locus-tag	class	description
N8A75_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N8A75_00010	COG0592	DNA-directed DNA polymerase activity
N8A75_00015	COG2501	S4 domain
N8A75_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N8A75_00030	COG0187	DNA topoisomerase II activity
N8A75_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N8A75_00070	COG0516	GMP reductase activity
N8A75_00070	COG0517	IMP dehydrogenase activity
N8A75_00075	COG1686	Belongs to the peptidase S11 family
N8A75_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
N8A75_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
N8A75_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N8A75_00100	COG1428	Deoxynucleoside kinase
N8A75_00105	COG1428	Deoxynucleoside kinase
N8A75_00110	COG1388	LysM domain
N8A75_00110	COG3858	chitin binding
N8A75_00115	COG1335	isochorismatase
N8A75_00120	COG0590	tRNA wobble adenosine to inosine editing
N8A75_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N8A75_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N8A75_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N8A75_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
N8A75_00190	COG3853	Toxic anion resistance protein (TelA)
N8A75_00195	COG1982	Orn Lys Arg decarboxylase major
N8A75_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N8A75_00205	COG3870	Protein conserved in bacteria
N8A75_00210	COG1728	Protein conserved in bacteria
N8A75_00215	COG0470	DNA polymerase III
N8A75_00220	COG1774	PSP1 C-terminal conserved region
N8A75_00225	COG4467	Involved in initiation control of chromosome replication
N8A75_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N8A75_00235	COG2827	Endonuclease containing a URI domain
N8A75_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N8A75_00245	COG2002	toxin-antitoxin pair type II binding
N8A75_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N8A75_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N8A75_00255	COG0084	hydrolase, TatD family'
N8A75_00260	COG3583	domain protein
N8A75_00260	COG3584	3D domain protein
N8A75_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N8A75_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N8A75_00280	COG4466	Protein conserved in bacteria
N8A75_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N8A75_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N8A75_00300	COG0251	oxidation-reduction process
N8A75_00305	COG2088	sporulation resulting in formation of a cellular spore
N8A75_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N8A75_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N8A75_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N8A75_00325	COG0193	aminoacyl-tRNA hydrolase activity
N8A75_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N8A75_00340	COG2002	toxin-antitoxin pair type II binding
N8A75_00345	COG2244	polysaccharide biosynthetic process
N8A75_00350	COG3956	TIGRFAM MazG family protein
N8A75_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N8A75_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N8A75_00375	COG1098	S1 RNA binding domain
N8A75_00390	COG2208	phosphoserine phosphatase activity
N8A75_00395	COG2304	oxidoreductase activity
N8A75_00400	COG0515	serine threonine protein kinase
N8A75_00405	COG0037	tRNA processing
N8A75_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
N8A75_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N8A75_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
N8A75_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N8A75_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N8A75_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N8A75_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N8A75_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
N8A75_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N8A75_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N8A75_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N8A75_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N8A75_00470	COG1396	sequence-specific DNA binding
N8A75_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N8A75_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N8A75_00560	COG4463	regulation of RNA biosynthetic process
N8A75_00565	COG3880	PFAM UvrB UvrC protein
N8A75_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
N8A75_00575	COG0542	response to heat
N8A75_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N8A75_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
N8A75_00590	COG4956	integral membrane protein (PIN domain superfamily)
N8A75_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N8A75_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N8A75_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N8A75_00610	COG1045	serine acetyltransferase
N8A75_00615	COG0215	cysteine-tRNA ligase activity
N8A75_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
N8A75_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N8A75_00630	COG3688	RNA-binding protein containing a PIN domain
N8A75_00635	COG1595	DNA-templated transcription, initiation
N8A75_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N8A75_00650	COG0250	Participates in transcription elongation, termination and antitermination
N8A75_00660	COG0081	regulation of translation
N8A75_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N8A75_00675	COG2813	Specifically methylates the guanine in position
N8A75_00680	COG0085	RNA polymerase activity
N8A75_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N8A75_00690	COG1358	cellular component organization or biogenesis
N8A75_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N8A75_00700	COG0049	tRNA binding
N8A75_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N8A75_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N8A75_00715	COG0596	Alpha beta hydrolase
N8A75_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N8A75_00730	COG0088	Forms part of the polypeptide exit tunnel
N8A75_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N8A75_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N8A75_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N8A75_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N8A75_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N8A75_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N8A75_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N8A75_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N8A75_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N8A75_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N8A75_00820	COG0200	Binds to the 23S rRNA
N8A75_00825	COG0201	protein transport
N8A75_00830	COG0563	adenylate kinase activity
N8A75_00835	COG0024	Methionine aminopeptidase
N8A75_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
N8A75_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N8A75_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N8A75_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N8A75_00865	COG0202	RNA polymerase activity
N8A75_00870	COG0203	ribosomal protein L17
N8A75_00875	COG1122	ATPase activity
N8A75_00880	COG1122	ATPase activity
N8A75_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N8A75_00890	COG0101	tRNA pseudouridine synthase activity
N8A75_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N8A75_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N8A75_00905	COG2226	methyltransferase
N8A75_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
N8A75_00920	COG0489	protein tyrosine kinase activity
N8A75_00930	COG2194	sulfuric ester hydrolase activity
N8A75_00935	COG0726	polysaccharide deacetylase
N8A75_01020	COG0659	secondary active sulfate transmembrane transporter activity
N8A75_01025	COG0385	Bile acid
N8A75_01030	COG2819	hydrolase of the alpha beta superfamily
N8A75_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8A75_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8A75_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N8A75_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N8A75_01050	COG2207	Transcriptional regulator
N8A75_01055	COG3876	Protein conserved in bacteria
N8A75_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
N8A75_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N8A75_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8A75_01070	COG1263	PTS System
N8A75_01075	COG1737	Transcriptional regulator
N8A75_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N8A75_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8A75_01090	COG1683	Conserved Protein
N8A75_01120	COG1595	DNA-templated transcription, initiation
N8A75_01125	COG5662	AntiSigma factor
N8A75_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N8A75_01135	COG4856	YbbR-like protein
N8A75_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N8A75_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N8A75_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N8A75_01160	COG2169	Transcriptional regulator
N8A75_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N8A75_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N8A75_01175	COG3002	Belongs to the UPF0753 family
N8A75_01180	COG0288	reversible hydration of carbon dioxide
N8A75_01190	COG5609	conserved protein (DUF2294)
N8A75_01195	COG0640	Transcriptional regulator
N8A75_01200	COG2814	Major facilitator Superfamily
N8A75_01215	COG0596	Alpha beta hydrolase
N8A75_01220	COG0745	RESPONSE REGULATOR receiver
N8A75_01225	COG0642	Histidine kinase
N8A75_01235	COG0515	serine threonine protein kinase
N8A75_01250	COG1113	amino acid transport
N8A75_01265	COG2602	Beta-lactamase
N8A75_01270	COG2124	cytochrome p450
N8A75_01280	COG0531	amino acid
N8A75_01285	COG0584	glycerophosphoryl diester phosphodiesterase
N8A75_01290	COG2271	Major facilitator Superfamily
N8A75_01300	COG0456	acetyltransferase
N8A75_01300	COG1846	Transcriptional regulator
N8A75_01305	COG2271	Major facilitator Superfamily
N8A75_01310	COG0697	spore germination
N8A75_01315	COG1917	Cupin 2, conserved barrel domain protein
N8A75_01315	COG2207	Transcriptional regulator
N8A75_01340	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
N8A75_01345	COG3591	Belongs to the peptidase S1B family
N8A75_01355	COG0596	Alpha beta hydrolase
N8A75_01360	COG1183	phosphatidylcholine synthase activity
N8A75_01365	COG0586	Pfam SNARE associated Golgi protein
N8A75_01370	COG0688	phosphatidylethanolamine metabolic process
N8A75_01380	COG2312	Erythromycin esterase
N8A75_01385	COG2207	Transcriptional regulator
N8A75_01390	COG1054	Belongs to the UPF0176 family
N8A75_01395	COG1301	dicarboxylic acid transport
N8A75_01400	COG1263	PTS System
N8A75_01400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8A75_01400	COG2190	(PTS) system
N8A75_01405	COG0363	glucosamine-6-phosphate deaminase activity
N8A75_01410	COG2188	Transcriptional regulator
N8A75_01420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N8A75_01425	COG0833	amino acid
N8A75_01430	COG2040	homocysteine
N8A75_01435	COG1115	amino acid carrier protein
N8A75_01440	COG2066	Belongs to the glutaminase family
N8A75_01445	COG4191	Histidine kinase
N8A75_01450	COG0784	Response regulator, receiver
N8A75_01455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N8A75_01460	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_01465	COG2271	Major facilitator Superfamily
N8A75_01470	COG4948	Mandelate Racemase Muconate Lactonizing
N8A75_01475	COG2186	Transcriptional regulator
N8A75_01480	COG2721	sulfolactate sulfo-lyase activity
N8A75_01485	COG3173	Aminoglycoside phosphotransferase
N8A75_01495	COG0697	spore germination
N8A75_01500	COG0745	RESPONSE REGULATOR receiver
N8A75_01505	COG2205	protein histidine kinase activity
N8A75_01510	COG1131	(ABC) transporter
N8A75_01530	COG3773	Cell wall hydrolase
N8A75_01535	COG2304	oxidoreductase activity
N8A75_01545	COG3540	Alkaline phosphatase
N8A75_01550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N8A75_01555	COG0805	protein transport
N8A75_01560	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
N8A75_01565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N8A75_01570	COG0477	Major facilitator Superfamily
N8A75_01575	COG1309	transcriptional regulator
N8A75_01580	COG0252	asparaginase activity
N8A75_01585	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N8A75_01590	COG1714	RDD family
N8A75_01595	COG1405	negative regulation of cell septum assembly
N8A75_01595	COG3012	SEC-C Motif Domain Protein
N8A75_01600	COG3290	protein histidine kinase activity
N8A75_01605	COG3279	Response regulator of the LytR AlgR family
N8A75_01610	COG4555	ABC transporter
N8A75_01615	COG1668	transmembrane transport
N8A75_01620	COG0667	Aldo Keto reductase
N8A75_01635	COG1595	DNA-templated transcription, initiation
N8A75_01640	COG1595	DNA-templated transcription, initiation
N8A75_01645	COG1876	peptidase activity
N8A75_01655	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_01660	COG0366	Alpha amylase catalytic
N8A75_01665	COG0803	Belongs to the bacterial solute-binding protein 9 family
N8A75_01670	COG1121	(ABC) transporter
N8A75_01675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N8A75_01680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8A75_01685	COG2310	stress, protein
N8A75_01690	COG2310	stress, protein
N8A75_01695	COG2310	stress, protein
N8A75_01700	COG0861	Integral membrane protein TerC family
N8A75_01710	COG3853	Toxic anion resistance protein (TelA)
N8A75_01715	COG0477	Major facilitator Superfamily
N8A75_01720	COG2814	Major facilitator Superfamily
N8A75_01725	COG0640	Transcriptional regulator
N8A75_01730	COG0517	IMP dehydrogenase activity
N8A75_01730	COG4175	Glycine betaine
N8A75_01735	COG4176	ABC-type proline glycine betaine transport system permease component
N8A75_01740	COG2113	Glycine betaine
N8A75_01745	COG1473	amidohydrolase
N8A75_01750	COG1288	antiporter activity
N8A75_01760	COG0366	Alpha amylase catalytic
N8A75_01765	COG0039	L-malate dehydrogenase activity
N8A75_01770	COG1620	l-lactate permease
N8A75_01775	COG2814	Major facilitator Superfamily
N8A75_01780	COG1846	Transcriptional regulator
N8A75_01785	COG1280	lysine exporter protein (LysE YggA)
N8A75_01795	COG1113	amino acid transport
N8A75_01800	COG3665	Urea carboxylase-associated protein
N8A75_01805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N8A75_01810	COG1660	Displays ATPase and GTPase activities
N8A75_01815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N8A75_01820	COG2226	methyltransferase
N8A75_01825	COG0583	DNA-binding transcription factor activity
N8A75_01830	COG3458	cephalosporin-C deacetylase activity
N8A75_01835	COG3541	Predicted nucleotidyltransferase
N8A75_01840	COG0506	proline dehydrogenase activity
N8A75_01845	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_01850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8A75_01855	COG2508	Transcriptional regulator
N8A75_01860	COG3689	TIGRFAM TIGR03943 family protein
N8A75_01865	COG0701	Predicted permease
N8A75_01870	COG2267	carboxylic ester hydrolase activity
N8A75_01875	COG0492	ferredoxin-NADP+ reductase activity
N8A75_01880	COG1587	Uroporphyrinogen-III synthase
N8A75_01880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N8A75_01885	COG2146	nitrite reductase [NAD(P)H] activity
N8A75_01890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N8A75_01895	COG0243	molybdopterin cofactor binding
N8A75_01900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N8A75_01905	COG2223	nitrite transmembrane transporter activity
N8A75_01910	COG1469	GTP cyclohydrolase I activity
N8A75_01915	COG1376	ErfK ybiS ycfS ynhG family protein
N8A75_01925	COG0523	cobalamin synthesis protein
N8A75_01930	COG0765	amino acid transport
N8A75_01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8A75_01955	COG1846	Transcriptional regulator
N8A75_01965	COG3842	ATPase activity
N8A75_01970	COG2723	6-phospho-beta-galactosidase activity
N8A75_01980	COG3209	COG3209 Rhs family protein
N8A75_01985	COG0840	transmembrane signaling receptor activity
N8A75_01985	COG3290	protein histidine kinase activity
N8A75_01990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N8A75_01995	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
N8A75_02000	COG1733	regulation of RNA biosynthetic process
N8A75_02005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8A75_02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8A75_02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8A75_02035	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N8A75_02040	COG2814	Major facilitator Superfamily
N8A75_02050	COG0697	spore germination
N8A75_02055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8A75_02065	COG2364	Membrane
N8A75_02070	COG1126	abc transporter atp-binding protein
N8A75_02075	COG0765	amino acid transport
N8A75_02080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8A75_02085	COG0583	DNA-binding transcription factor activity
N8A75_02090	COG0163	prenyltransferase activity
N8A75_02095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N8A75_02110	COG0596	Alpha beta hydrolase
N8A75_02115	COG3104	oligopeptide transport
N8A75_02120	COG5434	Belongs to the glycosyl hydrolase 28 family
N8A75_02130	COG0697	spore germination
N8A75_02140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N8A75_02145	COG1136	(ABC) transporter
N8A75_02150	COG0577	efflux transmembrane transporter activity
N8A75_02155	COG0745	RESPONSE REGULATOR receiver
N8A75_02160	COG3850	Histidine kinase
N8A75_02160	COG5002	protein histidine kinase activity
N8A75_02165	COG0457	Tetratricopeptide repeat
N8A75_02185	COG0527	aspartate kinase activity
N8A75_02190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8A75_02195	COG4605	iron ion homeostasis
N8A75_02200	COG4604	ABC transporter, ATP-binding protein
N8A75_02205	COG4607	ABC-type enterochelin transport system periplasmic component
N8A75_02215	COG2814	Major facilitator Superfamily
N8A75_02220	COG1309	transcriptional regulator
N8A75_02225	COG0778	Nitroreductase
N8A75_02230	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N8A75_02235	COG0640	Transcriptional regulator
N8A75_02240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8A75_02245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N8A75_02250	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_02255	COG4975	Glucose uptake
N8A75_02260	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_02265	COG4549	nuclear export factor GLE1
N8A75_02270	COG1276	copper resistance
N8A75_02270	COG2372	response to copper ion
N8A75_02275	COG1349	DNA-binding transcription factor activity
N8A75_02285	COG2213	PTS system mannitol-specific
N8A75_02290	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8A75_02295	COG0246	Mannitol dehydrogenase
N8A75_02300	COG0473	3-isopropylmalate dehydrogenase activity
N8A75_02305	COG0681	Belongs to the peptidase S26 family
N8A75_02315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N8A75_02325	COG0561	phosphatase activity
N8A75_02330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
N8A75_02335	COG1914	H( )-stimulated, divalent metal cation uptake system
N8A75_02340	COG4336	lyase activity
N8A75_02345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
N8A75_02350	COG1984	allophanate hydrolase subunit 2
N8A75_02355	COG1414	Transcriptional regulator
N8A75_02360	COG2755	lipolytic protein G-D-S-L family
N8A75_02370	COG2329	Antibiotic biosynthesis monooxygenase
N8A75_02375	COG0768	penicillin binding
N8A75_02380	COG4989	oxidoreductase activity
N8A75_02385	COG3711	transcriptional antiterminator
N8A75_02390	COG0318	PFAM AMP-dependent synthetase and ligase
N8A75_02395	COG2226	methyltransferase
N8A75_02400	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_02405	COG1917	Cupin 2, conserved barrel domain protein
N8A75_02410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8A75_02415	COG3871	stress protein (general stress protein 26)
N8A75_02425	COG2814	Major facilitator Superfamily
N8A75_02430	COG1522	sequence-specific DNA binding
N8A75_02435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N8A75_02435	COG0551	DNA topoisomerase type I activity
N8A75_02440	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
N8A75_02445	COG3706	GGDEF domain
N8A75_02450	COG5298	Protein conserved in bacteria
N8A75_02455	COG1215	transferase activity, transferring glycosyl groups
N8A75_02465	COG0531	amino acid
N8A75_02470	COG0494	nUDIX hydrolase
N8A75_02475	COG0028	Belongs to the TPP enzyme family
N8A75_02500	COG1914	H( )-stimulated, divalent metal cation uptake system
N8A75_02505	COG2261	transglycosylase associated protein
N8A75_02510	COG4876	unkown
N8A75_02515	COG2217	Heavy metal translocating P-type atpase
N8A75_02520	COG3729	General stress protein
N8A75_02525	COG0662	Cupin 2, conserved barrel domain protein
N8A75_02530	COG2329	Antibiotic biosynthesis monooxygenase
N8A75_02535	COG3546	catalase activity
N8A75_02540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N8A75_02545	COG3290	protein histidine kinase activity
N8A75_02550	COG4565	transcriptional regulatory protein
N8A75_02555	COG1301	dicarboxylic acid transport
N8A75_02560	COG0628	permease
N8A75_02565	COG1131	(ABC) transporter
N8A75_02570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N8A75_02580	COG1960	acyl-CoA dehydrogenase activity
N8A75_02595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N8A75_02600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8A75_02605	COG1181	Belongs to the D-alanine--D-alanine ligase family
N8A75_02610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N8A75_02615	COG0513	Belongs to the DEAD box helicase family
N8A75_02620	COG3402	PFAM membrane-flanked domain
N8A75_02625	COG3428	Bacterial PH domain
N8A75_02630	COG0705	Rhomboid family
N8A75_02635	COG0736	holo-[acyl-carrier-protein] synthase activity
