locus-tag	class	description
MM522_00005	COG0246	Mannitol dehydrogenase
MM522_00010	COG0473	3-isopropylmalate dehydrogenase activity
MM522_00015	COG0681	Belongs to the peptidase S26 family
MM522_00020	COG0412	Dienelactone hydrolase
MM522_00025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MM522_00035	COG0561	phosphatase activity
MM522_00040	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MM522_00045	COG1914	H( )-stimulated, divalent metal cation uptake system
MM522_00050	COG4336	lyase activity
MM522_00055	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MM522_00060	COG1984	allophanate hydrolase subunit 2
MM522_00065	COG1414	Transcriptional regulator
MM522_00070	COG2755	lipolytic protein G-D-S-L family
MM522_00080	COG2329	Antibiotic biosynthesis monooxygenase
MM522_00085	COG0768	penicillin binding
MM522_00090	COG4989	oxidoreductase activity
MM522_00095	COG3711	transcriptional antiterminator
MM522_00100	COG0318	PFAM AMP-dependent synthetase and ligase
MM522_00105	COG2226	methyltransferase
MM522_00110	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_00115	COG1917	Cupin 2, conserved barrel domain protein
MM522_00120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM522_00125	COG3871	stress protein (general stress protein 26)
MM522_00135	COG2814	Major facilitator Superfamily
MM522_00140	COG1522	sequence-specific DNA binding
MM522_00145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MM522_00145	COG0551	DNA topoisomerase type I activity
MM522_00150	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MM522_00155	COG3706	GGDEF domain
MM522_00160	COG5298	Protein conserved in bacteria
MM522_00165	COG1215	transferase activity, transferring glycosyl groups
MM522_00175	COG0531	amino acid
MM522_00180	COG0494	nUDIX hydrolase
MM522_00185	COG0028	Belongs to the TPP enzyme family
MM522_00205	COG2261	transglycosylase associated protein
MM522_00210	COG4876	unkown
MM522_00215	COG2217	Heavy metal translocating P-type atpase
MM522_00230	COG2329	Antibiotic biosynthesis monooxygenase
MM522_00235	COG3546	catalase activity
MM522_00240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MM522_00245	COG3290	protein histidine kinase activity
MM522_00250	COG4565	transcriptional regulatory protein
MM522_00255	COG1301	dicarboxylic acid transport
MM522_00260	COG0628	permease
MM522_00265	COG1131	(ABC) transporter
MM522_00270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MM522_00280	COG1960	acyl-CoA dehydrogenase activity
MM522_00295	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MM522_00300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM522_00305	COG1181	Belongs to the D-alanine--D-alanine ligase family
MM522_00310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MM522_00315	COG0513	Belongs to the DEAD box helicase family
MM522_00320	COG3402	PFAM membrane-flanked domain
MM522_00325	COG3428	Bacterial PH domain
MM522_00330	COG0705	Rhomboid family
MM522_00335	COG0736	holo-[acyl-carrier-protein] synthase activity
MM522_00340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MM522_00345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MM522_00350	COG0864	Transcriptional regulator
MM522_00355	COG2337	Toxic component of a toxin-antitoxin (TA) module
MM522_00360	COG1366	Belongs to the anti-sigma-factor antagonist family
MM522_00365	COG1366	Belongs to the anti-sigma-factor antagonist family
MM522_00370	COG2172	sigma factor antagonist activity
MM522_00375	COG2208	phosphoserine phosphatase activity
MM522_00380	COG1366	Belongs to the anti-sigma-factor antagonist family
MM522_00385	COG2172	sigma factor antagonist activity
MM522_00390	COG1191	sigma factor activity
MM522_00395	COG2208	phosphoserine phosphatase activity
MM522_00400	COG2183	response to ionizing radiation
MM522_00410	COG3091	SprT-like family
MM522_00465	COG0515	serine threonine protein kinase
MM522_00485	COG0515	serine threonine protein kinase
MM522_00490	COG1132	(ABC) transporter
MM522_00505	COG1476	TRANSCRIPTIONal
MM522_00515	COG3239	Fatty acid desaturase
MM522_00520	COG1278	Cold shock
MM522_00525	COG1329	Transcriptional regulator
MM522_00530	COG0697	spore germination
MM522_00535	COG1917	Cupin 2, conserved barrel domain protein
MM522_00535	COG2207	Transcriptional regulator
MM522_00540	COG0697	spore germination
MM522_00545	COG2207	Transcriptional regulator
MM522_00545	COG3708	Transcriptional regulator
MM522_00550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM522_00555	COG0477	Major facilitator Superfamily
MM522_00565	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
MM522_00575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM522_00580	COG1309	transcriptional regulator
MM522_00585	COG0697	spore germination
MM522_00590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM522_00595	COG2030	dehydratase
MM522_00600	COG3545	Serine hydrolase
MM522_00605	COG1733	regulation of RNA biosynthetic process
MM522_00610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM522_00615	COG1733	regulation of RNA biosynthetic process
MM522_00620	COG2249	NAD(P)H dehydrogenase (quinone) activity
MM522_00625	COG2814	Major facilitator Superfamily
MM522_00630	COG1309	transcriptional regulator
MM522_00635	COG0640	Transcriptional regulator
MM522_00640	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MM522_00650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM522_00655	COG0697	spore germination
MM522_00660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM522_00665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MM522_00670	COG0640	Transcriptional regulator
MM522_00675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MM522_00690	COG4585	Histidine kinase
MM522_00695	COG2197	response regulator
MM522_00700	COG2409	Drug exporters of the RND superfamily
MM522_00705	COG0596	Alpha beta hydrolase
MM522_00710	COG1811	Na channel or pump
MM522_00715	COG4978	Transcriptional regulator
MM522_00715	COG0789	Transcriptional regulator
MM522_00725	COG0778	Nitroreductase
MM522_00730	COG0346	lactoylglutathione lyase activity
MM522_00735	COG2259	Doxx family
MM522_00740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM522_00760	COG2323	membrane
MM522_00765	COG2323	membrane
MM522_00770	COG0071	Belongs to the small heat shock protein (HSP20) family
MM522_00785	COG1309	transcriptional regulator
MM522_00795	COG0456	acetyltransferase
MM522_00800	COG0488	(ABC) transporter
MM522_00805	COG1113	amino acid transport
MM522_00810	COG2318	DinB family
MM522_00815	COG1846	Transcriptional regulator
MM522_00820	COG1033	growth of symbiont in host cell
MM522_00820	COG2409	Drug exporters of the RND superfamily
MM522_00825	COG0778	Nitroreductase
MM522_00830	COG1846	Transcriptional regulator
MM522_00835	COG2814	Major facilitator Superfamily
MM522_00840	COG0730	response to heat
MM522_00845	COG1802	Transcriptional regulator
MM522_00850	COG1388	LysM domain
MM522_00850	COG3858	chitin binding
MM522_00855	COG1819	glycosyl
MM522_00865	COG1785	Belongs to the alkaline phosphatase family
MM522_00870	COG5646	InterPro IPR014922
MM522_00880	COG0454	-acetyltransferase
MM522_00885	COG1078	dGTPase activity
MM522_00890	COG1388	LysM domain
MM522_00895	COG2814	Major facilitator Superfamily
MM522_00900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MM522_00905	COG1447	Phosphotransferase system cellobiose-specific component IIA
MM522_00910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MM522_00915	COG2723	6-phospho-beta-galactosidase activity
MM522_00920	COG2188	Transcriptional regulator
MM522_00925	COG1940	carbohydrate kinase activity
MM522_00930	COG1482	cell wall glycoprotein biosynthetic process
MM522_00935	COG4124	Belongs to the glycosyl hydrolase 26 family
MM522_00980	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MM522_00985	COG0802	atpase or kinase
MM522_00990	COG1214	PFAM Peptidase M22, glycoprotease
MM522_00995	COG0456	acetyltransferase
MM522_01000	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MM522_01005	COG0488	(ABC) transporter
MM522_01010	COG0315	cyclic pyranopterin monophosphate synthase activity
MM522_01015	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MM522_01020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MM522_01025	COG0805	protein transport
MM522_01035	COG1266	CAAX protease self-immunity
MM522_01045	COG0459	protein refolding
MM522_01055	COG1073	alpha beta
MM522_01060	COG0457	Tetratricopeptide repeat
MM522_01065	COG1063	alcohol dehydrogenase
MM522_01070	COG2211	Major facilitator Superfamily
MM522_01075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM522_01080	COG1842	Phage shock protein A
MM522_01085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MM522_01090	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MM522_01095	COG4260	virion core protein, lumpy skin disease virus
MM522_01105	COG2814	Major facilitator Superfamily
MM522_01110	COG1063	alcohol dehydrogenase
MM522_01115	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MM522_01120	COG0823	Involved in the tonB-independent uptake of proteins
MM522_01135	COG2267	carboxylic ester hydrolase activity
MM522_01145	COG2132	Multicopper oxidase
MM522_01150	COG1113	amino acid transport
MM522_01160	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MM522_01165	COG0714	Associated with various cellular activities
MM522_01170	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MM522_01175	COG1305	Transglutaminase-like
MM522_01180	COG0519	Catalyzes the synthesis of GMP from XMP
MM522_01180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MM522_01195	COG2252	PERMEase
MM522_01200	COG3064	Membrane
MM522_01210	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MM522_01220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MM522_01225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MM522_01230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MM522_01235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MM522_01240	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MM522_01245	COG0047	phosphoribosylformylglycinamidine synthase activity
MM522_01250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MM522_01255	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MM522_01260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MM522_01265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MM522_01270	COG0138	bifunctional purine biosynthesis protein purh
MM522_01275	COG0151	Belongs to the GarS family
MM522_01280	COG1522	sequence-specific DNA binding
MM522_01285	COG0531	amino acid
MM522_01295	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MM522_01300	COG1470	cell adhesion involved in biofilm formation
MM522_01305	COG4496	protein, YerC YecD
MM522_01310	COG0069	glutamate synthase activity
MM522_01315	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MM522_01320	COG0210	DNA helicase
MM522_01325	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MM522_01330	COG4851	CamS sex pheromone cAM373 precursor
MM522_01335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MM522_01340	COG1285	pathogenesis
MM522_01345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MM522_01350	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MM522_01355	COG0154	amidase activity
MM522_01360	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MM522_01370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MM522_01375	COG1597	lipid kinase activity
MM522_01380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MM522_01385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MM522_01405	COG0457	Tetratricopeptide repeat
MM522_01420	COG5444	nuclease activity
MM522_01425	COG3391	amine dehydrogenase activity
MM522_01435	COG0457	Tetratricopeptide repeat
MM522_01445	COG0217	transcriptional regulatory protein
MM522_01455	COG1309	transcriptional regulator
MM522_01460	COG3631	Ketosteroid isomerase-related protein
MM522_01480	COG3546	catalase activity
MM522_01485	COG0454	-acetyltransferase
MM522_01495	COG5578	integral membrane protein
MM522_01500	COG2972	Histidine kinase
MM522_01505	COG2207	Transcriptional regulator
MM522_01505	COG4753	response regulator
MM522_01510	COG1653	transport
MM522_01515	COG1175	transmembrane transport
MM522_01520	COG0395	ABC-type sugar transport system, permease component
MM522_01525	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MM522_01530	COG2207	Transcriptional regulator
MM522_01535	COG2755	lipolytic protein G-D-S-L family
MM522_01545	COG5578	integral membrane protein
MM522_01550	COG3401	FG-GAP repeat protein
MM522_01555	COG3401	FG-GAP repeat protein
MM522_01560	COG2755	lipolytic protein G-D-S-L family
MM522_01565	COG1874	Beta-galactosidase
MM522_01575	COG1653	transport
MM522_01580	COG4209	transmembrane transport
MM522_01585	COG0395	ABC-type sugar transport system, permease component
MM522_01590	COG1486	melibiose metabolic process
MM522_01595	COG2323	membrane
MM522_01600	COG2329	Antibiotic biosynthesis monooxygenase
MM522_01605	COG0346	lactoylglutathione lyase activity
MM522_01620	COG5583	Uncharacterized small protein (DUF2292)
MM522_01625	COG0670	Belongs to the BI1 family
MM522_01660	COG2124	cytochrome p450
MM522_01660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MM522_01665	COG1368	sulfuric ester hydrolase activity
MM522_01670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MM522_01675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MM522_01680	COG1442	glycosyl transferase family 8
MM522_01685	COG1216	Glycosyl transferase, family 2
MM522_01690	COG1442	glycosyl transferase family 8
MM522_01695	COG2223	nitrite transmembrane transporter activity
MM522_01700	COG1011	Hydrolase
MM522_01705	COG0531	amino acid
MM522_01710	COG1012	belongs to the aldehyde dehydrogenase family
MM522_01715	COG0840	transmembrane signaling receptor activity
MM522_01720	COG0488	(ABC) transporter
MM522_01730	COG0789	Transcriptional regulator
MM522_01735	COG2814	Major facilitator Superfamily
MM522_01750	COG0488	(ABC) transporter
MM522_01755	COG0513	Belongs to the DEAD box helicase family
MM522_01760	COG0456	acetyltransferase
MM522_01765	COG2130	NADP-dependent
MM522_01770	COG2211	Major facilitator Superfamily
MM522_01775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MM522_01780	COG1120	ATPase activity
MM522_01785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM522_01790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM522_01795	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MM522_01810	COG3866	Pectate lyase
MM522_01815	COG0471	metal ion transport
MM522_01820	COG3290	protein histidine kinase activity
MM522_01825	COG4565	transcriptional regulatory protein
MM522_01830	COG3181	Tripartite tricarboxylate transporter family receptor
MM522_01835	COG2851	Citrate transporter
MM522_01840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM522_01845	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MM522_01850	COG1254	Belongs to the acylphosphatase family
MM522_01855	COG2258	MOSC domain
MM522_01875	COG0024	Methionine aminopeptidase
MM522_01880	COG1263	PTS System
MM522_01880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM522_01885	COG1368	sulfuric ester hydrolase activity
MM522_01900	COG1115	amino acid carrier protein
MM522_01905	COG0531	amino acid
MM522_01920	COG0697	spore germination
MM522_01925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM522_01925	COG1263	PTS System
MM522_01930	COG0366	Alpha amylase catalytic
MM522_01935	COG2188	Transcriptional regulator
MM522_01940	COG0778	Nitroreductase
MM522_01945	COG0737	Belongs to the 5'-nucleotidase family
MM522_01950	COG0693	protein deglycase activity
MM522_01955	COG2814	Major facilitator Superfamily
MM522_01960	COG4840	Belongs to the UPF0435 family
MM522_01965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MM522_01970	COG4980	gas vesicle protein
MM522_01975	COG1295	ribonuclease BN
MM522_01980	COG0477	Major facilitator Superfamily
MM522_01985	COG0387	Pfam Sodium calcium exchanger
MM522_01995	COG0668	transmembrane transport
MM522_02000	COG0535	radical SAM domain protein
MM522_02010	COG0726	polysaccharide deacetylase
MM522_02015	COG2084	Dehydrogenase
MM522_02020	COG0598	Magnesium transport protein CorA
MM522_02025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MM522_02030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MM522_02040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MM522_02045	COG4637	Psort location Cytoplasmic, score
MM522_02055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MM522_02060	COG0022	dehydrogenase e1 component
MM522_02065	COG0508	dehydrogenase complex catalyzes the overall conversion of
MM522_02070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MM522_02075	COG3284	Transcriptional regulator
MM522_02085	COG1742	UPF0060 membrane protein
MM522_02110	COG4842	Belongs to the WXG100 family
MM522_02115	COG1486	melibiose metabolic process
MM522_02120	COG1737	Transcriptional regulator
MM522_02125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM522_02125	COG1263	PTS System
MM522_02130	COG1132	(ABC) transporter
MM522_02135	COG1132	(ABC) transporter
MM522_02140	COG2259	Doxx family
MM522_02145	COG2514	catechol 2,3-dioxygenase activity
MM522_02150	COG4585	Histidine kinase
MM522_02155	COG2197	response regulator
MM522_02160	COG1131	(ABC) transporter
MM522_02165	COG1511	domain protein
MM522_02165	COG0842	Transport permease protein
MM522_02170	COG0842	Transport permease protein
MM522_02175	COG1695	Transcriptional regulator
MM522_02180	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MM522_02185	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MM522_02190	COG2318	DinB family
MM522_02195	COG2814	Major facilitator Superfamily
MM522_02200	COG1846	Transcriptional regulator
MM522_02205	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MM522_02205	COG0392	lysyltransferase activity
MM522_02210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MM522_02215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM522_02220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM522_02225	COG0384	phenazine biosynthesis protein PhzF
MM522_02230	COG0778	Nitroreductase
MM522_02245	COG1090	epimerase
MM522_02250	COG2137	regulation of response to DNA damage stimulus
MM522_02260	COG2814	Major facilitator Superfamily
MM522_02275	COG3103	Sh3 type 3 domain protein
MM522_02280	COG5658	integral membrane protein
MM522_02285	COG0596	Alpha beta hydrolase
MM522_02290	COG0463	Glycosyl transferase, family 2
MM522_02295	COG4485	Bacterial membrane protein, YfhO
MM522_02300	COG1988	membrane-bound metal-dependent
MM522_02305	COG1194	a g-specific adenine glycosylase
MM522_02315	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_02330	COG3557	Belongs to the UPF0374 family
MM522_02335	COG1132	(ABC) transporter
MM522_02340	COG4129	membrane
MM522_02345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MM522_02350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MM522_02355	COG0735	belongs to the Fur family
MM522_02465	COG4326	sporulation control protein
MM522_02475	COG5577	PFAM Coat F domain
MM522_02480	COG3340	Belongs to the peptidase S51 family
MM522_02485	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MM522_02490	COG0277	FAD linked oxidase domain protein
MM522_02500	COG0753	catalase activity
MM522_02505	COG1116	anion transmembrane transporter activity
MM522_02510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MM522_02515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MM522_02520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM522_02530	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MM522_02540	COG1476	TRANSCRIPTIONal
MM522_02550	COG3382	B3 4 domain protein
MM522_02555	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MM522_02565	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MM522_02570	COG0789	Transcriptional regulator
MM522_02575	COG1664	Polymer-forming cytoskeletal
MM522_02580	COG1664	Polymer-forming cytoskeletal
MM522_02585	COG2766	serine protein kinase
MM522_02590	COG2718	Belongs to the UPF0229 family
MM522_02595	COG1846	Transcriptional regulator
MM522_02600	COG1566	PFAM secretion protein HlyD family protein
MM522_02605	COG2814	Major facilitator Superfamily
MM522_02610	COG0655	NAD(P)H dehydrogenase (quinone) activity
MM522_02630	COG1725	Transcriptional regulator
MM522_02635	COG1131	(ABC) transporter
MM522_02640	COG1131	(ABC) transporter
MM522_02650	COG1278	Cold shock
MM522_02655	COG1464	Belongs to the NlpA lipoprotein family
MM522_02660	COG3706	GGDEF domain
MM522_02665	COG1823	symporter activity
MM522_02685	COG5577	PFAM Coat F domain
MM522_02690	COG4085	toxin activity
MM522_02690	COG0737	Belongs to the 5'-nucleotidase family
MM522_02690	COG1525	nuclease
MM522_02695	COG3764	Sortase (surface protein transpeptidase)
MM522_02700	COG0564	pseudouridine synthase activity
MM522_02710	COG0517	IMP dehydrogenase activity
MM522_02715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MM522_02720	COG3153	acetyltransferase
MM522_02720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MM522_02725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MM522_02730	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MM522_02735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MM522_02740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MM522_02745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MM522_02750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MM522_02755	COG4585	Histidine kinase
MM522_02755	COG2203	Gaf domain
MM522_02760	COG2197	response regulator
MM522_02765	COG0431	NADPH-dependent FMN reductase
MM522_02780	COG0791	NLP P60 protein
MM522_02780	COG1388	LysM domain
MM522_02785	COG1959	2 iron, 2 sulfur cluster binding
MM522_02790	COG0668	transmembrane transport
