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 3 241 7.8E-117 T 12-10-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 HW35_01375 cc6f7a2bb5d8ede028724c6df18b2397 241 PIRSF PIRSF000370 2 241 6.8E-53 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 HW35_01375 cc6f7a2bb5d8ede028724c6df18b2397 241 SUPERFAMILY SSF102114 26 165 1.31E-12 T 12-10-2018 HW35_01375 cc6f7a2bb5d8ede028724c6df18b2397 241 Gene3D G3DSA:3.20.20.70 4 234 6.1E-30 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 285 311 8.1E-4 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 352 5.5E-6 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 429 3.3E-7 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 Pfam PF00483 Nucleotidyl transferase 6 221 9.2E-26 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 Gene3D G3DSA:3.90.550.10 1 252 3.0E-81 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 452 5.7E-190 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 SUPERFAMILY SSF51161 249 448 3.21E-48 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 Gene3D G3DSA:2.160.10.10 253 439 1.0E-53 T 12-10-2018 HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 SUPERFAMILY SSF53448 4 307 1.37E-66 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_10260 63d6f8573320f11bc36294f893b2e6c1 457 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 42.323 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 HW35_06360 5fa01eb349d1eb7c42788949b3acf3ec 190 SUPERFAMILY SSF53056 5 184 2.09E-43 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 HW35_06360 5fa01eb349d1eb7c42788949b3acf3ec 190 Pfam PF00484 Carbonic anhydrase 37 181 1.1E-17 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HW35_06360 5fa01eb349d1eb7c42788949b3acf3ec 190 SMART SM00947 29 185 6.4E-38 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HW35_06360 5fa01eb349d1eb7c42788949b3acf3ec 190 Gene3D G3DSA:3.40.1050.10 6 186 3.4E-47 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 HW35_11225 9cdd3b13f2e4867f26d90a9c692bce85 271 PIRSF PIRSF028177 4 271 7.0E-75 T 12-10-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 HW35_11225 9cdd3b13f2e4867f26d90a9c692bce85 271 Pfam PF04072 Leucine carboxyl methyltransferase 56 175 1.7E-18 T 12-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 HW35_11225 9cdd3b13f2e4867f26d90a9c692bce85 271 Gene3D G3DSA:3.40.50.150 10 238 6.5E-36 T 12-10-2018 HW35_11225 9cdd3b13f2e4867f26d90a9c692bce85 271 SUPERFAMILY SSF53335 16 229 1.61E-47 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_11205 8de353eb044d34846b22b54ef044bd24 88 Pfam PF13143 Protein of unknown function (DUF3986) 5 84 9.4E-16 T 12-10-2018 IPR025047 Protein of unknown function DUF3986 HW35_13800 d2d50883c03833f50b46f0baa667a3fb 139 Hamap MF_01624 Arsenate reductase [arsC]. 1 137 46.306 T 12-10-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 HW35_13800 d2d50883c03833f50b46f0baa667a3fb 139 SUPERFAMILY SSF52788 4 136 4.19E-45 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily HW35_13800 d2d50883c03833f50b46f0baa667a3fb 139 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 134 1.9E-22 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I HW35_13800 d2d50883c03833f50b46f0baa667a3fb 139 Gene3D G3DSA:3.40.50.2300 1 139 1.9E-58 T 12-10-2018 HW35_13800 d2d50883c03833f50b46f0baa667a3fb 139 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 6 134 2.4E-72 T 12-10-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 HW35_13800 d2d50883c03833f50b46f0baa667a3fb 139 SMART SM00226 4 137 3.9E-62 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I HW35_14900 642e2689472a4593f307859983b00300 288 SUPERFAMILY SSF54534 120 228 1.18E-27 T 12-10-2018 HW35_14900 642e2689472a4593f307859983b00300 288 Gene3D G3DSA:3.10.50.40 136 230 1.9E-31 T 12-10-2018 HW35_14900 642e2689472a4593f307859983b00300 288 Hamap MF_01145 Foldase protein PrsA [prsA]. 2 284 21.733 T 12-10-2018 IPR023059 Foldase protein PrsA GO:0003755 HW35_14900 642e2689472a4593f307859983b00300 288 Gene3D G3DSA:1.10.4030.30 44 239 1.9E-31 T 12-10-2018 HW35_14900 642e2689472a4593f307859983b00300 288 SUPERFAMILY SSF109998 34 163 5.89E-18 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily HW35_14900 642e2689472a4593f307859983b00300 288 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 164 185 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 HW35_14900 642e2689472a4593f307859983b00300 288 Pfam PF13616 PPIC-type PPIASE domain 136 230 7.5E-24 T 12-10-2018 HW35_09455 b5975b3a2f66366e1112a382e4a30974 223 Gene3D G3DSA:3.40.50.10320 1 218 1.0E-55 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 HW35_09455 b5975b3a2f66366e1112a382e4a30974 223 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 5 221 1.2E-112 T 12-10-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 HW35_09455 b5975b3a2f66366e1112a382e4a30974 223 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 137 2.9E-31 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 HW35_09455 b5975b3a2f66366e1112a382e4a30974 223 SUPERFAMILY SSF102588 4 190 7.19E-54 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 HW35_13325 5a37236cfb1a44c36f3edca8cbcd8d67 111 SUPERFAMILY SSF46955 14 96 5.49E-16 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily HW35_13325 5a37236cfb1a44c36f3edca8cbcd8d67 111 SMART SM00422 13 82 3.9E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_13325 5a37236cfb1a44c36f3edca8cbcd8d67 111 Gene3D G3DSA:1.10.1660.10 5 88 3.9E-21 T 12-10-2018 HW35_13325 5a37236cfb1a44c36f3edca8cbcd8d67 111 Pfam PF13411 MerR HTH family regulatory protein 14 78 1.7E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_00475 4d44cbf5dd0e5971422dff3f982fb0a9 536 PRINTS PR01009 Flagellar M-ring protein signature 355 379 2.6E-19 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HW35_00475 4d44cbf5dd0e5971422dff3f982fb0a9 536 PRINTS PR01009 Flagellar M-ring protein signature 160 174 2.6E-19 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HW35_00475 4d44cbf5dd0e5971422dff3f982fb0a9 536 PRINTS PR01009 Flagellar M-ring protein signature 278 296 2.6E-19 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HW35_00475 4d44cbf5dd0e5971422dff3f982fb0a9 536 PRINTS PR01009 Flagellar M-ring protein signature 128 146 2.6E-19 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HW35_00475 4d44cbf5dd0e5971422dff3f982fb0a9 536 PRINTS PR01009 Flagellar M-ring protein signature 205 223 2.6E-19 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HW35_00475 4d44cbf5dd0e5971422dff3f982fb0a9 536 Pfam PF08345 Flagellar M-ring protein C-terminal 265 407 2.0E-20 T 12-10-2018 IPR013556 Flagellar M-ring C-terminal HW35_00475 4d44cbf5dd0e5971422dff3f982fb0a9 536 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 9 534 8.9E-88 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HW35_00475 4d44cbf5dd0e5971422dff3f982fb0a9 536 Pfam PF01514 Secretory protein of YscJ/FliF family 36 228 8.6E-54 T 12-10-2018 IPR006182 Secretory protein YscJ/FliF HW35_00475 4d44cbf5dd0e5971422dff3f982fb0a9 536 Gene3D G3DSA:3.30.300.30 140 229 3.4E-9 T 12-10-2018 HW35_00475 4d44cbf5dd0e5971422dff3f982fb0a9 536 PIRSF PIRSF004862 6 536 3.2E-97 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HW35_16255 d5753797417eda0ec637e59116b439c7 70 Pfam PF00364 Biotin-requiring enzyme 2 69 2.9E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment HW35_16255 d5753797417eda0ec637e59116b439c7 70 Gene3D G3DSA:2.40.50.100 3 70 4.8E-24 T 12-10-2018 HW35_16255 d5753797417eda0ec637e59116b439c7 70 SUPERFAMILY SSF51230 3 69 4.19E-20 T 12-10-2018 IPR011053 Single hybrid motif HW35_05295 cfd85fd9d25693caa97c87385b74216e 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 62 3.7E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_05295 cfd85fd9d25693caa97c87385b74216e 200 SUPERFAMILY SSF46689 5 86 2.44E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_05295 cfd85fd9d25693caa97c87385b74216e 200 Gene3D G3DSA:1.10.357.10 2 189 2.5E-22 T 12-10-2018 HW35_07675 8e3ac00160cb639811448f34c4185dea 181 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 106 140 1.0E-10 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_07675 8e3ac00160cb639811448f34c4185dea 181 Gene3D G3DSA:2.160.10.10 29 170 1.2E-28 T 12-10-2018 HW35_07675 8e3ac00160cb639811448f34c4185dea 181 SUPERFAMILY SSF51161 10 158 1.94E-34 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily HW35_06145 07abb53ca904e9738e52a51d3f095fd1 361 Pfam PF10776 Protein of unknown function (DUF2600) 16 344 1.5E-148 T 12-10-2018 IPR019712 Protein of unknown function DUF2600 HW35_00410 adb86dfd5388ef083c2d7acc2b929382 91 Pfam PF04316 Anti-sigma-28 factor, FlgM 34 84 1.4E-17 T 12-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal HW35_00410 adb86dfd5388ef083c2d7acc2b929382 91 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 24 86 1.1E-17 T 12-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 HW35_00410 adb86dfd5388ef083c2d7acc2b929382 91 SUPERFAMILY SSF101498 1 86 1.12E-17 T 12-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily HW35_16605 0bbe07734e7a627b76b0f066ad091d8a 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 1.3E-36 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 HW35_05445 bf3fe98bf6bff1e86bfc420b28eb3a5f 104 Pfam PF00085 Thioredoxin 3 103 1.6E-33 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 HW35_05445 bf3fe98bf6bff1e86bfc420b28eb3a5f 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 103 2.1E-40 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HW35_05445 bf3fe98bf6bff1e86bfc420b28eb3a5f 104 PRINTS PR00421 Thioredoxin family signature 68 79 1.3E-9 T 12-10-2018 HW35_05445 bf3fe98bf6bff1e86bfc420b28eb3a5f 104 PRINTS PR00421 Thioredoxin family signature 20 28 1.3E-9 T 12-10-2018 HW35_05445 bf3fe98bf6bff1e86bfc420b28eb3a5f 104 PRINTS PR00421 Thioredoxin family signature 28 37 1.3E-9 T 12-10-2018 HW35_05445 bf3fe98bf6bff1e86bfc420b28eb3a5f 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 HW35_05445 bf3fe98bf6bff1e86bfc420b28eb3a5f 104 Gene3D G3DSA:3.40.30.10 1 104 3.7E-37 T 12-10-2018 HW35_05445 bf3fe98bf6bff1e86bfc420b28eb3a5f 104 PIRSF PIRSF000077 1 104 2.0E-43 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HW35_05445 bf3fe98bf6bff1e86bfc420b28eb3a5f 104 SUPERFAMILY SSF52833 3 104 1.16E-39 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_05530 fe799dc608d334899e8e472a9425fada 345 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 49.492 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 HW35_05530 fe799dc608d334899e8e472a9425fada 345 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 342 3.5E-113 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 HW35_05530 fe799dc608d334899e8e472a9425fada 345 Gene3D G3DSA:3.30.930.10 8 344 2.0E-126 T 12-10-2018 HW35_05530 fe799dc608d334899e8e472a9425fada 345 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 88 6.8E-26 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HW35_05530 fe799dc608d334899e8e472a9425fada 345 SUPERFAMILY SSF46589 14 100 2.04E-22 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 HW35_05530 fe799dc608d334899e8e472a9425fada 345 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 3.4E-110 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 HW35_05530 fe799dc608d334899e8e472a9425fada 345 SUPERFAMILY SSF55681 93 342 1.35E-84 T 12-10-2018 HW35_11775 23cb0604f761d2939ad2f261740e393a 388 Pfam PF07537 CamS sex pheromone cAM373 precursor 57 380 1.1E-118 T 12-10-2018 IPR011426 CamS sex pheromone cAM373 HW35_11775 23cb0604f761d2939ad2f261740e393a 388 PIRSF PIRSF012509 1 388 1.6E-144 T 12-10-2018 IPR011426 CamS sex pheromone cAM373 HW35_11775 23cb0604f761d2939ad2f261740e393a 388 Gene3D G3DSA:3.10.570.10 54 388 2.0E-131 T 12-10-2018 HW35_13815 367a24356abcb8501e0e67c71ad14e85 256 Pfam PF13847 Methyltransferase domain 82 195 2.6E-14 T 12-10-2018 IPR025714 Methyltransferase domain HW35_13815 367a24356abcb8501e0e67c71ad14e85 256 Gene3D G3DSA:3.40.50.150 58 224 6.7E-26 T 12-10-2018 HW35_13815 367a24356abcb8501e0e67c71ad14e85 256 SUPERFAMILY SSF53335 69 216 4.26E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_09740 0b28ab645b5f4f375350b747b58b21ba 189 Pfam PF02632 BioY family 29 172 1.7E-34 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 HW35_09740 0b28ab645b5f4f375350b747b58b21ba 189 PIRSF PIRSF016661 1 176 1.2E-42 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 HW35_09740 0b28ab645b5f4f375350b747b58b21ba 189 Gene3D G3DSA:1.10.1760.20 1 180 4.9E-50 T 12-10-2018 HW35_00390 f10369279b2e0b840f652844ecad5e28 115 SUPERFAMILY SSF160214 12 115 4.05E-27 T 12-10-2018 IPR035924 FlaG-like superfamily HW35_00390 f10369279b2e0b840f652844ecad5e28 115 Gene3D G3DSA:3.30.160.170 6 111 6.0E-31 T 12-10-2018 IPR035924 FlaG-like superfamily HW35_00390 f10369279b2e0b840f652844ecad5e28 115 Pfam PF03646 FlaG protein 28 113 3.0E-26 T 12-10-2018 IPR005186 FlaG protein HW35_04545 d47229135bd2afb318a83bafd002efba 210 Gene3D G3DSA:2.30.22.10 154 210 2.5E-23 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 HW35_04545 d47229135bd2afb318a83bafd002efba 210 Hamap MF_01151 Protein GrpE [grpE]. 13 210 21.495 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HW35_04545 d47229135bd2afb318a83bafd002efba 210 SUPERFAMILY SSF51064 155 210 6.67E-18 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 HW35_04545 d47229135bd2afb318a83bafd002efba 210 Pfam PF01025 GrpE 48 210 3.1E-56 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HW35_04545 d47229135bd2afb318a83bafd002efba 210 SUPERFAMILY SSF58014 59 154 1.44E-27 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 HW35_04545 d47229135bd2afb318a83bafd002efba 210 Gene3D G3DSA:3.90.20.20 34 152 5.9E-28 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 HW35_04545 d47229135bd2afb318a83bafd002efba 210 ProSitePatterns PS01071 grpE protein signature. 165 208 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HW35_04545 d47229135bd2afb318a83bafd002efba 210 PRINTS PR00773 GrpE protein signature 108 123 4.7E-29 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HW35_04545 d47229135bd2afb318a83bafd002efba 210 PRINTS PR00773 GrpE protein signature 189 208 4.7E-29 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HW35_04545 d47229135bd2afb318a83bafd002efba 210 PRINTS PR00773 GrpE protein signature 80 96 4.7E-29 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HW35_04545 d47229135bd2afb318a83bafd002efba 210 PRINTS PR00773 GrpE protein signature 162 177 4.7E-29 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HW35_15335 aea273bf292bd9e308c86444715afae8 131 SUPERFAMILY SSF52833 1 129 8.99E-41 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_15335 aea273bf292bd9e308c86444715afae8 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 3.7E-38 T 12-10-2018 IPR006504 Transcriptional regulator Spx/MgsR HW35_15335 aea273bf292bd9e308c86444715afae8 131 Gene3D G3DSA:3.40.30.10 1 131 1.3E-48 T 12-10-2018 HW35_15335 aea273bf292bd9e308c86444715afae8 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 38.192 T 12-10-2018 IPR023731 Regulatory protein Spx GO:0045892 HW35_15335 aea273bf292bd9e308c86444715afae8 131 Pfam PF03960 ArsC family 5 113 1.0E-23 T 12-10-2018 IPR006660 Arsenate reductase-like HW35_16205 209d17250e42114773f53d7ced1bab63 408 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 9 396 8.9E-124 T 12-10-2018 IPR014226 Sporulation integral membrane protein YlbJ HW35_16205 209d17250e42114773f53d7ced1bab63 408 Pfam PF07670 Nucleoside recognition 219 302 9.7E-6 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HW35_16205 209d17250e42114773f53d7ced1bab63 408 Pfam PF07670 Nucleoside recognition 42 140 9.5E-6 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HW35_15025 51de1eeec1e88ca76d02138ae67d9bc9 423 Gene3D G3DSA:3.30.2010.10 204 285 3.7E-24 T 12-10-2018 HW35_15025 51de1eeec1e88ca76d02138ae67d9bc9 423 Pfam PF01435 Peptidase family M48 208 416 1.7E-37 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HW35_15025 51de1eeec1e88ca76d02138ae67d9bc9 423 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 51 204 6.9E-21 T 12-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 HW35_16180 8c4bd3666277664d413591334693f114 290 Gene3D G3DSA:3.30.420.10 127 277 6.2E-11 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_16180 8c4bd3666277664d413591334693f114 290 Pfam PF00665 Integrase core domain 132 243 3.3E-23 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_16180 8c4bd3666277664d413591334693f114 290 SUPERFAMILY SSF53098 124 283 2.43E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_16180 8c4bd3666277664d413591334693f114 290 Pfam PF13276 HTH-like domain 53 108 1.5E-19 T 12-10-2018 IPR025948 HTH-like domain HW35_07865 2d5038170a1b394af65353462f0f432f 186 SUPERFAMILY SSF48295 36 118 4.92E-15 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HW35_07865 2d5038170a1b394af65353462f0f432f 186 Pfam PF13518 Helix-turn-helix domain 66 118 2.8E-6 T 12-10-2018 HW35_14820 5a002ffb13c394902d8332dcf1455024 69 ProDom PD056348 YHEE BH1143 1 69 1.0E-16 T 12-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 HW35_14820 5a002ffb13c394902d8332dcf1455024 69 PIRSF PIRSF037692 1 69 2.2E-30 T 12-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 HW35_14820 5a002ffb13c394902d8332dcf1455024 69 Pfam PF17277 Family of unknown function (DUF5342) 1 69 7.7E-34 T 12-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 HW35_08920 c6e78ff963a44462cb34512ab73c3c4d 215 SUPERFAMILY SSF161098 12 197 1.7E-44 T 12-10-2018 IPR035906 MetI-like superfamily HW35_08920 c6e78ff963a44462cb34512ab73c3c4d 215 Gene3D G3DSA:1.10.3720.10 2 213 1.5E-56 T 12-10-2018 IPR035906 MetI-like superfamily HW35_08920 c6e78ff963a44462cb34512ab73c3c4d 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 211 2.3E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_08920 c6e78ff963a44462cb34512ab73c3c4d 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 106 1.6E-26 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 164 338 3.5E-10 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 Gene3D G3DSA:3.40.50.800 365 459 2.0E-30 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 4 242 1.1E-90 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 2 459 52.08 T 12-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 SUPERFAMILY SSF55681 4 372 1.59E-128 T 12-10-2018 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 Pfam PF03129 Anticodon binding domain 369 457 1.3E-23 T 12-10-2018 IPR004154 Anticodon-binding HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 SUPERFAMILY SSF52954 356 458 1.33E-33 T 12-10-2018 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 147 159 5.8E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 324 336 5.8E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 217 227 5.8E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 200 217 5.8E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 24 38 5.8E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 168 185 5.8E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_04450 44259f0c4e9303b4c8a75c78967f7bfd 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 404 423 5.8E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HW35_03360 b9c5e77f9dc3958711070ea267853156 269 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 22 226 9.3E-67 T 12-10-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 HW35_03760 b93deb08be4f6360b373853a5257af6a 79 Pfam PF13025 Protein of unknown function (DUF3886) 10 77 2.2E-25 T 12-10-2018 IPR024980 Protein of unknown function DUF3886 HW35_03040 8861155f2cc435c9e54d071b2615572e 77 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 10 76 1.9E-27 T 12-10-2018 IPR018720 Domain of unknown function DUF2249 HW35_12630 90e08eac05ed8ba522fd54fcb57faaae 144 Gene3D G3DSA:3.10.580.10 1 142 2.1E-40 T 12-10-2018 HW35_12630 90e08eac05ed8ba522fd54fcb57faaae 144 Pfam PF00571 CBS domain 69 120 7.9E-11 T 12-10-2018 IPR000644 CBS domain HW35_12630 90e08eac05ed8ba522fd54fcb57faaae 144 Pfam PF00571 CBS domain 5 54 2.5E-16 T 12-10-2018 IPR000644 CBS domain HW35_12630 90e08eac05ed8ba522fd54fcb57faaae 144 SMART SM00116 77 124 2.3E-8 T 12-10-2018 IPR000644 CBS domain HW35_12630 90e08eac05ed8ba522fd54fcb57faaae 144 SMART SM00116 11 59 1.3E-13 T 12-10-2018 IPR000644 CBS domain HW35_12630 90e08eac05ed8ba522fd54fcb57faaae 144 SUPERFAMILY SSF54631 4 119 1.12E-35 T 12-10-2018 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 SUPERFAMILY SSF55347 182 486 5.56E-113 T 12-10-2018 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 6 487 85.79 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 190 485 1.7E-114 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 Gene3D G3DSA:3.30.360.10 176 487 1.4E-123 T 12-10-2018 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 7 486 3.3E-196 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 177 183 - T 12-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 Gene3D G3DSA:3.40.50.720 3 175 9.4E-59 T 12-10-2018 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 PIRSF PIRSF000110 1 489 4.2E-187 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 SUPERFAMILY SSF51735 7 190 4.33E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 219 236 6.5E-48 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 143 156 6.5E-48 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 328 354 6.5E-48 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 167 195 6.5E-48 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 237 253 6.5E-48 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_03830 9f60d5bf0ca02557b62a83ab5172d4f8 497 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 10 187 6.5E-60 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HW35_06900 026f584daaecbd7729f5bde7c83546f9 202 SUPERFAMILY SSF50685 107 148 2.72E-7 T 12-10-2018 IPR036908 RlpA-like domain superfamily HW35_06900 026f584daaecbd7729f5bde7c83546f9 202 Pfam PF06725 3D domain 107 168 8.3E-19 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 HW35_06935 45408f000b8cd182ba328fe9f3cc7cb8 121 Gene3D G3DSA:2.60.300.12 5 113 3.9E-37 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 HW35_06935 45408f000b8cd182ba328fe9f3cc7cb8 121 Pfam PF01521 Iron-sulphur cluster biosynthesis 6 106 1.4E-20 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 HW35_06935 45408f000b8cd182ba328fe9f3cc7cb8 121 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 92 109 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 HW35_06935 45408f000b8cd182ba328fe9f3cc7cb8 121 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 6 110 4.7E-38 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 HW35_06935 45408f000b8cd182ba328fe9f3cc7cb8 121 SUPERFAMILY SSF89360 4 97 2.16E-30 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 HW35_07645 d18f4f5f1535f0c3528d19c3c5ac6603 208 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 200 37.468 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 HW35_07645 d18f4f5f1535f0c3528d19c3c5ac6603 208 SUPERFAMILY SSF52317 2 200 2.5E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_07645 d18f4f5f1535f0c3528d19c3c5ac6603 208 Gene3D G3DSA:3.40.50.880 1 207 3.5E-73 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_07645 d18f4f5f1535f0c3528d19c3c5ac6603 208 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 200 5.9E-71 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 HW35_07645 d18f4f5f1535f0c3528d19c3c5ac6603 208 PIRSF PIRSF000495 1 203 7.9E-74 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 HW35_07645 d18f4f5f1535f0c3528d19c3c5ac6603 208 Pfam PF00117 Glutamine amidotransferase class-I 4 198 7.0E-25 T 12-10-2018 IPR017926 Glutamine amidotransferase HW35_14225 1a34bfb5b05e0bf8e867c3ec0bc081fb 51 Pfam PF08176 Small acid-soluble spore protein K family 1 47 9.7E-30 T 12-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 HW35_14225 1a34bfb5b05e0bf8e867c3ec0bc081fb 51 Hamap MF_01504 Small, acid-soluble spore protein K [sspK]. 1 49 18.59 T 12-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 HW35_14225 1a34bfb5b05e0bf8e867c3ec0bc081fb 51 TIGRFAM TIGR03091 SASP_sspK: small, acid-soluble spore protein K 16 47 6.3E-23 T 12-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 HW35_03725 72b460c84cb642d1a607e858b39d3ab9 213 PIRSF PIRSF038973 1 213 6.3E-71 T 12-10-2018 IPR014196 Stage II sporulation protein M HW35_03725 72b460c84cb642d1a607e858b39d3ab9 213 Pfam PF01944 Stage II sporulation protein M 25 202 1.4E-25 T 12-10-2018 IPR002798 Stage II sporulation protein M-like HW35_03725 72b460c84cb642d1a607e858b39d3ab9 213 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 9 206 1.1E-70 T 12-10-2018 IPR014196 Stage II sporulation protein M HW35_04710 19d205798d322754279d08083f996088 307 Gene3D G3DSA:3.40.50.1100 45 146 3.9E-117 T 12-10-2018 HW35_04710 19d205798d322754279d08083f996088 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 292 1.4E-62 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HW35_04710 19d205798d322754279d08083f996088 307 Gene3D G3DSA:3.40.50.1100 10 299 3.9E-117 T 12-10-2018 HW35_04710 19d205798d322754279d08083f996088 307 SUPERFAMILY SSF53686 1 302 2.36E-93 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HW35_04710 19d205798d322754279d08083f996088 307 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 303 1.6E-104 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 HW35_04710 19d205798d322754279d08083f996088 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 HW35_16630 b8dab793a1edfe2f390065916422f23a 198 SUPERFAMILY SSF54637 74 182 6.13E-25 T 12-10-2018 IPR029069 HotDog domain superfamily HW35_16630 b8dab793a1edfe2f390065916422f23a 198 Pfam PF08220 DeoR-like helix-turn-helix domain 8 50 3.2E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HW35_16630 b8dab793a1edfe2f390065916422f23a 198 PIRSF PIRSF037733 1 191 3.4E-85 T 12-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 HW35_16630 b8dab793a1edfe2f390065916422f23a 198 SUPERFAMILY SSF46785 5 52 7.14E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_16630 b8dab793a1edfe2f390065916422f23a 198 Hamap MF_01814 Transcription factor FapR [fapR]. 1 188 38.847 T 12-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 HW35_16630 b8dab793a1edfe2f390065916422f23a 198 Gene3D G3DSA:3.10.129.10 68 188 4.8E-39 T 12-10-2018 HW35_16630 b8dab793a1edfe2f390065916422f23a 198 Gene3D G3DSA:1.10.10.10 1 60 1.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_12055 a64a936d65ea65dd5436e1d2cc0a13fa 120 Gene3D G3DSA:3.10.180.10 1 120 1.7E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_12055 a64a936d65ea65dd5436e1d2cc0a13fa 120 SUPERFAMILY SSF54593 1 118 2.69E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_12055 a64a936d65ea65dd5436e1d2cc0a13fa 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 116 7.5E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HW35_16155 ae49564693df096b669331160f77a046 79 Pfam PF14003 YlbE-like protein 14 73 8.6E-26 T 12-10-2018 IPR025613 YlbE-like protein HW35_08695 4d70c8e90deb72b4609ef865539ea94c 72 Pfam PF07872 Protein of unknown function (DUF1659) 7 50 7.5E-17 T 12-10-2018 IPR012454 Protein of unknown function DUF1659 HW35_11930 cec9f7731b3dd6a24885ee618dda733b 313 Gene3D G3DSA:1.10.357.140 39 193 2.1E-14 T 12-10-2018 HW35_11930 cec9f7731b3dd6a24885ee618dda733b 313 Pfam PF01040 UbiA prenyltransferase family 44 293 1.2E-49 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 HW35_11930 cec9f7731b3dd6a24885ee618dda733b 313 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 32 306 3.9E-77 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 HW35_11930 cec9f7731b3dd6a24885ee618dda733b 313 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 86 108 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site HW35_11930 cec9f7731b3dd6a24885ee618dda733b 313 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 26 309 16.069 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 HW35_09290 1864e5f548bf9e42de7fb9fa0477af96 703 SUPERFAMILY SSF46548 251 399 9.59E-19 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HW35_09290 1864e5f548bf9e42de7fb9fa0477af96 703 SUPERFAMILY SSF103501 8 238 2.88E-16 T 12-10-2018 IPR036197 NarG-like superfamily HW35_09290 1864e5f548bf9e42de7fb9fa0477af96 703 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 371 382 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_09290 1864e5f548bf9e42de7fb9fa0477af96 703 Pfam PF13183 4Fe-4S dicluster domain 274 383 2.8E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HW35_09290 1864e5f548bf9e42de7fb9fa0477af96 703 Pfam PF02754 Cysteine-rich domain 459 537 3.0E-7 T 12-10-2018 IPR004017 Cysteine-rich domain HW35_09290 1864e5f548bf9e42de7fb9fa0477af96 703 Pfam PF02754 Cysteine-rich domain 581 668 2.0E-18 T 12-10-2018 IPR004017 Cysteine-rich domain HW35_09625 e44b3ff421daf09f6900dec831e4601f 343 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 7.9E-29 T 12-10-2018 HW35_09625 e44b3ff421daf09f6900dec831e4601f 343 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 7.9E-29 T 12-10-2018 HW35_09625 e44b3ff421daf09f6900dec831e4601f 343 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 7.9E-29 T 12-10-2018 HW35_09625 e44b3ff421daf09f6900dec831e4601f 343 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 7.9E-29 T 12-10-2018 HW35_09625 e44b3ff421daf09f6900dec831e4601f 343 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 262 5.8E-59 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HW35_09625 e44b3ff421daf09f6900dec831e4601f 343 Gene3D G3DSA:3.40.50.720 4 316 2.1E-100 T 12-10-2018 HW35_09625 e44b3ff421daf09f6900dec831e4601f 343 SUPERFAMILY SSF51735 1 331 6.14E-93 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_09625 e44b3ff421daf09f6900dec831e4601f 343 Gene3D G3DSA:3.90.25.10 180 328 2.1E-100 T 12-10-2018 HW35_16105 73fc6f3d4389daa46936e92c1ccf6e70 209 Gene3D G3DSA:1.20.120.80 21 208 8.8E-52 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16105 73fc6f3d4389daa46936e92c1ccf6e70 209 Pfam PF00510 Cytochrome c oxidase subunit III 28 206 1.5E-17 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16105 73fc6f3d4389daa46936e92c1ccf6e70 209 SUPERFAMILY SSF81452 18 206 2.88E-53 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16940 eb8a515b8c31b8fd4f88a7f05ddaf152 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 330 1.4E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 HW35_00125 93dca887b25138f3b35b382e012af2da 203 Gene3D G3DSA:3.40.50.1240 5 187 2.9E-34 T 12-10-2018 IPR029033 Histidine phosphatase superfamily HW35_00125 93dca887b25138f3b35b382e012af2da 203 SUPERFAMILY SSF53254 7 179 3.85E-32 T 12-10-2018 IPR029033 Histidine phosphatase superfamily HW35_00125 93dca887b25138f3b35b382e012af2da 203 SMART SM00855 6 152 1.3E-9 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HW35_00125 93dca887b25138f3b35b382e012af2da 203 PIRSF PIRSF000709 7 185 1.1E-5 T 12-10-2018 HW35_00125 93dca887b25138f3b35b382e012af2da 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 168 2.8E-24 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HW35_01560 6d512573cc72eeabacd33f6f5c8c12eb 110 Pfam PF11417 Loader and inhibitor of phage G40P 1 62 2.5E-7 T 12-10-2018 IPR024424 Replicative helicase inhibitor G39P, N-terminal HW35_01560 6d512573cc72eeabacd33f6f5c8c12eb 110 Gene3D G3DSA:1.10.8.200 2 63 1.1E-11 T 12-10-2018 HW35_01560 6d512573cc72eeabacd33f6f5c8c12eb 110 SUPERFAMILY SSF89064 3 62 1.05E-5 T 12-10-2018 IPR036173 G39, N-terminal domain superfamily HW35_09105 c99af8049dcf3d1bf861caabe9d60ee5 175 Pfam PF00430 ATP synthase B/B' CF(0) 22 152 4.4E-40 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HW35_09105 c99af8049dcf3d1bf861caabe9d60ee5 175 SUPERFAMILY SSF81573 78 136 1.57E-10 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily HW35_09105 c99af8049dcf3d1bf861caabe9d60ee5 175 Hamap MF_01398 ATP synthase subunit b [atpF]. 16 153 14.012 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HW35_09105 c99af8049dcf3d1bf861caabe9d60ee5 175 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 25 170 2.2E-45 T 12-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 HW35_15285 198955305b3a37dcbeb97cfd97ccc819 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 301 3.0E-30 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_15285 198955305b3a37dcbeb97cfd97ccc819 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 63 4.1E-11 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HW35_15285 198955305b3a37dcbeb97cfd97ccc819 303 Gene3D G3DSA:1.10.3720.10 84 301 4.3E-22 T 12-10-2018 IPR035906 MetI-like superfamily HW35_15285 198955305b3a37dcbeb97cfd97ccc819 303 SUPERFAMILY SSF161098 91 282 2.49E-25 T 12-10-2018 IPR035906 MetI-like superfamily HW35_01930 5dc2f560b199960844cbc414d1198b9a 160 Gene3D G3DSA:2.60.40.2360 36 158 9.2E-17 T 12-10-2018 IPR038144 Intracellular proteinase inhibitor HW35_01930 5dc2f560b199960844cbc414d1198b9a 160 Pfam PF12690 Intracellular proteinase inhibitor 62 136 1.2E-10 T 12-10-2018 IPR020481 Intracellular proteinase inhibitor BsuPI HW35_04820 c2961a6c0ef57622977b22f50d8a0712 139 SUPERFAMILY SSF46785 2 127 3.13E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_04820 c2961a6c0ef57622977b22f50d8a0712 139 Gene3D G3DSA:1.10.10.10 1 139 5.4E-52 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_04820 c2961a6c0ef57622977b22f50d8a0712 139 Pfam PF02082 Transcriptional regulator 1 82 8.7E-27 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type HW35_04820 c2961a6c0ef57622977b22f50d8a0712 139 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 124 1.7E-34 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type HW35_04820 c2961a6c0ef57622977b22f50d8a0712 139 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site HW35_08740 d3d5d895d49940e38ea8c6e8e1df8cc5 273 Pfam PF00665 Integrase core domain 109 223 8.5E-24 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_08740 d3d5d895d49940e38ea8c6e8e1df8cc5 273 SUPERFAMILY SSF53098 100 263 1.32E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_08740 d3d5d895d49940e38ea8c6e8e1df8cc5 273 Gene3D G3DSA:3.30.420.10 99 271 2.1E-8 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_08740 d3d5d895d49940e38ea8c6e8e1df8cc5 273 Pfam PF13276 HTH-like domain 29 76 1.3E-19 T 12-10-2018 IPR025948 HTH-like domain HW35_16570 9665c05116462574fe14216af90de2ee 251 Gene3D G3DSA:3.60.40.10 1 244 1.4E-71 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_16570 9665c05116462574fe14216af90de2ee 251 SMART SM00331 7 242 6.5E-52 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_16570 9665c05116462574fe14216af90de2ee 251 SMART SM00332 1 240 8.0E-27 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_16570 9665c05116462574fe14216af90de2ee 251 Pfam PF13672 Protein phosphatase 2C 12 205 3.9E-17 T 12-10-2018 HW35_16570 9665c05116462574fe14216af90de2ee 251 SUPERFAMILY SSF81606 2 242 5.23E-64 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HW35_02010 06d2f8aa22a0a6f392af9da9e0fa0dd0 63 Pfam PF17340 Family of unknown function (DUF5370) 1 63 1.6E-35 T 12-10-2018 IPR035314 Protein of unknown function DUF5370 HW35_02010 06d2f8aa22a0a6f392af9da9e0fa0dd0 63 ProDom PD053503 YBXH ORF3 1 63 5.0E-17 T 12-10-2018 IPR035314 Protein of unknown function DUF5370 HW35_05280 1c4eaddb4e3fc25669f424d6b532bb9c 346 Pfam PF14559 Tetratricopeptide repeat 31 77 9.2E-7 T 12-10-2018 HW35_05280 1c4eaddb4e3fc25669f424d6b532bb9c 346 Gene3D G3DSA:1.25.40.10 20 92 2.3E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_05280 1c4eaddb4e3fc25669f424d6b532bb9c 346 SUPERFAMILY SSF48452 25 110 1.22E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_14015 4fdad51d77fe319c27ea57d514eac43d 219 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 13 201 3.8E-34 T 12-10-2018 IPR013343 CRISPR-associated protein Cas4 HW35_14015 4fdad51d77fe319c27ea57d514eac43d 219 Gene3D G3DSA:3.90.320.10 9 202 6.5E-6 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal HW35_14015 4fdad51d77fe319c27ea57d514eac43d 219 Pfam PF01930 Domain of unknown function DUF83 12 201 5.4E-34 T 12-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 HW35_10565 327b463375b8986ffad54e4024c8963a 153 Gene3D G3DSA:1.10.10.1240 2 72 8.1E-37 T 12-10-2018 HW35_10565 327b463375b8986ffad54e4024c8963a 153 Gene3D G3DSA:1.10.1200.150 73 153 1.8E-32 T 12-10-2018 HW35_10565 327b463375b8986ffad54e4024c8963a 153 PIRSF PIRSF010607 1 153 9.3E-68 T 12-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 HW35_10565 327b463375b8986ffad54e4024c8963a 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 150 1.7E-59 T 12-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 HW35_15385 99e94a3b727f7bdb786c983083fe30b2 212 SUPERFAMILY SSF81301 3 199 3.43E-59 T 12-10-2018 HW35_15385 99e94a3b727f7bdb786c983083fe30b2 212 Gene3D G3DSA:1.10.287.860 147 210 2.3E-28 T 12-10-2018 HW35_15385 99e94a3b727f7bdb786c983083fe30b2 212 Pfam PF04607 Region found in RelA / SpoT proteins 43 162 4.9E-38 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 HW35_15385 99e94a3b727f7bdb786c983083fe30b2 212 Gene3D G3DSA:3.30.460.10 1 146 2.5E-52 T 12-10-2018 HW35_15385 99e94a3b727f7bdb786c983083fe30b2 212 SMART SM00954 43 164 1.7E-42 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 HW35_12070 c78a8af9d0cccb735aecf57832af2e81 493 PIRSF PIRSF006005 1 493 1.3E-223 T 12-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12070 c78a8af9d0cccb735aecf57832af2e81 493 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 256 273 - T 12-10-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12070 c78a8af9d0cccb735aecf57832af2e81 493 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 5 491 3.2E-215 T 12-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12070 c78a8af9d0cccb735aecf57832af2e81 493 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 493 258.309 T 12-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 HW35_12070 c78a8af9d0cccb735aecf57832af2e81 493 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 243 437 6.7E-36 T 12-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 HW35_12070 c78a8af9d0cccb735aecf57832af2e81 493 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 19 227 2.6E-35 T 12-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 HW35_01230 c453b40a53c14f5684ec0e9fdf2ce7c8 241 SUPERFAMILY SSF55811 13 212 7.68E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 HW35_01230 c453b40a53c14f5684ec0e9fdf2ce7c8 241 Pfam PF00293 NUDIX domain 24 199 5.7E-10 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HW35_01230 c453b40a53c14f5684ec0e9fdf2ce7c8 241 Gene3D G3DSA:3.90.79.10 18 230 2.6E-57 T 12-10-2018 HW35_08865 a99eee11fe54ed61e9e6135ea1c10f3a 313 Gene3D G3DSA:1.10.260.150 47 313 4.7E-95 T 12-10-2018 HW35_08865 a99eee11fe54ed61e9e6135ea1c10f3a 313 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 84 225 6.9E-51 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HW35_08865 a99eee11fe54ed61e9e6135ea1c10f3a 313 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 83 226 4.1E-53 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HW35_08865 a99eee11fe54ed61e9e6135ea1c10f3a 313 Hamap MF_01140 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU [tagU]. 8 307 50.4 T 12-10-2018 IPR023734 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU HW35_14135 aaeae49c94cfc04bc3535c3c92c4ec03 265 TIGRFAM TIGR00761 argB: acetylglutamate kinase 4 236 4.8E-70 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HW35_14135 aaeae49c94cfc04bc3535c3c92c4ec03 265 Pfam PF00696 Amino acid kinase family 3 237 2.1E-37 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 HW35_14135 aaeae49c94cfc04bc3535c3c92c4ec03 265 Hamap MF_00082 Acetylglutamate kinase [argB]. 1 254 39.195 T 12-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HW35_14135 aaeae49c94cfc04bc3535c3c92c4ec03 265 PIRSF PIRSF000728 1 261 1.2E-82 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HW35_14135 aaeae49c94cfc04bc3535c3c92c4ec03 265 Gene3D G3DSA:3.40.1160.10 1 264 1.8E-71 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_14135 aaeae49c94cfc04bc3535c3c92c4ec03 265 SUPERFAMILY SSF53633 1 259 1.31E-63 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_07070 66cb6d144ad116d1d86eb1b72285a55f 433 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 149 424 4.9E-77 T 12-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 HW35_07070 66cb6d144ad116d1d86eb1b72285a55f 433 Pfam PF01458 Uncharacterized protein family (UPF0051) 183 407 2.1E-65 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 HW35_07070 66cb6d144ad116d1d86eb1b72285a55f 433 SUPERFAMILY SSF101960 11 432 6.15E-123 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily HW35_13905 6bacdaa8ab3251c4eb968cba8d091cbb 83 ProDom PD028055 SPLA TRANSCRIPTIONAL TRANSCRIPTION REGULATOR REGULATION 6 62 1.0E-21 T 12-10-2018 HW35_13905 6bacdaa8ab3251c4eb968cba8d091cbb 83 Pfam PF11132 Transcriptional regulator protein (SplA) 3 74 5.4E-32 T 12-10-2018 IPR022608 Transcription regulator SplA HW35_06385 72130e93055d99f4564d59bf3fa0bed0 272 SUPERFAMILY SSF52096 5 267 1.01E-80 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_06385 72130e93055d99f4564d59bf3fa0bed0 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 2.7E-130 T 12-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 HW35_06385 72130e93055d99f4564d59bf3fa0bed0 272 Gene3D G3DSA:3.90.226.10 1 209 3.9E-78 T 12-10-2018 HW35_06385 72130e93055d99f4564d59bf3fa0bed0 272 Gene3D G3DSA:1.10.12.10 210 260 4.3E-28 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal HW35_06385 72130e93055d99f4564d59bf3fa0bed0 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 55.451 T 12-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 HW35_06385 72130e93055d99f4564d59bf3fa0bed0 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 267 4.4E-92 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 HW35_08635 b6a0957f81cd65c073edd76c7faf6349 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 457 9.0E-74 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HW35_08635 b6a0957f81cd65c073edd76c7faf6349 470 SUPERFAMILY SSF55103 220 459 2.78E-70 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HW35_08635 b6a0957f81cd65c073edd76c7faf6349 470 Pfam PF01565 FAD binding domain 41 180 3.7E-43 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HW35_08635 b6a0957f81cd65c073edd76c7faf6349 470 Gene3D G3DSA:1.10.45.10 418 458 3.5E-13 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HW35_08635 b6a0957f81cd65c073edd76c7faf6349 470 Gene3D G3DSA:3.30.465.40 3 235 3.7E-80 T 12-10-2018 HW35_08635 b6a0957f81cd65c073edd76c7faf6349 470 Gene3D G3DSA:3.30.70.2740 336 417 8.5E-14 T 12-10-2018 HW35_08635 b6a0957f81cd65c073edd76c7faf6349 470 SUPERFAMILY SSF56176 4 217 4.25E-75 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 HW35_08635 b6a0957f81cd65c073edd76c7faf6349 470 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 44 456 1.6E-185 T 12-10-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 HW35_07230 e463eaea518cdcef87c47344af2101cc 99 TIGRFAM TIGR04104 cxxc_20_cxxc: cxxc_20_cxxc protein 2 93 3.1E-21 T 12-10-2018 IPR026369 CxxC-20-CxxC protein HW35_01870 c00730add85541ac92fd75a66d58734b 258 Gene3D G3DSA:3.90.850.10 52 253 1.0E-68 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 HW35_01870 c00730add85541ac92fd75a66d58734b 258 SUPERFAMILY SSF56529 47 250 4.84E-66 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 HW35_01870 c00730add85541ac92fd75a66d58734b 258 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 55 249 3.4E-56 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 HW35_01870 c00730add85541ac92fd75a66d58734b 258 Pfam PF10370 Domain of unknown function (DUF2437) 1 50 4.1E-12 T 12-10-2018 IPR018833 Domain of unknown function DUF2437 HW35_01665 3cdaf7d3b167186f5b546e3b7aaaec9b 326 Pfam PF00491 Arginase family 39 315 5.4E-58 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_01665 3cdaf7d3b167186f5b546e3b7aaaec9b 326 SUPERFAMILY SSF52768 29 322 3.24E-61 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily HW35_01665 3cdaf7d3b167186f5b546e3b7aaaec9b 326 Gene3D G3DSA:3.40.800.10 29 322 1.8E-74 T 12-10-2018 HW35_01665 3cdaf7d3b167186f5b546e3b7aaaec9b 326 PIRSF PIRSF036979 18 323 1.3E-48 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_01665 3cdaf7d3b167186f5b546e3b7aaaec9b 326 PRINTS PR00116 Arginase signature 126 141 2.8E-8 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_01665 3cdaf7d3b167186f5b546e3b7aaaec9b 326 PRINTS PR00116 Arginase signature 242 271 2.8E-8 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 HW35_04365 654181143a2b49a53846a5afbf8cfe34 257 SMART SM00382 29 224 8.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_04365 654181143a2b49a53846a5afbf8cfe34 257 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_04365 654181143a2b49a53846a5afbf8cfe34 257 Gene3D G3DSA:3.40.50.300 1 248 5.6E-66 T 12-10-2018 HW35_04365 654181143a2b49a53846a5afbf8cfe34 257 SUPERFAMILY SSF52540 3 217 7.56E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04365 654181143a2b49a53846a5afbf8cfe34 257 Pfam PF00005 ABC transporter 20 168 1.