locus-tag class description EGX95_00080 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EGX95_00085 ENOG4108QY0 Membrane EGX95_00100 ENOG4105CZ3 stage V sporulation protein ad EGX95_00105 ENOG41090VF Stage v sporulation protein ac EGX95_00120 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EGX95_00150 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase EGX95_00165 ENOG41086D8 Transcriptional regulator EGX95_00195 ENOG4105VMP Transcriptional regulator EGX95_00215 ENOG4105E6M Sulphatase-modifying factor protein EGX95_00225 ENOG4107UCJ Catalyzes the synthesis of activated sulfate (By similarity) EGX95_00230 ENOG4107RIQ Sulfate adenylate transferase EGX95_00260 ENOG4105CKK Glycosyl transferase, family 2 EGX95_00305 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) EGX95_00380 ENOG4108IBT Inherit from COG: transposase EGX95_00405 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EGX95_00435 ENOG4105KRN Transcriptional regulator, abrb family EGX95_00480 ENOG4105K70 DNA-binding protein EGX95_00515 ENOG4105DHF Membrane EGX95_00665 ENOG4105EKQ RNA-directed DNA polymerase EGX95_00810 ENOG4105D7V transposase EGX95_00840 ENOG4107QZI cell division protein FtsK EGX95_00850 ENOG4105EKQ RNA-directed DNA polymerase EGX95_00910 ENOG4105EKQ RNA-directed DNA polymerase EGX95_00970 ENOG4105EKQ RNA-directed DNA polymerase EGX95_01130 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) EGX95_01175 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EGX95_01265 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX95_01280 ENOG4108W2Y isochorismatase EGX95_01295 ENOG4108NHD germination protein EGX95_01340 ENOG4105D9M gamma-glutamylcysteine synthetase EGX95_01350 ENOG4105C4W S-formylglutathione hydrolase EGX95_01360 ENOG4105KVH Transcriptional regulator EGX95_01405 ENOG4105E1K spore germination protein EGX95_01410 ENOG4108B31 Spore germination protein EGX95_01460 ENOG4108IMY Transcriptional regulator EGX95_01485 ENOG4105WXW Antirepressor EGX95_01505 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) EGX95_01560 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) EGX95_01650 ENOG4108TFU terminase (Small subunit) EGX95_01860 ENOG4108RDQ ABC transporter EGX95_01915 ENOG4108RDQ ABC transporter EGX95_02035 ENOG4105K4H Nlp p60 protein EGX95_02230 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) EGX95_02255 ENOG4105VZ8 Transcriptional regulator EGX95_02260 ENOG4107D63 EGX95_02275 ENOG4105DUX Transporter EGX95_02295 ENOG4105C85 amino acid EGX95_02300 ENOG4105C7N Xanthine uracil vitamin C permease EGX95_02315 ENOG4105MA6 gCN5-related N-acetyltransferase EGX95_02340 ENOG4105BZ9 Cytochrome C oxidase, subunit I EGX95_02345 ENOG4105E2S oxidase) subunit II EGX95_02365 ENOG4106CAD Protein of unknown function (DUF3311) EGX95_02370 ENOG4105E1V na solute symporter EGX95_02390 ENOG4105CE1 Ferrous iron transport protein b EGX95_02395 ENOG4105CE1 Ferrous iron transport protein b EGX95_02400 ENOG4105CE1 Ferrous iron transport protein b EGX95_02405 ENOG4105CVA phosphate EGX95_02410 ENOG4105C8U phosphate abc transporter EGX95_02415 ENOG4105E2Z phosphate ABC transporter (Permease EGX95_02540 ENOG41080XQ Signal transduction protein with cbs domains EGX95_02560 ENOG4105ETU transcriptional activator (TenA EGX95_02570 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EGX95_02580 ENOG4108VEU Thiamine monophosphate synthase EGX95_02585 ENOG41080HI glycine oxidase EGX95_02600 ENOG4105D06 uba thif-type nad fad binding protein EGX95_02605 ENOG4105DWF phosphomethylpyrimidine kinase EGX95_02655 ENOG4108INS Transcriptional regulator EGX95_02680 ENOG4105C19 ABC transporter EGX95_02690 ENOG4105F5R ABC transporter EGX95_02695 ENOG4105C2J ABC transporter EGX95_02700 ENOG4108QGH periplasmic EGX95_02705 ENOG4105C7N Xanthine uracil vitamin C permease EGX95_02715 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EGX95_02735 ENOG4105C5Y PTS System EGX95_02770 ENOG4108B31 Spore germination protein EGX95_02790 ENOG4107Y03 Nitroreductase EGX95_02795 ENOG4105ED1 spovr family EGX95_02820 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase EGX95_02825 ENOG4105XTG Pfam:DUF156 EGX95_02830 ENOG4105VFE sira family EGX95_02835 ENOG4107TPS domain protein EGX95_02840 ENOG4105VFE sira family EGX95_02845 ENOG4105VFE sira family EGX95_02855 ENOG4105VFE sira family EGX95_02865 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase EGX95_02870 ENOG41087NI Sulfite exporter TauE/SafE EGX95_02880 ENOG4108KGH TRANSCRIPTIONal EGX95_02905 ENOG4105EMD TRANSCRIPTIONal EGX95_02910 ENOG4105VCP PTS System EGX95_02915 ENOG4105VZJ PTS System EGX95_02940 ENOG41069ER domain protein EGX95_02945 ENOG4107RBB ABC transporter, permease EGX95_02950 ENOG4105C19 ABC transporter EGX95_02980 ENOG4105WEF catalase EGX95_03015 ENOG4107T5V SNARE associated Golgi EGX95_03045 ENOG4105CUB amino acid EGX95_03050 ENOG4107RWR Sodium hydrogen exchanger EGX95_03060 ENOG4106KNT transcriptional regulator EGX95_03100 ENOG4108YXU transcriptional regulator AsnC family EGX95_03110 ENOG4105KPY Small multidrug resistance protein EGX95_03115 ENOG4105KPY Small multidrug resistance protein EGX95_03135 ENOG41082F9 transcriptional regulator EGX95_03140 ENOG41061H0 Monooxygenase EGX95_03145 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX95_03165 ENOG4106A3M Cytochrome p-450 EGX95_03190 ENOG4105EWC Purine nucleoside phosphorylase EGX95_03200 ENOG4105K8R UPF0145 protein EGX95_03215 ENOG4105EKQ RNA-directed DNA polymerase EGX95_03235 ENOG4105NF4 modulator of drug activity EGX95_03240 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) EGX95_03245 ENOG4105E5W Transporter EGX95_03255 ENOG4107RKG DJ-1/PfpI family EGX95_03265 ENOG4105D5Q Arginine ornithine antiporter EGX95_03270 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EGX95_03275 ENOG4105C26 Dehydrogenase EGX95_03290 ENOG4105BZ1 (ABC) transporter EGX95_03295 ENOG4105BZ1 (ABC) transporter EGX95_03310 ENOG4105DRP amino acid AbC transporter EGX95_03315 ENOG4105CDA abc transporter atp-binding protein EGX95_03330 ENOG410839P EGX95_03365 ENOG4107FQX Alpha-acetolactate decarboxylase EGX95_03380 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase EGX95_03385 ENOG4105D4P Coproporphyrinogen iii oxidase EGX95_03405 ENOG4105CHH sulfate transporter EGX95_03440 ENOG4106AKK s-layer domain-containing protein EGX95_03450 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein EGX95_03455 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein EGX95_03470 ENOG4105CGU Enoyl-CoA hydratase EGX95_03505 ENOG4105DER m42 family EGX95_03565 ENOG4105CSH Transporter EGX95_03575 ENOG4108MRH transcriptional regulatory protein EGX95_03675 ENOG4105CDU Replicative dna helicase EGX95_03695 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX95_03770 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase EGX95_03785 ENOG4105CMT Dihydroxyacetone kinase EGX95_03800 ENOG4105CMT Dihydroxyacetone kinase EGX95_03825 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase EGX95_03925 ENOG4105WN5 stage II sporulation protein EGX95_03935 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX95_03945 ENOG4108MJI response regulator EGX95_03950 ENOG4105BZU Histidine kinase EGX95_03955 ENOG4105BZU Histidine kinase EGX95_03975 ENOG4105K8R UPF0145 protein EGX95_04015 ENOG4107VRP DNA repair exonuclease EGX95_04020 ENOG4106D4I domain protein EGX95_04030 ENOG4108IND Tetr family transcriptional regulator EGX95_04035 ENOG4105EQ0 Major Facilitator superfamily EGX95_04055 ENOG4108MUZ hydrolase EGX95_04085 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator EGX95_04100 ENOG4105C6V Glycerol-3-phosphate dehydrogenase EGX95_04110 ENOG4105EMN RNA polymerase sigma factor EGX95_04120 ENOG4105CNI cell division protein FtsW EGX95_04130 ENOG4105EEM helicase EGX95_04135 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EGX95_04160 ENOG4105K59 histidine triad (HIT) protein EGX95_04190 ENOG410905X membrane-flanked domain protein EGX95_04195 ENOG4105CKV Membrane EGX95_04225 ENOG410905X membrane-flanked domain protein EGX95_04230 ENOG4105CKV Membrane EGX95_04235 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation EGX95_04240 ENOG4105BZ4 penicillin-binding protein EGX95_04250 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) EGX95_04255 ENOG4105C1Q protoporphyrinogen oxidase EGX95_04285 ENOG4105ECB domain protein EGX95_04315 ENOG4105D29 Helix-turn-helix type 11 domain protein EGX95_04330 ENOG4106AXD EGX95_04335 ENOG4108RQ5 Beta-lactamase domain-containing protein EGX95_04340 ENOG4105DF9 Lipoate-protein, ligase EGX95_04350 ENOG4105CEY Amp-dependent synthetase and ligase EGX95_04365 ENOG4105CNA YD repeat protein EGX95_04430 ENOG4105ENX hydrolase EGX95_04435 ENOG4107RN3 metallophosphoesterase EGX95_04445 ENOG4107TVP HD domain protein EGX95_04455 ENOG4108AEY RNA polymerase sigma factor EGX95_04465 ENOG41086D8 Transcriptional regulator EGX95_04480 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EGX95_04505 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 EGX95_04525 ENOG4105ZU5 s-layer protein EGX95_04530 ENOG4107QP3 malate synthase g EGX95_04550 ENOG4105VEQ Cold shock protein EGX95_04565 ENOG4105XVF Competence transcription factor EGX95_04635 ENOG4105ERH Fumarylacetoacetate hydrolase EGX95_04660 ENOG4105CAQ asparagine synthetase EGX95_04670 ENOG4105CH6 catalase EGX95_04675 ENOG4105BZU Histidine kinase EGX95_04705 ENOG4105QNR S1 RNA binding domain protein EGX95_04710 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EGX95_04720 ENOG4107AYK membrAne EGX95_04725 ENOG41073B9 EGX95_04735 ENOG4108KP7 hydrolase EGX95_04770 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) EGX95_04775 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EGX95_04790 ENOG4105C31 Tryptophanyl-tRNA synthetase EGX95_04810 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EGX95_04815 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EGX95_04825 ENOG4108JQ7 (ABC) transporter EGX95_04830 ENOG4105UQX Mate efflux family protein EGX95_04850 ENOG4108ZCF integral membrane protein EGX95_04860 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) EGX95_04870 ENOG4105DPN Oligoendopeptidase f EGX95_04880 ENOG4108Z18 K06886 hemoglobin EGX95_04885 ENOG4105MIX Adenylate cyclase EGX95_04890 ENOG4106EFP UPF0738 protein EGX95_04905 ENOG4105EMS pseudouridine synthase EGX95_04925 ENOG4105K64 Glycosyl transferase, family 2 EGX95_04945 ENOG4107TVC Glycosyl transferase, family 2 EGX95_04965 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) EGX95_04970 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase EGX95_04980 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase EGX95_05055 ENOG4105CK7 Sodium proline symporter EGX95_05065 ENOG4105CRQ synthase (Component I) EGX95_05070 ENOG4105DDQ anthranilate synthase EGX95_05185 ENOG4105C7S Dehydrogenase EGX95_05195 ENOG4105VZ8 Transcriptional regulator EGX95_05250 ENOG4105DZ1 carboxypeptidase EGX95_05255 ENOG4105VFR signal peptidase EGX95_05290 ENOG4105C26 Dehydrogenase EGX95_05300 ENOG4105F38 ABC transporter, permease EGX95_05305 ENOG4105D38 putrescine abc transporter EGX95_05310 ENOG4107RUE extracellular solute-binding protein family 1 EGX95_05320 ENOG4105EYF MMPL domain protein EGX95_05330 ENOG4108YBP pseudouridine synthase EGX95_05340 ENOG4105K4I Scp-like extracellular EGX95_05345 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) EGX95_05350 ENOG4105CQB FAD linked oxidase domain protein EGX95_05365 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX95_05370 ENOG4105BZU Histidine kinase EGX95_05375 ENOG4105JXH GntR family transcriptional regulator EGX95_05395 ENOG4106A3R peptidase EGX95_05405 ENOG4108QTI )-transporter EGX95_05410 ENOG4107TS3 membrane protein, TerC EGX95_05415 ENOG4105CZN Potassium uptake protein EGX95_05420 ENOG410681C small acid-soluble spore protein EGX95_05425 ENOG4108Z7G MaoC domain protein dehydratase EGX95_05445 ENOG4105CHR reductase EGX95_05475 ENOG4105C4Y ABC transporter EGX95_05480 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EGX95_05505 ENOG4105E98 transcriptional regulator DeoR family EGX95_05515 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) EGX95_05525 ENOG4105PXI polysaccharide deacetylase EGX95_05535 ENOG4105BZU Histidine kinase EGX95_05540 ENOG41090MY MarR family Transcriptional regulator EGX95_05550 ENOG4106DF1 EGX95_05560 ENOG4105BZU Histidine kinase EGX95_05570 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase EGX95_05575 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) EGX95_05620 