locus-tag	class	description
GPA07_00010	COG2186	Transcriptional regulator
GPA07_00040	COG0726	polysaccharide deacetylase
GPA07_00045	COG2194	sulfuric ester hydrolase activity
GPA07_00055	COG0489	protein tyrosine kinase activity
GPA07_00060	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPA07_00095	COG2814	Major facilitator Superfamily
GPA07_00145	COG1674	ftsk spoiiie
GPA07_00165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GPA07_00170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPA07_00175	COG0101	tRNA pseudouridine synthase activity
GPA07_00180	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPA07_00185	COG1122	ATPase activity
GPA07_00190	COG1122	ATPase activity
GPA07_00195	COG0203	ribosomal protein L17
GPA07_00200	COG0202	RNA polymerase activity
GPA07_00205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPA07_00210	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPA07_00215	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GPA07_00220	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPA07_00225	COG0024	Methionine aminopeptidase
GPA07_00230	COG0563	adenylate kinase activity
GPA07_00235	COG0201	protein transport
GPA07_00240	COG0200	Binds to the 23S rRNA
GPA07_00245	COG1841	ribosomal large subunit assembly
GPA07_00250	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPA07_00255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPA07_00260	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPA07_00265	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPA07_00270	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPA07_00275	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPA07_00280	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPA07_00285	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPA07_00290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPA07_00295	COG0255	Belongs to the universal ribosomal protein uL29 family
GPA07_00300	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPA07_00305	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPA07_00310	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPA07_00315	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPA07_00320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPA07_00325	COG0089	rRNA binding
GPA07_00330	COG0088	Forms part of the polypeptide exit tunnel
GPA07_00335	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPA07_00340	COG0051	transcription antitermination factor activity, RNA binding
GPA07_00345	COG0596	Alpha beta hydrolase
GPA07_00350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPA07_00355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPA07_00360	COG0049	tRNA binding
GPA07_00365	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPA07_00370	COG1358	cellular component organization or biogenesis
GPA07_00375	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPA07_00380	COG0085	RNA polymerase activity
GPA07_00385	COG2813	Specifically methylates the guanine in position
GPA07_00390	COG0222	ribosome binding
GPA07_00395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPA07_00400	COG0081	regulation of translation
GPA07_00405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPA07_00410	COG0250	Participates in transcription elongation, termination and antitermination
GPA07_00415	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPA07_00420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPA07_00425	COG1595	DNA-templated transcription, initiation
GPA07_00430	COG3688	RNA-binding protein containing a PIN domain
GPA07_00435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPA07_00440	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GPA07_00445	COG0215	cysteine-tRNA ligase activity
GPA07_00450	COG1045	serine acetyltransferase
GPA07_00455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPA07_00460	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GPA07_00465	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPA07_00470	COG4956	integral membrane protein (PIN domain superfamily)
GPA07_00475	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GPA07_00480	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPA07_00485	COG0542	response to heat
GPA07_00490	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GPA07_00495	COG3880	PFAM UvrB UvrC protein
GPA07_00500	COG4463	regulation of RNA biosynthetic process
GPA07_00580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPA07_00585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPA07_00590	COG1396	sequence-specific DNA binding
GPA07_00595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPA07_00600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPA07_00605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPA07_00610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPA07_00615	COG0512	Glutamine amidotransferase of anthranilate synthase
GPA07_00620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPA07_00625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPA07_00630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPA07_00635	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPA07_00640	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GPA07_00645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPA07_00655	COG0037	tRNA processing
GPA07_00660	COG0515	serine threonine protein kinase
GPA07_00665	COG2304	oxidoreductase activity
GPA07_00670	COG2208	phosphoserine phosphatase activity
GPA07_00685	COG1098	S1 RNA binding domain
GPA07_00690	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPA07_00705	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPA07_00710	COG3956	TIGRFAM MazG family protein
GPA07_00715	COG2244	polysaccharide biosynthetic process
GPA07_00720	COG2002	toxin-antitoxin pair type II binding
GPA07_00725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPA07_00735	COG0193	aminoacyl-tRNA hydrolase activity
GPA07_00740	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPA07_00745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPA07_00750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPA07_00755	COG2088	sporulation resulting in formation of a cellular spore
GPA07_00760	COG0251	oxidation-reduction process
GPA07_00765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPA07_00770	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPA07_00780	COG4466	Protein conserved in bacteria
GPA07_00790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GPA07_00795	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPA07_00800	COG3583	domain protein
GPA07_00800	COG3584	3D domain protein
GPA07_00805	COG0084	hydrolase, TatD family'
GPA07_00810	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPA07_00810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPA07_00815	COG2002	toxin-antitoxin pair type II binding
GPA07_00820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPA07_00825	COG2827	Endonuclease containing a URI domain
GPA07_00830	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPA07_00835	COG4467	Involved in initiation control of chromosome replication
GPA07_00840	COG1774	PSP1 C-terminal conserved region
GPA07_00845	COG0470	DNA polymerase III
GPA07_00850	COG1728	Protein conserved in bacteria
GPA07_00855	COG3870	Protein conserved in bacteria
GPA07_00860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPA07_00865	COG1982	Orn Lys Arg decarboxylase major
GPA07_00870	COG3853	Toxic anion resistance protein (TelA)
GPA07_00875	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GPA07_00920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPA07_00925	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPA07_00930	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPA07_00940	COG0590	tRNA wobble adenosine to inosine editing
GPA07_00945	COG1335	isochorismatase
GPA07_00950	COG3858	chitin binding
GPA07_00950	COG1388	LysM domain
GPA07_00955	COG1428	Deoxynucleoside kinase
GPA07_00960	COG1428	Deoxynucleoside kinase
GPA07_00980	COG1847	R3H domain protein
GPA07_00985	COG2208	phosphoserine phosphatase activity
GPA07_01010	COG0300	oxidoreductase activity
GPA07_01025	COG0840	transmembrane signaling receptor activity
GPA07_01030	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPA07_01035	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GPA07_01040	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GPA07_01045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPA07_01055	COG1686	Belongs to the peptidase S11 family
GPA07_01060	COG0517	IMP dehydrogenase activity
GPA07_01060	COG0516	GMP reductase activity
GPA07_01095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPA07_01100	COG0187	DNA topoisomerase II activity
GPA07_01110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPA07_01115	COG2501	S4 domain
GPA07_01120	COG0592	DNA-directed DNA polymerase activity
GPA07_01125	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPA07_01130	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GPA07_01135	COG0594	ribonuclease P activity
GPA07_01140	COG0706	membrane insertase activity
GPA07_01145	COG1847	R3H domain protein
GPA07_01150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPA07_01155	COG0445	tRNA wobble uridine modification
GPA07_01160	COG0357	Ribosomal RNA small subunit methyltransferase G
GPA07_01165	COG1475	DNA binding
GPA07_01175	COG1192	Involved in chromosome partitioning
GPA07_01180	COG1475	DNA binding
GPA07_01190	COG3949	Membrane
GPA07_01205	COG4481	Protein conserved in bacteria
GPA07_01210	COG0012	GTP binding
GPA07_01215	COG0360	Binds together with S18 to 16S ribosomal RNA
GPA07_01220	COG0629	single-stranded DNA binding
GPA07_01225	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPA07_01230	COG0346	lactoylglutathione lyase activity
GPA07_01235	COG0400	carboxylic ester hydrolase activity
GPA07_01240	COG0655	NAD(P)H dehydrogenase (quinone) activity
GPA07_01250	COG0753	catalase activity
GPA07_01260	COG1595	DNA-templated transcription, initiation
GPA07_01270	COG1227	inorganic diphosphatase activity
GPA07_01275	COG4241	membrane
GPA07_01280	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GPA07_01285	COG0359	binds to the 23S rRNA
GPA07_01290	COG2807	transmembrane transport
GPA07_01295	COG3093	addiction module antidote protein HigA
GPA07_01300	COG0454	-acetyltransferase
GPA07_01315	COG0305	Participates in initiation and elongation during chromosome replication
GPA07_01320	COG0346	lactoylglutathione lyase activity
GPA07_01325	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPA07_01330	COG2311	Membrane
GPA07_01365	COG0745	RESPONSE REGULATOR receiver
GPA07_01370	COG5002	protein histidine kinase activity
GPA07_01375	COG4863	YycH protein
GPA07_01380	COG4853	Protein conserved in bacteria
GPA07_01385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GPA07_01390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPA07_01395	COG0456	acetyltransferase
GPA07_01420	COG4720	Psort location CytoplasmicMembrane, score
GPA07_01430	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPA07_01440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPA07_01450	COG0210	DNA helicase
GPA07_01475	COG0583	DNA-binding transcription factor activity
GPA07_01480	COG0384	phenazine biosynthesis protein PhzF
GPA07_01490	COG2188	Transcriptional regulator
GPA07_01495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA07_01495	COG2190	(PTS) system
GPA07_01495	COG1263	PTS System
GPA07_01500	COG2723	6-phospho-beta-galactosidase activity
GPA07_01510	COG5444	nuclease activity
GPA07_01530	COG2814	Major facilitator Superfamily
GPA07_01535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPA07_01540	COG2814	Major facilitator Superfamily
GPA07_01550	COG1113	amino acid transport
GPA07_01565	COG0494	nUDIX hydrolase
GPA07_01580	COG0457	Tetratricopeptide repeat
GPA07_01585	COG1136	(ABC) transporter
GPA07_01595	COG2814	Major facilitator Superfamily
GPA07_01600	COG1309	transcriptional regulator
GPA07_01610	COG1929	Belongs to the glycerate kinase type-1 family
GPA07_01615	COG2824	Alkylphosphonate utilization operon protein PhnA
GPA07_01620	COG1131	(ABC) transporter
GPA07_01625	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GPA07_01635	COG2851	Citrate transporter
GPA07_01640	COG1874	Beta-galactosidase
GPA07_01650	COG3833	ABC-type maltose transport systems, permease component
GPA07_01655	COG1175	transmembrane transport
GPA07_01670	COG0583	DNA-binding transcription factor activity
GPA07_01700	COG1737	Transcriptional regulator
GPA07_01705	COG1070	Carbohydrate kinase
GPA07_01715	COG4335	DNA alkylation repair
GPA07_01720	COG1113	amino acid transport
GPA07_01730	COG0673	inositol 2-dehydrogenase activity
GPA07_01735	COG0789	Transcriptional regulator
GPA07_01740	COG0561	phosphatase activity
GPA07_01750	COG2226	methyltransferase
GPA07_01765	COG2390	Transcriptional regulator
GPA07_01770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPA07_01775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPA07_01780	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPA07_01795	COG1846	Transcriptional regulator
GPA07_01800	COG0778	Nitroreductase
GPA07_01805	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GPA07_01810	COG4412	M6 family metalloprotease domain protein
GPA07_01810	COG3291	Pkd domain containing protein
GPA07_01835	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPA07_01840	COG4721	ABC-type cobalt transport system, permease component
GPA07_01845	COG1122	ATPase activity
GPA07_01850	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPA07_01860	COG3878	Protein conserved in bacteria
GPA07_01865	COG3711	transcriptional antiterminator
GPA07_01870	COG2190	(PTS) system
GPA07_01870	COG1263	PTS System
GPA07_01870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA07_01875	COG2723	6-phospho-beta-galactosidase activity
GPA07_01895	COG1136	(ABC) transporter
GPA07_01910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPA07_01915	COG2610	gluconate transmembrane transporter activity
GPA07_01925	COG2084	Dehydrogenase
GPA07_01930	COG1737	Transcriptional regulator
GPA07_01945	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPA07_01950	COG4842	Belongs to the WXG100 family
GPA07_01975	COG1396	sequence-specific DNA binding
GPA07_01980	COG0252	asparaginase activity
GPA07_01985	COG1027	Aspartate ammonia-lyase
GPA07_01990	COG1757	Na H antiporter
GPA07_02015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA07_02015	COG3711	transcriptional antiterminator
GPA07_02020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA07_02025	COG1312	Catalyzes the dehydration of D-mannonate
GPA07_02030	COG2723	6-phospho-beta-galactosidase activity
GPA07_02035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA07_02040	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPA07_02045	COG0726	polysaccharide deacetylase
GPA07_02055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPA07_02055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPA07_02060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPA07_02060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPA07_02065	COG2514	catechol 2,3-dioxygenase activity
GPA07_02070	COG1733	regulation of RNA biosynthetic process
GPA07_02075	COG5386	Cell surface protein
GPA07_02080	COG5386	Cell surface protein
GPA07_02105	COG4509	Sortase family
GPA07_02115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA07_02125	COG1271	oxidase subunit
GPA07_02130	COG1294	oxidase, subunit
GPA07_02135	COG4988	ABC transporter
GPA07_02140	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPA07_02145	COG3866	Pectate lyase
GPA07_02150	COG1595	DNA-templated transcription, initiation
GPA07_02165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GPA07_02170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA07_02170	COG3711	transcriptional antiterminator
GPA07_02175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA07_02180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA07_02185	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPA07_02190	COG1486	melibiose metabolic process
GPA07_02200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPA07_02205	COG3420	alginic acid biosynthetic process
GPA07_02215	COG0745	RESPONSE REGULATOR receiver
GPA07_02230	COG1129	ABC transporter
GPA07_02235	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPA07_02240	COG2357	RelA SpoT domain protein
GPA07_02245	COG0457	Tetratricopeptide repeat
GPA07_02250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA07_02255	COG0765	amino acid transport
GPA07_02265	COG0346	lactoylglutathione lyase activity
GPA07_02270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPA07_02275	COG1346	cytolysis
GPA07_02280	COG1380	Effector of murein hydrolase LrgA
GPA07_02285	COG0583	DNA-binding transcription factor activity
GPA07_02290	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPA07_02295	COG0352	thiamine-phosphate diphosphorylase activity
GPA07_02310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPA07_02315	COG3162	membrane
GPA07_02335	COG2246	polysaccharide biosynthetic process