MM522_02795	COG2719	SpoVR family
MM522_02800	COG1785	Belongs to the alkaline phosphatase family
MM522_02805	COG1388	LysM domain
MM522_02805	COG0791	NLP P60 protein
MM522_02810	COG0583	DNA-binding transcription factor activity
MM522_02815	COG0372	Belongs to the citrate synthase family
MM522_02820	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_02825	COG0531	amino acid
MM522_02830	COG0733	neurotransmitter:sodium symporter activity
MM522_02835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM522_02840	COG0456	acetyltransferase
MM522_02855	COG1595	DNA-templated transcription, initiation
MM522_02860	COG0667	Aldo Keto reductase
MM522_02865	COG0204	Acyl-transferase
MM522_02870	COG1253	flavin adenine dinucleotide binding
MM522_02875	COG0789	Transcriptional regulator
MM522_02880	COG0436	Aminotransferase
MM522_02885	COG1253	flavin adenine dinucleotide binding
MM522_02890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MM522_02895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MM522_02900	COG0584	glycerophosphoryl diester phosphodiesterase
MM522_02910	COG0668	transmembrane transport
MM522_02915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MM522_02920	COG0726	polysaccharide deacetylase
MM522_02925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MM522_02930	COG1757	Na H antiporter
MM522_02935	COG0589	response to stress
MM522_02945	COG1132	(ABC) transporter
MM522_02950	COG1132	(ABC) transporter
MM522_02955	COG0702	epimerase
MM522_02975	COG0189	ligase activity
MM522_02980	COG0189	ligase activity
MM522_02985	COG4399	Belongs to the UPF0754 family
MM522_02990	COG3679	Belongs to the UPF0342 family
MM522_02995	COG4335	DNA alkylation repair
MM522_03000	COG0561	phosphatase activity
MM522_03005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MM522_03010	COG0475	glutathione-regulated potassium exporter activity
MM522_03015	COG0490	domain, Protein
MM522_03025	COG1024	Enoyl-CoA hydratase
MM522_03035	COG4152	abc transporter atp-binding protein
MM522_03040	COG1668	transmembrane transport
MM522_03045	COG0420	3'-5' exonuclease activity
MM522_03050	COG4717	serine-type aminopeptidase activity
MM522_03055	COG3481	metal-dependent phosphohydrolase, HD sub domain
MM522_03065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MM522_03095	COG1846	Transcriptional regulator
MM522_03100	COG4980	gas vesicle protein
MM522_03115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MM522_03120	COG0537	adenosine 5'-monophosphoramidase activity
MM522_03125	COG1131	(ABC) transporter
MM522_03130	COG4473	ABC transporter
MM522_03140	COG1473	amidohydrolase
MM522_03145	COG3069	C4-dicarboxylate transmembrane transporter activity
MM522_03155	COG2329	Antibiotic biosynthesis monooxygenase
MM522_03160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM522_03165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MM522_03170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MM522_03175	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MM522_03180	COG1309	transcriptional regulator
MM522_03185	COG1511	domain protein
MM522_03190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MM522_03195	COG4377	Putative membrane peptidase family (DUF2324)
MM522_03205	COG1363	Peptidase, m42
MM522_03210	COG4405	Protein conserved in bacteria
MM522_03215	COG1301	dicarboxylic acid transport
MM522_03225	COG1234	tRNA 3'-trailer cleavage
MM522_03230	COG0095	Lipoate-protein ligase
MM522_03235	COG0702	epimerase
MM522_03240	COG0318	PFAM AMP-dependent synthetase and ligase
MM522_03250	COG0501	Belongs to the peptidase M48B family
MM522_03260	COG0456	acetyltransferase
MM522_03265	COG0604	alcohol dehydrogenase
MM522_03270	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MM522_03275	COG0406	alpha-ribazole phosphatase activity
MM522_03280	COG0183	Belongs to the thiolase family
MM522_03285	COG0318	PFAM AMP-dependent synthetase and ligase
MM522_03290	COG1268	BioY protein
MM522_03295	COG0840	transmembrane signaling receptor activity
MM522_03300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MM522_03300	COG0723	plastoquinol--plastocyanin reductase activity
MM522_03305	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_03315	COG4903	ComK protein
MM522_03320	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_03330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MM522_03345	COG0398	Pfam SNARE associated Golgi protein
MM522_03350	COG0681	Belongs to the peptidase S26 family
MM522_03355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MM522_03360	COG1846	Transcriptional regulator
MM522_03365	COG0738	Major facilitator superfamily
MM522_03370	COG0673	inositol 2-dehydrogenase activity
MM522_03375	COG0561	phosphatase activity
MM522_03380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MM522_03385	COG1609	Transcriptional regulator
MM522_03390	COG3180	Ammonia monooxygenase
MM522_03395	COG2814	Major facilitator Superfamily
MM522_03395	COG0477	Major facilitator Superfamily
MM522_03400	COG4533	DNA binding
MM522_03410	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MM522_03420	COG1074	ATP-dependent DNA helicase activity
MM522_03425	COG0420	3'-5' exonuclease activity
MM522_03430	COG0419	ATPase involved in DNA repair
MM522_03435	COG1403	HNH endonuclease
MM522_03475	COG5337	Spore coat protein CotH
MM522_03480	COG0179	Fumarylacetoacetate (FAA) hydrolase
MM522_03490	COG1404	Belongs to the peptidase S8 family
MM522_03500	COG0367	asparagine synthase
MM522_03505	COG2318	DinB family
MM522_03510	COG1562	ergosterol biosynthetic process
MM522_03515	COG0534	Mate efflux family protein
MM522_03520	COG1917	Cupin 2, conserved barrel domain protein
MM522_03520	COG2207	Transcriptional regulator
MM522_03525	COG1609	Transcriptional regulator
MM522_03530	COG0673	inositol 2-dehydrogenase activity
MM522_03535	COG2318	DinB family
MM522_03545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM522_03550	COG1357	PFAM Pentapeptide repeats (8 copies)
MM522_03555	COG2267	carboxylic ester hydrolase activity
MM522_03560	COG0529	Catalyzes the synthesis of activated sulfate
MM522_03565	COG2046	Belongs to the sulfate adenylyltransferase family
MM522_03570	COG0175	sulfate reduction
MM522_03575	COG2045	Belongs to the ComB family
MM522_03580	COG1809	phosphosulfolactate synthase activity
MM522_03585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM522_03590	COG4948	Mandelate Racemase Muconate Lactonizing
MM522_03595	COG2814	Major facilitator Superfamily
MM522_03600	COG0454	-acetyltransferase
MM522_03610	COG0646	methionine synthase
MM522_03610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MM522_03615	COG1666	GTP binding
MM522_03620	COG2996	Protein conserved in bacteria
MM522_03640	COG1695	Transcriptional regulator
MM522_03655	COG3227	Zinc metalloprotease (Elastase)
MM522_03660	COG1307	EDD domain protein, DegV family
MM522_03665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM522_03685	COG0561	phosphatase activity
MM522_03690	COG1073	alpha beta
MM522_03695	COG2151	metal-sulfur cluster biosynthetic enzyme
MM522_03705	COG0277	FAD linked oxidase domain protein
MM522_03710	COG2271	Major facilitator Superfamily
MM522_03715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MM522_03720	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MM522_03730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MM522_03735	COG0505	Belongs to the CarA family
MM522_03740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MM522_03745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MM522_03760	COG2267	carboxylic ester hydrolase activity
MM522_03770	COG1744	ABC transporter substrate-binding protein PnrA-like
MM522_03785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MM522_03790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MM522_03795	COG5504	Zn-dependent protease
MM522_03800	COG0444	Belongs to the ABC transporter superfamily
MM522_03805	COG4608	Belongs to the ABC transporter superfamily
MM522_03815	COG0601	transmembrane transport
MM522_03820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM522_03830	COG0180	Tryptophanyl-tRNA synthetase
MM522_03835	COG4166	transmembrane transport
MM522_03840	COG0601	transmembrane transport
MM522_03845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM522_03850	COG0444	Belongs to the ABC transporter superfamily
MM522_03855	COG4608	Belongs to the ABC transporter superfamily
MM522_03860	COG2814	Major facilitator Superfamily
MM522_03865	COG0456	acetyltransferase
MM522_03870	COG1393	Belongs to the ArsC family
MM522_03875	COG0861	Integral membrane protein TerC family
MM522_03885	COG4862	establishment of competence for transformation
MM522_03895	COG4469	Competence protein
MM522_03900	COG1164	Oligoendopeptidase f
MM522_03910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MM522_03915	COG2346	COG2346, Truncated hemoglobins
MM522_03920	COG0741	lytic transglycosylase activity
MM522_03925	COG4116	CYTH
MM522_03935	COG2357	RelA SpoT domain protein
MM522_03940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MM522_03945	COG0564	pseudouridine synthase activity
MM522_03950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MM522_03955	COG0569	domain protein
MM522_03955	COG0475	glutathione-regulated potassium exporter activity
MM522_03960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MM522_03965	COG0352	thiamine-phosphate diphosphorylase activity
MM522_03970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MM522_03975	COG2104	thiamine diphosphate biosynthetic process
MM522_03980	COG2022	thiamine diphosphate biosynthetic process
MM522_03985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MM522_03990	COG0351	phosphomethylpyrimidine kinase
MM522_03995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MM522_04050	COG0210	DNA helicase
MM522_04060	COG2153	protein acetylation
MM522_04065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MM522_04070	COG2382	esterase
MM522_04075	COG0626	cystathionine gamma-synthase activity
MM522_04080	COG0626	cystathionine gamma-synthase activity
MM522_04085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM522_04090	COG5505	Protein of unknown function (DUF819)
MM522_04120	COG5444	nuclease activity
MM522_04145	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MM522_04150	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_04160	COG3711	transcriptional antiterminator
MM522_04160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM522_04165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MM522_04165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MM522_04165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM522_04170	COG1482	cell wall glycoprotein biosynthetic process
MM522_04180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM522_04190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MM522_04215	COG0726	polysaccharide deacetylase
MM522_04230	COG5504	Zn-dependent protease
MM522_04235	COG2205	protein histidine kinase activity
MM522_04245	COG3383	formate dehydrogenase (NAD+) activity
MM522_04250	COG2427	Protein of unknown function (DUF1641)
MM522_04260	COG1051	belongs to the nudix hydrolase family
MM522_04270	COG2124	cytochrome p450
MM522_04275	COG1819	glycosyl
MM522_04285	COG1587	Uroporphyrinogen-III synthase
MM522_04290	COG0390	transport system, permease component
MM522_04295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MM522_04300	COG0697	spore germination
MM522_04305	COG4297	protein containing double-stranded beta helix domain
MM522_04315	COG1252	NADH dehydrogenase
MM522_04320	COG1904	glucuronate isomerase
MM522_04325	COG2211	Major facilitator Superfamily
MM522_04330	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MM522_04335	COG1063	alcohol dehydrogenase
MM522_04340	COG1312	Catalyzes the dehydration of D-mannonate
MM522_04345	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_04350	COG2271	Major facilitator Superfamily
MM522_04355	COG1609	Transcriptional regulator
MM522_04360	COG0246	Mannitol dehydrogenase
MM522_04365	COG2721	sulfolactate sulfo-lyase activity
MM522_04370	COG0730	response to heat
MM522_04375	COG2318	DinB family
MM522_04380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM522_04385	COG0457	Tetratricopeptide repeat
MM522_04395	COG2350	Protein conserved in bacteria
MM522_04400	COG3409	Peptidoglycan-binding domain 1 protein
MM522_04400	COG5632	N-Acetylmuramoyl-L-alanine amidase
MM522_04400	COG1388	LysM domain
MM522_04410	COG4195	phage-related replication protein
MM522_04415	COG3546	catalase activity
MM522_04420	COG2856	Zn peptidase
MM522_04425	COG1396	sequence-specific DNA binding
MM522_04435	COG1522	sequence-specific DNA binding
MM522_04440	COG1484	DNA-dependent DNA replication
MM522_04460	COG1595	DNA-templated transcription, initiation
MM522_04465	COG5484	DNA packaging
MM522_04465	COG3728	DNA packaging
MM522_04470	COG1783	phage Terminase large subunit
MM522_04480	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MM522_04485	COG4653	Phage capsid family
MM522_04535	COG5412	phage tail tape measure protein
MM522_04535	COG3953	SLT domain
MM522_04540	COG1652	LysM domain
MM522_04545	COG4193	domain, Protein
MM522_04555	COG3628	GPW Gp25 family protein
MM522_04560	COG3299	homolog of phage Mu protein gp47
MM522_04565	COG3778	Protein conserved in bacteria
MM522_04605	COG3409	Peptidoglycan-binding domain 1 protein
MM522_04605	COG5632	N-Acetylmuramoyl-L-alanine amidase
MM522_04625	COG0306	phosphate transporter
MM522_04630	COG1392	Phosphate transport regulator
MM522_04640	COG0346	lactoylglutathione lyase activity
MM522_04650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MM522_04655	COG0463	Glycosyl transferase, family 2
MM522_04660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM522_04665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MM522_04670	COG2362	D-Aminopeptidase
MM522_04675	COG0601	transmembrane transport
MM522_04680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM522_04685	COG0444	Belongs to the ABC transporter superfamily
MM522_04690	COG4166	transmembrane transport
MM522_04695	COG1619	proteins homologs of microcin C7 resistance protein MccF
MM522_04700	COG4948	Mandelate Racemase Muconate Lactonizing
MM522_04705	COG0791	NLP P60 protein
MM522_04710	COG4608	Belongs to the ABC transporter superfamily
MM522_04715	COG2706	6-phosphogluconolactonase activity
MM522_04720	COG1834	amidinotransferase
MM522_04725	COG1607	acyl-coa hydrolase
MM522_04730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MM522_04730	COG1017	nitric oxide dioxygenase activity
MM522_04740	COG2323	membrane
MM522_04745	COG2318	DinB family
MM522_04750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM522_04755	COG2076	Multidrug Resistance protein
MM522_04760	COG2076	Multidrug Resistance protein
MM522_04765	COG0788	formyltetrahydrofolate deformylase activity
MM522_04770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MM522_04775	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MM522_04780	COG1764	response to oxidative stress
MM522_04785	COG1846	Transcriptional regulator
MM522_04790	COG1764	response to oxidative stress
MM522_04800	COG0590	tRNA wobble adenosine to inosine editing
MM522_04805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MM522_04810	COG1404	Belongs to the peptidase S8 family
MM522_04815	COG1366	Belongs to the anti-sigma-factor antagonist family
MM522_04820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MM522_04825	COG1122	ATPase activity
MM522_04830	COG4721	ABC-type cobalt transport system, permease component
MM522_04840	COG0745	RESPONSE REGULATOR receiver
MM522_04845	COG3850	Histidine kinase
MM522_04845	COG5002	protein histidine kinase activity
MM522_04850	COG3212	peptidase
MM522_04855	COG3212	peptidase
MM522_04865	COG2239	Acts as a magnesium transporter
MM522_04870	COG0789	Transcriptional regulator
MM522_04885	COG1846	Transcriptional regulator
MM522_04895	COG0726	polysaccharide deacetylase
MM522_04900	COG1408	metallophosphoesterase
MM522_04910	COG0463	Glycosyl transferase, family 2
MM522_04915	COG1793	dna ligase
MM522_04915	COG3285	dna ligase
MM522_04920	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MM522_04925	COG3300	MHYT domain
MM522_04925	COG5001	Diguanylate cyclase
MM522_04930	COG0586	Pfam SNARE associated Golgi protein
MM522_04935	COG0861	Integral membrane protein TerC family
MM522_04940	COG1191	sigma factor activity
MM522_04960	COG0501	Belongs to the peptidase M48B family
MM522_04965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MM522_04980	COG3594	Acyltransferase
MM522_04985	COG5002	protein histidine kinase activity
MM522_04990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MM522_05000	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MM522_05005	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MM522_05010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MM522_05015	COG0436	Aminotransferase
MM522_05020	COG1850	ribulose-bisphosphate carboxylase activity
MM522_05025	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MM522_05030	COG0235	Class ii aldolase
MM522_05035	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MM522_05040	COG3339	Conserved Protein
MM522_05055	COG3852	Histidine kinase
MM522_05060	COG1846	Transcriptional regulator
MM522_05065	COG1360	Flagellar Motor Protein
MM522_05070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MM522_05075	COG0542	response to heat
MM522_05080	COG3949	Membrane
MM522_05085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MM522_05090	COG0720	synthase
MM522_05095	COG0602	queuosine metabolic process
MM522_05100	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MM522_05105	COG1733	regulation of RNA biosynthetic process
MM522_05110	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_05115	COG4641	Protein conserved in bacteria
MM522_05115	COG1388	LysM domain
MM522_05120	COG1388	LysM domain
MM522_05125	COG3858	chitin binding
MM522_05135	COG4873	Protein conserved in bacteria
MM522_05145	COG3773	Cell wall hydrolase
MM522_05150	COG2244	polysaccharide biosynthetic process
MM522_05155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM522_05160	COG2217	Heavy metal translocating P-type atpase
MM522_05170	COG0006	proline dipeptidase activity
MM522_05175	COG1609	Transcriptional regulator
MM522_05180	COG3711	transcriptional antiterminator
MM522_05185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM522_05185	COG2190	(PTS) system
MM522_05185	COG1263	PTS System
MM522_05190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM522_05195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MM522_05205	COG1533	DNA photolyase activity
MM522_05210	COG0456	acetyltransferase
MM522_05215	COG0840	transmembrane signaling receptor activity
MM522_05220	COG2084	Dehydrogenase
MM522_05225	COG2340	Cysteine-rich secretory protein family
MM522_05230	COG0768	penicillin binding
MM522_05235	COG4191	Histidine kinase
MM522_05240	COG0436	Aminotransferase
MM522_05250	COG0835	chemotaxis
MM522_05250	COG0784	Response regulator, receiver
MM522_05260	COG2814	Major facilitator Superfamily
MM522_05265	COG1376	ErfK ybiS ycfS ynhG family protein
MM522_05270	COG1408	metallophosphoesterase
MM522_05275	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_05280	COG2200	EAL domain
MM522_05285	COG4703	Protein of unknown function (DUF1797)
MM522_05290	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MM522_05300	COG0517	IMP dehydrogenase activity
MM522_05305	COG0583	DNA-binding transcription factor activity
MM522_05310	COG0716	FMN binding
MM522_05320	COG0716	FMN binding
MM522_05325	COG2171	N-acyltransferase activity
MM522_05330	COG1473	amidohydrolase
MM522_05340	COG0668	transmembrane transport
MM522_05345	COG0450	alkyl hydroperoxide reductase
MM522_05350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM522_05365	COG0746	molybdenum cofactor guanylyltransferase activity
MM522_05370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MM522_05375	COG0303	'Molybdopterin
MM522_05380	COG1763	Mo-molybdopterin cofactor biosynthetic process
MM522_05385	COG0314	molybdopterin synthase activity
MM522_05390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MM522_05395	COG1132	(ABC) transporter
MM522_05400	COG1132	(ABC) transporter
MM522_05410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MM522_05415	COG1136	(ABC) transporter
MM522_05420	COG0577	efflux transmembrane transporter activity
MM522_05425	COG1349	DNA-binding transcription factor activity
MM522_05430	COG1105	Belongs to the carbohydrate kinase PfkB family
MM522_05435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MM522_05435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM522_05435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MM522_05440	COG0681	Belongs to the peptidase S26 family
MM522_05450	COG0488	(ABC) transporter
MM522_05455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MM522_05460	COG2309	aminopeptidase activity
MM522_05470	COG1077	Cell shape determining protein MreB Mrl
MM522_05475	COG2002	toxin-antitoxin pair type II binding
MM522_05480	COG3852	Histidine kinase
MM522_05485	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MM522_05485	COG2105	PFAM AIG2 family protein
MM522_05490	COG0569	domain protein
MM522_05495	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MM522_05500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MM522_05505	COG5503	Protein of unknown function (DUF1447)
MM522_05510	COG0561	phosphatase activity
MM522_05515	COG0242	peptide deformylase activity
MM522_05525	COG0497	DNA recombination
MM522_05530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MM522_05535	COG0022	dehydrogenase e1 component
MM522_05540	COG0508	dehydrogenase complex catalyzes the overall conversion of