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) EGX95_05645 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EGX95_05650 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family EGX95_05655 ENOG4105CZV ABC transporter EGX95_05665 ENOG4105CJ1 ABC, transporter EGX95_05705 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A EGX95_05710 ENOG4105EA8 2-Nitropropane dioxygenase EGX95_05715 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD EGX95_05725 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein EGX95_05745 ENOG4105NQC Flavodoxin EGX95_05770 ENOG4107QMU Mate efflux family protein EGX95_05805 ENOG4105CZN Potassium uptake protein EGX95_05810 ENOG41063Y9 EGX95_05815 ENOG4105KBJ sporulation protein ytfj EGX95_05835 ENOG4105CM2 brancheD-chain amino acid aminotransferase EGX95_05840 ENOG4105C7K acetolactate synthase EGX95_05845 ENOG4108ZP8 Acetolactate synthase small subunit EGX95_05920 ENOG4107RVV histidinol phosphate phosphatase, hisj family EGX95_05935 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase EGX95_05940 ENOG4105E0M Sulfatase EGX95_05950 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) EGX95_05970 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) EGX95_05975 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) EGX95_05985 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EGX95_05990 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein EGX95_05995 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein EGX95_06000 ENOG4105C8J )-transporter EGX95_06020 ENOG4105DFD Na H antiporter EGX95_06040 ENOG4105ENE Histidine kinase EGX95_06045 ENOG4105WH1 Two component transcriptional regulator luxr family EGX95_06065 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) EGX95_06110 ENOG4105CJ3 phosphate transporter EGX95_06115 ENOG4107GRR phosphate transport regulator EGX95_06120 ENOG4105BZ4 penicillin-binding protein EGX95_06135 ENOG4105BZU Histidine kinase EGX95_06140 ENOG4105I3N Conserved Protein EGX95_06155 ENOG4105BZU Histidine kinase EGX95_06185 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EGX95_06190 ENOG4105DZ1 carboxypeptidase EGX95_06195 ENOG4108JIC nucleoside recognition domain protein EGX95_06205 ENOG4105FE9 pseudouridine synthase EGX95_06215 ENOG4107TWT Cytochrome c biogenesis protein EGX95_06220 ENOG4105CRE cytochrome C EGX95_06225 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX95_06230 ENOG4105BZU Histidine kinase EGX95_06235 ENOG4108WBT adenosyltransferase EGX95_06240 ENOG41063SB peptidase EGX95_06250 ENOG4108SAX Membrane EGX95_06265 ENOG4105C9U ATP-dependent DNA helicase RecQ EGX95_06270 ENOG4105I7S Abortive infection protein EGX95_06280 ENOG4107RGJ metallophosphoesterase EGX95_06285 ENOG4107X2D transcriptional regulator, merr family EGX95_06290 ENOG4108S6Z Negative regulator of genetic competence EGX95_06315 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase EGX95_06320 ENOG4105HDK L-asparaginase EGX95_06350 ENOG4105S2F EGX95_06355 ENOG41065D1 EGX95_06385 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) EGX95_06400 ENOG4105XXQ heptaprenyl diphosphate synthase component I EGX95_06410 ENOG4105EAH synthase EGX95_06430 ENOG4105CIH Imidazole acetol-phosphate transaminase EGX95_06440 ENOG41068YB TPR repeat-containing protein EGX95_06455 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) EGX95_06460 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) EGX95_06500 ENOG4108JYZ YitT family EGX95_06505 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase EGX95_06520 ENOG4105FJR Lmbe family EGX95_06525 ENOG4105CPK Glycosyl transferase (Group 1 EGX95_06560 ENOG4105DVT helicase EGX95_06565 ENOG4105YAC EGX95_06585 ENOG4105CSM endonuclease III EGX95_06595 ENOG4105BZ4 penicillin-binding protein EGX95_06650 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) EGX95_06660 ENOG4105DVT helicase EGX95_06665 ENOG4105CTD carboxy-peptidase EGX95_06675 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EGX95_06685 ENOG4105C2W permease EGX95_06690 ENOG4105DHF Membrane EGX95_06695 ENOG410890F Dynamin family EGX95_06705 ENOG4108W0I acetyltransferase EGX95_06715 ENOG4105KHC sulfurtransferase EGX95_06740 ENOG4106032 Glutathionylspermidine synthase EGX95_06795 ENOG41081VK Ribonuclease EGX95_06860 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EGX95_06870 ENOG4107RWR Sodium hydrogen exchanger EGX95_06875 ENOG4105CN5 Metallo-Beta-Lactamase EGX95_06880 ENOG4108Z5V transcriptional regulator, merr family EGX95_06895 ENOG4105H67 Protein of unknown function (DUF421) EGX95_06900 ENOG41080C8 DUF218 domain EGX95_06935 ENOG4107Y80 Major Facilitator superfamily EGX95_06965 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) EGX95_06975 ENOG4107R0U MotA TolQ exbB proton channel EGX95_06980 ENOG4105ER2 Ompa motb domain protein EGX95_06985 ENOG4107YTP response regulator receiver protein EGX95_06990 ENOG4105CBS Chea signal transduction histidine kinase EGX95_06995 ENOG4105DD5 Flagellar motor switch protein EGX95_07010 ENOG4105BZU Histidine kinase EGX95_07030 ENOG4105E1Q flagellar hook-associated protein EGX95_07035 ENOG4105DTJ flagellar hook-associated protein EGX95_07040 ENOG4107TPX flagellar hook-associated EGX95_07055 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) EGX95_07060 ENOG4108ZC9 flagellar basal-body rod protein flgc EGX95_07065 ENOG41075Z6 flagellar hook-basal body complex protein fliE EGX95_07070 ENOG4107U2N Flagellar M-ring protein EGX95_07075 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) EGX95_07105 ENOG4105BZE flagellar hook protein, FlgE EGX95_07120 ENOG4107R88 Chemotaxis protein (CheV) EGX95_07135 ENOG4105I03 Flagellin EGX95_07140 ENOG4105I03 Flagellin EGX95_07145 ENOG4105E4C Lytic transglycosylase catalytic EGX95_07155 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) EGX95_07160 ENOG4105DD5 Flagellar motor switch protein EGX95_07170 ENOG4105CN7 Flagellar biosynthetic protein FliP EGX95_07175 ENOG4105VS8 Flagellar biosynthetic protein fliq EGX95_07185 ENOG4105D00 flagellar biosynthetic protein flhB EGX95_07190 ENOG4105D7B Flagellar biosynthesis protein flha EGX95_07195 ENOG4105FZW flagellar biosynthesis regulator FlhF EGX95_07200 ENOG4105KTQ flagellar basal-body rod protein EGX95_07205 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) EGX95_07240 ENOG4105KAC Antibiotic biosynthesis monooxygenase EGX95_07260 ENOG4108U4N (sortase) family EGX95_07285 ENOG4105DUM transcriptional regulator, lysR family EGX95_07290 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EGX95_07300 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component EGX95_07305 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) EGX95_07320 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr EGX95_07345 ENOG4105CVJ phosphoglycerate mutase EGX95_07365 ENOG4105K56 Transcriptional regulator EGX95_07375 ENOG4105CAQ asparagine synthetase EGX95_07395 ENOG4105PGM cation diffusion facilitator family transporter EGX95_07405 ENOG4105DRR Transcriptional regulator, GntR family EGX95_07410 ENOG4108UZ3 Transporter EGX95_07420 ENOG4105DFD Na H antiporter EGX95_07430 ENOG4105C9Q fumarate hydratase class II EGX95_07450 ENOG4107QJQ Mate efflux family protein EGX95_07455 ENOG4105EC3 peptidase S51, dipeptidase E EGX95_07495 ENOG4106BRA Membrane EGX95_07535 ENOG4105CJ1 ABC, transporter EGX95_07555 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) EGX95_07565 ENOG4108IJ0 Aspartate ammonia-lyase EGX95_07570 ENOG4105C6K Malic enzyme EGX95_07640 ENOG4105FVX EGX95_07695 ENOG4105CSR polyphosphate kinase 2 EGX95_07700 ENOG4105U3E Transcriptional regulator EGX95_07710 ENOG4105DXI Major Facilitator superfamily EGX95_07725 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EGX95_07735 ENOG4105EU0 Major facilitator Superfamily EGX95_07740 ENOG4105C6T cysteine synthase EGX95_07760 ENOG4105C8J )-transporter EGX95_07770 ENOG4105X5K response regulator receiver protein EGX95_07775 ENOG4105H67 Protein of unknown function (DUF421) EGX95_07790 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) EGX95_07795 ENOG4105CM2 brancheD-chain amino acid aminotransferase EGX95_07800 ENOG4105C7K acetolactate synthase EGX95_07805 ENOG4108ZP8 Acetolactate synthase small subunit EGX95_07810 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase EGX95_07820 ENOG4105C7B Threonine dehydratase EGX95_07845 ENOG4105C6X Major Facilitator EGX95_07850 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b EGX95_07860 ENOG4105DY9 regulatoR EGX95_07865 ENOG4105CYC Transferase EGX95_07885 ENOG4105F6J Alpha beta hydrolase fold EGX95_07895 ENOG41068WN EGX95_07900 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EGX95_07915 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) EGX95_07930 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) EGX95_07935 ENOG4105C0X amino acid EGX95_07965 ENOG4107RHR regulatoR EGX95_07975 ENOG4105D9N nucleoside EGX95_07980 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) EGX95_08000 ENOG4107RAQ aminopeptidase EGX95_08050 ENOG4108T5E Copper resistance protein EGX95_08055 ENOG4105KTB nuclear export factor GLE1 EGX95_08060 ENOG4107RT3 EamA-like transporter family EGX95_08065 ENOG4105GZI Transcriptional regulator EGX95_08070 ENOG4108Z40 Transcriptional regulator EGX95_08075 ENOG4107ZXU DSBA oxidoreductase EGX95_08080 ENOG4108TVJ Nitroreductase EGX95_08085 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) EGX95_08090 ENOG4106F5Q Membrane EGX95_08095 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) EGX95_08105 ENOG4105CKI cobalamin synthesis protein EGX95_08115 ENOG4105C0Z ABC transporter EGX95_08120 ENOG4108IV0 ABC, transporter EGX95_08125 ENOG4105C32 Amino acid ABC transporter (Permease) EGX95_08135 ENOG4105SKE transcriptional Regulator LysR family EGX95_08145 ENOG4105MDS 4-oxalocrotonate tautomerase EGX95_08165 ENOG4105C4M (Ubiquinol oxidase) subunit I EGX95_08170 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EGX95_08175 ENOG4108JJ9 ABC, transporter EGX95_08180 ENOG4108JJ8 (ABC) transporter EGX95_08190 ENOG4105K64 Glycosyl transferase, family 2 EGX95_08200 ENOG4108UT6 Transferase hexapeptide repeat containing protein EGX95_08225 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A EGX95_08255 ENOG4105BZ1 (ABC) transporter EGX95_08260 ENOG4105EFI regulatoR EGX95_08265 ENOG4105BZU Histidine kinase EGX95_08285 ENOG41075D4 Aminoglycoside 6-adenylyltransferase EGX95_08290 ENOG4108ZJ4 polysaccharide deacetylase EGX95_08315 ENOG4105D6E homoserine dehydrogenase EGX95_08340 ENOG4108KGH TRANSCRIPTIONal EGX95_08345 ENOG4105BZU Histidine kinase EGX95_08350 ENOG4107VMI polysaccharide deacetylase EGX95_08360 ENOG4105KT7 mgtC SapB transporter EGX95_08365 ENOG4105VRR gCN5-related N-acetyltransferase EGX95_08370 ENOG4105YWU small acid-soluble spore protein EGX95_08380 ENOG4108ZUB Lysine exporter protein (Lyse ygga) EGX95_08385 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EGX95_08435 ENOG4105KRN Transcriptional regulator, abrb family EGX95_08455 ENOG4108KB1 transcriptional regulator, arac family EGX95_08465 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component EGX95_08470 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component EGX95_08475 ENOG4105CT8 Phosphorylase EGX95_08480 ENOG4105DKQ ROK family EGX95_08485 ENOG4105E70 isomerase EGX95_08490 ENOG4105CE4 GlcNAc 6-P deacetylase EGX95_08495 ENOG4105DE4 1-phosphofructokinase EGX95_08500 ENOG4105D2M Aldolase EGX95_08505 ENOG4105ESP cell wall surface anchor family protein EGX95_08510 ENOG4105ESP cell wall surface anchor family protein EGX95_08515 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase EGX95_08520 ENOG4105YVS arsR family transcriptional regulator EGX95_08525 ENOG4105CPC Aldo Keto reductase EGX95_08530 ENOG4107XZQ multidrug resistance protein EGX95_08555 ENOG4105C8Q Methyl-accepting chemotaxis EGX95_08570 ENOG4108K88 Membrane EGX95_08575 ENOG4108WPJ Ferritin-like domain EGX95_08590 ENOG4105DEN Luciferase family EGX95_08605 ENOG4105VMI -acetyltransferase EGX95_08610 ENOG4107QM2 Aldo Keto reductase EGX95_08615 ENOG4105CKI cobalamin synthesis protein EGX95_08625 ENOG4105DSE periplasmic solute binding protein EGX95_08630 ENOG4105K4T epimerase EGX95_08640 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EGX95_08665 ENOG4105CVJ phosphoglycerate mutase EGX95_08685 ENOG4107T5V SNARE associated Golgi EGX95_08700 ENOG4108PJD permease EGX95_08710 ENOG4108S4H thioesterase Superfamily protein EGX95_08720 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) EGX95_08740 ENOG4105SXS