locus-tag	class	description
BS21228_00060	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_00060	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_00060	COG1388	LysM domain
BS21228_00070	COG5444	nuclease activity
BS21228_00110	COG4282	regulation of fungal-type cell wall biogenesis
BS21228_00145	COG3655	Transcriptional regulator
BS21228_00170	COG0135	phosphoribosylanthranilate isomerase activity
BS21228_00175	COG2211	Major facilitator Superfamily
BS21228_00190	COG3507	Belongs to the glycosyl hydrolase 43 family
BS21228_00195	COG1940	carbohydrate kinase activity
BS21228_00200	COG2115	Belongs to the xylose isomerase family
BS21228_00205	COG1070	Carbohydrate kinase
BS21228_00215	COG3328	transposase activity
BS21228_00220	COG1525	nuclease
BS21228_00225	COG2814	Major facilitator Superfamily
BS21228_00230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BS21228_00245	COG0756	dUTP diphosphatase activity
BS21228_00285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS21228_00300	COG3832	glyoxalase III activity
BS21228_00345	COG4195	phage-related replication protein
BS21228_00355	COG0346	lactoylglutathione lyase activity
BS21228_00365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BS21228_00370	COG1388	LysM domain
BS21228_00375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BS21228_00380	COG4224	UPF0291 protein
BS21228_00385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BS21228_00395	COG3763	UPF0154 protein
BS21228_00405	COG0785	Cytochrome C biogenesis protein
BS21228_00410	COG2201	protein-glutamate methylesterase activity
BS21228_00415	COG4846	Membrane protein involved in cytochrome C biogenesis
BS21228_00425	COG0071	Belongs to the small heat shock protein (HSP20) family
BS21228_00440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BS21228_00445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_00465	COG0824	Thioesterase
BS21228_00475	COG4841	protein insertion into membrane
BS21228_00480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BS21228_00485	COG1832	CoA-binding protein
BS21228_00490	COG0187	DNA topoisomerase II activity
BS21228_00495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS21228_00505	COG1115	amino acid carrier protein
BS21228_00510	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BS21228_00520	COG5520	Belongs to the glycosyl hydrolase 30 family
BS21228_00530	COG2246	polysaccharide biosynthetic process
BS21228_00535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS21228_00540	COG0586	Pfam SNARE associated Golgi protein
BS21228_00545	COG2404	hydrolase activity, acting on ester bonds
BS21228_00550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BS21228_00555	COG1024	Enoyl-CoA hydratase
BS21228_00560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS21228_00565	COG0511	ligase activity, forming carbon-carbon bonds
BS21228_00570	COG0439	Biotin carboxylase
BS21228_00575	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_00580	COG1960	acyl-CoA dehydrogenase activity
BS21228_00590	COG1649	PFAM Uncharacterised BCR, COG1649
BS21228_00605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_00610	COG2027	D-alanyl-D-alanine carboxypeptidase
BS21228_00615	COG2017	converts alpha-aldose to the beta-anomer
BS21228_00620	COG0534	Mate efflux family protein
BS21228_00640	COG0582	viral genome integration into host DNA
BS21228_00645	COG0166	Belongs to the GPI family
BS21228_00650	COG0405	Gamma-glutamyltransferase
BS21228_00655	COG0583	DNA-binding transcription factor activity
BS21228_00660	COG0604	alcohol dehydrogenase
BS21228_00665	COG0493	'glutamate synthase
BS21228_00670	COG0067	glutamate synthase
BS21228_00670	COG0069	glutamate synthase activity
BS21228_00670	COG0070	glutamate synthase
BS21228_00675	COG0583	DNA-binding transcription factor activity
BS21228_00705	COG0300	oxidoreductase activity
BS21228_00710	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BS21228_00720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_00735	COG1131	(ABC) transporter
BS21228_00745	COG2814	Major facilitator Superfamily
BS21228_00750	COG3328	transposase activity
BS21228_00790	COG3328	transposase activity
BS21228_00845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS21228_00850	COG2226	methyltransferase
BS21228_00855	COG2211	Major facilitator Superfamily
BS21228_00860	COG3328	transposase activity
BS21228_00885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_00905	COG5444	nuclease activity
BS21228_00910	COG4282	regulation of fungal-type cell wall biogenesis
BS21228_00915	COG1231	oxidoreductase activity
BS21228_00920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS21228_00925	COG2207	Transcriptional regulator
BS21228_00925	COG0662	Cupin 2, conserved barrel domain protein
BS21228_00930	COG0456	acetyltransferase
BS21228_00935	COG1309	transcriptional regulator
BS21228_00940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_00945	COG3708	Transcriptional regulator
BS21228_00950	COG2378	regulation of single-species biofilm formation
BS21228_00960	COG0640	Transcriptional regulator
BS21228_00965	COG0741	lytic transglycosylase activity
BS21228_00970	COG2322	membrane
BS21228_00985	COG1619	proteins homologs of microcin C7 resistance protein MccF
BS21228_00990	COG3239	Fatty acid desaturase
BS21228_00995	COG4585	Histidine kinase
BS21228_01000	COG2197	response regulator
BS21228_01005	COG1388	LysM domain
BS21228_01005	COG3584	3D domain protein
BS21228_01010	COG0514	ATP-dependent DNA helicase (RecQ)
BS21228_01025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BS21228_01030	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS21228_01045	COG0071	Belongs to the small heat shock protein (HSP20) family
BS21228_01070	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_01075	COG1657	PFAM Prenyltransferase squalene oxidase
BS21228_01080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS21228_01085	COG0733	neurotransmitter:sodium symporter activity
BS21228_01090	COG0385	Bile acid
BS21228_01095	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS21228_01100	COG0567	Dehydrogenase, E1 component
BS21228_01105	COG4548	von Willebrand factor, type A
BS21228_01110	COG0714	Associated with various cellular activities
BS21228_01115	COG2032	superoxide dismutase activity
BS21228_01120	COG0791	NLP P60 protein
BS21228_01120	COG1388	LysM domain
BS21228_01125	COG1819	glycosyl
BS21228_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BS21228_01135	COG0534	Mate efflux family protein
BS21228_01140	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_01145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS21228_01150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS21228_01160	COG2962	Rard protein
BS21228_01180	COG1942	4-Oxalocrotonate Tautomerase
BS21228_01185	COG1733	regulation of RNA biosynthetic process
BS21228_01190	COG0778	Nitroreductase
BS21228_01200	COG0400	carboxylic ester hydrolase activity
BS21228_01215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS21228_01220	COG0793	Belongs to the peptidase S41A family
BS21228_01220	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_01225	COG2226	methyltransferase
BS21228_01235	COG1876	peptidase activity
BS21228_01240	COG0813	purine-nucleoside phosphorylase activity
BS21228_01255	COG0671	phosphoesterase, PA-phosphatase related
BS21228_01280	COG4479	Belongs to the UPF0346 family
BS21228_01290	COG1509	lysine 2,3-aminomutase activity
BS21228_01295	COG0456	acetyltransferase
BS21228_01300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS21228_01305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS21228_01310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS21228_01315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS21228_01325	COG0456	acetyltransferase
