locus-tag	class	description
GII76_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII76_00010	COG0592	DNA-directed DNA polymerase activity
GII76_00015	COG2501	S4 domain
GII76_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII76_00030	COG0187	DNA topoisomerase II activity
GII76_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII76_00070	COG0517	IMP dehydrogenase activity
GII76_00070	COG0516	GMP reductase activity
GII76_00075	COG1686	Belongs to the peptidase S11 family
GII76_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII76_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII76_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII76_00100	COG1428	Deoxynucleoside kinase
GII76_00105	COG1428	Deoxynucleoside kinase
GII76_00110	COG3858	chitin binding
GII76_00110	COG1388	LysM domain
GII76_00115	COG1335	isochorismatase
GII76_00120	COG0590	tRNA wobble adenosine to inosine editing
GII76_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII76_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII76_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII76_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII76_00190	COG3853	Toxic anion resistance protein (TelA)
GII76_00195	COG1982	Orn Lys Arg decarboxylase major
GII76_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII76_00205	COG3870	Protein conserved in bacteria
GII76_00210	COG1728	Protein conserved in bacteria
GII76_00215	COG0470	DNA polymerase III
GII76_00220	COG1774	PSP1 C-terminal conserved region
GII76_00225	COG4467	Involved in initiation control of chromosome replication
GII76_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII76_00235	COG2827	Endonuclease containing a URI domain
GII76_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII76_00245	COG2002	toxin-antitoxin pair type II binding
GII76_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII76_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII76_00255	COG0084	hydrolase, TatD family'
GII76_00260	COG3584	3D domain protein
GII76_00260	COG3583	domain protein
GII76_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII76_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII76_00280	COG4466	Protein conserved in bacteria
GII76_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII76_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII76_00300	COG0251	oxidation-reduction process
GII76_00305	COG2088	sporulation resulting in formation of a cellular spore
GII76_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII76_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII76_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII76_00325	COG0193	aminoacyl-tRNA hydrolase activity
GII76_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII76_00340	COG2002	toxin-antitoxin pair type II binding
GII76_00345	COG2244	polysaccharide biosynthetic process
GII76_00350	COG3956	TIGRFAM MazG family protein
GII76_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII76_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII76_00375	COG1098	S1 RNA binding domain
GII76_00390	COG2208	phosphoserine phosphatase activity
GII76_00395	COG2304	oxidoreductase activity
GII76_00400	COG0515	serine threonine protein kinase
GII76_00405	COG0037	tRNA processing
GII76_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII76_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII76_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII76_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII76_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII76_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII76_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII76_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII76_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII76_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII76_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII76_00470	COG1396	sequence-specific DNA binding
GII76_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII76_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII76_00560	COG4463	regulation of RNA biosynthetic process
GII76_00565	COG3880	PFAM UvrB UvrC protein
GII76_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII76_00575	COG0542	response to heat
GII76_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII76_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII76_00590	COG4956	integral membrane protein (PIN domain superfamily)
GII76_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII76_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII76_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII76_00610	COG1045	serine acetyltransferase
GII76_00615	COG0215	cysteine-tRNA ligase activity
GII76_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII76_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII76_00630	COG3688	RNA-binding protein containing a PIN domain
GII76_00635	COG1595	DNA-templated transcription, initiation
GII76_00640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII76_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII76_00650	COG0250	Participates in transcription elongation, termination and antitermination
GII76_00655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GII76_00660	COG0081	regulation of translation
GII76_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII76_00670	COG0222	ribosome binding
GII76_00675	COG2813	Specifically methylates the guanine in position
GII76_00680	COG0085	RNA polymerase activity
GII76_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII76_00690	COG1358	cellular component organization or biogenesis
GII76_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII76_00700	COG0049	tRNA binding
GII76_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII76_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII76_00715	COG0596	Alpha beta hydrolase
GII76_00720	COG0051	transcription antitermination factor activity, RNA binding
GII76_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII76_00730	COG0088	Forms part of the polypeptide exit tunnel
GII76_00735	COG0089	rRNA binding
GII76_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII76_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GII76_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GII76_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GII76_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII76_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
GII76_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII76_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII76_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII76_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII76_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII76_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII76_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII76_00815	COG1841	ribosomal large subunit assembly
GII76_00820	COG0200	Binds to the 23S rRNA
GII76_00825	COG0201	protein transport
GII76_00830	COG0563	adenylate kinase activity
GII76_00835	COG0024	Methionine aminopeptidase
GII76_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII76_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GII76_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII76_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII76_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII76_00865	COG0202	RNA polymerase activity
GII76_00870	COG0203	ribosomal protein L17
GII76_00875	COG1122	ATPase activity
GII76_00880	COG1122	ATPase activity
GII76_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII76_00890	COG0101	tRNA pseudouridine synthase activity
GII76_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII76_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII76_00905	COG2226	methyltransferase
GII76_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII76_00920	COG0489	protein tyrosine kinase activity
GII76_00930	COG2194	sulfuric ester hydrolase activity
GII76_00935	COG0726	polysaccharide deacetylase
GII76_00970	COG2856	Zn peptidase
GII76_00980	COG1395	domain, Protein
GII76_01040	COG0305	Participates in initiation and elongation during chromosome replication
GII76_01050	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GII76_01130	COG1783	phage Terminase large subunit
GII76_01135	COG5518	Phage portal protein
GII76_01140	COG2369	cell adhesion
GII76_01150	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII76_01155	COG4653	Phage capsid family
GII76_01205	COG3953	SLT domain
GII76_01205	COG5280	Phage tail tape measure protein TP901
GII76_01210	COG1652	LysM domain
GII76_01215	COG4193	domain, Protein
GII76_01225	COG3628	GPW Gp25 family protein
GII76_01230	COG3299	homolog of phage Mu protein gp47
GII76_01235	COG3778	Protein conserved in bacteria
GII76_01275	COG1388	LysM domain
GII76_01275	COG3409	Peptidoglycan-binding domain 1 protein
GII76_01275	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII76_01285	COG5444	nuclease activity
GII76_01290	COG0457	Tetratricopeptide repeat
GII76_01305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII76_01360	COG0659	secondary active sulfate transmembrane transporter activity
GII76_01365	COG0385	Bile acid
GII76_01370	COG2819	hydrolase of the alpha beta superfamily
GII76_01375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII76_01380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII76_01385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII76_01390	COG2207	Transcriptional regulator
GII76_01390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII76_01395	COG3876	Protein conserved in bacteria
GII76_01400	COG1472	Belongs to the glycosyl hydrolase 3 family
GII76_01405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII76_01410	COG1263	PTS System
GII76_01410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_01415	COG1737	Transcriptional regulator
GII76_01420	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII76_01425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII76_01430	COG1683	Conserved Protein
GII76_01460	COG1595	DNA-templated transcription, initiation
GII76_01465	COG5662	AntiSigma factor
GII76_01470	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII76_01475	COG4856	YbbR-like protein
GII76_01480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII76_01490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII76_01500	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII76_01505	COG2169	Transcriptional regulator
GII76_01510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII76_01515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII76_01520	COG3002	Belongs to the UPF0753 family
GII76_01525	COG0288	reversible hydration of carbon dioxide
GII76_01535	COG5609	conserved protein (DUF2294)
GII76_01540	COG0640	Transcriptional regulator
GII76_01545	COG2814	Major facilitator Superfamily
GII76_01560	COG1404	Belongs to the peptidase S8 family
GII76_01580	COG1132	(ABC) transporter
GII76_01585	COG0596	Alpha beta hydrolase
GII76_01590	COG0745	RESPONSE REGULATOR receiver
GII76_01595	COG0642	Histidine kinase
GII76_01605	COG0515	serine threonine protein kinase
GII76_01620	COG1113	amino acid transport
GII76_01635	COG2602	Beta-lactamase
GII76_01640	COG2124	cytochrome p450
GII76_01650	COG0531	amino acid
GII76_01655	COG0584	glycerophosphoryl diester phosphodiesterase
GII76_01660	COG2271	Major facilitator Superfamily
GII76_01670	COG0456	acetyltransferase
GII76_01670	COG1846	Transcriptional regulator
GII76_01675	COG2271	Major facilitator Superfamily
GII76_01685	COG3409	Peptidoglycan-binding domain 1 protein
GII76_01690	COG0697	spore germination
GII76_01695	COG1917	Cupin 2, conserved barrel domain protein
GII76_01695	COG2207	Transcriptional regulator
GII76_01700	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII76_01705	COG3591	Belongs to the peptidase S1B family
GII76_01715	COG0596	Alpha beta hydrolase
GII76_01720	COG1183	phosphatidylcholine synthase activity
GII76_01725	COG0586	Pfam SNARE associated Golgi protein
GII76_01730	COG0688	phosphatidylethanolamine metabolic process
GII76_01745	COG1301	dicarboxylic acid transport
GII76_01750	COG1263	PTS System
GII76_01750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_01750	COG2190	(PTS) system
GII76_01755	COG0363	glucosamine-6-phosphate deaminase activity
GII76_01770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII76_01775	COG0833	amino acid
GII76_01780	COG2040	homocysteine
GII76_01790	COG1115	amino acid carrier protein
GII76_01795	COG2066	Belongs to the glutaminase family
GII76_01800	COG4191	Histidine kinase
GII76_01805	COG0784	Response regulator, receiver
GII76_01810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII76_01815	COG1012	belongs to the aldehyde dehydrogenase family
GII76_01820	COG2271	Major facilitator Superfamily
GII76_01825	COG4948	Mandelate Racemase Muconate Lactonizing
GII76_01830	COG2186	Transcriptional regulator
GII76_01835	COG2721	sulfolactate sulfo-lyase activity
GII76_01840	COG3173	Aminoglycoside phosphotransferase
GII76_01855	COG0745	RESPONSE REGULATOR receiver
GII76_01860	COG2205	protein histidine kinase activity
GII76_01865	COG1131	(ABC) transporter
GII76_01885	COG3773	Cell wall hydrolase
GII76_01890	COG2304	oxidoreductase activity
GII76_01900	COG3540	Alkaline phosphatase
GII76_01905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII76_01910	COG0805	protein transport
GII76_01915	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII76_01920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII76_01925	COG0477	Major facilitator Superfamily
GII76_01930	COG1309	transcriptional regulator
GII76_01935	COG0252	asparaginase activity
GII76_01940	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII76_01945	COG1714	RDD family
GII76_01950	COG1405	negative regulation of cell septum assembly
GII76_01950	COG3012	SEC-C Motif Domain Protein
GII76_01955	COG3290	protein histidine kinase activity
GII76_01960	COG3279	Response regulator of the LytR AlgR family
GII76_01965	COG4555	ABC transporter
GII76_01970	COG1668	transmembrane transport
GII76_01975	COG0667	Aldo Keto reductase
GII76_01990	COG1595	DNA-templated transcription, initiation
GII76_01995	COG1595	DNA-templated transcription, initiation
GII76_02000	COG1876	peptidase activity
GII76_02005	COG0457	Tetratricopeptide repeat
GII76_02010	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_02015	COG0366	Alpha amylase catalytic
GII76_02020	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII76_02025	COG1121	(ABC) transporter
GII76_02030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII76_02035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII76_02040	COG2310	stress, protein
GII76_02045	COG2310	stress, protein
GII76_02050	COG2310	stress, protein
GII76_02055	COG0861	Integral membrane protein TerC family
GII76_02065	COG3853	Toxic anion resistance protein (TelA)
GII76_02070	COG0477	Major facilitator Superfamily
GII76_02075	COG2814	Major facilitator Superfamily
GII76_02080	COG0640	Transcriptional regulator
GII76_02085	COG4175	Glycine betaine
GII76_02085	COG0517	IMP dehydrogenase activity
GII76_02090	COG4176	ABC-type proline glycine betaine transport system permease component
GII76_02095	COG2113	Glycine betaine
GII76_02100	COG1473	amidohydrolase
GII76_02105	COG1288	antiporter activity
GII76_02140	COG0039	L-malate dehydrogenase activity
GII76_02145	COG1620	l-lactate permease
GII76_02150	COG2814	Major facilitator Superfamily
GII76_02155	COG1846	Transcriptional regulator
GII76_02160	COG1280	lysine exporter protein (LysE YggA)
GII76_02165	COG3403	YqcI/YcgG family
GII76_02170	COG1113	amino acid transport
GII76_02175	COG3665	Urea carboxylase-associated protein
GII76_02180	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII76_02185	COG1660	Displays ATPase and GTPase activities
GII76_02190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII76_02195	COG2226	methyltransferase
GII76_02200	COG0583	DNA-binding transcription factor activity
GII76_02205	COG3458	cephalosporin-C deacetylase activity
GII76_02210	COG3541	Predicted nucleotidyltransferase
GII76_02215	COG0506	proline dehydrogenase activity
GII76_02220	COG1012	belongs to the aldehyde dehydrogenase family
GII76_02225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII76_02230	COG2508	Transcriptional regulator
GII76_02235	COG3689	TIGRFAM TIGR03943 family protein
GII76_02240	COG0701	Predicted permease
GII76_02245	COG2267	carboxylic ester hydrolase activity
GII76_02250	COG0492	ferredoxin-NADP+ reductase activity
GII76_02255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII76_02255	COG1587	Uroporphyrinogen-III synthase
GII76_02260	COG2146	nitrite reductase [NAD(P)H] activity
GII76_02265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII76_02270	COG0243	molybdopterin cofactor binding
GII76_02275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII76_02280	COG2223	nitrite transmembrane transporter activity
GII76_02285	COG1469	GTP cyclohydrolase I activity
GII76_02290	COG1376	ErfK ybiS ycfS ynhG family protein
GII76_02300	COG0523	cobalamin synthesis protein
GII76_02305	COG0765	amino acid transport
GII76_02310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII76_02320	COG1714	RDD family
GII76_02330	COG2723	6-phospho-beta-galactosidase activity
GII76_02340	COG3209	COG3209 Rhs family protein
GII76_02345	COG3290	protein histidine kinase activity
GII76_02345	COG0840	transmembrane signaling receptor activity
GII76_02350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII76_02355	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII76_02360	COG1733	regulation of RNA biosynthetic process
GII76_02365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII76_02370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII76_02375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII76_02380	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII76_02385	COG2814	Major facilitator Superfamily
GII76_02395	COG0697	spore germination
GII76_02400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII76_02410	COG2364	Membrane
GII76_02415	COG1126	abc transporter atp-binding protein
GII76_02420	COG0765	amino acid transport
GII76_02425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII76_02430	COG0583	DNA-binding transcription factor activity
GII76_02435	COG0163	prenyltransferase activity
GII76_02440	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII76_02455	COG0596	Alpha beta hydrolase
GII76_02460	COG3104	oligopeptide transport
GII76_02465	COG5434	Belongs to the glycosyl hydrolase 28 family
GII76_02475	COG0697	spore germination
GII76_02485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII76_02490	COG1136	(ABC) transporter
GII76_02495	COG0577	efflux transmembrane transporter activity
GII76_02500	COG0745	RESPONSE REGULATOR receiver
GII76_02505	COG3850	Histidine kinase
GII76_02505	COG5002	protein histidine kinase activity
GII76_02510	COG0457	Tetratricopeptide repeat
GII76_02530	COG0527	aspartate kinase activity
GII76_02535	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII76_02540	COG4605	iron ion homeostasis
GII76_02545	COG4604	ABC transporter, ATP-binding protein
GII76_02550	COG4607	ABC-type enterochelin transport system periplasmic component
GII76_02555	COG2814	Major facilitator Superfamily
GII76_02560	COG1309	transcriptional regulator
GII76_02565	COG0778	Nitroreductase
GII76_02570	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII76_02575	COG0640	Transcriptional regulator
GII76_02580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII76_02585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII76_02590	COG1012	belongs to the aldehyde dehydrogenase family
GII76_02595	COG4975	Glucose uptake
GII76_02600	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_02605	COG4549	nuclear export factor GLE1
GII76_02610	COG1276	copper resistance
GII76_02610	COG2372	response to copper ion
GII76_02615	COG1349	DNA-binding transcription factor activity
GII76_02625	COG2213	PTS system mannitol-specific
GII76_02630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII76_02635	COG0246	Mannitol dehydrogenase
GII76_02640	COG0473	3-isopropylmalate dehydrogenase activity
GII76_02645	COG0681	Belongs to the peptidase S26 family
GII76_02655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII76_02665	COG0561	phosphatase activity
GII76_02670	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII76_02675	COG1914	H( )-stimulated, divalent metal cation uptake system
GII76_02685	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII76_02690	COG1984	allophanate hydrolase subunit 2
GII76_02695	COG1414	Transcriptional regulator
GII76_02700	COG2755	lipolytic protein G-D-S-L family
GII76_02710	COG2329	Antibiotic biosynthesis monooxygenase
GII76_02715	COG0768	penicillin binding
GII76_02720	COG4989	oxidoreductase activity
GII76_02725	COG3711	transcriptional antiterminator
GII76_02730	COG0318	PFAM AMP-dependent synthetase and ligase
GII76_02735	COG2226	methyltransferase
GII76_02740	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_02745	COG1917	Cupin 2, conserved barrel domain protein
GII76_02750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII76_02755	COG3871	stress protein (general stress protein 26)
GII76_02765	COG2814	Major facilitator Superfamily
GII76_02770	COG1522	sequence-specific DNA binding
GII76_02775	COG0551	DNA topoisomerase type I activity
GII76_02775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII76_02780	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII76_02785	COG3706	GGDEF domain
GII76_02790	COG5298	Protein conserved in bacteria
GII76_02795	COG1215	transferase activity, transferring glycosyl groups
GII76_02805	COG0531	amino acid
GII76_02810	COG0494	nUDIX hydrolase
GII76_02815	COG0028	Belongs to the TPP enzyme family
GII76_02830	COG1914	H( )-stimulated, divalent metal cation uptake system
