locus-tag	class	description
KS08_00010	COG0592	DNA-directed DNA polymerase activity
KS08_00015	COG2501	S4 domain
KS08_00030	COG0187	DNA topoisomerase II activity
KS08_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KS08_00070	COG0516	GMP reductase activity
KS08_00070	COG0517	IMP dehydrogenase activity
KS08_00075	COG1686	Belongs to the peptidase S11 family
KS08_00095	COG1929	Belongs to the glycerate kinase type-1 family
KS08_00105	COG1428	Deoxynucleoside kinase
KS08_00110	COG1428	Deoxynucleoside kinase
KS08_00115	COG1388	LysM domain
KS08_00115	COG3858	chitin binding
KS08_00120	COG1335	isochorismatase
KS08_00125	COG0590	tRNA wobble adenosine to inosine editing
KS08_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KS08_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KS08_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KS08_00190	COG3853	Toxic anion resistance protein (TelA)
KS08_00195	COG1982	Orn Lys Arg decarboxylase major
KS08_00205	COG3870	Protein conserved in bacteria
KS08_00210	COG1728	Protein conserved in bacteria
KS08_00215	COG0470	DNA polymerase III
KS08_00220	COG1774	PSP1 C-terminal conserved region
KS08_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KS08_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KS08_00245	COG2002	toxin-antitoxin pair type II binding
KS08_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS08_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS08_00255	COG0084	hydrolase, TatD family'
KS08_00260	COG3584	3D domain protein
KS08_00260	COG3583	domain protein
KS08_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KS08_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KS08_00280	COG4466	Protein conserved in bacteria
KS08_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KS08_00300	COG0251	oxidation-reduction process
KS08_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KS08_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KS08_00340	COG2002	toxin-antitoxin pair type II binding
KS08_00345	COG2244	polysaccharide biosynthetic process
KS08_00350	COG3956	TIGRFAM MazG family protein
KS08_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KS08_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KS08_00375	COG1098	S1 RNA binding domain
KS08_00390	COG2208	phosphoserine phosphatase activity
KS08_00395	COG2304	oxidoreductase activity
KS08_00400	COG0515	serine threonine protein kinase
KS08_00405	COG0037	tRNA processing
KS08_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KS08_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KS08_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KS08_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KS08_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
KS08_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KS08_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KS08_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KS08_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KS08_00470	COG1396	sequence-specific DNA binding
KS08_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KS08_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KS08_00500	COG4463	regulation of RNA biosynthetic process
KS08_00505	COG3880	PFAM UvrB UvrC protein
KS08_00515	COG0542	response to heat
KS08_00520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KS08_00525	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KS08_00530	COG4956	integral membrane protein (PIN domain superfamily)
KS08_00555	COG1045	serine acetyltransferase
KS08_00565	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KS08_00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KS08_00575	COG3688	RNA-binding protein containing a PIN domain
KS08_00580	COG1595	DNA-templated transcription, initiation
KS08_00585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KS08_00590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KS08_00595	COG0250	Participates in transcription elongation, termination and antitermination
KS08_00600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KS08_00615	COG0222	ribosome binding
KS08_00620	COG2813	Specifically methylates the guanine in position
KS08_00635	COG1358	cellular component organization or biogenesis
KS08_00660	COG0596	Alpha beta hydrolase
KS08_00665	COG0051	transcription antitermination factor activity, RNA binding
KS08_00680	COG0089	rRNA binding
KS08_00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KS08_00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KS08_00705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KS08_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
KS08_00720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KS08_00760	COG1841	ribosomal large subunit assembly
KS08_00770	COG0201	protein transport
KS08_00780	COG0024	Methionine aminopeptidase
KS08_00790	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KS08_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KS08_00820	COG1122	ATPase activity
KS08_00825	COG1122	ATPase activity
KS08_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KS08_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KS08_00850	COG2226	methyltransferase
KS08_00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS08_00865	COG0489	protein tyrosine kinase activity
KS08_00875	COG2194	sulfuric ester hydrolase activity
KS08_00880	COG0726	polysaccharide deacetylase
KS08_00900	COG0738	Major facilitator superfamily
KS08_00915	COG1063	alcohol dehydrogenase
KS08_00920	COG0659	secondary active sulfate transmembrane transporter activity
KS08_00925	COG0385	Bile acid
KS08_00930	COG2819	hydrolase of the alpha beta superfamily
KS08_00935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_00940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_00945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS08_00950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS08_00950	COG2207	Transcriptional regulator
KS08_00955	COG3876	Protein conserved in bacteria
KS08_00960	COG1472	Belongs to the glycosyl hydrolase 3 family
KS08_00965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KS08_00970	COG1263	PTS System
KS08_00970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_00980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS08_00985	COG1683	Conserved Protein
KS08_01015	COG1595	DNA-templated transcription, initiation
KS08_01020	COG5662	AntiSigma factor
KS08_01025	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KS08_01030	COG4856	YbbR-like protein
KS08_01075	COG1346	cytolysis
KS08_01080	COG1380	Effector of murein hydrolase LrgA
KS08_01085	COG1846	Transcriptional regulator
KS08_01090	COG1113	amino acid transport
KS08_01095	COG1011	Hydrolase
KS08_01100	COG4585	Histidine kinase
KS08_01105	COG2197	response regulator
KS08_01110	COG1131	(ABC) transporter
KS08_01120	COG1511	domain protein
KS08_01120	COG0842	Transport permease protein
KS08_01150	COG0531	amino acid
KS08_01160	COG0584	glycerophosphoryl diester phosphodiesterase
KS08_01165	COG2271	Major facilitator Superfamily
KS08_01175	COG2368	4-hydroxyphenylacetate
KS08_01190	COG0371	Dehydrogenase
KS08_01200	COG1183	phosphatidylcholine synthase activity
KS08_01205	COG0586	Pfam SNARE associated Golgi protein
KS08_01210	COG0688	phosphatidylethanolamine metabolic process
KS08_01225	COG1301	dicarboxylic acid transport
KS08_01230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KS08_01235	COG0833	amino acid
KS08_01240	COG2040	homocysteine
KS08_01245	COG1115	amino acid carrier protein
KS08_01250	COG2066	Belongs to the glutaminase family
KS08_01255	COG4191	Histidine kinase
KS08_01260	COG0784	Response regulator, receiver
KS08_01265	COG3173	Aminoglycoside phosphotransferase
KS08_01280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS08_01285	COG0778	Nitroreductase
KS08_01290	COG0346	lactoylglutathione lyase activity
KS08_01295	COG2259	Doxx family
KS08_01300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_01315	COG3773	Cell wall hydrolase
KS08_01320	COG3540	Alkaline phosphatase
KS08_01325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KS08_01330	COG0805	protein transport
KS08_01335	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KS08_01340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KS08_01345	COG0477	Major facilitator Superfamily
KS08_01350	COG1309	transcriptional regulator
KS08_01355	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KS08_01360	COG3012	SEC-C Motif Domain Protein
KS08_01360	COG1405	negative regulation of cell septum assembly
KS08_01365	COG0667	Aldo Keto reductase
KS08_01375	COG1595	DNA-templated transcription, initiation
KS08_01380	COG1595	DNA-templated transcription, initiation
KS08_01385	COG1876	peptidase activity
KS08_01390	COG0457	Tetratricopeptide repeat
KS08_01395	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_01400	COG0366	Alpha amylase catalytic
KS08_01410	COG1695	Transcriptional regulator
KS08_01415	COG0803	Belongs to the bacterial solute-binding protein 9 family
KS08_01420	COG1121	(ABC) transporter
KS08_01425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KS08_01430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_01435	COG2310	stress, protein
KS08_01440	COG2310	stress, protein
KS08_01445	COG2310	stress, protein
KS08_01450	COG0861	Integral membrane protein TerC family
KS08_01460	COG3853	Toxic anion resistance protein (TelA)
KS08_01465	COG0477	Major facilitator Superfamily
KS08_01470	COG4175	Glycine betaine
KS08_01470	COG0517	IMP dehydrogenase activity
KS08_01475	COG4176	ABC-type proline glycine betaine transport system permease component
KS08_01480	COG2113	Glycine betaine
KS08_01485	COG1473	amidohydrolase
KS08_01490	COG1288	antiporter activity
KS08_01500	COG1714	RDD family
KS08_01510	COG2814	Major facilitator Superfamily
KS08_01515	COG1846	Transcriptional regulator
KS08_01520	COG1280	lysine exporter protein (LysE YggA)
KS08_01525	COG3403	YqcI/YcgG family
KS08_01530	COG1113	amino acid transport
KS08_01535	COG3665	Urea carboxylase-associated protein
KS08_01545	COG1082	Xylose isomerase domain protein TIM barrel
KS08_01550	COG2271	Major facilitator Superfamily
KS08_01555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KS08_01560	COG3458	cephalosporin-C deacetylase activity
KS08_01565	COG3541	Predicted nucleotidyltransferase
KS08_01570	COG0506	proline dehydrogenase activity
KS08_01575	COG1012	belongs to the aldehyde dehydrogenase family
KS08_01580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS08_01585	COG2508	Transcriptional regulator
KS08_01595	COG1587	Uroporphyrinogen-III synthase
KS08_01595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KS08_01600	COG2146	nitrite reductase [NAD(P)H] activity
KS08_01605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KS08_01610	COG2223	nitrite transmembrane transporter activity
KS08_01615	COG0523	cobalamin synthesis protein
KS08_01620	COG1063	alcohol dehydrogenase
KS08_01625	COG1714	RDD family
KS08_01635	COG2723	6-phospho-beta-galactosidase activity
KS08_01645	COG3209	COG3209 Rhs family protein
KS08_01650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KS08_01655	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KS08_01660	COG1733	regulation of RNA biosynthetic process
KS08_01670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_01675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_01680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_01685	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KS08_01700	COG2364	Membrane
KS08_01705	COG1126	abc transporter atp-binding protein
KS08_01710	COG0765	amino acid transport
KS08_01715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_01720	COG0583	DNA-binding transcription factor activity
KS08_01725	COG0163	prenyltransferase activity
KS08_01730	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KS08_01745	COG3104	oligopeptide transport
KS08_01750	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_01760	COG0697	spore germination
KS08_01770	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KS08_01785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_01790	COG0765	amino acid transport
KS08_01795	COG1126	abc transporter atp-binding protein
KS08_01805	COG2079	MmgE PrpD family protein
KS08_01810	COG1136	(ABC) transporter
KS08_01815	COG0577	efflux transmembrane transporter activity
KS08_01820	COG0745	RESPONSE REGULATOR receiver
KS08_01825	COG3850	Histidine kinase
KS08_01825	COG5002	protein histidine kinase activity
KS08_01830	COG0457	Tetratricopeptide repeat
KS08_01845	COG0527	aspartate kinase activity
KS08_01850	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_01855	COG4605	iron ion homeostasis
KS08_01860	COG4604	ABC transporter, ATP-binding protein
KS08_01865	COG4607	ABC-type enterochelin transport system periplasmic component
KS08_01870	COG2814	Major facilitator Superfamily
KS08_01875	COG1309	transcriptional regulator
KS08_01880	COG0778	Nitroreductase
KS08_01885	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KS08_01890	COG0640	Transcriptional regulator
KS08_01895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_01900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KS08_01905	COG1012	belongs to the aldehyde dehydrogenase family
KS08_01910	COG4975	Glucose uptake
KS08_01915	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_01920	COG4549	nuclear export factor GLE1
KS08_01925	COG1276	copper resistance
KS08_01925	COG2372	response to copper ion
KS08_01930	COG1349	DNA-binding transcription factor activity
KS08_01940	COG2213	PTS system mannitol-specific
KS08_01945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_01955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KS08_01965	COG0561	phosphatase activity
KS08_01975	COG1914	H( )-stimulated, divalent metal cation uptake system
KS08_01985	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KS08_01990	COG1984	allophanate hydrolase subunit 2
KS08_01995	COG1414	Transcriptional regulator
KS08_02000	COG2755	lipolytic protein G-D-S-L family
KS08_02010	COG2329	Antibiotic biosynthesis monooxygenase
KS08_02015	COG0768	penicillin binding
KS08_02020	COG4989	oxidoreductase activity
KS08_02025	COG3711	transcriptional antiterminator
KS08_02030	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_02035	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_02040	COG1917	Cupin 2, conserved barrel domain protein
KS08_02045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS08_02050	COG3871	stress protein (general stress protein 26)
KS08_02060	COG2814	Major facilitator Superfamily
KS08_02065	COG1522	sequence-specific DNA binding
KS08_02070	COG0551	DNA topoisomerase type I activity
KS08_02070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KS08_02075	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KS08_02080	COG3706	GGDEF domain
KS08_02085	COG5298	Protein conserved in bacteria
KS08_02100	COG0531	amino acid
KS08_02105	COG0028	Belongs to the TPP enzyme family
KS08_02115	COG1388	LysM domain
KS08_02135	COG0457	Tetratricopeptide repeat
KS08_02150	COG1914	H( )-stimulated, divalent metal cation uptake system
KS08_02165	COG4876	unkown
KS08_02175	COG2076	Multidrug Resistance protein
KS08_02180	COG2217	Heavy metal translocating P-type atpase
KS08_02185	COG3729	General stress protein
KS08_02190	COG0662	Cupin 2, conserved barrel domain protein
KS08_02195	COG2329	Antibiotic biosynthesis monooxygenase
KS08_02200	COG3546	catalase activity
KS08_02205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KS08_02210	COG3290	protein histidine kinase activity
KS08_02215	COG4565	transcriptional regulatory protein
KS08_02220	COG1301	dicarboxylic acid transport
KS08_02225	COG0628	permease
KS08_02230	COG1131	(ABC) transporter
KS08_02235	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KS08_02245	COG1960	acyl-CoA dehydrogenase activity