Protein of unknown function (DUF456) EGX95_08745 ENOG4105C37 (CBS) domain EGX95_08765 ENOG4108Z7R Chaperone CsaA EGX95_08785 ENOG4108ZRV stage ii sporulation protein p EGX95_08795 ENOG4108VXD carboxy-peptidase EGX95_08805 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) EGX95_08830 ENOG4108X4Q Hydrolase EGX95_08840 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EGX95_08845 ENOG4107RBS Methyltransferase EGX95_08860 ENOG41087PP glycosyltransferase MGT family EGX95_08865 ENOG4108JYZ YitT family EGX95_08870 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EGX95_08900 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) EGX95_08925 ENOG4105KBJ sporulation protein ytfj EGX95_08950 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) EGX95_08970 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EGX95_08975 ENOG4105VTR Integrase EGX95_08985 ENOG41067QW Transcriptional regulator EGX95_09030 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX95_09050 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) EGX95_09090 ENOG410682Q Phage transcriptional regulator, ArpU EGX95_09125 ENOG4105CAR Terminase, large subunit EGX95_09215 ENOG4105XSJ toxin secretion phage lysis holin EGX95_09270 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein EGX95_09275 ENOG4105EMN RNA polymerase sigma factor EGX95_09290 ENOG4105CNW domain protein EGX95_09300 ENOG4108V06 Glutathione peroxidase EGX95_09315 ENOG4105C7R Atpase associated with various cellular activities aaa_3 EGX95_09325 ENOG4108IUE nitrate reductase beta subunit EGX95_09330 ENOG4105R3A Nitrate reductase EGX95_09340 ENOG4107V6Q Cyclic nucleotide-binding domain EGX95_09345 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EGX95_09350 ENOG4105D06 uba thif-type nad fad binding protein EGX95_09355 ENOG4105CVM Molybdenum cofactor synthesis domain protein EGX95_09360 ENOG4108ZAF Molybdopterin EGX95_09390 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein EGX95_09395 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein EGX95_09400 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EGX95_09405 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit EGX95_09410 ENOG4108IFG nitrite reductase, (NAD(P)H) EGX95_09415 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) EGX95_09450 ENOG4105MCT stage V sporulation protein S EGX95_09475 ENOG4105C5H ABC transporter EGX95_09490 ENOG4108UUM single-stranded DNA-binding protein EGX95_09520 ENOG4107YX5 Pfam:DUF548 EGX95_09570 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) EGX95_09580 ENOG4105C5S asparaginyl-tRNA synthetase EGX95_09585 ENOG4105C8J )-transporter EGX95_09605 ENOG4107XGZ Hydrolase EGX95_09610 ENOG4105CY2 Citrate transporter EGX95_09615 ENOG4105C0A alcohol dehydrogenase EGX95_09630 ENOG4105KD7 acetyltransferase EGX95_09635 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase EGX95_09660 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 EGX95_09675 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) EGX95_09695 ENOG4107RVG penicillin-binding protein EGX95_09700 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) EGX95_09705 ENOG4105E9Q Acyl-transferase EGX95_09710 ENOG4108UT2 hemolysin iii EGX95_09720 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) EGX95_09730 ENOG4108RCR degv family EGX95_09735 ENOG4105E8R UPF0173 metal-dependent hydrolase EGX95_09740 ENOG4108KF3 Electron transport protein SCO1 SenC EGX95_09745 ENOG4107Y70 Heat shock protein EGX95_09750 ENOG4105CAQ asparagine synthetase EGX95_09770 ENOG4108MES Periplasmic binding protein EGX95_09775 ENOG4105F0I Aminotransferase EGX95_09805 ENOG4105D8X mechanosensitive ion channel EGX95_09810 ENOG4105BZU Histidine kinase EGX95_09815 ENOG4105WH1 Two component transcriptional regulator luxr family EGX95_09825 ENOG4106KNT transcriptional regulator EGX95_09885 ENOG4108IJ8 ABC transporter EGX95_09890 ENOG4105E90 ABC transporter EGX95_09925 ENOG4105C37 (CBS) domain EGX95_09950 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EGX95_09965 ENOG4107S4Y M20 DapE family protein YgeY EGX95_09970 ENOG4108TSC N-acetyltransferase EGX95_09975 ENOG4108JUB Transcriptional regulator EGX95_09980 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein EGX95_10020 ENOG4108N23 SpoOM-related protein EGX95_10025 ENOG410841Q phosphoesterase PA-phosphatase related protein EGX95_10035 ENOG4105SZ6 Thioredoxin EGX95_10045 ENOG4108TFU terminase (Small subunit) EGX95_10080 ENOG4108AEY RNA polymerase sigma factor EGX95_10115 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EGX95_10160 ENOG4105BZ4 penicillin-binding protein EGX95_10170 ENOG4105CZM Major Facilitator EGX95_10175 ENOG4105W8X HesB YadR YfhF-family protein EGX95_10185 ENOG4105DXD 2-methylcitrate dehydratase EGX95_10190 ENOG4105CR4 methylisocitrate lyase EGX95_10195 ENOG4105C1G acyl-Coa dehydrogenase EGX95_10200 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EGX95_10210 ENOG4105N14 lysine exporter protein LysE YggA EGX95_10215 ENOG4105E39 Enoyl-CoA hydratase EGX95_10230 ENOG4107RFY SbcCD D subunit EGX95_10255 ENOG4105FCD Major Facilitator EGX95_10260 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase EGX95_10265 ENOG4105E4F Isochorismate synthase EGX95_10270 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase EGX95_10275 ENOG4105WQI isochorismatase EGX95_10280 ENOG4105CEY Amp-dependent synthetase and ligase EGX95_10290 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX95_10305 ENOG4105K70 DNA-binding protein EGX95_10325 ENOG4105BZG amino acid carrier protein EGX95_10355 ENOG4105FE9 pseudouridine synthase EGX95_10360 ENOG4105C22 threonyL-tRNA synthetase EGX95_10365 ENOG4105C19 ABC transporter EGX95_10400 ENOG4108D32 Methyltransferase EGX95_10410 ENOG4105EKQ RNA-directed DNA polymerase EGX95_10435 ENOG41081I9 integral membrane protein EGX95_10460 ENOG4105EYF MMPL domain protein EGX95_10480 ENOG4105WCN acetyltransferase EGX95_10520 ENOG4105C1Q protoporphyrinogen oxidase EGX95_10530 ENOG41068WN EGX95_10540 ENOG4105VEQ Cold shock protein EGX95_10560 ENOG410667J hydrolase EGX95_10580 ENOG4107V2S Transcriptional regulator EGX95_10585 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) EGX95_10600 ENOG4105DND Transcriptional regulator EGX95_10605 ENOG4108RPX mosc domain containing protein EGX95_10620 ENOG4105BZ1 (ABC) transporter EGX95_10625 ENOG4105BZ1 (ABC) transporter EGX95_10640 ENOG4108JCI Transcriptional regulator EGX95_10685 ENOG4108KPJ rna polymerase sigma factor EGX95_10705 ENOG4105F32 YngK protein EGX95_10730 ENOG4105RD7 BadF BadG BcrA BcrD EGX95_10740 ENOG4107STF Involved in phosphonate degradation (By similarity) EGX95_10765 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) EGX95_10780 ENOG4105C1J atp-dependent rna helicase EGX95_10800 ENOG4108RZE Tetr family transcriptional regulator EGX95_10820 ENOG41088CC tellurite resistance protein tehB EGX95_10830 ENOG4107RA9 decarboxylase EGX95_10855 ENOG4105CIN aminoacyl-histidine dipeptidase EGX95_10880 ENOG4107RF6 penicillin-binding protein EGX95_10885 ENOG4107RF6 penicillin-binding protein EGX95_10895 ENOG4105DIN metallophosphoesterase EGX95_10905 ENOG4105CJ1 ABC, transporter EGX95_10915 ENOG4107Z3H Transcriptional regulator, TetR family EGX95_10930 ENOG4105C1G acyl-Coa dehydrogenase EGX95_10935 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EGX95_10940 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit EGX95_10945 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase EGX95_10950 ENOG4105E39 Enoyl-CoA hydratase EGX95_10955 ENOG4107QX3 carboxylase EGX95_10960 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EGX95_10975 ENOG4105DBI uridine monophosphokinase EGX95_11000 ENOG4105T9C HD domain EGX95_11010 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) EGX95_11055 ENOG4105FQP Beta-lactamase EGX95_11065 ENOG4107Y80 Major Facilitator superfamily EGX95_11075 ENOG41089UC methyltransferase, type 11 EGX95_11120 ENOG4105CPQ Dehydrogenase EGX95_11125 ENOG410900G Protein of unknown function (DUF421) EGX95_11130 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) EGX95_11145 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein EGX95_11155 ENOG4105DK7 lysyl-tRNA synthetase EGX95_11220 ENOG4105D6E homoserine dehydrogenase EGX95_11235 ENOG4105ETU transcriptional activator (TenA EGX95_11345 ENOG4107EV6 Inherit from COG: YD repeat protein EGX95_11420 ENOG410667J hydrolase EGX95_11425 ENOG4105BZU Histidine kinase EGX95_11430 ENOG4107RF6 penicillin-binding protein EGX95_11465 ENOG4108HGU Histidine kinase EGX95_11475 ENOG4105RHY Pfam:UPF0157 EGX95_11480 ENOG4105CB2 alcohol dehydrogenase EGX95_11485 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase EGX95_11490 ENOG4105CJN penicillin-binding protein EGX95_11495 ENOG4108IG5 Transcriptional regulator EGX95_11500 ENOG4105CHR reductase EGX95_11560 ENOG4107VXM glycerophosphoryl diester phosphodiesterase EGX95_11585 ENOG4107Y9U Membrane EGX95_11595 ENOG4105EGD dinuclear metal center protein, YbgI family EGX95_11615 ENOG4105FCD Major Facilitator EGX95_11630 ENOG4105E09 nadh pyrophosphatase EGX95_11635 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EGX95_11640 ENOG4108Z4K mutator MutT protein EGX95_11670 ENOG4108XI2 Domain of unknown function (DUF1963) EGX95_11695 ENOG4108NRW Phospholipase, patatin family EGX95_11700 ENOG4105KWG Pfam:DUF1696 EGX95_11735 ENOG4105PKS Excinuclease abc c subunit domain protein EGX95_11770 ENOG4107VFR oxidoreductase EGX95_11795 ENOG4105U0R haloacid dehalogenase-like hydrolase EGX95_11815 ENOG4108IUM Glycogen debranching enzyme EGX95_11830 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) EGX95_11835 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EGX95_11890 ENOG4105MSI germination protein ypeb EGX95_11930 ENOG4107Z3H Transcriptional regulator, TetR family EGX95_11965 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family EGX95_11980 ENOG4105E98 transcriptional regulator DeoR family EGX95_12000 ENOG4107QKR Dehydrogenase EGX95_12010 ENOG4107RUY (E1 component), alpha subunit EGX95_12020 ENOG4105E1F short-chain dehydrogenase reductase EGX95_12025 ENOG4105RHY Pfam:UPF0157 EGX95_12030 ENOG4105DBI uridine monophosphokinase EGX95_12065 ENOG4107SQ8 Glycine betaine EGX95_12070 ENOG4108IJ7 Glycine betaine EGX95_12095 ENOG4105E66 phosphoriboisomerase A EGX95_12100 ENOG41082BV acetyltransferase EGX95_12105 ENOG4108M1A Chitin-binding protein EGX95_12110 ENOG41087PP glycosyltransferase MGT family EGX95_12130 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EGX95_12135 ENOG4105MSB protein, conserved in bacteria EGX95_12145 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 EGX95_12165 ENOG4108Z7F N-acetyltransferase EGX95_12185 ENOG4105EEM helicase EGX95_12205 ENOG4105C9U ATP-dependent DNA helicase RecQ EGX95_12255 ENOG4108M1A Chitin-binding protein EGX95_12280 ENOG4105BZG amino acid carrier protein EGX95_12285 ENOG4105C26 Dehydrogenase EGX95_12290 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EGX95_12295 ENOG4105CTU Proline racemase EGX95_12300 ENOG4105CTU Proline racemase EGX95_12305 ENOG41080HI glycine oxidase EGX95_12315 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein EGX95_12345 ENOG4107T5V SNARE associated Golgi EGX95_12350 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD EGX95_12355 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EGX95_12370 ENOG4105DTQ mandelate racemase muconate lactonizing EGX95_12420 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) EGX95_12425 ENOG4105BZU Histidine kinase EGX95_12430 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX95_12450 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 EGX95_12465 ENOG4105DPN Oligoendopeptidase f EGX95_12475 ENOG4105EPR degv family EGX95_12735 ENOG4105KRN Transcriptional regulator, abrb family EGX95_12805 ENOG4105C2M dna polymerase I EGX95_12915 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) EGX95_12920 ENOG4106K7D Major facilitator family transporter EGX95_12945 ENOG4107BMA Transglycosylase associated protein EGX95_12960 ENOG41089UC methyltransferase, type 11 EGX95_12990 ENOG4105CHM Aminotransferase EGX95_13005 ENOG4108ZMI UPF0477 protein EGX95_13060 ENOG4105C02 permease EGX95_13070 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) EGX95_13075 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EGX95_13080 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein EGX95_13125 ENOG4108AQF aminoglycoside N(3)-acetyltransferase EGX95_13170 ENOG4107VC0 DNA alkylation repair enzyme EGX95_13180 