locus-tag	class	description
BKP58_00020	COG2211	Major facilitator Superfamily
BKP58_00030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKP58_00040	COG0456	acetyltransferase
BKP58_00045	COG2329	Antibiotic biosynthesis monooxygenase
BKP58_00050	COG0456	acetyltransferase
BKP58_00050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BKP58_00055	COG4918	Iron-sulphur cluster biosynthesis
BKP58_00065	COG1073	alpha beta
BKP58_00075	COG0667	Aldo Keto reductase
BKP58_00085	COG0494	nUDIX hydrolase
BKP58_00090	COG1379	DNA repair
BKP58_00095	COG1396	sequence-specific DNA binding
BKP58_00100	COG0252	asparaginase activity
BKP58_00105	COG1027	Aspartate ammonia-lyase
BKP58_00110	COG1757	Na H antiporter
BKP58_00115	COG0281	malic enzyme
BKP58_00125	COG1300	Membrane
BKP58_00130	COG0735	belongs to the Fur family
BKP58_00140	COG4974	Belongs to the 'phage' integrase family
BKP58_00145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BKP58_00150	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BKP58_00155	COG1686	Belongs to the peptidase S11 family
BKP58_00160	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP58_00165	COG2172	sigma factor antagonist activity
BKP58_00170	COG1191	sigma factor activity
BKP58_00190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKP58_00205	COG0697	spore germination
BKP58_00210	COG0019	diaminopimelate decarboxylase activity
BKP58_00215	COG4086	secreted protein
BKP58_00225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKP58_00275	COG3328	transposase activity
BKP58_00305	COG2433	Pfam Transposase IS66
BKP58_00320	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BKP58_00330	COG0681	Belongs to the peptidase S26 family
BKP58_00340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKP58_00340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKP58_00345	COG0307	riboflavin synthase, alpha
BKP58_00350	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKP58_00350	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKP58_00355	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BKP58_00360	COG0456	acetyltransferase
BKP58_00365	COG1547	Domain of unknown function (DUF309)
BKP58_00370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BKP58_00375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKP58_00385	COG1686	Belongs to the peptidase S11 family
BKP58_00390	COG2715	membrane protein required for spore maturation
BKP58_00395	COG0700	Nucleoside recognition
BKP58_00400	COG1187	pseudouridine synthase activity
BKP58_00405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP58_00410	COG1333	cytochrome c biogenesis protein
BKP58_00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKP58_00420	COG0745	RESPONSE REGULATOR receiver
BKP58_00425	COG5002	protein histidine kinase activity
BKP58_00430	COG1595	DNA-templated transcription, initiation
BKP58_00440	COG0710	3-dehydroquinate dehydratase activity
BKP58_00445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKP58_00450	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BKP58_00455	COG1141	Ferredoxin
BKP58_00460	COG4955	Helix-turn-helix domain
BKP58_00465	COG0514	ATP-dependent DNA helicase (RecQ)
BKP58_00475	COG1388	LysM domain
BKP58_00485	COG1408	metallophosphoesterase
BKP58_00490	COG4862	establishment of competence for transformation
BKP58_00495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKP58_00500	COG0492	ferredoxin-NADP+ reductase activity
BKP58_00505	COG2339	peptidase activity
BKP58_00510	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_00510	COG3773	Cell wall hydrolase
BKP58_00515	COG2959	enzyme of heme biosynthesis
BKP58_00520	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BKP58_00530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKP58_00535	COG0539	negative regulation of cytoplasmic translation
BKP58_00540	COG1304	FMN binding
BKP58_00565	COG1160	GTP binding
BKP58_00570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKP58_00585	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BKP58_00590	COG0776	regulation of translation
BKP58_00595	COG0302	gtp cyclohydrolase
BKP58_00605	COG0142	geranyltranstransferase activity
BKP58_00610	COG2226	methyltransferase
BKP58_00615	COG0142	geranyltranstransferase activity
BKP58_00620	COG0105	UTP biosynthetic process
BKP58_00630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BKP58_00635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKP58_00640	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKP58_00645	COG4401	Chorismate mutase type I
BKP58_00650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKP58_00655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKP58_00665	COG0135	phosphoribosylanthranilate isomerase activity
BKP58_00670	COG0133	tryptophan synthase activity
BKP58_00685	COG0287	Prephenate dehydrogenase
BKP58_00690	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKP58_00695	COG0457	Tetratricopeptide repeat
BKP58_00700	COG5582	Belongs to the UPF0302 family
BKP58_00710	COG0723	plastoquinol--plastocyanin reductase activity
BKP58_00715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKP58_00720	COG2010	Cytochrome c
BKP58_00720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKP58_00725	COG4347	Protein of unknown function (DUF1405)
BKP58_00735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP58_00740	COG1694	Mazg nucleotide pyrophosphohydrolase
BKP58_00745	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKP58_00750	COG1803	Methylglyoxal synthase
BKP58_00755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKP58_00760	COG0438	transferase activity, transferring glycosyl groups
BKP58_00765	COG0617	tRNA 3'-terminal CCA addition
BKP58_00770	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BKP58_00770	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BKP58_00775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKP58_00780	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKP58_00785	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BKP58_00790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BKP58_00790	COG1199	ATP-dependent helicase activity
BKP58_00800	COG5353	protein conserved in bacteria
BKP58_00805	COG0436	Aminotransferase
BKP58_00810	COG0017	Asparaginyl-tRNA synthetase
BKP58_00815	COG3935	DnaD domain protein
BKP58_00820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKP58_00830	COG4499	WXG100 protein secretion system (Wss), protein YukC
BKP58_00830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP58_00835	COG3331	DNA recombination
BKP58_00870	COG0071	Belongs to the small heat shock protein (HSP20) family
BKP58_00875	COG2190	(PTS) system
BKP58_00880	COG1111	helicase
BKP58_00880	COG1205	dead DEAH box helicase
BKP58_00885	COG3359	exonuclease
BKP58_00895	COG4474	Belongs to the UPF0398 family
BKP58_00910	COG0116	Belongs to the methyltransferase superfamily
BKP58_00920	COG1199	ATP-dependent helicase activity
BKP58_00925	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_00930	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BKP58_00935	COG1609	Transcriptional regulator
BKP58_00940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP58_00945	COG0800	Aldolase
BKP58_00955	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BKP58_00960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKP58_00965	COG2233	PERMEase
BKP58_00970	COG3424	synthase
BKP58_00975	COG1755	Isoprenylcysteine carboxyl methyltransferase
BKP58_00980	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BKP58_01000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKP58_01010	COG0328	RNA-DNA hybrid ribonuclease activity
BKP58_01015	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BKP58_01020	COG0328	RNA-DNA hybrid ribonuclease activity
BKP58_01040	COG1278	Cold shock
BKP58_01045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKP58_01050	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BKP58_01055	COG0386	Belongs to the glutathione peroxidase family
BKP58_01060	COG1418	mRNA catabolic process
BKP58_01065	COG1413	lyase activity
BKP58_01070	COG0129	dihydroxy-acid dehydratase activity
BKP58_01080	COG2136	Putative SAM-dependent methyltransferase
BKP58_01080	COG2521	methyltransferase
BKP58_01090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BKP58_01095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKP58_01100	COG0204	Acyl-transferase
BKP58_01105	COG1272	protein, Hemolysin III
BKP58_01110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BKP58_01115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKP58_01130	COG1999	signal sequence binding
BKP58_01135	COG2755	lipolytic protein G-D-S-L family
BKP58_01140	COG4698	Protein conserved in bacteria
BKP58_01150	COG0534	Mate efflux family protein
BKP58_01155	COG1846	Transcriptional regulator
BKP58_01160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP58_01165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP58_01170	COG1086	Polysaccharide biosynthesis protein
BKP58_01175	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BKP58_01180	COG4641	Protein conserved in bacteria
BKP58_01195	COG0463	Glycosyl transferase, family 2
BKP58_01200	COG0456	acetyltransferase
BKP58_01215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKP58_01220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BKP58_01225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BKP58_01230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKP58_01235	COG0456	acetyltransferase
BKP58_01240	COG1509	lysine 2,3-aminomutase activity
BKP58_01250	COG4479	Belongs to the UPF0346 family
BKP58_01275	COG0671	phosphoesterase, PA-phosphatase related
BKP58_01290	COG0813	purine-nucleoside phosphorylase activity
BKP58_01295	COG1876	peptidase activity
BKP58_01305	COG2226	methyltransferase
BKP58_01310	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_01310	COG0793	Belongs to the peptidase S41A family
BKP58_01315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP58_01330	COG0400	carboxylic ester hydrolase activity
BKP58_01335	COG2801	Transposase and inactivated derivatives
BKP58_01345	COG0778	Nitroreductase
BKP58_01350	COG1733	regulation of RNA biosynthetic process
BKP58_01355	COG1942	4-Oxalocrotonate Tautomerase
BKP58_01375	COG2962	Rard protein
BKP58_01385	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKP58_01390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKP58_01395	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP58_01400	COG0534	Mate efflux family protein
BKP58_01405	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BKP58_01410	COG1819	glycosyl
BKP58_01415	COG0791	NLP P60 protein
BKP58_01415	COG1388	LysM domain
BKP58_01420	COG2032	superoxide dismutase activity
BKP58_01425	COG0714	Associated with various cellular activities
BKP58_01430	COG4548	von Willebrand factor, type A
BKP58_01435	COG0567	Dehydrogenase, E1 component
BKP58_01440	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKP58_01445	COG0385	Bile acid
BKP58_01450	COG0733	neurotransmitter:sodium symporter activity
BKP58_01455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKP58_01460	COG1657	PFAM Prenyltransferase squalene oxidase
BKP58_01465	COG1012	belongs to the aldehyde dehydrogenase family
BKP58_01490	COG0071	Belongs to the small heat shock protein (HSP20) family
BKP58_01505	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKP58_01510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKP58_01525	COG0514	ATP-dependent DNA helicase (RecQ)
BKP58_01530	COG1388	LysM domain
BKP58_01530	COG3584	3D domain protein
BKP58_01535	COG2197	response regulator
BKP58_01540	COG4585	Histidine kinase
BKP58_01545	COG3239	Fatty acid desaturase
BKP58_01550	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKP58_01565	COG2322	membrane
BKP58_01570	COG0741	lytic transglycosylase activity
BKP58_01575	COG0640	Transcriptional regulator
BKP58_01585	COG2378	regulation of single-species biofilm formation
BKP58_01590	COG3708	Transcriptional regulator
BKP58_01595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP58_01600	COG1309	transcriptional regulator
BKP58_01605	COG0456	acetyltransferase
BKP58_01610	COG2207	Transcriptional regulator
BKP58_01610	COG0662	Cupin 2, conserved barrel domain protein
BKP58_01615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP58_01620	COG1231	oxidoreductase activity
BKP58_01625	COG4282	regulation of fungal-type cell wall biogenesis
BKP58_01630	COG5444	nuclease activity
BKP58_01650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP58_01675	COG3328	transposase activity
BKP58_01685	COG2211	Major facilitator Superfamily
BKP58_01690	COG2226	methyltransferase
BKP58_01695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKP58_01750	COG3328	transposase activity
BKP58_01770	COG2801	Transposase and inactivated derivatives
BKP58_01795	COG3328	transposase activity
BKP58_01800	COG2814	Major facilitator Superfamily
BKP58_01810	COG1131	(ABC) transporter
BKP58_01825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP58_01835	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BKP58_01840	COG0300	oxidoreductase activity
BKP58_01865	COG0583	DNA-binding transcription factor activity
BKP58_01870	COG0069	glutamate synthase activity
BKP58_01870	COG0067	glutamate synthase
BKP58_01870	COG0070	glutamate synthase
BKP58_01875	COG0493	'glutamate synthase
BKP58_01880	COG0604	alcohol dehydrogenase
BKP58_01885	COG0583	DNA-binding transcription factor activity
BKP58_01890	COG0405	Gamma-glutamyltransferase
BKP58_01895	COG0166	Belongs to the GPI family
BKP58_01900	COG0582	viral genome integration into host DNA
BKP58_01910	COG2801	Transposase and inactivated derivatives
BKP58_01925	COG0534	Mate efflux family protein
BKP58_01930	COG2017	converts alpha-aldose to the beta-anomer
BKP58_01935	COG2027	D-alanyl-D-alanine carboxypeptidase
BKP58_01940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKP58_01955	COG1649	PFAM Uncharacterised BCR, COG1649
BKP58_01965	COG1960	acyl-CoA dehydrogenase activity
BKP58_01970	COG0318	PFAM AMP-dependent synthetase and ligase
BKP58_01975	COG0439	Biotin carboxylase
BKP58_01980	COG0511	ligase activity, forming carbon-carbon bonds
BKP58_01985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP58_01990	COG1024	Enoyl-CoA hydratase
BKP58_01995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKP58_02000	COG2404	hydrolase activity, acting on ester bonds
BKP58_02005	COG0586	Pfam SNARE associated Golgi protein
BKP58_02010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKP58_02015	COG2246	polysaccharide biosynthetic process
BKP58_02025	COG5520	Belongs to the glycosyl hydrolase 30 family
BKP58_02035	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BKP58_02040	COG1115	amino acid carrier protein
BKP58_02055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKP58_02060	COG0187	DNA topoisomerase II activity
BKP58_02065	COG1832	CoA-binding protein
BKP58_02070	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKP58_02075	COG4841	protein insertion into membrane
BKP58_02085	COG0824	Thioesterase
BKP58_02105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP58_02110	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKP58_02125	COG0071	Belongs to the small heat shock protein (HSP20) family
BKP58_02135	COG4846	Membrane protein involved in cytochrome C biogenesis
BKP58_02140	COG2201	protein-glutamate methylesterase activity
BKP58_02145	COG0785	Cytochrome C biogenesis protein
BKP58_02155	COG3763	UPF0154 protein
BKP58_02165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BKP58_02170	COG4224	UPF0291 protein
BKP58_02175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKP58_02180	COG1388	LysM domain
BKP58_02185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKP58_02195	COG0346	lactoylglutathione lyase activity
BKP58_02205	COG4195	phage-related replication protein
BKP58_02250	COG3832	glyoxalase III activity
BKP58_02270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKP58_02310	COG0756	dUTP diphosphatase activity
BKP58_02325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKP58_02330	COG2814	Major facilitator Superfamily
BKP58_02335	COG1525	nuclease
BKP58_02340	COG3328	transposase activity
BKP58_02345	COG1070	Carbohydrate kinase
BKP58_02350	COG2115	Belongs to the xylose isomerase family
BKP58_02355	COG1940	carbohydrate kinase activity
BKP58_02360	COG3507	Belongs to the glycosyl hydrolase 43 family
BKP58_02375	COG2211	Major facilitator Superfamily
BKP58_02380	COG0135	phosphoribosylanthranilate isomerase activity
BKP58_02405	COG3655	Transcriptional regulator
BKP58_02420	COG3328	transposase activity
BKP58_02440	COG4282	regulation of fungal-type cell wall biogenesis
BKP58_02475	COG5444	nuclease activity
BKP58_02485	COG1388	LysM domain
BKP58_02485	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_02485	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKP58_02525	COG5412	phage tail tape measure protein
BKP58_02525	COG3953	SLT domain
BKP58_02670	COG3645	SOS response
BKP58_02670	COG3646	Phage regulatory protein
BKP58_02690	COG4974	Belongs to the 'phage' integrase family
BKP58_02695	COG0174	glutamine synthetase
BKP58_02700	COG0789	Transcriptional regulator
BKP58_02705	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BKP58_02710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKP58_02720	COG0464	growth
BKP58_02725	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP58_02730	COG4112	unkown
BKP58_02735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKP58_02740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKP58_02745	COG1780	Probably involved in ribonucleotide reductase function
BKP58_02760	COG1923	regulation of RNA biosynthetic process
BKP58_02765	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BKP58_02780	COG2076	Multidrug Resistance protein
BKP58_02785	COG2076	Multidrug Resistance protein
BKP58_02790	COG1764	response to oxidative stress
BKP58_02795	COG4195	phage-related replication protein
BKP58_02805	COG1404	Belongs to the peptidase S8 family
BKP58_02810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP58_02820	COG3226	Transcriptional regulator
BKP58_02925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BKP58_02930	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BKP58_02940	COG4550	Control of competence regulator ComK, YlbF/YmcA
BKP58_02945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKP58_02950	COG0156	8-amino-7-oxononanoate synthase activity
BKP58_02955	COG1063	alcohol dehydrogenase
BKP58_02960	COG2359	stage V sporulation protein S
BKP58_02965	COG1692	metallophosphoesterase
BKP58_02970	COG1418	mRNA catabolic process
BKP58_02975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKP58_02980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKP58_02985	COG1058	Belongs to the CinA family
BKP58_02985	COG1546	Belongs to the CinA family
BKP58_02990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BKP58_02995	COG1426	Protein conserved in bacteria
BKP58_03010	COG0300	oxidoreductase activity
BKP58_03015	COG0612	Peptidase, M16
BKP58_03020	COG0612	Peptidase, M16
BKP58_03030	COG2188	Transcriptional regulator
BKP58_03035	COG4980	gas vesicle protein
BKP58_03035	COG1674	ftsk spoiiie
BKP58_03045	COG0740	serine-type endopeptidase activity
BKP58_03050	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BKP58_03055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP58_03060	COG0527	aspartate kinase activity
BKP58_03065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BKP58_03070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKP58_03075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP58_03085	COG1873	PFAM PRC-barrel domain
BKP58_03090	COG0612	Peptidase, M16
BKP58_03095	COG0726	polysaccharide deacetylase
BKP58_03100	COG1185	polyribonucleotide nucleotidyltransferase activity
BKP58_03105	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKP58_03110	COG0196	riboflavin kinase activity
BKP58_03115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BKP58_03120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BKP58_03125	COG1550	Protein conserved in bacteria
BKP58_03130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BKP58_03135	COG1358	cellular component organization or biogenesis
BKP58_03140	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BKP58_03145	COG0195	Participates in both transcription termination and antitermination
BKP58_03150	COG0779	Required for maturation of 30S ribosomal subunits
BKP58_03155	COG2176	DNA-directed DNA polymerase activity
BKP58_03160	COG0442	prolyl-tRNA aminoacylation