GPA07_02350	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPA07_02355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPA07_02360	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GPA07_02370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPA07_02375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPA07_02380	COG1845	cytochrome c oxidase, subunit III
GPA07_02385	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GPA07_02395	COG0772	Belongs to the SEDS family
GPA07_02400	COG0778	Nitroreductase
GPA07_02405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPA07_02415	COG1404	Belongs to the peptidase S8 family
GPA07_02425	COG3711	transcriptional antiterminator
GPA07_02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA07_02430	COG1263	PTS System
GPA07_02435	COG1621	beta-fructofuranosidase activity
GPA07_02450	COG0351	phosphomethylpyrimidine kinase
GPA07_02460	COG1216	Glycosyl transferase, family 2
GPA07_02465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPA07_02470	COG1012	belongs to the aldehyde dehydrogenase family
GPA07_02480	COG2233	PERMEase
GPA07_02485	COG2363	Small membrane protein
GPA07_02505	COG0463	Glycosyl transferase, family 2
GPA07_02510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPA07_02515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPA07_02520	COG0456	acetyltransferase
GPA07_02525	COG2089	acid synthase
GPA07_02530	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GPA07_02535	COG3980	spore coat polysaccharide biosynthesis protein
GPA07_02540	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPA07_02545	COG1088	dTDP-glucose 4,6-dehydratase activity
GPA07_02550	COG1091	dTDP-4-dehydrorhamnose reductase activity
GPA07_02555	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GPA07_02560	COG2814	Major facilitator Superfamily
GPA07_02565	COG1522	sequence-specific DNA binding
GPA07_02570	COG2814	Major facilitator Superfamily
GPA07_02580	COG0280	phosphate acetyltransferase
GPA07_02595	COG5444	nuclease activity
GPA07_02645	COG4844	belongs to the
GPA07_02650	COG1078	dGTPase activity
GPA07_02655	COG3465	dGTPase activity
GPA07_02660	COG1126	abc transporter atp-binding protein
GPA07_02665	COG0765	amino acid transport
GPA07_02675	COG0765	amino acid transport
GPA07_02680	COG0454	-acetyltransferase
GPA07_02685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPA07_02690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPA07_02695	COG0431	NADPH-dependent FMN reductase
GPA07_02700	COG0583	DNA-binding transcription factor activity
GPA07_02705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPA07_02715	COG1942	4-Oxalocrotonate Tautomerase
GPA07_02720	COG1994	Peptidase M50
GPA07_02730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPA07_02735	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GPA07_02740	COG0010	Belongs to the arginase family
GPA07_02745	COG4506	Protein conserved in bacteria
GPA07_02750	COG0018	arginyl-trna synthetase
GPA07_02760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPA07_02765	COG1132	(ABC) transporter
GPA07_02775	COG1619	proteins homologs of microcin C7 resistance protein MccF
GPA07_02785	COG4294	response to UV
GPA07_02790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPA07_02795	COG0247	lactate metabolic process
GPA07_02795	COG2181	nitrate reductase activity
GPA07_02800	COG0183	Belongs to the thiolase family
GPA07_02805	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPA07_02810	COG1960	acyl-CoA dehydrogenase activity
GPA07_02815	COG1960	acyl-CoA dehydrogenase activity
GPA07_02820	COG3343	RNA polymerase activity
GPA07_02825	COG0504	CTP synthase activity
GPA07_02830	COG4821	SIS domain
GPA07_02835	COG2204	response regulator
GPA07_02840	COG0191	fructose-bisphosphate aldolase activity
GPA07_02845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPA07_02850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPA07_02855	COG1494	fructose-1,6-bisphosphatase
GPA07_02860	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPA07_02865	COG0254	rRNA binding
GPA07_02870	COG1435	thymidine kinase activity
GPA07_02875	COG0281	malic enzyme
GPA07_02880	COG0679	Auxin Efflux Carrier
GPA07_02885	COG0789	Transcriptional regulator
GPA07_02890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPA07_02895	COG2890	protein-(glutamine-N5) methyltransferase activity
GPA07_02910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPA07_02915	COG0009	L-threonylcarbamoyladenylate synthase
GPA07_02920	COG1971	Probably functions as a manganese efflux pump
GPA07_02925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPA07_02930	COG0698	ribose 5-phosphate isomerase
GPA07_02935	COG4475	Protein of unknown function (DUF436)
GPA07_02940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPA07_02945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPA07_02955	COG0356	it plays a direct role in the translocation of protons across the membrane
GPA07_02960	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPA07_02965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPA07_02970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPA07_02975	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPA07_02980	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPA07_02985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPA07_02990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPA07_03000	COG4836	Membrane
GPA07_03010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPA07_03015	COG2385	sporulation resulting in formation of a cellular spore
GPA07_03020	COG2304	oxidoreductase activity
GPA07_03025	COG2304	oxidoreductase activity
GPA07_03030	COG0243	molybdopterin cofactor binding
GPA07_03040	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPA07_03045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPA07_03050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPA07_03055	COG0523	cobalamin synthesis protein
GPA07_03060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPA07_03095	COG1247	-acetyltransferase
GPA07_03100	COG0739	heme binding
GPA07_03105	COG0347	Belongs to the P(II) protein family
GPA07_03110	COG0004	ammonium transporteR
GPA07_03115	COG1126	abc transporter atp-binding protein
GPA07_03125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA07_03130	COG0477	Major facilitator Superfamily
GPA07_03135	COG0671	phosphoesterase, PA-phosphatase related
GPA07_03140	COG2814	Major facilitator Superfamily
GPA07_03145	COG1846	Transcriptional regulator
GPA07_03150	COG1609	Transcriptional regulator
GPA07_03155	COG1077	Cell shape determining protein MreB Mrl
GPA07_03160	COG4786	Flagellar basal body rod
GPA07_03165	COG4786	Flagellar basal body rod
GPA07_03170	COG0457	Tetratricopeptide repeat
GPA07_03175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPA07_03180	COG1970	mechanosensitive ion channel activity
GPA07_03195	COG0561	phosphatase activity
GPA07_03200	COG1366	Belongs to the anti-sigma-factor antagonist family
GPA07_03200	COG2202	Pas domain
GPA07_03205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPA07_03210	COG4715	Zinc finger, swim domain protein
GPA07_03215	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPA07_03220	COG2059	Chromate
GPA07_03225	COG2059	Chromate
GPA07_03230	COG1522	sequence-specific DNA binding
GPA07_03235	COG3527	Alpha-acetolactate decarboxylase
GPA07_03240	COG0028	Belongs to the TPP enzyme family
GPA07_03245	COG0583	DNA-binding transcription factor activity
GPA07_03250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GPA07_03255	COG1879	ABC-type sugar transport system periplasmic component
GPA07_03260	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPA07_03265	COG1129	ABC transporter
GPA07_03270	COG1869	D-ribose catabolic process
GPA07_03275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPA07_03280	COG1609	Transcriptional regulator
GPA07_03295	COG0697	spore germination
GPA07_03300	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPA07_03310	COG2843	Capsule synthesis protein
GPA07_03315	COG0791	NLP P60 protein
GPA07_03320	COG0561	phosphatase activity
GPA07_03325	COG1316	TRANSCRIPTIONal
GPA07_03330	COG2814	Major facilitator Superfamily
GPA07_03335	COG1216	Glycosyl transferase, family 2
GPA07_03345	COG0814	amino acid
GPA07_03350	COG0697	spore germination
GPA07_03355	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_03360	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GPA07_03370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPA07_03375	COG0800	Aldolase
GPA07_03380	COG0454	-acetyltransferase
GPA07_03390	COG2972	Histidine kinase
GPA07_03395	COG2197	response regulator
GPA07_03400	COG1653	transport
GPA07_03405	COG1175	transmembrane transport
GPA07_03415	COG1482	cell wall glycoprotein biosynthetic process
GPA07_03420	COG4193	domain, Protein
GPA07_03425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPA07_03430	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GPA07_03435	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GPA07_03445	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPA07_03450	COG1682	transport, permease protein
GPA07_03455	COG1134	teichoic acid transport
GPA07_03460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GPA07_03465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GPA07_03470	COG1316	TRANSCRIPTIONal
GPA07_03480	COG2247	cell wall binding repeat
GPA07_03480	COG2385	sporulation resulting in formation of a cellular spore
GPA07_03485	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPA07_03485	COG2247	cell wall binding repeat
GPA07_03505	COG2244	polysaccharide biosynthetic process
GPA07_03515	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPA07_03520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPA07_03525	COG3307	-O-antigen
GPA07_03530	COG3206	protein involved in exopolysaccharide biosynthesis
GPA07_03535	COG1215	transferase activity, transferring glycosyl groups
GPA07_03540	COG0438	transferase activity, transferring glycosyl groups
GPA07_03545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPA07_03555	COG1316	TRANSCRIPTIONal
GPA07_03560	COG1739	Uncharacterized protein family UPF0029
GPA07_03565	COG4585	Histidine kinase
GPA07_03570	COG2197	response regulator
GPA07_03575	COG1307	EDD domain protein, DegV family
GPA07_03580	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GPA07_03590	COG1040	competence protein
GPA07_03605	COG3418	PFAM FlgN family protein
GPA07_03610	COG4786	Flagellar basal body rod
GPA07_03610	COG1256	bacterial-type flagellum assembly
GPA07_03615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPA07_03625	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GPA07_03630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GPA07_03635	COG1334	flagellar protein FlaG
GPA07_03640	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPA07_03645	COG1516	flagellar protein fliS
GPA07_03660	COG0840	transmembrane signaling receptor activity
GPA07_03665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPA07_03675	COG0653	protein targeting
GPA07_03695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPA07_03700	COG2010	Cytochrome c
GPA07_03705	COG2884	Cell division ATP-binding protein ftsE
GPA07_03710	COG2177	Part of the ABC transporter FtsEX involved in
GPA07_03715	COG0791	NLP P60 protein
GPA07_03715	COG3883	PFAM NLP P60 protein
GPA07_03720	COG0730	response to heat
GPA07_03725	COG3409	Peptidoglycan-binding domain 1 protein
GPA07_03725	COG0793	Belongs to the peptidase S41A family
GPA07_03735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPA07_03740	COG3866	Pectate lyase
GPA07_03745	COG0778	Nitroreductase
GPA07_03750	COG1113	amino acid transport
GPA07_03755	COG0463	Glycosyl transferase, family 2
GPA07_03760	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPA07_03765	COG5002	protein histidine kinase activity
GPA07_03770	COG0745	RESPONSE REGULATOR receiver
GPA07_03780	COG2814	Major facilitator Superfamily
GPA07_03785	COG1309	transcriptional regulator
GPA07_03790	COG0574	Belongs to the PEP-utilizing enzyme family
GPA07_03790	COG3848	Pyruvate phosphate dikinase
GPA07_03795	COG4897	Protein conserved in bacteria
GPA07_03805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPA07_03820	COG3595	metallopeptidase activity
GPA07_03825	COG1983	PspC domain protein
GPA07_03830	COG1950	PFAM Membrane protein of
GPA07_03835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GPA07_03845	COG0363	glucosamine-6-phosphate deaminase activity
GPA07_03850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPA07_03855	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GPA07_03860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPA07_03865	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GPA07_03870	COG0546	phosphoglycolate phosphatase activity
GPA07_03875	COG0110	maltose O-acetyltransferase activity
GPA07_03880	COG1959	2 iron, 2 sulfur cluster binding
GPA07_03885	COG2910	NAD(P)H-binding
GPA07_03890	COG4990	cell redox homeostasis
GPA07_03895	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GPA07_03900	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GPA07_03905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPA07_03910	COG0131	Imidazoleglycerol-phosphate dehydratase
GPA07_03915	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPA07_03920	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPA07_03925	COG0107	imidazoleglycerol-phosphate synthase activity
GPA07_03930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPA07_03930	COG0140	phosphoribosyl-ATP diphosphatase activity
GPA07_03935	COG0457	Tetratricopeptide repeat
GPA07_03940	COG0791	NLP P60 protein
GPA07_03940	COG3883	PFAM NLP P60 protein
GPA07_03945	COG0492	ferredoxin-NADP+ reductase activity
GPA07_03950	COG1051	belongs to the nudix hydrolase family
GPA07_03955	COG1660	Displays ATPase and GTPase activities
GPA07_03960	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPA07_03965	COG1481	regulation of sporulation
GPA07_03970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA07_03975	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GPA07_03985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPA07_03995	COG1694	Mazg nucleotide pyrophosphohydrolase
GPA07_04005	COG0740	serine-type endopeptidase activity
GPA07_04035	COG1819	glycosyl
GPA07_04040	COG0747	negative chemotaxis
GPA07_04045	COG0601	transmembrane transport
GPA07_04050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPA07_04060	COG1124	(ABC) transporter
GPA07_04065	COG0726	polysaccharide deacetylase
GPA07_04070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA07_04075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA07_04080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPA07_04090	COG1396	sequence-specific DNA binding
GPA07_04095	COG3944	biosynthesis protein
GPA07_04100	COG0489	protein tyrosine kinase activity
GPA07_04105	COG1086	Polysaccharide biosynthesis protein
GPA07_04110	COG0438	transferase activity, transferring glycosyl groups
GPA07_04115	COG1215	transferase activity, transferring glycosyl groups
GPA07_04120	COG0438	transferase activity, transferring glycosyl groups
GPA07_04130	COG1216	Glycosyl transferase, family 2
GPA07_04135	COG5039	Polysaccharide pyruvyl transferase
GPA07_04140	COG2244	polysaccharide biosynthetic process
GPA07_04145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPA07_04150	COG0110	maltose O-acetyltransferase activity
GPA07_04155	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPA07_04165	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GPA07_04170	COG2186	Transcriptional regulator
GPA07_04175	COG3829	transcription factor binding
GPA07_04180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPA07_04185	COG0833	amino acid
GPA07_04190	COG2390	Transcriptional regulator
GPA07_04195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPA07_04200	COG0126	phosphoglycerate kinase activity
GPA07_04205	COG0149	triose-phosphate isomerase activity
GPA07_04210	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPA07_04215	COG0148	phosphopyruvate hydratase activity
GPA07_04225	COG1131	(ABC) transporter
GPA07_04245	COG0456	acetyltransferase
GPA07_04250	COG2095	MarC family integral membrane protein
GPA07_04255	COG1510	regulation of RNA biosynthetic process
GPA07_04260	COG0517	IMP dehydrogenase activity
GPA07_04260	COG1125	glycine betaine transport
GPA07_04265	COG1174	glycine betaine transport
GPA07_04270	COG1732	Glycine betaine
GPA07_04275	COG1174	glycine betaine transport
GPA07_04280	COG1733	regulation of RNA biosynthetic process
GPA07_04285	COG1396	sequence-specific DNA binding
GPA07_04290	COG1396	sequence-specific DNA binding
GPA07_04295	COG1476	TRANSCRIPTIONal
GPA07_04300	COG2002	toxin-antitoxin pair type II binding
GPA07_04305	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPA07_04310	COG1647	Serine aminopeptidase, S33
GPA07_04315	COG0557	exoribonuclease II activity
GPA07_04320	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPA07_04345	COG0745	RESPONSE REGULATOR receiver
GPA07_04345	COG3706	GGDEF domain
GPA07_04355	COG1937	Protein conserved in bacteria
GPA07_04360	COG2608	mercury ion transmembrane transporter activity
GPA07_04365	COG2217	Heavy metal translocating P-type atpase
GPA07_04380	COG1027	Aspartate ammonia-lyase
GPA07_04385	COG4191	Histidine kinase
GPA07_04390	COG0784	Response regulator, receiver