MM522_05545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MM522_05550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM522_05560	COG1982	Orn Lys Arg decarboxylase major
MM522_05565	COG4476	Belongs to the UPF0223 family
MM522_05570	COG4493	Belongs to the UPF0637 family
MM522_05580	COG0483	inositol monophosphate 1-phosphatase activity
MM522_05590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM522_05610	COG1595	DNA-templated transcription, initiation
MM522_05630	COG1217	gtp-binding protein TYPA
MM522_05640	COG4896	Protein conserved in bacteria
MM522_05650	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MM522_05655	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MM522_05660	COG2066	Belongs to the glutaminase family
MM522_05665	COG4838	Belongs to the UPF0358 family
MM522_05670	COG0772	Belongs to the SEDS family
MM522_05675	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MM522_05680	COG1612	heme a metabolic process
MM522_05685	COG0109	protoheme IX farnesyltransferase activity
MM522_05690	COG2010	Cytochrome c
MM522_05690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MM522_05695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MM522_05700	COG1845	cytochrome c oxidase, subunit III
MM522_05705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MM522_05710	COG3336	cytochrome c oxidase
MM522_05720	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MM522_05725	COG2340	Cysteine-rich secretory protein family
MM522_05740	COG3679	Belongs to the UPF0342 family
MM522_05745	COG4471	UPF0298 protein
MM522_05750	COG0742	ribosomal rna small subunit methyltransferase
MM522_05755	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MM522_05760	COG3314	Sporulation integral membrane protein YlbJ
MM522_05765	COG1752	Esterase of the alpha-beta hydrolase superfamily
MM522_05770	COG3480	Lon protease (S16) C-terminal proteolytic domain
MM522_05775	COG1323	Belongs to the UPF0348 family
MM522_05785	COG1399	metal-binding, possibly nucleic acid-binding protein
MM522_05800	COG0454	-acetyltransferase
MM522_05805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MM522_05810	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MM522_05815	COG2001	Belongs to the MraZ family
MM522_05820	COG0275	rRNA processing
MM522_05825	COG4839	cell division protein FtsL
MM522_05830	COG0768	penicillin binding
MM522_05835	COG0768	penicillin binding
MM522_05840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MM522_05845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MM522_05850	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MM522_05855	COG0772	Belongs to the SEDS family
MM522_05860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MM522_05865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MM522_05870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MM522_05875	COG3879	Bacterial protein of unknown function (DUF881)
MM522_05880	COG3879	Bacterial protein of unknown function (DUF881)
MM522_05885	COG3856	small basic protein
MM522_05890	COG0849	cell division
MM522_05895	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MM522_05900	COG4412	M6 family metalloprotease domain protein
MM522_05900	COG1404	Belongs to the peptidase S8 family
MM522_05910	COG1191	sigma factor activity
MM522_05915	COG1191	sigma factor activity
MM522_05920	COG1119	ATPase activity
MM522_05925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MM522_05930	COG1873	PFAM PRC-barrel domain
MM522_05935	COG1496	oxidoreductase activity
MM522_05940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MM522_05945	COG1799	cell septum assembly
MM522_05950	COG0762	integral membrane protein
MM522_05955	COG2302	S4 RNA-binding domain
MM522_05960	COG3599	regulation of cell shape
MM522_05965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MM522_05970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MM522_05975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MM522_05980	COG0564	pseudouridine synthase activity
MM522_05985	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MM522_05990	COG2233	PERMEase
MM522_05995	COG0540	Belongs to the ATCase OTCase family
MM522_06000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MM522_06005	COG0505	Belongs to the CarA family
MM522_06010	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MM522_06015	COG0543	2 iron, 2 sulfur cluster binding
MM522_06020	COG0167	dihydroorotate dehydrogenase activity
MM522_06025	COG0284	orotidine-5'-phosphate decarboxylase activity
MM522_06030	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MM522_06035	COG0175	sulfate reduction
MM522_06040	COG0306	phosphate transporter
MM522_06045	COG2046	Belongs to the sulfate adenylyltransferase family
MM522_06050	COG0529	Catalyzes the synthesis of activated sulfate
MM522_06055	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MM522_06060	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
MM522_06065	COG1648	precorrin-2 dehydrogenase activity
MM522_06070	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MM522_06075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MM522_06080	COG1561	YicC-like family, N-terminal region
MM522_06090	COG0194	GDP metabolic process
MM522_06095	COG1758	RNA polymerase activity
MM522_06100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MM522_06105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MM522_06110	COG0242	peptide deformylase activity
MM522_06115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MM522_06120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MM522_06120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MM522_06125	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MM522_06130	COG0631	protein serine/threonine phosphatase activity
MM522_06135	COG0515	serine threonine protein kinase
MM522_06135	COG2815	serine threonine protein kinase
MM522_06140	COG1162	GTPase activity
MM522_06145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MM522_06150	COG1564	THIamine pyrophosphokinase
MM522_06160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MM522_06165	COG1302	Protein conserved in bacteria
MM522_06170	COG1461	Dihydroxyacetone kinase
MM522_06175	COG1760	l-serine dehydratase
MM522_06180	COG1760	l-serine dehydratase
MM522_06185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MM522_06190	COG2050	protein possibly involved in aromatic compounds catabolism
MM522_06190	COG1349	DNA-binding transcription factor activity
MM522_06195	COG0416	fatty acid biosynthetic process
MM522_06200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MM522_06205	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_06215	COG0571	ribonuclease III activity
MM522_06220	COG1196	nuclear chromosome segregation
MM522_06225	COG0552	protein localization to endoplasmic reticulum
MM522_06235	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MM522_06240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MM522_06245	COG0228	four-way junction DNA binding
MM522_06250	COG1837	Belongs to the UPF0109 family
MM522_06260	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MM522_06265	COG0336	Belongs to the RNA methyltransferase TrmD family
MM522_06270	COG0335	large ribosomal subunit rRNA binding
MM522_06275	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MM522_06280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MM522_06290	COG2257	FlhB HrpN YscU SpaS Family
MM522_06295	COG0045	succinate-CoA ligase (ADP-forming) activity
MM522_06300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MM522_06305	COG0758	DNA mediated transformation
MM522_06310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MM522_06315	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MM522_06320	COG4974	Belongs to the 'phage' integrase family
MM522_06325	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MM522_06330	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MM522_06335	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MM522_06340	COG1815	bacterial-type flagellum-dependent cell motility
MM522_06345	COG1558	bacterial-type flagellum-dependent cell motility
MM522_06350	COG1677	Flagellar hook-basal body complex protein FliE
MM522_06355	COG1766	The M ring may be actively involved in energy transduction
MM522_06360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MM522_06365	COG1317	bacterial-type flagellum organization
MM522_06370	COG1157	protein secretion by the type III secretion system
MM522_06375	COG2882	bacterial-type flagellum organization
MM522_06380	COG3334	PFAM MgtE intracellular
MM522_06385	COG3144	bacterial-type flagellum assembly
MM522_06390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MM522_06395	COG4786	Flagellar basal body rod
MM522_06400	COG1582	Flagellar protein (FlbD)
MM522_06405	COG1580	Controls the rotational direction of flagella during chemotaxis
MM522_06410	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MM522_06415	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MM522_06415	COG1776	CheC inhibitor of MCP methylation
MM522_06420	COG2201	protein-glutamate methylesterase activity
MM522_06425	COG3190	flagellar
MM522_06430	COG1338	Plays a role in the flagellum-specific transport system
MM522_06435	COG1987	bacterial-type flagellum assembly
MM522_06440	COG1684	flagellar biosynthetic protein fliR
MM522_06445	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MM522_06450	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MM522_06455	COG1419	protein localization to endoplasmic reticulum
MM522_06460	COG0455	bacterial-type flagellum organization
MM522_06465	COG2201	protein-glutamate methylesterase activity
MM522_06470	COG2198	Histidine kinase
MM522_06470	COG0643	Histidine kinase
MM522_06475	COG0835	chemotaxis
MM522_06480	COG1776	CheC inhibitor of MCP methylation
MM522_06485	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MM522_06490	COG1191	sigma factor activity
MM522_06500	COG0052	Belongs to the universal ribosomal protein uS2 family
MM522_06505	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MM522_06510	COG0528	UMP kinase activity
MM522_06515	COG0233	cytoplasmic translational termination
MM522_06520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MM522_06525	COG4589	Belongs to the CDS family
MM522_06530	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MM522_06535	COG0750	zinc metalloprotease
MM522_06540	COG0442	prolyl-tRNA aminoacylation
MM522_06545	COG2176	DNA-directed DNA polymerase activity
MM522_06550	COG0779	Required for maturation of 30S ribosomal subunits
MM522_06555	COG0195	Participates in both transcription termination and antitermination
MM522_06560	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MM522_06565	COG1358	cellular component organization or biogenesis
MM522_06570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MM522_06575	COG1550	Protein conserved in bacteria
MM522_06580	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MM522_06585	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MM522_06590	COG0196	riboflavin kinase activity
MM522_06595	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MM522_06600	COG1185	polyribonucleotide nucleotidyltransferase activity
MM522_06605	COG0726	polysaccharide deacetylase
MM522_06610	COG0612	Peptidase, M16
MM522_06615	COG1873	PFAM PRC-barrel domain
MM522_06620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MM522_06625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MM522_06630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MM522_06635	COG0527	aspartate kinase activity
MM522_06640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MM522_06645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MM522_06650	COG0740	serine-type endopeptidase activity
MM522_06660	COG4980	gas vesicle protein
MM522_06660	COG1674	ftsk spoiiie
MM522_06665	COG2188	Transcriptional regulator
MM522_06670	COG2814	Major facilitator Superfamily
MM522_06675	COG0612	Peptidase, M16
MM522_06680	COG0612	Peptidase, M16
MM522_06685	COG0300	oxidoreductase activity
MM522_06700	COG1426	Protein conserved in bacteria
MM522_06705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MM522_06710	COG1546	Belongs to the CinA family
MM522_06710	COG1058	Belongs to the CinA family
MM522_06715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MM522_06720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MM522_06725	COG1418	mRNA catabolic process
MM522_06730	COG1692	metallophosphoesterase
MM522_06735	COG2359	stage V sporulation protein S
MM522_06740	COG1063	alcohol dehydrogenase
MM522_06745	COG0156	8-amino-7-oxononanoate synthase activity
MM522_06750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MM522_06755	COG4550	Control of competence regulator ComK, YlbF/YmcA
MM522_06765	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MM522_06770	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MM522_06785	COG3226	Transcriptional regulator
MM522_06790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM522_06800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MM522_06805	COG3321	synthase
MM522_06810	COG2070	2-Nitropropane dioxygenase
MM522_06810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MM522_06815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM522_06820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MM522_06825	COG3425	synthase
MM522_06830	COG1024	Enoyl-CoA hydratase
MM522_06835	COG1024	Enoyl-CoA hydratase
MM522_06840	COG3321	synthase
MM522_06840	COG0300	oxidoreductase activity
MM522_06840	COG0318	PFAM AMP-dependent synthetase and ligase
MM522_06840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_06840	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_06845	COG0300	oxidoreductase activity
MM522_06845	COG4221	oxidoreductase activity
MM522_06845	COG3321	synthase
MM522_06845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM522_06850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM522_06850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MM522_06850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_06850	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_06850	COG3321	synthase
MM522_06855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_06855	COG3321	synthase
MM522_06855	COG4221	oxidoreductase activity
MM522_06855	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_06860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MM522_06860	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MM522_06860	COG3321	synthase
MM522_06860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM522_06865	COG2124	cytochrome p450
MM522_06875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM522_06880	COG1404	Belongs to the peptidase S8 family
MM522_06890	COG4195	phage-related replication protein
MM522_06895	COG1764	response to oxidative stress
MM522_06900	COG2076	Multidrug Resistance protein
MM522_06905	COG2076	Multidrug Resistance protein
MM522_06920	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MM522_06925	COG1923	regulation of RNA biosynthetic process
MM522_06940	COG1780	Probably involved in ribonucleotide reductase function
MM522_06945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MM522_06950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MM522_06955	COG4112	unkown
MM522_06960	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM522_06965	COG0464	growth
MM522_06970	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MM522_06975	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MM522_06980	COG0789	Transcriptional regulator
MM522_06985	COG0174	glutamine synthetase
MM522_07005	COG4824	toxin secretion phage lysis holin
MM522_07015	COG0463	Glycosyl transferase, family 2
MM522_07035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM522_07050	COG3655	Transcriptional regulator
MM522_07065	COG0135	phosphoribosylanthranilate isomerase activity
MM522_07070	COG2211	Major facilitator Superfamily
MM522_07075	COG3507	Belongs to the glycosyl hydrolase 43 family
MM522_07080	COG1940	carbohydrate kinase activity
MM522_07085	COG2115	Belongs to the xylose isomerase family
MM522_07090	COG1070	Carbohydrate kinase
MM522_07100	COG1525	nuclease
MM522_07105	COG2814	Major facilitator Superfamily
MM522_07110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MM522_07120	COG0756	dUTP diphosphatase activity
MM522_07160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MM522_07175	COG3832	glyoxalase III activity
MM522_07185	COG0697	spore germination
MM522_07190	COG0531	amino acid
MM522_07220	COG4195	phage-related replication protein
MM522_07230	COG0346	lactoylglutathione lyase activity
MM522_07240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MM522_07245	COG1388	LysM domain
MM522_07250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MM522_07255	COG4224	UPF0291 protein
MM522_07260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MM522_07270	COG3763	UPF0154 protein
MM522_07280	COG0785	Cytochrome C biogenesis protein
MM522_07285	COG2201	protein-glutamate methylesterase activity
MM522_07290	COG4846	Membrane protein involved in cytochrome C biogenesis
MM522_07300	COG0071	Belongs to the small heat shock protein (HSP20) family
MM522_07315	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MM522_07320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM522_07340	COG0824	Thioesterase
MM522_07350	COG4841	protein insertion into membrane
MM522_07355	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MM522_07360	COG1832	CoA-binding protein
MM522_07365	COG0187	DNA topoisomerase II activity
MM522_07380	COG1115	amino acid carrier protein
MM522_07385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MM522_07395	COG5520	Belongs to the glycosyl hydrolase 30 family
MM522_07400	COG3507	Belongs to the glycosyl hydrolase 43 family
MM522_07405	COG2246	polysaccharide biosynthetic process
MM522_07410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MM522_07415	COG0586	Pfam SNARE associated Golgi protein
MM522_07420	COG2404	hydrolase activity, acting on ester bonds
MM522_07425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MM522_07430	COG1024	Enoyl-CoA hydratase
MM522_07435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MM522_07440	COG0511	ligase activity, forming carbon-carbon bonds
MM522_07445	COG0439	Biotin carboxylase
MM522_07450	COG0318	PFAM AMP-dependent synthetase and ligase
MM522_07455	COG1960	acyl-CoA dehydrogenase activity
MM522_07470	COG1649	PFAM Uncharacterised BCR, COG1649
MM522_07480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_07480	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MM522_07495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_07505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_07515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_07520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_07525	COG2027	D-alanyl-D-alanine carboxypeptidase
MM522_07530	COG2017	converts alpha-aldose to the beta-anomer
MM522_07535	COG0534	Mate efflux family protein
MM522_07550	COG0582	viral genome integration into host DNA
MM522_07555	COG0166	Belongs to the GPI family
MM522_07560	COG0405	Gamma-glutamyltransferase
MM522_07565	COG0583	DNA-binding transcription factor activity
MM522_07570	COG0604	alcohol dehydrogenase
MM522_07585	COG0583	DNA-binding transcription factor activity
MM522_07590	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MM522_07595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MM522_07605	COG0300	oxidoreductase activity
MM522_07610	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MM522_07620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM522_07640	COG2814	Major facilitator Superfamily
MM522_07645	COG1070	Carbohydrate kinase
MM522_07650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MM522_07655	COG0243	molybdopterin cofactor binding
MM522_07685	COG5278	phosphoserine phosphatase activity
MM522_07685	COG0840	transmembrane signaling receptor activity
MM522_07690	COG2368	4-hydroxyphenylacetate
MM522_07695	COG4305	rare lipoprotein A
MM522_07700	COG3619	membrane
MM522_07705	COG3866	Pectate lyase
MM522_07710	COG2135	peptidase activity
MM522_07720	COG2140	Oxalate decarboxylase
MM522_07735	COG0456	acetyltransferase
MM522_07755	COG2720	vancomycin resistance protein
MM522_07765	COG3655	Transcriptional regulator
MM522_07770	COG3739	integral membrane protein
MM522_07775	COG0583	DNA-binding transcription factor activity
MM522_07780	COG0697	spore germination
MM522_07790	COG0693	protein deglycase activity
MM522_07795	COG2367	Beta-lactamase
MM522_07810	COG0574	Belongs to the PEP-utilizing enzyme family
MM522_07810	COG3848	Pyruvate phosphate dikinase
MM522_07815	COG0726	polysaccharide deacetylase
MM522_07825	COG2314	TM2 domain
MM522_07830	COG1396	sequence-specific DNA binding
MM522_07875	COG2723	6-phospho-beta-galactosidase activity
MM522_07895	COG0395	ABC-type sugar transport system, permease component
MM522_07900	COG1175	transmembrane transport
MM522_07910	COG1940	carbohydrate kinase activity
MM522_07925	COG5444	nuclease activity
MM522_07930	COG4282	regulation of fungal-type cell wall biogenesis
MM522_07935	COG1231	oxidoreductase activity
MM522_07940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM522_07945	COG0662	Cupin 2, conserved barrel domain protein
MM522_07945	COG2207	Transcriptional regulator
MM522_07950	COG0456	acetyltransferase
MM522_07955	COG1309	transcriptional regulator
MM522_07960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM522_07965	COG3708	Transcriptional regulator
MM522_07970	COG2378	regulation of single-species biofilm formation
MM522_07980	COG0640	Transcriptional regulator
MM522_07985	COG0741	lytic transglycosylase activity
MM522_07990	COG2322	membrane