KS08_02260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS08_02265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_02275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KS08_02280	COG0513	Belongs to the DEAD box helicase family
KS08_02285	COG3402	PFAM membrane-flanked domain
KS08_02290	COG3428	Bacterial PH domain
KS08_02295	COG0705	Rhomboid family
KS08_02305	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KS08_02310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KS08_02315	COG0864	Transcriptional regulator
KS08_02320	COG2337	Toxic component of a toxin-antitoxin (TA) module
KS08_02325	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_02330	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_02335	COG2172	sigma factor antagonist activity
KS08_02340	COG2208	phosphoserine phosphatase activity
KS08_02345	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_02355	COG1191	sigma factor activity
KS08_02360	COG2208	phosphoserine phosphatase activity
KS08_02365	COG2183	response to ionizing radiation
KS08_02420	COG1764	response to oxidative stress
KS08_02425	COG1846	Transcriptional regulator
KS08_02435	COG0456	acetyltransferase
KS08_02435	COG1846	Transcriptional regulator
KS08_02440	COG2271	Major facilitator Superfamily
KS08_02445	COG4124	Belongs to the glycosyl hydrolase 26 family
KS08_02465	COG1959	2 iron, 2 sulfur cluster binding
KS08_02475	COG1278	Cold shock
KS08_02480	COG1794	racemase activity, acting on amino acids and derivatives
KS08_02495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_02500	COG0477	Major facilitator Superfamily
KS08_02505	COG3621	Patatin-like phospholipase
KS08_02515	COG0277	FAD linked oxidase domain protein
KS08_02535	COG0662	Cupin 2, conserved barrel domain protein
KS08_02540	COG0456	acetyltransferase
KS08_02545	COG3708	Transcriptional regulator
KS08_02545	COG2207	Transcriptional regulator
KS08_02570	COG1064	alcohol dehydrogenase
KS08_02575	COG0789	Transcriptional regulator
KS08_02585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_02590	COG2808	Putative FMN-binding domain
KS08_02595	COG2814	Major facilitator Superfamily
KS08_02600	COG1309	transcriptional regulator
KS08_02605	COG0697	spore germination
KS08_02610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_02615	COG5577	PFAM Coat F domain
KS08_02625	COG1063	alcohol dehydrogenase
KS08_02630	COG5577	PFAM Coat F domain
KS08_02640	COG2409	Drug exporters of the RND superfamily
KS08_02645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KS08_02655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS08_02660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_02670	COG2814	Major facilitator Superfamily
KS08_02675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KS08_02685	COG0730	response to heat
KS08_02690	COG0456	acetyltransferase
KS08_02695	COG0789	Transcriptional regulator
KS08_02695	COG4978	Transcriptional regulator
KS08_02700	COG0697	spore germination
KS08_02705	COG1051	belongs to the nudix hydrolase family
KS08_02710	COG0596	Alpha beta hydrolase
KS08_02715	COG0473	3-isopropylmalate dehydrogenase activity
KS08_02720	COG1802	Transcriptional regulator
KS08_02725	COG1819	glycosyl
KS08_02735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KS08_02740	COG1388	LysM domain
KS08_02745	COG2814	Major facilitator Superfamily
KS08_02750	COG2188	Transcriptional regulator
KS08_02755	COG2186	Transcriptional regulator
KS08_02760	COG2807	transmembrane transport
KS08_02765	COG2076	Multidrug Resistance protein
KS08_02770	COG2076	Multidrug Resistance protein
KS08_02775	COG1309	transcriptional regulator
KS08_02780	COG0531	amino acid
KS08_02790	COG3832	glyoxalase III activity
KS08_02795	COG0604	alcohol dehydrogenase
KS08_02800	COG2814	Major facilitator Superfamily
KS08_02840	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KS08_02845	COG0802	atpase or kinase
KS08_02850	COG1214	PFAM Peptidase M22, glycoprotease
KS08_02855	COG0456	acetyltransferase
KS08_02860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KS08_02865	COG0488	(ABC) transporter
KS08_02880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KS08_02885	COG0805	protein transport
KS08_02895	COG1266	CAAX protease self-immunity
KS08_02900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KS08_02910	COG3409	Peptidoglycan-binding domain 1 protein
KS08_02925	COG0457	Tetratricopeptide repeat
KS08_02930	COG1063	alcohol dehydrogenase
KS08_02935	COG2211	Major facilitator Superfamily
KS08_02940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KS08_02950	COG1842	Phage shock protein A
KS08_02955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KS08_02960	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KS08_02965	COG4260	virion core protein, lumpy skin disease virus
KS08_02970	COG2755	lipolytic protein G-D-S-L family
KS08_02970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KS08_02980	COG1595	DNA-templated transcription, initiation
KS08_02985	COG1063	alcohol dehydrogenase
KS08_02990	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KS08_02995	COG0823	Involved in the tonB-independent uptake of proteins
KS08_03010	COG2132	Multicopper oxidase
KS08_03015	COG1113	amino acid transport
KS08_03025	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS08_03030	COG0714	Associated with various cellular activities
KS08_03035	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KS08_03040	COG1305	Transglutaminase-like
KS08_03060	COG2252	PERMEase
KS08_03065	COG3064	Membrane
KS08_03085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KS08_03090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KS08_03095	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KS08_03100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KS08_03105	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KS08_03120	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KS08_03130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KS08_03135	COG0138	bifunctional purine biosynthesis protein purh
KS08_03140	COG0151	Belongs to the GarS family
KS08_03145	COG1522	sequence-specific DNA binding
KS08_03150	COG0531	amino acid
KS08_03160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KS08_03165	COG1470	cell adhesion involved in biofilm formation
KS08_03170	COG4496	protein, YerC YecD
KS08_03175	COG0069	glutamate synthase activity
KS08_03190	COG0210	DNA helicase
KS08_03200	COG4851	CamS sex pheromone cAM373 precursor
KS08_03205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KS08_03210	COG1285	pathogenesis
KS08_03215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS08_03235	COG1309	transcriptional regulator
KS08_03240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KS08_03245	COG1597	lipid kinase activity
KS08_03250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KS08_03260	COG1131	(ABC) transporter
KS08_03315	COG3546	catalase activity
KS08_03320	COG0454	-acetyltransferase
KS08_03330	COG2323	membrane
KS08_03335	COG2329	Antibiotic biosynthesis monooxygenase
KS08_03340	COG0346	lactoylglutathione lyase activity
KS08_03345	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_03350	COG5583	Uncharacterized small protein (DUF2292)
KS08_03355	COG0196	riboflavin kinase activity
KS08_03360	COG0670	Belongs to the BI1 family
KS08_03365	COG1846	Transcriptional regulator
KS08_03370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KS08_03380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KS08_03380	COG2124	cytochrome p450
KS08_03390	COG1368	sulfuric ester hydrolase activity
KS08_03395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KS08_03400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS08_03405	COG1442	glycosyl transferase family 8
KS08_03410	COG1216	Glycosyl transferase, family 2
KS08_03415	COG1442	glycosyl transferase family 8
KS08_03420	COG2223	nitrite transmembrane transporter activity
KS08_03425	COG0531	amino acid
KS08_03430	COG1012	belongs to the aldehyde dehydrogenase family
KS08_03435	COG0840	transmembrane signaling receptor activity
KS08_03440	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_03445	COG0457	Tetratricopeptide repeat
KS08_03445	COG0463	Glycosyl transferase, family 2
KS08_03450	COG0488	(ABC) transporter
KS08_03455	COG0789	Transcriptional regulator
KS08_03460	COG2814	Major facilitator Superfamily
KS08_03465	COG0488	(ABC) transporter
KS08_03470	COG0513	Belongs to the DEAD box helicase family
KS08_03475	COG2130	NADP-dependent
KS08_03490	COG3866	Pectate lyase
KS08_03495	COG0471	metal ion transport
KS08_03515	COG2972	Histidine kinase
KS08_03515	COG0745	RESPONSE REGULATOR receiver
KS08_03530	COG3764	Sortase (surface protein transpeptidase)
KS08_03535	COG3290	protein histidine kinase activity
KS08_03540	COG4565	transcriptional regulatory protein
KS08_03545	COG3181	Tripartite tricarboxylate transporter family receptor
KS08_03550	COG2851	Citrate transporter
KS08_03555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_03560	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KS08_03570	COG2258	MOSC domain
KS08_03590	COG0024	Methionine aminopeptidase
KS08_03595	COG1263	PTS System
KS08_03595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_03605	COG1368	sulfuric ester hydrolase activity
KS08_03615	COG0071	Belongs to the small heat shock protein (HSP20) family
KS08_03630	COG1263	PTS System
KS08_03630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_03635	COG0366	Alpha amylase catalytic
KS08_03640	COG2188	Transcriptional regulator
KS08_03645	COG0778	Nitroreductase
KS08_03660	COG0737	Belongs to the 5'-nucleotidase family
KS08_03665	COG0693	protein deglycase activity
KS08_03675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KS08_03685	COG2814	Major facilitator Superfamily
KS08_03695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KS08_03700	COG4980	gas vesicle protein
KS08_03705	COG1295	ribonuclease BN
KS08_03715	COG0477	Major facilitator Superfamily
KS08_03720	COG0387	Pfam Sodium calcium exchanger
KS08_03730	COG0668	transmembrane transport
KS08_03735	COG0535	radical SAM domain protein
KS08_03745	COG0726	polysaccharide deacetylase
KS08_03750	COG2084	Dehydrogenase
KS08_03760	COG0598	Magnesium transport protein CorA
KS08_03765	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KS08_03770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KS08_03785	COG1132	(ABC) transporter
KS08_03790	COG0515	serine threonine protein kinase
KS08_03800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KS08_03805	COG4637	Psort location Cytoplasmic, score
KS08_03810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KS08_03815	COG0022	dehydrogenase e1 component
KS08_03820	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS08_03825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KS08_03830	COG3284	Transcriptional regulator
KS08_03840	COG1486	melibiose metabolic process
KS08_03845	COG1737	Transcriptional regulator
KS08_03850	COG1263	PTS System
KS08_03850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_03855	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_03860	COG1132	(ABC) transporter
KS08_03865	COG1132	(ABC) transporter
KS08_03870	COG2259	Doxx family
KS08_03875	COG2514	catechol 2,3-dioxygenase activity
KS08_03885	COG1695	Transcriptional regulator
KS08_03890	COG2249	NAD(P)H dehydrogenase (quinone) activity
KS08_03895	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KS08_03900	COG2732	(Barnase) inhibitor
KS08_03905	COG2318	DinB family
KS08_03910	COG2814	Major facilitator Superfamily
KS08_03915	COG1846	Transcriptional regulator
KS08_03920	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KS08_03920	COG0392	lysyltransferase activity
KS08_03925	COG0384	phenazine biosynthesis protein PhzF
KS08_03930	COG0778	Nitroreductase
KS08_03945	COG1090	epimerase
KS08_03960	COG2814	Major facilitator Superfamily
KS08_03970	COG3591	Belongs to the peptidase S1B family
KS08_03985	COG3103	Sh3 type 3 domain protein
KS08_03990	COG5658	integral membrane protein
KS08_03995	COG0596	Alpha beta hydrolase
KS08_04000	COG0463	Glycosyl transferase, family 2
KS08_04005	COG4485	Bacterial membrane protein, YfhO
KS08_04010	COG1988	membrane-bound metal-dependent
KS08_04015	COG1194	a g-specific adenine glycosylase
KS08_04025	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_04045	COG1132	(ABC) transporter
KS08_04050	COG4129	membrane
KS08_04060	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KS08_04065	COG0735	belongs to the Fur family
KS08_04175	COG1757	Na H antiporter
KS08_04180	COG3340	Belongs to the peptidase S51 family
KS08_04190	COG0277	FAD linked oxidase domain protein
KS08_04200	COG0747	negative chemotaxis
KS08_04205	COG0601	transmembrane transport
KS08_04210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS08_04215	COG0444	Belongs to the ABC transporter superfamily
KS08_04225	COG0753	catalase activity
KS08_04235	COG1116	anion transmembrane transporter activity
KS08_04240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KS08_04245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KS08_04275	COG1476	TRANSCRIPTIONal
KS08_04285	COG3382	B3 4 domain protein
KS08_04290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KS08_04300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KS08_04305	COG0789	Transcriptional regulator
KS08_04310	COG1664	Polymer-forming cytoskeletal
KS08_04315	COG1664	Polymer-forming cytoskeletal
KS08_04320	COG2766	serine protein kinase
KS08_04330	COG1846	Transcriptional regulator
KS08_04335	COG1566	PFAM secretion protein HlyD family protein
KS08_04340	COG2814	Major facilitator Superfamily
KS08_04345	COG0655	NAD(P)H dehydrogenase (quinone) activity
KS08_04360	COG1725	Transcriptional regulator
KS08_04365	COG1131	(ABC) transporter
KS08_04370	COG1131	(ABC) transporter
KS08_04375	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KS08_04380	COG1278	Cold shock
KS08_04385	COG1464	Belongs to the NlpA lipoprotein family
KS08_04390	COG3706	GGDEF domain
KS08_04395	COG1823	symporter activity
KS08_04400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS08_04420	COG5577	PFAM Coat F domain
KS08_04425	COG4085	toxin activity
KS08_04425	COG1525	nuclease
KS08_04425	COG0737	Belongs to the 5'-nucleotidase family
KS08_04430	COG3764	Sortase (surface protein transpeptidase)
KS08_04435	COG0564	pseudouridine synthase activity
KS08_04445	COG0517	IMP dehydrogenase activity
KS08_04450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KS08_04455	COG3153	acetyltransferase
KS08_04455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KS08_04460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KS08_04465	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KS08_04470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KS08_04480	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KS08_04485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KS08_04490	COG4585	Histidine kinase
KS08_04490	COG2203	Gaf domain
KS08_04495	COG2197	response regulator
KS08_04500	COG0431	NADPH-dependent FMN reductase
KS08_04515	COG1388	LysM domain
KS08_04515	COG0791	NLP P60 protein
KS08_04520	COG1959	2 iron, 2 sulfur cluster binding
KS08_04525	COG0668	transmembrane transport
KS08_04530	COG2719	SpoVR family
KS08_04535	COG1785	Belongs to the alkaline phosphatase family
KS08_04540	COG0791	NLP P60 protein
KS08_04540	COG1388	LysM domain
KS08_04545	COG0583	DNA-binding transcription factor activity
KS08_04550	COG0372	Belongs to the citrate synthase family
KS08_04555	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_04560	COG0531	amino acid
KS08_04565	COG0733	neurotransmitter:sodium symporter activity
KS08_04580	COG1595	DNA-templated transcription, initiation
KS08_04585	COG0204	Acyl-transferase
KS08_04590	COG1253	flavin adenine dinucleotide binding
KS08_04595	COG0789	Transcriptional regulator
KS08_04600	COG0436	Aminotransferase
KS08_04605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KS08_04610	COG1253	flavin adenine dinucleotide binding