N8A75_02640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N8A75_02645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N8A75_02650	COG0864	Transcriptional regulator
N8A75_02655	COG2337	Toxic component of a toxin-antitoxin (TA) module
N8A75_02660	COG1366	Belongs to the anti-sigma-factor antagonist family
N8A75_02665	COG1366	Belongs to the anti-sigma-factor antagonist family
N8A75_02670	COG2172	sigma factor antagonist activity
N8A75_02675	COG2208	phosphoserine phosphatase activity
N8A75_02680	COG1366	Belongs to the anti-sigma-factor antagonist family
N8A75_02685	COG2172	sigma factor antagonist activity
N8A75_02690	COG1191	sigma factor activity
N8A75_02695	COG2208	phosphoserine phosphatase activity
N8A75_02700	COG2183	response to ionizing radiation
N8A75_02710	COG3091	SprT-like family
N8A75_02755	COG0583	DNA-binding transcription factor activity
N8A75_02760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8A75_02770	COG5444	nuclease activity
N8A75_02780	COG1476	TRANSCRIPTIONal
N8A75_02805	COG0693	protein deglycase activity
N8A75_02810	COG1278	Cold shock
N8A75_02815	COG1329	Transcriptional regulator
N8A75_02820	COG0697	spore germination
N8A75_02825	COG2207	Transcriptional regulator
N8A75_02825	COG1917	Cupin 2, conserved barrel domain protein
N8A75_02830	COG0697	spore germination
N8A75_02835	COG3708	Transcriptional regulator
N8A75_02835	COG2207	Transcriptional regulator
N8A75_02840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8A75_02845	COG0477	Major facilitator Superfamily
N8A75_02855	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
N8A75_02865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8A75_02870	COG1309	transcriptional regulator
N8A75_02875	COG0697	spore germination
N8A75_02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8A75_02885	COG2030	dehydratase
N8A75_02890	COG3545	Serine hydrolase
N8A75_02895	COG1733	regulation of RNA biosynthetic process
N8A75_02900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N8A75_02905	COG0640	Transcriptional regulator
N8A75_02910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N8A75_02920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8A75_02925	COG0697	spore germination
N8A75_02930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8A75_02935	COG0076	glutamate decarboxylase activity
N8A75_02940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N8A75_02945	COG0640	Transcriptional regulator
N8A75_02950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N8A75_02965	COG4585	Histidine kinase
N8A75_02970	COG2197	response regulator
N8A75_02975	COG2409	Drug exporters of the RND superfamily
N8A75_02980	COG0596	Alpha beta hydrolase
N8A75_02985	COG1811	Na channel or pump
N8A75_02990	COG4978	Transcriptional regulator
N8A75_02990	COG0789	Transcriptional regulator
N8A75_02995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N8A75_03000	COG0778	Nitroreductase
N8A75_03005	COG0346	lactoylglutathione lyase activity
N8A75_03010	COG2259	Doxx family
N8A75_03015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8A75_03040	COG2323	membrane
N8A75_03045	COG0071	Belongs to the small heat shock protein (HSP20) family
N8A75_03060	COG1309	transcriptional regulator
N8A75_03070	COG0456	acetyltransferase
N8A75_03075	COG0488	(ABC) transporter
N8A75_03080	COG1113	amino acid transport
N8A75_03085	COG2318	DinB family
N8A75_03090	COG1846	Transcriptional regulator
N8A75_03095	COG2409	Drug exporters of the RND superfamily
N8A75_03095	COG1033	growth of symbiont in host cell
N8A75_03100	COG0778	Nitroreductase
N8A75_03105	COG1846	Transcriptional regulator
N8A75_03110	COG2814	Major facilitator Superfamily
N8A75_03115	COG0730	response to heat
N8A75_03120	COG1802	Transcriptional regulator
N8A75_03125	COG1388	LysM domain
N8A75_03125	COG3858	chitin binding
N8A75_03130	COG1819	glycosyl
N8A75_03140	COG1785	Belongs to the alkaline phosphatase family
N8A75_03145	COG5646	InterPro IPR014922
N8A75_03155	COG0454	-acetyltransferase
N8A75_03160	COG1078	dGTPase activity
N8A75_03165	COG1388	LysM domain
N8A75_03170	COG2814	Major facilitator Superfamily
N8A75_03175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N8A75_03180	COG1447	Phosphotransferase system cellobiose-specific component IIA
N8A75_03185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N8A75_03190	COG2723	6-phospho-beta-galactosidase activity
N8A75_03195	COG2188	Transcriptional regulator
N8A75_03200	COG1940	carbohydrate kinase activity
N8A75_03205	COG1482	cell wall glycoprotein biosynthetic process
N8A75_03210	COG4124	Belongs to the glycosyl hydrolase 26 family
N8A75_03255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N8A75_03260	COG0802	atpase or kinase
N8A75_03265	COG1214	PFAM Peptidase M22, glycoprotease
N8A75_03270	COG0456	acetyltransferase
N8A75_03275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N8A75_03280	COG0488	(ABC) transporter
N8A75_03285	COG0315	cyclic pyranopterin monophosphate synthase activity
N8A75_03290	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
N8A75_03295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N8A75_03300	COG0805	protein transport
N8A75_03310	COG1266	CAAX protease self-immunity
N8A75_03320	COG0459	protein refolding
N8A75_03325	COG1073	alpha beta
N8A75_03330	COG0457	Tetratricopeptide repeat
N8A75_03335	COG1063	alcohol dehydrogenase
N8A75_03340	COG2211	Major facilitator Superfamily
N8A75_03345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8A75_03350	COG1842	Phage shock protein A
N8A75_03355	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N8A75_03360	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
N8A75_03365	COG4260	virion core protein, lumpy skin disease virus
N8A75_03375	COG2814	Major facilitator Superfamily
N8A75_03380	COG1063	alcohol dehydrogenase
N8A75_03385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N8A75_03390	COG0823	Involved in the tonB-independent uptake of proteins
N8A75_03405	COG2267	carboxylic ester hydrolase activity
N8A75_03415	COG2132	Multicopper oxidase
N8A75_03420	COG1113	amino acid transport
N8A75_03430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N8A75_03435	COG0714	Associated with various cellular activities
N8A75_03440	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
N8A75_03445	COG1305	Transglutaminase-like
N8A75_03455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N8A75_03455	COG0519	Catalyzes the synthesis of GMP from XMP
N8A75_03470	COG2252	PERMEase
N8A75_03475	COG3064	Membrane
N8A75_03485	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
N8A75_03495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N8A75_03500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N8A75_03505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N8A75_03510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N8A75_03515	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N8A75_03520	COG0047	phosphoribosylformylglycinamidine synthase activity
N8A75_03525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N8A75_03530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N8A75_03535	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N8A75_03540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N8A75_03545	COG0138	bifunctional purine biosynthesis protein purh
N8A75_03550	COG0151	Belongs to the GarS family
N8A75_03555	COG1522	sequence-specific DNA binding
N8A75_03560	COG0531	amino acid
N8A75_03570	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N8A75_03575	COG1470	cell adhesion involved in biofilm formation
N8A75_03580	COG4496	protein, YerC YecD
N8A75_03590	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
N8A75_03595	COG0210	DNA helicase
N8A75_03600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N8A75_03605	COG4851	CamS sex pheromone cAM373 precursor
N8A75_03610	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N8A75_03615	COG1285	pathogenesis
N8A75_03620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8A75_03625	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N8A75_03630	COG0154	amidase activity
N8A75_03635	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N8A75_03645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N8A75_03650	COG1597	lipid kinase activity
N8A75_03655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N8A75_03675	COG1401	restriction endodeoxyribonuclease activity
N8A75_03745	COG5444	nuclease activity
N8A75_03755	COG0457	Tetratricopeptide repeat
N8A75_03765	COG0217	transcriptional regulatory protein
N8A75_03775	COG1309	transcriptional regulator
N8A75_03780	COG3631	Ketosteroid isomerase-related protein
N8A75_03800	COG3546	catalase activity
N8A75_03805	COG0454	-acetyltransferase
N8A75_03815	COG5578	integral membrane protein
N8A75_03820	COG2972	Histidine kinase
N8A75_03825	COG4753	response regulator
N8A75_03825	COG2207	Transcriptional regulator
N8A75_03830	COG1653	transport
N8A75_03835	COG1175	transmembrane transport
N8A75_03840	COG0395	ABC-type sugar transport system, permease component
N8A75_03845	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N8A75_03850	COG2207	Transcriptional regulator
N8A75_03855	COG2755	lipolytic protein G-D-S-L family
N8A75_03865	COG5578	integral membrane protein
N8A75_03870	COG3401	FG-GAP repeat protein
N8A75_03875	COG3401	FG-GAP repeat protein
N8A75_03880	COG2755	lipolytic protein G-D-S-L family
N8A75_03895	COG1653	transport
N8A75_03900	COG4209	transmembrane transport
N8A75_03905	COG0395	ABC-type sugar transport system, permease component
N8A75_03910	COG1486	melibiose metabolic process
N8A75_03915	COG2323	membrane
N8A75_03920	COG2329	Antibiotic biosynthesis monooxygenase
N8A75_03925	COG0346	lactoylglutathione lyase activity
N8A75_03940	COG5583	Uncharacterized small protein (DUF2292)
N8A75_03945	COG0670	Belongs to the BI1 family
N8A75_03960	COG3328	transposase activity
N8A75_03970	COG2124	cytochrome p450
N8A75_03970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N8A75_03975	COG1368	sulfuric ester hydrolase activity
N8A75_03980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N8A75_03985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N8A75_03990	COG1442	glycosyl transferase family 8
N8A75_03995	COG1216	Glycosyl transferase, family 2
N8A75_04000	COG1442	glycosyl transferase family 8
N8A75_04005	COG2223	nitrite transmembrane transporter activity
N8A75_04010	COG1011	Hydrolase
N8A75_04015	COG0531	amino acid
N8A75_04020	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_04025	COG0840	transmembrane signaling receptor activity
N8A75_04030	COG0488	(ABC) transporter
N8A75_04040	COG0789	Transcriptional regulator
N8A75_04045	COG2814	Major facilitator Superfamily
N8A75_04060	COG0488	(ABC) transporter
N8A75_04065	COG0513	Belongs to the DEAD box helicase family
N8A75_04070	COG0456	acetyltransferase
N8A75_04075	COG2130	NADP-dependent
N8A75_04080	COG2211	Major facilitator Superfamily
N8A75_04085	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N8A75_04090	COG1120	ATPase activity
N8A75_04095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8A75_04100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8A75_04105	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
N8A75_04120	COG3866	Pectate lyase
N8A75_04125	COG0471	metal ion transport
N8A75_04130	COG3290	protein histidine kinase activity
N8A75_04135	COG4565	transcriptional regulatory protein
N8A75_04140	COG3181	Tripartite tricarboxylate transporter family receptor
N8A75_04150	COG2851	Citrate transporter
N8A75_04155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8A75_04160	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
N8A75_04165	COG1254	Belongs to the acylphosphatase family
N8A75_04170	COG2258	MOSC domain
N8A75_04190	COG0024	Methionine aminopeptidase
N8A75_04195	COG1263	PTS System
N8A75_04195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8A75_04200	COG1368	sulfuric ester hydrolase activity
N8A75_04215	COG1115	amino acid carrier protein
N8A75_04235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8A75_04235	COG1263	PTS System
N8A75_04240	COG0366	Alpha amylase catalytic
N8A75_04245	COG2188	Transcriptional regulator
N8A75_04250	COG0778	Nitroreductase
N8A75_04255	COG0737	Belongs to the 5'-nucleotidase family
N8A75_04260	COG0693	protein deglycase activity
N8A75_04265	COG2814	Major facilitator Superfamily
N8A75_04270	COG4840	Belongs to the UPF0435 family
N8A75_04275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N8A75_04280	COG4980	gas vesicle protein
N8A75_04285	COG1295	ribonuclease BN
N8A75_04290	COG0477	Major facilitator Superfamily
N8A75_04295	COG0387	Pfam Sodium calcium exchanger
N8A75_04305	COG0668	transmembrane transport
N8A75_04310	COG0535	radical SAM domain protein
N8A75_04320	COG0726	polysaccharide deacetylase
N8A75_04325	COG2084	Dehydrogenase
N8A75_04330	COG0598	Magnesium transport protein CorA
N8A75_04335	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N8A75_04340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N8A75_04350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N8A75_04355	COG4637	Psort location Cytoplasmic, score
N8A75_04365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N8A75_04370	COG0022	dehydrogenase e1 component
N8A75_04375	COG0508	dehydrogenase complex catalyzes the overall conversion of
N8A75_04380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N8A75_04385	COG3284	Transcriptional regulator
N8A75_04395	COG1742	UPF0060 membrane protein
N8A75_04420	COG4842	Belongs to the WXG100 family
N8A75_04425	COG1486	melibiose metabolic process
N8A75_04430	COG1737	Transcriptional regulator
N8A75_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8A75_04435	COG1263	PTS System
N8A75_04440	COG1132	(ABC) transporter
N8A75_04445	COG1132	(ABC) transporter
N8A75_04450	COG2259	Doxx family
N8A75_04455	COG2514	catechol 2,3-dioxygenase activity
N8A75_04460	COG1917	Cupin 2, conserved barrel domain protein
N8A75_04460	COG4977	sequence-specific DNA binding
N8A75_04465	COG2814	Major facilitator Superfamily
N8A75_04470	COG1082	Xylose isomerase domain protein TIM barrel
N8A75_04475	COG0673	inositol 2-dehydrogenase activity
N8A75_04480	COG4585	Histidine kinase
N8A75_04485	COG2197	response regulator
N8A75_04490	COG1131	(ABC) transporter
N8A75_04495	COG0842	Transport permease protein
N8A75_04495	COG1511	domain protein
N8A75_04500	COG0842	Transport permease protein
N8A75_04505	COG1695	Transcriptional regulator
N8A75_04510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N8A75_04515	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
N8A75_04520	COG1309	transcriptional regulator
N8A75_04525	COG2814	Major facilitator Superfamily
N8A75_04530	COG2318	DinB family
N8A75_04535	COG2814	Major facilitator Superfamily
N8A75_04540	COG1846	Transcriptional regulator
N8A75_04545	COG0392	lysyltransferase activity
N8A75_04545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N8A75_04550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N8A75_04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8A75_04560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8A75_04565	COG0384	phenazine biosynthesis protein PhzF
N8A75_04570	COG0778	Nitroreductase
N8A75_04585	COG1090	epimerase
N8A75_04590	COG2137	regulation of response to DNA damage stimulus
N8A75_04600	COG2814	Major facilitator Superfamily
N8A75_04615	COG3103	Sh3 type 3 domain protein
N8A75_04620	COG5658	integral membrane protein
N8A75_04625	COG0596	Alpha beta hydrolase
N8A75_04630	COG0463	Glycosyl transferase, family 2
N8A75_04635	COG4485	Bacterial membrane protein, YfhO
N8A75_04640	COG1988	membrane-bound metal-dependent
N8A75_04645	COG1194	a g-specific adenine glycosylase
N8A75_04655	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_04670	COG3557	Belongs to the UPF0374 family
N8A75_04675	COG1132	(ABC) transporter
N8A75_04680	COG4129	membrane
N8A75_04685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N8A75_04690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N8A75_04695	COG0735	belongs to the Fur family
N8A75_04805	COG4326	sporulation control protein
N8A75_04815	COG5577	PFAM Coat F domain
N8A75_04820	COG3340	Belongs to the peptidase S51 family
N8A75_04825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N8A75_04835	COG0753	catalase activity
N8A75_04840	COG1116	anion transmembrane transporter activity
N8A75_04845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N8A75_04850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N8A75_04855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8A75_04865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N8A75_04875	COG1476	TRANSCRIPTIONal
N8A75_04885	COG3382	B3 4 domain protein
N8A75_04890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N8A75_04900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N8A75_04905	COG0789	Transcriptional regulator
N8A75_04910	COG1664	Polymer-forming cytoskeletal
N8A75_04915	COG1664	Polymer-forming cytoskeletal
N8A75_04920	COG2766	serine protein kinase
N8A75_04925	COG2718	Belongs to the UPF0229 family
N8A75_04930	COG1846	Transcriptional regulator
N8A75_04935	COG1566	PFAM secretion protein HlyD family protein
N8A75_04940	COG2814	Major facilitator Superfamily
N8A75_04945	COG0655	NAD(P)H dehydrogenase (quinone) activity
N8A75_04965	COG1725	Transcriptional regulator
N8A75_04970	COG1131	(ABC) transporter
N8A75_04975	COG1131	(ABC) transporter
N8A75_04980	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N8A75_04985	COG1278	Cold shock
N8A75_04990	COG1464	Belongs to the NlpA lipoprotein family
N8A75_04995	COG3706	GGDEF domain
N8A75_05000	COG1823	symporter activity
N8A75_05020	COG5577	PFAM Coat F domain
N8A75_05025	COG4085	toxin activity
N8A75_05025	COG1525	nuclease
N8A75_05025	COG0737	Belongs to the 5'-nucleotidase family
N8A75_05030	COG3764	Sortase (surface protein transpeptidase)
N8A75_05035	COG0564	pseudouridine synthase activity
N8A75_05045	COG0517	IMP dehydrogenase activity
N8A75_05050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N8A75_05055	COG3153	acetyltransferase
N8A75_05055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N8A75_05060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N8A75_05065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
N8A75_05070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N8A75_05075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N8A75_05080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N8A75_05085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N8A75_05090	COG2203	Gaf domain
N8A75_05090	COG4585	Histidine kinase
N8A75_05095	COG2197	response regulator
N8A75_05100	COG0431	NADPH-dependent FMN reductase
N8A75_05115	COG1388	LysM domain
N8A75_05115	COG0791	NLP P60 protein
N8A75_05120	COG1959	2 iron, 2 sulfur cluster binding
N8A75_05125	COG0668	transmembrane transport
N8A75_05130	COG2719	SpoVR family
N8A75_05135	COG1785	Belongs to the alkaline phosphatase family
N8A75_05140	COG0791	NLP P60 protein
N8A75_05140	COG1388	LysM domain
N8A75_05145	COG0583	DNA-binding transcription factor activity
N8A75_05150	COG0372	Belongs to the citrate synthase family
N8A75_05155	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_05160	COG0531	amino acid
N8A75_05165	COG0733	neurotransmitter:sodium symporter activity
N8A75_05170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8A75_05175	COG0456	acetyltransferase
N8A75_05190	COG1595	DNA-templated transcription, initiation
N8A75_05195	COG0667	Aldo Keto reductase
N8A75_05200	COG0204	Acyl-transferase
N8A75_05205	COG1253	flavin adenine dinucleotide binding
N8A75_05210	COG0789	Transcriptional regulator
N8A75_05215	COG0436	Aminotransferase
N8A75_05220	COG1253	flavin adenine dinucleotide binding
N8A75_05225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N8A75_05230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N8A75_05235	COG0584	glycerophosphoryl diester phosphodiesterase
N8A75_05245	COG0668	transmembrane transport
N8A75_05250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N8A75_05255	COG0726	polysaccharide deacetylase
N8A75_05260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N8A75_05265	COG1757	Na H antiporter
N8A75_05270	COG0589	response to stress
N8A75_05280	COG1132	(ABC) transporter
N8A75_05285	COG1132	(ABC) transporter
N8A75_05290	COG0702	epimerase
N8A75_05310	COG0189	ligase activity
N8A75_05315	COG0189	ligase activity
N8A75_05320	COG4399	Belongs to the UPF0754 family
N8A75_05325	COG3679	Belongs to the UPF0342 family
N8A75_05330	COG4335	DNA alkylation repair
N8A75_05335	COG0561	phosphatase activity
N8A75_05340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N8A75_05345	COG0475	glutathione-regulated potassium exporter activity
N8A75_05350	COG0490	domain, Protein
N8A75_05360	COG1024	Enoyl-CoA hydratase
N8A75_05370	COG4152	abc transporter atp-binding protein
N8A75_05375	COG1668	transmembrane transport
N8A75_05380	COG0420	3'-5' exonuclease activity
N8A75_05385	COG4717	serine-type aminopeptidase activity
N8A75_05390	COG3481	metal-dependent phosphohydrolase, HD sub domain
N8A75_05400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N8A75_05430	COG1846	Transcriptional regulator
N8A75_05435	COG4980	gas vesicle protein
N8A75_05450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N8A75_05455	COG0537	adenosine 5'-monophosphoramidase activity
N8A75_05460	COG1131	(ABC) transporter
N8A75_05465	COG4473	ABC transporter
N8A75_05475	COG1473	amidohydrolase
N8A75_05480	COG3069	C4-dicarboxylate transmembrane transporter activity
N8A75_05490	COG2329	Antibiotic biosynthesis monooxygenase
N8A75_05495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N8A75_05500	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N8A75_05505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N8A75_05510	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