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_11215 8a4e1e8f2c06b1173b7fb0ddb3e0eb03 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 130 6.0E-16 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HW35_11215 8a4e1e8f2c06b1173b7fb0ddb3e0eb03 140 Gene3D G3DSA:3.10.180.10 2 140 9.9E-54 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_11215 8a4e1e8f2c06b1173b7fb0ddb3e0eb03 140 SUPERFAMILY SSF54593 4 138 5.5E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_08260 a86bd0584fcda4f81772006fd4366036 210 Gene3D G3DSA:3.40.50.360 1 205 1.4E-51 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_08260 a86bd0584fcda4f81772006fd4366036 210 SUPERFAMILY SSF52218 1 205 2.1E-45 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_08260 a86bd0584fcda4f81772006fd4366036 210 Pfam PF02525 Flavodoxin-like fold 2 200 3.1E-42 T 12-10-2018 IPR003680 Flavodoxin-like fold HW35_08260 a86bd0584fcda4f81772006fd4366036 210 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 202 24.536 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 HW35_00155 55d01505861a3110ceadd22297b9b70e 88 Pfam PF04531 Bacteriophage holin 2 88 1.6E-23 T 12-10-2018 IPR006485 Bacteriophage holin HW35_00155 55d01505861a3110ceadd22297b9b70e 88 TIGRFAM TIGR01598 holin_phiLC3: holin, phage phi LC3 family 2 87 2.3E-20 T 12-10-2018 IPR006485 Bacteriophage holin HW35_15860 abfa06380b843613c3e420c4dec94f8b 291 Pfam PF00149 Calcineurin-like phosphoesterase 60 224 9.4E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 HW35_15860 abfa06380b843613c3e420c4dec94f8b 291 SUPERFAMILY SSF56300 59 290 4.68E-35 T 12-10-2018 HW35_15860 abfa06380b843613c3e420c4dec94f8b 291 Gene3D G3DSA:3.60.21.10 60 252 4.1E-23 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like HW35_08880 33697f43630ce87d7b8390690ef86b8a 138 Pfam PF06935 Protein of unknown function (DUF1284) 19 119 2.6E-25 T 12-10-2018 IPR009702 Protein of unknown function DUF1284 HW35_00470 bac27a2623ea82af206feb3ae11d360a 100 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 85 98 3.1E-11 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HW35_00470 bac27a2623ea82af206feb3ae11d360a 100 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 30 46 3.1E-11 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HW35_00470 bac27a2623ea82af206feb3ae11d360a 100 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 64 80 3.1E-11 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HW35_00470 bac27a2623ea82af206feb3ae11d360a 100 Pfam PF02049 Flagellar hook-basal body complex protein FliE 25 100 7.2E-26 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HW35_00470 bac27a2623ea82af206feb3ae11d360a 100 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 4 100 16.201 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HW35_00470 bac27a2623ea82af206feb3ae11d360a 100 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 25 99 3.9E-19 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HW35_14210 112d7b447ea3e1db34eb58046ca64944 67 Pfam PF11755 Protein of unknown function (DUF3311) 7 62 6.4E-19 T 12-10-2018 IPR021741 Protein of unknown function DUF3311 HW35_08460 28c4830b5f190004a11d17e1671a3381 282 Pfam PF09375 Imelysin 47 275 2.3E-40 T 12-10-2018 IPR018976 Imelysin-like domain HW35_08460 28c4830b5f190004a11d17e1671a3381 282 Gene3D G3DSA:1.20.1420.20 38 282 9.4E-93 T 12-10-2018 IPR038352 Imelysin-like domain superfamily HW35_10325 e1ac603775ff5fa92c7e3174168beb3e 140 Gene3D G3DSA:2.40.50.140 1 85 6.4E-30 T 12-10-2018 HW35_10325 e1ac603775ff5fa92c7e3174168beb3e 140 Pfam PF00575 S1 RNA binding domain 4 74 8.9E-22 T 12-10-2018 IPR003029 S1 domain GO:0003676 HW35_10325 e1ac603775ff5fa92c7e3174168beb3e 140 SMART SM00316 4 74 3.0E-26 T 12-10-2018 IPR022967 RNA-binding domain, S1 HW35_10325 e1ac603775ff5fa92c7e3174168beb3e 140 SUPERFAMILY SSF50249 4 87 1.1E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_06275 f7239ac640944b040114e16297c2e747 240 ProDom PD835662 MEMBRANE PROTEIN YYBK 4 199 4.0E-24 T 12-10-2018 IPR024295 Protein of unknown function DUF2705 HW35_06275 f7239ac640944b040114e16297c2e747 240 Pfam PF10920 Protein of unknown function (DUF2705) 5 239 4.1E-50 T 12-10-2018 IPR024295 Protein of unknown function DUF2705 HW35_04120 674734752b923893697ead29cdf76ba9 196 SUPERFAMILY SSF51998 1 175 1.5E-31 T 12-10-2018 HW35_04120 674734752b923893697ead29cdf76ba9 196 Gene3D G3DSA:3.20.70.20 1 126 3.1E-33 T 12-10-2018 HW35_04120 674734752b923893697ead29cdf76ba9 196 Pfam PF02867 Ribonucleotide reductase, barrel domain 2 111 8.5E-19 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HW35_15370 c0ae4a0d1031e232c729919fc5a12c15 136 SUPERFAMILY SSF46458 7 123 3.24E-36 T 12-10-2018 IPR009050 Globin-like superfamily HW35_15370 c0ae4a0d1031e232c729919fc5a12c15 136 Gene3D G3DSA:1.10.490.10 1 131 2.2E-50 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 HW35_15370 c0ae4a0d1031e232c729919fc5a12c15 136 Pfam PF01152 Bacterial-like globin 9 122 2.3E-30 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 HW35_15370 c0ae4a0d1031e232c729919fc5a12c15 136 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 52 76 - T 12-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 HW35_13150 a18860b232c1c37e3f80d4104d013abf 242 SUPERFAMILY SSF52317 1 234 7.32E-66 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_13150 a18860b232c1c37e3f80d4104d013abf 242 Pfam PF06283 Trehalose utilisation 2 217 1.2E-36 T 12-10-2018 IPR029010 ThuA-like domain HW35_13150 a18860b232c1c37e3f80d4104d013abf 242 Gene3D G3DSA:3.40.50.880 1 242 5.0E-116 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like HW35_13150 a18860b232c1c37e3f80d4104d013abf 242 PIRSF PIRSF030013 1 239 7.1E-132 T 12-10-2018 IPR009381 Trehalose catabolism protein, ThuA, prokaryote HW35_03445 2a1762e1fe006c0a3d35990a1fc8eaf1 449 Pfam PF14620 YpeB sporulation 13 371 1.4E-128 T 12-10-2018 IPR014239 Spore germination YpeB GO:0009847 HW35_03445 2a1762e1fe006c0a3d35990a1fc8eaf1 449 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 4 438 9.6E-142 T 12-10-2018 IPR014239 Spore germination YpeB GO:0009847 HW35_01460 968341b3b74b7e5c66ad574adde104ac 240 Gene3D G3DSA:3.40.50.300 64 237 1.7E-43 T 12-10-2018 HW35_01460 968341b3b74b7e5c66ad574adde104ac 240 SMART SM00382 90 224 6.2E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_01460 968341b3b74b7e5c66ad574adde104ac 240 PIRSF PIRSF003073 1 238 2.0E-62 T 12-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HW35_01460 968341b3b74b7e5c66ad574adde104ac 240 SUPERFAMILY SSF52540 86 231 5.71E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_01460 968341b3b74b7e5c66ad574adde104ac 240 Pfam PF01695 IstB-like ATP binding protein 47 222 4.8E-49 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HW35_06700 7fd07fae5713c40d68996d682b0960ea 218 SUPERFAMILY SSF53098 52 212 2.66E-34 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_06700 7fd07fae5713c40d68996d682b0960ea 218 Gene3D G3DSA:3.30.420.10 55 216 3.3E-12 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_06700 7fd07fae5713c40d68996d682b0960ea 218 Pfam PF00665 Integrase core domain 58 172 5.1E-24 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_12470 a1744abe0db28757a43330ce99387859 220 Gene3D G3DSA:3.40.50.300 3 220 2.0E-54 T 12-10-2018 HW35_12470 a1744abe0db28757a43330ce99387859 220 Pfam PF00005 ABC transporter 22 172 1.4E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12470 a1744abe0db28757a43330ce99387859 220 SUPERFAMILY SSF52540 13 216 1.36E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12470 a1744abe0db28757a43330ce99387859 220 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_12470 a1744abe0db28757a43330ce99387859 220 SMART SM00382 31 220 3.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_14935 a02bdd9f55ed52656b664e5635f1ef7c 139 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 12-10-2018 IPR019808 Histidine triad, conserved site HW35_14935 a02bdd9f55ed52656b664e5635f1ef7c 139 Gene3D G3DSA:3.30.428.10 1 139 4.2E-51 T 12-10-2018 IPR036265 HIT-like superfamily HW35_14935 a02bdd9f55ed52656b664e5635f1ef7c 139 PRINTS PR00332 Histidine triad family signature 93 103 3.8E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein HW35_14935 a02bdd9f55ed52656b664e5635f1ef7c 139 PRINTS PR00332 Histidine triad family signature 5 21 3.8E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein HW35_14935 a02bdd9f55ed52656b664e5635f1ef7c 139 PRINTS PR00332 Histidine triad family signature 26 44 3.8E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein HW35_14935 a02bdd9f55ed52656b664e5635f1ef7c 139 SUPERFAMILY SSF54197 2 138 4.49E-47 T 12-10-2018 IPR036265 HIT-like superfamily HW35_14935 a02bdd9f55ed52656b664e5635f1ef7c 139 Pfam PF01230 HIT domain 11 106 1.4E-26 T 12-10-2018 IPR001310 Histidine triad (HIT) protein HW35_07815 38b0569d879d535c274ddbd0fd0a1640 397 SMART SM00228 297 363 8.6E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_07815 38b0569d879d535c274ddbd0fd0a1640 397 Pfam PF13180 PDZ domain 302 353 1.6E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 HW35_07815 38b0569d879d535c274ddbd0fd0a1640 397 Gene3D G3DSA:2.30.42.10 279 371 6.1E-13 T 12-10-2018 HW35_07815 38b0569d879d535c274ddbd0fd0a1640 397 SUPERFAMILY SSF50156 305 387 5.65E-14 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 HW35_05535 fdd0e3e1d1be3d376bc75b9ffd882b6c 253 SMART SM00967 31 100 6.1E-12 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HW35_05535 fdd0e3e1d1be3d376bc75b9ffd882b6c 253 SUPERFAMILY SSF75217 89 249 6.15E-40 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases HW35_05535 fdd0e3e1d1be3d376bc75b9ffd882b6c 253 SUPERFAMILY SSF55315 2 98 2.47E-23 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like HW35_05535 fdd0e3e1d1be3d376bc75b9ffd882b6c 253 Gene3D G3DSA:3.30.1330.30 3 98 3.5E-24 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like HW35_05535 fdd0e3e1d1be3d376bc75b9ffd882b6c 253 Gene3D G3DSA:3.40.1280.10 99 252 5.1E-49 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HW35_05535 fdd0e3e1d1be3d376bc75b9ffd882b6c 253 Pfam PF00588 SpoU rRNA Methylase family 109 247 1.1E-35 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HW35_05535 fdd0e3e1d1be3d376bc75b9ffd882b6c 253 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 98 4.7E-10 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HW35_17710 6e1a87697713ae8dae8d4877cce761b7 480 Pfam PF00171 Aldehyde dehydrogenase family 17 473 5.9E-164 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 HW35_17710 6e1a87697713ae8dae8d4877cce761b7 480 Gene3D G3DSA:3.40.309.10 258 445 8.7E-156 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 HW35_17710 6e1a87697713ae8dae8d4877cce761b7 480 SUPERFAMILY SSF53720 6 477 5.24E-148 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HW35_17710 6e1a87697713ae8dae8d4877cce761b7 480 Gene3D G3DSA:3.40.605.10 16 468 8.7E-156 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_10610 df89f055597dcc395854dc25f2f4f989 222 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 HW35_10610 df89f055597dcc395854dc25f2f4f989 222 SUPERFAMILY SSF51161 3 168 2.77E-59 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily HW35_10610 df89f055597dcc395854dc25f2f4f989 222 Gene3D G3DSA:1.10.3130.10 1 66 2.5E-25 T 12-10-2018 HW35_10610 df89f055597dcc395854dc25f2f4f989 222 PIRSF PIRSF000441 1 218 4.0E-87 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 HW35_10610 df89f055597dcc395854dc25f2f4f989 222 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 166 5.6E-80 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 HW35_10610 df89f055597dcc395854dc25f2f4f989 222 Gene3D G3DSA:2.160.10.10 67 182 3.7E-38 T 12-10-2018 HW35_10610 df89f055597dcc395854dc25f2f4f989 222 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 1.1E-4 T 12-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 HW35_10610 df89f055597dcc395854dc25f2f4f989 222 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 5.2E-6 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_10610 df89f055597dcc395854dc25f2f4f989 222 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 3.0E-8 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_15845 c6f1c044ac3a79d25b3ef6f83f92f4e8 92 Gene3D G3DSA:1.10.10.60 8 86 1.2E-8 T 12-10-2018 HW35_15845 c6f1c044ac3a79d25b3ef6f83f92f4e8 92 SUPERFAMILY SSF46689 4 91 1.43E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_15845 c6f1c044ac3a79d25b3ef6f83f92f4e8 92 Pfam PF01527 Transposase 1 74 8.3E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_03390 4d1df45ff2bd548bb635587a1abc0d59 61 Pfam PF10966 Protein of unknown function (DUF2768) 7 61 1.8E-18 T 12-10-2018 IPR020076 Protein of unknown function DUF2768 HW35_03390 4d1df45ff2bd548bb635587a1abc0d59 61 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 1 61 6.0E-9 T 12-10-2018 IPR020076 Protein of unknown function DUF2768 HW35_16540 607ecc1502c8d2b25286362511a1c86e 404 SUPERFAMILY SSF102645 185 398 1.83E-79 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 HW35_16540 607ecc1502c8d2b25286362511a1c86e 404 Gene3D G3DSA:3.40.50.10300 187 401 1.6E-87 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 HW35_16540 607ecc1502c8d2b25286362511a1c86e 404 Gene3D G3DSA:3.40.50.1950 1 186 1.2E-63 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 HW35_16540 607ecc1502c8d2b25286362511a1c86e 404 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 369 2.4E-74 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 HW35_16540 607ecc1502c8d2b25286362511a1c86e 404 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 394 3.6E-158 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 HW35_16540 607ecc1502c8d2b25286362511a1c86e 404 Pfam PF02441 Flavoprotein 5 176 3.5E-49 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 HW35_16540 607ecc1502c8d2b25286362511a1c86e 404 SUPERFAMILY SSF52507 1 177 8.63E-64 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 HW35_15100 7fa6059ffec95c051ab4eade06a72b8b 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 1.1E-27 T 12-10-2018 IPR019618 Spore germination protein GerPA/GerPF HW35_12945 bc743d779a6bd8deb5840cda66bf2982 232 Pfam PF01522 Polysaccharide deacetylase 42 157 1.0E-31 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HW35_12945 bc743d779a6bd8deb5840cda66bf2982 232 SUPERFAMILY SSF88713 26 231 1.04E-53 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HW35_12945 bc743d779a6bd8deb5840cda66bf2982 232 Gene3D G3DSA:3.20.20.370 22 232 2.1E-55 T 12-10-2018 HW35_13645 938df777dd47891d8d531d0e71602ce0 423 Pfam PF07690 Major Facilitator Superfamily 21 378 1.8E-43 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_13645 938df777dd47891d8d531d0e71602ce0 423 SUPERFAMILY SSF103473 8 419 6.02E-56 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_13645 938df777dd47891d8d531d0e71602ce0 423 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 79 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HW35_13645 938df777dd47891d8d531d0e71602ce0 423 Gene3D G3DSA:1.20.1250.20 14 411 1.6E-49 T 12-10-2018 HW35_09305 819b8bdbb85f1a3f1335d405db8583ba 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 3.0E-12 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 HW35_09305 819b8bdbb85f1a3f1335d405db8583ba 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 7.9E-26 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 HW35_09305 819b8bdbb85f1a3f1335d405db8583ba 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 1.2E-27 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 HW35_09305 819b8bdbb85f1a3f1335d405db8583ba 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 19.913 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 122 2.1E-34 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 237 4.3E-9 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 SUPERFAMILY SSF55347 128 315 9.97E-36 T 12-10-2018 HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 Gene3D G3DSA:3.40.50.720 6 314 1.0E-104 T 12-10-2018 HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 112 126 9.7E-7 T 12-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 50 66 9.7E-7 T 12-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 1 11 9.7E-7 T 12-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 251 266 9.7E-7 T 12-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 307 323 9.7E-7 T 12-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 SUPERFAMILY SSF51735 3 154 2.92E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_13155 220bc4c01793cba4e489413fd1581c3d 343 Gene3D G3DSA:3.30.360.10 127 335 1.0E-104 T 12-10-2018 HW35_16040 22548e324a32ffa4a95eb6e044169ef6 151 Gene3D G3DSA:2.30.110.10 1 150 5.5E-64 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 HW35_16040 22548e324a32ffa4a95eb6e044169ef6 151 SUPERFAMILY SSF50475 14 113 1.63E-12 T 12-10-2018 HW35_16040 22548e324a32ffa4a95eb6e044169ef6 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 93 1.2E-10 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 HW35_00460 a5b99e70dbc537742197efd1ffbc1300 130 PIRSF PIRSF002889 1 129 4.5E-33 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 HW35_00460 a5b99e70dbc537742197efd1ffbc1300 130 Pfam PF00460 Flagella basal body rod protein 9 34 6.8E-9 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HW35_00460 a5b99e70dbc537742197efd1ffbc1300 130 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 3 127 2.5E-34 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 HW35_03910 ffe3a9f46c8f75c5e9169b217bcf581d 302 Gene3D G3DSA:3.40.718.10 4 301 7.9E-105 T 12-10-2018 HW35_03910 ffe3a9f46c8f75c5e9169b217bcf581d 302 SUPERFAMILY SSF53659 3 299 5.76E-64 T 12-10-2018 HW35_03910 ffe3a9f46c8f75c5e9169b217bcf581d 302 PIRSF PIRSF000428 1 302 7.5E-85 T 12-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HW35_03910 ffe3a9f46c8f75c5e9169b217bcf581d 302 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 3 300 2.8E-131 T 12-10-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 HW35_03910 ffe3a9f46c8f75c5e9169b217bcf581d 302 Pfam PF01515 Phosphate acetyl/butaryl transferase 73 296 4.3E-47 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HW35_09615 118c556337ae7ffa505474b757a5965a 205 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 8 197 1.4E-51 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 HW35_09615 118c556337ae7ffa505474b757a5965a 205 Pfam PF02592 Putative vitamin uptake transporter 33 192 6.0E-50 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 HW35_09615 118c556337ae7ffa505474b757a5965a 205 Hamap MF_02088 Probable queuosine precursor transporter. 1 205 17.314 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 HW35_17155 f5a403235b5ef623959b2c906d4b9bd6 201 Pfam PF03458 UPF0126 domain 92 161 1.8E-18 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 HW35_17155 f5a403235b5ef623959b2c906d4b9bd6 201 Pfam PF03458 UPF0126 domain 5 78 3.8E-19 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 HW35_13170 b61d3d757ea14fb2ad1823f769609a4d 230 Pfam PF04854 Protein of unknown function, DUF624 21 121 6.3E-20 T 12-10-2018 IPR006938 Protein of unknown function DUF624 HW35_00990 93ab9219d1a7c06ed043fc8c6dc1a90c 46 Pfam PF08177 Small acid-soluble spore protein N family 6 45 2.0E-20 T 12-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 HW35_00990 93ab9219d1a7c06ed043fc8c6dc1a90c 46 Hamap MF_01505 Small, acid-soluble spore protein N [sspN]. 1 46 14.854 T 12-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 HW35_03405 5c3656632f3ee941b8234fb8c29d0bff 202 PIRSF PIRSF036710 1 202 3.3E-49 T 12-10-2018 IPR014617 Predicted membrane protein, Bacillus YphA type HW35_11370 d19b5e0c3928db5f1b55ae232101ade6 393 Pfam PF01098 Cell cycle protein 13 381 4.7E-92 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_02745 3a6c10a42c914c15ba1c35ced7ce7cd4 453 SUPERFAMILY SSF53383 12 436 3.75E-123 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_02745 3a6c10a42c914c15ba1c35ced7ce7cd4 453 Pfam PF00202 Aminotransferase class-III 16 435 1.5E-111 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_02745 3a6c10a42c914c15ba1c35ced7ce7cd4 453 PIRSF PIRSF000521 10 439 5.5E-41 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HW35_02745 3a6c10a42c914c15ba1c35ced7ce7cd4 453 Gene3D G3DSA:3.40.640.10 50 325 3.0E-151 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_02745 3a6c10a42c914c15ba1c35ced7ce7cd4 453 Gene3D G3DSA:3.90.1150.10 16 435 3.0E-151 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HW35_05640 93b503fefeb030def50c95f64670eb9b 238 Gene3D G3DSA:3.40.50.2300 1 121 4.6E-39 T 12-10-2018 HW35_05640 93b503fefeb030def50c95f64670eb9b 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 232 6.2E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_05640 93b503fefeb030def50c95f64670eb9b 238 SUPERFAMILY SSF52172 2 128 8.97E-42 T 12-10-2018 IPR011006 CheY-like superfamily HW35_05640 93b503fefeb030def50c95f64670eb9b 238 Pfam PF00072 Response regulator receiver domain 5 114 2.4E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_05640 93b503fefeb030def50c95f64670eb9b 238 SUPERFAMILY SSF46894 130 233 9.92E-33 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_05640 93b503fefeb030def50c95f64670eb9b 238 SMART SM00862 156 232 5.4E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_05640 93b503fefeb030def50c95f64670eb9b 238 Gene3D G3DSA:1.10.10.10 122 236 8.3E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_05640 93b503fefeb030def50c95f64670eb9b 238 SMART SM00448 3 114 1.3E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_17385 6fdd299c6815ea341dd5adedd6ccb5f1 352 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 345 3.4E-71 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HW35_17385 6fdd299c6815ea341dd5adedd6ccb5f1 352 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 181 343 1.6E-29 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HW35_17385 6fdd299c6815ea341dd5adedd6ccb5f1 352 Gene3D G3DSA:3.30.300.210 196 347 5.9E-26 T 12-10-2018 IPR038501 Spore germination GerAC superfamily HW35_14160 f879c5c576243bc02b428facbf2fad43 405 SUPERFAMILY SSF69864 171 398 4.05E-95 T 12-10-2018 HW35_14160 f879c5c576243bc02b428facbf2fad43 405 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 397 55.445 T 12-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HW35_14160 f879c5c576243bc02b428facbf2fad43 405 SUPERFAMILY SSF52402 3 205 1.59E-45 T 12-10-2018 HW35_14160 f879c5c576243bc02b428facbf2fad43 405 Gene3D G3DSA:1.20.5.470 363 396 1.2E-10 T 12-10-2018 HW35_14160 f879c5c576243bc02b428facbf2fad43 405 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 395 6.4E-169 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HW35_14160 f879c5c576243bc02b428facbf2fad43 405 Gene3D G3DSA:3.90.1260.10 64 353 8.6E-153 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HW35_14160 f879c5c576243bc02b428facbf2fad43 405 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HW35_14160 f879c5c576243bc02b428facbf2fad43 405 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HW35_14160 f879c5c576243bc02b428facbf2fad43 405 Gene3D G3DSA:3.40.50.620 6 172 8.6E-153 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_14160 f879c5c576243bc02b428facbf2fad43 405 Pfam PF00764 Arginosuccinate synthase 7 392 1.9E-178 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HW35_01845 30977e9095165eb673ebb69ca0059406 308 Pfam PF00892 EamA-like transporter family 11 142 1.2E-27 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_01845 30977e9095165eb673ebb69ca0059406 308 Pfam PF00892 EamA-like transporter family 159 290 3.5E-27 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_01845 30977e9095165eb673ebb69ca0059406 308 SUPERFAMILY SSF103481 41 144 7.59E-18 T 12-10-2018 HW35_01845 30977e9095165eb673ebb69ca0059406 308 SUPERFAMILY SSF103481 191 295 6.8E-18 T 12-10-2018 HW35_09680 702ba0a5848f8b90f7a8ec55d4c713fd 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_09680 702ba0a5848f8b90f7a8ec55d4c713fd 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_09680 702ba0a5848f8b90f7a8ec55d4c713fd 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_09680 702ba0a5848f8b90f7a8ec55d4c713fd 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.8E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HW35_09680 702ba0a5848f8b90f7a8ec55d4c713fd 290 Pfam PF03466 LysR substrate binding domain 122 286 2.1E-16 T 12-10-2018 IPR005119 LysR, substrate-binding HW35_09680 702ba0a5848f8b90f7a8ec55d4c713fd 290 Gene3D G3DSA:3.40.190.290 118 289 3.3E-13 T 12-10-2018 HW35_09680 702ba0a5848f8b90f7a8ec55d4c713fd 290 SUPERFAMILY SSF53850 121 286 5.07E-16 T 12-10-2018 HW35_09680 702ba0a5848f8b90f7a8ec55d4c713fd 290 SUPERFAMILY SSF46785 1 78 8.17E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_09680 702ba0a5848f8b90f7a8ec55d4c713fd 290 Gene3D G3DSA:1.10.10.10 2 90 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_10865 8f8b9c1f28800c47640f275a2cbd8b07 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 37.8 T 12-10-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0016021|GO:0022857|GO:0055085 HW35_10865 8f8b9c1f28800c47640f275a2cbd8b07 265 Pfam PF02361 Cobalt transport protein 15 237 4.1E-59 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component HW35_17185 6dfec522c16581706d506f132c6a1c67 107 Pfam PF01476 LysM domain 41 90 3.1E-6 T 12-10-2018 IPR018392 LysM domain HW35_17185 6dfec522c16581706d506f132c6a1c67 107 Gene3D G3DSA:3.10.350.10 26 99 2.0E-10 T 12-10-2018 IPR036779 LysM domain superfamily HW35_17185 6dfec522c16581706d506f132c6a1c67 107 SUPERFAMILY SSF54106 37 91 3.79E-5 T 12-10-2018 HW35_16080 93d92b43d842d510beb2a3f2a334d3a3 277 SUPERFAMILY SSF53098 108 272 1.67E-32 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_16080 93d92b43d842d510beb2a3f2a334d3a3 277 Gene3D G3DSA:3.30.420.10 111 269 1.9E-12 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_16080 93d92b43d842d510beb2a3f2a334d3a3 277 Pfam PF13276 HTH-like domain 39 92 2.4E-15 T 12-10-2018 IPR025948 HTH-like domain HW35_16080 93d92b43d842d510beb2a3f2a334d3a3 277 Pfam PF00665 Integrase core domain 115 229 9.0E-25 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_08970 c26c9d5fc3a6c7bcb6bc76b0175e2b65 91 Pfam PF12116 Stage III sporulation protein D 2 82 1.3E-41 T 12-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID HW35_08970 c26c9d5fc3a6c7bcb6bc76b0175e2b65 91 Gene3D G3DSA:1.10.10.60 1 91 1.3E-42 T 12-10-2018 HW35_08970 c26c9d5fc3a6c7bcb6bc76b0175e2b65 91 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 HW35_08970 c26c9d5fc3a6c7bcb6bc76b0175e2b65 91 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 81 2.6E-46 T 12-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID HW35_04295 56f17068ff959f63de0f9c2eb0a4f4c6 271 Gene3D G3DSA:3.40.50.300 25 267 5.1E-62 T 12-10-2018 HW35_04295 56f17068ff959f63de0f9c2eb0a4f4c6 271 SMART SM00382 49 243 9.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_04295 56f17068ff959f63de0f9c2eb0a4f4c6 271 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_04295 56f17068ff959f63de0f9c2eb0a4f4c6 271 SUPERFAMILY SSF52540 18 258 2.13E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04295 56f17068ff959f63de0f9c2eb0a4f4c6 271 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 25 271 5.2E-126 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 HW35_04295 56f17068ff959f63de0f9c2eb0a4f4c6 271 Pfam PF00005 ABC transporter 40 196 5.9E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_12960 04f55b4be6c67ea051cc35f3677381b4 257 Pfam PF00756 Putative esterase 11 251 4.1E-27 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 HW35_12960 04f55b4be6c67ea051cc35f3677381b4 257 Gene3D G3DSA:3.40.50.1820 2 257 4.5E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_12960 04f55b4be6c67ea051cc35f3677381b4 257 SUPERFAMILY SSF53474 3 255 5.45E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_03820 849c16f716ff573b7d77523a1bed5abb 339 SUPERFAMILY SSF51395 4 333 1.27E-119 T 12-10-2018 HW35_03820 849c16f716ff573b7d77523a1bed5abb 339 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 324 1.6E-96 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 HW35_03820 849c16f716ff573b7d77523a1bed5abb 339 Gene3D G3DSA:3.20.20.70 2 338 4.3E-133 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_03820 849c16f716ff573b7d77523a1bed5abb 339 Hamap MF_01614 NADPH dehydrogenase [namA]. 2 338 68.105 T 12-10-2018 IPR023663 NADPH dehydrogenase GO:0003959|GO:0055114 HW35_02280 67eb836dba58cfdd10e1f6c6e9b5e20e 362 Pfam PF04230 Polysaccharide pyruvyl transferase 14 293 1.8E-28 T 12-10-2018 IPR007345 Polysaccharide pyruvyl transferase HW35_14540 00e1d3ec9b90cd384dd4b1bde40cb08b 82 Pfam PF03413 Peptidase propeptide and YPEB domain 18 76 6.8E-11 T 12-10-2018 IPR025711 PepSY domain HW35_14540 00e1d3ec9b90cd384dd4b1bde40cb08b 82 Gene3D G3DSA:3.10.450.40 12 78 1.3E-15 T 12-10-2018 HW35_13925 52952c1eb0efe0da2ec4afc5c20147a8 122 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 119 18.457 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 HW35_13925 52952c1eb0efe0da2ec4afc5c20147a8 122 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 114 1.1E-25 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 HW35_13925 52952c1eb0efe0da2ec4afc5c20147a8 122 TIGRFAM TIGR00494 crcB: protein CrcB 7 117 1.6E-27 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 HW35_09005 e0c98c4e1637e9d5345b9a0f8aab6d73 436 Gene3D G3DSA:3.65.10.10 6 415 4.2E-176 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 HW35_09005 e0c98c4e1637e9d5345b9a0f8aab6d73 436 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 9.6E-178 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_09005 e0c98c4e1637e9d5345b9a0f8aab6d73 436 Gene3D G3DSA:3.65.10.10 20 231 4.2E-176 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 HW35_09005 e0c98c4e1637e9d5345b9a0f8aab6d73 436 SUPERFAMILY SSF55205 2 418 3.27E-145 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HW35_09005 e0c98c4e1637e9d5345b9a0f8aab6d73 436 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 407 4.8E-117 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HW35_09005 e0c98c4e1637e9d5345b9a0f8aab6d73 436 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.779 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HW35_15865 236324fef3282f48b3316404ddc3e3c4 403 Gene3D G3DSA:1.20.5.170 245 289 4.4E-12 T 12-10-2018 HW35_15865 236324fef3282f48b3316404ddc3e3c4 403 Pfam PF10388 EAL-domain associated signalling protein domain 239 403 4.2E-73 T 12-10-2018 IPR018842 YkuI, C-terminal HW35_15865 236324fef3282f48b3316404ddc3e3c4 403 SMART SM00052 1 240 4.9E-10 T 12-10-2018 IPR001633 EAL domain HW35_15865 236324fef3282f48b3316404ddc3e3c4 403 SUPERFAMILY SSF103190 264 399 3.22E-39 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily HW35_15865 236324fef3282f48b3316404ddc3e3c4 403 Gene3D G3DSA:3.30.450.20 290 403 5.6E-46 T 12-10-2018 HW35_15865 236324fef3282f48b3316404ddc3e3c4 403 Pfam PF00563 EAL domain 10 235 2.4E-32 T 12-10-2018 IPR001633 EAL domain HW35_15865 236324fef3282f48b3316404ddc3e3c4 403 SUPERFAMILY SSF141868 3 241 3.4E-38 T 12-10-2018 IPR035919 EAL domain superfamily HW35_15865 236324fef3282f48b3316404ddc3e3c4 403 Gene3D G3DSA:3.20.20.450 1 228 2.9E-54 T 12-10-2018 IPR035919 EAL domain superfamily HW35_00680 3eddd60fe7b6d119902a6215d64e7235 172 TIGRFAM TIGR02359 thiW: energy coupling factor transporter S component ThiW 6 158 1.8E-51 T 12-10-2018 IPR012652 Energy coupling factor transporter S component ThiW HW35_00680 3eddd60fe7b6d119902a6215d64e7235 172 PIRSF PIRSF024534 1 165 7.1E-56 T 12-10-2018 IPR012652 Energy coupling factor transporter S component ThiW HW35_00680 3eddd60fe7b6d119902a6215d64e7235 172 Pfam PF09512 Thiamine-precursor transporter protein (ThiW) 7 153 3.0E-55 T 12-10-2018 IPR012652 Energy coupling factor transporter S component ThiW HW35_00680 3eddd60fe7b6d119902a6215d64e7235 172 Gene3D G3DSA:1.10.1760.20 3 168 9.8E-14 T 12-10-2018 HW35_03665 cf4f0319976618f685e38659de7149a2 206 Gene3D G3DSA:2.60.480.10 1 95 8.5E-13 T 12-10-2018 IPR038548 Stage V sporulation protein AA, N-terminal domain superfamily HW35_03665 cf4f0319976618f685e38659de7149a2 206 Pfam PF12164 Stage V sporulation protein AA 4 88 3.0E-21 T 12-10-2018 IPR021997 Stage V sporulation protein AA HW35_02300 3fd1152876b9baefe0804438c1012168 277 Pfam PF00665 Integrase core domain 117 228 1.4E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_02300 3fd1152876b9baefe0804438c1012168 277 Pfam PF13276 HTH-like domain 34 87 2.2E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_02300 3fd1152876b9baefe0804438c1012168 277 Gene3D G3DSA:3.30.420.10 115 258 2.7E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_02300 3fd1152876b9baefe0804438c1012168 277 SUPERFAMILY SSF53098 119 270 8.5E-32 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_10570 15cb6a56103c8e2913e32a03d4d60820 183 PIRSF PIRSF015034 1 181 3.4E-67 T 12-10-2018 IPR025542 YacH protein HW35_10570 15cb6a56103c8e2913e32a03d4d60820 183 Pfam PF02151 UvrB/uvrC motif 139 172 1.3E-7 T 12-10-2018 IPR001943 UVR domain GO:0005515 HW35_10570 15cb6a56103c8e2913e32a03d4d60820 183 SUPERFAMILY SSF46600 138 174 7.32E-6 T 12-10-2018 IPR036876 UVR domain superfamily HW35_10570 15cb6a56103c8e2913e32a03d4d60820 183 Gene3D G3DSA:4.10.860.10 135 182 1.7E-6 T 12-10-2018 HW35_05065 1cc6b036b4723d255e3ffaeb52c91889 259 Gene3D G3DSA:2.70.70.10 126 256 4.5E-21 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_05065 1cc6b036b4723d255e3ffaeb52c91889 259 SUPERFAMILY SSF51261 97 226 1.88E-17 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_05065 1cc6b036b4723d255e3ffaeb52c91889 259 Pfam PF01551 Peptidase family M23 157 252 4.1E-18 T 12-10-2018 IPR016047 Peptidase M23 HW35_13035 857d1e50de16a2d7b4dd71682808e99f 486 Pfam PF00171 Aldehyde dehydrogenase family 25 482 6.0E-176 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 HW35_13035 857d1e50de16a2d7b4dd71682808e99f 486 Gene3D G3DSA:3.40.605.10 16 480 9.5E-182 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 HW35_13035 857d1e50de16a2d7b4dd71682808e99f 486 SUPERFAMILY SSF53720 6 485 7.98E-168 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HW35_13035 857d1e50de16a2d7b4dd71682808e99f 486 Gene3D G3DSA:3.40.309.10 261 452 9.5E-182 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 HW35_13035 857d1e50de16a2d7b4dd71682808e99f 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 HW35_13035 857d1e50de16a2d7b4dd71682808e99f 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 HW35_07055 215392d3ff7ce25075212ec09b54e604 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 2.0E-75 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 HW35_07055 215392d3ff7ce25075212ec09b54e604 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 2.0E-231 T 12-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 HW35_07055 215392d3ff7ce25075212ec09b54e604 465 SUPERFAMILY SSF101960 32 462 4.45E-141 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily HW35_10305 5b4ceef64d53abb0c99d72a94dcece88 92 SUPERFAMILY SSF55174 1 77 2.75E-20 T 12-10-2018 HW35_10305 5b4ceef64d53abb0c99d72a94dcece88 92 Gene3D G3DSA:3.10.290.10 1 91 2.3E-25 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HW35_10305 5b4ceef64d53abb0c99d72a94dcece88 92 Pfam PF01479 S4 domain 1 47 1.3E-9 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10305 5b4ceef64d53abb0c99d72a94dcece88 92 SMART SM00363 1 57 2.3E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HW35_10305 5b4ceef64d53abb0c99d72a94dcece88 92 PIRSF PIRSF038881 1 88 7.4E-33 T 12-10-2018 IPR025490 RNA-binding protein, HP1423 type HW35_01350 26c1ada1737e30be222271d066420055 380 Gene3D G3DSA:3.20.20.30 1 359 9.7E-144 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 HW35_01350 26c1ada1737e30be222271d066420055 380 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 347 1.7E-189 T 12-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 HW35_01350 26c1ada1737e30be222271d066420055 380 Pfam PF00296 Luciferase-like monooxygenase 1 323 1.3E-91 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 HW35_01350 26c1ada1737e30be222271d066420055 380 SUPERFAMILY SSF51679 1 348 3.14E-96 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 HW35_01350 26c1ada1737e30be222271d066420055 380 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 1 377 77.619 T 12-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 HW35_06260 3e80bf7c51df7fa2aa38c3f01e6255df 186 SUPERFAMILY SSF48295 36 118 5.02E-15 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HW35_06260 3e80bf7c51df7fa2aa38c3f01e6255df 186 Pfam PF13518 Helix-turn-helix domain 66 118 5.2E-6 T 12-10-2018 HW35_02780 76fed2d3beaf73d44168a0d0ecc33710 191 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 3 187 6.1E-62 T 12-10-2018 IPR018672 Protein of unknown function DUF2140 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 SUPERFAMILY SSF63520 180 276 1.31E-24 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 SUPERFAMILY SSF63520 58 170 7.19E-28 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 Gene3D G3DSA:1.20.890.100 169 223 2.5E-23 T 12-10-2018 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 SMART SM01061 4 62 5.6E-25 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 Gene3D G3DSA:1.20.58.1950 225 277 5.2E-25 T 12-10-2018 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 Gene3D G3DSA:1.10.1790.10 70 168 1.5E-28 T 12-10-2018 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 Gene3D G3DSA:2.30.24.10 1 69 1.1E-24 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 Pfam PF00874 PRD domain 184 274 1.3E-20 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 Pfam PF00874 PRD domain 81 166 1.6E-22 T 12-10-2018 IPR011608 PRD domain GO:0006355 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 SUPERFAMILY SSF50151 5 56 2.22E-16 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 HW35_11640 73b7d4f37a0e07f4ba81b062d99183db 280 Pfam PF03123 CAT RNA binding domain 5 60 1.3E-22 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 HW35_07790 6759cc159fb88d1d90a2fd185872f6eb 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 254 1.9E-70 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_07790 6759cc159fb88d1d90a2fd185872f6eb 259 SMART SM00062 33 255 3.6E-75 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_07790 6759cc159fb88d1d90a2fd185872f6eb 259 Gene3D G3DSA:3.40.190.10 119 211 2.7E-74 T 12-10-2018 HW35_07790 6759cc159fb88d1d90a2fd185872f6eb 259 SUPERFAMILY SSF53850 1 255 6.58E-71 T 12-10-2018 HW35_07790 6759cc159fb88d1d90a2fd185872f6eb 259 SMART SM00079 33 254 4.3E-4 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HW35_07790 6759cc159fb88d1d90a2fd185872f6eb 259 Gene3D G3DSA:3.40.190.10 35 253 2.7E-74 T 12-10-2018 HW35_05245 43611c249713b348018cd927fcf4d613 162 ProDom PD104119 YSXD OB2071 ORFY 1 162 2.0E-19 T 12-10-2018 HW35_06085 bf1e193202ad9287be4fe9571b1051c0 144 Gene3D G3DSA:1.20.1260.10 2 144 3.9E-53 T 12-10-2018 IPR012347 Ferritin-like HW35_06085 bf1e193202ad9287be4fe9571b1051c0 144 PIRSF PIRSF005900 1 144 8.5E-49 T 12-10-2018 IPR002177 DNA-binding protein Dps HW35_06085 bf1e193202ad9287be4fe9571b1051c0 144 Pfam PF00210 Ferritin-like domain 6 143 1.5E-30 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 HW35_06085 bf1e193202ad9287be4fe9571b1051c0 144 SUPERFAMILY SSF47240 3 143 1.01E-46 T 12-10-2018 IPR009078 Ferritin-like superfamily HW35_06085 bf1e193202ad9287be4fe9571b1051c0 144 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 25 41 1.8E-13 T 12-10-2018 IPR002177 DNA-binding protein Dps HW35_06085 bf1e193202ad9287be4fe9571b1051c0 144 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 49 65 1.8E-13 T 12-10-2018 IPR002177 DNA-binding protein Dps HW35_06085 bf1e193202ad9287be4fe9571b1051c0 144 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 120 138 1.8E-13 T 12-10-2018 IPR002177 DNA-binding protein Dps HW35_06085 bf1e193202ad9287be4fe9571b1051c0 144 ProSitePatterns PS00818 Dps protein family signature 1. 25 41 - T 12-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 HW35_01475 368bc3c5e2f6eaf75d0c218298d50616 259 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 35 41 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HW35_01475 368bc3c5e2f6eaf75d0c218298d50616 259 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 31 45 1.1E-39 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HW35_01475 368bc3c5e2f6eaf75d0c218298d50616 259 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 79 99 1.1E-39 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HW35_01475 368bc3c5e2f6eaf75d0c218298d50616 259 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 208 226 1.1E-39 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HW35_01475 368bc3c5e2f6eaf75d0c218298d50616 259 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 231 251 1.1E-39 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HW35_01475 368bc3c5e2f6eaf75d0c218298d50616 259 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 189 206 1.1E-39 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HW35_01475 368bc3c5e2f6eaf75d0c218298d50616 259 Pfam PF01555 DNA methylase 32 247 1.5E-54 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 HW35_01475 368bc3c5e2f6eaf75d0c218298d50616 259 Gene3D G3DSA:3.40.50.150 13 251 1.7E-67 T 12-10-2018 HW35_01475 368bc3c5e2f6eaf75d0c218298d50616 259 SUPERFAMILY SSF53335 9 257 3.18E-66 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_07400 5b52ff173625c522838340fa2b8ff9ff 510 SUPERFAMILY SSF64158 77 310 1.24E-93 T 12-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07400 5b52ff173625c522838340fa2b8ff9ff 510 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 299 1.7E-84 T 12-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07400 5b52ff173625c522838340fa2b8ff9ff 510 Gene3D G3DSA:3.40.720.10 5 509 1.6E-237 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 HW35_07400 5b52ff173625c522838340fa2b8ff9ff 510 Gene3D G3DSA:3.40.1450.10 77 312 1.6E-237 T 12-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07400 5b52ff173625c522838340fa2b8ff9ff 510 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 509 9.1E-212 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07400 5b52ff173625c522838340fa2b8ff9ff 510 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 510 50.032 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_07400 5b52ff173625c522838340fa2b8ff9ff 510 SUPERFAMILY SSF53649 5 509 5.63E-78 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 HW35_07400 5b52ff173625c522838340fa2b8ff9ff 510 Pfam PF01676 Metalloenzyme superfamily 5 498 1.1E-81 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 HW35_07400 5b52ff173625c522838340fa2b8ff9ff 510 PIRSF PIRSF001492 1 510 5.7E-208 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HW35_10900 857decfb1bd5f99a54622e97e696e3a6 232 SUPERFAMILY SSF52540 5 219 7.92E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10900 857decfb1bd5f99a54622e97e696e3a6 232 Pfam PF00005 ABC transporter 23 165 2.8E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_10900 857decfb1bd5f99a54622e97e696e3a6 232 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_10900 857decfb1bd5f99a54622e97e696e3a6 232 SMART SM00382 32 215 2.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_10900 857decfb1bd5f99a54622e97e696e3a6 232 Gene3D G3DSA:3.40.50.300 1 229 2.6E-47 T 12-10-2018 HW35_10795 ffdab3df18ffff24b752d3f748bacf06 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 6.4E-54 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10795 ffdab3df18ffff24b752d3f748bacf06 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 31.22 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10795 ffdab3df18ffff24b752d3f748bacf06 120 SUPERFAMILY SSF53137 7 118 1.44E-57 T 12-10-2018 HW35_10795 ffdab3df18ffff24b752d3f748bacf06 120 Gene3D G3DSA:3.30.420.100 5 120 3.5E-48 T 12-10-2018 HW35_10795 ffdab3df18ffff24b752d3f748bacf06 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 2.4E-49 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_16780 08ff380bb0760da6d3b8cce37f25a23e 185 Gene3D G3DSA:1.10.132.20 12 182 2.5E-71 T 12-10-2018 HW35_16780 08ff380bb0760da6d3b8cce37f25a23e 185 SUPERFAMILY SSF55194 4 184 1.57E-73 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 HW35_16780 08ff380bb0760da6d3b8cce37f25a23e 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 8.1E-77 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 HW35_16780 08ff380bb0760da6d3b8cce37f25a23e 185 Gene3D G3DSA:3.30.1360.40 31 105 2.5E-71 T 12-10-2018 HW35_16780 08ff380bb0760da6d3b8cce37f25a23e 185 Pfam PF01765 Ribosome recycling factor 22 183 2.8E-66 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 HW35_16780 08ff380bb0760da6d3b8cce37f25a23e 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.803 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 HW35_05505 331e67f8f65cd910f6103e02f82e33a4 318 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 313 33.66 T 12-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 HW35_05505 331e67f8f65cd910f6103e02f82e33a4 318 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 8 305 5.8E-93 T 12-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 HW35_05505 331e67f8f65cd910f6103e02f82e33a4 318 PIRSF PIRSF037748 1 314 7.2E-119 T 12-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 HW35_05505 331e67f8f65cd910f6103e02f82e33a4 318 Pfam PF11858 Domain of unknown function (DUF3378) 3 70 6.5E-22 T 12-10-2018 IPR024568 Ribonuclease HIII, N-terminal HW35_05505 331e67f8f65cd910f6103e02f82e33a4 318 Gene3D G3DSA:3.30.420.10 98 317 2.8E-78 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_05505 331e67f8f65cd910f6103e02f82e33a4 318 Pfam PF01351 Ribonuclease HII 101 306 1.2E-46 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain HW35_05505 331e67f8f65cd910f6103e02f82e33a4 318 Gene3D G3DSA:3.30.310.10 1 89 1.9E-24 T 12-10-2018 IPR012295 TBP domain superfamily HW35_05505 331e67f8f65cd910f6103e02f82e33a4 318 SUPERFAMILY SSF53098 99 312 7.74E-48 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_10345 e30933b9f38322e5da6892afb55784cd 336 Gene3D G3DSA:3.30.200.20 19 107 7.2E-24 T 12-10-2018 HW35_10345 e30933b9f38322e5da6892afb55784cd 336 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 33 54 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 HW35_10345 e30933b9f38322e5da6892afb55784cd 336 Gene3D G3DSA:1.10.510.10 108 261 7.2E-24 T 12-10-2018 HW35_10345 e30933b9f38322e5da6892afb55784cd 336 SMART SM00220 27 285 1.0E-5 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HW35_10345 e30933b9f38322e5da6892afb55784cd 336 Pfam PF00069 Protein kinase domain 27 239 2.8E-13 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HW35_10345 e30933b9f38322e5da6892afb55784cd 336 SUPERFAMILY SSF56112 24 215 2.08E-23 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_10670 0db795be5bba886686d2de0a75ed7eec 199 SUPERFAMILY SSF53335 7 198 4.7E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_10670 0db795be5bba886686d2de0a75ed7eec 199 Pfam PF05175 Methyltransferase small domain 28 195 5.6E-49 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 HW35_10670 0db795be5bba886686d2de0a75ed7eec 199 Gene3D G3DSA:3.40.50.150 6 199 1.2E-46 T 12-10-2018 HW35_03430 be417461093d07bf2e6d3f7de5713035 193 Pfam PF01553 Acyltransferase 21 144 1.3E-23 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 HW35_03430 be417461093d07bf2e6d3f7de5713035 193 SUPERFAMILY SSF69593 3 191 9.94E-48 T 12-10-2018 HW35_03430 be417461093d07bf2e6d3f7de5713035 193 SMART SM00563 35 147 5.4E-35 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 HW35_08570 a9c1fe6baa63b4832bbee61b874189a1 201 SUPERFAMILY SSF52540 5 199 8.95E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_08570 a9c1fe6baa63b4832bbee61b874189a1 201 Gene3D G3DSA:3.40.50.300 1 201 1.2E-51 T 12-10-2018 HW35_08570 a9c1fe6baa63b4832bbee61b874189a1 201 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_08570 a9c1fe6baa63b4832bbee61b874189a1 201 Pfam PF00005 ABC transporter 19 152 1.