KS08_04615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KS08_04620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KS08_04625	COG0584	glycerophosphoryl diester phosphodiesterase
KS08_04635	COG0668	transmembrane transport
KS08_04640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KS08_04645	COG0726	polysaccharide deacetylase
KS08_04650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KS08_04655	COG3226	Transcriptional regulator
KS08_04665	COG0589	response to stress
KS08_04670	COG1132	(ABC) transporter
KS08_04675	COG1132	(ABC) transporter
KS08_04680	COG0702	epimerase
KS08_04700	COG0189	ligase activity
KS08_04705	COG0189	ligase activity
KS08_04720	COG0561	phosphatase activity
KS08_04725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KS08_04735	COG0475	glutathione-regulated potassium exporter activity
KS08_04740	COG0490	domain, Protein
KS08_04750	COG1024	Enoyl-CoA hydratase
KS08_04760	COG4152	abc transporter atp-binding protein
KS08_04765	COG1668	transmembrane transport
KS08_04770	COG0420	3'-5' exonuclease activity
KS08_04775	COG4717	serine-type aminopeptidase activity
KS08_04790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KS08_04825	COG4980	gas vesicle protein
KS08_04840	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KS08_04845	COG0537	adenosine 5'-monophosphoramidase activity
KS08_04850	COG1131	(ABC) transporter
KS08_04855	COG4473	ABC transporter
KS08_04865	COG1473	amidohydrolase
KS08_04870	COG3069	C4-dicarboxylate transmembrane transporter activity
KS08_04875	COG2329	Antibiotic biosynthesis monooxygenase
KS08_04880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS08_04900	COG1309	transcriptional regulator
KS08_04905	COG1511	domain protein
KS08_04910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KS08_04920	COG1363	Peptidase, m42
KS08_04925	COG1301	dicarboxylic acid transport
KS08_04935	COG1234	tRNA 3'-trailer cleavage
KS08_04940	COG0095	Lipoate-protein ligase
KS08_04945	COG0702	epimerase
KS08_04950	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_04960	COG0501	Belongs to the peptidase M48B family
KS08_04965	COG1404	Belongs to the peptidase S8 family
KS08_04970	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KS08_04975	COG0406	alpha-ribazole phosphatase activity
KS08_04980	COG0183	Belongs to the thiolase family
KS08_04985	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_04990	COG1268	BioY protein
KS08_04995	COG0840	transmembrane signaling receptor activity
KS08_05000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS08_05000	COG0723	plastoquinol--plastocyanin reductase activity
KS08_05005	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_05015	COG4903	ComK protein
KS08_05020	COG5646	InterPro IPR014922
KS08_05045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS08_05060	COG0398	Pfam SNARE associated Golgi protein
KS08_05065	COG0681	Belongs to the peptidase S26 family
KS08_05070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KS08_05075	COG1846	Transcriptional regulator
KS08_05080	COG3180	Ammonia monooxygenase
KS08_05085	COG2814	Major facilitator Superfamily
KS08_05095	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KS08_05100	COG2323	membrane
KS08_05115	COG0420	3'-5' exonuclease activity
KS08_05120	COG0419	ATPase involved in DNA repair
KS08_05125	COG1403	HNH endonuclease
KS08_05165	COG0179	Fumarylacetoacetate (FAA) hydrolase
KS08_05175	COG1404	Belongs to the peptidase S8 family
KS08_05185	COG0367	asparagine synthase
KS08_05190	COG1562	ergosterol biosynthetic process
KS08_05195	COG0534	Mate efflux family protein
KS08_05200	COG2207	Transcriptional regulator
KS08_05200	COG1917	Cupin 2, conserved barrel domain protein
KS08_05205	COG1609	Transcriptional regulator
KS08_05210	COG0673	inositol 2-dehydrogenase activity
KS08_05215	COG2318	DinB family
KS08_05220	COG1279	arginine transmembrane transporter activity
KS08_05225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_05230	COG1357	PFAM Pentapeptide repeats (8 copies)
KS08_05235	COG2153	protein acetylation
KS08_05240	COG0646	methionine synthase
KS08_05240	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KS08_05250	COG2996	Protein conserved in bacteria
KS08_05260	COG0840	transmembrane signaling receptor activity
KS08_05265	COG2124	cytochrome p450
KS08_05270	COG1307	EDD domain protein, DegV family
KS08_05275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_05295	COG0561	phosphatase activity
KS08_05300	COG1073	alpha beta
KS08_05305	COG2151	metal-sulfur cluster biosynthetic enzyme
KS08_05315	COG0277	FAD linked oxidase domain protein
KS08_05320	COG2271	Major facilitator Superfamily
KS08_05340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KS08_05345	COG0505	Belongs to the CarA family
KS08_05350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KS08_05355	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KS08_05370	COG2267	carboxylic ester hydrolase activity
KS08_05380	COG1744	ABC transporter substrate-binding protein PnrA-like
KS08_05395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KS08_05400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KS08_05405	COG5504	Zn-dependent protease
KS08_05410	COG0444	Belongs to the ABC transporter superfamily
KS08_05415	COG4608	Belongs to the ABC transporter superfamily
KS08_05425	COG0601	transmembrane transport
KS08_05430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS08_05440	COG0180	Tryptophanyl-tRNA synthetase
KS08_05445	COG4166	transmembrane transport
KS08_05450	COG0601	transmembrane transport
KS08_05455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS08_05460	COG0444	Belongs to the ABC transporter superfamily
KS08_05465	COG4608	Belongs to the ABC transporter superfamily
KS08_05475	COG0456	acetyltransferase
KS08_05480	COG1393	Belongs to the ArsC family
KS08_05485	COG0861	Integral membrane protein TerC family
KS08_05490	COG4862	establishment of competence for transformation
KS08_05495	COG4469	Competence protein
KS08_05500	COG1164	Oligoendopeptidase f
KS08_05520	COG2346	COG2346, Truncated hemoglobins
KS08_05525	COG0741	lytic transglycosylase activity
KS08_05530	COG4116	CYTH
KS08_05540	COG2357	RelA SpoT domain protein
KS08_05545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KS08_05550	COG0564	pseudouridine synthase activity
KS08_05560	COG0475	glutathione-regulated potassium exporter activity
KS08_05560	COG0569	domain protein
KS08_05565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KS08_05570	COG0352	thiamine-phosphate diphosphorylase activity
KS08_05575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS08_05580	COG2104	thiamine diphosphate biosynthetic process
KS08_05590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KS08_05595	COG0351	phosphomethylpyrimidine kinase
KS08_05600	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KS08_05660	COG0210	DNA helicase
KS08_05670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_05680	COG1131	(ABC) transporter
KS08_05690	COG2153	protein acetylation
KS08_05700	COG2382	esterase
KS08_05705	COG0626	cystathionine gamma-synthase activity
KS08_05710	COG0626	cystathionine gamma-synthase activity
KS08_05720	COG0582	viral genome integration into host DNA
KS08_05725	COG2856	Zn peptidase
KS08_05735	COG1525	nuclease
KS08_05740	COG3620	sequence-specific DNA binding
KS08_05790	COG3935	DnaD domain protein
KS08_05795	COG1484	DNA-dependent DNA replication
KS08_05805	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KS08_05880	COG3677	Transposase
KS08_05895	COG5484	DNA packaging
KS08_05970	COG5280	Phage tail tape measure protein TP901
KS08_05970	COG3953	SLT domain
KS08_06060	COG5444	nuclease activity
KS08_06095	COG4282	regulation of fungal-type cell wall biogenesis
KS08_06120	COG5290	Psort location Cytoplasmic, score
KS08_06125	COG5290	Psort location Cytoplasmic, score
KS08_06135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KS08_06180	COG2367	Beta-lactamase
KS08_06185	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KS08_06190	COG0477	Major facilitator Superfamily
KS08_06195	COG1846	Transcriptional regulator
KS08_06205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KS08_06205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KS08_06210	COG1447	Phosphotransferase system cellobiose-specific component IIA
KS08_06215	COG2723	6-phospho-beta-galactosidase activity
KS08_06220	COG1349	DNA-binding transcription factor activity
KS08_06240	COG1285	pathogenesis
KS08_06250	COG2205	protein histidine kinase activity
KS08_06260	COG3383	formate dehydrogenase (NAD+) activity
KS08_06265	COG2427	Protein of unknown function (DUF1641)
KS08_06270	COG2124	cytochrome p450
KS08_06275	COG1819	glycosyl
KS08_06285	COG1587	Uroporphyrinogen-III synthase
KS08_06290	COG0390	transport system, permease component
KS08_06295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KS08_06300	COG0697	spore germination
KS08_06305	COG4297	protein containing double-stranded beta helix domain
KS08_06315	COG1252	NADH dehydrogenase
KS08_06325	COG1609	Transcriptional regulator
KS08_06330	COG2721	sulfolactate sulfo-lyase activity
KS08_06335	COG0745	RESPONSE REGULATOR receiver
KS08_06340	COG2770	Histidine kinase
KS08_06340	COG2205	protein histidine kinase activity
KS08_06350	COG0730	response to heat
KS08_06355	COG2318	DinB family
KS08_06360	COG0457	Tetratricopeptide repeat
KS08_06370	COG1388	LysM domain
KS08_06370	COG3409	Peptidoglycan-binding domain 1 protein
KS08_06370	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_06380	COG4195	phage-related replication protein
KS08_06385	COG2856	Zn peptidase
KS08_06390	COG1396	sequence-specific DNA binding
KS08_06400	COG1522	sequence-specific DNA binding
KS08_06405	COG1484	DNA-dependent DNA replication
KS08_06425	COG1595	DNA-templated transcription, initiation
KS08_06430	COG3728	DNA packaging
KS08_06430	COG5484	DNA packaging
KS08_06435	COG1783	phage Terminase large subunit
KS08_06440	COG5518	Phage portal protein
KS08_06445	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KS08_06450	COG4653	Phage capsid family
KS08_06500	COG3953	SLT domain
KS08_06500	COG5412	phage tail tape measure protein
KS08_06500	COG3953	SLT domain
KS08_06500	COG5412	phage tail tape measure protein
KS08_06500	COG3953	SLT domain
KS08_06500	COG5412	phage tail tape measure protein
KS08_06505	COG1652	LysM domain
KS08_06510	COG4193	domain, Protein
KS08_06520	COG3628	GPW Gp25 family protein
KS08_06525	COG3299	homolog of phage Mu protein gp47
KS08_06530	COG3778	Protein conserved in bacteria
KS08_06570	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_06570	COG3409	Peptidoglycan-binding domain 1 protein
KS08_06585	COG0306	phosphate transporter
KS08_06590	COG1392	Phosphate transport regulator
KS08_06595	COG0531	amino acid
KS08_06600	COG0346	lactoylglutathione lyase activity
KS08_06605	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KS08_06610	COG0463	Glycosyl transferase, family 2
KS08_06615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS08_06620	COG0477	Major facilitator Superfamily
KS08_06625	COG2362	D-Aminopeptidase
KS08_06630	COG0601	transmembrane transport
KS08_06635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS08_06640	COG0444	Belongs to the ABC transporter superfamily
KS08_06645	COG4166	transmembrane transport
KS08_06650	COG1619	proteins homologs of microcin C7 resistance protein MccF
KS08_06655	COG4948	Mandelate Racemase Muconate Lactonizing
KS08_06660	COG0791	NLP P60 protein
KS08_06665	COG4608	Belongs to the ABC transporter superfamily
KS08_06670	COG2706	6-phosphogluconolactonase activity
KS08_06675	COG1834	amidinotransferase
KS08_06680	COG1607	acyl-coa hydrolase
KS08_06685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS08_06690	COG2076	Multidrug Resistance protein
KS08_06695	COG2076	Multidrug Resistance protein
KS08_06705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KS08_06715	COG1764	response to oxidative stress
KS08_06720	COG1846	Transcriptional regulator
KS08_06725	COG1764	response to oxidative stress
KS08_06740	COG0463	Glycosyl transferase, family 2
KS08_06740	COG0457	Tetratricopeptide repeat
KS08_06755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KS08_06765	COG1404	Belongs to the peptidase S8 family
KS08_06770	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_06775	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KS08_06780	COG1122	ATPase activity
KS08_06785	COG4721	ABC-type cobalt transport system, permease component
KS08_06790	COG3858	chitin binding
KS08_06790	COG1388	LysM domain
KS08_06805	COG2239	Acts as a magnesium transporter
KS08_06810	COG0789	Transcriptional regulator
KS08_06825	COG1846	Transcriptional regulator
KS08_06830	COG0726	polysaccharide deacetylase
KS08_06835	COG3285	dna ligase
KS08_06835	COG1793	dna ligase
KS08_06840	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KS08_06845	COG3300	MHYT domain
KS08_06845	COG5001	Diguanylate cyclase
KS08_06850	COG0586	Pfam SNARE associated Golgi protein
KS08_06855	COG0861	Integral membrane protein TerC family
KS08_06860	COG1191	sigma factor activity
KS08_06885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KS08_06905	COG3594	Acyltransferase
KS08_06910	COG5002	protein histidine kinase activity
KS08_06915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KS08_06930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KS08_06935	COG0436	Aminotransferase
KS08_06965	COG3852	Histidine kinase
KS08_06970	COG1846	Transcriptional regulator
KS08_06975	COG1360	Flagellar Motor Protein
KS08_06980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KS08_06985	COG0542	response to heat
KS08_06990	COG3949	Membrane
KS08_07005	COG0720	synthase
KS08_07010	COG0602	queuosine metabolic process
KS08_07025	COG4873	Protein conserved in bacteria
KS08_07035	COG3773	Cell wall hydrolase
KS08_07040	COG2244	polysaccharide biosynthetic process
KS08_07045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_07050	COG2217	Heavy metal translocating P-type atpase
KS08_07055	COG0006	proline dipeptidase activity
KS08_07065	COG1609	Transcriptional regulator
KS08_07070	COG3711	transcriptional antiterminator
KS08_07075	COG2190	(PTS) system
KS08_07075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_07075	COG1263	PTS System
KS08_07080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_07085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KS08_07095	COG1533	DNA photolyase activity
KS08_07100	COG0840	transmembrane signaling receptor activity
KS08_07105	COG2084	Dehydrogenase
KS08_07115	COG2340	Cysteine-rich secretory protein family
KS08_07120	COG0768	penicillin binding
KS08_07125	COG4191	Histidine kinase
KS08_07130	COG0436	Aminotransferase
KS08_07140	COG0784	Response regulator, receiver
KS08_07140	COG0835	chemotaxis
KS08_07150	COG2814	Major facilitator Superfamily
KS08_07155	COG1376	ErfK ybiS ycfS ynhG family protein
KS08_07160	COG1408	metallophosphoesterase
KS08_07165	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_07175	COG2200	EAL domain
KS08_07180	COG4703	Protein of unknown function (DUF1797)
KS08_07185	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KS08_07195	COG0517	IMP dehydrogenase activity
KS08_07200	COG0583	DNA-binding transcription factor activity
KS08_07205	COG0716	FMN binding
KS08_07215	COG0716	FMN binding
KS08_07235	COG0668	transmembrane transport
KS08_07245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_07265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KS08_07270	COG0303	'Molybdopterin
KS08_07275	COG1763	Mo-molybdopterin cofactor biosynthetic process
KS08_07280	COG0314	molybdopterin synthase activity
KS08_07285	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KS08_07295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KS08_07300	COG1136	(ABC) transporter
KS08_07305	COG0577	efflux transmembrane transporter activity
KS08_07310	COG1349	DNA-binding transcription factor activity