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase EGX95_13190 ENOG4107VMI polysaccharide deacetylase EGX95_13195 ENOG4108ZCF integral membrane protein EGX95_13200 ENOG4105E0M Sulfatase EGX95_13210 ENOG4105C5H ABC transporter EGX95_13220 ENOG4105EYF MMPL domain protein EGX95_13230 ENOG41082JN Transcriptional regulator EGX95_13250 ENOG4105CIH Imidazole acetol-phosphate transaminase EGX95_13260 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase EGX95_13290 ENOG41069ER domain protein EGX95_13305 ENOG4105D4B ABC, transporter EGX95_13315 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane EGX95_13325 ENOG4105DKT Transcriptional regulator EGX95_13330 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) EGX95_13340 ENOG41061GT Aldolase EGX95_13350 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) EGX95_13380 ENOG4105II7 pyrroline-5-carboxylate reductase EGX95_13390 ENOG4107258 Transcriptional regulator EGX95_13405 ENOG4105E0Y RtcB Protein EGX95_13410 ENOG4105ECK Fatty Acid Desaturase EGX95_13440 ENOG4105VMP Transcriptional regulator EGX95_13455 ENOG41090T1 Membrane EGX95_13465 ENOG4108WCX response regulator EGX95_13475 ENOG4105KNA -acetyltransferase EGX95_13500 ENOG4105C7R Atpase associated with various cellular activities aaa_3 EGX95_13520 ENOG4105C8Y Acetylornithine aminotransferase EGX95_13530 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EGX95_13550 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes EGX95_13580 ENOG4105C7R Atpase associated with various cellular activities aaa_3 EGX95_13590 ENOG4108TVJ Nitroreductase EGX95_13595 ENOG4105FS7 Transcriptional regulator EGX95_13635 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family EGX95_13645 ENOG4105C19 ABC transporter EGX95_13670 ENOG4108DMH HTH_ARAC EGX95_13675 ENOG4108XET gCN5-related N-acetyltransferase EGX95_13690 ENOG4108PCN EamA-like transporter family EGX95_13735 ENOG410635A Membrane EGX95_13740 ENOG4105KNA -acetyltransferase EGX95_13745 ENOG4108IQI permease EGX95_13755 ENOG4105F1N DNA alkylation repair EGX95_13795 ENOG4107RF6 penicillin-binding protein EGX95_13835 ENOG4105P4J Allophanate hydrolase, subunit 1 EGX95_13845 ENOG4107258 Transcriptional regulator EGX95_13855 ENOG4106N3A copper homeostasis protein cutc EGX95_13860 ENOG4108ZRV stage ii sporulation protein p EGX95_13865 ENOG4108ZHR arsR family transcriptional regulator EGX95_13875 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX95_13885 ENOG4105FDT acyl-CoA dehydrogenase EGX95_13900 ENOG4105DWD nucleoside recognition domain protein EGX95_13940 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) EGX95_14005 ENOG4105E2A Dehydrogenase EGX95_14015 ENOG4108IJ0 Aspartate ammonia-lyase EGX95_14020 ENOG4105HDK L-asparaginase EGX95_14025 ENOG4108IMY Transcriptional regulator EGX95_14030 ENOG4105DQ6 Transposase EGX95_14035 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) EGX95_14040 ENOG4105CUB amino acid EGX95_14045 ENOG4105II7 pyrroline-5-carboxylate reductase EGX95_14050 ENOG4108NHD germination protein EGX95_14055 ENOG4108Q8B Spore germination protein EGX95_14080 ENOG4105CSV Glutaminase EGX95_14115 ENOG4107QJQ Mate efflux family protein EGX95_14125 ENOG4107QTZ amino acid EGX95_14130 ENOG4105CGH 5'-nucleotidase EGX95_14135 ENOG4105CH6 catalase EGX95_14190 ENOG4108606 TspO/MBR family EGX95_14195 ENOG4105CVP deoxyribo-dipyrimidine photolyase EGX95_14220 ENOG4108TWJ NADH dehydrogenase subunit 5 EGX95_14225 ENOG4105GPN Uncharacterized conserved protein (DUF2294) EGX95_14245 ENOG4105E1K spore germination protein EGX95_14260 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase EGX95_14300 ENOG4105DET Rhamnulokinase EGX95_14305 ENOG4107W7X Aldolase EGX95_14315 ENOG4105CNN ABC, transporter EGX95_14325 ENOG4105NWF RbsD or FucU transport EGX95_14330 ENOG4105ETE Transcriptional regulator (LacI family EGX95_14340 ENOG4105D6J arsenicaL-resistance protein EGX95_14345 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase EGX95_14350 ENOG41085FC arsR family transcriptional regulator EGX95_14360 ENOG4105NAE bifunctional deaminase-reductase domain protein EGX95_14380 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EGX95_14420 ENOG4107P5I polyketide synthase EGX95_14425 ENOG4108IG5 Transcriptional regulator EGX95_14430 ENOG4105F27 Major Facilitator EGX95_14435 ENOG4105M4P Tetr family transcriptional regulator EGX95_14440 ENOG4105CHR reductase EGX95_14445 ENOG4108YXU transcriptional regulator AsnC family EGX95_14475 ENOG4105N0V mono-oxygenase ydhR EGX95_14490 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) EGX95_14495 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX95_14555 ENOG4105K6H D-cysteine desulfhydrase EGX95_14585 ENOG4105W1Y Transcriptional regulator EGX95_14590 ENOG4105JQZ Methyltransferase EGX95_14610 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) EGX95_14635 ENOG4105BZU Histidine kinase EGX95_14650 ENOG4108U05 Transcriptional regulator EGX95_14655 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 EGX95_14665 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) EGX95_14695 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A EGX95_14710 ENOG4108JQ1 Dehydrogenase EGX95_14730 ENOG41082W1 Cupin 2, conserved barrel domain protein EGX95_14740 ENOG410874W AraC family transcriptional regulator EGX95_14765 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase EGX95_14805 ENOG4108ISG Major Facilitator EGX95_14820 ENOG4107MII Sugar-specific transcriptional regulator TrmB EGX95_14825 ENOG4105CZM Major Facilitator EGX95_14840 ENOG4105DA5 (ABC) transporter EGX95_14845 ENOG41069JR EGX95_14855 ENOG4105RXJ EGX95_14860 ENOG4105KPY Small multidrug resistance protein EGX95_14865 ENOG4105KBX Transcriptional regulator, TetR family EGX95_14870 ENOG4107AUC EGX95_14880 ENOG4105CRW Short chain fatty acid transporter EGX95_14890 ENOG4105DYS nad(p)h dehydrogenase (quinone) EGX95_14925 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) EGX95_14965 ENOG4107TXC Transcriptional regulator EGX95_14990 ENOG4105EKQ RNA-directed DNA polymerase EGX95_15000 ENOG4105RHY Pfam:UPF0157 EGX95_15005 ENOG4108Z66 YbaK ebsC protein EGX95_15025 ENOG4105KVH Transcriptional regulator EGX95_15030 ENOG4108RCM Nitroreductase EGX95_15050 ENOG4108PSK reductase EGX95_15060 ENOG4105CJ1 ABC, transporter EGX95_15115 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase EGX95_15120 ENOG4105DKQ ROK family EGX95_15125 ENOG4108UW5 maltose o-acetyltransferase EGX95_15130 ENOG4105C31 Tryptophanyl-tRNA synthetase EGX95_15165 ENOG4105DMQ Methyltransferase EGX95_15175 ENOG4105EV4 Multidrug resistance protein mdtH EGX95_15200 ENOG4105C37 (CBS) domain EGX95_15215 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase EGX95_15220 ENOG4105FAW cDP-glucose 4,6-dehydratase EGX95_15250 ENOG4105DDN Pentapeptide repeat-containing protein EGX95_15255 ENOG4105XDF Protein of unknown function (DUF1272) EGX95_15260 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) EGX95_15265 ENOG4105CMG Carbohydrate kinase EGX95_15270 ENOG4105C6Z Gluconate EGX95_15275 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EGX95_15290 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase EGX95_15295 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase EGX95_15300 ENOG4105CIS alcohol dehydrogenase EGX95_15305 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone EGX95_15320 ENOG4105EWI Short-chain dehydrogenase reductase Sdr EGX95_15335 ENOG4105CV8 reductase EGX95_15340 ENOG4105F27 Major Facilitator EGX95_15355 ENOG4105C44 Serine transporter EGX95_15365 ENOG4105EKQ RNA-directed DNA polymerase EGX95_15400 ENOG4105KVH Transcriptional regulator EGX95_15405 ENOG4108TZY GntR Family Transcriptional Regulator EGX95_15410 ENOG4105D9R oxidoreductase EGX95_15415 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase EGX95_15420 ENOG4105KVH Transcriptional regulator EGX95_15425 ENOG4105KVH Transcriptional regulator EGX95_15465 ENOG4105JAB phenazine biosynthesis protein, phzf family EGX95_15475 ENOG4105CHR reductase EGX95_15490 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein EGX95_15495 ENOG4105KVH Transcriptional regulator EGX95_15510 ENOG4108ZJ4 polysaccharide deacetylase EGX95_15590 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) EGX95_15630 ENOG4105H3G oxidoreductase EGX95_15675 ENOG4105K7K Transcriptional regulator EGX95_15680 ENOG4105CIS alcohol dehydrogenase EGX95_15710 ENOG4108TN2 lmbE family EGX95_15720 ENOG4107R3E Citrate transporter EGX95_15735 ENOG4108MES Periplasmic binding protein EGX95_15740 ENOG4105EHG Permease protein EGX95_15745 ENOG4105DQ5 transport system permease protein EGX95_15750 ENOG4105NX3 Membrane EGX95_15770 ENOG4107CUJ Protein of unknown function (DUF2690) EGX95_15780 ENOG4107V2S Transcriptional regulator EGX95_15800 ENOG4105C98 muts2 protein EGX95_15805 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase EGX95_15810 ENOG4105DPN Oligoendopeptidase f EGX95_15845 ENOG4107VXM glycerophosphoryl diester phosphodiesterase EGX95_15855 ENOG41082BM Transcriptional regulator, arsr family EGX95_15860 ENOG4105CIS alcohol dehydrogenase EGX95_15870 ENOG4107JM4 Tetratricopeptide repeat EGX95_15885 ENOG4105RHY Pfam:UPF0157 EGX95_15895 ENOG4105C09 Bile acid EGX95_15900 ENOG4105CQB FAD linked oxidase domain protein EGX95_15935 ENOG4105KT7 mgtC SapB transporter EGX95_15950 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase EGX95_15955 ENOG4105EAB amino acid AbC transporter EGX95_15965 ENOG4108HW4 amino acid AbC transporter EGX95_15970 ENOG41073R8 VanW family EGX95_15980 ENOG4108R1P EGX95_15995 ENOG4105VEQ Cold shock protein EGX95_16015 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) EGX95_16035 ENOG410904N short-chain dehydrogenase reductase EGX95_16045 ENOG4106IQC argininosuccinate lyase EGX95_16060 ENOG4108IA2 Sodium pantothenate symporter EGX95_16070 ENOG4105C26 Dehydrogenase EGX95_16075 ENOG4105CHR reductase EGX95_16085 ENOG4105EWU Squalene--hopene cyclase EGX95_16095 ENOG4105FR1 rard protein EGX95_16100 ENOG410696E Membrane EGX95_16115 ENOG4105D1F ATP-binding protein EGX95_16125 ENOG4108ZAF Molybdopterin EGX95_16130 ENOG4105CVM Molybdenum cofactor synthesis domain protein EGX95_16135 ENOG4105D06 uba thif-type nad fad binding protein EGX95_16140 ENOG4105TMB Formate nitrite transporter EGX95_16150 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) EGX95_16155 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) EGX95_16165 ENOG4108JB9 formate dehydrogenase EGX95_16170 ENOG4105E1K spore germination protein EGX95_16230 ENOG4107QJT sodium dicarboxylate symporter EGX95_16235 ENOG4108KGH TRANSCRIPTIONal EGX95_16245 ENOG4105EMN RNA polymerase sigma factor EGX95_16260 ENOG4105CIG ABC transporter EGX95_16270 ENOG4105D9R oxidoreductase EGX95_16280 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EGX95_16285 ENOG4105K4P CoA-binding domain protein EGX95_16290 ENOG4105C0H protease EGX95_16295 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX95_16305 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase EGX95_16315 ENOG4105W8X HesB YadR YfhF-family protein EGX95_16345 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) EGX95_16350 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EGX95_16360 ENOG4105BZ1 (ABC) transporter EGX95_16365 ENOG4108I0Z Aconitate hydratase EGX95_16395 ENOG4105E5W Transporter EGX95_16395 ENOG4105E5W Transporter EGX95_16420 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) EGX95_16450 ENOG4107F3J Amp-dependent synthetase and ligase EGX95_16455 ENOG4107ZYJ bioY protein EGX95_16460 ENOG4105CEY Amp-dependent synthetase and ligase EGX95_16475 ENOG4108IMY Transcriptional regulator EGX95_16520 ENOG4107AYK membrAne EGX95_16535 ENOG4105BZU Histidine kinase EGX95_16540 ENOG4105FBA Phospholipase Carboxylesterase EGX95_16545 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase EGX95_16550 ENOG4105CK7 Sodium proline symporter EGX95_16560 ENOG4105CBC glutamate synthase EGX95_16565 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EGX95_16570 ENOG4108VJ1 Transcriptional regulator (CarD family EGX95_16575 ENOG4108903 Formimidoylglutamase EGX95_16600 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) EGX95_16645 ENOG4105EKQ RNA-directed DNA polymerase EGX95_16660 ENOG4107QIV Cytochrome c biogenesis protein EGX95_16675 ENOG4105CH2 amidohydrolase EGX95_16685 ENOG4105CJ1 ABC, transporter EGX95_16700 ENOG4107RSM transcriptional regulator EGX95_16710 ENOG41067MG lrgb family EGX95_16735 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase EGX95_16750 