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_08570 a9c1fe6baa63b4832bbee61b874189a1 201 SMART SM00382 28 198 1.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_16745 6df733d1dfa31c6cae03f641e54e8925 435 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 337 360 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 HW35_16745 6df733d1dfa31c6cae03f641e54e8925 435 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 6 434 37.004 T 12-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 HW35_16745 6df733d1dfa31c6cae03f641e54e8925 435 Pfam PF01134 Glucose inhibited division protein A 6 367 1.0E-117 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 HW35_16745 6df733d1dfa31c6cae03f641e54e8925 435 Gene3D G3DSA:3.50.50.60 3 178 2.9E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_16745 6df733d1dfa31c6cae03f641e54e8925 435 Gene3D G3DSA:3.50.50.60 288 435 2.9E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_16745 6df733d1dfa31c6cae03f641e54e8925 435 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 5 433 4.2E-238 T 12-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 HW35_16745 6df733d1dfa31c6cae03f641e54e8925 435 SUPERFAMILY SSF51905 3 366 9.72E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_11750 fc14705a0b04969db111f4dd56091644 346 Pfam PF11258 Protein of unknown function (DUF3048) N-terminal domain 53 193 1.4E-50 T 12-10-2018 IPR021416 Protein of unknown function DUF3048, N-terminal HW35_11750 fc14705a0b04969db111f4dd56091644 346 SUPERFAMILY SSF159774 49 337 2.62E-94 T 12-10-2018 IPR023158 YerB-like superfamily HW35_11750 fc14705a0b04969db111f4dd56091644 346 Gene3D G3DSA:3.50.90.10 38 344 3.8E-106 T 12-10-2018 IPR023158 YerB-like superfamily HW35_11750 fc14705a0b04969db111f4dd56091644 346 Pfam PF17479 Protein of unknown function (DUF3048) C-terminal domain 225 331 6.2E-24 T 12-10-2018 IPR035328 Protein of unknown function DUF3048, C-terminal domain HW35_09695 e37735577d701153b18fe002bd08f277 157 Pfam PF04657 Putative inner membrane exporter, YdcZ 5 138 1.1E-30 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ HW35_02735 55110f53d5ce558a5208068dfdb9ce9e 221 SMART SM00882 9 205 5.9E-60 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 HW35_02735 55110f53d5ce558a5208068dfdb9ce9e 221 Gene3D G3DSA:3.40.1080.10 5 217 4.2E-91 T 12-10-2018 HW35_02735 55110f53d5ce558a5208068dfdb9ce9e 221 SUPERFAMILY SSF100950 6 219 3.75E-69 T 12-10-2018 IPR037171 NagB/RpiA transferase-like HW35_02735 55110f53d5ce558a5208068dfdb9ce9e 221 Pfam PF01144 Coenzyme A transferase 10 205 4.0E-37 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 HW35_02735 55110f53d5ce558a5208068dfdb9ce9e 221 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 8 212 3.3E-93 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 HW35_10720 68217530b4c2b043d991d25b7ceef83e 207 Gene3D G3DSA:3.40.1370.10 3 207 4.6E-85 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 HW35_10720 68217530b4c2b043d991d25b7ceef83e 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 38.239 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10720 68217530b4c2b043d991d25b7ceef83e 207 SUPERFAMILY SSF52166 1 206 3.53E-87 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 HW35_10720 68217530b4c2b043d991d25b7ceef83e 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 7.2E-75 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 HW35_10720 68217530b4c2b043d991d25b7ceef83e 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 3.7E-84 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_03005 afa5698c60760b5220a3850cb1532dff 1226 SUPERFAMILY SSF52540 35 297 9.48E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03005 afa5698c60760b5220a3850cb1532dff 1226 SUPERFAMILY SSF52540 624 949 3.55E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03005 afa5698c60760b5220a3850cb1532dff 1226 Gene3D G3DSA:3.40.50.300 51 270 4.5E-39 T 12-10-2018 HW35_03005 afa5698c60760b5220a3850cb1532dff 1226 Pfam PF00350 Dynamin family 51 205 1.2E-26 T 12-10-2018 IPR022812 Dynamin superfamily HW35_03005 afa5698c60760b5220a3850cb1532dff 1226 Pfam PF00350 Dynamin family 648 875 1.9E-43 T 12-10-2018 IPR022812 Dynamin superfamily HW35_15465 67866ac0a9ec003277d802e626a6ac0a 140 Pfam PF13673 Acetyltransferase (GNAT) domain 30 139 6.7E-23 T 12-10-2018 IPR000182 GNAT domain HW35_15465 67866ac0a9ec003277d802e626a6ac0a 140 SUPERFAMILY SSF55729 2 140 2.74E-38 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_15465 67866ac0a9ec003277d802e626a6ac0a 140 Gene3D G3DSA:3.40.630.30 1 139 9.8E-45 T 12-10-2018 HW35_12555 116c20820f9a4d04b86955f2e7ca5919 298 SUPERFAMILY SSF51658 6 295 1.09E-64 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily HW35_12555 116c20820f9a4d04b86955f2e7ca5919 298 Pfam PF01261 Xylose isomerase-like TIM barrel 37 250 1.2E-28 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HW35_12555 116c20820f9a4d04b86955f2e7ca5919 298 Gene3D G3DSA:3.20.20.150 3 295 1.6E-88 T 12-10-2018 HW35_12555 116c20820f9a4d04b86955f2e7ca5919 298 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 6 294 1.7E-132 T 12-10-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 HW35_12555 116c20820f9a4d04b86955f2e7ca5919 298 Hamap MF_01672 Inosose dehydratase [iolE]. 2 298 57.437 T 12-10-2018 IPR023952 Inosose dehydratase GO:0019310|GO:0030145|GO:0050114 KEGG: 00562+4.2.1.44 HW35_05195 4ef6f1fd90efc6fbd9b1c0678506053c 394 TIGRFAM TIGR02907 spore_VI_D: stage VI sporulation protein D 9 388 1.4E-71 T 12-10-2018 IPR014256 Sporulation stage VI, protein D HW35_05195 4ef6f1fd90efc6fbd9b1c0678506053c 394 Gene3D G3DSA:3.10.350.10 333 394 4.6E-13 T 12-10-2018 IPR036779 LysM domain superfamily HW35_05195 4ef6f1fd90efc6fbd9b1c0678506053c 394 SUPERFAMILY SSF54106 344 388 1.29E-8 T 12-10-2018 HW35_05195 4ef6f1fd90efc6fbd9b1c0678506053c 394 SMART SM00257 344 388 2.7E-8 T 12-10-2018 IPR018392 LysM domain HW35_05195 4ef6f1fd90efc6fbd9b1c0678506053c 394 Pfam PF01476 LysM domain 346 388 9.7E-9 T 12-10-2018 IPR018392 LysM domain HW35_07510 a57157b782539ad455aca5a3c74755a7 505 Pfam PF00361 Proton-conducting membrane transporter 122 402 2.4E-69 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_07510 a57157b782539ad455aca5a3c74755a7 505 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 69 108 8.5E-7 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_07510 a57157b782539ad455aca5a3c74755a7 505 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 71 96 1.0E-12 T 12-10-2018 HW35_07510 a57157b782539ad455aca5a3c74755a7 505 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 301 313 1.0E-12 T 12-10-2018 HW35_07510 a57157b782539ad455aca5a3c74755a7 505 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 213 234 1.0E-12 T 12-10-2018 HW35_07510 a57157b782539ad455aca5a3c74755a7 505 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 235 261 1.0E-12 T 12-10-2018 HW35_13360 095022eb3f745fa1de0d4eafea3f08a2 385 SUPERFAMILY SSF53901 3 261 2.03E-83 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_13360 095022eb3f745fa1de0d4eafea3f08a2 385 ProSitePatterns PS00737 Thiolases signature 2. 330 346 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 HW35_13360 095022eb3f745fa1de0d4eafea3f08a2 385 Pfam PF02803 Thiolase, C-terminal domain 262 383 9.4E-44 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 HW35_13360 095022eb3f745fa1de0d4eafea3f08a2 385 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 382 7.2E-144 T 12-10-2018 IPR002155 Thiolase GO:0016747 HW35_13360 095022eb3f745fa1de0d4eafea3f08a2 385 SUPERFAMILY SSF53901 262 383 3.94E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_13360 095022eb3f745fa1de0d4eafea3f08a2 385 Gene3D G3DSA:3.40.47.10 6 267 9.2E-157 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_13360 095022eb3f745fa1de0d4eafea3f08a2 385 Gene3D G3DSA:3.40.47.10 127 381 9.2E-157 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_13360 095022eb3f745fa1de0d4eafea3f08a2 385 Pfam PF00108 Thiolase, N-terminal domain 4 253 2.5E-83 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 HW35_13360 095022eb3f745fa1de0d4eafea3f08a2 385 PIRSF PIRSF000429 1 385 5.3E-135 T 12-10-2018 IPR002155 Thiolase GO:0016747 HW35_12885 65edba6d70ba5d745ac519b4afd59326 235 SUPERFAMILY SSF48371 1 235 1.38E-67 T 12-10-2018 IPR016024 Armadillo-type fold HW35_12885 65edba6d70ba5d745ac519b4afd59326 235 Pfam PF08713 DNA alkylation repair enzyme 6 201 3.3E-19 T 12-10-2018 IPR014825 DNA alkylation repair enzyme HW35_00290 4c03a36eba445a658d9b9df3a4332175 274 Pfam PF00700 Bacterial flagellin C-terminal helical region 189 273 1.1E-27 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HW35_00290 4c03a36eba445a658d9b9df3a4332175 274 PRINTS PR00207 Flagellin signature 35 52 1.5E-24 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HW35_00290 4c03a36eba445a658d9b9df3a4332175 274 PRINTS PR00207 Flagellin signature 109 132 1.5E-24 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HW35_00290 4c03a36eba445a658d9b9df3a4332175 274 PRINTS PR00207 Flagellin signature 74 93 1.5E-24 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HW35_00290 4c03a36eba445a658d9b9df3a4332175 274 Gene3D G3DSA:1.10.8.410 225 274 4.2E-28 T 12-10-2018 HW35_00290 4c03a36eba445a658d9b9df3a4332175 274 Gene3D G3DSA:1.20.1330.10 48 224 8.7E-66 T 12-10-2018 HW35_00290 4c03a36eba445a658d9b9df3a4332175 274 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 9.4E-44 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HW35_00290 4c03a36eba445a658d9b9df3a4332175 274 SUPERFAMILY SSF64518 1 274 6.67E-95 T 12-10-2018 HW35_16820 0bbef762f4ce18707f326f4e34b4a742 94 Pfam PF04296 Protein of unknown function (DUF448) 10 82 1.3E-25 T 12-10-2018 IPR007393 Domain of unknown function DUF448 HW35_16820 0bbef762f4ce18707f326f4e34b4a742 94 SUPERFAMILY SSF64376 5 88 1.44E-27 T 12-10-2018 IPR035931 YlxR-like superfamily HW35_16820 0bbef762f4ce18707f326f4e34b4a742 94 Gene3D G3DSA:3.30.1230.10 1 94 2.5E-34 T 12-10-2018 IPR035931 YlxR-like superfamily HW35_01335 25f5b62b14f93fa0355ca131d5616e3d 146 Pfam PF07486 Cell Wall Hydrolase 24 133 2.3E-16 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 HW35_01335 25f5b62b14f93fa0355ca131d5616e3d 146 Gene3D G3DSA:1.10.10.2520 8 96 3.6E-11 T 12-10-2018 HW35_14585 d06da6b7b1b44990625267b6ceafdb87 290 Pfam PF12671 Putative amidase domain 131 285 9.1E-40 T 12-10-2018 IPR024301 Putative amidase domain HW35_01515 2fb1ddc22d929c6b020ed43e36965acb 277 Pfam PF13276 HTH-like domain 34 87 6.3E-14 T 12-10-2018 IPR025948 HTH-like domain HW35_01515 2fb1ddc22d929c6b020ed43e36965acb 277 Gene3D G3DSA:3.30.420.10 115 258 6.0E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_01515 2fb1ddc22d929c6b020ed43e36965acb 277 SUPERFAMILY SSF53098 119 270 9.56E-32 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_01515 2fb1ddc22d929c6b020ed43e36965acb 277 Pfam PF00665 Integrase core domain 117 228 1.0E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_01200 f17c7058b3daf0fd816ed35220d5b031 330 Pfam PF04294 VanW like protein 189 316 6.0E-45 T 12-10-2018 IPR007391 Vancomycin resistance VanW HW35_13135 222de30c910bcbb3aae02d0981cecc2d 286 Gene3D G3DSA:1.10.3720.10 45 284 4.4E-61 T 12-10-2018 IPR035906 MetI-like superfamily HW35_13135 222de30c910bcbb3aae02d0981cecc2d 286 SUPERFAMILY SSF161098 49 271 1.96E-54 T 12-10-2018 IPR035906 MetI-like superfamily HW35_13135 222de30c910bcbb3aae02d0981cecc2d 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 281 2.9E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_01670 349b68025267e8337efa9ff010dd178b 435 Gene3D G3DSA:3.20.20.140 80 377 3.2E-170 T 12-10-2018 HW35_01670 349b68025267e8337efa9ff010dd178b 435 Pfam PF01979 Amidohydrolase family 76 417 9.7E-20 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 HW35_01670 349b68025267e8337efa9ff010dd178b 435 SUPERFAMILY SSF51556 79 378 1.46E-84 T 12-10-2018 IPR032466 Metal-dependent hydrolase HW35_01670 349b68025267e8337efa9ff010dd178b 435 Gene3D G3DSA:2.30.40.10 8 415 3.2E-170 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_01670 349b68025267e8337efa9ff010dd178b 435 SUPERFAMILY SSF51338 35 419 6.83E-20 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_01670 349b68025267e8337efa9ff010dd178b 435 TIGRFAM TIGR01224 hutI: imidazolonepropionase 35 415 1.5E-145 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_01670 349b68025267e8337efa9ff010dd178b 435 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 417 42.626 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 HW35_15440 19dccb28b91d62075cfd3052dbe2e622 156 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 45 138 5.3E-7 T 12-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like HW35_05735 b6fd3fb0ade5f02ffd5c9c06af8fd718 105 Pfam PF14007 YtpI-like protein 5 89 4.4E-28 T 12-10-2018 IPR025618 YtpI-like protein HW35_14000 e29085c046fe023e200f632e1cc96474 239 PIRSF PIRSF029950 1 217 1.6E-70 T 12-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 HW35_14000 e29085c046fe023e200f632e1cc96474 239 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 6 48 1.5E-12 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal HW35_14000 e29085c046fe023e200f632e1cc96474 239 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 5 198 1.5E-46 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 HW35_14000 e29085c046fe023e200f632e1cc96474 239 TIGRFAM TIGR01876 cas_Cas5d: CRISPR-associated protein Cas5, subtype I-C/DVULG 7 205 1.5E-89 T 12-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 HW35_14000 e29085c046fe023e200f632e1cc96474 239 Gene3D G3DSA:3.30.70.2660 1 220 4.4E-95 T 12-10-2018 HW35_03520 1311330dbcd4190088b2e4fd1c0abe57 348 Pfam PF14493 Helix-turn-helix domain 253 339 2.3E-24 T 12-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 HW35_03520 1311330dbcd4190088b2e4fd1c0abe57 348 PIRSF PIRSF021350 2 347 3.4E-96 T 12-10-2018 IPR008308 Uncharacterised conserved protein UCP021350 HW35_15000 828b65f0140eb2e86f54720c5aa158e0 329 Gene3D G3DSA:3.30.390.50 243 329 3.7E-34 T 12-10-2018 HW35_15000 828b65f0140eb2e86f54720c5aa158e0 329 SUPERFAMILY SSF82649 243 329 1.15E-29 T 12-10-2018 HW35_15000 828b65f0140eb2e86f54720c5aa158e0 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 322 9.6E-134 T 12-10-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 HW35_15000 828b65f0140eb2e86f54720c5aa158e0 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 244 328 9.6E-33 T 12-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 HW35_15000 828b65f0140eb2e86f54720c5aa158e0 329 Gene3D G3DSA:3.30.930.10 3 242 1.4E-82 T 12-10-2018 HW35_15000 828b65f0140eb2e86f54720c5aa158e0 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 151 2.1E-11 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 HW35_15000 828b65f0140eb2e86f54720c5aa158e0 329 SUPERFAMILY SSF55681 2 242 1.7E-83 T 12-10-2018 HW35_14235 7546ab5cc888e318276b6e3576f97119 326 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 2 171 8.4E-26 T 12-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase HW35_01695 cf3bfdfcd6dd4d2d73f201a1cb112f22 214 Pfam PF13649 Methyltransferase domain 49 141 3.5E-17 T 12-10-2018 HW35_01695 cf3bfdfcd6dd4d2d73f201a1cb112f22 214 Gene3D G3DSA:3.40.50.150 24 214 2.8E-50 T 12-10-2018 HW35_01695 cf3bfdfcd6dd4d2d73f201a1cb112f22 214 SUPERFAMILY SSF53335 7 201 5.02E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_01695 cf3bfdfcd6dd4d2d73f201a1cb112f22 214 Hamap MF_02100 Uncharacterized methyltransferase . 2 214 42.203 T 12-10-2018 IPR023553 Uncharacterised methyltransferase, YrrT GO:0008168 HW35_01355 67d883243b0c9951e886579e882dc48c 317 Gene3D G3DSA:3.40.190.10 112 211 1.8E-111 T 12-10-2018 HW35_01355 67d883243b0c9951e886579e882dc48c 317 SUPERFAMILY SSF53850 31 266 6.7E-53 T 12-10-2018 HW35_01355 67d883243b0c9951e886579e882dc48c 317 Pfam PF13379 NMT1-like family 31 256 2.2E-17 T 12-10-2018 HW35_01355 67d883243b0c9951e886579e882dc48c 317 Gene3D G3DSA:1.10.8.450 243 275 1.8E-111 T 12-10-2018 HW35_01355 67d883243b0c9951e886579e882dc48c 317 SMART SM00062 32 248 1.8E-29 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HW35_01355 67d883243b0c9951e886579e882dc48c 317 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 33 311 9.7E-76 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 HW35_01355 67d883243b0c9951e886579e882dc48c 317 Gene3D G3DSA:3.40.190.10 33 306 1.8E-111 T 12-10-2018 HW35_03100 ef1abf71a3fc2b0eeb938a09bea199e0 420 SUPERFAMILY SSF53098 89 275 4.11E-27 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_03100 ef1abf71a3fc2b0eeb938a09bea199e0 420 Gene3D G3DSA:1.25.40.10 278 410 2.5E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HW35_03100 ef1abf71a3fc2b0eeb938a09bea199e0 420 Pfam PF13482 RNase_H superfamily 105 273 1.0E-36 T 12-10-2018 IPR038720 YprB, ribonuclease H-like domain HW35_03100 ef1abf71a3fc2b0eeb938a09bea199e0 420 SUPERFAMILY SSF81901 289 386 9.15E-7 T 12-10-2018 HW35_12615 8d82d2c0f9f46d25e74af3e25914ee9e 163 Gene3D G3DSA:1.10.287.110 104 163 4.0E-11 T 12-10-2018 IPR036869 Chaperone J-domain superfamily HW35_12615 8d82d2c0f9f46d25e74af3e25914ee9e 163 SUPERFAMILY SSF46565 113 161 1.03E-11 T 12-10-2018 IPR036869 Chaperone J-domain superfamily HW35_16775 a9421472710264246df9984daaa3ce9c 241 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 2.7E-103 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 HW35_16775 a9421472710264246df9984daaa3ce9c 241 PIRSF PIRSF005650 1 241 8.9E-99 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 HW35_16775 a9421472710264246df9984daaa3ce9c 241 Gene3D G3DSA:3.40.1160.10 1 240 7.1E-82 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_16775 a9421472710264246df9984daaa3ce9c 241 Pfam PF00696 Amino acid kinase family 7 217 3.5E-28 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 HW35_16775 a9421472710264246df9984daaa3ce9c 241 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.13 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 HW35_16775 a9421472710264246df9984daaa3ce9c 241 SUPERFAMILY SSF53633 4 238 8.51E-75 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HW35_13790 2d3579a8dfd0a0df2a1631b840dfc0f3 222 Pfam PF08713 DNA alkylation repair enzyme 27 167 6.3E-9 T 12-10-2018 IPR014825 DNA alkylation repair enzyme HW35_13790 2d3579a8dfd0a0df2a1631b840dfc0f3 222 SUPERFAMILY SSF48371 27 217 4.89E-38 T 12-10-2018 IPR016024 Armadillo-type fold HW35_04140 8c5a239b8707cecf9b8285f0e96f67ee 127 Gene3D G3DSA:3.40.250.10 31 127 2.2E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_04140 8c5a239b8707cecf9b8285f0e96f67ee 127 SUPERFAMILY SSF52821 9 120 4.45E-36 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily HW35_04140 8c5a239b8707cecf9b8285f0e96f67ee 127 SMART SM00450 30 125 3.4E-29 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_04140 8c5a239b8707cecf9b8285f0e96f67ee 127 Pfam PF00581 Rhodanese-like domain 42 120 2.1E-18 T 12-10-2018 IPR001763 Rhodanese-like domain HW35_14120 0fedd805ff83bd826a5c2915ad439ff0 250 Pfam PF01487 Type I 3-dehydroquinase 20 245 6.8E-68 T 12-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HW35_14120 0fedd805ff83bd826a5c2915ad439ff0 250 Gene3D G3DSA:3.20.20.70 1 250 1.2E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_14120 0fedd805ff83bd826a5c2915ad439ff0 250 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 18 248 37.438 T 12-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HW35_14120 0fedd805ff83bd826a5c2915ad439ff0 250 ProSitePatterns PS01028 Dehydroquinase class I active site. 115 145 - T 12-10-2018 IPR018508 3-dehydroquinate dehydratase, active site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HW35_14120 0fedd805ff83bd826a5c2915ad439ff0 250 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 18 244 3.6E-72 T 12-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HW35_14120 0fedd805ff83bd826a5c2915ad439ff0 250 SUPERFAMILY SSF51569 3 248 8.42E-77 T 12-10-2018 HW35_14710 466c6c9463e7b8a91df87f8598542b63 104 Gene3D G3DSA:3.10.450.390 17 103 1.6E-11 T 12-10-2018 HW35_14710 466c6c9463e7b8a91df87f8598542b63 104 Pfam PF13028 Protein of unknown function (DUF3889) 10 100 2.4E-19 T 12-10-2018 IPR024987 Protein of unknown function DUF3889 HW35_07125 fff70ff16faa19917d91124dffc8ee3a 118 Gene3D G3DSA:3.40.1360.20 4 118 1.6E-44 T 12-10-2018 HW35_07125 fff70ff16faa19917d91124dffc8ee3a 118 SMART SM00493 7 81 0.0037 T 12-10-2018 IPR006171 TOPRIM domain HW35_07125 fff70ff16faa19917d91124dffc8ee3a 118 SUPERFAMILY SSF110455 5 113 2.62E-34 T 12-10-2018 HW35_16380 e32c650d7979b7cdaf71f50c9c481fbf 312 Pfam PF03419 Sporulation factor SpoIIGA 2 298 1.4E-77 T 12-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 HW35_16380 e32c650d7979b7cdaf71f50c9c481fbf 312 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 2 299 7.9E-88 T 12-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 HW35_16380 e32c650d7979b7cdaf71f50c9c481fbf 312 PIRSF PIRSF018571 1 301 3.5E-81 T 12-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 HW35_14055 dc7b0f9ceebd68c64321897678c3295d 523 SUPERFAMILY SSF54862 2 487 1.67E-154 T 12-10-2018 HW35_14055 dc7b0f9ceebd68c64321897678c3295d 523 Gene3D G3DSA:1.10.3650.10 356 434 8.3E-25 T 12-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 HW35_14055 dc7b0f9ceebd68c64321897678c3295d 523 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 356 435 6.0E-26 T 12-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 HW35_14055 dc7b0f9ceebd68c64321897678c3295d 523 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 487 9.6E-247 T 12-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 HW35_14055 dc7b0f9ceebd68c64321897678c3295d 523 Gene3D G3DSA:3.30.70.20 1 296 6.8E-97 T 12-10-2018 HW35_14055 dc7b0f9ceebd68c64321897678c3295d 523 Pfam PF13247 4Fe-4S dicluster domain 173 269 4.0E-37 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HW35_06650 503b1160fca6a99a58d93f1994382f74 349 Pfam PF10282 Lactonase, 7-bladed beta-propeller 8 346 3.9E-129 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller HW35_06650 503b1160fca6a99a58d93f1994382f74 349 Gene3D G3DSA:2.130.10.10 6 349 2.1E-127 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 HW35_06650 503b1160fca6a99a58d93f1994382f74 349 SUPERFAMILY SSF51004 12 348 6.02E-49 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily HW35_06775 9753563e1df6637f5ea73133247978b8 133 Pfam PF08868 YugN-like family 3 131 5.5E-55 T 12-10-2018 IPR014967 Uncharacterised protein family, YugN-like HW35_06775 9753563e1df6637f5ea73133247978b8 133 SUPERFAMILY SSF160755 1 132 1.7E-38 T 12-10-2018 IPR036491 YugN-like superfamily HW35_06775 9753563e1df6637f5ea73133247978b8 133 Gene3D G3DSA:3.30.310.100 4 112 6.9E-30 T 12-10-2018 IPR036491 YugN-like superfamily HW35_12115 5d0cef233de2a3bfa8cac8d7e7299347 340 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 329 5.1E-45 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 HW35_14775 9782231819244bead361b25757d2e9f2 182 Gene3D G3DSA:3.40.630.30 1 176 4.8E-47 T 12-10-2018 HW35_14775 9782231819244bead361b25757d2e9f2 182 SUPERFAMILY SSF55729 7 174 1.22E-43 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_14775 9782231819244bead361b25757d2e9f2 182 Pfam PF13302 Acetyltransferase (GNAT) domain 11 150 3.6E-22 T 12-10-2018 IPR000182 GNAT domain HW35_14995 d4146bc50a5b5224abdcc271ccd728bf 244 Gene3D G3DSA:3.60.15.10 1 242 1.2E-83 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_14995 d4146bc50a5b5224abdcc271ccd728bf 244 SUPERFAMILY SSF56281 1 242 9.7E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_14995 d4146bc50a5b5224abdcc271ccd728bf 244 SMART SM00849 18 211 4.7E-10 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_14995 d4146bc50a5b5224abdcc271ccd728bf 244 Pfam PF12706 Beta-lactamase superfamily domain 31 211 1.3E-19 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_02375 d61b4fc953a58892ad3136753ae94b8a 336 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 298 3.3E-27 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 HW35_05605 8a7005bde9bdb4775379d4b73d4d4447 124 Gene3D G3DSA:3.30.160.750 63 123 1.1E-18 T 12-10-2018 HW35_05605 8a7005bde9bdb4775379d4b73d4d4447 124 Pfam PF02675 S-adenosylmethionine decarboxylase 7 112 7.3E-37 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HW35_05605 8a7005bde9bdb4775379d4b73d4d4447 124 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 112 3.2E-42 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HW35_05605 8a7005bde9bdb4775379d4b73d4d4447 124 Gene3D G3DSA:3.30.360.110 1 62 1.9E-26 T 12-10-2018 HW35_05605 8a7005bde9bdb4775379d4b73d4d4447 124 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 116 32.044 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HW35_05605 8a7005bde9bdb4775379d4b73d4d4447 124 SUPERFAMILY SSF56276 2 113 5.3E-41 T 12-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 HW35_07995 415a8e283435813d7adff27cabb62b28 486 Pfam PF01943 Polysaccharide biosynthesis protein 5 270 6.9E-23 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HW35_07995 415a8e283435813d7adff27cabb62b28 486 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 325 466 5.9E-11 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HW35_04105 2d7522af7261abc7a43ba28be8a89840 762 Gene3D G3DSA:3.20.20.210 389 756 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HW35_04105 2d7522af7261abc7a43ba28be8a89840 762 SUPERFAMILY SSF51726 396 758 4.06E-114 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HW35_04105 2d7522af7261abc7a43ba28be8a89840 762 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 758 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HW35_04105 2d7522af7261abc7a43ba28be8a89840 762 Gene3D G3DSA:3.20.20.210 7 524 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HW35_04105 2d7522af7261abc7a43ba28be8a89840 762 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 431 753 1.1E-146 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HW35_04105 2d7522af7261abc7a43ba28be8a89840 762 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 758 33.084 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HW35_04105 2d7522af7261abc7a43ba28be8a89840 762 PIRSF PIRSF000382 2 762 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HW35_04105 2d7522af7261abc7a43ba28be8a89840 762 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 313 1.3E-108 T 12-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HW35_04105 2d7522af7261abc7a43ba28be8a89840 762 SUPERFAMILY SSF51726 5 390 3.92E-91 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HW35_03965 1a79c98947b3fe48d827b397fd2ca87d 77 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 5 49 7.0E-12 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HW35_03965 1a79c98947b3fe48d827b397fd2ca87d 77 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 8 68 15.405 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HW35_03965 1a79c98947b3fe48d827b397fd2ca87d 77 PIRSF PIRSF006488 1 77 2.9E-21 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HW35_03965 1a79c98947b3fe48d827b397fd2ca87d 77 Gene3D G3DSA:1.10.287.1040 2 76 2.6E-23 T 12-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 HW35_03965 1a79c98947b3fe48d827b397fd2ca87d 77 Pfam PF02609 Exonuclease VII small subunit 9 59 4.0E-22 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HW35_03965 1a79c98947b3fe48d827b397fd2ca87d 77 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 8 63 6.2E-24 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HW35_03965 1a79c98947b3fe48d827b397fd2ca87d 77 SUPERFAMILY SSF116842 3 68 5.23E-22 T 12-10-2018 HW35_07210 c54d8256f1a4d9c2ed4022eeae7750c3 260 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 255 16.982 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HW35_07210 c54d8256f1a4d9c2ed4022eeae7750c3 260 Pfam PF02673 Bacitracin resistance protein BacA 7 249 6.9E-76 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HW35_06155 f51d1df5d6e73d1ad115310afbed87ee 170 SUPERFAMILY SSF51161 2 168 1.66E-48 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily HW35_06155 f51d1df5d6e73d1ad115310afbed87ee 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 10 44 1.3E-4 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_06155 f51d1df5d6e73d1ad115310afbed87ee 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 120 2.9E-7 T 12-10-2018 IPR001451 Hexapeptide repeat HW35_06155 f51d1df5d6e73d1ad115310afbed87ee 170 Gene3D G3DSA:2.160.10.10 1 170 1.3E-75 T 12-10-2018 HW35_01090 f0e22c4fceb4a2da6cc90a59afa01727 368 Pfam PF00149 Calcineurin-like phosphoesterase 148 310 8.8E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 HW35_01090 f0e22c4fceb4a2da6cc90a59afa01727 368 Gene3D G3DSA:3.60.21.10 145 333 4.9E-24 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like HW35_01090 f0e22c4fceb4a2da6cc90a59afa01727 368 SUPERFAMILY SSF56300 144 366 4.98E-33 T 12-10-2018 HW35_05290 edb633be98d210d0af428f9a0df0d328 293 SMART SM00382 29 207 9.5E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_05290 edb633be98d210d0af428f9a0df0d328 293 Pfam PF00005 ABC transporter 20 159 2.1E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_05290 edb633be98d210d0af428f9a0df0d328 293 Pfam PF13732 Domain of unknown function (DUF4162) 212 289 6.2E-9 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 HW35_05290 edb633be98d210d0af428f9a0df0d328 293 SUPERFAMILY SSF52540 4 219 4.26E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_05290 edb633be98d210d0af428f9a0df0d328 293 Gene3D G3DSA:3.40.50.300 1 230 1.8E-60 T 12-10-2018 HW35_05290 edb633be98d210d0af428f9a0df0d328 293 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_09510 e6c615c1a0ce5a9d73535e6eb91aa758 213 Pfam PF08713 DNA alkylation repair enzyme 2 211 1.9E-63 T 12-10-2018 IPR014825 DNA alkylation repair enzyme HW35_09510 e6c615c1a0ce5a9d73535e6eb91aa758 213 SUPERFAMILY SSF48371 3 211 2.3E-52 T 12-10-2018 IPR016024 Armadillo-type fold HW35_09510 e6c615c1a0ce5a9d73535e6eb91aa758 213 Gene3D G3DSA:1.25.10.90 1 213 9.6E-81 T 12-10-2018 HW35_05025 7de500e508606c9b163df84ad7d0c11a 149 SUPERFAMILY SSF55021 73 145 2.39E-10 T 12-10-2018 HW35_05025 7de500e508606c9b163df84ad7d0c11a 149 Hamap MF_00707 UPF0735 ACT domain-containing protein . 4 148 32.5 T 12-10-2018 IPR008310 UPF0735 ACT domain-containing protein HW35_05025 7de500e508606c9b163df84ad7d0c11a 149 Pfam PF01842 ACT domain 72 137 4.0E-7 T 12-10-2018 IPR002912 ACT domain HW35_05025 7de500e508606c9b163df84ad7d0c11a 149 PIRSF PIRSF025624 1 148 2.4E-61 T 12-10-2018 IPR008310 UPF0735 ACT domain-containing protein HW35_05025 7de500e508606c9b163df84ad7d0c11a 149 Gene3D G3DSA:3.30.70.260 71 147 2.4E-6 T 12-10-2018 HW35_07750 e5731497d8c6fcbf062589cfd2c0ad4b 274 SUPERFAMILY SSF161098 3 274 2.34E-72 T 12-10-2018 IPR035906 MetI-like superfamily HW35_07750 e5731497d8c6fcbf062589cfd2c0ad4b 274 Gene3D G3DSA:1.10.3720.10 1 266 6.8E-64 T 12-10-2018 IPR035906 MetI-like superfamily HW35_07750 e5731497d8c6fcbf062589cfd2c0ad4b 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 261 2.3E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_10250 8162d8b6a531639c82e588c1a72d5f96 124 Gene3D G3DSA:3.30.1330.40 1 124 8.5E-57 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 HW35_10250 8162d8b6a531639c82e588c1a72d5f96 124 SUPERFAMILY SSF55298 2 123 2.2E-49 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 HW35_10250 8162d8b6a531639c82e588c1a72d5f96 124 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 1 122 6.6E-56 T 12-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 HW35_10250 8162d8b6a531639c82e588c1a72d5f96 124 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 99 117 - T 12-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 HW35_10250 8162d8b6a531639c82e588c1a72d5f96 124 Pfam PF01042 Endoribonuclease L-PSP 7 122 2.3E-47 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 HW35_12920 b695667c7b65ebbb90906a04828e975f 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 1.4E-14 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HW35_12920 b695667c7b65ebbb90906a04828e975f 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.4E-14 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HW35_12920 b695667c7b65ebbb90906a04828e975f 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.4E-14 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HW35_12920 b695667c7b65ebbb90906a04828e975f 446 Pfam PF00209 Sodium:neurotransmitter symporter family 151 442 2.8E-27 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HW35_12920 b695667c7b65ebbb90906a04828e975f 446 Pfam PF00209 Sodium:neurotransmitter symporter family 4 122 4.5E-28 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HW35_12920 b695667c7b65ebbb90906a04828e975f 446 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HW35_12920 b695667c7b65ebbb90906a04828e975f 446 SUPERFAMILY SSF161070 4 444 3.14E-134 T 12-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 HW35_12685 0c82ae42d963d1f56b4fc18b3505c4a7 299 Pfam PF11185 Protein of unknown function (DUF2971) 123 217 2.7E-10 T 12-10-2018 IPR021352 Protein of unknown function DUF2971 HW35_12560 d13e0d7f4a3b9e550444d3f0867396a4 285 PIRSF PIRSF001359 1 278 5.8E-78 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HW35_12560 d13e0d7f4a3b9e550444d3f0867396a4 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 277 3.1E-93 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HW35_12560 d13e0d7f4a3b9e550444d3f0867396a4 285 SUPERFAMILY SSF51569 2 277 4.25E-86 T 12-10-2018 HW35_12560 d13e0d7f4a3b9e550444d3f0867396a4 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 277 2.5E-77 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HW35_12560 d13e0d7f4a3b9e550444d3f0867396a4 285 Gene3D G3DSA:3.20.20.70 2 284 2.1E-94 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_17235 3340bbdd0f03a9b56feeef2d88d0db5a 583 SMART SM00382 362 554 4.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_17235 3340bbdd0f03a9b56feeef2d88d0db5a 583 Gene3D G3DSA:3.40.50.300 332 580 2.0E-80 T 12-10-2018 HW35_17235 3340bbdd0f03a9b56feeef2d88d0db5a 583 SUPERFAMILY SSF90123 7 317 2.09E-73 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_17235 3340bbdd0f03a9b56feeef2d88d0db5a 583 Pfam PF00005 ABC transporter 353 500 5.1E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_17235 3340bbdd0f03a9b56feeef2d88d0db5a 583 Gene3D G3DSA:1.20.1560.10 5 319 1.1E-79 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_17235 3340bbdd0f03a9b56feeef2d88d0db5a 583 SUPERFAMILY SSF52540 332 572 2.44E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17235 3340bbdd0f03a9b56feeef2d88d0db5a 583 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_17235 3340bbdd0f03a9b56feeef2d88d0db5a 583 Pfam PF00664 ABC transporter transmembrane region 21 291 2.8E-47 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 HW35_13020 b6ffc179c3888ddca23394ceb4e6fab4 182 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 9 156 2.4E-51 T 12-10-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 HW35_13020 b6ffc179c3888ddca23394ceb4e6fab4 182 SUPERFAMILY SSF51182 8 174 1.67E-52 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily HW35_13020 b6ffc179c3888ddca23394ceb4e6fab4 182 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 11 169 3.1E-74 T 12-10-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 HW35_13020 b6ffc179c3888ddca23394ceb4e6fab4 182 Gene3D G3DSA:2.60.120.10 8 180 4.6E-67 T 12-10-2018 IPR014710 RmlC-like jelly roll fold HW35_13020 b6ffc179c3888ddca23394ceb4e6fab4 182 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 7 175 34.693 T 12-10-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 HW35_05750 31f6f58fd3b62e751efd7541861d6042 226 SUPERFAMILY SSF56281 1 219 5.63E-39 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_05750 31f6f58fd3b62e751efd7541861d6042 226 Gene3D G3DSA:3.60.15.10 1 226 1.8E-76 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_05750 31f6f58fd3b62e751efd7541861d6042 226 Pfam PF13483 Beta-lactamase superfamily domain 2 192 1.1E-26 T 12-10-2018 HW35_05750 31f6f58fd3b62e751efd7541861d6042 226 SMART SM00849 7 192 2.7E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_05750 31f6f58fd3b62e751efd7541861d6042 226 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 226 39.281 T 12-10-2018 IPR022877 Protein of unknown funcion UPF0173 HW35_08470 00899f7bafb9a815ca7dc4c0a7e6fcd9 578 Pfam PF03239 Iron permease FTR1 family 326 525 9.5E-22 T 12-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 HW35_03320 616250908e185fae20a0e28d691b65fd 368 Gene3D G3DSA:3.30.70.260 297 361 3.3E-5 T 12-10-2018 HW35_03320 616250908e185fae20a0e28d691b65fd 368 Pfam PF02153 Prephenate dehydrogenase 17 275 2.0E-78 T 12-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 HW35_03320 616250908e185fae20a0e28d691b65fd 368 SUPERFAMILY SSF51735 4 171 4.52E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_03320 616250908e185fae20a0e28d691b65fd 368 Gene3D G3DSA:1.10.3660.10 182 296 4.2E-35 T 12-10-2018 HW35_03320 616250908e185fae20a0e28d691b65fd 368 SUPERFAMILY SSF55021 291 352 2.96E-7 T 12-10-2018 HW35_03320 616250908e185fae20a0e28d691b65fd 368 Gene3D G3DSA:3.40.50.720 2 180 1.6E-49 T 12-10-2018 HW35_03320 616250908e185fae20a0e28d691b65fd 368 SUPERFAMILY SSF48179 175 284 1.11E-33 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HW35_08745 8ebe83943ee5596d0d6fb5c78b3311c5 186 SUPERFAMILY SSF48295 36 118 1.73E-14 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HW35_08745 8ebe83943ee5596d0d6fb5c78b3311c5 186 Pfam PF13518 Helix-turn-helix domain 66 118 5.2E-6 T 12-10-2018 HW35_04440 8ebe83943ee5596d0d6fb5c78b3311c5 186 SUPERFAMILY SSF48295 36 118 1.73E-14 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HW35_04440 8ebe83943ee5596d0d6fb5c78b3311c5 186 Pfam PF13518 Helix-turn-helix domain 66 118 5.2E-6 T 12-10-2018 HW35_08545 02bc3c6afe074d479ac44b20e605f669 419 Pfam PF03611 PTS system sugar-specific permease component 8 404 5.4E-149 T 12-10-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 HW35_09965 a6e2a1088d7ff67f09b76556b23d2a9c 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 2 26 6.0E-7 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09965 a6e2a1088d7ff67f09b76556b23d2a9c 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.739 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09965 a6e2a1088d7ff67f09b76556b23d2a9c 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 12-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_09965 a6e2a1088d7ff67f09b76556b23d2a9c 44 Pfam PF00468 Ribosomal protein L34 1 44 1.8E-23 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_09965 a6e2a1088d7ff67f09b76556b23d2a9c 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 2.4E-20 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_07130 2e5816d9f7d44144d02f8e64d85ad866 127 SUPERFAMILY SSF51230 3 126 1.09E-47 T 12-10-2018 IPR011053 Single hybrid motif HW35_07130 2e5816d9f7d44144d02f8e64d85ad866 127 Pfam PF01597 Glycine cleavage H-protein 7 126 2.8E-50 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate HW35_07130 2e5816d9f7d44144d02f8e64d85ad866 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 41.186 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 HW35_07130 2e5816d9f7d44144d02f8e64d85ad866 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 127 1.2E-56 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 HW35_07130 2e5816d9f7d44144d02f8e64d85ad866 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 HW35_07130 2e5816d9f7d44144d02f8e64d85ad866 127 Gene3D G3DSA:2.40.50.100 1 127 2.5E-54 T 12-10-2018 HW35_08205 5d9707d2c64989e0bee7d776b11fb3e7 167 Gene3D G3DSA:1.10.10.10 6 52 4.8E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_08205 5d9707d2c64989e0bee7d776b11fb3e7 167 Pfam PF01037 Lrp/AsnC ligand binding domain 73 144 2.1E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HW35_08205 5d9707d2c64989e0bee7d776b11fb3e7 167 SMART SM00344 8 114 1.9E-7 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 HW35_08205 5d9707d2c64989e0bee7d776b11fb3e7 167 SUPERFAMILY SSF46785 4 61 4.17E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_08205 5d9707d2c64989e0bee7d776b11fb3e7 167 Pfam PF01047 MarR family 3 53 1.4E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_08205 5d9707d2c64989e0bee7d776b11fb3e7 167 Gene3D G3DSA:3.30.70.920 55 153 6.0E-21 T 12-10-2018 HW35_08205 5d9707d2c64989e0bee7d776b11fb3e7 167 SUPERFAMILY SSF54909 66 147 4.02E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel HW35_15985 9e40f4ca13d61415056ee1add6aa94d5 279 Gene3D G3DSA:1.20.1260.120 8 278 7.1E-116 T 12-10-2018 HW35_15985 9e40f4ca13d61415056ee1add6aa94d5 279 Pfam PF11155 Domain of unknown function (DUF2935) 22 136 9.4E-32 T 12-10-2018 IPR021328 Protein of unknown function DUF2935 HW35_15985 9e40f4ca13d61415056ee1add6aa94d5 279 Pfam PF11155 Domain of unknown function (DUF2935) 151 267 1.5E-30 T 12-10-2018 IPR021328 Protein of unknown function DUF2935 HW35_15985 9e40f4ca13d61415056ee1add6aa94d5 279 SUPERFAMILY SSF158430 15 142 4.84E-38 T 12-10-2018 HW35_15985 9e40f4ca13d61415056ee1add6aa94d5 279 SUPERFAMILY SSF158430 148 271 1.01E-38 T 12-10-2018 HW35_12745 4626fb10fa29ed2fcdb18f942d84993f 218 PIRSF PIRSF001111 1 218 9.6E-107 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 HW35_12745 4626fb10fa29ed2fcdb18f942d84993f 218 SUPERFAMILY SSF52499 1 210 3.01E-61 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 HW35_12745 4626fb10fa29ed2fcdb18f942d84993f 218 Gene3D G3DSA:3.40.50.850 1 211 1.0E-75 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 HW35_12745 4626fb10fa29ed2fcdb18f942d84993f 218 Pfam PF00857 Isochorismatase family 32 203 3.1E-38 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 HW35_12745 4626fb10fa29ed2fcdb18f942d84993f 218 PRINTS PR01398 Isochorismatase signature 2 14 2.1E-47 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 HW35_12745 4626fb10fa29ed2fcdb18f942d84993f 218 PRINTS PR01398 Isochorismatase signature 168 186 2.1E-47 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 HW35_12745 4626fb10fa29ed2fcdb18f942d84993f 218 PRINTS PR01398 Isochorismatase signature 80 99 2.1E-47 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 HW35_12745 4626fb10fa29ed2fcdb18f942d84993f 218 PRINTS PR01398 Isochorismatase signature 63 80 2.1E-47 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 HW35_12745 4626fb10fa29ed2fcdb18f942d84993f 218 PRINTS PR01398 Isochorismatase signature 186 203 2.1E-47 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 HW35_12745 4626fb10fa29ed2fcdb18f942d84993f 218 PRINTS PR01398 Isochorismatase signature 112 134 2.1E-47 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 HW35_01805 8bdd6948db25cf91a665c9406cf8affe 487 SUPERFAMILY SSF51556 60 378 5.38E-64 T 12-10-2018 IPR032466 Metal-dependent hydrolase HW35_01805 8bdd6948db25cf91a665c9406cf8affe 487 Gene3D G3DSA:2.30.40.10 9 434 3.4E-118 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_01805 8bdd6948db25cf91a665c9406cf8affe 487 Pfam PF01979 Amidohydrolase family 57 428 4.9E-48 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 HW35_01805 8bdd6948db25cf91a665c9406cf8affe 487 Gene3D G3DSA:3.20.20.140 62 377 3.4E-118 T 12-10-2018 HW35_01805 8bdd6948db25cf91a665c9406cf8affe 487 SUPERFAMILY SSF51338 1 454 1.13E-28 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HW35_13630 7d25c5cda83c086d1a69cc4eb9df755e 203 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 3 195 4.2E-42 T 12-10-2018 IPR006214 Bax inhibitor 1-related HW35_13630 7d25c5cda83c086d1a69cc4eb9df755e 203 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 15 32 - T 12-10-2018 IPR000540 Flagellar motor protein MotA, conserved site HW35_07310 8fb61f14681c93dfa42c265eebddec92 375 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 208 360 5.3E-22 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HW35_07310 8fb61f14681c93dfa42c265eebddec92 375 Gene3D G3DSA:3.30.300.210 224 362 3.1E-16 T 12-10-2018 IPR038501 Spore germination GerAC superfamily HW35_07310 8fb61f14681c93dfa42c265eebddec92 375 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 1 361 7.6E-66 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HW35_04555 1aa8f99aec7ec2c0b577d22c59f6a048 379 Pfam PF04055 Radical SAM superfamily 7 176 4.3E-24 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_04555 1aa8f99aec7ec2c0b577d22c59f6a048 379 SMART SM00729 2 222 6.5E-61 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HW35_04555 1aa8f99aec7ec2c0b577d22c59f6a048 379 Gene3D G3DSA:3.80.30.20 3 301 3.1E-105 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HW35_04555 1aa8f99aec7ec2c0b577d22c59f6a048 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 366 8.0E-134 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 HW35_04555 1aa8f99aec7ec2c0b577d22c59f6a048 379 Pfam PF06969 HemN C-terminal domain 302 364 1.8E-12 T 12-10-2018 IPR010723 HemN, C-terminal HW35_04555 1aa8f99aec7ec2c0b577d22c59f6a048 379 SUPERFAMILY SSF102114 5 376 7.85E-123 T 12-10-2018 HW35_06070 40263f1905c904fa15e13bb165fafb05 293 Pfam PF13276 HTH-like domain 53 110 2.0E-21 T 12-10-2018 IPR025948 HTH-like domain HW35_06070 40263f1905c904fa15e13bb165fafb05 293 SUPERFAMILY SSF53098 127 287 1.64E-34 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_06070 40263f1905c904fa15e13bb165fafb05 293 Gene3D G3DSA:3.30.420.10 128 288 2.0E-13 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_06070 40263f1905c904fa15e13bb165fafb05 293 Pfam PF00665 Integrase core domain 133 248 2.0E-22 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_17170 c7f4bbfc55ce3336b0d3db4bc846b66a 133 Pfam PF13411 MerR HTH family regulatory protein 13 78 6.3E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_17170 c7f4bbfc55ce3336b0d3db4bc846b66a 133 SUPERFAMILY SSF46955 13 112 2.98E-21 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily HW35_17170 c7f4bbfc55ce3336b0d3db4bc846b66a 133 SMART SM00422 13 81 2.3E-26 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_17170 c7f4bbfc55ce3336b0d3db4bc846b66a 133 Gene3D G3DSA:1.10.1660.10 3 85 6.6E-26 T 12-10-2018 HW35_17170 c7f4bbfc55ce3336b0d3db4bc846b66a 133 ProSitePatterns PS00552 MerR-type HTH domain signature. 