MM522_08005	COG1619	proteins homologs of microcin C7 resistance protein MccF
MM522_08010	COG3239	Fatty acid desaturase
MM522_08015	COG4585	Histidine kinase
MM522_08020	COG2197	response regulator
MM522_08025	COG1388	LysM domain
MM522_08025	COG3584	3D domain protein
MM522_08030	COG0514	ATP-dependent DNA helicase (RecQ)
MM522_08040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MM522_08045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MM522_08060	COG0071	Belongs to the small heat shock protein (HSP20) family
MM522_08085	COG1012	belongs to the aldehyde dehydrogenase family
MM522_08090	COG1657	PFAM Prenyltransferase squalene oxidase
MM522_08095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MM522_08100	COG0733	neurotransmitter:sodium symporter activity
MM522_08105	COG0385	Bile acid
MM522_08110	COG0508	dehydrogenase complex catalyzes the overall conversion of
MM522_08115	COG0567	Dehydrogenase, E1 component
MM522_08120	COG4548	von Willebrand factor, type A
MM522_08125	COG0714	Associated with various cellular activities
MM522_08130	COG2032	superoxide dismutase activity
MM522_08135	COG1388	LysM domain
MM522_08135	COG0791	NLP P60 protein
MM522_08140	COG1819	glycosyl
MM522_08145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MM522_08150	COG0534	Mate efflux family protein
MM522_08155	COG1366	Belongs to the anti-sigma-factor antagonist family
MM522_08160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MM522_08165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MM522_08175	COG2962	Rard protein
MM522_08190	COG2610	gluconate transmembrane transporter activity
MM522_08195	COG1942	4-Oxalocrotonate Tautomerase
MM522_08200	COG1733	regulation of RNA biosynthetic process
MM522_08205	COG0778	Nitroreductase
MM522_08210	COG0400	carboxylic ester hydrolase activity
MM522_08215	COG0346	lactoylglutathione lyase activity
MM522_08225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MM522_08230	COG3409	Peptidoglycan-binding domain 1 protein
MM522_08230	COG0793	Belongs to the peptidase S41A family
MM522_08235	COG2226	methyltransferase
MM522_08245	COG1876	peptidase activity
MM522_08250	COG0813	purine-nucleoside phosphorylase activity
MM522_08265	COG0671	phosphoesterase, PA-phosphatase related
MM522_08285	COG4479	Belongs to the UPF0346 family
MM522_08295	COG1509	lysine 2,3-aminomutase activity
MM522_08300	COG0456	acetyltransferase
MM522_08305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MM522_08310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MM522_08315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MM522_08320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MM522_08335	COG0456	acetyltransferase
MM522_08340	COG0463	Glycosyl transferase, family 2
MM522_08355	COG4641	Protein conserved in bacteria
MM522_08360	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
MM522_08365	COG1086	Polysaccharide biosynthesis protein
MM522_08370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MM522_08375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MM522_08380	COG1846	Transcriptional regulator
MM522_08385	COG0534	Mate efflux family protein
MM522_08395	COG4698	Protein conserved in bacteria
MM522_08400	COG2755	lipolytic protein G-D-S-L family
MM522_08405	COG1999	signal sequence binding
MM522_08415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MM522_08425	COG1272	protein, Hemolysin III
MM522_08430	COG0204	Acyl-transferase
MM522_08435	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MM522_08440	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MM522_08445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MM522_08455	COG2136	Putative SAM-dependent methyltransferase
MM522_08455	COG2521	methyltransferase
MM522_08465	COG0129	dihydroxy-acid dehydratase activity
MM522_08470	COG1413	lyase activity
MM522_08475	COG1418	mRNA catabolic process
MM522_08480	COG0386	Belongs to the glutathione peroxidase family
MM522_08485	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MM522_08490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MM522_08500	COG1278	Cold shock
MM522_08520	COG0328	RNA-DNA hybrid ribonuclease activity
MM522_08525	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MM522_08530	COG0328	RNA-DNA hybrid ribonuclease activity
MM522_08540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MM522_08555	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MM522_08565	COG1755	Isoprenylcysteine carboxyl methyltransferase
MM522_08570	COG3424	synthase
MM522_08575	COG2233	PERMEase
MM522_08580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MM522_08585	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MM522_08595	COG0800	Aldolase
MM522_08600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM522_08605	COG1609	Transcriptional regulator
MM522_08610	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MM522_08615	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_08620	COG1199	ATP-dependent helicase activity
MM522_08635	COG0116	Belongs to the methyltransferase superfamily
MM522_08650	COG4474	Belongs to the UPF0398 family
MM522_08665	COG3359	exonuclease
MM522_08670	COG1111	helicase
MM522_08670	COG1205	dead DEAH box helicase
MM522_08675	COG2190	(PTS) system
MM522_08680	COG0071	Belongs to the small heat shock protein (HSP20) family
MM522_08715	COG3331	DNA recombination
MM522_08720	COG4499	WXG100 protein secretion system (Wss), protein YukC
MM522_08720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM522_08730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MM522_08735	COG3935	DnaD domain protein
MM522_08740	COG0017	Asparaginyl-tRNA synthetase
MM522_08745	COG0436	Aminotransferase
MM522_08750	COG5353	protein conserved in bacteria
MM522_08760	COG1199	ATP-dependent helicase activity
MM522_08760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MM522_08765	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MM522_08770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MM522_08775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MM522_08780	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MM522_08780	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MM522_08785	COG0617	tRNA 3'-terminal CCA addition
MM522_08790	COG0438	transferase activity, transferring glycosyl groups
MM522_08795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MM522_08800	COG1803	Methylglyoxal synthase
MM522_08805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MM522_08810	COG1694	Mazg nucleotide pyrophosphohydrolase
MM522_08815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM522_08825	COG4347	Protein of unknown function (DUF1405)
MM522_08830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MM522_08830	COG2010	Cytochrome c
MM522_08835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MM522_08840	COG0723	plastoquinol--plastocyanin reductase activity
MM522_08850	COG5582	Belongs to the UPF0302 family
MM522_08855	COG0457	Tetratricopeptide repeat
MM522_08860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MM522_08865	COG0287	Prephenate dehydrogenase
MM522_08870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MM522_08875	COG0159	tryptophan synthase activity
MM522_08880	COG0133	tryptophan synthase activity
MM522_08885	COG0135	phosphoribosylanthranilate isomerase activity
MM522_08895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MM522_08900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MM522_08905	COG4401	Chorismate mutase type I
MM522_08910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MM522_08915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MM522_08920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MM522_08925	COG0105	UTP biosynthetic process
MM522_08930	COG0142	geranyltranstransferase activity
MM522_08935	COG2226	methyltransferase
MM522_08940	COG0142	geranyltranstransferase activity
MM522_08950	COG0302	gtp cyclohydrolase
MM522_08955	COG0776	regulation of translation
MM522_08960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MM522_08975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MM522_08980	COG1160	GTP binding
MM522_09005	COG1304	FMN binding
MM522_09010	COG0539	negative regulation of cytoplasmic translation
MM522_09015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MM522_09025	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MM522_09030	COG2959	enzyme of heme biosynthesis
MM522_09035	COG3773	Cell wall hydrolase
MM522_09035	COG3409	Peptidoglycan-binding domain 1 protein
MM522_09040	COG2339	peptidase activity
MM522_09045	COG0492	ferredoxin-NADP+ reductase activity
MM522_09050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MM522_09055	COG4862	establishment of competence for transformation
MM522_09060	COG1408	metallophosphoesterase
MM522_09070	COG1388	LysM domain
MM522_09075	COG1266	CAAX protease self-immunity
MM522_09080	COG0514	ATP-dependent DNA helicase (RecQ)
MM522_09085	COG4955	Helix-turn-helix domain
MM522_09090	COG1141	Ferredoxin
MM522_09095	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MM522_09100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MM522_09105	COG0710	3-dehydroquinate dehydratase activity
MM522_09115	COG1595	DNA-templated transcription, initiation
MM522_09120	COG5002	protein histidine kinase activity
MM522_09125	COG0745	RESPONSE REGULATOR receiver
MM522_09130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MM522_09135	COG1333	cytochrome c biogenesis protein
MM522_09140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM522_09145	COG1187	pseudouridine synthase activity
MM522_09150	COG0700	Nucleoside recognition
MM522_09155	COG2715	membrane protein required for spore maturation
MM522_09160	COG1686	Belongs to the peptidase S11 family
MM522_09170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MM522_09175	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MM522_09180	COG1547	Domain of unknown function (DUF309)
MM522_09185	COG0456	acetyltransferase
MM522_09190	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MM522_09195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MM522_09195	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MM522_09200	COG0307	riboflavin synthase, alpha
MM522_09205	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MM522_09205	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MM522_09215	COG0681	Belongs to the peptidase S26 family
MM522_09225	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MM522_09240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MM522_09245	COG4086	secreted protein
MM522_09250	COG0019	diaminopimelate decarboxylase activity
MM522_09255	COG0697	spore germination
MM522_09270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MM522_09290	COG1191	sigma factor activity
MM522_09295	COG2172	sigma factor antagonist activity
MM522_09300	COG1366	Belongs to the anti-sigma-factor antagonist family
MM522_09305	COG1686	Belongs to the peptidase S11 family
MM522_09310	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MM522_09315	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MM522_09320	COG4974	Belongs to the 'phage' integrase family
MM522_09330	COG0735	belongs to the Fur family
MM522_09335	COG1300	Membrane
MM522_09345	COG0281	malic enzyme
MM522_09350	COG1757	Na H antiporter
MM522_09355	COG1027	Aspartate ammonia-lyase
MM522_09360	COG0252	asparaginase activity
MM522_09365	COG1396	sequence-specific DNA binding
MM522_09370	COG1379	DNA repair
MM522_09375	COG0494	nUDIX hydrolase
MM522_09385	COG0667	Aldo Keto reductase
MM522_09395	COG1073	alpha beta
MM522_09405	COG4918	Iron-sulphur cluster biosynthesis
MM522_09410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MM522_09410	COG0456	acetyltransferase
MM522_09415	COG2329	Antibiotic biosynthesis monooxygenase
MM522_09420	COG0456	acetyltransferase
MM522_09430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MM522_09440	COG2211	Major facilitator Superfamily
MM522_09450	COG0346	lactoylglutathione lyase activity
MM522_09455	COG1072	(Pantothenic acid kinase))
MM522_09460	COG3048	D-serine ammonia-lyase activity
MM522_09465	COG0300	oxidoreductase activity
MM522_09470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM522_09475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MM522_09480	COG4187	Peptidase family M20/M25/M40
MM522_09485	COG1902	pentaerythritol trinitrate reductase activity
MM522_09490	COG0596	Alpha beta hydrolase
MM522_09500	COG1234	tRNA 3'-trailer cleavage
MM522_09505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MM522_09510	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MM522_09515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MM522_09525	COG0706	membrane insertase activity
MM522_09530	COG3361	conserved protein (COG2071)
MM522_09535	COG2195	Cleaves the N-terminal amino acid of tripeptides
MM522_09540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MM522_09545	COG0346	lactoylglutathione lyase activity
MM522_09555	COG1376	ErfK ybiS ycfS ynhG family protein
MM522_09560	COG4129	membrane
MM522_09565	COG1126	abc transporter atp-binding protein
MM522_09570	COG0765	amino acid transport
MM522_09575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM522_09585	COG1597	lipid kinase activity
MM522_09590	COG2814	Major facilitator Superfamily
MM522_09595	COG4978	Transcriptional regulator
MM522_09595	COG0789	Transcriptional regulator
MM522_09600	COG0508	dehydrogenase complex catalyzes the overall conversion of
MM522_09605	COG0022	dehydrogenase e1 component
MM522_09610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MM522_09615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MM522_09620	COG3426	butyrate kinase activity
MM522_09625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MM522_09630	COG0280	phosphate acetyltransferase
MM522_09635	COG3290	protein histidine kinase activity
MM522_09635	COG3829	transcription factor binding
MM522_09645	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MM522_09650	COG2079	MmgE PrpD family protein
MM522_09655	COG0372	Belongs to the citrate synthase family
MM522_09660	COG1960	acyl-CoA dehydrogenase activity
MM522_09670	COG0183	Belongs to the thiolase family
MM522_09675	COG0584	glycerophosphoryl diester phosphodiesterase
MM522_09680	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM522_09695	COG1902	pentaerythritol trinitrate reductase activity
MM522_09700	COG0745	RESPONSE REGULATOR receiver
MM522_09705	COG0750	zinc metalloprotease
MM522_09710	COG0497	DNA recombination
MM522_09715	COG1438	arginine binding
MM522_09720	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MM522_09725	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MM522_09730	COG0142	geranyltranstransferase activity
MM522_09735	COG1722	exodeoxyribonuclease VII activity
MM522_09740	COG1570	exodeoxyribonuclease VII activity
MM522_09745	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MM522_09750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MM522_09755	COG1302	Protein conserved in bacteria
MM522_09760	COG0439	Biotin carboxylase
MM522_09765	COG0511	ligase activity, forming carbon-carbon bonds
MM522_09805	COG3854	ATPases associated with a variety of cellular activities
MM522_09815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MM522_09820	COG0006	proline dipeptidase activity
MM522_09825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MM522_09835	COG3872	metal-dependent enzyme
MM522_09845	COG1752	Esterase of the alpha-beta hydrolase superfamily
MM522_09850	COG1321	iron dependent repressor
MM522_09855	COG0095	Lipoate-protein ligase
MM522_09860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MM522_09865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MM522_09870	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MM522_09875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MM522_09880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MM522_09895	COG1396	sequence-specific DNA binding
MM522_09905	COG0681	Belongs to the peptidase S26 family
MM522_09930	COG4940	Competence protein ComGF
MM522_09940	COG4970	Tfp pilus assembly protein FimT
MM522_09945	COG4537	Required for transformation and DNA binding
MM522_09950	COG1459	type II secretion system
MM522_09955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MM522_09960	COG0517	IMP dehydrogenase activity
MM522_09965	COG0598	Magnesium transport protein CorA
MM522_09970	COG1253	flavin adenine dinucleotide binding
MM522_09975	COG1366	Belongs to the anti-sigma-factor antagonist family
MM522_09985	COG1393	Belongs to the ArsC family
MM522_09995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM522_10005	COG0011	TIGRFAM Protein of
MM522_10015	COG2866	Carboxypeptidase
MM522_10020	COG1368	sulfuric ester hydrolase activity
MM522_10025	COG1940	carbohydrate kinase activity
MM522_10030	COG4483	Protein conserved in bacteria
MM522_10035	COG0705	Rhomboid family
MM522_10035	COG0457	Tetratricopeptide repeat
MM522_10045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MM522_10055	COG0438	transferase activity, transferring glycosyl groups
MM522_10070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MM522_10075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MM522_10080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MM522_10085	COG0581	inorganic phosphate transmembrane transporter activity
MM522_10090	COG0573	inorganic phosphate transmembrane transporter activity
MM522_10095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MM522_10100	COG0768	penicillin binding
MM522_10105	COG0477	Major facilitator Superfamily
MM522_10110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MM522_10115	COG2839	Protein conserved in bacteria
MM522_10120	COG5521	maltodextrose utilization protein MalA
MM522_10125	COG1388	LysM domain
MM522_10130	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MM522_10135	COG4709	membrane
MM522_10140	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
MM522_10145	COG0735	belongs to the Fur family
MM522_10150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM522_10160	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MM522_10165	COG0513	Belongs to the DEAD box helicase family
MM522_10175	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MM522_10180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MM522_10185	COG2384	SAM-dependent methyltransferase
MM522_10190	COG2010	Cytochrome c
MM522_10195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MM522_10200	COG0358	DNA primase activity
MM522_10205	COG1671	Belongs to the UPF0178 family
MM522_10210	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MM522_10215	COG0517	IMP dehydrogenase activity
MM522_10220	COG0751	glycine-tRNA ligase activity
MM522_10225	COG0752	glycyl-tRNA synthetase alpha subunit
MM522_10230	COG1381	Involved in DNA repair and RecF pathway recombination
MM522_10240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MM522_10245	COG0295	cytidine deaminase activity
MM522_10250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MM522_10255	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MM522_10260	COG1480	7TM receptor with intracellular HD hydrolase
MM522_10265	COG1702	phosphate starvation-inducible protein PhoH
MM522_10270	COG0561	phosphatase activity
MM522_10285	COG4864	UPF0365 protein
MM522_10290	COG1030	water channel activity
MM522_10295	COG1610	YqeY-like protein
MM522_10305	COG1283	sodium-dependent phosphate transmembrane transporter activity
MM522_10310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MM522_10315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MM522_10320	COG2264	protein methyltransferase activity
MM522_10325	COG0484	heat shock protein binding
MM522_10330	COG0443	Heat shock 70 kDa protein
MM522_10335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MM522_10340	COG1420	regulation of RNA biosynthetic process
MM522_10345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MM522_10350	COG0481	GTPase activity
MM522_10360	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM522_10365	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MM522_10370	COG0268	Binds directly to 16S ribosomal RNA
MM522_10375	COG1466	dna polymerase III delta subunit
MM522_10390	COG2333	competence protein COMEC
MM522_10390	COG0658	competence protein
MM522_10395	COG2131	deaminase
MM522_10400	COG1596	polysaccharide export
MM522_10400	COG1555	photosystem II stabilization
MM522_10405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MM522_10410	COG2226	methyltransferase
MM522_10415	COG0799	negative regulation of ribosome biogenesis
MM522_10420	COG1713	HD superfamily hydrolase involved in NAD metabolism
MM522_10425	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MM522_10430	COG1534	Rna-binding protein
MM522_10435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MM522_10440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MM522_10445	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MM522_10455	COG2755	lipolytic protein G-D-S-L family
MM522_10460	COG5632	N-Acetylmuramoyl-L-alanine amidase
MM522_10460	COG3409	Peptidoglycan-binding domain 1 protein
MM522_10465	COG0398	Pfam SNARE associated Golgi protein
MM522_10470	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MM522_10480	COG3209	COG3209 Rhs family protein
MM522_10490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MM522_10500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MM522_10505	COG0798	PFAM Bile acid sodium symporter
MM522_10510	COG0346	lactoylglutathione lyase activity
MM522_10515	COG0640	Transcriptional regulator
MM522_10520	COG3403	YqcI/YcgG family
MM522_10525	COG0457	Tetratricopeptide repeat
MM522_10540	COG5444	nuclease activity
MM522_10565	COG3409	Peptidoglycan-binding domain 1 protein
MM522_10565	COG5632	N-Acetylmuramoyl-L-alanine amidase