GPA07_04400	COG0803	Belongs to the bacterial solute-binding protein 9 family
GPA07_04405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPA07_04410	COG1121	(ABC) transporter
GPA07_04415	COG2217	Heavy metal translocating P-type atpase
GPA07_04420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPA07_04425	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GPA07_04430	COG2860	membrane
GPA07_04435	COG0025	NhaP-type Na H and K H
GPA07_04440	COG1940	carbohydrate kinase activity
GPA07_04445	COG0656	L-ascorbic acid biosynthetic process
GPA07_04465	COG4149	molybdate abc transporter
GPA07_04470	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPA07_04475	COG1368	sulfuric ester hydrolase activity
GPA07_04480	COG1988	membrane-bound metal-dependent
GPA07_04495	COG0531	amino acid
GPA07_04500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPA07_04505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA07_04510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA07_04515	COG1120	ATPase activity
GPA07_04520	COG0745	RESPONSE REGULATOR receiver
GPA07_04525	COG2205	protein histidine kinase activity
GPA07_04530	COG1904	glucuronate isomerase
GPA07_04535	COG1609	Transcriptional regulator
GPA07_04540	COG0246	Mannitol dehydrogenase
GPA07_04545	COG2721	sulfolactate sulfo-lyase activity
GPA07_04555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPA07_04560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA07_04565	COG1120	ATPase activity
GPA07_04570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPA07_04575	COG1454	alcohol dehydrogenase
GPA07_04590	COG2204	response regulator
GPA07_04600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPA07_04605	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_04610	COG2096	Adenosyltransferase
GPA07_04615	COG4758	membrane
GPA07_04620	COG1842	Phage shock protein A
GPA07_04630	COG4758	membrane
GPA07_04635	COG4585	Histidine kinase
GPA07_04640	COG2197	response regulator
GPA07_04655	COG0814	amino acid
GPA07_04660	COG0697	spore germination
GPA07_04670	COG0114	fumarate hydratase activity
GPA07_04675	COG1309	transcriptional regulator
GPA07_04680	COG2770	Histidine kinase
GPA07_04680	COG2205	protein histidine kinase activity
GPA07_04685	COG0745	RESPONSE REGULATOR receiver
GPA07_04690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPA07_04695	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_04705	COG1120	ATPase activity
GPA07_04715	COG5577	PFAM Coat F domain
GPA07_04730	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPA07_04730	COG1024	Enoyl-CoA hydratase
GPA07_04735	COG0183	Belongs to the thiolase family
GPA07_04740	COG1960	acyl-CoA dehydrogenase activity
GPA07_04745	COG1393	Belongs to the ArsC family
GPA07_04750	COG0509	glycine decarboxylation via glycine cleavage system
GPA07_04760	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPA07_04765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPA07_04775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPA07_04780	COG2011	ABC-type metal ion transport system permease component
GPA07_04785	COG1464	Belongs to the NlpA lipoprotein family
GPA07_04790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPA07_04795	COG0396	ATPase activity
GPA07_04800	COG0719	Fe-S assembly protein
GPA07_04805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPA07_04810	COG0822	iron-sulfur transferase activity
GPA07_04815	COG0719	Fe-S assembly protein
GPA07_04855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPA07_04860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA07_04865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA07_04875	COG2356	endonuclease I
GPA07_04880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPA07_04885	COG2814	Major facilitator Superfamily
GPA07_04890	COG2140	Oxalate decarboxylase
GPA07_04895	COG2508	Transcriptional regulator
GPA07_04900	COG1801	Protein of unknown function DUF72
GPA07_04905	COG0737	Belongs to the 5'-nucleotidase family
GPA07_04910	COG3377	Domain of unknown function (DUF1805)
GPA07_04925	COG0739	heme binding
GPA07_04935	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPA07_04945	COG4470	Protein conserved in bacteria
GPA07_04950	COG2445	Protein of unknown function DUF86
GPA07_04955	COG0647	UMP catabolic process
GPA07_04960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPA07_04965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPA07_04970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPA07_04975	COG0460	homoserine dehydrogenase
GPA07_04980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPA07_04985	COG0083	homoserine kinase activity
GPA07_04990	COG4946	Tricorn protease homolog
GPA07_04990	COG1506	peptidase
GPA07_04990	COG0823	Involved in the tonB-independent uptake of proteins
GPA07_04995	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPA07_05000	COG4837	Protein of unknown function (DUF1462)
GPA07_05010	COG1252	NADH dehydrogenase
GPA07_05015	COG4844	belongs to the
GPA07_05020	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPA07_05025	COG0316	Belongs to the HesB IscA family
GPA07_05045	COG5504	Zn-dependent protease
GPA07_05050	COG0789	Transcriptional regulator
GPA07_05065	COG0492	ferredoxin-NADP+ reductase activity
GPA07_05070	COG1252	NADH dehydrogenase
GPA07_05080	COG3584	3D domain protein
GPA07_05085	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GPA07_05090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPA07_05095	COG2056	Na+-H+ antiporter family
GPA07_05100	COG1268	BioY protein
GPA07_05105	COG0686	Belongs to the AlaDH PNT family
GPA07_05110	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GPA07_05110	COG2508	Transcriptional regulator
GPA07_05115	COG4842	Belongs to the WXG100 family
GPA07_05120	COG5417	Belongs to the EsaB family
GPA07_05125	COG4499	WXG100 protein secretion system (Wss), protein YukC
GPA07_05130	COG1674	ftsk spoiiie
GPA07_05130	COG0433	COG0433 Predicted ATPase
GPA07_05135	COG1511	domain protein
GPA07_05145	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_05150	COG1418	mRNA catabolic process
GPA07_05165	COG0628	permease
GPA07_05185	COG5506	Protein of unknown function (DUF1694)
GPA07_05190	COG1335	isochorismatase
GPA07_05195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPA07_05200	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPA07_05215	COG0142	geranyltranstransferase activity
GPA07_05225	COG4585	Histidine kinase
GPA07_05230	COG2197	response regulator
GPA07_05235	COG2050	protein possibly involved in aromatic compounds catabolism
GPA07_05240	COG1320	monovalent cation:proton antiporter activity
GPA07_05245	COG2212	antiporter activity
GPA07_05250	COG1863	multisubunit Na H antiporter MnhE subunit
GPA07_05255	COG0651	ATP synthesis coupled electron transport
GPA07_05260	COG1006	Multisubunit Na H antiporter MnhC subunit
GPA07_05265	COG2111	Na H antiporter
GPA07_05270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPA07_05270	COG2111	Na H antiporter
GPA07_05280	COG3493	citrate carrier protein
GPA07_05305	COG4565	transcriptional regulatory protein
GPA07_05310	COG3290	protein histidine kinase activity
GPA07_05320	COG3011	Protein conserved in bacteria
GPA07_05325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPA07_05330	COG2814	Major facilitator Superfamily
GPA07_05335	COG5018	Exonuclease
GPA07_05350	COG2205	protein histidine kinase activity
GPA07_05355	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GPA07_05365	COG2267	carboxylic ester hydrolase activity
GPA07_05370	COG1522	sequence-specific DNA binding
GPA07_05375	COG0436	Aminotransferase
GPA07_05380	COG1098	S1 RNA binding domain
GPA07_05385	COG2155	Conserved Protein
GPA07_05390	COG1979	alcohol dehydrogenase
GPA07_05395	COG1979	alcohol dehydrogenase
GPA07_05400	COG0166	Belongs to the GPI family
GPA07_05415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPA07_05425	COG2738	Putative neutral zinc metallopeptidase
GPA07_05430	COG1253	flavin adenine dinucleotide binding
GPA07_05435	COG0432	Pfam Uncharacterised protein family UPF0047
GPA07_05440	COG2070	2-Nitropropane dioxygenase
GPA07_05455	COG0840	transmembrane signaling receptor activity
GPA07_05460	COG0840	transmembrane signaling receptor activity
GPA07_05465	COG0840	transmembrane signaling receptor activity
GPA07_05470	COG0840	transmembrane signaling receptor activity
GPA07_05475	COG0693	protein deglycase activity
GPA07_05480	COG0673	inositol 2-dehydrogenase activity
GPA07_05490	COG0628	permease
GPA07_05495	COG1968	undecaprenyl-diphosphatase activity
GPA07_05505	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPA07_05510	COG1396	sequence-specific DNA binding
GPA07_05520	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GPA07_05530	COG1595	DNA-templated transcription, initiation
GPA07_05535	COG5484	DNA packaging
GPA07_05540	COG1783	phage Terminase large subunit
GPA07_05545	COG5518	Phage portal protein
GPA07_05550	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPA07_05555	COG4653	Phage capsid family
GPA07_05610	COG3953	SLT domain
GPA07_05610	COG5280	Phage tail tape measure protein TP901
GPA07_05610	COG3953	SLT domain
GPA07_05610	COG5280	Phage tail tape measure protein TP901
GPA07_05615	COG1652	LysM domain
GPA07_05620	COG4193	domain, Protein
GPA07_05630	COG3628	GPW Gp25 family protein
GPA07_05635	COG3299	homolog of phage Mu protein gp47
GPA07_05640	COG3778	Protein conserved in bacteria
GPA07_05695	COG3409	Peptidoglycan-binding domain 1 protein
GPA07_05695	COG5632	N-Acetylmuramoyl-L-alanine amidase
GPA07_05715	COG1510	regulation of RNA biosynthetic process
GPA07_05730	COG2318	DinB family
GPA07_05735	COG1585	Membrane protein implicated in regulation of membrane protease activity
GPA07_05740	COG2268	Band 7 protein
GPA07_05745	COG0772	Belongs to the SEDS family
GPA07_05750	COG0772	Belongs to the SEDS family
GPA07_05755	COG3339	Conserved Protein
GPA07_05760	COG1247	-acetyltransferase
GPA07_05770	COG3859	Proton-coupled thiamine transporter YuaJ
GPA07_05900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPA07_05905	COG1575	Belongs to the MenA family. Type 1 subfamily
GPA07_05910	COG1169	isochorismate synthase
GPA07_05915	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPA07_05920	COG0596	Alpha beta hydrolase
GPA07_05925	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPA07_05930	COG0318	PFAM AMP-dependent synthetase and ligase
GPA07_05935	COG4948	Mandelate Racemase Muconate Lactonizing
GPA07_05950	COG1294	oxidase, subunit
GPA07_05955	COG1271	oxidase subunit
GPA07_05960	COG0254	rRNA binding
GPA07_05965	COG0803	Belongs to the bacterial solute-binding protein 9 family
GPA07_05965	COG3443	Belongs to the bacterial solute-binding protein 9 family
GPA07_05970	COG0288	reversible hydration of carbon dioxide
GPA07_05975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPA07_05980	COG1854	S-ribosylhomocysteine lyase activity
GPA07_05995	COG0783	Belongs to the Dps family
GPA07_06005	COG4824	toxin secretion phage lysis holin
GPA07_06025	COG2310	stress, protein
GPA07_06030	COG0494	nUDIX hydrolase
GPA07_06035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPA07_06040	COG1116	anion transmembrane transporter activity
GPA07_06045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPA07_06065	COG1233	COG1233 Phytoene dehydrogenase and related
GPA07_06070	COG1506	peptidase
GPA07_06080	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPA07_06085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPA07_06090	COG0367	asparagine synthase
GPA07_06095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPA07_06100	COG2267	carboxylic ester hydrolase activity
GPA07_06110	COG4326	sporulation control protein
GPA07_06115	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GPA07_06120	COG1242	4 iron, 4 sulfur cluster binding
GPA07_06135	COG1725	Transcriptional regulator
GPA07_06140	COG1131	(ABC) transporter
GPA07_06150	COG1136	(ABC) transporter
GPA07_06155	COG0577	efflux transmembrane transporter activity
GPA07_06160	COG2433	Pfam Transposase IS66
GPA07_06165	COG1366	Belongs to the anti-sigma-factor antagonist family
GPA07_06165	COG2202	Pas domain
GPA07_06175	COG0495	leucyl-tRNA aminoacylation
GPA07_06180	COG1073	alpha beta
GPA07_06185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPA07_06190	COG0395	ABC-type sugar transport system, permease component
GPA07_06195	COG1653	transport
GPA07_06200	COG1733	regulation of RNA biosynthetic process
GPA07_06205	COG2207	Transcriptional regulator
GPA07_06210	COG4209	transmembrane transport
GPA07_06215	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GPA07_06220	COG1653	transport
GPA07_06225	COG0673	inositol 2-dehydrogenase activity
GPA07_06230	COG5578	integral membrane protein
GPA07_06235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPA07_06265	COG2081	HI0933 family
GPA07_06270	COG2244	polysaccharide biosynthetic process
GPA07_06275	COG1187	pseudouridine synthase activity
GPA07_06280	COG1349	DNA-binding transcription factor activity
GPA07_06285	COG2252	PERMEase
GPA07_06290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPA07_06300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPA07_06305	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GPA07_06315	COG1597	lipid kinase activity
GPA07_06320	COG0510	thiamine kinase activity
GPA07_06330	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPA07_06335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPA07_06340	COG0281	malic enzyme
GPA07_06345	COG5584	Small secreted protein
GPA07_06350	COG1363	Peptidase, m42
GPA07_06365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPA07_06370	COG4848	Belongs to the UPF0354 family
GPA07_06375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPA07_06380	COG1674	ftsk spoiiie
GPA07_06385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPA07_06390	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GPA07_06395	COG4980	gas vesicle protein
GPA07_06400	COG3118	belongs to the thioredoxin family
GPA07_06405	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GPA07_06405	COG1605	Chorismate mutase
GPA07_06410	COG1609	Transcriptional regulator
GPA07_06415	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPA07_06420	COG0517	IMP dehydrogenase activity
GPA07_06425	COG0454	-acetyltransferase
GPA07_06430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPA07_06435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPA07_06445	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPA07_06470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GPA07_06480	COG1335	isochorismatase
GPA07_06490	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPA07_06495	COG1956	GAF domain-containing protein
GPA07_06500	COG1309	transcriptional regulator
GPA07_06505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPA07_06510	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GPA07_06515	COG1114	Component of the transport system for branched-chain amino acids
GPA07_06520	COG1114	Component of the transport system for branched-chain amino acids
GPA07_06525	COG1104	cysteine desulfurase activity
GPA07_06530	COG0301	tRNA thio-modification
GPA07_06540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPA07_06565	COG1279	arginine transmembrane transporter activity
GPA07_06590	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPA07_06595	COG0402	S-adenosylhomocysteine deaminase activity
GPA07_06605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPA07_06610	COG2197	response regulator
GPA07_06615	COG4585	Histidine kinase
GPA07_06620	COG3239	Fatty acid desaturase
GPA07_06635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPA07_06640	COG0616	signal peptide processing
GPA07_06645	COG1714	RDD family
GPA07_06655	COG3874	Sporulation protein YtfJ
GPA07_06660	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GPA07_06665	COG0827	DNA restriction-modification system
GPA07_06670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPA07_06675	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPA07_06680	COG0137	argininosuccinate synthase activity
GPA07_06685	COG0165	Argininosuccinate lyase
GPA07_06695	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_06700	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GPA07_06710	COG4109	DRTGG domain
GPA07_06720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GPA07_06740	COG0587	DNA-directed DNA polymerase activity
GPA07_06745	COG0281	malic enzyme
GPA07_06750	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPA07_06755	COG0825	malonyl-CoA metabolic process
GPA07_06760	COG0205	6-phosphofructokinase activity
GPA07_06770	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPA07_06775	COG0628	permease
GPA07_06780	COG2707	UPF0756 membrane protein
GPA07_06785	COG0372	Belongs to the citrate synthase family
GPA07_06790	COG0538	isocitrate dehydrogenase activity
GPA07_06795	COG0039	L-malate dehydrogenase activity
GPA07_06800	COG0745	RESPONSE REGULATOR receiver
GPA07_06805	COG5002	protein histidine kinase activity
GPA07_06810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPA07_06810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPA07_06815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPA07_06820	COG1971	Probably functions as a manganese efflux pump
GPA07_06825	COG0237	dephospho-CoA kinase activity