16 38 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_16405 76108dea32c3278d4cfdcacc62287970 272 SUPERFAMILY SSF64438 14 270 1.67E-77 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic HW35_16405 76108dea32c3278d4cfdcacc62287970 272 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 34 268 5.3E-55 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase HW35_16405 76108dea32c3278d4cfdcacc62287970 272 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 29 267 5.6E-69 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase HW35_16405 76108dea32c3278d4cfdcacc62287970 272 Gene3D G3DSA:3.60.140.10 2 272 2.5E-87 T 12-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily HW35_03090 8c8222c367d98aa6a0e34ab747cc5c54 130 ProDom PD057197 SPORE COAT CAPSID D INNER D COTD SPORULATION 9 71 4.0E-10 T 12-10-2018 IPR020108 Spore coat protein CotD HW35_03090 8c8222c367d98aa6a0e34ab747cc5c54 130 Pfam PF11122 Inner spore coat protein D 9 111 2.5E-17 T 12-10-2018 IPR020108 Spore coat protein CotD HW35_14985 d4f79f66a13e5afdabdb7786e0f1dde5 475 Gene3D G3DSA:1.10.3110.10 110 203 5.0E-152 T 12-10-2018 HW35_14985 d4f79f66a13e5afdabdb7786e0f1dde5 475 Gene3D G3DSA:3.90.660.20 44 415 5.0E-152 T 12-10-2018 HW35_14985 d4f79f66a13e5afdabdb7786e0f1dde5 475 Gene3D G3DSA:3.50.50.60 9 457 5.0E-152 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_14985 d4f79f66a13e5afdabdb7786e0f1dde5 475 Pfam PF01593 Flavin containing amine oxidoreductase 15 465 6.9E-67 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 HW35_14985 d4f79f66a13e5afdabdb7786e0f1dde5 475 SUPERFAMILY SSF54373 309 416 1.18E-32 T 12-10-2018 HW35_14985 d4f79f66a13e5afdabdb7786e0f1dde5 475 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 5 470 8.9E-136 T 12-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 HW35_14985 d4f79f66a13e5afdabdb7786e0f1dde5 475 SUPERFAMILY SSF51905 7 466 2.59E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_02990 6dc04d006036df58c6c2a3a8eb15c672 46 TIGRFAM TIGR03093 SASP_sspL: small, acid-soluble spore protein L 9 45 7.1E-20 T 12-10-2018 IPR017526 Small acid-soluble spore protein, SspL HW35_09415 3b4b7387b756471dd60fcc881442318d 101 ProDom PD705231 YWDI GROUP-SPECIFIC 1 101 7.0E-6 T 12-10-2018 IPR035218 Protein of unknown function DUF5327 HW35_09415 3b4b7387b756471dd60fcc881442318d 101 Pfam PF17261 Family of unknown function (DUF5327) 2 101 8.7E-29 T 12-10-2018 IPR035218 Protein of unknown function DUF5327 HW35_04040 cad04e4da27e84f86f20aafeb52c982b 305 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 28 292 4.8E-121 T 12-10-2018 IPR014217 Sporulation stage III, protein AA HW35_04040 cad04e4da27e84f86f20aafeb52c982b 305 SUPERFAMILY SSF52540 41 260 3.97E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_04040 cad04e4da27e84f86f20aafeb52c982b 305 Gene3D G3DSA:3.40.50.300 130 277 6.1E-23 T 12-10-2018 HW35_04040 cad04e4da27e84f86f20aafeb52c982b 305 SMART SM00382 135 278 2.5E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_01535 9a1ec5ad0aa72660880bd9635f7f6347 92 Pfam PF12650 Domain of unknown function (DUF3784) 6 89 1.4E-10 T 12-10-2018 IPR017259 Uncharacterised conserved protein UCP037672 HW35_16690 849536c6b135603f37394e5483b3ee3d 128 Pfam PF11068 YlqD protein 1 128 5.3E-36 T 12-10-2018 IPR021297 YlqD protein HW35_17350 977882ae457396d2bc420735f8f0c37c 326 Gene3D G3DSA:3.20.20.70 8 324 1.6E-62 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_17350 977882ae457396d2bc420735f8f0c37c 326 SUPERFAMILY SSF51412 9 292 2.01E-60 T 12-10-2018 HW35_17350 977882ae457396d2bc420735f8f0c37c 326 Pfam PF03060 Nitronate monooxygenase 12 243 8.8E-21 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 HW35_02855 8c663b418d807ad78555a6426a0fcb8f 232 SUPERFAMILY SSF55486 50 231 5.86E-30 T 12-10-2018 HW35_02855 8c663b418d807ad78555a6426a0fcb8f 232 Gene3D G3DSA:3.40.390.10 127 231 3.3E-14 T 12-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 HW35_14905 f92eccd722074b32682bd6c4a69f093e 30 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 4 29 2.7E-15 T 12-10-2018 IPR010070 Sporulation protein YjcZ-like HW35_14905 f92eccd722074b32682bd6c4a69f093e 30 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 6 29 2.0E-14 T 12-10-2018 IPR010070 Sporulation protein YjcZ-like HW35_13000 154d31a24f7ca713f7e3a07319d8015e 206 SUPERFAMILY SSF46785 133 203 1.09E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13000 154d31a24f7ca713f7e3a07319d8015e 206 Pfam PF13545 Crp-like helix-turn-helix domain 135 200 3.1E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_13000 154d31a24f7ca713f7e3a07319d8015e 206 SMART SM00100 1 116 0.0084 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain HW35_13000 154d31a24f7ca713f7e3a07319d8015e 206 Pfam PF00027 Cyclic nucleotide-binding domain 19 102 2.2E-12 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain HW35_13000 154d31a24f7ca713f7e3a07319d8015e 206 Gene3D G3DSA:2.60.120.1460 5 203 1.0E-35 T 12-10-2018 HW35_13000 154d31a24f7ca713f7e3a07319d8015e 206 SUPERFAMILY SSF51206 8 126 3.93E-19 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like HW35_13000 154d31a24f7ca713f7e3a07319d8015e 206 SMART SM00419 147 194 4.5E-5 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HW35_05370 3ee24004eacbc3a334590bcf5c4d1df8 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 5.7E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_05370 3ee24004eacbc3a334590bcf5c4d1df8 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 5.7E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_05370 3ee24004eacbc3a334590bcf5c4d1df8 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 5.7E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_05370 3ee24004eacbc3a334590bcf5c4d1df8 149 SMART SM00347 34 134 2.4E-26 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_05370 3ee24004eacbc3a334590bcf5c4d1df8 149 SUPERFAMILY SSF46785 20 148 6.12E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_05370 3ee24004eacbc3a334590bcf5c4d1df8 149 Gene3D G3DSA:1.10.10.10 6 148 2.3E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_05370 3ee24004eacbc3a334590bcf5c4d1df8 149 Pfam PF01047 MarR family 41 99 3.7E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HW35_00790 e3f3162a4d9e4735768c3c2e19d40ed3 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 383 402 1.6E-7 T 12-10-2018 HW35_00790 e3f3162a4d9e4735768c3c2e19d40ed3 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 1.6E-7 T 12-10-2018 HW35_00790 e3f3162a4d9e4735768c3c2e19d40ed3 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 216 234 1.6E-7 T 12-10-2018 HW35_00790 e3f3162a4d9e4735768c3c2e19d40ed3 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 130 154 1.6E-7 T 12-10-2018 HW35_00790 e3f3162a4d9e4735768c3c2e19d40ed3 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 100 120 1.6E-7 T 12-10-2018 HW35_00790 e3f3162a4d9e4735768c3c2e19d40ed3 455 Gene3D G3DSA:1.20.1720.10 8 232 5.7E-49 T 12-10-2018 HW35_00790 e3f3162a4d9e4735768c3c2e19d40ed3 455 SUPERFAMILY SSF103473 4 436 9.81E-76 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_00790 e3f3162a4d9e4735768c3c2e19d40ed3 455 Pfam PF07690 Major Facilitator Superfamily 12 300 2.9E-39 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_00790 e3f3162a4d9e4735768c3c2e19d40ed3 455 Gene3D G3DSA:1.20.1250.20 242 443 5.3E-27 T 12-10-2018 HW35_16120 07220c1b77670b3486f19015d1518fd8 154 Gene3D G3DSA:1.20.120.80 1 138 4.4E-6 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_16120 07220c1b77670b3486f19015d1518fd8 154 Pfam PF04238 Protein of unknown function (DUF420) 7 135 2.3E-38 T 12-10-2018 IPR007352 Protein of unknown function DUF420 HW35_12950 0197e9ed42901f6a54f180fd74349eef 152 Pfam PF11518 Protein of unknown function (DUF3221) 2 89 3.0E-12 T 12-10-2018 IPR021598 Protein of unknown function DUF3221 HW35_05320 7bd42e93f0b8f7db7a83cf337c54026f 339 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 8 337 8.5E-106 T 12-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 HW35_05320 7bd42e93f0b8f7db7a83cf337c54026f 339 PIRSF PIRSF012608 1 339 2.3E-108 T 12-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 HW35_15375 b506c989f472e7997fd8829fde47af88 196 Pfam PF01928 CYTH domain 4 186 1.0E-31 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 HW35_15375 b506c989f472e7997fd8829fde47af88 196 Gene3D G3DSA:2.40.320.10 1 192 2.6E-54 T 12-10-2018 HW35_15375 b506c989f472e7997fd8829fde47af88 196 PIRSF PIRSF012526 1 193 6.1E-69 T 12-10-2018 IPR009195 Uncharacterised protein family YjbK HW35_15375 b506c989f472e7997fd8829fde47af88 196 SUPERFAMILY SSF55154 4 188 1.21E-28 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 HW35_15375 b506c989f472e7997fd8829fde47af88 196 SMART SM01118 4 189 2.1E-20 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 HW35_00600 f2c09a687f7e4a1aa5e60f4181e81ffe 277 Pfam PF00665 Integrase core domain 115 229 2.4E-26 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_00600 f2c09a687f7e4a1aa5e60f4181e81ffe 277 SUPERFAMILY SSF53098 108 272 1.14E-33 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_00600 f2c09a687f7e4a1aa5e60f4181e81ffe 277 Gene3D G3DSA:3.30.420.10 112 269 9.3E-14 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_00600 f2c09a687f7e4a1aa5e60f4181e81ffe 277 Pfam PF13276 HTH-like domain 39 92 2.2E-14 T 12-10-2018 IPR025948 HTH-like domain HW35_12810 66834e9b41b3beaf373322fb34e336b6 115 SUPERFAMILY SSF46785 9 108 3.4E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_12810 66834e9b41b3beaf373322fb34e336b6 115 Pfam PF03551 Transcriptional regulator PadR-like family 19 85 1.0E-17 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal HW35_12810 66834e9b41b3beaf373322fb34e336b6 115 Gene3D G3DSA:1.10.10.10 1 114 9.5E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_14110 63d9807137def8a9231dec3e573c8780 300 SUPERFAMILY SSF161098 93 280 7.59E-33 T 12-10-2018 IPR035906 MetI-like superfamily HW35_14110 63d9807137def8a9231dec3e573c8780 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 75 1.0E-15 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HW35_14110 63d9807137def8a9231dec3e573c8780 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 299 1.5E-32 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_14110 63d9807137def8a9231dec3e573c8780 300 Gene3D G3DSA:1.10.3720.10 87 300 3.4E-28 T 12-10-2018 IPR035906 MetI-like superfamily HW35_07690 c4988af43614245c3b5ea70b8ac342ba 271 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 1 259 1.7E-84 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 HW35_07690 c4988af43614245c3b5ea70b8ac342ba 271 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 260 18.356 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 HW35_07690 c4988af43614245c3b5ea70b8ac342ba 271 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 255 1.5E-79 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 HW35_07690 c4988af43614245c3b5ea70b8ac342ba 271 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 HW35_13560 89e012d1a69f1ab897bb7ec6555f1ec7 82 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 11 76 7.6E-6 T 12-10-2018 IPR018720 Domain of unknown function DUF2249 HW35_04065 8aa6cf046a218b655cb4fd141f46e351 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 305 317 8.5E-7 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_04065 8aa6cf046a218b655cb4fd141f46e351 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 8.5E-7 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HW35_04065 8aa6cf046a218b655cb4fd141f46e351 353 Gene3D G3DSA:3.90.230.10 126 353 2.0E-87 T 12-10-2018 HW35_04065 8aa6cf046a218b655cb4fd141f46e351 353 Gene3D G3DSA:3.40.350.10 1 125 9.3E-40 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HW35_04065 8aa6cf046a218b655cb4fd141f46e351 353 SUPERFAMILY SSF53092 2 126 3.4E-27 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HW35_04065 8aa6cf046a218b655cb4fd141f46e351 353 SUPERFAMILY SSF55920 84 347 3.14E-85 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like HW35_04065 8aa6cf046a218b655cb4fd141f46e351 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 127 2.4E-28 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 HW35_04065 8aa6cf046a218b655cb4fd141f46e351 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site HW35_04065 8aa6cf046a218b655cb4fd141f46e351 353 Pfam PF00557 Metallopeptidase family M24 136 336 2.0E-70 T 12-10-2018 IPR000994 Peptidase M24 HW35_03785 3ab9ee1dc5bf2bd4290a8aa8ede97d6e 68 Pfam PF09360 Iron-binding zinc finger CDGSH type 11 55 7.1E-19 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 HW35_03785 3ab9ee1dc5bf2bd4290a8aa8ede97d6e 68 SMART SM00704 15 60 5.2E-6 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 HW35_03785 3ab9ee1dc5bf2bd4290a8aa8ede97d6e 68 Gene3D G3DSA:3.40.5.90 2 65 1.2E-16 T 12-10-2018 HW35_12040 5a2a677815712d62be1b567b2cf78ace 475 Pfam PF01235 Sodium:alanine symporter family 53 447 9.3E-164 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_12040 5a2a677815712d62be1b567b2cf78ace 475 PRINTS PR00175 Sodium/alanine symporter signature 208 227 4.7E-58 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_12040 5a2a677815712d62be1b567b2cf78ace 475 PRINTS PR00175 Sodium/alanine symporter signature 180 198 4.7E-58 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_12040 5a2a677815712d62be1b567b2cf78ace 475 PRINTS PR00175 Sodium/alanine symporter signature 299 317 4.7E-58 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_12040 5a2a677815712d62be1b567b2cf78ace 475 PRINTS PR00175 Sodium/alanine symporter signature 90 112 4.7E-58 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_12040 5a2a677815712d62be1b567b2cf78ace 475 PRINTS PR00175 Sodium/alanine symporter signature 344 366 4.7E-58 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_12040 5a2a677815712d62be1b567b2cf78ace 475 PRINTS PR00175 Sodium/alanine symporter signature 404 424 4.7E-58 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_12040 5a2a677815712d62be1b567b2cf78ace 475 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 90 105 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_12040 5a2a677815712d62be1b567b2cf78ace 475 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 435 2.6E-157 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_04780 f6eddb3c077fab19075cf8cc93cc3fc2 359 Pfam PF01594 AI-2E family transporter 20 340 3.0E-75 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like HW35_05105 b6c2ab40a57812f5c4ad0a8120817f65 359 Pfam PF05036 Sporulation related domain 179 245 6.6E-5 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 HW35_05105 b6c2ab40a57812f5c4ad0a8120817f65 359 SUPERFAMILY SSF110997 180 247 5.1E-8 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 HW35_05105 b6c2ab40a57812f5c4ad0a8120817f65 359 Gene3D G3DSA:3.30.70.1070 180 248 1.8E-8 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 HW35_14130 74906346a7cb30f9576d6a92515f267f 411 Gene3D G3DSA:3.60.70.12 9 197 2.3E-71 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HW35_14130 74906346a7cb30f9576d6a92515f267f 411 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 41 411 3.0E-130 T 12-10-2018 HW35_14130 74906346a7cb30f9576d6a92515f267f 411 Gene3D G3DSA:3.30.2330.10 198 282 1.1E-31 T 12-10-2018 HW35_14130 74906346a7cb30f9576d6a92515f267f 411 Gene3D G3DSA:3.10.20.340 283 411 1.3E-49 T 12-10-2018 HW35_14130 74906346a7cb30f9576d6a92515f267f 411 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 411 142.539 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HW35_14130 74906346a7cb30f9576d6a92515f267f 411 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 18 411 2.0E-158 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HW35_14130 74906346a7cb30f9576d6a92515f267f 411 SUPERFAMILY SSF56266 23 407 6.8E-137 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HW35_14130 74906346a7cb30f9576d6a92515f267f 411 Pfam PF01960 ArgJ family 28 411 7.0E-153 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HW35_00305 3804ac7c897def2a028125c6bdb42652 277 Pfam PF00665 Integrase core domain 117 228 1.4E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_00305 3804ac7c897def2a028125c6bdb42652 277 Gene3D G3DSA:3.30.420.10 115 258 2.7E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_00305 3804ac7c897def2a028125c6bdb42652 277 Pfam PF13276 HTH-like domain 34 87 1.8E-13 T 12-10-2018 IPR025948 HTH-like domain HW35_00305 3804ac7c897def2a028125c6bdb42652 277 SUPERFAMILY SSF53098 119 270 8.5E-32 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_12830 90f8409a22d7523ed9b7816f00495123 251 SUPERFAMILY SSF142695 78 221 2.22E-44 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 HW35_12830 90f8409a22d7523ed9b7816f00495123 251 Pfam PF00925 GTP cyclohydrolase II 77 217 1.1E-44 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 HW35_12830 90f8409a22d7523ed9b7816f00495123 251 Gene3D G3DSA:3.40.50.10990 66 221 1.9E-50 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 HW35_08820 a3207b0393d06ecaac985b4754d7861b 213 Pfam PF02397 Bacterial sugar transferase 16 207 5.4E-68 T 12-10-2018 IPR003362 Bacterial sugar transferase HW35_03495 13b9cb3fbc441edadf031e1f08da6a0c 189 SUPERFAMILY SSF47240 1 185 1.91E-68 T 12-10-2018 IPR009078 Ferritin-like superfamily HW35_03495 13b9cb3fbc441edadf031e1f08da6a0c 189 Pfam PF05067 Manganese containing catalase 1 183 3.3E-75 T 12-10-2018 IPR007760 Manganese catalase HW35_03495 13b9cb3fbc441edadf031e1f08da6a0c 189 Gene3D G3DSA:1.20.1260.10 1 184 1.7E-63 T 12-10-2018 IPR012347 Ferritin-like HW35_13805 cc23d61ade5118fb89dd28d8992d0e69 431 Pfam PF02040 Arsenical pump membrane protein 6 427 1.9E-215 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HW35_13805 cc23d61ade5118fb89dd28d8992d0e69 431 PRINTS PR00758 Arsenical pump membrane protein signature 326 348 4.4E-110 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HW35_13805 cc23d61ade5118fb89dd28d8992d0e69 431 PRINTS PR00758 Arsenical pump membrane protein signature 220 245 4.4E-110 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HW35_13805 cc23d61ade5118fb89dd28d8992d0e69 431 PRINTS PR00758 Arsenical pump membrane protein signature 281 305 4.4E-110 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HW35_13805 cc23d61ade5118fb89dd28d8992d0e69 431 PRINTS PR00758 Arsenical pump membrane protein signature 367 392 4.4E-110 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HW35_13805 cc23d61ade5118fb89dd28d8992d0e69 431 PRINTS PR00758 Arsenical pump membrane protein signature 400 424 4.4E-110 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HW35_13805 cc23d61ade5118fb89dd28d8992d0e69 431 PRINTS PR00758 Arsenical pump membrane protein signature 147 171 4.4E-110 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HW35_13805 cc23d61ade5118fb89dd28d8992d0e69 431 PRINTS PR00758 Arsenical pump membrane protein signature 104 128 4.4E-110 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HW35_13805 cc23d61ade5118fb89dd28d8992d0e69 431 PRINTS PR00758 Arsenical pump membrane protein signature 180 203 4.4E-110 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HW35_13805 cc23d61ade5118fb89dd28d8992d0e69 431 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 6 430 1.7E-222 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HW35_11355 309b7e090b51f8ece4ffde3a52ff6387 113 SUPERFAMILY SSF103481 8 101 3.4E-14 T 12-10-2018 HW35_11355 309b7e090b51f8ece4ffde3a52ff6387 113 Pfam PF00893 Small Multidrug Resistance protein 4 91 5.4E-21 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 HW35_11355 309b7e090b51f8ece4ffde3a52ff6387 113 Gene3D G3DSA:1.10.3730.20 3 107 4.7E-22 T 12-10-2018 HW35_05930 db4dde7618a57e489444b3297636b495 110 Pfam PF11009 Protein of unknown function (DUF2847) 3 102 1.1E-36 T 12-10-2018 IPR022551 Protein of unknown function DUF2847 HW35_05930 db4dde7618a57e489444b3297636b495 110 SUPERFAMILY SSF52833 4 90 4.6E-8 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_05930 db4dde7618a57e489444b3297636b495 110 Gene3D G3DSA:3.40.30.10 1 107 3.5E-39 T 12-10-2018 HW35_05930 db4dde7618a57e489444b3297636b495 110 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 3 104 3.0E-37 T 12-10-2018 IPR022551 Protein of unknown function DUF2847 HW35_03200 16f23f69ea3b0109777867fd3cb823ee 283 Gene3D G3DSA:3.60.15.10 37 279 9.0E-13 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_03200 16f23f69ea3b0109777867fd3cb823ee 283 SUPERFAMILY SSF56281 37 276 1.12E-8 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_09185 0a2b6884af7f64a27d8e3f6777d82bf9 297 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 27 291 3.6E-83 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 HW35_09185 0a2b6884af7f64a27d8e3f6777d82bf9 297 Pfam PF13847 Methyltransferase domain 118 255 1.1E-10 T 12-10-2018 IPR025714 Methyltransferase domain HW35_09185 0a2b6884af7f64a27d8e3f6777d82bf9 297 SUPERFAMILY SSF53335 5 293 5.15E-48 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_09185 0a2b6884af7f64a27d8e3f6777d82bf9 297 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 198 204 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HW35_09185 0a2b6884af7f64a27d8e3f6777d82bf9 297 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 5 295 41.413 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 HW35_09185 0a2b6884af7f64a27d8e3f6777d82bf9 297 Gene3D G3DSA:3.40.50.150 87 295 6.4E-65 T 12-10-2018 HW35_09185 0a2b6884af7f64a27d8e3f6777d82bf9 297 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 5 293 2.1E-73 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 HW35_09185 0a2b6884af7f64a27d8e3f6777d82bf9 297 Gene3D G3DSA:1.10.8.10 4 86 8.0E-17 T 12-10-2018 HW35_09945 958d1817071090c025aab02f1df21460 461 Pfam PF01926 50S ribosome-binding GTPase 227 338 1.2E-25 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_09945 958d1817071090c025aab02f1df21460 461 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 227 373 6.7E-29 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HW35_09945 958d1817071090c025aab02f1df21460 461 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 461 9.2E-135 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 HW35_09945 958d1817071090c025aab02f1df21460 461 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 126 9.7E-41 T 12-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 HW35_09945 958d1817071090c025aab02f1df21460 461 Gene3D G3DSA:3.30.1360.120 1 126 5.7E-50 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 HW35_09945 958d1817071090c025aab02f1df21460 461 Gene3D G3DSA:3.40.50.300 224 389 3.8E-110 T 12-10-2018 HW35_09945 958d1817071090c025aab02f1df21460 461 Gene3D G3DSA:1.20.120.430 127 461 3.8E-110 T 12-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 HW35_09945 958d1817071090c025aab02f1df21460 461 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 461 34.945 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 HW35_09945 958d1817071090c025aab02f1df21460 461 Pfam PF12631 MnmE helical domain 129 458 6.6E-61 T 12-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 HW35_09945 958d1817071090c025aab02f1df21460 461 PRINTS PR00449 Transforming protein P21 ras signature 328 341 8.3E-8 T 12-10-2018 HW35_09945 958d1817071090c025aab02f1df21460 461 PRINTS PR00449 Transforming protein P21 ras signature 264 286 8.3E-8 T 12-10-2018 HW35_09945 958d1817071090c025aab02f1df21460 461 PRINTS PR00449 Transforming protein P21 ras signature 359 381 8.3E-8 T 12-10-2018 HW35_09945 958d1817071090c025aab02f1df21460 461 PRINTS PR00449 Transforming protein P21 ras signature 224 245 8.3E-8 T 12-10-2018 HW35_09945 958d1817071090c025aab02f1df21460 461 SUPERFAMILY SSF52540 80 378 1.81E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_15205 0136f4b63c8276ca15f3945f1309da7b 232 Pfam PF04405 Domain of Unknown function (DUF542) 10 62 2.1E-16 T 12-10-2018 IPR019903 Repair of iron centres family HW35_15205 0136f4b63c8276ca15f3945f1309da7b 232 Pfam PF01814 Hemerythrin HHE cation binding domain 86 230 1.2E-21 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 HW35_15205 0136f4b63c8276ca15f3945f1309da7b 232 Gene3D G3DSA:1.20.120.520 85 231 6.1E-19 T 12-10-2018 HW35_15205 0136f4b63c8276ca15f3945f1309da7b 232 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 12 230 7.5E-75 T 12-10-2018 IPR019903 Repair of iron centres family HW35_01170 fb1a83c8381dc9c1b9b9cb0351ca0edf 428 Pfam PF14697 4Fe-4S dicluster domain 335 397 4.5E-23 T 12-10-2018 HW35_01170 fb1a83c8381dc9c1b9b9cb0351ca0edf 428 SUPERFAMILY SSF54862 335 409 6.05E-13 T 12-10-2018 HW35_01170 fb1a83c8381dc9c1b9b9cb0351ca0edf 428 Gene3D G3DSA:3.30.70.20 305 413 2.3E-21 T 12-10-2018 HW35_01170 fb1a83c8381dc9c1b9b9cb0351ca0edf 428 Gene3D G3DSA:3.20.20.70 4 304 5.4E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_01170 fb1a83c8381dc9c1b9b9cb0351ca0edf 428 SUPERFAMILY SSF51395 1 318 7.0E-74 T 12-10-2018 HW35_01170 fb1a83c8381dc9c1b9b9cb0351ca0edf 428 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 379 390 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_01170 fb1a83c8381dc9c1b9b9cb0351ca0edf 428 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 317 1.6E-58 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HW35_01170 fb1a83c8381dc9c1b9b9cb0351ca0edf 428 Pfam PF01180 Dihydroorotate dehydrogenase 82 302 7.0E-32 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HW35_03850 912a5d7d63897a65e0b9d09da9250469 137 SUPERFAMILY SSF54593 1 132 4.4E-33 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_03850 912a5d7d63897a65e0b9d09da9250469 137 Gene3D G3DSA:3.10.180.10 1 133 1.0E-43 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HW35_03850 912a5d7d63897a65e0b9d09da9250469 137 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 116 1.1E-23 T 12-10-2018 HW35_03850 912a5d7d63897a65e0b9d09da9250469 137 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 131 2.5E-47 T 12-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 HW35_06880 91bfae2294c6d1851bc357947d053392 207 Gene3D G3DSA:3.30.420.10 5 202 4.9E-42 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_06880 91bfae2294c6d1851bc357947d053392 207 Pfam PF00929 Exonuclease 8 175 4.3E-23 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HW35_06880 91bfae2294c6d1851bc357947d053392 207 SUPERFAMILY SSF53098 7 181 1.52E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_06880 91bfae2294c6d1851bc357947d053392 207 SMART SM00479 6 184 8.8E-27 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HW35_14730 dde19cfe9e370c9fbd51d11a3c420b3c 121 SUPERFAMILY SSF81442 5 119 7.98E-6 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_14730 dde19cfe9e370c9fbd51d11a3c420b3c 121 Gene3D G3DSA:1.20.210.10 1 121 3.4E-10 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_07300 add6a0cb02913ee82da5fe3e4f47922d 367 Pfam PF03845 Spore germination protein 12 320 2.7E-32 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HW35_07300 add6a0cb02913ee82da5fe3e4f47922d 367 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 7 360 8.9E-60 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HW35_09900 e025bf5761a50a645c87b2f9049ae09c 64 PIRSF PIRSF037263 1 64 2.3E-34 T 12-10-2018 IPR009296 Protein of unknown function DUF951 HW35_09900 e025bf5761a50a645c87b2f9049ae09c 64 Pfam PF06107 Bacterial protein of unknown function (DUF951) 7 59 2.5E-29 T 12-10-2018 IPR009296 Protein of unknown function DUF951 HW35_05980 be931dec701f150e6f5293ef04b6173b 280 Pfam PF00753 Metallo-beta-lactamase superfamily 50 234 1.1E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_05980 be931dec701f150e6f5293ef04b6173b 280 SUPERFAMILY SSF56281 3 261 1.44E-44 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_05980 be931dec701f150e6f5293ef04b6173b 280 Gene3D G3DSA:3.60.15.10 4 268 4.0E-82 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HW35_05980 be931dec701f150e6f5293ef04b6173b 280 SMART SM00849 50 256 1.8E-19 T 12-10-2018 IPR001279 Metallo-beta-lactamase HW35_03995 dbdbcd8753c054ae9275d5ede6b5f39e 171 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 115 129 9.1E-16 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 HW35_03995 dbdbcd8753c054ae9275d5ede6b5f39e 171 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 98 111 9.1E-16 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 HW35_03995 dbdbcd8753c054ae9275d5ede6b5f39e 171 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 130 143 9.1E-16 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 HW35_03995 dbdbcd8753c054ae9275d5ede6b5f39e 171 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 3 169 5.7E-52 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 HW35_03995 dbdbcd8753c054ae9275d5ede6b5f39e 171 Pfam PF00364 Biotin-requiring enzyme 95 166 4.9E-22 T 12-10-2018 IPR000089 Biotin/lipoyl attachment HW35_03995 dbdbcd8753c054ae9275d5ede6b5f39e 171 SUPERFAMILY SSF51230 92 168 9.29E-23 T 12-10-2018 IPR011053 Single hybrid motif HW35_03995 dbdbcd8753c054ae9275d5ede6b5f39e 171 Gene3D G3DSA:2.40.50.100 91 168 1.4E-28 T 12-10-2018 HW35_11095 3c7bf279d61e04a606b301e9d9b757b9 600 Gene3D G3DSA:3.60.20.10 2 240 1.3E-69 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HW35_11095 3c7bf279d61e04a606b301e9d9b757b9 600 Pfam PF01380 SIS domain 289 413 6.6E-34 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HW35_11095 3c7bf279d61e04a606b301e9d9b757b9 600 Pfam PF01380 SIS domain 460 582 2.4E-19 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HW35_11095 3c7bf279d61e04a606b301e9d9b757b9 600 Gene3D G3DSA:3.40.50.10490 445 600 3.2E-62 T 12-10-2018 HW35_11095 3c7bf279d61e04a606b301e9d9b757b9 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 39.143 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 HW35_11095 3c7bf279d61e04a606b301e9d9b757b9 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 3.2E-228 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 HW35_11095 3c7bf279d61e04a606b301e9d9b757b9 600 Pfam PF13522 Glutamine amidotransferase domain 58 191 6.1E-20 T 12-10-2018 HW35_11095 3c7bf279d61e04a606b301e9d9b757b9 600 Gene3D G3DSA:3.40.50.10490 243 442 4.7E-65 T 12-10-2018 HW35_11095 3c7bf279d61e04a606b301e9d9b757b9 600 SUPERFAMILY SSF56235 2 235 1.97E-65 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HW35_11095 3c7bf279d61e04a606b301e9d9b757b9 600 SUPERFAMILY SSF53697 244 600 3.08E-96 T 12-10-2018 HW35_06570 a0990a699f0b68fe71246c4c5f4541d2 513 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 148 173 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site HW35_06570 a0990a699f0b68fe71246c4c5f4541d2 513 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 434 1.5E-88 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 HW35_06570 a0990a699f0b68fe71246c4c5f4541d2 513 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 416 436 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site HW35_06570 a0990a699f0b68fe71246c4c5f4541d2 513 Pfam PF00474 Sodium:solute symporter family 33 434 1.6E-123 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 HW35_06570 a0990a699f0b68fe71246c4c5f4541d2 513 Gene3D G3DSA:1.20.1730.10 20 475 2.6E-67 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 Gene3D G3DSA:3.40.50.720 1 222 7.8E-64 T 12-10-2018 HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 PIRSF PIRSF000126 1 221 3.9E-51 T 12-10-2018 HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 SUPERFAMILY SSF51735 2 217 2.32E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 5.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 5.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 5.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 6.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 6.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 6.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 6.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 6.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 6.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_14215 294a36b5851bcf358777d0d8ba7df496 222 Pfam PF00106 short chain dehydrogenase 2 189 1.6E-52 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_04495 6e5887158fcf62327efe99b00a6b95da 398 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 5 388 3.5E-121 T 12-10-2018 IPR010690 Putative stage IV sporulation YqfD HW35_04495 6e5887158fcf62327efe99b00a6b95da 398 PIRSF PIRSF029895 1 398 1.6E-154 T 12-10-2018 IPR010690 Putative stage IV sporulation YqfD HW35_04495 6e5887158fcf62327efe99b00a6b95da 398 Pfam PF06898 Putative stage IV sporulation protein YqfD 8 386 4.1E-121 T 12-10-2018 IPR010690 Putative stage IV sporulation YqfD HW35_06310 afa21fb049d268fdf4f0b6282e538070 102 SUPERFAMILY SSF46689 1 87 1.47E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_06310 afa21fb049d268fdf4f0b6282e538070 102 Pfam PF01527 Transposase 2 76 2.5E-15 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_02155 b1281d25ea9e924de77f253d7ea41842 236 Gene3D G3DSA:3.40.50.150 10 236 2.5E-46 T 12-10-2018 HW35_02155 b1281d25ea9e924de77f253d7ea41842 236 SUPERFAMILY SSF53335 18 205 3.35E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_02155 b1281d25ea9e924de77f253d7ea41842 236 Pfam PF08241 Methyltransferase domain 42 136 7.3E-26 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 HW35_07190 c13aecfe47048ad774c9e66b0bf41512 334 Pfam PF01032 FecCD transport family 19 329 1.1E-92 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 HW35_07190 c13aecfe47048ad774c9e66b0bf41512 334 SUPERFAMILY SSF81345 5 329 7.59E-81 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_07190 c13aecfe47048ad774c9e66b0bf41512 334 Gene3D G3DSA:1.10.3470.10 7 333 9.9E-91 T 12-10-2018 IPR037294 ABC transporter, BtuC-like HW35_00180 8a5d2d69967e47975c174cde6b6951c1 167 Pfam PF00583 Acetyltransferase (GNAT) family 40 140 2.8E-14 T 12-10-2018 IPR000182 GNAT domain HW35_00180 8a5d2d69967e47975c174cde6b6951c1 167 Gene3D G3DSA:3.40.630.30 3 167 1.4E-42 T 12-10-2018 HW35_00180 8a5d2d69967e47975c174cde6b6951c1 167 SUPERFAMILY SSF55729 5 165 2.45E-31 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_15710 6e983065e73745f359f2150dbc3a33cd 431 SUPERFAMILY SSF51905 1 382 1.08E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_15710 6e983065e73745f359f2150dbc3a33cd 431 SUPERFAMILY SSF54373 182 284 1.69E-18 T 12-10-2018 HW35_15710 6e983065e73745f359f2150dbc3a33cd 431 Pfam PF12831 FAD dependent oxidoreductase 6 155 2.1E-11 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal HW35_15710 6e983065e73745f359f2150dbc3a33cd 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 4.0E-8 T 12-10-2018 HW35_15710 6e983065e73745f359f2150dbc3a33cd 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 310 4.0E-8 T 12-10-2018 HW35_15710 6e983065e73745f359f2150dbc3a33cd 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 4.0E-8 T 12-10-2018 HW35_15710 6e983065e73745f359f2150dbc3a33cd 431 Gene3D G3DSA:3.50.50.60 1 429 7.7E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HW35_13390 86680ece8a4ea15b43ddc343694242e5 371 Gene3D G3DSA:3.40.50.2300 157 328 6.0E-77 T 12-10-2018 HW35_13390 86680ece8a4ea15b43ddc343694242e5 371 Gene3D G3DSA:3.40.50.2300 55 322 6.0E-77 T 12-10-2018 HW35_13390 86680ece8a4ea15b43ddc343694242e5 371 SUPERFAMILY SSF53822 52 334 1.53E-54 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_13390 86680ece8a4ea15b43ddc343694242e5 371 Pfam PF13407 Periplasmic binding protein domain 60 315 1.3E-35 T 12-10-2018 IPR025997 Periplasmic binding protein HW35_02265 c3fef22b65aa736fc446e49928403b52 307 Pfam PF13411 MerR HTH family regulatory protein 4 73 1.3E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_02265 c3fef22b65aa736fc446e49928403b52 307 SMART SM00422 4 74 0.0057 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HW35_02265 c3fef22b65aa736fc446e49928403b52 307 Gene3D G3DSA:1.10.1660.10 1 110 1.7E-12 T 12-10-2018 HW35_02265 c3fef22b65aa736fc446e49928403b52 307 SUPERFAMILY SSF46955 4 80 1.24E-9 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily HW35_02800 af4892b9b4bcd9abf509756a0d230e6e 83 Pfam PF10751 Protein of unknown function (DUF2535) 1 83 2.9E-38 T 12-10-2018 IPR019687 Protein of unknown function DUF2535 HW35_14740 4d20e8fba3a93f43d59a6fd9693ded0f 418 Pfam PF04286 Protein of unknown function (DUF445) 43 416 2.3E-79 T 12-10-2018 IPR007383 Protein of unknown function DUF445 HW35_05540 1ff8417550cdfa6933fcc83c59c438d7 69 Pfam PF14098 Small, acid-soluble spore protein I 3 67 8.9E-31 T 12-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 HW35_05540 1ff8417550cdfa6933fcc83c59c438d7 69 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 22.256 T 12-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 HW35_05540 1ff8417550cdfa6933fcc83c59c438d7 69 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 3.7E-34 T 12-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 Pfam PF00072 Response regulator receiver domain 4 115 1.4E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 SUPERFAMILY SSF46894 142 209 6.12E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 6.6E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 6.6E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 6.6E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 Gene3D G3DSA:3.40.50.12740 2 209 2.3E-77 T 12-10-2018 HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 SUPERFAMILY SSF52172 1 131 4.84E-34 T 12-10-2018 IPR011006 CheY-like superfamily HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 SMART SM00448 2 115 5.