BKP58_03165	COG0750	zinc metalloprotease
BKP58_03170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BKP58_03175	COG4589	Belongs to the CDS family
BKP58_03180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKP58_03185	COG0233	cytoplasmic translational termination
BKP58_03190	COG0528	UMP kinase activity
BKP58_03195	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKP58_03200	COG0052	Belongs to the universal ribosomal protein uS2 family
BKP58_03210	COG1191	sigma factor activity
BKP58_03215	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BKP58_03225	COG0835	chemotaxis
BKP58_03230	COG0643	Histidine kinase
BKP58_03230	COG2198	Histidine kinase
BKP58_03235	COG2201	protein-glutamate methylesterase activity
BKP58_03240	COG0455	bacterial-type flagellum organization
BKP58_03245	COG1419	protein localization to endoplasmic reticulum
BKP58_03250	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKP58_03255	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKP58_03260	COG1684	flagellar biosynthetic protein fliR
BKP58_03265	COG1987	bacterial-type flagellum assembly
BKP58_03270	COG1338	Plays a role in the flagellum-specific transport system
BKP58_03275	COG3190	flagellar
BKP58_03280	COG2201	protein-glutamate methylesterase activity
BKP58_03285	COG1776	CheC inhibitor of MCP methylation
BKP58_03285	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKP58_03290	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKP58_03295	COG1580	Controls the rotational direction of flagella during chemotaxis
BKP58_03300	COG1582	Flagellar protein (FlbD)
BKP58_03305	COG4786	Flagellar basal body rod
BKP58_03310	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BKP58_03315	COG3144	bacterial-type flagellum assembly
BKP58_03320	COG3334	PFAM MgtE intracellular
BKP58_03325	COG2882	bacterial-type flagellum organization
BKP58_03330	COG1157	protein secretion by the type III secretion system
BKP58_03335	COG1317	bacterial-type flagellum organization
BKP58_03340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKP58_03350	COG1677	Flagellar hook-basal body complex protein FliE
BKP58_03355	COG1558	bacterial-type flagellum-dependent cell motility
BKP58_03360	COG1815	bacterial-type flagellum-dependent cell motility
BKP58_03365	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BKP58_03370	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BKP58_03375	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BKP58_03380	COG4974	Belongs to the 'phage' integrase family
BKP58_03385	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BKP58_03390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKP58_03395	COG0758	DNA mediated transformation
BKP58_03400	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BKP58_03405	COG0045	succinate-CoA ligase (ADP-forming) activity
BKP58_03410	COG2257	FlhB HrpN YscU SpaS Family
BKP58_03420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKP58_03425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BKP58_03430	COG0335	large ribosomal subunit rRNA binding
BKP58_03435	COG0336	Belongs to the RNA methyltransferase TrmD family
BKP58_03440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BKP58_03450	COG1837	Belongs to the UPF0109 family
BKP58_03455	COG0228	four-way junction DNA binding
BKP58_03460	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKP58_03465	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BKP58_03475	COG0552	protein localization to endoplasmic reticulum
BKP58_03480	COG1196	nuclear chromosome segregation
BKP58_03485	COG0571	ribonuclease III activity
BKP58_03490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKP58_03495	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_03500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKP58_03505	COG0416	fatty acid biosynthetic process
BKP58_03510	COG2050	protein possibly involved in aromatic compounds catabolism
BKP58_03510	COG1349	DNA-binding transcription factor activity
BKP58_03515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BKP58_03520	COG1760	l-serine dehydratase
BKP58_03525	COG1760	l-serine dehydratase
BKP58_03530	COG1461	Dihydroxyacetone kinase
BKP58_03535	COG1302	Protein conserved in bacteria
BKP58_03540	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKP58_03550	COG1564	THIamine pyrophosphokinase
BKP58_03555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BKP58_03560	COG1162	GTPase activity
BKP58_03565	COG2815	serine threonine protein kinase
BKP58_03565	COG0515	serine threonine protein kinase
BKP58_03570	COG0631	protein serine/threonine phosphatase activity
BKP58_03575	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKP58_03580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKP58_03580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BKP58_03585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKP58_03590	COG0242	peptide deformylase activity
BKP58_03595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKP58_03600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKP58_03605	COG1758	RNA polymerase activity
BKP58_03610	COG0194	GDP metabolic process
BKP58_03615	COG2052	Domain of unknown function (DUF370)
BKP58_03620	COG1561	YicC-like family, N-terminal region
BKP58_03625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKP58_03635	COG1648	precorrin-2 dehydrogenase activity
BKP58_03640	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BKP58_03645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKP58_03650	COG0529	Catalyzes the synthesis of activated sulfate
BKP58_03655	COG2046	Belongs to the sulfate adenylyltransferase family
BKP58_03660	COG0306	phosphate transporter
BKP58_03665	COG0175	sulfate reduction
BKP58_03670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKP58_03675	COG0284	orotidine-5'-phosphate decarboxylase activity
BKP58_03680	COG0167	dihydroorotate dehydrogenase activity
BKP58_03685	COG0543	2 iron, 2 sulfur cluster binding
BKP58_03690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKP58_03695	COG0505	Belongs to the CarA family
BKP58_03700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKP58_03705	COG0540	Belongs to the ATCase OTCase family
BKP58_03710	COG2233	PERMEase
BKP58_03715	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BKP58_03720	COG0564	pseudouridine synthase activity
BKP58_03725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKP58_03730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKP58_03735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKP58_03740	COG3599	regulation of cell shape
BKP58_03745	COG2302	S4 RNA-binding domain
BKP58_03750	COG0762	integral membrane protein
BKP58_03755	COG1799	cell septum assembly
BKP58_03760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BKP58_03770	COG1873	PFAM PRC-barrel domain
BKP58_03775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKP58_03780	COG1119	ATPase activity
BKP58_03785	COG1191	sigma factor activity
BKP58_03790	COG1191	sigma factor activity
BKP58_03800	COG1404	Belongs to the peptidase S8 family
BKP58_03800	COG4412	M6 family metalloprotease domain protein
BKP58_03805	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BKP58_03810	COG0849	cell division
BKP58_03815	COG3856	small basic protein
BKP58_03820	COG3879	Bacterial protein of unknown function (DUF881)
BKP58_03825	COG3879	Bacterial protein of unknown function (DUF881)
BKP58_03830	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKP58_03835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BKP58_03840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKP58_03845	COG0772	Belongs to the SEDS family
BKP58_03850	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKP58_03855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP58_03865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKP58_03875	COG0768	penicillin binding
BKP58_03890	COG4839	cell division protein FtsL
BKP58_03895	COG0275	rRNA processing
BKP58_03900	COG2001	Belongs to the MraZ family
BKP58_03905	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BKP58_03910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKP58_03915	COG0454	-acetyltransferase
BKP58_03925	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BKP58_03930	COG1399	metal-binding, possibly nucleic acid-binding protein
BKP58_03940	COG1323	Belongs to the UPF0348 family
BKP58_03945	COG3480	Lon protease (S16) C-terminal proteolytic domain
BKP58_03950	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKP58_03955	COG3314	Sporulation integral membrane protein YlbJ
BKP58_03960	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKP58_03965	COG0742	ribosomal rna small subunit methyltransferase
BKP58_03970	COG4471	UPF0298 protein
BKP58_03975	COG3679	Belongs to the UPF0342 family
BKP58_03990	COG2340	Cysteine-rich secretory protein family
BKP58_03995	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BKP58_04005	COG3336	cytochrome c oxidase
BKP58_04010	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BKP58_04015	COG1845	cytochrome c oxidase, subunit III
BKP58_04020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKP58_04025	COG2010	Cytochrome c
BKP58_04025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKP58_04030	COG0109	protoheme IX farnesyltransferase activity
BKP58_04035	COG1612	heme a metabolic process
BKP58_04040	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BKP58_04045	COG0772	Belongs to the SEDS family
BKP58_04050	COG4838	Belongs to the UPF0358 family
BKP58_04055	COG2066	Belongs to the glutaminase family
BKP58_04060	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKP58_04065	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BKP58_04075	COG4896	Protein conserved in bacteria
BKP58_04125	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKP58_04140	COG0483	inositol monophosphate 1-phosphatase activity
BKP58_04150	COG4493	Belongs to the UPF0637 family
BKP58_04155	COG4476	Belongs to the UPF0223 family
BKP58_04160	COG1982	Orn Lys Arg decarboxylase major
BKP58_04165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP58_04170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKP58_04175	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKP58_04180	COG0022	dehydrogenase e1 component
BKP58_04185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKP58_04200	COG0242	peptide deformylase activity
BKP58_04205	COG0561	phosphatase activity
BKP58_04215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BKP58_04220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKP58_04225	COG0569	domain protein
BKP58_04230	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BKP58_04230	COG2105	PFAM AIG2 family protein
BKP58_04235	COG3852	Histidine kinase
BKP58_04240	COG2002	toxin-antitoxin pair type II binding
BKP58_04245	COG1077	Cell shape determining protein MreB Mrl
BKP58_04255	COG2309	aminopeptidase activity
BKP58_04260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKP58_04265	COG0488	(ABC) transporter
BKP58_04275	COG0681	Belongs to the peptidase S26 family
BKP58_04280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP58_04280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP58_04280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP58_04285	COG1105	Belongs to the carbohydrate kinase PfkB family
BKP58_04290	COG1349	DNA-binding transcription factor activity
BKP58_04295	COG0577	efflux transmembrane transporter activity
BKP58_04300	COG1136	(ABC) transporter
BKP58_04305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKP58_04315	COG1132	(ABC) transporter
BKP58_04325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BKP58_04330	COG0314	molybdopterin synthase activity
BKP58_04335	COG1763	Mo-molybdopterin cofactor biosynthetic process
BKP58_04340	COG0303	'Molybdopterin
BKP58_04345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKP58_04350	COG0746	molybdenum cofactor guanylyltransferase activity
BKP58_04365	COG2801	Transposase and inactivated derivatives
BKP58_04375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP58_04380	COG0450	alkyl hydroperoxide reductase
BKP58_04385	COG0668	transmembrane transport
BKP58_04395	COG1473	amidohydrolase
BKP58_04400	COG2171	N-acyltransferase activity
BKP58_04405	COG0716	FMN binding
BKP58_04415	COG0716	FMN binding
BKP58_04420	COG0583	DNA-binding transcription factor activity
BKP58_04425	COG0517	IMP dehydrogenase activity
BKP58_04435	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BKP58_04440	COG4703	Protein of unknown function (DUF1797)
BKP58_04450	COG2200	EAL domain
BKP58_04455	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_04460	COG1408	metallophosphoesterase
BKP58_04465	COG1376	ErfK ybiS ycfS ynhG family protein
BKP58_04470	COG2814	Major facilitator Superfamily
BKP58_04480	COG0784	Response regulator, receiver
BKP58_04480	COG0835	chemotaxis
BKP58_04490	COG0436	Aminotransferase
BKP58_04495	COG4191	Histidine kinase
BKP58_04500	COG0768	penicillin binding
BKP58_04505	COG2340	Cysteine-rich secretory protein family
BKP58_04510	COG3328	transposase activity
BKP58_04515	COG2084	Dehydrogenase
BKP58_04520	COG0840	transmembrane signaling receptor activity
BKP58_04525	COG0456	acetyltransferase
BKP58_04530	COG1533	DNA photolyase activity
BKP58_04540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKP58_04545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP58_04550	COG2190	(PTS) system
BKP58_04550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP58_04550	COG1263	PTS System
BKP58_04555	COG3711	transcriptional antiterminator
BKP58_04560	COG1609	Transcriptional regulator
BKP58_04570	COG0006	proline dipeptidase activity
BKP58_04580	COG2217	Heavy metal translocating P-type atpase
BKP58_04585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP58_04590	COG2244	polysaccharide biosynthetic process
BKP58_04595	COG3773	Cell wall hydrolase
BKP58_04610	COG4873	Protein conserved in bacteria
BKP58_04620	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BKP58_04625	COG0602	queuosine metabolic process
BKP58_04630	COG0720	synthase
BKP58_04635	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BKP58_04640	COG3949	Membrane
BKP58_04645	COG0542	response to heat
BKP58_04650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKP58_04655	COG1360	Flagellar Motor Protein
BKP58_04660	COG1846	Transcriptional regulator
BKP58_04665	COG3852	Histidine kinase
BKP58_04680	COG3339	Conserved Protein
BKP58_04685	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BKP58_04690	COG0235	Class ii aldolase
BKP58_04695	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BKP58_04700	COG1850	ribulose-bisphosphate carboxylase activity
BKP58_04705	COG0436	Aminotransferase
BKP58_04710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKP58_04715	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BKP58_04720	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BKP58_04730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKP58_04735	COG5002	protein histidine kinase activity
BKP58_04740	COG3594	Acyltransferase
BKP58_04765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKP58_04770	COG0501	Belongs to the peptidase M48B family
BKP58_04790	COG1191	sigma factor activity
BKP58_04795	COG0861	Integral membrane protein TerC family
BKP58_04800	COG0586	Pfam SNARE associated Golgi protein
BKP58_04805	COG3300	MHYT domain
BKP58_04805	COG5001	Diguanylate cyclase
BKP58_04810	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKP58_04815	COG1793	dna ligase
BKP58_04815	COG3285	dna ligase
BKP58_04820	COG0463	Glycosyl transferase, family 2
BKP58_04830	COG1408	metallophosphoesterase
BKP58_04835	COG0726	polysaccharide deacetylase
BKP58_04840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKP58_04845	COG1846	Transcriptional regulator
BKP58_04860	COG0789	Transcriptional regulator
BKP58_04865	COG2239	Acts as a magnesium transporter
BKP58_04885	COG3212	peptidase
BKP58_04890	COG3212	peptidase
BKP58_04895	COG3850	Histidine kinase
BKP58_04895	COG5002	protein histidine kinase activity
BKP58_04900	COG0745	RESPONSE REGULATOR receiver
BKP58_04910	COG4721	ABC-type cobalt transport system, permease component
BKP58_04915	COG1122	ATPase activity
BKP58_04920	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BKP58_04925	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP58_04930	COG1404	Belongs to the peptidase S8 family
BKP58_04935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKP58_04940	COG0590	tRNA wobble adenosine to inosine editing
BKP58_04950	COG1764	response to oxidative stress
BKP58_04955	COG1846	Transcriptional regulator
BKP58_04960	COG1764	response to oxidative stress
BKP58_04965	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKP58_04970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BKP58_04975	COG0788	formyltetrahydrofolate deformylase activity
BKP58_04980	COG2076	Multidrug Resistance protein
BKP58_04985	COG2076	Multidrug Resistance protein
BKP58_04990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP58_04995	COG2318	DinB family
BKP58_05000	COG2323	membrane
BKP58_05010	COG1017	nitric oxide dioxygenase activity
BKP58_05010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKP58_05015	COG1607	acyl-coa hydrolase
BKP58_05025	COG2706	6-phosphogluconolactonase activity
BKP58_05030	COG4608	Belongs to the ABC transporter superfamily
BKP58_05035	COG0791	NLP P60 protein
BKP58_05040	COG4948	Mandelate Racemase Muconate Lactonizing
BKP58_05045	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKP58_05050	COG4166	transmembrane transport
BKP58_05055	COG0444	Belongs to the ABC transporter superfamily
BKP58_05060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP58_05065	COG0601	transmembrane transport
BKP58_05070	COG2362	D-Aminopeptidase
BKP58_05075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKP58_05080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP58_05090	COG0463	Glycosyl transferase, family 2
BKP58_05095	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKP58_05100	COG0346	lactoylglutathione lyase activity
BKP58_05105	COG0531	amino acid
BKP58_05110	COG1392	Phosphate transport regulator
BKP58_05115	COG0306	phosphate transporter
BKP58_05130	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKP58_05130	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_05170	COG3778	Protein conserved in bacteria
BKP58_05175	COG3299	homolog of phage Mu protein gp47
BKP58_05180	COG3628	GPW Gp25 family protein
BKP58_05190	COG4193	domain, Protein
BKP58_05195	COG1652	LysM domain
BKP58_05200	COG3953	SLT domain
BKP58_05200	COG5412	phage tail tape measure protein
BKP58_05200	COG3953	SLT domain
BKP58_05200	COG5412	phage tail tape measure protein
BKP58_05200	COG3953	SLT domain
BKP58_05200	COG5412	phage tail tape measure protein
BKP58_05250	COG4653	Phage capsid family
BKP58_05255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BKP58_05260	COG5518	Phage portal protein
BKP58_05265	COG1783	phage Terminase large subunit
BKP58_05270	COG3728	DNA packaging
BKP58_05270	COG5484	DNA packaging
BKP58_05275	COG1595	DNA-templated transcription, initiation
BKP58_05300	COG1484	DNA-dependent DNA replication
BKP58_05305	COG1522	sequence-specific DNA binding
BKP58_05315	COG1396	sequence-specific DNA binding
BKP58_05320	COG2856	Zn peptidase
BKP58_05325	COG3546	catalase activity
BKP58_05330	COG4195	phage-related replication protein
BKP58_05340	COG1388	LysM domain
BKP58_05340	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKP58_05340	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_05355	COG0457	Tetratricopeptide repeat
BKP58_05360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKP58_05370	COG2801	Transposase and inactivated derivatives
BKP58_05380	COG2318	DinB family
BKP58_05385	COG0730	response to heat
BKP58_05390	COG2721	sulfolactate sulfo-lyase activity
BKP58_05395	COG0246	Mannitol dehydrogenase
BKP58_05400	COG1609	Transcriptional regulator
BKP58_05405	COG2271	Major facilitator Superfamily
BKP58_05410	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_05415	COG1312	Catalyzes the dehydration of D-mannonate
BKP58_05420	COG1063	alcohol dehydrogenase
BKP58_05425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BKP58_05430	COG2211	Major facilitator Superfamily
BKP58_05435	COG1904	glucuronate isomerase
BKP58_05440	COG1252	NADH dehydrogenase
BKP58_05455	COG0697	spore germination
BKP58_05460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKP58_05465	COG0390	transport system, permease component
BKP58_05470	COG1587	Uroporphyrinogen-III synthase
BKP58_05480	COG1819	glycosyl
BKP58_05485	COG2124	cytochrome p450
BKP58_05495	COG1051	belongs to the nudix hydrolase family