MM522_10570	COG4824	toxin secretion phage lysis holin
MM522_10600	COG3778	Protein conserved in bacteria
MM522_10605	COG3299	homolog of phage Mu protein gp47
MM522_10610	COG3628	GPW Gp25 family protein
MM522_10620	COG4193	domain, Protein
MM522_10625	COG1652	LysM domain
MM522_10630	COG3953	SLT domain
MM522_10630	COG5280	Phage tail tape measure protein TP901
MM522_10695	COG4653	Phage capsid family
MM522_10700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MM522_10710	COG2369	cell adhesion
MM522_10715	COG5518	Phage portal protein
MM522_10720	COG1783	phage Terminase large subunit
MM522_10725	COG5484	DNA packaging
MM522_10735	COG3677	Transposase
MM522_10750	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MM522_10760	COG1484	DNA-dependent DNA replication
MM522_10765	COG3935	DnaD domain protein
MM522_10770	COG3723	Recombinational DNA repair protein, rece pathway
MM522_10775	COG5377	YqaJ viral recombinase family
MM522_10805	COG1476	TRANSCRIPTIONal
MM522_10810	COG3620	sequence-specific DNA binding
MM522_10820	COG0563	adenylate kinase activity
MM522_10825	COG2856	Zn peptidase
MM522_10850	COG3223	Belongs to the PsiE family
MM522_10855	COG0642	Histidine kinase
MM522_10855	COG5002	protein histidine kinase activity
MM522_10860	COG0745	RESPONSE REGULATOR receiver
MM522_10865	COG2311	Membrane
MM522_10875	COG0454	-acetyltransferase
MM522_10880	COG2249	NAD(P)H dehydrogenase (quinone) activity
MM522_10890	COG0730	response to heat
MM522_10895	COG0425	Belongs to the sulfur carrier protein TusA family
MM522_10910	COG0425	Belongs to the sulfur carrier protein TusA family
MM522_10910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MM522_10920	COG2210	Belongs to the sulfur carrier protein TusA family
MM522_10925	COG1937	Protein conserved in bacteria
MM522_10935	COG0662	Cupin 2, conserved barrel domain protein
MM522_10950	COG0789	Transcriptional regulator
MM522_10950	COG4978	Transcriptional regulator
MM522_10955	COG2814	Major facilitator Superfamily
MM522_10960	COG0456	acetyltransferase
MM522_10965	COG1253	flavin adenine dinucleotide binding
MM522_10975	COG0697	spore germination
MM522_10980	COG0583	DNA-binding transcription factor activity
MM522_10985	COG2072	flavoprotein involved in K transport
MM522_10990	COG1230	cation diffusion facilitator family transporter
MM522_10995	COG1942	4-Oxalocrotonate Tautomerase
MM522_11000	COG0583	DNA-binding transcription factor activity
MM522_11010	COG1114	Component of the transport system for branched-chain amino acids
MM522_11015	COG1687	branched-chain amino acid
MM522_11020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MM522_11025	COG1522	sequence-specific DNA binding
MM522_11035	COG2124	cytochrome p450
MM522_11045	COG1335	isochorismatase
MM522_11060	COG2318	DinB family
MM522_11070	COG2070	2-Nitropropane dioxygenase
MM522_11095	COG3443	Belongs to the bacterial solute-binding protein 9 family
MM522_11100	COG1595	DNA-templated transcription, initiation
MM522_11105	COG0667	Aldo Keto reductase
MM522_11110	COG2851	Citrate transporter
MM522_11115	COG0583	DNA-binding transcription factor activity
MM522_11120	COG2828	Protein conserved in bacteria
MM522_11125	COG3409	Peptidoglycan-binding domain 1 protein
MM522_11130	COG5566	PFAM Mor transcription activator
MM522_11135	COG0596	Alpha beta hydrolase
MM522_11140	COG4991	sh3 domain protein
MM522_11145	COG4991	sh3 domain protein
MM522_11155	COG0346	lactoylglutathione lyase activity
MM522_11165	COG5577	PFAM Coat F domain
MM522_11170	COG1063	alcohol dehydrogenase
MM522_11180	COG5577	PFAM Coat F domain
MM522_11185	COG0789	Transcriptional regulator
MM522_11195	COG1064	alcohol dehydrogenase
MM522_11200	COG0693	protein deglycase activity
MM522_11205	COG1621	beta-fructofuranosidase activity
MM522_11215	COG3716	PTS system mannose fructose sorbose family IID component
MM522_11220	COG3715	PTS system
MM522_11225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM522_11230	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM522_11235	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MM522_11235	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MM522_11245	COG1113	amino acid transport
MM522_11250	COG1280	lysine exporter protein (LysE YggA)
MM522_11255	COG1378	Sugar-specific transcriptional regulator TrmB
MM522_11260	COG1595	DNA-templated transcription, initiation
MM522_11280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MM522_11280	COG2124	cytochrome p450
MM522_11285	COG1309	transcriptional regulator
MM522_11290	COG2226	methyltransferase
MM522_11305	COG2116	formate transmembrane transporter activity
MM522_11310	COG5609	conserved protein (DUF2294)
MM522_11315	COG3383	formate dehydrogenase (NAD+) activity
MM522_11320	COG2427	Protein of unknown function (DUF1641)
MM522_11330	COG0626	cystathionine gamma-synthase activity
MM522_11335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MM522_11340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MM522_11345	COG2226	methyltransferase
MM522_11360	COG0768	penicillin binding
MM522_11365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MM522_11370	COG0572	uridine kinase
MM522_11375	COG0826	peptidase U32
MM522_11380	COG0826	peptidase U32
MM522_11385	COG4122	O-methyltransferase activity
MM522_11390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MM522_11395	COG3906	Belongs to the UPF0473 family
MM522_11400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MM522_11405	COG4472	Bacterial protein of unknown function (DUF965)
MM522_11410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MM522_11415	COG0628	permease
MM522_11420	COG1126	abc transporter atp-binding protein
MM522_11425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM522_11430	COG0765	amino acid transport
MM522_11435	COG0765	amino acid transport
MM522_11450	COG3881	PFAM PRC-barrel domain
MM522_11455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MM522_11460	COG0457	Tetratricopeptide repeat
MM522_11465	COG0482	sulfurtransferase activity
MM522_11470	COG1104	cysteine desulfurase activity
MM522_11475	COG1959	2 iron, 2 sulfur cluster binding
MM522_11480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MM522_11485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MM522_11495	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MM522_11500	COG0124	histidyl-tRNA synthetase
MM522_11510	COG3103	Sh3 type 3 domain protein
MM522_11510	COG4991	sh3 domain protein
MM522_11510	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM522_11515	COG1490	D-aminoacyl-tRNA deacylase activity
MM522_11520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MM522_11525	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MM522_11530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MM522_11530	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MM522_11535	COG5416	Lipopolysaccharide assembly protein A domain
MM522_11540	COG0490	domain, Protein
MM522_11545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MM522_11545	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MM522_11555	COG2244	polysaccharide biosynthetic process
MM522_11560	COG2323	membrane
MM522_11570	COG1862	Preprotein translocase
MM522_11575	COG0343	queuine tRNA-ribosyltransferase activity
MM522_11580	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MM522_11590	COG2255	four-way junction helicase activity
MM522_11595	COG0632	four-way junction helicase activity
MM522_11605	COG2814	Major facilitator Superfamily
MM522_11610	COG0673	inositol 2-dehydrogenase activity
MM522_11615	COG2112	serine threonine protein kinase
MM522_11640	COG1115	amino acid carrier protein
MM522_11645	COG0217	transcriptional regulatory protein
MM522_11655	COG1388	LysM domain
MM522_11660	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MM522_11665	COG0157	Belongs to the NadC ModD family
MM522_11670	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MM522_11675	COG1104	cysteine desulfurase activity
MM522_11680	COG1827	regulation of RNA biosynthetic process
MM522_11685	COG0077	Prephenate dehydratase
MM522_11690	COG4492	Belongs to the UPF0735 family
MM522_11695	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MM522_11700	COG3290	protein histidine kinase activity
MM522_11710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MM522_11715	COG2868	ribosomal protein
MM522_11720	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MM522_11725	COG1994	Peptidase M50
MM522_11730	COG0739	heme binding
MM522_11735	COG2894	cell division
MM522_11740	COG0850	regulation of cytokinetic process
MM522_11745	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MM522_11755	COG1077	Cell shape determining protein MreB Mrl
MM522_11760	COG2003	Belongs to the UPF0758 family
MM522_11765	COG0424	maF-like protein
MM522_11775	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MM522_11780	COG0285	dihydrofolate synthase activity
MM522_11785	COG0525	valine-tRNA ligase activity
MM522_11795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MM522_11800	COG1388	LysM domain
MM522_11805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MM522_11810	COG0113	porphobilinogen synthase activity
MM522_11815	COG1587	Uroporphyrinogen-III synthase
MM522_11820	COG0181	hydroxymethylbilane synthase activity
MM522_11825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MM522_11830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MM522_11840	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MM522_11845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MM522_11850	COG0470	DNA polymerase III
MM522_11850	COG1067	ATP-dependent peptidase activity
MM522_11855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MM522_11860	COG0544	peptidyl-prolyl cis-trans isomerase activity
MM522_11865	COG1477	protein flavinylation
MM522_11865	COG0457	Tetratricopeptide repeat
MM522_11870	COG0066	3-isopropylmalate dehydratase activity
MM522_11875	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MM522_11880	COG0473	3-isopropylmalate dehydrogenase activity
MM522_11885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MM522_11890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MM522_11895	COG0440	acetolactate synthase activity
MM522_11900	COG0028	Belongs to the TPP enzyme family
MM522_11910	COG0454	-acetyltransferase
MM522_11920	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
MM522_11930	COG0622	Phosphoesterase
MM522_11935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MM522_11940	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MM522_11945	COG5401	PFAM Sporulation and spore germination
MM522_11950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MM522_11955	COG1846	Transcriptional regulator
MM522_11960	COG2197	response regulator
MM522_11965	COG0824	Thioesterase
MM522_11970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MM522_11975	COG1053	succinate dehydrogenase
MM522_11980	COG2009	succinate dehydrogenase
MM522_11985	COG1719	4-vinyl reductase, 4VR
MM522_11990	COG0527	aspartate kinase activity
MM522_11995	COG0322	excinuclease ABC activity
MM522_12000	COG3118	belongs to the thioredoxin family
MM522_12005	COG3534	alpha-L-arabinofuranosidase
MM522_12010	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MM522_12015	COG2086	electron transfer activity
MM522_12020	COG1024	Enoyl-CoA hydratase
MM522_12025	COG1309	transcriptional regulator
MM522_12030	COG0318	PFAM AMP-dependent synthetase and ligase
MM522_12035	COG3766	membrane
MM522_12040	COG1193	negative regulation of DNA recombination
MM522_12045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MM522_12045	COG1796	DNA polymerase
MM522_12050	COG1286	toxin biosynthetic process
MM522_12055	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MM522_12060	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MM522_12065	COG0072	phenylalanine-tRNA ligase activity
MM522_12065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM522_12070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MM522_12080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MM522_12090	COG3835	regulator
MM522_12095	COG0277	FAD linked oxidase domain protein
MM522_12100	COG0247	lactate metabolic process
MM522_12105	COG0346	lactoylglutathione lyase activity
MM522_12115	COG1966	Carbon starvation protein
MM522_12120	COG3534	alpha-L-arabinofuranosidase
MM522_12125	COG0395	ABC-type sugar transport system, permease component
MM522_12130	COG1175	transmembrane transport
MM522_12135	COG1653	transport
MM522_12140	COG0371	Dehydrogenase
MM522_12145	COG0647	UMP catabolic process
MM522_12150	COG0235	Class ii aldolase
MM522_12155	COG1069	ribulokinase activity
MM522_12160	COG2160	L-arabinose isomerase activity
MM522_12165	COG3507	Belongs to the glycosyl hydrolase 43 family
MM522_12170	COG1363	Peptidase, m42
MM522_12180	COG3326	Membrane
MM522_12185	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MM522_12190	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MM522_12195	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MM522_12205	COG1346	cytolysis
MM522_12210	COG1380	Effector of murein hydrolase LrgA
MM522_12215	COG3279	Response regulator of the LytR AlgR family
MM522_12220	COG3275	phosphorelay sensor kinase activity
MM522_12225	COG1011	Hydrolase
MM522_12230	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MM522_12240	COG0398	Pfam SNARE associated Golgi protein
MM522_12245	COG1484	DNA-dependent DNA replication
MM522_12250	COG3611	Membrane attachment protein
MM522_12255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MM522_12260	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MM522_12265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MM522_12270	COG1733	regulation of RNA biosynthetic process
MM522_12275	COG2814	Major facilitator Superfamily
MM522_12280	COG0656	L-ascorbic acid biosynthetic process
MM522_12285	COG0237	dephospho-CoA kinase activity
MM522_12290	COG1971	Probably functions as a manganese efflux pump
MM522_12295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MM522_12300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MM522_12300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MM522_12305	COG5002	protein histidine kinase activity
MM522_12310	COG0745	RESPONSE REGULATOR receiver
MM522_12315	COG0039	L-malate dehydrogenase activity
MM522_12320	COG0538	isocitrate dehydrogenase activity
MM522_12325	COG0372	Belongs to the citrate synthase family
MM522_12330	COG2707	UPF0756 membrane protein
MM522_12335	COG0628	permease
MM522_12340	COG3030	protein affecting phage T7 exclusion by the F plasmid
MM522_12345	COG0469	pyruvate kinase activity
MM522_12350	COG0205	6-phosphofructokinase activity
MM522_12355	COG0825	malonyl-CoA metabolic process
MM522_12360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MM522_12365	COG0281	malic enzyme
MM522_12370	COG0587	DNA-directed DNA polymerase activity
MM522_12390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MM522_12400	COG4109	DRTGG domain
MM522_12405	COG0730	response to heat
MM522_12410	COG1473	amidohydrolase
MM522_12415	COG0196	riboflavin kinase activity
MM522_12420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM522_12425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MM522_12430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM522_12435	COG1126	abc transporter atp-binding protein
MM522_12440	COG0765	amino acid transport
MM522_12445	COG0765	amino acid transport
MM522_12450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM522_12455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM522_12460	COG0454	-acetyltransferase
MM522_12465	COG0583	DNA-binding transcription factor activity
MM522_12470	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MM522_12475	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_12480	COG0165	Argininosuccinate lyase
MM522_12485	COG0137	argininosuccinate synthase activity
MM522_12490	COG0521	Mo-molybdopterin cofactor biosynthetic process
MM522_12495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MM522_12505	COG0827	DNA restriction-modification system
MM522_12510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MM522_12515	COG3874	Sporulation protein YtfJ
MM522_12525	COG1714	RDD family
MM522_12530	COG0616	signal peptide processing
MM522_12535	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MM522_12540	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MM522_12545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MM522_12555	COG0301	tRNA thio-modification
MM522_12560	COG1104	cysteine desulfurase activity
MM522_12565	COG1114	Component of the transport system for branched-chain amino acids
MM522_12570	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MM522_12575	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MM522_12580	COG1309	transcriptional regulator
MM522_12585	COG1956	GAF domain-containing protein
MM522_12590	COG2203	Gaf domain
MM522_12590	COG2199	diguanylate cyclase activity
MM522_12595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MM522_12600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MM522_12605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MM522_12610	COG0454	-acetyltransferase
MM522_12615	COG0517	IMP dehydrogenase activity
MM522_12620	COG0123	including yeast histone deacetylase and acetoin utilization protein
MM522_12625	COG1360	Flagellar Motor Protein
MM522_12630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MM522_12635	COG1609	Transcriptional regulator
MM522_12640	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MM522_12640	COG1605	Chorismate mutase
MM522_12645	COG3118	belongs to the thioredoxin family
MM522_12650	COG4980	gas vesicle protein
MM522_12655	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MM522_12660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MM522_12665	COG1674	ftsk spoiiie
MM522_12670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM522_12675	COG4848	Belongs to the UPF0354 family
MM522_12680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM522_12695	COG1363	Peptidase, m42
MM522_12700	COG5584	Small secreted protein
MM522_12705	COG0281	malic enzyme
MM522_12710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM522_12715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MM522_12725	COG0510	thiamine kinase activity
MM522_12735	COG1597	lipid kinase activity
MM522_12745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MM522_12750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MM522_12755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MM522_12760	COG2252	PERMEase
MM522_12765	COG4473	ABC transporter
MM522_12770	COG1131	(ABC) transporter
MM522_12775	COG1349	DNA-binding transcription factor activity
MM522_12780	COG1187	pseudouridine synthase activity
MM522_12785	COG2244	polysaccharide biosynthetic process
MM522_12790	COG2081	HI0933 family
MM522_12795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MM522_12805	COG5578	integral membrane protein
MM522_12810	COG0673	inositol 2-dehydrogenase activity
MM522_12815	COG1653	transport
MM522_12820	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MM522_12825	COG4209	transmembrane transport
MM522_12830	COG2207	Transcriptional regulator
MM522_12835	COG1653	transport
MM522_12840	COG0395	ABC-type sugar transport system, permease component
MM522_12845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MM522_12850	COG2124	cytochrome p450
MM522_12855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MM522_12865	COG0156	8-amino-7-oxononanoate synthase activity
MM522_12870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MM522_12880	COG1073	alpha beta
MM522_12885	COG1609	Transcriptional regulator
MM522_12890	COG1653	transport
MM522_12895	COG1175	transmembrane transport
MM522_12900	COG0395	ABC-type sugar transport system, permease component
MM522_12905	COG1486	melibiose metabolic process
MM522_12910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MM522_12915	COG0495	leucyl-tRNA aminoacylation
MM522_12925	COG2202	Pas domain
MM522_12925	COG1366	Belongs to the anti-sigma-factor antagonist family
MM522_12930	COG2814	Major facilitator Superfamily
MM522_12935	COG2433	Pfam Transposase IS66
MM522_12940	COG0577	efflux transmembrane transporter activity
MM522_12945	COG1136	(ABC) transporter
MM522_12950	COG2205	protein histidine kinase activity
MM522_12955	COG0745	RESPONSE REGULATOR receiver
MM522_12960	COG0577	efflux transmembrane transporter activity
MM522_12965	COG1136	(ABC) transporter
MM522_12980	COG1131	(ABC) transporter
MM522_12985	COG1725	Transcriptional regulator
MM522_13000	COG1242	4 iron, 4 sulfur cluster binding
MM522_13005	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MM522_13015	COG2267	carboxylic ester hydrolase activity
MM522_13025	COG1113	amino acid transport
MM522_13030	COG0367	asparagine synthase
MM522_13035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MM522_13040	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MM522_13050	COG1506	peptidase
MM522_13055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MM522_13060	COG1116	anion transmembrane transporter activity
MM522_13065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MM522_13070	COG0494	nUDIX hydrolase
MM522_13075	COG4824	toxin secretion phage lysis holin
MM522_13080	COG0783	Belongs to the Dps family
MM522_13095	COG1854	S-ribosylhomocysteine lyase activity
MM522_13100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MM522_13105	COG0288	reversible hydration of carbon dioxide
MM522_13110	COG0254	rRNA binding
MM522_13115	COG1271	oxidase subunit
MM522_13120	COG1294	oxidase, subunit
MM522_13130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MM522_13135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MM522_13135	COG1321	iron dependent repressor