N8A75_05515	COG1309	transcriptional regulator
N8A75_05520	COG1511	domain protein
N8A75_05525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8A75_05530	COG4377	Putative membrane peptidase family (DUF2324)
N8A75_05540	COG1363	Peptidase, m42
N8A75_05545	COG4405	Protein conserved in bacteria
N8A75_05550	COG1301	dicarboxylic acid transport
N8A75_05560	COG1234	tRNA 3'-trailer cleavage
N8A75_05565	COG0095	Lipoate-protein ligase
N8A75_05570	COG0702	epimerase
N8A75_05575	COG0318	PFAM AMP-dependent synthetase and ligase
N8A75_05585	COG0501	Belongs to the peptidase M48B family
N8A75_05595	COG0456	acetyltransferase
N8A75_05600	COG0604	alcohol dehydrogenase
N8A75_05605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
N8A75_05610	COG0406	alpha-ribazole phosphatase activity
N8A75_05615	COG0183	Belongs to the thiolase family
N8A75_05620	COG0318	PFAM AMP-dependent synthetase and ligase
N8A75_05625	COG1268	BioY protein
N8A75_05630	COG0840	transmembrane signaling receptor activity
N8A75_05635	COG0723	plastoquinol--plastocyanin reductase activity
N8A75_05635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N8A75_05640	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_05650	COG4903	ComK protein
N8A75_05655	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_05665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8A75_05680	COG0398	Pfam SNARE associated Golgi protein
N8A75_05685	COG0681	Belongs to the peptidase S26 family
N8A75_05690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N8A75_05695	COG1846	Transcriptional regulator
N8A75_05700	COG0738	Major facilitator superfamily
N8A75_05705	COG0673	inositol 2-dehydrogenase activity
N8A75_05710	COG0561	phosphatase activity
N8A75_05715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N8A75_05720	COG1609	Transcriptional regulator
N8A75_05725	COG3180	Ammonia monooxygenase
N8A75_05730	COG0477	Major facilitator Superfamily
N8A75_05730	COG2814	Major facilitator Superfamily
N8A75_05735	COG4533	DNA binding
N8A75_05745	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
N8A75_05750	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
N8A75_05755	COG1074	ATP-dependent DNA helicase activity
N8A75_05760	COG0420	3'-5' exonuclease activity
N8A75_05765	COG0419	ATPase involved in DNA repair
N8A75_05770	COG1403	HNH endonuclease
N8A75_05810	COG5337	Spore coat protein CotH
N8A75_05815	COG0179	Fumarylacetoacetate (FAA) hydrolase
N8A75_05825	COG1404	Belongs to the peptidase S8 family
N8A75_05835	COG0367	asparagine synthase
N8A75_05845	COG0534	Mate efflux family protein
N8A75_05850	COG2207	Transcriptional regulator
N8A75_05850	COG1917	Cupin 2, conserved barrel domain protein
N8A75_05855	COG1609	Transcriptional regulator
N8A75_05860	COG0673	inositol 2-dehydrogenase activity
N8A75_05865	COG2318	DinB family
N8A75_05875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8A75_05880	COG1357	PFAM Pentapeptide repeats (8 copies)
N8A75_05885	COG2267	carboxylic ester hydrolase activity
N8A75_05890	COG0529	Catalyzes the synthesis of activated sulfate
N8A75_05895	COG2046	Belongs to the sulfate adenylyltransferase family
N8A75_05900	COG0175	sulfate reduction
N8A75_05905	COG2045	Belongs to the ComB family
N8A75_05910	COG1809	phosphosulfolactate synthase activity
N8A75_05915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N8A75_05920	COG4948	Mandelate Racemase Muconate Lactonizing
N8A75_05925	COG2814	Major facilitator Superfamily
N8A75_05930	COG0454	-acetyltransferase
N8A75_05935	COG2153	protein acetylation
N8A75_05940	COG0646	methionine synthase
N8A75_05940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N8A75_05945	COG1666	GTP binding
N8A75_05970	COG1695	Transcriptional regulator
N8A75_05985	COG3227	Zinc metalloprotease (Elastase)
N8A75_05990	COG1307	EDD domain protein, DegV family
N8A75_05995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N8A75_06015	COG0561	phosphatase activity
N8A75_06020	COG1073	alpha beta
N8A75_06025	COG2151	metal-sulfur cluster biosynthetic enzyme
N8A75_06035	COG0277	FAD linked oxidase domain protein
N8A75_06040	COG2271	Major facilitator Superfamily
N8A75_06045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N8A75_06050	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N8A75_06060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N8A75_06065	COG0505	Belongs to the CarA family
N8A75_06070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N8A75_06075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N8A75_06090	COG2267	carboxylic ester hydrolase activity
N8A75_06100	COG1744	ABC transporter substrate-binding protein PnrA-like
N8A75_06115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8A75_06120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N8A75_06125	COG5504	Zn-dependent protease
N8A75_06130	COG0444	Belongs to the ABC transporter superfamily
N8A75_06135	COG4608	Belongs to the ABC transporter superfamily
N8A75_06145	COG0601	transmembrane transport
N8A75_06150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N8A75_06160	COG0180	Tryptophanyl-tRNA synthetase
N8A75_06165	COG4166	transmembrane transport
N8A75_06170	COG0601	transmembrane transport
N8A75_06175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N8A75_06180	COG0444	Belongs to the ABC transporter superfamily
N8A75_06185	COG4608	Belongs to the ABC transporter superfamily
N8A75_06190	COG2814	Major facilitator Superfamily
N8A75_06195	COG0456	acetyltransferase
N8A75_06200	COG1393	Belongs to the ArsC family
N8A75_06205	COG0861	Integral membrane protein TerC family
N8A75_06215	COG4862	establishment of competence for transformation
N8A75_06225	COG4469	Competence protein
N8A75_06230	COG1164	Oligoendopeptidase f
N8A75_06240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N8A75_06245	COG2346	COG2346, Truncated hemoglobins
N8A75_06250	COG0741	lytic transglycosylase activity
N8A75_06255	COG4116	CYTH
N8A75_06265	COG2357	RelA SpoT domain protein
N8A75_06270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N8A75_06275	COG0564	pseudouridine synthase activity
N8A75_06280	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N8A75_06285	COG0569	domain protein
N8A75_06285	COG0475	glutathione-regulated potassium exporter activity
N8A75_06290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N8A75_06295	COG0352	thiamine-phosphate diphosphorylase activity
N8A75_06300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N8A75_06305	COG2104	thiamine diphosphate biosynthetic process
N8A75_06310	COG2022	thiamine diphosphate biosynthetic process
N8A75_06315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N8A75_06320	COG0351	phosphomethylpyrimidine kinase
N8A75_06325	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N8A75_06380	COG0210	DNA helicase
N8A75_06390	COG2153	protein acetylation
N8A75_06395	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N8A75_06400	COG2382	esterase
N8A75_06405	COG0626	cystathionine gamma-synthase activity
N8A75_06410	COG0626	cystathionine gamma-synthase activity
N8A75_06415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8A75_06420	COG5505	Protein of unknown function (DUF819)
N8A75_06455	COG3677	Transposase
N8A75_06470	COG5484	DNA packaging
N8A75_06475	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N8A75_06480	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_06490	COG3711	transcriptional antiterminator
N8A75_06490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8A75_06495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8A75_06495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N8A75_06495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N8A75_06500	COG1482	cell wall glycoprotein biosynthetic process
N8A75_06510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8A75_06520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N8A75_06535	COG0109	protoheme IX farnesyltransferase activity
N8A75_06545	COG0726	polysaccharide deacetylase
N8A75_06560	COG5504	Zn-dependent protease
N8A75_06565	COG2205	protein histidine kinase activity
N8A75_06575	COG3383	formate dehydrogenase (NAD+) activity
N8A75_06580	COG2427	Protein of unknown function (DUF1641)
N8A75_06590	COG1051	belongs to the nudix hydrolase family
N8A75_06600	COG2124	cytochrome p450
N8A75_06605	COG1819	glycosyl
N8A75_06615	COG1587	Uroporphyrinogen-III synthase
N8A75_06620	COG0390	transport system, permease component
N8A75_06625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N8A75_06630	COG0697	spore germination
N8A75_06635	COG4297	protein containing double-stranded beta helix domain
N8A75_06645	COG1252	NADH dehydrogenase
N8A75_06650	COG1904	glucuronate isomerase
N8A75_06655	COG2211	Major facilitator Superfamily
N8A75_06660	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N8A75_06665	COG1063	alcohol dehydrogenase
N8A75_06670	COG1312	Catalyzes the dehydration of D-mannonate
N8A75_06675	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_06680	COG2271	Major facilitator Superfamily
N8A75_06685	COG1609	Transcriptional regulator
N8A75_06690	COG0246	Mannitol dehydrogenase
N8A75_06695	COG2721	sulfolactate sulfo-lyase activity
N8A75_06700	COG0730	response to heat
N8A75_06705	COG2318	DinB family
N8A75_06710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N8A75_06715	COG0457	Tetratricopeptide repeat
N8A75_06730	COG5632	N-Acetylmuramoyl-L-alanine amidase
N8A75_06730	COG3409	Peptidoglycan-binding domain 1 protein
N8A75_06730	COG1388	LysM domain
N8A75_06740	COG4195	phage-related replication protein
N8A75_06745	COG3546	catalase activity
N8A75_06750	COG2856	Zn peptidase
N8A75_06755	COG1396	sequence-specific DNA binding
N8A75_06765	COG1522	sequence-specific DNA binding
N8A75_06770	COG1484	DNA-dependent DNA replication
N8A75_06790	COG1595	DNA-templated transcription, initiation
N8A75_06795	COG5484	DNA packaging
N8A75_06795	COG3728	DNA packaging
N8A75_06800	COG1783	phage Terminase large subunit
N8A75_06805	COG5518	Phage portal protein
N8A75_06810	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N8A75_06815	COG4653	Phage capsid family
N8A75_06865	COG5412	phage tail tape measure protein
N8A75_06865	COG3953	SLT domain
N8A75_06865	COG5412	phage tail tape measure protein
N8A75_06865	COG3953	SLT domain
N8A75_06865	COG5412	phage tail tape measure protein
N8A75_06865	COG3953	SLT domain
N8A75_06870	COG1652	LysM domain
N8A75_06875	COG4193	domain, Protein
N8A75_06885	COG3628	GPW Gp25 family protein
N8A75_06890	COG3299	homolog of phage Mu protein gp47
N8A75_06895	COG3778	Protein conserved in bacteria
N8A75_06935	COG5632	N-Acetylmuramoyl-L-alanine amidase
N8A75_06935	COG3409	Peptidoglycan-binding domain 1 protein
N8A75_06955	COG0306	phosphate transporter
N8A75_06960	COG1392	Phosphate transport regulator
N8A75_06965	COG0531	amino acid
N8A75_06970	COG0346	lactoylglutathione lyase activity
N8A75_06980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N8A75_06985	COG0463	Glycosyl transferase, family 2
N8A75_06995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N8A75_07000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N8A75_07005	COG2362	D-Aminopeptidase
N8A75_07010	COG0601	transmembrane transport
N8A75_07015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N8A75_07020	COG0444	Belongs to the ABC transporter superfamily
N8A75_07025	COG4166	transmembrane transport
N8A75_07030	COG1619	proteins homologs of microcin C7 resistance protein MccF
N8A75_07035	COG4948	Mandelate Racemase Muconate Lactonizing
N8A75_07040	COG0791	NLP P60 protein
N8A75_07045	COG4608	Belongs to the ABC transporter superfamily
N8A75_07050	COG2706	6-phosphogluconolactonase activity
N8A75_07055	COG1834	amidinotransferase
N8A75_07060	COG1607	acyl-coa hydrolase
N8A75_07065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N8A75_07065	COG1017	nitric oxide dioxygenase activity
N8A75_07075	COG2323	membrane
N8A75_07080	COG2318	DinB family
N8A75_07085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8A75_07090	COG2076	Multidrug Resistance protein
N8A75_07095	COG2076	Multidrug Resistance protein
N8A75_07100	COG0788	formyltetrahydrofolate deformylase activity
N8A75_07105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N8A75_07110	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N8A75_07115	COG1764	response to oxidative stress
N8A75_07120	COG1846	Transcriptional regulator
N8A75_07125	COG1764	response to oxidative stress
N8A75_07135	COG0590	tRNA wobble adenosine to inosine editing
N8A75_07140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N8A75_07145	COG1404	Belongs to the peptidase S8 family
N8A75_07150	COG1366	Belongs to the anti-sigma-factor antagonist family
N8A75_07155	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N8A75_07160	COG1122	ATPase activity
N8A75_07165	COG4721	ABC-type cobalt transport system, permease component
N8A75_07175	COG0745	RESPONSE REGULATOR receiver
N8A75_07180	COG5002	protein histidine kinase activity
N8A75_07180	COG3850	Histidine kinase
N8A75_07185	COG3212	peptidase
N8A75_07190	COG3212	peptidase
N8A75_07205	COG2239	Acts as a magnesium transporter
N8A75_07210	COG0789	Transcriptional regulator
N8A75_07225	COG1846	Transcriptional regulator
N8A75_07235	COG0726	polysaccharide deacetylase
N8A75_07240	COG1408	metallophosphoesterase
N8A75_07250	COG0463	Glycosyl transferase, family 2
N8A75_07255	COG1793	dna ligase
N8A75_07255	COG3285	dna ligase
N8A75_07260	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
N8A75_07265	COG3300	MHYT domain
N8A75_07265	COG5001	Diguanylate cyclase
N8A75_07270	COG0586	Pfam SNARE associated Golgi protein
N8A75_07275	COG0861	Integral membrane protein TerC family
N8A75_07280	COG1191	sigma factor activity
N8A75_07300	COG0501	Belongs to the peptidase M48B family
N8A75_07305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N8A75_07320	COG3594	Acyltransferase
N8A75_07325	COG5002	protein histidine kinase activity
N8A75_07330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N8A75_07340	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N8A75_07345	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
N8A75_07350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N8A75_07355	COG0436	Aminotransferase
N8A75_07360	COG1850	ribulose-bisphosphate carboxylase activity
N8A75_07365	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
N8A75_07370	COG0235	Class ii aldolase
N8A75_07375	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
N8A75_07380	COG3339	Conserved Protein
N8A75_07395	COG3852	Histidine kinase
N8A75_07400	COG1846	Transcriptional regulator
N8A75_07405	COG1360	Flagellar Motor Protein
N8A75_07410	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N8A75_07415	COG0542	response to heat
N8A75_07420	COG3949	Membrane
N8A75_07425	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N8A75_07430	COG0720	synthase
N8A75_07435	COG0602	queuosine metabolic process
N8A75_07440	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N8A75_07445	COG1733	regulation of RNA biosynthetic process
N8A75_07450	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_07455	COG4641	Protein conserved in bacteria
N8A75_07455	COG1388	LysM domain
N8A75_07460	COG1388	LysM domain
N8A75_07465	COG3858	chitin binding
N8A75_07475	COG4873	Protein conserved in bacteria
N8A75_07485	COG3773	Cell wall hydrolase
N8A75_07490	COG2244	polysaccharide biosynthetic process
N8A75_07495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8A75_07500	COG2217	Heavy metal translocating P-type atpase
N8A75_07510	COG0006	proline dipeptidase activity
N8A75_07515	COG1609	Transcriptional regulator
N8A75_07520	COG3711	transcriptional antiterminator
N8A75_07525	COG2190	(PTS) system
N8A75_07525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8A75_07525	COG1263	PTS System
N8A75_07530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8A75_07535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N8A75_07545	COG1533	DNA photolyase activity
N8A75_07550	COG0456	acetyltransferase
N8A75_07555	COG0840	transmembrane signaling receptor activity
N8A75_07560	COG2084	Dehydrogenase
N8A75_07565	COG2340	Cysteine-rich secretory protein family
N8A75_07570	COG0768	penicillin binding
N8A75_07575	COG4191	Histidine kinase
N8A75_07580	COG0436	Aminotransferase
N8A75_07590	COG0784	Response regulator, receiver
N8A75_07590	COG0835	chemotaxis
N8A75_07600	COG2814	Major facilitator Superfamily
N8A75_07605	COG1376	ErfK ybiS ycfS ynhG family protein
N8A75_07610	COG1408	metallophosphoesterase
N8A75_07615	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_07620	COG2200	EAL domain
N8A75_07625	COG4703	Protein of unknown function (DUF1797)
N8A75_07630	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
N8A75_07640	COG0517	IMP dehydrogenase activity
N8A75_07645	COG0583	DNA-binding transcription factor activity
N8A75_07650	COG0716	FMN binding
N8A75_07660	COG0716	FMN binding
N8A75_07665	COG2171	N-acyltransferase activity
N8A75_07670	COG1473	amidohydrolase
N8A75_07680	COG0668	transmembrane transport
N8A75_07685	COG0450	alkyl hydroperoxide reductase
N8A75_07690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8A75_07705	COG0746	molybdenum cofactor guanylyltransferase activity
N8A75_07710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N8A75_07715	COG0303	'Molybdopterin
N8A75_07720	COG1763	Mo-molybdopterin cofactor biosynthetic process
N8A75_07725	COG0314	molybdopterin synthase activity
N8A75_07730	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N8A75_07735	COG1132	(ABC) transporter
N8A75_07740	COG1132	(ABC) transporter
N8A75_07750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N8A75_07755	COG1136	(ABC) transporter
N8A75_07760	COG0577	efflux transmembrane transporter activity
N8A75_07765	COG1349	DNA-binding transcription factor activity
N8A75_07770	COG1105	Belongs to the carbohydrate kinase PfkB family
N8A75_07775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8A75_07775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N8A75_07775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N8A75_07780	COG0681	Belongs to the peptidase S26 family
N8A75_07790	COG0488	(ABC) transporter
N8A75_07795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N8A75_07800	COG2309	aminopeptidase activity
N8A75_07810	COG1077	Cell shape determining protein MreB Mrl
N8A75_07815	COG2002	toxin-antitoxin pair type II binding
N8A75_07820	COG3852	Histidine kinase
N8A75_07825	COG2105	PFAM AIG2 family protein
N8A75_07825	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
N8A75_07830	COG0569	domain protein
N8A75_07835	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N8A75_07840	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N8A75_07845	COG5503	Protein of unknown function (DUF1447)
N8A75_07850	COG0561	phosphatase activity
N8A75_07855	COG0242	peptide deformylase activity
N8A75_07865	COG0497	DNA recombination
N8A75_07870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N8A75_07875	COG0022	dehydrogenase e1 component
N8A75_07880	COG0508	dehydrogenase complex catalyzes the overall conversion of
N8A75_07885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N8A75_07890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8A75_07900	COG1982	Orn Lys Arg decarboxylase major
N8A75_07905	COG4476	Belongs to the UPF0223 family
N8A75_07910	COG4493	Belongs to the UPF0637 family
N8A75_07920	COG0483	inositol monophosphate 1-phosphatase activity
N8A75_07930	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
N8A75_07950	COG1595	DNA-templated transcription, initiation
N8A75_07970	COG1217	gtp-binding protein TYPA
N8A75_07980	COG4896	Protein conserved in bacteria
N8A75_07990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N8A75_07995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N8A75_08000	COG2066	Belongs to the glutaminase family
N8A75_08005	COG4838	Belongs to the UPF0358 family
N8A75_08010	COG0772	Belongs to the SEDS family
N8A75_08015	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N8A75_08020	COG1612	heme a metabolic process
N8A75_08025	COG0109	protoheme IX farnesyltransferase activity
N8A75_08030	COG2010	Cytochrome c
N8A75_08030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N8A75_08035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N8A75_08040	COG1845	cytochrome c oxidase, subunit III
N8A75_08045	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N8A75_08050	COG3336	cytochrome c oxidase
N8A75_08060	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
N8A75_08065	COG2340	Cysteine-rich secretory protein family
N8A75_08080	COG3679	Belongs to the UPF0342 family
N8A75_08085	COG4471	UPF0298 protein
N8A75_08090	COG0742	ribosomal rna small subunit methyltransferase
N8A75_08095	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N8A75_08100	COG3314	Sporulation integral membrane protein YlbJ
N8A75_08105	COG1752	Esterase of the alpha-beta hydrolase superfamily
N8A75_08110	COG3480	Lon protease (S16) C-terminal proteolytic domain
N8A75_08115	COG1323	Belongs to the UPF0348 family
N8A75_08125	COG1399	metal-binding, possibly nucleic acid-binding protein
N8A75_08140	COG0454	-acetyltransferase
N8A75_08145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N8A75_08150	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
N8A75_08155	COG2001	Belongs to the MraZ family
N8A75_08160	COG0275	rRNA processing
N8A75_08165	COG4839	cell division protein FtsL
N8A75_08170	COG0768	penicillin binding
N8A75_08175	COG0768	penicillin binding
N8A75_08180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N8A75_08185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N8A75_08190	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N8A75_08195	COG0772	Belongs to the SEDS family