KS08_07315	COG1105	Belongs to the carbohydrate kinase PfkB family
KS08_07320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS08_07320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS08_07320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_07325	COG0681	Belongs to the peptidase S26 family
KS08_07335	COG0488	(ABC) transporter
KS08_07340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KS08_07345	COG2309	aminopeptidase activity
KS08_07355	COG1077	Cell shape determining protein MreB Mrl
KS08_07360	COG2002	toxin-antitoxin pair type II binding
KS08_07365	COG3852	Histidine kinase
KS08_07370	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KS08_07370	COG2105	PFAM AIG2 family protein
KS08_07375	COG0569	domain protein
KS08_07385	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KS08_07395	COG0561	phosphatase activity
KS08_07400	COG0242	peptide deformylase activity
KS08_07410	COG0497	DNA recombination
KS08_07415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KS08_07420	COG0022	dehydrogenase e1 component
KS08_07425	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS08_07430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KS08_07435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_07445	COG1982	Orn Lys Arg decarboxylase major
KS08_07465	COG0483	inositol monophosphate 1-phosphatase activity
KS08_07475	COG3227	Zinc metalloprotease (Elastase)
KS08_07510	COG4896	Protein conserved in bacteria
KS08_07520	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KS08_07525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KS08_07530	COG2066	Belongs to the glutaminase family
KS08_07540	COG0772	Belongs to the SEDS family
KS08_07545	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KS08_07560	COG2010	Cytochrome c
KS08_07560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KS08_07565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KS08_07570	COG1845	cytochrome c oxidase, subunit III
KS08_07575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KS08_07580	COG3336	cytochrome c oxidase
KS08_07590	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KS08_07595	COG2340	Cysteine-rich secretory protein family
KS08_07610	COG3679	Belongs to the UPF0342 family
KS08_07620	COG0742	ribosomal rna small subunit methyltransferase
KS08_07630	COG3314	Sporulation integral membrane protein YlbJ
KS08_07635	COG1752	Esterase of the alpha-beta hydrolase superfamily
KS08_07640	COG3480	Lon protease (S16) C-terminal proteolytic domain
KS08_07650	COG1399	metal-binding, possibly nucleic acid-binding protein
KS08_07655	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KS08_07670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KS08_07690	COG4839	cell division protein FtsL
KS08_07700	COG0768	penicillin binding
KS08_07725	COG0772	Belongs to the SEDS family
KS08_07740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KS08_07750	COG0849	cell division
KS08_07755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KS08_07760	COG4412	M6 family metalloprotease domain protein
KS08_07760	COG1404	Belongs to the peptidase S8 family
KS08_07770	COG1191	sigma factor activity
KS08_07775	COG1191	sigma factor activity
KS08_07780	COG1119	ATPase activity
KS08_07785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS08_07790	COG1873	PFAM PRC-barrel domain
KS08_07800	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KS08_07810	COG0762	integral membrane protein
KS08_07815	COG2302	S4 RNA-binding domain
KS08_07820	COG3599	regulation of cell shape
KS08_07830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KS08_07835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KS08_07845	COG0564	pseudouridine synthase activity
KS08_07855	COG2233	PERMEase
KS08_07865	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KS08_07870	COG0505	Belongs to the CarA family
KS08_07875	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KS08_07890	COG0284	orotidine-5'-phosphate decarboxylase activity
KS08_07895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KS08_07910	COG0306	phosphate transporter
KS08_07925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KS08_07930	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KS08_07935	COG1648	precorrin-2 dehydrogenase activity
KS08_07950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KS08_07955	COG1561	YicC-like family, N-terminal region
KS08_07960	COG2052	Domain of unknown function (DUF370)
KS08_07965	COG0194	GDP metabolic process
KS08_07975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KS08_07980	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KS08_07985	COG0242	peptide deformylase activity
KS08_07995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KS08_07995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KS08_08005	COG0631	protein serine/threonine phosphatase activity
KS08_08010	COG0515	serine threonine protein kinase
KS08_08010	COG2815	serine threonine protein kinase
KS08_08020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KS08_08025	COG1564	THIamine pyrophosphokinase
KS08_08040	COG1302	Protein conserved in bacteria
KS08_08045	COG1461	Dihydroxyacetone kinase
KS08_08050	COG1760	l-serine dehydratase
KS08_08055	COG1760	l-serine dehydratase
KS08_08060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KS08_08075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KS08_08080	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_08085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_08095	COG1196	nuclear chromosome segregation
KS08_08100	COG0552	protein localization to endoplasmic reticulum
KS08_08110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KS08_08120	COG1837	Belongs to the UPF0109 family
KS08_08145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KS08_08160	COG2257	FlhB HrpN YscU SpaS Family
KS08_08170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KS08_08175	COG0758	DNA mediated transformation
KS08_08180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KS08_08190	COG4974	Belongs to the 'phage' integrase family
KS08_08215	COG1558	bacterial-type flagellum-dependent cell motility
KS08_08220	COG1677	Flagellar hook-basal body complex protein FliE
KS08_08225	COG1766	The M ring may be actively involved in energy transduction
KS08_08230	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KS08_08235	COG1317	bacterial-type flagellum organization
KS08_08240	COG1157	protein secretion by the type III secretion system
KS08_08245	COG2882	bacterial-type flagellum organization
KS08_08250	COG3334	PFAM MgtE intracellular
KS08_08255	COG3144	bacterial-type flagellum assembly
KS08_08260	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KS08_08265	COG4786	Flagellar basal body rod
KS08_08270	COG1582	Flagellar protein (FlbD)
KS08_08275	COG1580	Controls the rotational direction of flagella during chemotaxis
KS08_08280	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KS08_08285	COG1776	CheC inhibitor of MCP methylation
KS08_08285	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KS08_08290	COG2201	protein-glutamate methylesterase activity
KS08_08295	COG3190	flagellar
KS08_08300	COG1338	Plays a role in the flagellum-specific transport system
KS08_08305	COG1987	bacterial-type flagellum assembly
KS08_08310	COG1684	flagellar biosynthetic protein fliR
KS08_08315	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KS08_08320	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KS08_08325	COG1419	protein localization to endoplasmic reticulum
KS08_08330	COG0455	bacterial-type flagellum organization
KS08_08335	COG2201	protein-glutamate methylesterase activity
KS08_08340	COG0643	Histidine kinase
KS08_08340	COG2198	Histidine kinase
KS08_08345	COG0835	chemotaxis
KS08_08350	COG1776	CheC inhibitor of MCP methylation
KS08_08360	COG1191	sigma factor activity
KS08_08390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KS08_08395	COG4589	Belongs to the CDS family
KS08_08405	COG0750	zinc metalloprotease
KS08_08415	COG2176	DNA-directed DNA polymerase activity
KS08_08425	COG0195	Participates in both transcription termination and antitermination
KS08_08430	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KS08_08435	COG1358	cellular component organization or biogenesis
KS08_08445	COG1550	Protein conserved in bacteria
KS08_08460	COG0196	riboflavin kinase activity
KS08_08475	COG0726	polysaccharide deacetylase
KS08_08480	COG0612	Peptidase, M16
KS08_08485	COG1873	PFAM PRC-barrel domain
KS08_08490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KS08_08495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KS08_08500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KS08_08505	COG0527	aspartate kinase activity
KS08_08515	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KS08_08520	COG0740	serine-type endopeptidase activity
KS08_08530	COG1674	ftsk spoiiie
KS08_08530	COG4980	gas vesicle protein
KS08_08535	COG2188	Transcriptional regulator
KS08_08540	COG2814	Major facilitator Superfamily
KS08_08545	COG1846	Transcriptional regulator
KS08_08550	COG2409	Drug exporters of the RND superfamily
KS08_08550	COG1033	growth of symbiont in host cell
KS08_08555	COG0612	Peptidase, M16
KS08_08560	COG0612	Peptidase, M16
KS08_08565	COG0300	oxidoreductase activity
KS08_08580	COG1426	Protein conserved in bacteria
KS08_08585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KS08_08600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KS08_08610	COG1692	metallophosphoesterase
KS08_08615	COG2359	stage V sporulation protein S
KS08_08635	COG4550	Control of competence regulator ComK, YlbF/YmcA
KS08_08675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_08680	COG3425	synthase
KS08_08685	COG1024	Enoyl-CoA hydratase
KS08_08690	COG1024	Enoyl-CoA hydratase
KS08_08695	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_08695	COG3321	synthase
KS08_08695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_08695	COG0300	oxidoreductase activity
KS08_08695	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_08700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_08700	COG4221	oxidoreductase activity
KS08_08700	COG0300	oxidoreductase activity
KS08_08700	COG3321	synthase
KS08_08705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_08705	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_08705	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_08705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_08705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS08_08705	COG3321	synthase
KS08_08705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS08_08705	COG3321	synthase
KS08_08705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_08705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_08710	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_08710	COG3321	synthase
KS08_08710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_08710	COG4221	oxidoreductase activity
KS08_08715	COG3321	synthase
KS08_08715	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KS08_08715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_08715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KS08_08720	COG2124	cytochrome p450
KS08_08725	COG3209	COG3209 Rhs family protein
KS08_08730	COG3619	membrane
KS08_08740	COG1404	Belongs to the peptidase S8 family
KS08_08750	COG4195	phage-related replication protein
KS08_08755	COG1764	response to oxidative stress
KS08_08765	COG2076	Multidrug Resistance protein
KS08_08805	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KS08_08810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KS08_08815	COG4112	unkown
KS08_08830	COG0464	growth
KS08_08835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KS08_08840	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KS08_08845	COG0789	Transcriptional regulator
KS08_08850	COG0174	glutamine synthetase
KS08_08875	COG0726	polysaccharide deacetylase
KS08_08880	COG2124	cytochrome p450
KS08_08885	COG2211	Major facilitator Superfamily
KS08_08890	COG3507	Belongs to the glycosyl hydrolase 43 family
KS08_08905	COG1070	Carbohydrate kinase
KS08_08915	COG3848	Pyruvate phosphate dikinase
KS08_08915	COG0574	Belongs to the PEP-utilizing enzyme family
KS08_08925	COG1063	alcohol dehydrogenase
KS08_08935	COG0457	Tetratricopeptide repeat
KS08_08950	COG2318	DinB family
KS08_08955	COG1064	alcohol dehydrogenase
KS08_08980	COG0456	acetyltransferase
KS08_09015	COG3397	chitin binding
KS08_09030	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_09035	COG2314	TM2 domain
KS08_09040	COG0756	dUTP diphosphatase activity
KS08_09050	COG4195	phage-related replication protein
KS08_09080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KS08_09090	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KS08_09110	COG0785	Cytochrome C biogenesis protein
KS08_09115	COG2201	protein-glutamate methylesterase activity
KS08_09120	COG4846	Membrane protein involved in cytochrome C biogenesis
KS08_09130	COG0071	Belongs to the small heat shock protein (HSP20) family
KS08_09145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KS08_09150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_09170	COG0824	Thioesterase
KS08_09180	COG4841	protein insertion into membrane
KS08_09190	COG1832	CoA-binding protein
KS08_09195	COG0187	DNA topoisomerase II activity
KS08_09200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KS08_09215	COG1115	amino acid carrier protein
KS08_09245	COG2205	protein histidine kinase activity
KS08_09250	COG0745	RESPONSE REGULATOR receiver
KS08_09260	COG3507	Belongs to the glycosyl hydrolase 43 family
KS08_09285	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_09290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KS08_09295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KS08_09300	COG2124	cytochrome p450
KS08_09305	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KS08_09320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KS08_09330	COG2246	polysaccharide biosynthetic process
KS08_09335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KS08_09340	COG0586	Pfam SNARE associated Golgi protein
KS08_09345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KS08_09350	COG1024	Enoyl-CoA hydratase
KS08_09355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KS08_09360	COG0511	ligase activity, forming carbon-carbon bonds
KS08_09365	COG0439	Biotin carboxylase
KS08_09370	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_09375	COG1960	acyl-CoA dehydrogenase activity
KS08_09380	COG1649	PFAM Uncharacterised BCR, COG1649
KS08_09390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_09390	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KS08_09395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_09400	COG2027	D-alanyl-D-alanine carboxypeptidase
KS08_09405	COG2017	converts alpha-aldose to the beta-anomer
KS08_09410	COG0534	Mate efflux family protein
KS08_09425	COG0582	viral genome integration into host DNA
KS08_09430	COG0166	Belongs to the GPI family
KS08_09435	COG0405	Gamma-glutamyltransferase
KS08_09440	COG2814	Major facilitator Superfamily
KS08_09445	COG0640	Transcriptional regulator
KS08_09450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KS08_09460	COG0604	alcohol dehydrogenase
KS08_09470	COG0493	'glutamate synthase
KS08_09475	COG0069	glutamate synthase activity
KS08_09475	COG0067	glutamate synthase
KS08_09475	COG0070	glutamate synthase
KS08_09480	COG0583	DNA-binding transcription factor activity
KS08_09485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KS08_09500	COG0300	oxidoreductase activity
KS08_09505	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KS08_09515	COG2814	Major facilitator Superfamily
KS08_09520	COG1070	Carbohydrate kinase
KS08_09525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KS08_09530	COG0243	molybdopterin cofactor binding