GII76_02835	COG2261	transglycosylase associated protein
GII76_02840	COG4876	unkown
GII76_02845	COG2217	Heavy metal translocating P-type atpase
GII76_02850	COG3729	General stress protein
GII76_02855	COG0662	Cupin 2, conserved barrel domain protein
GII76_02860	COG2329	Antibiotic biosynthesis monooxygenase
GII76_02865	COG3546	catalase activity
GII76_02870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII76_02875	COG3290	protein histidine kinase activity
GII76_02880	COG4565	transcriptional regulatory protein
GII76_02885	COG1301	dicarboxylic acid transport
GII76_02890	COG0628	permease
GII76_02895	COG1131	(ABC) transporter
GII76_02900	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII76_02910	COG1960	acyl-CoA dehydrogenase activity
GII76_02925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII76_02930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII76_02935	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII76_02940	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII76_02945	COG0513	Belongs to the DEAD box helicase family
GII76_02950	COG3402	PFAM membrane-flanked domain
GII76_02955	COG3428	Bacterial PH domain
GII76_02960	COG0705	Rhomboid family
GII76_02965	COG0736	holo-[acyl-carrier-protein] synthase activity
GII76_02970	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII76_02975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII76_02980	COG0864	Transcriptional regulator
GII76_02985	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII76_02990	COG1366	Belongs to the anti-sigma-factor antagonist family
GII76_02995	COG1366	Belongs to the anti-sigma-factor antagonist family
GII76_03000	COG2172	sigma factor antagonist activity
GII76_03005	COG2208	phosphoserine phosphatase activity
GII76_03010	COG1366	Belongs to the anti-sigma-factor antagonist family
GII76_03015	COG2172	sigma factor antagonist activity
GII76_03020	COG1191	sigma factor activity
GII76_03025	COG2208	phosphoserine phosphatase activity
GII76_03030	COG2183	response to ionizing radiation
GII76_03040	COG3091	SprT-like family
GII76_03080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII76_03120	COG1476	TRANSCRIPTIONal
GII76_03140	COG0693	protein deglycase activity
GII76_03145	COG1278	Cold shock
GII76_03150	COG1329	Transcriptional regulator
GII76_03155	COG0697	spore germination
GII76_03160	COG2207	Transcriptional regulator
GII76_03160	COG1917	Cupin 2, conserved barrel domain protein
GII76_03165	COG0697	spore germination
GII76_03170	COG2207	Transcriptional regulator
GII76_03170	COG3708	Transcriptional regulator
GII76_03175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII76_03180	COG0477	Major facilitator Superfamily
GII76_03190	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII76_03225	COG1309	transcriptional regulator
GII76_03230	COG0697	spore germination
GII76_03235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII76_03240	COG2030	dehydratase
GII76_03245	COG3545	Serine hydrolase
GII76_03250	COG1733	regulation of RNA biosynthetic process
GII76_03255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII76_03260	COG2814	Major facilitator Superfamily
GII76_03265	COG1309	transcriptional regulator
GII76_03275	COG0640	Transcriptional regulator
GII76_03280	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII76_03290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII76_03295	COG0697	spore germination
GII76_03300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII76_03305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII76_03310	COG0640	Transcriptional regulator
GII76_03315	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII76_03330	COG4585	Histidine kinase
GII76_03335	COG2197	response regulator
GII76_03340	COG2409	Drug exporters of the RND superfamily
GII76_03345	COG0596	Alpha beta hydrolase
GII76_03350	COG1811	Na channel or pump
GII76_03355	COG0789	Transcriptional regulator
GII76_03355	COG4978	Transcriptional regulator
GII76_03360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII76_03365	COG0778	Nitroreductase
GII76_03370	COG0346	lactoylglutathione lyase activity
GII76_03375	COG2259	Doxx family
GII76_03380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII76_03395	COG2323	membrane
GII76_03400	COG2323	membrane
GII76_03405	COG0071	Belongs to the small heat shock protein (HSP20) family
GII76_03420	COG1309	transcriptional regulator
GII76_03430	COG0456	acetyltransferase
GII76_03440	COG0673	inositol 2-dehydrogenase activity
GII76_03445	COG1609	Transcriptional regulator
GII76_03450	COG2814	Major facilitator Superfamily
GII76_03465	COG1113	amino acid transport
GII76_03470	COG2318	DinB family
GII76_03475	COG1846	Transcriptional regulator
GII76_03480	COG1033	growth of symbiont in host cell
GII76_03480	COG2409	Drug exporters of the RND superfamily
GII76_03485	COG0778	Nitroreductase
GII76_03490	COG1846	Transcriptional regulator
GII76_03495	COG2814	Major facilitator Superfamily
GII76_03500	COG0730	response to heat
GII76_03505	COG1802	Transcriptional regulator
GII76_03510	COG3858	chitin binding
GII76_03510	COG1388	LysM domain
GII76_03515	COG1819	glycosyl
GII76_03525	COG1785	Belongs to the alkaline phosphatase family
GII76_03530	COG5646	InterPro IPR014922
GII76_03540	COG0454	-acetyltransferase
GII76_03545	COG1078	dGTPase activity
GII76_03550	COG1388	LysM domain
GII76_03555	COG2814	Major facilitator Superfamily
GII76_03560	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII76_03565	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII76_03570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII76_03575	COG2723	6-phospho-beta-galactosidase activity
GII76_03580	COG2188	Transcriptional regulator
GII76_03585	COG1940	carbohydrate kinase activity
GII76_03590	COG1482	cell wall glycoprotein biosynthetic process
GII76_03595	COG4124	Belongs to the glycosyl hydrolase 26 family
GII76_03640	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII76_03645	COG0802	atpase or kinase
GII76_03650	COG1214	PFAM Peptidase M22, glycoprotease
GII76_03655	COG0456	acetyltransferase
GII76_03660	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII76_03665	COG0488	(ABC) transporter
GII76_03670	COG0315	cyclic pyranopterin monophosphate synthase activity
GII76_03675	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII76_03680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII76_03685	COG0805	protein transport
GII76_03695	COG1266	CAAX protease self-immunity
GII76_03700	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GII76_03705	COG0459	protein refolding
GII76_03715	COG1073	alpha beta
GII76_03720	COG0457	Tetratricopeptide repeat
GII76_03725	COG1063	alcohol dehydrogenase
GII76_03730	COG2211	Major facilitator Superfamily
GII76_03735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII76_03740	COG1842	Phage shock protein A
GII76_03745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII76_03750	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII76_03755	COG4260	virion core protein, lumpy skin disease virus
GII76_03765	COG2814	Major facilitator Superfamily
GII76_03770	COG1063	alcohol dehydrogenase
GII76_03775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII76_03780	COG0823	Involved in the tonB-independent uptake of proteins
GII76_03795	COG2267	carboxylic ester hydrolase activity
GII76_03805	COG2132	Multicopper oxidase
GII76_03810	COG1113	amino acid transport
GII76_03820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII76_03825	COG0714	Associated with various cellular activities
GII76_03830	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII76_03835	COG1305	Transglutaminase-like
GII76_03840	COG0519	Catalyzes the synthesis of GMP from XMP
GII76_03840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII76_03845	COG2252	PERMEase
GII76_03850	COG3064	Membrane
GII76_03860	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII76_03870	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII76_03875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII76_03880	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII76_03885	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII76_03890	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII76_03895	COG0047	phosphoribosylformylglycinamidine synthase activity
GII76_03900	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII76_03905	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII76_03910	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII76_03915	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII76_03920	COG0138	bifunctional purine biosynthesis protein purh
GII76_03925	COG0151	Belongs to the GarS family
GII76_03930	COG1522	sequence-specific DNA binding
GII76_03935	COG0531	amino acid
GII76_03945	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII76_03950	COG1470	cell adhesion involved in biofilm formation
GII76_03955	COG4496	protein, YerC YecD
GII76_03960	COG0069	glutamate synthase activity
GII76_03965	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII76_03970	COG0210	DNA helicase
GII76_03975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII76_03980	COG4851	CamS sex pheromone cAM373 precursor
GII76_03985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII76_03990	COG1285	pathogenesis
GII76_03995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII76_04000	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII76_04005	COG0154	amidase activity
GII76_04010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII76_04015	COG1309	transcriptional regulator
GII76_04020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII76_04025	COG1597	lipid kinase activity
GII76_04030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII76_04060	COG5444	nuclease activity
GII76_04070	COG3586	endonuclease activity
GII76_04080	COG0457	Tetratricopeptide repeat
GII76_04090	COG0217	transcriptional regulatory protein
GII76_04100	COG1309	transcriptional regulator
GII76_04105	COG3631	Ketosteroid isomerase-related protein
GII76_04110	COG0702	epimerase
GII76_04125	COG3546	catalase activity
GII76_04130	COG0454	-acetyltransferase
GII76_04140	COG5578	integral membrane protein
GII76_04145	COG2972	Histidine kinase
GII76_04150	COG4753	response regulator
GII76_04150	COG2207	Transcriptional regulator
GII76_04155	COG1653	transport
GII76_04160	COG1175	transmembrane transport
GII76_04165	COG0395	ABC-type sugar transport system, permease component
GII76_04170	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII76_04175	COG2207	Transcriptional regulator
GII76_04180	COG2755	lipolytic protein G-D-S-L family
GII76_04190	COG5578	integral membrane protein
GII76_04195	COG3401	FG-GAP repeat protein
GII76_04200	COG3401	FG-GAP repeat protein
GII76_04205	COG2755	lipolytic protein G-D-S-L family
GII76_04210	COG1874	Beta-galactosidase
GII76_04220	COG1653	transport
GII76_04225	COG4209	transmembrane transport
GII76_04230	COG0395	ABC-type sugar transport system, permease component
GII76_04235	COG1486	melibiose metabolic process
GII76_04240	COG2323	membrane
GII76_04245	COG2329	Antibiotic biosynthesis monooxygenase
GII76_04250	COG0346	lactoylglutathione lyase activity
GII76_04265	COG5583	Uncharacterized small protein (DUF2292)
GII76_04270	COG0670	Belongs to the BI1 family
GII76_04275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII76_04280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII76_04285	COG0134	indole-3-glycerol-phosphate synthase activity
GII76_04290	COG0133	tryptophan synthase activity
GII76_04295	COG0159	tryptophan synthase activity
GII76_04300	COG0135	phosphoribosylanthranilate isomerase activity
GII76_04325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII76_04335	COG0673	inositol 2-dehydrogenase activity
GII76_04355	COG0697	spore germination
GII76_04360	COG1846	Transcriptional regulator
GII76_04365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII76_04395	COG2124	cytochrome p450
GII76_04395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII76_04400	COG1368	sulfuric ester hydrolase activity
GII76_04405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII76_04410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII76_04415	COG1442	glycosyl transferase family 8
GII76_04420	COG1216	Glycosyl transferase, family 2
GII76_04425	COG1442	glycosyl transferase family 8
GII76_04430	COG2223	nitrite transmembrane transporter activity
GII76_04435	COG1011	Hydrolase
GII76_04440	COG0531	amino acid
GII76_04445	COG1012	belongs to the aldehyde dehydrogenase family
GII76_04450	COG0840	transmembrane signaling receptor activity
GII76_04455	COG0488	(ABC) transporter
GII76_04465	COG0789	Transcriptional regulator
GII76_04470	COG2814	Major facilitator Superfamily
GII76_04480	COG0488	(ABC) transporter
GII76_04485	COG0513	Belongs to the DEAD box helicase family
GII76_04490	COG0456	acetyltransferase
GII76_04495	COG2130	NADP-dependent
GII76_04500	COG2211	Major facilitator Superfamily
GII76_04505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GII76_04510	COG1120	ATPase activity
GII76_04515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII76_04520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII76_04525	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII76_04540	COG3866	Pectate lyase
GII76_04545	COG0471	metal ion transport
GII76_04550	COG3290	protein histidine kinase activity
GII76_04555	COG4565	transcriptional regulatory protein
GII76_04560	COG3181	Tripartite tricarboxylate transporter family receptor
GII76_04565	COG2851	Citrate transporter
GII76_04570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII76_04575	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII76_04580	COG1254	Belongs to the acylphosphatase family
GII76_04585	COG2258	MOSC domain
GII76_04605	COG0024	Methionine aminopeptidase
GII76_04610	COG1263	PTS System
GII76_04610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_04615	COG1368	sulfuric ester hydrolase activity
GII76_04630	COG1115	amino acid carrier protein
GII76_04635	COG0531	amino acid
GII76_04650	COG0697	spore germination
GII76_04655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_04655	COG1263	PTS System
GII76_04660	COG0366	Alpha amylase catalytic
GII76_04665	COG2188	Transcriptional regulator
GII76_04670	COG0778	Nitroreductase
GII76_04675	COG0737	Belongs to the 5'-nucleotidase family
GII76_04680	COG0693	protein deglycase activity
GII76_04685	COG2814	Major facilitator Superfamily
GII76_04690	COG4840	Belongs to the UPF0435 family
GII76_04695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII76_04700	COG4980	gas vesicle protein
GII76_04705	COG1295	ribonuclease BN
GII76_04710	COG0477	Major facilitator Superfamily
GII76_04715	COG0387	Pfam Sodium calcium exchanger
GII76_04725	COG0668	transmembrane transport
GII76_04730	COG0535	radical SAM domain protein
GII76_04740	COG0726	polysaccharide deacetylase
GII76_04745	COG2084	Dehydrogenase
GII76_04750	COG0598	Magnesium transport protein CorA
GII76_04755	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII76_04760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII76_04770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII76_04775	COG4637	Psort location Cytoplasmic, score
GII76_04780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII76_04785	COG0022	dehydrogenase e1 component
GII76_04790	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII76_04795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII76_04800	COG3284	Transcriptional regulator
GII76_04810	COG1742	UPF0060 membrane protein
GII76_04835	COG4842	Belongs to the WXG100 family
GII76_04840	COG1486	melibiose metabolic process
GII76_04845	COG1737	Transcriptional regulator
GII76_04850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_04850	COG1263	PTS System
GII76_04855	COG1132	(ABC) transporter
GII76_04860	COG1132	(ABC) transporter
GII76_04865	COG2259	Doxx family
GII76_04870	COG2514	catechol 2,3-dioxygenase activity
GII76_04875	COG4585	Histidine kinase
GII76_04880	COG2197	response regulator
GII76_04885	COG1131	(ABC) transporter
GII76_04890	COG0842	Transport permease protein
GII76_04890	COG1511	domain protein
GII76_04895	COG0842	Transport permease protein
GII76_04900	COG1695	Transcriptional regulator
GII76_04905	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII76_04910	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII76_04915	COG2318	DinB family
GII76_04920	COG2814	Major facilitator Superfamily
GII76_04925	COG1846	Transcriptional regulator
GII76_04930	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII76_04930	COG0392	lysyltransferase activity
GII76_04935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII76_04940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII76_04945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII76_04950	COG0384	phenazine biosynthesis protein PhzF
GII76_04955	COG0778	Nitroreductase
GII76_04970	COG1090	epimerase
GII76_04975	COG2137	regulation of response to DNA damage stimulus
GII76_04985	COG2814	Major facilitator Superfamily
GII76_05000	COG3103	Sh3 type 3 domain protein
GII76_05005	COG5658	integral membrane protein
GII76_05010	COG0596	Alpha beta hydrolase
GII76_05015	COG0463	Glycosyl transferase, family 2
GII76_05020	COG4485	Bacterial membrane protein, YfhO
GII76_05025	COG1988	membrane-bound metal-dependent
GII76_05030	COG1194	a g-specific adenine glycosylase
GII76_05040	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_05055	COG3557	Belongs to the UPF0374 family
GII76_05060	COG1132	(ABC) transporter
GII76_05065	COG4129	membrane
GII76_05070	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII76_05075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII76_05080	COG0735	belongs to the Fur family
GII76_05190	COG4326	sporulation control protein
GII76_05200	COG5577	PFAM Coat F domain
GII76_05205	COG3340	Belongs to the peptidase S51 family
GII76_05210	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII76_05215	COG0277	FAD linked oxidase domain protein
GII76_05225	COG0753	catalase activity
GII76_05230	COG1116	anion transmembrane transporter activity
GII76_05235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII76_05240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII76_05245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII76_05255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII76_05265	COG1476	TRANSCRIPTIONal
GII76_05275	COG3382	B3 4 domain protein
GII76_05280	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII76_05290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII76_05295	COG0789	Transcriptional regulator
GII76_05300	COG1664	Polymer-forming cytoskeletal
GII76_05305	COG1664	Polymer-forming cytoskeletal
GII76_05310	COG2766	serine protein kinase
GII76_05315	COG2718	Belongs to the UPF0229 family
GII76_05320	COG1846	Transcriptional regulator
GII76_05325	COG1566	PFAM secretion protein HlyD family protein
GII76_05330	COG2814	Major facilitator Superfamily
GII76_05335	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII76_05355	COG1725	Transcriptional regulator
GII76_05360	COG1131	(ABC) transporter
GII76_05365	COG1131	(ABC) transporter
GII76_05370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII76_05375	COG1278	Cold shock
GII76_05380	COG1464	Belongs to the NlpA lipoprotein family
GII76_05385	COG3706	GGDEF domain
GII76_05390	COG1823	symporter activity
GII76_05410	COG5577	PFAM Coat F domain
GII76_05415	COG4085	toxin activity
GII76_05415	COG1525	nuclease
GII76_05415	COG0737	Belongs to the 5'-nucleotidase family
GII76_05420	COG3764	Sortase (surface protein transpeptidase)
GII76_05425	COG0564	pseudouridine synthase activity
GII76_05435	COG0517	IMP dehydrogenase activity
GII76_05440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII76_05445	COG3153	acetyltransferase
GII76_05445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII76_05450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII76_05455	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII76_05460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII76_05465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII76_05470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII76_05475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII76_05480	COG4585	Histidine kinase
GII76_05480	COG2203	Gaf domain
GII76_05485	COG2197	response regulator
GII76_05490	COG0431	NADPH-dependent FMN reductase
GII76_05505	COG0791	NLP P60 protein
GII76_05505	COG1388	LysM domain
GII76_05510	COG1959	2 iron, 2 sulfur cluster binding
GII76_05515	COG0668	transmembrane transport
GII76_05520	COG2719	SpoVR family
GII76_05525	COG1785	Belongs to the alkaline phosphatase family
GII76_05530	COG0791	NLP P60 protein
GII76_05530	COG1388	LysM domain
GII76_05535	COG0583	DNA-binding transcription factor activity
GII76_05540	COG0372	Belongs to the citrate synthase family
GII76_05545	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_05550	COG0531	amino acid
GII76_05555	COG0733	neurotransmitter:sodium symporter activity
GII76_05560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII76_05565	COG0456	acetyltransferase
GII76_05580	COG1595	DNA-templated transcription, initiation
GII76_05585	COG0667	Aldo Keto reductase
GII76_05590	COG0204	Acyl-transferase
GII76_05595	COG1253	flavin adenine dinucleotide binding
GII76_05600	COG0789	Transcriptional regulator
GII76_05605	COG0436	Aminotransferase
GII76_05610	COG1253	flavin adenine dinucleotide binding
GII76_05615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII76_05620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII76_05625	COG0584	glycerophosphoryl diester phosphodiesterase
GII76_05635	COG0668	transmembrane transport
GII76_05640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII76_05645	COG0726	polysaccharide deacetylase
GII76_05650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII76_05655	COG1757	Na H antiporter
GII76_05660	COG0589	response to stress