N8A75_08200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N8A75_08205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N8A75_08210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N8A75_08215	COG3879	Bacterial protein of unknown function (DUF881)
N8A75_08220	COG3879	Bacterial protein of unknown function (DUF881)
N8A75_08225	COG3856	small basic protein
N8A75_08230	COG0849	cell division
N8A75_08235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N8A75_08240	COG1404	Belongs to the peptidase S8 family
N8A75_08240	COG4412	M6 family metalloprotease domain protein
N8A75_08250	COG1191	sigma factor activity
N8A75_08255	COG1191	sigma factor activity
N8A75_08260	COG1119	ATPase activity
N8A75_08265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N8A75_08270	COG1873	PFAM PRC-barrel domain
N8A75_08275	COG1496	oxidoreductase activity
N8A75_08280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N8A75_08285	COG1799	cell septum assembly
N8A75_08290	COG0762	integral membrane protein
N8A75_08295	COG2302	S4 RNA-binding domain
N8A75_08300	COG3599	regulation of cell shape
N8A75_08305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N8A75_08315	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N8A75_08320	COG0564	pseudouridine synthase activity
N8A75_08325	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
N8A75_08330	COG2233	PERMEase
N8A75_08335	COG0540	Belongs to the ATCase OTCase family
N8A75_08340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N8A75_08345	COG0505	Belongs to the CarA family
N8A75_08350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N8A75_08355	COG0543	2 iron, 2 sulfur cluster binding
N8A75_08360	COG0167	dihydroorotate dehydrogenase activity
N8A75_08365	COG0284	orotidine-5'-phosphate decarboxylase activity
N8A75_08370	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N8A75_08375	COG0175	sulfate reduction
N8A75_08380	COG0306	phosphate transporter
N8A75_08385	COG2046	Belongs to the sulfate adenylyltransferase family
N8A75_08390	COG0529	Catalyzes the synthesis of activated sulfate
N8A75_08395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N8A75_08400	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
N8A75_08405	COG1648	precorrin-2 dehydrogenase activity
N8A75_08410	COG1293	RNA-binding protein homologous to eukaryotic snRNP
N8A75_08415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N8A75_08420	COG1561	YicC-like family, N-terminal region
N8A75_08430	COG0194	GDP metabolic process
N8A75_08435	COG1758	RNA polymerase activity
N8A75_08440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N8A75_08445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N8A75_08450	COG0242	peptide deformylase activity
N8A75_08455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N8A75_08460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N8A75_08460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N8A75_08465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N8A75_08470	COG0631	protein serine/threonine phosphatase activity
N8A75_08475	COG0515	serine threonine protein kinase
N8A75_08475	COG2815	serine threonine protein kinase
N8A75_08480	COG1162	GTPase activity
N8A75_08485	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N8A75_08490	COG1564	THIamine pyrophosphokinase
N8A75_08500	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N8A75_08505	COG1302	Protein conserved in bacteria
N8A75_08510	COG1461	Dihydroxyacetone kinase
N8A75_08515	COG1760	l-serine dehydratase
N8A75_08520	COG1760	l-serine dehydratase
N8A75_08525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N8A75_08530	COG2050	protein possibly involved in aromatic compounds catabolism
N8A75_08530	COG1349	DNA-binding transcription factor activity
N8A75_08535	COG0416	fatty acid biosynthetic process
N8A75_08540	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N8A75_08545	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_08555	COG0571	ribonuclease III activity
N8A75_08560	COG1196	nuclear chromosome segregation
N8A75_08565	COG0552	protein localization to endoplasmic reticulum
N8A75_08575	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
N8A75_08580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N8A75_08585	COG0228	four-way junction DNA binding
N8A75_08590	COG1837	Belongs to the UPF0109 family
N8A75_08600	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N8A75_08605	COG0336	Belongs to the RNA methyltransferase TrmD family
N8A75_08610	COG0335	large ribosomal subunit rRNA binding
N8A75_08615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N8A75_08620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N8A75_08630	COG2257	FlhB HrpN YscU SpaS Family
N8A75_08635	COG0045	succinate-CoA ligase (ADP-forming) activity
N8A75_08640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N8A75_08645	COG0758	DNA mediated transformation
N8A75_08650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N8A75_08655	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
N8A75_08660	COG4974	Belongs to the 'phage' integrase family
N8A75_08665	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N8A75_08670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N8A75_08675	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N8A75_08680	COG1815	bacterial-type flagellum-dependent cell motility
N8A75_08685	COG1558	bacterial-type flagellum-dependent cell motility
N8A75_08690	COG1677	Flagellar hook-basal body complex protein FliE
N8A75_08695	COG1766	The M ring may be actively involved in energy transduction
N8A75_08700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N8A75_08705	COG1317	bacterial-type flagellum organization
N8A75_08710	COG1157	protein secretion by the type III secretion system
N8A75_08715	COG2882	bacterial-type flagellum organization
N8A75_08720	COG3334	PFAM MgtE intracellular
N8A75_08725	COG3144	bacterial-type flagellum assembly
N8A75_08730	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N8A75_08735	COG4786	Flagellar basal body rod
N8A75_08740	COG1582	Flagellar protein (FlbD)
N8A75_08745	COG1580	Controls the rotational direction of flagella during chemotaxis
N8A75_08750	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N8A75_08755	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N8A75_08755	COG1776	CheC inhibitor of MCP methylation
N8A75_08760	COG2201	protein-glutamate methylesterase activity
N8A75_08765	COG3190	flagellar
N8A75_08770	COG1338	Plays a role in the flagellum-specific transport system
N8A75_08775	COG1987	bacterial-type flagellum assembly
N8A75_08780	COG1684	flagellar biosynthetic protein fliR
N8A75_08785	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N8A75_08790	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N8A75_08795	COG1419	protein localization to endoplasmic reticulum
N8A75_08800	COG0455	bacterial-type flagellum organization
N8A75_08805	COG2201	protein-glutamate methylesterase activity
N8A75_08810	COG2198	Histidine kinase
N8A75_08810	COG0643	Histidine kinase
N8A75_08815	COG0835	chemotaxis
N8A75_08820	COG1776	CheC inhibitor of MCP methylation
N8A75_08825	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N8A75_08830	COG1191	sigma factor activity
N8A75_08840	COG0052	Belongs to the universal ribosomal protein uS2 family
N8A75_08845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N8A75_08850	COG0528	UMP kinase activity
N8A75_08855	COG0233	cytoplasmic translational termination
N8A75_08860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N8A75_08865	COG4589	Belongs to the CDS family
N8A75_08870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N8A75_08875	COG0750	zinc metalloprotease
N8A75_08880	COG0442	prolyl-tRNA aminoacylation
N8A75_08885	COG2176	DNA-directed DNA polymerase activity
N8A75_08890	COG0779	Required for maturation of 30S ribosomal subunits
N8A75_08895	COG0195	Participates in both transcription termination and antitermination
N8A75_08900	COG2740	Nucleic-acid-binding protein implicated in transcription termination
N8A75_08905	COG1358	cellular component organization or biogenesis
N8A75_08910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N8A75_08915	COG1550	Protein conserved in bacteria
N8A75_08920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N8A75_08925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N8A75_08930	COG0196	riboflavin kinase activity
N8A75_08935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N8A75_08940	COG1185	polyribonucleotide nucleotidyltransferase activity
N8A75_08945	COG0726	polysaccharide deacetylase
N8A75_08950	COG0612	Peptidase, M16
N8A75_08955	COG1873	PFAM PRC-barrel domain
N8A75_08960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N8A75_08965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N8A75_08970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N8A75_08975	COG0527	aspartate kinase activity
N8A75_08980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N8A75_08985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N8A75_08990	COG0740	serine-type endopeptidase activity
N8A75_09000	COG1674	ftsk spoiiie
N8A75_09000	COG4980	gas vesicle protein
N8A75_09005	COG2188	Transcriptional regulator
N8A75_09010	COG2814	Major facilitator Superfamily
N8A75_09015	COG0612	Peptidase, M16
N8A75_09020	COG0612	Peptidase, M16
N8A75_09025	COG0300	oxidoreductase activity
N8A75_09040	COG1426	Protein conserved in bacteria
N8A75_09045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N8A75_09050	COG1058	Belongs to the CinA family
N8A75_09050	COG1546	Belongs to the CinA family
N8A75_09055	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N8A75_09060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N8A75_09065	COG1418	mRNA catabolic process
N8A75_09070	COG1692	metallophosphoesterase
N8A75_09075	COG2359	stage V sporulation protein S
N8A75_09080	COG1063	alcohol dehydrogenase
N8A75_09085	COG0156	8-amino-7-oxononanoate synthase activity
N8A75_09090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N8A75_09095	COG4550	Control of competence regulator ComK, YlbF/YmcA
N8A75_09105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N8A75_09110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N8A75_09150	COG0582	viral genome integration into host DNA
N8A75_09200	COG3226	Transcriptional regulator
N8A75_09210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8A75_09215	COG1404	Belongs to the peptidase S8 family
N8A75_09225	COG4195	phage-related replication protein
N8A75_09230	COG1764	response to oxidative stress
N8A75_09235	COG2076	Multidrug Resistance protein
N8A75_09240	COG2076	Multidrug Resistance protein
N8A75_09255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N8A75_09260	COG1923	regulation of RNA biosynthetic process
N8A75_09275	COG1780	Probably involved in ribonucleotide reductase function
N8A75_09280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N8A75_09285	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N8A75_09290	COG4112	unkown
N8A75_09295	COG0860	N-Acetylmuramoyl-L-alanine amidase
N8A75_09315	COG1525	nuclease
N8A75_09325	COG4282	regulation of fungal-type cell wall biogenesis
N8A75_09335	COG5444	nuclease activity
N8A75_09365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N8A75_09375	COG0457	Tetratricopeptide repeat
N8A75_09390	COG5632	N-Acetylmuramoyl-L-alanine amidase
N8A75_09405	COG2433	Pfam Transposase IS66
N8A75_09415	COG1196	nuclear chromosome segregation
N8A75_09415	COG0741	lytic transglycosylase activity
N8A75_09415	COG0739	heme binding
N8A75_09440	COG0582	viral genome integration into host DNA
N8A75_09540	COG4373	Mu-like prophage FluMu protein gp28
N8A75_09575	COG0776	regulation of translation
N8A75_09670	COG3655	Transcriptional regulator
N8A75_09740	COG0582	viral genome integration into host DNA
N8A75_09755	COG3655	Transcriptional regulator
N8A75_09860	COG1793	dna ligase
N8A75_09865	COG2135	peptidase activity
N8A75_09885	COG4195	phage-related replication protein
N8A75_09890	COG3420	alginic acid biosynthetic process
N8A75_09890	COG5434	Belongs to the glycosyl hydrolase 28 family
N8A75_09915	COG2887	Belongs to the helicase family. UvrD subfamily
N8A75_09925	COG0305	Participates in initiation and elongation during chromosome replication
N8A75_09930	COG0358	DNA primase activity
N8A75_09935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N8A75_09940	COG0587	DNA-directed DNA polymerase activity
N8A75_09945	COG3584	3D domain protein
N8A75_09970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N8A75_09985	COG0270	DNA (cytosine-5-)-methyltransferase activity
N8A75_10070	COG1780	Probably involved in ribonucleotide reductase function
N8A75_10075	COG1372	Participates in initiation and elongation during chromosome replication
N8A75_10075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N8A75_10085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N8A75_10090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8A75_10095	COG0756	dUTP diphosphatase activity
N8A75_10125	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N8A75_10145	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N8A75_10205	COG3331	DNA recombination
N8A75_10225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N8A75_10230	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
N8A75_10235	COG0789	Transcriptional regulator
N8A75_10240	COG0174	glutamine synthetase
N8A75_10260	COG4282	regulation of fungal-type cell wall biogenesis
N8A75_10275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8A75_10290	COG3655	Transcriptional regulator
N8A75_10315	COG0135	phosphoribosylanthranilate isomerase activity
N8A75_10325	COG2211	Major facilitator Superfamily
N8A75_10330	COG3507	Belongs to the glycosyl hydrolase 43 family
N8A75_10335	COG1940	carbohydrate kinase activity
N8A75_10340	COG2115	Belongs to the xylose isomerase family
N8A75_10345	COG1070	Carbohydrate kinase
N8A75_10355	COG1525	nuclease
N8A75_10360	COG2814	Major facilitator Superfamily
N8A75_10365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N8A75_10380	COG0756	dUTP diphosphatase activity
N8A75_10420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N8A75_10435	COG3832	glyoxalase III activity
N8A75_10475	COG4195	phage-related replication protein
N8A75_10485	COG0346	lactoylglutathione lyase activity
N8A75_10495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N8A75_10500	COG1388	LysM domain
N8A75_10505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N8A75_10510	COG4224	UPF0291 protein
N8A75_10515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N8A75_10525	COG3763	UPF0154 protein
N8A75_10535	COG0785	Cytochrome C biogenesis protein
N8A75_10540	COG2201	protein-glutamate methylesterase activity
N8A75_10545	COG4846	Membrane protein involved in cytochrome C biogenesis
N8A75_10555	COG0071	Belongs to the small heat shock protein (HSP20) family
N8A75_10570	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N8A75_10575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8A75_10595	COG0824	Thioesterase
N8A75_10605	COG4841	protein insertion into membrane
N8A75_10610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N8A75_10615	COG1832	CoA-binding protein
N8A75_10620	COG0187	DNA topoisomerase II activity
N8A75_10625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N8A75_10640	COG1115	amino acid carrier protein
N8A75_10645	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
N8A75_10655	COG5520	Belongs to the glycosyl hydrolase 30 family
N8A75_10660	COG3507	Belongs to the glycosyl hydrolase 43 family
N8A75_10665	COG2246	polysaccharide biosynthetic process
N8A75_10670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N8A75_10675	COG0586	Pfam SNARE associated Golgi protein
N8A75_10680	COG2404	hydrolase activity, acting on ester bonds
N8A75_10685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N8A75_10690	COG1024	Enoyl-CoA hydratase
N8A75_10695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N8A75_10700	COG0511	ligase activity, forming carbon-carbon bonds
N8A75_10705	COG0439	Biotin carboxylase
N8A75_10710	COG0318	PFAM AMP-dependent synthetase and ligase
N8A75_10715	COG1960	acyl-CoA dehydrogenase activity
N8A75_10730	COG1649	PFAM Uncharacterised BCR, COG1649
N8A75_10745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8A75_10750	COG2027	D-alanyl-D-alanine carboxypeptidase
N8A75_10755	COG2017	converts alpha-aldose to the beta-anomer
N8A75_10760	COG0534	Mate efflux family protein
N8A75_10775	COG0582	viral genome integration into host DNA
N8A75_10780	COG0166	Belongs to the GPI family
N8A75_10785	COG0405	Gamma-glutamyltransferase
N8A75_10790	COG0583	DNA-binding transcription factor activity
N8A75_10795	COG0604	alcohol dehydrogenase
N8A75_10800	COG0493	'glutamate synthase
N8A75_10805	COG0070	glutamate synthase
N8A75_10805	COG0069	glutamate synthase activity
N8A75_10805	COG0067	glutamate synthase
N8A75_10810	COG0583	DNA-binding transcription factor activity
N8A75_10815	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N8A75_10820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N8A75_10830	COG0300	oxidoreductase activity
N8A75_10835	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N8A75_10845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8A75_10860	COG1131	(ABC) transporter
N8A75_10870	COG2814	Major facilitator Superfamily
N8A75_10875	COG1070	Carbohydrate kinase
N8A75_10880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N8A75_10885	COG0243	molybdopterin cofactor binding
N8A75_10915	COG5278	phosphoserine phosphatase activity
N8A75_10915	COG0840	transmembrane signaling receptor activity
N8A75_10920	COG2368	4-hydroxyphenylacetate
N8A75_10925	COG4305	rare lipoprotein A
N8A75_10930	COG3619	membrane
N8A75_10935	COG3866	Pectate lyase
N8A75_10940	COG2135	peptidase activity
N8A75_10950	COG2140	Oxalate decarboxylase
N8A75_10980	COG2720	vancomycin resistance protein
N8A75_10995	COG3739	integral membrane protein
N8A75_11000	COG0583	DNA-binding transcription factor activity
N8A75_11005	COG0697	spore germination
N8A75_11015	COG0693	protein deglycase activity
N8A75_11020	COG2367	Beta-lactamase
N8A75_11050	COG0726	polysaccharide deacetylase
N8A75_11060	COG2314	TM2 domain
N8A75_11175	COG0457	Tetratricopeptide repeat
N8A75_11180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8A75_11190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N8A75_11195	COG2226	methyltransferase
N8A75_11200	COG2211	Major facilitator Superfamily
N8A75_11250	COG5444	nuclease activity
N8A75_11255	COG4282	regulation of fungal-type cell wall biogenesis
N8A75_11260	COG1231	oxidoreductase activity
N8A75_11265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N8A75_11270	COG2207	Transcriptional regulator
N8A75_11270	COG0662	Cupin 2, conserved barrel domain protein
N8A75_11275	COG0456	acetyltransferase
N8A75_11280	COG1309	transcriptional regulator
N8A75_11285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8A75_11290	COG3708	Transcriptional regulator
N8A75_11295	COG2378	regulation of single-species biofilm formation
N8A75_11305	COG0640	Transcriptional regulator
N8A75_11310	COG0741	lytic transglycosylase activity
N8A75_11315	COG2322	membrane
N8A75_11330	COG1619	proteins homologs of microcin C7 resistance protein MccF
N8A75_11335	COG3239	Fatty acid desaturase
N8A75_11340	COG4585	Histidine kinase
N8A75_11345	COG2197	response regulator
N8A75_11350	COG1388	LysM domain
N8A75_11350	COG3584	3D domain protein
N8A75_11355	COG0514	ATP-dependent DNA helicase (RecQ)
N8A75_11365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N8A75_11370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N8A75_11385	COG0071	Belongs to the small heat shock protein (HSP20) family
N8A75_11410	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_11415	COG1657	PFAM Prenyltransferase squalene oxidase
N8A75_11420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N8A75_11425	COG0733	neurotransmitter:sodium symporter activity
N8A75_11430	COG0385	Bile acid
N8A75_11435	COG0508	dehydrogenase complex catalyzes the overall conversion of
N8A75_11440	COG0567	Dehydrogenase, E1 component
N8A75_11445	COG4548	von Willebrand factor, type A
N8A75_11450	COG0714	Associated with various cellular activities
N8A75_11455	COG2032	superoxide dismutase activity
N8A75_11460	COG0791	NLP P60 protein
N8A75_11460	COG1388	LysM domain
N8A75_11465	COG1819	glycosyl
N8A75_11470	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N8A75_11475	COG0534	Mate efflux family protein
N8A75_11480	COG1366	Belongs to the anti-sigma-factor antagonist family
N8A75_11485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N8A75_11490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N8A75_11500	COG2962	Rard protein
N8A75_11515	COG2610	gluconate transmembrane transporter activity
N8A75_11520	COG2610	gluconate transmembrane transporter activity
N8A75_11525	COG1942	4-Oxalocrotonate Tautomerase
N8A75_11530	COG1733	regulation of RNA biosynthetic process
N8A75_11535	COG0778	Nitroreductase
N8A75_11540	COG0400	carboxylic ester hydrolase activity
N8A75_11545	COG0346	lactoylglutathione lyase activity
N8A75_11555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8A75_11560	COG0793	Belongs to the peptidase S41A family
N8A75_11560	COG3409	Peptidoglycan-binding domain 1 protein
N8A75_11565	COG2226	methyltransferase
N8A75_11575	COG1876	peptidase activity
N8A75_11580	COG0813	purine-nucleoside phosphorylase activity
N8A75_11595	COG0671	phosphoesterase, PA-phosphatase related
N8A75_11615	COG4479	Belongs to the UPF0346 family
N8A75_11625	COG1509	lysine 2,3-aminomutase activity
N8A75_11630	COG0456	acetyltransferase
N8A75_11635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N8A75_11640	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N8A75_11645	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N8A75_11650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N8A75_11665	COG0456	acetyltransferase