GPA07_06830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPA07_06835	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GPA07_06845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPA07_06850	COG3611	Membrane attachment protein
GPA07_06855	COG1484	DNA-dependent DNA replication
GPA07_06860	COG0398	Pfam SNARE associated Golgi protein
GPA07_06870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPA07_06885	COG3275	phosphorelay sensor kinase activity
GPA07_06890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPA07_06895	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GPA07_06900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPA07_06905	COG3326	Membrane
GPA07_06915	COG1363	Peptidase, m42
GPA07_06920	COG1966	Carbon starvation protein
GPA07_06930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPA07_06935	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPA07_06940	COG0072	phenylalanine-tRNA ligase activity
GPA07_06940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPA07_06945	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPA07_06950	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPA07_06955	COG1286	toxin biosynthetic process
GPA07_06960	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPA07_06960	COG1796	DNA polymerase
GPA07_06965	COG1193	negative regulation of DNA recombination
GPA07_06970	COG3766	membrane
GPA07_06980	COG0318	PFAM AMP-dependent synthetase and ligase
GPA07_06985	COG1309	transcriptional regulator
GPA07_06990	COG1024	Enoyl-CoA hydratase
GPA07_06995	COG2086	electron transfer activity
GPA07_07000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GPA07_07005	COG3118	belongs to the thioredoxin family
GPA07_07010	COG0322	excinuclease ABC activity
GPA07_07015	COG0527	aspartate kinase activity
GPA07_07030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPA07_07040	COG1719	4-vinyl reductase, 4VR
GPA07_07045	COG2009	succinate dehydrogenase
GPA07_07050	COG1053	succinate dehydrogenase
GPA07_07055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPA07_07060	COG0824	Thioesterase
GPA07_07070	COG2197	response regulator
GPA07_07075	COG1846	Transcriptional regulator
GPA07_07080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPA07_07085	COG5401	PFAM Sporulation and spore germination
GPA07_07090	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPA07_07095	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPA07_07100	COG0622	Phosphoesterase
GPA07_07130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPA07_07135	COG1696	Membrane protein involved in D-alanine export
GPA07_07140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPA07_07145	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GPA07_07150	COG3339	Conserved Protein
GPA07_07160	COG2706	6-phosphogluconolactonase activity
GPA07_07165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPA07_07170	COG0028	Belongs to the TPP enzyme family
GPA07_07175	COG0440	acetolactate synthase activity
GPA07_07180	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPA07_07185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPA07_07190	COG0473	3-isopropylmalate dehydrogenase activity
GPA07_07195	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPA07_07200	COG0066	3-isopropylmalate dehydratase activity
GPA07_07205	COG1477	protein flavinylation
GPA07_07205	COG0457	Tetratricopeptide repeat
GPA07_07210	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPA07_07215	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPA07_07220	COG0470	DNA polymerase III
GPA07_07220	COG1067	ATP-dependent peptidase activity
GPA07_07225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPA07_07230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GPA07_07245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPA07_07250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPA07_07255	COG0181	hydroxymethylbilane synthase activity
GPA07_07260	COG1587	Uroporphyrinogen-III synthase
GPA07_07265	COG0113	porphobilinogen synthase activity
GPA07_07270	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPA07_07275	COG1388	LysM domain
GPA07_07280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPA07_07290	COG0525	valine-tRNA ligase activity
GPA07_07295	COG0285	dihydrofolate synthase activity
GPA07_07300	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GPA07_07310	COG0424	maF-like protein
GPA07_07315	COG2003	Belongs to the UPF0758 family
GPA07_07320	COG1077	Cell shape determining protein MreB Mrl
GPA07_07325	COG1792	Involved in formation and maintenance of cell shape
GPA07_07330	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPA07_07335	COG0850	regulation of cytokinetic process
GPA07_07340	COG2894	cell division
GPA07_07345	COG0739	heme binding
GPA07_07350	COG1994	Peptidase M50
GPA07_07355	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPA07_07360	COG2868	ribosomal protein
GPA07_07365	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GPA07_07370	COG3290	protein histidine kinase activity
GPA07_07375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPA07_07380	COG4492	Belongs to the UPF0735 family
GPA07_07385	COG0077	Prephenate dehydratase
GPA07_07390	COG1827	regulation of RNA biosynthetic process
GPA07_07395	COG1104	cysteine desulfurase activity
GPA07_07400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPA07_07405	COG0157	Belongs to the NadC ModD family
GPA07_07410	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPA07_07415	COG1388	LysM domain
GPA07_07435	COG2112	serine threonine protein kinase
GPA07_07445	COG0632	four-way junction helicase activity
GPA07_07450	COG2255	four-way junction helicase activity
GPA07_07460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPA07_07465	COG0343	queuine tRNA-ribosyltransferase activity
GPA07_07470	COG1862	Preprotein translocase
GPA07_07480	COG2323	membrane
GPA07_07485	COG2244	polysaccharide biosynthetic process
GPA07_07495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPA07_07495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPA07_07500	COG0490	domain, Protein
GPA07_07505	COG5416	Lipopolysaccharide assembly protein A domain
GPA07_07510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPA07_07510	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GPA07_07515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPA07_07520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPA07_07525	COG1490	D-aminoacyl-tRNA deacylase activity
GPA07_07530	COG4991	sh3 domain protein
GPA07_07530	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPA07_07530	COG3103	Sh3 type 3 domain protein
GPA07_07535	COG0124	histidyl-tRNA synthetase
GPA07_07550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPA07_07555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPA07_07560	COG1959	2 iron, 2 sulfur cluster binding
GPA07_07565	COG1104	cysteine desulfurase activity
GPA07_07570	COG0482	sulfurtransferase activity
GPA07_07575	COG0457	Tetratricopeptide repeat
GPA07_07580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPA07_07585	COG3881	PFAM PRC-barrel domain
GPA07_07600	COG0765	amino acid transport
GPA07_07605	COG0765	amino acid transport
GPA07_07610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA07_07615	COG1126	abc transporter atp-binding protein
GPA07_07620	COG0628	permease
GPA07_07625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPA07_07630	COG4472	Bacterial protein of unknown function (DUF965)
GPA07_07635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPA07_07640	COG3906	Belongs to the UPF0473 family
GPA07_07650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPA07_07670	COG0572	uridine kinase
GPA07_07675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPA07_07680	COG0768	penicillin binding
GPA07_07695	COG2226	methyltransferase
GPA07_07700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPA07_07705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPA07_07710	COG0626	cystathionine gamma-synthase activity
GPA07_07735	COG2226	methyltransferase
GPA07_07740	COG1063	alcohol dehydrogenase
GPA07_07745	COG1131	(ABC) transporter
GPA07_07750	COG0842	Transport permease protein
GPA07_07750	COG1511	domain protein
GPA07_07755	COG0842	Transport permease protein
GPA07_07760	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_07770	COG1063	alcohol dehydrogenase
GPA07_07780	COG0765	amino acid transport
GPA07_07785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA07_07790	COG1126	abc transporter atp-binding protein
GPA07_07795	COG1960	acyl-CoA dehydrogenase activity
GPA07_07875	COG1733	regulation of RNA biosynthetic process
GPA07_07880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GPA07_07885	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPA07_07925	COG0726	polysaccharide deacetylase
GPA07_07975	COG0457	Tetratricopeptide repeat
GPA07_07985	COG2755	lipolytic protein G-D-S-L family
GPA07_07995	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GPA07_08000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPA07_08005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPA07_08010	COG1534	Rna-binding protein
GPA07_08015	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPA07_08020	COG1713	HD superfamily hydrolase involved in NAD metabolism
GPA07_08025	COG0799	negative regulation of ribosome biogenesis
GPA07_08030	COG2226	methyltransferase
GPA07_08035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPA07_08040	COG1555	photosystem II stabilization
GPA07_08040	COG1596	polysaccharide export
GPA07_08045	COG2131	deaminase
GPA07_08050	COG0658	competence protein
GPA07_08050	COG2333	competence protein COMEC
GPA07_08060	COG1466	dna polymerase III delta subunit
GPA07_08065	COG0268	Binds directly to 16S ribosomal RNA
GPA07_08070	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GPA07_08075	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPA07_08085	COG0481	GTPase activity
GPA07_08090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPA07_08095	COG1420	regulation of RNA biosynthetic process
GPA07_08100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPA07_08105	COG0443	Heat shock 70 kDa protein
GPA07_08110	COG0484	heat shock protein binding
GPA07_08115	COG2264	protein methyltransferase activity
GPA07_08120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPA07_08125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPA07_08130	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPA07_08135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPA07_08140	COG1610	YqeY-like protein
GPA07_08145	COG1030	water channel activity
GPA07_08150	COG4864	UPF0365 protein
GPA07_08165	COG0561	phosphatase activity
GPA07_08170	COG1702	phosphate starvation-inducible protein PhoH
GPA07_08175	COG1480	7TM receptor with intracellular HD hydrolase
GPA07_08180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPA07_08185	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPA07_08190	COG0295	cytidine deaminase activity
GPA07_08195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPA07_08205	COG1381	Involved in DNA repair and RecF pathway recombination
GPA07_08210	COG0752	glycyl-tRNA synthetase alpha subunit
GPA07_08215	COG0751	glycine-tRNA ligase activity
GPA07_08220	COG0517	IMP dehydrogenase activity
GPA07_08225	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GPA07_08230	COG1671	Belongs to the UPF0178 family
GPA07_08235	COG0358	DNA primase activity
GPA07_08240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPA07_08245	COG2010	Cytochrome c
GPA07_08250	COG2384	SAM-dependent methyltransferase
GPA07_08255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPA07_08260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPA07_08270	COG0513	Belongs to the DEAD box helicase family
GPA07_08285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPA07_08290	COG1121	(ABC) transporter
GPA07_08295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPA07_08300	COG0735	belongs to the Fur family
GPA07_08305	COG1940	carbohydrate kinase activity
GPA07_08310	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GPA07_08315	COG4709	membrane
GPA07_08320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPA07_08325	COG1388	LysM domain
GPA07_08330	COG5521	maltodextrose utilization protein MalA
GPA07_08335	COG2839	Protein conserved in bacteria
GPA07_08340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GPA07_08345	COG0477	Major facilitator Superfamily
GPA07_08355	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPA07_08360	COG0573	inorganic phosphate transmembrane transporter activity
GPA07_08365	COG0581	inorganic phosphate transmembrane transporter activity
GPA07_08370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPA07_08375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPA07_08380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPA07_08390	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPA07_08395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPA07_08405	COG0705	Rhomboid family
GPA07_08405	COG0457	Tetratricopeptide repeat
GPA07_08410	COG4483	Protein conserved in bacteria
GPA07_08415	COG1940	carbohydrate kinase activity
GPA07_08420	COG1368	sulfuric ester hydrolase activity
GPA07_08425	COG2866	Carboxypeptidase
GPA07_08430	COG2814	Major facilitator Superfamily
GPA07_08435	COG0011	TIGRFAM Protein of
GPA07_08445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPA07_08455	COG1393	Belongs to the ArsC family
GPA07_08465	COG1366	Belongs to the anti-sigma-factor antagonist family
GPA07_08470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPA07_08475	COG1459	type II secretion system
GPA07_08480	COG4537	Required for transformation and DNA binding
GPA07_08485	COG4970	Tfp pilus assembly protein FimT
GPA07_08520	COG0681	Belongs to the peptidase S26 family
GPA07_08545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPA07_08550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GPA07_08555	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPA07_08560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPA07_08565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPA07_08570	COG0095	Lipoate-protein ligase
GPA07_08575	COG1321	iron dependent repressor
GPA07_08580	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPA07_08590	COG3872	metal-dependent enzyme
GPA07_08600	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GPA07_08605	COG0006	proline dipeptidase activity
GPA07_08610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPA07_08620	COG3854	ATPases associated with a variety of cellular activities
GPA07_08660	COG0511	ligase activity, forming carbon-carbon bonds
GPA07_08665	COG0439	Biotin carboxylase
GPA07_08670	COG1302	Protein conserved in bacteria
GPA07_08675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPA07_08680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPA07_08685	COG1570	exodeoxyribonuclease VII activity
GPA07_08690	COG1722	exodeoxyribonuclease VII activity
GPA07_08695	COG0142	geranyltranstransferase activity
GPA07_08700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPA07_08705	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GPA07_08710	COG1438	arginine binding
GPA07_08715	COG0497	DNA recombination
GPA07_08720	COG0750	zinc metalloprotease
GPA07_08725	COG0745	RESPONSE REGULATOR receiver
GPA07_08730	COG0457	Tetratricopeptide repeat
GPA07_08735	COG0584	glycerophosphoryl diester phosphodiesterase
GPA07_08745	COG3829	transcription factor binding
GPA07_08745	COG3290	protein histidine kinase activity
GPA07_08750	COG0280	phosphate acetyltransferase
GPA07_08755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GPA07_08760	COG3426	butyrate kinase activity
GPA07_08765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPA07_08770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GPA07_08775	COG0022	dehydrogenase e1 component
GPA07_08780	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPA07_08790	COG1597	lipid kinase activity
GPA07_08800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA07_08805	COG0765	amino acid transport
GPA07_08810	COG1126	abc transporter atp-binding protein
GPA07_08815	COG4129	membrane
GPA07_08820	COG1376	ErfK ybiS ycfS ynhG family protein
GPA07_08830	COG0346	lactoylglutathione lyase activity
GPA07_08835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPA07_08840	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPA07_08845	COG0835	chemotaxis
GPA07_08850	COG0706	membrane insertase activity
GPA07_08860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPA07_08865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPA07_08875	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_08880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA07_08885	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPA07_08890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA07_08895	COG2723	6-phospho-beta-galactosidase activity
GPA07_08900	COG2188	Transcriptional regulator
GPA07_08905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPA07_08910	COG1234	tRNA 3'-trailer cleavage
GPA07_08915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPA07_08920	COG0596	Alpha beta hydrolase
GPA07_08925	COG1902	pentaerythritol trinitrate reductase activity