GII76_05670	COG1132	(ABC) transporter
GII76_05675	COG1132	(ABC) transporter
GII76_05680	COG0702	epimerase
GII76_05700	COG0189	ligase activity
GII76_05705	COG0189	ligase activity
GII76_05710	COG4399	Belongs to the UPF0754 family
GII76_05715	COG3679	Belongs to the UPF0342 family
GII76_05720	COG4335	DNA alkylation repair
GII76_05725	COG0561	phosphatase activity
GII76_05730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII76_05735	COG0475	glutathione-regulated potassium exporter activity
GII76_05740	COG0490	domain, Protein
GII76_05750	COG1024	Enoyl-CoA hydratase
GII76_05760	COG4152	abc transporter atp-binding protein
GII76_05765	COG1668	transmembrane transport
GII76_05770	COG0420	3'-5' exonuclease activity
GII76_05775	COG4717	serine-type aminopeptidase activity
GII76_05780	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII76_05790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII76_05820	COG1846	Transcriptional regulator
GII76_05825	COG4980	gas vesicle protein
GII76_05840	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII76_05845	COG0537	adenosine 5'-monophosphoramidase activity
GII76_05850	COG1131	(ABC) transporter
GII76_05855	COG4473	ABC transporter
GII76_05865	COG1473	amidohydrolase
GII76_05870	COG3069	C4-dicarboxylate transmembrane transporter activity
GII76_05880	COG2329	Antibiotic biosynthesis monooxygenase
GII76_05885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII76_05890	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII76_05905	COG1309	transcriptional regulator
GII76_05910	COG1511	domain protein
GII76_05915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII76_05920	COG4377	Putative membrane peptidase family (DUF2324)
GII76_05930	COG1363	Peptidase, m42
GII76_05935	COG4405	Protein conserved in bacteria
GII76_05940	COG1301	dicarboxylic acid transport
GII76_05950	COG1234	tRNA 3'-trailer cleavage
GII76_05955	COG0095	Lipoate-protein ligase
GII76_05960	COG0702	epimerase
GII76_05965	COG0318	PFAM AMP-dependent synthetase and ligase
GII76_05975	COG0501	Belongs to the peptidase M48B family
GII76_05980	COG1404	Belongs to the peptidase S8 family
GII76_05985	COG0456	acetyltransferase
GII76_05990	COG0604	alcohol dehydrogenase
GII76_05995	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII76_06000	COG0406	alpha-ribazole phosphatase activity
GII76_06005	COG0183	Belongs to the thiolase family
GII76_06010	COG0318	PFAM AMP-dependent synthetase and ligase
GII76_06015	COG1268	BioY protein
GII76_06020	COG0840	transmembrane signaling receptor activity
GII76_06025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII76_06025	COG0723	plastoquinol--plastocyanin reductase activity
GII76_06030	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_06040	COG4903	ComK protein
GII76_06045	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_06055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII76_06070	COG0398	Pfam SNARE associated Golgi protein
GII76_06075	COG0681	Belongs to the peptidase S26 family
GII76_06080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII76_06085	COG1846	Transcriptional regulator
GII76_06090	COG0738	Major facilitator superfamily
GII76_06100	COG0561	phosphatase activity
GII76_06105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII76_06110	COG1609	Transcriptional regulator
GII76_06115	COG3180	Ammonia monooxygenase
GII76_06120	COG0477	Major facilitator Superfamily
GII76_06120	COG2814	Major facilitator Superfamily
GII76_06125	COG4533	DNA binding
GII76_06135	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII76_06140	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII76_06145	COG1074	ATP-dependent DNA helicase activity
GII76_06150	COG0420	3'-5' exonuclease activity
GII76_06155	COG0419	ATPase involved in DNA repair
GII76_06160	COG1403	HNH endonuclease
GII76_06200	COG5337	Spore coat protein CotH
GII76_06205	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII76_06215	COG1404	Belongs to the peptidase S8 family
GII76_06225	COG0367	asparagine synthase
GII76_06230	COG2318	DinB family
GII76_06235	COG1562	ergosterol biosynthetic process
GII76_06240	COG0534	Mate efflux family protein
GII76_06245	COG1917	Cupin 2, conserved barrel domain protein
GII76_06245	COG2207	Transcriptional regulator
GII76_06250	COG1609	Transcriptional regulator
GII76_06255	COG0673	inositol 2-dehydrogenase activity
GII76_06260	COG2318	DinB family
GII76_06265	COG1279	arginine transmembrane transporter activity
GII76_06270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII76_06275	COG1357	PFAM Pentapeptide repeats (8 copies)
GII76_06280	COG2267	carboxylic ester hydrolase activity
GII76_06285	COG0529	Catalyzes the synthesis of activated sulfate
GII76_06290	COG2046	Belongs to the sulfate adenylyltransferase family
GII76_06295	COG0175	sulfate reduction
GII76_06300	COG2045	Belongs to the ComB family
GII76_06305	COG1809	phosphosulfolactate synthase activity
GII76_06310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII76_06315	COG4948	Mandelate Racemase Muconate Lactonizing
GII76_06320	COG2814	Major facilitator Superfamily
GII76_06325	COG0454	-acetyltransferase
GII76_06330	COG2153	protein acetylation
GII76_06335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII76_06335	COG0646	methionine synthase
GII76_06340	COG1666	GTP binding
GII76_06345	COG2996	Protein conserved in bacteria
GII76_06365	COG1695	Transcriptional regulator
GII76_06380	COG3227	Zinc metalloprotease (Elastase)
GII76_06385	COG1307	EDD domain protein, DegV family
GII76_06390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII76_06405	COG0561	phosphatase activity
GII76_06410	COG1073	alpha beta
GII76_06415	COG2151	metal-sulfur cluster biosynthetic enzyme
GII76_06425	COG0277	FAD linked oxidase domain protein
GII76_06430	COG2271	Major facilitator Superfamily
GII76_06435	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII76_06450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII76_06455	COG0505	Belongs to the CarA family
GII76_06460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII76_06465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII76_06480	COG2267	carboxylic ester hydrolase activity
GII76_06490	COG1744	ABC transporter substrate-binding protein PnrA-like
GII76_06505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII76_06510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII76_06515	COG5504	Zn-dependent protease
GII76_06520	COG0444	Belongs to the ABC transporter superfamily
GII76_06525	COG4608	Belongs to the ABC transporter superfamily
GII76_06535	COG0601	transmembrane transport
GII76_06540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII76_06550	COG0180	Tryptophanyl-tRNA synthetase
GII76_06555	COG4166	transmembrane transport
GII76_06560	COG0601	transmembrane transport
GII76_06565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII76_06570	COG0444	Belongs to the ABC transporter superfamily
GII76_06575	COG4608	Belongs to the ABC transporter superfamily
GII76_06580	COG2814	Major facilitator Superfamily
GII76_06585	COG0456	acetyltransferase
GII76_06590	COG1393	Belongs to the ArsC family
GII76_06595	COG0861	Integral membrane protein TerC family
GII76_06605	COG4862	establishment of competence for transformation
GII76_06615	COG4469	Competence protein
GII76_06620	COG1164	Oligoendopeptidase f
GII76_06635	COG2346	COG2346, Truncated hemoglobins
GII76_06640	COG0741	lytic transglycosylase activity
GII76_06645	COG4116	CYTH
GII76_06655	COG2357	RelA SpoT domain protein
GII76_06660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII76_06665	COG0564	pseudouridine synthase activity
GII76_06670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII76_06675	COG0475	glutathione-regulated potassium exporter activity
GII76_06675	COG0569	domain protein
GII76_06680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII76_06685	COG0352	thiamine-phosphate diphosphorylase activity
GII76_06690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII76_06695	COG2104	thiamine diphosphate biosynthetic process
GII76_06700	COG2022	thiamine diphosphate biosynthetic process
GII76_06705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII76_06710	COG0351	phosphomethylpyrimidine kinase
GII76_06715	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII76_06770	COG0210	DNA helicase
GII76_06780	COG2153	protein acetylation
GII76_06785	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII76_06790	COG2382	esterase
GII76_06795	COG0626	cystathionine gamma-synthase activity
GII76_06800	COG0626	cystathionine gamma-synthase activity
GII76_06805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII76_06810	COG5505	Protein of unknown function (DUF819)
GII76_06820	COG0582	viral genome integration into host DNA
GII76_06905	COG0582	viral genome integration into host DNA
GII76_06940	COG0739	heme binding
GII76_06940	COG0741	lytic transglycosylase activity
GII76_06940	COG1196	nuclear chromosome segregation
GII76_06960	COG0457	Tetratricopeptide repeat
GII76_06965	COG5444	nuclease activity
GII76_07025	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII76_07030	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_07040	COG3711	transcriptional antiterminator
GII76_07040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII76_07045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII76_07045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII76_07045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII76_07050	COG1482	cell wall glycoprotein biosynthetic process
GII76_07060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII76_07070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII76_07085	COG0109	protoheme IX farnesyltransferase activity
GII76_07095	COG0726	polysaccharide deacetylase
GII76_07110	COG5504	Zn-dependent protease
GII76_07115	COG2205	protein histidine kinase activity
GII76_07125	COG3383	formate dehydrogenase (NAD+) activity
GII76_07130	COG2427	Protein of unknown function (DUF1641)
GII76_07140	COG1051	belongs to the nudix hydrolase family
GII76_07150	COG2124	cytochrome p450
GII76_07155	COG1819	glycosyl
GII76_07165	COG1587	Uroporphyrinogen-III synthase
GII76_07170	COG0390	transport system, permease component
GII76_07175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII76_07180	COG0697	spore germination
GII76_07185	COG4297	protein containing double-stranded beta helix domain
GII76_07195	COG1252	NADH dehydrogenase
GII76_07200	COG1904	glucuronate isomerase
GII76_07205	COG2211	Major facilitator Superfamily
GII76_07210	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII76_07215	COG1063	alcohol dehydrogenase
GII76_07220	COG1312	Catalyzes the dehydration of D-mannonate
GII76_07225	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_07230	COG2271	Major facilitator Superfamily
GII76_07235	COG1609	Transcriptional regulator
GII76_07240	COG0246	Mannitol dehydrogenase
GII76_07245	COG2721	sulfolactate sulfo-lyase activity
GII76_07250	COG0730	response to heat
GII76_07255	COG2318	DinB family
GII76_07260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII76_07265	COG0457	Tetratricopeptide repeat
GII76_07275	COG2350	Protein conserved in bacteria
GII76_07280	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII76_07280	COG3409	Peptidoglycan-binding domain 1 protein
GII76_07280	COG1388	LysM domain
GII76_07290	COG4195	phage-related replication protein
GII76_07295	COG3546	catalase activity
GII76_07300	COG2856	Zn peptidase
GII76_07305	COG1396	sequence-specific DNA binding
GII76_07315	COG1522	sequence-specific DNA binding
GII76_07320	COG1484	DNA-dependent DNA replication
GII76_07340	COG1595	DNA-templated transcription, initiation
GII76_07345	COG3728	DNA packaging
GII76_07345	COG5484	DNA packaging
GII76_07350	COG1783	phage Terminase large subunit
GII76_07355	COG5518	Phage portal protein
GII76_07360	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII76_07365	COG4653	Phage capsid family
GII76_07415	COG3953	SLT domain
GII76_07415	COG5412	phage tail tape measure protein
GII76_07415	COG3953	SLT domain
GII76_07415	COG5412	phage tail tape measure protein
GII76_07420	COG1652	LysM domain
GII76_07425	COG4193	domain, Protein
GII76_07435	COG3628	GPW Gp25 family protein
GII76_07440	COG3299	homolog of phage Mu protein gp47
GII76_07445	COG3778	Protein conserved in bacteria
GII76_07485	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII76_07485	COG3409	Peptidoglycan-binding domain 1 protein
GII76_07505	COG0306	phosphate transporter
GII76_07510	COG1392	Phosphate transport regulator
GII76_07515	COG0531	amino acid
GII76_07520	COG0346	lactoylglutathione lyase activity
GII76_07525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII76_07530	COG0463	Glycosyl transferase, family 2
GII76_07535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII76_07540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII76_07545	COG2362	D-Aminopeptidase
GII76_07550	COG0601	transmembrane transport
GII76_07555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII76_07560	COG0444	Belongs to the ABC transporter superfamily
GII76_07565	COG4166	transmembrane transport
GII76_07570	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII76_07575	COG4948	Mandelate Racemase Muconate Lactonizing
GII76_07580	COG0791	NLP P60 protein
GII76_07585	COG4608	Belongs to the ABC transporter superfamily
GII76_07590	COG2706	6-phosphogluconolactonase activity
GII76_07595	COG1834	amidinotransferase
GII76_07600	COG1607	acyl-coa hydrolase
GII76_07605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII76_07605	COG1017	nitric oxide dioxygenase activity
GII76_07615	COG2323	membrane
GII76_07620	COG2318	DinB family
GII76_07625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII76_07630	COG2076	Multidrug Resistance protein
GII76_07635	COG2076	Multidrug Resistance protein
GII76_07640	COG0788	formyltetrahydrofolate deformylase activity
GII76_07645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII76_07650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII76_07655	COG1764	response to oxidative stress
GII76_07660	COG1846	Transcriptional regulator
GII76_07665	COG1764	response to oxidative stress
GII76_07670	COG0590	tRNA wobble adenosine to inosine editing
GII76_07675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII76_07680	COG1404	Belongs to the peptidase S8 family
GII76_07685	COG1366	Belongs to the anti-sigma-factor antagonist family
GII76_07690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII76_07695	COG1122	ATPase activity
GII76_07700	COG4721	ABC-type cobalt transport system, permease component
GII76_07710	COG0745	RESPONSE REGULATOR receiver
GII76_07715	COG3850	Histidine kinase
GII76_07715	COG5002	protein histidine kinase activity
GII76_07720	COG3212	peptidase
GII76_07725	COG3212	peptidase
GII76_07735	COG2239	Acts as a magnesium transporter
GII76_07740	COG0789	Transcriptional regulator
GII76_07755	COG1846	Transcriptional regulator
GII76_07760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII76_07765	COG0726	polysaccharide deacetylase
GII76_07770	COG1408	metallophosphoesterase
GII76_07780	COG0463	Glycosyl transferase, family 2
GII76_07785	COG1793	dna ligase
GII76_07785	COG3285	dna ligase
GII76_07790	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII76_07795	COG5001	Diguanylate cyclase
GII76_07795	COG3300	MHYT domain
GII76_07800	COG0586	Pfam SNARE associated Golgi protein
GII76_07805	COG0861	Integral membrane protein TerC family
GII76_07810	COG1191	sigma factor activity
GII76_07830	COG0501	Belongs to the peptidase M48B family
GII76_07835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII76_07850	COG3594	Acyltransferase
GII76_07855	COG5002	protein histidine kinase activity
GII76_07860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII76_07870	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII76_07875	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII76_07880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII76_07885	COG0436	Aminotransferase
GII76_07890	COG1850	ribulose-bisphosphate carboxylase activity
GII76_07895	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII76_07900	COG0235	Class ii aldolase
GII76_07905	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII76_07910	COG3339	Conserved Protein
GII76_07925	COG3852	Histidine kinase
GII76_07930	COG1846	Transcriptional regulator
GII76_07935	COG1360	Flagellar Motor Protein
GII76_07940	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII76_07945	COG0542	response to heat
GII76_07950	COG3949	Membrane
GII76_07955	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII76_07960	COG0720	synthase
GII76_07965	COG0602	queuosine metabolic process
GII76_07970	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII76_07975	COG1733	regulation of RNA biosynthetic process
GII76_07980	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_07985	COG4641	Protein conserved in bacteria
GII76_07985	COG1388	LysM domain
GII76_07990	COG1388	LysM domain
GII76_07995	COG3858	chitin binding
GII76_08005	COG4873	Protein conserved in bacteria
GII76_08015	COG3773	Cell wall hydrolase
GII76_08020	COG2244	polysaccharide biosynthetic process
GII76_08025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII76_08030	COG2217	Heavy metal translocating P-type atpase
GII76_08040	COG0006	proline dipeptidase activity
GII76_08045	COG1609	Transcriptional regulator
GII76_08050	COG3711	transcriptional antiterminator
GII76_08055	COG1263	PTS System
GII76_08055	COG2190	(PTS) system
GII76_08055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_08060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII76_08065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII76_08075	COG1533	DNA photolyase activity
GII76_08080	COG0456	acetyltransferase
GII76_08085	COG0840	transmembrane signaling receptor activity
GII76_08090	COG2084	Dehydrogenase
GII76_08095	COG2340	Cysteine-rich secretory protein family
GII76_08100	COG0768	penicillin binding
GII76_08105	COG4191	Histidine kinase
GII76_08110	COG0436	Aminotransferase
GII76_08120	COG0835	chemotaxis
GII76_08120	COG0784	Response regulator, receiver
GII76_08130	COG2814	Major facilitator Superfamily
GII76_08135	COG1376	ErfK ybiS ycfS ynhG family protein
GII76_08140	COG1408	metallophosphoesterase
GII76_08145	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_08150	COG2200	EAL domain
GII76_08155	COG4703	Protein of unknown function (DUF1797)
GII76_08160	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII76_08170	COG0517	IMP dehydrogenase activity
GII76_08180	COG0716	FMN binding
GII76_08190	COG0716	FMN binding
GII76_08195	COG2171	N-acyltransferase activity
GII76_08200	COG1473	amidohydrolase
GII76_08210	COG0668	transmembrane transport
GII76_08215	COG0450	alkyl hydroperoxide reductase
GII76_08220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII76_08235	COG0746	molybdenum cofactor guanylyltransferase activity
GII76_08240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII76_08245	COG0303	'Molybdopterin
GII76_08250	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII76_08255	COG0314	molybdopterin synthase activity
GII76_08260	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII76_08265	COG1132	(ABC) transporter
GII76_08270	COG1132	(ABC) transporter
GII76_08280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII76_08285	COG1136	(ABC) transporter
GII76_08290	COG0577	efflux transmembrane transporter activity
GII76_08295	COG1349	DNA-binding transcription factor activity
GII76_08300	COG1105	Belongs to the carbohydrate kinase PfkB family
GII76_08305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII76_08305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII76_08305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII76_08310	COG0681	Belongs to the peptidase S26 family
GII76_08320	COG0488	(ABC) transporter
GII76_08325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII76_08330	COG2309	aminopeptidase activity
GII76_08340	COG1077	Cell shape determining protein MreB Mrl
GII76_08345	COG2002	toxin-antitoxin pair type II binding
GII76_08350	COG3852	Histidine kinase
GII76_08355	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII76_08355	COG2105	PFAM AIG2 family protein
GII76_08360	COG0569	domain protein
GII76_08365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII76_08370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII76_08380	COG0561	phosphatase activity
GII76_08385	COG0242	peptide deformylase activity
GII76_08395	COG0497	DNA recombination
GII76_08400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII76_08405	COG0022	dehydrogenase e1 component
GII76_08410	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII76_08415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII76_08420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII76_08430	COG1982	Orn Lys Arg decarboxylase major
GII76_08435	COG4476	Belongs to the UPF0223 family
GII76_08440	COG4493	Belongs to the UPF0637 family
GII76_08450	COG0483	inositol monophosphate 1-phosphatase activity
GII76_08460	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII76_08480	COG1595	DNA-templated transcription, initiation
GII76_08510	COG4896	Protein conserved in bacteria
GII76_08520	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII76_08525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII76_08530	COG2066	Belongs to the glutaminase family
GII76_08535	COG4838	Belongs to the UPF0358 family
GII76_08540	COG0772	Belongs to the SEDS family
GII76_08545	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII76_08550	COG1612	heme a metabolic process
GII76_08555	COG0109	protoheme IX farnesyltransferase activity
GII76_08560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII76_08560	COG2010	Cytochrome c
GII76_08565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII76_08570	COG1845	cytochrome c oxidase, subunit III
GII76_08575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII76_08580	COG3336	cytochrome c oxidase