BKP58_05505	COG2427	Protein of unknown function (DUF1641)
BKP58_05520	COG2205	protein histidine kinase activity
BKP58_05525	COG5504	Zn-dependent protease
BKP58_05545	COG0726	polysaccharide deacetylase
BKP58_05555	COG0109	protoheme IX farnesyltransferase activity
BKP58_05570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKP58_05580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP58_05595	COG1482	cell wall glycoprotein biosynthetic process
BKP58_05600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP58_05600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP58_05600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP58_05605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP58_05605	COG3711	transcriptional antiterminator
BKP58_05615	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BKP58_05670	COG3328	transposase activity
BKP58_05680	COG5444	nuclease activity
BKP58_05685	COG0457	Tetratricopeptide repeat
BKP58_05755	COG1396	sequence-specific DNA binding
BKP58_05785	COG5505	Protein of unknown function (DUF819)
BKP58_05790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP58_05795	COG0626	cystathionine gamma-synthase activity
BKP58_05800	COG0626	cystathionine gamma-synthase activity
BKP58_05805	COG2382	esterase
BKP58_05810	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BKP58_05815	COG2153	protein acetylation
BKP58_05825	COG0210	DNA helicase
BKP58_05885	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKP58_05890	COG0351	phosphomethylpyrimidine kinase
BKP58_05895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKP58_05900	COG2022	thiamine diphosphate biosynthetic process
BKP58_05905	COG2104	thiamine diphosphate biosynthetic process
BKP58_05910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP58_05915	COG0352	thiamine-phosphate diphosphorylase activity
BKP58_05920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BKP58_05925	COG0569	domain protein
BKP58_05925	COG0475	glutathione-regulated potassium exporter activity
BKP58_05930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKP58_05935	COG0564	pseudouridine synthase activity
BKP58_05940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKP58_05945	COG2357	RelA SpoT domain protein
BKP58_05955	COG4116	CYTH
BKP58_05960	COG0741	lytic transglycosylase activity
BKP58_05965	COG2346	COG2346, Truncated hemoglobins
BKP58_05985	COG1164	Oligoendopeptidase f
BKP58_05990	COG4469	Competence protein
BKP58_05995	COG4862	establishment of competence for transformation
BKP58_06000	COG0861	Integral membrane protein TerC family
BKP58_06005	COG1393	Belongs to the ArsC family
BKP58_06010	COG0456	acetyltransferase
BKP58_06015	COG2814	Major facilitator Superfamily
BKP58_06020	COG4608	Belongs to the ABC transporter superfamily
BKP58_06025	COG0444	Belongs to the ABC transporter superfamily
BKP58_06030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP58_06035	COG0601	transmembrane transport
BKP58_06040	COG4166	transmembrane transport
BKP58_06045	COG0180	Tryptophanyl-tRNA synthetase
BKP58_06055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP58_06060	COG0601	transmembrane transport
BKP58_06070	COG4608	Belongs to the ABC transporter superfamily
BKP58_06075	COG0444	Belongs to the ABC transporter superfamily
BKP58_06080	COG5504	Zn-dependent protease
BKP58_06085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKP58_06090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKP58_06105	COG1744	ABC transporter substrate-binding protein PnrA-like
BKP58_06115	COG2267	carboxylic ester hydrolase activity
BKP58_06135	COG2801	Transposase and inactivated derivatives
BKP58_06140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKP58_06145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKP58_06150	COG0505	Belongs to the CarA family
BKP58_06155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKP58_06170	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BKP58_06190	COG2151	metal-sulfur cluster biosynthetic enzyme
BKP58_06195	COG1073	alpha beta
BKP58_06200	COG0561	phosphatase activity
BKP58_06220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP58_06225	COG1307	EDD domain protein, DegV family
BKP58_06235	COG2996	Protein conserved in bacteria
BKP58_06240	COG1666	GTP binding
BKP58_06245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BKP58_06245	COG0646	methionine synthase
BKP58_06250	COG2153	protein acetylation
BKP58_06260	COG2267	carboxylic ester hydrolase activity
BKP58_06265	COG1357	PFAM Pentapeptide repeats (8 copies)
BKP58_06270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKP58_06275	COG1279	arginine transmembrane transporter activity
BKP58_06280	COG2318	DinB family
BKP58_06285	COG0673	inositol 2-dehydrogenase activity
BKP58_06290	COG1609	Transcriptional regulator
BKP58_06295	COG2207	Transcriptional regulator
BKP58_06295	COG1917	Cupin 2, conserved barrel domain protein
BKP58_06300	COG0534	Mate efflux family protein
BKP58_06305	COG1562	ergosterol biosynthetic process
BKP58_06310	COG0367	asparagine synthase
BKP58_06320	COG1404	Belongs to the peptidase S8 family
BKP58_06330	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKP58_06335	COG5337	Spore coat protein CotH
BKP58_06380	COG1403	HNH endonuclease
BKP58_06385	COG0419	ATPase involved in DNA repair
BKP58_06390	COG0420	3'-5' exonuclease activity
BKP58_06395	COG1074	ATP-dependent DNA helicase activity
BKP58_06400	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BKP58_06405	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BKP58_06420	COG4533	DNA binding
BKP58_06425	COG2814	Major facilitator Superfamily
BKP58_06425	COG0477	Major facilitator Superfamily
BKP58_06430	COG3180	Ammonia monooxygenase
BKP58_06435	COG1609	Transcriptional regulator
BKP58_06440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKP58_06445	COG0561	phosphatase activity
BKP58_06450	COG0673	inositol 2-dehydrogenase activity
BKP58_06455	COG0738	Major facilitator superfamily
BKP58_06470	COG1846	Transcriptional regulator
BKP58_06475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKP58_06480	COG0681	Belongs to the peptidase S26 family
BKP58_06485	COG0398	Pfam SNARE associated Golgi protein
BKP58_06500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP58_06510	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_06515	COG4903	ComK protein
BKP58_06525	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_06535	COG0840	transmembrane signaling receptor activity
BKP58_06540	COG1268	BioY protein
BKP58_06545	COG0318	PFAM AMP-dependent synthetase and ligase
BKP58_06550	COG0183	Belongs to the thiolase family
BKP58_06555	COG0406	alpha-ribazole phosphatase activity
BKP58_06560	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BKP58_06565	COG0604	alcohol dehydrogenase
BKP58_06570	COG0456	acetyltransferase
BKP58_06580	COG0501	Belongs to the peptidase M48B family
BKP58_06590	COG0318	PFAM AMP-dependent synthetase and ligase
BKP58_06595	COG0702	epimerase
BKP58_06600	COG0095	Lipoate-protein ligase
BKP58_06605	COG1234	tRNA 3'-trailer cleavage
BKP58_06615	COG1301	dicarboxylic acid transport
BKP58_06620	COG4405	Protein conserved in bacteria
BKP58_06625	COG1363	Peptidase, m42
BKP58_06635	COG4377	Putative membrane peptidase family (DUF2324)
BKP58_06640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKP58_06645	COG1511	domain protein
BKP58_06650	COG1309	transcriptional regulator
BKP58_06665	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKP58_06670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP58_06675	COG2329	Antibiotic biosynthesis monooxygenase
BKP58_06685	COG3069	C4-dicarboxylate transmembrane transporter activity
BKP58_06690	COG1473	amidohydrolase
BKP58_06700	COG4473	ABC transporter
BKP58_06705	COG1131	(ABC) transporter
BKP58_06710	COG0537	adenosine 5'-monophosphoramidase activity
BKP58_06715	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BKP58_06730	COG4980	gas vesicle protein
BKP58_06735	COG1846	Transcriptional regulator
BKP58_06755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKP58_06765	COG3481	metal-dependent phosphohydrolase, HD sub domain
BKP58_06770	COG4717	serine-type aminopeptidase activity
BKP58_06775	COG0420	3'-5' exonuclease activity
BKP58_06780	COG1668	transmembrane transport
BKP58_06785	COG4152	abc transporter atp-binding protein
BKP58_06795	COG1024	Enoyl-CoA hydratase
BKP58_06805	COG0490	domain, Protein
BKP58_06810	COG0475	glutathione-regulated potassium exporter activity
BKP58_06815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKP58_06820	COG0561	phosphatase activity
BKP58_06830	COG3679	Belongs to the UPF0342 family
BKP58_06835	COG4399	Belongs to the UPF0754 family
BKP58_06840	COG0189	ligase activity
BKP58_06845	COG0189	ligase activity
BKP58_06865	COG0702	epimerase
BKP58_06870	COG1132	(ABC) transporter
BKP58_06875	COG1132	(ABC) transporter
BKP58_06885	COG0589	response to stress
BKP58_06890	COG1757	Na H antiporter
BKP58_06895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKP58_06900	COG0726	polysaccharide deacetylase
BKP58_06905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKP58_06910	COG0668	transmembrane transport
BKP58_06920	COG0584	glycerophosphoryl diester phosphodiesterase
BKP58_06925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKP58_06930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKP58_06935	COG1253	flavin adenine dinucleotide binding
BKP58_06945	COG0789	Transcriptional regulator
BKP58_06950	COG1253	flavin adenine dinucleotide binding
BKP58_06955	COG0204	Acyl-transferase
BKP58_06960	COG0667	Aldo Keto reductase
BKP58_06965	COG1595	DNA-templated transcription, initiation
BKP58_06980	COG0456	acetyltransferase
BKP58_06985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKP58_06990	COG0733	neurotransmitter:sodium symporter activity
BKP58_06995	COG0531	amino acid
BKP58_07000	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_07005	COG0372	Belongs to the citrate synthase family
BKP58_07010	COG0583	DNA-binding transcription factor activity
BKP58_07015	COG1388	LysM domain
BKP58_07015	COG0791	NLP P60 protein
BKP58_07020	COG1785	Belongs to the alkaline phosphatase family
BKP58_07025	COG2719	SpoVR family
BKP58_07030	COG0668	transmembrane transport
BKP58_07035	COG1959	2 iron, 2 sulfur cluster binding
BKP58_07040	COG1388	LysM domain
BKP58_07040	COG0791	NLP P60 protein
BKP58_07055	COG0431	NADPH-dependent FMN reductase
BKP58_07060	COG2197	response regulator
BKP58_07065	COG2203	Gaf domain
BKP58_07065	COG4585	Histidine kinase
BKP58_07070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKP58_07075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKP58_07080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKP58_07085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKP58_07090	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BKP58_07095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKP58_07100	COG3153	acetyltransferase
BKP58_07100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKP58_07105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKP58_07110	COG0517	IMP dehydrogenase activity
BKP58_07120	COG0564	pseudouridine synthase activity
BKP58_07125	COG3764	Sortase (surface protein transpeptidase)
BKP58_07130	COG4085	toxin activity
BKP58_07130	COG0737	Belongs to the 5'-nucleotidase family
BKP58_07130	COG1525	nuclease
BKP58_07135	COG5577	PFAM Coat F domain
BKP58_07155	COG0457	Tetratricopeptide repeat
BKP58_07175	COG0791	NLP P60 protein
BKP58_07175	COG0741	lytic transglycosylase activity
BKP58_07180	COG5644	endopeptidase inhibitor activity
BKP58_07230	COG0582	viral genome integration into host DNA
BKP58_07255	COG5444	nuclease activity
BKP58_07260	COG1823	symporter activity
BKP58_07265	COG3706	GGDEF domain
BKP58_07270	COG1464	Belongs to the NlpA lipoprotein family
BKP58_07275	COG1278	Cold shock
BKP58_07280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKP58_07285	COG1131	(ABC) transporter
BKP58_07290	COG1131	(ABC) transporter
BKP58_07295	COG1725	Transcriptional regulator
BKP58_07310	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKP58_07315	COG2814	Major facilitator Superfamily
BKP58_07320	COG1566	PFAM secretion protein HlyD family protein
BKP58_07325	COG1846	Transcriptional regulator
BKP58_07335	COG2718	Belongs to the UPF0229 family
BKP58_07340	COG2766	serine protein kinase
BKP58_07345	COG1664	Polymer-forming cytoskeletal
BKP58_07350	COG1664	Polymer-forming cytoskeletal
BKP58_07355	COG0789	Transcriptional regulator
BKP58_07360	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BKP58_07370	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BKP58_07375	COG3382	B3 4 domain protein
BKP58_07385	COG1476	TRANSCRIPTIONal
BKP58_07395	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKP58_07405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP58_07410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKP58_07415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKP58_07420	COG1116	anion transmembrane transporter activity
BKP58_07425	COG0753	catalase activity
BKP58_07440	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BKP58_07445	COG3340	Belongs to the peptidase S51 family
BKP58_07450	COG5577	PFAM Coat F domain
BKP58_07460	COG4326	sporulation control protein
BKP58_07575	COG0735	belongs to the Fur family
BKP58_07580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BKP58_07585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKP58_07590	COG4129	membrane
BKP58_07595	COG1132	(ABC) transporter
BKP58_07600	COG3557	Belongs to the UPF0374 family
BKP58_07615	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_07625	COG1194	a g-specific adenine glycosylase
BKP58_07630	COG1988	membrane-bound metal-dependent
BKP58_07635	COG4485	Bacterial membrane protein, YfhO
BKP58_07640	COG0463	Glycosyl transferase, family 2
BKP58_07645	COG0596	Alpha beta hydrolase
BKP58_07650	COG5658	integral membrane protein
BKP58_07655	COG3103	Sh3 type 3 domain protein
BKP58_07670	COG2814	Major facilitator Superfamily
BKP58_07685	COG2137	regulation of response to DNA damage stimulus
BKP58_07690	COG1090	epimerase
BKP58_07705	COG0778	Nitroreductase
BKP58_07710	COG0384	phenazine biosynthesis protein PhzF
BKP58_07715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP58_07720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP58_07725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP58_07730	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BKP58_07730	COG0392	lysyltransferase activity
BKP58_07735	COG1846	Transcriptional regulator
BKP58_07745	COG2318	DinB family
BKP58_07750	COG2814	Major facilitator Superfamily
BKP58_07755	COG1309	transcriptional regulator
BKP58_07760	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BKP58_07765	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BKP58_07770	COG1695	Transcriptional regulator
BKP58_07775	COG0842	Transport permease protein
BKP58_07780	COG0842	Transport permease protein
BKP58_07780	COG1511	domain protein
BKP58_07790	COG2197	response regulator
BKP58_07795	COG4585	Histidine kinase
BKP58_07805	COG1082	Xylose isomerase domain protein TIM barrel
BKP58_07810	COG2814	Major facilitator Superfamily
BKP58_07815	COG1917	Cupin 2, conserved barrel domain protein
BKP58_07815	COG4977	sequence-specific DNA binding
BKP58_07820	COG2514	catechol 2,3-dioxygenase activity
BKP58_07825	COG2259	Doxx family
BKP58_07830	COG1132	(ABC) transporter
BKP58_07835	COG1132	(ABC) transporter
BKP58_07840	COG5434	Belongs to the glycosyl hydrolase 28 family
BKP58_07845	COG1263	PTS System
BKP58_07845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP58_07850	COG1737	Transcriptional regulator
BKP58_07855	COG1486	melibiose metabolic process
BKP58_07860	COG4842	Belongs to the WXG100 family
BKP58_07885	COG1742	UPF0060 membrane protein
BKP58_07895	COG3284	Transcriptional regulator
BKP58_07900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKP58_07905	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKP58_07910	COG0022	dehydrogenase e1 component
BKP58_07915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKP58_07925	COG4637	Psort location Cytoplasmic, score
BKP58_07930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKP58_07940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKP58_07945	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BKP58_07950	COG0598	Magnesium transport protein CorA
BKP58_07955	COG2084	Dehydrogenase
BKP58_07960	COG0726	polysaccharide deacetylase
BKP58_07970	COG0535	radical SAM domain protein
BKP58_07975	COG0668	transmembrane transport
BKP58_07985	COG0387	Pfam Sodium calcium exchanger
BKP58_07995	COG0477	Major facilitator Superfamily
BKP58_08005	COG1295	ribonuclease BN
BKP58_08010	COG4980	gas vesicle protein
BKP58_08015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKP58_08020	COG4840	Belongs to the UPF0435 family
BKP58_08025	COG2814	Major facilitator Superfamily
BKP58_08030	COG2801	Transposase and inactivated derivatives
BKP58_08040	COG0693	protein deglycase activity
BKP58_08045	COG0737	Belongs to the 5'-nucleotidase family
BKP58_08050	COG0778	Nitroreductase
BKP58_08055	COG2188	Transcriptional regulator
BKP58_08060	COG0366	Alpha amylase catalytic
BKP58_08065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP58_08065	COG1263	PTS System
BKP58_08070	COG0697	spore germination
BKP58_08075	COG0531	amino acid
BKP58_08080	COG1115	amino acid carrier protein
BKP58_08090	COG1368	sulfuric ester hydrolase activity
BKP58_08095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP58_08095	COG1263	PTS System
BKP58_08100	COG0024	Methionine aminopeptidase
BKP58_08120	COG2258	MOSC domain
BKP58_08125	COG1254	Belongs to the acylphosphatase family
BKP58_08130	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BKP58_08135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP58_08140	COG2851	Citrate transporter
BKP58_08150	COG3181	Tripartite tricarboxylate transporter family receptor
BKP58_08155	COG4565	transcriptional regulatory protein
BKP58_08160	COG3290	protein histidine kinase activity
BKP58_08165	COG0471	metal ion transport
BKP58_08170	COG3866	Pectate lyase
BKP58_08180	COG0513	Belongs to the DEAD box helicase family
BKP58_08185	COG0488	(ABC) transporter
BKP58_08190	COG2801	Transposase and inactivated derivatives
BKP58_08205	COG2814	Major facilitator Superfamily
BKP58_08210	COG0789	Transcriptional regulator
BKP58_08220	COG0488	(ABC) transporter
BKP58_08225	COG0840	transmembrane signaling receptor activity
BKP58_08230	COG1012	belongs to the aldehyde dehydrogenase family
BKP58_08235	COG0531	amino acid
BKP58_08240	COG1011	Hydrolase
BKP58_08245	COG2223	nitrite transmembrane transporter activity
BKP58_08250	COG1442	glycosyl transferase family 8
BKP58_08255	COG1216	Glycosyl transferase, family 2
BKP58_08260	COG1442	glycosyl transferase family 8
BKP58_08265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKP58_08270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKP58_08275	COG1368	sulfuric ester hydrolase activity
BKP58_08280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKP58_08280	COG2124	cytochrome p450
BKP58_08290	COG3328	transposase activity
BKP58_08300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKP58_08305	COG0670	Belongs to the BI1 family
BKP58_08310	COG5583	Uncharacterized small protein (DUF2292)
BKP58_08325	COG0346	lactoylglutathione lyase activity
BKP58_08330	COG2329	Antibiotic biosynthesis monooxygenase
BKP58_08335	COG2323	membrane
BKP58_08340	COG1486	melibiose metabolic process
BKP58_08345	COG0395	ABC-type sugar transport system, permease component
BKP58_08350	COG4209	transmembrane transport
BKP58_08355	COG1653	transport
BKP58_08370	COG2755	lipolytic protein G-D-S-L family
BKP58_08375	COG3401	FG-GAP repeat protein
BKP58_08380	COG3401	FG-GAP repeat protein
BKP58_08385	COG5578	integral membrane protein
BKP58_08395	COG2755	lipolytic protein G-D-S-L family
BKP58_08400	COG2207	Transcriptional regulator
BKP58_08405	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BKP58_08410	COG0395	ABC-type sugar transport system, permease component
BKP58_08415	COG1175	transmembrane transport
BKP58_08420	COG1653	transport
BKP58_08430	COG2972	Histidine kinase
BKP58_08435	COG5578	integral membrane protein
BKP58_08445	COG0454	-acetyltransferase
BKP58_08450	COG3546	catalase activity
BKP58_08465	COG1309	transcriptional regulator
BKP58_08475	COG0217	transcriptional regulatory protein
BKP58_08485	COG0457	Tetratricopeptide repeat
BKP58_08495	COG5444	nuclease activity
BKP58_08520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKP58_08525	COG1597	lipid kinase activity