GPA07_08930	COG4187	Peptidase family M20/M25/M40
GPA07_08935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPA07_08955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPA07_08960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPA07_08965	COG0300	oxidoreductase activity
GPA07_08970	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPA07_08975	COG1072	(Pantothenic acid kinase))
GPA07_08980	COG2211	Major facilitator Superfamily
GPA07_08990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPA07_08995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPA07_09010	COG0456	acetyltransferase
GPA07_09015	COG0456	acetyltransferase
GPA07_09015	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPA07_09020	COG4918	Iron-sulphur cluster biosynthesis
GPA07_09030	COG0457	Tetratricopeptide repeat
GPA07_09035	COG1073	alpha beta
GPA07_09045	COG0667	Aldo Keto reductase
GPA07_09050	COG0494	nUDIX hydrolase
GPA07_09055	COG1379	DNA repair
GPA07_09060	COG2153	protein acetylation
GPA07_09070	COG1404	Belongs to the peptidase S8 family
GPA07_09075	COG1300	Membrane
GPA07_09080	COG0735	belongs to the Fur family
GPA07_09090	COG4974	Belongs to the 'phage' integrase family
GPA07_09095	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPA07_09100	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GPA07_09105	COG1686	Belongs to the peptidase S11 family
GPA07_09110	COG1366	Belongs to the anti-sigma-factor antagonist family
GPA07_09115	COG2172	sigma factor antagonist activity
GPA07_09120	COG1191	sigma factor activity
GPA07_09155	COG0457	Tetratricopeptide repeat
GPA07_09180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPA07_09195	COG0697	spore germination
GPA07_09200	COG0019	diaminopimelate decarboxylase activity
GPA07_09205	COG4086	secreted protein
GPA07_09210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPA07_09225	COG0307	riboflavin synthase, alpha
GPA07_09230	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPA07_09230	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPA07_09235	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GPA07_09240	COG0456	acetyltransferase
GPA07_09245	COG1547	Domain of unknown function (DUF309)
GPA07_09255	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GPA07_09260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GPA07_09270	COG1686	Belongs to the peptidase S11 family
GPA07_09275	COG2715	membrane protein required for spore maturation
GPA07_09280	COG0700	Nucleoside recognition
GPA07_09285	COG1187	pseudouridine synthase activity
GPA07_09290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPA07_09295	COG1333	cytochrome c biogenesis protein
GPA07_09300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPA07_09305	COG0745	RESPONSE REGULATOR receiver
GPA07_09310	COG5002	protein histidine kinase activity
GPA07_09315	COG1595	DNA-templated transcription, initiation
GPA07_09330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPA07_09335	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GPA07_09340	COG1141	Ferredoxin
GPA07_09345	COG4955	Helix-turn-helix domain
GPA07_09350	COG0514	ATP-dependent DNA helicase (RecQ)
GPA07_09355	COG1266	CAAX protease self-immunity
GPA07_09360	COG1388	LysM domain
GPA07_09370	COG1408	metallophosphoesterase
GPA07_09375	COG4862	establishment of competence for transformation
GPA07_09380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GPA07_09385	COG0492	ferredoxin-NADP+ reductase activity
GPA07_09390	COG2339	peptidase activity
GPA07_09395	COG3773	Cell wall hydrolase
GPA07_09395	COG3409	Peptidoglycan-binding domain 1 protein
GPA07_09400	COG2959	enzyme of heme biosynthesis
GPA07_09405	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GPA07_09415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPA07_09420	COG0539	negative regulation of cytoplasmic translation
GPA07_09425	COG1304	FMN binding
GPA07_09450	COG1160	GTP binding
GPA07_09455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GPA07_09470	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GPA07_09475	COG0776	regulation of translation
GPA07_09480	COG0302	gtp cyclohydrolase
GPA07_09490	COG0142	geranyltranstransferase activity
GPA07_09495	COG2226	methyltransferase
GPA07_09500	COG0142	geranyltranstransferase activity
GPA07_09505	COG0105	UTP biosynthetic process
GPA07_09510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPA07_09515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPA07_09520	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPA07_09525	COG4401	Chorismate mutase type I
GPA07_09540	COG0134	indole-3-glycerol-phosphate synthase activity
GPA07_09545	COG0135	phosphoribosylanthranilate isomerase activity
GPA07_09550	COG0133	tryptophan synthase activity
GPA07_09555	COG0159	tryptophan synthase activity
GPA07_09560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPA07_09565	COG0287	Prephenate dehydrogenase
GPA07_09570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPA07_09575	COG0457	Tetratricopeptide repeat
GPA07_09580	COG5582	Belongs to the UPF0302 family
GPA07_09590	COG0723	plastoquinol--plastocyanin reductase activity
GPA07_09595	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPA07_09600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPA07_09600	COG2010	Cytochrome c
GPA07_09605	COG4347	Protein of unknown function (DUF1405)
GPA07_09615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPA07_09620	COG1694	Mazg nucleotide pyrophosphohydrolase
GPA07_09625	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GPA07_09630	COG1803	Methylglyoxal synthase
GPA07_09635	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GPA07_09640	COG0438	transferase activity, transferring glycosyl groups
GPA07_09645	COG0617	tRNA 3'-terminal CCA addition
GPA07_09655	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPA07_09660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPA07_09665	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GPA07_09670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPA07_09670	COG1199	ATP-dependent helicase activity
GPA07_09680	COG5353	protein conserved in bacteria
GPA07_09685	COG0017	Asparaginyl-tRNA synthetase
GPA07_09690	COG3935	DnaD domain protein
GPA07_09695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPA07_09705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPA07_09705	COG4499	WXG100 protein secretion system (Wss), protein YukC
GPA07_09710	COG3331	DNA recombination
GPA07_09740	COG0071	Belongs to the small heat shock protein (HSP20) family
GPA07_09745	COG2190	(PTS) system
GPA07_09760	COG1111	helicase
GPA07_09760	COG1205	dead DEAH box helicase
GPA07_09765	COG3359	exonuclease
GPA07_09775	COG4474	Belongs to the UPF0398 family
GPA07_09780	COG3599	regulation of cell shape
GPA07_09790	COG0116	Belongs to the methyltransferase superfamily
GPA07_09800	COG1199	ATP-dependent helicase activity
GPA07_09805	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPA07_09810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPA07_09815	COG2233	PERMEase
GPA07_09820	COG3424	synthase
GPA07_09825	COG1755	Isoprenylcysteine carboxyl methyltransferase
GPA07_09835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GPA07_09845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPA07_09855	COG0328	RNA-DNA hybrid ribonuclease activity
GPA07_09860	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPA07_09865	COG0328	RNA-DNA hybrid ribonuclease activity
GPA07_09880	COG1278	Cold shock
GPA07_09895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPA07_09900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPA07_09905	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPA07_09910	COG0386	Belongs to the glutathione peroxidase family
GPA07_09915	COG1418	mRNA catabolic process
GPA07_09920	COG1413	lyase activity
GPA07_09925	COG0129	dihydroxy-acid dehydratase activity
GPA07_09935	COG2136	Putative SAM-dependent methyltransferase
GPA07_09935	COG2521	methyltransferase
GPA07_09945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPA07_09955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPA07_09960	COG0204	Acyl-transferase
GPA07_09965	COG1272	protein, Hemolysin III
GPA07_09970	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPA07_09975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GPA07_09990	COG1999	signal sequence binding
GPA07_09995	COG2755	lipolytic protein G-D-S-L family
GPA07_10000	COG4698	Protein conserved in bacteria
GPA07_10020	COG1846	Transcriptional regulator
GPA07_10025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPA07_10030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPA07_10035	COG1086	Polysaccharide biosynthesis protein
GPA07_10045	COG4641	Protein conserved in bacteria
GPA07_10060	COG0463	Glycosyl transferase, family 2
GPA07_10065	COG3829	transcription factor binding
GPA07_10070	COG1509	lysine 2,3-aminomutase activity
GPA07_10080	COG4479	Belongs to the UPF0346 family
GPA07_10095	COG0671	phosphoesterase, PA-phosphatase related
GPA07_10105	COG0813	purine-nucleoside phosphorylase activity
GPA07_10110	COG1876	peptidase activity
GPA07_10120	COG2226	methyltransferase
GPA07_10125	COG0793	Belongs to the peptidase S41A family
GPA07_10125	COG3409	Peptidoglycan-binding domain 1 protein
GPA07_10130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPA07_10140	COG0778	Nitroreductase
GPA07_10145	COG1733	regulation of RNA biosynthetic process
GPA07_10160	COG2962	Rard protein
GPA07_10170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GPA07_10175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GPA07_10185	COG0534	Mate efflux family protein
GPA07_10190	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPA07_10195	COG0791	NLP P60 protein
GPA07_10195	COG1388	LysM domain
GPA07_10200	COG2032	superoxide dismutase activity
GPA07_10205	COG0714	Associated with various cellular activities
GPA07_10210	COG4548	von Willebrand factor, type A
GPA07_10215	COG0567	Dehydrogenase, E1 component
GPA07_10220	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPA07_10225	COG0385	Bile acid
GPA07_10230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GPA07_10235	COG1657	PFAM Prenyltransferase squalene oxidase
GPA07_10240	COG1012	belongs to the aldehyde dehydrogenase family
GPA07_10265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPA07_10275	COG0514	ATP-dependent DNA helicase (RecQ)
GPA07_10280	COG1388	LysM domain
GPA07_10280	COG3584	3D domain protein
GPA07_10290	COG2322	membrane
GPA07_10295	COG0372	Belongs to the citrate synthase family
GPA07_10300	COG2079	MmgE PrpD family protein
GPA07_10305	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPA07_10310	COG0741	lytic transglycosylase activity
GPA07_10315	COG0531	amino acid
GPA07_10320	COG0640	Transcriptional regulator
GPA07_10335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPA07_10340	COG1309	transcriptional regulator
GPA07_10360	COG1994	Peptidase M50
GPA07_10365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPA07_10370	COG0243	molybdopterin cofactor binding
GPA07_10380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPA07_10385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPA07_10390	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPA07_10400	COG1132	(ABC) transporter
GPA07_10410	COG0583	DNA-binding transcription factor activity
GPA07_10415	COG0069	glutamate synthase activity
GPA07_10415	COG0070	glutamate synthase
GPA07_10415	COG0067	glutamate synthase
GPA07_10420	COG0493	'glutamate synthase
GPA07_10425	COG2223	nitrite transmembrane transporter activity
GPA07_10430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPA07_10435	COG0243	molybdopterin cofactor binding
GPA07_10440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPA07_10445	COG2146	nitrite reductase [NAD(P)H] activity
GPA07_10450	COG2323	membrane
GPA07_10460	COG4677	pectinesterase activity
GPA07_10465	COG2027	D-alanyl-D-alanine carboxypeptidase
GPA07_10470	COG0534	Mate efflux family protein
GPA07_10475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPA07_10485	COG1587	Uroporphyrinogen-III synthase
GPA07_10490	COG0586	Pfam SNARE associated Golgi protein
GPA07_10495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GPA07_10500	COG2246	polysaccharide biosynthetic process
GPA07_10505	COG0166	Belongs to the GPI family
GPA07_10515	COG0247	lactate metabolic process
GPA07_10520	COG0277	FAD linked oxidase domain protein
GPA07_10525	COG3835	regulator
GPA07_10535	COG1349	DNA-binding transcription factor activity
GPA07_10545	COG1649	PFAM Uncharacterised BCR, COG1649
GPA07_10550	COG1960	acyl-CoA dehydrogenase activity
GPA07_10555	COG0318	PFAM AMP-dependent synthetase and ligase
GPA07_10560	COG0439	Biotin carboxylase
GPA07_10565	COG0511	ligase activity, forming carbon-carbon bonds
GPA07_10570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPA07_10575	COG1024	Enoyl-CoA hydratase
GPA07_10580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPA07_10590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPA07_10595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPA07_10600	COG1012	belongs to the aldehyde dehydrogenase family
GPA07_10620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPA07_10630	COG2814	Major facilitator Superfamily
GPA07_10635	COG1846	Transcriptional regulator
GPA07_10640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA07_10655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPA07_10680	COG1486	melibiose metabolic process
GPA07_10685	COG1012	belongs to the aldehyde dehydrogenase family
GPA07_10715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPA07_10720	COG0187	DNA topoisomerase II activity
GPA07_10725	COG1832	CoA-binding protein
GPA07_10730	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GPA07_10735	COG4841	protein insertion into membrane
GPA07_10745	COG0824	Thioesterase
GPA07_10765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPA07_10770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GPA07_10785	COG0071	Belongs to the small heat shock protein (HSP20) family
GPA07_10795	COG4846	Membrane protein involved in cytochrome C biogenesis
GPA07_10800	COG0785	Cytochrome C biogenesis protein
GPA07_10810	COG3763	UPF0154 protein
GPA07_10820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPA07_10825	COG4224	UPF0291 protein
GPA07_10830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GPA07_10835	COG1388	LysM domain
GPA07_10840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPA07_10855	COG1366	Belongs to the anti-sigma-factor antagonist family
GPA07_10860	COG3209	COG3209 Rhs family protein
GPA07_10865	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPA07_10870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPA07_10870	COG2124	cytochrome p450
GPA07_10875	COG1309	transcriptional regulator
GPA07_10880	COG2323	membrane
GPA07_10895	COG1556	Lactate utilization protein
GPA07_10900	COG1139	Iron-sulfur cluster binding protein
GPA07_10905	COG0247	lactate metabolic process
GPA07_10915	COG0702	epimerase
GPA07_10920	COG1959	2 iron, 2 sulfur cluster binding
GPA07_10930	COG4876	unkown
GPA07_10935	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GPA07_10940	COG3285	dna ligase
GPA07_10940	COG1793	dna ligase
GPA07_10945	COG3619	membrane
GPA07_10955	COG0457	Tetratricopeptide repeat
GPA07_10975	COG5646	InterPro IPR014922
GPA07_11005	COG5444	nuclease activity
GPA07_11010	COG0300	oxidoreductase activity
GPA07_11025	COG4653	Phage capsid family
GPA07_11045	COG5518	Phage portal protein
GPA07_11090	COG0174	glutamine synthetase
GPA07_11095	COG0789	Transcriptional regulator
GPA07_11100	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GPA07_11105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPA07_11110	COG0464	growth
GPA07_11120	COG4112	unkown
GPA07_11125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPA07_11130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPA07_11135	COG1780	Probably involved in ribonucleotide reductase function
GPA07_11150	COG1923	regulation of RNA biosynthetic process
GPA07_11155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPA07_11185	COG1764	response to oxidative stress
GPA07_11190	COG4195	phage-related replication protein
GPA07_11195	COG1404	Belongs to the peptidase S8 family
GPA07_11200	COG0457	Tetratricopeptide repeat
GPA07_11205	COG4195	phage-related replication protein
GPA07_11210	COG1329	Transcriptional regulator
GPA07_11250	COG4974	Belongs to the 'phage' integrase family
GPA07_11255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPA07_11260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPA07_11270	COG4550	Control of competence regulator ComK, YlbF/YmcA
GPA07_11275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPA07_11280	COG0156	8-amino-7-oxononanoate synthase activity
GPA07_11285	COG1063	alcohol dehydrogenase
GPA07_11290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPA07_11295	COG2359	stage V sporulation protein S
GPA07_11300	COG1692	metallophosphoesterase
GPA07_11305	COG1418	mRNA catabolic process
GPA07_11310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPA07_11315	COG1058	Belongs to the CinA family
GPA07_11315	COG1546	Belongs to the CinA family
GPA07_11320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPA07_11325	COG1426	Protein conserved in bacteria