BS21228_01330	COG0463	Glycosyl transferase, family 2
BS21228_01345	COG4641	Protein conserved in bacteria
BS21228_01350	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BS21228_01355	COG1086	Polysaccharide biosynthesis protein
BS21228_01360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS21228_01365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS21228_01370	COG1846	Transcriptional regulator
BS21228_01375	COG0534	Mate efflux family protein
BS21228_01385	COG4698	Protein conserved in bacteria
BS21228_01390	COG2755	lipolytic protein G-D-S-L family
BS21228_01395	COG1999	signal sequence binding
BS21228_01405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BS21228_01410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BS21228_01415	COG1272	protein, Hemolysin III
BS21228_01420	COG0204	Acyl-transferase
BS21228_01425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS21228_01430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS21228_01440	COG2136	Putative SAM-dependent methyltransferase
BS21228_01440	COG2521	methyltransferase
BS21228_01450	COG0129	dihydroxy-acid dehydratase activity
BS21228_01455	COG1413	lyase activity
BS21228_01460	COG1418	mRNA catabolic process
BS21228_01465	COG0386	Belongs to the glutathione peroxidase family
BS21228_01470	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BS21228_01475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS21228_01480	COG1278	Cold shock
BS21228_01500	COG0328	RNA-DNA hybrid ribonuclease activity
BS21228_01505	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BS21228_01510	COG0328	RNA-DNA hybrid ribonuclease activity
BS21228_01520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS21228_01535	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS21228_01545	COG1755	Isoprenylcysteine carboxyl methyltransferase
BS21228_01550	COG3424	synthase
BS21228_01555	COG2233	PERMEase
BS21228_01560	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS21228_01565	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BS21228_01575	COG0800	Aldolase
BS21228_01580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS21228_01585	COG1609	Transcriptional regulator
BS21228_01590	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BS21228_01595	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_01600	COG1199	ATP-dependent helicase activity
BS21228_01615	COG0116	Belongs to the methyltransferase superfamily
BS21228_01630	COG4474	Belongs to the UPF0398 family
BS21228_01640	COG3359	exonuclease
BS21228_01645	COG1205	dead DEAH box helicase
BS21228_01645	COG1111	helicase
BS21228_01650	COG2190	(PTS) system
BS21228_01655	COG0071	Belongs to the small heat shock protein (HSP20) family
BS21228_01690	COG3331	DNA recombination
BS21228_01695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS21228_01695	COG4499	WXG100 protein secretion system (Wss), protein YukC
BS21228_01705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BS21228_01710	COG3935	DnaD domain protein
BS21228_01715	COG0017	Asparaginyl-tRNA synthetase
BS21228_01720	COG0436	Aminotransferase
BS21228_01725	COG5353	protein conserved in bacteria
BS21228_01735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BS21228_01735	COG1199	ATP-dependent helicase activity
BS21228_01740	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BS21228_01745	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BS21228_01750	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BS21228_01755	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BS21228_01755	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BS21228_01760	COG0617	tRNA 3'-terminal CCA addition
BS21228_01765	COG0438	transferase activity, transferring glycosyl groups
BS21228_01770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS21228_01775	COG1803	Methylglyoxal synthase
BS21228_01780	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BS21228_01785	COG1694	Mazg nucleotide pyrophosphohydrolase
BS21228_01790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_01800	COG4347	Protein of unknown function (DUF1405)
BS21228_01805	COG2010	Cytochrome c
BS21228_01805	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BS21228_01810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BS21228_01815	COG0723	plastoquinol--plastocyanin reductase activity
BS21228_01825	COG5582	Belongs to the UPF0302 family
BS21228_01830	COG0457	Tetratricopeptide repeat
BS21228_01835	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BS21228_01840	COG0287	Prephenate dehydrogenase
BS21228_01855	COG0133	tryptophan synthase activity
BS21228_01860	COG0135	phosphoribosylanthranilate isomerase activity
BS21228_01870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BS21228_01875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BS21228_01880	COG4401	Chorismate mutase type I
BS21228_01885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BS21228_01890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BS21228_01895	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BS21228_01900	COG0105	UTP biosynthetic process
BS21228_01905	COG0142	geranyltranstransferase activity
BS21228_01910	COG2226	methyltransferase
BS21228_01915	COG0142	geranyltranstransferase activity
BS21228_01925	COG0302	gtp cyclohydrolase
BS21228_01930	COG0776	regulation of translation
BS21228_01935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS21228_01950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BS21228_01955	COG1160	GTP binding
BS21228_01980	COG1304	FMN binding
BS21228_01985	COG0539	negative regulation of cytoplasmic translation
BS21228_01990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BS21228_02000	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BS21228_02005	COG2959	enzyme of heme biosynthesis
BS21228_02010	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_02010	COG3773	Cell wall hydrolase
BS21228_02015	COG2339	peptidase activity
BS21228_02020	COG0492	ferredoxin-NADP+ reductase activity
BS21228_02025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS21228_02030	COG4862	establishment of competence for transformation
BS21228_02035	COG1408	metallophosphoesterase
BS21228_02045	COG1388	LysM domain
BS21228_02050	COG1266	CAAX protease self-immunity
BS21228_02055	COG0514	ATP-dependent DNA helicase (RecQ)
BS21228_02060	COG4955	Helix-turn-helix domain
BS21228_02065	COG1141	Ferredoxin
BS21228_02070	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BS21228_02075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BS21228_02080	COG0710	3-dehydroquinate dehydratase activity
BS21228_02090	COG1595	DNA-templated transcription, initiation
BS21228_02095	COG5002	protein histidine kinase activity
BS21228_02100	COG0745	RESPONSE REGULATOR receiver
BS21228_02105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS21228_02110	COG1333	cytochrome c biogenesis protein
BS21228_02115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_02120	COG1187	pseudouridine synthase activity
BS21228_02125	COG0700	Nucleoside recognition
BS21228_02130	COG2715	membrane protein required for spore maturation
BS21228_02135	COG1686	Belongs to the peptidase S11 family
BS21228_02145	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BS21228_02150	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BS21228_02155	COG1547	Domain of unknown function (DUF309)
BS21228_02160	COG0456	acetyltransferase
BS21228_02165	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BS21228_02170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS21228_02170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS21228_02175	COG0307	riboflavin synthase, alpha