ENOG4105BZ1 (ABC) transporter EGX95_16755 ENOG4105BZ1 (ABC) transporter EGX95_16850 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EGX95_16880 ENOG4105D5T phosphonate abc transporter EGX95_16885 ENOG4108HW3 (ABC) transporter EGX95_16890 ENOG4105CGH 5'-nucleotidase EGX95_16900 ENOG4108SVB resolvase EGX95_16920 ENOG4105K7K Transcriptional regulator EGX95_16925 ENOG4105C5F glutamine synthetase EGX95_16930 ENOG4105KV4 Transcriptional regulator EGX95_16935 ENOG4105CXI aluminum resistance protein EGX95_16940 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EGX95_16945 ENOG4105EN6 Membrane EGX95_16950 ENOG4106F1P AAA ATPase, central domain protein EGX95_16980 ENOG41069ER domain protein EGX95_16985 ENOG4105DM4 PTS System EGX95_16990 ENOG4105DE4 1-phosphofructokinase EGX95_16995 ENOG4105E98 transcriptional regulator DeoR family EGX95_17000 ENOG4107QW4 alcohol dehydrogenase EGX95_17005 ENOG4108SJC Membrane EGX95_17015 ENOG4105C85 amino acid EGX95_17030 ENOG4105TMB Formate nitrite transporter EGX95_17035 ENOG4105K70 DNA-binding protein EGX95_17045 ENOG4105C59 p-type ATPase EGX95_17050 ENOG410681U heavy metal transport detoxification protein EGX95_17055 ENOG4105VPX protein, conserved in bacteria EGX95_17065 ENOG4105NIV Esterase EGX95_17070 ENOG4105E0A ABC, transporter EGX95_17100 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EGX95_17105 ENOG4105D03 DNA-3-methyladenine glycosylase II EGX95_17125 ENOG4105BZU Histidine kinase EGX95_17165 ENOG4105F0V Cell wall hydrolase EGX95_17180 ENOG4105E0M Sulfatase EGX95_17185 ENOG410890F Dynamin family EGX95_17195 ENOG4107QHE Choloylglycine hydrolase EGX95_17220 ENOG4105DA5 (ABC) transporter EGX95_17260 ENOG4105DQU oxidoreductase, subunit beta EGX95_17265 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein EGX95_17270 ENOG4108IGT Dipeptidase EGX95_17275 ENOG4105MCT stage V sporulation protein S EGX95_17280 ENOG4105D48 metallophosphoesterase EGX95_17285 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) EGX95_17305 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase EGX95_17320 ENOG4105XZV Protein of unknown function (DUF3243) EGX95_17325 ENOG4108RKS Short-chain dehydrogenase reductase Sdr EGX95_17345 ENOG4105UIB (ABC) transporter EGX95_17350 ENOG4108JQ9 ABC transporter EGX95_17355 ENOG4105DIH basic membrane EGX95_17360 ENOG4105FDP GntR family transcriptional regulator EGX95_17370 ENOG4107QZI cell division protein FtsK EGX95_17380 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit EGX95_17390 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EGX95_17400 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) EGX95_17405 ENOG4108S0H Dipicolinic acid synthetase, b subunit EGX95_17410 ENOG4105E35 Dipicolinate synthase subunit A EGX95_17420 ENOG4105C1V Peptidase, M16 EGX95_17440 ENOG4105DTN riboflavin biosynthesis protein ribF EGX95_17455 ENOG4105W7A Protein of unknown function (DUF503) EGX95_17465 ENOG4105VHM ribosomal protein EGX95_17470 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination EGX95_17475 ENOG4105CHV Transcription elongation factor NusA EGX95_17485 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) EGX95_17495 ENOG4105DZP Membrane-associated zinc metalloprotease EGX95_17505 ENOG4105KNE Phosphatidate cytidylyltransferase EGX95_17550 ENOG4108HE4 integrase family EGX95_17560 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EGX95_17565 ENOG4105C79 DNA protecting protein DprA EGX95_17570 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha EGX95_17585 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) EGX95_17610 ENOG4105VB6 UPF0109 protein EGX95_17630 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EGX95_17635 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) EGX95_17650 ENOG4105CHR reductase EGX95_17655 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EGX95_17670 ENOG4105CB5 ATP-dependent DNA helicase recG EGX95_17675 ENOG4105DP4 dak2 domain fusion protein ylov EGX95_17680 ENOG4108ZAA Alkaline-shock protein EGX95_17695 ENOG4105FJ0 thiamine EGX95_17700 ENOG4105DJV ribulose-phosphate 3-epimerase EGX95_17710 ENOG4105D9P serine threonine protein kinase EGX95_17715 ENOG4108ZF3 Phosphatase EGX95_17725 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B EGX95_17735 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EGX95_17740 ENOG4105C25 Primosomal protein n' EGX95_17745 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase EGX95_17765 ENOG4105DSJ YicC domain protein EGX95_17775 ENOG4105F23 Fibronectin-binding protein EGX95_17780 ENOG4105DC7 peptidase M24 EGX95_17865 ENOG4105C34 Pseudouridine synthase EGX95_17890 ENOG4105DBK s4 domain protein EGX95_17895 ENOG41067XK integral membrane protein EGX95_17905 ENOG4105DFA alanine racemase domain protein EGX95_17910 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EGX95_17915 ENOG4105WR5 sporulation protein, YlmC YmxH family EGX95_17925 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX95_17935 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) EGX95_17940 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) EGX95_17945 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) EGX95_17960 ENOG4105CNI cell division protein FtsW EGX95_17975 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) EGX95_17980 ENOG4105CJN penicillin-binding protein EGX95_17985 ENOG4105CJN penicillin-binding protein EGX95_17990 ENOG41068DC Essential cell division protein (By similarity) EGX95_18025 ENOG4105KNH Nucleic acid-binding protein EGX95_18140 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EGX95_18150 ENOG4105CAR Terminase, large subunit EGX95_18325 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) EGX95_18335 ENOG41063PX domain protein EGX95_18340 ENOG4105D78 K07001 NTE family protein EGX95_18345 ENOG4105H20 Sporulation integral membrane protein YlbJ EGX95_18355 ENOG4106H78 methyltransferase EGX95_18385 ENOG4107TB6 phosphoglycerate mutase EGX95_18400 ENOG4106UY4 Inherit from COG: Scp-like extracellular EGX95_18415 ENOG4105EKQ RNA-directed DNA polymerase EGX95_18460 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) EGX95_18475 ENOG4105CNI cell division protein FtsW EGX95_18490 ENOG4108IAB Phoh family EGX95_18510 ENOG4105QA2 EGX95_18515 ENOG4105CI3 gtp-binding protein typa EGX95_18525 ENOG4105ECY inositol monophosphatase EGX95_18545 ENOG4105CXN decarboxylase EGX95_18595 ENOG4105CPP Dehydrogenase, E1 component EGX95_18610 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EGX95_18615 ENOG4108X4Q Hydrolase EGX95_18630 ENOG4105CN5 Metallo-Beta-Lactamase EGX95_18635 ENOG4107ZYR domain protein EGX95_18670 ENOG4108XRC Protein of unknown function (DUF458) EGX95_18675 ENOG4107IN1 Protein of unknown function (DUF1797) EGX95_18690 ENOG4105EPM Diguanylate phosphodiesterase EGX95_18695 ENOG4105K6S Short-chain dehydrogenase reductase Sdr EGX95_18710 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) EGX95_18720 ENOG4105UIN EGX95_18785 ENOG4108HGU Histidine kinase EGX95_18795 ENOG4105CHM Aminotransferase EGX95_18800 ENOG4105FKQ transcriptional regulator EGX95_18805 ENOG4105EG2 ABC transporter, permease EGX95_18815 ENOG4107FKK extracellular solute-binding protein family 1 EGX95_18825 ENOG4105CG3 alpha amylase, catalytic region EGX95_18870 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) EGX95_18875 ENOG4105CHU acetyl-coa acetyltransferase EGX95_18910 ENOG4105K7K Transcriptional regulator EGX95_18915 ENOG4105DTD Dehydrogenase EGX95_18940 ENOG4105EKQ RNA-directed DNA polymerase EGX95_18945 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase EGX95_18985 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EGX95_18995 ENOG4106TD9 Diguanylate cyclase EGX95_19015 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) EGX95_19030 ENOG4105CID antiterminator EGX95_19040 ENOG4105FDP GntR family transcriptional regulator EGX95_19050 ENOG4105CE4 GlcNAc 6-P deacetylase EGX95_19095 ENOG4107ZE5 PPIases accelerate the folding of proteins EGX95_19100 ENOG4105PTM secreted protein EGX95_19105 ENOG4105J7I hydrolase EGX95_19115 ENOG4105G6R Stage v sporulation protein ae EGX95_19125 ENOG4105CZ3 stage V sporulation protein ad EGX95_19130 ENOG41090VF Stage v sporulation protein ac EGX95_19150 ENOG4105C8J )-transporter EGX95_19155 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX95_19165 ENOG41082AN stage II sporulation protein EGX95_19170 ENOG4105DZ1 carboxypeptidase EGX95_19180 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family EGX95_19185 ENOG4105DVE abc transporter atp-binding protein EGX95_19215 ENOG4105D7N magnesium and cobalt transport protein CorA EGX95_19240 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EGX95_19250 ENOG4105I3K Ferric uptake regulator, Fur family EGX95_19255 ENOG4105MZ9 stage II sporulation protein m EGX95_19275 ENOG4105CPC Aldo Keto reductase EGX95_19285 ENOG4105RHY Pfam:UPF0157 EGX95_19305 ENOG4107SKW Inherit from COG: Alpha beta hydrolase EGX95_19315 ENOG4105ETE Transcriptional regulator (LacI family EGX95_19320 ENOG4108YM7 Gcn5-related n-acetyltransferase EGX95_19340 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) EGX95_19345 ENOG4108R6K riboflavin synthase, subunit alpha EGX95_19370 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EGX95_19375 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EGX95_19390 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EGX95_19400 ENOG4105DFD Na H antiporter EGX95_19405 ENOG4105CGH 5'-nucleotidase EGX95_19460 ENOG4108IXY short-chain dehydrogenase reductase EGX95_19465 ENOG41069FQ Metallo-beta-lactamase superfamily EGX95_19470 ENOG4105II7 pyrroline-5-carboxylate reductase EGX95_19475 ENOG4105EJQ L-serine dehydratase EGX95_19505 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EGX95_19515 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) EGX95_19520 ENOG4105D9U N-acetyltransferase EGX95_19530 ENOG4108VZI ErfK ybiS ycfS ynhG family protein EGX95_19535 ENOG4108QEG Membrane EGX95_19540 ENOG4105CDA abc transporter atp-binding protein EGX95_19545 ENOG4105E5Q amino acid AbC transporter EGX95_19550 ENOG4108HW3 (ABC) transporter EGX95_19570 ENOG4108QY0 Membrane EGX95_19580 ENOG4105C7S Dehydrogenase EGX95_19585 ENOG4105CPP Dehydrogenase, E1 component EGX95_19605 ENOG4107RDP Dehydrogenase EGX95_19620 ENOG4108JUB Transcriptional regulator EGX95_19630 ENOG4108QXE glycerophosphoryl diester phosphodiesterase EGX95_19640 ENOG4107QQR Sporulation EGX95_19650 ENOG4105S1Z Stage IV sporulation protein B EGX95_19655 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) EGX95_19665 ENOG4105DX0 Hemolysin A EGX95_19675 ENOG4105CTB Polyprenyl synthetase EGX95_19700 ENOG4108ZSR alkaline shock protein EGX95_19705 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EGX95_19730 ENOG410644B Stage III sporulation protein af EGX95_19740 ENOG4105KQ4 Stage iii sporulation protein ad EGX95_19745 ENOG4108CQH stage III sporulation protein AC EGX95_19750 ENOG4105KR5 Stage iii sporulation protein EGX95_19755 ENOG4105CD2 stage iii sporulation protein aa EGX95_19780 ENOG4105DC7 peptidase M24 EGX95_19795 ENOG4105CBJ Metal-dependent enzyme EGX95_19835 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) EGX95_19840 ENOG4105WZW rhodanese family EGX95_19860 ENOG41080TC multidrug resistance protein EGX95_19895 ENOG4105CJ1 ABC, transporter EGX95_19900 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family EGX95_19930 ENOG4105C0D helicase EGX95_20055 ENOG4105C3R Methionine synthase EGX95_20065 ENOG4105C28 cystathionine EGX95_20070 ENOG4105C28 cystathionine EGX95_20090 ENOG4105C5X domain protein EGX95_20100 ENOG4105DKQ ROK family EGX95_20110 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase EGX95_20125 ENOG4108UTW Plays a role in the regulation of phosphate uptake EGX95_20130 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) EGX95_20135 ENOG4105E2Z phosphate ABC transporter (Permease EGX95_20140 ENOG4105C8U phosphate abc transporter EGX95_20145 ENOG4105PWN phosphate abc transporter EGX95_20150 ENOG4107RF6 penicillin-binding protein EGX95_20160 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EGX95_20185 ENOG4105N80 Ferric uptake regulator, Fur family EGX95_20195 ENOG4105FDK ABC transporter EGX95_20200 ENOG4108JYZ YitT family EGX95_20205 ENOG41069ZM Protein of unknown function (DUF2624) EGX95_20230 ENOG4105EGD dinuclear metal center protein, YbgI family EGX95_20245 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX95_20250 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) EGX95_20275 