GPA07_11340	COG0300	oxidoreductase activity
GPA07_11345	COG1033	growth of symbiont in host cell
GPA07_11345	COG2409	Drug exporters of the RND superfamily
GPA07_11355	COG0612	Peptidase, M16
GPA07_11360	COG0612	Peptidase, M16
GPA07_11365	COG1033	growth of symbiont in host cell
GPA07_11365	COG2409	Drug exporters of the RND superfamily
GPA07_11370	COG2814	Major facilitator Superfamily
GPA07_11375	COG2188	Transcriptional regulator
GPA07_11380	COG1674	ftsk spoiiie
GPA07_11380	COG4980	gas vesicle protein
GPA07_11390	COG0740	serine-type endopeptidase activity
GPA07_11395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPA07_11405	COG0527	aspartate kinase activity
GPA07_11410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPA07_11415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPA07_11420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPA07_11425	COG1873	PFAM PRC-barrel domain
GPA07_11435	COG0612	Peptidase, M16
GPA07_11440	COG0726	polysaccharide deacetylase
GPA07_11445	COG1185	polyribonucleotide nucleotidyltransferase activity
GPA07_11450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPA07_11455	COG0196	riboflavin kinase activity
GPA07_11460	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPA07_11465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPA07_11470	COG1550	Protein conserved in bacteria
GPA07_11475	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPA07_11480	COG1358	cellular component organization or biogenesis
GPA07_11485	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GPA07_11490	COG0195	Participates in both transcription termination and antitermination
GPA07_11495	COG0779	Required for maturation of 30S ribosomal subunits
GPA07_11520	COG2176	DNA-directed DNA polymerase activity
GPA07_11525	COG0442	prolyl-tRNA aminoacylation
GPA07_11530	COG0750	zinc metalloprotease
GPA07_11535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GPA07_11540	COG4589	Belongs to the CDS family
GPA07_11545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPA07_11550	COG0233	cytoplasmic translational termination
GPA07_11555	COG0528	UMP kinase activity
GPA07_11560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPA07_11575	COG1191	sigma factor activity
GPA07_11585	COG1776	CheC inhibitor of MCP methylation
GPA07_11590	COG0835	chemotaxis
GPA07_11595	COG2198	Histidine kinase
GPA07_11595	COG0643	Histidine kinase
GPA07_11600	COG2201	protein-glutamate methylesterase activity
GPA07_11605	COG0455	bacterial-type flagellum organization
GPA07_11610	COG1419	protein localization to endoplasmic reticulum
GPA07_11615	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPA07_11620	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPA07_11625	COG1684	flagellar biosynthetic protein fliR
GPA07_11630	COG1987	bacterial-type flagellum assembly
GPA07_11635	COG1338	Plays a role in the flagellum-specific transport system
GPA07_11640	COG3190	flagellar
GPA07_11645	COG2201	protein-glutamate methylesterase activity
GPA07_11650	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPA07_11650	COG1776	CheC inhibitor of MCP methylation
GPA07_11655	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPA07_11660	COG1580	Controls the rotational direction of flagella during chemotaxis
GPA07_11665	COG1582	Flagellar protein (FlbD)
GPA07_11670	COG4786	Flagellar basal body rod
GPA07_11675	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPA07_11680	COG3144	bacterial-type flagellum assembly
GPA07_11690	COG2882	bacterial-type flagellum organization
GPA07_11695	COG1157	protein secretion by the type III secretion system
GPA07_11700	COG1317	bacterial-type flagellum organization
GPA07_11710	COG1766	The M ring may be actively involved in energy transduction
GPA07_11715	COG1677	Flagellar hook-basal body complex protein FliE
GPA07_11720	COG1558	bacterial-type flagellum-dependent cell motility
GPA07_11725	COG1815	bacterial-type flagellum-dependent cell motility
GPA07_11730	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GPA07_11735	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPA07_11740	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPA07_11745	COG4974	Belongs to the 'phage' integrase family
GPA07_11750	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GPA07_11755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPA07_11760	COG0758	DNA mediated transformation
GPA07_11765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GPA07_11770	COG0045	succinate-CoA ligase (ADP-forming) activity
GPA07_11775	COG2257	FlhB HrpN YscU SpaS Family
GPA07_11785	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPA07_11790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPA07_11795	COG0335	large ribosomal subunit rRNA binding
GPA07_11800	COG0336	Belongs to the RNA methyltransferase TrmD family
GPA07_11805	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPA07_11815	COG1837	Belongs to the UPF0109 family
GPA07_11820	COG0228	four-way junction DNA binding
GPA07_11825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPA07_11830	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GPA07_11835	COG0552	protein localization to endoplasmic reticulum
GPA07_11840	COG1196	nuclear chromosome segregation
GPA07_11850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPA07_11855	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_11860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GPA07_11865	COG0416	fatty acid biosynthetic process
GPA07_11870	COG1349	DNA-binding transcription factor activity
GPA07_11875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPA07_11880	COG1760	l-serine dehydratase
GPA07_11885	COG1760	l-serine dehydratase
GPA07_11890	COG1461	Dihydroxyacetone kinase
GPA07_11895	COG1302	Protein conserved in bacteria
GPA07_11900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GPA07_11910	COG1564	THIamine pyrophosphokinase
GPA07_11915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPA07_11920	COG1162	GTPase activity
GPA07_11925	COG0515	serine threonine protein kinase
GPA07_11925	COG2815	serine threonine protein kinase
GPA07_11930	COG0631	protein serine/threonine phosphatase activity
GPA07_11935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GPA07_11940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPA07_11940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPA07_11945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPA07_11950	COG0242	peptide deformylase activity
GPA07_11955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPA07_11960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPA07_11965	COG1758	RNA polymerase activity
GPA07_11970	COG0194	GDP metabolic process
GPA07_11975	COG2052	Domain of unknown function (DUF370)
GPA07_11980	COG1561	YicC-like family, N-terminal region
GPA07_11985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GPA07_11995	COG1648	precorrin-2 dehydrogenase activity
GPA07_12000	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GPA07_12005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPA07_12010	COG0529	Catalyzes the synthesis of activated sulfate
GPA07_12015	COG2046	Belongs to the sulfate adenylyltransferase family
GPA07_12020	COG0306	phosphate transporter
GPA07_12025	COG0175	sulfate reduction
GPA07_12035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPA07_12040	COG0284	orotidine-5'-phosphate decarboxylase activity
GPA07_12045	COG0167	dihydroorotate dehydrogenase activity
GPA07_12050	COG0543	2 iron, 2 sulfur cluster binding
GPA07_12055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPA07_12060	COG0505	Belongs to the CarA family
GPA07_12065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GPA07_12070	COG0540	Belongs to the ATCase OTCase family
GPA07_12075	COG2233	PERMEase
GPA07_12080	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GPA07_12085	COG0564	pseudouridine synthase activity
GPA07_12090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPA07_12095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPA07_12100	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPA07_12105	COG3599	regulation of cell shape
GPA07_12110	COG2302	S4 RNA-binding domain
GPA07_12115	COG0762	integral membrane protein
GPA07_12120	COG1799	cell septum assembly
GPA07_12125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPA07_12135	COG1873	PFAM PRC-barrel domain
GPA07_12140	COG1119	ATPase activity
GPA07_12150	COG3732	PTS system glucitol sorbitol-specific
GPA07_12155	COG3730	PTS system glucitol sorbitol-specific
GPA07_12170	COG2390	Transcriptional regulator
GPA07_12175	COG1191	sigma factor activity
GPA07_12180	COG1191	sigma factor activity
GPA07_12190	COG4412	M6 family metalloprotease domain protein
GPA07_12190	COG1404	Belongs to the peptidase S8 family
GPA07_12195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPA07_12200	COG0849	cell division
GPA07_12205	COG3856	small basic protein
GPA07_12210	COG3879	Bacterial protein of unknown function (DUF881)
GPA07_12215	COG3879	Bacterial protein of unknown function (DUF881)
GPA07_12220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPA07_12225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPA07_12230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPA07_12235	COG0772	Belongs to the SEDS family
GPA07_12240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPA07_12245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPA07_12250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPA07_12255	COG0768	penicillin binding
GPA07_12265	COG4839	cell division protein FtsL
GPA07_12270	COG0275	rRNA processing
GPA07_12275	COG2001	Belongs to the MraZ family
GPA07_12280	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GPA07_12285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPA07_12290	COG0454	-acetyltransferase
GPA07_12300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GPA07_12305	COG1399	metal-binding, possibly nucleic acid-binding protein
GPA07_12315	COG3480	Lon protease (S16) C-terminal proteolytic domain
GPA07_12320	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPA07_12325	COG3314	Sporulation integral membrane protein YlbJ
GPA07_12330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPA07_12335	COG0742	ribosomal rna small subunit methyltransferase
GPA07_12340	COG4471	UPF0298 protein
GPA07_12345	COG3679	Belongs to the UPF0342 family
GPA07_12365	COG2340	Cysteine-rich secretory protein family
GPA07_12370	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GPA07_12380	COG3336	cytochrome c oxidase
GPA07_12385	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GPA07_12390	COG1845	cytochrome c oxidase, subunit III
GPA07_12395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPA07_12400	COG2010	Cytochrome c
GPA07_12400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPA07_12405	COG0109	protoheme IX farnesyltransferase activity
GPA07_12410	COG1612	heme a metabolic process
GPA07_12420	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GPA07_12425	COG0772	Belongs to the SEDS family
GPA07_12430	COG4838	Belongs to the UPF0358 family
GPA07_12435	COG2066	Belongs to the glutaminase family
GPA07_12440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GPA07_12445	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPA07_12455	COG4896	Protein conserved in bacteria
GPA07_12485	COG0483	inositol monophosphate 1-phosphatase activity
GPA07_12495	COG4493	Belongs to the UPF0637 family
GPA07_12500	COG4476	Belongs to the UPF0223 family
GPA07_12505	COG1982	Orn Lys Arg decarboxylase major
GPA07_12515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPA07_12520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPA07_12525	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPA07_12530	COG0022	dehydrogenase e1 component
GPA07_12535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GPA07_12550	COG0242	peptide deformylase activity
GPA07_12555	COG0561	phosphatase activity
GPA07_12565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPA07_12570	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GPA07_12575	COG0569	domain protein
GPA07_12580	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GPA07_12580	COG2105	PFAM AIG2 family protein
GPA07_12585	COG3852	Histidine kinase
GPA07_12590	COG2002	toxin-antitoxin pair type II binding
GPA07_12595	COG1077	Cell shape determining protein MreB Mrl
GPA07_12600	COG2309	aminopeptidase activity
GPA07_12605	COG0488	(ABC) transporter
GPA07_12620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPA07_12620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA07_12620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPA07_12625	COG1105	Belongs to the carbohydrate kinase PfkB family
GPA07_12630	COG1349	DNA-binding transcription factor activity
GPA07_12635	COG0577	efflux transmembrane transporter activity
GPA07_12640	COG1136	(ABC) transporter
GPA07_12645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPA07_12660	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPA07_12665	COG0314	molybdopterin synthase activity
GPA07_12670	COG1763	Mo-molybdopterin cofactor biosynthetic process
GPA07_12675	COG0303	'Molybdopterin
GPA07_12680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPA07_12685	COG0746	molybdenum cofactor guanylyltransferase activity
GPA07_12700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPA07_12705	COG0450	alkyl hydroperoxide reductase
GPA07_12710	COG0668	transmembrane transport
GPA07_12720	COG1473	amidohydrolase
GPA07_12725	COG2171	N-acyltransferase activity
GPA07_12730	COG0716	FMN binding
GPA07_12740	COG0716	FMN binding
GPA07_12750	COG0583	DNA-binding transcription factor activity
GPA07_12755	COG0517	IMP dehydrogenase activity
GPA07_12765	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GPA07_12770	COG4703	Protein of unknown function (DUF1797)
GPA07_12775	COG3546	catalase activity
GPA07_12780	COG2200	EAL domain
GPA07_12785	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_12790	COG1408	metallophosphoesterase
GPA07_12795	COG1376	ErfK ybiS ycfS ynhG family protein
GPA07_12800	COG2814	Major facilitator Superfamily
GPA07_12815	COG0457	Tetratricopeptide repeat
GPA07_12835	COG0305	Participates in initiation and elongation during chromosome replication
GPA07_12850	COG0835	chemotaxis
GPA07_12850	COG0784	Response regulator, receiver
GPA07_12860	COG1714	RDD family
GPA07_12865	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPA07_12870	COG0436	Aminotransferase
GPA07_12875	COG4191	Histidine kinase
GPA07_12880	COG0768	penicillin binding
GPA07_12885	COG2340	Cysteine-rich secretory protein family
GPA07_12890	COG2084	Dehydrogenase
GPA07_12900	COG0840	transmembrane signaling receptor activity
GPA07_12905	COG1533	DNA photolyase activity
GPA07_12915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPA07_12920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA07_12925	COG2190	(PTS) system
GPA07_12925	COG1263	PTS System
GPA07_12925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA07_12930	COG3711	transcriptional antiterminator
GPA07_12935	COG1609	Transcriptional regulator
GPA07_12940	COG0006	proline dipeptidase activity
GPA07_12945	COG2217	Heavy metal translocating P-type atpase
GPA07_12950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPA07_12955	COG2244	polysaccharide biosynthetic process
GPA07_12960	COG3773	Cell wall hydrolase
GPA07_12970	COG4873	Protein conserved in bacteria
GPA07_12980	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPA07_12985	COG0602	queuosine metabolic process
GPA07_12990	COG0720	synthase
GPA07_12995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPA07_13000	COG3949	Membrane
GPA07_13005	COG0542	response to heat
GPA07_13015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPA07_13020	COG1360	Flagellar Motor Protein
GPA07_13025	COG1846	Transcriptional regulator
GPA07_13030	COG3852	Histidine kinase
GPA07_13040	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GPA07_13045	COG0235	Class ii aldolase
GPA07_13050	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GPA07_13055	COG1850	ribulose-bisphosphate carboxylase activity
GPA07_13060	COG0436	Aminotransferase
GPA07_13065	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GPA07_13070	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GPA07_13075	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPA07_13080	COG5002	protein histidine kinase activity
GPA07_13085	COG3594	Acyltransferase
GPA07_13095	COG2323	membrane
GPA07_13100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPA07_13105	COG0501	Belongs to the peptidase M48B family
GPA07_13125	COG1191	sigma factor activity
GPA07_13130	COG0861	Integral membrane protein TerC family
GPA07_13135	COG0586	Pfam SNARE associated Golgi protein
GPA07_13140	COG3300	MHYT domain
GPA07_13140	COG5001	Diguanylate cyclase
GPA07_13145	COG1846	Transcriptional regulator
GPA07_13160	COG0789	Transcriptional regulator
GPA07_13170	COG2239	Acts as a magnesium transporter
GPA07_13180	COG3212	peptidase
GPA07_13185	COG3212	peptidase
GPA07_13190	COG5002	protein histidine kinase activity
GPA07_13190	COG3850	Histidine kinase
GPA07_13195	COG0745	RESPONSE REGULATOR receiver
GPA07_13200	COG1404	Belongs to the peptidase S8 family