N8A75_11670	COG0463	Glycosyl transferase, family 2
N8A75_11685	COG4641	Protein conserved in bacteria
N8A75_11690	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
N8A75_11695	COG1086	Polysaccharide biosynthesis protein
N8A75_11700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N8A75_11705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N8A75_11710	COG1846	Transcriptional regulator
N8A75_11715	COG0534	Mate efflux family protein
N8A75_11725	COG4698	Protein conserved in bacteria
N8A75_11730	COG2755	lipolytic protein G-D-S-L family
N8A75_11735	COG1999	signal sequence binding
N8A75_11745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N8A75_11750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N8A75_11755	COG1272	protein, Hemolysin III
N8A75_11760	COG0204	Acyl-transferase
N8A75_11765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N8A75_11770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N8A75_11780	COG2521	methyltransferase
N8A75_11780	COG2136	Putative SAM-dependent methyltransferase
N8A75_11790	COG0129	dihydroxy-acid dehydratase activity
N8A75_11795	COG1413	lyase activity
N8A75_11800	COG1418	mRNA catabolic process
N8A75_11805	COG0386	Belongs to the glutathione peroxidase family
N8A75_11810	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
N8A75_11815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N8A75_11825	COG1278	Cold shock
N8A75_11845	COG0328	RNA-DNA hybrid ribonuclease activity
N8A75_11850	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N8A75_11855	COG0328	RNA-DNA hybrid ribonuclease activity
N8A75_11865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N8A75_11880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N8A75_11890	COG1755	Isoprenylcysteine carboxyl methyltransferase
N8A75_11895	COG3424	synthase
N8A75_11900	COG2233	PERMEase
N8A75_11905	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N8A75_11910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N8A75_11920	COG0800	Aldolase
N8A75_11925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8A75_11930	COG1609	Transcriptional regulator
N8A75_11935	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
N8A75_11940	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_11945	COG1199	ATP-dependent helicase activity
N8A75_11960	COG0116	Belongs to the methyltransferase superfamily
N8A75_11975	COG4474	Belongs to the UPF0398 family
N8A75_11990	COG3359	exonuclease
N8A75_11995	COG1111	helicase
N8A75_11995	COG1205	dead DEAH box helicase
N8A75_12000	COG2190	(PTS) system
N8A75_12005	COG0071	Belongs to the small heat shock protein (HSP20) family
N8A75_12040	COG3331	DNA recombination
N8A75_12045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N8A75_12045	COG4499	WXG100 protein secretion system (Wss), protein YukC
N8A75_12055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N8A75_12060	COG3935	DnaD domain protein
N8A75_12065	COG0017	Asparaginyl-tRNA synthetase
N8A75_12070	COG0436	Aminotransferase
N8A75_12075	COG5353	protein conserved in bacteria
N8A75_12085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N8A75_12085	COG1199	ATP-dependent helicase activity
N8A75_12090	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
N8A75_12095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N8A75_12100	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N8A75_12105	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
N8A75_12105	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
N8A75_12110	COG0617	tRNA 3'-terminal CCA addition
N8A75_12115	COG0438	transferase activity, transferring glycosyl groups
N8A75_12120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N8A75_12125	COG1803	Methylglyoxal synthase
N8A75_12130	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N8A75_12135	COG1694	Mazg nucleotide pyrophosphohydrolase
N8A75_12140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N8A75_12150	COG4347	Protein of unknown function (DUF1405)
N8A75_12155	COG2010	Cytochrome c
N8A75_12155	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N8A75_12160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N8A75_12165	COG0723	plastoquinol--plastocyanin reductase activity
N8A75_12175	COG5582	Belongs to the UPF0302 family
N8A75_12180	COG0457	Tetratricopeptide repeat
N8A75_12185	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N8A75_12190	COG0287	Prephenate dehydrogenase
N8A75_12195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N8A75_12200	COG0159	tryptophan synthase activity
N8A75_12205	COG0133	tryptophan synthase activity
N8A75_12210	COG0135	phosphoribosylanthranilate isomerase activity
N8A75_12220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N8A75_12225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N8A75_12230	COG4401	Chorismate mutase type I
N8A75_12235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N8A75_12240	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N8A75_12245	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N8A75_12250	COG0105	UTP biosynthetic process
N8A75_12255	COG0142	geranyltranstransferase activity
N8A75_12260	COG2226	methyltransferase
N8A75_12265	COG0142	geranyltranstransferase activity
N8A75_12275	COG0302	gtp cyclohydrolase
N8A75_12280	COG0776	regulation of translation
N8A75_12285	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N8A75_12300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N8A75_12305	COG1160	GTP binding
N8A75_12330	COG1304	FMN binding
N8A75_12335	COG0539	negative regulation of cytoplasmic translation
N8A75_12340	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N8A75_12350	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
N8A75_12355	COG2959	enzyme of heme biosynthesis
N8A75_12360	COG3773	Cell wall hydrolase
N8A75_12360	COG3409	Peptidoglycan-binding domain 1 protein
N8A75_12365	COG2339	peptidase activity
N8A75_12370	COG0492	ferredoxin-NADP+ reductase activity
N8A75_12375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N8A75_12380	COG4862	establishment of competence for transformation
N8A75_12385	COG1408	metallophosphoesterase
N8A75_12395	COG1388	LysM domain
N8A75_12400	COG1266	CAAX protease self-immunity
N8A75_12405	COG0514	ATP-dependent DNA helicase (RecQ)
N8A75_12410	COG4955	Helix-turn-helix domain
N8A75_12415	COG1141	Ferredoxin
N8A75_12420	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
N8A75_12425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N8A75_12430	COG0710	3-dehydroquinate dehydratase activity
N8A75_12440	COG1595	DNA-templated transcription, initiation
N8A75_12445	COG5002	protein histidine kinase activity
N8A75_12450	COG0745	RESPONSE REGULATOR receiver
N8A75_12455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N8A75_12460	COG1333	cytochrome c biogenesis protein
N8A75_12465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8A75_12470	COG1187	pseudouridine synthase activity
N8A75_12475	COG0700	Nucleoside recognition
N8A75_12480	COG2715	membrane protein required for spore maturation
N8A75_12485	COG1686	Belongs to the peptidase S11 family
N8A75_12495	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N8A75_12500	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N8A75_12505	COG1547	Domain of unknown function (DUF309)
N8A75_12510	COG0456	acetyltransferase
N8A75_12515	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N8A75_12520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N8A75_12520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N8A75_12525	COG0307	riboflavin synthase, alpha
N8A75_12530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N8A75_12530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N8A75_12540	COG0681	Belongs to the peptidase S26 family
N8A75_12550	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
N8A75_12570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N8A75_12575	COG4086	secreted protein
N8A75_12580	COG0019	diaminopimelate decarboxylase activity
N8A75_12585	COG0697	spore germination
N8A75_12600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8A75_12620	COG1191	sigma factor activity
N8A75_12625	COG2172	sigma factor antagonist activity
N8A75_12630	COG1366	Belongs to the anti-sigma-factor antagonist family
N8A75_12635	COG1686	Belongs to the peptidase S11 family
N8A75_12640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
N8A75_12645	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N8A75_12650	COG4974	Belongs to the 'phage' integrase family
N8A75_12660	COG0735	belongs to the Fur family
N8A75_12665	COG1300	Membrane
N8A75_12675	COG0281	malic enzyme
N8A75_12680	COG1757	Na H antiporter
N8A75_12685	COG1027	Aspartate ammonia-lyase
N8A75_12690	COG0252	asparaginase activity
N8A75_12695	COG1396	sequence-specific DNA binding
N8A75_12700	COG1379	DNA repair
N8A75_12705	COG0494	nUDIX hydrolase
N8A75_12715	COG0667	Aldo Keto reductase
N8A75_12725	COG1073	alpha beta
N8A75_12735	COG4918	Iron-sulphur cluster biosynthesis
N8A75_12740	COG0456	acetyltransferase
N8A75_12740	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N8A75_12745	COG2329	Antibiotic biosynthesis monooxygenase
N8A75_12750	COG0456	acetyltransferase
N8A75_12760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N8A75_12770	COG2211	Major facilitator Superfamily
N8A75_12780	COG0346	lactoylglutathione lyase activity
N8A75_12785	COG1072	(Pantothenic acid kinase))
N8A75_12790	COG3048	D-serine ammonia-lyase activity
N8A75_12795	COG0300	oxidoreductase activity
N8A75_12800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8A75_12805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N8A75_12810	COG4187	Peptidase family M20/M25/M40
N8A75_12815	COG1902	pentaerythritol trinitrate reductase activity
N8A75_12820	COG0596	Alpha beta hydrolase
N8A75_12830	COG1234	tRNA 3'-trailer cleavage
N8A75_12835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N8A75_12840	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N8A75_12845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N8A75_12855	COG0706	membrane insertase activity
N8A75_12860	COG3361	conserved protein (COG2071)
N8A75_12865	COG2195	Cleaves the N-terminal amino acid of tripeptides
N8A75_12870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N8A75_12875	COG0346	lactoylglutathione lyase activity
N8A75_12885	COG1376	ErfK ybiS ycfS ynhG family protein
N8A75_12890	COG4129	membrane
N8A75_12895	COG1126	abc transporter atp-binding protein
N8A75_12900	COG0765	amino acid transport
N8A75_12905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8A75_12915	COG1597	lipid kinase activity
N8A75_12920	COG2814	Major facilitator Superfamily
N8A75_12925	COG4978	Transcriptional regulator
N8A75_12925	COG0789	Transcriptional regulator
N8A75_12930	COG0508	dehydrogenase complex catalyzes the overall conversion of
N8A75_12935	COG0022	dehydrogenase e1 component
N8A75_12940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N8A75_12945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N8A75_12950	COG3426	butyrate kinase activity
N8A75_12955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N8A75_12960	COG0280	phosphate acetyltransferase
N8A75_12965	COG3829	transcription factor binding
N8A75_12965	COG3290	protein histidine kinase activity
N8A75_12975	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N8A75_12980	COG2079	MmgE PrpD family protein
N8A75_12985	COG0372	Belongs to the citrate synthase family
N8A75_12990	COG1960	acyl-CoA dehydrogenase activity
N8A75_12995	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8A75_13000	COG0183	Belongs to the thiolase family
N8A75_13005	COG0584	glycerophosphoryl diester phosphodiesterase
N8A75_13010	COG0860	N-Acetylmuramoyl-L-alanine amidase
N8A75_13025	COG1902	pentaerythritol trinitrate reductase activity
N8A75_13030	COG0745	RESPONSE REGULATOR receiver
N8A75_13035	COG0750	zinc metalloprotease
N8A75_13040	COG0497	DNA recombination
N8A75_13045	COG1438	arginine binding
N8A75_13050	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
N8A75_13055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N8A75_13060	COG0142	geranyltranstransferase activity
N8A75_13065	COG1722	exodeoxyribonuclease VII activity
N8A75_13070	COG1570	exodeoxyribonuclease VII activity
N8A75_13075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N8A75_13080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N8A75_13085	COG1302	Protein conserved in bacteria
N8A75_13090	COG0439	Biotin carboxylase
N8A75_13095	COG0511	ligase activity, forming carbon-carbon bonds
N8A75_13135	COG3854	ATPases associated with a variety of cellular activities
N8A75_13145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N8A75_13150	COG0006	proline dipeptidase activity
N8A75_13155	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N8A75_13165	COG3872	metal-dependent enzyme
N8A75_13175	COG1752	Esterase of the alpha-beta hydrolase superfamily
N8A75_13180	COG1321	iron dependent repressor
N8A75_13185	COG0095	Lipoate-protein ligase
N8A75_13190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N8A75_13195	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N8A75_13200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N8A75_13205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N8A75_13210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N8A75_13225	COG1396	sequence-specific DNA binding
N8A75_13235	COG0681	Belongs to the peptidase S26 family
N8A75_13260	COG4940	Competence protein ComGF
N8A75_13270	COG4970	Tfp pilus assembly protein FimT
N8A75_13275	COG4537	Required for transformation and DNA binding
N8A75_13280	COG1459	type II secretion system
N8A75_13285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N8A75_13290	COG0517	IMP dehydrogenase activity
N8A75_13295	COG0598	Magnesium transport protein CorA
N8A75_13300	COG1253	flavin adenine dinucleotide binding
N8A75_13305	COG1366	Belongs to the anti-sigma-factor antagonist family
N8A75_13315	COG1393	Belongs to the ArsC family
N8A75_13325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8A75_13335	COG0011	TIGRFAM Protein of
N8A75_13345	COG2866	Carboxypeptidase
N8A75_13350	COG1368	sulfuric ester hydrolase activity
N8A75_13355	COG1940	carbohydrate kinase activity
N8A75_13360	COG4483	Protein conserved in bacteria
N8A75_13365	COG0457	Tetratricopeptide repeat
N8A75_13365	COG0705	Rhomboid family
N8A75_13375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N8A75_13385	COG0438	transferase activity, transferring glycosyl groups
N8A75_13400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N8A75_13405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N8A75_13410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N8A75_13415	COG0581	inorganic phosphate transmembrane transporter activity
N8A75_13420	COG0573	inorganic phosphate transmembrane transporter activity
N8A75_13425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N8A75_13430	COG0768	penicillin binding
N8A75_13435	COG0477	Major facilitator Superfamily
N8A75_13440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N8A75_13445	COG2839	Protein conserved in bacteria
N8A75_13450	COG5521	maltodextrose utilization protein MalA
N8A75_13455	COG1388	LysM domain
N8A75_13460	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N8A75_13465	COG4709	membrane
N8A75_13470	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
N8A75_13475	COG0735	belongs to the Fur family
N8A75_13480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N8A75_13490	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N8A75_13495	COG0513	Belongs to the DEAD box helicase family
N8A75_13505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N8A75_13510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N8A75_13515	COG2384	SAM-dependent methyltransferase
N8A75_13520	COG2010	Cytochrome c
N8A75_13525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N8A75_13530	COG0358	DNA primase activity
N8A75_13535	COG1671	Belongs to the UPF0178 family
N8A75_13540	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N8A75_13545	COG0517	IMP dehydrogenase activity
N8A75_13550	COG0751	glycine-tRNA ligase activity
N8A75_13555	COG0752	glycyl-tRNA synthetase alpha subunit
N8A75_13560	COG1381	Involved in DNA repair and RecF pathway recombination
N8A75_13570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N8A75_13575	COG0295	cytidine deaminase activity
N8A75_13580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N8A75_13585	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N8A75_13590	COG1480	7TM receptor with intracellular HD hydrolase
N8A75_13595	COG1702	phosphate starvation-inducible protein PhoH
N8A75_13600	COG0561	phosphatase activity
N8A75_13615	COG4864	UPF0365 protein
N8A75_13620	COG1030	water channel activity
N8A75_13625	COG1610	YqeY-like protein
N8A75_13635	COG1283	sodium-dependent phosphate transmembrane transporter activity
N8A75_13640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N8A75_13645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N8A75_13650	COG2264	protein methyltransferase activity
N8A75_13655	COG0484	heat shock protein binding
N8A75_13660	COG0443	Heat shock 70 kDa protein
N8A75_13665	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N8A75_13670	COG1420	regulation of RNA biosynthetic process
N8A75_13675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N8A75_13680	COG0481	GTPase activity
N8A75_13690	COG0860	N-Acetylmuramoyl-L-alanine amidase
N8A75_13695	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
N8A75_13700	COG0268	Binds directly to 16S ribosomal RNA
N8A75_13705	COG1466	dna polymerase III delta subunit
N8A75_13720	COG0658	competence protein
N8A75_13720	COG2333	competence protein COMEC
N8A75_13725	COG2131	deaminase
N8A75_13730	COG1555	photosystem II stabilization
N8A75_13730	COG1596	polysaccharide export
N8A75_13735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N8A75_13740	COG2226	methyltransferase
N8A75_13745	COG0799	negative regulation of ribosome biogenesis
N8A75_13750	COG1713	HD superfamily hydrolase involved in NAD metabolism
N8A75_13755	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N8A75_13760	COG1534	Rna-binding protein
N8A75_13765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N8A75_13770	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N8A75_13775	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
N8A75_13785	COG2755	lipolytic protein G-D-S-L family
N8A75_13790	COG3409	Peptidoglycan-binding domain 1 protein
N8A75_13790	COG5632	N-Acetylmuramoyl-L-alanine amidase
N8A75_13795	COG0398	Pfam SNARE associated Golgi protein
N8A75_13800	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
N8A75_13810	COG3209	COG3209 Rhs family protein
N8A75_13820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N8A75_13830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N8A75_13835	COG0798	PFAM Bile acid sodium symporter
N8A75_13840	COG0346	lactoylglutathione lyase activity
N8A75_13845	COG0640	Transcriptional regulator
N8A75_13850	COG3403	YqcI/YcgG family
N8A75_13855	COG0457	Tetratricopeptide repeat
N8A75_13870	COG5444	nuclease activity
N8A75_13895	COG5632	N-Acetylmuramoyl-L-alanine amidase
N8A75_13895	COG3409	Peptidoglycan-binding domain 1 protein
N8A75_13900	COG4824	toxin secretion phage lysis holin
N8A75_13930	COG3778	Protein conserved in bacteria
N8A75_13935	COG3299	homolog of phage Mu protein gp47
N8A75_13940	COG3628	GPW Gp25 family protein
N8A75_13950	COG4193	domain, Protein
N8A75_13955	COG1652	LysM domain
N8A75_13960	COG5280	Phage tail tape measure protein TP901
N8A75_13960	COG3953	SLT domain
N8A75_14025	COG4653	Phage capsid family
N8A75_14030	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N8A75_14040	COG2369	cell adhesion
N8A75_14045	COG5518	Phage portal protein
N8A75_14050	COG1783	phage Terminase large subunit
N8A75_14055	COG5484	DNA packaging
N8A75_14065	COG3677	Transposase
N8A75_14080	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
N8A75_14090	COG1484	DNA-dependent DNA replication
N8A75_14095	COG3935	DnaD domain protein
N8A75_14100	COG3723	Recombinational DNA repair protein, rece pathway
N8A75_14105	COG5377	YqaJ viral recombinase family
N8A75_14135	COG1476	TRANSCRIPTIONal
N8A75_14140	COG3620	sequence-specific DNA binding
N8A75_14150	COG0563	adenylate kinase activity
N8A75_14155	COG2856	Zn peptidase
N8A75_14175	COG0114	fumarate hydratase activity
N8A75_14180	COG0583	DNA-binding transcription factor activity
N8A75_14195	COG0457	Tetratricopeptide repeat
N8A75_14330	COG0789	Transcriptional regulator
N8A75_14330	COG4978	Transcriptional regulator
N8A75_14335	COG2814	Major facilitator Superfamily
N8A75_14340	COG0456	acetyltransferase
N8A75_14345	COG1253	flavin adenine dinucleotide binding
N8A75_14355	COG0697	spore germination
N8A75_14360	COG0583	DNA-binding transcription factor activity
N8A75_14365	COG2072	flavoprotein involved in K transport
N8A75_14370	COG1230	cation diffusion facilitator family transporter
N8A75_14385	COG1114	Component of the transport system for branched-chain amino acids
N8A75_14390	COG1687	branched-chain amino acid
N8A75_14395	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N8A75_14400	COG1522	sequence-specific DNA binding
N8A75_14405	COG2732	(Barnase) inhibitor
N8A75_14410	COG2124	cytochrome p450
N8A75_14420	COG1335	isochorismatase
N8A75_14440	COG2318	DinB family
N8A75_14450	COG2070	2-Nitropropane dioxygenase
N8A75_14455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N8A75_14475	COG3443	Belongs to the bacterial solute-binding protein 9 family
N8A75_14480	COG1595	DNA-templated transcription, initiation
N8A75_14485	COG0667	Aldo Keto reductase
N8A75_14490	COG2851	Citrate transporter