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) EGX95_20280 ENOG4105KG3 cytidine deaminase EGX95_20285 ENOG4107YR5 Diacylglycerol kinase EGX95_20295 ENOG4105CTJ Metal Dependent Phosphohydrolase EGX95_20300 ENOG4105C9A Phoh family EGX95_20310 ENOG41068P3 sporulation protein YqfC EGX95_20315 ENOG4105KTH gatB Yqey EGX95_20325 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) EGX95_20330 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) EGX95_20360 ENOG4105CSA Coproporphyrinogen iii oxidase EGX95_20365 ENOG4105KVH Transcriptional regulator EGX95_20390 ENOG4105TQK DNA polymerase iii, delta' subunit EGX95_20400 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 EGX95_20405 ENOG4108UK2 deaminase EGX95_20410 ENOG4105KQC Competence protein EGX95_20420 ENOG4105DXX methyltransferase EGX95_20430 ENOG4108WF2 Metal Dependent Phosphohydrolase EGX95_20440 ENOG410812S Rna-binding protein EGX95_20450 ENOG4105CQW ribosome biogenesis GTPase YqeH EGX95_20455 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase EGX95_20470 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX95_20500 ENOG4105G6Z alkaline phosphatase EGX95_20505 ENOG4105KEG ribosomal-protein-alanine acetyltransferase EGX95_20510 ENOG4108MUZ hydrolase EGX95_20545 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin EGX95_20550 ENOG4105MIR Phenylalanine 4-monooxygenase EGX95_20560 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase EGX95_20600 ENOG4105S6R Iron-hydroxamate transporter permease subunit EGX95_20605 ENOG4108HUF Transporter EGX95_20615 ENOG4108EKI Dehydrogenase EGX95_20620 ENOG4105C28 cystathionine EGX95_20650 ENOG4107XRG penicillin-binding protein EGX95_20665 ENOG4105CFP Peptidase U32 EGX95_20670 ENOG4105XYU peptidase (U32 family) EGX95_20675 ENOG4108VQJ O-methyltransferase EGX95_20680 ENOG4105HHA aminodeoxychorismate lyase EGX95_20710 ENOG4105C02 permease EGX95_20725 ENOG41060CR EGX95_20730 ENOG4105C7H Helicase, RecD TraA family EGX95_20745 ENOG4105C3J Cysteine desulfurase EGX95_20755 ENOG4105D1H recombination factor protein RarA EGX95_20760 ENOG4108VCI transcription factor, rsfa family EGX95_20770 ENOG4105CUZ uba thif-type nad fad binding protein EGX95_20795 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EGX95_20805 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) EGX95_20810 ENOG41076HS cation diffusion facilitator family transporter EGX95_20815 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EGX95_20825 ENOG4105CKP Polysaccharide Biosynthesis Protein EGX95_20830 ENOG4108QG2 Membrane EGX95_20840 ENOG4105VIE preprotein translocase, subunit YajC EGX95_20855 ENOG41061AI Protein of unknown function (DUF2905) EGX95_20895 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase EGX95_20900 ENOG4108IYU L-aspartate oxidase EGX95_20915 ENOG4108RPX mosc domain containing protein EGX95_20920 ENOG4105CQC Prephenate dehydratase EGX95_20940 ENOG4105EWM Histidine kinase EGX95_20970 ENOG4105C03 ribonuclease EGX95_20985 ENOG4107QMS site-determining protein EGX95_21000 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) EGX95_21005 ENOG4105DFF Rod shape-determining protein mreb EGX95_21030 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase EGX95_21055 ENOG41068KH stage VI sporulation protein D EGX95_21065 ENOG4105D52 delta-aminolevulinic acid dehydratase EGX95_21090 ENOG4105K56 Transcriptional regulator EGX95_21110 ENOG4108IUQ atp-dependent protease EGX95_21140 ENOG4108QCI YvbH-like oligomerisation region EGX95_21165 ENOG4105M59 Phosphodiesterase, mj0936 family EGX95_21170 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) EGX95_21180 ENOG4108XJQ germination protein EGX95_21190 ENOG4108PCX Major Facilitator EGX95_21200 ENOG4105KBX Transcriptional regulator, TetR family EGX95_21215 ENOG4105PFC Transcriptional regulator EGX95_21230 ENOG41067S9 phage shock protein C, PspC EGX95_21235 ENOG4108JCI Transcriptional regulator EGX95_21245 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) EGX95_21250 ENOG4108Z40 Transcriptional regulator EGX95_21255 ENOG4105RHA ABC transporter, permease EGX95_21260 ENOG4108IUX (ABC) transporter EGX95_21265 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family EGX95_21270 ENOG4105ER2 Ompa motb domain protein EGX95_21275 ENOG4105E14 MotA TolQ exbB proton channel EGX95_21280 ENOG4108VXD carboxy-peptidase EGX95_21290 ENOG4105E33 succinate dehydrogenase EGX95_21300 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit EGX95_21315 ENOG4105K63 Thioredoxin EGX95_21320 ENOG4105C10 Electron transfer flavoprotein EGX95_21325 ENOG4105BZJ Electron transfer flavoprotein EGX95_21330 ENOG41060WC Enoyl-CoA hydratase EGX95_21335 ENOG4107Z3H Transcriptional regulator, TetR family EGX95_21340 ENOG4105CEY Amp-dependent synthetase and ligase EGX95_21380 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EGX95_21390 ENOG4105DR4 Methyltransferase EGX95_21405 ENOG4105KFN sortase, SrtB family EGX95_21410 ENOG4105E0A ABC, transporter EGX95_21425 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) EGX95_21430 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) EGX95_21440 ENOG4105FE9 pseudouridine synthase EGX95_21450 ENOG4105DCG PHP domain protein EGX95_21500 ENOG4108RWN rrna methyltransferase EGX95_21520 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX95_21525 ENOG4105CW7 secretion protein, HlyD family EGX95_21530 ENOG4108JGH Tetr family transcriptional regulator EGX95_21535 ENOG4105CN9 Peptidase m42 family protein EGX95_21555 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) EGX95_21560 ENOG4105C22 threonyL-tRNA synthetase EGX95_21565 ENOG4108TDW sporulation protein YtxC EGX95_21585 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) EGX95_21590 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EGX95_21595 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) EGX95_21610 ENOG4105C2M dna polymerase I EGX95_21615 ENOG4105BZU Histidine kinase EGX95_21620 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EGX95_21640 ENOG4108HMX isocitrate dehydrogenase (NADP) EGX95_21645 ENOG4105BZN citrate synthase EGX95_21660 ENOG4108REF Sporulation integral membrane protein ytvi EGX95_21665 ENOG4105FS0 cytoplasmic membrane protein EGX95_21690 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family EGX95_21695 ENOG4105C6K Malic enzyme EGX95_21700 ENOG4105C0B DNA polymerase III (alpha subunit) EGX95_21705 ENOG4105VV2 EGX95_21715 ENOG4105SFS phosphoesterase RecJ domain protein EGX95_21755 ENOG4105DC7 peptidase M24 EGX95_21795 ENOG41082W1 Cupin 2, conserved barrel domain protein EGX95_21815 ENOG4107YZX Universal stress protein EGX95_21880 ENOG4108JYZ YitT family EGX95_21910 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) EGX95_21915 ENOG4105KBJ sporulation protein ytfj EGX95_21930 ENOG4105EFZ amidohydrolase EGX95_21940 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EGX95_21965 ENOG4105C5Q Transcriptional regulator EGX95_21975 ENOG4105U5Y Transcriptional regulator EGX95_21985 ENOG4105C28 cystathionine EGX95_22015 ENOG4105EMN RNA polymerase sigma factor EGX95_22035 ENOG4105F1V Acetoin utilization protein EGX95_22040 ENOG4105W87 Cbs domain EGX95_22045 ENOG4105DGU Histone deacetylase EGX95_22060 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EGX95_22070 ENOG4105EP9 oxidoreductase EGX95_22100 ENOG4105ETE Transcriptional regulator (LacI family EGX95_22125 ENOG4105C88 aminopeptidase EGX95_22170 ENOG4108VDD TRNA binding domain protein EGX95_22200 ENOG4105C8F Beta-lactamase domain protein EGX95_22215 ENOG4108V15 phosphotransferase enzyme family EGX95_22220 ENOG4108IUM Glycogen debranching enzyme EGX95_22230 ENOG4107QSE Dipeptidase EGX95_22235 ENOG4105YW5 deoR family transcriptional regulator EGX95_22250 ENOG4105CBX hi0933 family EGX95_22290 ENOG4108VJ1 Transcriptional regulator (CarD family EGX95_22295 ENOG4107EXU Short-chain dehydrogenase reductase Sdr EGX95_22315 ENOG4108ZAF Molybdopterin EGX95_22320 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein EGX95_22325 ENOG4105CVM Molybdenum cofactor synthesis domain protein EGX95_22335 ENOG4105D06 uba thif-type nad fad binding protein EGX95_22340 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EGX95_22365 ENOG41085GJ domain protein EGX95_22375 ENOG4105DWV Homoserine O-trans-acetylase EGX95_22385 ENOG4108B31 Spore germination protein EGX95_22415 ENOG410605W Major Facilitator EGX95_22420 ENOG4107S91 Sodium hydrogen exchanger EGX95_22425 ENOG4105NCW Trka-c domain protein EGX95_22445 ENOG4105C19 ABC transporter EGX95_22465 ENOG4105N5T Radical SAM Protein EGX95_22480 ENOG4105CIG ABC transporter EGX95_22520 ENOG4105E8V Alpha Beta Hydrolase Fold protein EGX95_22525 ENOG4108Z0R Transferase EGX95_22530 ENOG4105YVM Phosphoesterase, PA-phosphatase related EGX95_22535 ENOG4105BZF Glycosyl transferase (Group 1 EGX95_22545 ENOG4108RIR Molybdenum cofactor biosynthesis protein EGX95_22600 ENOG4105BZU Histidine kinase EGX95_22605 ENOG4105BZU Histidine kinase EGX95_22610 ENOG4107S9D Alpha beta hydrolase EGX95_22615 ENOG4107T7U Sulfatase EGX95_22635 ENOG4105D2X ABC transporter substrate-binding protein EGX95_22645 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component EGX95_22705 ENOG4108V2W Carbonate dehydratase EGX95_22710 ENOG4105C4M (Ubiquinol oxidase) subunit I EGX95_22715 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EGX95_22760 ENOG41087YS Phage shock protein A EGX95_22795 ENOG4105BZU Histidine kinase EGX95_22800 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX95_22830 ENOG4108UGV hypoxanthine phosphoribosyltransferase EGX95_22835 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) EGX95_22860 ENOG4105C19 ABC transporter EGX95_22875 ENOG4107ZTW SNARE associated Golgi EGX95_22900 ENOG4105C19 ABC transporter EGX95_22905 ENOG41086D8 Transcriptional regulator EGX95_22915 ENOG41082BM Transcriptional regulator, arsr family EGX95_22955 ENOG4105C6Z Gluconate EGX95_22960 ENOG4105FDP GntR family transcriptional regulator EGX95_22980 ENOG41069H0 dihydroorotase EC 3.5.2.3 EGX95_23000 ENOG4105DTQ mandelate racemase muconate lactonizing EGX95_23010 ENOG4108IPT Naphthoate synthase EGX95_23015 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) EGX95_23025 ENOG4105E4F Isochorismate synthase EGX95_23030 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase EGX95_23040 ENOG4105VEQ Cold shock protein EGX95_23090 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin EGX95_23190 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation EGX95_23225 ENOG4105KT7 mgtC SapB transporter EGX95_23230 ENOG4107PBV potassium channel EGX95_23250 ENOG4105WG9 Conserved Protein EGX95_23260 ENOG4105CHM Aminotransferase EGX95_23265 ENOG4108ZB6 transcriptional regulator AsnC family EGX95_23270 ENOG4105C5I Dehydrogenase EGX95_23275 ENOG4108MUZ hydrolase EGX95_23285 ENOG4105C87 Aminotransferase class I and II EGX95_23295 ENOG4105Y38 Kinase-associated protein B EGX95_23305 ENOG4107R3E Citrate transporter EGX95_23320 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) EGX95_23325 ENOG4105KA0 thioesterase Superfamily protein EGX95_23345 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EGX95_23365 ENOG41069ER domain protein EGX95_23380 ENOG4105CEP NADH dehydrogenase EGX95_23405 ENOG4105EWC Purine nucleoside phosphorylase EGX95_23425 ENOG4108YX9 iron--sulfur cluster insertion protein erpA EGX95_23450 ENOG4108JJA ABC, transporter EGX95_23455 ENOG4105C4B ABC transporter, permease EGX95_23465 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EGX95_23510 ENOG41083MR nifu domain-containing protein EGX95_23525 ENOG4108W5N phosphatidylglycerophosphatase a EGX95_23540 ENOG4105DYS nad(p)h dehydrogenase (quinone) EGX95_23545 ENOG4105D4U had-superfamily hydrolase, subfamily iia EGX95_23560 ENOG4105CBT Fructose-1,6-bisphosphatase EGX95_23580 ENOG4105MMD transcriptional regulator EGX95_23585 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) EGX95_23590 ENOG4107TXC Transcriptional regulator EGX95_23595 ENOG41090T1 Membrane EGX95_23620 ENOG4105FAA peptidase M23 EGX95_23630 ENOG4105KZD Domain of unknown function (DUF1805) EGX95_23635 ENOG4107R8B 5'-nucleotidase EGX95_23645 ENOG4105DIW FeS assembly protein SUFB EGX95_23650 ENOG4108UNV SUF system FeS assembly protein, NifU family EGX95_23655 ENOG4105C9B Cysteine desulfurase EGX95_23660 ENOG4105JRK feS assembly protein SufD EGX95_23665 ENOG4105C3K feS assembly ATPase SufC EGX95_23670 ENOG4105D01 (LipO)protein EGX95_23675 ENOG4105D01 (LipO)protein EGX95_23680 ENOG4108UMI ABC transporter, permease EGX95_23715 ENOG41080E8 Transcriptional