BS21228_02180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS21228_02180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS21228_02190	COG0681	Belongs to the peptidase S26 family
BS21228_02200	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BS21228_02210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS21228_02250	COG3328	transposase activity
BS21228_02300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS21228_02315	COG4086	secreted protein
BS21228_02320	COG0019	diaminopimelate decarboxylase activity
BS21228_02325	COG0697	spore germination
BS21228_02340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS21228_02360	COG1191	sigma factor activity
BS21228_02365	COG2172	sigma factor antagonist activity
BS21228_02370	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_02375	COG1686	Belongs to the peptidase S11 family
BS21228_02380	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BS21228_02385	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BS21228_02390	COG4974	Belongs to the 'phage' integrase family
BS21228_02400	COG0735	belongs to the Fur family
BS21228_02405	COG1300	Membrane
BS21228_02415	COG0281	malic enzyme
BS21228_02420	COG1757	Na H antiporter
BS21228_02425	COG1027	Aspartate ammonia-lyase
BS21228_02430	COG0252	asparaginase activity
BS21228_02435	COG1396	sequence-specific DNA binding
BS21228_02440	COG1379	DNA repair
BS21228_02445	COG0494	nUDIX hydrolase
BS21228_02455	COG0667	Aldo Keto reductase
BS21228_02465	COG1073	alpha beta
BS21228_02475	COG4918	Iron-sulphur cluster biosynthesis
BS21228_02480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BS21228_02480	COG0456	acetyltransferase
BS21228_02485	COG2329	Antibiotic biosynthesis monooxygenase
BS21228_02490	COG0456	acetyltransferase
BS21228_02500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS21228_02510	COG2211	Major facilitator Superfamily
BS21228_02520	COG0346	lactoylglutathione lyase activity
BS21228_02525	COG1072	(Pantothenic acid kinase))
BS21228_02530	COG3048	D-serine ammonia-lyase activity
BS21228_02535	COG0300	oxidoreductase activity
BS21228_02540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_02545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS21228_02550	COG4187	Peptidase family M20/M25/M40
BS21228_02555	COG1902	pentaerythritol trinitrate reductase activity
BS21228_02570	COG0596	Alpha beta hydrolase
BS21228_02580	COG1234	tRNA 3'-trailer cleavage
BS21228_02585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BS21228_02590	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BS21228_02595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS21228_02605	COG0706	membrane insertase activity
BS21228_02610	COG3361	conserved protein (COG2071)
BS21228_02615	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS21228_02625	COG0346	lactoylglutathione lyase activity
BS21228_02630	COG1376	ErfK ybiS ycfS ynhG family protein
BS21228_02635	COG4129	membrane
BS21228_02640	COG1126	abc transporter atp-binding protein
BS21228_02645	COG0765	amino acid transport
BS21228_02650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS21228_02660	COG1597	lipid kinase activity
BS21228_02670	COG0789	Transcriptional regulator
BS21228_02670	COG4978	Transcriptional regulator
BS21228_02675	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS21228_02680	COG0022	dehydrogenase e1 component
BS21228_02690	COG3426	butyrate kinase activity
BS21228_02695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS21228_02700	COG0280	phosphate acetyltransferase
BS21228_02705	COG3829	transcription factor binding
BS21228_02705	COG3290	protein histidine kinase activity
BS21228_02715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BS21228_02720	COG2079	MmgE PrpD family protein
BS21228_02725	COG0372	Belongs to the citrate synthase family
BS21228_02730	COG1960	acyl-CoA dehydrogenase activity
BS21228_02735	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS21228_02740	COG0183	Belongs to the thiolase family
BS21228_02745	COG0584	glycerophosphoryl diester phosphodiesterase
BS21228_02750	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_02760	COG1902	pentaerythritol trinitrate reductase activity
BS21228_02765	COG0745	RESPONSE REGULATOR receiver
BS21228_02775	COG0750	zinc metalloprotease
BS21228_02780	COG0497	DNA recombination
BS21228_02785	COG1438	arginine binding
BS21228_02790	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BS21228_02795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BS21228_02800	COG0142	geranyltranstransferase activity
BS21228_02805	COG1722	exodeoxyribonuclease VII activity
BS21228_02810	COG1570	exodeoxyribonuclease VII activity
BS21228_02815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BS21228_02820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BS21228_02825	COG1302	Protein conserved in bacteria
BS21228_02830	COG0439	Biotin carboxylase
BS21228_02835	COG0511	ligase activity, forming carbon-carbon bonds
BS21228_02880	COG3854	ATPases associated with a variety of cellular activities
BS21228_02890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BS21228_02895	COG0006	proline dipeptidase activity
BS21228_02900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BS21228_02910	COG3872	metal-dependent enzyme
BS21228_02920	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS21228_02925	COG1321	iron dependent repressor
BS21228_02930	COG0095	Lipoate-protein ligase
BS21228_02935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS21228_02940	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BS21228_02945	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BS21228_02950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BS21228_02955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS21228_02970	COG1396	sequence-specific DNA binding
BS21228_02980	COG0681	Belongs to the peptidase S26 family
BS21228_03005	COG4940	Competence protein ComGF
BS21228_03015	COG4970	Tfp pilus assembly protein FimT
BS21228_03020	COG4537	Required for transformation and DNA binding
BS21228_03025	COG1459	type II secretion system
BS21228_03030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BS21228_03035	COG0517	IMP dehydrogenase activity
BS21228_03040	COG0598	Magnesium transport protein CorA
BS21228_03045	COG1253	flavin adenine dinucleotide binding
BS21228_03050	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_03060	COG1393	Belongs to the ArsC family
BS21228_03070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_03080	COG0011	TIGRFAM Protein of
BS21228_03090	COG2866	Carboxypeptidase
BS21228_03095	COG1368	sulfuric ester hydrolase activity
BS21228_03100	COG1940	carbohydrate kinase activity
BS21228_03105	COG4483	Protein conserved in bacteria
BS21228_03110	COG0705	Rhomboid family
BS21228_03110	COG0457	Tetratricopeptide repeat
BS21228_03120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BS21228_03125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BS21228_03130	COG0438	transferase activity, transferring glycosyl groups
BS21228_03145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BS21228_03150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS21228_03155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS21228_03160	COG0581	inorganic phosphate transmembrane transporter activity
BS21228_03165	COG0573	inorganic phosphate transmembrane transporter activity
BS21228_03170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BS21228_03180	COG0477	Major facilitator Superfamily
BS21228_03185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS21228_03190	COG2839	Protein conserved in bacteria
BS21228_03195	COG5521	maltodextrose utilization protein MalA
BS21228_03200	COG1388	LysM domain
BS21228_03205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BS21228_03210	COG4709	membrane