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 SMART SM00421 146 203 2.4E-28 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_13615 cb9cfef20a75d56edf6e0865877f1b23 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 9.9E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HW35_11820 04d313416999edb603d5f86a9c23e9e8 97 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 27.193 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HW35_11820 04d313416999edb603d5f86a9c23e9e8 97 SUPERFAMILY SSF141000 4 94 3.27E-35 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 HW35_11820 04d313416999edb603d5f86a9c23e9e8 97 Gene3D G3DSA:1.10.20.60 1 94 8.8E-35 T 12-10-2018 HW35_11820 04d313416999edb603d5f86a9c23e9e8 97 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 1.6E-36 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HW35_11820 04d313416999edb603d5f86a9c23e9e8 97 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 2.0E-25 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HW35_13030 ea23bd10f2a731ec3d6899ffd6f80231 157 Gene3D G3DSA:3.30.1330.40 4 151 9.3E-61 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 HW35_13030 ea23bd10f2a731ec3d6899ffd6f80231 157 SUPERFAMILY SSF55298 7 151 3.46E-53 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 HW35_13030 ea23bd10f2a731ec3d6899ffd6f80231 157 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 9 150 9.1E-35 T 12-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 1.7E-87 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 SUPERFAMILY SSF52283 1 360 5.19E-71 T 12-10-2018 HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 SMART SM01002 148 297 3.1E-93 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 1.4E-47 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 12-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 PIRSF PIRSF000183 1 371 9.2E-198 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 SMART SM01003 4 136 2.5E-80 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 369 1.6E-183 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 SUPERFAMILY SSF51735 136 303 1.02E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 Gene3D G3DSA:3.40.50.720 129 305 1.0E-144 T 12-10-2018 HW35_05760 48155d7cf1db73e691df1d3c2e35f35a 371 Gene3D G3DSA:3.40.50.720 3 353 1.0E-144 T 12-10-2018 HW35_16275 c44bcf6fd37e36a302ba9c031eeeab15 544 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 12 542 6.8E-178 T 12-10-2018 IPR011199 Bacillithiol biosynthesis BshC HW35_16275 c44bcf6fd37e36a302ba9c031eeeab15 544 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 544 30.644 T 12-10-2018 IPR011199 Bacillithiol biosynthesis BshC HW35_16275 c44bcf6fd37e36a302ba9c031eeeab15 544 Pfam PF10079 Bacillithiol biosynthesis BshC 1 541 4.2E-171 T 12-10-2018 IPR011199 Bacillithiol biosynthesis BshC HW35_16275 c44bcf6fd37e36a302ba9c031eeeab15 544 PIRSF PIRSF012535 1 544 1.3E-182 T 12-10-2018 IPR011199 Bacillithiol biosynthesis BshC HW35_15475 8256f936d5a8ef79965e9d40132dcc36 241 SUPERFAMILY SSF53474 2 239 1.22E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_15475 8256f936d5a8ef79965e9d40132dcc36 241 Pfam PF00756 Putative esterase 15 238 3.7E-49 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 HW35_15475 8256f936d5a8ef79965e9d40132dcc36 241 Gene3D G3DSA:3.40.50.1820 1 241 3.9E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_00860 479ddb7f82c22f38c8615311fb47bf62 474 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 7 463 4.4E-217 T 12-10-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00500+2.7.1.201 HW35_00860 479ddb7f82c22f38c8615311fb47bf62 474 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 110 1.0E-17 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HW35_00860 479ddb7f82c22f38c8615311fb47bf62 474 Pfam PF02378 Phosphotransferase system, EIIC 111 407 2.8E-40 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HW35_00860 479ddb7f82c22f38c8615311fb47bf62 474 SUPERFAMILY SSF55604 8 81 1.83E-21 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 HW35_00860 479ddb7f82c22f38c8615311fb47bf62 474 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HW35_00860 479ddb7f82c22f38c8615311fb47bf62 474 Gene3D G3DSA:3.30.1360.60 1 77 2.9E-25 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 HW35_00860 479ddb7f82c22f38c8615311fb47bf62 474 Pfam PF00367 phosphotransferase system, EIIB 9 42 4.7E-15 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HW35_07030 593d157e656740faedf004d2401319ba 281 Gene3D G3DSA:3.20.20.410 1 281 6.6E-96 T 12-10-2018 IPR036520 UPF0759 superfamily HW35_07030 593d157e656740faedf004d2401319ba 281 SUPERFAMILY SSF117396 2 268 3.14E-86 T 12-10-2018 IPR036520 UPF0759 superfamily HW35_07030 593d157e656740faedf004d2401319ba 281 Pfam PF01904 Protein of unknown function DUF72 16 264 1.1E-61 T 12-10-2018 IPR002763 Protein of unknown function DUF72 HW35_12410 4cee74bd462b3d471adb89c39d0e6e80 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 214 5.1E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_12410 4cee74bd462b3d471adb89c39d0e6e80 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 1.4E-30 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 HW35_12410 4cee74bd462b3d471adb89c39d0e6e80 216 SUPERFAMILY SSF161098 15 204 5.36E-44 T 12-10-2018 IPR035906 MetI-like superfamily HW35_12410 4cee74bd462b3d471adb89c39d0e6e80 216 Gene3D G3DSA:1.10.3720.10 5 216 2.0E-53 T 12-10-2018 IPR035906 MetI-like superfamily HW35_00175 61693f8bf2e4b2697d07bef595774bdc 382 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 363 2.3E-77 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HW35_00175 61693f8bf2e4b2697d07bef595774bdc 382 Pfam PF03845 Spore germination protein 5 324 1.9E-87 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HW35_16055 23ea1a7fe43f4ce33b44d3bed124d8f3 165 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 4 164 3.0E-48 T 12-10-2018 IPR020229 Uncharacterised protein YlaL HW35_14605 7875ffe7b74a333360e69079966d846f 388 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 8 379 4.1E-183 T 12-10-2018 IPR014230 Sporulation protein YhbH HW35_14605 7875ffe7b74a333360e69079966d846f 388 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 6 384 31.734 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 HW35_14605 7875ffe7b74a333360e69079966d846f 388 Pfam PF04285 Protein of unknown function (DUF444) 191 382 3.9E-68 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 HW35_14605 7875ffe7b74a333360e69079966d846f 388 Pfam PF04285 Protein of unknown function (DUF444) 13 183 5.6E-34 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 HW35_07965 1d68a9ef1099fd325532892467d4c137 294 SUPERFAMILY SSF53448 2 267 2.92E-69 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_07965 1d68a9ef1099fd325532892467d4c137 294 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 263 6.4E-119 T 12-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 HW35_07965 1d68a9ef1099fd325532892467d4c137 294 Gene3D G3DSA:3.90.550.10 1 289 1.2E-92 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HW35_07965 1d68a9ef1099fd325532892467d4c137 294 Pfam PF00483 Nucleotidyl transferase 5 263 3.3E-35 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HW35_10770 b2949b5ca1922d9f1bf349bead555456 102 SUPERFAMILY SSF50104 1 96 8.53E-37 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily HW35_10770 b2949b5ca1922d9f1bf349bead555456 102 SMART SM00739 2 29 4.6E-7 T 12-10-2018 IPR005824 KOW HW35_10770 b2949b5ca1922d9f1bf349bead555456 102 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_10770 b2949b5ca1922d9f1bf349bead555456 102 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 96 1.8E-38 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10770 b2949b5ca1922d9f1bf349bead555456 102 Gene3D G3DSA:2.30.30.30 1 98 1.7E-40 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 HW35_10770 b2949b5ca1922d9f1bf349bead555456 102 Pfam PF00467 KOW motif 5 36 2.8E-9 T 12-10-2018 IPR005824 KOW HW35_10770 b2949b5ca1922d9f1bf349bead555456 102 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 22.341 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10770 b2949b5ca1922d9f1bf349bead555456 102 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 99 2.1E-28 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_00730 a4b4f5f3e0eb4002b2342d72f6de73e8 255 SUPERFAMILY SSF53474 4 252 2.3E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_00730 a4b4f5f3e0eb4002b2342d72f6de73e8 255 Pfam PF00561 alpha/beta hydrolase fold 22 133 6.6E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_00730 a4b4f5f3e0eb4002b2342d72f6de73e8 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 6.3E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_00730 a4b4f5f3e0eb4002b2342d72f6de73e8 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 6.3E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_00730 a4b4f5f3e0eb4002b2342d72f6de73e8 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 6.3E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 HW35_00730 a4b4f5f3e0eb4002b2342d72f6de73e8 255 Gene3D G3DSA:3.40.50.1820 2 254 3.6E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_08830 eca9dc6c9e0e097388f4faaa2ce7ef9a 253 SUPERFAMILY SSF89550 2 198 3.69E-13 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HW35_08830 eca9dc6c9e0e097388f4faaa2ce7ef9a 253 Gene3D G3DSA:3.20.20.140 1 253 1.1E-95 T 12-10-2018 HW35_08830 eca9dc6c9e0e097388f4faaa2ce7ef9a 253 PIRSF PIRSF016557 1 253 3.6E-105 T 12-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 HW35_10955 64951b688dcca573410db5452b032cb6 495 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 18 472 9.5E-157 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HW35_10955 64951b688dcca573410db5452b032cb6 495 PIRSF PIRSF005690 4 486 4.5E-149 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HW35_03695 27c6e32c9051aeb3de27fd3f14437a8f 272 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 22 268 7.4E-120 T 12-10-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 HW35_03695 27c6e32c9051aeb3de27fd3f14437a8f 272 Gene3D G3DSA:3.40.50.1580 1 270 9.1E-117 T 12-10-2018 HW35_03695 27c6e32c9051aeb3de27fd3f14437a8f 272 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 75 116 - T 12-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 HW35_03695 27c6e32c9051aeb3de27fd3f14437a8f 272 Pfam PF01048 Phosphorylase superfamily 22 268 4.0E-57 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HW35_03695 27c6e32c9051aeb3de27fd3f14437a8f 272 SUPERFAMILY SSF53167 3 271 9.82E-103 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 HW35_03695 27c6e32c9051aeb3de27fd3f14437a8f 272 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 22 269 2.7E-114 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 HW35_03695 27c6e32c9051aeb3de27fd3f14437a8f 272 PIRSF PIRSF000477 1 271 9.8E-122 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 HW35_16430 cf38e92e5cc5e0b37f3f0679abed9eff 171 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 1.6E-18 T 12-10-2018 IPR019933 DivIVA domain HW35_16430 cf38e92e5cc5e0b37f3f0679abed9eff 171 Pfam PF05103 DivIVA protein 3 133 6.0E-52 T 12-10-2018 IPR007793 DivIVA family HW35_00975 44ec5195ab4e28ed05b82eb83de63c22 265 SUPERFAMILY SSF53639 5 211 5.1E-63 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily HW35_00975 44ec5195ab4e28ed05b82eb83de63c22 265 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 184 4.0E-49 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal HW35_00975 44ec5195ab4e28ed05b82eb83de63c22 265 SMART SM01007 9 185 5.8E-65 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal HW35_00975 44ec5195ab4e28ed05b82eb83de63c22 265 Gene3D G3DSA:3.40.225.10 2 214 9.2E-71 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily HW35_11880 604cf5d585cbb677587d17fced4276be 124 Pfam PF06527 TniQ 6 91 2.8E-8 T 12-10-2018 IPR009492 TniQ HW35_03630 600d6658415f896c9a85096e282d27f1 175 SUPERFAMILY SSF140663 2 128 1.83E-30 T 12-10-2018 IPR023203 TTHA0068-like superfamily HW35_03630 600d6658415f896c9a85096e282d27f1 175 Pfam PF03745 Domain of unknown function (DUF309) 6 65 8.0E-21 T 12-10-2018 IPR005500 Protein of unknown function DUF309 HW35_03630 600d6658415f896c9a85096e282d27f1 175 Gene3D G3DSA:1.20.58.500 3 101 4.1E-13 T 12-10-2018 HW35_09015 2bc4d0583e6715d99e4ae649f65ec779 79 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 9 75 1.2E-23 T 12-10-2018 IPR009526 Protein of unknown function DUF1146 HW35_09015 2bc4d0583e6715d99e4ae649f65ec779 79 Pfam PF06612 Protein of unknown function (DUF1146) 16 63 3.7E-23 T 12-10-2018 IPR009526 Protein of unknown function DUF1146 HW35_12465 10d7de24c36ea494393215cb34c6d5c4 406 Pfam PF12704 MacB-like periplasmic core domain 29 213 4.1E-6 T 12-10-2018 IPR025857 MacB-like periplasmic core domain HW35_11890 ca72e0f3993e7ffbe47090d8ba8c84fb 198 Pfam PF15978 Tn7-like transposition protein D 19 128 4.1E-22 T 12-10-2018 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl HW35_08725 6a43d7e144184bb4edc7bee0063c1f8d 94 Pfam PF10852 Protein of unknown function (DUF2651) 14 79 3.5E-7 T 12-10-2018 IPR020258 Uncharacterised protein family YbeF HW35_07725 e18a9daa8d57e689c408cb89ecf6e27c 491 Pfam PF01235 Sodium:alanine symporter family 51 461 3.2E-154 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_07725 e18a9daa8d57e689c408cb89ecf6e27c 491 TIGRFAM TIGR00835 agcS: amino acid carrier protein 14 449 1.5E-148 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_07725 e18a9daa8d57e689c408cb89ecf6e27c 491 PRINTS PR00175 Sodium/alanine symporter signature 87 109 9.0E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_07725 e18a9daa8d57e689c408cb89ecf6e27c 491 PRINTS PR00175 Sodium/alanine symporter signature 177 195 9.0E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_07725 e18a9daa8d57e689c408cb89ecf6e27c 491 PRINTS PR00175 Sodium/alanine symporter signature 418 438 9.0E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_07725 e18a9daa8d57e689c408cb89ecf6e27c 491 PRINTS PR00175 Sodium/alanine symporter signature 205 224 9.0E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_07725 e18a9daa8d57e689c408cb89ecf6e27c 491 PRINTS PR00175 Sodium/alanine symporter signature 355 377 9.0E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_07725 e18a9daa8d57e689c408cb89ecf6e27c 491 PRINTS PR00175 Sodium/alanine symporter signature 296 314 9.0E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HW35_04305 d6e907433c9db0925858e9a2466b7c92 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 313 2.4E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_04305 d6e907433c9db0925858e9a2466b7c92 317 SUPERFAMILY SSF161098 40 309 4.39E-36 T 12-10-2018 IPR035906 MetI-like superfamily HW35_04305 d6e907433c9db0925858e9a2466b7c92 317 Gene3D G3DSA:1.10.3720.10 88 315 2.3E-38 T 12-10-2018 IPR035906 MetI-like superfamily HW35_04305 d6e907433c9db0925858e9a2466b7c92 317 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 30 312 1.7E-80 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 HW35_00795 5eb5f8c5951e504a38763ba997aaf566 148 Pfam PF10710 Protein of unknown function (DUF2512) 1 132 9.1E-41 T 12-10-2018 IPR019649 Protein of unknown function DUF2512 HW35_16060 92f98f0fd990a615f4af9ddb11d466b3 94 SUPERFAMILY SSF140404 7 85 3.14E-37 T 12-10-2018 IPR036270 UPF0358 superfamily HW35_16060 92f98f0fd990a615f4af9ddb11d466b3 94 Gene3D G3DSA:1.10.287.750 5 93 7.7E-37 T 12-10-2018 IPR036270 UPF0358 superfamily HW35_16060 92f98f0fd990a615f4af9ddb11d466b3 94 Hamap MF_01560 UPF0358 protein . 4 94 27.088 T 12-10-2018 IPR009983 Uncharacterised protein family UPF0358 HW35_16060 92f98f0fd990a615f4af9ddb11d466b3 94 Pfam PF07408 Protein of unknown function (DUF1507) 10 91 1.4E-41 T 12-10-2018 IPR009983 Uncharacterised protein family UPF0358 HW35_10870 03efdf7c1436c859cd116f7d3f7b8137 245 SUPERFAMILY SSF55120 1 245 1.34E-88 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_10870 03efdf7c1436c859cd116f7d3f7b8137 245 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 37.058 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_10870 03efdf7c1436c859cd116f7d3f7b8137 245 PIRSF PIRSF001430 1 245 1.4E-84 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_10870 03efdf7c1436c859cd116f7d3f7b8137 245 Pfam PF01416 tRNA pseudouridine synthase 9 104 4.5E-8 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_10870 03efdf7c1436c859cd116f7d3f7b8137 245 Pfam PF01416 tRNA pseudouridine synthase 144 245 4.2E-30 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_10870 03efdf7c1436c859cd116f7d3f7b8137 245 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 240 1.8E-71 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HW35_10870 03efdf7c1436c859cd116f7d3f7b8137 245 Gene3D G3DSA:3.30.70.660 107 244 2.6E-50 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 HW35_10870 03efdf7c1436c859cd116f7d3f7b8137 245 Gene3D G3DSA:3.30.70.580 1 106 5.6E-36 T 12-10-2018 HW35_07840 4bd5284335f71ac4a44b1c5e7bf92d13 111 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 39 107 5.6E-16 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_07840 4bd5284335f71ac4a44b1c5e7bf92d13 111 PIRSF PIRSF000025 1 111 7.6E-36 T 12-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 HW35_07840 4bd5284335f71ac4a44b1c5e7bf92d13 111 SUPERFAMILY SSF46626 1 108 1.13E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HW35_07840 4bd5284335f71ac4a44b1c5e7bf92d13 111 Gene3D G3DSA:1.10.760.10 41 111 8.8E-30 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HW35_12205 d27cf49d33b3c785be54c998bc7ebdb5 354 Pfam PF00296 Luciferase-like monooxygenase 28 309 1.8E-56 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 HW35_12205 d27cf49d33b3c785be54c998bc7ebdb5 354 SUPERFAMILY SSF51679 8 347 3.66E-76 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 HW35_12205 d27cf49d33b3c785be54c998bc7ebdb5 354 Gene3D G3DSA:3.20.20.30 1 354 9.4E-89 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 HW35_00015 6ba5bb6493a161fe74cabe2ef25097cd 71 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 68 17.382 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HW35_00015 6ba5bb6493a161fe74cabe2ef25097cd 71 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 5.0E-9 T 12-10-2018 HW35_00015 6ba5bb6493a161fe74cabe2ef25097cd 71 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 5.0E-9 T 12-10-2018 HW35_00015 6ba5bb6493a161fe74cabe2ef25097cd 71 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 5.0E-9 T 12-10-2018 HW35_00015 6ba5bb6493a161fe74cabe2ef25097cd 71 Pfam PF02416 mttA/Hcf106 family 5 54 4.1E-18 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 HW35_00015 6ba5bb6493a161fe74cabe2ef25097cd 71 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 49 8.8E-18 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HW35_11995 936f99a04b5057ee7994951692375d42 202 SUPERFAMILY SSF53335 22 172 1.64E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_11995 936f99a04b5057ee7994951692375d42 202 Pfam PF13679 Methyltransferase domain 46 107 4.2E-8 T 12-10-2018 IPR025714 Methyltransferase domain HW35_11995 936f99a04b5057ee7994951692375d42 202 Gene3D G3DSA:3.40.50.150 24 170 1.0E-16 T 12-10-2018 HW35_05460 d7480e1beb005d55d1e1fb3600439f1d 257 SMART SM00893 21 211 3.0E-59 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HW35_05460 d7480e1beb005d55d1e1fb3600439f1d 257 Pfam PF01012 Electron transfer flavoprotein domain 23 206 5.3E-49 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HW35_05460 d7480e1beb005d55d1e1fb3600439f1d 257 Gene3D G3DSA:3.40.50.620 1 256 1.5E-83 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_05460 d7480e1beb005d55d1e1fb3600439f1d 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 12-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 HW35_05460 d7480e1beb005d55d1e1fb3600439f1d 257 SUPERFAMILY SSF52402 1 243 1.6E-77 T 12-10-2018 HW35_05460 d7480e1beb005d55d1e1fb3600439f1d 257 PIRSF PIRSF000090 1 257 5.1E-79 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 HW35_09520 e498cfacb82fb32e8dbd2abc5e26dcba 366 SUPERFAMILY SSF52540 30 66 9.47E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09520 e498cfacb82fb32e8dbd2abc5e26dcba 366 SUPERFAMILY SSF52540 214 320 1.98E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09520 e498cfacb82fb32e8dbd2abc5e26dcba 366 Gene3D G3DSA:3.40.50.300 214 251 4.6E-5 T 12-10-2018 HW35_09520 e498cfacb82fb32e8dbd2abc5e26dcba 366 Gene3D G3DSA:3.40.50.300 10 177 1.0E-5 T 12-10-2018 HW35_07540 9455fb74e74e6bf334249a04a5cb889d 446 Pfam PF02386 Cation transport protein 37 427 4.6E-60 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 HW35_07540 9455fb74e74e6bf334249a04a5cb889d 446 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 30 417 2.3E-115 T 12-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 HW35_12280 70c33c11a6e9743d5fac3b08ca47a86b 230 Gene3D G3DSA:3.40.50.2300 3 126 1.8E-28 T 12-10-2018 HW35_12280 70c33c11a6e9743d5fac3b08ca47a86b 230 SUPERFAMILY SSF52172 3 123 1.41E-33 T 12-10-2018 IPR011006 CheY-like superfamily HW35_12280 70c33c11a6e9743d5fac3b08ca47a86b 230 SMART SM00862 149 223 5.7E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_12280 70c33c11a6e9743d5fac3b08ca47a86b 230 SMART SM00448 2 112 1.8E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_12280 70c33c11a6e9743d5fac3b08ca47a86b 230 SUPERFAMILY SSF46894 132 223 4.82E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HW35_12280 70c33c11a6e9743d5fac3b08ca47a86b 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 222 5.4E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HW35_12280 70c33c11a6e9743d5fac3b08ca47a86b 230 Pfam PF00072 Response regulator receiver domain 5 113 2.9E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HW35_12280 70c33c11a6e9743d5fac3b08ca47a86b 230 Gene3D G3DSA:1.10.10.10 128 227 1.9E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_14060 79300b081aa22ccdd2bd524c35bd2b10 187 SUPERFAMILY SSF89155 10 171 5.62E-24 T 12-10-2018 IPR036411 TorD-like superfamily HW35_14060 79300b081aa22ccdd2bd524c35bd2b10 187 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 17 166 1.1E-30 T 12-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 HW35_14060 79300b081aa22ccdd2bd524c35bd2b10 187 Gene3D G3DSA:1.20.120.700 13 164 4.5E-14 T 12-10-2018 HW35_14060 79300b081aa22ccdd2bd524c35bd2b10 187 Gene3D G3DSA:1.10.4070.10 75 156 4.5E-14 T 12-10-2018 HW35_13910 372d450894abbc5a583706a2344f1e18 312 Pfam PF03547 Membrane transport protein 8 156 2.7E-15 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 HW35_13910 372d450894abbc5a583706a2344f1e18 312 Pfam PF03547 Membrane transport protein 159 304 7.2E-12 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 HW35_16345 6f794cba643f6f1247c819e3da8c4a33 239 Gene3D G3DSA:3.30.70.1880 101 238 8.4E-32 T 12-10-2018 HW35_16345 6f794cba643f6f1247c819e3da8c4a33 239 Pfam PF05949 Bacterial protein of unknown function (DUF881) 103 235 4.1E-34 T 12-10-2018 IPR010273 Protein of unknown function DUF881 HW35_06615 12ed7a42c991aa288e0773d97ae6208c 431 SUPERFAMILY SSF58104 95 429 5.49E-60 T 12-10-2018 HW35_06615 12ed7a42c991aa288e0773d97ae6208c 431 Pfam PF00672 HAMP domain 74 123 2.7E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_06615 12ed7a42c991aa288e0773d97ae6208c 431 Gene3D G3DSA:1.10.287.950 73 431 1.2E-55 T 12-10-2018 HW35_06615 12ed7a42c991aa288e0773d97ae6208c 431 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 233 383 8.0E-34 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HW35_06615 12ed7a42c991aa288e0773d97ae6208c 431 SMART SM00304 73 126 9.4E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HW35_06615 12ed7a42c991aa288e0773d97ae6208c 431 SMART SM00283 155 430 3.2E-36 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HW35_14470 d35f564b3256833a4c2b38580c8566a1 68 Pfam PF12844 Helix-turn-helix domain 5 52 2.3E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_14470 d35f564b3256833a4c2b38580c8566a1 68 SUPERFAMILY SSF47413 4 54 2.68E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_14470 d35f564b3256833a4c2b38580c8566a1 68 Gene3D G3DSA:1.10.260.40 3 54 4.2E-10 T 12-10-2018 HW35_01840 2b982f0a5766423aa74adb36e335bcb0 200 Gene3D G3DSA:1.10.1760.20 8 178 3.6E-11 T 12-10-2018 HW35_02550 1a81b2d16e4bdc253a68cbd4d6aa033b 207 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 196 8.4E-49 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 HW35_02550 1a81b2d16e4bdc253a68cbd4d6aa033b 207 Gene3D G3DSA:3.20.20.70 1 204 2.2E-62 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_02550 1a81b2d16e4bdc253a68cbd4d6aa033b 207 SUPERFAMILY SSF51366 1 199 1.57E-51 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HW35_02550 1a81b2d16e4bdc253a68cbd4d6aa033b 207 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 201 35.934 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 HW35_16950 929499e173483d3fad9400c9b97a8d27 426 Gene3D G3DSA:3.30.830.10 5 236 6.8E-66 T 12-10-2018 HW35_16950 929499e173483d3fad9400c9b97a8d27 426 SUPERFAMILY SSF63411 13 224 2.75E-25 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HW35_16950 929499e173483d3fad9400c9b97a8d27 426 Gene3D G3DSA:3.30.830.10 240 425 1.9E-44 T 12-10-2018 HW35_16950 929499e173483d3fad9400c9b97a8d27 426 SUPERFAMILY SSF63411 252 414 5.1E-33 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HW35_16950 929499e173483d3fad9400c9b97a8d27 426 Pfam PF05193 Peptidase M16 inactive domain 185 357 9.2E-26 T 12-10-2018 IPR007863 Peptidase M16, C-terminal HW35_00465 6af31fdd0307d79cb943776d7fc85201 147 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 2 147 9.6E-52 T 12-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 HW35_00465 6af31fdd0307d79cb943776d7fc85201 147 Pfam PF00460 Flagella basal body rod protein 5 32 1.7E-9 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HW35_00465 6af31fdd0307d79cb943776d7fc85201 147 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 97 143 6.7E-12 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HW35_13070 bed1acd3fd42d3df69159aba53d1f430 167 Gene3D G3DSA:3.30.70.1450 85 162 9.3E-21 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_13070 bed1acd3fd42d3df69159aba53d1f430 167 SUPERFAMILY SSF116726 79 158 8.11E-19 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HW35_13070 bed1acd3fd42d3df69159aba53d1f430 167 PIRSF PIRSF005028 1 163 8.0E-55 T 12-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT HW35_13070 bed1acd3fd42d3df69159aba53d1f430 167 Pfam PF02080 TrkA-C domain 90 158 2.5E-16 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HW35_16355 87898589bf9743e024828ea95c8cf10c 120 Pfam PF06947 Protein of unknown function (DUF1290) 22 107 6.3E-37 T 12-10-2018 IPR009709 Protein of unknown function DUF1290 HW35_16355 87898589bf9743e024828ea95c8cf10c 120 PIRSF PIRSF018579 1 113 3.2E-49 T 12-10-2018 IPR009709 Protein of unknown function DUF1290 HW35_12690 928cbfbeca113852b7bc6667cb4c84b4 385 Pfam PF14199 Domain of unknown function (DUF4317) 1 378 1.8E-104 T 12-10-2018 IPR025466 Protein of unknown function DUF4317 HW35_03275 dcba6702608030cb68c2757c19c3afe5 197 Pfam PF07187 Protein of unknown function (DUF1405) 24 182 3.2E-59 T 12-10-2018 IPR009845 Protein of unknown function DUF1405 HW35_00455 32f01037bce4d0c91662b72ee4e2822e 215 SUPERFAMILY SSF53955 97 176 4.19E-6 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily HW35_00455 32f01037bce4d0c91662b72ee4e2822e 215 Gene3D G3DSA:1.10.530.10 98 202 3.3E-8 T 12-10-2018 HW35_00455 32f01037bce4d0c91662b72ee4e2822e 215 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 103 213 1.3E-15 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HW35_13040 c1953b0ae977109b4a9846f9731a40cd 259 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 101 254 2.0E-9 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 HW35_13040 c1953b0ae977109b4a9846f9731a40cd 259 Gene3D G3DSA:3.90.850.10 4 259 4.4E-78 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 HW35_13040 c1953b0ae977109b4a9846f9731a40cd 259 SUPERFAMILY SSF56529 5 258 9.68E-74 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 HW35_02960 fefe75fc9a39a7b34f569acff537cee6 66 Gene3D G3DSA:2.40.50.140 1 66 8.9E-31 T 12-10-2018 HW35_02960 fefe75fc9a39a7b34f569acff537cee6 66 PRINTS PR00050 Cold shock protein signature 24 33 8.9E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_02960 fefe75fc9a39a7b34f569acff537cee6 66 PRINTS PR00050 Cold shock protein signature 4 19 8.9E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_02960 fefe75fc9a39a7b34f569acff537cee6 66 PRINTS PR00050 Cold shock protein signature 39 57 8.9E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_02960 fefe75fc9a39a7b34f569acff537cee6 66 SMART SM00357 3 66 2.3E-31 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 HW35_02960 fefe75fc9a39a7b34f569acff537cee6 66 SUPERFAMILY SSF50249 1 65 9.75E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold HW35_02960 fefe75fc9a39a7b34f569acff537cee6 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site HW35_02960 fefe75fc9a39a7b34f569acff537cee6 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 9.7E-31 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HW35_02960 fefe75fc9a39a7b34f569acff537cee6 66 PIRSF PIRSF002599 1 66 8.8E-25 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 HW35_15190 380213c63681466c27d682f535b76712 374 Gene3D G3DSA:3.20.20.70 5 317 2.4E-48 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_15190 380213c63681466c27d682f535b76712 374 PIRSF PIRSF037420 2 374 3.7E-101 T 12-10-2018 IPR017200 Coenzyme PQQ synthesis protein E HW35_15190 380213c63681466c27d682f535b76712 374 Pfam PF04055 Radical SAM superfamily 18 175 2.6E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HW35_15190 380213c63681466c27d682f535b76712 374 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 6 365 2.4E-159 T 12-10-2018 IPR027634 Radical SAM protein, BA_1875 family HW35_15190 380213c63681466c27d682f535b76712 374 SMART SM00729 12 215 0.0017 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HW35_15190 380213c63681466c27d682f535b76712 374 Pfam PF13353 4Fe-4S single cluster domain 15 123 1.4E-7 T 12-10-2018 HW35_15190 380213c63681466c27d682f535b76712 374 SUPERFAMILY SSF102114 10 342 1.57E-67 T 12-10-2018 HW35_07795 ea101814087a7a1dd58f51299e258cff 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 112 1.1E-24 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 HW35_07795 ea101814087a7a1dd58f51299e258cff 219 Gene3D G3DSA:1.10.3720.10 1 217 2.5E-53 T 12-10-2018 IPR035906 MetI-like superfamily HW35_07795 ea101814087a7a1dd58f51299e258cff 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 217 1.2E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_07795 ea101814087a7a1dd58f51299e258cff 219 SUPERFAMILY SSF161098 13 203 8.63E-42 T 12-10-2018 IPR035906 MetI-like superfamily HW35_09980 4ae70602f2d4e1904728f4d43eedda74 77 Gene3D G3DSA:3.10.290.10 5 71 2.3E-24 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HW35_09980 4ae70602f2d4e1904728f4d43eedda74 77 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 10 69 1.8E-31 T 12-10-2018 IPR014330 RNA-binding S4-related,YaaA HW35_09980 4ae70602f2d4e1904728f4d43eedda74 77 SUPERFAMILY SSF55174 9 73 6.56E-18 T 12-10-2018 HW35_09980 4ae70602f2d4e1904728f4d43eedda74 77 Pfam PF13275 S4 domain 11 70 1.7E-28 T 12-10-2018 HW35_08985 86aa266bb8efc97ba78ec8609e1acee7 299 Pfam PF01551 Peptidase family M23 118 216 2.9E-23 T 12-10-2018 IPR016047 Peptidase M23 HW35_08985 86aa266bb8efc97ba78ec8609e1acee7 299 Gene3D G3DSA:2.70.70.10 75 232 1.8E-48 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_08985 86aa266bb8efc97ba78ec8609e1acee7 299 SUPERFAMILY SSF51261 49 219 1.03E-26 T 12-10-2018 IPR011055 Duplicated hybrid motif HW35_04855 ce4159c1ec9e6f3a95af77c379a906e9 131 Pfam PF05025 RbsD / FucU transport protein family 1 129 3.8E-45 T 12-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 HW35_04855 ce4159c1ec9e6f3a95af77c379a906e9 131 SUPERFAMILY SSF102546 1 131 1.14E-42 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 HW35_04855 ce4159c1ec9e6f3a95af77c379a906e9 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 31.683 T 12-10-2018 IPR023064 D-ribose pyranase GO:0016872 HW35_04855 ce4159c1ec9e6f3a95af77c379a906e9 131 Gene3D G3DSA:3.40.1650.10 8 128 2.7E-37 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 260 33.951 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 Pfam PF02110 Hydroxyethylthiazole kinase family 10 257 7.2E-95 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 PIRSF PIRSF000513 4 268 5.4E-97 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 SUPERFAMILY SSF53613 8 261 2.95E-62 T 12-10-2018 IPR029056 Ribokinase-like HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 Gene3D G3DSA:3.40.1190.20 1 269 6.8E-99 T 12-10-2018 IPR029056 Ribokinase-like HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 1.1E-42 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 1.1E-42 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 1.1E-42 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 163 180 1.1E-42 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 1.1E-42 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 1.1E-42 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00665 820e2e3b968df8a71022e588d06d3d2e 275 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 10 258 1.4E-99 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_06405 53f3258d95e88e215e0284b8bca3e39c 312 Pfam PF01040 UbiA prenyltransferase family 35 264 3.5E-38 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 HW35_06405 53f3258d95e88e215e0284b8bca3e39c 312 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 18 305 19.878 T 12-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 HW35_06405 53f3258d95e88e215e0284b8bca3e39c 312 PIRSF PIRSF005355 14 310 2.3E-86 T 12-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 HW35_06405 53f3258d95e88e215e0284b8bca3e39c 312 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 27 303 2.2E-35 T 12-10-2018 HW35_15470 c35f3211cc6b43ff897b0fc882c87de5 170 Gene3D G3DSA:3.90.1140.10 2 170 3.3E-44 T 12-10-2018 HW35_15470 c35f3211cc6b43ff897b0fc882c87de5 170 Hamap MF_01444 Putative phosphoesterase . 1 168 39.389 T 12-10-2018 IPR022932 Putative phosphoesterase YjcG HW35_15470 c35f3211cc6b43ff897b0fc882c87de5 170 Pfam PF13563 2'-5' RNA ligase superfamily 11 153 3.2E-24 T 12-10-2018 HW35_15470 c35f3211cc6b43ff897b0fc882c87de5 170 SUPERFAMILY SSF55144 1 168 9.42E-33 T 12-10-2018 IPR009097 Cyclic phosphodiesterase HW35_00495 e355aff3e88214689b17a162e5e7d270 144 Pfam PF02050 Flagellar FliJ protein 21 140 1.3E-8 T 12-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 HW35_04165 a529d0058b817315fa0ce27c17c02b90 264 Pfam PF11079 Bacterial protein YqhG of unknown function 1 259 1.5E-126 T 12-10-2018 IPR024562 Uncharacterised protein family YqhG HW35_04165 a529d0058b817315fa0ce27c17c02b90 264 ProDom PD123329 YQHG BH2818 1 259 5.0E-95 T 12-10-2018 IPR024562 Uncharacterised protein family YqhG HW35_13760 01c537e8aae34b2288c2557186ed72a1 515 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 7 282 3.4E-65 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 HW35_13760 01c537e8aae34b2288c2557186ed72a1 515 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 334 495 1.5E-50 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HW35_13760 01c537e8aae34b2288c2557186ed72a1 515 Gene3D G3DSA:3.20.130.10 311 496 4.5E-65 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 HW35_13760 01c537e8aae34b2288c2557186ed72a1 515 SUPERFAMILY SSF117457 326 495 5.75E-52 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 HW35_13760 01c537e8aae34b2288c2557186ed72a1 515 PIRSF PIRSF001394 1 514 1.4E-197 T 12-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 HW35_13760 01c537e8aae34b2288c2557186ed72a1 515 Pfam PF05681 Fumarate hydratase (Fumerase) 8 283 3.7E-74 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 HW35_13760 01c537e8aae34b2288c2557186ed72a1 515 Pfam PF05683 Fumarase C-terminus 310 497 3.4E-61 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HW35_13515 2bff67fcda9cf04304df941c43c169dd 149 SUPERFAMILY SSF55781 8 132 5.1E-12 T 12-10-2018 HW35_13515 2bff67fcda9cf04304df941c43c169dd 149 Pfam PF13185 GAF domain 9 130 1.2E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 HW35_13515 2bff67fcda9cf04304df941c43c169dd 149 Gene3D G3DSA:3.30.450.40 9 145 1.3E-28 T 12-10-2018 IPR029016 GAF-like domain superfamily HW35_10390 4467255a1b7e3177c35e0ff181570ebe 278 SUPERFAMILY SSF51717 6 272 2.09E-101 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_10390 4467255a1b7e3177c35e0ff181570ebe 278 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 55 68 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_10390 4467255a1b7e3177c35e0ff181570ebe 278 Gene3D G3DSA:3.20.20.20 1 275 4.0E-113 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_10390 4467255a1b7e3177c35e0ff181570ebe 278 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 21 270 7.2E-99 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 HW35_10390 4467255a1b7e3177c35e0ff181570ebe 278 Pfam PF00809 Pterin binding enzyme 22 255 8.6E-84 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_10390 4467255a1b7e3177c35e0ff181570ebe 278 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 21 36 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HW35_00040 0ae7f16ba05943a642f25038dd9758ff 572 Pfam PF00005 ABC transporter 349 498 1.3E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_00040 0ae7f16ba05943a642f25038dd9758ff 572 Gene3D G3DSA:1.20.1560.10 1 315 9.5E-85 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_00040 0ae7f16ba05943a642f25038dd9758ff 572 Gene3D G3DSA:3.40.50.300 329 572 7.2E-95 T 12-10-2018 HW35_00040 0ae7f16ba05943a642f25038dd9758ff 572 SUPERFAMILY SSF52540 322 569 1.74E-94 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_00040 0ae7f16ba05943a642f25038dd9758ff 572 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_00040 0ae7f16ba05943a642f25038dd9758ff 572 SUPERFAMILY SSF90123 4 319 1.31E-79 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HW35_00040 0ae7f16ba05943a642f25038dd9758ff 572 SMART SM00382 358 544 2.5E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_00040 0ae7f16ba05943a642f25038dd9758ff 572 Pfam PF00664 ABC transporter transmembrane region 17 286 2.5E-57 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 Gene3D G3DSA:1.10.540.10 1 120 1.3E-49 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 2.6E-52 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 5.9E-45 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 3.4E-27 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 PIRSF PIRSF016578 3 377 2.3E-16 T 12-10-2018 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 Gene3D G3DSA:1.20.140.10 235 379 1.5E-56 T 12-10-2018 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 SUPERFAMILY SSF47203 227 378 1.27E-59 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 SUPERFAMILY SSF56645 1 242 8.64E-97 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 Gene3D G3DSA:2.40.110.10 121 234 7.5E-47 T 12-10-2018 HW35_09270 3690da4ad51f79d639fc56be1b13bba0 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HW35_17030 6a5c406b10d94a0da474053dc2dbfcca 151 SUPERFAMILY SSF158622 4 123 7.98E-37 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily HW35_17030 6a5c406b10d94a0da474053dc2dbfcca 151 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 10 113 5.3E-25 T 12-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA HW35_17030 6a5c406b10d94a0da474053dc2dbfcca 151 PIRSF PIRSF021287 1 123 9.7E-51 T 12-10-2018 IPR016783 Biofilm formation YmcA HW35_17030 6a5c406b10d94a0da474053dc2dbfcca 151 Gene3D G3DSA:1.20.1500.10 1 124 8.9E-38 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily HW35_14640 8d6fb2d6bc1f9ec78ac24dc0915010c5 129 Pfam PF08388 Group II intron, maturase-specific domain 1 70 1.1E-19 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_15235 a8f3f3a6726523b890255b7152da4e99 240 Gene3D G3DSA:3.40.50.1820 52 224 4.5E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_15235 a8f3f3a6726523b890255b7152da4e99 240 SUPERFAMILY SSF53474 52 146 7.56E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold HW35_15215 8f49024e3ebe4fde213e4836356c2317 176 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 8 137 2.1E-27 T 12-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 HW35_15215 8f49024e3ebe4fde213e4836356c2317 176 Gene3D G3DSA:3.40.50.300 7 174 1.3E-48 T 12-10-2018 HW35_15215 8f49024e3ebe4fde213e4836356c2317 176 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 8 137 5.2E-31 T 12-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 HW35_15215 8f49024e3ebe4fde213e4836356c2317 176 SUPERFAMILY SSF52540 6 145 8.39E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_03635 6bb8bf3cfa3453ccd964ceba702440a9 116 Gene3D G3DSA:3.40.630.30 4 110 1.4E-12 T 12-10-2018 HW35_03635 6bb8bf3cfa3453ccd964ceba702440a9 116 Pfam PF00583 Acetyltransferase (GNAT) family 29 112 2.3E-8 T 12-10-2018 IPR000182 GNAT domain HW35_03635 6bb8bf3cfa3453ccd964ceba702440a9 116 SUPERFAMILY SSF55729 6 95 2.7E-11 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_05225 79ee78d9e058238aacd06e965b9ce84d 258 SUPERFAMILY SSF69618 9 251 3.92E-63 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05225 79ee78d9e058238aacd06e965b9ce84d 258 Pfam PF02602 Uroporphyrinogen-III synthase HemD 24 247 1.4E-60 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_05225 79ee78d9e058238aacd06e965b9ce84d 258 Gene3D G3DSA:3.40.50.10090 41 170 2.0E-30 T 12-10-2018 HW35_05225 79ee78d9e058238aacd06e965b9ce84d 258 Gene3D G3DSA:3.40.50.10090 176 258 3.8E-14 T 12-10-2018 HW35_06045 b1dd73d6e0a8da2ed97b15002d2a152b 472 Gene3D G3DSA:3.30.70.360 209 297 3.0E-169 T 12-10-2018 HW35_06045 b1dd73d6e0a8da2ed97b15002d2a152b 472 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 15 467 1.8E-174 T 12-10-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 HW35_06045 b1dd73d6e0a8da2ed97b15002d2a152b 472 Gene3D G3DSA:3.30.70.360 188 386 3.0E-169 T 12-10-2018 HW35_06045 b1dd73d6e0a8da2ed97b15002d2a152b 472 SUPERFAMILY SSF55031 188 384 2.44E-48 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain HW35_06045 b1dd73d6e0a8da2ed97b15002d2a152b 472 Pfam PF01546 Peptidase family M20/M25/M40 88 468 1.0E-31 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 HW35_06045 b1dd73d6e0a8da2ed97b15002d2a152b 472 Gene3D G3DSA:3.40.630.10 17 470 3.0E-169 T 12-10-2018 HW35_06045 b1dd73d6e0a8da2ed97b15002d2a152b 472 SUPERFAMILY SSF53187 6 471 1.17E-64 T 12-10-2018 HW35_12840 9706e9d6bac676abe5bc13461ddd8a74 186 SUPERFAMILY SSF56784 2 179 3.45E-22 T 12-10-2018 IPR036412 HAD-like superfamily HW35_12840 9706e9d6bac676abe5bc13461ddd8a74 186 PIRSF PIRSF021362 1 186 4.2E-56 T 12-10-2018 IPR009206 Nucleotidase, putative HW35_12840 9706e9d6bac676abe5bc13461ddd8a74 186 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 4 185 1.5E-14 T 12-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 HW35_12840 9706e9d6bac676abe5bc13461ddd8a74 186 Gene3D G3DSA:3.40.50.1000 1 173 2.1E-28 T 12-10-2018 IPR023214 HAD superfamily HW35_13765 6aa03832d0a2e749a9d68b39184676b6 263 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 27 250 1.0E-105 T 12-10-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA HW35_13765 6aa03832d0a2e749a9d68b39184676b6 263 Gene3D G3DSA:3.20.20.370 15 255 2.3E-87 T 12-10-2018 HW35_13765 6aa03832d0a2e749a9d68b39184676b6 263 SUPERFAMILY SSF88713 41 250 8.29E-68 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HW35_13765 6aa03832d0a2e749a9d68b39184676b6 263 Pfam PF01522 Polysaccharide deacetylase 58 180 3.5E-37 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HW35_15715 2b2e8922475948fd8773287cce6e1a55 100 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 69 80 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HW35_15715 2b2e8922475948fd8773287cce6e1a55 100 SUPERFAMILY SSF54862 29 97 5.93E-17 T 12-10-2018 HW35_15715 2b2e8922475948fd8773287cce6e1a55 100 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 23 94 6.0E-11 T 12-10-2018 HW35_15715 2b2e8922475948fd8773287cce6e1a55 100 PIRSF PIRSF036548 6 100 1.2E-20 T 12-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 HW35_15715 2b2e8922475948fd8773287cce6e1a55 100 Gene3D G3DSA:3.30.70.20 10 94 2.1E-16 T 12-10-2018 HW35_07975 a06c102e342af48abf2845f80d0180a2 480 Pfam PF04932 O-Antigen ligase 238 413 8.7E-22 T 12-10-2018 IPR007016 O-antigen ligase-related HW35_15815 60f22e1d43919a5d5e55973dcb6917af 281 Gene3D G3DSA:3.30.420.10 94 273 2.8E-6 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_15815 60f22e1d43919a5d5e55973dcb6917af 281 Pfam PF13276 HTH-like domain 35 90 1.1E-10 T 12-10-2018 IPR025948 HTH-like domain HW35_15815 60f22e1d43919a5d5e55973dcb6917af 281 Pfam PF00665 Integrase core domain 121 233 5.6E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_15815 60f22e1d43919a5d5e55973dcb6917af 281 SUPERFAMILY SSF53098 119 271 2.53E-24 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_13715 60f22e1d43919a5d5e55973dcb6917af 281 Gene3D G3DSA:3.30.420.10 94 273 2.8E-6 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_13715 60f22e1d43919a5d5e55973dcb6917af 281 Pfam PF13276 HTH-like domain 35 90 1.1E-10 T 12-10-2018 IPR025948 HTH-like domain HW35_13715 60f22e1d43919a5d5e55973dcb6917af 281 Pfam PF00665 Integrase core domain 121 233 5.6E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_13715 60f22e1d43919a5d5e55973dcb6917af 281 SUPERFAMILY SSF53098 119 271 2.53E-24 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_07950 60f22e1d43919a5d5e55973dcb6917af 281 Gene3D G3DSA:3.30.420.10 94 273 2.8E-6 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_07950 60f22e1d43919a5d5e55973dcb6917af 281 Pfam PF13276 HTH-like domain 35 90 1.1E-10 T 12-10-2018 IPR025948 HTH-like domain HW35_07950 60f22e1d43919a5d5e55973dcb6917af 281 Pfam PF00665 Integrase core domain 121 233 5.6E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_07950 60f22e1d43919a5d5e55973dcb6917af 281 SUPERFAMILY SSF53098 119 271 2.53E-24 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_15515 60f22e1d43919a5d5e55973dcb6917af 281 Gene3D G3DSA:3.30.420.10 94 273 2.8E-6 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_15515 60f22e1d43919a5d5e55973dcb6917af 281 Pfam PF13276 HTH-like domain 35 90 1.1E-10 T 12-10-2018 IPR025948 HTH-like domain HW35_15515 60f22e1d43919a5d5e55973dcb6917af 281 Pfam PF00665 Integrase core domain 121 233 5.6E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_15515 60f22e1d43919a5d5e55973dcb6917af 281 SUPERFAMILY SSF53098 119 271 2.53E-24 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_10850 166f20f658d63a961dbb4141068611f1 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10850 166f20f658d63a961dbb4141068611f1 120 Pfam PF01196 Ribosomal protein L17 16 120 1.1E-39 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10850 166f20f658d63a961dbb4141068611f1 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 120 7.4E-49 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10850 166f20f658d63a961dbb4141068611f1 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 28.959 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10850 166f20f658d63a961dbb4141068611f1 120 Gene3D G3DSA:3.90.1030.10 1 120 5.8E-51 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10850 166f20f658d63a961dbb4141068611f1 120 SUPERFAMILY SSF64263 2 120 5.1E-45 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_02820 e4e49e444643911d5750b23a58d3874c 198 Pfam PF12389 Camelysin metallo-endopeptidase 2 196 1.6E-92 T 12-10-2018 IPR022121 Peptidase M73, camelysin HW35_02820 e4e49e444643911d5750b23a58d3874c 198 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 11 44 7.2E-10 T 12-10-2018 IPR023833 Signal peptide, camelysin HW35_01270 54624c6eefbc8b0226faf0e75676363c 206 Pfam PF13739 Domain of unknown function (DUF4163) 21 97 4.8E-8 T 12-10-2018 IPR025303 Deacetylase PdaC HW35_01270 54624c6eefbc8b0226faf0e75676363c 206 Pfam PF11738 Protein of unknown function (DUF3298) 115 185 2.4E-17 T 12-10-2018 IPR021729 Domain of unknown function DUF3298 HW35_01270 54624c6eefbc8b0226faf0e75676363c 206 Gene3D G3DSA:3.90.640.20 113 198 5.0E-19 T 12-10-2018 IPR037126 PdaC/RsiV-like superfamily HW35_01270 54624c6eefbc8b0226faf0e75676363c 206 Gene3D G3DSA:3.30.565.40 16 111 2.9E-14 T 12-10-2018 HW35_09715 789c186d1bc03781fdacc385cf9a49b8 228 Pfam PF03070 TENA/THI-4/PQQC family 9 215 8.8E-49 T 12-10-2018 IPR004305 Thiaminase-2/PQQC HW35_09715 789c186d1bc03781fdacc385cf9a49b8 228 SUPERFAMILY SSF48613 1 214 5.88E-67 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 HW35_09715 789c186d1bc03781fdacc385cf9a49b8 228 Gene3D G3DSA:1.20.910.10 1 226 1.8E-68 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 HW35_09715 789c186d1bc03781fdacc385cf9a49b8 228 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 215 4.8E-58 T 12-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 HW35_10165 4e5f99f8dcb82f07746d5086e03e5213 275 Pfam PF04468 PSP1 C-terminal conserved region 61 146 6.5E-32 T 12-10-2018 IPR007557 PSP1, C-terminal HW35_17505 298fecec2848b76aa573540104997237 608 Pfam PF13520 Amino acid permease 29 445 1.9E-30 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HW35_17505 298fecec2848b76aa573540104997237 608 Gene3D G3DSA:1.20.1740.10 48 466 1.4E-20 T 12-10-2018 HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 SUPERFAMILY SSF53822 61 320 1.9E-56 T 12-10-2018 IPR028082 Periplasmic binding protein-like I HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.7E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.7E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 Gene3D G3DSA:1.10.260.40 3 59 1.7E-21 T 12-10-2018 HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.1E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 Gene3D G3DSA:3.40.50.2300 158 285 1.8E-56 T 12-10-2018 HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 SMART SM00354 1 71 2.8E-32 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 Gene3D G3DSA:3.40.50.2300 60 294 1.8E-56 T 12-10-2018 HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 SUPERFAMILY SSF47413 1 59 5.16E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 Pfam PF13377 Periplasmic binding protein-like domain 167 320 5.7E-27 T 12-10-2018 HW35_12600 78040a84fe112affd6ca9f0f2d37ec67 320 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 HW35_13470 4f032b05414dc7cd83c2fe53daa42d33 346 SUPERFAMILY SSF103501 44 266 2.09E-19 T 12-10-2018 IPR036197 NarG-like superfamily HW35_00710 ea08d7eb5ddf5f49827bdf82f92c8ee1 243 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 1 243 40.787 T 12-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 HW35_00710 ea08d7eb5ddf5f49827bdf82f92c8ee1 243 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 1 235 6.0E-52 T 12-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 HW35_02685 4783770961d9b244f4301ef1cb5a62f6 256 Pfam PF07070 SpoOM protein 4 214 1.3E-80 T 12-10-2018 IPR009776 Sporulation stage 0, protein M HW35_09365 a6f91e5bf181444228cc9a6cd44f8abd 241 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 2 77 1.5E-43 T 12-10-2018 IPR014243 Transcription factor, RsfA HW35_07370 5bb422390820f49db350ed1974216b5c 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.9E-14 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HW35_07370 5bb422390820f49db350ed1974216b5c 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.9E-14 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HW35_07370 5bb422390820f49db350ed1974216b5c 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 1.9E-14 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HW35_07370 5bb422390820f49db350ed1974216b5c 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 75 3.7E-24 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HW35_07370 5bb422390820f49db350ed1974216b5c 77 Pfam PF03840 Preprotein translocase SecG subunit 4 74 1.5E-22 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HW35_16170 4708b413ea5b79e088883009a7e97dcc 90 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 2.7E-33 T 12-10-2018 IPR016979 Protein of unknown function DUF2129 HW35_16170 4708b413ea5b79e088883009a7e97dcc 90 PIRSF PIRSF031653 1 90 6.1E-36 T 12-10-2018 IPR016979 Protein of unknown function DUF2129 HW35_16170 4708b413ea5b79e088883009a7e97dcc 90 Hamap MF_01126 UPF0298 protein . 