GII76_08590	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII76_08595	COG2340	Cysteine-rich secretory protein family
GII76_08610	COG3679	Belongs to the UPF0342 family
GII76_08615	COG4471	UPF0298 protein
GII76_08620	COG0742	ribosomal rna small subunit methyltransferase
GII76_08625	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII76_08630	COG3314	Sporulation integral membrane protein YlbJ
GII76_08635	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII76_08640	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII76_08645	COG1323	Belongs to the UPF0348 family
GII76_08655	COG1399	metal-binding, possibly nucleic acid-binding protein
GII76_08660	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GII76_08670	COG0454	-acetyltransferase
GII76_08675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII76_08680	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII76_08685	COG2001	Belongs to the MraZ family
GII76_08690	COG0275	rRNA processing
GII76_08695	COG4839	cell division protein FtsL
GII76_08705	COG0768	penicillin binding
GII76_08710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII76_08715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII76_08720	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII76_08725	COG0772	Belongs to the SEDS family
GII76_08730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII76_08735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII76_08740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII76_08745	COG3879	Bacterial protein of unknown function (DUF881)
GII76_08750	COG3879	Bacterial protein of unknown function (DUF881)
GII76_08755	COG3856	small basic protein
GII76_08760	COG0849	cell division
GII76_08765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII76_08770	COG4412	M6 family metalloprotease domain protein
GII76_08770	COG1404	Belongs to the peptidase S8 family
GII76_08780	COG1191	sigma factor activity
GII76_08785	COG1191	sigma factor activity
GII76_08790	COG1119	ATPase activity
GII76_08795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII76_08800	COG1873	PFAM PRC-barrel domain
GII76_08810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII76_08815	COG1799	cell septum assembly
GII76_08820	COG0762	integral membrane protein
GII76_08825	COG2302	S4 RNA-binding domain
GII76_08830	COG3599	regulation of cell shape
GII76_08835	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII76_08840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII76_08845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII76_08850	COG0564	pseudouridine synthase activity
GII76_08855	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII76_08860	COG2233	PERMEase
GII76_08865	COG0540	Belongs to the ATCase OTCase family
GII76_08870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII76_08875	COG0505	Belongs to the CarA family
GII76_08880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII76_08885	COG0543	2 iron, 2 sulfur cluster binding
GII76_08890	COG0167	dihydroorotate dehydrogenase activity
GII76_08895	COG0284	orotidine-5'-phosphate decarboxylase activity
GII76_08900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII76_08905	COG0175	sulfate reduction
GII76_08910	COG0306	phosphate transporter
GII76_08915	COG2046	Belongs to the sulfate adenylyltransferase family
GII76_08920	COG0529	Catalyzes the synthesis of activated sulfate
GII76_08925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII76_08930	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII76_08935	COG1648	precorrin-2 dehydrogenase activity
GII76_08945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII76_08950	COG1561	YicC-like family, N-terminal region
GII76_08955	COG2052	Domain of unknown function (DUF370)
GII76_08960	COG0194	GDP metabolic process
GII76_08965	COG1758	RNA polymerase activity
GII76_08970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII76_08975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII76_08980	COG0242	peptide deformylase activity
GII76_08985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII76_08990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII76_08990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII76_08995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII76_09000	COG0631	protein serine/threonine phosphatase activity
GII76_09005	COG0515	serine threonine protein kinase
GII76_09005	COG2815	serine threonine protein kinase
GII76_09010	COG1162	GTPase activity
GII76_09015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII76_09020	COG1564	THIamine pyrophosphokinase
GII76_09030	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII76_09035	COG1302	Protein conserved in bacteria
GII76_09040	COG1461	Dihydroxyacetone kinase
GII76_09045	COG1760	l-serine dehydratase
GII76_09050	COG1760	l-serine dehydratase
GII76_09055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII76_09060	COG2050	protein possibly involved in aromatic compounds catabolism
GII76_09060	COG1349	DNA-binding transcription factor activity
GII76_09065	COG0416	fatty acid biosynthetic process
GII76_09070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII76_09075	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_09080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII76_09085	COG0571	ribonuclease III activity
GII76_09090	COG1196	nuclear chromosome segregation
GII76_09095	COG0552	protein localization to endoplasmic reticulum
GII76_09105	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII76_09110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII76_09115	COG0228	four-way junction DNA binding
GII76_09120	COG1837	Belongs to the UPF0109 family
GII76_09130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII76_09135	COG0336	Belongs to the RNA methyltransferase TrmD family
GII76_09140	COG0335	large ribosomal subunit rRNA binding
GII76_09145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII76_09150	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII76_09160	COG2257	FlhB HrpN YscU SpaS Family
GII76_09165	COG0045	succinate-CoA ligase (ADP-forming) activity
GII76_09170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII76_09175	COG0758	DNA mediated transformation
GII76_09180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII76_09185	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII76_09190	COG4974	Belongs to the 'phage' integrase family
GII76_09195	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII76_09200	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII76_09205	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII76_09210	COG1815	bacterial-type flagellum-dependent cell motility
GII76_09215	COG1558	bacterial-type flagellum-dependent cell motility
GII76_09220	COG1677	Flagellar hook-basal body complex protein FliE
GII76_09225	COG1766	The M ring may be actively involved in energy transduction
GII76_09230	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII76_09235	COG1317	bacterial-type flagellum organization
GII76_09240	COG1157	protein secretion by the type III secretion system
GII76_09245	COG2882	bacterial-type flagellum organization
GII76_09250	COG3334	PFAM MgtE intracellular
GII76_09255	COG3144	bacterial-type flagellum assembly
GII76_09260	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII76_09265	COG4786	Flagellar basal body rod
GII76_09270	COG1582	Flagellar protein (FlbD)
GII76_09275	COG1580	Controls the rotational direction of flagella during chemotaxis
GII76_09280	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII76_09285	COG1776	CheC inhibitor of MCP methylation
GII76_09285	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII76_09290	COG2201	protein-glutamate methylesterase activity
GII76_09295	COG3190	flagellar
GII76_09300	COG1338	Plays a role in the flagellum-specific transport system
GII76_09305	COG1987	bacterial-type flagellum assembly
GII76_09310	COG1684	flagellar biosynthetic protein fliR
GII76_09315	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII76_09320	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII76_09325	COG1419	protein localization to endoplasmic reticulum
GII76_09330	COG0455	bacterial-type flagellum organization
GII76_09335	COG2201	protein-glutamate methylesterase activity
GII76_09340	COG0643	Histidine kinase
GII76_09340	COG2198	Histidine kinase
GII76_09345	COG0835	chemotaxis
GII76_09350	COG1776	CheC inhibitor of MCP methylation
GII76_09355	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII76_09360	COG1191	sigma factor activity
GII76_09370	COG0052	Belongs to the universal ribosomal protein uS2 family
GII76_09375	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII76_09380	COG0528	UMP kinase activity
GII76_09385	COG0233	cytoplasmic translational termination
GII76_09390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII76_09395	COG4589	Belongs to the CDS family
GII76_09400	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII76_09405	COG0750	zinc metalloprotease
GII76_09410	COG0442	prolyl-tRNA aminoacylation
GII76_09415	COG2176	DNA-directed DNA polymerase activity
GII76_09420	COG0779	Required for maturation of 30S ribosomal subunits
GII76_09425	COG0195	Participates in both transcription termination and antitermination
GII76_09430	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII76_09435	COG1358	cellular component organization or biogenesis
GII76_09440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII76_09445	COG1550	Protein conserved in bacteria
GII76_09450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII76_09455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII76_09460	COG0196	riboflavin kinase activity
GII76_09465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII76_09470	COG1185	polyribonucleotide nucleotidyltransferase activity
GII76_09475	COG0726	polysaccharide deacetylase
GII76_09480	COG0612	Peptidase, M16
GII76_09485	COG1873	PFAM PRC-barrel domain
GII76_09490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII76_09495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII76_09500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII76_09505	COG0527	aspartate kinase activity
GII76_09510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII76_09515	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII76_09520	COG0740	serine-type endopeptidase activity
GII76_09530	COG1674	ftsk spoiiie
GII76_09530	COG4980	gas vesicle protein
GII76_09535	COG2188	Transcriptional regulator
GII76_09540	COG2814	Major facilitator Superfamily
GII76_09545	COG0612	Peptidase, M16
GII76_09550	COG0612	Peptidase, M16
GII76_09555	COG0300	oxidoreductase activity
GII76_09570	COG1426	Protein conserved in bacteria
GII76_09575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII76_09580	COG1546	Belongs to the CinA family
GII76_09580	COG1058	Belongs to the CinA family
GII76_09585	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII76_09590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII76_09595	COG1418	mRNA catabolic process
GII76_09600	COG1692	metallophosphoesterase
GII76_09605	COG2359	stage V sporulation protein S
GII76_09610	COG1063	alcohol dehydrogenase
GII76_09615	COG0156	8-amino-7-oxononanoate synthase activity
GII76_09620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII76_09625	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII76_09635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII76_09640	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII76_09655	COG3226	Transcriptional regulator
GII76_09660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII76_09670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII76_09675	COG3321	synthase
GII76_09680	COG2070	2-Nitropropane dioxygenase
GII76_09680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII76_09685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII76_09690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII76_09695	COG3425	synthase
GII76_09700	COG1024	Enoyl-CoA hydratase
GII76_09705	COG1024	Enoyl-CoA hydratase
GII76_09710	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_09710	COG0300	oxidoreductase activity
GII76_09710	COG0318	PFAM AMP-dependent synthetase and ligase
GII76_09710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII76_09710	COG3321	synthase
GII76_09715	COG4221	oxidoreductase activity
GII76_09715	COG3321	synthase
GII76_09715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII76_09715	COG0300	oxidoreductase activity
GII76_09720	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_09720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII76_09720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII76_09720	COG3321	synthase
GII76_09720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII76_09725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII76_09725	COG4221	oxidoreductase activity
GII76_09725	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_09725	COG3321	synthase
GII76_09730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII76_09730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GII76_09730	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII76_09730	COG3321	synthase
GII76_09735	COG2124	cytochrome p450
GII76_09745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII76_09750	COG1404	Belongs to the peptidase S8 family
GII76_09760	COG4195	phage-related replication protein
GII76_09765	COG1764	response to oxidative stress
GII76_09770	COG2076	Multidrug Resistance protein
GII76_09775	COG2076	Multidrug Resistance protein
GII76_09790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII76_09795	COG1923	regulation of RNA biosynthetic process
GII76_09810	COG1780	Probably involved in ribonucleotide reductase function
GII76_09815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII76_09820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII76_09825	COG4112	unkown
GII76_09830	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII76_09835	COG0464	growth
GII76_09840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII76_09845	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII76_09850	COG0789	Transcriptional regulator
GII76_09855	COG0174	glutamine synthetase
GII76_09895	COG1598	PFAM Uncharacterised protein family UPF0150
GII76_09975	COG0463	Glycosyl transferase, family 2
GII76_09990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII76_10005	COG3655	Transcriptional regulator
GII76_10020	COG0135	phosphoribosylanthranilate isomerase activity
GII76_10035	COG3507	Belongs to the glycosyl hydrolase 43 family
GII76_10040	COG1940	carbohydrate kinase activity
GII76_10045	COG2115	Belongs to the xylose isomerase family
GII76_10050	COG1070	Carbohydrate kinase
GII76_10060	COG1525	nuclease
GII76_10065	COG2814	Major facilitator Superfamily
GII76_10070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII76_10080	COG0756	dUTP diphosphatase activity
GII76_10115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII76_10125	COG3832	glyoxalase III activity
GII76_10170	COG4195	phage-related replication protein
GII76_10180	COG0346	lactoylglutathione lyase activity
GII76_10185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII76_10190	COG1388	LysM domain
GII76_10195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII76_10200	COG4224	UPF0291 protein
GII76_10205	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII76_10215	COG3763	UPF0154 protein
GII76_10225	COG0785	Cytochrome C biogenesis protein
GII76_10230	COG2201	protein-glutamate methylesterase activity
GII76_10235	COG4846	Membrane protein involved in cytochrome C biogenesis
GII76_10245	COG0071	Belongs to the small heat shock protein (HSP20) family
GII76_10260	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII76_10265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII76_10285	COG0824	Thioesterase
GII76_10295	COG4841	protein insertion into membrane
GII76_10300	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII76_10305	COG1832	CoA-binding protein
GII76_10310	COG0187	DNA topoisomerase II activity
GII76_10315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII76_10325	COG1115	amino acid carrier protein
GII76_10340	COG5520	Belongs to the glycosyl hydrolase 30 family
GII76_10345	COG3507	Belongs to the glycosyl hydrolase 43 family
GII76_10350	COG2246	polysaccharide biosynthetic process
GII76_10355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII76_10360	COG0586	Pfam SNARE associated Golgi protein
GII76_10365	COG2404	hydrolase activity, acting on ester bonds
GII76_10370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII76_10375	COG1024	Enoyl-CoA hydratase
GII76_10380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII76_10385	COG0511	ligase activity, forming carbon-carbon bonds
GII76_10390	COG0439	Biotin carboxylase
GII76_10395	COG0318	PFAM AMP-dependent synthetase and ligase
GII76_10400	COG1960	acyl-CoA dehydrogenase activity
GII76_10415	COG1649	PFAM Uncharacterised BCR, COG1649
GII76_10425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII76_10425	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII76_10430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII76_10435	COG2027	D-alanyl-D-alanine carboxypeptidase
GII76_10440	COG2017	converts alpha-aldose to the beta-anomer
GII76_10445	COG0534	Mate efflux family protein
GII76_10460	COG0582	viral genome integration into host DNA
GII76_10465	COG0166	Belongs to the GPI family
GII76_10470	COG0405	Gamma-glutamyltransferase
GII76_10475	COG0583	DNA-binding transcription factor activity
GII76_10480	COG0604	alcohol dehydrogenase
GII76_10485	COG0493	'glutamate synthase
GII76_10490	COG0069	glutamate synthase activity
GII76_10490	COG0067	glutamate synthase
GII76_10490	COG0070	glutamate synthase
GII76_10495	COG0583	DNA-binding transcription factor activity
GII76_10500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII76_10505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII76_10515	COG0300	oxidoreductase activity
GII76_10520	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII76_10530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII76_10545	COG2814	Major facilitator Superfamily
GII76_10550	COG1070	Carbohydrate kinase
GII76_10555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII76_10560	COG0243	molybdopterin cofactor binding
GII76_10590	COG5278	phosphoserine phosphatase activity
GII76_10590	COG0840	transmembrane signaling receptor activity
GII76_10595	COG2368	4-hydroxyphenylacetate
GII76_10600	COG4305	rare lipoprotein A
GII76_10605	COG3619	membrane
GII76_10610	COG3866	Pectate lyase
GII76_10615	COG2135	peptidase activity
GII76_10625	COG2140	Oxalate decarboxylase
GII76_10635	COG0456	acetyltransferase
GII76_10655	COG2720	vancomycin resistance protein
GII76_10665	COG3655	Transcriptional regulator
GII76_10670	COG3739	integral membrane protein
GII76_10675	COG0583	DNA-binding transcription factor activity
GII76_10680	COG0697	spore germination
GII76_10690	COG0693	protein deglycase activity
GII76_10695	COG2367	Beta-lactamase
GII76_10720	COG0574	Belongs to the PEP-utilizing enzyme family
GII76_10720	COG3848	Pyruvate phosphate dikinase
GII76_10725	COG0726	polysaccharide deacetylase
GII76_10730	COG2314	TM2 domain
GII76_10735	COG1396	sequence-specific DNA binding
GII76_10855	COG0457	Tetratricopeptide repeat
GII76_10890	COG4282	regulation of fungal-type cell wall biogenesis
GII76_10895	COG1231	oxidoreductase activity
GII76_10900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII76_10905	COG2207	Transcriptional regulator
GII76_10905	COG0662	Cupin 2, conserved barrel domain protein
GII76_10910	COG0456	acetyltransferase
GII76_10915	COG1309	transcriptional regulator
GII76_10920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII76_10925	COG3708	Transcriptional regulator
GII76_10930	COG2378	regulation of single-species biofilm formation
GII76_10940	COG0640	Transcriptional regulator
GII76_10945	COG0741	lytic transglycosylase activity
GII76_10950	COG2322	membrane
GII76_10965	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII76_10970	COG3239	Fatty acid desaturase
GII76_10975	COG4585	Histidine kinase
GII76_10980	COG2197	response regulator
GII76_10985	COG3584	3D domain protein
GII76_10985	COG1388	LysM domain
GII76_10990	COG0514	ATP-dependent DNA helicase (RecQ)
GII76_11000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII76_11005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII76_11020	COG0071	Belongs to the small heat shock protein (HSP20) family
GII76_11045	COG1012	belongs to the aldehyde dehydrogenase family
GII76_11050	COG1657	PFAM Prenyltransferase squalene oxidase
GII76_11055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII76_11060	COG0733	neurotransmitter:sodium symporter activity
GII76_11065	COG0385	Bile acid
GII76_11070	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII76_11075	COG0567	Dehydrogenase, E1 component
GII76_11080	COG4548	von Willebrand factor, type A
GII76_11085	COG0714	Associated with various cellular activities
GII76_11090	COG2032	superoxide dismutase activity
GII76_11095	COG1388	LysM domain
GII76_11095	COG0791	NLP P60 protein
GII76_11100	COG1819	glycosyl
GII76_11105	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII76_11110	COG0534	Mate efflux family protein
GII76_11115	COG1366	Belongs to the anti-sigma-factor antagonist family
GII76_11120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII76_11125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII76_11135	COG2962	Rard protein
GII76_11150	COG2610	gluconate transmembrane transporter activity
GII76_11155	COG1942	4-Oxalocrotonate Tautomerase
GII76_11160	COG1733	regulation of RNA biosynthetic process
GII76_11165	COG0778	Nitroreductase
GII76_11170	COG0400	carboxylic ester hydrolase activity
GII76_11175	COG0346	lactoylglutathione lyase activity
GII76_11185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII76_11190	COG0793	Belongs to the peptidase S41A family