BS21228_03215	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BS21228_03220	COG0735	belongs to the Fur family
BS21228_03225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_03235	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BS21228_03240	COG0513	Belongs to the DEAD box helicase family
BS21228_03250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BS21228_03255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BS21228_03260	COG2384	SAM-dependent methyltransferase
BS21228_03265	COG2010	Cytochrome c
BS21228_03275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BS21228_03280	COG0358	DNA primase activity
BS21228_03285	COG1671	Belongs to the UPF0178 family
BS21228_03290	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BS21228_03295	COG0517	IMP dehydrogenase activity
BS21228_03300	COG0751	glycine-tRNA ligase activity
BS21228_03305	COG0752	glycyl-tRNA synthetase alpha subunit
BS21228_03310	COG1381	Involved in DNA repair and RecF pathway recombination
BS21228_03320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BS21228_03325	COG0295	cytidine deaminase activity
BS21228_03330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BS21228_03335	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BS21228_03340	COG1480	7TM receptor with intracellular HD hydrolase
BS21228_03345	COG1702	phosphate starvation-inducible protein PhoH
BS21228_03350	COG0561	phosphatase activity
BS21228_03365	COG4864	UPF0365 protein
BS21228_03370	COG1030	water channel activity
BS21228_03375	COG1610	YqeY-like protein
BS21228_03380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BS21228_03390	COG1283	sodium-dependent phosphate transmembrane transporter activity
BS21228_03395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS21228_03400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BS21228_03405	COG2264	protein methyltransferase activity
BS21228_03410	COG0484	heat shock protein binding
BS21228_03415	COG0443	Heat shock 70 kDa protein
BS21228_03420	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BS21228_03425	COG1420	regulation of RNA biosynthetic process
BS21228_03430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS21228_03435	COG0481	GTPase activity
BS21228_03445	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_03450	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BS21228_03455	COG0268	Binds directly to 16S ribosomal RNA
BS21228_03460	COG1466	dna polymerase III delta subunit
BS21228_03470	COG0658	competence protein
BS21228_03470	COG2333	competence protein COMEC
BS21228_03475	COG2131	deaminase
BS21228_03480	COG1596	polysaccharide export
BS21228_03480	COG1555	photosystem II stabilization
BS21228_03485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS21228_03490	COG2226	methyltransferase
BS21228_03495	COG0799	negative regulation of ribosome biogenesis
BS21228_03500	COG1713	HD superfamily hydrolase involved in NAD metabolism
BS21228_03505	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BS21228_03510	COG1534	Rna-binding protein
BS21228_03515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BS21228_03520	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BS21228_03525	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BS21228_03535	COG2755	lipolytic protein G-D-S-L family
BS21228_03540	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_03540	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_03545	COG0398	Pfam SNARE associated Golgi protein
BS21228_03550	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BS21228_03560	COG3209	COG3209 Rhs family protein
BS21228_03570	COG3328	transposase activity
BS21228_03580	COG0114	fumarate hydratase activity
BS21228_03585	COG0583	DNA-binding transcription factor activity
BS21228_03600	COG0457	Tetratricopeptide repeat
BS21228_03720	COG4978	Transcriptional regulator
BS21228_03720	COG0789	Transcriptional regulator
BS21228_03725	COG2814	Major facilitator Superfamily
BS21228_03730	COG0456	acetyltransferase
BS21228_03735	COG1253	flavin adenine dinucleotide binding
BS21228_03745	COG0697	spore germination
BS21228_03750	COG0583	DNA-binding transcription factor activity
BS21228_03755	COG2072	flavoprotein involved in K transport
BS21228_03760	COG1230	cation diffusion facilitator family transporter
BS21228_03770	COG1114	Component of the transport system for branched-chain amino acids
BS21228_03775	COG1687	branched-chain amino acid
BS21228_03785	COG1522	sequence-specific DNA binding
BS21228_03790	COG2732	(Barnase) inhibitor
BS21228_03795	COG2124	cytochrome p450
BS21228_03805	COG1335	isochorismatase
BS21228_03815	COG2318	DinB family
BS21228_03825	COG2070	2-Nitropropane dioxygenase
BS21228_03840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS21228_03850	COG3443	Belongs to the bacterial solute-binding protein 9 family
BS21228_03855	COG1595	DNA-templated transcription, initiation
BS21228_03860	COG0667	Aldo Keto reductase
BS21228_03865	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_03870	COG5566	PFAM Mor transcription activator
BS21228_03875	COG0596	Alpha beta hydrolase
BS21228_03880	COG4991	sh3 domain protein
BS21228_03885	COG4991	sh3 domain protein
BS21228_03890	COG0346	lactoylglutathione lyase activity
BS21228_03900	COG5577	PFAM Coat F domain
BS21228_03905	COG1063	alcohol dehydrogenase
BS21228_03915	COG5577	PFAM Coat F domain
BS21228_03920	COG0789	Transcriptional regulator
BS21228_03930	COG1064	alcohol dehydrogenase
BS21228_03935	COG0693	protein deglycase activity
BS21228_03940	COG1621	beta-fructofuranosidase activity
BS21228_03945	COG3716	PTS system mannose fructose sorbose family IID component
BS21228_03950	COG3715	PTS system
BS21228_03955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_03960	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_03965	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BS21228_03965	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BS21228_03970	COG1113	amino acid transport
BS21228_03975	COG1280	lysine exporter protein (LysE YggA)
BS21228_03980	COG1378	Sugar-specific transcriptional regulator TrmB
BS21228_03985	COG1595	DNA-templated transcription, initiation
BS21228_04010	COG1309	transcriptional regulator
BS21228_04015	COG2226	methyltransferase
BS21228_04025	COG2116	formate transmembrane transporter activity
BS21228_04030	COG5609	conserved protein (DUF2294)
BS21228_04035	COG3383	formate dehydrogenase (NAD+) activity
BS21228_04040	COG2427	Protein of unknown function (DUF1641)
BS21228_04055	COG0626	cystathionine gamma-synthase activity
BS21228_04060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS21228_04065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BS21228_04070	COG2226	methyltransferase
BS21228_04085	COG0768	penicillin binding
BS21228_04090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS21228_04095	COG0572	uridine kinase
BS21228_04115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BS21228_04120	COG3906	Belongs to the UPF0473 family
BS21228_04125	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BS21228_04130	COG4472	Bacterial protein of unknown function (DUF965)
BS21228_04135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BS21228_04140	COG0628	permease
BS21228_04145	COG1126	abc transporter atp-binding protein
BS21228_04150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS21228_04155	COG0765	amino acid transport
BS21228_04160	COG0765	amino acid transport
BS21228_04175	COG3881	PFAM PRC-barrel domain
BS21228_04180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BS21228_04185	COG0457	Tetratricopeptide repeat
BS21228_04190	COG0482	sulfurtransferase activity
BS21228_04195	COG1104	cysteine desulfurase activity
BS21228_04200	COG1959	2 iron, 2 sulfur cluster binding