KS08_09560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS08_09565	COG2207	Transcriptional regulator
KS08_09565	COG0662	Cupin 2, conserved barrel domain protein
KS08_09570	COG1309	transcriptional regulator
KS08_09575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_09585	COG0640	Transcriptional regulator
KS08_09590	COG0741	lytic transglycosylase activity
KS08_09595	COG2322	membrane
KS08_09610	COG1619	proteins homologs of microcin C7 resistance protein MccF
KS08_09620	COG1388	LysM domain
KS08_09620	COG3584	3D domain protein
KS08_09625	COG0514	ATP-dependent DNA helicase (RecQ)
KS08_09635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KS08_09640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KS08_09655	COG0071	Belongs to the small heat shock protein (HSP20) family
KS08_09685	COG1012	belongs to the aldehyde dehydrogenase family
KS08_09690	COG1657	PFAM Prenyltransferase squalene oxidase
KS08_09695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KS08_09700	COG0733	neurotransmitter:sodium symporter activity
KS08_09705	COG0385	Bile acid
KS08_09710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_09715	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS08_09725	COG4548	von Willebrand factor, type A
KS08_09730	COG0714	Associated with various cellular activities
KS08_09735	COG2032	superoxide dismutase activity
KS08_09740	COG1388	LysM domain
KS08_09740	COG0791	NLP P60 protein
KS08_09745	COG1819	glycosyl
KS08_09750	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KS08_09755	COG0534	Mate efflux family protein
KS08_09760	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_09765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KS08_09770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KS08_09780	COG2962	Rard protein
KS08_09795	COG1942	4-Oxalocrotonate Tautomerase
KS08_09805	COG1733	regulation of RNA biosynthetic process
KS08_09810	COG0778	Nitroreductase
KS08_09815	COG0400	carboxylic ester hydrolase activity
KS08_09820	COG0346	lactoylglutathione lyase activity
KS08_09830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS08_09840	COG2723	6-phospho-beta-galactosidase activity
KS08_09845	COG2188	Transcriptional regulator
KS08_09850	COG0793	Belongs to the peptidase S41A family
KS08_09850	COG3409	Peptidoglycan-binding domain 1 protein
KS08_09855	COG2226	methyltransferase
KS08_09865	COG1876	peptidase activity
KS08_09885	COG0671	phosphoesterase, PA-phosphatase related
KS08_09905	COG0346	lactoylglutathione lyase activity
KS08_09920	COG1509	lysine 2,3-aminomutase activity
KS08_09925	COG0456	acetyltransferase
KS08_09930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS08_09935	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KS08_09940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KS08_09945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KS08_09955	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KS08_09965	COG0456	acetyltransferase
KS08_09970	COG0463	Glycosyl transferase, family 2
KS08_09985	COG4641	Protein conserved in bacteria
KS08_10025	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KS08_10030	COG1086	Polysaccharide biosynthesis protein
KS08_10045	COG1846	Transcriptional regulator
KS08_10050	COG4698	Protein conserved in bacteria
KS08_10055	COG2755	lipolytic protein G-D-S-L family
KS08_10060	COG1999	signal sequence binding
KS08_10070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KS08_10075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KS08_10080	COG1272	protein, Hemolysin III
KS08_10085	COG0204	Acyl-transferase
KS08_10090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KS08_10095	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KS08_10105	COG2136	Putative SAM-dependent methyltransferase
KS08_10105	COG2521	methyltransferase
KS08_10120	COG1413	lyase activity
KS08_10125	COG1418	mRNA catabolic process
KS08_10130	COG0386	Belongs to the glutathione peroxidase family
KS08_10140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KS08_10145	COG1278	Cold shock
KS08_10165	COG0328	RNA-DNA hybrid ribonuclease activity
KS08_10170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KS08_10175	COG0328	RNA-DNA hybrid ribonuclease activity
KS08_10185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KS08_10200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KS08_10205	COG1755	Isoprenylcysteine carboxyl methyltransferase
KS08_10210	COG3424	synthase
KS08_10235	COG3331	DNA recombination
KS08_10270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KS08_10275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KS08_10300	COG0756	dUTP diphosphatase activity
KS08_10350	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KS08_10350	COG1372	Participates in initiation and elongation during chromosome replication
KS08_10360	COG1780	Probably involved in ribonucleotide reductase function
KS08_10440	COG0270	DNA (cytosine-5-)-methyltransferase activity
KS08_10450	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KS08_10455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KS08_10475	COG3584	3D domain protein
KS08_10485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KS08_10525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KS08_10530	COG3420	alginic acid biosynthetic process
KS08_10530	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_10535	COG4195	phage-related replication protein
KS08_10570	COG2135	peptidase activity
KS08_10575	COG1793	dna ligase
KS08_10700	COG0582	viral genome integration into host DNA
KS08_10800	COG3655	Transcriptional regulator
KS08_10830	COG3646	Phage regulatory protein
KS08_10830	COG3645	SOS response
KS08_10835	COG0210	DNA helicase
KS08_10895	COG0776	regulation of translation
KS08_11015	COG0582	viral genome integration into host DNA
KS08_11030	COG0515	serine threonine protein kinase
KS08_11030	COG2815	serine threonine protein kinase
KS08_11060	COG2433	Pfam Transposase IS66
KS08_11075	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_11080	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_11080	COG3409	Peptidoglycan-binding domain 1 protein
KS08_11110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KS08_11140	COG5444	nuclease activity
KS08_11150	COG4282	regulation of fungal-type cell wall biogenesis
KS08_11155	COG1525	nuclease
KS08_11165	COG2233	PERMEase
KS08_11175	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KS08_11180	COG1199	ATP-dependent helicase activity
KS08_11195	COG0116	Belongs to the methyltransferase superfamily
KS08_11215	COG3359	exonuclease
KS08_11220	COG1205	dead DEAH box helicase
KS08_11220	COG1111	helicase
KS08_11225	COG2190	(PTS) system
KS08_11270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS08_11270	COG4499	WXG100 protein secretion system (Wss), protein YukC
KS08_11280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KS08_11285	COG3935	DnaD domain protein
KS08_11295	COG0436	Aminotransferase
KS08_11300	COG5353	protein conserved in bacteria
KS08_11310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KS08_11310	COG1199	ATP-dependent helicase activity
KS08_11340	COG0438	transferase activity, transferring glycosyl groups
KS08_11345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KS08_11360	COG1694	Mazg nucleotide pyrophosphohydrolase
KS08_11365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_11370	COG2140	Oxalate decarboxylase
KS08_11380	COG4347	Protein of unknown function (DUF1405)
KS08_11385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KS08_11385	COG2010	Cytochrome c
KS08_11390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KS08_11395	COG0723	plastoquinol--plastocyanin reductase activity
KS08_11410	COG0457	Tetratricopeptide repeat
KS08_11420	COG0287	Prephenate dehydrogenase
KS08_11455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KS08_11460	COG4401	Chorismate mutase type I
KS08_11475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KS08_11480	COG0105	UTP biosynthetic process
KS08_11485	COG0142	geranyltranstransferase activity
KS08_11495	COG0142	geranyltranstransferase activity
KS08_11510	COG0776	regulation of translation
KS08_11515	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KS08_11555	COG0539	negative regulation of cytoplasmic translation
KS08_11570	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KS08_11575	COG2959	enzyme of heme biosynthesis
KS08_11580	COG3773	Cell wall hydrolase
KS08_11580	COG3409	Peptidoglycan-binding domain 1 protein
KS08_11585	COG2339	peptidase activity
KS08_11590	COG0492	ferredoxin-NADP+ reductase activity
KS08_11595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KS08_11600	COG4862	establishment of competence for transformation
KS08_11605	COG1408	metallophosphoesterase
KS08_11615	COG1388	LysM domain
KS08_11620	COG1266	CAAX protease self-immunity
KS08_11625	COG0514	ATP-dependent DNA helicase (RecQ)
KS08_11630	COG4955	Helix-turn-helix domain
KS08_11635	COG1141	Ferredoxin
KS08_11640	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KS08_11645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KS08_11655	COG1595	DNA-templated transcription, initiation
KS08_11660	COG5002	protein histidine kinase activity
KS08_11665	COG0745	RESPONSE REGULATOR receiver
KS08_11670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KS08_11675	COG1333	cytochrome c biogenesis protein
KS08_11680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_11685	COG1187	pseudouridine synthase activity
KS08_11690	COG0700	Nucleoside recognition
KS08_11695	COG2715	membrane protein required for spore maturation
KS08_11700	COG1686	Belongs to the peptidase S11 family
KS08_11720	COG1547	Domain of unknown function (DUF309)
KS08_11725	COG0456	acetyltransferase
KS08_11730	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KS08_11735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KS08_11735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KS08_11740	COG0307	riboflavin synthase, alpha
KS08_11745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KS08_11745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KS08_11755	COG0681	Belongs to the peptidase S26 family
KS08_11765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KS08_11770	COG4086	secreted protein
KS08_11775	COG0019	diaminopimelate decarboxylase activity
KS08_11780	COG0697	spore germination
KS08_11795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KS08_11815	COG1191	sigma factor activity
KS08_11825	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_11830	COG1686	Belongs to the peptidase S11 family
KS08_11835	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KS08_11845	COG4974	Belongs to the 'phage' integrase family
KS08_11855	COG0735	belongs to the Fur family
KS08_11860	COG1300	Membrane
KS08_11875	COG0281	malic enzyme
KS08_11880	COG1757	Na H antiporter
KS08_11885	COG1027	Aspartate ammonia-lyase
KS08_11890	COG0252	asparaginase activity
KS08_11895	COG1396	sequence-specific DNA binding
KS08_11900	COG1379	DNA repair
KS08_11905	COG0494	nUDIX hydrolase
KS08_11915	COG0667	Aldo Keto reductase
KS08_11925	COG1073	alpha beta
KS08_11935	COG4918	Iron-sulphur cluster biosynthesis
KS08_11940	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KS08_11940	COG0456	acetyltransferase
KS08_11945	COG0456	acetyltransferase
KS08_11950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KS08_11965	COG0628	permease
KS08_11975	COG3048	D-serine ammonia-lyase activity
KS08_11980	COG0300	oxidoreductase activity
KS08_11985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_11990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KS08_12015	COG0596	Alpha beta hydrolase
KS08_12030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KS08_12035	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KS08_12050	COG0706	membrane insertase activity
KS08_12055	COG2195	Cleaves the N-terminal amino acid of tripeptides
KS08_12060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KS08_12065	COG0346	lactoylglutathione lyase activity
KS08_12075	COG1376	ErfK ybiS ycfS ynhG family protein
KS08_12080	COG4129	membrane
KS08_12085	COG1126	abc transporter atp-binding protein
KS08_12090	COG0765	amino acid transport
KS08_12095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_12105	COG1597	lipid kinase activity
KS08_12110	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS08_12115	COG0022	dehydrogenase e1 component
KS08_12120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KS08_12125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KS08_12130	COG3426	butyrate kinase activity
KS08_12135	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KS08_12140	COG0280	phosphate acetyltransferase
KS08_12145	COG3290	protein histidine kinase activity
KS08_12145	COG3829	transcription factor binding
KS08_12155	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KS08_12160	COG2079	MmgE PrpD family protein
KS08_12165	COG0372	Belongs to the citrate synthase family
KS08_12170	COG1960	acyl-CoA dehydrogenase activity
KS08_12175	COG1250	3-hydroxyacyl-CoA dehydrogenase
KS08_12180	COG0183	Belongs to the thiolase family
KS08_12185	COG0584	glycerophosphoryl diester phosphodiesterase
KS08_12190	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS08_12215	COG1902	pentaerythritol trinitrate reductase activity
KS08_12230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KS08_12235	COG0745	RESPONSE REGULATOR receiver
KS08_12245	COG0750	zinc metalloprotease
KS08_12250	COG0497	DNA recombination
KS08_12260	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KS08_12270	COG0142	geranyltranstransferase activity
KS08_12280	COG1570	exodeoxyribonuclease VII activity
KS08_12295	COG1302	Protein conserved in bacteria
KS08_12300	COG0439	Biotin carboxylase
KS08_12305	COG0511	ligase activity, forming carbon-carbon bonds
KS08_12345	COG3854	ATPases associated with a variety of cellular activities
KS08_12360	COG0006	proline dipeptidase activity
KS08_12370	COG3872	metal-dependent enzyme
KS08_12380	COG1752	Esterase of the alpha-beta hydrolase superfamily
KS08_12395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KS08_12415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KS08_12430	COG1396	sequence-specific DNA binding
KS08_12440	COG0681	Belongs to the peptidase S26 family
KS08_12465	COG4940	Competence protein ComGF
KS08_12475	COG4970	Tfp pilus assembly protein FimT
KS08_12480	COG4537	Required for transformation and DNA binding
KS08_12485	COG1459	type II secretion system
KS08_12490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KS08_12495	COG0598	Magnesium transport protein CorA
KS08_12500	COG1253	flavin adenine dinucleotide binding
KS08_12505	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_12515	COG1393	Belongs to the ArsC family
KS08_12525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_12535	COG0011	TIGRFAM Protein of
KS08_12545	COG2866	Carboxypeptidase
KS08_12550	COG1940	carbohydrate kinase activity
KS08_12555	COG4483	Protein conserved in bacteria
KS08_12560	COG1757	Na H antiporter
KS08_12570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KS08_12575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KS08_12585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KS08_12590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KS08_12595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KS08_12600	COG0581	inorganic phosphate transmembrane transporter activity
KS08_12605	COG0573	inorganic phosphate transmembrane transporter activity
KS08_12610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KS08_12620	COG0477	Major facilitator Superfamily
KS08_12625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KS08_12630	COG2839	Protein conserved in bacteria
KS08_12635	COG5521	maltodextrose utilization protein MalA
KS08_12640	COG1388	LysM domain
KS08_12650	COG4709	membrane
KS08_12655	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KS08_12660	COG0735	belongs to the Fur family