MM522_13140	COG1121	(ABC) transporter
MM522_13145	COG0803	Belongs to the bacterial solute-binding protein 9 family
MM522_13150	COG4948	Mandelate Racemase Muconate Lactonizing
MM522_13155	COG0318	PFAM AMP-dependent synthetase and ligase
MM522_13160	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MM522_13165	COG0596	Alpha beta hydrolase
MM522_13170	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MM522_13175	COG1169	isochorismate synthase
MM522_13180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MM522_13185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MM522_13190	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MM522_13195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MM522_13200	COG0438	transferase activity, transferring glycosyl groups
MM522_13210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MM522_13215	COG0438	transferase activity, transferring glycosyl groups
MM522_13220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MM522_13225	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MM522_13230	COG0058	SHG alpha-glucan phosphorylase activity
MM522_13235	COG0297	glycogen (starch) synthase activity
MM522_13240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MM522_13245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MM522_13250	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MM522_13375	COG3859	Proton-coupled thiamine transporter YuaJ
MM522_13380	COG1247	-acetyltransferase
MM522_13385	COG2268	Band 7 protein
MM522_13390	COG1585	Membrane protein implicated in regulation of membrane protease activity
MM522_13395	COG2318	DinB family
MM522_13405	COG1454	alcohol dehydrogenase
MM522_13410	COG1012	belongs to the aldehyde dehydrogenase family
MM522_13415	COG1510	regulation of RNA biosynthetic process
MM522_13425	COG0569	domain protein
MM522_13430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MM522_13435	COG4682	membrane
MM522_13440	COG1705	Flagellar rod assembly protein muramidase FlgJ
MM522_13445	COG0477	Major facilitator Superfamily
MM522_13450	COG5553	Cysteine dioxygenase type I
MM522_13460	COG1968	undecaprenyl-diphosphatase activity
MM522_13465	COG0628	permease
MM522_13470	COG0673	inositol 2-dehydrogenase activity
MM522_13475	COG4806	L-rhamnose isomerase
MM522_13480	COG3254	rhamnose metabolic process
MM522_13485	COG1070	Carbohydrate kinase
MM522_13490	COG1349	DNA-binding transcription factor activity
MM522_13495	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_13495	COG3347	Dehydrogenase
MM522_13500	COG0840	transmembrane signaling receptor activity
MM522_13505	COG0840	transmembrane signaling receptor activity
MM522_13510	COG0840	transmembrane signaling receptor activity
MM522_13515	COG0840	transmembrane signaling receptor activity
MM522_13530	COG0432	Pfam Uncharacterised protein family UPF0047
MM522_13540	COG0366	Alpha amylase catalytic
MM522_13545	COG1253	flavin adenine dinucleotide binding
MM522_13550	COG2738	Putative neutral zinc metallopeptidase
MM522_13565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MM522_13580	COG0166	Belongs to the GPI family
MM522_13585	COG1979	alcohol dehydrogenase
MM522_13590	COG1979	alcohol dehydrogenase
MM522_13595	COG2155	Conserved Protein
MM522_13600	COG1098	S1 RNA binding domain
MM522_13605	COG0436	Aminotransferase
MM522_13610	COG1522	sequence-specific DNA binding
MM522_13615	COG2267	carboxylic ester hydrolase activity
MM522_13625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MM522_13630	COG2205	protein histidine kinase activity
MM522_13640	COG5018	Exonuclease
MM522_13650	COG2814	Major facilitator Superfamily
MM522_13655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM522_13660	COG3011	Protein conserved in bacteria
MM522_13670	COG3290	protein histidine kinase activity
MM522_13675	COG4565	transcriptional regulatory protein
MM522_13680	COG1744	ABC transporter substrate-binding protein PnrA-like
MM522_13685	COG3845	ABC transporter
MM522_13690	COG4603	Belongs to the binding-protein-dependent transport system permease family
MM522_13695	COG1079	Belongs to the binding-protein-dependent transport system permease family
MM522_13700	COG3493	citrate carrier protein
MM522_13710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MM522_13710	COG2111	Na H antiporter
MM522_13715	COG2111	Na H antiporter
MM522_13720	COG1006	Multisubunit Na H antiporter MnhC subunit
MM522_13725	COG0651	ATP synthesis coupled electron transport
MM522_13730	COG1863	multisubunit Na H antiporter MnhE subunit
MM522_13735	COG2212	antiporter activity
MM522_13740	COG1320	monovalent cation:proton antiporter activity
MM522_13745	COG2050	protein possibly involved in aromatic compounds catabolism
MM522_13750	COG2197	response regulator
MM522_13755	COG4585	Histidine kinase
MM522_13765	COG0142	geranyltranstransferase activity
MM522_13785	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MM522_13790	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MM522_13795	COG1335	isochorismatase
MM522_13800	COG5506	Protein of unknown function (DUF1694)
MM522_13815	COG0628	permease
MM522_13830	COG1418	mRNA catabolic process
MM522_13835	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_13845	COG1511	domain protein
MM522_13850	COG0433	COG0433 Predicted ATPase
MM522_13850	COG1674	ftsk spoiiie
MM522_13855	COG4499	WXG100 protein secretion system (Wss), protein YukC
MM522_13860	COG5417	Belongs to the EsaB family
MM522_13865	COG4842	Belongs to the WXG100 family
MM522_13870	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MM522_13870	COG2508	Transcriptional regulator
MM522_13875	COG0686	Belongs to the AlaDH PNT family
MM522_13880	COG5634	Uncharacterized conserved protein (DUF2278)
MM522_13885	COG3251	PFAM MbtH domain protein
MM522_13890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_13900	COG3433	isochorismatase activity
MM522_13900	COG1535	isochorismatase
MM522_13905	COG1021	2,3-dihydroxybenzoate-AMP ligase
MM522_13910	COG1169	isochorismate synthase
MM522_13915	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_13920	COG2819	hydrolase of the alpha beta superfamily
MM522_13925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MM522_13930	COG1268	BioY protein
MM522_13940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MM522_13945	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MM522_13950	COG3584	3D domain protein
MM522_13965	COG1252	NADH dehydrogenase
MM522_13970	COG0492	ferredoxin-NADP+ reductase activity
MM522_13980	COG0516	GMP reductase activity
MM522_13985	COG2808	Putative FMN-binding domain
MM522_13990	COG0456	acetyltransferase
MM522_13995	COG0316	Belongs to the HesB IscA family
MM522_14000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MM522_14005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MM522_14010	COG4844	belongs to the
MM522_14015	COG1252	NADH dehydrogenase
MM522_14020	COG4837	Protein of unknown function (DUF1462)
MM522_14025	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MM522_14030	COG0823	Involved in the tonB-independent uptake of proteins
MM522_14030	COG4946	Tricorn protease homolog
MM522_14030	COG1506	peptidase
MM522_14035	COG0083	homoserine kinase activity
MM522_14040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MM522_14045	COG0460	homoserine dehydrogenase
MM522_14050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MM522_14055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MM522_14060	COG0647	UMP catabolic process
MM522_14065	COG2445	Protein of unknown function DUF86
MM522_14070	COG4470	Protein conserved in bacteria
MM522_14080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MM522_14085	COG0739	heme binding
MM522_14095	COG3377	Domain of unknown function (DUF1805)
MM522_14100	COG0737	Belongs to the 5'-nucleotidase family
MM522_14105	COG0730	response to heat
MM522_14110	COG1801	Protein of unknown function DUF72
MM522_14120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MM522_14125	COG2508	Transcriptional regulator
MM522_14130	COG2233	PERMEase
MM522_14135	COG2233	PERMEase
MM522_14140	COG3648	Uricase
MM522_14140	COG3195	allantoin biosynthetic process
MM522_14145	COG2351	hydroxyisourate hydrolase activity
MM522_14155	COG2080	2 iron, 2 sulfur cluster binding
MM522_14160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MM522_14165	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MM522_14170	COG2068	MobA-Related Protein
MM522_14175	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MM522_14180	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MM522_14185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MM522_14195	COG2356	endonuclease I
MM522_14200	COG3842	ATPase activity
MM522_14205	COG2188	Transcriptional regulator
MM522_14210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM522_14215	COG0395	ABC-type sugar transport system, permease component
MM522_14220	COG1175	transmembrane transport
MM522_14225	COG1653	transport
MM522_14230	COG2222	sugar isomerase
MM522_14235	COG0322	excinuclease ABC activity
MM522_14240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MM522_14255	COG0719	Fe-S assembly protein
MM522_14260	COG0822	iron-sulfur transferase activity
MM522_14265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MM522_14270	COG0719	Fe-S assembly protein
MM522_14275	COG0396	ATPase activity
MM522_14285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MM522_14290	COG1464	Belongs to the NlpA lipoprotein family
MM522_14295	COG2011	ABC-type metal ion transport system permease component
MM522_14300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MM522_14310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM522_14315	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MM522_14325	COG0509	glycine decarboxylation via glycine cleavage system
MM522_14330	COG1393	Belongs to the ArsC family
MM522_14335	COG1960	acyl-CoA dehydrogenase activity
MM522_14340	COG0183	Belongs to the thiolase family
MM522_14345	COG1024	Enoyl-CoA hydratase
MM522_14345	COG1250	3-hydroxyacyl-CoA dehydrogenase
MM522_14355	COG0506	proline dehydrogenase activity
MM522_14365	COG5577	PFAM Coat F domain
MM522_14370	COG1846	Transcriptional regulator
MM522_14375	COG0477	Major facilitator Superfamily
MM522_14380	COG1942	4-Oxalocrotonate Tautomerase
MM522_14385	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_14390	COG0583	DNA-binding transcription factor activity
MM522_14400	COG1120	ATPase activity
MM522_14415	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_14420	COG0783	Belongs to the Dps family
MM522_14425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM522_14430	COG0745	RESPONSE REGULATOR receiver
MM522_14435	COG2770	Histidine kinase
MM522_14435	COG2205	protein histidine kinase activity
MM522_14445	COG1309	transcriptional regulator
MM522_14450	COG0114	fumarate hydratase activity
MM522_14460	COG0697	spore germination
MM522_14465	COG0814	amino acid
MM522_14475	COG2197	response regulator
MM522_14480	COG4585	Histidine kinase
MM522_14485	COG4758	membrane
MM522_14490	COG3595	metallopeptidase activity
MM522_14495	COG1842	Phage shock protein A
MM522_14500	COG4758	membrane
MM522_14505	COG2814	Major facilitator Superfamily
MM522_14510	COG2096	Adenosyltransferase
MM522_14515	COG1120	ATPase activity
MM522_14520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM522_14525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MM522_14530	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_14535	COG3386	PFAM SMP-30 Gluconolaconase
MM522_14540	COG2205	protein histidine kinase activity
MM522_14545	COG0745	RESPONSE REGULATOR receiver
MM522_14555	COG1191	sigma factor activity
MM522_14565	COG2140	Oxalate decarboxylase
MM522_14575	COG0577	efflux transmembrane transporter activity
MM522_14580	COG1136	(ABC) transporter
MM522_14585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MM522_14590	COG1120	ATPase activity
MM522_14595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM522_14600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM522_14605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MM522_14610	COG0531	amino acid
MM522_14620	COG1988	membrane-bound metal-dependent
MM522_14625	COG1368	sulfuric ester hydrolase activity
MM522_14630	COG1910	domain protein
MM522_14635	COG0725	ABC transporter, periplasmic molybdate-binding protein
MM522_14640	COG4149	molybdate abc transporter
MM522_14645	COG0656	L-ascorbic acid biosynthetic process
MM522_14655	COG0025	NhaP-type Na H and K H
MM522_14660	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MM522_14665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MM522_14670	COG3973	AAA domain
MM522_14675	COG2860	membrane
MM522_14680	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MM522_14685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MM522_14690	COG2217	Heavy metal translocating P-type atpase
MM522_14695	COG2217	Heavy metal translocating P-type atpase
MM522_14700	COG2608	mercury ion transmembrane transporter activity
MM522_14705	COG1937	Protein conserved in bacteria
MM522_14710	COG0673	inositol 2-dehydrogenase activity
MM522_14715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MM522_14720	COG1289	transmembrane transporter activity
MM522_14730	COG2076	Multidrug Resistance protein
MM522_14735	COG1309	transcriptional regulator
MM522_14740	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_14750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MM522_14755	COG0557	exoribonuclease II activity
MM522_14760	COG1647	Serine aminopeptidase, S33
MM522_14765	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MM522_14770	COG0596	Alpha beta hydrolase
MM522_14775	COG1476	TRANSCRIPTIONal
MM522_14780	COG1396	sequence-specific DNA binding
MM522_14785	COG1396	sequence-specific DNA binding
MM522_14790	COG1733	regulation of RNA biosynthetic process
MM522_14795	COG0840	transmembrane signaling receptor activity
MM522_14800	COG1174	glycine betaine transport
MM522_14805	COG1732	Glycine betaine
MM522_14810	COG1174	glycine betaine transport
MM522_14815	COG1125	glycine betaine transport
MM522_14815	COG0517	IMP dehydrogenase activity
MM522_14820	COG1510	regulation of RNA biosynthetic process
MM522_14825	COG1174	glycine betaine transport
MM522_14830	COG1732	Glycine betaine
MM522_14835	COG1174	glycine betaine transport
MM522_14840	COG1125	glycine betaine transport
MM522_14840	COG0517	IMP dehydrogenase activity
MM522_14845	COG1510	regulation of RNA biosynthetic process
MM522_14850	COG2095	MarC family integral membrane protein
MM522_14860	COG3064	Membrane
MM522_14865	COG4640	response to antibiotic
MM522_14870	COG0456	acetyltransferase
MM522_14875	COG0148	phosphopyruvate hydratase activity
MM522_14880	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MM522_14885	COG0149	triose-phosphate isomerase activity
MM522_14890	COG0126	phosphoglycerate kinase activity
MM522_14895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MM522_14900	COG2390	Transcriptional regulator
MM522_14905	COG2814	Major facilitator Superfamily
MM522_14910	COG1609	Transcriptional regulator
MM522_14915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM522_14925	COG0583	DNA-binding transcription factor activity
MM522_14930	COG0697	spore germination
MM522_14935	COG1113	amino acid transport
MM522_14940	COG3858	chitin binding
MM522_14945	COG1556	Lactate utilization protein
MM522_14950	COG1139	Iron-sulfur cluster binding protein
MM522_14955	COG0247	lactate metabolic process
MM522_14960	COG2197	response regulator
MM522_14965	COG4585	Histidine kinase
MM522_14970	COG0842	Transport permease protein
MM522_14975	COG1131	(ABC) transporter
MM522_14980	COG0596	Alpha beta hydrolase
MM522_14985	COG2208	phosphoserine phosphatase activity
MM522_14990	COG3867	Arabinogalactan endo-beta-1,4-galactanase
MM522_14995	COG1874	Beta-galactosidase
MM522_15000	COG3833	ABC-type maltose transport systems, permease component
MM522_15005	COG1175	transmembrane transport
MM522_15010	COG2182	Extracellular solute-binding protein
MM522_15015	COG1609	Transcriptional regulator
MM522_15020	COG2186	Transcriptional regulator
MM522_15025	COG1620	l-lactate permease
MM522_15030	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MM522_15040	COG5039	Polysaccharide pyruvyl transferase
MM522_15045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MM522_15050	COG0110	maltose O-acetyltransferase activity
MM522_15055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MM522_15060	COG2244	polysaccharide biosynthetic process
MM522_15065	COG1216	Glycosyl transferase, family 2
MM522_15070	COG5039	Polysaccharide pyruvyl transferase
MM522_15075	COG1216	Glycosyl transferase, family 2
MM522_15085	COG0438	transferase activity, transferring glycosyl groups
MM522_15090	COG1215	transferase activity, transferring glycosyl groups
MM522_15095	COG0438	transferase activity, transferring glycosyl groups
MM522_15100	COG1086	Polysaccharide biosynthesis protein
MM522_15105	COG0489	protein tyrosine kinase activity
MM522_15110	COG3944	biosynthesis protein
MM522_15115	COG1396	sequence-specific DNA binding
MM522_15120	COG2272	Belongs to the type-B carboxylesterase lipase family
MM522_15130	COG3479	Phenolic acid decarboxylase
MM522_15140	COG1794	racemase activity, acting on amino acids and derivatives
MM522_15145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MM522_15150	COG1621	beta-fructofuranosidase activity
MM522_15155	COG1621	beta-fructofuranosidase activity
MM522_15160	COG0531	amino acid
MM522_15165	COG1309	transcriptional regulator
MM522_15170	COG2076	Multidrug Resistance protein
MM522_15175	COG2076	Multidrug Resistance protein
MM522_15185	COG0277	FAD linked oxidase domain protein
MM522_15190	COG3621	Patatin-like phospholipase
MM522_15200	COG0740	serine-type endopeptidase activity
MM522_15205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MM522_15210	COG0366	Alpha amylase catalytic
MM522_15215	COG1554	hydrolase, family 65, central catalytic
MM522_15220	COG5521	maltodextrose utilization protein MalA
MM522_15225	COG3833	ABC-type maltose transport systems, permease component
MM522_15230	COG1175	transmembrane transport
MM522_15235	COG2182	Extracellular solute-binding protein
MM522_15245	COG1609	Transcriptional regulator
MM522_15250	COG1611	Belongs to the LOG family
MM522_15255	COG1694	Mazg nucleotide pyrophosphohydrolase
MM522_15260	COG0659	secondary active sulfate transmembrane transporter activity
MM522_15265	COG0288	reversible hydration of carbon dioxide
MM522_15270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MM522_15275	COG0577	efflux transmembrane transporter activity
MM522_15280	COG1136	(ABC) transporter
MM522_15285	COG5002	protein histidine kinase activity
MM522_15290	COG0745	RESPONSE REGULATOR receiver
MM522_15300	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MM522_15305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM522_15310	COG1481	regulation of sporulation
MM522_15315	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MM522_15320	COG1660	Displays ATPase and GTPase activities
MM522_15325	COG1051	belongs to the nudix hydrolase family
MM522_15330	COG0492	ferredoxin-NADP+ reductase activity
MM522_15335	COG3883	PFAM NLP P60 protein
MM522_15335	COG0791	NLP P60 protein
MM522_15340	COG0457	Tetratricopeptide repeat
MM522_15345	COG1132	(ABC) transporter
MM522_15370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MM522_15370	COG0140	phosphoribosyl-ATP diphosphatase activity
MM522_15375	COG0107	imidazoleglycerol-phosphate synthase activity
MM522_15380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MM522_15385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MM522_15390	COG0131	Imidazoleglycerol-phosphate dehydratase
MM522_15395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MM522_15400	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MM522_15405	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MM522_15410	COG4990	cell redox homeostasis
MM522_15415	COG5297	Belongs to the glycosyl hydrolase family 6
MM522_15420	COG0110	maltose O-acetyltransferase activity
MM522_15425	COG0546	phosphoglycolate phosphatase activity
MM522_15430	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MM522_15435	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MM522_15440	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MM522_15445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MM522_15450	COG0363	glucosamine-6-phosphate deaminase activity
MM522_15455	COG2188	Transcriptional regulator
MM522_15460	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MM522_15465	COG1846	Transcriptional regulator
MM522_15470	COG2124	cytochrome p450
MM522_15480	COG1846	Transcriptional regulator
MM522_15485	COG2814	Major facilitator Superfamily
MM522_15490	COG1950	PFAM Membrane protein of
MM522_15495	COG1983	PspC domain protein
MM522_15500	COG3595	metallopeptidase activity
MM522_15515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MM522_15520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MM522_15530	COG4897	Protein conserved in bacteria
MM522_15535	COG0574	Belongs to the PEP-utilizing enzyme family
MM522_15535	COG3848	Pyruvate phosphate dikinase
MM522_15540	COG1309	transcriptional regulator
MM522_15545	COG2814	Major facilitator Superfamily
MM522_15550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM522_15560	COG0793	Belongs to the peptidase S41A family
MM522_15560	COG3409	Peptidoglycan-binding domain 1 protein
MM522_15565	COG2177	Part of the ABC transporter FtsEX involved in
MM522_15570	COG2884	Cell division ATP-binding protein ftsE
MM522_15575	COG2010	Cytochrome c
MM522_15580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM522_15590	COG0653	protein targeting
MM522_15595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MM522_15610	COG1516	flagellar protein fliS