BS21228_04205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BS21228_04210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BS21228_04220	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BS21228_04225	COG0124	histidyl-tRNA synthetase
BS21228_04235	COG3103	Sh3 type 3 domain protein
BS21228_04235	COG4991	sh3 domain protein
BS21228_04235	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_04240	COG1490	D-aminoacyl-tRNA deacylase activity
BS21228_04245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BS21228_04250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS21228_04255	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BS21228_04255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BS21228_04260	COG5416	Lipopolysaccharide assembly protein A domain
BS21228_04265	COG0490	domain, Protein
BS21228_04270	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS21228_04270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS21228_04280	COG2244	polysaccharide biosynthetic process
BS21228_04285	COG2323	membrane
BS21228_04295	COG1862	Preprotein translocase
BS21228_04300	COG0343	queuine tRNA-ribosyltransferase activity
BS21228_04305	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BS21228_04315	COG2255	four-way junction helicase activity
BS21228_04320	COG0632	four-way junction helicase activity
BS21228_04330	COG2814	Major facilitator Superfamily
BS21228_04335	COG0673	inositol 2-dehydrogenase activity
BS21228_04340	COG2112	serine threonine protein kinase
BS21228_04355	COG1115	amino acid carrier protein
BS21228_04360	COG0217	transcriptional regulatory protein
BS21228_04370	COG1388	LysM domain
BS21228_04375	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BS21228_04380	COG0157	Belongs to the NadC ModD family
BS21228_04385	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BS21228_04390	COG1104	cysteine desulfurase activity
BS21228_04395	COG1827	regulation of RNA biosynthetic process
BS21228_04400	COG0077	Prephenate dehydratase
BS21228_04405	COG4492	Belongs to the UPF0735 family
BS21228_04410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BS21228_04415	COG3290	protein histidine kinase activity
BS21228_04420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BS21228_04425	COG2868	ribosomal protein
BS21228_04430	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BS21228_04435	COG1994	Peptidase M50
BS21228_04440	COG0739	heme binding
BS21228_04445	COG2894	cell division
BS21228_04450	COG0850	regulation of cytokinetic process
BS21228_04455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BS21228_04460	COG1792	Involved in formation and maintenance of cell shape
BS21228_04465	COG1077	Cell shape determining protein MreB Mrl
BS21228_04470	COG2003	Belongs to the UPF0758 family
BS21228_04475	COG0424	maF-like protein
BS21228_04485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BS21228_04490	COG0285	dihydrofolate synthase activity
BS21228_04495	COG0525	valine-tRNA ligase activity
BS21228_04505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS21228_04510	COG1388	LysM domain
BS21228_04515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS21228_04520	COG0113	porphobilinogen synthase activity
BS21228_04525	COG1587	Uroporphyrinogen-III synthase
BS21228_04530	COG0181	hydroxymethylbilane synthase activity
BS21228_04535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS21228_04540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BS21228_04550	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BS21228_04555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BS21228_04560	COG0470	DNA polymerase III
BS21228_04560	COG1067	ATP-dependent peptidase activity
BS21228_04565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BS21228_04570	COG0544	peptidyl-prolyl cis-trans isomerase activity
BS21228_04575	COG0457	Tetratricopeptide repeat
BS21228_04575	COG1477	protein flavinylation
BS21228_04580	COG0066	3-isopropylmalate dehydratase activity
BS21228_04585	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BS21228_04590	COG0473	3-isopropylmalate dehydrogenase activity
BS21228_04595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS21228_04600	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BS21228_04605	COG0440	acetolactate synthase activity
BS21228_04610	COG0028	Belongs to the TPP enzyme family
BS21228_04620	COG0454	-acetyltransferase
BS21228_04625	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BS21228_04655	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BS21228_04680	COG0622	Phosphoesterase
BS21228_04685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BS21228_04690	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BS21228_04695	COG5401	PFAM Sporulation and spore germination
BS21228_04700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS21228_04705	COG1846	Transcriptional regulator
BS21228_04710	COG2197	response regulator
BS21228_04715	COG0824	Thioesterase
BS21228_04720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BS21228_04725	COG1053	succinate dehydrogenase
BS21228_04730	COG2009	succinate dehydrogenase
BS21228_04735	COG1719	4-vinyl reductase, 4VR
BS21228_04740	COG0527	aspartate kinase activity
BS21228_04750	COG0322	excinuclease ABC activity
BS21228_04755	COG3118	belongs to the thioredoxin family
BS21228_04760	COG3534	alpha-L-arabinofuranosidase
BS21228_04765	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BS21228_04770	COG2086	electron transfer activity
BS21228_04775	COG1024	Enoyl-CoA hydratase
BS21228_04780	COG1309	transcriptional regulator
BS21228_04785	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_04790	COG3766	membrane
BS21228_04795	COG1193	negative regulation of DNA recombination
BS21228_04800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BS21228_04800	COG1796	DNA polymerase
BS21228_04805	COG1286	toxin biosynthetic process
BS21228_04810	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BS21228_04815	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BS21228_04820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS21228_04820	COG0072	phenylalanine-tRNA ligase activity
BS21228_04825	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BS21228_04835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS21228_04845	COG3835	regulator
BS21228_04850	COG0277	FAD linked oxidase domain protein
BS21228_04855	COG0247	lactate metabolic process
BS21228_04860	COG0346	lactoylglutathione lyase activity
BS21228_04865	COG1966	Carbon starvation protein
BS21228_04870	COG3534	alpha-L-arabinofuranosidase
BS21228_04875	COG0395	ABC-type sugar transport system, permease component
BS21228_04880	COG1175	transmembrane transport
BS21228_04885	COG1653	transport
BS21228_04890	COG0371	Dehydrogenase
BS21228_04895	COG0647	UMP catabolic process
BS21228_04900	COG0235	Class ii aldolase
BS21228_04905	COG1069	ribulokinase activity
BS21228_04910	COG2160	L-arabinose isomerase activity
BS21228_04920	COG1363	Peptidase, m42
BS21228_04930	COG3326	Membrane
BS21228_04935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BS21228_04940	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BS21228_04945	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BS21228_04955	COG1346	cytolysis
BS21228_04960	COG1380	Effector of murein hydrolase LrgA
BS21228_04965	COG3279	Response regulator of the LytR AlgR family
BS21228_04970	COG3275	phosphorelay sensor kinase activity
BS21228_04980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS21228_04990	COG0398	Pfam SNARE associated Golgi protein
BS21228_04995	COG1484	DNA-dependent DNA replication
BS21228_05000	COG3611	Membrane attachment protein