KS08_12665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_12680	COG0513	Belongs to the DEAD box helicase family
KS08_12695	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KS08_12700	COG2384	SAM-dependent methyltransferase
KS08_12705	COG2010	Cytochrome c
KS08_12710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KS08_12715	COG0358	DNA primase activity
KS08_12730	COG0517	IMP dehydrogenase activity
KS08_12735	COG0751	glycine-tRNA ligase activity
KS08_12755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KS08_12760	COG0295	cytidine deaminase activity
KS08_12765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KS08_12775	COG1480	7TM receptor with intracellular HD hydrolase
KS08_12780	COG1702	phosphate starvation-inducible protein PhoH
KS08_12785	COG0561	phosphatase activity
KS08_12800	COG4864	UPF0365 protein
KS08_12805	COG1030	water channel activity
KS08_12810	COG1610	YqeY-like protein
KS08_12815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KS08_12820	COG1283	sodium-dependent phosphate transmembrane transporter activity
KS08_12825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KS08_12830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KS08_12860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KS08_12875	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS08_12890	COG1466	dna polymerase III delta subunit
KS08_12900	COG0658	competence protein
KS08_12900	COG2333	competence protein COMEC
KS08_12905	COG2131	deaminase
KS08_12910	COG1596	polysaccharide export
KS08_12910	COG1555	photosystem II stabilization
KS08_12915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KS08_12920	COG2226	methyltransferase
KS08_12925	COG0799	negative regulation of ribosome biogenesis
KS08_12930	COG1713	HD superfamily hydrolase involved in NAD metabolism
KS08_12940	COG1534	Rna-binding protein
KS08_12945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KS08_12950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KS08_12955	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KS08_12965	COG2755	lipolytic protein G-D-S-L family
KS08_12970	COG0726	polysaccharide deacetylase
KS08_12975	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_12975	COG3409	Peptidoglycan-binding domain 1 protein
KS08_12980	COG0398	Pfam SNARE associated Golgi protein
KS08_13020	COG0563	adenylate kinase activity
KS08_13030	COG2814	Major facilitator Superfamily
KS08_13035	COG2318	DinB family
KS08_13040	COG0561	phosphatase activity
KS08_13045	COG0561	phosphatase activity
KS08_13055	COG1482	cell wall glycoprotein biosynthetic process
KS08_13060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_13060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS08_13060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS08_13065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_13065	COG3711	transcriptional antiterminator
KS08_13075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KS08_13080	COG0583	DNA-binding transcription factor activity
KS08_13085	COG2814	Major facilitator Superfamily
KS08_13090	COG2124	cytochrome p450
KS08_13090	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KS08_13095	COG1309	transcriptional regulator
KS08_13100	COG2226	methyltransferase
KS08_13110	COG2116	formate transmembrane transporter activity
KS08_13115	COG5609	conserved protein (DUF2294)
KS08_13120	COG3383	formate dehydrogenase (NAD+) activity
KS08_13125	COG2427	Protein of unknown function (DUF1641)
KS08_13135	COG0626	cystathionine gamma-synthase activity
KS08_13140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KS08_13165	COG0768	penicillin binding
KS08_13195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KS08_13210	COG4472	Bacterial protein of unknown function (DUF965)
KS08_13220	COG0628	permease
KS08_13225	COG1126	abc transporter atp-binding protein
KS08_13230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_13235	COG0765	amino acid transport
KS08_13240	COG0765	amino acid transport
KS08_13255	COG3881	PFAM PRC-barrel domain
KS08_13260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KS08_13265	COG0457	Tetratricopeptide repeat
KS08_13275	COG1104	cysteine desulfurase activity
KS08_13280	COG1959	2 iron, 2 sulfur cluster binding
KS08_13285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KS08_13290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KS08_13320	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS08_13320	COG4991	sh3 domain protein
KS08_13320	COG3103	Sh3 type 3 domain protein
KS08_13325	COG1490	D-aminoacyl-tRNA deacylase activity
KS08_13330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KS08_13340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KS08_13340	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KS08_13345	COG5416	Lipopolysaccharide assembly protein A domain
KS08_13350	COG0490	domain, Protein
KS08_13355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KS08_13355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KS08_13365	COG2244	polysaccharide biosynthetic process
KS08_13370	COG2323	membrane
KS08_13380	COG1862	Preprotein translocase
KS08_13420	COG1388	LysM domain
KS08_13430	COG0157	Belongs to the NadC ModD family
KS08_13435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KS08_13440	COG1104	cysteine desulfurase activity
KS08_13445	COG1827	regulation of RNA biosynthetic process
KS08_13450	COG0077	Prephenate dehydratase
KS08_13465	COG3290	protein histidine kinase activity
KS08_13470	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KS08_13475	COG2868	ribosomal protein
KS08_13485	COG1994	Peptidase M50
KS08_13490	COG0739	heme binding
KS08_13495	COG2894	cell division
KS08_13500	COG0850	regulation of cytokinetic process
KS08_13505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KS08_13510	COG1792	Involved in formation and maintenance of cell shape
KS08_13515	COG1077	Cell shape determining protein MreB Mrl
KS08_13535	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KS08_13540	COG0285	dihydrofolate synthase activity
KS08_13545	COG0525	valine-tRNA ligase activity
KS08_13555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KS08_13560	COG1388	LysM domain
KS08_13570	COG0113	porphobilinogen synthase activity
KS08_13575	COG1587	Uroporphyrinogen-III synthase
KS08_13585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KS08_13605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KS08_13610	COG1067	ATP-dependent peptidase activity
KS08_13610	COG0470	DNA polymerase III
KS08_13625	COG0457	Tetratricopeptide repeat
KS08_13625	COG1477	protein flavinylation
KS08_13640	COG0473	3-isopropylmalate dehydrogenase activity
KS08_13655	COG0440	acetolactate synthase activity
KS08_13660	COG0028	Belongs to the TPP enzyme family
KS08_13685	COG0622	Phosphoesterase
KS08_13690	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KS08_13700	COG5401	PFAM Sporulation and spore germination
KS08_13710	COG1846	Transcriptional regulator
KS08_13715	COG2197	response regulator
KS08_13720	COG0824	Thioesterase
KS08_13725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KS08_13730	COG1053	succinate dehydrogenase
KS08_13735	COG2009	succinate dehydrogenase
KS08_13745	COG1719	4-vinyl reductase, 4VR
KS08_13750	COG0527	aspartate kinase activity
KS08_13760	COG3118	belongs to the thioredoxin family
KS08_13765	COG3534	alpha-L-arabinofuranosidase
KS08_13770	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KS08_13775	COG2086	electron transfer activity
KS08_13780	COG1024	Enoyl-CoA hydratase
KS08_13785	COG1309	transcriptional regulator
KS08_13790	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_13800	COG3766	membrane
KS08_13810	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KS08_13810	COG1796	DNA polymerase
KS08_13815	COG1286	toxin biosynthetic process
KS08_13830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS08_13830	COG0072	phenylalanine-tRNA ligase activity
KS08_13835	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KS08_13840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KS08_13850	COG3835	regulator
KS08_13855	COG0277	FAD linked oxidase domain protein
KS08_13860	COG0247	lactate metabolic process
KS08_13865	COG1966	Carbon starvation protein
KS08_13870	COG3534	alpha-L-arabinofuranosidase
KS08_13875	COG0395	ABC-type sugar transport system, permease component
KS08_13880	COG1175	transmembrane transport
KS08_13885	COG1653	transport
KS08_13895	COG0647	UMP catabolic process
KS08_13900	COG0235	Class ii aldolase
KS08_13905	COG1069	ribulokinase activity
KS08_13910	COG2160	L-arabinose isomerase activity
KS08_13915	COG3507	Belongs to the glycosyl hydrolase 43 family
KS08_13920	COG1363	Peptidase, m42
KS08_13930	COG3326	Membrane
KS08_13935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KS08_13945	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KS08_13950	COG1346	cytolysis
KS08_13955	COG1380	Effector of murein hydrolase LrgA
KS08_13960	COG3279	Response regulator of the LytR AlgR family
KS08_13965	COG3275	phosphorelay sensor kinase activity
KS08_13985	COG0398	Pfam SNARE associated Golgi protein
KS08_13990	COG1484	DNA-dependent DNA replication
KS08_13995	COG3611	Membrane attachment protein
KS08_14010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KS08_14015	COG1733	regulation of RNA biosynthetic process
KS08_14020	COG2814	Major facilitator Superfamily
KS08_14025	COG0656	L-ascorbic acid biosynthetic process
KS08_14030	COG0237	dephospho-CoA kinase activity
KS08_14035	COG1971	Probably functions as a manganese efflux pump
KS08_14040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KS08_14045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KS08_14045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KS08_14050	COG5002	protein histidine kinase activity
KS08_14055	COG0745	RESPONSE REGULATOR receiver
KS08_14065	COG0538	isocitrate dehydrogenase activity
KS08_14070	COG0372	Belongs to the citrate synthase family
KS08_14080	COG0628	permease
KS08_14085	COG3030	protein affecting phage T7 exclusion by the F plasmid
KS08_14090	COG0469	pyruvate kinase activity
KS08_14115	COG0281	malic enzyme
KS08_14120	COG0587	DNA-directed DNA polymerase activity
KS08_14140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KS08_14150	COG4109	DRTGG domain
KS08_14160	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_14180	COG0521	Mo-molybdopterin cofactor biosynthetic process
KS08_14190	COG0827	DNA restriction-modification system
KS08_14195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KS08_14200	COG3874	Sporulation protein YtfJ
KS08_14210	COG1714	RDD family
KS08_14215	COG0616	signal peptide processing
KS08_14220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KS08_14225	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KS08_14230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KS08_14245	COG1104	cysteine desulfurase activity
KS08_14250	COG1114	Component of the transport system for branched-chain amino acids
KS08_14260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KS08_14265	COG1309	transcriptional regulator
KS08_14270	COG1956	GAF domain-containing protein
KS08_14275	COG2199	diguanylate cyclase activity
KS08_14275	COG2203	Gaf domain
KS08_14285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KS08_14285	COG1017	nitric oxide dioxygenase activity
KS08_14295	COG0693	protein deglycase activity
KS08_14310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS08_14315	COG1378	Sugar-specific transcriptional regulator TrmB
KS08_14320	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KS08_14335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KS08_14340	COG0454	-acetyltransferase
KS08_14345	COG0517	IMP dehydrogenase activity
KS08_14350	COG0123	including yeast histone deacetylase and acetoin utilization protein
KS08_14355	COG1360	Flagellar Motor Protein
KS08_14360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KS08_14365	COG1609	Transcriptional regulator
KS08_14370	COG1605	Chorismate mutase
KS08_14370	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KS08_14375	COG3118	belongs to the thioredoxin family
KS08_14380	COG4980	gas vesicle protein
KS08_14385	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KS08_14395	COG1674	ftsk spoiiie
KS08_14400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS08_14410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_14420	COG1363	Peptidase, m42
KS08_14425	COG5584	Small secreted protein
KS08_14430	COG0281	malic enzyme
KS08_14435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_14450	COG0510	thiamine kinase activity
KS08_14455	COG1597	lipid kinase activity
KS08_14465	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KS08_14470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KS08_14475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS08_14480	COG2252	PERMEase
KS08_14485	COG4473	ABC transporter
KS08_14490	COG1131	(ABC) transporter
KS08_14495	COG1349	DNA-binding transcription factor activity
KS08_14500	COG1187	pseudouridine synthase activity
KS08_14505	COG2244	polysaccharide biosynthetic process
KS08_14510	COG2081	HI0933 family
KS08_14515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KS08_14545	COG1486	melibiose metabolic process
KS08_14555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KS08_14570	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_14570	COG2202	Pas domain
KS08_14575	COG2814	Major facilitator Superfamily
KS08_14580	COG5522	Integral membrane protein (intg_mem_TP0381)
KS08_14585	COG0577	efflux transmembrane transporter activity
KS08_14590	COG1136	(ABC) transporter
KS08_14595	COG2205	protein histidine kinase activity
KS08_14600	COG0745	RESPONSE REGULATOR receiver
KS08_14605	COG0577	efflux transmembrane transporter activity
KS08_14610	COG1136	(ABC) transporter
KS08_14630	COG1131	(ABC) transporter
KS08_14635	COG1725	Transcriptional regulator
KS08_14650	COG1242	4 iron, 4 sulfur cluster binding
KS08_14655	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KS08_14670	COG2267	carboxylic ester hydrolase activity
KS08_14675	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KS08_14680	COG1113	amino acid transport
KS08_14685	COG0367	asparagine synthase
KS08_14705	COG1506	peptidase
KS08_14710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KS08_14715	COG1116	anion transmembrane transporter activity
KS08_14720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KS08_14725	COG0494	nUDIX hydrolase
KS08_14730	COG4824	toxin secretion phage lysis holin
KS08_14735	COG0783	Belongs to the Dps family
KS08_14760	COG0288	reversible hydration of carbon dioxide
KS08_14770	COG1271	oxidase subunit
KS08_14775	COG1294	oxidase, subunit
KS08_14785	COG4948	Mandelate Racemase Muconate Lactonizing
KS08_14795	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KS08_14800	COG0596	Alpha beta hydrolase
KS08_14810	COG1169	isochorismate synthase
KS08_14815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KS08_14820	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KS08_14945	COG3859	Proton-coupled thiamine transporter YuaJ
KS08_14950	COG2268	Band 7 protein
KS08_14955	COG1585	Membrane protein implicated in regulation of membrane protease activity
KS08_14960	COG2318	DinB family
KS08_14970	COG1454	alcohol dehydrogenase
KS08_14980	COG1510	regulation of RNA biosynthetic process
KS08_14990	COG0569	domain protein
KS08_14995	COG1705	Flagellar rod assembly protein muramidase FlgJ
KS08_15000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KS08_15000	COG1017	nitric oxide dioxygenase activity
KS08_15020	COG0457	Tetratricopeptide repeat
KS08_15075	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_15080	COG4824	toxin secretion phage lysis holin
KS08_15100	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_15115	COG5412	phage tail tape measure protein
KS08_15115	COG3953	SLT domain
KS08_15250	COG0582	viral genome integration into host DNA