N8A75_14495	COG0583	DNA-binding transcription factor activity
N8A75_14500	COG2828	Protein conserved in bacteria
N8A75_14505	COG3409	Peptidoglycan-binding domain 1 protein
N8A75_14510	COG5566	PFAM Mor transcription activator
N8A75_14515	COG0596	Alpha beta hydrolase
N8A75_14520	COG4991	sh3 domain protein
N8A75_14525	COG4991	sh3 domain protein
N8A75_14535	COG0346	lactoylglutathione lyase activity
N8A75_14545	COG5577	PFAM Coat F domain
N8A75_14550	COG1063	alcohol dehydrogenase
N8A75_14560	COG5577	PFAM Coat F domain
N8A75_14565	COG0789	Transcriptional regulator
N8A75_14575	COG1064	alcohol dehydrogenase
N8A75_14580	COG0693	protein deglycase activity
N8A75_14585	COG1621	beta-fructofuranosidase activity
N8A75_14590	COG3716	PTS system mannose fructose sorbose family IID component
N8A75_14595	COG3715	PTS system
N8A75_14600	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8A75_14605	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8A75_14610	COG3933	PFAM sigma-54 factor interaction domain-containing protein
N8A75_14610	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N8A75_14620	COG1113	amino acid transport
N8A75_14625	COG1280	lysine exporter protein (LysE YggA)
N8A75_14630	COG1378	Sugar-specific transcriptional regulator TrmB
N8A75_14635	COG1595	DNA-templated transcription, initiation
N8A75_14645	COG2755	lipolytic protein G-D-S-L family
N8A75_14645	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N8A75_14655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N8A75_14655	COG2124	cytochrome p450
N8A75_14660	COG1309	transcriptional regulator
N8A75_14665	COG2226	methyltransferase
N8A75_14680	COG2116	formate transmembrane transporter activity
N8A75_14685	COG5609	conserved protein (DUF2294)
N8A75_14690	COG3383	formate dehydrogenase (NAD+) activity
N8A75_14695	COG2427	Protein of unknown function (DUF1641)
N8A75_14705	COG0626	cystathionine gamma-synthase activity
N8A75_14710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N8A75_14715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N8A75_14720	COG2226	methyltransferase
N8A75_14735	COG0768	penicillin binding
N8A75_14740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N8A75_14745	COG0572	uridine kinase
N8A75_14750	COG0826	peptidase U32
N8A75_14755	COG0826	peptidase U32
N8A75_14760	COG4122	O-methyltransferase activity
N8A75_14765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N8A75_14770	COG3906	Belongs to the UPF0473 family
N8A75_14775	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N8A75_14780	COG4472	Bacterial protein of unknown function (DUF965)
N8A75_14785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N8A75_14790	COG0628	permease
N8A75_14795	COG1126	abc transporter atp-binding protein
N8A75_14800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8A75_14805	COG0765	amino acid transport
N8A75_14810	COG0765	amino acid transport
N8A75_14825	COG3881	PFAM PRC-barrel domain
N8A75_14830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N8A75_14835	COG0457	Tetratricopeptide repeat
N8A75_14840	COG0482	sulfurtransferase activity
N8A75_14845	COG1104	cysteine desulfurase activity
N8A75_14850	COG1959	2 iron, 2 sulfur cluster binding
N8A75_14855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N8A75_14860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N8A75_14870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N8A75_14875	COG0124	histidyl-tRNA synthetase
N8A75_14885	COG4991	sh3 domain protein
N8A75_14885	COG3103	Sh3 type 3 domain protein
N8A75_14885	COG0860	N-Acetylmuramoyl-L-alanine amidase
N8A75_14890	COG1490	D-aminoacyl-tRNA deacylase activity
N8A75_14895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N8A75_14900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N8A75_14905	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
N8A75_14905	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N8A75_14910	COG5416	Lipopolysaccharide assembly protein A domain
N8A75_14915	COG0490	domain, Protein
N8A75_14920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N8A75_14920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N8A75_14930	COG2244	polysaccharide biosynthetic process
N8A75_14935	COG2323	membrane
N8A75_14945	COG1862	Preprotein translocase
N8A75_14950	COG0343	queuine tRNA-ribosyltransferase activity
N8A75_14955	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N8A75_14965	COG2255	four-way junction helicase activity
N8A75_14970	COG0632	four-way junction helicase activity
N8A75_14980	COG2814	Major facilitator Superfamily
N8A75_14985	COG0673	inositol 2-dehydrogenase activity
N8A75_14990	COG2112	serine threonine protein kinase
N8A75_15015	COG1115	amino acid carrier protein
N8A75_15020	COG0217	transcriptional regulatory protein
N8A75_15030	COG1388	LysM domain
N8A75_15035	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N8A75_15040	COG0157	Belongs to the NadC ModD family
N8A75_15045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N8A75_15050	COG1104	cysteine desulfurase activity
N8A75_15055	COG1827	regulation of RNA biosynthetic process
N8A75_15060	COG0077	Prephenate dehydratase
N8A75_15065	COG4492	Belongs to the UPF0735 family
N8A75_15070	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N8A75_15075	COG3290	protein histidine kinase activity
N8A75_15085	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N8A75_15090	COG2868	ribosomal protein
N8A75_15095	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N8A75_15100	COG1994	Peptidase M50
N8A75_15105	COG0739	heme binding
N8A75_15110	COG2894	cell division
N8A75_15115	COG0850	regulation of cytokinetic process
N8A75_15120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N8A75_15130	COG1077	Cell shape determining protein MreB Mrl
N8A75_15135	COG2003	Belongs to the UPF0758 family
N8A75_15140	COG0424	maF-like protein
N8A75_15150	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
N8A75_15155	COG0285	dihydrofolate synthase activity
N8A75_15160	COG0525	valine-tRNA ligase activity
N8A75_15170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N8A75_15175	COG1388	LysM domain
N8A75_15180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N8A75_15185	COG0113	porphobilinogen synthase activity
N8A75_15190	COG1587	Uroporphyrinogen-III synthase
N8A75_15195	COG0181	hydroxymethylbilane synthase activity
N8A75_15200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N8A75_15205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N8A75_15215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
N8A75_15220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N8A75_15225	COG0470	DNA polymerase III
N8A75_15225	COG1067	ATP-dependent peptidase activity
N8A75_15230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N8A75_15235	COG0544	peptidyl-prolyl cis-trans isomerase activity
N8A75_15240	COG0457	Tetratricopeptide repeat
N8A75_15240	COG1477	protein flavinylation
N8A75_15245	COG0066	3-isopropylmalate dehydratase activity
N8A75_15250	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N8A75_15255	COG0473	3-isopropylmalate dehydrogenase activity
N8A75_15260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N8A75_15265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N8A75_15270	COG0440	acetolactate synthase activity
N8A75_15275	COG0028	Belongs to the TPP enzyme family
N8A75_15285	COG0454	-acetyltransferase
N8A75_15290	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
N8A75_15300	COG0622	Phosphoesterase
N8A75_15305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N8A75_15310	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N8A75_15315	COG5401	PFAM Sporulation and spore germination
N8A75_15320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N8A75_15325	COG1846	Transcriptional regulator
N8A75_15330	COG2197	response regulator
N8A75_15335	COG0824	Thioesterase
N8A75_15340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N8A75_15345	COG1053	succinate dehydrogenase
N8A75_15350	COG2009	succinate dehydrogenase
N8A75_15355	COG1719	4-vinyl reductase, 4VR
N8A75_15360	COG0527	aspartate kinase activity
N8A75_15365	COG0322	excinuclease ABC activity
N8A75_15370	COG3118	belongs to the thioredoxin family
N8A75_15380	COG3534	alpha-L-arabinofuranosidase
N8A75_15385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N8A75_15390	COG2086	electron transfer activity
N8A75_15395	COG1024	Enoyl-CoA hydratase
N8A75_15400	COG1309	transcriptional regulator
N8A75_15405	COG0318	PFAM AMP-dependent synthetase and ligase
N8A75_15410	COG3766	membrane
N8A75_15415	COG1193	negative regulation of DNA recombination
N8A75_15420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N8A75_15420	COG1796	DNA polymerase
N8A75_15425	COG1286	toxin biosynthetic process
N8A75_15430	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
N8A75_15435	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N8A75_15440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N8A75_15440	COG0072	phenylalanine-tRNA ligase activity
N8A75_15445	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N8A75_15455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N8A75_15465	COG3835	regulator
N8A75_15470	COG0277	FAD linked oxidase domain protein
N8A75_15475	COG0247	lactate metabolic process
N8A75_15480	COG0346	lactoylglutathione lyase activity
N8A75_15490	COG1966	Carbon starvation protein
N8A75_15495	COG3534	alpha-L-arabinofuranosidase
N8A75_15500	COG0395	ABC-type sugar transport system, permease component
N8A75_15505	COG1175	transmembrane transport
N8A75_15510	COG1653	transport
N8A75_15515	COG0371	Dehydrogenase
N8A75_15520	COG0647	UMP catabolic process
N8A75_15525	COG0235	Class ii aldolase
N8A75_15530	COG1069	ribulokinase activity
N8A75_15535	COG2160	L-arabinose isomerase activity
N8A75_15540	COG3507	Belongs to the glycosyl hydrolase 43 family
N8A75_15545	COG1363	Peptidase, m42
N8A75_15555	COG3326	Membrane
N8A75_15560	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N8A75_15565	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N8A75_15570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N8A75_15580	COG1346	cytolysis
N8A75_15585	COG1380	Effector of murein hydrolase LrgA
N8A75_15590	COG3279	Response regulator of the LytR AlgR family
N8A75_15595	COG3275	phosphorelay sensor kinase activity
N8A75_15600	COG1011	Hydrolase
N8A75_15605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N8A75_15615	COG0398	Pfam SNARE associated Golgi protein
N8A75_15620	COG1484	DNA-dependent DNA replication
N8A75_15625	COG3611	Membrane attachment protein
N8A75_15630	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N8A75_15635	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
N8A75_15640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N8A75_15645	COG1733	regulation of RNA biosynthetic process
N8A75_15650	COG2814	Major facilitator Superfamily
N8A75_15655	COG0656	L-ascorbic acid biosynthetic process
N8A75_15660	COG0237	dephospho-CoA kinase activity
N8A75_15670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N8A75_15675	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N8A75_15675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N8A75_15680	COG5002	protein histidine kinase activity
N8A75_15685	COG0745	RESPONSE REGULATOR receiver
N8A75_15690	COG0039	L-malate dehydrogenase activity
N8A75_15695	COG0538	isocitrate dehydrogenase activity
N8A75_15700	COG0372	Belongs to the citrate synthase family
N8A75_15705	COG2707	UPF0756 membrane protein
N8A75_15710	COG0628	permease
N8A75_15715	COG3030	protein affecting phage T7 exclusion by the F plasmid
N8A75_15720	COG0469	pyruvate kinase activity
N8A75_15725	COG0205	6-phosphofructokinase activity
N8A75_15730	COG0825	malonyl-CoA metabolic process
N8A75_15735	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N8A75_15740	COG0281	malic enzyme
N8A75_15745	COG0587	DNA-directed DNA polymerase activity
N8A75_15765	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N8A75_15775	COG4109	DRTGG domain
N8A75_15780	COG0730	response to heat
N8A75_15785	COG1473	amidohydrolase
N8A75_15790	COG0196	riboflavin kinase activity
N8A75_15795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8A75_15800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N8A75_15805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8A75_15810	COG1126	abc transporter atp-binding protein
N8A75_15815	COG0765	amino acid transport
N8A75_15820	COG0765	amino acid transport
N8A75_15825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8A75_15830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8A75_15835	COG0454	-acetyltransferase
N8A75_15840	COG0583	DNA-binding transcription factor activity
N8A75_15845	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N8A75_15850	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_15860	COG0165	Argininosuccinate lyase
N8A75_15865	COG0137	argininosuccinate synthase activity
N8A75_15870	COG0521	Mo-molybdopterin cofactor biosynthetic process
N8A75_15875	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N8A75_15885	COG0827	DNA restriction-modification system
N8A75_15890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
N8A75_15895	COG3874	Sporulation protein YtfJ
N8A75_15905	COG1714	RDD family
N8A75_15910	COG0616	signal peptide processing
N8A75_15915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N8A75_15920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
N8A75_15925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N8A75_15935	COG0301	tRNA thio-modification
N8A75_15940	COG1104	cysteine desulfurase activity
N8A75_15945	COG1114	Component of the transport system for branched-chain amino acids
N8A75_15950	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
N8A75_15955	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N8A75_15960	COG1309	transcriptional regulator
N8A75_15965	COG1956	GAF domain-containing protein
N8A75_15970	COG2203	Gaf domain
N8A75_15970	COG2199	diguanylate cyclase activity
N8A75_15975	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N8A75_15985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N8A75_15990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N8A75_15995	COG0454	-acetyltransferase
N8A75_16000	COG0517	IMP dehydrogenase activity
N8A75_16005	COG0123	including yeast histone deacetylase and acetoin utilization protein
N8A75_16010	COG1360	Flagellar Motor Protein
N8A75_16015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N8A75_16020	COG1609	Transcriptional regulator
N8A75_16025	COG1605	Chorismate mutase
N8A75_16025	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
N8A75_16030	COG3118	belongs to the thioredoxin family
N8A75_16035	COG4980	gas vesicle protein
N8A75_16040	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N8A75_16045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N8A75_16050	COG1674	ftsk spoiiie
N8A75_16055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N8A75_16060	COG4848	Belongs to the UPF0354 family
N8A75_16065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8A75_16080	COG1363	Peptidase, m42
N8A75_16085	COG5584	Small secreted protein
N8A75_16090	COG0281	malic enzyme
N8A75_16095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8A75_16100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N8A75_16110	COG0510	thiamine kinase activity
N8A75_16115	COG1523	belongs to the glycosyl hydrolase 13 family
N8A75_16120	COG1597	lipid kinase activity
N8A75_16130	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N8A75_16135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N8A75_16140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N8A75_16145	COG2252	PERMEase
N8A75_16150	COG4473	ABC transporter
N8A75_16155	COG1131	(ABC) transporter
N8A75_16160	COG1349	DNA-binding transcription factor activity
N8A75_16165	COG1187	pseudouridine synthase activity
N8A75_16170	COG2244	polysaccharide biosynthetic process
N8A75_16175	COG2081	HI0933 family
N8A75_16180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N8A75_16190	COG5578	integral membrane protein
N8A75_16195	COG0673	inositol 2-dehydrogenase activity
N8A75_16200	COG1653	transport
N8A75_16205	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N8A75_16210	COG4209	transmembrane transport
N8A75_16215	COG2207	Transcriptional regulator
N8A75_16220	COG1653	transport
N8A75_16225	COG0395	ABC-type sugar transport system, permease component
N8A75_16230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N8A75_16235	COG2124	cytochrome p450
N8A75_16240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N8A75_16250	COG0156	8-amino-7-oxononanoate synthase activity
N8A75_16255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N8A75_16265	COG1073	alpha beta
N8A75_16270	COG1609	Transcriptional regulator
N8A75_16275	COG1653	transport
N8A75_16280	COG1175	transmembrane transport
N8A75_16285	COG0395	ABC-type sugar transport system, permease component
N8A75_16290	COG1486	melibiose metabolic process
N8A75_16295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N8A75_16300	COG0495	leucyl-tRNA aminoacylation
N8A75_16310	COG2202	Pas domain
N8A75_16310	COG1366	Belongs to the anti-sigma-factor antagonist family
N8A75_16315	COG2814	Major facilitator Superfamily
N8A75_16320	COG2433	Pfam Transposase IS66
N8A75_16325	COG0577	efflux transmembrane transporter activity
N8A75_16330	COG1136	(ABC) transporter
N8A75_16335	COG2205	protein histidine kinase activity
N8A75_16340	COG0745	RESPONSE REGULATOR receiver
N8A75_16345	COG0577	efflux transmembrane transporter activity
N8A75_16350	COG1136	(ABC) transporter
N8A75_16365	COG1131	(ABC) transporter
N8A75_16370	COG1725	Transcriptional regulator
N8A75_16385	COG1242	4 iron, 4 sulfur cluster binding
N8A75_16390	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
N8A75_16400	COG2267	carboxylic ester hydrolase activity
N8A75_16405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N8A75_16410	COG1113	amino acid transport
N8A75_16415	COG0367	asparagine synthase
N8A75_16420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N8A75_16425	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N8A75_16435	COG1506	peptidase
N8A75_16440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N8A75_16445	COG1116	anion transmembrane transporter activity
N8A75_16450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N8A75_16455	COG0494	nUDIX hydrolase
N8A75_16460	COG4824	toxin secretion phage lysis holin
N8A75_16465	COG0783	Belongs to the Dps family
N8A75_16480	COG1854	S-ribosylhomocysteine lyase activity
N8A75_16485	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N8A75_16490	COG0288	reversible hydration of carbon dioxide
N8A75_16495	COG0254	rRNA binding
N8A75_16500	COG1271	oxidase subunit
N8A75_16505	COG1294	oxidase, subunit
N8A75_16515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N8A75_16520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N8A75_16520	COG1321	iron dependent repressor
N8A75_16525	COG1121	(ABC) transporter
N8A75_16530	COG0803	Belongs to the bacterial solute-binding protein 9 family
N8A75_16535	COG4948	Mandelate Racemase Muconate Lactonizing
N8A75_16540	COG0318	PFAM AMP-dependent synthetase and ligase
N8A75_16545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
N8A75_16550	COG0596	Alpha beta hydrolase
N8A75_16555	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N8A75_16560	COG1169	isochorismate synthase
N8A75_16565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N8A75_16570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N8A75_16575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N8A75_16580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N8A75_16585	COG0438	transferase activity, transferring glycosyl groups
N8A75_16595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N8A75_16600	COG0438	transferase activity, transferring glycosyl groups
N8A75_16605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N8A75_16610	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
N8A75_16615	COG0058	SHG alpha-glucan phosphorylase activity
N8A75_16620	COG0297	glycogen (starch) synthase activity
N8A75_16630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N8A75_16635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N8A75_16760	COG3859	Proton-coupled thiamine transporter YuaJ
N8A75_16765	COG1247	-acetyltransferase
N8A75_16770	COG2268	Band 7 protein
N8A75_16775	COG1585	Membrane protein implicated in regulation of membrane protease activity
N8A75_16780	COG2318	DinB family
N8A75_16790	COG1454	alcohol dehydrogenase
N8A75_16795	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_16800	COG1510	regulation of RNA biosynthetic process
N8A75_16810	COG0569	domain protein
N8A75_16815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N8A75_16820	COG4682	membrane
N8A75_16825	COG1705	Flagellar rod assembly protein muramidase FlgJ
N8A75_16830	COG0477	Major facilitator Superfamily
N8A75_16835	COG5553	Cysteine dioxygenase type I
N8A75_16845	COG1968	undecaprenyl-diphosphatase activity
N8A75_16850	COG0628	permease
N8A75_16855	COG0673	inositol 2-dehydrogenase activity
N8A75_16860	COG4806	L-rhamnose isomerase
N8A75_16865	COG3254	rhamnose metabolic process
N8A75_16870	COG1070	Carbohydrate kinase
N8A75_16875	COG1349	DNA-binding transcription factor activity
N8A75_16880	COG3347	Dehydrogenase
N8A75_16880	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_16885	COG0840	transmembrane signaling receptor activity
N8A75_16890	COG0840	transmembrane signaling receptor activity
N8A75_16895	COG0840	transmembrane signaling receptor activity
N8A75_16900	COG0840	transmembrane signaling receptor activity
N8A75_16920	COG0432	Pfam Uncharacterised protein family UPF0047
N8A75_16930	COG0366	Alpha amylase catalytic
N8A75_16935	COG1253	flavin adenine dinucleotide binding