BS21228_05005	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BS21228_05010	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BS21228_05015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BS21228_05020	COG1733	regulation of RNA biosynthetic process
BS21228_05025	COG2814	Major facilitator Superfamily
BS21228_05030	COG0656	L-ascorbic acid biosynthetic process
BS21228_05035	COG0237	dephospho-CoA kinase activity
BS21228_05040	COG1971	Probably functions as a manganese efflux pump
BS21228_05045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BS21228_05050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS21228_05050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS21228_05055	COG5002	protein histidine kinase activity
BS21228_05060	COG0745	RESPONSE REGULATOR receiver
BS21228_05065	COG0039	L-malate dehydrogenase activity
BS21228_05070	COG0538	isocitrate dehydrogenase activity
BS21228_05075	COG0372	Belongs to the citrate synthase family
BS21228_05080	COG2707	UPF0756 membrane protein
BS21228_05085	COG0628	permease
BS21228_05090	COG3030	protein affecting phage T7 exclusion by the F plasmid
BS21228_05095	COG0469	pyruvate kinase activity
BS21228_05100	COG0205	6-phosphofructokinase activity
BS21228_05105	COG0825	malonyl-CoA metabolic process
BS21228_05110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BS21228_05115	COG0281	malic enzyme
BS21228_05120	COG0587	DNA-directed DNA polymerase activity
BS21228_05140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BS21228_05150	COG4109	DRTGG domain
BS21228_05160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BS21228_05165	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_05175	COG0165	Argininosuccinate lyase
BS21228_05180	COG0137	argininosuccinate synthase activity
BS21228_05185	COG0521	Mo-molybdopterin cofactor biosynthetic process
BS21228_05190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BS21228_05200	COG0827	DNA restriction-modification system
BS21228_05205	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BS21228_05210	COG3874	Sporulation protein YtfJ
BS21228_05220	COG1714	RDD family
BS21228_05225	COG0616	signal peptide processing
BS21228_05230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BS21228_05235	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BS21228_05240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS21228_05250	COG0301	tRNA thio-modification
BS21228_05255	COG1104	cysteine desulfurase activity
BS21228_05260	COG1114	Component of the transport system for branched-chain amino acids
BS21228_05265	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BS21228_05270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BS21228_05275	COG1309	transcriptional regulator
BS21228_05280	COG1956	GAF domain-containing protein
BS21228_05285	COG2199	diguanylate cyclase activity
BS21228_05285	COG2203	Gaf domain
BS21228_05295	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BS21228_05300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BS21228_05310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS21228_05315	COG0454	-acetyltransferase
BS21228_05320	COG0517	IMP dehydrogenase activity
BS21228_05325	COG0123	including yeast histone deacetylase and acetoin utilization protein
BS21228_05330	COG1360	Flagellar Motor Protein
BS21228_05335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BS21228_05340	COG1609	Transcriptional regulator
BS21228_05345	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BS21228_05345	COG1605	Chorismate mutase
BS21228_05350	COG3118	belongs to the thioredoxin family
BS21228_05355	COG4980	gas vesicle protein
BS21228_05360	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BS21228_05365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BS21228_05370	COG1674	ftsk spoiiie
BS21228_05375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS21228_05380	COG4848	Belongs to the UPF0354 family
BS21228_05385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_05395	COG1363	Peptidase, m42
BS21228_05400	COG5584	Small secreted protein
BS21228_05405	COG0281	malic enzyme
BS21228_05410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_05415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BS21228_05425	COG0510	thiamine kinase activity
BS21228_05430	COG1523	belongs to the glycosyl hydrolase 13 family
BS21228_05435	COG1597	lipid kinase activity
BS21228_05445	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BS21228_05450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS21228_05455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS21228_05460	COG2252	PERMEase
BS21228_05465	COG4473	ABC transporter
BS21228_05470	COG1131	(ABC) transporter
BS21228_05475	COG1349	DNA-binding transcription factor activity
BS21228_05480	COG1187	pseudouridine synthase activity
BS21228_05485	COG2244	polysaccharide biosynthetic process
BS21228_05490	COG2081	HI0933 family
BS21228_05495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BS21228_05515	COG1653	transport
BS21228_05520	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS21228_05525	COG4209	transmembrane transport
BS21228_05535	COG1653	transport
BS21228_05540	COG0395	ABC-type sugar transport system, permease component
BS21228_05545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS21228_05550	COG2124	cytochrome p450
BS21228_05570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS21228_05575	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BS21228_05580	COG1073	alpha beta
BS21228_05605	COG1486	melibiose metabolic process
BS21228_05610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS21228_05615	COG0495	leucyl-tRNA aminoacylation
BS21228_05625	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_05625	COG2202	Pas domain
BS21228_05630	COG2814	Major facilitator Superfamily
BS21228_05635	COG2433	Pfam Transposase IS66
BS21228_05640	COG0577	efflux transmembrane transporter activity
BS21228_05645	COG1136	(ABC) transporter
BS21228_05650	COG2205	protein histidine kinase activity
BS21228_05655	COG0745	RESPONSE REGULATOR receiver
BS21228_05660	COG0577	efflux transmembrane transporter activity
BS21228_05665	COG1136	(ABC) transporter
BS21228_05680	COG1131	(ABC) transporter
BS21228_05685	COG1725	Transcriptional regulator
BS21228_05695	COG1242	4 iron, 4 sulfur cluster binding
BS21228_05700	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BS21228_05710	COG2267	carboxylic ester hydrolase activity
BS21228_05715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BS21228_05720	COG1113	amino acid transport
BS21228_05725	COG0367	asparagine synthase
BS21228_05730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BS21228_05735	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BS21228_05745	COG1506	peptidase
BS21228_05750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS21228_05755	COG1116	anion transmembrane transporter activity
BS21228_05760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS21228_05765	COG0494	nUDIX hydrolase
BS21228_05770	COG4824	toxin secretion phage lysis holin
BS21228_05775	COG0783	Belongs to the Dps family
BS21228_05790	COG1854	S-ribosylhomocysteine lyase activity
BS21228_05795	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BS21228_05800	COG0288	reversible hydration of carbon dioxide
BS21228_05805	COG0254	rRNA binding
BS21228_05810	COG1271	oxidase subunit
BS21228_05815	COG1294	oxidase, subunit
BS21228_05825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS21228_05830	COG1321	iron dependent repressor
BS21228_05830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS21228_05835	COG1121	(ABC) transporter
BS21228_05840	COG0803	Belongs to the bacterial solute-binding protein 9 family
BS21228_05845	COG4948	Mandelate Racemase Muconate Lactonizing
BS21228_05850	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_05855	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BS21228_05860	COG0596	Alpha beta hydrolase