GII76_11190	COG3409	Peptidoglycan-binding domain 1 protein
GII76_11195	COG2226	methyltransferase
GII76_11205	COG1876	peptidase activity
GII76_11210	COG0813	purine-nucleoside phosphorylase activity
GII76_11225	COG0671	phosphoesterase, PA-phosphatase related
GII76_11245	COG4479	Belongs to the UPF0346 family
GII76_11255	COG1509	lysine 2,3-aminomutase activity
GII76_11260	COG0456	acetyltransferase
GII76_11265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII76_11270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII76_11275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII76_11280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII76_11295	COG0456	acetyltransferase
GII76_11300	COG0463	Glycosyl transferase, family 2
GII76_11315	COG4641	Protein conserved in bacteria
GII76_11320	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII76_11325	COG1086	Polysaccharide biosynthesis protein
GII76_11330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII76_11335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII76_11340	COG1846	Transcriptional regulator
GII76_11345	COG0534	Mate efflux family protein
GII76_11355	COG4698	Protein conserved in bacteria
GII76_11360	COG2755	lipolytic protein G-D-S-L family
GII76_11365	COG1999	signal sequence binding
GII76_11375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII76_11380	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII76_11385	COG1272	protein, Hemolysin III
GII76_11390	COG0204	Acyl-transferase
GII76_11395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII76_11400	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII76_11405	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII76_11415	COG2521	methyltransferase
GII76_11415	COG2136	Putative SAM-dependent methyltransferase
GII76_11425	COG0129	dihydroxy-acid dehydratase activity
GII76_11430	COG1413	lyase activity
GII76_11435	COG1418	mRNA catabolic process
GII76_11440	COG0386	Belongs to the glutathione peroxidase family
GII76_11445	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII76_11450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII76_11460	COG1278	Cold shock
GII76_11480	COG0328	RNA-DNA hybrid ribonuclease activity
GII76_11485	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII76_11490	COG0328	RNA-DNA hybrid ribonuclease activity
GII76_11500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII76_11515	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII76_11525	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII76_11530	COG3424	synthase
GII76_11535	COG2233	PERMEase
GII76_11540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII76_11545	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII76_11555	COG0800	Aldolase
GII76_11560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII76_11565	COG1609	Transcriptional regulator
GII76_11570	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII76_11575	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_11580	COG1199	ATP-dependent helicase activity
GII76_11595	COG0116	Belongs to the methyltransferase superfamily
GII76_11610	COG4474	Belongs to the UPF0398 family
GII76_11625	COG3359	exonuclease
GII76_11630	COG1111	helicase
GII76_11630	COG1205	dead DEAH box helicase
GII76_11635	COG2190	(PTS) system
GII76_11640	COG0071	Belongs to the small heat shock protein (HSP20) family
GII76_11675	COG3331	DNA recombination
GII76_11680	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII76_11680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII76_11690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII76_11695	COG3935	DnaD domain protein
GII76_11700	COG0017	Asparaginyl-tRNA synthetase
GII76_11705	COG0436	Aminotransferase
GII76_11710	COG5353	protein conserved in bacteria
GII76_11720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII76_11720	COG1199	ATP-dependent helicase activity
GII76_11725	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII76_11730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII76_11735	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII76_11740	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII76_11740	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII76_11745	COG0617	tRNA 3'-terminal CCA addition
GII76_11750	COG0438	transferase activity, transferring glycosyl groups
GII76_11755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII76_11760	COG1803	Methylglyoxal synthase
GII76_11765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII76_11770	COG1694	Mazg nucleotide pyrophosphohydrolase
GII76_11775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII76_11785	COG4347	Protein of unknown function (DUF1405)
GII76_11790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII76_11790	COG2010	Cytochrome c
GII76_11795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII76_11800	COG0723	plastoquinol--plastocyanin reductase activity
GII76_11810	COG5582	Belongs to the UPF0302 family
GII76_11815	COG0457	Tetratricopeptide repeat
GII76_11820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII76_11825	COG0287	Prephenate dehydrogenase
GII76_11830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GII76_11840	COG0133	tryptophan synthase activity
GII76_11845	COG0135	phosphoribosylanthranilate isomerase activity
GII76_11855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII76_11860	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII76_11865	COG4401	Chorismate mutase type I
GII76_11870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII76_11875	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII76_11880	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII76_11885	COG0105	UTP biosynthetic process
GII76_11890	COG0142	geranyltranstransferase activity
GII76_11895	COG2226	methyltransferase
GII76_11900	COG0142	geranyltranstransferase activity
GII76_11910	COG0302	gtp cyclohydrolase
GII76_11915	COG0776	regulation of translation
GII76_11920	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII76_11935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII76_11940	COG1160	GTP binding
GII76_11965	COG1304	FMN binding
GII76_11970	COG0539	negative regulation of cytoplasmic translation
GII76_11975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII76_11985	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII76_11990	COG2959	enzyme of heme biosynthesis
GII76_11995	COG3409	Peptidoglycan-binding domain 1 protein
GII76_11995	COG3773	Cell wall hydrolase
GII76_12000	COG2339	peptidase activity
GII76_12005	COG0492	ferredoxin-NADP+ reductase activity
GII76_12010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII76_12015	COG4862	establishment of competence for transformation
GII76_12020	COG1408	metallophosphoesterase
GII76_12030	COG1388	LysM domain
GII76_12035	COG1266	CAAX protease self-immunity
GII76_12040	COG0514	ATP-dependent DNA helicase (RecQ)
GII76_12045	COG4955	Helix-turn-helix domain
GII76_12050	COG1141	Ferredoxin
GII76_12055	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII76_12060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII76_12065	COG0710	3-dehydroquinate dehydratase activity
GII76_12075	COG1595	DNA-templated transcription, initiation
GII76_12080	COG5002	protein histidine kinase activity
GII76_12085	COG0745	RESPONSE REGULATOR receiver
GII76_12090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII76_12095	COG1333	cytochrome c biogenesis protein
GII76_12100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII76_12105	COG1187	pseudouridine synthase activity
GII76_12110	COG0700	Nucleoside recognition
GII76_12115	COG2715	membrane protein required for spore maturation
GII76_12120	COG1686	Belongs to the peptidase S11 family
GII76_12130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII76_12135	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII76_12140	COG1547	Domain of unknown function (DUF309)
GII76_12145	COG0456	acetyltransferase
GII76_12150	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII76_12155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII76_12155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII76_12160	COG0307	riboflavin synthase, alpha
GII76_12165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII76_12165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII76_12175	COG0681	Belongs to the peptidase S26 family
GII76_12185	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII76_12210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII76_12215	COG4086	secreted protein
GII76_12220	COG0019	diaminopimelate decarboxylase activity
GII76_12225	COG0697	spore germination
GII76_12240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII76_12260	COG1191	sigma factor activity
GII76_12265	COG2172	sigma factor antagonist activity
GII76_12270	COG1366	Belongs to the anti-sigma-factor antagonist family
GII76_12275	COG1686	Belongs to the peptidase S11 family
GII76_12280	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII76_12285	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII76_12290	COG4974	Belongs to the 'phage' integrase family
GII76_12300	COG0735	belongs to the Fur family
GII76_12305	COG1300	Membrane
GII76_12315	COG0281	malic enzyme
GII76_12320	COG1757	Na H antiporter
GII76_12325	COG1027	Aspartate ammonia-lyase
GII76_12330	COG0252	asparaginase activity
GII76_12335	COG1396	sequence-specific DNA binding
GII76_12340	COG1379	DNA repair
GII76_12345	COG0494	nUDIX hydrolase
GII76_12355	COG0667	Aldo Keto reductase
GII76_12365	COG1073	alpha beta
GII76_12375	COG4918	Iron-sulphur cluster biosynthesis
GII76_12380	COG0456	acetyltransferase
GII76_12380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII76_12385	COG2329	Antibiotic biosynthesis monooxygenase
GII76_12390	COG0456	acetyltransferase
GII76_12400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII76_12410	COG2211	Major facilitator Superfamily
GII76_12415	COG0346	lactoylglutathione lyase activity
GII76_12420	COG1072	(Pantothenic acid kinase))
GII76_12425	COG3048	D-serine ammonia-lyase activity
GII76_12430	COG0300	oxidoreductase activity
GII76_12435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII76_12440	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII76_12445	COG4187	Peptidase family M20/M25/M40
GII76_12450	COG1902	pentaerythritol trinitrate reductase activity
GII76_12455	COG0596	Alpha beta hydrolase
GII76_12465	COG1234	tRNA 3'-trailer cleavage
GII76_12470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII76_12475	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII76_12480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII76_12490	COG0706	membrane insertase activity
GII76_12495	COG3361	conserved protein (COG2071)
GII76_12500	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII76_12505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII76_12510	COG0346	lactoylglutathione lyase activity
GII76_12520	COG1376	ErfK ybiS ycfS ynhG family protein
GII76_12525	COG4129	membrane
GII76_12530	COG1126	abc transporter atp-binding protein
GII76_12535	COG0765	amino acid transport
GII76_12540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII76_12550	COG1597	lipid kinase activity
GII76_12555	COG2814	Major facilitator Superfamily
GII76_12560	COG0789	Transcriptional regulator
GII76_12560	COG4978	Transcriptional regulator
GII76_12565	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII76_12570	COG0022	dehydrogenase e1 component
GII76_12575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII76_12580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII76_12585	COG3426	butyrate kinase activity
GII76_12590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII76_12595	COG0280	phosphate acetyltransferase
GII76_12600	COG3829	transcription factor binding
GII76_12600	COG3290	protein histidine kinase activity
GII76_12610	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII76_12615	COG2079	MmgE PrpD family protein
GII76_12620	COG0372	Belongs to the citrate synthase family
GII76_12625	COG1960	acyl-CoA dehydrogenase activity
GII76_12630	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII76_12635	COG0183	Belongs to the thiolase family
GII76_12640	COG0584	glycerophosphoryl diester phosphodiesterase
GII76_12645	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII76_12660	COG1902	pentaerythritol trinitrate reductase activity
GII76_12665	COG0745	RESPONSE REGULATOR receiver
GII76_12670	COG0750	zinc metalloprotease
GII76_12675	COG0497	DNA recombination
GII76_12680	COG1438	arginine binding
GII76_12685	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII76_12690	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII76_12695	COG0142	geranyltranstransferase activity
GII76_12700	COG1722	exodeoxyribonuclease VII activity
GII76_12705	COG1570	exodeoxyribonuclease VII activity
GII76_12710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII76_12715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII76_12720	COG1302	Protein conserved in bacteria
GII76_12725	COG0439	Biotin carboxylase
GII76_12730	COG0511	ligase activity, forming carbon-carbon bonds
GII76_12770	COG3854	ATPases associated with a variety of cellular activities
GII76_12780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII76_12785	COG0006	proline dipeptidase activity
GII76_12790	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII76_12800	COG3872	metal-dependent enzyme
GII76_12810	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII76_12815	COG1321	iron dependent repressor
GII76_12820	COG0095	Lipoate-protein ligase
GII76_12825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII76_12830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII76_12835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII76_12840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII76_12845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII76_12860	COG1396	sequence-specific DNA binding
GII76_12870	COG0681	Belongs to the peptidase S26 family
GII76_12895	COG4940	Competence protein ComGF
GII76_12905	COG4970	Tfp pilus assembly protein FimT
GII76_12910	COG4537	Required for transformation and DNA binding
GII76_12915	COG1459	type II secretion system
GII76_12920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII76_12925	COG0517	IMP dehydrogenase activity
GII76_12930	COG0598	Magnesium transport protein CorA
GII76_12935	COG1253	flavin adenine dinucleotide binding
GII76_12940	COG1366	Belongs to the anti-sigma-factor antagonist family
GII76_12950	COG1393	Belongs to the ArsC family
GII76_12960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII76_12970	COG0011	TIGRFAM Protein of
GII76_12980	COG2866	Carboxypeptidase
GII76_12985	COG1368	sulfuric ester hydrolase activity
GII76_12990	COG1940	carbohydrate kinase activity
GII76_12995	COG4483	Protein conserved in bacteria
GII76_13000	COG0705	Rhomboid family
GII76_13000	COG0457	Tetratricopeptide repeat
GII76_13010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII76_13015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII76_13020	COG0438	transferase activity, transferring glycosyl groups
GII76_13035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII76_13040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII76_13045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII76_13050	COG0581	inorganic phosphate transmembrane transporter activity
GII76_13055	COG0573	inorganic phosphate transmembrane transporter activity
GII76_13060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII76_13070	COG0477	Major facilitator Superfamily
GII76_13075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII76_13080	COG2839	Protein conserved in bacteria
GII76_13085	COG5521	maltodextrose utilization protein MalA
GII76_13090	COG1388	LysM domain
GII76_13095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII76_13100	COG4709	membrane
GII76_13105	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII76_13110	COG0735	belongs to the Fur family
GII76_13115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII76_13125	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII76_13130	COG0513	Belongs to the DEAD box helicase family
GII76_13140	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII76_13145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII76_13150	COG2384	SAM-dependent methyltransferase
GII76_13155	COG2010	Cytochrome c
GII76_13160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII76_13165	COG0358	DNA primase activity
GII76_13170	COG1671	Belongs to the UPF0178 family
GII76_13175	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII76_13180	COG0517	IMP dehydrogenase activity
GII76_13185	COG0751	glycine-tRNA ligase activity
GII76_13190	COG0752	glycyl-tRNA synthetase alpha subunit
GII76_13195	COG1381	Involved in DNA repair and RecF pathway recombination
GII76_13205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII76_13210	COG0295	cytidine deaminase activity
GII76_13215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII76_13220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII76_13225	COG1480	7TM receptor with intracellular HD hydrolase
GII76_13230	COG1702	phosphate starvation-inducible protein PhoH
GII76_13235	COG0561	phosphatase activity
GII76_13250	COG4864	UPF0365 protein
GII76_13255	COG1030	water channel activity
GII76_13260	COG1610	YqeY-like protein
GII76_13265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GII76_13270	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII76_13275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII76_13280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII76_13285	COG2264	protein methyltransferase activity
GII76_13290	COG0484	heat shock protein binding
GII76_13295	COG0443	Heat shock 70 kDa protein
GII76_13300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII76_13305	COG1420	regulation of RNA biosynthetic process
GII76_13310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII76_13315	COG0481	GTPase activity
GII76_13325	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII76_13330	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII76_13335	COG0268	Binds directly to 16S ribosomal RNA
GII76_13340	COG1466	dna polymerase III delta subunit
GII76_13355	COG0658	competence protein
GII76_13355	COG2333	competence protein COMEC
GII76_13360	COG2131	deaminase
GII76_13365	COG1555	photosystem II stabilization
GII76_13365	COG1596	polysaccharide export
GII76_13370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII76_13375	COG2226	methyltransferase
GII76_13380	COG0799	negative regulation of ribosome biogenesis
GII76_13385	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII76_13390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII76_13395	COG1534	Rna-binding protein
GII76_13400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII76_13405	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII76_13410	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII76_13420	COG2755	lipolytic protein G-D-S-L family
GII76_13425	COG3409	Peptidoglycan-binding domain 1 protein
GII76_13425	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII76_13430	COG0398	Pfam SNARE associated Golgi protein
GII76_13445	COG3209	COG3209 Rhs family protein
GII76_13455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII76_13460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII76_13465	COG0798	PFAM Bile acid sodium symporter
GII76_13470	COG0346	lactoylglutathione lyase activity
GII76_13475	COG0640	Transcriptional regulator
GII76_13480	COG3403	YqcI/YcgG family
GII76_13500	COG0604	alcohol dehydrogenase
GII76_13525	COG0457	Tetratricopeptide repeat
GII76_13540	COG5444	nuclease activity
GII76_13565	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII76_13565	COG3409	Peptidoglycan-binding domain 1 protein
GII76_13570	COG4824	toxin secretion phage lysis holin
GII76_13600	COG3778	Protein conserved in bacteria
GII76_13605	COG3299	homolog of phage Mu protein gp47
GII76_13610	COG3628	GPW Gp25 family protein
GII76_13620	COG4193	domain, Protein
GII76_13625	COG1652	LysM domain
GII76_13630	COG3953	SLT domain
GII76_13630	COG5280	Phage tail tape measure protein TP901
GII76_13690	COG4653	Phage capsid family
GII76_13695	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII76_13705	COG2369	cell adhesion
GII76_13710	COG5518	Phage portal protein
GII76_13715	COG1783	phage Terminase large subunit
GII76_13720	COG5484	DNA packaging
GII76_13730	COG3677	Transposase
GII76_13745	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GII76_13755	COG1484	DNA-dependent DNA replication
GII76_13760	COG3935	DnaD domain protein
GII76_13765	COG3723	Recombinational DNA repair protein, rece pathway
GII76_13770	COG5377	YqaJ viral recombinase family
GII76_13800	COG1476	TRANSCRIPTIONal
GII76_13805	COG3620	sequence-specific DNA binding
GII76_13815	COG0563	adenylate kinase activity
GII76_13820	COG2856	Zn peptidase
GII76_13835	COG0642	Histidine kinase
GII76_13835	COG5002	protein histidine kinase activity
GII76_13840	COG0745	RESPONSE REGULATOR receiver
GII76_13845	COG2311	Membrane
GII76_13855	COG0454	-acetyltransferase
GII76_13860	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII76_13870	COG0730	response to heat
GII76_13875	COG0425	Belongs to the sulfur carrier protein TusA family
GII76_13880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII76_13880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII76_13890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII76_13890	COG0425	Belongs to the sulfur carrier protein TusA family
GII76_13900	COG1937	Protein conserved in bacteria
GII76_13905	COG0662	Cupin 2, conserved barrel domain protein
GII76_13915	COG4978	Transcriptional regulator
GII76_13915	COG0789	Transcriptional regulator
GII76_13920	COG2814	Major facilitator Superfamily
GII76_13925	COG0456	acetyltransferase
GII76_13930	COG1253	flavin adenine dinucleotide binding