KS08_15265	COG0628	permease
KS08_15270	COG0673	inositol 2-dehydrogenase activity
KS08_15275	COG0693	protein deglycase activity
KS08_15280	COG0840	transmembrane signaling receptor activity
KS08_15285	COG0840	transmembrane signaling receptor activity
KS08_15290	COG0840	transmembrane signaling receptor activity
KS08_15295	COG0840	transmembrane signaling receptor activity
KS08_15310	COG2070	2-Nitropropane dioxygenase
KS08_15320	COG0366	Alpha amylase catalytic
KS08_15325	COG1253	flavin adenine dinucleotide binding
KS08_15330	COG2738	Putative neutral zinc metallopeptidase
KS08_15345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KS08_15365	COG1979	alcohol dehydrogenase
KS08_15370	COG1979	alcohol dehydrogenase
KS08_15375	COG2155	Conserved Protein
KS08_15380	COG1098	S1 RNA binding domain
KS08_15385	COG0436	Aminotransferase
KS08_15390	COG1522	sequence-specific DNA binding
KS08_15395	COG2267	carboxylic ester hydrolase activity
KS08_15405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KS08_15410	COG2205	protein histidine kinase activity
KS08_15420	COG5018	Exonuclease
KS08_15425	COG2814	Major facilitator Superfamily
KS08_15430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS08_15435	COG3011	Protein conserved in bacteria
KS08_15445	COG3290	protein histidine kinase activity
KS08_15450	COG4565	transcriptional regulatory protein
KS08_15480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KS08_15480	COG2111	Na H antiporter
KS08_15485	COG2111	Na H antiporter
KS08_15490	COG1006	Multisubunit Na H antiporter MnhC subunit
KS08_15495	COG0651	ATP synthesis coupled electron transport
KS08_15500	COG1863	multisubunit Na H antiporter MnhE subunit
KS08_15505	COG2212	antiporter activity
KS08_15510	COG1320	monovalent cation:proton antiporter activity
KS08_15515	COG2050	protein possibly involved in aromatic compounds catabolism
KS08_15520	COG2197	response regulator
KS08_15525	COG4585	Histidine kinase
KS08_15535	COG0142	geranyltranstransferase activity
KS08_15550	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KS08_15555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KS08_15560	COG1335	isochorismatase
KS08_15565	COG5506	Protein of unknown function (DUF1694)
KS08_15580	COG0628	permease
KS08_15590	COG1418	mRNA catabolic process
KS08_15595	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_15605	COG1511	domain protein
KS08_15610	COG1674	ftsk spoiiie
KS08_15610	COG0433	COG0433 Predicted ATPase
KS08_15615	COG4499	WXG100 protein secretion system (Wss), protein YukC
KS08_15620	COG5417	Belongs to the EsaB family
KS08_15625	COG4842	Belongs to the WXG100 family
KS08_15630	COG2508	Transcriptional regulator
KS08_15630	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KS08_15635	COG0686	Belongs to the AlaDH PNT family
KS08_15640	COG5634	Uncharacterized conserved protein (DUF2278)
KS08_15645	COG3251	PFAM MbtH domain protein
KS08_15650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_15655	COG1535	isochorismatase
KS08_15655	COG3433	isochorismatase activity
KS08_15660	COG1021	2,3-dihydroxybenzoate-AMP ligase
KS08_15665	COG1169	isochorismate synthase
KS08_15670	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_15675	COG2819	hydrolase of the alpha beta superfamily
KS08_15680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KS08_15685	COG1268	BioY protein
KS08_15690	COG2056	Na+-H+ antiporter family
KS08_15700	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KS08_15705	COG3584	3D domain protein
KS08_15715	COG1252	NADH dehydrogenase
KS08_15740	COG1131	(ABC) transporter
KS08_15770	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KS08_15790	COG3409	Peptidoglycan-binding domain 1 protein
KS08_15790	COG1388	LysM domain
KS08_15790	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_15815	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_15825	COG1705	Flagellar rod assembly protein muramidase FlgJ
KS08_15910	COG0582	viral genome integration into host DNA
KS08_16015	COG4974	Belongs to the 'phage' integrase family
KS08_16020	COG0316	Belongs to the HesB IscA family
KS08_16030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KS08_16040	COG1252	NADH dehydrogenase
KS08_16045	COG4837	Protein of unknown function (DUF1462)
KS08_16050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KS08_16055	COG1506	peptidase
KS08_16055	COG4946	Tricorn protease homolog
KS08_16055	COG0823	Involved in the tonB-independent uptake of proteins
KS08_16065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KS08_16070	COG0460	homoserine dehydrogenase
KS08_16075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KS08_16080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KS08_16085	COG0647	UMP catabolic process
KS08_16090	COG2445	Protein of unknown function DUF86
KS08_16095	COG4470	Protein conserved in bacteria
KS08_16105	COG0739	heme binding
KS08_16115	COG0737	Belongs to the 5'-nucleotidase family
KS08_16120	COG0730	response to heat
KS08_16125	COG1801	Protein of unknown function DUF72
KS08_16140	COG2508	Transcriptional regulator
KS08_16150	COG2814	Major facilitator Superfamily
KS08_16155	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KS08_16160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS08_16165	COG2356	endonuclease I
KS08_16170	COG3842	ATPase activity
KS08_16175	COG2188	Transcriptional regulator
KS08_16180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KS08_16185	COG0395	ABC-type sugar transport system, permease component
KS08_16190	COG1175	transmembrane transport
KS08_16195	COG1653	transport
KS08_16200	COG2222	sugar isomerase
KS08_16205	COG0789	Transcriptional regulator
KS08_16230	COG0322	excinuclease ABC activity
KS08_16235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS08_16250	COG3409	Peptidoglycan-binding domain 1 protein
KS08_16255	COG0719	Fe-S assembly protein
KS08_16260	COG0822	iron-sulfur transferase activity
KS08_16265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KS08_16270	COG0719	Fe-S assembly protein
KS08_16275	COG0396	ATPase activity
KS08_16285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KS08_16290	COG1464	Belongs to the NlpA lipoprotein family
KS08_16295	COG2011	ABC-type metal ion transport system permease component
KS08_16300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KS08_16310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_16315	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KS08_16330	COG1393	Belongs to the ArsC family
KS08_16335	COG1960	acyl-CoA dehydrogenase activity
KS08_16340	COG0183	Belongs to the thiolase family
KS08_16345	COG1250	3-hydroxyacyl-CoA dehydrogenase
KS08_16345	COG1024	Enoyl-CoA hydratase
KS08_16365	COG5577	PFAM Coat F domain
KS08_16370	COG1846	Transcriptional regulator
KS08_16375	COG0477	Major facilitator Superfamily
KS08_16400	COG1120	ATPase activity
KS08_16415	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_16420	COG0783	Belongs to the Dps family
KS08_16425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS08_16430	COG0745	RESPONSE REGULATOR receiver
KS08_16435	COG2770	Histidine kinase
KS08_16435	COG2205	protein histidine kinase activity
KS08_16445	COG1309	transcriptional regulator
KS08_16450	COG0114	fumarate hydratase activity
KS08_16460	COG0697	spore germination
KS08_16465	COG0814	amino acid
KS08_16475	COG2197	response regulator
KS08_16480	COG4585	Histidine kinase
KS08_16485	COG4758	membrane
KS08_16490	COG3595	metallopeptidase activity
KS08_16495	COG1842	Phage shock protein A
KS08_16500	COG4758	membrane
KS08_16505	COG2814	Major facilitator Superfamily
KS08_16510	COG2096	Adenosyltransferase
KS08_16515	COG1120	ATPase activity
KS08_16520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_16525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS08_16530	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_16535	COG3386	PFAM SMP-30 Gluconolaconase
KS08_16540	COG2205	protein histidine kinase activity
KS08_16545	COG0745	RESPONSE REGULATOR receiver
KS08_16555	COG1191	sigma factor activity
KS08_16565	COG2140	Oxalate decarboxylase
KS08_16575	COG1120	ATPase activity
KS08_16580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_16585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_16590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS08_16595	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KS08_16600	COG0531	amino acid
KS08_16610	COG1988	membrane-bound metal-dependent
KS08_16615	COG1368	sulfuric ester hydrolase activity
KS08_16620	COG1910	domain protein
KS08_16625	COG0725	ABC transporter, periplasmic molybdate-binding protein
KS08_16630	COG4149	molybdate abc transporter
KS08_16635	COG2197	response regulator
KS08_16645	COG1131	(ABC) transporter
KS08_16655	COG0842	Transport permease protein
KS08_16660	COG0656	L-ascorbic acid biosynthetic process
KS08_16680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KS08_16685	COG3973	AAA domain
KS08_16690	COG2860	membrane
KS08_16700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KS08_16705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KS08_16710	COG2217	Heavy metal translocating P-type atpase
KS08_16715	COG2217	Heavy metal translocating P-type atpase
KS08_16720	COG2608	mercury ion transmembrane transporter activity
KS08_16725	COG1937	Protein conserved in bacteria
KS08_16730	COG0673	inositol 2-dehydrogenase activity
KS08_16740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_16745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KS08_16750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_16755	COG1126	abc transporter atp-binding protein
KS08_16760	COG0765	amino acid transport
KS08_16765	COG0765	amino acid transport
KS08_16770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_16775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_16780	COG0454	-acetyltransferase
KS08_16785	COG0583	DNA-binding transcription factor activity
KS08_16790	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_16795	COG2732	(Barnase) inhibitor
KS08_16805	COG0557	exoribonuclease II activity
KS08_16810	COG1647	Serine aminopeptidase, S33
KS08_16815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KS08_16820	COG1476	TRANSCRIPTIONal
KS08_16825	COG1396	sequence-specific DNA binding
KS08_16830	COG1396	sequence-specific DNA binding
KS08_16835	COG1733	regulation of RNA biosynthetic process
KS08_16865	COG1174	glycine betaine transport
KS08_16870	COG1732	Glycine betaine
KS08_16875	COG1174	glycine betaine transport
KS08_16880	COG0517	IMP dehydrogenase activity
KS08_16880	COG1125	glycine betaine transport
KS08_16885	COG1510	regulation of RNA biosynthetic process
KS08_16890	COG1174	glycine betaine transport
KS08_16895	COG1732	Glycine betaine
KS08_16900	COG1174	glycine betaine transport
KS08_16905	COG0517	IMP dehydrogenase activity
KS08_16905	COG1125	glycine betaine transport
KS08_16910	COG1510	regulation of RNA biosynthetic process
KS08_16915	COG2095	MarC family integral membrane protein
KS08_16920	COG3064	Membrane
KS08_16930	COG0456	acetyltransferase
KS08_16945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KS08_16965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS08_16970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KS08_16980	COG2234	aminopeptidase activity
KS08_17000	COG0126	phosphoglycerate kinase activity
KS08_17010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KS08_17015	COG2390	Transcriptional regulator
KS08_17020	COG2814	Major facilitator Superfamily
KS08_17025	COG1609	Transcriptional regulator
KS08_17030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_17035	COG0583	DNA-binding transcription factor activity
KS08_17040	COG0697	spore germination
KS08_17045	COG1113	amino acid transport
KS08_17050	COG1737	Transcriptional regulator
KS08_17055	COG1070	Carbohydrate kinase
KS08_17080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_17085	COG2186	Transcriptional regulator
KS08_17090	COG1620	l-lactate permease
KS08_17095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KS08_17105	COG5039	Polysaccharide pyruvyl transferase
KS08_17110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KS08_17115	COG0110	maltose O-acetyltransferase activity
KS08_17120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KS08_17125	COG2244	polysaccharide biosynthetic process
KS08_17130	COG1216	Glycosyl transferase, family 2
KS08_17135	COG5039	Polysaccharide pyruvyl transferase
KS08_17140	COG1216	Glycosyl transferase, family 2
KS08_17150	COG0438	transferase activity, transferring glycosyl groups
KS08_17155	COG1215	transferase activity, transferring glycosyl groups
KS08_17160	COG0438	transferase activity, transferring glycosyl groups
KS08_17165	COG1086	Polysaccharide biosynthesis protein
KS08_17170	COG0489	protein tyrosine kinase activity
KS08_17175	COG3944	biosynthesis protein
KS08_17180	COG1396	sequence-specific DNA binding
KS08_17185	COG2272	Belongs to the type-B carboxylesterase lipase family
KS08_17195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KS08_17210	COG2364	Membrane
KS08_17215	COG0456	acetyltransferase
KS08_17220	COG3479	Phenolic acid decarboxylase
KS08_17265	COG2223	nitrite transmembrane transporter activity
KS08_17270	COG1609	Transcriptional regulator
KS08_17280	COG0583	DNA-binding transcription factor activity
KS08_17285	COG2828	Protein conserved in bacteria
KS08_17290	COG0477	Major facilitator Superfamily
KS08_17290	COG2814	Major facilitator Superfamily
KS08_17300	COG1611	Belongs to the LOG family
KS08_17305	COG1694	Mazg nucleotide pyrophosphohydrolase
KS08_17310	COG0659	secondary active sulfate transmembrane transporter activity
KS08_17315	COG0288	reversible hydration of carbon dioxide
KS08_17325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KS08_17330	COG4290	ribonuclease
KS08_17335	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KS08_17340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_17350	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KS08_17360	COG1051	belongs to the nudix hydrolase family
KS08_17365	COG0492	ferredoxin-NADP+ reductase activity
KS08_17370	COG0791	NLP P60 protein
KS08_17370	COG3883	PFAM NLP P60 protein
KS08_17375	COG0457	Tetratricopeptide repeat
KS08_17380	COG5002	protein histidine kinase activity
KS08_17385	COG0745	RESPONSE REGULATOR receiver
KS08_17390	COG1132	(ABC) transporter
KS08_17395	COG0140	phosphoribosyl-ATP diphosphatase activity
KS08_17395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KS08_17420	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KS08_17435	COG4990	cell redox homeostasis
KS08_17440	COG0110	maltose O-acetyltransferase activity
KS08_17460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KS08_17475	COG1309	transcriptional regulator
KS08_17480	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KS08_17485	COG1950	PFAM Membrane protein of
KS08_17490	COG1983	PspC domain protein
KS08_17495	COG3595	metallopeptidase activity
KS08_17510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KS08_17520	COG4897	Protein conserved in bacteria
KS08_17525	COG3848	Pyruvate phosphate dikinase
KS08_17525	COG0574	Belongs to the PEP-utilizing enzyme family
KS08_17530	COG1309	transcriptional regulator
KS08_17535	COG2814	Major facilitator Superfamily
KS08_17550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS08_17560	COG0793	Belongs to the peptidase S41A family
KS08_17560	COG3409	Peptidoglycan-binding domain 1 protein
KS08_17565	COG3420	alginic acid biosynthetic process
KS08_17570	COG2177	Part of the ABC transporter FtsEX involved in
KS08_17575	COG2884	Cell division ATP-binding protein ftsE
KS08_17580	COG2010	Cytochrome c
KS08_17585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_17590	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KS08_17600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KS08_17615	COG1516	flagellar protein fliS