BKP58_08530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKP58_08535	COG1309	transcriptional regulator
BKP58_08540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKP58_08545	COG0154	amidase activity
BKP58_08550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKP58_08555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP58_08560	COG1285	pathogenesis
BKP58_08565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKP58_08570	COG2801	Transposase and inactivated derivatives
BKP58_08580	COG4851	CamS sex pheromone cAM373 precursor
BKP58_08585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKP58_08590	COG0210	DNA helicase
BKP58_08595	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BKP58_08605	COG0069	glutamate synthase activity
BKP58_08610	COG4496	protein, YerC YecD
BKP58_08615	COG1470	cell adhesion involved in biofilm formation
BKP58_08620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKP58_08630	COG0531	amino acid
BKP58_08635	COG1522	sequence-specific DNA binding
BKP58_08640	COG0151	Belongs to the GarS family
BKP58_08645	COG0138	bifunctional purine biosynthesis protein purh
BKP58_08650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BKP58_08655	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKP58_08660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BKP58_08665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKP58_08670	COG0047	phosphoribosylformylglycinamidine synthase activity
BKP58_08675	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKP58_08680	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKP58_08685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKP58_08690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BKP58_08695	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKP58_08705	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BKP58_08715	COG3064	Membrane
BKP58_08720	COG2252	PERMEase
BKP58_08730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKP58_08730	COG0519	Catalyzes the synthesis of GMP from XMP
BKP58_08735	COG1305	Transglutaminase-like
BKP58_08740	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BKP58_08745	COG0714	Associated with various cellular activities
BKP58_08750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKP58_08760	COG1113	amino acid transport
BKP58_08765	COG2132	Multicopper oxidase
BKP58_08775	COG2267	carboxylic ester hydrolase activity
BKP58_08795	COG2801	Transposase and inactivated derivatives
BKP58_08800	COG0823	Involved in the tonB-independent uptake of proteins
BKP58_08805	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKP58_08810	COG1063	alcohol dehydrogenase
BKP58_08815	COG2814	Major facilitator Superfamily
BKP58_08825	COG4260	virion core protein, lumpy skin disease virus
BKP58_08830	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BKP58_08835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKP58_08845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP58_08850	COG2211	Major facilitator Superfamily
BKP58_08855	COG1063	alcohol dehydrogenase
BKP58_08860	COG0457	Tetratricopeptide repeat
BKP58_08875	COG0459	protein refolding
BKP58_08880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKP58_08885	COG1266	CAAX protease self-immunity
BKP58_08895	COG0805	protein transport
BKP58_08900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKP58_08905	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BKP58_08910	COG0315	cyclic pyranopterin monophosphate synthase activity
BKP58_08915	COG0488	(ABC) transporter
BKP58_08920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKP58_08925	COG0456	acetyltransferase
BKP58_08930	COG1214	PFAM Peptidase M22, glycoprotease
BKP58_08935	COG0802	atpase or kinase
BKP58_08940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BKP58_08985	COG4124	Belongs to the glycosyl hydrolase 26 family
BKP58_08995	COG1940	carbohydrate kinase activity
BKP58_09000	COG2188	Transcriptional regulator
BKP58_09005	COG2723	6-phospho-beta-galactosidase activity
BKP58_09020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP58_09025	COG2814	Major facilitator Superfamily
BKP58_09030	COG1388	LysM domain
BKP58_09035	COG1078	dGTPase activity
BKP58_09040	COG0454	-acetyltransferase
BKP58_09050	COG5646	InterPro IPR014922
BKP58_09055	COG1785	Belongs to the alkaline phosphatase family
BKP58_09065	COG1819	glycosyl
BKP58_09070	COG3858	chitin binding
BKP58_09070	COG1388	LysM domain
BKP58_09075	COG1802	Transcriptional regulator
BKP58_09080	COG0730	response to heat
BKP58_09085	COG2814	Major facilitator Superfamily
BKP58_09090	COG1846	Transcriptional regulator
BKP58_09095	COG0778	Nitroreductase
BKP58_09100	COG1033	growth of symbiont in host cell
BKP58_09100	COG2409	Drug exporters of the RND superfamily
BKP58_09105	COG1846	Transcriptional regulator
BKP58_09110	COG2318	DinB family
BKP58_09115	COG1113	amino acid transport
BKP58_09125	COG0456	acetyltransferase
BKP58_09135	COG1309	transcriptional regulator
BKP58_09150	COG0071	Belongs to the small heat shock protein (HSP20) family
BKP58_09155	COG2323	membrane
BKP58_09185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP58_09190	COG2259	Doxx family
BKP58_09195	COG0346	lactoylglutathione lyase activity
BKP58_09200	COG0778	Nitroreductase
BKP58_09205	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKP58_09210	COG0789	Transcriptional regulator
BKP58_09210	COG4978	Transcriptional regulator
BKP58_09215	COG1811	Na channel or pump
BKP58_09220	COG0596	Alpha beta hydrolase
BKP58_09225	COG2409	Drug exporters of the RND superfamily
BKP58_09230	COG2197	response regulator
BKP58_09235	COG4585	Histidine kinase
BKP58_09245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKP58_09250	COG0640	Transcriptional regulator
BKP58_09255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKP58_09260	COG0076	glutamate decarboxylase activity
BKP58_09265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKP58_09270	COG0697	spore germination
BKP58_09275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP58_09285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKP58_09290	COG0640	Transcriptional regulator
BKP58_09295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP58_09305	COG3545	Serine hydrolase
BKP58_09310	COG2030	dehydratase
BKP58_09315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKP58_09320	COG0697	spore germination
BKP58_09325	COG1309	transcriptional regulator
BKP58_09330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP58_09345	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BKP58_09360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKP58_09365	COG2207	Transcriptional regulator
BKP58_09365	COG3708	Transcriptional regulator
BKP58_09375	COG1917	Cupin 2, conserved barrel domain protein
BKP58_09375	COG2207	Transcriptional regulator
BKP58_09380	COG0697	spore germination
BKP58_09385	COG1329	Transcriptional regulator
BKP58_09390	COG1278	Cold shock
BKP58_09395	COG0693	protein deglycase activity
BKP58_09420	COG1476	TRANSCRIPTIONal
BKP58_09425	COG5444	nuclease activity
BKP58_09440	COG0583	DNA-binding transcription factor activity
BKP58_09470	COG0457	Tetratricopeptide repeat
BKP58_09485	COG0791	NLP P60 protein
BKP58_09485	COG0741	lytic transglycosylase activity
BKP58_09495	COG3328	transposase activity
BKP58_09500	COG5644	endopeptidase inhibitor activity
BKP58_09510	COG0433	COG0433 Predicted ATPase
BKP58_09550	COG2946	Replication initiation factor
BKP58_09555	COG1674	ftsk spoiiie
BKP58_09580	COG1396	sequence-specific DNA binding
BKP58_09585	COG2856	Zn peptidase
BKP58_09590	COG0582	viral genome integration into host DNA
BKP58_09630	COG3091	SprT-like family
BKP58_09640	COG2183	response to ionizing radiation
BKP58_09645	COG1846	Transcriptional regulator
BKP58_09650	COG1673	EVE domain
BKP58_09665	COG2208	phosphoserine phosphatase activity
BKP58_09670	COG1191	sigma factor activity
BKP58_09675	COG2172	sigma factor antagonist activity
BKP58_09680	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP58_09685	COG2208	phosphoserine phosphatase activity
BKP58_09690	COG2172	sigma factor antagonist activity
BKP58_09695	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP58_09700	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP58_09705	COG2337	Toxic component of a toxin-antitoxin (TA) module
BKP58_09710	COG0864	Transcriptional regulator
BKP58_09715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKP58_09720	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BKP58_09725	COG0736	holo-[acyl-carrier-protein] synthase activity
BKP58_09730	COG0705	Rhomboid family
BKP58_09735	COG3428	Bacterial PH domain
BKP58_09740	COG3402	PFAM membrane-flanked domain
BKP58_09745	COG0513	Belongs to the DEAD box helicase family
BKP58_09750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BKP58_09755	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKP58_09760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP58_09765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKP58_09780	COG1960	acyl-CoA dehydrogenase activity
BKP58_09790	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKP58_09795	COG1131	(ABC) transporter
BKP58_09805	COG0628	permease
BKP58_09810	COG1301	dicarboxylic acid transport
BKP58_09815	COG4565	transcriptional regulatory protein
BKP58_09820	COG3290	protein histidine kinase activity
BKP58_09825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKP58_09830	COG3546	catalase activity
BKP58_09835	COG2329	Antibiotic biosynthesis monooxygenase
BKP58_09840	COG0662	Cupin 2, conserved barrel domain protein
BKP58_09845	COG3729	General stress protein
BKP58_09850	COG2217	Heavy metal translocating P-type atpase
BKP58_09855	COG4876	unkown
BKP58_09860	COG2261	transglycosylase associated protein
BKP58_09865	COG1914	H( )-stimulated, divalent metal cation uptake system
BKP58_09895	COG0028	Belongs to the TPP enzyme family
BKP58_09900	COG0494	nUDIX hydrolase
BKP58_09905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKP58_09905	COG0551	DNA topoisomerase type I activity
BKP58_09910	COG1522	sequence-specific DNA binding
BKP58_09915	COG2814	Major facilitator Superfamily
BKP58_09925	COG3871	stress protein (general stress protein 26)
BKP58_09930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP58_09935	COG1917	Cupin 2, conserved barrel domain protein
BKP58_09940	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_09945	COG2226	methyltransferase
BKP58_09950	COG0318	PFAM AMP-dependent synthetase and ligase
BKP58_09955	COG3711	transcriptional antiterminator
BKP58_09960	COG4989	oxidoreductase activity
BKP58_09965	COG0768	penicillin binding
BKP58_09970	COG2329	Antibiotic biosynthesis monooxygenase
BKP58_09980	COG2755	lipolytic protein G-D-S-L family
BKP58_09985	COG1414	Transcriptional regulator
BKP58_09990	COG1984	allophanate hydrolase subunit 2
BKP58_09995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKP58_10000	COG4336	lyase activity
BKP58_10005	COG1914	H( )-stimulated, divalent metal cation uptake system
BKP58_10010	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKP58_10015	COG0561	phosphatase activity
BKP58_10025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKP58_10035	COG0681	Belongs to the peptidase S26 family
BKP58_10040	COG0473	3-isopropylmalate dehydrogenase activity
BKP58_10045	COG0246	Mannitol dehydrogenase
BKP58_10050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP58_10055	COG2213	PTS system mannitol-specific
BKP58_10065	COG1349	DNA-binding transcription factor activity
BKP58_10070	COG2372	response to copper ion
BKP58_10070	COG1276	copper resistance
BKP58_10075	COG4549	nuclear export factor GLE1
BKP58_10080	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_10090	COG1012	belongs to the aldehyde dehydrogenase family
BKP58_10095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKP58_10100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKP58_10105	COG0640	Transcriptional regulator
BKP58_10110	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BKP58_10115	COG0778	Nitroreductase
BKP58_10120	COG1309	transcriptional regulator
BKP58_10125	COG2814	Major facilitator Superfamily
BKP58_10135	COG4607	ABC-type enterochelin transport system periplasmic component
BKP58_10140	COG4604	ABC transporter, ATP-binding protein
BKP58_10145	COG4605	iron ion homeostasis
BKP58_10150	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP58_10155	COG0527	aspartate kinase activity
BKP58_10170	COG0457	Tetratricopeptide repeat
BKP58_10175	COG3850	Histidine kinase
BKP58_10175	COG5002	protein histidine kinase activity
BKP58_10180	COG0745	RESPONSE REGULATOR receiver
BKP58_10185	COG0577	efflux transmembrane transporter activity
BKP58_10190	COG1136	(ABC) transporter
BKP58_10195	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BKP58_10205	COG0697	spore germination
BKP58_10215	COG5434	Belongs to the glycosyl hydrolase 28 family
BKP58_10220	COG3104	oligopeptide transport
BKP58_10225	COG0596	Alpha beta hydrolase
BKP58_10240	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BKP58_10245	COG0163	prenyltransferase activity
BKP58_10250	COG0583	DNA-binding transcription factor activity
BKP58_10255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP58_10260	COG0765	amino acid transport
BKP58_10265	COG1126	abc transporter atp-binding protein
BKP58_10270	COG2364	Membrane
BKP58_10280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKP58_10285	COG0697	spore germination
BKP58_10295	COG2814	Major facilitator Superfamily
BKP58_10300	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BKP58_10305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKP58_10310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKP58_10315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKP58_10325	COG1733	regulation of RNA biosynthetic process
BKP58_10330	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BKP58_10335	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BKP58_10345	COG3209	COG3209 Rhs family protein
BKP58_10355	COG2723	6-phospho-beta-galactosidase activity
BKP58_10370	COG1846	Transcriptional regulator
BKP58_10380	COG1714	RDD family
BKP58_10390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP58_10395	COG0765	amino acid transport
BKP58_10410	COG1376	ErfK ybiS ycfS ynhG family protein
BKP58_10420	COG2223	nitrite transmembrane transporter activity
BKP58_10425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKP58_10430	COG0243	molybdopterin cofactor binding
BKP58_10435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKP58_10440	COG2146	nitrite reductase [NAD(P)H] activity
BKP58_10445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKP58_10445	COG1587	Uroporphyrinogen-III synthase
BKP58_10450	COG0492	ferredoxin-NADP+ reductase activity
BKP58_10455	COG2267	carboxylic ester hydrolase activity
BKP58_10460	COG0701	Predicted permease
BKP58_10465	COG3689	TIGRFAM TIGR03943 family protein
BKP58_10470	COG2508	Transcriptional regulator
BKP58_10475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP58_10480	COG1012	belongs to the aldehyde dehydrogenase family
BKP58_10485	COG0506	proline dehydrogenase activity
BKP58_10490	COG3541	Predicted nucleotidyltransferase
BKP58_10495	COG3458	cephalosporin-C deacetylase activity
BKP58_10500	COG0583	DNA-binding transcription factor activity
BKP58_10505	COG2226	methyltransferase
BKP58_10520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKP58_10525	COG1660	Displays ATPase and GTPase activities
BKP58_10530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKP58_10545	COG3403	YqcI/YcgG family
BKP58_10555	COG0039	L-malate dehydrogenase activity
BKP58_10575	COG1288	antiporter activity
BKP58_10580	COG1473	amidohydrolase
BKP58_10585	COG2113	Glycine betaine
BKP58_10590	COG4176	ABC-type proline glycine betaine transport system permease component
BKP58_10595	COG0517	IMP dehydrogenase activity
BKP58_10595	COG4175	Glycine betaine
BKP58_10600	COG0640	Transcriptional regulator
BKP58_10605	COG2814	Major facilitator Superfamily
BKP58_10610	COG0477	Major facilitator Superfamily
BKP58_10615	COG2801	Transposase and inactivated derivatives
BKP58_10625	COG3853	Toxic anion resistance protein (TelA)
BKP58_10635	COG0861	Integral membrane protein TerC family
BKP58_10640	COG2310	stress, protein
BKP58_10645	COG2310	stress, protein
BKP58_10650	COG2310	stress, protein
BKP58_10660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP58_10665	COG1121	(ABC) transporter
BKP58_10670	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKP58_10675	COG0366	Alpha amylase catalytic
BKP58_10680	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_10685	COG0457	Tetratricopeptide repeat
BKP58_10690	COG0457	Tetratricopeptide repeat
BKP58_10695	COG1876	peptidase activity
BKP58_10700	COG1595	DNA-templated transcription, initiation
BKP58_10705	COG1595	DNA-templated transcription, initiation
BKP58_10715	COG0667	Aldo Keto reductase
BKP58_10720	COG1668	transmembrane transport
BKP58_10730	COG3279	Response regulator of the LytR AlgR family
BKP58_10740	COG1405	negative regulation of cell septum assembly
BKP58_10740	COG3012	SEC-C Motif Domain Protein
BKP58_10745	COG1714	RDD family
BKP58_10750	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BKP58_10755	COG0252	asparaginase activity
BKP58_10760	COG1309	transcriptional regulator
BKP58_10765	COG0477	Major facilitator Superfamily
BKP58_10770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKP58_10775	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BKP58_10780	COG0805	protein transport
BKP58_10785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKP58_10790	COG3540	Alkaline phosphatase
BKP58_10800	COG2304	oxidoreductase activity
BKP58_10805	COG3773	Cell wall hydrolase
BKP58_10825	COG1131	(ABC) transporter
BKP58_10830	COG2205	protein histidine kinase activity
BKP58_10835	COG0745	RESPONSE REGULATOR receiver
BKP58_10840	COG0697	spore germination
BKP58_10850	COG3173	Aminoglycoside phosphotransferase
BKP58_10855	COG2721	sulfolactate sulfo-lyase activity
BKP58_10860	COG2186	Transcriptional regulator
BKP58_10865	COG4948	Mandelate Racemase Muconate Lactonizing
BKP58_10870	COG2271	Major facilitator Superfamily
BKP58_10875	COG1012	belongs to the aldehyde dehydrogenase family
BKP58_10880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP58_10885	COG0784	Response regulator, receiver
BKP58_10890	COG4191	Histidine kinase
BKP58_10895	COG2066	Belongs to the glutaminase family
BKP58_10910	COG2040	homocysteine
BKP58_10915	COG0833	amino acid
BKP58_10920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKP58_10935	COG0363	glucosamine-6-phosphate deaminase activity
BKP58_10940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP58_10940	COG1263	PTS System
BKP58_10940	COG2190	(PTS) system
BKP58_10945	COG1301	dicarboxylic acid transport
BKP58_10955	COG2207	Transcriptional regulator
BKP58_10960	COG2312	Erythromycin esterase
BKP58_10970	COG0688	phosphatidylethanolamine metabolic process
BKP58_10975	COG0586	Pfam SNARE associated Golgi protein
BKP58_10980	COG1183	phosphatidylcholine synthase activity
BKP58_10985	COG0596	Alpha beta hydrolase
BKP58_10995	COG3591	Belongs to the peptidase S1B family
BKP58_11000	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BKP58_11010	COG1388	LysM domain
BKP58_11010	COG3942	CHAP domain
BKP58_11025	COG1917	Cupin 2, conserved barrel domain protein
BKP58_11025	COG2207	Transcriptional regulator
BKP58_11030	COG0697	spore germination
BKP58_11035	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_11055	COG1846	Transcriptional regulator
BKP58_11055	COG0456	acetyltransferase
BKP58_11065	COG2271	Major facilitator Superfamily
BKP58_11070	COG0584	glycerophosphoryl diester phosphodiesterase
BKP58_11075	COG0531	amino acid
BKP58_11085	COG2124	cytochrome p450
BKP58_11090	COG2602	Beta-lactamase
BKP58_11105	COG1113	amino acid transport
BKP58_11120	COG0515	serine threonine protein kinase
BKP58_11130	COG0642	Histidine kinase
BKP58_11140	COG5609	conserved protein (DUF2294)
BKP58_11150	COG0288	reversible hydration of carbon dioxide
BKP58_11155	COG3002	Belongs to the UPF0753 family
BKP58_11160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKP58_11165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKP58_11170	COG2169	Transcriptional regulator
BKP58_11180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKP58_11185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKP58_11190	COG4856	YbbR-like protein
BKP58_11195	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BKP58_11200	COG5662	AntiSigma factor
BKP58_11205	COG1595	DNA-templated transcription, initiation