GII76_13940	COG0697	spore germination
GII76_13945	COG0583	DNA-binding transcription factor activity
GII76_13950	COG2072	flavoprotein involved in K transport
GII76_13955	COG1230	cation diffusion facilitator family transporter
GII76_13960	COG1942	4-Oxalocrotonate Tautomerase
GII76_13965	COG0583	DNA-binding transcription factor activity
GII76_13975	COG1114	Component of the transport system for branched-chain amino acids
GII76_13980	COG1687	branched-chain amino acid
GII76_13985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII76_13990	COG1522	sequence-specific DNA binding
GII76_14000	COG2124	cytochrome p450
GII76_14005	COG1335	isochorismatase
GII76_14015	COG2318	DinB family
GII76_14025	COG2070	2-Nitropropane dioxygenase
GII76_14030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII76_14040	COG2186	Transcriptional regulator
GII76_14055	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_14060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII76_14065	COG3959	Transketolase, thiamine diphosphate binding domain
GII76_14075	COG0789	Transcriptional regulator
GII76_14075	COG4978	Transcriptional regulator
GII76_14080	COG2315	Protein conserved in bacteria
GII76_14090	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII76_14095	COG1595	DNA-templated transcription, initiation
GII76_14100	COG0667	Aldo Keto reductase
GII76_14105	COG2851	Citrate transporter
GII76_14110	COG0583	DNA-binding transcription factor activity
GII76_14115	COG2828	Protein conserved in bacteria
GII76_14120	COG3409	Peptidoglycan-binding domain 1 protein
GII76_14125	COG5566	PFAM Mor transcription activator
GII76_14130	COG0596	Alpha beta hydrolase
GII76_14135	COG4991	sh3 domain protein
GII76_14140	COG4991	sh3 domain protein
GII76_14150	COG0346	lactoylglutathione lyase activity
GII76_14160	COG5577	PFAM Coat F domain
GII76_14165	COG1063	alcohol dehydrogenase
GII76_14175	COG5577	PFAM Coat F domain
GII76_14180	COG0789	Transcriptional regulator
GII76_14190	COG1064	alcohol dehydrogenase
GII76_14195	COG0693	protein deglycase activity
GII76_14200	COG1621	beta-fructofuranosidase activity
GII76_14205	COG3716	PTS system mannose fructose sorbose family IID component
GII76_14210	COG3715	PTS system
GII76_14215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_14220	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII76_14225	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII76_14225	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII76_14235	COG1113	amino acid transport
GII76_14240	COG1280	lysine exporter protein (LysE YggA)
GII76_14245	COG1378	Sugar-specific transcriptional regulator TrmB
GII76_14250	COG1595	DNA-templated transcription, initiation
GII76_14270	COG2124	cytochrome p450
GII76_14270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII76_14275	COG1309	transcriptional regulator
GII76_14280	COG2226	methyltransferase
GII76_14295	COG2116	formate transmembrane transporter activity
GII76_14300	COG5609	conserved protein (DUF2294)
GII76_14305	COG3383	formate dehydrogenase (NAD+) activity
GII76_14310	COG2427	Protein of unknown function (DUF1641)
GII76_14320	COG0626	cystathionine gamma-synthase activity
GII76_14325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII76_14330	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII76_14335	COG2226	methyltransferase
GII76_14350	COG0768	penicillin binding
GII76_14355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII76_14360	COG0572	uridine kinase
GII76_14380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII76_14385	COG3906	Belongs to the UPF0473 family
GII76_14390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII76_14395	COG4472	Bacterial protein of unknown function (DUF965)
GII76_14400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII76_14405	COG0628	permease
GII76_14410	COG1126	abc transporter atp-binding protein
GII76_14415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII76_14420	COG0765	amino acid transport
GII76_14425	COG0765	amino acid transport
GII76_14440	COG3881	PFAM PRC-barrel domain
GII76_14445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII76_14450	COG0457	Tetratricopeptide repeat
GII76_14455	COG0482	sulfurtransferase activity
GII76_14460	COG1104	cysteine desulfurase activity
GII76_14465	COG1959	2 iron, 2 sulfur cluster binding
GII76_14470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII76_14475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII76_14485	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII76_14490	COG0124	histidyl-tRNA synthetase
GII76_14500	COG4991	sh3 domain protein
GII76_14500	COG3103	Sh3 type 3 domain protein
GII76_14500	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII76_14505	COG1490	D-aminoacyl-tRNA deacylase activity
GII76_14510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII76_14515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII76_14520	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII76_14520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII76_14525	COG5416	Lipopolysaccharide assembly protein A domain
GII76_14530	COG0490	domain, Protein
GII76_14535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII76_14535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII76_14545	COG2244	polysaccharide biosynthetic process
GII76_14550	COG2323	membrane
GII76_14560	COG1862	Preprotein translocase
GII76_14565	COG0343	queuine tRNA-ribosyltransferase activity
GII76_14570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII76_14580	COG2255	four-way junction helicase activity
GII76_14585	COG0632	four-way junction helicase activity
GII76_14595	COG2814	Major facilitator Superfamily
GII76_14600	COG0673	inositol 2-dehydrogenase activity
GII76_14605	COG2112	serine threonine protein kinase
GII76_14625	COG1115	amino acid carrier protein
GII76_14630	COG0217	transcriptional regulatory protein
GII76_14640	COG1388	LysM domain
GII76_14645	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII76_14650	COG0157	Belongs to the NadC ModD family
GII76_14655	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII76_14660	COG1104	cysteine desulfurase activity
GII76_14665	COG1827	regulation of RNA biosynthetic process
GII76_14670	COG0077	Prephenate dehydratase
GII76_14675	COG4492	Belongs to the UPF0735 family
GII76_14680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII76_14685	COG3290	protein histidine kinase activity
GII76_14695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII76_14700	COG2868	ribosomal protein
GII76_14705	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII76_14710	COG1994	Peptidase M50
GII76_14715	COG0739	heme binding
GII76_14720	COG2894	cell division
GII76_14725	COG0850	regulation of cytokinetic process
GII76_14730	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII76_14735	COG1792	Involved in formation and maintenance of cell shape
GII76_14740	COG1077	Cell shape determining protein MreB Mrl
GII76_14745	COG2003	Belongs to the UPF0758 family
GII76_14750	COG0424	maF-like protein
GII76_14760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII76_14765	COG0285	dihydrofolate synthase activity
GII76_14770	COG0525	valine-tRNA ligase activity
GII76_14780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII76_14785	COG1388	LysM domain
GII76_14790	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII76_14795	COG0113	porphobilinogen synthase activity
GII76_14800	COG1587	Uroporphyrinogen-III synthase
GII76_14805	COG0181	hydroxymethylbilane synthase activity
GII76_14810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII76_14815	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII76_14825	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII76_14830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII76_14835	COG1067	ATP-dependent peptidase activity
GII76_14835	COG0470	DNA polymerase III
GII76_14840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII76_14845	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII76_14850	COG1477	protein flavinylation
GII76_14850	COG0457	Tetratricopeptide repeat
GII76_14855	COG0066	3-isopropylmalate dehydratase activity
GII76_14860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII76_14865	COG0473	3-isopropylmalate dehydrogenase activity
GII76_14870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII76_14875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII76_14880	COG0440	acetolactate synthase activity
GII76_14885	COG0028	Belongs to the TPP enzyme family
GII76_14895	COG0454	-acetyltransferase
GII76_14900	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII76_14910	COG0622	Phosphoesterase
GII76_14915	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII76_14920	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII76_14925	COG5401	PFAM Sporulation and spore germination
GII76_14930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII76_14935	COG1846	Transcriptional regulator
GII76_14940	COG2197	response regulator
GII76_14945	COG0824	Thioesterase
GII76_14950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII76_14955	COG1053	succinate dehydrogenase
GII76_14960	COG2009	succinate dehydrogenase
GII76_14965	COG1719	4-vinyl reductase, 4VR
GII76_14970	COG0527	aspartate kinase activity
GII76_14975	COG0322	excinuclease ABC activity
GII76_14980	COG3118	belongs to the thioredoxin family
GII76_14985	COG3534	alpha-L-arabinofuranosidase
GII76_14990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII76_14995	COG2086	electron transfer activity
GII76_15000	COG1024	Enoyl-CoA hydratase
GII76_15005	COG1309	transcriptional regulator
GII76_15010	COG0318	PFAM AMP-dependent synthetase and ligase
GII76_15015	COG3766	membrane
GII76_15020	COG1193	negative regulation of DNA recombination
GII76_15025	COG1796	DNA polymerase
GII76_15025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII76_15030	COG1286	toxin biosynthetic process
GII76_15035	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII76_15040	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII76_15045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII76_15045	COG0072	phenylalanine-tRNA ligase activity
GII76_15050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII76_15060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII76_15070	COG3835	regulator
GII76_15075	COG0277	FAD linked oxidase domain protein
GII76_15080	COG0247	lactate metabolic process
GII76_15095	COG1966	Carbon starvation protein
GII76_15100	COG3534	alpha-L-arabinofuranosidase
GII76_15105	COG0395	ABC-type sugar transport system, permease component
GII76_15110	COG1175	transmembrane transport
GII76_15115	COG1653	transport
GII76_15120	COG0371	Dehydrogenase
GII76_15125	COG0647	UMP catabolic process
GII76_15130	COG0235	Class ii aldolase
GII76_15135	COG1069	ribulokinase activity
GII76_15140	COG2160	L-arabinose isomerase activity
GII76_15145	COG3507	Belongs to the glycosyl hydrolase 43 family
GII76_15150	COG1363	Peptidase, m42
GII76_15160	COG3326	Membrane
GII76_15165	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII76_15170	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII76_15175	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII76_15185	COG1346	cytolysis
GII76_15190	COG1380	Effector of murein hydrolase LrgA
GII76_15195	COG3279	Response regulator of the LytR AlgR family
GII76_15200	COG3275	phosphorelay sensor kinase activity
GII76_15210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII76_15220	COG0398	Pfam SNARE associated Golgi protein
GII76_15225	COG1484	DNA-dependent DNA replication
GII76_15230	COG3611	Membrane attachment protein
GII76_15235	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII76_15240	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII76_15245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII76_15250	COG1733	regulation of RNA biosynthetic process
GII76_15255	COG2814	Major facilitator Superfamily
GII76_15260	COG0656	L-ascorbic acid biosynthetic process
GII76_15265	COG0237	dephospho-CoA kinase activity
GII76_15270	COG1971	Probably functions as a manganese efflux pump
GII76_15275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII76_15280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII76_15280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII76_15285	COG5002	protein histidine kinase activity
GII76_15290	COG0745	RESPONSE REGULATOR receiver
GII76_15295	COG0039	L-malate dehydrogenase activity
GII76_15300	COG0538	isocitrate dehydrogenase activity
GII76_15305	COG0372	Belongs to the citrate synthase family
GII76_15310	COG2707	UPF0756 membrane protein
GII76_15315	COG0628	permease
GII76_15320	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII76_15325	COG0469	pyruvate kinase activity
GII76_15330	COG0205	6-phosphofructokinase activity
GII76_15335	COG0825	malonyl-CoA metabolic process
GII76_15340	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII76_15345	COG0281	malic enzyme
GII76_15350	COG0587	DNA-directed DNA polymerase activity
GII76_15370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII76_15380	COG4109	DRTGG domain
GII76_15385	COG0730	response to heat
GII76_15390	COG1473	amidohydrolase
GII76_15395	COG0196	riboflavin kinase activity
GII76_15400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII76_15405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII76_15410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII76_15415	COG1126	abc transporter atp-binding protein
GII76_15420	COG0765	amino acid transport
GII76_15425	COG0765	amino acid transport
GII76_15430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII76_15435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII76_15440	COG0454	-acetyltransferase
GII76_15445	COG0583	DNA-binding transcription factor activity
GII76_15450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII76_15455	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_15465	COG0165	Argininosuccinate lyase
GII76_15470	COG0137	argininosuccinate synthase activity
GII76_15475	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII76_15480	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII76_15490	COG0827	DNA restriction-modification system
GII76_15495	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII76_15500	COG3874	Sporulation protein YtfJ
GII76_15510	COG1714	RDD family
GII76_15515	COG0616	signal peptide processing
GII76_15520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII76_15525	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII76_15530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII76_15540	COG0301	tRNA thio-modification
GII76_15545	COG1104	cysteine desulfurase activity
GII76_15550	COG1114	Component of the transport system for branched-chain amino acids
GII76_15555	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII76_15560	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII76_15565	COG1309	transcriptional regulator
GII76_15570	COG1956	GAF domain-containing protein
GII76_15575	COG2203	Gaf domain
GII76_15575	COG2199	diguanylate cyclase activity
GII76_15585	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII76_15590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII76_15595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII76_15600	COG0454	-acetyltransferase
GII76_15605	COG0517	IMP dehydrogenase activity
GII76_15610	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII76_15615	COG1360	Flagellar Motor Protein
GII76_15620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII76_15625	COG1609	Transcriptional regulator
GII76_15630	COG1605	Chorismate mutase
GII76_15630	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII76_15635	COG3118	belongs to the thioredoxin family
GII76_15640	COG4980	gas vesicle protein
GII76_15645	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII76_15650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII76_15655	COG1674	ftsk spoiiie
GII76_15660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII76_15665	COG4848	Belongs to the UPF0354 family
GII76_15670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII76_15685	COG1363	Peptidase, m42
GII76_15690	COG5584	Small secreted protein
GII76_15695	COG0281	malic enzyme
GII76_15700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII76_15705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII76_15715	COG0510	thiamine kinase activity
GII76_15720	COG1523	belongs to the glycosyl hydrolase 13 family
GII76_15725	COG1597	lipid kinase activity
GII76_15735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII76_15740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII76_15745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII76_15750	COG2252	PERMEase
GII76_15755	COG4473	ABC transporter
GII76_15760	COG1131	(ABC) transporter
GII76_15765	COG1349	DNA-binding transcription factor activity
GII76_15770	COG1187	pseudouridine synthase activity
GII76_15775	COG2244	polysaccharide biosynthetic process
GII76_15780	COG2081	HI0933 family
GII76_15785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII76_15795	COG5578	integral membrane protein
GII76_15800	COG0673	inositol 2-dehydrogenase activity
GII76_15805	COG1653	transport
GII76_15810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII76_15815	COG4209	transmembrane transport
GII76_15820	COG2207	Transcriptional regulator
GII76_15825	COG1653	transport
GII76_15830	COG0395	ABC-type sugar transport system, permease component
GII76_15835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII76_15840	COG2124	cytochrome p450
GII76_15845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII76_15855	COG0156	8-amino-7-oxononanoate synthase activity
GII76_15860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII76_15870	COG1073	alpha beta
GII76_15895	COG1486	melibiose metabolic process
GII76_15900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII76_15905	COG0495	leucyl-tRNA aminoacylation
GII76_15915	COG1366	Belongs to the anti-sigma-factor antagonist family
GII76_15915	COG2202	Pas domain
GII76_15920	COG2814	Major facilitator Superfamily
GII76_15925	COG2433	Pfam Transposase IS66
GII76_15930	COG0577	efflux transmembrane transporter activity
GII76_15935	COG1136	(ABC) transporter
GII76_15940	COG2205	protein histidine kinase activity
GII76_15945	COG0745	RESPONSE REGULATOR receiver
GII76_15950	COG0577	efflux transmembrane transporter activity
GII76_15955	COG1136	(ABC) transporter
GII76_15970	COG1131	(ABC) transporter
GII76_15975	COG1725	Transcriptional regulator
GII76_15990	COG1242	4 iron, 4 sulfur cluster binding
GII76_15995	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII76_16005	COG2267	carboxylic ester hydrolase activity
GII76_16010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII76_16015	COG1113	amino acid transport
GII76_16020	COG0367	asparagine synthase
GII76_16025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII76_16030	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII76_16040	COG1506	peptidase
GII76_16045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII76_16050	COG1116	anion transmembrane transporter activity
GII76_16055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII76_16060	COG0494	nUDIX hydrolase
GII76_16065	COG4824	toxin secretion phage lysis holin
GII76_16070	COG0783	Belongs to the Dps family
GII76_16085	COG1854	S-ribosylhomocysteine lyase activity
GII76_16090	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII76_16095	COG0288	reversible hydration of carbon dioxide
GII76_16100	COG0254	rRNA binding
GII76_16105	COG1271	oxidase subunit
GII76_16110	COG1294	oxidase, subunit
GII76_16120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII76_16125	COG1321	iron dependent repressor
GII76_16125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII76_16130	COG1121	(ABC) transporter
GII76_16135	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII76_16140	COG4948	Mandelate Racemase Muconate Lactonizing
GII76_16145	COG0318	PFAM AMP-dependent synthetase and ligase
GII76_16150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII76_16155	COG0596	Alpha beta hydrolase
GII76_16160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII76_16165	COG1169	isochorismate synthase
GII76_16170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII76_16175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII76_16180	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII76_16185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII76_16190	COG0438	transferase activity, transferring glycosyl groups
GII76_16200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII76_16205	COG0438	transferase activity, transferring glycosyl groups
GII76_16210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII76_16215	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GII76_16220	COG0058	SHG alpha-glucan phosphorylase activity
GII76_16225	COG0297	glycogen (starch) synthase activity
GII76_16230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII76_16235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII76_16240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII76_16365	COG3859	Proton-coupled thiamine transporter YuaJ
GII76_16370	COG1247	-acetyltransferase
GII76_16375	COG2268	Band 7 protein
GII76_16380	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII76_16385	COG2318	DinB family
GII76_16395	COG1454	alcohol dehydrogenase
GII76_16405	COG1510	regulation of RNA biosynthetic process
GII76_16415	COG0569	domain protein
GII76_16420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII76_16425	COG4682	membrane
GII76_16430	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII76_16435	COG0477	Major facilitator Superfamily
GII76_16440	COG5553	Cysteine dioxygenase type I
GII76_16450	COG1968	undecaprenyl-diphosphatase activity
GII76_16455	COG0628	permease
GII76_16460	COG0673	inositol 2-dehydrogenase activity
GII76_16465	COG4806	L-rhamnose isomerase