regulator, Spx MgsR family EGX95_23790 ENOG4108W8B Beta-lactamase domain protein EGX95_23795 ENOG4105C1G acyl-Coa dehydrogenase EGX95_23805 ENOG4105CHU acetyl-coa acetyltransferase EGX95_23825 ENOG4105DZ1 carboxypeptidase EGX95_23845 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer EGX95_23850 ENOG4105D7V transposase EGX95_23865 ENOG4105F27 Major Facilitator EGX95_23870 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) EGX95_23880 ENOG4107R7I amino acid EGX95_23910 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins EGX95_23920 ENOG4107AYK membrAne EGX95_23960 ENOG4107ZTW SNARE associated Golgi EGX95_23970 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EGX95_23975 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX95_23980 ENOG4105BZU Histidine kinase EGX95_24005 ENOG4105C8Q Methyl-accepting chemotaxis EGX95_24010 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer EGX95_24015 ENOG4105VG1 fes assembly suf system protein EGX95_24020 ENOG4105D4Y metalloprotease EGX95_24045 ENOG4107S91 Sodium hydrogen exchanger EGX95_24050 ENOG4105NCW Trka-c domain protein EGX95_24065 ENOG4108RMU ferritin dps family protein EGX95_24085 ENOG4108URH decarboxylase EGX95_24105 ENOG4105D9N nucleoside EGX95_24110 ENOG4105D9N nucleoside EGX95_24125 ENOG4108RYK Nad-dependent epimerase dehydratase EGX95_24140 ENOG4105CV8 reductase EGX95_24145 ENOG4105F27 Major Facilitator EGX95_24150 ENOG4105KVH Transcriptional regulator EGX95_24165 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) EGX95_24170 ENOG4105D4A Cell wall formation (By similarity) EGX95_24195 ENOG4105C8Q Methyl-accepting chemotaxis EGX95_24205 ENOG4105WMR Protein CrcB homolog EGX95_24230 ENOG4105C5H ABC transporter EGX95_24235 ENOG4108MK9 spermidine N(1)-acetyltransferase EGX95_24240 ENOG4108VY7 phosphate-starvation-inducible protein PsiE EGX95_24250 ENOG4108IPW abc transporter atp-binding protein EGX95_24255 ENOG4105CM4 permease protein EGX95_24285 ENOG4105C19 ABC transporter EGX95_24305 ENOG4107ZTW SNARE associated Golgi EGX95_24350 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) EGX95_24355 ENOG41086D8 Transcriptional regulator EGX95_24370 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) EGX95_24375 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX95_24385 ENOG4108ZHR arsR family transcriptional regulator EGX95_24390 ENOG4105DHF Membrane EGX95_24410 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) EGX95_24420 ENOG4105XZU Preprotein translocase, subunit SecG EGX95_24425 ENOG41067MG lrgb family EGX95_24475 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX95_24495 ENOG41090VF Stage v sporulation protein ac EGX95_24500 ENOG4105CZ3 stage V sporulation protein ad EGX95_24515 ENOG4108QY0 Membrane EGX95_24520 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EGX95_24530 ENOG4105KRI phosphocarrier protein (HPr EGX95_24540 ENOG4105CHW UPF0052 protein EGX95_24550 ENOG4108Z4K mutator MutT protein EGX95_24560 ENOG4105C3M thioredoxin reductase EGX95_24570 ENOG4108S4C acetyltransferase EGX95_24590 ENOG41086DT Membrane protein of unknown function EGX95_24600 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) EGX95_24615 ENOG4107TXC Transcriptional regulator EGX95_24650 ENOG4105DUM transcriptional regulator, lysR family EGX95_24660 ENOG4108WS4 fmn reductase EGX95_24665 ENOG4105C5H ABC transporter EGX95_24675 ENOG4105BZ1 (ABC) transporter EGX95_24685 ENOG4105CN1 protease EGX95_24690 ENOG4105CRP Part of the ABC transporter FtsEX involved in EGX95_24695 ENOG4105CAK Cell division ATP-binding protein ftsE EGX95_24720 ENOG4105MS2 ribosomal subunit Interface protein EGX95_24725 ENOG4105VEQ Cold shock protein EGX95_24730 ENOG41081UC Inherit from COG: Competence protein EGX95_24740 ENOG4105K4H Nlp p60 protein EGX95_24745 ENOG4105KVH Transcriptional regulator EGX95_24755 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein EGX95_24760 ENOG4108KGH TRANSCRIPTIONal EGX95_24765 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase EGX95_24770 ENOG4105C6Y Udp-glucose 6-dehydrogenase EGX95_24775 ENOG4105ESV Glycosyl transferase, family 4 EGX95_24785 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EGX95_24805 ENOG4105F8D glycoside hydrolase family 4 EGX95_24810 ENOG4105VCP PTS System EGX95_24815 ENOG4105CK1 PTS System EGX95_24825 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) EGX95_24845 ENOG4105VCP PTS System EGX95_24855 ENOG4105VZJ PTS System EGX95_24875 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase EGX95_24900 ENOG4105ECB domain protein EGX95_24905 ENOG4107RSM transcriptional regulator EGX95_24935 ENOG4105DAA L-lactate EGX95_24945 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) EGX95_24960 ENOG4105E0M Sulfatase EGX95_24985 ENOG4107R8N Glycosyl transferase, family 2 EGX95_24995 ENOG4105C94 Transporter EGX95_25005 ENOG41069ER domain protein EGX95_25030 ENOG4105KBK Zinc finger, swim domain protein EGX95_25035 ENOG4105C0D helicase EGX95_25065 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX95_25075 ENOG4107RBB ABC transporter, permease EGX95_25080 ENOG4105C19 ABC transporter EGX95_25090 ENOG4105CXY transporter EGX95_25105 ENOG4105BZU Histidine kinase EGX95_25110 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX95_25120 ENOG4108KGH TRANSCRIPTIONal EGX95_25130 ENOG4105C6Y Udp-glucose 6-dehydrogenase EGX95_25165 ENOG4105D3Q Sugar transferase EGX95_25170 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase EGX95_25180 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EGX95_25185 ENOG4108RB3 Capsular polysaccharide biosynthesis protein EGX95_25190 ENOG4107YJ4 chain length determinant protein EGX95_25195 ENOG4105HTX biosynthesis protein EGX95_25200 ENOG4108QV3 biosynthesis protein EGX95_25215 ENOG4105MT0 Sporulation transcriptional regulator spoiiid EGX95_25225 ENOG4105FRN stage II sporulation protein EGX95_25240 ENOG4105DY9 regulatoR EGX95_25260 ENOG4106778 Protein of unknown function (DUF1146) EGX95_25265 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) EGX95_25270 ENOG4105C8S subunit m EGX95_25275 ENOG4105D65 subunit l EGX95_25305 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain EGX95_25315 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain EGX95_25320 ENOG4105BZU Histidine kinase EGX95_25370 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) EGX95_25375 ENOG41062M3 atp synthase EGX95_25405 ENOG4108YZG isomerase EGX95_25420 ENOG4108VGI doxx family EGX95_25425 ENOG4107XC4 flavin reductase domain protein, FMN-binding EGX95_25440 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) EGX95_25450 ENOG4108ZXQ stage ii sporulation protein r EGX95_25455 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EGX95_25460 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) EGX95_25475 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) EGX95_25480 ENOG4105CBT Fructose-1,6-bisphosphatase EGX95_25485 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) EGX95_25520 ENOG4105C1G acyl-Coa dehydrogenase EGX95_25525 ENOG4105C1G acyl-Coa dehydrogenase EGX95_25530 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EGX95_25540 ENOG4105DF6 Fe-S oxidoreductase EGX95_25555 ENOG4105BZU Histidine kinase EGX95_25585 ENOG4105BZU Histidine kinase EGX95_25590 ENOG4105KCT ABC transporter EGX95_25595 ENOG4108M15 ABC transporter EGX95_25600 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) EGX95_25610 ENOG4105IIU Aminopeptidase EGX95_25630 ENOG4105EMN RNA polymerase sigma factor EGX95_25645 ENOG410684U Domain of unknown function (DUF1934) EGX95_25670 ENOG4105CYW agmatinase EGX95_25680 ENOG4105DXB Major Facilitator superfamily EGX95_25685 ENOG4107SWG transcriptional regulator MERR family EGX95_25690 ENOG4108QXE glycerophosphoryl diester phosphodiesterase EGX95_25695 ENOG4105BZ4 penicillin-binding protein EGX95_25700 ENOG4108XFG YwhD family EGX95_25705 ENOG4108Z4T Peptidase M50 EGX95_25710 ENOG41069HH 4-oxalocrotonate tautomerase EGX95_25715 ENOG4105DCI Phosphohydrolase EGX95_25720 ENOG4108V5C ABC transporter EGX95_25725 ENOG4105E0A ABC, transporter EGX95_25730 ENOG4105EHG Permease protein EGX95_25735 ENOG4105DQ5 transport system permease protein EGX95_25745 ENOG4108VCI transcription factor, rsfa family EGX95_25760 ENOG4108IJ2 phosphate acetyltransferase EGX95_25775 ENOG4108VKI Cell wall hydrolase EGX95_25795 ENOG4107SVH Potassium channel protein EGX95_25805 ENOG410667J hydrolase EGX95_25810 ENOG4105VCH membrane EGX95_25820 ENOG4108TU7 Inherit from COG: (ABC) transporter EGX95_25825 ENOG4105CJ1 ABC, transporter EGX95_25830 ENOG41090WU lipolytic protein G-D-S-L family EGX95_25845 ENOG4105D6E homoserine dehydrogenase EGX95_25870 ENOG4108Y4K DNA-binding transcriptional activator EGX95_25880 ENOG4105WH1 Two component transcriptional regulator luxr family EGX95_25885 ENOG4105BZU Histidine kinase EGX95_25890 ENOG4105DWF phosphomethylpyrimidine kinase EGX95_25895 ENOG4105BZU Histidine kinase EGX95_25900 ENOG4105VCD cytoplasmic protein EGX95_25905 ENOG4105D22 carbon starvation protein EGX95_25910 ENOG4105DY9 regulatoR EGX95_25915 ENOG41079KZ Major Facilitator Superfamily EGX95_25930 ENOG4105CG5 Glycosyl transferase (Group 1 EGX95_25940 ENOG4105EN6 Membrane EGX95_25945 ENOG4106YBV Methyl-accepting chemotaxis EGX95_25955 ENOG4108S4H thioesterase Superfamily protein EGX95_25960 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) EGX95_25975 ENOG4105K64 Glycosyl transferase, family 2 EGX95_25990 ENOG4105C5H ABC transporter EGX95_25995 ENOG41067SE Tetr family transcriptional regulator EGX95_26005 ENOG4105E0X reductase EGX95_26010 ENOG4106F5Q Membrane EGX95_26025 ENOG4105DY9 regulatoR EGX95_26030 ENOG4108HRK Histidine kinase EGX95_26035 ENOG4107RGD Major Facilitator superfamily EGX95_26055 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EGX95_26065 ENOG4105IW1 AmiS UreI transporter EGX95_26100 ENOG4105CMR udp-glucose 4-epimerase EGX95_26105 ENOG4108UT2 hemolysin iii EGX95_26115 ENOG4105C1J atp-dependent rna helicase EGX95_26125 ENOG4105DPN Oligoendopeptidase f EGX95_26145 ENOG4105C0H protease EGX95_26150 ENOG4105Q2H domain protein EGX95_26165 ENOG4105BZU Histidine kinase EGX95_26170 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX95_26200 ENOG4105CDU Replicative dna helicase EGX95_26210 ENOG4105BZR domain protein EGX95_26215 ENOG4108XMW Membrane EGX95_26225 ENOG4108UUM single-stranded DNA-binding protein EGX95_26235 ENOG4105C3G gtp-binding protein EGX95_26240 ENOG4105VDK protein, conserved in bacteria EGX95_26245 ENOG4105D8X mechanosensitive ion channel EGX95_26250 ENOG4108ZDA Sporulation protein YyaC EGX95_26255 ENOG4105FA0 parb-like partition protein EGX95_26260 ENOG4107QJE Chromosome Partitioning Protein EGX95_26290 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins EGX95_26310 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EGX95_26315 ENOG410848D S4 domain protein YaaA EGX95_26330 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EGX95_26365 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EGX95_26400 ENOG4105ZMH deoxynucleoside kinase EGX95_26410 ENOG4105GTG Isochorismatase EGX95_26415 ENOG4108Z6B deaminase EGX95_26425 ENOG4105C6E dna polymerase iii EGX95_26445 ENOG41067KS pro-sigma K processing EGX95_26480 ENOG4105CXN decarboxylase EGX95_26490 ENOG4105FA2 dna polymerase iii EGX95_26495 ENOG4105MA4 psp1 domain protein EGX95_26505 ENOG41060K3 Methyltransferase EGX95_26515 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) EGX95_26520 ENOG4105KRN Transcriptional regulator, abrb family EGX95_26530 ENOG4105F8V Hydrolase, tatD family EGX95_26535 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) EGX95_26545 ENOG4105XFA sporulation peptidase YabG EGX95_26550 ENOG4105W42 Veg protein EGX95_26565 ENOG4105DFT pur operon repressor EGX95_26570 ENOG4105KME endoribonuclease L-psp EGX95_26585 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EGX95_26600 ENOG4108JA2 transcriptioN-repair coupling factor EGX95_26605 ENOG4108M14 stage v sporulation protein t EGX95_26615 ENOG4108IY2 MazG family EGX95_26620 ENOG41082I2 s4 domain protein EGX95_26625 ENOG4105VYY sporulation protein yabp EGX95_26640 ENOG41060GV RNA binding s1 domain protein EGX95_26665 ENOG4108UGV hypoxanthine phosphoribosyltransferase EGX95_26670 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) EGX95_26685 ENOG4105C6T cysteine synthase EGX95_26690 ENOG4105CRQ synthase (Component I) EGX95_26695 ENOG4105DDQ anthranilate synthase EGX95_26700 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 EGX95_26705 ENOG4105EEI