BKP58_11235	COG1683	Conserved Protein
BKP58_11240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP58_11245	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BKP58_11250	COG1737	Transcriptional regulator
BKP58_11255	COG1263	PTS System
BKP58_11255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP58_11260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKP58_11265	COG1472	Belongs to the glycosyl hydrolase 3 family
BKP58_11270	COG3876	Protein conserved in bacteria
BKP58_11275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP58_11275	COG2207	Transcriptional regulator
BKP58_11280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP58_11285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP58_11290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP58_11295	COG2819	hydrolase of the alpha beta superfamily
BKP58_11300	COG0385	Bile acid
BKP58_11305	COG0659	secondary active sulfate transmembrane transporter activity
BKP58_11390	COG0726	polysaccharide deacetylase
BKP58_11395	COG2194	sulfuric ester hydrolase activity
BKP58_11405	COG0489	protein tyrosine kinase activity
BKP58_11410	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP58_11420	COG2226	methyltransferase
BKP58_11430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BKP58_11435	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKP58_11440	COG0101	tRNA pseudouridine synthase activity
BKP58_11445	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BKP58_11450	COG1122	ATPase activity
BKP58_11455	COG1122	ATPase activity
BKP58_11460	COG0203	ribosomal protein L17
BKP58_11465	COG0202	RNA polymerase activity
BKP58_11470	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKP58_11475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKP58_11480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BKP58_11485	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKP58_11490	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BKP58_11495	COG0024	Methionine aminopeptidase
BKP58_11500	COG0563	adenylate kinase activity
BKP58_11505	COG0201	protein transport
BKP58_11510	COG0200	Binds to the 23S rRNA
BKP58_11515	COG1841	ribosomal large subunit assembly
BKP58_11520	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKP58_11525	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BKP58_11530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKP58_11535	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKP58_11545	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKP58_11555	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKP58_11560	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKP58_11565	COG0255	Belongs to the universal ribosomal protein uL29 family
BKP58_11570	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKP58_11575	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKP58_11580	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BKP58_11585	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BKP58_11590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BKP58_11595	COG0089	rRNA binding
BKP58_11600	COG0088	Forms part of the polypeptide exit tunnel
BKP58_11605	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKP58_11610	COG0051	transcription antitermination factor activity, RNA binding
BKP58_11615	COG0596	Alpha beta hydrolase
BKP58_11620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKP58_11625	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKP58_11630	COG0049	tRNA binding
BKP58_11635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKP58_11640	COG1358	cellular component organization or biogenesis
BKP58_11645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKP58_11650	COG0085	RNA polymerase activity
BKP58_11655	COG2813	Specifically methylates the guanine in position
BKP58_11660	COG0222	ribosome binding
BKP58_11665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKP58_11670	COG0081	regulation of translation
BKP58_11675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKP58_11680	COG0250	Participates in transcription elongation, termination and antitermination
BKP58_11685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKP58_11690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKP58_11695	COG1595	DNA-templated transcription, initiation
BKP58_11700	COG3688	RNA-binding protein containing a PIN domain
BKP58_11705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKP58_11710	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BKP58_11715	COG0215	cysteine-tRNA ligase activity
BKP58_11720	COG1045	serine acetyltransferase
BKP58_11730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKP58_11735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BKP58_11740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BKP58_11745	COG4956	integral membrane protein (PIN domain superfamily)
BKP58_11750	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BKP58_11755	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BKP58_11760	COG0542	response to heat
BKP58_11765	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BKP58_11770	COG3880	PFAM UvrB UvrC protein
BKP58_11775	COG4463	regulation of RNA biosynthetic process
BKP58_11855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKP58_11860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKP58_11865	COG1396	sequence-specific DNA binding
BKP58_11870	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKP58_11875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BKP58_11880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKP58_11885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKP58_11890	COG0512	Glutamine amidotransferase of anthranilate synthase
BKP58_11895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKP58_11900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKP58_11905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKP58_11910	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BKP58_11915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BKP58_11920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKP58_11930	COG0037	tRNA processing
BKP58_11935	COG0515	serine threonine protein kinase
BKP58_11940	COG2304	oxidoreductase activity
BKP58_11945	COG2208	phosphoserine phosphatase activity
BKP58_11960	COG1098	S1 RNA binding domain
BKP58_11965	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BKP58_11980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BKP58_11985	COG3956	TIGRFAM MazG family protein
BKP58_11990	COG2244	polysaccharide biosynthetic process
BKP58_11995	COG2002	toxin-antitoxin pair type II binding
BKP58_12000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKP58_12010	COG0193	aminoacyl-tRNA hydrolase activity
BKP58_12015	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BKP58_12020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKP58_12025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKP58_12035	COG2088	sporulation resulting in formation of a cellular spore
BKP58_12040	COG0251	oxidation-reduction process
BKP58_12045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKP58_12050	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKP58_12060	COG4466	Protein conserved in bacteria
BKP58_12070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKP58_12075	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BKP58_12080	COG3583	domain protein
BKP58_12080	COG3584	3D domain protein
BKP58_12085	COG0084	hydrolase, TatD family'
BKP58_12090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP58_12090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP58_12095	COG2002	toxin-antitoxin pair type II binding
BKP58_12100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BKP58_12105	COG2827	Endonuclease containing a URI domain
BKP58_12110	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BKP58_12115	COG4467	Involved in initiation control of chromosome replication
BKP58_12120	COG1774	PSP1 C-terminal conserved region
BKP58_12125	COG0470	DNA polymerase III
BKP58_12130	COG1728	Protein conserved in bacteria
BKP58_12135	COG3870	Protein conserved in bacteria
BKP58_12140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BKP58_12145	COG1982	Orn Lys Arg decarboxylase major
BKP58_12150	COG3853	Toxic anion resistance protein (TelA)
BKP58_12155	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BKP58_12200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKP58_12205	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKP58_12210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKP58_12220	COG0590	tRNA wobble adenosine to inosine editing
BKP58_12225	COG1335	isochorismatase
BKP58_12230	COG3858	chitin binding
BKP58_12230	COG1388	LysM domain
BKP58_12235	COG1428	Deoxynucleoside kinase
BKP58_12240	COG1428	Deoxynucleoside kinase
BKP58_12250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKP58_12255	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BKP58_12260	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BKP58_12265	COG1686	Belongs to the peptidase S11 family
BKP58_12270	COG0517	IMP dehydrogenase activity
BKP58_12270	COG0516	GMP reductase activity
BKP58_12305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKP58_12310	COG0187	DNA topoisomerase II activity
BKP58_12320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKP58_12325	COG2501	S4 domain
BKP58_12330	COG0592	DNA-directed DNA polymerase activity
BKP58_12335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKP58_12340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BKP58_12345	COG0594	ribonuclease P activity
BKP58_12350	COG0706	membrane insertase activity
BKP58_12355	COG1847	R3H domain protein
BKP58_12360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BKP58_12365	COG0445	tRNA wobble uridine modification
BKP58_12370	COG0357	Ribosomal RNA small subunit methyltransferase G
BKP58_12375	COG1475	DNA binding
BKP58_12385	COG1192	Involved in chromosome partitioning
BKP58_12390	COG1475	DNA binding
BKP58_12400	COG3949	Membrane
BKP58_12405	COG4481	Protein conserved in bacteria
BKP58_12410	COG0243	molybdopterin cofactor binding
BKP58_12415	COG0012	GTP binding
BKP58_12420	COG0360	Binds together with S18 to 16S ribosomal RNA
BKP58_12425	COG0629	single-stranded DNA binding
BKP58_12430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKP58_12435	COG0708	Exodeoxyribonuclease III
BKP58_12450	COG0542	response to heat
BKP58_12455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKP58_12465	COG2814	Major facilitator Superfamily
BKP58_12465	COG0477	Major facilitator Superfamily
BKP58_12470	COG1266	CAAX protease self-immunity
BKP58_12475	COG1331	Highly conserved protein containing a thioredoxin domain
BKP58_12480	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BKP58_12485	COG1331	Highly conserved protein containing a thioredoxin domain
BKP58_12490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKP58_12495	COG2315	Protein conserved in bacteria
BKP58_12500	COG0456	acetyltransferase
BKP58_12505	COG2364	Membrane
BKP58_12510	COG2153	protein acetylation
BKP58_12515	COG1846	Transcriptional regulator
BKP58_12530	COG1357	PFAM Pentapeptide repeats (8 copies)
BKP58_12535	COG4319	ketosteroid isomerase
BKP58_12545	COG0789	Transcriptional regulator
BKP58_12545	COG4978	Transcriptional regulator
BKP58_12550	COG2271	Major facilitator Superfamily
BKP58_12565	COG1227	inorganic diphosphatase activity
BKP58_12570	COG1733	regulation of RNA biosynthetic process
BKP58_12585	COG4241	membrane
BKP58_12590	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BKP58_12595	COG0359	binds to the 23S rRNA
BKP58_12600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKP58_12605	COG2807	transmembrane transport
BKP58_12610	COG3093	addiction module antidote protein HigA
BKP58_12630	COG0305	Participates in initiation and elongation during chromosome replication
BKP58_12635	COG0346	lactoylglutathione lyase activity
BKP58_12665	COG0745	RESPONSE REGULATOR receiver
BKP58_12670	COG5002	protein histidine kinase activity
BKP58_12675	COG4863	YycH protein
BKP58_12680	COG4853	Protein conserved in bacteria
BKP58_12685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKP58_12690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP58_12700	COG3829	transcription factor binding
BKP58_12705	COG0640	Transcriptional regulator
BKP58_12710	COG5658	integral membrane protein
BKP58_12730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKP58_12735	COG0833	amino acid
BKP58_12740	COG0010	Belongs to the arginase family
BKP58_12750	COG0457	Tetratricopeptide repeat
BKP58_12755	COG0456	acetyltransferase
BKP58_12760	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BKP58_12780	COG1063	alcohol dehydrogenase
BKP58_12795	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BKP58_12830	COG2963	transposase activity
BKP58_12860	COG0210	DNA helicase
BKP58_12890	COG0071	Belongs to the small heat shock protein (HSP20) family
BKP58_12905	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BKP58_12910	COG1131	(ABC) transporter
BKP58_12920	COG2188	Transcriptional regulator
BKP58_12935	COG2723	6-phospho-beta-galactosidase activity
BKP58_12940	COG3634	alkyl hydroperoxide reductase activity
BKP58_12945	COG0450	alkyl hydroperoxide reductase
BKP58_12950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BKP58_12955	COG2610	gluconate transmembrane transporter activity
BKP58_12960	COG1070	Carbohydrate kinase
BKP58_12965	COG1802	Transcriptional regulator
BKP58_12970	COG1929	Belongs to the glycerate kinase type-1 family
BKP58_12975	COG5039	Polysaccharide pyruvyl transferase
BKP58_12980	COG1346	cytolysis
BKP58_12985	COG1380	Effector of murein hydrolase LrgA
BKP58_12990	COG1846	Transcriptional regulator
BKP58_12995	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_13000	COG1309	transcriptional regulator
BKP58_13005	COG1917	Cupin 2, conserved barrel domain protein
BKP58_13065	COG0326	Molecular chaperone. Has ATPase activity
BKP58_13095	COG0667	Aldo Keto reductase
BKP58_13100	COG1349	DNA-binding transcription factor activity
BKP58_13120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP58_13125	COG3962	Belongs to the TPP enzyme family
BKP58_13130	COG1082	Xylose isomerase domain protein TIM barrel
BKP58_13135	COG2814	Major facilitator Superfamily
BKP58_13140	COG0673	inositol 2-dehydrogenase activity
BKP58_13145	COG1082	Xylose isomerase domain protein TIM barrel
BKP58_13150	COG1082	Xylose isomerase domain protein TIM barrel
BKP58_13155	COG0191	fructose-bisphosphate aldolase activity
BKP58_13160	COG0745	RESPONSE REGULATOR receiver
BKP58_13165	COG2205	protein histidine kinase activity
BKP58_13180	COG5294	Protein conserved in bacteria
BKP58_13185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP58_13215	COG0561	phosphatase activity
BKP58_13220	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BKP58_13235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP58_13240	COG0765	amino acid transport
BKP58_13245	COG1126	abc transporter atp-binding protein
BKP58_13255	COG2079	MmgE PrpD family protein
BKP58_13260	COG3192	ethanolamine utilization protein
BKP58_13270	COG2390	Transcriptional regulator
BKP58_13275	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BKP58_13280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKP58_13285	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BKP58_13300	COG3507	Belongs to the glycosyl hydrolase 43 family
BKP58_13305	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BKP58_13310	COG0494	nUDIX hydrolase
BKP58_13330	COG5444	nuclease activity
BKP58_13340	COG5444	nuclease activity
BKP58_13350	COG1263	PTS System
BKP58_13350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP58_13350	COG2190	(PTS) system
BKP58_13360	COG0589	response to stress
BKP58_13375	COG0697	spore germination
BKP58_13490	COG2755	lipolytic protein G-D-S-L family
BKP58_13490	COG3401	FG-GAP repeat protein
BKP58_13495	COG0513	Belongs to the DEAD box helicase family
BKP58_13500	COG2270	Major facilitator Superfamily
BKP58_13510	COG3711	transcriptional antiterminator
BKP58_13515	COG2273	Hydrolase Family 16
BKP58_13520	COG2851	Citrate transporter
BKP58_13525	COG0693	protein deglycase activity
BKP58_13525	COG0753	catalase activity
BKP58_13540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKP58_13545	COG0500	methyltransferase
BKP58_13555	COG2610	gluconate transmembrane transporter activity
BKP58_13560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BKP58_13565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BKP58_13570	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_13575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKP58_13580	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKP58_13585	COG4894	glucomannan catabolic process
BKP58_13600	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKP58_13605	COG2197	response regulator
BKP58_13610	COG4585	Histidine kinase
BKP58_13620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKP58_13630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP58_13635	COG1012	belongs to the aldehyde dehydrogenase family
BKP58_13640	COG2508	Transcriptional regulator
BKP58_13645	COG3842	ATPase activity
BKP58_13650	COG0726	polysaccharide deacetylase
BKP58_13660	COG0501	Belongs to the peptidase M48B family
BKP58_13665	COG3493	citrate carrier protein
BKP58_13670	COG1271	oxidase subunit
BKP58_13675	COG1294	oxidase, subunit
BKP58_13680	COG4988	ABC transporter
BKP58_13685	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BKP58_13690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BKP58_13695	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BKP58_13700	COG1595	DNA-templated transcription, initiation
BKP58_13720	COG1131	(ABC) transporter
BKP58_13725	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKP58_13730	COG2814	Major facilitator Superfamily
BKP58_13735	COG0753	catalase activity
BKP58_13740	COG2094	Belongs to the DNA glycosylase MPG family
BKP58_13750	COG3711	transcriptional antiterminator
BKP58_13750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP58_13755	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP58_13760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP58_13765	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP58_13770	COG1486	melibiose metabolic process
BKP58_13775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKP58_13785	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BKP58_13790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKP58_13795	COG1696	Membrane protein involved in D-alanine export
BKP58_13800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKP58_13815	COG1575	Belongs to the MenA family. Type 1 subfamily
BKP58_13820	COG2801	Transposase and inactivated derivatives
BKP58_13830	COG2357	RelA SpoT domain protein
BKP58_13835	COG2234	aminopeptidase activity
BKP58_13840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKP58_13845	COG1846	Transcriptional regulator
BKP58_13850	COG5522	Integral membrane protein (intg_mem_TP0381)
BKP58_13855	COG1442	glycosyl transferase family 8
BKP58_13860	COG3711	transcriptional antiterminator
BKP58_13865	COG1263	PTS System
BKP58_13865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP58_13875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP58_13885	COG0346	lactoylglutathione lyase activity
BKP58_13890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BKP58_13895	COG4895	conserved protein (DUF2196)
BKP58_13900	COG2814	Major facilitator Superfamily
BKP58_13905	COG1346	cytolysis
BKP58_13910	COG1380	Effector of murein hydrolase LrgA
BKP58_13915	COG0583	DNA-binding transcription factor activity
BKP58_13920	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BKP58_13925	COG0352	thiamine-phosphate diphosphorylase activity
BKP58_13930	COG0672	)-iron permease
BKP58_13935	COG2822	iron ion transport
BKP58_13940	COG2837	iron assimilation
BKP58_13945	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BKP58_13950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP58_13955	COG3162	membrane
BKP58_13970	COG2246	polysaccharide biosynthetic process
BKP58_13975	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BKP58_13980	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BKP58_13985	COG2261	transglycosylase associated protein
BKP58_13990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKP58_13995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKP58_14000	COG1845	cytochrome c oxidase, subunit III
BKP58_14005	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BKP58_14020	COG0772	Belongs to the SEDS family