GII76_16470	COG3254	rhamnose metabolic process
GII76_16475	COG1070	Carbohydrate kinase
GII76_16480	COG1349	DNA-binding transcription factor activity
GII76_16485	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_16485	COG3347	Dehydrogenase
GII76_16490	COG0840	transmembrane signaling receptor activity
GII76_16495	COG0840	transmembrane signaling receptor activity
GII76_16500	COG0840	transmembrane signaling receptor activity
GII76_16505	COG0840	transmembrane signaling receptor activity
GII76_16520	COG0432	Pfam Uncharacterised protein family UPF0047
GII76_16530	COG0366	Alpha amylase catalytic
GII76_16535	COG1253	flavin adenine dinucleotide binding
GII76_16540	COG2738	Putative neutral zinc metallopeptidase
GII76_16555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII76_16570	COG0166	Belongs to the GPI family
GII76_16575	COG1979	alcohol dehydrogenase
GII76_16580	COG1979	alcohol dehydrogenase
GII76_16585	COG2155	Conserved Protein
GII76_16590	COG1098	S1 RNA binding domain
GII76_16595	COG0436	Aminotransferase
GII76_16600	COG1522	sequence-specific DNA binding
GII76_16605	COG2267	carboxylic ester hydrolase activity
GII76_16615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII76_16620	COG2205	protein histidine kinase activity
GII76_16630	COG5018	Exonuclease
GII76_16640	COG2814	Major facilitator Superfamily
GII76_16645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII76_16650	COG3011	Protein conserved in bacteria
GII76_16660	COG3290	protein histidine kinase activity
GII76_16665	COG4565	transcriptional regulatory protein
GII76_16690	COG3493	citrate carrier protein
GII76_16700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII76_16700	COG2111	Na H antiporter
GII76_16705	COG2111	Na H antiporter
GII76_16710	COG1006	Multisubunit Na H antiporter MnhC subunit
GII76_16715	COG0651	ATP synthesis coupled electron transport
GII76_16720	COG1863	multisubunit Na H antiporter MnhE subunit
GII76_16725	COG2212	antiporter activity
GII76_16730	COG1320	monovalent cation:proton antiporter activity
GII76_16735	COG2050	protein possibly involved in aromatic compounds catabolism
GII76_16740	COG2197	response regulator
GII76_16745	COG4585	Histidine kinase
GII76_16755	COG0142	geranyltranstransferase activity
GII76_16775	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII76_16780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII76_16785	COG1335	isochorismatase
GII76_16790	COG5506	Protein of unknown function (DUF1694)
GII76_16805	COG0628	permease
GII76_16820	COG1418	mRNA catabolic process
GII76_16825	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_16835	COG1511	domain protein
GII76_16840	COG1674	ftsk spoiiie
GII76_16840	COG0433	COG0433 Predicted ATPase
GII76_16845	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII76_16850	COG5417	Belongs to the EsaB family
GII76_16855	COG4842	Belongs to the WXG100 family
GII76_16860	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII76_16860	COG2508	Transcriptional regulator
GII76_16865	COG0686	Belongs to the AlaDH PNT family
GII76_16870	COG5634	Uncharacterized conserved protein (DUF2278)
GII76_16875	COG3251	PFAM MbtH domain protein
GII76_16880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII76_16885	COG3433	isochorismatase activity
GII76_16885	COG1535	isochorismatase
GII76_16890	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII76_16895	COG1169	isochorismate synthase
GII76_16900	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_16905	COG2819	hydrolase of the alpha beta superfamily
GII76_16910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII76_16915	COG1268	BioY protein
GII76_16920	COG2056	Na+-H+ antiporter family
GII76_16925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII76_16930	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII76_16935	COG3584	3D domain protein
GII76_16950	COG1252	NADH dehydrogenase
GII76_16955	COG0492	ferredoxin-NADP+ reductase activity
GII76_16965	COG0516	GMP reductase activity
GII76_16970	COG2808	Putative FMN-binding domain
GII76_16975	COG0456	acetyltransferase
GII76_16980	COG0316	Belongs to the HesB IscA family
GII76_16985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII76_16990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII76_16995	COG4844	belongs to the
GII76_17000	COG1252	NADH dehydrogenase
GII76_17005	COG4837	Protein of unknown function (DUF1462)
GII76_17010	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII76_17015	COG4946	Tricorn protease homolog
GII76_17015	COG0823	Involved in the tonB-independent uptake of proteins
GII76_17015	COG1506	peptidase
GII76_17020	COG0083	homoserine kinase activity
GII76_17025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII76_17030	COG0460	homoserine dehydrogenase
GII76_17035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII76_17040	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII76_17045	COG0647	UMP catabolic process
GII76_17050	COG2445	Protein of unknown function DUF86
GII76_17055	COG4470	Protein conserved in bacteria
GII76_17065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII76_17070	COG0739	heme binding
GII76_17080	COG3377	Domain of unknown function (DUF1805)
GII76_17085	COG0737	Belongs to the 5'-nucleotidase family
GII76_17090	COG0730	response to heat
GII76_17095	COG1801	Protein of unknown function DUF72
GII76_17105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII76_17110	COG2508	Transcriptional regulator
GII76_17115	COG2233	PERMEase
GII76_17120	COG2233	PERMEase
GII76_17125	COG3648	Uricase
GII76_17125	COG3195	allantoin biosynthetic process
GII76_17130	COG2351	hydroxyisourate hydrolase activity
GII76_17140	COG2080	2 iron, 2 sulfur cluster binding
GII76_17145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII76_17150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII76_17155	COG2068	MobA-Related Protein
GII76_17160	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII76_17165	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII76_17170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII76_17180	COG2356	endonuclease I
GII76_17185	COG3842	ATPase activity
GII76_17190	COG2188	Transcriptional regulator
GII76_17195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII76_17200	COG0395	ABC-type sugar transport system, permease component
GII76_17205	COG1175	transmembrane transport
GII76_17210	COG1653	transport
GII76_17215	COG2222	sugar isomerase
GII76_17220	COG0322	excinuclease ABC activity
GII76_17225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII76_17240	COG0346	lactoylglutathione lyase activity
GII76_17245	COG0640	Transcriptional regulator
GII76_17250	COG0719	Fe-S assembly protein
GII76_17255	COG0822	iron-sulfur transferase activity
GII76_17260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII76_17265	COG0719	Fe-S assembly protein
GII76_17270	COG0396	ATPase activity
GII76_17280	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII76_17285	COG1464	Belongs to the NlpA lipoprotein family
GII76_17290	COG2011	ABC-type metal ion transport system permease component
GII76_17295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII76_17305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII76_17310	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII76_17320	COG0509	glycine decarboxylation via glycine cleavage system
GII76_17325	COG1393	Belongs to the ArsC family
GII76_17330	COG1960	acyl-CoA dehydrogenase activity
GII76_17335	COG0183	Belongs to the thiolase family
GII76_17340	COG1024	Enoyl-CoA hydratase
GII76_17340	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII76_17350	COG0506	proline dehydrogenase activity
GII76_17360	COG5577	PFAM Coat F domain
GII76_17365	COG1846	Transcriptional regulator
GII76_17370	COG0477	Major facilitator Superfamily
GII76_17375	COG1942	4-Oxalocrotonate Tautomerase
GII76_17380	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_17385	COG0583	DNA-binding transcription factor activity
GII76_17395	COG1120	ATPase activity
GII76_17410	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_17415	COG0783	Belongs to the Dps family
GII76_17420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII76_17425	COG0745	RESPONSE REGULATOR receiver
GII76_17430	COG2770	Histidine kinase
GII76_17430	COG2205	protein histidine kinase activity
GII76_17440	COG1309	transcriptional regulator
GII76_17445	COG0114	fumarate hydratase activity
GII76_17455	COG0697	spore germination
GII76_17460	COG0814	amino acid
GII76_17470	COG2197	response regulator
GII76_17475	COG4585	Histidine kinase
GII76_17480	COG4758	membrane
GII76_17485	COG3595	metallopeptidase activity
GII76_17490	COG1842	Phage shock protein A
GII76_17495	COG4758	membrane
GII76_17500	COG2814	Major facilitator Superfamily
GII76_17505	COG2096	Adenosyltransferase
GII76_17510	COG1120	ATPase activity
GII76_17515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII76_17520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII76_17525	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_17530	COG3386	PFAM SMP-30 Gluconolaconase
GII76_17535	COG2205	protein histidine kinase activity
GII76_17540	COG0745	RESPONSE REGULATOR receiver
GII76_17550	COG1191	sigma factor activity
GII76_17560	COG2140	Oxalate decarboxylase
GII76_17570	COG0577	efflux transmembrane transporter activity
GII76_17575	COG1136	(ABC) transporter
GII76_17580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII76_17585	COG1120	ATPase activity
GII76_17590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII76_17595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII76_17600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII76_17605	COG0531	amino acid
GII76_17615	COG1988	membrane-bound metal-dependent
GII76_17620	COG1368	sulfuric ester hydrolase activity
GII76_17625	COG1910	domain protein
GII76_17630	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII76_17635	COG4149	molybdate abc transporter
GII76_17640	COG0656	L-ascorbic acid biosynthetic process
GII76_17650	COG0025	NhaP-type Na H and K H
GII76_17655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII76_17660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII76_17665	COG3973	AAA domain
GII76_17675	COG2860	membrane
GII76_17680	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII76_17685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII76_17690	COG2217	Heavy metal translocating P-type atpase
GII76_17695	COG2217	Heavy metal translocating P-type atpase
GII76_17700	COG2608	mercury ion transmembrane transporter activity
GII76_17705	COG1937	Protein conserved in bacteria
GII76_17710	COG0673	inositol 2-dehydrogenase activity
GII76_17715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII76_17720	COG1289	transmembrane transporter activity
GII76_17730	COG2076	Multidrug Resistance protein
GII76_17735	COG1309	transcriptional regulator
GII76_17740	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_17750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII76_17755	COG0557	exoribonuclease II activity
GII76_17760	COG1647	Serine aminopeptidase, S33
GII76_17765	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII76_17770	COG0596	Alpha beta hydrolase
GII76_17775	COG1476	TRANSCRIPTIONal
GII76_17780	COG1396	sequence-specific DNA binding
GII76_17785	COG1396	sequence-specific DNA binding
GII76_17790	COG1733	regulation of RNA biosynthetic process
GII76_17795	COG0840	transmembrane signaling receptor activity
GII76_17800	COG1174	glycine betaine transport
GII76_17805	COG1732	Glycine betaine
GII76_17810	COG1174	glycine betaine transport
GII76_17815	COG1125	glycine betaine transport
GII76_17815	COG0517	IMP dehydrogenase activity
GII76_17820	COG1510	regulation of RNA biosynthetic process
GII76_17825	COG1174	glycine betaine transport
GII76_17830	COG1732	Glycine betaine
GII76_17835	COG1174	glycine betaine transport
GII76_17840	COG1125	glycine betaine transport
GII76_17840	COG0517	IMP dehydrogenase activity
GII76_17845	COG1510	regulation of RNA biosynthetic process
GII76_17850	COG2095	MarC family integral membrane protein
GII76_17860	COG3064	Membrane
GII76_17865	COG4640	response to antibiotic
GII76_17870	COG0456	acetyltransferase
GII76_17875	COG0148	phosphopyruvate hydratase activity
GII76_17880	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII76_17885	COG0149	triose-phosphate isomerase activity
GII76_17890	COG0126	phosphoglycerate kinase activity
GII76_17895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII76_17900	COG2390	Transcriptional regulator
GII76_17905	COG2814	Major facilitator Superfamily
GII76_17910	COG1609	Transcriptional regulator
GII76_17915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII76_17925	COG0583	DNA-binding transcription factor activity
GII76_17930	COG0697	spore germination
GII76_17935	COG1113	amino acid transport
GII76_17940	COG3858	chitin binding
GII76_17945	COG1556	Lactate utilization protein
GII76_17950	COG1139	Iron-sulfur cluster binding protein
GII76_17955	COG0247	lactate metabolic process
GII76_17960	COG2197	response regulator
GII76_17965	COG4585	Histidine kinase
GII76_17970	COG0842	Transport permease protein
GII76_17975	COG1131	(ABC) transporter
GII76_17980	COG0596	Alpha beta hydrolase
GII76_17985	COG2208	phosphoserine phosphatase activity
GII76_17990	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII76_17995	COG1874	Beta-galactosidase
GII76_18000	COG3833	ABC-type maltose transport systems, permease component
GII76_18005	COG1175	transmembrane transport
GII76_18010	COG2182	Extracellular solute-binding protein
GII76_18015	COG1609	Transcriptional regulator
GII76_18020	COG2186	Transcriptional regulator
GII76_18025	COG1620	l-lactate permease
GII76_18030	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII76_18040	COG5039	Polysaccharide pyruvyl transferase
GII76_18045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII76_18050	COG0110	maltose O-acetyltransferase activity
GII76_18055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII76_18060	COG2244	polysaccharide biosynthetic process
GII76_18065	COG1216	Glycosyl transferase, family 2
GII76_18070	COG5039	Polysaccharide pyruvyl transferase
GII76_18075	COG1216	Glycosyl transferase, family 2
GII76_18085	COG0438	transferase activity, transferring glycosyl groups
GII76_18090	COG1215	transferase activity, transferring glycosyl groups
GII76_18095	COG0438	transferase activity, transferring glycosyl groups
GII76_18100	COG1086	Polysaccharide biosynthesis protein
GII76_18105	COG0489	protein tyrosine kinase activity
GII76_18110	COG3944	biosynthesis protein
GII76_18115	COG1396	sequence-specific DNA binding
GII76_18120	COG2272	Belongs to the type-B carboxylesterase lipase family
GII76_18130	COG3479	Phenolic acid decarboxylase
GII76_18140	COG1794	racemase activity, acting on amino acids and derivatives
GII76_18145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII76_18150	COG1621	beta-fructofuranosidase activity
GII76_18155	COG1621	beta-fructofuranosidase activity
GII76_18160	COG0531	amino acid
GII76_18165	COG1309	transcriptional regulator
GII76_18170	COG2076	Multidrug Resistance protein
GII76_18175	COG2076	Multidrug Resistance protein
GII76_18185	COG0277	FAD linked oxidase domain protein
GII76_18190	COG3621	Patatin-like phospholipase
GII76_18200	COG0740	serine-type endopeptidase activity
GII76_18205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII76_18210	COG0366	Alpha amylase catalytic
GII76_18215	COG1554	hydrolase, family 65, central catalytic
GII76_18220	COG5521	maltodextrose utilization protein MalA
GII76_18225	COG3833	ABC-type maltose transport systems, permease component
GII76_18230	COG1175	transmembrane transport
GII76_18235	COG2182	Extracellular solute-binding protein
GII76_18240	COG0366	Alpha amylase catalytic
GII76_18245	COG1609	Transcriptional regulator
GII76_18250	COG1611	Belongs to the LOG family
GII76_18255	COG1694	Mazg nucleotide pyrophosphohydrolase
GII76_18260	COG0659	secondary active sulfate transmembrane transporter activity
GII76_18265	COG0288	reversible hydration of carbon dioxide
GII76_18270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII76_18275	COG0577	efflux transmembrane transporter activity
GII76_18280	COG1136	(ABC) transporter
GII76_18285	COG5002	protein histidine kinase activity
GII76_18290	COG0745	RESPONSE REGULATOR receiver
GII76_18300	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII76_18305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII76_18310	COG1481	regulation of sporulation
GII76_18315	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII76_18320	COG1660	Displays ATPase and GTPase activities
GII76_18325	COG1051	belongs to the nudix hydrolase family
GII76_18330	COG0492	ferredoxin-NADP+ reductase activity
GII76_18335	COG0791	NLP P60 protein
GII76_18335	COG3883	PFAM NLP P60 protein
GII76_18340	COG0457	Tetratricopeptide repeat
GII76_18345	COG1132	(ABC) transporter
GII76_18365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII76_18365	COG0140	phosphoribosyl-ATP diphosphatase activity
GII76_18370	COG0107	imidazoleglycerol-phosphate synthase activity
GII76_18375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII76_18380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII76_18385	COG0131	Imidazoleglycerol-phosphate dehydratase
GII76_18390	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII76_18395	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII76_18400	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII76_18405	COG4990	cell redox homeostasis
GII76_18410	COG5297	Belongs to the glycosyl hydrolase family 6
GII76_18415	COG0110	maltose O-acetyltransferase activity
GII76_18420	COG0546	phosphoglycolate phosphatase activity
GII76_18425	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII76_18430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII76_18435	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII76_18440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII76_18445	COG0363	glucosamine-6-phosphate deaminase activity
GII76_18455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII76_18460	COG1846	Transcriptional regulator
GII76_18465	COG2124	cytochrome p450
GII76_18475	COG1846	Transcriptional regulator
GII76_18480	COG2814	Major facilitator Superfamily
GII76_18485	COG1950	PFAM Membrane protein of
GII76_18490	COG1983	PspC domain protein
GII76_18495	COG3595	metallopeptidase activity
GII76_18510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII76_18515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII76_18520	COG0556	nucleotide-excision repair
GII76_18525	COG4897	Protein conserved in bacteria
GII76_18530	COG0574	Belongs to the PEP-utilizing enzyme family
GII76_18530	COG3848	Pyruvate phosphate dikinase
GII76_18535	COG1309	transcriptional regulator
GII76_18540	COG2814	Major facilitator Superfamily
GII76_18545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII76_18555	COG3409	Peptidoglycan-binding domain 1 protein
GII76_18555	COG0793	Belongs to the peptidase S41A family
GII76_18560	COG2177	Part of the ABC transporter FtsEX involved in
GII76_18565	COG2884	Cell division ATP-binding protein ftsE
GII76_18570	COG2010	Cytochrome c
GII76_18575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII76_18585	COG0653	protein targeting
GII76_18590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII76_18605	COG1516	flagellar protein fliS
GII76_18610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII76_18615	COG1334	flagellar protein FlaG
GII76_18620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII76_18625	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII76_18630	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII76_18640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII76_18645	COG1256	bacterial-type flagellum assembly
GII76_18645	COG4786	Flagellar basal body rod
GII76_18650	COG3418	PFAM FlgN family protein
GII76_18655	COG2747	anti-sigma28 factor FlgM
GII76_18665	COG1040	competence protein
GII76_18675	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII76_18680	COG1307	EDD domain protein, DegV family
GII76_18685	COG2197	response regulator
GII76_18690	COG4585	Histidine kinase
GII76_18695	COG1739	Uncharacterized protein family UPF0029
GII76_18700	COG1316	TRANSCRIPTIONal
GII76_18705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII76_18710	COG0438	transferase activity, transferring glycosyl groups
GII76_18715	COG1215	transferase activity, transferring glycosyl groups
GII76_18720	COG3206	protein involved in exopolysaccharide biosynthesis
GII76_18725	COG3307	-O-antigen
GII76_18730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII76_18735	COG0297	glycogen (starch) synthase activity
GII76_18735	COG0438	transferase activity, transferring glycosyl groups
GII76_18740	COG2244	polysaccharide biosynthetic process
GII76_18755	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII76_18755	COG2247	cell wall binding repeat
GII76_18760	COG2385	sporulation resulting in formation of a cellular spore
GII76_18760	COG2247	cell wall binding repeat
GII76_18770	COG1316	TRANSCRIPTIONal
GII76_18775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII76_18795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII76_18800	COG1134	teichoic acid transport
GII76_18805	COG1682	transport, permease protein
GII76_18820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII76_18820	COG1215	transferase activity, transferring glycosyl groups
GII76_18825	COG0463	Glycosyl transferase, family 2
GII76_18870	COG4193	domain, Protein
GII76_18875	COG1482	cell wall glycoprotein biosynthetic process
GII76_18880	COG0697	spore germination
GII76_18885	COG0814	amino acid
GII76_18895	COG2814	Major facilitator Superfamily
GII76_18900	COG1316	TRANSCRIPTIONal
GII76_18905	COG0561	phosphatase activity
GII76_18910	COG0791	NLP P60 protein
GII76_18920	COG2843	Capsule synthesis protein
GII76_18930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII76_18935	COG1609	Transcriptional regulator