N8A75_16940	COG2738	Putative neutral zinc metallopeptidase
N8A75_16955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N8A75_16970	COG0166	Belongs to the GPI family
N8A75_16975	COG1979	alcohol dehydrogenase
N8A75_16980	COG1979	alcohol dehydrogenase
N8A75_16985	COG2155	Conserved Protein
N8A75_16990	COG1098	S1 RNA binding domain
N8A75_16995	COG0436	Aminotransferase
N8A75_17000	COG1522	sequence-specific DNA binding
N8A75_17005	COG2267	carboxylic ester hydrolase activity
N8A75_17015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
N8A75_17020	COG2205	protein histidine kinase activity
N8A75_17030	COG5018	Exonuclease
N8A75_17040	COG2814	Major facilitator Superfamily
N8A75_17045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N8A75_17050	COG3011	Protein conserved in bacteria
N8A75_17060	COG3290	protein histidine kinase activity
N8A75_17065	COG4565	transcriptional regulatory protein
N8A75_17070	COG1744	ABC transporter substrate-binding protein PnrA-like
N8A75_17075	COG3845	ABC transporter
N8A75_17080	COG4603	Belongs to the binding-protein-dependent transport system permease family
N8A75_17085	COG1079	Belongs to the binding-protein-dependent transport system permease family
N8A75_17090	COG3493	citrate carrier protein
N8A75_17100	COG2111	Na H antiporter
N8A75_17100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N8A75_17105	COG2111	Na H antiporter
N8A75_17110	COG1006	Multisubunit Na H antiporter MnhC subunit
N8A75_17115	COG0651	ATP synthesis coupled electron transport
N8A75_17120	COG1863	multisubunit Na H antiporter MnhE subunit
N8A75_17125	COG2212	antiporter activity
N8A75_17130	COG1320	monovalent cation:proton antiporter activity
N8A75_17135	COG2050	protein possibly involved in aromatic compounds catabolism
N8A75_17140	COG2197	response regulator
N8A75_17145	COG4585	Histidine kinase
N8A75_17155	COG0142	geranyltranstransferase activity
N8A75_17175	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N8A75_17180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N8A75_17185	COG1335	isochorismatase
N8A75_17190	COG5506	Protein of unknown function (DUF1694)
N8A75_17205	COG0628	permease
N8A75_17220	COG1418	mRNA catabolic process
N8A75_17225	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_17235	COG1511	domain protein
N8A75_17240	COG0433	COG0433 Predicted ATPase
N8A75_17240	COG1674	ftsk spoiiie
N8A75_17245	COG4499	WXG100 protein secretion system (Wss), protein YukC
N8A75_17250	COG5417	Belongs to the EsaB family
N8A75_17255	COG4842	Belongs to the WXG100 family
N8A75_17260	COG2508	Transcriptional regulator
N8A75_17260	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N8A75_17265	COG0686	Belongs to the AlaDH PNT family
N8A75_17270	COG5634	Uncharacterized conserved protein (DUF2278)
N8A75_17275	COG3251	PFAM MbtH domain protein
N8A75_17280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8A75_17285	COG1535	isochorismatase
N8A75_17285	COG3433	isochorismatase activity
N8A75_17290	COG1021	2,3-dihydroxybenzoate-AMP ligase
N8A75_17295	COG1169	isochorismate synthase
N8A75_17300	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_17305	COG2819	hydrolase of the alpha beta superfamily
N8A75_17310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N8A75_17315	COG1268	BioY protein
N8A75_17320	COG2056	Na+-H+ antiporter family
N8A75_17325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N8A75_17330	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
N8A75_17335	COG3584	3D domain protein
N8A75_17350	COG1252	NADH dehydrogenase
N8A75_17355	COG0492	ferredoxin-NADP+ reductase activity
N8A75_17365	COG0516	GMP reductase activity
N8A75_17370	COG2808	Putative FMN-binding domain
N8A75_17375	COG0456	acetyltransferase
N8A75_17380	COG0316	Belongs to the HesB IscA family
N8A75_17385	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N8A75_17390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N8A75_17395	COG4844	belongs to the
N8A75_17400	COG1252	NADH dehydrogenase
N8A75_17405	COG4837	Protein of unknown function (DUF1462)
N8A75_17410	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N8A75_17415	COG4946	Tricorn protease homolog
N8A75_17415	COG1506	peptidase
N8A75_17415	COG0823	Involved in the tonB-independent uptake of proteins
N8A75_17420	COG0083	homoserine kinase activity
N8A75_17425	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N8A75_17430	COG0460	homoserine dehydrogenase
N8A75_17435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N8A75_17440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N8A75_17445	COG0647	UMP catabolic process
N8A75_17450	COG2445	Protein of unknown function DUF86
N8A75_17455	COG4470	Protein conserved in bacteria
N8A75_17465	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N8A75_17470	COG0739	heme binding
N8A75_17480	COG3377	Domain of unknown function (DUF1805)
N8A75_17485	COG0737	Belongs to the 5'-nucleotidase family
N8A75_17490	COG0730	response to heat
N8A75_17495	COG1801	Protein of unknown function DUF72
N8A75_17505	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N8A75_17510	COG2508	Transcriptional regulator
N8A75_17515	COG2233	PERMEase
N8A75_17520	COG2233	PERMEase
N8A75_17525	COG3195	allantoin biosynthetic process
N8A75_17525	COG3648	Uricase
N8A75_17530	COG2351	hydroxyisourate hydrolase activity
N8A75_17540	COG2080	2 iron, 2 sulfur cluster binding
N8A75_17545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N8A75_17550	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
N8A75_17555	COG2068	MobA-Related Protein
N8A75_17560	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N8A75_17565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N8A75_17570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N8A75_17580	COG2356	endonuclease I
N8A75_17585	COG3842	ATPase activity
N8A75_17590	COG2188	Transcriptional regulator
N8A75_17595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8A75_17600	COG0395	ABC-type sugar transport system, permease component
N8A75_17605	COG1175	transmembrane transport
N8A75_17610	COG1653	transport
N8A75_17615	COG2222	sugar isomerase
N8A75_17620	COG0322	excinuclease ABC activity
N8A75_17625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N8A75_17640	COG0346	lactoylglutathione lyase activity
N8A75_17645	COG0640	Transcriptional regulator
N8A75_17650	COG0719	Fe-S assembly protein
N8A75_17655	COG0822	iron-sulfur transferase activity
N8A75_17660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N8A75_17665	COG0719	Fe-S assembly protein
N8A75_17670	COG0396	ATPase activity
N8A75_17680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N8A75_17685	COG1464	Belongs to the NlpA lipoprotein family
N8A75_17690	COG2011	ABC-type metal ion transport system permease component
N8A75_17695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N8A75_17705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8A75_17710	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N8A75_17720	COG0509	glycine decarboxylation via glycine cleavage system
N8A75_17725	COG1393	Belongs to the ArsC family
N8A75_17730	COG1960	acyl-CoA dehydrogenase activity
N8A75_17735	COG0183	Belongs to the thiolase family
N8A75_17740	COG1024	Enoyl-CoA hydratase
N8A75_17740	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8A75_17760	COG5577	PFAM Coat F domain
N8A75_17765	COG1846	Transcriptional regulator
N8A75_17770	COG0477	Major facilitator Superfamily
N8A75_17775	COG1942	4-Oxalocrotonate Tautomerase
N8A75_17780	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_17785	COG0583	DNA-binding transcription factor activity
N8A75_17795	COG1120	ATPase activity
N8A75_17810	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_17815	COG0783	Belongs to the Dps family
N8A75_17820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N8A75_17825	COG0745	RESPONSE REGULATOR receiver
N8A75_17830	COG2770	Histidine kinase
N8A75_17830	COG2205	protein histidine kinase activity
N8A75_17840	COG1309	transcriptional regulator
N8A75_17845	COG0114	fumarate hydratase activity
N8A75_17855	COG0697	spore germination
N8A75_17860	COG0814	amino acid
N8A75_17870	COG2197	response regulator
N8A75_17875	COG4585	Histidine kinase
N8A75_17880	COG4758	membrane
N8A75_17885	COG3595	metallopeptidase activity
N8A75_17890	COG1842	Phage shock protein A
N8A75_17895	COG4758	membrane
N8A75_17900	COG2814	Major facilitator Superfamily
N8A75_17905	COG2096	Adenosyltransferase
N8A75_17910	COG1120	ATPase activity
N8A75_17915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8A75_17920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N8A75_17925	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_17930	COG3386	PFAM SMP-30 Gluconolaconase
N8A75_17935	COG2205	protein histidine kinase activity
N8A75_17940	COG0745	RESPONSE REGULATOR receiver
N8A75_17950	COG1191	sigma factor activity
N8A75_17960	COG2140	Oxalate decarboxylase
N8A75_17970	COG0577	efflux transmembrane transporter activity
N8A75_17975	COG1136	(ABC) transporter
N8A75_17980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N8A75_17985	COG1120	ATPase activity
N8A75_17990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8A75_17995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8A75_18000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N8A75_18005	COG0531	amino acid
N8A75_18015	COG1988	membrane-bound metal-dependent
N8A75_18020	COG1368	sulfuric ester hydrolase activity
N8A75_18025	COG1910	domain protein
N8A75_18030	COG0725	ABC transporter, periplasmic molybdate-binding protein
N8A75_18035	COG4149	molybdate abc transporter
N8A75_18040	COG0656	L-ascorbic acid biosynthetic process
N8A75_18050	COG0025	NhaP-type Na H and K H
N8A75_18055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N8A75_18060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N8A75_18065	COG3973	AAA domain
N8A75_18075	COG2860	membrane
N8A75_18080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
N8A75_18085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N8A75_18090	COG2217	Heavy metal translocating P-type atpase
N8A75_18095	COG2217	Heavy metal translocating P-type atpase
N8A75_18100	COG2608	mercury ion transmembrane transporter activity
N8A75_18105	COG1937	Protein conserved in bacteria
N8A75_18110	COG0673	inositol 2-dehydrogenase activity
N8A75_18115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N8A75_18120	COG1289	transmembrane transporter activity
N8A75_18130	COG2076	Multidrug Resistance protein
N8A75_18135	COG1309	transcriptional regulator
N8A75_18140	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_18150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N8A75_18155	COG0557	exoribonuclease II activity
N8A75_18160	COG1647	Serine aminopeptidase, S33
N8A75_18165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N8A75_18170	COG0596	Alpha beta hydrolase
N8A75_18175	COG1476	TRANSCRIPTIONal
N8A75_18180	COG1396	sequence-specific DNA binding
N8A75_18185	COG1396	sequence-specific DNA binding
N8A75_18190	COG1733	regulation of RNA biosynthetic process
N8A75_18195	COG0840	transmembrane signaling receptor activity
N8A75_18200	COG1174	glycine betaine transport
N8A75_18205	COG1732	Glycine betaine
N8A75_18210	COG1174	glycine betaine transport
N8A75_18215	COG1125	glycine betaine transport
N8A75_18215	COG0517	IMP dehydrogenase activity
N8A75_18220	COG1510	regulation of RNA biosynthetic process
N8A75_18225	COG1174	glycine betaine transport
N8A75_18230	COG1732	Glycine betaine
N8A75_18235	COG1174	glycine betaine transport
N8A75_18240	COG0517	IMP dehydrogenase activity
N8A75_18240	COG1125	glycine betaine transport
N8A75_18245	COG1510	regulation of RNA biosynthetic process
N8A75_18250	COG2095	MarC family integral membrane protein
N8A75_18260	COG3064	Membrane
N8A75_18265	COG4640	response to antibiotic
N8A75_18270	COG0456	acetyltransferase
N8A75_18275	COG0148	phosphopyruvate hydratase activity
N8A75_18280	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N8A75_18285	COG0149	triose-phosphate isomerase activity
N8A75_18290	COG0126	phosphoglycerate kinase activity
N8A75_18295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N8A75_18300	COG2390	Transcriptional regulator
N8A75_18305	COG2814	Major facilitator Superfamily
N8A75_18310	COG1609	Transcriptional regulator
N8A75_18315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8A75_18320	COG0583	DNA-binding transcription factor activity
N8A75_18325	COG0697	spore germination
N8A75_18330	COG1113	amino acid transport
N8A75_18335	COG3858	chitin binding
N8A75_18340	COG1556	Lactate utilization protein
N8A75_18345	COG1139	Iron-sulfur cluster binding protein
N8A75_18350	COG0247	lactate metabolic process
N8A75_18365	COG2197	response regulator
N8A75_18370	COG4585	Histidine kinase
N8A75_18375	COG0842	Transport permease protein
N8A75_18380	COG1131	(ABC) transporter
N8A75_18390	COG0596	Alpha beta hydrolase
N8A75_18395	COG2208	phosphoserine phosphatase activity
N8A75_18400	COG3867	Arabinogalactan endo-beta-1,4-galactanase
N8A75_18405	COG1874	Beta-galactosidase
N8A75_18410	COG3833	ABC-type maltose transport systems, permease component
N8A75_18415	COG1175	transmembrane transport
N8A75_18420	COG2182	Extracellular solute-binding protein
N8A75_18425	COG1609	Transcriptional regulator
N8A75_18430	COG2186	Transcriptional regulator
N8A75_18435	COG1620	l-lactate permease
N8A75_18440	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N8A75_18450	COG5039	Polysaccharide pyruvyl transferase
N8A75_18455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N8A75_18460	COG0110	maltose O-acetyltransferase activity
N8A75_18465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N8A75_18470	COG2244	polysaccharide biosynthetic process
N8A75_18475	COG1216	Glycosyl transferase, family 2
N8A75_18480	COG5039	Polysaccharide pyruvyl transferase
N8A75_18485	COG1216	Glycosyl transferase, family 2
N8A75_18495	COG0438	transferase activity, transferring glycosyl groups
N8A75_18500	COG1215	transferase activity, transferring glycosyl groups
N8A75_18505	COG0438	transferase activity, transferring glycosyl groups
N8A75_18510	COG1086	Polysaccharide biosynthesis protein
N8A75_18515	COG0489	protein tyrosine kinase activity
N8A75_18520	COG3944	biosynthesis protein
N8A75_18525	COG1396	sequence-specific DNA binding
N8A75_18530	COG2272	Belongs to the type-B carboxylesterase lipase family
N8A75_18540	COG3479	Phenolic acid decarboxylase
N8A75_18550	COG1794	racemase activity, acting on amino acids and derivatives
N8A75_18555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N8A75_18560	COG1621	beta-fructofuranosidase activity
N8A75_18565	COG1621	beta-fructofuranosidase activity
N8A75_18570	COG0531	amino acid
N8A75_18575	COG1309	transcriptional regulator
N8A75_18580	COG2076	Multidrug Resistance protein
N8A75_18585	COG2076	Multidrug Resistance protein
N8A75_18600	COG0740	serine-type endopeptidase activity
N8A75_18605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N8A75_18610	COG0366	Alpha amylase catalytic
N8A75_18615	COG1554	hydrolase, family 65, central catalytic
N8A75_18620	COG5521	maltodextrose utilization protein MalA
N8A75_18625	COG3833	ABC-type maltose transport systems, permease component
N8A75_18630	COG1175	transmembrane transport
N8A75_18635	COG2182	Extracellular solute-binding protein
N8A75_18645	COG1609	Transcriptional regulator
N8A75_18650	COG1611	Belongs to the LOG family
N8A75_18655	COG1694	Mazg nucleotide pyrophosphohydrolase
N8A75_18660	COG0659	secondary active sulfate transmembrane transporter activity
N8A75_18665	COG0288	reversible hydration of carbon dioxide
N8A75_18670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N8A75_18675	COG0577	efflux transmembrane transporter activity
N8A75_18680	COG1136	(ABC) transporter
N8A75_18685	COG5002	protein histidine kinase activity
N8A75_18690	COG0745	RESPONSE REGULATOR receiver
N8A75_18700	COG2162	N-hydroxyarylamine O-acetyltransferase activity
N8A75_18705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8A75_18710	COG1481	regulation of sporulation
N8A75_18715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N8A75_18720	COG1660	Displays ATPase and GTPase activities
N8A75_18725	COG1051	belongs to the nudix hydrolase family
N8A75_18730	COG0492	ferredoxin-NADP+ reductase activity
N8A75_18735	COG3883	PFAM NLP P60 protein
N8A75_18735	COG0791	NLP P60 protein
N8A75_18740	COG0457	Tetratricopeptide repeat
N8A75_18745	COG1132	(ABC) transporter
N8A75_18765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N8A75_18765	COG0140	phosphoribosyl-ATP diphosphatase activity
N8A75_18770	COG0107	imidazoleglycerol-phosphate synthase activity
N8A75_18775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N8A75_18780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N8A75_18785	COG0131	Imidazoleglycerol-phosphate dehydratase
N8A75_18790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N8A75_18795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N8A75_18800	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
N8A75_18805	COG4990	cell redox homeostasis
N8A75_18810	COG5297	Belongs to the glycosyl hydrolase family 6
N8A75_18815	COG0110	maltose O-acetyltransferase activity
N8A75_18820	COG0546	phosphoglycolate phosphatase activity
N8A75_18825	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
N8A75_18830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N8A75_18835	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
N8A75_18840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N8A75_18845	COG0363	glucosamine-6-phosphate deaminase activity
N8A75_18850	COG2188	Transcriptional regulator
N8A75_18855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N8A75_18860	COG1846	Transcriptional regulator
N8A75_18865	COG2124	cytochrome p450
N8A75_18875	COG1846	Transcriptional regulator
N8A75_18880	COG2814	Major facilitator Superfamily
N8A75_18885	COG1950	PFAM Membrane protein of
N8A75_18890	COG1983	PspC domain protein
N8A75_18895	COG3595	metallopeptidase activity
N8A75_18910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N8A75_18915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N8A75_18920	COG0556	nucleotide-excision repair
N8A75_18925	COG4897	Protein conserved in bacteria
N8A75_18930	COG0574	Belongs to the PEP-utilizing enzyme family
N8A75_18930	COG3848	Pyruvate phosphate dikinase
N8A75_18935	COG1309	transcriptional regulator
N8A75_18940	COG2814	Major facilitator Superfamily
N8A75_18945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N8A75_18955	COG0793	Belongs to the peptidase S41A family
N8A75_18955	COG3409	Peptidoglycan-binding domain 1 protein
N8A75_18960	COG2177	Part of the ABC transporter FtsEX involved in
N8A75_18965	COG2884	Cell division ATP-binding protein ftsE
N8A75_18970	COG2010	Cytochrome c
N8A75_18975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N8A75_18985	COG0653	protein targeting
N8A75_18990	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N8A75_19005	COG1516	flagellar protein fliS
N8A75_19010	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N8A75_19015	COG1334	flagellar protein FlaG
N8A75_19020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N8A75_19025	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N8A75_19030	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
N8A75_19040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N8A75_19045	COG1256	bacterial-type flagellum assembly
N8A75_19045	COG4786	Flagellar basal body rod
N8A75_19050	COG3418	PFAM FlgN family protein
N8A75_19055	COG2747	anti-sigma28 factor FlgM
N8A75_19065	COG1040	competence protein
N8A75_19075	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
N8A75_19080	COG1307	EDD domain protein, DegV family
N8A75_19085	COG2197	response regulator
N8A75_19090	COG4585	Histidine kinase
N8A75_19095	COG1739	Uncharacterized protein family UPF0029
N8A75_19100	COG1316	TRANSCRIPTIONal
N8A75_19105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N8A75_19110	COG0438	transferase activity, transferring glycosyl groups
N8A75_19115	COG1215	transferase activity, transferring glycosyl groups
N8A75_19120	COG3206	protein involved in exopolysaccharide biosynthesis
N8A75_19125	COG3307	-O-antigen
N8A75_19130	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N8A75_19135	COG0297	glycogen (starch) synthase activity
N8A75_19135	COG0438	transferase activity, transferring glycosyl groups
N8A75_19140	COG2244	polysaccharide biosynthetic process
N8A75_19150	COG0860	N-Acetylmuramoyl-L-alanine amidase
N8A75_19150	COG2247	cell wall binding repeat
N8A75_19155	COG2385	sporulation resulting in formation of a cellular spore
N8A75_19155	COG2247	cell wall binding repeat
N8A75_19165	COG1316	TRANSCRIPTIONal
N8A75_19170	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N8A75_19175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N8A75_19190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N8A75_19190	COG1215	transferase activity, transferring glycosyl groups
N8A75_19195	COG0463	Glycosyl transferase, family 2
N8A75_19220	COG1134	teichoic acid transport
N8A75_19225	COG1682	transport, permease protein
N8A75_19230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N8A75_19235	COG0438	transferase activity, transferring glycosyl groups
N8A75_19240	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
N8A75_19245	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
N8A75_19250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N8A75_19260	COG4193	domain, Protein
N8A75_19265	COG1482	cell wall glycoprotein biosynthetic process
N8A75_19270	COG0697	spore germination
N8A75_19275	COG0814	amino acid
N8A75_19285	COG2814	Major facilitator Superfamily
N8A75_19290	COG1316	TRANSCRIPTIONal
N8A75_19295	COG0561	phosphatase activity
N8A75_19300	COG0791	NLP P60 protein
N8A75_19310	COG2843	Capsule synthesis protein