1 78 22.908 T 12-10-2018 IPR016979 Protein of unknown function DUF2129 HW35_17075 989b467f626b86419c85901be9e38c15 202 Pfam PF01613 Flavin reductase like domain 23 168 3.8E-24 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 HW35_17075 989b467f626b86419c85901be9e38c15 202 SUPERFAMILY SSF50475 9 198 2.7E-45 T 12-10-2018 HW35_17075 989b467f626b86419c85901be9e38c15 202 SMART SM00903 20 175 3.9E-24 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 HW35_17075 989b467f626b86419c85901be9e38c15 202 Gene3D G3DSA:2.30.110.10 2 202 2.0E-66 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 HW35_15220 9109dbbd36176756432a33093df4fbcc 59 Pfam PF14168 YjzC-like protein 1 55 7.0E-28 T 12-10-2018 IPR025549 YjzC-like protein HW35_14475 a6f7373be3f02dacfc419eed39e72561 163 Pfam PF13730 Helix-turn-helix domain 41 88 3.5E-6 T 12-10-2018 HW35_14475 a6f7373be3f02dacfc419eed39e72561 163 SUPERFAMILY SSF46785 62 125 4.68E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_14475 a6f7373be3f02dacfc419eed39e72561 163 Gene3D G3DSA:1.10.10.10 14 130 2.6E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_17035 4a16960a9b8c14817531594a286ecc34 181 Pfam PF10628 Outer spore coat protein E (CotE) 3 175 7.0E-69 T 12-10-2018 IPR018901 Spore coat protein CotE HW35_07605 8aebbf4bbab428c922d41b5fcb257b1f 297 SUPERFAMILY SSF52540 11 165 1.98E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_07605 8aebbf4bbab428c922d41b5fcb257b1f 297 Gene3D G3DSA:3.40.50.300 7 175 4.8E-5 T 12-10-2018 HW35_07605 8aebbf4bbab428c922d41b5fcb257b1f 297 PIRSF PIRSF005052 9 294 4.5E-108 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 HW35_07605 8aebbf4bbab428c922d41b5fcb257b1f 297 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 9 291 41.898 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 HW35_07605 8aebbf4bbab428c922d41b5fcb257b1f 297 Pfam PF03668 P-loop ATPase protein family 9 292 2.2E-131 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 HW35_15765 1d4154e7b1c26e62334f22f50d6c12dc 203 Pfam PF02517 CAAX protease self-immunity 104 195 2.6E-16 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 HW35_08405 121fec68abd99dd4fa1045a93fad4b3d 332 Pfam PF03961 Flagellar Assembly Protein A 146 330 1.1E-28 T 12-10-2018 IPR005646 Flagellar assembly protein A HW35_08390 4c772feeb37d80642fc26e8b1ad9d86c 326 SUPERFAMILY SSF53613 1 311 9.67E-89 T 12-10-2018 IPR029056 Ribokinase-like HW35_08390 4c772feeb37d80642fc26e8b1ad9d86c 326 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HW35_08390 4c772feeb37d80642fc26e8b1ad9d86c 326 Pfam PF00294 pfkB family carbohydrate kinase 5 303 2.7E-65 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB HW35_08390 4c772feeb37d80642fc26e8b1ad9d86c 326 Gene3D G3DSA:3.40.1190.20 4 315 2.8E-94 T 12-10-2018 IPR029056 Ribokinase-like HW35_12940 c4d188aa69cb7973823548e02190236b 150 Pfam PF10027 Predicted integral membrane protein (DUF2269) 7 149 2.7E-24 T 12-10-2018 IPR018729 Protein of unknown function DUF2269, transmembrane HW35_14440 89a8098fc78fce089bff9ed135295508 67 Gene3D G3DSA:1.10.260.40 2 66 2.4E-18 T 12-10-2018 HW35_14440 89a8098fc78fce089bff9ed135295508 67 SMART SM00530 6 61 1.9E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_14440 89a8098fc78fce089bff9ed135295508 67 Pfam PF01381 Helix-turn-helix 7 58 3.1E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HW35_14440 89a8098fc78fce089bff9ed135295508 67 SUPERFAMILY SSF47413 1 66 7.17E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_13025 b0b828da09159bec51f3364c83d8d2da 334 Gene3D G3DSA:3.20.20.140 1 330 9.8E-105 T 12-10-2018 HW35_13025 b0b828da09159bec51f3364c83d8d2da 334 SUPERFAMILY SSF51556 1 330 1.87E-90 T 12-10-2018 IPR032466 Metal-dependent hydrolase HW35_13025 b0b828da09159bec51f3364c83d8d2da 334 Pfam PF04909 Amidohydrolase 3 327 5.0E-57 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 HW35_10270 b1265e47f1980f65348d20c31b4ae3e3 211 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 3 179 24.752 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 HW35_10270 b1265e47f1980f65348d20c31b4ae3e3 211 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 5 178 9.6E-51 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 HW35_10270 b1265e47f1980f65348d20c31b4ae3e3 211 SUPERFAMILY SSF50715 2 185 9.42E-48 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HW35_10270 b1265e47f1980f65348d20c31b4ae3e3 211 Pfam PF01386 Ribosomal L25p family 5 91 1.1E-20 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 HW35_10270 b1265e47f1980f65348d20c31b4ae3e3 211 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 181 1.9E-23 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain HW35_10270 b1265e47f1980f65348d20c31b4ae3e3 211 Gene3D G3DSA:2.40.240.10 2 94 3.5E-26 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HW35_10270 b1265e47f1980f65348d20c31b4ae3e3 211 Gene3D G3DSA:2.170.120.20 97 188 3.1E-24 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal HW35_10270 b1265e47f1980f65348d20c31b4ae3e3 211 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 5 94 2.0E-18 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 HW35_01700 476483ce05a28de86d358e5c347ee7a4 70 Pfam PF10676 Spore germination protein gerPA/gerPF 5 67 2.7E-18 T 12-10-2018 IPR019618 Spore germination protein GerPA/GerPF HW35_12065 c25e80e52a817653783b1ee2160ce5f0 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 252 1.3E-59 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HW35_12065 c25e80e52a817653783b1ee2160ce5f0 329 Gene3D G3DSA:3.40.50.720 3 264 6.8E-128 T 12-10-2018 HW35_12065 c25e80e52a817653783b1ee2160ce5f0 329 SUPERFAMILY SSF51735 1 328 1.25E-99 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_12065 c25e80e52a817653783b1ee2160ce5f0 329 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 326 3.5E-135 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 HW35_12065 c25e80e52a817653783b1ee2160ce5f0 329 Gene3D G3DSA:3.90.25.10 185 320 6.8E-128 T 12-10-2018 HW35_12770 1dc46a9dce26d913d35532d7ecbb37bf 72 Pfam PF03621 MbtH-like protein 1 53 2.8E-24 T 12-10-2018 IPR005153 MbtH-like domain HW35_12770 1dc46a9dce26d913d35532d7ecbb37bf 72 SUPERFAMILY SSF160582 1 69 8.76E-29 T 12-10-2018 IPR038020 MbtH-like domain superfamily HW35_12770 1dc46a9dce26d913d35532d7ecbb37bf 72 SMART SM00923 3 53 6.2E-24 T 12-10-2018 IPR005153 MbtH-like domain HW35_12770 1dc46a9dce26d913d35532d7ecbb37bf 72 Gene3D G3DSA:3.90.820.10 1 70 4.1E-31 T 12-10-2018 HW35_07805 b11a6829d6af9f699fcfa21a30a7d342 101 SUPERFAMILY SSF47240 2 86 2.57E-28 T 12-10-2018 IPR009078 Ferritin-like superfamily HW35_07805 b11a6829d6af9f699fcfa21a30a7d342 101 Pfam PF05067 Manganese containing catalase 2 85 1.0E-23 T 12-10-2018 IPR007760 Manganese catalase HW35_07805 b11a6829d6af9f699fcfa21a30a7d342 101 Gene3D G3DSA:1.20.1260.130 3 98 4.4E-29 T 12-10-2018 HW35_16415 38aeee0a08c57bff02bdfc304410c985 149 Hamap MF_01197 Cell division protein SepF [sepF]. 1 139 17.973 T 12-10-2018 IPR023052 Cell division protein SepF GO:0090529 HW35_16415 38aeee0a08c57bff02bdfc304410c985 149 Pfam PF04472 Cell division protein SepF 60 131 1.7E-27 T 12-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 HW35_16415 38aeee0a08c57bff02bdfc304410c985 149 Gene3D G3DSA:3.30.110.150 53 149 7.8E-31 T 12-10-2018 IPR038594 SepF-like superfamily HW35_03525 d0ed936769bffbec0a487320a2323e49 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 6.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 HW35_03525 d0ed936769bffbec0a487320a2323e49 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 6.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 HW35_03525 d0ed936769bffbec0a487320a2323e49 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 6.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 HW35_03525 d0ed936769bffbec0a487320a2323e49 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 3.4E-21 T 12-10-2018 HW35_03525 d0ed936769bffbec0a487320a2323e49 82 Gene3D G3DSA:3.30.70.20 2 82 1.9E-36 T 12-10-2018 HW35_03525 d0ed936769bffbec0a487320a2323e49 82 SUPERFAMILY SSF54862 4 73 1.8E-13 T 12-10-2018 HW35_13665 e15f97a6df105e4a83921cd9267d224e 124 Pfam PF09350 Domain of unknown function (DUF1992) 7 73 1.9E-22 T 12-10-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain HW35_17485 6f84ad2e1c9cd7c8537fc90bc1d21d4e 356 Pfam PF01384 Phosphate transporter family 17 307 7.7E-51 T 12-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 HW35_14430 4a5624c8ed7fa0fe884d613f83fa5892 115 Gene3D G3DSA:1.10.10.60 17 114 1.6E-7 T 12-10-2018 HW35_14430 4a5624c8ed7fa0fe884d613f83fa5892 115 Pfam PF13022 Helix-turn-helix of insertion element transposase 14 107 6.9E-9 T 12-10-2018 IPR024978 Homeodomain, phBC6A51-type HW35_03985 5e9abaf775c557fa7fdbbfa2bfc20a8c 135 Pfam PF03780 Asp23 family, cell envelope-related function 17 121 5.3E-37 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 HW35_15020 df3efcda3d28bb79014f0f05c9e1b851 102 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 5 97 1.7E-22 T 12-10-2018 IPR008407 Branched-chain amino acid transport, AzlD HW35_03640 55799a2329b2c0c88aede0a272196ebd 288 Pfam PF06207 Protein of unknown function (DUF1002) 33 250 1.9E-81 T 12-10-2018 IPR009343 Protein of unknown function DUF1002 HW35_03480 6fa87fd4bc7400692a72904015b7b4ef 193 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 82 6.4E-18 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA HW35_03480 6fa87fd4bc7400692a72904015b7b4ef 193 Pfam PF05389 Negative regulator of genetic competence (MecA) 104 188 1.5E-11 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA HW35_03480 6fa87fd4bc7400692a72904015b7b4ef 193 Gene3D G3DSA:3.30.70.1950 104 193 1.2E-23 T 12-10-2018 IPR038471 MecA, C-terminal domain superfamily HW35_15340 4ee4237a67979acb4818f75035cd60cd 222 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 217 3.2E-48 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA HW35_15340 4ee4237a67979acb4818f75035cd60cd 222 Gene3D G3DSA:3.30.70.1950 124 222 5.2E-28 T 12-10-2018 IPR038471 MecA, C-terminal domain superfamily HW35_15340 4ee4237a67979acb4818f75035cd60cd 222 PIRSF PIRSF029008 1 222 1.6E-72 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA HW35_15340 4ee4237a67979acb4818f75035cd60cd 222 Hamap MF_01124 Adapter protein MecA [mecA]. 1 221 27.21 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA HW35_11885 579cb864b859199c31904e0d00613aa0 161 Pfam PF15978 Tn7-like transposition protein D 71 161 3.9E-18 T 12-10-2018 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl HW35_09710 9e69f250bc5ffd1183725ec65a93ec2d 198 PIRSF PIRSF037394 1 190 1.9E-64 T 12-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted HW35_09710 9e69f250bc5ffd1183725ec65a93ec2d 198 Pfam PF09819 ABC-type cobalt transport system, permease component 6 124 4.5E-39 T 12-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted HW35_14300 76945c60ffcc590fbab8844bed555b90 261 Pfam PF06182 ABC-2 family transporter protein 34 260 9.4E-57 T 12-10-2018 IPR010390 Protein of unknown function DUF990 HW35_11190 ea813964a02117fac462e4588f2e55a9 110 Gene3D G3DSA:3.40.50.2300 1 109 1.3E-36 T 12-10-2018 HW35_11190 ea813964a02117fac462e4588f2e55a9 110 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 99 2.7E-21 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HW35_11190 ea813964a02117fac462e4588f2e55a9 110 SUPERFAMILY SSF52794 4 106 4.45E-34 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 HW35_06905 6f6bb5171dc7e353e8845fc32af5ca81 107 Pfam PF14068 Putative membrane protein 8 107 3.7E-43 T 12-10-2018 IPR025917 Putative membrane protein YuiB HW35_13185 28a74e7684ce51cd381465a6995e68ac 288 Gene3D G3DSA:2.160.20.120 30 251 3.7E-8 T 12-10-2018 HW35_13185 28a74e7684ce51cd381465a6995e68ac 288 Pfam PF13349 Putative adhesin 45 287 9.7E-43 T 12-10-2018 IPR025164 Putative adhesin HW35_10805 6435c14c0bacbbbcecfa6e63063df84f 60 Gene3D G3DSA:3.30.1390.20 1 59 9.2E-28 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily HW35_10805 6435c14c0bacbbbcecfa6e63063df84f 60 Pfam PF00327 Ribosomal protein L30p/L7e 5 55 5.3E-22 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HW35_10805 6435c14c0bacbbbcecfa6e63063df84f 60 SUPERFAMILY SSF55129 3 59 2.35E-21 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily HW35_10805 6435c14c0bacbbbcecfa6e63063df84f 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 7 59 4.2E-27 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10805 6435c14c0bacbbbcecfa6e63063df84f 60 PIRSF PIRSF002211 1 60 8.6E-30 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_10805 6435c14c0bacbbbcecfa6e63063df84f 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 12-10-2018 IPR018038 Ribosomal protein L30, conserved site HW35_10805 6435c14c0bacbbbcecfa6e63063df84f 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 19.864 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_04175 7660866a19513be5679300291be58d51 126 Pfam PF14173 ComG operon protein 7 32 124 8.2E-10 T 12-10-2018 IPR020372 Competence operon G protein 7, ComGG HW35_04175 7660866a19513be5679300291be58d51 126 ProDom PD078266 COMPETENCE COMGG LATE MACHINERY OPERON DNA THE PART PRECURSOR PROBABLY 4 123 0.001 T 12-10-2018 IPR020372 Competence operon G protein 7, ComGG HW35_15825 789411794864887af35766b4f9e7faf8 159 Pfam PF14177 YkyB-like protein 15 155 4.9E-63 T 12-10-2018 IPR025552 YkyB-like protein HW35_11360 70da5d0f58c4cee110de7df10f807cd4 104 Gene3D G3DSA:1.10.3730.20 1 104 9.4E-23 T 12-10-2018 HW35_11360 70da5d0f58c4cee110de7df10f807cd4 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.3E-25 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 HW35_11360 70da5d0f58c4cee110de7df10f807cd4 104 SUPERFAMILY SSF103481 6 103 5.75E-18 T 12-10-2018 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 SUPERFAMILY SSF53738 29 236 3.53E-48 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 SUPERFAMILY SSF53738 208 312 2.27E-20 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 312 1.0E-23 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 SUPERFAMILY SSF55957 446 570 4.58E-15 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 Gene3D G3DSA:3.40.120.10 209 325 1.4E-23 T 12-10-2018 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 SUPERFAMILY SSF53738 304 454 2.79E-32 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 5.6E-6 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 5.6E-6 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 Gene3D G3DSA:3.40.120.10 326 452 4.0E-38 T 12-10-2018 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 324 451 5.3E-23 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 182 1.3E-42 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 506 548 3.0E-10 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 Gene3D G3DSA:3.40.120.10 33 189 3.3E-47 T 12-10-2018 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HW35_14695 536d724b06c12bfe7b5dc3d80abc5ca8 579 Gene3D G3DSA:3.30.310.50 474 569 8.6E-10 T 12-10-2018 HW35_02730 4bebd2e7c24e4e5bb84cfeed9d87483e 422 SUPERFAMILY SSF55031 203 311 3.59E-17 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain HW35_02730 4bebd2e7c24e4e5bb84cfeed9d87483e 422 SUPERFAMILY SSF53187 8 419 8.29E-61 T 12-10-2018 HW35_02730 4bebd2e7c24e4e5bb84cfeed9d87483e 422 Pfam PF01546 Peptidase family M20/M25/M40 97 415 5.6E-39 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 HW35_02730 4bebd2e7c24e4e5bb84cfeed9d87483e 422 Gene3D G3DSA:3.30.70.360 204 330 2.9E-142 T 12-10-2018 HW35_02730 4bebd2e7c24e4e5bb84cfeed9d87483e 422 Gene3D G3DSA:3.40.630.10 27 419 2.9E-142 T 12-10-2018 HW35_02730 4bebd2e7c24e4e5bb84cfeed9d87483e 422 Pfam PF07687 Peptidase dimerisation domain 202 314 2.9E-19 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain HW35_02730 4bebd2e7c24e4e5bb84cfeed9d87483e 422 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 21 406 1.8E-118 T 12-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase HW35_16235 6e1b6146068ac1b6f9538878e1a1c30a 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 239 1.5E-32 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 HW35_16235 6e1b6146068ac1b6f9538878e1a1c30a 256 Gene3D G3DSA:3.90.226.10 3 254 7.9E-49 T 12-10-2018 HW35_16235 6e1b6146068ac1b6f9538878e1a1c30a 256 SUPERFAMILY SSF52096 7 251 2.02E-47 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HW35_04115 1c656843f265f14ac91b2f4aaa390e5f 189 Pfam PF06042 Nucleotidyltransferase 29 187 2.5E-54 T 12-10-2018 IPR009267 Putative nucleotidyltransferase HW35_08150 9637dea99a299894a6fc8d92c39dbaae 423 PRINTS PR00173 Glutamate-aspartate symporter signature 145 167 7.1E-19 T 12-10-2018 HW35_08150 9637dea99a299894a6fc8d92c39dbaae 423 PRINTS PR00173 Glutamate-aspartate symporter signature 357 377 7.1E-19 T 12-10-2018 HW35_08150 9637dea99a299894a6fc8d92c39dbaae 423 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 7.1E-19 T 12-10-2018 HW35_08150 9637dea99a299894a6fc8d92c39dbaae 423 PRINTS PR00173 Glutamate-aspartate symporter signature 192 211 7.1E-19 T 12-10-2018 HW35_08150 9637dea99a299894a6fc8d92c39dbaae 423 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 7.1E-19 T 12-10-2018 HW35_08150 9637dea99a299894a6fc8d92c39dbaae 423 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 7.1E-19 T 12-10-2018 HW35_08150 9637dea99a299894a6fc8d92c39dbaae 423 Gene3D G3DSA:1.10.3860.10 2 407 2.0E-84 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 HW35_08150 9637dea99a299894a6fc8d92c39dbaae 423 Pfam PF00375 Sodium:dicarboxylate symporter family 10 402 3.6E-99 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 HW35_08150 9637dea99a299894a6fc8d92c39dbaae 423 SUPERFAMILY SSF118215 9 402 2.88E-85 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 HW35_06885 1203aaf0866758b4ded517e89de0a5b2 126 SUPERFAMILY SSF54637 6 126 1.35E-29 T 12-10-2018 IPR029069 HotDog domain superfamily HW35_06885 1203aaf0866758b4ded517e89de0a5b2 126 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 6 121 1.5E-37 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 HW35_06885 1203aaf0866758b4ded517e89de0a5b2 126 Gene3D G3DSA:3.10.129.10 1 126 8.0E-52 T 12-10-2018 HW35_06885 1203aaf0866758b4ded517e89de0a5b2 126 Pfam PF03061 Thioesterase superfamily 36 114 2.9E-15 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 HW35_02750 0533cb2655b821616152743eb919b3b6 453 Pfam PF02386 Cation transport protein 26 433 2.8E-63 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 HW35_14690 4fa8b553c782e6f9dd9bed6b2e610a7b 132 ProDom PD081567 YHCU 1 109 2.0E-17 T 12-10-2018 IPR020355 Uncharacterised protein family YhcU HW35_14690 4fa8b553c782e6f9dd9bed6b2e610a7b 132 Pfam PF17326 Family of unknown function (DUF5365) 1 114 3.0E-47 T 12-10-2018 IPR020355 Uncharacterised protein family YhcU HW35_08090 d8b47fa5b6b47b46d2a7594b20e206aa 218 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 8 198 2.2E-59 T 12-10-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein HW35_17165 df6d43272e653b00864c1414f20f72e3 422 Gene3D G3DSA:3.90.1150.60 17 411 4.2E-185 T 12-10-2018 HW35_17165 df6d43272e653b00864c1414f20f72e3 422 Gene3D G3DSA:3.40.640.10 58 271 4.2E-185 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HW35_17165 df6d43272e653b00864c1414f20f72e3 422 SUPERFAMILY SSF53383 60 398 1.02E-44 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HW35_17165 df6d43272e653b00864c1414f20f72e3 422 Pfam PF06838 Methionine gamma-lyase 14 414 4.1E-213 T 12-10-2018 IPR009651 Putative methionine gamma-lyase HW35_03235 dded37319d057fe1a1b329af7642e1db 375 Gene3D G3DSA:3.40.50.2000 176 357 6.3E-122 T 12-10-2018 HW35_03235 dded37319d057fe1a1b329af7642e1db 375 Pfam PF00534 Glycosyl transferases group 1 189 351 1.0E-41 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 HW35_03235 dded37319d057fe1a1b329af7642e1db 375 Gene3D G3DSA:3.40.50.2000 23 370 6.3E-122 T 12-10-2018 HW35_03235 dded37319d057fe1a1b329af7642e1db 375 Pfam PF13439 Glycosyltransferase Family 4 14 178 1.1E-24 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 HW35_03235 dded37319d057fe1a1b329af7642e1db 375 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 4 374 1.8E-178 T 12-10-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 HW35_03235 dded37319d057fe1a1b329af7642e1db 375 SUPERFAMILY SSF53756 9 374 3.21E-88 T 12-10-2018 HW35_01570 7258e3ca62a216b986b321780067a1f9 195 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 95 184 8.8E-7 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal HW35_01570 7258e3ca62a216b986b321780067a1f9 195 SUPERFAMILY SSF46689 5 72 2.99E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_01570 7258e3ca62a216b986b321780067a1f9 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 2.5E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_01570 7258e3ca62a216b986b321780067a1f9 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_01570 7258e3ca62a216b986b321780067a1f9 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_01570 7258e3ca62a216b986b321780067a1f9 195 SUPERFAMILY SSF48498 89 185 5.56E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily HW35_01570 7258e3ca62a216b986b321780067a1f9 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HW35_01570 7258e3ca62a216b986b321780067a1f9 195 Gene3D G3DSA:1.10.357.10 7 187 4.8E-26 T 12-10-2018 HW35_15310 4d682197560aae12f8b836089af2e2d5 310 Gene3D G3DSA:1.10.3720.10 84 298 7.8E-19 T 12-10-2018 IPR035906 MetI-like superfamily HW35_15310 4d682197560aae12f8b836089af2e2d5 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 5.4E-40 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_15310 4d682197560aae12f8b836089af2e2d5 310 SUPERFAMILY SSF161098 91 291 1.2E-15 T 12-10-2018 IPR035906 MetI-like superfamily HW35_13845 3fa482f9f44c12f9d3cb09e418b93f35 204 Gene3D G3DSA:1.20.144.10 5 184 7.0E-20 T 12-10-2018 HW35_13845 3fa482f9f44c12f9d3cb09e418b93f35 204 Pfam PF01569 PAP2 superfamily 90 171 1.5E-17 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HW35_13845 3fa482f9f44c12f9d3cb09e418b93f35 204 SUPERFAMILY SSF48317 6 172 1.83E-34 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily HW35_13845 3fa482f9f44c12f9d3cb09e418b93f35 204 SMART SM00014 58 166 8.3E-19 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HW35_07720 c5bcf7df8cfc1b2f3fd4396177300a6a 82 Pfam PF09964 Uncharacterized protein conserved in bacteria (DUF2198) 8 72 1.6E-30 T 12-10-2018 IPR019242 Protein of unknown function DUF2198 HW35_07445 9554a24e32d23d5251aeb0c5fdbd1ed9 322 Gene3D G3DSA:3.90.25.30 168 307 1.0E-135 T 12-10-2018 HW35_07445 9554a24e32d23d5251aeb0c5fdbd1ed9 322 Gene3D G3DSA:3.40.50.720 6 303 1.0E-135 T 12-10-2018 HW35_07445 9554a24e32d23d5251aeb0c5fdbd1ed9 322 Pfam PF02719 Polysaccharide biosynthesis protein 9 279 1.6E-105 T 12-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain HW35_07445 9554a24e32d23d5251aeb0c5fdbd1ed9 322 SUPERFAMILY SSF51735 6 270 3.9E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_07445 9554a24e32d23d5251aeb0c5fdbd1ed9 322 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 4 319 2.0E-164 T 12-10-2018 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00520+4.2.1.115|MetaCyc: PWY-6143|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 HW35_00055 3a96119c5e59373d02d6f902884c7604 155 Gene3D G3DSA:3.20.80.10 1 154 6.7E-23 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily HW35_00055 3a96119c5e59373d02d6f902884c7604 155 SUPERFAMILY SSF55136 2 152 2.44E-18 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily HW35_00055 3a96119c5e59373d02d6f902884c7604 155 Pfam PF06445 GyrI-like small molecule binding domain 3 152 5.2E-20 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain HW35_00055 3a96119c5e59373d02d6f902884c7604 155 SMART SM00871 1 152 1.2E-15 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding HW35_13415 117c9f3c59e0063d334c9d348f1d4146 253 Pfam PF06738 Putative threonine/serine exporter 13 252 8.2E-79 T 12-10-2018 IPR010619 Putative threonine/serine exporter HW35_05040 df5ce342e9a08d99790cfa3f5f65f2d2 97 TIGRFAM TIGR00062 L27: ribosomal protein bL27 10 91 3.1E-40 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05040 df5ce342e9a08d99790cfa3f5f65f2d2 97 ProSitePatterns PS00831 Ribosomal protein L27 signature. 43 57 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HW35_05040 df5ce342e9a08d99790cfa3f5f65f2d2 97 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 37 78 1.0E-16 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05040 df5ce342e9a08d99790cfa3f5f65f2d2 97 SUPERFAMILY SSF110324 11 92 8.11E-32 T 12-10-2018 HW35_05040 df5ce342e9a08d99790cfa3f5f65f2d2 97 Gene3D G3DSA:2.40.50.100 29 94 7.7E-26 T 12-10-2018 HW35_05040 df5ce342e9a08d99790cfa3f5f65f2d2 97 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 10 93 27.04 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05040 df5ce342e9a08d99790cfa3f5f65f2d2 97 PRINTS PR00063 Ribosomal protein L27 signature 13 37 1.9E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05040 df5ce342e9a08d99790cfa3f5f65f2d2 97 PRINTS PR00063 Ribosomal protein L27 signature 63 87 1.9E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05040 df5ce342e9a08d99790cfa3f5f65f2d2 97 PRINTS PR00063 Ribosomal protein L27 signature 38 62 1.9E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_05040 df5ce342e9a08d99790cfa3f5f65f2d2 97 Pfam PF01016 Ribosomal L27 protein 11 90 8.5E-34 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HW35_03585 7b736354f11b81fd279d5c6bcee2a3d3 178 Pfam PF07670 Nucleoside recognition 47 146 7.1E-7 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HW35_15875 35352547530c35383a49a304ca36d18a 78 Pfam PF08796 Protein of unknown function (DUF1797) 7 77 2.7E-27 T 12-10-2018 IPR014904 Protein of unknown function DUF1797 HW35_15875 35352547530c35383a49a304ca36d18a 78 SUPERFAMILY SSF143567 2 78 1.57E-27 T 12-10-2018 IPR038073 YkuJ-like superfamily HW35_15875 35352547530c35383a49a304ca36d18a 78 Gene3D G3DSA:3.30.720.20 1 78 3.3E-32 T 12-10-2018 IPR038073 YkuJ-like superfamily HW35_15875 35352547530c35383a49a304ca36d18a 78 PIRSF PIRSF037356 1 78 1.7E-31 T 12-10-2018 IPR014904 Protein of unknown function DUF1797 HW35_06225 1f42bdf8c8632fa80f4e7c730693ffb4 554 Pfam PF03888 MucB/RseB N-terminal domain 109 278 7.2E-10 T 12-10-2018 IPR033434 MucB/RseB, N-terminal HW35_06225 1f42bdf8c8632fa80f4e7c730693ffb4 554 SUPERFAMILY SSF89392 107 294 9.61E-13 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX HW35_06225 1f42bdf8c8632fa80f4e7c730693ffb4 554 Gene3D G3DSA:2.50.20.10 102 286 1.0E-27 T 12-10-2018 HW35_15080 71116621ab763113f12b7286e567c763 130 Pfam PF10970 Spore germination protein GerPE 5 123 2.1E-37 T 12-10-2018 IPR024496 Spore germination protein GerPE HW35_15080 71116621ab763113f12b7286e567c763 130 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 6 124 1.0E-11 T 12-10-2018 IPR024496 Spore germination protein GerPE HW35_09450 8493787fb037c8d6d7fdc602b9946091 115 Gene3D G3DSA:2.70.180.10 1 115 1.4E-50 T 12-10-2018 IPR036492 Hypothetical protein YojF superfamily HW35_09450 8493787fb037c8d6d7fdc602b9946091 115 SUPERFAMILY SSF89442 1 115 3.4E-54 T 12-10-2018 IPR036492 Hypothetical protein YojF superfamily HW35_09450 8493787fb037c8d6d7fdc602b9946091 115 Pfam PF08830 Protein of unknown function (DUF1806) 4 114 1.7E-54 T 12-10-2018 IPR014934 Protein of unknown function DUF1806 HW35_03540 5af66d82afd5036801485ff6b353b7f9 394 ProDom PD136539 TRANSCRIPTION SIGMA-X NEGATIVE ACTIVITY RSIX REPRESSOR MEMBRANE EFFECTOR REGULATION REGULATOR 1 389 2.0E-18 T 12-10-2018 HW35_09180 12253b2fced5ee2bdd8fb4b146144768 344 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 40 165 2.5E-46 T 12-10-2018 IPR014202 Sporulation stage II, protein R HW35_09180 12253b2fced5ee2bdd8fb4b146144768 344 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 4 170 3.6E-61 T 12-10-2018 IPR014202 Sporulation stage II, protein R HW35_04035 497c5d4dbd45afd2f8445ac62637f50a 171 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 171 4.0E-67 T 12-10-2018 IPR014198 Stage III sporulation protein AB HW35_04035 497c5d4dbd45afd2f8445ac62637f50a 171 PIRSF PIRSF021435 1 171 6.9E-68 T 12-10-2018 IPR014198 Stage III sporulation protein AB HW35_04035 497c5d4dbd45afd2f8445ac62637f50a 171 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 171 2.9E-55 T 12-10-2018 IPR014198 Stage III sporulation protein AB HW35_11535 0fb90a7dcd75642cebe85a18d9b66caf 151 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 127 1.4E-38 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 HW35_11535 0fb90a7dcd75642cebe85a18d9b66caf 151 Gene3D G3DSA:3.40.50.300 1 150 3.0E-42 T 12-10-2018 HW35_11535 0fb90a7dcd75642cebe85a18d9b66caf 151 SUPERFAMILY SSF52540 25 139 2.15E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_11535 0fb90a7dcd75642cebe85a18d9b66caf 151 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 131 2.3E-41 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 HW35_09795 55103d221fe06c422d05e6f4db37ba9c 440 Pfam PF07435 YycH protein 4 434 4.6E-95 T 12-10-2018 IPR009996 Regulatory protein YycH HW35_09795 55103d221fe06c422d05e6f4db37ba9c 440 Gene3D G3DSA:3.30.310.160 221 359 2.3E-44 T 12-10-2018 HW35_01525 715eec1134dbd868c1fa8904dbd9255e 60 Pfam PF11867 Domain of unknown function (DUF3387) 4 55 2.2E-10 T 12-10-2018 IPR021810 Protein of unknown function DUF3387 HW35_00200 d241cd6fbf91c97a95362dcd467e6f96 260 Pfam PF01618 MotA/TolQ/ExbB proton channel family 103 214 3.5E-22 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel HW35_00200 d241cd6fbf91c97a95362dcd467e6f96 260 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 184 201 - T 12-10-2018 IPR000540 Flagellar motor protein MotA, conserved site HW35_05115 1b42dac024acb251601b4aa9b215cd88 165 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 30 1.2E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_05115 1b42dac024acb251601b4aa9b215cd88 165 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_05115 1b42dac024acb251601b4aa9b215cd88 165 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 5.1E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_15550 ffbf0d0165827454b6d4e792f23b5e82 397 Pfam PF02687 FtsX-like permease family 303 390 1.5E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HW35_15550 ffbf0d0165827454b6d4e792f23b5e82 397 Pfam PF12704 MacB-like periplasmic core domain 21 237 4.9E-33 T 12-10-2018 IPR025857 MacB-like periplasmic core domain HW35_12580 c5113cc0de86ec43e2396a04f8de0877 144 Pfam PF04657 Putative inner membrane exporter, YdcZ 5 140 5.2E-40 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ HW35_07250 faf2259e9126ae0f067477f1e27dde6b 473 Pfam PF13520 Amino acid permease 7 452 2.8E-51 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HW35_07250 faf2259e9126ae0f067477f1e27dde6b 473 Gene3D G3DSA:1.20.1740.10 3 472 1.4E-62 T 12-10-2018 HW35_07250 faf2259e9126ae0f067477f1e27dde6b 473 PIRSF PIRSF006060 4 473 3.9E-54 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HW35_01180 26a3e15af9376c196cee3368b236f684 273 Gene3D G3DSA:3.40.50.10090 14 259 1.4E-76 T 12-10-2018 HW35_01180 26a3e15af9376c196cee3368b236f684 273 SUPERFAMILY SSF69618 7 269 7.85E-52 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_01180 26a3e15af9376c196cee3368b236f684 273 Pfam PF02602 Uroporphyrinogen-III synthase HemD 20 260 6.8E-38 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HW35_01180 26a3e15af9376c196cee3368b236f684 273 Gene3D G3DSA:3.40.50.10090 38 174 1.4E-76 T 12-10-2018 HW35_12345 d85dc5a2770250b9ff8dc1405048a82d 404 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 79 1.2E-11 T 12-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HW35_12345 d85dc5a2770250b9ff8dc1405048a82d 404 Pfam PF01610 Transposase 150 390 1.0E-70 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HW35_00520 2071afc8d6cf742492e378fe81ad211a 257 Pfam PF01311 Bacterial export proteins, family 1 7 244 1.6E-66 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HW35_00520 2071afc8d6cf742492e378fe81ad211a 257 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 8 251 8.1E-58 T 12-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 HW35_00520 2071afc8d6cf742492e378fe81ad211a 257 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 74 93 6.8E-27 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HW35_00520 2071afc8d6cf742492e378fe81ad211a 257 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 177 199 6.8E-27 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HW35_00520 2071afc8d6cf742492e378fe81ad211a 257 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 15 36 6.8E-27 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HW35_00520 2071afc8d6cf742492e378fe81ad211a 257 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 199 218 6.8E-27 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HW35_12175 c64bc1180effbc61f9faadf35c8cb866 571 Pfam PF02652 L-lactate permease 10 558 6.9E-161 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HW35_12175 c64bc1180effbc61f9faadf35c8cb866 571 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 2 560 1.5E-157 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HW35_11070 c9b144b3229a48d412fe614f4f1dd04a 207 Pfam PF13490 Putative zinc-finger 2 36 1.4E-7 T 12-10-2018 IPR027383 Putative zinc-finger HW35_03510 96018118ff529f0e0d542e154235ca8f 203 Pfam PF02517 CAAX protease self-immunity 96 179 1.2E-9 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 HW35_12355 9486cb63fdc0d13f149de304c0e7bf59 468 Gene3D G3DSA:1.20.1730.10 20 467 1.7E-79 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily HW35_12355 9486cb63fdc0d13f149de304c0e7bf59 468 Pfam PF00474 Sodium:solute symporter family 33 414 3.4E-45 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 HW35_00985 76e59e9e6a25826dd0b335b4ac293a9b 43 Pfam PF13040 Fur-regulated basic protein B 2 38 7.2E-17 T 12-10-2018 IPR025004 Transcriptional regulatory protein SenN/SenS HW35_04350 f0080f1533518d24a761bb7d032bbb71 201 Gene3D G3DSA:3.40.50.1000 1 164 6.7E-11 T 12-10-2018 IPR023214 HAD superfamily HW35_04350 f0080f1533518d24a761bb7d032bbb71 201 PIRSF PIRSF021362 2 193 6.2E-68 T 12-10-2018 IPR009206 Nucleotidase, putative HW35_04350 f0080f1533518d24a761bb7d032bbb71 201 SUPERFAMILY SSF56784 3 163 6.88E-18 T 12-10-2018 IPR036412 HAD-like superfamily HW35_04350 f0080f1533518d24a761bb7d032bbb71 201 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 7 180 1.6E-6 T 12-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 HW35_07015 d18d59673d74b4c7e4ee9d4f0956c926 265 PIRSF PIRSF021383 1 252 2.0E-68 T 12-10-2018 IPR014197 Sporulation protein YunB HW35_07015 d18d59673d74b4c7e4ee9d4f0956c926 265 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 14 239 1.7E-53 T 12-10-2018 IPR014197 Sporulation protein YunB HW35_07015 d18d59673d74b4c7e4ee9d4f0956c926 265 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 148 236 8.8E-28 T 12-10-2018 IPR014197 Sporulation protein YunB HW35_10970 d7d4864508d648c95428cff4b9d733b0 350 SUPERFAMILY SSF52540 97 313 1.45E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_10970 d7d4864508d648c95428cff4b9d733b0 350 ProSitePatterns PS01215 Mrp family signature. 210 226 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 HW35_10970 d7d4864508d648c95428cff4b9d733b0 350 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 107 344 2.6E-84 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 HW35_10970 d7d4864508d648c95428cff4b9d733b0 350 SUPERFAMILY SSF117916 1 78 1.11E-5 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily HW35_10970 d7d4864508d648c95428cff4b9d733b0 350 Gene3D G3DSA:3.40.50.300 94 320 2.2E-66 T 12-10-2018 HW35_10970 d7d4864508d648c95428cff4b9d733b0 350 Hamap MF_02040 Iron-sulfur cluster carrier protein. 98 345 33.977 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein HW35_17560 e6a470d908171797e30e7187f370731e 274 Pfam PF04951 D-aminopeptidase 1 262 7.5E-96 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase HW35_17560 e6a470d908171797e30e7187f370731e 274 SUPERFAMILY SSF63992 1 274 4.71E-103 T 12-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily HW35_17560 e6a470d908171797e30e7187f370731e 274 PIRSF PIRSF015853 1 271 5.7E-108 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase HW35_17560 e6a470d908171797e30e7187f370731e 274 Gene3D G3DSA:3.30.1360.130 118 261 5.0E-102 T 12-10-2018 HW35_17560 e6a470d908171797e30e7187f370731e 274 Gene3D G3DSA:3.40.50.10780 1 213 5.0E-102 T 12-10-2018 IPR027476 D-aminopeptidase, N-terminal HW35_09495 fdb38293b5aa36967846c01108f88cff 225 SUPERFAMILY SSF52540 2 208 5.1E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_09495 fdb38293b5aa36967846c01108f88cff 225 Gene3D G3DSA:3.40.50.300 1 219 7.3E-60 T 12-10-2018 HW35_09495 fdb38293b5aa36967846c01108f88cff 225 Pfam PF00005 ABC transporter 17 159 5.7E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HW35_09495 fdb38293b5aa36967846c01108f88cff 225 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HW35_09495 fdb38293b5aa36967846c01108f88cff 225 SMART SM00382 26 204 1.