GPA07_13205	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPA07_13210	COG0590	tRNA wobble adenosine to inosine editing
GPA07_13215	COG1764	response to oxidative stress
GPA07_13220	COG1846	Transcriptional regulator
GPA07_13225	COG1764	response to oxidative stress
GPA07_13235	COG0457	Tetratricopeptide repeat
GPA07_13240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPA07_13245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPA07_13250	COG0788	formyltetrahydrofolate deformylase activity
GPA07_13260	COG2076	Multidrug Resistance protein
GPA07_13265	COG2076	Multidrug Resistance protein
GPA07_13275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPA07_13290	COG1695	Transcriptional regulator
GPA07_13295	COG1607	acyl-coa hydrolase
GPA07_13300	COG1834	amidinotransferase
GPA07_13305	COG4608	Belongs to the ABC transporter superfamily
GPA07_13310	COG0791	NLP P60 protein
GPA07_13315	COG4948	Mandelate Racemase Muconate Lactonizing
GPA07_13320	COG1619	proteins homologs of microcin C7 resistance protein MccF
GPA07_13325	COG4166	transmembrane transport
GPA07_13330	COG0444	Belongs to the ABC transporter superfamily
GPA07_13335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPA07_13340	COG0601	transmembrane transport
GPA07_13345	COG2362	D-Aminopeptidase
GPA07_13350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPA07_13355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPA07_13360	COG0346	lactoylglutathione lyase activity
GPA07_13365	COG0531	amino acid
GPA07_13375	COG2390	Transcriptional regulator
GPA07_13380	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_13385	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_13390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPA07_13400	COG0022	dehydrogenase e1 component
GPA07_13400	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPA07_13405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GPA07_13410	COG1063	alcohol dehydrogenase
GPA07_13425	COG3775	system Galactitol-specific IIC component
GPA07_13435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GPA07_13440	COG4208	sulfate ABC transporter
GPA07_13450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GPA07_13455	COG0405	Gamma-glutamyltransferase
GPA07_13465	COG1392	Phosphate transport regulator
GPA07_13470	COG0306	phosphate transporter
GPA07_13485	COG3409	Peptidoglycan-binding domain 1 protein
GPA07_13485	COG5632	N-Acetylmuramoyl-L-alanine amidase
GPA07_13490	COG2856	Zn peptidase
GPA07_13495	COG4195	phage-related replication protein
GPA07_13515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPA07_13520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPA07_13535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPA07_13555	COG0457	Tetratricopeptide repeat
GPA07_13610	COG3409	Peptidoglycan-binding domain 1 protein
GPA07_13610	COG5632	N-Acetylmuramoyl-L-alanine amidase
GPA07_13645	COG3778	Protein conserved in bacteria
GPA07_13650	COG3299	homolog of phage Mu protein gp47
GPA07_13655	COG3628	GPW Gp25 family protein
GPA07_13665	COG4193	domain, Protein
GPA07_13670	COG1652	LysM domain
GPA07_13675	COG3953	SLT domain
GPA07_13675	COG5280	Phage tail tape measure protein TP901
GPA07_13675	COG3953	SLT domain
GPA07_13675	COG5280	Phage tail tape measure protein TP901
GPA07_13730	COG4653	Phage capsid family
GPA07_13735	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPA07_13755	COG1783	phage Terminase large subunit
GPA07_13760	COG5484	DNA packaging
GPA07_13775	COG3677	Transposase
GPA07_13790	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPA07_13810	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GPA07_13875	COG1476	TRANSCRIPTIONal
GPA07_13880	COG3620	sequence-specific DNA binding
GPA07_13895	COG0582	viral genome integration into host DNA
GPA07_13905	COG0626	cystathionine gamma-synthase activity
GPA07_13910	COG0626	cystathionine gamma-synthase activity
GPA07_13915	COG2382	esterase
GPA07_13920	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GPA07_13925	COG2153	protein acetylation
GPA07_13935	COG0210	DNA helicase
GPA07_13990	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPA07_13995	COG0351	phosphomethylpyrimidine kinase
GPA07_14000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPA07_14005	COG2022	thiamine diphosphate biosynthetic process
GPA07_14010	COG2104	thiamine diphosphate biosynthetic process
GPA07_14020	COG0352	thiamine-phosphate diphosphorylase activity
GPA07_14025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPA07_14030	COG0475	glutathione-regulated potassium exporter activity
GPA07_14030	COG0569	domain protein
GPA07_14035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GPA07_14040	COG0564	pseudouridine synthase activity
GPA07_14045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPA07_14050	COG2357	RelA SpoT domain protein
GPA07_14060	COG4116	CYTH
GPA07_14065	COG0741	lytic transglycosylase activity
GPA07_14070	COG2346	COG2346, Truncated hemoglobins
GPA07_14080	COG1164	Oligoendopeptidase f
GPA07_14090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPA07_14095	COG4862	establishment of competence for transformation
GPA07_14100	COG0861	Integral membrane protein TerC family
GPA07_14105	COG1393	Belongs to the ArsC family
GPA07_14110	COG0456	acetyltransferase
GPA07_14115	COG4608	Belongs to the ABC transporter superfamily
GPA07_14120	COG0444	Belongs to the ABC transporter superfamily
GPA07_14125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPA07_14130	COG0601	transmembrane transport
GPA07_14135	COG4166	transmembrane transport
GPA07_14140	COG0180	Tryptophanyl-tRNA synthetase
GPA07_14175	COG4608	Belongs to the ABC transporter superfamily
GPA07_14180	COG0444	Belongs to the ABC transporter superfamily
GPA07_14185	COG5504	Zn-dependent protease
GPA07_14190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPA07_14195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPA07_14210	COG1744	ABC transporter substrate-binding protein PnrA-like
GPA07_14220	COG2267	carboxylic ester hydrolase activity
GPA07_14235	COG2814	Major facilitator Superfamily
GPA07_14245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPA07_14250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPA07_14255	COG0505	Belongs to the CarA family
GPA07_14260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPA07_14265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPA07_14275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPA07_14280	COG2271	Major facilitator Superfamily
GPA07_14285	COG0277	FAD linked oxidase domain protein
GPA07_14290	COG2151	metal-sulfur cluster biosynthetic enzyme
GPA07_14295	COG1073	alpha beta
GPA07_14300	COG0561	phosphatase activity
GPA07_14320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPA07_14325	COG1307	EDD domain protein, DegV family
GPA07_14330	COG0840	transmembrane signaling receptor activity
GPA07_14340	COG2996	Protein conserved in bacteria
GPA07_14345	COG1666	GTP binding
GPA07_14350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPA07_14350	COG0646	methionine synthase
GPA07_14355	COG0646	methionine synthase
GPA07_14355	COG1410	methionine synthase
GPA07_14395	COG0076	glutamate decarboxylase activity
GPA07_14420	COG1917	Cupin 2, conserved barrel domain protein
GPA07_14420	COG2207	Transcriptional regulator
GPA07_14425	COG0534	Mate efflux family protein
GPA07_14430	COG1562	ergosterol biosynthetic process
GPA07_14445	COG0367	asparagine synthase
GPA07_14460	COG0179	Fumarylacetoacetate (FAA) hydrolase
GPA07_14470	COG5337	Spore coat protein CotH
GPA07_14510	COG1403	HNH endonuclease
GPA07_14515	COG0419	ATPase involved in DNA repair
GPA07_14520	COG0420	3'-5' exonuclease activity
GPA07_14525	COG1074	ATP-dependent DNA helicase activity
GPA07_14530	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GPA07_14535	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GPA07_14540	COG2259	Doxx family
GPA07_14545	COG0501	Belongs to the peptidase M48B family
GPA07_14555	COG3180	Ammonia monooxygenase
GPA07_14560	COG0681	Belongs to the peptidase S26 family
GPA07_14565	COG0398	Pfam SNARE associated Golgi protein
GPA07_14580	COG1316	TRANSCRIPTIONal
GPA07_14585	COG4607	ABC-type enterochelin transport system periplasmic component
GPA07_14590	COG4604	ABC transporter, ATP-binding protein
GPA07_14595	COG4605	iron ion homeostasis
GPA07_14600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA07_14605	COG2732	(Barnase) inhibitor
GPA07_14610	COG2814	Major facilitator Superfamily
GPA07_14615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPA07_14630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPA07_14635	COG2964	Protein conserved in bacteria
GPA07_14640	COG4903	ComK protein
GPA07_14650	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_14655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPA07_14655	COG0723	plastoquinol--plastocyanin reductase activity
GPA07_14660	COG0840	transmembrane signaling receptor activity
GPA07_14665	COG0406	alpha-ribazole phosphatase activity
GPA07_14670	COG1404	Belongs to the peptidase S8 family
GPA07_14675	COG0501	Belongs to the peptidase M48B family
GPA07_14685	COG0318	PFAM AMP-dependent synthetase and ligase
GPA07_14690	COG0095	Lipoate-protein ligase
GPA07_14695	COG1234	tRNA 3'-trailer cleavage
GPA07_14705	COG1301	dicarboxylic acid transport
GPA07_14710	COG1363	Peptidase, m42
GPA07_14715	COG1511	domain protein
GPA07_14720	COG1309	transcriptional regulator
GPA07_14735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPA07_14740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPA07_14745	COG2329	Antibiotic biosynthesis monooxygenase
GPA07_14755	COG1473	amidohydrolase
GPA07_14765	COG4473	ABC transporter
GPA07_14770	COG1131	(ABC) transporter
GPA07_14775	COG0537	adenosine 5'-monophosphoramidase activity
GPA07_14780	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPA07_14800	COG1846	Transcriptional regulator
GPA07_14830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPA07_14840	COG3481	metal-dependent phosphohydrolase, HD sub domain
GPA07_14845	COG4717	serine-type aminopeptidase activity
GPA07_14850	COG0420	3'-5' exonuclease activity
GPA07_14860	COG1024	Enoyl-CoA hydratase
GPA07_14865	COG0490	domain, Protein
GPA07_14870	COG0475	glutathione-regulated potassium exporter activity
GPA07_14880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPA07_14885	COG0561	phosphatase activity
GPA07_14890	COG3679	Belongs to the UPF0342 family
GPA07_14895	COG4399	Belongs to the UPF0754 family
GPA07_14900	COG0189	ligase activity
GPA07_14915	COG2508	Transcriptional regulator
GPA07_14920	COG3842	ATPase activity
GPA07_14930	COG0702	epimerase
GPA07_14940	COG1132	(ABC) transporter
GPA07_14945	COG1132	(ABC) transporter
GPA07_14950	COG0589	response to stress
GPA07_14955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPA07_14960	COG0726	polysaccharide deacetylase
GPA07_14965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPA07_14970	COG0668	transmembrane transport
GPA07_14980	COG0584	glycerophosphoryl diester phosphodiesterase
GPA07_14985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPA07_15000	COG1253	flavin adenine dinucleotide binding
GPA07_15005	COG0789	Transcriptional regulator
GPA07_15010	COG1253	flavin adenine dinucleotide binding
GPA07_15015	COG0204	Acyl-transferase
GPA07_15020	COG1595	DNA-templated transcription, initiation
GPA07_15035	COG0531	amino acid
GPA07_15040	COG0791	NLP P60 protein
GPA07_15040	COG1388	LysM domain
GPA07_15045	COG1785	Belongs to the alkaline phosphatase family
GPA07_15050	COG2719	SpoVR family
GPA07_15055	COG1017	nitric oxide dioxygenase activity
GPA07_15055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPA07_15060	COG1959	2 iron, 2 sulfur cluster binding
GPA07_15065	COG0753	catalase activity
GPA07_15080	COG2197	response regulator
GPA07_15085	COG4585	Histidine kinase
GPA07_15085	COG2203	Gaf domain
GPA07_15090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPA07_15095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPA07_15100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPA07_15105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPA07_15110	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GPA07_15115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPA07_15120	COG3835	regulator
GPA07_15140	COG3153	acetyltransferase
GPA07_15140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPA07_15145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPA07_15155	COG0564	pseudouridine synthase activity
GPA07_15160	COG3764	Sortase (surface protein transpeptidase)
GPA07_15165	COG4085	toxin activity
GPA07_15165	COG1525	nuclease
GPA07_15165	COG0737	Belongs to the 5'-nucleotidase family
GPA07_15170	COG5002	protein histidine kinase activity
GPA07_15175	COG5577	PFAM Coat F domain
GPA07_15200	COG3706	GGDEF domain
GPA07_15205	COG1278	Cold shock
GPA07_15215	COG0655	NAD(P)H dehydrogenase (quinone) activity
GPA07_15220	COG2814	Major facilitator Superfamily
GPA07_15225	COG1566	PFAM secretion protein HlyD family protein
GPA07_15230	COG2718	Belongs to the UPF0229 family
GPA07_15235	COG2766	serine protein kinase
GPA07_15240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPA07_15250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPA07_15255	COG3382	B3 4 domain protein
GPA07_15285	COG1131	(ABC) transporter
GPA07_15295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPA07_15300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPA07_15305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPA07_15310	COG1116	anion transmembrane transporter activity
GPA07_15325	COG0681	Belongs to the peptidase S26 family
GPA07_15330	COG1368	sulfuric ester hydrolase activity
GPA07_15475	COG0735	belongs to the Fur family
GPA07_15480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPA07_15485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPA07_15490	COG4129	membrane
GPA07_15505	COG0747	negative chemotaxis
GPA07_15510	COG4608	Belongs to the ABC transporter superfamily
GPA07_15515	COG0444	Belongs to the ABC transporter superfamily
GPA07_15520	COG1132	(ABC) transporter
GPA07_15525	COG3557	Belongs to the UPF0374 family
GPA07_15540	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_15550	COG1194	a g-specific adenine glycosylase
GPA07_15555	COG1988	membrane-bound metal-dependent
GPA07_15600	COG1191	sigma factor activity
GPA07_15610	COG2140	Oxalate decarboxylase
GPA07_15625	COG4485	Bacterial membrane protein, YfhO
GPA07_15630	COG0463	Glycosyl transferase, family 2
GPA07_15655	COG2137	regulation of response to DNA damage stimulus
GPA07_15660	COG1090	epimerase
GPA07_15675	COG0778	Nitroreductase
GPA07_15695	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPA07_15695	COG0392	lysyltransferase activity
GPA07_15700	COG1846	Transcriptional regulator
GPA07_15720	COG1742	UPF0060 membrane protein
GPA07_15725	COG1132	(ABC) transporter
GPA07_15735	COG2207	Transcriptional regulator
GPA07_15735	COG1917	Cupin 2, conserved barrel domain protein
GPA07_15740	COG0492	ferredoxin-NADP+ reductase activity
GPA07_15745	COG2755	lipolytic protein G-D-S-L family
GPA07_15750	COG4637	Psort location Cytoplasmic, score
GPA07_15760	COG1309	transcriptional regulator
GPA07_15765	COG2076	Multidrug Resistance protein
GPA07_15770	COG2076	Multidrug Resistance protein
GPA07_15830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPA07_15835	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPA07_15845	COG0598	Magnesium transport protein CorA
GPA07_15855	COG0726	polysaccharide deacetylase
GPA07_15865	COG0535	radical SAM domain protein
GPA07_15870	COG0668	transmembrane transport
GPA07_15875	COG0217	transcriptional regulatory protein
GPA07_15885	COG0387	Pfam Sodium calcium exchanger
GPA07_15895	COG0477	Major facilitator Superfamily
GPA07_15900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPA07_15905	COG1295	ribonuclease BN
GPA07_15910	COG4980	gas vesicle protein
GPA07_15915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPA07_15920	COG1115	amino acid carrier protein
GPA07_15925	COG4840	Belongs to the UPF0435 family
GPA07_15930	COG0693	protein deglycase activity
GPA07_15935	COG0737	Belongs to the 5'-nucleotidase family
GPA07_15945	COG2188	Transcriptional regulator
GPA07_15950	COG0366	Alpha amylase catalytic
GPA07_15955	COG1263	PTS System
GPA07_15955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA07_15970	COG0076	glutamate decarboxylase activity
GPA07_15975	COG1368	sulfuric ester hydrolase activity
GPA07_15990	COG1263	PTS System
GPA07_15990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA07_15995	COG0024	Methionine aminopeptidase
GPA07_16005	COG2258	MOSC domain
GPA07_16010	COG1254	Belongs to the acylphosphatase family
GPA07_16015	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GPA07_16030	COG2851	Citrate transporter
GPA07_16035	COG3181	Tripartite tricarboxylate transporter family receptor
GPA07_16040	COG4565	transcriptional regulatory protein
GPA07_16045	COG3290	protein histidine kinase activity
GPA07_16075	COG2130	NADP-dependent
GPA07_16080	COG0513	Belongs to the DEAD box helicase family
GPA07_16085	COG0488	(ABC) transporter
GPA07_16095	COG1469	GTP cyclohydrolase I activity
GPA07_16100	COG0488	(ABC) transporter
GPA07_16105	COG0463	Glycosyl transferase, family 2