GII76_18940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII76_18945	COG1869	D-ribose catabolic process
GII76_18950	COG1129	ABC transporter
GII76_18955	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII76_18960	COG1879	ABC-type sugar transport system periplasmic component
GII76_18965	COG3103	Sh3 type 3 domain protein
GII76_18975	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII76_18980	COG3527	Alpha-acetolactate decarboxylase
GII76_18985	COG0028	Belongs to the TPP enzyme family
GII76_18990	COG0583	DNA-binding transcription factor activity
GII76_18995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII76_19010	COG5337	Spore coat protein CotH
GII76_19020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII76_19030	COG0405	Gamma-glutamyltransferase
GII76_19035	COG1522	sequence-specific DNA binding
GII76_19040	COG2059	Chromate
GII76_19045	COG2059	Chromate
GII76_19055	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII76_19060	COG0583	DNA-binding transcription factor activity
GII76_19090	COG5444	nuclease activity
GII76_19110	COG3878	Protein conserved in bacteria
GII76_19115	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII76_19120	COG4464	protein tyrosine phosphatase activity
GII76_19125	COG0489	protein tyrosine kinase activity
GII76_19130	COG3944	biosynthesis protein
GII76_19140	COG4715	Zinc finger, swim domain protein
GII76_19145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII76_19150	COG0561	phosphatase activity
GII76_19155	COG1349	DNA-binding transcription factor activity
GII76_19160	COG0629	single-stranded DNA binding
GII76_19175	COG3764	Sortase (surface protein transpeptidase)
GII76_19190	COG1970	mechanosensitive ion channel activity
GII76_19195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII76_19200	COG0457	Tetratricopeptide repeat
GII76_19205	COG4786	Flagellar basal body rod
GII76_19210	COG4786	Flagellar basal body rod
GII76_19215	COG1077	Cell shape determining protein MreB Mrl
GII76_19220	COG1609	Transcriptional regulator
GII76_19230	COG1846	Transcriptional regulator
GII76_19235	COG2814	Major facilitator Superfamily
GII76_19240	COG3420	alginic acid biosynthetic process
GII76_19245	COG1953	Uracil, thiamine, allantoin
GII76_19250	COG0477	Major facilitator Superfamily
GII76_19255	COG1335	isochorismatase
GII76_19265	COG0004	ammonium transporteR
GII76_19270	COG0347	Belongs to the P(II) protein family
GII76_19275	COG0671	phosphoesterase, PA-phosphatase related
GII76_19285	COG0739	heme binding
GII76_19290	COG1247	-acetyltransferase
GII76_19310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII76_19315	COG0789	Transcriptional regulator
GII76_19325	COG2910	NAD(P)H-binding
GII76_19330	COG1959	2 iron, 2 sulfur cluster binding
GII76_19335	COG0804	urea catabolic process
GII76_19340	COG0832	Belongs to the urease beta subunit family
GII76_19345	COG0831	urea catabolic process
GII76_19360	COG3237	CsbD-like
GII76_19365	COG1994	Peptidase M50
GII76_19370	COG0457	Tetratricopeptide repeat
GII76_19375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII76_19380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII76_19390	COG2304	oxidoreductase activity
GII76_19400	COG2304	oxidoreductase activity
GII76_19405	COG2385	sporulation resulting in formation of a cellular spore
GII76_19410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII76_19420	COG4836	Membrane
GII76_19430	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII76_19435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII76_19440	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII76_19445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII76_19450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII76_19455	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII76_19460	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII76_19465	COG0356	it plays a direct role in the translocation of protons across the membrane
GII76_19475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII76_19480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII76_19485	COG4475	Protein of unknown function (DUF436)
GII76_19490	COG0698	ribose 5-phosphate isomerase
GII76_19495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII76_19500	COG1971	Probably functions as a manganese efflux pump
GII76_19505	COG0009	L-threonylcarbamoyladenylate synthase
GII76_19510	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII76_19530	COG2890	protein-(glutamine-N5) methyltransferase activity
GII76_19535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII76_19540	COG0346	lactoylglutathione lyase activity
GII76_19545	COG0789	Transcriptional regulator
GII76_19550	COG0679	Auxin Efflux Carrier
GII76_19555	COG0281	malic enzyme
GII76_19560	COG1435	thymidine kinase activity
GII76_19565	COG0254	rRNA binding
GII76_19570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII76_19580	COG1494	fructose-1,6-bisphosphatase
GII76_19585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII76_19590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII76_19595	COG0191	fructose-bisphosphate aldolase activity
GII76_19600	COG2204	response regulator
GII76_19605	COG4821	SIS domain
GII76_19610	COG0504	CTP synthase activity
GII76_19615	COG3343	RNA polymerase activity
GII76_19620	COG1960	acyl-CoA dehydrogenase activity
GII76_19625	COG2181	nitrate reductase activity
GII76_19625	COG0247	lactate metabolic process
GII76_19630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII76_19635	COG4294	response to UV
GII76_19645	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII76_19650	COG1132	(ABC) transporter
GII76_19655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII76_19665	COG2181	nitrate reductase activity
GII76_19670	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GII76_19675	COG1140	nitrate reductase beta subunit
GII76_19680	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII76_19685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII76_19695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII76_19700	COG2223	nitrite transmembrane transporter activity
GII76_19705	COG0018	arginyl-trna synthetase
GII76_19710	COG4506	Protein conserved in bacteria
GII76_19725	COG0535	radical SAM domain protein
GII76_19735	COG1131	(ABC) transporter
GII76_19740	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII76_19745	COG0612	Peptidase, M16
GII76_19750	COG0612	Peptidase, M16
GII76_19760	COG3391	amine dehydrogenase activity
GII76_19765	COG3391	amine dehydrogenase activity
GII76_19775	COG0457	Tetratricopeptide repeat
GII76_19805	COG1131	(ABC) transporter
GII76_19815	COG0010	Belongs to the arginase family
GII76_19820	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII76_19825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII76_19835	COG1994	Peptidase M50
GII76_19840	COG1942	4-Oxalocrotonate Tautomerase
GII76_19845	COG1846	Transcriptional regulator
GII76_19850	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII76_19855	COG0477	Major facilitator Superfamily
GII76_19860	COG1959	2 iron, 2 sulfur cluster binding
GII76_19865	COG3465	dGTPase activity
GII76_19870	COG1078	dGTPase activity
GII76_19875	COG4844	belongs to the
GII76_19885	COG0697	spore germination
GII76_19890	COG0095	Lipoate-protein ligase
GII76_19895	COG0583	DNA-binding transcription factor activity
GII76_19900	COG0280	phosphate acetyltransferase
GII76_19910	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_19915	COG0436	Aminotransferase
GII76_19920	COG2814	Major facilitator Superfamily
GII76_19925	COG0151	Belongs to the GarS family
GII76_19930	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_19935	COG1917	Cupin 2, conserved barrel domain protein
GII76_19940	COG0077	Prephenate dehydratase
GII76_19945	COG2814	Major facilitator Superfamily
GII76_19950	COG0833	amino acid
GII76_19955	COG4187	Peptidase family M20/M25/M40
GII76_19960	COG1012	belongs to the aldehyde dehydrogenase family
GII76_19965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII76_19975	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII76_19980	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII76_19985	COG1088	dTDP-glucose 4,6-dehydratase activity
GII76_19990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII76_19995	COG3980	spore coat polysaccharide biosynthesis protein
GII76_20000	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII76_20005	COG2089	acid synthase
GII76_20010	COG0456	acetyltransferase
GII76_20015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII76_20020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII76_20025	COG0463	Glycosyl transferase, family 2
GII76_20035	COG2363	Small membrane protein
GII76_20040	COG2233	PERMEase
GII76_20050	COG1012	belongs to the aldehyde dehydrogenase family
GII76_20055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII76_20060	COG1216	Glycosyl transferase, family 2
GII76_20065	COG0351	phosphomethylpyrimidine kinase
GII76_20075	COG1621	beta-fructofuranosidase activity
GII76_20080	COG1263	PTS System
GII76_20080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_20085	COG2116	formate transmembrane transporter activity
GII76_20090	COG3711	transcriptional antiterminator
GII76_20100	COG1404	Belongs to the peptidase S8 family
GII76_20105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII76_20110	COG0778	Nitroreductase
GII76_20115	COG0772	Belongs to the SEDS family
GII76_20125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII76_20130	COG1845	cytochrome c oxidase, subunit III
GII76_20135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII76_20140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII76_20145	COG2261	transglycosylase associated protein
GII76_20150	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII76_20155	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII76_20160	COG2246	polysaccharide biosynthetic process
GII76_20165	COG1309	transcriptional regulator
GII76_20175	COG3162	membrane
GII76_20180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII76_20185	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII76_20190	COG2837	iron assimilation
GII76_20195	COG2822	iron ion transport
GII76_20200	COG0672	)-iron permease
GII76_20205	COG0352	thiamine-phosphate diphosphorylase activity
GII76_20210	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII76_20215	COG0583	DNA-binding transcription factor activity
GII76_20220	COG1380	Effector of murein hydrolase LrgA
GII76_20225	COG1346	cytolysis
GII76_20230	COG2814	Major facilitator Superfamily
GII76_20235	COG4895	conserved protein (DUF2196)
GII76_20240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII76_20245	COG0346	lactoylglutathione lyase activity
GII76_20250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII76_20255	COG1404	Belongs to the peptidase S8 family
GII76_20260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_20260	COG1263	PTS System
GII76_20265	COG3711	transcriptional antiterminator
GII76_20270	COG1442	glycosyl transferase family 8
GII76_20275	COG5522	Integral membrane protein (intg_mem_TP0381)
GII76_20280	COG1846	Transcriptional regulator
GII76_20285	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII76_20290	COG2234	aminopeptidase activity
GII76_20310	COG2357	RelA SpoT domain protein
GII76_20315	COG1575	Belongs to the MenA family. Type 1 subfamily
GII76_20330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII76_20335	COG1696	Membrane protein involved in D-alanine export
GII76_20340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII76_20345	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII76_20350	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII76_20355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII76_20360	COG1486	melibiose metabolic process
GII76_20365	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII76_20370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII76_20375	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII76_20380	COG3711	transcriptional antiterminator
GII76_20380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII76_20390	COG2094	Belongs to the DNA glycosylase MPG family
GII76_20395	COG0753	catalase activity
GII76_20405	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII76_20410	COG1131	(ABC) transporter
GII76_20430	COG1595	DNA-templated transcription, initiation
GII76_20435	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII76_20440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII76_20445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII76_20450	COG4988	ABC transporter
GII76_20455	COG1294	oxidase, subunit
GII76_20460	COG1271	oxidase subunit
GII76_20465	COG3493	citrate carrier protein
GII76_20470	COG0501	Belongs to the peptidase M48B family
GII76_20480	COG0726	polysaccharide deacetylase
GII76_20485	COG3842	ATPase activity
GII76_20490	COG2508	Transcriptional regulator
GII76_20495	COG1012	belongs to the aldehyde dehydrogenase family
GII76_20500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII76_20510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII76_20515	COG1881	PFAM PEBP family protein
GII76_20520	COG0583	DNA-binding transcription factor activity
GII76_20530	COG4585	Histidine kinase
GII76_20535	COG2197	response regulator
GII76_20540	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII76_20550	COG4894	glucomannan catabolic process
GII76_20555	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII76_20560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII76_20565	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_20570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII76_20575	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII76_20580	COG2610	gluconate transmembrane transporter activity
GII76_20585	COG0500	methyltransferase
GII76_20590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII76_20605	COG0693	protein deglycase activity
GII76_20605	COG0753	catalase activity
GII76_20610	COG2851	Citrate transporter
GII76_20615	COG2273	Hydrolase Family 16
GII76_20620	COG3711	transcriptional antiterminator
GII76_20630	COG2270	Major facilitator Superfamily
GII76_20635	COG0513	Belongs to the DEAD box helicase family
GII76_20640	COG3401	FG-GAP repeat protein
GII76_20640	COG2755	lipolytic protein G-D-S-L family
GII76_20665	COG0697	spore germination
GII76_20670	COG0589	response to stress
GII76_20675	COG2723	6-phospho-beta-galactosidase activity
GII76_20680	COG1263	PTS System
GII76_20680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_20680	COG2190	(PTS) system
GII76_20695	COG5444	nuclease activity
GII76_20710	COG3507	Belongs to the glycosyl hydrolase 43 family
GII76_20725	COG2986	histidine ammonia-lyase
GII76_20730	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII76_20735	COG1228	amidohydrolase
GII76_20740	COG0010	Belongs to the arginase family
GII76_20745	COG0833	amino acid
GII76_20750	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII76_20755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII76_20760	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII76_20765	COG2390	Transcriptional regulator
GII76_20775	COG3192	ethanolamine utilization protein
GII76_20780	COG2079	MmgE PrpD family protein
GII76_20790	COG1126	abc transporter atp-binding protein
GII76_20795	COG0765	amino acid transport
GII76_20800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII76_20820	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII76_20825	COG0561	phosphatase activity
GII76_20855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII76_20860	COG5294	Protein conserved in bacteria
GII76_20865	COG0577	efflux transmembrane transporter activity
GII76_20870	COG1136	(ABC) transporter
GII76_20875	COG2205	protein histidine kinase activity
GII76_20880	COG0745	RESPONSE REGULATOR receiver
GII76_20885	COG0191	fructose-bisphosphate aldolase activity
GII76_20890	COG1082	Xylose isomerase domain protein TIM barrel
GII76_20895	COG1082	Xylose isomerase domain protein TIM barrel
GII76_20900	COG0673	inositol 2-dehydrogenase activity
GII76_20905	COG2814	Major facilitator Superfamily
GII76_20910	COG1082	Xylose isomerase domain protein TIM barrel
GII76_20915	COG3962	Belongs to the TPP enzyme family
GII76_20920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII76_20925	COG3718	enzyme involved in inositol metabolism
GII76_20930	COG1012	belongs to the aldehyde dehydrogenase family
GII76_20935	COG1349	DNA-binding transcription factor activity
GII76_20940	COG0667	Aldo Keto reductase
GII76_20955	COG2814	Major facilitator Superfamily
GII76_20960	COG0326	Molecular chaperone. Has ATPase activity
GII76_20970	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_20975	COG1309	transcriptional regulator
GII76_20980	COG1012	belongs to the aldehyde dehydrogenase family
GII76_20985	COG1714	RDD family
GII76_20990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GII76_21000	COG1714	RDD family
GII76_21005	COG2311	Membrane
GII76_21010	COG1917	Cupin 2, conserved barrel domain protein
GII76_21015	COG1309	transcriptional regulator
GII76_21020	COG1028	Short-chain dehydrogenase reductase Sdr
GII76_21025	COG1846	Transcriptional regulator
GII76_21030	COG1380	Effector of murein hydrolase LrgA
GII76_21035	COG1346	cytolysis
GII76_21040	COG5039	Polysaccharide pyruvyl transferase
GII76_21045	COG1929	Belongs to the glycerate kinase type-1 family
GII76_21050	COG1802	Transcriptional regulator
GII76_21055	COG1070	Carbohydrate kinase
GII76_21060	COG2610	gluconate transmembrane transporter activity
GII76_21065	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII76_21070	COG0450	alkyl hydroperoxide reductase
GII76_21075	COG3634	alkyl hydroperoxide reductase activity
GII76_21085	COG2723	6-phospho-beta-galactosidase activity
GII76_21090	COG2190	(PTS) system
GII76_21095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII76_21095	COG1263	PTS System
GII76_21095	COG2190	(PTS) system
GII76_21100	COG2188	Transcriptional regulator
GII76_21110	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII76_21120	COG1204	response to ionizing radiation
GII76_21130	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII76_21145	COG1063	alcohol dehydrogenase
GII76_21165	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII76_21170	COG0456	acetyltransferase
GII76_21175	COG0457	Tetratricopeptide repeat
GII76_21185	COG0010	Belongs to the arginase family
GII76_21190	COG0833	amino acid
GII76_21195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII76_21200	COG3829	transcription factor binding
GII76_21205	COG5002	protein histidine kinase activity
GII76_21230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII76_21235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII76_21240	COG4853	Protein conserved in bacteria
GII76_21245	COG4863	YycH protein
GII76_21250	COG5002	protein histidine kinase activity
GII76_21255	COG0745	RESPONSE REGULATOR receiver
GII76_21285	COG0346	lactoylglutathione lyase activity
GII76_21290	COG0305	Participates in initiation and elongation during chromosome replication
GII76_21305	COG3093	addiction module antidote protein HigA
GII76_21310	COG2807	transmembrane transport
GII76_21315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII76_21320	COG0359	binds to the 23S rRNA
GII76_21325	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII76_21330	COG4241	membrane
GII76_21340	COG5577	PFAM Coat F domain
GII76_21345	COG1733	regulation of RNA biosynthetic process
GII76_21350	COG1227	inorganic diphosphatase activity
GII76_21360	COG2271	Major facilitator Superfamily
GII76_21365	COG0789	Transcriptional regulator
GII76_21365	COG4978	Transcriptional regulator
GII76_21375	COG4319	ketosteroid isomerase
GII76_21380	COG1357	PFAM Pentapeptide repeats (8 copies)
GII76_21385	COG2814	Major facilitator Superfamily
GII76_21390	COG0583	DNA-binding transcription factor activity
GII76_21395	COG2153	protein acetylation
GII76_21405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII76_21410	COG1846	Transcriptional regulator
GII76_21415	COG2153	protein acetylation
GII76_21420	COG2364	Membrane
GII76_21425	COG0456	acetyltransferase
GII76_21430	COG2315	Protein conserved in bacteria
GII76_21435	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII76_21445	COG2814	Major facilitator Superfamily
GII76_21455	COG1331	Highly conserved protein containing a thioredoxin domain
GII76_21470	COG0789	Transcriptional regulator
GII76_21475	COG0697	spore germination
GII76_21485	COG1280	lysine exporter protein (LysE YggA)
GII76_21490	COG1331	Highly conserved protein containing a thioredoxin domain
GII76_21495	COG1331	Highly conserved protein containing a thioredoxin domain
GII76_21500	COG1266	CAAX protease self-immunity
GII76_21505	COG0477	Major facilitator Superfamily
GII76_21505	COG2814	Major facilitator Superfamily
GII76_21510	COG0110	maltose O-acetyltransferase activity
GII76_21515	COG0346	lactoylglutathione lyase activity
GII76_21520	COG1609	Transcriptional regulator
GII76_21525	COG0708	Exodeoxyribonuclease III
GII76_21530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII76_21535	COG0629	single-stranded DNA binding
GII76_21540	COG0360	Binds together with S18 to 16S ribosomal RNA
GII76_21545	COG0012	GTP binding
GII76_21550	COG0243	molybdopterin cofactor binding
GII76_21555	COG4481	Protein conserved in bacteria
GII76_21560	COG3949	Membrane
GII76_21570	COG1475	DNA binding
GII76_21575	COG1192	Involved in chromosome partitioning
GII76_21585	COG1475	DNA binding
GII76_21590	COG0357	Ribosomal RNA small subunit methyltransferase G
GII76_21595	COG0445	tRNA wobble uridine modification
GII76_21600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII76_21605	COG1847	R3H domain protein
GII76_21610	COG0706	membrane insertase activity
GII76_21615	COG0594	ribonuclease P activity
GII76_21620	COG0230	Belongs to the bacterial ribosomal protein bL34 family