MM522_15615	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MM522_15620	COG1334	flagellar protein FlaG
MM522_15625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MM522_15630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MM522_15635	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MM522_15645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MM522_15650	COG1256	bacterial-type flagellum assembly
MM522_15650	COG4786	Flagellar basal body rod
MM522_15655	COG3418	PFAM FlgN family protein
MM522_15660	COG2747	anti-sigma28 factor FlgM
MM522_15670	COG1040	competence protein
MM522_15680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MM522_15685	COG1307	EDD domain protein, DegV family
MM522_15690	COG2197	response regulator
MM522_15695	COG4585	Histidine kinase
MM522_15700	COG1739	Uncharacterized protein family UPF0029
MM522_15705	COG1316	TRANSCRIPTIONal
MM522_15710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MM522_15715	COG0438	transferase activity, transferring glycosyl groups
MM522_15720	COG1215	transferase activity, transferring glycosyl groups
MM522_15725	COG3206	protein involved in exopolysaccharide biosynthesis
MM522_15730	COG3307	-O-antigen
MM522_15735	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MM522_15740	COG0438	transferase activity, transferring glycosyl groups
MM522_15740	COG0297	glycogen (starch) synthase activity
MM522_15745	COG2244	polysaccharide biosynthetic process
MM522_15760	COG2247	cell wall binding repeat
MM522_15760	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM522_15765	COG2247	cell wall binding repeat
MM522_15765	COG2385	sporulation resulting in formation of a cellular spore
MM522_15775	COG1316	TRANSCRIPTIONal
MM522_15780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MM522_15800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MM522_15805	COG1134	teichoic acid transport
MM522_15810	COG1682	transport, permease protein
MM522_15830	COG0463	Glycosyl transferase, family 2
MM522_15875	COG4193	domain, Protein
MM522_15880	COG1482	cell wall glycoprotein biosynthetic process
MM522_15885	COG0697	spore germination
MM522_15890	COG0814	amino acid
MM522_15900	COG2814	Major facilitator Superfamily
MM522_15905	COG1316	TRANSCRIPTIONal
MM522_15910	COG0561	phosphatase activity
MM522_15915	COG0791	NLP P60 protein
MM522_15925	COG2843	Capsule synthesis protein
MM522_15935	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MM522_15940	COG1609	Transcriptional regulator
MM522_15945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM522_15950	COG1869	D-ribose catabolic process
MM522_15955	COG1129	ABC transporter
MM522_15960	COG1172	Belongs to the binding-protein-dependent transport system permease family
MM522_15965	COG1879	ABC-type sugar transport system periplasmic component
MM522_15970	COG3103	Sh3 type 3 domain protein
MM522_15980	COG2249	NAD(P)H dehydrogenase (quinone) activity
MM522_15985	COG3527	Alpha-acetolactate decarboxylase
MM522_15990	COG0028	Belongs to the TPP enzyme family
MM522_15995	COG0583	DNA-binding transcription factor activity
MM522_16000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MM522_16015	COG5337	Spore coat protein CotH
MM522_16025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MM522_16035	COG0405	Gamma-glutamyltransferase
MM522_16040	COG1522	sequence-specific DNA binding
MM522_16045	COG2059	Chromate
MM522_16050	COG2059	Chromate
MM522_16060	COG0655	NAD(P)H dehydrogenase (quinone) activity
MM522_16065	COG0583	DNA-binding transcription factor activity
MM522_16080	COG5444	nuclease activity
MM522_16100	COG3878	Protein conserved in bacteria
MM522_16105	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MM522_16110	COG4464	protein tyrosine phosphatase activity
MM522_16115	COG0489	protein tyrosine kinase activity
MM522_16120	COG3944	biosynthesis protein
MM522_16130	COG4715	Zinc finger, swim domain protein
MM522_16135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MM522_16140	COG0561	phosphatase activity
MM522_16145	COG1349	DNA-binding transcription factor activity
MM522_16150	COG0629	single-stranded DNA binding
MM522_16175	COG2972	Histidine kinase
MM522_16175	COG0745	RESPONSE REGULATOR receiver
MM522_16180	COG1970	mechanosensitive ion channel activity
MM522_16185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MM522_16190	COG0457	Tetratricopeptide repeat
MM522_16195	COG4786	Flagellar basal body rod
MM522_16200	COG4786	Flagellar basal body rod
MM522_16205	COG1077	Cell shape determining protein MreB Mrl
MM522_16210	COG1609	Transcriptional regulator
MM522_16220	COG1846	Transcriptional regulator
MM522_16225	COG2814	Major facilitator Superfamily
MM522_16230	COG3420	alginic acid biosynthetic process
MM522_16235	COG1953	Uracil, thiamine, allantoin
MM522_16240	COG0477	Major facilitator Superfamily
MM522_16245	COG1335	isochorismatase
MM522_16255	COG0004	ammonium transporteR
MM522_16260	COG0347	Belongs to the P(II) protein family
MM522_16265	COG0671	phosphoesterase, PA-phosphatase related
MM522_16275	COG0739	heme binding
MM522_16280	COG1247	-acetyltransferase
MM522_16300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MM522_16305	COG0789	Transcriptional regulator
MM522_16315	COG2910	NAD(P)H-binding
MM522_16320	COG1959	2 iron, 2 sulfur cluster binding
MM522_16325	COG0804	urea catabolic process
MM522_16330	COG0832	Belongs to the urease beta subunit family
MM522_16335	COG0831	urea catabolic process
MM522_16350	COG3237	CsbD-like
MM522_16355	COG1994	Peptidase M50
MM522_16360	COG0457	Tetratricopeptide repeat
MM522_16365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MM522_16370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MM522_16380	COG2304	oxidoreductase activity
MM522_16390	COG2304	oxidoreductase activity
MM522_16395	COG2385	sporulation resulting in formation of a cellular spore
MM522_16400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MM522_16410	COG4836	Membrane
MM522_16420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MM522_16425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MM522_16430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MM522_16435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MM522_16440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MM522_16445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MM522_16455	COG0356	it plays a direct role in the translocation of protons across the membrane
MM522_16465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MM522_16470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MM522_16475	COG4475	Protein of unknown function (DUF436)
MM522_16480	COG0698	ribose 5-phosphate isomerase
MM522_16485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MM522_16490	COG1971	Probably functions as a manganese efflux pump
MM522_16495	COG0009	L-threonylcarbamoyladenylate synthase
MM522_16500	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MM522_16520	COG2890	protein-(glutamine-N5) methyltransferase activity
MM522_16525	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MM522_16530	COG0346	lactoylglutathione lyase activity
MM522_16535	COG0789	Transcriptional regulator
MM522_16540	COG0679	Auxin Efflux Carrier
MM522_16545	COG0281	malic enzyme
MM522_16550	COG1435	thymidine kinase activity
MM522_16560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MM522_16570	COG1494	fructose-1,6-bisphosphatase
MM522_16575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MM522_16580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MM522_16585	COG0191	fructose-bisphosphate aldolase activity
MM522_16590	COG2204	response regulator
MM522_16595	COG4821	SIS domain
MM522_16600	COG0504	CTP synthase activity
MM522_16605	COG3343	RNA polymerase activity
MM522_16610	COG1960	acyl-CoA dehydrogenase activity
MM522_16615	COG2181	nitrate reductase activity
MM522_16615	COG0247	lactate metabolic process
MM522_16620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MM522_16625	COG4294	response to UV
MM522_16635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MM522_16640	COG1132	(ABC) transporter
MM522_16645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MM522_16655	COG2181	nitrate reductase activity
MM522_16660	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MM522_16665	COG1140	nitrate reductase beta subunit
MM522_16670	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MM522_16675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MM522_16685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MM522_16690	COG2223	nitrite transmembrane transporter activity
MM522_16695	COG0018	arginyl-trna synthetase
MM522_16700	COG4506	Protein conserved in bacteria
MM522_16715	COG0535	radical SAM domain protein
MM522_16725	COG1131	(ABC) transporter
MM522_16730	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MM522_16735	COG0612	Peptidase, M16
MM522_16740	COG0612	Peptidase, M16
MM522_16750	COG3391	amine dehydrogenase activity
MM522_16755	COG3391	amine dehydrogenase activity
MM522_16760	COG0457	Tetratricopeptide repeat
MM522_16780	COG1131	(ABC) transporter
MM522_16790	COG0010	Belongs to the arginase family
MM522_16795	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MM522_16800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM522_16810	COG1994	Peptidase M50
MM522_16815	COG1942	4-Oxalocrotonate Tautomerase
MM522_16820	COG1846	Transcriptional regulator
MM522_16825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MM522_16835	COG0477	Major facilitator Superfamily
MM522_16840	COG1959	2 iron, 2 sulfur cluster binding
MM522_16845	COG3465	dGTPase activity
MM522_16850	COG1078	dGTPase activity
MM522_16855	COG4844	belongs to the
MM522_16865	COG0697	spore germination
MM522_16870	COG0095	Lipoate-protein ligase
MM522_16875	COG0583	DNA-binding transcription factor activity
MM522_16880	COG0280	phosphate acetyltransferase
MM522_16885	COG3253	May function as heme-dependent peroxidase
MM522_16890	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_16895	COG0436	Aminotransferase
MM522_16900	COG2814	Major facilitator Superfamily
MM522_16905	COG0151	Belongs to the GarS family
MM522_16910	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_16915	COG1917	Cupin 2, conserved barrel domain protein
MM522_16920	COG0077	Prephenate dehydratase
MM522_16925	COG2814	Major facilitator Superfamily
MM522_16930	COG0833	amino acid
MM522_16935	COG4187	Peptidase family M20/M25/M40
MM522_16940	COG1012	belongs to the aldehyde dehydrogenase family
MM522_16945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MM522_16955	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MM522_16960	COG1091	dTDP-4-dehydrorhamnose reductase activity
MM522_16965	COG1088	dTDP-glucose 4,6-dehydratase activity
MM522_16970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MM522_16975	COG3980	spore coat polysaccharide biosynthesis protein
MM522_16980	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
MM522_16985	COG2089	acid synthase
MM522_16990	COG0456	acetyltransferase
MM522_16995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MM522_17000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MM522_17005	COG0463	Glycosyl transferase, family 2
MM522_17015	COG2363	Small membrane protein
MM522_17020	COG2233	PERMEase
MM522_17030	COG1012	belongs to the aldehyde dehydrogenase family
MM522_17035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MM522_17040	COG1216	Glycosyl transferase, family 2
MM522_17055	COG1695	Transcriptional regulator
MM522_17060	COG0351	phosphomethylpyrimidine kinase
MM522_17070	COG1621	beta-fructofuranosidase activity
MM522_17075	COG1263	PTS System
MM522_17075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM522_17080	COG2116	formate transmembrane transporter activity
MM522_17085	COG3711	transcriptional antiterminator
MM522_17095	COG1404	Belongs to the peptidase S8 family
MM522_17100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM522_17105	COG0778	Nitroreductase
MM522_17110	COG0772	Belongs to the SEDS family
MM522_17120	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MM522_17125	COG1845	cytochrome c oxidase, subunit III
MM522_17130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MM522_17135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MM522_17140	COG2261	transglycosylase associated protein
MM522_17145	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MM522_17150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MM522_17155	COG2246	polysaccharide biosynthetic process
MM522_17160	COG1309	transcriptional regulator
MM522_17170	COG3162	membrane
MM522_17175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MM522_17180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MM522_17185	COG2837	iron assimilation
MM522_17190	COG2822	iron ion transport
MM522_17195	COG0672	)-iron permease
MM522_17200	COG0352	thiamine-phosphate diphosphorylase activity
MM522_17205	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MM522_17210	COG0583	DNA-binding transcription factor activity
MM522_17215	COG1380	Effector of murein hydrolase LrgA
MM522_17220	COG1346	cytolysis
MM522_17225	COG2814	Major facilitator Superfamily
MM522_17230	COG4895	conserved protein (DUF2196)
MM522_17235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MM522_17240	COG0346	lactoylglutathione lyase activity
MM522_17245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MM522_17250	COG1404	Belongs to the peptidase S8 family
MM522_17255	COG1263	PTS System
MM522_17255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM522_17260	COG3711	transcriptional antiterminator
MM522_17265	COG1442	glycosyl transferase family 8
MM522_17270	COG5522	Integral membrane protein (intg_mem_TP0381)
MM522_17275	COG1846	Transcriptional regulator
MM522_17280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MM522_17285	COG2234	aminopeptidase activity
MM522_17300	COG2814	Major facilitator Superfamily
MM522_17305	COG2357	RelA SpoT domain protein
MM522_17310	COG1575	Belongs to the MenA family. Type 1 subfamily
MM522_17325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_17330	COG1696	Membrane protein involved in D-alanine export
MM522_17335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM522_17340	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MM522_17345	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MM522_17350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MM522_17355	COG1486	melibiose metabolic process
MM522_17360	COG1447	Phosphotransferase system cellobiose-specific component IIA
MM522_17365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MM522_17370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MM522_17375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM522_17375	COG3711	transcriptional antiterminator
MM522_17385	COG2094	Belongs to the DNA glycosylase MPG family
MM522_17390	COG0753	catalase activity
MM522_17395	COG2814	Major facilitator Superfamily
MM522_17400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MM522_17405	COG1131	(ABC) transporter
MM522_17425	COG1595	DNA-templated transcription, initiation
MM522_17430	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MM522_17435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MM522_17440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MM522_17445	COG4988	ABC transporter
MM522_17450	COG1294	oxidase, subunit
MM522_17455	COG1271	oxidase subunit
MM522_17460	COG3493	citrate carrier protein
MM522_17465	COG0501	Belongs to the peptidase M48B family
MM522_17475	COG0726	polysaccharide deacetylase
MM522_17480	COG3842	ATPase activity
MM522_17485	COG2508	Transcriptional regulator
MM522_17490	COG1012	belongs to the aldehyde dehydrogenase family
MM522_17495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM522_17505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MM522_17510	COG1881	PFAM PEBP family protein
MM522_17515	COG0583	DNA-binding transcription factor activity
MM522_17525	COG4585	Histidine kinase
MM522_17530	COG2197	response regulator
MM522_17535	COG2195	Cleaves the N-terminal amino acid of tripeptides
MM522_17545	COG4894	glucomannan catabolic process
MM522_17550	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MM522_17555	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MM522_17560	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_17565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MM522_17570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MM522_17575	COG2610	gluconate transmembrane transporter activity
MM522_17580	COG0500	methyltransferase
MM522_17585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MM522_17600	COG0693	protein deglycase activity
MM522_17600	COG0753	catalase activity
MM522_17605	COG2851	Citrate transporter
MM522_17610	COG2273	Hydrolase Family 16
MM522_17615	COG3711	transcriptional antiterminator
MM522_17625	COG2270	Major facilitator Superfamily
MM522_17630	COG0513	Belongs to the DEAD box helicase family
MM522_17635	COG2755	lipolytic protein G-D-S-L family
MM522_17635	COG3401	FG-GAP repeat protein
MM522_17690	COG3209	COG3209 Rhs family protein
MM522_17695	COG0697	spore germination
MM522_17700	COG0789	Transcriptional regulator
MM522_17720	COG0589	response to stress
MM522_17725	COG2723	6-phospho-beta-galactosidase activity
MM522_17730	COG1263	PTS System
MM522_17730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM522_17730	COG2190	(PTS) system
MM522_17755	COG5444	nuclease activity
MM522_17775	COG0494	nUDIX hydrolase
MM522_17780	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MM522_17785	COG3507	Belongs to the glycosyl hydrolase 43 family
MM522_17800	COG2986	histidine ammonia-lyase
MM522_17805	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MM522_17810	COG1228	amidohydrolase
MM522_17815	COG0010	Belongs to the arginase family
MM522_17820	COG0833	amino acid
MM522_17825	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MM522_17835	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MM522_17840	COG2390	Transcriptional regulator
MM522_17850	COG3192	ethanolamine utilization protein
MM522_17855	COG2079	MmgE PrpD family protein
MM522_17860	COG1473	amidohydrolase
MM522_17865	COG1126	abc transporter atp-binding protein
MM522_17870	COG0765	amino acid transport
MM522_17875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM522_17880	COG0456	acetyltransferase
MM522_17885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM522_17895	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MM522_17900	COG0561	phosphatase activity
MM522_17930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MM522_17935	COG5294	Protein conserved in bacteria
MM522_17940	COG0577	efflux transmembrane transporter activity
MM522_17945	COG1136	(ABC) transporter
MM522_17950	COG2205	protein histidine kinase activity
MM522_17955	COG0745	RESPONSE REGULATOR receiver
MM522_17960	COG0191	fructose-bisphosphate aldolase activity
MM522_17965	COG1082	Xylose isomerase domain protein TIM barrel
MM522_17970	COG1082	Xylose isomerase domain protein TIM barrel
MM522_17975	COG0673	inositol 2-dehydrogenase activity
MM522_17980	COG2814	Major facilitator Superfamily
MM522_17985	COG1082	Xylose isomerase domain protein TIM barrel
MM522_17990	COG3962	Belongs to the TPP enzyme family
MM522_17995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM522_18005	COG1012	belongs to the aldehyde dehydrogenase family
MM522_18010	COG1349	DNA-binding transcription factor activity
MM522_18015	COG0667	Aldo Keto reductase
MM522_18030	COG2814	Major facilitator Superfamily
MM522_18035	COG0326	Molecular chaperone. Has ATPase activity
MM522_18045	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_18050	COG1309	transcriptional regulator
MM522_18055	COG1012	belongs to the aldehyde dehydrogenase family
MM522_18060	COG0456	acetyltransferase
MM522_18065	COG2850	peptidyl-arginine hydroxylation
MM522_18070	COG2226	methyltransferase
MM522_18085	COG0367	asparagine synthase
MM522_18090	COG2814	Major facilitator Superfamily
MM522_18095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MM522_18105	COG1714	RDD family
MM522_18110	COG2311	Membrane
MM522_18115	COG1917	Cupin 2, conserved barrel domain protein
MM522_18120	COG1309	transcriptional regulator
MM522_18125	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_18130	COG1846	Transcriptional regulator
MM522_18135	COG1380	Effector of murein hydrolase LrgA
MM522_18140	COG1346	cytolysis
MM522_18145	COG5039	Polysaccharide pyruvyl transferase
MM522_18150	COG1929	Belongs to the glycerate kinase type-1 family
MM522_18155	COG1802	Transcriptional regulator
MM522_18160	COG1070	Carbohydrate kinase
MM522_18165	COG2610	gluconate transmembrane transporter activity
MM522_18170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MM522_18175	COG0450	alkyl hydroperoxide reductase
MM522_18180	COG3634	alkyl hydroperoxide reductase activity
MM522_18190	COG2723	6-phospho-beta-galactosidase activity
MM522_18195	COG2190	(PTS) system
MM522_18205	COG2188	Transcriptional regulator
MM522_18215	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
MM522_18250	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MM522_18265	COG1063	alcohol dehydrogenase
MM522_18285	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MM522_18290	COG0456	acetyltransferase
MM522_18295	COG0457	Tetratricopeptide repeat
MM522_18305	COG0010	Belongs to the arginase family
MM522_18310	COG0833	amino acid
MM522_18315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MM522_18320	COG3829	transcription factor binding
MM522_18325	COG5002	protein histidine kinase activity
MM522_18330	COG0745	RESPONSE REGULATOR receiver
MM522_18350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM522_18355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MM522_18360	COG4853	Protein conserved in bacteria