GPA07_16105	COG0457	Tetratricopeptide repeat
GPA07_16110	COG0531	amino acid
GPA07_16125	COG0071	Belongs to the small heat shock protein (HSP20) family
GPA07_16140	COG0471	metal ion transport
GPA07_16150	COG2223	nitrite transmembrane transporter activity
GPA07_16155	COG1442	glycosyl transferase family 8
GPA07_16160	COG1216	Glycosyl transferase, family 2
GPA07_16165	COG1442	glycosyl transferase family 8
GPA07_16170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPA07_16175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GPA07_16205	COG2211	Major facilitator Superfamily
GPA07_16215	COG1486	melibiose metabolic process
GPA07_16240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPA07_16245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPA07_16250	COG1597	lipid kinase activity
GPA07_16255	COG1957	nucleoside hydrolase
GPA07_16260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPA07_16265	COG1309	transcriptional regulator
GPA07_16270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPA07_16275	COG0154	amidase activity
GPA07_16280	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPA07_16285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPA07_16290	COG1285	pathogenesis
GPA07_16295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPA07_16300	COG4851	CamS sex pheromone cAM373 precursor
GPA07_16305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPA07_16310	COG0210	DNA helicase
GPA07_16315	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GPA07_16325	COG0069	glutamate synthase activity
GPA07_16330	COG4496	protein, YerC YecD
GPA07_16335	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GPA07_16345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPA07_16350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GPA07_16355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GPA07_16360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPA07_16380	COG0151	Belongs to the GarS family
GPA07_16385	COG0138	bifunctional purine biosynthesis protein purh
GPA07_16390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPA07_16395	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPA07_16400	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPA07_16405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPA07_16410	COG0047	phosphoribosylformylglycinamidine synthase activity
GPA07_16415	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPA07_16420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPA07_16425	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPA07_16430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPA07_16435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPA07_16445	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GPA07_16450	COG3064	Membrane
GPA07_16455	COG5583	Uncharacterized small protein (DUF2292)
GPA07_16460	COG2252	PERMEase
GPA07_16465	COG0583	DNA-binding transcription factor activity
GPA07_16470	COG2814	Major facilitator Superfamily
GPA07_16480	COG1595	DNA-templated transcription, initiation
GPA07_16525	COG1192	Involved in chromosome partitioning
GPA07_16530	COG0519	Catalyzes the synthesis of GMP from XMP
GPA07_16530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPA07_16535	COG1305	Transglutaminase-like
GPA07_16540	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GPA07_16545	COG0714	Associated with various cellular activities
GPA07_16550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPA07_16555	COG1113	amino acid transport
GPA07_16560	COG2132	Multicopper oxidase
GPA07_16570	COG0823	Involved in the tonB-independent uptake of proteins
GPA07_16575	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPA07_16595	COG0459	protein refolding
GPA07_16600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPA07_16605	COG1266	CAAX protease self-immunity
GPA07_16620	COG0805	protein transport
GPA07_16625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPA07_16630	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GPA07_16635	COG0315	cyclic pyranopterin monophosphate synthase activity
GPA07_16640	COG0488	(ABC) transporter
GPA07_16645	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPA07_16650	COG0456	acetyltransferase
GPA07_16655	COG1214	PFAM Peptidase M22, glycoprotease
GPA07_16660	COG0802	atpase or kinase
GPA07_16665	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPA07_16705	COG1301	dicarboxylic acid transport
GPA07_16715	COG0697	spore germination
GPA07_16720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GPA07_16750	COG1396	sequence-specific DNA binding
GPA07_16765	COG0778	Nitroreductase
GPA07_16770	COG1846	Transcriptional regulator
GPA07_16775	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPA07_16805	COG2814	Major facilitator Superfamily
GPA07_16825	COG0252	asparaginase activity
GPA07_16835	COG0477	Major facilitator Superfamily
GPA07_16850	COG1329	Transcriptional regulator
GPA07_16855	COG1278	Cold shock
GPA07_16905	COG3284	Transcriptional regulator
GPA07_16910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPA07_16915	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPA07_16920	COG0022	dehydrogenase e1 component
GPA07_16925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GPA07_16930	COG3091	SprT-like family
GPA07_16940	COG2183	response to ionizing radiation
GPA07_16945	COG2208	phosphoserine phosphatase activity
GPA07_16950	COG1191	sigma factor activity
GPA07_16955	COG2172	sigma factor antagonist activity
GPA07_16960	COG1366	Belongs to the anti-sigma-factor antagonist family
GPA07_16965	COG2208	phosphoserine phosphatase activity
GPA07_16970	COG2172	sigma factor antagonist activity
GPA07_16975	COG1366	Belongs to the anti-sigma-factor antagonist family
GPA07_16980	COG1366	Belongs to the anti-sigma-factor antagonist family
GPA07_16985	COG2337	Toxic component of a toxin-antitoxin (TA) module
GPA07_16990	COG0864	Transcriptional regulator
GPA07_16995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPA07_17000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GPA07_17005	COG0736	holo-[acyl-carrier-protein] synthase activity
GPA07_17010	COG0705	Rhomboid family
GPA07_17015	COG3428	Bacterial PH domain
GPA07_17020	COG3402	PFAM membrane-flanked domain
GPA07_17025	COG0513	Belongs to the DEAD box helicase family
GPA07_17040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPA07_17045	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPA07_17050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPA07_17065	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GPA07_17070	COG1131	(ABC) transporter
GPA07_17075	COG1301	dicarboxylic acid transport
GPA07_17080	COG0628	permease
GPA07_17085	COG1301	dicarboxylic acid transport
GPA07_17090	COG4565	transcriptional regulatory protein
GPA07_17095	COG3290	protein histidine kinase activity
GPA07_17100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPA07_17105	COG2217	Heavy metal translocating P-type atpase
GPA07_17110	COG2261	transglycosylase associated protein
GPA07_17115	COG1914	H( )-stimulated, divalent metal cation uptake system
GPA07_17150	COG0028	Belongs to the TPP enzyme family
GPA07_17155	COG0531	amino acid
GPA07_17165	COG1215	transferase activity, transferring glycosyl groups
GPA07_17170	COG5298	Protein conserved in bacteria
GPA07_17175	COG3706	GGDEF domain
GPA07_17180	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GPA07_17185	COG0551	DNA topoisomerase type I activity
GPA07_17185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPA07_17190	COG2814	Major facilitator Superfamily
GPA07_17210	COG3871	stress protein (general stress protein 26)
GPA07_17215	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_17220	COG2226	methyltransferase
GPA07_17225	COG3711	transcriptional antiterminator
GPA07_17235	COG2755	lipolytic protein G-D-S-L family
GPA07_17240	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPA07_17245	COG1414	Transcriptional regulator
GPA07_17250	COG1984	allophanate hydrolase subunit 2
GPA07_17255	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GPA07_17260	COG4336	lyase activity
GPA07_17265	COG1914	H( )-stimulated, divalent metal cation uptake system
GPA07_17270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPA07_17275	COG0561	phosphatase activity
GPA07_17285	COG0346	lactoylglutathione lyase activity
GPA07_17320	COG0246	Mannitol dehydrogenase
GPA07_17325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA07_17330	COG2213	PTS system mannitol-specific
GPA07_17335	COG1276	copper resistance
GPA07_17335	COG2372	response to copper ion
GPA07_17340	COG4549	nuclear export factor GLE1
GPA07_17345	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPA07_17350	COG1012	belongs to the aldehyde dehydrogenase family
GPA07_17355	COG0531	amino acid
GPA07_17360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPA07_17365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPA07_17370	COG0583	DNA-binding transcription factor activity
GPA07_17380	COG0640	Transcriptional regulator
GPA07_17385	COG1309	transcriptional regulator
GPA07_17390	COG2814	Major facilitator Superfamily
GPA07_17395	COG0527	aspartate kinase activity
GPA07_17400	COG1366	Belongs to the anti-sigma-factor antagonist family
GPA07_17405	COG3850	Histidine kinase
GPA07_17405	COG5002	protein histidine kinase activity
GPA07_17410	COG0745	RESPONSE REGULATOR receiver
GPA07_17440	COG2079	MmgE PrpD family protein
GPA07_17450	COG1126	abc transporter atp-binding protein
GPA07_17455	COG0765	amino acid transport
GPA07_17460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA07_17475	COG5434	Belongs to the glycosyl hydrolase 28 family
GPA07_17480	COG3104	oligopeptide transport
GPA07_17490	COG1121	(ABC) transporter
GPA07_17505	COG0833	amino acid
GPA07_17515	COG2814	Major facilitator Superfamily
GPA07_17520	COG0412	Dienelactone hydrolase
GPA07_17530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA07_17535	COG0765	amino acid transport
GPA07_17540	COG1126	abc transporter atp-binding protein
GPA07_17545	COG2002	toxin-antitoxin pair type II binding
GPA07_17550	COG3764	Sortase (surface protein transpeptidase)
GPA07_17560	COG2364	Membrane
GPA07_17580	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GPA07_17585	COG0300	oxidoreductase activity
GPA07_17585	COG0318	PFAM AMP-dependent synthetase and ligase
GPA07_17585	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_17585	COG3321	synthase
GPA07_17585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPA07_17595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPA07_17600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPA07_17605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPA07_17615	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPA07_17640	COG3209	COG3209 Rhs family protein
GPA07_17645	COG3290	protein histidine kinase activity
GPA07_17645	COG0840	transmembrane signaling receptor activity
GPA07_17655	COG2746	aminoglycoside 3-N-acetyltransferase activity
GPA07_17660	COG1522	sequence-specific DNA binding
GPA07_17665	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GPA07_17675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA07_17680	COG0765	amino acid transport
GPA07_17685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPA07_17690	COG2508	Transcriptional regulator
GPA07_17695	COG1012	belongs to the aldehyde dehydrogenase family
GPA07_17700	COG0506	proline dehydrogenase activity
GPA07_17705	COG3541	Predicted nucleotidyltransferase
GPA07_17715	COG3458	cephalosporin-C deacetylase activity
GPA07_17720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPA07_17725	COG0583	DNA-binding transcription factor activity
GPA07_17730	COG2226	methyltransferase
GPA07_17735	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPA07_17740	COG1414	Transcriptional regulator
GPA07_17750	COG2271	Major facilitator Superfamily
GPA07_17755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GPA07_17765	COG0028	Belongs to the TPP enzyme family
GPA07_17770	COG0710	3-dehydroquinate dehydratase activity
GPA07_17775	COG1012	belongs to the aldehyde dehydrogenase family
GPA07_17785	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPA07_17790	COG3665	Urea carboxylase-associated protein
GPA07_17795	COG1113	amino acid transport
GPA07_17800	COG3403	YqcI/YcgG family
GPA07_17810	COG1280	lysine exporter protein (LysE YggA)
GPA07_17825	COG0561	phosphatase activity
GPA07_17830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPA07_17835	COG1609	Transcriptional regulator
GPA07_17840	COG1620	l-lactate permease
GPA07_17845	COG0039	L-malate dehydrogenase activity
GPA07_17860	COG2113	Glycine betaine
GPA07_17865	COG4176	ABC-type proline glycine betaine transport system permease component
GPA07_17870	COG4175	Glycine betaine
GPA07_17870	COG0517	IMP dehydrogenase activity
GPA07_17875	COG3853	Toxic anion resistance protein (TelA)
GPA07_17905	COG0861	Integral membrane protein TerC family
GPA07_17910	COG2310	stress, protein
GPA07_17915	COG2310	stress, protein
GPA07_17920	COG2310	stress, protein
GPA07_17925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPA07_17935	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_17940	COG3773	Cell wall hydrolase
GPA07_17975	COG1668	transmembrane transport
GPA07_17980	COG4555	ABC transporter
GPA07_17985	COG3279	Response regulator of the LytR AlgR family
GPA07_17990	COG3290	protein histidine kinase activity
GPA07_17995	COG0667	Aldo Keto reductase
GPA07_18005	COG1405	negative regulation of cell septum assembly
GPA07_18005	COG3012	SEC-C Motif Domain Protein
GPA07_18010	COG0784	Response regulator, receiver
GPA07_18015	COG4191	Histidine kinase
GPA07_18020	COG2066	Belongs to the glutaminase family
GPA07_18025	COG1115	amino acid carrier protein
GPA07_18030	COG0596	Alpha beta hydrolase
GPA07_18040	COG0531	amino acid
GPA07_18045	COG0318	PFAM AMP-dependent synthetase and ligase
GPA07_18050	COG1846	Transcriptional regulator
GPA07_18055	COG1917	Cupin 2, conserved barrel domain protein
GPA07_18060	COG1309	transcriptional regulator
GPA07_18070	COG1404	Belongs to the peptidase S8 family
GPA07_18090	COG2814	Major facilitator Superfamily
GPA07_18110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPA07_18115	COG2040	homocysteine
GPA07_18120	COG0833	amino acid
GPA07_18130	COG1404	Belongs to the peptidase S8 family
GPA07_18135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA07_18135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA07_18140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPA07_18145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPA07_18150	COG0383	alpha-mannosidase activity
GPA07_18155	COG1940	carbohydrate kinase activity
GPA07_18160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA07_18160	COG3711	transcriptional antiterminator
GPA07_18180	COG0531	amino acid
GPA07_18190	COG0371	Dehydrogenase
GPA07_18205	COG0656	L-ascorbic acid biosynthetic process
GPA07_18210	COG1683	Conserved Protein
GPA07_18220	COG1846	Transcriptional regulator
GPA07_18235	COG2814	Major facilitator Superfamily
GPA07_18240	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPA07_18245	COG0730	response to heat
GPA07_18250	COG0425	Belongs to the sulfur carrier protein TusA family
GPA07_18255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPA07_18255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPA07_18260	COG0425	Belongs to the sulfur carrier protein TusA family
GPA07_18260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPA07_18270	COG2210	Belongs to the sulfur carrier protein TusA family
GPA07_18275	COG1937	Protein conserved in bacteria
GPA07_18305	COG1131	(ABC) transporter
GPA07_18320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPA07_18330	COG1331	Highly conserved protein containing a thioredoxin domain
GPA07_18335	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPA07_18345	COG1331	Highly conserved protein containing a thioredoxin domain
GPA07_18350	COG1331	Highly conserved protein containing a thioredoxin domain
GPA07_18360	COG2271	Major facilitator Superfamily
GPA07_18365	COG0584	glycerophosphoryl diester phosphodiesterase
GPA07_18370	COG1113	amino acid transport
GPA07_18395	COG2814	Major facilitator Superfamily
GPA07_18400	COG2311	Membrane
GPA07_18415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPA07_18420	COG1413	lyase activity
GPA07_18430	COG1131	(ABC) transporter
GPA07_18455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GPA07_18460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPA07_18465	COG4856	YbbR-like protein
GPA07_18470	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPA07_18475	COG5662	AntiSigma factor
GPA07_18480	COG1595	DNA-templated transcription, initiation
GPA07_18515	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPA07_18520	COG1737	Transcriptional regulator
GPA07_18525	COG1263	PTS System
GPA07_18525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA07_18530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GPA07_18535	COG1472	Belongs to the glycosyl hydrolase 3 family
GPA07_18540	COG3876	Protein conserved in bacteria
GPA07_18545	COG0385	Bile acid
GPA07_18550	COG2271	Major facilitator Superfamily
GPA07_18555	COG1028	Short-chain dehydrogenase reductase Sdr
GPA07_18560	COG1063	alcohol dehydrogenase