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain HW35_15090 d58154d1db8b9c048e4a7248ff138957 204 Pfam PF10737 Spore germination protein GerPC 23 196 2.1E-48 T 12-10-2018 IPR019673 Spore germination protein GerPC HW35_14485 6dad1ee376e22d65c25fb6be77a5a3b2 71 Gene3D G3DSA:1.10.260.40 5 63 1.4E-7 T 12-10-2018 HW35_14485 6dad1ee376e22d65c25fb6be77a5a3b2 71 SUPERFAMILY SSF47413 4 61 3.5E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HW35_02495 8becb5e92511aa7fef84e8361857ca52 387 Gene3D G3DSA:3.40.710.10 16 295 5.4E-84 T 12-10-2018 HW35_02495 8becb5e92511aa7fef84e8361857ca52 387 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 27 254 7.1E-46 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HW35_02495 8becb5e92511aa7fef84e8361857ca52 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 107 124 2.2E-9 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_02495 8becb5e92511aa7fef84e8361857ca52 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 59 70 2.2E-9 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HW35_02495 8becb5e92511aa7fef84e8361857ca52 387 SUPERFAMILY SSF56601 2 274 2.54E-59 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HW35_09045 3a8cb3f867c13a9f55e0588ba2bebf8a 173 Gene3D G3DSA:1.20.120.1200 8 166 1.1E-40 T 12-10-2018 HW35_09045 3a8cb3f867c13a9f55e0588ba2bebf8a 173 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 21 162 3.1E-36 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_17095 2b4dd7271be6972c928128f5e529066c 203 Pfam PF03358 NADPH-dependent FMN reductase 6 147 1.7E-18 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HW35_17095 2b4dd7271be6972c928128f5e529066c 203 SUPERFAMILY SSF52218 5 196 3.69E-48 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_17095 2b4dd7271be6972c928128f5e529066c 203 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 176 1.9E-46 T 12-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 HW35_17095 2b4dd7271be6972c928128f5e529066c 203 Gene3D G3DSA:3.40.50.360 1 203 1.1E-67 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_05345 053e8b2234f7ed6326ce7268d7fb8d4e 173 Gene3D G3DSA:3.60.21.10 1 169 6.9E-45 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like HW35_05345 053e8b2234f7ed6326ce7268d7fb8d4e 173 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 149 5.1E-31 T 12-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 HW35_05345 053e8b2234f7ed6326ce7268d7fb8d4e 173 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 144 6.2E-30 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 HW35_05345 053e8b2234f7ed6326ce7268d7fb8d4e 173 SUPERFAMILY SSF56300 1 160 9.88E-43 T 12-10-2018 HW35_13015 d97f31e82f931a400318cb7231e8d8d1 184 Pfam PF03358 NADPH-dependent FMN reductase 1 145 3.7E-30 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HW35_13015 d97f31e82f931a400318cb7231e8d8d1 184 SUPERFAMILY SSF52218 1 174 2.79E-34 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_13015 d97f31e82f931a400318cb7231e8d8d1 184 Gene3D G3DSA:3.40.50.360 1 178 2.0E-41 T 12-10-2018 IPR029039 Flavoprotein-like superfamily HW35_01300 dd13933cd0c9b03ea92399ca0b041408 260 SUPERFAMILY SSF46565 201 255 5.89E-9 T 12-10-2018 IPR036869 Chaperone J-domain superfamily HW35_01300 dd13933cd0c9b03ea92399ca0b041408 260 Gene3D G3DSA:1.10.287.110 195 258 6.8E-8 T 12-10-2018 IPR036869 Chaperone J-domain superfamily HW35_13075 092fa0a5c5a1636c2a20b73205d43d2a 408 Pfam PF00999 Sodium/hydrogen exchanger family 12 376 1.5E-59 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 HW35_13075 092fa0a5c5a1636c2a20b73205d43d2a 408 Gene3D G3DSA:1.20.1530.20 2 386 1.4E-68 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily HW35_15855 7019d7e0b6c88940d660cfc2a3254960 157 Pfam PF08388 Group II intron, maturase-specific domain 25 97 5.4E-21 T 12-10-2018 IPR013597 Group II intron, maturase-specific HW35_13195 4e7602f8a6717e55d2ddbdb398b56534 139 SUPERFAMILY SSF55961 3 138 2.96E-42 T 12-10-2018 HW35_13195 4e7602f8a6717e55d2ddbdb398b56534 139 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 16 138 3.2E-15 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like HW35_13195 4e7602f8a6717e55d2ddbdb398b56534 139 Gene3D G3DSA:3.30.530.20 1 139 9.8E-43 T 12-10-2018 IPR023393 START-like domain superfamily HW35_05430 ebc32616a4013a11fecf40c04edbec83 147 SUPERFAMILY SSF111126 18 129 5.23E-23 T 12-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily HW35_05430 ebc32616a4013a11fecf40c04edbec83 147 Pfam PF10702 Protein of unknown function (DUF2507) 22 143 2.7E-48 T 12-10-2018 IPR019642 Protein of unknown function DUF2507 HW35_05430 ebc32616a4013a11fecf40c04edbec83 147 Gene3D G3DSA:3.30.1380.20 1 147 1.8E-54 T 12-10-2018 HW35_12215 426ac162045773f123a53032cf1aac3c 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 249 3.6E-64 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 HW35_12215 426ac162045773f123a53032cf1aac3c 264 Gene3D G3DSA:3.60.110.10 1 264 1.9E-87 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily HW35_12215 426ac162045773f123a53032cf1aac3c 264 SUPERFAMILY SSF56317 1 263 9.03E-81 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily HW35_14790 39758ae0c83146985a867002c1a4b323 68 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HW35_14790 39758ae0c83146985a867002c1a4b323 68 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HW35_14790 39758ae0c83146985a867002c1a4b323 68 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 1.4E-23 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 HW35_14790 39758ae0c83146985a867002c1a4b323 68 Gene3D G3DSA:1.10.8.910 8 68 1.3E-31 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily HW35_02225 7c73d9337a68f4b689bffa772cb182b5 118 Gene3D G3DSA:3.40.50.2300 17 91 1.2E-6 T 12-10-2018 HW35_09065 91929a5a730d1e1d0c695e54203065d2 470 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 401 456 1.0E-15 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09065 91929a5a730d1e1d0c695e54203065d2 470 SUPERFAMILY SSF143243 337 467 6.02E-41 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09065 91929a5a730d1e1d0c695e54203065d2 470 Gene3D G3DSA:3.30.460.80 300 447 4.1E-33 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09065 91929a5a730d1e1d0c695e54203065d2 470 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 349 464 1.3E-37 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_04755 31a924b9d89fdcd096c9f5f25bf2ea24 375 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 26 375 34.073 T 12-10-2018 IPR003770 Endolytic murein transglycosylase HW35_04755 31a924b9d89fdcd096c9f5f25bf2ea24 375 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 25 374 5.1E-109 T 12-10-2018 IPR003770 Endolytic murein transglycosylase HW35_04755 31a924b9d89fdcd096c9f5f25bf2ea24 375 Pfam PF02618 YceG-like family 66 368 3.3E-81 T 12-10-2018 IPR003770 Endolytic murein transglycosylase HW35_04755 31a924b9d89fdcd096c9f5f25bf2ea24 375 Gene3D G3DSA:1.10.8.1150 60 135 5.0E-27 T 12-10-2018 HW35_11365 b1eecb11f0143521068e247505c0f7a4 197 Pfam PF09335 SNARE associated Golgi protein 29 155 2.3E-25 T 12-10-2018 IPR032816 SNARE associated Golgi protein HW35_02680 dd254ec59c28af7ed4c2dd946ecb1de9 102 ProDom PD030115 YODL GK1575 5 101 6.0E-22 T 12-10-2018 HW35_02680 dd254ec59c28af7ed4c2dd946ecb1de9 102 Pfam PF14191 YodL-like 27 86 4.1E-8 T 12-10-2018 IPR025923 YodL-like HW35_01160 82e7a26575978abbb6fdf19f32efa38d 491 Gene3D G3DSA:1.10.4160.10 1 466 2.6E-107 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily HW35_01160 82e7a26575978abbb6fdf19f32efa38d 491 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 13 438 1.6E-56 T 12-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 HW35_01565 f46c06739c08c4c3f7971d03816dd4b5 247 Pfam PF09524 Conserved phage C-terminus (Phg_2220_C) 158 230 9.2E-30 T 12-10-2018 IPR011741 Phage conserved hypothetical protein, C-terminal HW35_01565 f46c06739c08c4c3f7971d03816dd4b5 247 TIGRFAM TIGR02220 phg_TIGR02220: phage conserved hypothetical protein, C-terminal domain 156 231 6.0E-31 T 12-10-2018 IPR011741 Phage conserved hypothetical protein, C-terminal HW35_09565 9ba6cbb43ecc309b6f012ee8506cbeb7 115 Pfam PF04266 ASCH domain 26 112 1.8E-4 T 12-10-2018 IPR007374 ASCH domain HW35_09565 9ba6cbb43ecc309b6f012ee8506cbeb7 115 SUPERFAMILY SSF88697 19 111 1.12E-12 T 12-10-2018 IPR015947 PUA-like superfamily HW35_09565 9ba6cbb43ecc309b6f012ee8506cbeb7 115 SMART SM01022 18 113 9.8E-5 T 12-10-2018 IPR007374 ASCH domain HW35_13230 dc780d47d7e3d77473112e455dd1af9c 156 SUPERFAMILY SSF55804 3 152 9.16E-37 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_13230 dc780d47d7e3d77473112e455dd1af9c 156 Gene3D G3DSA:3.40.930.10 4 156 7.0E-46 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 HW35_13230 dc780d47d7e3d77473112e455dd1af9c 156 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 151 5.5E-35 T 12-10-2018 IPR002178 PTS EIIA type-2 domain HW35_06410 c791b88a6d9f46bc0aa6ca02b533a601 798 Pfam PF00343 Carbohydrate phosphorylase 93 794 0.0 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 HW35_06410 c791b88a6d9f46bc0aa6ca02b533a601 798 PIRSF PIRSF000460 3 798 3.9E-235 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 HW35_06410 c791b88a6d9f46bc0aa6ca02b533a601 798 Gene3D G3DSA:3.40.50.2000 16 794 0.0 T 12-10-2018 HW35_06410 c791b88a6d9f46bc0aa6ca02b533a601 798 SUPERFAMILY SSF53756 4 797 0.0 T 12-10-2018 HW35_06410 c791b88a6d9f46bc0aa6ca02b533a601 798 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 5 794 0.0 T 12-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 HW35_06410 c791b88a6d9f46bc0aa6ca02b533a601 798 Gene3D G3DSA:3.40.50.2000 458 785 0.0 T 12-10-2018 HW35_01530 f62d1c712692849d899700a42682ca1d 615 Pfam PF14281 PD-(D/E)XK nuclease superfamily 27 227 2.3E-31 T 12-10-2018 IPR029470 PD-(D/E)XK nuclease superfamily 4 HW35_12740 df5648c911cd2380952552515b242352 401 Gene3D G3DSA:3.60.120.10 3 401 1.4E-132 T 12-10-2018 IPR005801 ADC synthase GO:0009058 HW35_12740 df5648c911cd2380952552515b242352 401 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 112 395 4.8E-88 T 12-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 HW35_12740 df5648c911cd2380952552515b242352 401 SUPERFAMILY SSF56322 27 397 5.49E-93 T 12-10-2018 IPR005801 ADC synthase GO:0009058 HW35_12740 df5648c911cd2380952552515b242352 401 Pfam PF00425 chorismate binding enzyme 124 388 4.2E-78 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal HW35_17495 949a4acbe19e6cdca24c0559efa8a09d 199 Pfam PF01583 Adenylylsulphate kinase 27 179 5.5E-74 T 12-10-2018 HW35_17495 949a4acbe19e6cdca24c0559efa8a09d 199 SUPERFAMILY SSF52540 25 197 5.32E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_17495 949a4acbe19e6cdca24c0559efa8a09d 199 Gene3D G3DSA:3.40.50.300 3 199 8.7E-86 T 12-10-2018 HW35_17495 949a4acbe19e6cdca24c0559efa8a09d 199 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 9 193 3.4E-87 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HW35_17495 949a4acbe19e6cdca24c0559efa8a09d 199 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 25 197 39.7 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HW35_00920 9ffb4b897823a7703d376473650be2c6 320 Gene3D G3DSA:3.40.50.720 1 311 2.7E-103 T 12-10-2018 HW35_00920 9ffb4b897823a7703d376473650be2c6 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 240 3.8E-22 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HW35_00920 9ffb4b897823a7703d376473650be2c6 320 SUPERFAMILY SSF51735 1 315 1.02E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_03755 ab938a5f193c8090de52f2520ecbccb6 303 Pfam PF00248 Aldo/keto reductase family 15 293 1.2E-61 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain HW35_03755 ab938a5f193c8090de52f2520ecbccb6 303 SUPERFAMILY SSF51430 1 294 9.56E-78 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily HW35_03755 ab938a5f193c8090de52f2520ecbccb6 303 Gene3D G3DSA:3.20.20.100 1 295 3.9E-103 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily HW35_03755 ab938a5f193c8090de52f2520ecbccb6 303 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.4E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_03755 ab938a5f193c8090de52f2520ecbccb6 303 PRINTS PR00069 Aldo-keto reductase signature 103 121 1.4E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_03755 ab938a5f193c8090de52f2520ecbccb6 303 PRINTS PR00069 Aldo-keto reductase signature 134 151 1.4E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HW35_17500 f39920d6b0f7128e8aae5845ca327dfb 240 SUPERFAMILY SSF53800 1 238 5.67E-44 T 12-10-2018 HW35_17500 f39920d6b0f7128e8aae5845ca327dfb 240 Gene3D G3DSA:3.40.50.1400 125 240 1.2E-15 T 12-10-2018 HW35_17500 f39920d6b0f7128e8aae5845ca327dfb 240 Gene3D G3DSA:3.40.50.1400 1 121 7.1E-27 T 12-10-2018 HW35_17500 f39920d6b0f7128e8aae5845ca327dfb 240 Pfam PF01903 CbiX 9 110 7.6E-28 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 HW35_17500 f39920d6b0f7128e8aae5845ca327dfb 240 Pfam PF01903 CbiX 134 235 3.9E-15 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 HW35_04260 4fb20b00a1e83fdb47bbc2d8123a72fd 259 Pfam PF01940 Integral membrane protein DUF92 10 249 2.6E-61 T 12-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 HW35_16945 463ab7be3bebe0e9a5a241af95551ef6 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 296 4.1E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 HW35_13705 8c66d791f021cebe52c9ebdb78d13ce4 278 PIRSF PIRSF035875 2 277 1.8E-84 T 12-10-2018 IPR017039 Virulence factor BrkB HW35_13705 8c66d791f021cebe52c9ebdb78d13ce4 278 Pfam PF03631 Virulence factor BrkB 21 273 1.3E-71 T 12-10-2018 IPR017039 Virulence factor BrkB HW35_13705 8c66d791f021cebe52c9ebdb78d13ce4 278 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 13 269 1.9E-59 T 12-10-2018 IPR017039 Virulence factor BrkB HW35_00145 a90cdb90e9599bea70d30519b5d0952f 240 Pfam PF00586 AIR synthase related protein, N-terminal domain 32 110 1.1E-4 T 12-10-2018 IPR016188 PurM-like, N-terminal domain HW35_07705 cf55e0c8d41b7dbed121fcccc31b20e0 368 Pfam PF13349 Putative adhesin 162 364 3.5E-14 T 12-10-2018 IPR025164 Putative adhesin HW35_07705 cf55e0c8d41b7dbed121fcccc31b20e0 368 PIRSF PIRSF012569 1 367 6.3E-101 T 12-10-2018 IPR016599 Uncharacterised conserved protein UCP012569 HW35_11570 ff5252ae23f9beeed9ad2d2a9973db09 66 Pfam PF14146 Domain of unknown function (DUF4305) 18 54 3.8E-16 T 12-10-2018 IPR025426 Protein of unknown function DUF4305 HW35_11570 ff5252ae23f9beeed9ad2d2a9973db09 66 ProDom PD053380 YDIK LIPOPROTEIN TRANSMEMBRANE MEMBRANE PRECURSOR PALMITATE SIGNAL 3 65 4.0E-6 T 12-10-2018 HW35_02865 f22bf210270f6549bf2d4516ca0a18d8 203 Pfam PF02342 TerD domain 1 202 3.0E-78 T 12-10-2018 IPR003325 TerD domain HW35_02865 f22bf210270f6549bf2d4516ca0a18d8 203 Gene3D G3DSA:2.60.60.30 19 201 5.9E-64 T 12-10-2018 HW35_10105 28d56cf93d8b1af05d8d8526021e012f 71 Pfam PF10704 Protein of unknown function (DUF2508) 1 69 1.8E-23 T 12-10-2018 IPR019644 Protein of unknown function DUF2508 HW35_04235 53a7ceca7cd6281ee56d487ad9903dd6 58 Pfam PF10958 Protein of unknown function (DUF2759) 6 55 2.9E-22 T 12-10-2018 IPR024490 Protein of unknown function DUF2759 HW35_04235 53a7ceca7cd6281ee56d487ad9903dd6 58 ProDom PD052097 RELATED ALKALIPHILY YQGW MEMBRANE TRANSMEMBRANE SPANNING 1 55 6.0E-12 T 12-10-2018 IPR024490 Protein of unknown function DUF2759 HW35_17405 a7a55dfd0811d8cf9771fdba8b5846d2 254 Pfam PF01925 Sulfite exporter TauE/SafE 6 253 1.3E-47 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HW35_06755 4cec1de25bdae5c4997fee3046872ce5 454 PIRSF PIRSF006060 2 452 5.2E-46 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HW35_06755 4cec1de25bdae5c4997fee3046872ce5 454 Gene3D G3DSA:1.20.1740.10 7 450 1.8E-48 T 12-10-2018 HW35_06755 4cec1de25bdae5c4997fee3046872ce5 454 Pfam PF00324 Amino acid permease 20 398 8.1E-53 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 HW35_15030 d3526f93ec480f324c9303d4446b3b9f 78 Gene3D G3DSA:4.10.810.10 17 77 1.6E-9 T 12-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 HW35_15030 d3526f93ec480f324c9303d4446b3b9f 78 Pfam PF08858 IDEAL domain 34 69 1.4E-7 T 12-10-2018 IPR014957 IDEAL domain HW35_13255 9d0fec281883fa3efc7bf85f5a66c6a1 104 Pfam PF13031 Protein of unknown function (DUF3892) 36 102 1.0E-16 T 12-10-2018 IPR024997 Protein of unknown function DUF3892 HW35_02120 522bf22788f53b39a7a25cf5a0c29316 373 Pfam PF10720 Protein of unknown function (DUF2515) 41 363 1.0E-126 T 12-10-2018 IPR019658 Protein of unknown function DUF2515 HW35_09470 4b256350429d8cf092cd40308ed8b11e 147 Gene3D G3DSA:1.10.760.10 3 147 7.3E-12 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HW35_09470 4b256350429d8cf092cd40308ed8b11e 147 SUPERFAMILY SSF46626 71 145 7.25E-9 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HW35_09410 edbebc1810780086d9d6ec4819f51580 123 Pfam PF04241 Protein of unknown function (DUF423) 18 105 8.1E-33 T 12-10-2018 IPR006696 Protein of unknown function DUF423 HW35_11415 9a95eac7b6cd398ca13cf573556bba91 338 Gene3D G3DSA:2.50.20.10 23 214 1.3E-11 T 12-10-2018 HW35_11415 9a95eac7b6cd398ca13cf573556bba91 338 Pfam PF14285 Domain of unknown function (DUF4367) 251 332 6.1E-5 T 12-10-2018 IPR025377 Domain of unknown function DUF4367 HW35_11415 9a95eac7b6cd398ca13cf573556bba91 338 SUPERFAMILY SSF89392 28 204 2.0E-17 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX HW35_16350 8640731466a5633b654d17819d83d0d4 243 Gene3D G3DSA:3.30.70.1880 84 242 1.8E-16 T 12-10-2018 HW35_16350 8640731466a5633b654d17819d83d0d4 243 Pfam PF05949 Bacterial protein of unknown function (DUF881) 86 235 9.6E-28 T 12-10-2018 IPR010273 Protein of unknown function DUF881 HW35_13220 d9713d6c8f80039841ebdc844bfd98f1 126 Pfam PF04343 Protein of unknown function, DUF488 6 114 7.7E-32 T 12-10-2018 IPR007438 Protein of unknown function DUF488 HW35_08730 6b42bdd935beeaac54a8042582cffbf3 336 SMART SM01126 145 304 5.2E-37 T 12-10-2018 IPR024445 ISXO2-like transposase domain HW35_08730 6b42bdd935beeaac54a8042582cffbf3 336 Pfam PF12762 ISXO2-like transposase domain 145 301 2.0E-20 T 12-10-2018 IPR024445 ISXO2-like transposase domain HW35_09335 7a454794ae71895007b27cbf4e412c0c 169 Pfam PF08741 YwhD family 5 166 8.5E-88 T 12-10-2018 IPR014852 Uncharacterised protein YwhD HW35_12910 20409d533008c3d3ecee24f8f8a94517 142 SUPERFAMILY SSF159888 11 130 1.44E-8 T 12-10-2018 HW35_12910 20409d533008c3d3ecee24f8f8a94517 142 Pfam PF08818 Domain of unknown function (DU1801) 25 129 9.3E-16 T 12-10-2018 IPR014922 Domain of unknown function DUF1801 HW35_10310 97e6611015ebdfad49bb9781e0851d95 100 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 16 100 4.0E-36 T 12-10-2018 IPR012504 Sporulation protein YabP HW35_10310 97e6611015ebdfad49bb9781e0851d95 100 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 17 100 3.2E-34 T 12-10-2018 IPR012504 Sporulation protein YabP HW35_10310 97e6611015ebdfad49bb9781e0851d95 100 Gene3D G3DSA:2.60.40.2000 25 82 1.8E-24 T 12-10-2018 IPR038705 YabP superfamily HW35_10310 97e6611015ebdfad49bb9781e0851d95 100 PIRSF PIRSF011576 1 100 6.4E-52 T 12-10-2018 IPR012504 Sporulation protein YabP HW35_10310 97e6611015ebdfad49bb9781e0851d95 100 Pfam PF07873 YabP family 17 82 7.6E-21 T 12-10-2018 IPR022476 Sporulation protein YabP/YqfC HW35_15125 3544c1bec5319f6c30b9ccfa2ee2e6a1 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.612 T 12-10-2018 IPR007551 Protein of unknown function DUF520 HW35_15125 3544c1bec5319f6c30b9ccfa2ee2e6a1 163 SUPERFAMILY SSF89963 92 163 6.8E-26 T 12-10-2018 IPR036183 YajQ-like superfamily HW35_15125 3544c1bec5319f6c30b9ccfa2ee2e6a1 163 Gene3D G3DSA:3.30.70.860 6 163 1.2E-62 T 12-10-2018 IPR035571 UPF0234-like, C-terminal HW35_15125 3544c1bec5319f6c30b9ccfa2ee2e6a1 163 SUPERFAMILY SSF89963 6 90 3.27E-30 T 12-10-2018 IPR036183 YajQ-like superfamily HW35_15125 3544c1bec5319f6c30b9ccfa2ee2e6a1 163 Gene3D G3DSA:3.30.70.990 12 101 1.2E-62 T 12-10-2018 IPR035570 UPF0234, N-terminal HW35_15125 3544c1bec5319f6c30b9ccfa2ee2e6a1 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 2.7E-63 T 12-10-2018 IPR007551 Protein of unknown function DUF520 HW35_09165 aa6fbbf5bcb0320108082ffdccf57b22 185 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 6 183 20.103 T 12-10-2018 IPR022929 Putative manganese efflux pump MntP HW35_09165 aa6fbbf5bcb0320108082ffdccf57b22 185 Pfam PF02659 Putative manganese efflux pump 34 181 4.3E-39 T 12-10-2018 IPR003810 Putative manganese efflux pump HW35_02140 f5a501784ce90ae49de798cc2ca7c9ca 176 Pfam PF12840 Helix-turn-helix domain 7 61 7.8E-12 T 12-10-2018 HW35_02140 f5a501784ce90ae49de798cc2ca7c9ca 176 Gene3D G3DSA:1.10.10.10 1 77 9.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_02140 f5a501784ce90ae49de798cc2ca7c9ca 176 SUPERFAMILY SSF46785 8 151 2.14E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_02140 f5a501784ce90ae49de798cc2ca7c9ca 176 Gene3D G3DSA:1.20.1270.400 85 174 5.9E-31 T 12-10-2018 HW35_01365 c9078ccb4418bd84dd72a2bad837652e 62 Pfam PF13076 Fur-regulated basic protein A 12 47 1.7E-15 T 12-10-2018 IPR025072 Fur-regulated basic protein A HW35_13265 52831360bcc862c0ed2f8160fe43c5b5 122 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 72 109 2.0E-6 T 12-10-2018 HW35_13265 52831360bcc862c0ed2f8160fe43c5b5 122 Pfam PF14184 Regulatory protein YrvL 2 115 2.0E-22 T 12-10-2018 IPR025912 Regulatory protein YrvL HW35_12315 6f14044defc61ff1ca1a8c0df8694ebe 429 Pfam PF00860 Permease family 17 387 6.7E-33 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 HW35_11580 62d95ee8c9f1ed7c9b9ba54041fe0538 94 SMART SM00883 1 93 1.2E-56 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HW35_11580 62d95ee8c9f1ed7c9b9ba54041fe0538 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 9.1E-37 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HW35_11580 62d95ee8c9f1ed7c9b9ba54041fe0538 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 HW35_11580 62d95ee8c9f1ed7c9b9ba54041fe0538 94 PRINTS PR00297 10kDa chaperonin signature 2 17 1.1E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HW35_11580 62d95ee8c9f1ed7c9b9ba54041fe0538 94 PRINTS PR00297 10kDa chaperonin signature 24 45 1.1E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HW35_11580 62d95ee8c9f1ed7c9b9ba54041fe0538 94 PRINTS PR00297 10kDa chaperonin signature 59 71 1.1E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HW35_11580 62d95ee8c9f1ed7c9b9ba54041fe0538 94 PRINTS PR00297 10kDa chaperonin signature 80 93 1.1E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HW35_11580 62d95ee8c9f1ed7c9b9ba54041fe0538 94 SUPERFAMILY SSF50129 2 94 1.51E-35 T 12-10-2018 IPR011032 GroES-like superfamily HW35_11580 62d95ee8c9f1ed7c9b9ba54041fe0538 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 27.675 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HW35_11580 62d95ee8c9f1ed7c9b9ba54041fe0538 94 Gene3D G3DSA:2.30.33.40 1 94 1.6E-38 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 HW35_15720 1834035282dbf41896a6c734566f6e91 200 Pfam PF01553 Acyltransferase 19 142 1.5E-23 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 HW35_15720 1834035282dbf41896a6c734566f6e91 200 SUPERFAMILY SSF69593 15 197 1.83E-39 T 12-10-2018 HW35_15720 1834035282dbf41896a6c734566f6e91 200 SMART SM00563 33 144 8.8E-29 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 HW35_13205 9b5d73aae25d45b0a007683f6c49f157 311 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 305 4.3E-96 T 12-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 HW35_13205 9b5d73aae25d45b0a007683f6c49f157 311 Gene3D G3DSA:3.20.20.140 1 306 2.4E-110 T 12-10-2018 HW35_13205 9b5d73aae25d45b0a007683f6c49f157 311 SUPERFAMILY SSF51556 1 306 2.65E-73 T 12-10-2018 IPR032466 Metal-dependent hydrolase HW35_00100 12341faad6c531d6b6c707ec737662c7 327 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 7 304 6.7E-84 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 HW35_00100 12341faad6c531d6b6c707ec737662c7 327 Pfam PF03186 CobD/Cbib protein 10 294 7.5E-104 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 HW35_00100 12341faad6c531d6b6c707ec737662c7 327 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 324 95.979 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 HW35_15495 0a8190be9564e249b3cf896e286cfa29 75 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 12-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 HW35_15495 0a8190be9564e249b3cf896e286cfa29 75 SMART SM00857 3 75 0.0088 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HW35_15495 0a8190be9564e249b3cf896e286cfa29 75 Gene3D G3DSA:3.40.50.1390 2 75 1.2E-21 T 12-10-2018 HW35_15495 0a8190be9564e249b3cf896e286cfa29 75 Pfam PF00239 Resolvase, N terminal domain 5 75 1.2E-15 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HW35_15495 0a8190be9564e249b3cf896e286cfa29 75 SUPERFAMILY SSF53041 3 75 1.31E-14 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 HW35_17215 757c8661549a9ce422e086a4e7801fcc 69 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 23 59 6.0E-14 T 12-10-2018 IPR005359 Protein with unknown function UPF0154 HW35_17215 757c8661549a9ce422e086a4e7801fcc 69 Hamap MF_00363 UPF0154 protein . 1 69 20.079 T 12-10-2018 IPR005359 Protein with unknown function UPF0154 HW35_17215 757c8661549a9ce422e086a4e7801fcc 69 Pfam PF03672 Uncharacterised protein family (UPF0154) 8 66 2.8E-31 T 12-10-2018 IPR005359 Protein with unknown function UPF0154 HW35_12440 42c0eb0c9625a3aaac0b9c634757605e 67 SUPERFAMILY SSF54285 2 66 7.56E-18 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp HW35_12440 42c0eb0c9625a3aaac0b9c634757605e 67 Gene3D G3DSA:3.10.20.30 3 67 2.2E-20 T 12-10-2018 IPR012675 Beta-grasp domain superfamily HW35_12440 42c0eb0c9625a3aaac0b9c634757605e 67 Pfam PF02597 ThiS family 6 67 7.3E-13 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 HW35_12440 42c0eb0c9625a3aaac0b9c634757605e 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 67 1.0E-19 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis HW35_11290 1e40739ce9946b8a91a23b72f99aacea 494 PIRSF PIRSF026631 1 492 1.3E-98 T 12-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 HW35_11290 1e40739ce9946b8a91a23b72f99aacea 494 Pfam PF03703 Bacterial PH domain 63 142 1.4E-14 T 12-10-2018 IPR005182 Domain of unknown function DUF304 HW35_11290 1e40739ce9946b8a91a23b72f99aacea 494 Pfam PF03703 Bacterial PH domain 253 331 1.3E-10 T 12-10-2018 IPR005182 Domain of unknown function DUF304 HW35_11290 1e40739ce9946b8a91a23b72f99aacea 494 Pfam PF03703 Bacterial PH domain 407 484 1.0E-8 T 12-10-2018 IPR005182 Domain of unknown function DUF304 HW35_12420 31cfe1c0a9a5e2bccdcf29c986fd495f 186 SUPERFAMILY SSF48295 36 118 5.02E-15 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HW35_12420 31cfe1c0a9a5e2bccdcf29c986fd495f 186 Pfam PF13518 Helix-turn-helix domain 66 118 5.2E-6 T 12-10-2018 HW35_06980 2278feac99a5608184679810ca97bda7 145 Pfam PF01934 Protein of unknown function DUF86 26 128 2.1E-19 T 12-10-2018 IPR008201 Protein of unknown function DUF86 HW35_06980 2278feac99a5608184679810ca97bda7 145 Gene3D G3DSA:1.20.120.580 1 144 1.8E-55 T 12-10-2018 IPR037038 Bsu32300-like superfamily HW35_05205 46d3fe59c7a12ae8f13aa52aff819d02 92 Pfam PF01527 Transposase 1 74 4.4E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_05205 46d3fe59c7a12ae8f13aa52aff819d02 92 Gene3D G3DSA:1.10.10.60 8 86 5.6E-9 T 12-10-2018 HW35_05205 46d3fe59c7a12ae8f13aa52aff819d02 92 SUPERFAMILY SSF46689 4 89 1.88E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_00330 46d3fe59c7a12ae8f13aa52aff819d02 92 Pfam PF01527 Transposase 1 74 4.4E-17 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HW35_00330 46d3fe59c7a12ae8f13aa52aff819d02 92 Gene3D G3DSA:1.10.10.60 8 86 5.6E-9 T 12-10-2018 HW35_00330 46d3fe59c7a12ae8f13aa52aff819d02 92 SUPERFAMILY SSF46689 4 89 1.88E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_11670 1d3e3aac537b0f0a439e4c35362759b1 180 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 114 166 1.3E-8 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 HW35_11670 1d3e3aac537b0f0a439e4c35362759b1 180 Hamap MF_01515 UPF0316 protein . 6 174 31.872 T 12-10-2018 IPR022930 Protein of unknown function UPF0316 HW35_15425 3a4202a4896959e1ee86f05e40427102 183 Pfam PF10612 Spore coat protein Z 1 176 2.5E-40 T 12-10-2018 IPR019593 Spore coat protein Z/Y HW35_08620 da3fec92df92167b8d7948ae96b0684d 238 Pfam PF02754 Cysteine-rich domain 131 215 1.4E-16 T 12-10-2018 IPR004017 Cysteine-rich domain HW35_08620 da3fec92df92167b8d7948ae96b0684d 238 Pfam PF02754 Cysteine-rich domain 3 84 1.9E-17 T 12-10-2018 IPR004017 Cysteine-rich domain HW35_08620 da3fec92df92167b8d7948ae96b0684d 238 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 63.169 T 12-10-2018 IPR022822 Lactate utilization protein A GO:0006089 HW35_17330 df12f4ec66851e93628df3346064d815 275 PIRSF PIRSF000090 2 268 1.6E-84 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 HW35_17330 df12f4ec66851e93628df3346064d815 275 Pfam PF01012 Electron transfer flavoprotein domain 24 207 1.0E-44 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HW35_17330 df12f4ec66851e93628df3346064d815 275 SUPERFAMILY SSF52402 2 262 2.81E-71 T 12-10-2018 HW35_17330 df12f4ec66851e93628df3346064d815 275 Gene3D G3DSA:3.40.50.620 2 268 3.6E-85 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HW35_17330 df12f4ec66851e93628df3346064d815 275 SMART SM00893 23 219 1.8E-53 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HW35_17000 e934f0d0b41068695ce91e52911407eb 265 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 262 6.0E-109 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like HW35_17000 e934f0d0b41068695ce91e52911407eb 265 PIRSF PIRSF004789 1 264 8.7E-106 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like HW35_17000 e934f0d0b41068695ce91e52911407eb 265 Gene3D G3DSA:3.60.21.10 1 265 1.0E-115 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like HW35_17000 e934f0d0b41068695ce91e52911407eb 265 SUPERFAMILY SSF56300 1 257 1.98E-90 T 12-10-2018 HW35_17000 e934f0d0b41068695ce91e52911407eb 265 Pfam PF13277 YmdB-like protein 4 255 6.6E-112 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like HW35_01345 001938907bcb5df9a6e4ac9aa10c8240 254 Gene3D G3DSA:1.10.3720.10 54 244 1.8E-24 T 12-10-2018 IPR035906 MetI-like superfamily HW35_01345 001938907bcb5df9a6e4ac9aa10c8240 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 245 5.0E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_01345 001938907bcb5df9a6e4ac9aa10c8240 254 SUPERFAMILY SSF161098 53 233 2.09E-30 T 12-10-2018 IPR035906 MetI-like superfamily HW35_07985 9246cc7f920b0dc81e9f35170d41f3bc 482 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 323 460 1.4E-26 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HW35_07985 9246cc7f920b0dc81e9f35170d41f3bc 482 Pfam PF01943 Polysaccharide biosynthesis protein 5 267 2.0E-23 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HW35_00165 ab3a10c73f286194307194ada13dbb74 532 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 42 500 8.4E-199 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HW35_00165 ab3a10c73f286194307194ada13dbb74 532 PIRSF PIRSF005690 27 515 1.2E-190 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HW35_17255 d6ec5346ba771efb9dd48c3a3f0bc872 235 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 10 214 1.1E-63 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 HW35_16110 d3904bc7798d888eef5c10bacb0b053b 111 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 31 101 8.3E-13 T 12-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 HW35_16110 d3904bc7798d888eef5c10bacb0b053b 111 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 4 111 2.7E-51 T 12-10-2018 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 HW35_04430 0aee358508fbaa083b6ad411232c7bde 269 Pfam PF03618 Kinase/pyrophosphorylase 6 261 1.5E-100 T 12-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 HW35_04430 0aee358508fbaa083b6ad411232c7bde 269 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 266 63.057 T 12-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein HW35_15075 81d487bed2013beba26eca1d5c6ca7a7 72 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 5.1E-28 T 12-10-2018 IPR019618 Spore germination protein GerPA/GerPF HW35_02790 ebc7768c7465f6ecf824317fbf969b66 192 SUPERFAMILY SSF52833 30 191 6.81E-41 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_02790 ebc7768c7465f6ecf824317fbf969b66 192 Gene3D G3DSA:3.40.30.10 21 191 2.4E-53 T 12-10-2018 HW35_02790 ebc7768c7465f6ecf824317fbf969b66 192 Pfam PF02630 SCO1/SenC 12 174 1.7E-42 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HW35_15595 8877fd33614c5a10483a553af55ff511 276 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 275 17.935 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HW35_15595 8877fd33614c5a10483a553af55ff511 276 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 268 4.4E-91 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HW35_15595 8877fd33614c5a10483a553af55ff511 276 Pfam PF02673 Bacitracin resistance protein BacA 9 270 4.7E-81 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HW35_06760 6df126bf5bb1a44fb3bb672133f1abb6 209 Pfam PF01810 LysE type translocator 12 201 1.5E-38 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 HW35_09870 ce6e3cea371e8a427609fa0151b096e4 404 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 79 1.2E-11 T 12-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HW35_09870 ce6e3cea371e8a427609fa0151b096e4 404 Pfam PF01610 Transposase 150 390 2.4E-70 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HW35_14330 15ca1cc17bdc8307a36b59f12491269b 291 Pfam PF14540 Nucleotidyltransferase-like 1 118 3.4E-47 T 12-10-2018 IPR029348 Nucleotidyltransferase-like domain HW35_14330 15ca1cc17bdc8307a36b59f12491269b 291 ProDom PD128250 YGXA BH0953 1 279 1.0E-99 T 12-10-2018 HW35_14330 15ca1cc17bdc8307a36b59f12491269b 291 Gene3D G3DSA:3.30.460.10 1 114 1.6E-43 T 12-10-2018 HW35_14330 15ca1cc17bdc8307a36b59f12491269b 291 Gene3D G3DSA:1.20.120.330 116 233 2.2E-50 T 12-10-2018 HW35_16790 7ba64f531d056dd4f1ed958626e8db19 262 Pfam PF01148 Cytidylyltransferase family 2 259 2.5E-75 T 12-10-2018 HW35_04070 1c6dacc3b31c1a2a763d0bb28ef4d196 165 Pfam PF11085 Conserved membrane protein YqhR 4 162 5.1E-59 T 12-10-2018 IPR024563 Uncharacterised protein family YqhR HW35_04070 1c6dacc3b31c1a2a763d0bb28ef4d196 165 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 41 155 3.0E-21 T 12-10-2018 IPR024563 Uncharacterised protein family YqhR HW35_01770 266c0ff9fad7b5fbb87cb58a3cf1cb55 279 Pfam PF02582 Uncharacterised ACR, YagE family COG1723 57 228 6.3E-27 T 12-10-2018 IPR003734 Domain of unknown function DUF155 HW35_11635 a3f366832453747c2d410be82fd3ac85 443 Pfam PF00860 Permease family 17 404 1.7E-44 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 HW35_11635 a3f366832453747c2d410be82fd3ac85 443 PIRSF PIRSF005353 1 443 4.8E-173 T 12-10-2018 IPR026033 Purine permease PbuG-like HW35_15275 ca4b42e6510d857ffb566336384f3716 569 Gene3D G3DSA:3.90.76.10 81 210 1.5E-119 T 12-10-2018 HW35_15275 ca4b42e6510d857ffb566336384f3716 569 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 99 480 2.0E-77 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain HW35_15275 ca4b42e6510d857ffb566336384f3716 569 SUPERFAMILY SSF53850 45 568 6.7E-116 T 12-10-2018 HW35_15275 ca4b42e6510d857ffb566336384f3716 569 Gene3D G3DSA:3.10.105.10 302 538 1.5E-119 T 12-10-2018 HW35_15275 ca4b42e6510d857ffb566336384f3716 569 Gene3D G3DSA:3.40.190.10 62 553 1.5E-119 T 12-10-2018 HW35_15275 ca4b42e6510d857ffb566336384f3716 569 PIRSF PIRSF002741 3 569 4.4E-95 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HW35_01210 61371f486e7123d4168b7795851b7d6b 354 Pfam PF00296 Luciferase-like monooxygenase 4 302 4.2E-51 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 HW35_01210 61371f486e7123d4168b7795851b7d6b 354 Gene3D G3DSA:3.20.20.30 1 351 3.1E-94 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 HW35_01210 61371f486e7123d4168b7795851b7d6b 354 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 2 339 2.3E-161 T 12-10-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative HW35_01210 61371f486e7123d4168b7795851b7d6b 354 SUPERFAMILY SSF51679 2 340 1.05E-83 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 HW35_04655 052a1ef657b7b661a748278a4cc2835e 371 Gene3D G3DSA:3.40.50.300 58 226 1.5E-50 T 12-10-2018 HW35_04655 052a1ef657b7b661a748278a4cc2835e 371 Pfam PF01926 50S ribosome-binding GTPase 164 226 3.2E-14 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 HW35_04655 052a1ef657b7b661a748278a4cc2835e 371 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 8 371 5.0E-158 T 12-10-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH HW35_04655 052a1ef657b7b661a748278a4cc2835e 371 SUPERFAMILY SSF52540 72 275 3.73E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_16440 892c93904de91a6af4b6928017fb811a 96 Gene3D G3DSA:1.20.120.910 1 80 1.0E-9 T 12-10-2018 HW35_00675 9d8510069751cd46ec50b16beb0e3586 217 Pfam PF02581 Thiamine monophosphate synthase 10 193 6.6E-59 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00675 9d8510069751cd46ec50b16beb0e3586 217 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 8 211 28.153 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00675 9d8510069751cd46ec50b16beb0e3586 217 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 9 204 6.1E-63 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_00675 9d8510069751cd46ec50b16beb0e3586 217 Gene3D G3DSA:3.20.20.70 1 216 4.7E-73 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_00675 9d8510069751cd46ec50b16beb0e3586 217 SUPERFAMILY SSF51391 7 211 2.35E-66 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HW35_04565 c485d3948a5f58b2b0441c81cad28b06 104 Pfam PF12438 Protein of unknown function (DUF3679) 7 56 7.8E-17 T 12-10-2018 IPR020534 Uncharacterised protein family YqxA HW35_04565 c485d3948a5f58b2b0441c81cad28b06 104 ProDom PD072942 YQXA ORF79 1 102 3.0E-20 T 12-10-2018 IPR020534 Uncharacterised protein family YqxA HW35_10935 c404d6f93000677bf68b94c34036cb35 399 Pfam PF12704 MacB-like periplasmic core domain 21 234 7.5E-34 T 12-10-2018 IPR025857 MacB-like periplasmic core domain HW35_10935 c404d6f93000677bf68b94c34036cb35 399 Pfam PF02687 FtsX-like permease family 305 392 2.4E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HW35_12025 f71b693ce6de15f1b0c6321e8be84d0b 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 79 3.8E-14 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain HW35_12025 f71b693ce6de15f1b0c6321e8be84d0b 107 Gene3D G3DSA:3.30.70.100 1 107 5.8E-39 T 12-10-2018 HW35_12025 f71b693ce6de15f1b0c6321e8be84d0b 107 SUPERFAMILY SSF54909 1 92 9.79E-22 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel HW35_04245 3945f2d8aa4c1baab33ef3d256c10acc 68 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 60 1.1E-29 T 12-10-2018 IPR009256 Protein of unknown function DUF910 HW35_04245 3945f2d8aa4c1baab33ef3d256c10acc 68 Gene3D G3DSA:1.10.287.760 1 68 3.1E-29 T 12-10-2018 IPR023164 YqgQ-like superfamily HW35_04245 3945f2d8aa4c1baab33ef3d256c10acc 68 SUPERFAMILY SSF158379 1 60 6.02E-24 T 12-10-2018 IPR023164 YqgQ-like superfamily HW35_07460 891660c9f4e5a907ea2e4517f4dba747 359 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 197 342 7.6E-8 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 HW35_07460 891660c9f4e5a907ea2e4517f4dba747 359 TIGRFAM TIGR03590 PseG: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase 1 298 1.1E-95 T 12-10-2018 IPR020023 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase HW35_07460 891660c9f4e5a907ea2e4517f4dba747 359 SUPERFAMILY SSF53756 16 341 1.39E-14 T 12-10-2018 HW35_07460 891660c9f4e5a907ea2e4517f4dba747 359 Gene3D G3DSA:3.40.50.11190 1 169 2.6E-49 T 12-10-2018 HW35_07460 891660c9f4e5a907ea2e4517f4dba747 359 Gene3D G3DSA:3.40.50.2000 170 314 3.0E-38 T 12-10-2018 HW35_04845 d995db44f72e0d72fa69a7077eb4f6cb 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 315 2.8E-53 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 HW35_05300 bd3f1bb0284482166d3e056e50c359fb 434 Pfam PF03553 Na+/H+ antiporter family 225 419 6.4E-13 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 HW35_05300 bd3f1bb0284482166d3e056e50c359fb 434 Pfam PF03553 Na+/H+ antiporter family 13 208 3.8E-15 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 HW35_08765 f7c4ccbe0621d049619bc5ccfe22767b 83 Pfam PF13751 Transposase DDE domain 3 43 1.3E-9 T 12-10-2018 IPR025668 Transposase DDE domain HW35_03015 a6ae80322d3ed2cf87a841fa8aabd0d7 363 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 224 360 7.4E-20 T 12-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal HW35_03015 a6ae80322d3ed2cf87a841fa8aabd0d7 363 PIRSF PIRSF000451 1 363 2.6E-117 T 12-10-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 HW35_03015 a6ae80322d3ed2cf87a841fa8aabd0d7 363 Gene3D G3DSA:3.40.47.10 1 212 5.0E-63 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_03015 a6ae80322d3ed2cf87a841fa8aabd0d7 363 SUPERFAMILY SSF53901 5 362 4.26E-47 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_03015 a6ae80322d3ed2cf87a841fa8aabd0d7 363 Gene3D G3DSA:3.40.47.10 219 362 1.5E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 HW35_03015 a6ae80322d3ed2cf87a841fa8aabd0d7 363 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 4 206 3.4E-17 T 12-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal HW35_02895 6a4598dac70431dd576b366a79ba0dcc 144 Gene3D G3DSA:3.40.30.10 25 144 5.9E-54 T 12-10-2018 HW35_02895 6a4598dac70431dd576b366a79ba0dcc 144 Pfam PF06491 Disulphide isomerase 8 144 1.4E-62 T 12-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family HW35_02895 6a4598dac70431dd576b366a79ba0dcc 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 144 5.4E-66 T 12-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family HW35_13420 6340c504adbfef73d9a6c954ef3d54cb 148 Pfam PF12821 Threonine/Serine exporter, ThrE 6 133 8.0E-39 T 12-10-2018 IPR024528 Threonine/Serine exporter, ThrE HW35_00785 af04ec547749465aab97d26688e9429c 105 Pfam PF01473 Putative cell wall binding repeat 3 21 1.4E-6 T 12-10-2018 IPR018337 Cell wall/choline-binding repeat HW35_00785 af04ec547749465aab97d26688e9429c 105 Pfam PF01473 Putative cell wall binding repeat 23 41 1.9E-7 T 12-10-2018 IPR018337 Cell wall/choline-binding repeat HW35_00785 af04ec547749465aab97d26688e9429c 105 Pfam PF01473 Putative cell wall binding repeat 43 61 2.9E-6 T 12-10-2018 IPR018337 Cell wall/choline-binding repeat HW35_00785 af04ec547749465aab97d26688e9429c 105 Pfam PF01473 Putative cell wall binding repeat 63 81 1.4E-6 T 12-10-2018 IPR018337 Cell wall/choline-binding repeat HW35_00785 af04ec547749465aab97d26688e9429c 105 Gene3D G3DSA:2.10.270.10 1 104 9.9E-38 T 12-10-2018 HW35_00785 af04ec547749465aab97d26688e9429c 105 SUPERFAMILY SSF69360 1 98 1.11E-38 T 12-10-2018 HW35_00540 6ef070100f8cb10f27209fe97f750163 294 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 25 262 3.5E-20 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 HW35_00540 6ef070100f8cb10f27209fe97f750163 294 PIRSF PIRSF003092 1 293 8.2E-79 T 12-10-2018 IPR025501 ATP binding protein MinD HW35_00540 6ef070100f8cb10f27209fe97f750163 294 SUPERFAMILY SSF52540 25 266 2.84E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_00540 6ef070100f8cb10f27209fe97f750163 294 Gene3D G3DSA:3.40.50.300 24 264 3.2E-53 T 12-10-2018 HW35_03050 5e611340d04bcd8816351e2539c17a87 77 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 7 75 2.4E-17 T 12-10-2018 IPR018720 Domain of unknown function DUF2249 HW35_05500 c9192a2a51f063a9c4754a31229a0ec5 86 Pfam PF05164 Cell division protein ZapA 9 82 1.5E-15 T 12-10-2018 IPR007838 Cell division protein ZapA-like HW35_05500 c9192a2a51f063a9c4754a31229a0ec5 86 SUPERFAMILY SSF102829 8 83 4.84E-19 T 12-10-2018 IPR036192 Cell division protein ZapA-like superfamily HW35_11620 b1b85c0034878dd5d2742fab07f4df50 218 SUPERFAMILY SSF103473 19 214 9.94E-5 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_09420 c66acee794ddeaae71795666ffe58066 339 Pfam PF00899 ThiF family 5 241 1.1E-60 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HW35_09420 c66acee794ddeaae71795666ffe58066 339 Gene3D G3DSA:3.40.50.720 1 250 7.5E-75 T 12-10-2018 HW35_09420 c66acee794ddeaae71795666ffe58066 339 SUPERFAMILY SSF69572 2 327 2.88E-84 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 HW35_02830 08c32736397b32dafacd6127b3884d94 245 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 8 219 6.4E-55 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HW35_02830 08c32736397b32dafacd6127b3884d94 245 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 147 175 1.2E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HW35_02830 08c32736397b32dafacd6127b3884d94 245 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 78 96 1.2E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HW35_02830 08c32736397b32dafacd6127b3884d94 245 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 1.2E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HW35_02830 08c32736397b32dafacd6127b3884d94 245 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 96 122 1.2E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HW35_02830 08c32736397b32dafacd6127b3884d94 245 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 3 233 15.127 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HW35_02830 08c32736397b32dafacd6127b3884d94 245 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 214 5.5E-56 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HW35_08175 c11df6ab72edfd69ae8e4a3d3564ff24 153 SUPERFAMILY SSF54427 39 152 7.6E-12 T 12-10-2018 IPR032710 NTF2-like domain superfamily HW35_05495 912d6e2b42496fddd65033b7a82199ac 180 Pfam PF02674 Colicin V production protein 2 164 4.0E-36 T 12-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 HW35_03765 c002e02055d546571b32b20cbc967b89 304 SUPERFAMILY SSF51569 3 289 3.81E-68 T 12-10-2018 HW35_03765 c002e02055d546571b32b20cbc967b89 304 Gene3D G3DSA:3.20.20.70 1 298 5.7E-113 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HW35_03765 c002e02055d546571b32b20cbc967b89 304 Pfam PF00682 HMGL-like 7 280 5.7E-48 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HW35_01050 b6e0cea24007bed865e4b22383f921ec 184 SUPERFAMILY SSF51735 2 83 5.91E-11 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily HW35_01050 b6e0cea24007bed865e4b22383f921ec 184 Gene3D G3DSA:3.40.50.720 1 90 8.1E-9 T 12-10-2018 HW35_01050 b6e0cea24007bed865e4b22383f921ec 184 Pfam PF00106 short chain dehydrogenase 2 82 2.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HW35_04195 55d7c47a325ebecb19aec1d47be54a8b 113 Gene3D G3DSA:3.30.700.10 12 113 5.0E-12 T 12-10-2018 HW35_04195 55d7c47a325ebecb19aec1d47be54a8b 113 SUPERFAMILY SSF54523 12 109 1.78E-15 T 12-10-2018 HW35_04195 55d7c47a325ebecb19aec1d47be54a8b 113 PRINTS PR00813 Bacterial general secretion pathway protein G signature 47 65 6.0E-9 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 HW35_04195 55d7c47a325ebecb19aec1d47be54a8b 113 PRINTS PR00813 Bacterial general secretion pathway protein G signature 11 36 6.0E-9 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 HW35_04195 55d7c47a325ebecb19aec1d47be54a8b 113 PIRSF PIRSF029928 1 103 1.5E-36 T 12-10-2018 IPR016940 ComG operon protein C GO:0030420 HW35_04195 55d7c47a325ebecb19aec1d47be54a8b 113 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 31 1.4E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_04195 55d7c47a325ebecb19aec1d47be54a8b 113 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 30 7.9E-8 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site HW35_04515 de4eb1fad4c17844be82edff52b42150 314 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 1 302 1.2E-67 T 12-10-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 HW35_04515 de4eb1fad4c17844be82edff52b42150 314 Pfam PF02690 Na+/Pi-cotransporter 13 145 4.1E-35 T 12-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 HW35_04515 de4eb1fad4c17844be82edff52b42150 314 Pfam PF02690 Na+/Pi-cotransporter 158 252 4.1E-18 T 12-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 HW35_04320 d2124eb390ffc38ada9189628f24f243 405 SUPERFAMILY SSF103473 17 400 5.62E-30 T 12-10-2018 IPR036259 MFS transporter superfamily HW35_04320 d2124eb390ffc38ada9189628f24f243 405 Pfam PF07690 Major Facilitator Superfamily 21 333 1.1E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HW35_04320 d2124eb390ffc38ada9189628f24f243 405 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HW35_04320 d2124eb390ffc38ada9189628f24f243 405 Gene3D G3DSA:1.20.1250.20 14 398 7.1E-24 T 12-10-2018 HW35_08940 5edd62538bb5a92e16b453d268d6d340 145 Pfam PF14183 YwpF-like protein 2 132 9.1E-45 T 12-10-2018 IPR025573 YwpF-like protein HW35_10140 041ee0212b89ddb9d061358b4d8458ab 67 Pfam PF10764 Inhibitor of sigma-G Gin 14 58 9.7E-20 T 12-10-2018 IPR019700 Anti-sigma-G factor Gin HW35_06955 751daa9121ce73ea8e2ee9c241a15e5a 78 SUPERFAMILY SSF117916 2 77 3.43E-27 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily HW35_06955 751daa9121ce73ea8e2ee9c241a15e5a 78 Pfam PF01106 NifU-like domain 10 75 4.5E-28 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 HW35_06955 751daa9121ce73ea8e2ee9c241a15e5a 78 Gene3D G3DSA:3.30.300.130 1 78 2.6E-33 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily HW35_06955 751daa9121ce73ea8e2ee9c241a15e5a 78 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 65 1.0E-22 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 HW35_08230 f93992a60bcd9eac3af796e22e47aa44 308 SUPERFAMILY SSF103481 40 142 6.02E-16 T 12-10-2018 HW35_08230 f93992a60bcd9eac3af796e22e47aa44 308 Pfam PF00892 EamA-like transporter family 6 139 2.6E-21 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_08230 f93992a60bcd9eac3af796e22e47aa44 308 Pfam PF00892 EamA-like transporter family 152 285 2.1E-25 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HW35_08230 f93992a60bcd9eac3af796e22e47aa44 308 SUPERFAMILY SSF103481 188 290 5.23E-14 T 12-10-2018 HW35_13870 52cc411c27851d4b2d8a6b6fd12e2022 107 Gene3D G3DSA:1.10.10.10 1 106 6.