BKP58_14025	COG0778	Nitroreductase
BKP58_14030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP58_14035	COG1404	Belongs to the peptidase S8 family
BKP58_14050	COG2116	formate transmembrane transporter activity
BKP58_14055	COG1263	PTS System
BKP58_14055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP58_14060	COG1621	beta-fructofuranosidase activity
BKP58_14070	COG0351	phosphomethylpyrimidine kinase
BKP58_14075	COG1216	Glycosyl transferase, family 2
BKP58_14080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BKP58_14085	COG1012	belongs to the aldehyde dehydrogenase family
BKP58_14095	COG2233	PERMEase
BKP58_14100	COG2363	Small membrane protein
BKP58_14115	COG0463	Glycosyl transferase, family 2
BKP58_14120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKP58_14125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKP58_14130	COG0456	acetyltransferase
BKP58_14135	COG2089	acid synthase
BKP58_14140	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BKP58_14145	COG3980	spore coat polysaccharide biosynthesis protein
BKP58_14150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BKP58_14155	COG1088	dTDP-glucose 4,6-dehydratase activity
BKP58_14160	COG1091	dTDP-4-dehydrorhamnose reductase activity
BKP58_14165	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BKP58_14175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKP58_14180	COG1012	belongs to the aldehyde dehydrogenase family
BKP58_14185	COG4187	Peptidase family M20/M25/M40
BKP58_14190	COG0833	amino acid
BKP58_14195	COG2814	Major facilitator Superfamily
BKP58_14200	COG0077	Prephenate dehydratase
BKP58_14205	COG1917	Cupin 2, conserved barrel domain protein
BKP58_14210	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_14215	COG0151	Belongs to the GarS family
BKP58_14220	COG2814	Major facilitator Superfamily
BKP58_14225	COG0436	Aminotransferase
BKP58_14230	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_14240	COG0280	phosphate acetyltransferase
BKP58_14245	COG0583	DNA-binding transcription factor activity
BKP58_14250	COG0095	Lipoate-protein ligase
BKP58_14255	COG0697	spore germination
BKP58_14265	COG4844	belongs to the
BKP58_14270	COG1078	dGTPase activity
BKP58_14275	COG3465	dGTPase activity
BKP58_14280	COG1959	2 iron, 2 sulfur cluster binding
BKP58_14285	COG0477	Major facilitator Superfamily
BKP58_14295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKP58_14300	COG1846	Transcriptional regulator
BKP58_14305	COG1942	4-Oxalocrotonate Tautomerase
BKP58_14310	COG1994	Peptidase M50
BKP58_14325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP58_14330	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BKP58_14335	COG0010	Belongs to the arginase family
BKP58_14350	COG0457	Tetratricopeptide repeat
BKP58_14360	COG3391	amine dehydrogenase activity
BKP58_14365	COG3391	amine dehydrogenase activity
BKP58_14375	COG0612	Peptidase, M16
BKP58_14380	COG0612	Peptidase, M16
BKP58_14385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKP58_14390	COG1131	(ABC) transporter
BKP58_14400	COG0535	radical SAM domain protein
BKP58_14410	COG4506	Protein conserved in bacteria
BKP58_14415	COG0018	arginyl-trna synthetase
BKP58_14420	COG2223	nitrite transmembrane transporter activity
BKP58_14425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKP58_14435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKP58_14440	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BKP58_14445	COG1140	nitrate reductase beta subunit
BKP58_14450	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BKP58_14455	COG2181	nitrate reductase activity
BKP58_14460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKP58_14470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKP58_14480	COG4294	response to UV
BKP58_14485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKP58_14490	COG2181	nitrate reductase activity
BKP58_14490	COG0247	lactate metabolic process
BKP58_14495	COG1960	acyl-CoA dehydrogenase activity
BKP58_14500	COG3343	RNA polymerase activity
BKP58_14505	COG0504	CTP synthase activity
BKP58_14510	COG4821	SIS domain
BKP58_14515	COG2204	response regulator
BKP58_14520	COG0191	fructose-bisphosphate aldolase activity
BKP58_14525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BKP58_14530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKP58_14535	COG1494	fructose-1,6-bisphosphatase
BKP58_14545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKP58_14550	COG0254	rRNA binding
BKP58_14555	COG1435	thymidine kinase activity
BKP58_14560	COG0281	malic enzyme
BKP58_14565	COG0679	Auxin Efflux Carrier
BKP58_14570	COG0789	Transcriptional regulator
BKP58_14575	COG0346	lactoylglutathione lyase activity
BKP58_14580	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKP58_14585	COG2890	protein-(glutamine-N5) methyltransferase activity
BKP58_14605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BKP58_14610	COG0009	L-threonylcarbamoyladenylate synthase
BKP58_14615	COG1971	Probably functions as a manganese efflux pump
BKP58_14620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKP58_14625	COG0698	ribose 5-phosphate isomerase
BKP58_14630	COG4475	Protein of unknown function (DUF436)
BKP58_14635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKP58_14640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BKP58_14650	COG0356	it plays a direct role in the translocation of protons across the membrane
BKP58_14655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKP58_14665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKP58_14670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKP58_14675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BKP58_14680	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKP58_14685	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKP58_14690	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKP58_14700	COG4836	Membrane
BKP58_14710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKP58_14715	COG2385	sporulation resulting in formation of a cellular spore
BKP58_14720	COG2304	oxidoreductase activity
BKP58_14730	COG2304	oxidoreductase activity
BKP58_14740	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKP58_14745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKP58_14750	COG0457	Tetratricopeptide repeat
BKP58_14755	COG1994	Peptidase M50
BKP58_14760	COG3237	CsbD-like
BKP58_14770	COG0831	urea catabolic process
BKP58_14775	COG0832	Belongs to the urease beta subunit family
BKP58_14780	COG0804	urea catabolic process
BKP58_14785	COG1959	2 iron, 2 sulfur cluster binding
BKP58_14790	COG2910	NAD(P)H-binding
BKP58_14800	COG0789	Transcriptional regulator
BKP58_14805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKP58_14815	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BKP58_14825	COG1247	-acetyltransferase
BKP58_14830	COG0739	heme binding
BKP58_14840	COG0671	phosphoesterase, PA-phosphatase related
BKP58_14845	COG0347	Belongs to the P(II) protein family
BKP58_14850	COG0004	ammonium transporteR
BKP58_14860	COG1335	isochorismatase
BKP58_14865	COG0477	Major facilitator Superfamily
BKP58_14870	COG1953	Uracil, thiamine, allantoin
BKP58_14875	COG3420	alginic acid biosynthetic process
BKP58_14880	COG2814	Major facilitator Superfamily
BKP58_14885	COG1846	Transcriptional regulator
BKP58_14890	COG1609	Transcriptional regulator
BKP58_14895	COG1077	Cell shape determining protein MreB Mrl
BKP58_14900	COG4786	Flagellar basal body rod
BKP58_14905	COG4786	Flagellar basal body rod
BKP58_14910	COG0457	Tetratricopeptide repeat
BKP58_14915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKP58_14920	COG1970	mechanosensitive ion channel activity
BKP58_14925	COG2972	Histidine kinase
BKP58_14925	COG0745	RESPONSE REGULATOR receiver
BKP58_14935	COG3764	Sortase (surface protein transpeptidase)
BKP58_14950	COG0629	single-stranded DNA binding
BKP58_14955	COG1349	DNA-binding transcription factor activity
BKP58_14960	COG0561	phosphatase activity
BKP58_14965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKP58_14970	COG4715	Zinc finger, swim domain protein
BKP58_14980	COG3944	biosynthesis protein
BKP58_14985	COG0489	protein tyrosine kinase activity
BKP58_14990	COG4464	protein tyrosine phosphatase activity
BKP58_14995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKP58_15015	COG5444	nuclease activity
BKP58_15045	COG0583	DNA-binding transcription factor activity
BKP58_15050	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKP58_15060	COG2059	Chromate
BKP58_15065	COG2059	Chromate
BKP58_15070	COG1522	sequence-specific DNA binding
BKP58_15075	COG0405	Gamma-glutamyltransferase
BKP58_15085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKP58_15095	COG5337	Spore coat protein CotH
BKP58_15110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKP58_15115	COG0583	DNA-binding transcription factor activity
BKP58_15120	COG0028	Belongs to the TPP enzyme family
BKP58_15125	COG3527	Alpha-acetolactate decarboxylase
BKP58_15130	COG2249	NAD(P)H dehydrogenase (quinone) activity
BKP58_15140	COG3103	Sh3 type 3 domain protein
BKP58_15145	COG1879	ABC-type sugar transport system periplasmic component
BKP58_15150	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKP58_15155	COG1129	ABC transporter
BKP58_15160	COG1869	D-ribose catabolic process
BKP58_15165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP58_15170	COG1609	Transcriptional regulator
BKP58_15175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKP58_15185	COG2843	Capsule synthesis protein
BKP58_15195	COG0791	NLP P60 protein
BKP58_15200	COG0561	phosphatase activity
BKP58_15205	COG1316	TRANSCRIPTIONal
BKP58_15220	COG0814	amino acid
BKP58_15225	COG0697	spore germination
BKP58_15235	COG1482	cell wall glycoprotein biosynthetic process
BKP58_15240	COG4193	domain, Protein
BKP58_15245	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKP58_15250	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BKP58_15255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKP58_15260	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKP58_15265	COG0463	Glycosyl transferase, family 2
BKP58_15265	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKP58_15280	COG1682	transport, permease protein
BKP58_15285	COG1134	teichoic acid transport
BKP58_15295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKP58_15300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKP58_15330	COG2247	cell wall binding repeat
BKP58_15330	COG2385	sporulation resulting in formation of a cellular spore
BKP58_15335	COG2247	cell wall binding repeat
BKP58_15335	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP58_15350	COG2244	polysaccharide biosynthetic process
BKP58_15355	COG0438	transferase activity, transferring glycosyl groups
BKP58_15355	COG0297	glycogen (starch) synthase activity
BKP58_15360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKP58_15365	COG3307	-O-antigen
BKP58_15370	COG3206	protein involved in exopolysaccharide biosynthesis
BKP58_15375	COG1215	transferase activity, transferring glycosyl groups
BKP58_15380	COG0438	transferase activity, transferring glycosyl groups
BKP58_15385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP58_15395	COG1131	(ABC) transporter
BKP58_15430	COG1316	TRANSCRIPTIONal
BKP58_15435	COG1739	Uncharacterized protein family UPF0029
BKP58_15440	COG4585	Histidine kinase
BKP58_15445	COG2197	response regulator
BKP58_15450	COG1307	EDD domain protein, DegV family
BKP58_15455	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BKP58_15465	COG1040	competence protein
BKP58_15475	COG2747	anti-sigma28 factor FlgM
BKP58_15480	COG3418	PFAM FlgN family protein
BKP58_15485	COG1256	bacterial-type flagellum assembly
BKP58_15485	COG4786	Flagellar basal body rod
BKP58_15490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKP58_15500	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BKP58_15505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BKP58_15510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKP58_15515	COG1334	flagellar protein FlaG
BKP58_15520	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BKP58_15525	COG1516	flagellar protein fliS
BKP58_15540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKP58_15545	COG0653	protein targeting
BKP58_15550	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKP58_15555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP58_15560	COG2010	Cytochrome c
BKP58_15565	COG2884	Cell division ATP-binding protein ftsE
BKP58_15570	COG2177	Part of the ABC transporter FtsEX involved in
BKP58_15575	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_15575	COG0793	Belongs to the peptidase S41A family
BKP58_15585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP58_15590	COG2814	Major facilitator Superfamily
BKP58_15595	COG1309	transcriptional regulator
BKP58_15600	COG0574	Belongs to the PEP-utilizing enzyme family
BKP58_15600	COG3848	Pyruvate phosphate dikinase
BKP58_15605	COG4897	Protein conserved in bacteria
BKP58_15610	COG0556	nucleotide-excision repair
BKP58_15615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKP58_15620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKP58_15635	COG3595	metallopeptidase activity
BKP58_15640	COG1983	PspC domain protein
BKP58_15645	COG1950	PFAM Membrane protein of
BKP58_15660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BKP58_15670	COG0363	glucosamine-6-phosphate deaminase activity
BKP58_15675	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BKP58_15680	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BKP58_15685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKP58_15690	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKP58_15695	COG0546	phosphoglycolate phosphatase activity
BKP58_15705	COG2801	Transposase and inactivated derivatives
BKP58_15715	COG5297	Belongs to the glycosyl hydrolase family 6
BKP58_15720	COG4990	cell redox homeostasis
BKP58_15725	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BKP58_15730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BKP58_15735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKP58_15740	COG0131	Imidazoleglycerol-phosphate dehydratase
BKP58_15745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKP58_15750	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKP58_15755	COG0107	imidazoleglycerol-phosphate synthase activity
BKP58_15760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKP58_15760	COG0140	phosphoribosyl-ATP diphosphatase activity
BKP58_15780	COG1132	(ABC) transporter
BKP58_15785	COG0457	Tetratricopeptide repeat
BKP58_15790	COG0791	NLP P60 protein
BKP58_15790	COG3883	PFAM NLP P60 protein
BKP58_15795	COG0492	ferredoxin-NADP+ reductase activity
BKP58_15800	COG1051	belongs to the nudix hydrolase family
BKP58_15805	COG1660	Displays ATPase and GTPase activities
BKP58_15810	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BKP58_15815	COG1481	regulation of sporulation
BKP58_15820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP58_15825	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BKP58_15835	COG0745	RESPONSE REGULATOR receiver
BKP58_15840	COG5002	protein histidine kinase activity
BKP58_15845	COG1136	(ABC) transporter
BKP58_15850	COG0577	efflux transmembrane transporter activity
BKP58_15855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP58_15860	COG0288	reversible hydration of carbon dioxide
BKP58_15865	COG0659	secondary active sulfate transmembrane transporter activity
BKP58_15875	COG1611	Belongs to the LOG family
BKP58_15880	COG1609	Transcriptional regulator
BKP58_15890	COG2182	Extracellular solute-binding protein
BKP58_15895	COG1175	transmembrane transport
BKP58_15900	COG3833	ABC-type maltose transport systems, permease component
BKP58_15905	COG5521	maltodextrose utilization protein MalA
BKP58_15910	COG1554	hydrolase, family 65, central catalytic
BKP58_15915	COG0366	Alpha amylase catalytic
BKP58_15920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKP58_15925	COG0740	serine-type endopeptidase activity
BKP58_15935	COG4974	Belongs to the 'phage' integrase family
BKP58_16035	COG0582	viral genome integration into host DNA
BKP58_16115	COG1705	Flagellar rod assembly protein muramidase FlgJ
BKP58_16150	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKP58_16150	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_16150	COG1388	LysM domain
BKP58_16170	COG1674	ftsk spoiiie
BKP58_16190	COG2076	Multidrug Resistance protein
BKP58_16195	COG2076	Multidrug Resistance protein
BKP58_16200	COG1309	transcriptional regulator
BKP58_16205	COG0531	amino acid
BKP58_16210	COG1621	beta-fructofuranosidase activity
BKP58_16215	COG1621	beta-fructofuranosidase activity
BKP58_16225	COG1794	racemase activity, acting on amino acids and derivatives
BKP58_16235	COG3479	Phenolic acid decarboxylase
BKP58_16245	COG2272	Belongs to the type-B carboxylesterase lipase family
BKP58_16250	COG1396	sequence-specific DNA binding
BKP58_16255	COG3944	biosynthesis protein
BKP58_16260	COG0489	protein tyrosine kinase activity
BKP58_16265	COG1086	Polysaccharide biosynthesis protein
BKP58_16270	COG0438	transferase activity, transferring glycosyl groups
BKP58_16275	COG1215	transferase activity, transferring glycosyl groups
BKP58_16280	COG0438	transferase activity, transferring glycosyl groups
BKP58_16290	COG1216	Glycosyl transferase, family 2
BKP58_16295	COG5039	Polysaccharide pyruvyl transferase
BKP58_16300	COG1216	Glycosyl transferase, family 2
BKP58_16305	COG2244	polysaccharide biosynthetic process
BKP58_16310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKP58_16315	COG0110	maltose O-acetyltransferase activity
BKP58_16320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKP58_16325	COG5039	Polysaccharide pyruvyl transferase
BKP58_16335	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKP58_16340	COG1620	l-lactate permease
BKP58_16345	COG2186	Transcriptional regulator
BKP58_16350	COG1609	Transcriptional regulator
BKP58_16355	COG2182	Extracellular solute-binding protein
BKP58_16360	COG1175	transmembrane transport
BKP58_16365	COG3833	ABC-type maltose transport systems, permease component
BKP58_16370	COG1874	Beta-galactosidase
BKP58_16375	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BKP58_16380	COG2208	phosphoserine phosphatase activity
BKP58_16385	COG0596	Alpha beta hydrolase
BKP58_16405	COG1131	(ABC) transporter
BKP58_16410	COG0842	Transport permease protein
BKP58_16415	COG4585	Histidine kinase
BKP58_16420	COG2197	response regulator
BKP58_16425	COG0247	lactate metabolic process
BKP58_16430	COG1139	Iron-sulfur cluster binding protein
BKP58_16435	COG1556	Lactate utilization protein
BKP58_16445	COG1113	amino acid transport
BKP58_16450	COG0697	spore germination
BKP58_16455	COG0583	DNA-binding transcription factor activity
BKP58_16460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP58_16465	COG1609	Transcriptional regulator
BKP58_16470	COG2814	Major facilitator Superfamily
BKP58_16475	COG2390	Transcriptional regulator
BKP58_16480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKP58_16490	COG0126	phosphoglycerate kinase activity
BKP58_16495	COG0149	triose-phosphate isomerase activity
BKP58_16500	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BKP58_16505	COG0148	phosphopyruvate hydratase activity
BKP58_16510	COG0456	acetyltransferase
BKP58_16515	COG4640	response to antibiotic
BKP58_16520	COG3064	Membrane
BKP58_16530	COG2095	MarC family integral membrane protein
BKP58_16535	COG1510	regulation of RNA biosynthetic process
BKP58_16540	COG1125	glycine betaine transport
BKP58_16540	COG0517	IMP dehydrogenase activity
BKP58_16545	COG1174	glycine betaine transport
BKP58_16550	COG1732	Glycine betaine
BKP58_16555	COG1174	glycine betaine transport
BKP58_16560	COG1510	regulation of RNA biosynthetic process
BKP58_16565	COG0517	IMP dehydrogenase activity
BKP58_16565	COG1125	glycine betaine transport
BKP58_16570	COG1174	glycine betaine transport
BKP58_16575	COG1732	Glycine betaine
BKP58_16580	COG1174	glycine betaine transport
BKP58_16585	COG0840	transmembrane signaling receptor activity
BKP58_16590	COG1733	regulation of RNA biosynthetic process
BKP58_16595	COG1396	sequence-specific DNA binding
BKP58_16600	COG1396	sequence-specific DNA binding
BKP58_16605	COG1476	TRANSCRIPTIONal
BKP58_16610	COG0596	Alpha beta hydrolase
BKP58_16615	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKP58_16620	COG1647	Serine aminopeptidase, S33
BKP58_16625	COG0557	exoribonuclease II activity
BKP58_16630	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BKP58_16850	COG1705	Flagellar rod assembly protein muramidase FlgJ