BS21228_05865	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BS21228_05870	COG1169	isochorismate synthase
BS21228_05875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS21228_05880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS21228_05885	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS21228_05890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS21228_05895	COG0438	transferase activity, transferring glycosyl groups
BS21228_05905	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS21228_05910	COG0438	transferase activity, transferring glycosyl groups
BS21228_05915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS21228_05920	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BS21228_05925	COG0058	SHG alpha-glucan phosphorylase activity
BS21228_05930	COG0297	glycogen (starch) synthase activity
BS21228_05935	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS21228_05940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS21228_05945	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BS21228_06070	COG3859	Proton-coupled thiamine transporter YuaJ
BS21228_06075	COG1247	-acetyltransferase
BS21228_06080	COG2268	Band 7 protein
BS21228_06085	COG1585	Membrane protein implicated in regulation of membrane protease activity
BS21228_06090	COG2318	DinB family
BS21228_06100	COG1454	alcohol dehydrogenase
BS21228_06110	COG1510	regulation of RNA biosynthetic process
BS21228_06120	COG0569	domain protein
BS21228_06125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS21228_06130	COG4682	membrane
BS21228_06135	COG1705	Flagellar rod assembly protein muramidase FlgJ
BS21228_06140	COG0477	Major facilitator Superfamily
BS21228_06145	COG5553	Cysteine dioxygenase type I
BS21228_06155	COG1968	undecaprenyl-diphosphatase activity
BS21228_06160	COG0628	permease
BS21228_06165	COG0673	inositol 2-dehydrogenase activity
BS21228_06170	COG4806	L-rhamnose isomerase
BS21228_06175	COG3254	rhamnose metabolic process
BS21228_06180	COG1070	Carbohydrate kinase
BS21228_06185	COG1349	DNA-binding transcription factor activity
BS21228_06190	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_06190	COG3347	Dehydrogenase
BS21228_06205	COG0840	transmembrane signaling receptor activity
BS21228_06215	COG0840	transmembrane signaling receptor activity
BS21228_06230	COG0432	Pfam Uncharacterised protein family UPF0047
BS21228_06235	COG0366	Alpha amylase catalytic
BS21228_06240	COG1253	flavin adenine dinucleotide binding
BS21228_06245	COG2738	Putative neutral zinc metallopeptidase
BS21228_06260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BS21228_06275	COG0166	Belongs to the GPI family
BS21228_06280	COG1979	alcohol dehydrogenase
BS21228_06285	COG1979	alcohol dehydrogenase
BS21228_06290	COG2155	Conserved Protein
BS21228_06295	COG1098	S1 RNA binding domain
BS21228_06300	COG0436	Aminotransferase
BS21228_06305	COG1522	sequence-specific DNA binding
BS21228_06310	COG2267	carboxylic ester hydrolase activity
BS21228_06320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BS21228_06325	COG2205	protein histidine kinase activity
BS21228_06335	COG5018	Exonuclease
BS21228_06345	COG2814	Major facilitator Superfamily
BS21228_06350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS21228_06355	COG3011	Protein conserved in bacteria
BS21228_06365	COG3290	protein histidine kinase activity
BS21228_06370	COG4565	transcriptional regulatory protein
BS21228_06395	COG3493	citrate carrier protein
BS21228_06405	COG2111	Na H antiporter
BS21228_06405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS21228_06410	COG2111	Na H antiporter
BS21228_06415	COG1006	Multisubunit Na H antiporter MnhC subunit
BS21228_06420	COG0651	ATP synthesis coupled electron transport
BS21228_06425	COG1863	multisubunit Na H antiporter MnhE subunit
BS21228_06430	COG2212	antiporter activity
BS21228_06435	COG1320	monovalent cation:proton antiporter activity
BS21228_06440	COG2050	protein possibly involved in aromatic compounds catabolism
BS21228_06445	COG2197	response regulator
BS21228_06450	COG4585	Histidine kinase
BS21228_06460	COG0142	geranyltranstransferase activity
BS21228_06475	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BS21228_06480	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BS21228_06485	COG1335	isochorismatase
BS21228_06490	COG5506	Protein of unknown function (DUF1694)
BS21228_06505	COG0628	permease
BS21228_06520	COG1418	mRNA catabolic process
BS21228_06525	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_06535	COG1511	domain protein
BS21228_06540	COG0433	COG0433 Predicted ATPase
BS21228_06540	COG1674	ftsk spoiiie
BS21228_06545	COG4499	WXG100 protein secretion system (Wss), protein YukC
BS21228_06550	COG5417	Belongs to the EsaB family
BS21228_06555	COG4842	Belongs to the WXG100 family
BS21228_06565	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BS21228_06565	COG2508	Transcriptional regulator
BS21228_06570	COG0686	Belongs to the AlaDH PNT family
BS21228_06575	COG5634	Uncharacterized conserved protein (DUF2278)
BS21228_06580	COG3251	PFAM MbtH domain protein
BS21228_06585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_06590	COG1535	isochorismatase
BS21228_06590	COG3433	isochorismatase activity
BS21228_06595	COG1021	2,3-dihydroxybenzoate-AMP ligase
BS21228_06600	COG1169	isochorismate synthase
BS21228_06605	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_06610	COG2819	hydrolase of the alpha beta superfamily
BS21228_06615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BS21228_06620	COG1268	BioY protein
BS21228_06625	COG2056	Na+-H+ antiporter family
BS21228_06630	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BS21228_06635	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BS21228_06640	COG3584	3D domain protein
BS21228_06655	COG1252	NADH dehydrogenase
BS21228_06660	COG0492	ferredoxin-NADP+ reductase activity
BS21228_06670	COG0516	GMP reductase activity
BS21228_06675	COG2808	Putative FMN-binding domain
BS21228_06680	COG0456	acetyltransferase
BS21228_06775	COG0582	viral genome integration into host DNA
BS21228_06785	COG4974	Belongs to the 'phage' integrase family
BS21228_06790	COG0316	Belongs to the HesB IscA family
BS21228_06795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BS21228_06800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS21228_06805	COG4844	belongs to the
BS21228_06810	COG1252	NADH dehydrogenase
BS21228_06815	COG4837	Protein of unknown function (DUF1462)
BS21228_06820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BS21228_06825	COG0823	Involved in the tonB-independent uptake of proteins
BS21228_06825	COG4946	Tricorn protease homolog
BS21228_06825	COG1506	peptidase
BS21228_06830	COG0083	homoserine kinase activity
BS21228_06835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BS21228_06840	COG0460	homoserine dehydrogenase
BS21228_06845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS21228_06850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS21228_06855	COG0647	UMP catabolic process
BS21228_06860	COG2445	Protein of unknown function DUF86
BS21228_06865	COG4470	Protein conserved in bacteria
BS21228_06875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BS21228_06880	COG0739	heme binding
BS21228_06890	COG3377	Domain of unknown function (DUF1805)
BS21228_06895	COG0737	Belongs to the 5'-nucleotidase family
BS21228_06900	COG0730	response to heat
BS21228_06905	COG1801	Protein of unknown function DUF72
BS21228_06915	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BS21228_06920	COG2508	Transcriptional regulator
BS21228_06925	COG2233	PERMEase
BS21228_06930	COG2233	PERMEase
BS21228_06935	COG3195	allantoin biosynthetic process