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HW35_13870 52cc411c27851d4b2d8a6b6fd12e2022 107 Pfam PF03551 Transcriptional regulator PadR-like family 10 81 7.4E-21 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal HW35_13870 52cc411c27851d4b2d8a6b6fd12e2022 107 SUPERFAMILY SSF46785 2 97 1.01E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HW35_13605 6c1498dca31d07fed8ac51559f159ce2 244 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 128 241 6.2E-40 T 12-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF HW35_13605 6c1498dca31d07fed8ac51559f159ce2 244 PIRSF PIRSF031509 4 244 3.9E-61 T 12-10-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 HW35_08775 7a6887ab24df86859a17faedc4082063 345 Pfam PF01610 Transposase 202 331 2.9E-37 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HW35_08775 7a6887ab24df86859a17faedc4082063 345 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 35 78 1.3E-12 T 12-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HW35_07000 394d24ddd05c8f462de7301dbb28d4e9 211 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 13 183 7.6E-29 T 12-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like HW35_13545 1bd74b8af0ea0f1d4e3fa9bcc1224440 362 Pfam PF05425 Copper resistance protein D 175 274 7.4E-11 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 HW35_05680 c3454c5e5a5a8c806f552f221390ae89 367 Pfam PF01594 AI-2E family transporter 15 352 1.8E-62 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like HW35_05680 c3454c5e5a5a8c806f552f221390ae89 367 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 11 355 5.8E-112 T 12-10-2018 IPR014227 Putative transport protein YtvI-like HW35_07225 497c25fa469ebc0c7290f702ce47a3c8 180 Gene3D G3DSA:2.40.50.140 94 176 1.5E-30 T 12-10-2018 HW35_08250 5bf5479afbcfb2cc27db9ec0819c4cfb 159 Pfam PF11188 Protein of unknown function (DUF2975) 33 159 3.2E-34 T 12-10-2018 IPR021354 Protein of unknown function DUF2975 HW35_04505 7e4f437020023eba631394e4229791ab 148 Pfam PF09424 Yqey-like protein 5 147 5.2E-55 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 HW35_04505 7e4f437020023eba631394e4229791ab 148 Gene3D G3DSA:1.10.10.410 92 148 1.5E-26 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal HW35_04505 7e4f437020023eba631394e4229791ab 148 SUPERFAMILY SSF89095 1 148 3.09E-44 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 HW35_04505 7e4f437020023eba631394e4229791ab 148 Gene3D G3DSA:1.10.1510.10 1 91 6.2E-31 T 12-10-2018 HW35_00340 d202e61509ede8d03e8a7eeed52b31a0 101 Pfam PF06124 Staphylococcal protein of unknown function (DUF960) 8 100 5.2E-24 T 12-10-2018 IPR009303 Protein of unknown function DUF960 HW35_00340 d202e61509ede8d03e8a7eeed52b31a0 101 Gene3D G3DSA:3.10.450.150 1 101 2.7E-8 T 12-10-2018 HW35_12375 3702a1dde22907d43c58ff0929a4db0b 734 SUPERFAMILY SSF52540 156 601 8.8E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HW35_12375 3702a1dde22907d43c58ff0929a4db0b 734 Pfam PF13087 AAA domain 399 583 2.2E-27 T 12-10-2018 HW35_12375 3702a1dde22907d43c58ff0929a4db0b 734 Gene3D G3DSA:3.40.50.300 104 386 5.5E-45 T 12-10-2018 HW35_12375 3702a1dde22907d43c58ff0929a4db0b 734 Pfam PF13086 AAA domain 157 368 2.9E-31 T 12-10-2018 HW35_12375 3702a1dde22907d43c58ff0929a4db0b 734 Gene3D G3DSA:3.40.50.300 408 619 2.8E-33 T 12-10-2018 HW35_02890 194429f8be8f9111f4cb332e05bfe343 193 Pfam PF02342 TerD domain 1 188 1.9E-83 T 12-10-2018 IPR003325 TerD domain HW35_02890 194429f8be8f9111f4cb332e05bfe343 193 Gene3D G3DSA:2.60.60.30 19 187 1.2E-69 T 12-10-2018 HW35_14520 796350d711fc6f70f3d83a08dd4d1870 502 SUPERFAMILY SSF53098 134 274 8.85E-7 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_14520 796350d711fc6f70f3d83a08dd4d1870 502 Pfam PF00665 Integrase core domain 133 254 5.1E-11 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_13330 2614562d071ea9d9cac59da14ea95ce4 99 SUPERFAMILY SSF57997 38 88 1.85E-6 T 12-10-2018 HW35_13330 2614562d071ea9d9cac59da14ea95ce4 99 Gene3D G3DSA:1.20.5.340 36 90 1.3E-5 T 12-10-2018 HW35_06610 d3902bc927d8e3ac05bead1502aee5b4 374 Pfam PF13242 HAD-hyrolase-like 284 369 2.3E-11 T 12-10-2018 HW35_06610 d3902bc927d8e3ac05bead1502aee5b4 374 Gene3D G3DSA:3.40.50.1000 202 374 2.0E-47 T 12-10-2018 IPR023214 HAD superfamily HW35_06610 d3902bc927d8e3ac05bead1502aee5b4 374 SUPERFAMILY SSF56784 2 374 9.58E-42 T 12-10-2018 IPR036412 HAD-like superfamily HW35_05160 e6dd8f1595e7c2bb8420681defd49d92 241 Pfam PF01478 Type IV leader peptidase family 95 198 1.8E-16 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 HW35_05160 e6dd8f1595e7c2bb8420681defd49d92 241 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 2 81 1.3E-29 T 12-10-2018 IPR010627 Peptidase A24A, N-terminal HW35_04010 b814473e97dd738ea80c44407593621e 219 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 30 219 4.9E-66 T 12-10-2018 IPR014195 Sporulation stage III, protein AG HW35_11305 396a757d48b158782aa171f321a9ef9b 191 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HW35_11305 396a757d48b158782aa171f321a9ef9b 191 SUPERFAMILY SSF46689 2 67 8.21E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_11305 396a757d48b158782aa171f321a9ef9b 191 Gene3D G3DSA:1.10.357.10 5 187 3.3E-18 T 12-10-2018 HW35_11305 396a757d48b158782aa171f321a9ef9b 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_11305 396a757d48b158782aa171f321a9ef9b 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_11305 396a757d48b158782aa171f321a9ef9b 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 1.7E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HW35_11175 9ec1daae126d34dd2338537d026c0f37 277 Pfam PF00665 Integrase core domain 117 228 9.3E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_11175 9ec1daae126d34dd2338537d026c0f37 277 SUPERFAMILY SSF53098 119 270 9.26E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_11175 9ec1daae126d34dd2338537d026c0f37 277 Pfam PF13276 HTH-like domain 34 87 2.2E-14 T 12-10-2018 IPR025948 HTH-like domain HW35_11175 9ec1daae126d34dd2338537d026c0f37 277 Gene3D G3DSA:3.30.420.10 115 258 1.3E-9 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HW35_04180 89f159704aeaaeadbd0cace4da2c5246 136 Pfam PF15980 Putative Competence protein ComGF 35 120 1.2E-20 T 12-10-2018 IPR016977 Competence operon G, ComGF HW35_04425 06a0d8279a335efc625f2aebbcee9998 148 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 144 27.931 T 12-10-2018 IPR003791 Protein of unknown function UPF0178 HW35_04425 06a0d8279a335efc625f2aebbcee9998 148 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 14 142 4.9E-38 T 12-10-2018 IPR003791 Protein of unknown function UPF0178 HW35_01060 6d46cceb72d2c0580cfb6f1f61549ff3 158 Gene3D G3DSA:1.10.8.1150 92 158 9.6E-8 T 12-10-2018 HW35_08760 7e9bdf0e9074547ee5b163b6c439d652 497 Pfam PF00665 Integrase core domain 151 249 1.1E-10 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 HW35_08760 7e9bdf0e9074547ee5b163b6c439d652 497 SUPERFAMILY SSF53098 155 269 6.57E-6 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily HW35_13435 23dd7c78afd9833762fa9e238e36d205 597 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 417 537 7.6E-29 T 12-10-2018 IPR025299 CstA, C-terminal domain HW35_13435 23dd7c78afd9833762fa9e238e36d205 597 Pfam PF02554 Carbon starvation protein CstA 1 370 2.5E-150 T 12-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 HW35_06645 216a884d70c877ba663e17f0e7806b37 237 Gene3D G3DSA:3.40.30.10 39 236 1.3E-44 T 12-10-2018 HW35_06645 216a884d70c877ba663e17f0e7806b37 237 SUPERFAMILY SSF52833 51 231 2.63E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_06645 216a884d70c877ba663e17f0e7806b37 237 Pfam PF13462 Thioredoxin 58 232 9.0E-32 T 12-10-2018 IPR012336 Thioredoxin-like fold HW35_04960 78cc37c7bd825e043d34e0cad1a80a74 68 Pfam PF11146 Protein of unknown function (DUF2905) 6 64 3.7E-24 T 12-10-2018 IPR021320 Protein of unknown function DUF2905 HW35_16075 f337bbe12fa781d33694123fb5e2d06a 105 SUPERFAMILY SSF46689 3 99 3.4E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_05815 abe8800dcf6c47937b1a6adeb4401cc3 232 Pfam PF11167 Protein of unknown function (DUF2953) 135 186 5.6E-18 T 12-10-2018 IPR021338 Protein of unknown function DUF2953 HW35_07115 3e6133ffa4845366332a1634333aa6cc 126 SUPERFAMILY SSF55718 29 104 5.1E-5 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily HW35_07115 3e6133ffa4845366332a1634333aa6cc 126 Pfam PF02036 SCP-2 sterol transfer family 27 103 1.0E-5 T 12-10-2018 IPR003033 SCP2 sterol-binding domain HW35_02810 5a6b16e4e4b89381092c5d8736845c4e 192 SUPERFAMILY SSF51306 39 119 2.62E-8 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily HW35_02810 5a6b16e4e4b89381092c5d8736845c4e 192 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 104 115 2.1E-6 T 12-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 HW35_02810 5a6b16e4e4b89381092c5d8736845c4e 192 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 46 61 2.1E-6 T 12-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 HW35_02810 5a6b16e4e4b89381092c5d8736845c4e 192 Pfam PF00717 Peptidase S24-like 45 103 3.8E-8 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HW35_02810 5a6b16e4e4b89381092c5d8736845c4e 192 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 6 164 3.7E-45 T 12-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 HW35_01295 97faa394ae025263c7fa8a66515f9dbe 209 PIRSF PIRSF020606 2 205 1.9E-64 T 12-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 HW35_01295 97faa394ae025263c7fa8a66515f9dbe 209 Pfam PF09997 Predicted membrane protein (DUF2238) 42 183 1.8E-51 T 12-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 HW35_03660 07d5ebff3df18e5fa89454d57bc2c335 140 Pfam PF13782 Stage V sporulation protein AB 27 135 1.2E-31 T 12-10-2018 IPR020144 Stage V sporulation protein AB HW35_03660 07d5ebff3df18e5fa89454d57bc2c335 140 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 3 138 9.0E-38 T 12-10-2018 IPR020144 Stage V sporulation protein AB HW35_01040 40e54a14aa70e0e31592980795325ac4 154 Pfam PF12638 Staygreen protein 6 148 1.8E-44 T 12-10-2018 IPR024438 Staygreen protein HW35_07390 1f47aa8325bd5127be86f505a667fa66 404 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 79 1.2E-11 T 12-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HW35_07390 1f47aa8325bd5127be86f505a667fa66 404 Pfam PF01610 Transposase 150 390 1.0E-70 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HW35_13885 700e470f301c79764595cc468860d141 528 Pfam PF02652 L-lactate permease 14 518 1.9E-160 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HW35_13885 700e470f301c79764595cc468860d141 528 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 13 519 2.7E-157 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HW35_09030 020dec3378fd1839a4a7c62588f3c62a 501 Pfam PF00361 Proton-conducting membrane transporter 139 433 2.6E-68 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09030 020dec3378fd1839a4a7c62588f3c62a 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 250 274 1.5E-39 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09030 020dec3378fd1839a4a7c62588f3c62a 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 390 416 1.5E-39 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09030 020dec3378fd1839a4a7c62588f3c62a 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 338 357 1.5E-39 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09030 020dec3378fd1839a4a7c62588f3c62a 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 1.5E-39 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09030 020dec3378fd1839a4a7c62588f3c62a 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 175 199 1.5E-39 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09030 020dec3378fd1839a4a7c62588f3c62a 501 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 496 1.9E-137 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_02175 0703058f0358a268aad1642f1386c5db 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 9.3E-15 T 12-10-2018 IPR012452 Protein of unknown function DUF1657 HW35_07760 09646c64d5a50b2bc8c83820ac5c2a36 430 Gene3D G3DSA:3.40.190.10 155 415 1.7E-95 T 12-10-2018 HW35_07760 09646c64d5a50b2bc8c83820ac5c2a36 430 Pfam PF01547 Bacterial extracellular solute-binding protein 54 341 5.0E-49 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein HW35_07760 09646c64d5a50b2bc8c83820ac5c2a36 430 Gene3D G3DSA:3.40.190.10 61 364 1.7E-95 T 12-10-2018 HW35_07760 09646c64d5a50b2bc8c83820ac5c2a36 430 SUPERFAMILY SSF53850 21 426 8.98E-84 T 12-10-2018 HW35_16145 129785ae7868b2bea77510891a8d73c9 160 SUPERFAMILY SSF54637 52 160 3.59E-29 T 12-10-2018 IPR029069 HotDog domain superfamily HW35_16145 129785ae7868b2bea77510891a8d73c9 160 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 52 155 3.8E-19 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 HW35_16145 129785ae7868b2bea77510891a8d73c9 160 Gene3D G3DSA:3.10.129.10 1 160 6.6E-48 T 12-10-2018 HW35_16145 129785ae7868b2bea77510891a8d73c9 160 Pfam PF03061 Thioesterase superfamily 73 148 2.4E-14 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 HW35_14185 aaa2a615271398470ecea5c559ab87d7 62 Pfam PF14151 YfhD-like protein 1 57 7.2E-27 T 12-10-2018 IPR025435 YfhD-like protein HW35_14185 aaa2a615271398470ecea5c559ab87d7 62 ProDom PD053407 YFHD 1 44 3.0E-13 T 12-10-2018 HW35_15640 ab157e2790add25be81357e6998704e7 117 Pfam PF13045 Protein of unknown function (DUF3905) 12 94 8.5E-47 T 12-10-2018 IPR024999 Protein of unknown function DUF3905 HW35_07050 aed054737bf7469abc2933b7d8191c5b 98 Gene3D G3DSA:1.10.10.60 10 97 5.9E-10 T 12-10-2018 HW35_07050 aed054737bf7469abc2933b7d8191c5b 98 SUPERFAMILY SSF46689 5 96 1.22E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_07050 aed054737bf7469abc2933b7d8191c5b 98 Pfam PF13518 Helix-turn-helix domain 12 63 2.8E-10 T 12-10-2018 HW35_08995 642bc6a99809a680be4717671f508a4a 347 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 7 335 5.9E-129 T 12-10-2018 IPR014225 Sporulation stage II, protein D firmicutes HW35_08995 642bc6a99809a680be4717671f508a4a 347 Pfam PF08486 Stage II sporulation protein 66 175 2.6E-25 T 12-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal HW35_08995 642bc6a99809a680be4717671f508a4a 347 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 70 334 3.4E-75 T 12-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 HW35_06565 740a63b1979622ac6094d132b6ea3625 108 Pfam PF04341 Protein of unknown function, DUF485 19 102 1.4E-24 T 12-10-2018 IPR007436 Protein of unknown function DUF485 HW35_11235 09c3b28e33ed26f26266d785592211ec 190 Pfam PF14066 Protein of unknown function (DUF4256) 18 190 8.4E-97 T 12-10-2018 IPR025352 Protein of unknown function DUF4256 HW35_10170 a91d3ce1f5ce2ecc9829fe24ee6496c2 124 Pfam PF06156 Initiation control protein YabA 2 119 2.2E-33 T 12-10-2018 IPR010377 Initiation control protein YabA GO:0006260 HW35_10170 a91d3ce1f5ce2ecc9829fe24ee6496c2 124 Hamap MF_01159 Initiation-control protein YabA. 1 123 24.567 T 12-10-2018 IPR010377 Initiation control protein YabA GO:0006260 HW35_10170 a91d3ce1f5ce2ecc9829fe24ee6496c2 124 PIRSF PIRSF021439 1 124 1.5E-40 T 12-10-2018 IPR010377 Initiation control protein YabA GO:0006260 HW35_15960 6c48f7f1e5b0c5651552cc8db6c8da14 40 Pfam PF13790 SR1 protein 1 35 4.9E-16 T 12-10-2018 IPR025236 SR1 protein HW35_14715 bddf8e5993170293069fa35a1d8d2683 470 Pfam PF04293 SpoVR like protein 4 409 1.3E-165 T 12-10-2018 IPR007390 Sporulation stage V, protein R HW35_04740 fbf8d064e337364d3e7ab2c861c4673b 423 Gene3D G3DSA:2.40.30.10 335 423 3.6E-38 T 12-10-2018 HW35_04740 fbf8d064e337364d3e7ab2c861c4673b 423 ProSitePatterns PS01276 Peptidase family U32 signature. 179 197 - T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 HW35_04740 fbf8d064e337364d3e7ab2c861c4673b 423 Pfam PF01136 Peptidase family U32 94 324 1.9E-88 T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 HW35_04740 fbf8d064e337364d3e7ab2c861c4673b 423 Pfam PF16325 Peptidase family U32 C-terminal domain 340 420 2.0E-26 T 12-10-2018 IPR032525 Peptidase family U32, C-terminal HW35_11740 e30a207858c2306d74d2b709baacf23e 95 Pfam PF11127 Protein of unknown function (DUF2892) 4 65 9.6E-11 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 HW35_07080 26c6232a00d1e51b5c0b93e9efd1823f 283 Gene3D G3DSA:3.40.190.10 124 232 8.9E-94 T 12-10-2018 HW35_07080 26c6232a00d1e51b5c0b93e9efd1823f 283 Pfam PF03180 NLPA lipoprotein 43 281 1.0E-86 T 12-10-2018 IPR004872 Lipoprotein NlpA family HW35_07080 26c6232a00d1e51b5c0b93e9efd1823f 283 SUPERFAMILY SSF53850 42 281 2.23E-79 T 12-10-2018 HW35_07080 26c6232a00d1e51b5c0b93e9efd1823f 283 Gene3D G3DSA:3.40.190.10 45 279 8.9E-94 T 12-10-2018 HW35_07080 26c6232a00d1e51b5c0b93e9efd1823f 283 PIRSF PIRSF002854 1 283 3.9E-102 T 12-10-2018 IPR004872 Lipoprotein NlpA family HW35_15535 4984c86a82ca2012b6476e5d692bef9f 220 Pfam PF04893 Yip1 domain 17 205 3.1E-25 T 12-10-2018 IPR006977 Yip1 domain GO:0016020 HW35_13120 7f478f0ccff31e03b7bd16cb63f1adc2 155 Pfam PF06177 QueT transporter 1 148 1.6E-32 T 12-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 HW35_13120 7f478f0ccff31e03b7bd16cb63f1adc2 155 PIRSF PIRSF031501 1 155 8.7E-56 T 12-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 HW35_09120 d48752e0cbf3f7671c86ba927aeb2fbe 124 Pfam PF03899 ATP synthase I chain 10 105 2.4E-17 T 12-10-2018 IPR005598 ATP synthase protein I HW35_09120 d48752e0cbf3f7671c86ba927aeb2fbe 124 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 23 121 1.0E-27 T 12-10-2018 HW35_17380 16292fd178f950f881b30d93f160afb4 519 PIRSF PIRSF005690 19 504 3.9E-189 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HW35_17380 16292fd178f950f881b30d93f160afb4 519 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 34 491 1.2E-197 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HW35_14295 c59e25c5edce37b3d6364aa266a3a408 263 Pfam PF06182 ABC-2 family transporter protein 31 262 1.4E-22 T 12-10-2018 IPR010390 Protein of unknown function DUF990 HW35_01710 e9d8777b552f9394d363f141c6f8aafd 86 TIGRFAM TIGR03995 target_X_rSAM: putative rSAM target protein, CGCGG family 2 82 1.8E-32 T 12-10-2018 IPR023906 Radical SAM target protein, putative HW35_11665 9baa7a269a2002ce54ff1fb2a195f987 418 Gene3D G3DSA:2.120.10.30 193 415 4.1E-9 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like HW35_11665 9baa7a269a2002ce54ff1fb2a195f987 418 Gene3D G3DSA:2.120.10.30 21 183 2.8E-11 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like HW35_11665 9baa7a269a2002ce54ff1fb2a195f987 418 SUPERFAMILY SSF82171 44 386 7.19E-19 T 12-10-2018 HW35_11665 9baa7a269a2002ce54ff1fb2a195f987 418 Pfam PF07676 WD40-like Beta Propeller Repeat 48 75 9.5E-5 T 12-10-2018 IPR011659 WD40-like Beta Propeller HW35_07425 f14c3e865a282dbf855fc97369068518 87 Gene3D G3DSA:3.40.30.10 1 78 1.0E-22 T 12-10-2018 HW35_07425 f14c3e865a282dbf855fc97369068518 87 Pfam PF05768 Glutaredoxin-like domain (DUF836) 5 71 3.6E-18 T 12-10-2018 IPR008554 Glutaredoxin-like HW35_07425 f14c3e865a282dbf855fc97369068518 87 SUPERFAMILY SSF52833 2 80 1.21E-21 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_01635 b69ada69d7c22daa4ccf8e0c34e42f7f 205 Pfam PF11193 Protein of unknown function (DUF2812) 9 118 4.0E-32 T 12-10-2018 IPR021359 Protein of unknown function DUF2812 HW35_05790 b9eef31768046cb2c5e6d99a26cb46ab 280 Pfam PF12787 EcsC protein family 10 272 1.8E-54 T 12-10-2018 IPR024787 EcsC protein HW35_05790 b9eef31768046cb2c5e6d99a26cb46ab 280 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 11 275 2.0E-6 T 12-10-2018 HW35_00190 25c66cbd337d684bd94567f8929bc4a8 287 Pfam PF13527 Acetyltransferase (GNAT) domain 6 137 6.5E-13 T 12-10-2018 HW35_00190 25c66cbd337d684bd94567f8929bc4a8 287 Gene3D G3DSA:3.40.630.30 13 259 9.9E-23 T 12-10-2018 HW35_00190 25c66cbd337d684bd94567f8929bc4a8 287 SUPERFAMILY SSF55729 3 284 6.05E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_16620 21803ea61b41c3d75b9c0070d71564c0 294 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 289 1.4E-143 T 12-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 HW35_16620 21803ea61b41c3d75b9c0070d71564c0 294 Pfam PF03313 Serine dehydratase alpha chain 15 274 4.5E-77 T 12-10-2018 IPR005130 Serine dehydratase-like, alpha subunit HW35_11405 36316eaa2f79389599e51fda3849d03b 193 Pfam PF01694 Rhomboid family 55 190 2.5E-36 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HW35_11405 36316eaa2f79389599e51fda3849d03b 193 SUPERFAMILY SSF144091 12 190 3.14E-40 T 12-10-2018 HW35_11405 36316eaa2f79389599e51fda3849d03b 193 Gene3D G3DSA:1.20.1540.10 10 193 2.9E-40 T 12-10-2018 IPR035952 Rhomboid-like superfamily HW35_12140 75e1360a5b24e3c2446640602087627e 240 Gene3D G3DSA:3.40.630.30 18 180 8.9E-6 T 12-10-2018 HW35_12140 75e1360a5b24e3c2446640602087627e 240 SUPERFAMILY SSF55729 24 192 1.1E-7 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase HW35_16025 6e15e2cc15abb5e398cd92cfdc05393c 107 Pfam PF14036 YlaH-like protein 18 93 2.4E-30 T 12-10-2018 IPR025620 YlaH-like protein HW35_03485 adeea849071e13f423e3c788dcec4560 76 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 5 69 6.0E-19 T 12-10-2018 IPR020256 Spore coat protein CotJA HW35_03485 adeea849071e13f423e3c788dcec4560 76 Pfam PF11007 Spore coat associated protein JA (CotJA) 28 63 5.4E-10 T 12-10-2018 IPR020256 Spore coat protein CotJA HW35_05480 d7835251ddccc9ba2521af692d49a525 135 Pfam PF03994 Domain of Unknown Function (DUF350) 15 65 3.1E-13 T 12-10-2018 IPR007140 Protein of unknown function DUF350 HW35_05480 d7835251ddccc9ba2521af692d49a525 135 Pfam PF03994 Domain of Unknown Function (DUF350) 80 134 2.0E-15 T 12-10-2018 IPR007140 Protein of unknown function DUF350 HW35_04985 866c27e93e8bf5750d35bccb76190864 325 SUPERFAMILY SSF56112 29 294 2.85E-21 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily HW35_04985 866c27e93e8bf5750d35bccb76190864 325 Gene3D G3DSA:3.90.1200.10 110 325 7.2E-18 T 12-10-2018 HW35_04985 866c27e93e8bf5750d35bccb76190864 325 Pfam PF01636 Phosphotransferase enzyme family 176 245 3.3E-9 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase HW35_08245 e16ff0da6bdac048341d29b2b8b63857 159 Pfam PF11188 Protein of unknown function (DUF2975) 34 148 7.7E-22 T 12-10-2018 IPR021354 Protein of unknown function DUF2975 HW35_14170 a56a31b05e98a775c82c9bca09d58da4 285 SUPERFAMILY SSF56317 3 271 1.1E-55 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily HW35_14170 a56a31b05e98a775c82c9bca09d58da4 285 Pfam PF00795 Carbon-nitrogen hydrolase 4 265 1.2E-29 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 HW35_14170 a56a31b05e98a775c82c9bca09d58da4 285 Gene3D G3DSA:3.60.110.10 1 284 6.7E-59 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily HW35_14170 a56a31b05e98a775c82c9bca09d58da4 285 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 149 169 - T 12-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site HW35_07265 ccdcc86345276bb295e1e748cfbf8faf 333 Gene3D G3DSA:1.20.1260.10 167 316 4.5E-13 T 12-10-2018 IPR012347 Ferritin-like HW35_07265 ccdcc86345276bb295e1e748cfbf8faf 333 Gene3D G3DSA:1.20.1260.10 3 146 1.6E-8 T 12-10-2018 IPR012347 Ferritin-like HW35_07265 ccdcc86345276bb295e1e748cfbf8faf 333 Pfam PF11553 Protein of unknown function (DUF3231) 5 160 1.2E-41 T 12-10-2018 IPR021617 Protein of unknown function DUF3231 HW35_07265 ccdcc86345276bb295e1e748cfbf8faf 333 Pfam PF11553 Protein of unknown function (DUF3231) 169 329 3.5E-36 T 12-10-2018 IPR021617 Protein of unknown function DUF3231 HW35_01595 f550d8f3d3e03be9b9ce83fa08eaa62d 299 Pfam PF08378 Nuclease-related domain 101 231 7.7E-14 T 12-10-2018 IPR011528 Nuclease-related domain, NERD HW35_12695 1c9d0f7f884813a387d36fca9d0a85fe 304 Gene3D G3DSA:3.40.1390.30 53 283 1.0E-29 T 12-10-2018 HW35_12695 1c9d0f7f884813a387d36fca9d0a85fe 304 SUPERFAMILY SSF102705 53 302 1.16E-39 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily HW35_12695 1c9d0f7f884813a387d36fca9d0a85fe 304 Gene3D G3DSA:3.40.1390.30 134 273 1.0E-29 T 12-10-2018 HW35_12695 1c9d0f7f884813a387d36fca9d0a85fe 304 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 54 290 1.2E-31 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HW35_12610 42803db3a886675d4627c8527187c6e8 207 SUPERFAMILY SSF53335 3 187 2.28E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HW35_12610 42803db3a886675d4627c8527187c6e8 207 Pfam PF08241 Methyltransferase domain 42 133 1.1E-17 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 HW35_12610 42803db3a886675d4627c8527187c6e8 207 Gene3D G3DSA:3.40.50.150 24 199 3.8E-31 T 12-10-2018 HW35_15775 819f163eaadfe868adca812b8db27c2a 63 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 2 57 1.0E-30 T 12-10-2018 IPR018690 Protein of unknown function DUF2187 HW35_08845 354450a45f10e3e3dfa43758491c8c74 257 SUPERFAMILY SSF52266 93 255 2.68E-10 T 12-10-2018 HW35_08845 354450a45f10e3e3dfa43758491c8c74 257 Gene3D G3DSA:3.40.50.1110 58 255 3.9E-12 T 12-10-2018 IPR036514 SGNH hydrolase superfamily HW35_04760 2325aa66c779deab874152cbf9f3a386 100 Hamap MF_01448 UPF0473 protein . 9 95 20.879 T 12-10-2018 IPR009711 Uncharacterised protein family UPF0473 HW35_04760 2325aa66c779deab874152cbf9f3a386 100 Pfam PF06949 Protein of unknown function (DUF1292) 18 92 9.1E-14 T 12-10-2018 IPR009711 Uncharacterised protein family UPF0473 HW35_07475 b914124402f67b134b7865c34846ba31 482 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 253 478 2.6E-5 T 12-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 HW35_07475 b914124402f67b134b7865c34846ba31 482 SUPERFAMILY SSF53756 176 478 4.93E-19 T 12-10-2018 HW35_01765 217878ed63d05fcc5b019ac58c4c7a8e 206 Pfam PF07486 Cell Wall Hydrolase 107 204 9.0E-27 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 HW35_01765 217878ed63d05fcc5b019ac58c4c7a8e 206 Gene3D G3DSA:1.10.10.2520 90 168 5.4E-30 T 12-10-2018 HW35_01765 217878ed63d05fcc5b019ac58c4c7a8e 206 Gene3D G3DSA:2.40.10.420 173 206 7.1E-12 T 12-10-2018 HW35_03655 d08da7e256a0a880087ee8165da4f526 199 Pfam PF14097 Stage V sporulation protein AE1 6 185 9.0E-83 T 12-10-2018 IPR025914 Stage V sporulation protein AE HW35_06190 d461bb5dd8fe244cf8494b020ef25e7a 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 265 5.4E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HW35_06190 d461bb5dd8fe244cf8494b020ef25e7a 268 SUPERFAMILY SSF161098 72 258 6.41E-29 T 12-10-2018 IPR035906 MetI-like superfamily HW35_06190 d461bb5dd8fe244cf8494b020ef25e7a 268 Gene3D G3DSA:1.10.3720.10 72 268 2.2E-23 T 12-10-2018 IPR035906 MetI-like superfamily HW35_15460 63ad96b3b3b37569d3593cdbfefca31e 84 Pfam PF14069 Stage VI sporulation protein F 6 77 1.7E-27 T 12-10-2018 IPR025942 Stage VI sporulation protein F HW35_12165 bba4faab5c40ecf6181098bf8008926c 244 Pfam PF01925 Sulfite exporter TauE/SafE 7 237 9.8E-38 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HW35_02815 f592e7253dabbf9e479dd88788516a02 265 TIGRFAM TIGR04087 YqxM_for_SipW: YqxM protein 5 179 2.0E-45 T 12-10-2018 IPR023848 TasA anchoring/assembly protein GO:0062039 HW35_01395 5ec41fe831541418e0570c32ba1cdd34 432 Pfam PF07670 Nucleoside recognition 120 219 4.9E-8 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HW35_05060 58d1f17a5642394096bd42a9b13426da 288 Pfam PF02163 Peptidase family M50 34 103 4.7E-8 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 HW35_11285 e48e3e1a82d3260c3a3759a009de3dd2 164 Pfam PF03703 Bacterial PH domain 77 153 8.2E-17 T 12-10-2018 IPR005182 Domain of unknown function DUF304 HW35_03920 6ef1dad7dc76a1e8280d7cb813e935f1 77 Pfam PF11118 Protein of unknown function (DUF2627) 2 77 4.3E-37 T 12-10-2018 IPR020138 Uncharacterised protein family YqzF HW35_03920 6ef1dad7dc76a1e8280d7cb813e935f1 77 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 1 77 6.0E-15 T 12-10-2018 IPR020138 Uncharacterised protein family YqzF HW35_07330 e6a319d9610a128996a25750c1891437 166 Pfam PF02535 ZIP Zinc transporter 21 153 4.3E-14 T 12-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 HW35_07915 d3490a2163832bac5c5b00c0473d3759 353 Pfam PF00953 Glycosyl transferase family 4 70 225 2.0E-40 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 HW35_07915 d3490a2163832bac5c5b00c0473d3759 353 ProSitePatterns PS01348 MraY family signature 2. 145 156 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_05520 ef2b6dbad57015227eb24c69a558a68d 83 Pfam PF05114 Protein of unknown function (DUF692) 1 62 3.0E-10 T 12-10-2018 IPR007801 Uncharacterised protein family UPF0276 HW35_05520 ef2b6dbad57015227eb24c69a558a68d 83 Gene3D G3DSA:3.20.20.150 1 76 1.6E-8 T 12-10-2018 HW35_17275 06895385395ed9fed4413be29bc217be 141 ProDom PD086666 YNEK BH2332 18 141 3.0E-46 T 12-10-2018 IPR020203 Uncharacterised protein family, YneK HW35_17275 06895385395ed9fed4413be29bc217be 141 Pfam PF11084 Protein of unknown function (DUF2621) 4 141 7.9E-72 T 12-10-2018 IPR020203 Uncharacterised protein family, YneK HW35_07700 566b6a11bcf3f1002b4e251f2e45f454 120 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 106 5.8E-25 T 12-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV HW35_00995 80efadf3a342fbf2dfb53668aca4279c 76 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 7 72 3.2E-30 T 12-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like HW35_00995 80efadf3a342fbf2dfb53668aca4279c 76 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 76 28.212 T 12-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like HW35_09025 e4dbaad6411abf2f7970dd39fe763363 503 Pfam PF00361 Proton-conducting membrane transporter 131 437 2.6E-70 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09025 e4dbaad6411abf2f7970dd39fe763363 503 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 9 488 17.525 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 HW35_09025 e4dbaad6411abf2f7970dd39fe763363 503 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 13 487 1.1E-120 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 HW35_03650 e4f4a6cff639b203e721c31b147ee6bd 491 PIRSF PIRSF005690 6 491 2.2E-132 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HW35_03650 e4f4a6cff639b203e721c31b147ee6bd 491 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 18 476 5.6E-147 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HW35_05960 08f4c7468587c26bee4ea4d20324274c 104 Pfam PF00085 Thioredoxin 11 100 9.2E-17 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 HW35_05960 08f4c7468587c26bee4ea4d20324274c 104 Gene3D G3DSA:3.40.30.10 1 102 1.6E-23 T 12-10-2018 HW35_05960 08f4c7468587c26bee4ea4d20324274c 104 SUPERFAMILY SSF52833 3 101 7.87E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily HW35_16280 fde9c9ed8d17a71c1bcf7ce33a14181e 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 58.814 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HW35_16280 fde9c9ed8d17a71c1bcf7ce33a14181e 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 143 4.4E-60 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HW35_16280 fde9c9ed8d17a71c1bcf7ce33a14181e 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 1.7E-21 T 12-10-2018 IPR020603 MraZ domain HW35_16280 fde9c9ed8d17a71c1bcf7ce33a14181e 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 141 4.4E-27 T 12-10-2018 IPR020603 MraZ domain HW35_16280 fde9c9ed8d17a71c1bcf7ce33a14181e 143 SUPERFAMILY SSF89447 1 136 4.11E-52 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily HW35_16280 fde9c9ed8d17a71c1bcf7ce33a14181e 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 4.0E-51 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HW35_16280 fde9c9ed8d17a71c1bcf7ce33a14181e 143 Gene3D G3DSA:2.40.330.20 1 141 5.9E-53 T 12-10-2018 IPR038619 MraZ superfamily HW35_03605 9f7b0d8a763441eaa74976427db7de2a 162 Pfam PF13047 Protein of unknown function (DUF3907) 11 156 1.1E-64 T 12-10-2018 IPR025013 Protein of unknown function DUF3907 HW35_07305 21dbcefa455736dded630c5f4aeb8b68 506 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 33 490 5.1E-139 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HW35_07305 21dbcefa455736dded630c5f4aeb8b68 506 PIRSF PIRSF005690 19 506 6.8E-135 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HW35_12620 0ac2ae56d0f2c3b884086460d54d3aef 90 ProDom PD745092 MEMBRANE YHDT SODIUM/PANTOTHENATE TRANSMEMBRANE INNER SYMPORTER Y0210 INTEGRAL PROTEIN-LIKE PM1090 3 84 2.0E-27 T 12-10-2018 IPR010398 Protein of unknown function DUF997 HW35_12620 0ac2ae56d0f2c3b884086460d54d3aef 90 Pfam PF06196 Protein of unknown function (DUF997) 9 84 4.9E-29 T 12-10-2018 IPR010398 Protein of unknown function DUF997 HW35_02645 ace14aac6cee2e90a269e669db47b18e 158 Pfam PF13115 YtkA-like 33 112 5.5E-15 T 12-10-2018 IPR032693 YtkA-like domain HW35_06325 ca74f3abc61ec502003b9cad4dcc93c9 204 Pfam PF01810 LysE type translocator 14 197 6.8E-26 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 HW35_13100 b0ec87c95963dd89a6dc680b1a5fe166 169 Pfam PF07681 DoxX 16 114 1.4E-8 T 12-10-2018 IPR032808 DoxX family HW35_09860 0bb92bc7fa6a4f46ac2f32a0fb10b06a 314 Pfam PF09991 Predicted membrane protein (DUF2232) 15 302 1.8E-62 T 12-10-2018 IPR018710 Protein of unknown function DUF2232 HW35_14700 6d06627c82027e7372f6627a5aea6b9a 84 Pfam PF14148 YhdB-like protein 1 70 1.9E-39 T 12-10-2018 IPR025431 YhdB-like protein HW35_09540 06b067d678d0628f031dc39f6a402403 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 277 1.6E-45 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 HW35_08855 dffacf5949a9fe539b1c7e36e98cd010 186 Pfam PF13518 Helix-turn-helix domain 66 118 5.2E-6 T 12-10-2018 HW35_08855 dffacf5949a9fe539b1c7e36e98cd010 186 SUPERFAMILY SSF48295 36 118 5.02E-15 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HW35_09075 7b7022411be27d73a29046784354819b 124 Gene3D G3DSA:1.20.58.1610 3 124 2.5E-43 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_09075 7b7022411be27d73a29046784354819b 124 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 7 124 19.464 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 HW35_09075 7b7022411be27d73a29046784354819b 124 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 26 123 1.6E-38 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HW35_08815 e4e9b593beb9dffdb24deca5be1bdeb0 372 Gene3D G3DSA:3.40.50.2000 198 347 5.3E-21 T 12-10-2018 HW35_08815 e4e9b593beb9dffdb24deca5be1bdeb0 372 SUPERFAMILY SSF53756 140 369 6.28E-17 T 12-10-2018 HW35_08815 e4e9b593beb9dffdb24deca5be1bdeb0 372 Pfam PF13692 Glycosyl transferases group 1 241 338 7.2E-9 T 12-10-2018 HW35_02870 746d91de25bc5e1fb06b80df1af8e1e1 366 PIRSF PIRSF026508 5 365 6.2E-125 T 12-10-2018 IPR008863 Toxic anion resistance HW35_02870 746d91de25bc5e1fb06b80df1af8e1e1 366 Pfam PF05816 Toxic anion resistance protein (TelA) 38 363 6.9E-110 T 12-10-2018 IPR008863 Toxic anion resistance HW35_04670 2df3046d55307dbb58d8006577691e63 260 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 48 209 6.6E-47 T 12-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 HW35_04670 2df3046d55307dbb58d8006577691e63 260 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 7 258 37.363 T 12-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 HW35_04670 2df3046d55307dbb58d8006577691e63 260 Pfam PF02666 Phosphatidylserine decarboxylase 59 255 6.3E-55 T 12-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 HW35_15290 7db9b4342d220f0a1ce419b6515c0f93 248 Pfam PF12227 Protein of unknown function (DUF3603) 35 248 5.6E-115 T 12-10-2018 IPR020909 UPF0736 HW35_15290 7db9b4342d220f0a1ce419b6515c0f93 248 Hamap MF_01860 UPF0736 protein . 1 248 49.887 T 12-10-2018 IPR020909 UPF0736 HW35_08700 7044bdcdecaed805d84cec6574c3ff8d 72 Pfam PF11148 Protein of unknown function (DUF2922) 3 68 2.9E-22 T 12-10-2018 IPR021321 Protein of unknown function DUF2922 HW35_07260 4327d67d826b324f0ba0efd68b126af9 170 Pfam PF03061 Thioesterase superfamily 25 97 3.3E-14 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 HW35_07260 4327d67d826b324f0ba0efd68b126af9 170 Gene3D G3DSA:3.10.129.10 1 165 1.1E-60 T 12-10-2018 HW35_07260 4327d67d826b324f0ba0efd68b126af9 170 SUPERFAMILY SSF54637 1 154 4.55E-49 T 12-10-2018 IPR029069 HotDog domain superfamily HW35_02640 0a58c5487f111a49f4049416e6d6b1b7 157 Gene3D G3DSA:2.60.40.790 16 144 3.8E-6 T 12-10-2018 IPR008978 HSP20-like chaperone HW35_02640 0a58c5487f111a49f4049416e6d6b1b7 157 SUPERFAMILY SSF49764 64 153 2.54E-8 T 12-10-2018 IPR008978 HSP20-like chaperone HW35_09700 c11ed84dd8aeb187683aa4dd303128bb 244 Pfam PF02361 Cobalt transport protein 6 217 1.2E-33 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component HW35_16420 190294fe43d831c04ec5930f76a24aa2 87 Pfam PF02325 YGGT family 11 76 1.4E-25 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 HW35_04925 17fdadedf87e8c7a697fef47b5d89f51 98 Pfam PF13797 Post-transcriptional regulator 8 87 1.5E-28 T 12-10-2018 IPR025716 Post-transcriptional regulator HW35_13720 5d42fb8a6fe7ea235470bba0cd0d593f 145 SUPERFAMILY SSF46689 28 129 1.56E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HW35_08795 1e3712a0dd8e48356c35228d3ea9e8cb 411 Pfam PF04932 O-Antigen ligase 198 339 1.4E-9 T 12-10-2018 IPR007016 O-antigen ligase-related HW35_11625 763a0efd8b0c5cbd17276b0fd88c5279 250 Pfam PF01925 Sulfite exporter TauE/SafE 5 245 1.8E-40 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HW35_02965 06345e68b595e6606ca1ebc36f513f06 65 Pfam PF10782 Zinc-finger 6 61 1.8E-23 T 12-10-2018 IPR019718 Protein of unknown function DUF2602 HW35_10950 cc6a8631316aa9d6bc15d6968213ba58 362 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 361 6.0E-60 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HW35_10950 cc6a8631316aa9d6bc15d6968213ba58 362 Pfam PF03845 Spore germination protein 10 325 8.2E-87 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HW35_05580 c1b2614baf7469bea003520e65a27dc9 287 Pfam PF08812 YtxC-like family 56 267 5.1E-54 T 12-10-2018 IPR014199 Sporulation protein YtxC HW35_08595 c7bde4ddda31006a573bcc31863615b1 156 Pfam PF06338 ComK protein 5 148 1.7E-31 T 12-10-2018 IPR010461 Competence protein ComK GO:0030420 HW35_01390 554b0b1e96819c0a9348b7347ee3a72c 447 Pfam PF02667 Short chain fatty acid transporter 10 446 3.9E-125 T 12-10-2018 IPR006160 Short chain fatty acid transporter AtoE HW35_07525 ec1c06d3d1bc4c2170127c596676f822 124 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 5 112 1.3E-38 T 12-10-2018 IPR018745 Domain of unknown function DUF2294 HW35_06985 de88a17b983aa9d95d27df32f9b24a4b 88 Pfam PF11256 Protein of unknown function (DUF3055) 7 86 5.8E-39 T 12-10-2018 IPR021415 Protein of unknown function DUF3055 HW35_01150 ff4b8b088a3547ac6358ffd6c523faf9 538 Gene3D G3DSA:1.10.10.2840 395 525 1.5E-16 T 12-10-2018 HW35_01150 ff4b8b088a3547ac6358ffd6c523faf9 538 Pfam PF13556 PucR C-terminal helix-turn-helix domain 464 521 3.9E-18 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain HW35_01150 ff4b8b088a3547ac6358ffd6c523faf9 538 Pfam PF07905 Purine catabolism regulatory protein-like family 11 130 1.6E-36 T 12-10-2018 IPR012914 Purine catabolism PurC-like domain HW35_02020 f0b161babda76d0a88b6e9d240d01491 271 Pfam PF03618 Kinase/pyrophosphorylase 7 262 1.2E-99 T 12-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 HW35_02020 f0b161babda76d0a88b6e9d240d01491 271 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 5 267 61.286 T 12-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein HW35_10960 d5f314949b8c9e44ecca3deff0f6b7b6 147 Pfam PF10730 Protein of unknown function (DUF2521) 2 147 5.7E-59 T 12-10-2018 IPR019667 Uncharacterised protein family YbaK HW35_13600 0c74b08adfe3d461243c6e1f15958c77 214 Pfam PF04012 PspA/IM30 family 3 208 2.3E-19 T 12-10-2018 IPR007157 PspA/IM30 HW35_14260 3453f67b18edc6ad8291cf1225518cc6 85 Pfam PF14182 YgaB-like protein 4 78 2.4E-33 T 12-10-2018 IPR025572 YgaB-like protein HW35_07960 55bcb551f7d68b15b86f789307981a6c 353 ProSitePatterns PS01348 MraY family signature 2. 145 156 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HW35_07960 55bcb551f7d68b15b86f789307981a6c 353 Pfam PF00953 Glycosyl transferase family 4 72 225 7.6E-42 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 HW35_14865 2705bca61087dffa227f66ae364e4827 61 Pfam PF14120 YhzD-like protein 1 60 3.0E-29 T 12-10-2018 IPR025544 YhzD-like protein HW35_03805 fec271b13331eabd02a201da532af949 63 Pfam PF14164 YqzH-like protein 1 63 2.1E-22 T 12-10-2018 IPR025546 YqzH-like protein HW35_06345 e5068bcf0ec54d93243148b48c53b0e5 60 Pfam PF12606 Tumour necrosis factor receptor superfamily member 19 11 49 5.9E-15 T 12-10-2018 IPR022248 TNF receptor family, RELT HW35_14810 5f69232f55cac3cb32f30e23e05a6d48 301 Gene3D G3DSA:1.10.10.2840 175 300 7.2E-13 T 12-10-2018 HW35_14810 5f69232f55cac3cb32f30e23e05a6d48 301 Pfam PF13556 PucR C-terminal helix-turn-helix domain 237 294 6.0E-16 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain HW35_15580 e6008b76e376b88260bd187b285e331d 214 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 39 188 1.7E-6 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT HW35_01070 c9fb75337ddc3dff8825eca5601d68b6 90 SUPERFAMILY SSF47240 20 73 5.95E-7 T 12-10-2018 IPR009078 Ferritin-like superfamily HW35_14670 fdddcef7f3a9b351a1835f6741116257 332 Pfam PF01384 Phosphate transporter family 22 321 8.2E-93 T 12-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 HW35_07990 266a037f9407fe3a9c1955c0330401c3 134 Pfam PF04138 GtrA-like protein 9 126 1.7E-25 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 HW35_17445 c17e0627899e05577c65510f132dc5cf 205 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 191 4.4E-41 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT HW35_15445 3f4dbee3a60a79ee225be2910318b39d 158 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 13 152 1.6E-63 T 12-10-2018 IPR014203 Sporulation stage V, protein AC HW35_15445 3f4dbee3a60a79ee225be2910318b39d 158 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 31 148 1.4E-38 T 12-10-2018 IPR005562 SpoVA HW35_08505 fa192c2d054455a6391fd73371f2cee7 72 Pfam PF07872 Protein of unknown function (DUF1659) 7 50 1.0E-16 T 12-10-2018 IPR012454 Protein of unknown function DUF1659 HW35_02195 87352a4fc998fe797484868747afaf4f 85 Pfam PF02096 60Kd inner membrane protein 30 70 9.5E-8 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HW35_11675 92b105cdcaca7c0aae1575dd4e92a82d 65 Pfam PF14044 NETI protein 7 62 2.2E-27 T 12-10-2018 IPR025930 NETI protein HW35_03385 6921e0708fb2524b8fa353ac36c5da2a 236 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 18 233 2.0E-80 T 12-10-2018 HW35_15725 af7a01ab8e46ffe22626d8721c661070 349 Pfam PF03845 Spore germination protein 9 314 2.6E-6 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HW35_14895 cdb97caa46579999e57525f765e07296 62 Pfam PF14147 Sporulation protein YhaL 3 54 2.6E-23 T 12-10-2018 IPR025428 Sporulation protein YhaL HW35_03570 4277a23f07c63f16f3c435a333bc0d19 541 Pfam PF05140 ResB-like family 436 516 2.4E-19 T 12-10-2018 IPR007816 ResB-like domain HW35_03570 4277a23f07c63f16f3c435a333bc0d19 541 Pfam PF05140 ResB-like family 66 423 1.1E-76 T 12-10-2018 IPR007816 ResB-like domain HW35_14545 8a2a5e03f661a5ba7f0835d1956d43ab 90 Pfam PF13828 Domain of unknown function (DUF4190) 11 73 3.2E-12 T 12-10-2018 IPR025241 Domain of unknown function DUF4190 HW35_03440 16aacc3d8e4469901cd99204870a2d95 61 Pfam PF17313 Family of unknown function (DUF5359) 1 56 7.0E-27 T 12-10-2018 IPR035281 Protein of unknown function DUF5359 HW35_15430 68313f1352e8793b15c5ba29582f3097 117 Pfam PF07098 Protein of unknown function (DUF1360) 10 110 8.3E-38 T 12-10-2018 IPR010773 Mycobacterium phage PG1, Gp7 HW35_17065 791da226387d42738e3ba1346e087c4f 132 Pfam PF07681 DoxX 5 92 1.9E-21 T 12-10-2018 IPR032808 DoxX family HW35_01715 72fe24370bf05902828fe42a63d98621 160 Pfam PF04306 Protein of unknown function (DUF456) 21 157 7.4E-38 T 12-10-2018 IPR007403 Protein of unknown function DUF456 HW35_00220 7ab660b1466d7c969a2cf1af3c8a88d5 146 Pfam PF03963 Flagellar hook capping protein - N-terminal region 13 76 2.1E-21 T 12-10-2018 IPR005648 Flagellar hook capping protein HW35_10630 79ff0fa39c93fdf0374e00e40bc7ffd1 169 Pfam PF05991 YacP-like NYN domain 4 166 3.9E-56 T 12-10-2018 IPR010298 Protein of unknown function DUF901 HW35_01075 3e8dc145a7ffc4e694fbe9b72e1be457 117 Pfam PF07875 Coat F domain 32 94 1.6E-18 T 12-10-2018 IPR012851 Spore coat protein CotF-like HW35_02875 e09aeb185b22d460261745fc9150e179 541 Pfam PF14266 Putative component of 'biosynthetic module' 72 524 2.5E-152 T 12-10-2018 IPR025647 Putative component of 'biosynthetic module' HW35_09340 2b11efd999adda731c554d3dea6623ab 216 Pfam PF02163 Peptidase family M50 120 179 3.3E-9 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 HW35_17315 34f109385d0bade5b4403fa3571109d7 60 Pfam PF13076 Fur-regulated basic protein A 8 43 1.6E-10 T 12-10-2018 IPR025072 Fur-regulated basic protein A HW35_05975 9c31ef4d89e4af1f28653ec21e4d8adf 107 Pfam PF03413 Peptidase propeptide and YPEB domain 29 100 2.3E-5 T 12-10-2018 IPR025711 PepSY domain HW35_06130 9404be9f46d43ca02cfd2584122034b4 92 Pfam PF10732 Protein of unknown function (DUF2524) 1 84 4.3E-33 T 12-10-2018 IPR019668 Uncharacterised protein family YtzC HW35_03160 6d606225a30b9883466c64485537918f 325 Pfam PF10720 Protein of unknown function (DUF2515) 12 312 1.6E-117 T 12-10-2018 IPR019658 Protein of unknown function DUF2515 HW35_04720 3d167605d6250952994dfc352e721008 226 Pfam PF07423 Protein of unknown function (DUF1510) 9 220 2.4E-65 T 12-10-2018 IPR009988 Protein of unknown function DUF1510 HW35_13590 1507318704e45803ac9fff05535a998a 121 Pfam PF07098 Protein of unknown function (DUF1360) 5 102 1.2E-30 T 12-10-2018 IPR010773 Mycobacterium phage PG1, Gp7 HW35_12720 e384e36b4197de6983b2228d196a21bc 69 Gene3D G3DSA:1.10.1660.10 8 55 1.1E-6 T 12-10-2018 HW35_03795 53c743ebf2d4f774cc225f44bb5eefdc 111 Pfam PF08863 YolD-like protein 14 107 6.7E-25 T 12-10-2018 IPR014962 YolD-like protein HW35_03295 f25782373c7c1d9f1cac286ac062fb50 154 Pfam PF10673 Protein of unknown function (DUF2487) 9 150 5.3E-52 T 12-10-2018 IPR019615 Protein of unknown function DUF2487 HW35_02765 0f25a8326d6642f2838abde8aa386b64 197 Pfam PF04367 Protein of unknown function (DUF502) 56 157 1.3E-27 T 12-10-2018 IPR007462 Protein of unknown function DUF502 HW35_05590 0150723535d74be3fa996addae0b8d16 463 Pfam PF07261 Replication initiation and membrane attachment 329 394 7.3E-13 T 12-10-2018 IPR006343 DnaD domain HW35_05720 bb0c80009226f610e8edcf03661253c0 112 Pfam PF14034 Sporulation protein YtrH 9 107 2.7E-40 T 12-10-2018 IPR025689 Sporulation protein YtrH HW35_10910 9f9c4ba42630664de0f6baff4dac90b2 175 Pfam PF01944 Stage II sporulation protein M 18 171 1.1E-19 T 12-10-2018 IPR002798 Stage II sporulation protein M-like