BKP58_16850	COG3942	CHAP domain
BKP58_16870	COG4824	toxin secretion phage lysis holin
BKP58_16875	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_16875	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKP58_16890	COG5444	nuclease activity
BKP58_16900	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_16905	COG1309	transcriptional regulator
BKP58_16910	COG2076	Multidrug Resistance protein
BKP58_16920	COG1289	transmembrane transporter activity
BKP58_16930	COG0673	inositol 2-dehydrogenase activity
BKP58_16935	COG1937	Protein conserved in bacteria
BKP58_16940	COG2608	mercury ion transmembrane transporter activity
BKP58_16945	COG2217	Heavy metal translocating P-type atpase
BKP58_16950	COG2217	Heavy metal translocating P-type atpase
BKP58_16955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BKP58_16960	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BKP58_16965	COG2860	membrane
BKP58_16975	COG3973	AAA domain
BKP58_16980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKP58_16985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKP58_16990	COG0025	NhaP-type Na H and K H
BKP58_17000	COG0656	L-ascorbic acid biosynthetic process
BKP58_17005	COG4149	molybdate abc transporter
BKP58_17010	COG0725	ABC transporter, periplasmic molybdate-binding protein
BKP58_17015	COG1910	domain protein
BKP58_17020	COG1368	sulfuric ester hydrolase activity
BKP58_17025	COG1988	membrane-bound metal-dependent
BKP58_17035	COG0531	amino acid
BKP58_17045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP58_17050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP58_17055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP58_17060	COG1120	ATPase activity
BKP58_17065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKP58_17070	COG1136	(ABC) transporter
BKP58_17075	COG0577	efflux transmembrane transporter activity
BKP58_17085	COG2140	Oxalate decarboxylase
BKP58_17105	COG0745	RESPONSE REGULATOR receiver
BKP58_17110	COG2205	protein histidine kinase activity
BKP58_17115	COG3386	PFAM SMP-30 Gluconolaconase
BKP58_17120	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_17125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP58_17130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP58_17135	COG1120	ATPase activity
BKP58_17140	COG2096	Adenosyltransferase
BKP58_17145	COG2814	Major facilitator Superfamily
BKP58_17150	COG4758	membrane
BKP58_17155	COG1842	Phage shock protein A
BKP58_17160	COG3595	metallopeptidase activity
BKP58_17165	COG4758	membrane
BKP58_17170	COG4585	Histidine kinase
BKP58_17175	COG2197	response regulator
BKP58_17185	COG0814	amino acid
BKP58_17190	COG0697	spore germination
BKP58_17200	COG0114	fumarate hydratase activity
BKP58_17205	COG1309	transcriptional regulator
BKP58_17215	COG2770	Histidine kinase
BKP58_17215	COG2205	protein histidine kinase activity
BKP58_17220	COG0745	RESPONSE REGULATOR receiver
BKP58_17225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP58_17230	COG0783	Belongs to the Dps family
BKP58_17280	COG1131	(ABC) transporter
BKP58_17300	COG1120	ATPase activity
BKP58_17310	COG0583	DNA-binding transcription factor activity
BKP58_17315	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_17320	COG1942	4-Oxalocrotonate Tautomerase
BKP58_17325	COG0477	Major facilitator Superfamily
BKP58_17330	COG1846	Transcriptional regulator
BKP58_17335	COG5577	PFAM Coat F domain
BKP58_17355	COG1024	Enoyl-CoA hydratase
BKP58_17355	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP58_17360	COG0183	Belongs to the thiolase family
BKP58_17365	COG1960	acyl-CoA dehydrogenase activity
BKP58_17370	COG1393	Belongs to the ArsC family
BKP58_17375	COG0509	glycine decarboxylation via glycine cleavage system
BKP58_17385	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BKP58_17390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP58_17400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKP58_17405	COG2011	ABC-type metal ion transport system permease component
BKP58_17410	COG1464	Belongs to the NlpA lipoprotein family
BKP58_17425	COG0396	ATPase activity
BKP58_17430	COG0719	Fe-S assembly protein
BKP58_17435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKP58_17440	COG0822	iron-sulfur transferase activity
BKP58_17445	COG0719	Fe-S assembly protein
BKP58_17450	COG0640	Transcriptional regulator
BKP58_17455	COG0346	lactoylglutathione lyase activity
BKP58_17470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP58_17475	COG0322	excinuclease ABC activity
BKP58_17480	COG2222	sugar isomerase
BKP58_17485	COG1653	transport
BKP58_17490	COG1175	transmembrane transport
BKP58_17500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP58_17505	COG2188	Transcriptional regulator
BKP58_17510	COG3842	ATPase activity
BKP58_17515	COG2356	endonuclease I
BKP58_17525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKP58_17530	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKP58_17535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BKP58_17540	COG2068	MobA-Related Protein
BKP58_17545	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKP58_17550	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKP58_17555	COG2080	2 iron, 2 sulfur cluster binding
BKP58_17565	COG2351	hydroxyisourate hydrolase activity
BKP58_17570	COG3195	allantoin biosynthetic process
BKP58_17570	COG3648	Uricase
BKP58_17575	COG2233	PERMEase
BKP58_17580	COG2233	PERMEase
BKP58_17585	COG2508	Transcriptional regulator
BKP58_17590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKP58_17600	COG1801	Protein of unknown function DUF72
BKP58_17605	COG0730	response to heat
BKP58_17610	COG0737	Belongs to the 5'-nucleotidase family
BKP58_17615	COG3377	Domain of unknown function (DUF1805)
BKP58_17625	COG0739	heme binding
BKP58_17630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKP58_17640	COG4470	Protein conserved in bacteria
BKP58_17645	COG2445	Protein of unknown function DUF86
BKP58_17655	COG0647	UMP catabolic process
BKP58_17660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BKP58_17665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKP58_17670	COG0460	homoserine dehydrogenase
BKP58_17675	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKP58_17680	COG0083	homoserine kinase activity
BKP58_17685	COG1506	peptidase
BKP58_17685	COG0823	Involved in the tonB-independent uptake of proteins
BKP58_17685	COG4946	Tricorn protease homolog
BKP58_17690	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BKP58_17695	COG4837	Protein of unknown function (DUF1462)
BKP58_17700	COG1252	NADH dehydrogenase
BKP58_17705	COG4844	belongs to the
BKP58_17710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKP58_17715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BKP58_17720	COG0316	Belongs to the HesB IscA family
BKP58_17725	COG4974	Belongs to the 'phage' integrase family
BKP58_17735	COG0582	viral genome integration into host DNA
BKP58_17830	COG0456	acetyltransferase
BKP58_17835	COG2808	Putative FMN-binding domain
BKP58_17840	COG0516	GMP reductase activity
BKP58_17850	COG0492	ferredoxin-NADP+ reductase activity
BKP58_17855	COG1252	NADH dehydrogenase
BKP58_17870	COG3584	3D domain protein
BKP58_17875	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BKP58_17880	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKP58_17885	COG2056	Na+-H+ antiporter family
BKP58_17890	COG1268	BioY protein
BKP58_17895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKP58_17900	COG2819	hydrolase of the alpha beta superfamily
BKP58_17905	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_17910	COG1169	isochorismate synthase
BKP58_17915	COG1021	2,3-dihydroxybenzoate-AMP ligase
BKP58_17920	COG1535	isochorismatase
BKP58_17920	COG3433	isochorismatase activity
BKP58_17925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKP58_17930	COG3251	PFAM MbtH domain protein
BKP58_17935	COG5634	Uncharacterized conserved protein (DUF2278)
BKP58_17940	COG0686	Belongs to the AlaDH PNT family
BKP58_17945	COG2508	Transcriptional regulator
BKP58_17945	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BKP58_17950	COG4842	Belongs to the WXG100 family
BKP58_17955	COG5417	Belongs to the EsaB family
BKP58_17960	COG4499	WXG100 protein secretion system (Wss), protein YukC
BKP58_17965	COG0433	COG0433 Predicted ATPase
BKP58_17965	COG1674	ftsk spoiiie
BKP58_17970	COG1511	domain protein
BKP58_17980	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_17985	COG1418	mRNA catabolic process
BKP58_18000	COG0628	permease
BKP58_18015	COG5506	Protein of unknown function (DUF1694)
BKP58_18020	COG1335	isochorismatase
BKP58_18025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BKP58_18030	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BKP58_18045	COG0142	geranyltranstransferase activity
BKP58_18055	COG4585	Histidine kinase
BKP58_18060	COG2197	response regulator
BKP58_18065	COG2050	protein possibly involved in aromatic compounds catabolism
BKP58_18070	COG1320	monovalent cation:proton antiporter activity
BKP58_18075	COG2212	antiporter activity
BKP58_18080	COG1863	multisubunit Na H antiporter MnhE subunit
BKP58_18085	COG0651	ATP synthesis coupled electron transport
BKP58_18090	COG1006	Multisubunit Na H antiporter MnhC subunit
BKP58_18095	COG2111	Na H antiporter
BKP58_18100	COG2111	Na H antiporter
BKP58_18100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKP58_18110	COG3493	citrate carrier protein
BKP58_18135	COG4565	transcriptional regulatory protein
BKP58_18140	COG3290	protein histidine kinase activity
BKP58_18150	COG3011	Protein conserved in bacteria
BKP58_18155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP58_18160	COG2814	Major facilitator Superfamily
BKP58_18170	COG5018	Exonuclease
BKP58_18180	COG2205	protein histidine kinase activity
BKP58_18185	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BKP58_18195	COG2267	carboxylic ester hydrolase activity
BKP58_18200	COG1522	sequence-specific DNA binding
BKP58_18205	COG0436	Aminotransferase
BKP58_18210	COG1098	S1 RNA binding domain
BKP58_18215	COG2155	Conserved Protein
BKP58_18220	COG1979	alcohol dehydrogenase
BKP58_18225	COG1979	alcohol dehydrogenase
BKP58_18230	COG0166	Belongs to the GPI family
BKP58_18245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKP58_18260	COG2738	Putative neutral zinc metallopeptidase
BKP58_18265	COG1253	flavin adenine dinucleotide binding
BKP58_18270	COG0366	Alpha amylase catalytic
BKP58_18275	COG0432	Pfam Uncharacterised protein family UPF0047
BKP58_18290	COG0840	transmembrane signaling receptor activity
BKP58_18300	COG0840	transmembrane signaling receptor activity
BKP58_18315	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_18315	COG3347	Dehydrogenase
BKP58_18320	COG1349	DNA-binding transcription factor activity
BKP58_18325	COG1070	Carbohydrate kinase
BKP58_18330	COG3254	rhamnose metabolic process
BKP58_18335	COG4806	L-rhamnose isomerase
BKP58_18340	COG0673	inositol 2-dehydrogenase activity
BKP58_18345	COG0628	permease
BKP58_18350	COG1968	undecaprenyl-diphosphatase activity
BKP58_18360	COG5553	Cysteine dioxygenase type I
BKP58_18365	COG0477	Major facilitator Superfamily
BKP58_18370	COG1705	Flagellar rod assembly protein muramidase FlgJ
BKP58_18375	COG4682	membrane
BKP58_18380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKP58_18385	COG0569	domain protein
BKP58_18395	COG1510	regulation of RNA biosynthetic process
BKP58_18405	COG1454	alcohol dehydrogenase
BKP58_18415	COG2318	DinB family
BKP58_18420	COG1585	Membrane protein implicated in regulation of membrane protease activity
BKP58_18425	COG2268	Band 7 protein
BKP58_18430	COG1247	-acetyltransferase
BKP58_18435	COG3859	Proton-coupled thiamine transporter YuaJ
BKP58_18565	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BKP58_18570	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BKP58_18575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BKP58_18580	COG0297	glycogen (starch) synthase activity
BKP58_18585	COG0058	SHG alpha-glucan phosphorylase activity
BKP58_18590	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BKP58_18595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKP58_18600	COG0438	transferase activity, transferring glycosyl groups
BKP58_18605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKP58_18615	COG0438	transferase activity, transferring glycosyl groups
BKP58_18620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKP58_18625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKP58_18630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKP58_18635	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKP58_18640	COG1169	isochorismate synthase
BKP58_18645	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BKP58_18650	COG0596	Alpha beta hydrolase
BKP58_18655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BKP58_18660	COG0318	PFAM AMP-dependent synthetase and ligase
BKP58_18665	COG4948	Mandelate Racemase Muconate Lactonizing
BKP58_18670	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKP58_18675	COG1121	(ABC) transporter
BKP58_18680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP58_18680	COG1321	iron dependent repressor
BKP58_18685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP58_18695	COG1294	oxidase, subunit
BKP58_18700	COG1271	oxidase subunit
BKP58_18705	COG0254	rRNA binding
BKP58_18710	COG0288	reversible hydration of carbon dioxide
BKP58_18715	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BKP58_18720	COG1854	S-ribosylhomocysteine lyase activity
BKP58_18735	COG0783	Belongs to the Dps family
BKP58_18740	COG4824	toxin secretion phage lysis holin
BKP58_18745	COG0494	nUDIX hydrolase
BKP58_18750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKP58_18755	COG1116	anion transmembrane transporter activity
BKP58_18760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKP58_18765	COG1506	peptidase
BKP58_18775	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BKP58_18780	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKP58_18785	COG0367	asparagine synthase
BKP58_18790	COG1113	amino acid transport
BKP58_18795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BKP58_18800	COG2267	carboxylic ester hydrolase activity
BKP58_18810	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BKP58_18815	COG1242	4 iron, 4 sulfur cluster binding
BKP58_18830	COG1725	Transcriptional regulator
BKP58_18835	COG1131	(ABC) transporter
BKP58_18850	COG1136	(ABC) transporter
BKP58_18855	COG0577	efflux transmembrane transporter activity
BKP58_18860	COG0745	RESPONSE REGULATOR receiver
BKP58_18865	COG2205	protein histidine kinase activity
BKP58_18870	COG1136	(ABC) transporter
BKP58_18875	COG0577	efflux transmembrane transporter activity
BKP58_18880	COG2433	Pfam Transposase IS66
BKP58_18885	COG2814	Major facilitator Superfamily
BKP58_18890	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP58_18890	COG2202	Pas domain
BKP58_18900	COG0495	leucyl-tRNA aminoacylation
BKP58_18905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP58_18910	COG1486	melibiose metabolic process
BKP58_18935	COG1073	alpha beta
BKP58_18940	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BKP58_18945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKP58_18965	COG2124	cytochrome p450
BKP58_18970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKP58_18975	COG0395	ABC-type sugar transport system, permease component
BKP58_18980	COG1653	transport
BKP58_18990	COG4209	transmembrane transport
BKP58_18995	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BKP58_19000	COG1653	transport
BKP58_19020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKP58_19025	COG2081	HI0933 family
BKP58_19030	COG2244	polysaccharide biosynthetic process
BKP58_19035	COG1187	pseudouridine synthase activity
BKP58_19040	COG1349	DNA-binding transcription factor activity
BKP58_19045	COG1131	(ABC) transporter
BKP58_19050	COG4473	ABC transporter
BKP58_19055	COG2252	PERMEase
BKP58_19060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKP58_19065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKP58_19070	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BKP58_19080	COG1597	lipid kinase activity
BKP58_19085	COG1523	belongs to the glycosyl hydrolase 13 family
BKP58_19090	COG0510	thiamine kinase activity
BKP58_19100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKP58_19105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP58_19110	COG0281	malic enzyme
BKP58_19115	COG5584	Small secreted protein
BKP58_19120	COG1363	Peptidase, m42
BKP58_19130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP58_19135	COG4848	Belongs to the UPF0354 family
BKP58_19140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP58_19145	COG1674	ftsk spoiiie
BKP58_19150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKP58_19155	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BKP58_19160	COG4980	gas vesicle protein
BKP58_19165	COG3118	belongs to the thioredoxin family
BKP58_19170	COG1605	Chorismate mutase
BKP58_19170	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BKP58_19175	COG1609	Transcriptional regulator
BKP58_19180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKP58_19185	COG1360	Flagellar Motor Protein
BKP58_19190	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKP58_19195	COG0517	IMP dehydrogenase activity
BKP58_19200	COG0454	-acetyltransferase
BKP58_19205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP58_19210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKP58_19220	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKP58_19225	COG2199	diguanylate cyclase activity
BKP58_19225	COG2203	Gaf domain
BKP58_19230	COG1956	GAF domain-containing protein
BKP58_19235	COG1309	transcriptional regulator
BKP58_19240	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BKP58_19245	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BKP58_19250	COG1114	Component of the transport system for branched-chain amino acids
BKP58_19255	COG1104	cysteine desulfurase activity
BKP58_19260	COG0301	tRNA thio-modification
BKP58_19270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP58_19275	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BKP58_19280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKP58_19285	COG0616	signal peptide processing
BKP58_19290	COG1714	RDD family
BKP58_19300	COG3874	Sporulation protein YtfJ
BKP58_19305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BKP58_19310	COG0827	DNA restriction-modification system
BKP58_19315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKP58_19320	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKP58_19325	COG0137	argininosuccinate synthase activity
BKP58_19330	COG0165	Argininosuccinate lyase
BKP58_19340	COG1028	Short-chain dehydrogenase reductase Sdr
BKP58_19345	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKP58_19355	COG4109	DRTGG domain
BKP58_19365	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BKP58_19385	COG0587	DNA-directed DNA polymerase activity
BKP58_19390	COG0281	malic enzyme
BKP58_19395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKP58_19400	COG0825	malonyl-CoA metabolic process
BKP58_19405	COG0205	6-phosphofructokinase activity
BKP58_19410	COG0469	pyruvate kinase activity
BKP58_19415	COG3030	protein affecting phage T7 exclusion by the F plasmid
BKP58_19420	COG0628	permease
BKP58_19425	COG2707	UPF0756 membrane protein
BKP58_19430	COG0372	Belongs to the citrate synthase family
BKP58_19435	COG0538	isocitrate dehydrogenase activity
BKP58_19440	COG0039	L-malate dehydrogenase activity
BKP58_19445	COG0745	RESPONSE REGULATOR receiver
BKP58_19450	COG5002	protein histidine kinase activity
BKP58_19455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKP58_19455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKP58_19460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKP58_19475	COG0237	dephospho-CoA kinase activity
BKP58_19480	COG0656	L-ascorbic acid biosynthetic process
BKP58_19485	COG2814	Major facilitator Superfamily
BKP58_19490	COG1733	regulation of RNA biosynthetic process
BKP58_19495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKP58_19500	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BKP58_19505	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKP58_19510	COG3611	Membrane attachment protein
BKP58_19515	COG1484	DNA-dependent DNA replication
BKP58_19520	COG0398	Pfam SNARE associated Golgi protein
BKP58_19530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKP58_19540	COG3275	phosphorelay sensor kinase activity
BKP58_19545	COG3279	Response regulator of the LytR AlgR family