MM522_18365	COG4863	YycH protein
MM522_18370	COG5002	protein histidine kinase activity
MM522_18375	COG0745	RESPONSE REGULATOR receiver
MM522_18405	COG0346	lactoylglutathione lyase activity
MM522_18410	COG0305	Participates in initiation and elongation during chromosome replication
MM522_18425	COG3093	addiction module antidote protein HigA
MM522_18430	COG2807	transmembrane transport
MM522_18435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MM522_18440	COG0359	binds to the 23S rRNA
MM522_18445	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MM522_18450	COG4241	membrane
MM522_18460	COG5577	PFAM Coat F domain
MM522_18465	COG1733	regulation of RNA biosynthetic process
MM522_18470	COG1227	inorganic diphosphatase activity
MM522_18480	COG2271	Major facilitator Superfamily
MM522_18485	COG4978	Transcriptional regulator
MM522_18485	COG0789	Transcriptional regulator
MM522_18495	COG4319	ketosteroid isomerase
MM522_18500	COG1357	PFAM Pentapeptide repeats (8 copies)
MM522_18505	COG2814	Major facilitator Superfamily
MM522_18510	COG0583	DNA-binding transcription factor activity
MM522_18515	COG2153	protein acetylation
MM522_18530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM522_18535	COG1846	Transcriptional regulator
MM522_18540	COG2153	protein acetylation
MM522_18545	COG2364	Membrane
MM522_18550	COG0456	acetyltransferase
MM522_18555	COG2315	Protein conserved in bacteria
MM522_18560	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MM522_18570	COG2814	Major facilitator Superfamily
MM522_18575	COG1331	Highly conserved protein containing a thioredoxin domain
MM522_18580	COG1266	CAAX protease self-immunity
MM522_18585	COG0477	Major facilitator Superfamily
MM522_18585	COG2814	Major facilitator Superfamily
MM522_18590	COG0110	maltose O-acetyltransferase activity
MM522_18595	COG0346	lactoylglutathione lyase activity
MM522_18600	COG1609	Transcriptional regulator
MM522_18605	COG0708	Exodeoxyribonuclease III
MM522_18610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MM522_18615	COG0629	single-stranded DNA binding
MM522_18620	COG0360	Binds together with S18 to 16S ribosomal RNA
MM522_18625	COG0012	GTP binding
MM522_18630	COG0243	molybdopterin cofactor binding
MM522_18635	COG4481	Protein conserved in bacteria
MM522_18640	COG3949	Membrane
MM522_18650	COG1475	DNA binding
MM522_18655	COG1192	Involved in chromosome partitioning
MM522_18665	COG1475	DNA binding
MM522_18670	COG0357	Ribosomal RNA small subunit methyltransferase G
MM522_18675	COG0445	tRNA wobble uridine modification
MM522_18680	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MM522_18685	COG1847	R3H domain protein
MM522_18690	COG0706	membrane insertase activity
MM522_18695	COG0594	ribonuclease P activity
MM522_18705	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MM522_18710	COG0592	DNA-directed DNA polymerase activity
MM522_18715	COG2501	S4 domain
MM522_18720	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MM522_18730	COG0187	DNA topoisomerase II activity
MM522_18735	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MM522_18770	COG0516	GMP reductase activity
MM522_18770	COG0517	IMP dehydrogenase activity
MM522_18775	COG1686	Belongs to the peptidase S11 family
MM522_18780	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MM522_18785	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MM522_18790	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MM522_18800	COG1428	Deoxynucleoside kinase
MM522_18805	COG1428	Deoxynucleoside kinase
MM522_18810	COG1388	LysM domain
MM522_18810	COG3858	chitin binding
MM522_18815	COG1335	isochorismatase
MM522_18820	COG0590	tRNA wobble adenosine to inosine editing
MM522_18830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MM522_18835	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MM522_18840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MM522_18885	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MM522_18890	COG3853	Toxic anion resistance protein (TelA)
MM522_18895	COG1982	Orn Lys Arg decarboxylase major
MM522_18900	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MM522_18905	COG3870	Protein conserved in bacteria
MM522_18910	COG1728	Protein conserved in bacteria
MM522_18915	COG0470	DNA polymerase III
MM522_18920	COG1774	PSP1 C-terminal conserved region
MM522_18925	COG4467	Involved in initiation control of chromosome replication
MM522_18930	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MM522_18935	COG2827	Endonuclease containing a URI domain
MM522_18940	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MM522_18945	COG2002	toxin-antitoxin pair type II binding
MM522_18950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM522_18950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM522_18955	COG0084	hydrolase, TatD family'
MM522_18960	COG3583	domain protein
MM522_18960	COG3584	3D domain protein
MM522_18965	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MM522_18970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MM522_18980	COG4466	Protein conserved in bacteria
MM522_18990	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MM522_18995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MM522_19000	COG0251	oxidation-reduction process
MM522_19005	COG2088	sporulation resulting in formation of a cellular spore
MM522_19010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MM522_19015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MM522_19020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MM522_19025	COG0193	aminoacyl-tRNA hydrolase activity
MM522_19035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MM522_19040	COG2002	toxin-antitoxin pair type II binding
MM522_19045	COG2244	polysaccharide biosynthetic process
MM522_19050	COG3956	TIGRFAM MazG family protein
MM522_19055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MM522_19070	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MM522_19075	COG1098	S1 RNA binding domain
MM522_19090	COG2208	phosphoserine phosphatase activity
MM522_19095	COG2304	oxidoreductase activity
MM522_19100	COG0515	serine threonine protein kinase
MM522_19105	COG0037	tRNA processing
MM522_19110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MM522_19115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM522_19120	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MM522_19125	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MM522_19130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MM522_19135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MM522_19140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MM522_19145	COG0512	Glutamine amidotransferase of anthranilate synthase
MM522_19150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MM522_19155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MM522_19160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MM522_19165	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MM522_19170	COG1396	sequence-specific DNA binding
MM522_19175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MM522_19180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MM522_19260	COG4463	regulation of RNA biosynthetic process
MM522_19265	COG3880	PFAM UvrB UvrC protein
MM522_19270	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MM522_19275	COG0542	response to heat
MM522_19280	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MM522_19285	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MM522_19290	COG4956	integral membrane protein (PIN domain superfamily)
MM522_19295	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MM522_19300	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MM522_19305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MM522_19310	COG1045	serine acetyltransferase
MM522_19315	COG0215	cysteine-tRNA ligase activity
MM522_19320	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MM522_19325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MM522_19330	COG3688	RNA-binding protein containing a PIN domain
MM522_19335	COG1595	DNA-templated transcription, initiation
MM522_19345	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MM522_19350	COG0250	Participates in transcription elongation, termination and antitermination
MM522_19360	COG0081	regulation of translation
MM522_19365	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MM522_19375	COG2813	Specifically methylates the guanine in position
MM522_19380	COG0085	RNA polymerase activity
MM522_19385	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MM522_19390	COG1358	cellular component organization or biogenesis
MM522_19395	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MM522_19400	COG0049	tRNA binding
MM522_19405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MM522_19410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MM522_19415	COG0596	Alpha beta hydrolase
MM522_19425	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MM522_19430	COG0088	Forms part of the polypeptide exit tunnel
MM522_19440	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MM522_19460	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MM522_19470	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MM522_19475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MM522_19485	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MM522_19495	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MM522_19500	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MM522_19505	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MM522_19510	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MM522_19520	COG0200	Binds to the 23S rRNA
MM522_19525	COG0201	protein transport
MM522_19530	COG0563	adenylate kinase activity
MM522_19535	COG0024	Methionine aminopeptidase
MM522_19540	COG2163	COG2163 Ribosomal protein L14E L6E L27E
MM522_19550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MM522_19555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MM522_19560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MM522_19565	COG0202	RNA polymerase activity
MM522_19570	COG0203	ribosomal protein L17
MM522_19575	COG1122	ATPase activity
MM522_19580	COG1122	ATPase activity
MM522_19585	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MM522_19590	COG0101	tRNA pseudouridine synthase activity
MM522_19595	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MM522_19600	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MM522_19605	COG2226	methyltransferase
MM522_19615	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM522_19620	COG0489	protein tyrosine kinase activity
MM522_19630	COG2194	sulfuric ester hydrolase activity
MM522_19635	COG0726	polysaccharide deacetylase
MM522_19810	COG0659	secondary active sulfate transmembrane transporter activity
MM522_19815	COG0385	Bile acid
MM522_19820	COG2819	hydrolase of the alpha beta superfamily
MM522_19825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM522_19830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM522_19835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MM522_19840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MM522_19840	COG2207	Transcriptional regulator
MM522_19845	COG3876	Protein conserved in bacteria
MM522_19850	COG1472	Belongs to the glycosyl hydrolase 3 family
MM522_19855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MM522_19860	COG1263	PTS System
MM522_19860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM522_19865	COG1737	Transcriptional regulator
MM522_19870	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MM522_19875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM522_19880	COG1683	Conserved Protein
MM522_19910	COG1595	DNA-templated transcription, initiation
MM522_19915	COG5662	AntiSigma factor
MM522_19920	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MM522_19925	COG4856	YbbR-like protein
MM522_19930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MM522_19935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MM522_19945	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MM522_19950	COG2169	Transcriptional regulator
MM522_19955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MM522_19960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MM522_19965	COG3002	Belongs to the UPF0753 family
MM522_19970	COG0288	reversible hydration of carbon dioxide
MM522_19980	COG5609	conserved protein (DUF2294)
MM522_19985	COG0640	Transcriptional regulator
MM522_19990	COG2814	Major facilitator Superfamily
MM522_20005	COG0596	Alpha beta hydrolase
MM522_20010	COG0745	RESPONSE REGULATOR receiver
MM522_20015	COG0642	Histidine kinase
MM522_20025	COG0515	serine threonine protein kinase
MM522_20040	COG1113	amino acid transport
MM522_20060	COG2124	cytochrome p450
MM522_20070	COG0531	amino acid
MM522_20075	COG0584	glycerophosphoryl diester phosphodiesterase
MM522_20080	COG2271	Major facilitator Superfamily
MM522_20090	COG0456	acetyltransferase
MM522_20090	COG1846	Transcriptional regulator
MM522_20095	COG2271	Major facilitator Superfamily
MM522_20105	COG3409	Peptidoglycan-binding domain 1 protein
MM522_20110	COG0697	spore germination
MM522_20115	COG1917	Cupin 2, conserved barrel domain protein
MM522_20115	COG2207	Transcriptional regulator
MM522_20120	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MM522_20125	COG3591	Belongs to the peptidase S1B family
MM522_20135	COG0596	Alpha beta hydrolase
MM522_20140	COG1183	phosphatidylcholine synthase activity
MM522_20145	COG0586	Pfam SNARE associated Golgi protein
MM522_20150	COG0688	phosphatidylethanolamine metabolic process
MM522_20165	COG1054	Belongs to the UPF0176 family
MM522_20170	COG1301	dicarboxylic acid transport
MM522_20175	COG1263	PTS System
MM522_20175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM522_20175	COG2190	(PTS) system
MM522_20180	COG0363	glucosamine-6-phosphate deaminase activity
MM522_20185	COG2188	Transcriptional regulator
MM522_20195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MM522_20200	COG0833	amino acid
MM522_20205	COG2040	homocysteine
MM522_20210	COG1115	amino acid carrier protein
MM522_20215	COG2066	Belongs to the glutaminase family
MM522_20220	COG4191	Histidine kinase
MM522_20225	COG0784	Response regulator, receiver
MM522_20230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MM522_20235	COG1012	belongs to the aldehyde dehydrogenase family
MM522_20240	COG2271	Major facilitator Superfamily
MM522_20245	COG4948	Mandelate Racemase Muconate Lactonizing
MM522_20250	COG2186	Transcriptional regulator
MM522_20255	COG2721	sulfolactate sulfo-lyase activity
MM522_20260	COG3173	Aminoglycoside phosphotransferase
MM522_20275	COG0745	RESPONSE REGULATOR receiver
MM522_20280	COG2205	protein histidine kinase activity
MM522_20285	COG1131	(ABC) transporter
MM522_20305	COG3773	Cell wall hydrolase
MM522_20310	COG2304	oxidoreductase activity
MM522_20320	COG3540	Alkaline phosphatase
MM522_20325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MM522_20330	COG0805	protein transport
MM522_20335	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MM522_20340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MM522_20345	COG0477	Major facilitator Superfamily
MM522_20350	COG1309	transcriptional regulator
MM522_20355	COG0252	asparaginase activity
MM522_20360	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MM522_20365	COG1714	RDD family
MM522_20370	COG1405	negative regulation of cell septum assembly
MM522_20370	COG3012	SEC-C Motif Domain Protein
MM522_20375	COG3290	protein histidine kinase activity
MM522_20380	COG3279	Response regulator of the LytR AlgR family
MM522_20385	COG4555	ABC transporter
MM522_20390	COG1668	transmembrane transport
MM522_20410	COG1595	DNA-templated transcription, initiation
MM522_20415	COG1595	DNA-templated transcription, initiation
MM522_20420	COG1876	peptidase activity
MM522_20425	COG0457	Tetratricopeptide repeat
MM522_20430	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_20435	COG0366	Alpha amylase catalytic
MM522_20440	COG0803	Belongs to the bacterial solute-binding protein 9 family
MM522_20445	COG1121	(ABC) transporter
MM522_20450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MM522_20455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM522_20460	COG2310	stress, protein
MM522_20465	COG2310	stress, protein
MM522_20470	COG2310	stress, protein
MM522_20475	COG0861	Integral membrane protein TerC family
MM522_20485	COG3853	Toxic anion resistance protein (TelA)
MM522_20490	COG0477	Major facilitator Superfamily
MM522_20495	COG2814	Major facilitator Superfamily
MM522_20500	COG0640	Transcriptional regulator
MM522_20505	COG0517	IMP dehydrogenase activity
MM522_20505	COG4175	Glycine betaine
MM522_20510	COG4176	ABC-type proline glycine betaine transport system permease component
MM522_20515	COG2113	Glycine betaine
MM522_20520	COG1473	amidohydrolase
MM522_20525	COG1288	antiporter activity
MM522_20535	COG0366	Alpha amylase catalytic
MM522_20540	COG0039	L-malate dehydrogenase activity
MM522_20545	COG1620	l-lactate permease
MM522_20550	COG2814	Major facilitator Superfamily
MM522_20555	COG1846	Transcriptional regulator
MM522_20560	COG1280	lysine exporter protein (LysE YggA)
MM522_20565	COG3403	YqcI/YcgG family
MM522_20570	COG1113	amino acid transport
MM522_20575	COG3665	Urea carboxylase-associated protein
MM522_20580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MM522_20585	COG1660	Displays ATPase and GTPase activities
MM522_20590	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MM522_20595	COG2226	methyltransferase
MM522_20600	COG0583	DNA-binding transcription factor activity
MM522_20605	COG3458	cephalosporin-C deacetylase activity
MM522_20610	COG3541	Predicted nucleotidyltransferase
MM522_20615	COG0506	proline dehydrogenase activity
MM522_20620	COG1012	belongs to the aldehyde dehydrogenase family
MM522_20625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MM522_20630	COG2508	Transcriptional regulator
MM522_20635	COG3689	TIGRFAM TIGR03943 family protein
MM522_20640	COG0701	Predicted permease
MM522_20645	COG2267	carboxylic ester hydrolase activity
MM522_20650	COG0492	ferredoxin-NADP+ reductase activity
MM522_20655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MM522_20655	COG1587	Uroporphyrinogen-III synthase
MM522_20660	COG2146	nitrite reductase [NAD(P)H] activity
MM522_20665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MM522_20670	COG0243	molybdopterin cofactor binding
MM522_20675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MM522_20680	COG2223	nitrite transmembrane transporter activity
MM522_20685	COG1469	GTP cyclohydrolase I activity
MM522_20690	COG1376	ErfK ybiS ycfS ynhG family protein
MM522_20705	COG0523	cobalamin synthesis protein
MM522_20710	COG0765	amino acid transport
MM522_20715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM522_20735	COG2723	6-phospho-beta-galactosidase activity
MM522_20745	COG3209	COG3209 Rhs family protein
MM522_20750	COG0840	transmembrane signaling receptor activity
MM522_20750	COG3290	protein histidine kinase activity
MM522_20755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MM522_20760	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MM522_20765	COG1733	regulation of RNA biosynthetic process
MM522_20770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_20790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_20795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM522_20800	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MM522_20805	COG2814	Major facilitator Superfamily
MM522_20815	COG0697	spore germination
MM522_20820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM522_20830	COG2364	Membrane
MM522_20835	COG1126	abc transporter atp-binding protein
MM522_20840	COG0765	amino acid transport
MM522_20845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM522_20850	COG0583	DNA-binding transcription factor activity
MM522_20855	COG0163	prenyltransferase activity
MM522_20860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MM522_20875	COG0596	Alpha beta hydrolase
MM522_20880	COG3104	oligopeptide transport
MM522_20885	COG5434	Belongs to the glycosyl hydrolase 28 family
MM522_20895	COG0697	spore germination
MM522_20905	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MM522_20910	COG1136	(ABC) transporter
MM522_20915	COG0577	efflux transmembrane transporter activity
MM522_20920	COG0745	RESPONSE REGULATOR receiver
MM522_20925	COG3850	Histidine kinase
MM522_20925	COG5002	protein histidine kinase activity
MM522_20930	COG0457	Tetratricopeptide repeat
MM522_20950	COG0527	aspartate kinase activity
MM522_20955	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM522_20960	COG4605	iron ion homeostasis
MM522_20965	COG4604	ABC transporter, ATP-binding protein
MM522_20970	COG4607	ABC-type enterochelin transport system periplasmic component
MM522_20975	COG2814	Major facilitator Superfamily
MM522_20980	COG1309	transcriptional regulator
MM522_20985	COG0778	Nitroreductase
MM522_20990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MM522_20995	COG0640	Transcriptional regulator
MM522_21000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM522_21005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MM522_21010	COG1012	belongs to the aldehyde dehydrogenase family
MM522_21015	COG4975	Glucose uptake
MM522_21020	COG1028	Short-chain dehydrogenase reductase Sdr
MM522_21025	COG4549	nuclear export factor GLE1
MM522_21030	COG1276	copper resistance
MM522_21030	COG2372	response to copper ion
MM522_21035	COG1349	DNA-binding transcription factor activity
MM522_21045	COG2213	PTS system mannitol-specific
MM522_21050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system