N8A75_19320	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N8A75_19325	COG1609	Transcriptional regulator
N8A75_19330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8A75_19335	COG1869	D-ribose catabolic process
N8A75_19340	COG1129	ABC transporter
N8A75_19345	COG1172	Belongs to the binding-protein-dependent transport system permease family
N8A75_19350	COG1879	ABC-type sugar transport system periplasmic component
N8A75_19355	COG3103	Sh3 type 3 domain protein
N8A75_19365	COG2249	NAD(P)H dehydrogenase (quinone) activity
N8A75_19370	COG3527	Alpha-acetolactate decarboxylase
N8A75_19375	COG0028	Belongs to the TPP enzyme family
N8A75_19380	COG0583	DNA-binding transcription factor activity
N8A75_19385	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N8A75_19400	COG5337	Spore coat protein CotH
N8A75_19410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N8A75_19420	COG0405	Gamma-glutamyltransferase
N8A75_19425	COG1522	sequence-specific DNA binding
N8A75_19430	COG2059	Chromate
N8A75_19435	COG2059	Chromate
N8A75_19445	COG0655	NAD(P)H dehydrogenase (quinone) activity
N8A75_19450	COG0583	DNA-binding transcription factor activity
N8A75_19500	COG3878	Protein conserved in bacteria
N8A75_19505	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N8A75_19510	COG4464	protein tyrosine phosphatase activity
N8A75_19515	COG0489	protein tyrosine kinase activity
N8A75_19520	COG3944	biosynthesis protein
N8A75_19530	COG4715	Zinc finger, swim domain protein
N8A75_19535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N8A75_19540	COG0561	phosphatase activity
N8A75_19545	COG1349	DNA-binding transcription factor activity
N8A75_19550	COG0629	single-stranded DNA binding
N8A75_19575	COG0745	RESPONSE REGULATOR receiver
N8A75_19575	COG2972	Histidine kinase
N8A75_19580	COG1970	mechanosensitive ion channel activity
N8A75_19585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N8A75_19590	COG0457	Tetratricopeptide repeat
N8A75_19595	COG4786	Flagellar basal body rod
N8A75_19600	COG4786	Flagellar basal body rod
N8A75_19605	COG1077	Cell shape determining protein MreB Mrl
N8A75_19610	COG1609	Transcriptional regulator
N8A75_19620	COG1846	Transcriptional regulator
N8A75_19625	COG2814	Major facilitator Superfamily
N8A75_19630	COG3420	alginic acid biosynthetic process
N8A75_19635	COG1953	Uracil, thiamine, allantoin
N8A75_19640	COG0477	Major facilitator Superfamily
N8A75_19645	COG1335	isochorismatase
N8A75_19655	COG0004	ammonium transporteR
N8A75_19660	COG0347	Belongs to the P(II) protein family
N8A75_19665	COG0671	phosphoesterase, PA-phosphatase related
N8A75_19675	COG0739	heme binding
N8A75_19680	COG1247	-acetyltransferase
N8A75_19690	COG2089	acid synthase
N8A75_19700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N8A75_19705	COG0789	Transcriptional regulator
N8A75_19715	COG2910	NAD(P)H-binding
N8A75_19720	COG1959	2 iron, 2 sulfur cluster binding
N8A75_19725	COG0804	urea catabolic process
N8A75_19730	COG0832	Belongs to the urease beta subunit family
N8A75_19735	COG0831	urea catabolic process
N8A75_19750	COG3237	CsbD-like
N8A75_19755	COG1994	Peptidase M50
N8A75_19760	COG0457	Tetratricopeptide repeat
N8A75_19765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N8A75_19770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N8A75_19780	COG2304	oxidoreductase activity
N8A75_19790	COG2304	oxidoreductase activity
N8A75_19795	COG2385	sporulation resulting in formation of a cellular spore
N8A75_19800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N8A75_19810	COG4836	Membrane
N8A75_19820	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N8A75_19825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N8A75_19830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N8A75_19835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N8A75_19840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N8A75_19845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N8A75_19855	COG0356	it plays a direct role in the translocation of protons across the membrane
N8A75_19865	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N8A75_19870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N8A75_19875	COG4475	Protein of unknown function (DUF436)
N8A75_19880	COG0698	ribose 5-phosphate isomerase
N8A75_19885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N8A75_19890	COG1971	Probably functions as a manganese efflux pump
N8A75_19895	COG0009	L-threonylcarbamoyladenylate synthase
N8A75_19900	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N8A75_19920	COG2890	protein-(glutamine-N5) methyltransferase activity
N8A75_19925	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N8A75_19930	COG0346	lactoylglutathione lyase activity
N8A75_19935	COG0789	Transcriptional regulator
N8A75_19940	COG0679	Auxin Efflux Carrier
N8A75_19945	COG0281	malic enzyme
N8A75_19950	COG1435	thymidine kinase activity
N8A75_19960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N8A75_19970	COG1494	fructose-1,6-bisphosphatase
N8A75_19975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N8A75_19980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N8A75_19985	COG0191	fructose-bisphosphate aldolase activity
N8A75_19990	COG2204	response regulator
N8A75_19995	COG4821	SIS domain
N8A75_20000	COG0504	CTP synthase activity
N8A75_20005	COG3343	RNA polymerase activity
N8A75_20010	COG1960	acyl-CoA dehydrogenase activity
N8A75_20015	COG2181	nitrate reductase activity
N8A75_20015	COG0247	lactate metabolic process
N8A75_20020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N8A75_20025	COG4294	response to UV
N8A75_20035	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N8A75_20040	COG1132	(ABC) transporter
N8A75_20045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N8A75_20055	COG2181	nitrate reductase activity
N8A75_20060	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
N8A75_20065	COG1140	nitrate reductase beta subunit
N8A75_20070	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
N8A75_20075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N8A75_20085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N8A75_20090	COG2223	nitrite transmembrane transporter activity
N8A75_20095	COG0018	arginyl-trna synthetase
N8A75_20100	COG4506	Protein conserved in bacteria
N8A75_20115	COG0535	radical SAM domain protein
N8A75_20125	COG1131	(ABC) transporter
N8A75_20130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N8A75_20135	COG0612	Peptidase, M16
N8A75_20140	COG0612	Peptidase, M16
N8A75_20150	COG3391	amine dehydrogenase activity
N8A75_20155	COG3391	amine dehydrogenase activity
N8A75_20160	COG0457	Tetratricopeptide repeat
N8A75_20175	COG0010	Belongs to the arginase family
N8A75_20180	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N8A75_20185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N8A75_20200	COG1994	Peptidase M50
N8A75_20205	COG1942	4-Oxalocrotonate Tautomerase
N8A75_20210	COG1846	Transcriptional regulator
N8A75_20215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N8A75_20220	COG0477	Major facilitator Superfamily
N8A75_20225	COG1959	2 iron, 2 sulfur cluster binding
N8A75_20230	COG3465	dGTPase activity
N8A75_20235	COG1078	dGTPase activity
N8A75_20240	COG4844	belongs to the
N8A75_20250	COG0697	spore germination
N8A75_20255	COG0095	Lipoate-protein ligase
N8A75_20260	COG0583	DNA-binding transcription factor activity
N8A75_20265	COG0280	phosphate acetyltransferase
N8A75_20270	COG3253	May function as heme-dependent peroxidase
N8A75_20275	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_20280	COG0436	Aminotransferase
N8A75_20285	COG2814	Major facilitator Superfamily
N8A75_20290	COG0151	Belongs to the GarS family
N8A75_20295	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_20300	COG1917	Cupin 2, conserved barrel domain protein
N8A75_20305	COG0077	Prephenate dehydratase
N8A75_20310	COG2814	Major facilitator Superfamily
N8A75_20315	COG0833	amino acid
N8A75_20320	COG4187	Peptidase family M20/M25/M40
N8A75_20325	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_20330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N8A75_20340	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N8A75_20345	COG1091	dTDP-4-dehydrorhamnose reductase activity
N8A75_20350	COG1088	dTDP-glucose 4,6-dehydratase activity
N8A75_20355	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
N8A75_20360	COG3980	spore coat polysaccharide biosynthesis protein
N8A75_20365	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
N8A75_20370	COG2089	acid synthase
N8A75_20375	COG0456	acetyltransferase
N8A75_20380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N8A75_20385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N8A75_20390	COG0463	Glycosyl transferase, family 2
N8A75_20400	COG2363	Small membrane protein
N8A75_20405	COG2233	PERMEase
N8A75_20415	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_20420	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N8A75_20425	COG1216	Glycosyl transferase, family 2
N8A75_20440	COG1695	Transcriptional regulator
N8A75_20445	COG0351	phosphomethylpyrimidine kinase
N8A75_20455	COG1621	beta-fructofuranosidase activity
N8A75_20460	COG1263	PTS System
N8A75_20460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8A75_20465	COG2116	formate transmembrane transporter activity
N8A75_20470	COG3711	transcriptional antiterminator
N8A75_20480	COG1404	Belongs to the peptidase S8 family
N8A75_20485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8A75_20490	COG0778	Nitroreductase
N8A75_20495	COG0772	Belongs to the SEDS family
N8A75_20510	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N8A75_20515	COG1845	cytochrome c oxidase, subunit III
N8A75_20520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N8A75_20525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N8A75_20530	COG2261	transglycosylase associated protein
N8A75_20535	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
N8A75_20540	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
N8A75_20545	COG2246	polysaccharide biosynthetic process
N8A75_20550	COG1309	transcriptional regulator
N8A75_20560	COG3162	membrane
N8A75_20565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8A75_20570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N8A75_20575	COG2837	iron assimilation
N8A75_20580	COG2822	iron ion transport
N8A75_20585	COG0672	)-iron permease
N8A75_20590	COG0352	thiamine-phosphate diphosphorylase activity
N8A75_20595	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
N8A75_20600	COG0583	DNA-binding transcription factor activity
N8A75_20605	COG1380	Effector of murein hydrolase LrgA
N8A75_20610	COG1346	cytolysis
N8A75_20615	COG2814	Major facilitator Superfamily
N8A75_20620	COG4895	conserved protein (DUF2196)
N8A75_20625	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N8A75_20630	COG0346	lactoylglutathione lyase activity
N8A75_20640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N8A75_20645	COG1404	Belongs to the peptidase S8 family
N8A75_20650	COG1263	PTS System
N8A75_20650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8A75_20655	COG3711	transcriptional antiterminator
N8A75_20660	COG1442	glycosyl transferase family 8
N8A75_20665	COG5522	Integral membrane protein (intg_mem_TP0381)
N8A75_20670	COG1846	Transcriptional regulator
N8A75_20675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N8A75_20680	COG2234	aminopeptidase activity
N8A75_20695	COG2814	Major facilitator Superfamily
N8A75_20700	COG2357	RelA SpoT domain protein
N8A75_20705	COG1575	Belongs to the MenA family. Type 1 subfamily
N8A75_20720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8A75_20725	COG1696	Membrane protein involved in D-alanine export
N8A75_20730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N8A75_20735	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
N8A75_20740	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
N8A75_20745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N8A75_20750	COG1486	melibiose metabolic process
N8A75_20755	COG1447	Phosphotransferase system cellobiose-specific component IIA
N8A75_20760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N8A75_20765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N8A75_20770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8A75_20770	COG3711	transcriptional antiterminator
N8A75_20780	COG2094	Belongs to the DNA glycosylase MPG family
N8A75_20785	COG0753	catalase activity
N8A75_20790	COG2814	Major facilitator Superfamily
N8A75_20795	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N8A75_20800	COG1131	(ABC) transporter
N8A75_20820	COG1595	DNA-templated transcription, initiation
N8A75_20825	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N8A75_20830	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N8A75_20835	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N8A75_20840	COG4988	ABC transporter
N8A75_20845	COG1294	oxidase, subunit
N8A75_20850	COG1271	oxidase subunit
N8A75_20855	COG3493	citrate carrier protein
N8A75_20860	COG0501	Belongs to the peptidase M48B family
N8A75_20870	COG0726	polysaccharide deacetylase
N8A75_20875	COG3842	ATPase activity
N8A75_20880	COG2508	Transcriptional regulator
N8A75_20885	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_20890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N8A75_20900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N8A75_20910	COG4585	Histidine kinase
N8A75_20915	COG2197	response regulator
N8A75_20920	COG2195	Cleaves the N-terminal amino acid of tripeptides
N8A75_20935	COG4894	glucomannan catabolic process
N8A75_20940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N8A75_20945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N8A75_20950	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_20955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N8A75_20960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N8A75_20965	COG2610	gluconate transmembrane transporter activity
N8A75_20970	COG0500	methyltransferase
N8A75_20975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N8A75_20990	COG0693	protein deglycase activity
N8A75_20990	COG0753	catalase activity
N8A75_20995	COG2851	Citrate transporter
N8A75_21000	COG2273	Hydrolase Family 16
N8A75_21005	COG3711	transcriptional antiterminator
N8A75_21015	COG2270	Major facilitator Superfamily
N8A75_21020	COG0513	Belongs to the DEAD box helicase family
N8A75_21025	COG2755	lipolytic protein G-D-S-L family
N8A75_21025	COG3401	FG-GAP repeat protein
N8A75_21065	COG0697	spore germination
N8A75_21080	COG0589	response to stress
N8A75_21085	COG2723	6-phospho-beta-galactosidase activity
N8A75_21090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8A75_21090	COG2190	(PTS) system
N8A75_21090	COG1263	PTS System
N8A75_21105	COG5444	nuclease activity
N8A75_21120	COG3507	Belongs to the glycosyl hydrolase 43 family
N8A75_21145	COG2986	histidine ammonia-lyase
N8A75_21150	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N8A75_21155	COG1228	amidohydrolase
N8A75_21160	COG0010	Belongs to the arginase family
N8A75_21165	COG0833	amino acid
N8A75_21170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N8A75_21175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N8A75_21180	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N8A75_21185	COG2390	Transcriptional regulator
N8A75_21195	COG3192	ethanolamine utilization protein
N8A75_21200	COG2079	MmgE PrpD family protein
N8A75_21205	COG1473	amidohydrolase
N8A75_21210	COG1126	abc transporter atp-binding protein
N8A75_21215	COG0765	amino acid transport
N8A75_21220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8A75_21225	COG0456	acetyltransferase
N8A75_21230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8A75_21240	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
N8A75_21245	COG0561	phosphatase activity
N8A75_21275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N8A75_21280	COG5294	Protein conserved in bacteria
N8A75_21285	COG0577	efflux transmembrane transporter activity
N8A75_21290	COG1136	(ABC) transporter
N8A75_21295	COG2205	protein histidine kinase activity
N8A75_21300	COG0745	RESPONSE REGULATOR receiver
N8A75_21305	COG0191	fructose-bisphosphate aldolase activity
N8A75_21310	COG1082	Xylose isomerase domain protein TIM barrel
N8A75_21315	COG1082	Xylose isomerase domain protein TIM barrel
N8A75_21320	COG0673	inositol 2-dehydrogenase activity
N8A75_21325	COG2814	Major facilitator Superfamily
N8A75_21330	COG1082	Xylose isomerase domain protein TIM barrel
N8A75_21335	COG3962	Belongs to the TPP enzyme family
N8A75_21340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8A75_21350	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_21355	COG1349	DNA-binding transcription factor activity
N8A75_21360	COG0667	Aldo Keto reductase
N8A75_21375	COG2814	Major facilitator Superfamily
N8A75_21380	COG0326	Molecular chaperone. Has ATPase activity
N8A75_21390	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_21395	COG1309	transcriptional regulator
N8A75_21400	COG1012	belongs to the aldehyde dehydrogenase family
N8A75_21410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N8A75_21420	COG1714	RDD family
N8A75_21425	COG2311	Membrane
N8A75_21430	COG1917	Cupin 2, conserved barrel domain protein
N8A75_21435	COG1309	transcriptional regulator
N8A75_21440	COG1028	Short-chain dehydrogenase reductase Sdr
N8A75_21445	COG1846	Transcriptional regulator
N8A75_21450	COG1380	Effector of murein hydrolase LrgA
N8A75_21455	COG1346	cytolysis
N8A75_21460	COG5039	Polysaccharide pyruvyl transferase
N8A75_21465	COG1929	Belongs to the glycerate kinase type-1 family
N8A75_21470	COG1802	Transcriptional regulator
N8A75_21475	COG1070	Carbohydrate kinase
N8A75_21480	COG2610	gluconate transmembrane transporter activity
N8A75_21485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N8A75_21490	COG0450	alkyl hydroperoxide reductase
N8A75_21495	COG3634	alkyl hydroperoxide reductase activity
N8A75_21500	COG2723	6-phospho-beta-galactosidase activity
N8A75_21505	COG2190	(PTS) system
N8A75_21515	COG2188	Transcriptional regulator
N8A75_21525	COG1131	(ABC) transporter
N8A75_21530	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
N8A75_21550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N8A75_21565	COG1063	alcohol dehydrogenase
N8A75_21585	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
N8A75_21590	COG0456	acetyltransferase
N8A75_21595	COG0457	Tetratricopeptide repeat
N8A75_21605	COG0010	Belongs to the arginase family
N8A75_21610	COG0833	amino acid
N8A75_21615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N8A75_21635	COG5658	integral membrane protein
N8A75_21640	COG0640	Transcriptional regulator
N8A75_21645	COG3829	transcription factor binding
N8A75_21660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N8A75_21665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N8A75_21670	COG4853	Protein conserved in bacteria
N8A75_21675	COG4863	YycH protein
N8A75_21680	COG5002	protein histidine kinase activity
N8A75_21685	COG0745	RESPONSE REGULATOR receiver
N8A75_21715	COG0346	lactoylglutathione lyase activity
N8A75_21720	COG0305	Participates in initiation and elongation during chromosome replication
N8A75_21735	COG3093	addiction module antidote protein HigA
N8A75_21740	COG2807	transmembrane transport
N8A75_21745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N8A75_21750	COG0359	binds to the 23S rRNA
N8A75_21755	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
N8A75_21760	COG4241	membrane
N8A75_21770	COG5577	PFAM Coat F domain
N8A75_21775	COG1733	regulation of RNA biosynthetic process
N8A75_21780	COG1227	inorganic diphosphatase activity
N8A75_21790	COG2271	Major facilitator Superfamily
N8A75_21795	COG0789	Transcriptional regulator
N8A75_21795	COG4978	Transcriptional regulator
N8A75_21805	COG4319	ketosteroid isomerase
N8A75_21810	COG1357	PFAM Pentapeptide repeats (8 copies)
N8A75_21815	COG2814	Major facilitator Superfamily
N8A75_21820	COG0583	DNA-binding transcription factor activity
N8A75_21825	COG2153	protein acetylation
N8A75_21835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8A75_21840	COG1846	Transcriptional regulator
N8A75_21845	COG2153	protein acetylation
N8A75_21850	COG2364	Membrane
N8A75_21855	COG0456	acetyltransferase
N8A75_21860	COG2315	Protein conserved in bacteria
N8A75_21865	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N8A75_21870	COG1331	Highly conserved protein containing a thioredoxin domain
N8A75_21875	COG2814	Major facilitator Superfamily
N8A75_21880	COG1331	Highly conserved protein containing a thioredoxin domain
N8A75_21885	COG1266	CAAX protease self-immunity
N8A75_21890	COG0477	Major facilitator Superfamily
N8A75_21890	COG2814	Major facilitator Superfamily
N8A75_21895	COG0110	maltose O-acetyltransferase activity
N8A75_21900	COG0346	lactoylglutathione lyase activity
N8A75_21905	COG1609	Transcriptional regulator
N8A75_21910	COG0708	Exodeoxyribonuclease III
N8A75_21915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N8A75_21920	COG0629	single-stranded DNA binding
N8A75_21925	COG0360	Binds together with S18 to 16S ribosomal RNA
N8A75_21930	COG0012	GTP binding
N8A75_21935	COG0243	molybdopterin cofactor binding
N8A75_21940	COG4481	Protein conserved in bacteria
N8A75_21945	COG3949	Membrane
N8A75_21955	COG1475	DNA binding
N8A75_21960	COG1192	Involved in chromosome partitioning
N8A75_21970	COG1475	DNA binding
N8A75_21975	COG0357	Ribosomal RNA small subunit methyltransferase G
N8A75_21980	COG0445	tRNA wobble uridine modification
N8A75_21985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N8A75_21990	COG1847	R3H domain protein
N8A75_21995	COG0706	membrane insertase activity
N8A75_22000	COG0594	ribonuclease P activity