BKP58_19550	COG1380	Effector of murein hydrolase LrgA
BKP58_19555	COG1346	cytolysis
BKP58_19565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKP58_19570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKP58_19575	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKP58_19580	COG3326	Membrane
BKP58_19590	COG1363	Peptidase, m42
BKP58_19600	COG2160	L-arabinose isomerase activity
BKP58_19605	COG1069	ribulokinase activity
BKP58_19610	COG0235	Class ii aldolase
BKP58_19615	COG0647	UMP catabolic process
BKP58_19620	COG0371	Dehydrogenase
BKP58_19625	COG1653	transport
BKP58_19630	COG1175	transmembrane transport
BKP58_19635	COG0395	ABC-type sugar transport system, permease component
BKP58_19640	COG3534	alpha-L-arabinofuranosidase
BKP58_19645	COG1966	Carbon starvation protein
BKP58_19650	COG0346	lactoylglutathione lyase activity
BKP58_19655	COG0247	lactate metabolic process
BKP58_19660	COG0277	FAD linked oxidase domain protein
BKP58_19665	COG3835	regulator
BKP58_19675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKP58_19685	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKP58_19690	COG0072	phenylalanine-tRNA ligase activity
BKP58_19690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP58_19695	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKP58_19700	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BKP58_19705	COG1286	toxin biosynthetic process
BKP58_19710	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BKP58_19710	COG1796	DNA polymerase
BKP58_19715	COG1193	negative regulation of DNA recombination
BKP58_19720	COG3766	membrane
BKP58_19725	COG0318	PFAM AMP-dependent synthetase and ligase
BKP58_19730	COG1309	transcriptional regulator
BKP58_19735	COG1024	Enoyl-CoA hydratase
BKP58_19740	COG2086	electron transfer activity
BKP58_19745	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BKP58_19750	COG3534	alpha-L-arabinofuranosidase
BKP58_19755	COG3118	belongs to the thioredoxin family
BKP58_19760	COG0322	excinuclease ABC activity
BKP58_19765	COG0527	aspartate kinase activity
BKP58_19770	COG1719	4-vinyl reductase, 4VR
BKP58_19780	COG2009	succinate dehydrogenase
BKP58_19785	COG1053	succinate dehydrogenase
BKP58_19790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKP58_19795	COG0824	Thioesterase
BKP58_19800	COG2197	response regulator
BKP58_19805	COG1846	Transcriptional regulator
BKP58_19810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKP58_19815	COG5401	PFAM Sporulation and spore germination
BKP58_19820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BKP58_19825	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKP58_19830	COG0622	Phosphoesterase
BKP58_19855	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BKP58_19880	COG2801	Transposase and inactivated derivatives
BKP58_19890	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BKP58_19910	COG0028	Belongs to the TPP enzyme family
BKP58_19915	COG0440	acetolactate synthase activity
BKP58_19920	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKP58_19925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP58_19930	COG0473	3-isopropylmalate dehydrogenase activity
BKP58_19935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKP58_19940	COG0066	3-isopropylmalate dehydratase activity
BKP58_19945	COG0457	Tetratricopeptide repeat
BKP58_19945	COG1477	protein flavinylation
BKP58_19950	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKP58_19955	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKP58_19960	COG0470	DNA polymerase III
BKP58_19960	COG1067	ATP-dependent peptidase activity
BKP58_19965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKP58_19970	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BKP58_19980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BKP58_19985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKP58_19990	COG0181	hydroxymethylbilane synthase activity
BKP58_19995	COG1587	Uroporphyrinogen-III synthase
BKP58_20000	COG0113	porphobilinogen synthase activity
BKP58_20005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKP58_20010	COG1388	LysM domain
BKP58_20015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKP58_20025	COG0525	valine-tRNA ligase activity
BKP58_20030	COG0285	dihydrofolate synthase activity
BKP58_20035	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BKP58_20045	COG0424	maF-like protein
BKP58_20050	COG2003	Belongs to the UPF0758 family
BKP58_20055	COG1077	Cell shape determining protein MreB Mrl
BKP58_20060	COG1792	Involved in formation and maintenance of cell shape
BKP58_20065	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BKP58_20070	COG0850	regulation of cytokinetic process
BKP58_20075	COG2894	cell division
BKP58_20080	COG0739	heme binding
BKP58_20085	COG1994	Peptidase M50
BKP58_20090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKP58_20095	COG2868	ribosomal protein
BKP58_20100	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKP58_20110	COG3290	protein histidine kinase activity
BKP58_20115	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKP58_20120	COG4492	Belongs to the UPF0735 family
BKP58_20125	COG0077	Prephenate dehydratase
BKP58_20130	COG1827	regulation of RNA biosynthetic process
BKP58_20135	COG1104	cysteine desulfurase activity
BKP58_20140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BKP58_20145	COG0157	Belongs to the NadC ModD family
BKP58_20150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BKP58_20155	COG1388	LysM domain
BKP58_20165	COG0217	transcriptional regulatory protein
BKP58_20170	COG1115	amino acid carrier protein
BKP58_20190	COG2112	serine threonine protein kinase
BKP58_20195	COG0673	inositol 2-dehydrogenase activity
BKP58_20200	COG2814	Major facilitator Superfamily
BKP58_20210	COG0632	four-way junction helicase activity
BKP58_20215	COG2255	four-way junction helicase activity
BKP58_20225	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKP58_20230	COG0343	queuine tRNA-ribosyltransferase activity
BKP58_20235	COG1862	Preprotein translocase
BKP58_20245	COG2323	membrane
BKP58_20250	COG2244	polysaccharide biosynthetic process
BKP58_20260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKP58_20260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKP58_20265	COG0490	domain, Protein
BKP58_20270	COG5416	Lipopolysaccharide assembly protein A domain
BKP58_20275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BKP58_20275	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BKP58_20280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKP58_20285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKP58_20290	COG1490	D-aminoacyl-tRNA deacylase activity
BKP58_20295	COG4991	sh3 domain protein
BKP58_20295	COG3103	Sh3 type 3 domain protein
BKP58_20295	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP58_20305	COG0124	histidyl-tRNA synthetase
BKP58_20310	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKP58_20320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BKP58_20325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BKP58_20330	COG1959	2 iron, 2 sulfur cluster binding
BKP58_20335	COG1104	cysteine desulfurase activity
BKP58_20340	COG0482	sulfurtransferase activity
BKP58_20345	COG0457	Tetratricopeptide repeat
BKP58_20350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKP58_20355	COG3881	PFAM PRC-barrel domain
BKP58_20370	COG0765	amino acid transport
BKP58_20375	COG0765	amino acid transport
BKP58_20380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP58_20385	COG1126	abc transporter atp-binding protein
BKP58_20390	COG0628	permease
BKP58_20395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKP58_20400	COG4472	Bacterial protein of unknown function (DUF965)
BKP58_20405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BKP58_20410	COG3906	Belongs to the UPF0473 family
BKP58_20415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKP58_20435	COG0572	uridine kinase
BKP58_20440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKP58_20445	COG0768	penicillin binding
BKP58_20460	COG2226	methyltransferase
BKP58_20465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BKP58_20470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKP58_20475	COG0626	cystathionine gamma-synthase activity
BKP58_20490	COG2427	Protein of unknown function (DUF1641)
BKP58_20495	COG3383	formate dehydrogenase (NAD+) activity
BKP58_20500	COG5609	conserved protein (DUF2294)
BKP58_20505	COG2116	formate transmembrane transporter activity
BKP58_20515	COG2226	methyltransferase
BKP58_20520	COG1309	transcriptional regulator
BKP58_20545	COG1595	DNA-templated transcription, initiation
BKP58_20550	COG1378	Sugar-specific transcriptional regulator TrmB
BKP58_20555	COG1280	lysine exporter protein (LysE YggA)
BKP58_20560	COG1113	amino acid transport
BKP58_20565	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BKP58_20565	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BKP58_20570	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP58_20575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP58_20580	COG3715	PTS system
BKP58_20585	COG3716	PTS system mannose fructose sorbose family IID component
BKP58_20590	COG1621	beta-fructofuranosidase activity
BKP58_20595	COG0693	protein deglycase activity
BKP58_20600	COG1064	alcohol dehydrogenase
BKP58_20610	COG0789	Transcriptional regulator
BKP58_20615	COG5577	PFAM Coat F domain
BKP58_20625	COG1063	alcohol dehydrogenase
BKP58_20630	COG5577	PFAM Coat F domain
BKP58_20640	COG0346	lactoylglutathione lyase activity
BKP58_20645	COG4991	sh3 domain protein
BKP58_20650	COG4991	sh3 domain protein
BKP58_20655	COG0596	Alpha beta hydrolase
BKP58_20660	COG5566	PFAM Mor transcription activator
BKP58_20665	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_20670	COG0667	Aldo Keto reductase
BKP58_20675	COG1595	DNA-templated transcription, initiation
BKP58_20680	COG3443	Belongs to the bacterial solute-binding protein 9 family
BKP58_20695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKP58_20700	COG2070	2-Nitropropane dioxygenase
BKP58_20710	COG2318	DinB family
BKP58_20720	COG1335	isochorismatase
BKP58_20735	COG2124	cytochrome p450
BKP58_20740	COG2732	(Barnase) inhibitor
BKP58_20745	COG1522	sequence-specific DNA binding
BKP58_20755	COG1687	branched-chain amino acid
BKP58_20760	COG1114	Component of the transport system for branched-chain amino acids
BKP58_20770	COG1230	cation diffusion facilitator family transporter
BKP58_20775	COG2072	flavoprotein involved in K transport
BKP58_20780	COG0583	DNA-binding transcription factor activity
BKP58_20785	COG0697	spore germination
BKP58_20795	COG1253	flavin adenine dinucleotide binding
BKP58_20800	COG0456	acetyltransferase
BKP58_20805	COG2814	Major facilitator Superfamily
BKP58_20810	COG4978	Transcriptional regulator
BKP58_20810	COG0789	Transcriptional regulator
BKP58_20920	COG0457	Tetratricopeptide repeat
BKP58_20930	COG0583	DNA-binding transcription factor activity
BKP58_20935	COG0114	fumarate hydratase activity
BKP58_20955	COG3209	COG3209 Rhs family protein
BKP58_20965	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BKP58_20970	COG0398	Pfam SNARE associated Golgi protein
BKP58_20975	COG3409	Peptidoglycan-binding domain 1 protein
BKP58_20975	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKP58_20980	COG2755	lipolytic protein G-D-S-L family
BKP58_20995	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BKP58_21000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BKP58_21005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKP58_21010	COG1534	Rna-binding protein
BKP58_21015	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BKP58_21020	COG1713	HD superfamily hydrolase involved in NAD metabolism
BKP58_21025	COG0799	negative regulation of ribosome biogenesis
BKP58_21030	COG2226	methyltransferase
BKP58_21035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKP58_21040	COG1555	photosystem II stabilization
BKP58_21040	COG1596	polysaccharide export
BKP58_21045	COG2131	deaminase
BKP58_21050	COG0658	competence protein
BKP58_21050	COG2333	competence protein COMEC
BKP58_21060	COG1466	dna polymerase III delta subunit
BKP58_21065	COG0268	Binds directly to 16S ribosomal RNA
BKP58_21070	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BKP58_21075	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP58_21085	COG0481	GTPase activity
BKP58_21090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKP58_21095	COG1420	regulation of RNA biosynthetic process
BKP58_21100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKP58_21105	COG0443	Heat shock 70 kDa protein
BKP58_21110	COG0484	heat shock protein binding
BKP58_21115	COG2264	protein methyltransferase activity
BKP58_21120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BKP58_21125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKP58_21130	COG1283	sodium-dependent phosphate transmembrane transporter activity
BKP58_21135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BKP58_21140	COG1610	YqeY-like protein
BKP58_21145	COG1030	water channel activity
BKP58_21150	COG4864	UPF0365 protein
BKP58_21165	COG0561	phosphatase activity
BKP58_21170	COG1702	phosphate starvation-inducible protein PhoH
BKP58_21180	COG1480	7TM receptor with intracellular HD hydrolase
BKP58_21185	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BKP58_21190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BKP58_21195	COG0295	cytidine deaminase activity
BKP58_21200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKP58_21210	COG1381	Involved in DNA repair and RecF pathway recombination
BKP58_21215	COG0752	glycyl-tRNA synthetase alpha subunit
BKP58_21220	COG0751	glycine-tRNA ligase activity
BKP58_21225	COG0517	IMP dehydrogenase activity
BKP58_21230	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BKP58_21235	COG1671	Belongs to the UPF0178 family
BKP58_21240	COG0358	DNA primase activity
BKP58_21245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKP58_21250	COG2010	Cytochrome c
BKP58_21255	COG2384	SAM-dependent methyltransferase
BKP58_21260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKP58_21265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKP58_21275	COG0513	Belongs to the DEAD box helicase family
BKP58_21280	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BKP58_21290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP58_21295	COG0735	belongs to the Fur family
BKP58_21300	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BKP58_21305	COG4709	membrane
BKP58_21310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BKP58_21315	COG1388	LysM domain
BKP58_21320	COG5521	maltodextrose utilization protein MalA
BKP58_21325	COG2839	Protein conserved in bacteria
BKP58_21330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKP58_21335	COG0477	Major facilitator Superfamily
BKP58_21345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKP58_21350	COG0573	inorganic phosphate transmembrane transporter activity
BKP58_21355	COG0581	inorganic phosphate transmembrane transporter activity
BKP58_21360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKP58_21365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKP58_21370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKP58_21385	COG0438	transferase activity, transferring glycosyl groups
BKP58_21390	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKP58_21395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BKP58_21405	COG0705	Rhomboid family
BKP58_21405	COG0457	Tetratricopeptide repeat
BKP58_21410	COG4483	Protein conserved in bacteria
BKP58_21415	COG1940	carbohydrate kinase activity
BKP58_21420	COG1368	sulfuric ester hydrolase activity
BKP58_21425	COG2866	Carboxypeptidase
BKP58_21435	COG0011	TIGRFAM Protein of
BKP58_21445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP58_21455	COG1393	Belongs to the ArsC family
BKP58_21465	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP58_21470	COG1253	flavin adenine dinucleotide binding
BKP58_21475	COG0598	Magnesium transport protein CorA
BKP58_21480	COG0517	IMP dehydrogenase activity
BKP58_21490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BKP58_21495	COG1459	type II secretion system
BKP58_21500	COG4537	Required for transformation and DNA binding
BKP58_21505	COG4970	Tfp pilus assembly protein FimT
BKP58_21515	COG4940	Competence protein ComGF
BKP58_21540	COG0681	Belongs to the peptidase S26 family
BKP58_21550	COG1396	sequence-specific DNA binding
BKP58_21565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKP58_21570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKP58_21575	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKP58_21580	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKP58_21585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP58_21590	COG0095	Lipoate-protein ligase
BKP58_21595	COG1321	iron dependent repressor
BKP58_21600	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKP58_21610	COG3872	metal-dependent enzyme
BKP58_21620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKP58_21625	COG0006	proline dipeptidase activity
BKP58_21630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKP58_21640	COG3854	ATPases associated with a variety of cellular activities
BKP58_21690	COG0511	ligase activity, forming carbon-carbon bonds
BKP58_21695	COG0439	Biotin carboxylase
BKP58_21700	COG1302	Protein conserved in bacteria
BKP58_21705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKP58_21710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKP58_21715	COG1570	exodeoxyribonuclease VII activity
BKP58_21720	COG1722	exodeoxyribonuclease VII activity
BKP58_21725	COG0142	geranyltranstransferase activity
BKP58_21730	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BKP58_21735	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BKP58_21740	COG1438	arginine binding
BKP58_21745	COG0497	DNA recombination
BKP58_21750	COG0750	zinc metalloprotease
BKP58_21760	COG0745	RESPONSE REGULATOR receiver
BKP58_21770	COG1902	pentaerythritol trinitrate reductase activity
BKP58_21785	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP58_21790	COG0584	glycerophosphoryl diester phosphodiesterase
BKP58_21795	COG0183	Belongs to the thiolase family
BKP58_21800	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP58_21805	COG1960	acyl-CoA dehydrogenase activity
BKP58_21810	COG0372	Belongs to the citrate synthase family
BKP58_21815	COG2079	MmgE PrpD family protein
BKP58_21820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BKP58_21830	COG3829	transcription factor binding
BKP58_21830	COG3290	protein histidine kinase activity
BKP58_21835	COG0280	phosphate acetyltransferase
BKP58_21840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKP58_21845	COG3426	butyrate kinase activity
BKP58_21850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKP58_21855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKP58_21860	COG0022	dehydrogenase e1 component
BKP58_21865	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKP58_21870	COG0789	Transcriptional regulator
BKP58_21870	COG4978	Transcriptional regulator
BKP58_21880	COG1597	lipid kinase activity
BKP58_21890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP58_21895	COG0765	amino acid transport
BKP58_21900	COG1126	abc transporter atp-binding protein
BKP58_21905	COG4129	membrane
BKP58_21910	COG1376	ErfK ybiS ycfS ynhG family protein
BKP58_21920	COG0346	lactoylglutathione lyase activity
BKP58_21930	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKP58_21935	COG3361	conserved protein (COG2071)
BKP58_21940	COG0706	membrane insertase activity
BKP58_21950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKP58_21955	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BKP58_21960	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BKP58_21965	COG1234	tRNA 3'-trailer cleavage
BKP58_21975	COG0596	Alpha beta hydrolase
BKP58_21985	COG1902	pentaerythritol trinitrate reductase activity
BKP58_21990	COG4187	Peptidase family M20/M25/M40
BKP58_21995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKP58_22000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP58_22005	COG0300	oxidoreductase activity
BKP58_22010	COG3048	D-serine ammonia-lyase activity
BKP58_22040	COG3883	PFAM NLP P60 protein
BKP58_22040	COG0791	NLP P60 protein
BKP58_22095	COG0629	single-stranded DNA binding
BKP58_22110	COG0582	viral genome integration into host DNA
BKP58_22140	COG1793	dna ligase
BKP58_22155	COG1525	nuclease
BKP58_22270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKP58_22315	COG0457	Tetratricopeptide repeat