dihydropteroate synthase EGX95_26710 ENOG4105KRF dihydroneopterin aldolase EGX95_26715 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EGX95_26725 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EGX95_26815 ENOG4108Z0C Uvrb UvrC protein EGX95_26830 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) EGX95_26840 ENOG4105CTP PilT protein domain protein EGX95_26860 ENOG4105D7W serine acetyltransferase EGX95_26875 ENOG4105C2N RNA methyltransferase TrmH family group 3 EGX95_26880 ENOG4105M0M Tetracycline resistance protein EGX95_26885 ENOG4105QIV RNA polymerase EGX95_26900 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) EGX95_26925 ENOG4107Y49 methyltransferase EGX95_26940 ENOG4105XPM ribosomal protein EGX95_27050 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) EGX95_27075 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EGX95_27085 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EGX95_27095 ENOG41067V7 50S ribosomal protein L36 EGX95_27125 ENOG4108JJB ABC transporter EGX95_27130 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) EGX95_27160 ENOG4105D1F ATP-binding protein EGX95_27175 ENOG4108NMV polysaccharide deacetylase EGX95_27255 ENOG4105C8B TIGR00159 family EGX95_27260 ENOG4107U5W ybbr family EGX95_27280 ENOG4108VQT Alpha beta hydrolase fold protein EGX95_27290 ENOG4105CMG Carbohydrate kinase EGX95_27300 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) EGX95_27335 ENOG4108PSK reductase EGX95_27340 ENOG4108UMI ABC transporter, permease EGX95_27350 ENOG4105D01 (LipO)protein EGX95_27355 ENOG4105EE1 crotonyl-CoA reductase EGX95_27365 ENOG4105IQ5 FAD linked oxidase domain protein EGX95_27380 ENOG4105C2C drug resistance transporter, Bcr CflA EGX95_27395 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EGX95_27400 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EGX95_27405 ENOG4105C3U ABC transporter EGX95_27410 ENOG4108JQ7 (ABC) transporter EGX95_27430 ENOG4108J59 Extracellular solute-binding protein, family 5 EGX95_27435 ENOG4108J59 Extracellular solute-binding protein, family 5 EGX95_27450 ENOG4107XDY Nicotinamide Mononucleotide Transporter EGX95_27460 ENOG4105E0C molybdate abc transporter EGX95_27465 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein EGX95_27470 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family EGX95_27500 ENOG4105F6E Acyl-transferase EGX95_27520 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) EGX95_27530 ENOG4108RE7 deoxyribonuclease EGX95_27535 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) EGX95_27555 ENOG4105C5H ABC transporter EGX95_27565 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein EGX95_27570 ENOG4105DEF Extracellular solute-binding protein, family 5 EGX95_27580 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EGX95_27585 ENOG4105C3U ABC transporter EGX95_27590 ENOG4108JQ7 (ABC) transporter EGX95_27595 ENOG410667J hydrolase EGX95_27625 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase EGX95_27630 ENOG4105ERH Fumarylacetoacetate hydrolase EGX95_27640 ENOG4105CUB amino acid EGX95_27645 ENOG4108SC4 )-transporter EGX95_27650 ENOG4105CPF Cell wall formation (By similarity) EGX95_27655 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) EGX95_27680 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein EGX95_27685 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EGX95_27695 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) EGX95_27795 ENOG4105K8N protein family UPF0079, ATPase EGX95_27800 ENOG41072GX Peptidase M22 Glycoprotease EGX95_27805 ENOG410801F ribosomal-protein-alanine acetyltransferase EGX95_27815 ENOG4105C5H ABC transporter EGX95_27830 ENOG4108TYN CAAX amino terminal protease family protein EGX95_27850 ENOG4105C7N Xanthine uracil vitamin C permease EGX95_27860 ENOG4105BZU Histidine kinase EGX95_27890 ENOG4107ZXU DSBA oxidoreductase EGX95_27920 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EGX95_27940 ENOG4108SHN Glycosyl transferase, family 2 EGX95_27960 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EGX95_27990 ENOG4105SX7 Transporter EGX95_28020 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) EGX95_28025 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit EGX95_28030 ENOG4105C83 adenylosuccinate lyase EGX95_28040 ENOG4105VR9 phosphoribosylformylglycinamidine synthase EGX95_28065 ENOG4108V3E phosphoribosylglycinamide formyltransferase EGX95_28080 ENOG4105C12 Phosphoribosylglycinamide synthetase EGX95_28110 ENOG4105C4R Atp-dependent dna helicase EGX95_28135 ENOG4108W2Y isochorismatase EGX95_28145 ENOG4108UMI ABC transporter, permease EGX95_28150 ENOG4105D01 (LipO)protein EGX95_28170 ENOG410834F Transcriptional regulator EGX95_28175 ENOG4107I77 yiaA/B two helix domain EGX95_28195 ENOG4105CBD Diacylglycerol kinase EGX95_28200 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase EGX95_28205 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EGX95_28210 ENOG4108JPW Aminotransferase EGX95_28220 ENOG4105C26 Dehydrogenase EGX95_28225 ENOG4105KPY Small multidrug resistance protein EGX95_28240 ENOG4105D9N nucleoside EGX95_28245 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) EGX95_28255 ENOG4105BZU Histidine kinase EGX95_28260 ENOG4105C7K acetolactate synthase EGX95_28270 ENOG4108W15 Protein of unknown function (DUF1456) EGX95_28295 ENOG4105DDC Oxidoreductase domain protein EGX95_28300 ENOG4105CQB FAD linked oxidase domain protein EGX95_28310 ENOG4105CWC Acetylornithine deacetylase EGX95_28335 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EGX95_28345 ENOG4107Y80 Major Facilitator superfamily EGX95_28365 ENOG4108W15 Protein of unknown function (DUF1456) EGX95_28380 ENOG4105DTQ mandelate racemase muconate lactonizing EGX95_28390 ENOG4105DFD Na H antiporter EGX95_28410 ENOG4105D3R alkyl hydroperoxide reductase EGX95_28415 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) EGX95_28425 ENOG4107W7X Aldolase EGX95_28440 ENOG4105EHG Permease protein EGX95_28445 ENOG4105DQ5 transport system permease protein EGX95_28450 ENOG4108V5C ABC transporter EGX95_28475 ENOG4106UIA EGX95_28480 ENOG4106UIA EGX95_28515 ENOG4105D2S major facilitator superfamily EGX95_28540 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase EGX95_28545 ENOG4105E5Q amino acid AbC transporter EGX95_28550 ENOG4105EAB amino acid AbC transporter EGX95_28560 ENOG4105C8Q Methyl-accepting chemotaxis EGX95_28570 ENOG4105CI1 PTS System EGX95_28600 ENOG4107RBB ABC transporter, permease EGX95_28605 ENOG4105C19 ABC transporter EGX95_28630 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) EGX95_28665 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter EGX95_28680 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EGX95_28700 ENOG4105C5H ABC transporter EGX95_28730 ENOG41062JF Transcriptional regulator EGX95_28750 ENOG4105DEU major facilitator superfamily EGX95_28780 ENOG4108N0M stress protein EGX95_28785 ENOG4106FN3 tellurium resistance protein EGX95_28790 ENOG4106FN3 tellurium resistance protein EGX95_28795 ENOG4107TS3 membrane protein, TerC EGX95_28800 ENOG4108TTB tellurium resistance protein EGX95_28820 ENOG4105KJF protein tyrosine phosphatase EGX95_28830 ENOG4107U9T Pfam:Ribonuclease_BN EGX95_28835 ENOG4105C59 p-type ATPase EGX95_28840 ENOG4108IPJ Membrane EGX95_28855 ENOG4105C3F Signal peptidase i EGX95_28865 ENOG4107ZTW SNARE associated Golgi EGX95_28880 ENOG410606W general stress protein EGX95_28885 ENOG4105UPD Calcium Proton EGX95_28935 ENOG4108JUB Transcriptional regulator EGX95_28945 ENOG4108IQI permease EGX95_28975 ENOG4105CSV Glutaminase EGX95_28990 ENOG4108A04 Beta-lactamase EGX95_29005 ENOG4105CKK Glycosyl transferase, family 2 EGX95_29010 ENOG4107QQG Dehydrogenase EGX95_29015 ENOG4105C3I Nad-dependent epimerase dehydratase EGX95_29035 ENOG4105F1A Pyruvate formate-lyase EGX95_29055 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) EGX95_29060 ENOG4105ECP epimerase EGX95_29090 ENOG41067AE Membrane-bound metal-dependent hydrolase EGX95_29095 ENOG4105CEN a g-specific adenine glycosylase EGX95_29100 ENOG4106BXE EGX95_29120 ENOG4105BZ1 (ABC) transporter EGX95_29125 ENOG4107NBY Membrane EGX95_29130 ENOG4105CBC glutamate synthase EGX95_29140 ENOG4108IUW ABC transporter EGX95_29160 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EGX95_29165 ENOG4105G5W regulator Fur family EGX95_29275 ENOG4108JQC penicillin-binding protein 1A EGX95_29280 ENOG4108R9S DSBA oxidoreductase EGX95_29295 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) EGX95_29305 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) EGX95_29315 ENOG4105CYN Serine protein kinase EGX95_29335 ENOG4105C94 Transporter EGX95_29350 ENOG4105DZ6 Band 7 protein EGX95_29360 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism EGX95_29365 ENOG4108V9W transcriptional regulatory protein EGX95_29370 ENOG4105D4T Citrate transporter EGX95_29395 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator EGX95_29400 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EGX95_29405 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component EGX95_29410 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component EGX95_29415 ENOG4105BZ7 extracellular solute-binding protein family 1 EGX95_29420 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) EGX95_29425 ENOG4108STX response regulator EGX95_29430 ENOG4105US7 Histidine kinase EGX95_29450 ENOG4108UZ3 Transporter EGX95_29455 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EGX95_29465 ENOG4105BZU Histidine kinase EGX95_29470 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX95_29475 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) EGX95_29480 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) EGX95_29485 ENOG4108JB9 formate dehydrogenase EGX95_29505 ENOG4105CUB amino acid EGX95_29515 ENOG4105C59 p-type ATPase EGX95_29520 ENOG4105DAP Nicotinate phosphoribosyltransferase EGX95_29550 ENOG41073R8 VanW family EGX95_29555 ENOG4108KGH TRANSCRIPTIONal EGX95_29560 ENOG4105D9N nucleoside EGX95_29565 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase EGX95_29570 ENOG4105C37 (CBS) domain EGX95_29575 ENOG4108IJ0 Aspartate ammonia-lyase EGX95_29580 ENOG4105DAA L-lactate EGX95_29595 ENOG4105DUX Transporter EGX95_29600 ENOG4108MES Periplasmic binding protein EGX95_29605 ENOG4105DQ5 transport system permease protein EGX95_29610 ENOG4108IHU transport system permease protein EGX95_29615 ENOG4105E0A ABC, transporter EGX95_29620 ENOG4105DMQ Methyltransferase EGX95_29630 ENOG4105EXW epimerase dehydratase EGX95_29635 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) EGX95_29645 ENOG4107T89 von Willebrand factor, type A EGX95_29650 ENOG4105GMT ATPase associated with various cellular activities aaa_5 EGX95_29655 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) EGX95_29670 ENOG4105BZU Histidine kinase EGX95_29675 ENOG4105D5Q Arginine ornithine antiporter EGX95_29680 ENOG4107414 GntR family transcriptional regulator EGX95_29685 ENOG4105C5Y PTS System EGX95_29690 ENOG4105CG3 alpha amylase, catalytic region EGX95_29705 ENOG4105E1K spore germination protein EGX95_29710 ENOG4105CRN Aminoglycoside phosphotransferase EGX95_29715 ENOG4105BZG amino acid carrier protein EGX95_29720 ENOG4105CDA abc transporter atp-binding protein EGX95_29725 ENOG4105CT1 (ABC) transporter EGX95_29730 ENOG4105EAD ABC transporter EGX95_29735 ENOG4105DRP amino acid AbC transporter EGX95_29740 ENOG4108IQI permease EGX95_29755 ENOG4105GFR rna polymerase sigma factor EGX95_29765 ENOG4105D29 Helix-turn-helix type 11 domain protein EGX95_29770 ENOG4105NAE bifunctional deaminase-reductase domain protein EGX95_29775 ENOG4105BZU Histidine kinase EGX95_29790 ENOG4105CHH sulfate transporter EGX95_29795 ENOG41068KF Universal stress protein EGX95_29805 ENOG4105DEF Extracellular solute-binding protein, family 5 EGX95_29815 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EGX95_29820 ENOG4108JQ7 (ABC) transporter EGX95_29830 ENOG4105CXY transporter EGX95_29835 ENOG41067TZ transcriptional regulator, MarR family EGX95_29840 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX95_29845 ENOG4105ETE Transcriptional regulator (LacI family EGX95_29850 ENOG4108RVA ribokinase EGX95_29860 ENOG4105C2J ABC transporter EGX95_29865 ENOG4105CNN ABC, transporter EGX95_29870 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator EGX95_29875 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EGX95_29935 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer EGX95_29940 ENOG41069ER domain protein