KS08_17620	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KS08_17625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KS08_17645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KS08_17650	COG1256	bacterial-type flagellum assembly
KS08_17650	COG4786	Flagellar basal body rod
KS08_17655	COG3418	PFAM FlgN family protein
KS08_17660	COG2747	anti-sigma28 factor FlgM
KS08_17670	COG1040	competence protein
KS08_17680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KS08_17685	COG1307	EDD domain protein, DegV family
KS08_17690	COG2197	response regulator
KS08_17695	COG4585	Histidine kinase
KS08_17700	COG1739	Uncharacterized protein family UPF0029
KS08_17705	COG1316	TRANSCRIPTIONal
KS08_17710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KS08_17715	COG0438	transferase activity, transferring glycosyl groups
KS08_17720	COG1215	transferase activity, transferring glycosyl groups
KS08_17725	COG3206	protein involved in exopolysaccharide biosynthesis
KS08_17730	COG3307	-O-antigen
KS08_17735	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KS08_17740	COG0438	transferase activity, transferring glycosyl groups
KS08_17740	COG0297	glycogen (starch) synthase activity
KS08_17745	COG2244	polysaccharide biosynthetic process
KS08_17755	COG2247	cell wall binding repeat
KS08_17755	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS08_17760	COG2247	cell wall binding repeat
KS08_17760	COG2385	sporulation resulting in formation of a cellular spore
KS08_17770	COG1316	TRANSCRIPTIONal
KS08_17775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KS08_17780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KS08_17785	COG1134	teichoic acid transport
KS08_17790	COG1682	transport, permease protein
KS08_17795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KS08_17800	COG0438	transferase activity, transferring glycosyl groups
KS08_17805	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KS08_17810	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KS08_17815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KS08_17820	COG4193	domain, Protein
KS08_17825	COG1482	cell wall glycoprotein biosynthetic process
KS08_17830	COG0697	spore germination
KS08_17835	COG0814	amino acid
KS08_17845	COG1215	transferase activity, transferring glycosyl groups
KS08_17850	COG2814	Major facilitator Superfamily
KS08_17855	COG1316	TRANSCRIPTIONal
KS08_17860	COG0561	phosphatase activity
KS08_17865	COG2433	Pfam Transposase IS66
KS08_17870	COG0791	NLP P60 protein
KS08_17880	COG2843	Capsule synthesis protein
KS08_17890	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KS08_17895	COG0697	spore germination
KS08_17900	COG0814	amino acid
KS08_17910	COG1609	Transcriptional regulator
KS08_17915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KS08_17925	COG1129	ABC transporter
KS08_17930	COG1172	Belongs to the binding-protein-dependent transport system permease family
KS08_17935	COG1879	ABC-type sugar transport system periplasmic component
KS08_17940	COG3103	Sh3 type 3 domain protein
KS08_17945	COG2249	NAD(P)H dehydrogenase (quinone) activity
KS08_17950	COG3527	Alpha-acetolactate decarboxylase
KS08_17955	COG0028	Belongs to the TPP enzyme family
KS08_17960	COG0583	DNA-binding transcription factor activity
KS08_17965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KS08_17980	COG5337	Spore coat protein CotH
KS08_17990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KS08_18000	COG0405	Gamma-glutamyltransferase
KS08_18005	COG1522	sequence-specific DNA binding
KS08_18010	COG2059	Chromate
KS08_18015	COG2059	Chromate
KS08_18045	COG5444	nuclease activity
KS08_18060	COG3878	Protein conserved in bacteria
KS08_18065	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KS08_18070	COG4464	protein tyrosine phosphatase activity
KS08_18075	COG0489	protein tyrosine kinase activity
KS08_18080	COG3944	biosynthesis protein
KS08_18090	COG4715	Zinc finger, swim domain protein
KS08_18095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KS08_18100	COG0561	phosphatase activity
KS08_18105	COG1349	DNA-binding transcription factor activity
KS08_18110	COG0629	single-stranded DNA binding
KS08_18135	COG0457	Tetratricopeptide repeat
KS08_18140	COG4786	Flagellar basal body rod
KS08_18145	COG4786	Flagellar basal body rod
KS08_18150	COG1077	Cell shape determining protein MreB Mrl
KS08_18155	COG1609	Transcriptional regulator
KS08_18160	COG1846	Transcriptional regulator
KS08_18165	COG2814	Major facilitator Superfamily
KS08_18170	COG1953	Uracil, thiamine, allantoin
KS08_18180	COG1335	isochorismatase
KS08_18185	COG0004	ammonium transporteR
KS08_18190	COG0347	Belongs to the P(II) protein family
KS08_18195	COG0772	Belongs to the SEDS family
KS08_18200	COG0671	phosphoesterase, PA-phosphatase related
KS08_18210	COG0739	heme binding
KS08_18215	COG1247	-acetyltransferase
KS08_18230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KS08_18245	COG2910	NAD(P)H-binding
KS08_18250	COG1959	2 iron, 2 sulfur cluster binding
KS08_18265	COG0831	urea catabolic process
KS08_18270	COG3237	CsbD-like
KS08_18275	COG1994	Peptidase M50
KS08_18280	COG0457	Tetratricopeptide repeat
KS08_18290	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KS08_18300	COG2304	oxidoreductase activity
KS08_18305	COG2304	oxidoreductase activity
KS08_18310	COG2385	sporulation resulting in formation of a cellular spore
KS08_18315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KS08_18325	COG4836	Membrane
KS08_18365	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KS08_18395	COG0698	ribose 5-phosphate isomerase
KS08_18400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KS08_18410	COG0009	L-threonylcarbamoyladenylate synthase
KS08_18415	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KS08_18435	COG2890	protein-(glutamine-N5) methyltransferase activity
KS08_18440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KS08_18445	COG0346	lactoylglutathione lyase activity
KS08_18450	COG0789	Transcriptional regulator
KS08_18455	COG0679	Auxin Efflux Carrier
KS08_18460	COG0281	malic enzyme
KS08_18470	COG0254	rRNA binding
KS08_18475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KS08_18480	COG1494	fructose-1,6-bisphosphatase
KS08_18485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KS08_18495	COG0191	fructose-bisphosphate aldolase activity
KS08_18500	COG2204	response regulator
KS08_18505	COG4821	SIS domain
KS08_18520	COG2181	nitrate reductase activity
KS08_18520	COG0247	lactate metabolic process
KS08_18525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KS08_18540	COG1132	(ABC) transporter
KS08_18545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KS08_18550	COG2181	nitrate reductase activity
KS08_18555	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KS08_18560	COG1140	nitrate reductase beta subunit
KS08_18565	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KS08_18570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KS08_18580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KS08_18585	COG2223	nitrite transmembrane transporter activity
KS08_18595	COG4506	Protein conserved in bacteria
KS08_18605	COG3391	amine dehydrogenase activity
KS08_18615	COG0457	Tetratricopeptide repeat
KS08_18625	COG0010	Belongs to the arginase family
KS08_18630	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KS08_18635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS08_18650	COG1994	Peptidase M50
KS08_18655	COG1942	4-Oxalocrotonate Tautomerase
KS08_18660	COG1846	Transcriptional regulator
KS08_18665	COG0531	amino acid
KS08_18670	COG3465	dGTPase activity
KS08_18675	COG1078	dGTPase activity
KS08_18690	COG1695	Transcriptional regulator
KS08_18705	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KS08_18735	COG0583	DNA-binding transcription factor activity
KS08_18740	COG2855	membrane
KS08_18745	COG0280	phosphate acetyltransferase
KS08_18755	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_18760	COG0436	Aminotransferase
KS08_18770	COG0151	Belongs to the GarS family
KS08_18780	COG1917	Cupin 2, conserved barrel domain protein
KS08_18785	COG0077	Prephenate dehydratase
KS08_18790	COG2814	Major facilitator Superfamily
KS08_18795	COG2814	Major facilitator Superfamily
KS08_18800	COG0833	amino acid
KS08_18805	COG4187	Peptidase family M20/M25/M40
KS08_18810	COG1012	belongs to the aldehyde dehydrogenase family
KS08_18815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KS08_18825	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KS08_18830	COG1091	dTDP-4-dehydrorhamnose reductase activity
KS08_18835	COG1088	dTDP-glucose 4,6-dehydratase activity
KS08_18840	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KS08_18845	COG3980	spore coat polysaccharide biosynthesis protein
KS08_18850	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KS08_18855	COG2089	acid synthase
KS08_18860	COG0456	acetyltransferase
KS08_18865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KS08_18870	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KS08_18875	COG0463	Glycosyl transferase, family 2
KS08_18885	COG2363	Small membrane protein
KS08_18890	COG2233	PERMEase
KS08_18905	COG1216	Glycosyl transferase, family 2
KS08_18915	COG0351	phosphomethylpyrimidine kinase
KS08_18925	COG1621	beta-fructofuranosidase activity
KS08_18930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_18930	COG1263	PTS System
KS08_18935	COG3711	transcriptional antiterminator
KS08_18945	COG1404	Belongs to the peptidase S8 family
KS08_18950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_18955	COG2378	regulation of single-species biofilm formation
KS08_18975	COG0778	Nitroreductase
KS08_18980	COG0772	Belongs to the SEDS family
KS08_18985	COG0454	-acetyltransferase
KS08_19005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KS08_19010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KS08_19015	COG2261	transglycosylase associated protein
KS08_19020	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KS08_19025	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KS08_19030	COG2246	polysaccharide biosynthetic process
KS08_19035	COG1309	transcriptional regulator
KS08_19055	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KS08_19060	COG2837	iron assimilation
KS08_19065	COG2822	iron ion transport
KS08_19070	COG0672	)-iron permease
KS08_19085	COG0583	DNA-binding transcription factor activity
KS08_19095	COG1346	cytolysis
KS08_19100	COG4895	conserved protein (DUF2196)
KS08_19105	COG0789	Transcriptional regulator
KS08_19110	COG5504	Zn-dependent protease
KS08_19115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KS08_19120	COG0346	lactoylglutathione lyase activity
KS08_19125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KS08_19130	COG1404	Belongs to the peptidase S8 family
KS08_19135	COG1442	glycosyl transferase family 8
KS08_19140	COG2357	RelA SpoT domain protein
KS08_19145	COG1575	Belongs to the MenA family. Type 1 subfamily
KS08_19165	COG0697	spore germination
KS08_19170	COG0589	response to stress
KS08_19175	COG2723	6-phospho-beta-galactosidase activity
KS08_19180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_19180	COG1263	PTS System
KS08_19180	COG2190	(PTS) system
KS08_19195	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KS08_19220	COG3507	Belongs to the glycosyl hydrolase 43 family
KS08_19245	COG0010	Belongs to the arginase family
KS08_19250	COG0833	amino acid
KS08_19255	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KS08_19260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KS08_19275	COG0561	phosphatase activity
KS08_19305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS08_19310	COG5294	Protein conserved in bacteria
KS08_19315	COG0577	efflux transmembrane transporter activity
KS08_19320	COG1136	(ABC) transporter
KS08_19325	COG2205	protein histidine kinase activity
KS08_19330	COG0745	RESPONSE REGULATOR receiver
KS08_19345	COG1082	Xylose isomerase domain protein TIM barrel
KS08_19355	COG2814	Major facilitator Superfamily
KS08_19385	COG1349	DNA-binding transcription factor activity
KS08_19390	COG0667	Aldo Keto reductase
KS08_19395	COG2814	Major facilitator Superfamily
KS08_19405	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_19410	COG2197	response regulator
KS08_19415	COG4585	Histidine kinase
KS08_19420	COG3239	Fatty acid desaturase
KS08_19425	COG1309	transcriptional regulator
KS08_19430	COG1012	belongs to the aldehyde dehydrogenase family
KS08_19435	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KS08_19445	COG0640	Transcriptional regulator
KS08_19450	COG2814	Major facilitator Superfamily
KS08_19455	COG1714	RDD family
KS08_19465	COG0450	alkyl hydroperoxide reductase
KS08_19470	COG3634	alkyl hydroperoxide reductase activity
KS08_19480	COG1113	amino acid transport
KS08_19510	COG2080	2 iron, 2 sulfur cluster binding
KS08_19520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KS08_19525	COG2068	MobA-Related Protein
KS08_19530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KS08_19575	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KS08_19580	COG0667	Aldo Keto reductase
KS08_19585	COG0456	acetyltransferase
KS08_19590	COG0457	Tetratricopeptide repeat
KS08_19595	COG0010	Belongs to the arginase family
KS08_19600	COG0833	amino acid
KS08_19605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KS08_19610	COG5658	integral membrane protein
KS08_19615	COG0640	Transcriptional regulator
KS08_19620	COG3829	transcription factor binding
KS08_19635	COG5002	protein histidine kinase activity
KS08_19635	COG3850	Histidine kinase
KS08_19640	COG0745	RESPONSE REGULATOR receiver
KS08_19650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS08_19655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KS08_19660	COG4853	Protein conserved in bacteria
KS08_19665	COG4863	YycH protein
KS08_19670	COG5002	protein histidine kinase activity
KS08_19675	COG0745	RESPONSE REGULATOR receiver
KS08_19710	COG0346	lactoylglutathione lyase activity
KS08_19715	COG0305	Participates in initiation and elongation during chromosome replication
KS08_19735	COG3093	addiction module antidote protein HigA
KS08_19755	COG0438	transferase activity, transferring glycosyl groups
KS08_19775	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KS08_19780	COG4241	membrane
KS08_19790	COG5577	PFAM Coat F domain
KS08_19795	COG1733	regulation of RNA biosynthetic process
KS08_19805	COG0697	spore germination
KS08_19810	COG1621	beta-fructofuranosidase activity
KS08_19815	COG1621	beta-fructofuranosidase activity
KS08_19825	COG2318	DinB family
KS08_19830	COG2211	Major facilitator Superfamily
KS08_19840	COG0778	Nitroreductase
KS08_19845	COG1846	Transcriptional regulator
KS08_19850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_19855	COG1846	Transcriptional regulator
KS08_19860	COG2153	protein acetylation
KS08_19870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_19875	COG0697	spore germination
KS08_19880	COG1331	Highly conserved protein containing a thioredoxin domain
KS08_19890	COG1331	Highly conserved protein containing a thioredoxin domain
KS08_19895	COG1266	CAAX protease self-immunity
KS08_19900	COG2814	Major facilitator Superfamily
KS08_19900	COG0477	Major facilitator Superfamily
KS08_19905	COG0346	lactoylglutathione lyase activity
KS08_19910	COG1609	Transcriptional regulator
KS08_19915	COG0708	Exodeoxyribonuclease III
KS08_19920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KS08_19925	COG2169	Transcriptional regulator
KS08_19935	COG0629	single-stranded DNA binding
KS08_19945	COG0012	GTP binding
KS08_19950	COG0243	molybdopterin cofactor binding
KS08_19955	COG4481	Protein conserved in bacteria
KS08_19960	COG3949	Membrane
KS08_19975	COG1475	DNA binding
KS08_19980	COG1192	Involved in chromosome partitioning
KS08_20005	COG1847	R3H domain protein
KS08_20010	COG0706	membrane insertase activity
KS08_20020	COG0230	Belongs to the bacterial ribosomal protein bL34 family