BS21228_06935	COG3648	Uricase
BS21228_06940	COG2351	hydroxyisourate hydrolase activity
BS21228_06950	COG2080	2 iron, 2 sulfur cluster binding
BS21228_06955	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BS21228_06960	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BS21228_06965	COG2068	MobA-Related Protein
BS21228_06970	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BS21228_06975	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BS21228_06980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS21228_06985	COG2356	endonuclease I
BS21228_06990	COG3842	ATPase activity
BS21228_06995	COG2188	Transcriptional regulator
BS21228_07000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS21228_07010	COG1175	transmembrane transport
BS21228_07015	COG1653	transport
BS21228_07020	COG2222	sugar isomerase
BS21228_07025	COG0322	excinuclease ABC activity
BS21228_07030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS21228_07045	COG0346	lactoylglutathione lyase activity
BS21228_07050	COG0640	Transcriptional regulator
BS21228_07055	COG0719	Fe-S assembly protein
BS21228_07060	COG0822	iron-sulfur transferase activity
BS21228_07065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BS21228_07070	COG0719	Fe-S assembly protein
BS21228_07075	COG0396	ATPase activity
BS21228_07095	COG1464	Belongs to the NlpA lipoprotein family
BS21228_07100	COG2011	ABC-type metal ion transport system permease component
BS21228_07105	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS21228_07115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_07120	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BS21228_07130	COG0509	glycine decarboxylation via glycine cleavage system
BS21228_07135	COG1393	Belongs to the ArsC family
BS21228_07140	COG1960	acyl-CoA dehydrogenase activity
BS21228_07145	COG0183	Belongs to the thiolase family
BS21228_07150	COG1024	Enoyl-CoA hydratase
BS21228_07150	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS21228_07170	COG5577	PFAM Coat F domain
BS21228_07175	COG1846	Transcriptional regulator
BS21228_07180	COG0477	Major facilitator Superfamily
BS21228_07185	COG1942	4-Oxalocrotonate Tautomerase
BS21228_07190	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_07195	COG0583	DNA-binding transcription factor activity
BS21228_07205	COG1120	ATPase activity
BS21228_07225	COG1131	(ABC) transporter
BS21228_07275	COG0783	Belongs to the Dps family
BS21228_07280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS21228_07285	COG0745	RESPONSE REGULATOR receiver
BS21228_07290	COG2770	Histidine kinase
BS21228_07290	COG2205	protein histidine kinase activity
BS21228_07300	COG1309	transcriptional regulator
BS21228_07305	COG0114	fumarate hydratase activity
BS21228_07315	COG0697	spore germination
BS21228_07320	COG0814	amino acid
BS21228_07330	COG2197	response regulator
BS21228_07335	COG4585	Histidine kinase
BS21228_07340	COG4758	membrane
BS21228_07345	COG3595	metallopeptidase activity
BS21228_07350	COG1842	Phage shock protein A
BS21228_07355	COG4758	membrane
BS21228_07360	COG2814	Major facilitator Superfamily
BS21228_07365	COG2096	Adenosyltransferase
BS21228_07370	COG1120	ATPase activity
BS21228_07375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_07380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_07385	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_07390	COG3386	PFAM SMP-30 Gluconolaconase
BS21228_07395	COG2205	protein histidine kinase activity
BS21228_07400	COG0745	RESPONSE REGULATOR receiver
BS21228_07420	COG2140	Oxalate decarboxylase
BS21228_07430	COG0577	efflux transmembrane transporter activity
BS21228_07435	COG1136	(ABC) transporter
BS21228_07440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS21228_07445	COG1120	ATPase activity
BS21228_07450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_07455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_07460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_07470	COG0531	amino acid
BS21228_07485	COG1988	membrane-bound metal-dependent
BS21228_07490	COG1368	sulfuric ester hydrolase activity
BS21228_07495	COG1910	domain protein
BS21228_07500	COG0725	ABC transporter, periplasmic molybdate-binding protein
BS21228_07505	COG4149	molybdate abc transporter
BS21228_07510	COG0656	L-ascorbic acid biosynthetic process
BS21228_07520	COG0025	NhaP-type Na H and K H
BS21228_07525	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS21228_07530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BS21228_07535	COG3973	AAA domain
BS21228_07545	COG2860	membrane
BS21228_07550	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BS21228_07555	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BS21228_07560	COG2217	Heavy metal translocating P-type atpase
BS21228_07565	COG2217	Heavy metal translocating P-type atpase
BS21228_07570	COG2608	mercury ion transmembrane transporter activity
BS21228_07575	COG1937	Protein conserved in bacteria
BS21228_07580	COG0673	inositol 2-dehydrogenase activity
BS21228_07590	COG1289	transmembrane transporter activity
BS21228_07600	COG2076	Multidrug Resistance protein
BS21228_07605	COG1309	transcriptional regulator
BS21228_07610	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_07620	COG5444	nuclease activity
BS21228_07635	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_07635	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_07640	COG4824	toxin secretion phage lysis holin
BS21228_07665	COG3942	CHAP domain
BS21228_07665	COG1705	Flagellar rod assembly protein muramidase FlgJ
BS21228_07890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BS21228_07895	COG0557	exoribonuclease II activity
BS21228_07900	COG1647	Serine aminopeptidase, S33
BS21228_07905	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS21228_07910	COG0596	Alpha beta hydrolase
BS21228_07915	COG1476	TRANSCRIPTIONal
BS21228_07920	COG1396	sequence-specific DNA binding
BS21228_07925	COG1396	sequence-specific DNA binding
BS21228_07930	COG1733	regulation of RNA biosynthetic process
BS21228_07935	COG0840	transmembrane signaling receptor activity
BS21228_07940	COG1174	glycine betaine transport
BS21228_07945	COG1732	Glycine betaine
BS21228_07950	COG1174	glycine betaine transport
BS21228_07955	COG1125	glycine betaine transport
BS21228_07955	COG0517	IMP dehydrogenase activity
BS21228_07960	COG1510	regulation of RNA biosynthetic process
BS21228_07965	COG1174	glycine betaine transport
BS21228_07970	COG1732	Glycine betaine
BS21228_07975	COG1174	glycine betaine transport
BS21228_07980	COG1125	glycine betaine transport
BS21228_07980	COG0517	IMP dehydrogenase activity
BS21228_07985	COG1510	regulation of RNA biosynthetic process
BS21228_07990	COG2095	MarC family integral membrane protein
BS21228_08000	COG3064	Membrane
BS21228_08005	COG4640	response to antibiotic
BS21228_08010	COG0456	acetyltransferase
BS21228_08015	COG0148	phosphopyruvate hydratase activity
BS21228_08020	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BS21228_08025	COG0149	triose-phosphate isomerase activity
BS21228_08030	COG0126	phosphoglycerate kinase activity
BS21228_08035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BS21228_08040	COG2390	Transcriptional regulator
BS21228_08045	COG2814	Major facilitator Superfamily
BS21228_08050	COG1609	Transcriptional regulator
BS21228_08055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS21228_08065	COG0583	DNA-binding transcription factor activity
BS21228_08070	COG0697	spore germination
BS21228_08075	COG1113	amino acid transport
BS21228_08085	COG1556	Lactate utilization protein
BS21228_08090	COG1139	Iron-sulfur cluster binding protein
BS21228_08095	COG0247	lactate metabolic process
BS21228_08100	COG2197	response regulator
BS21228_08105	COG4585	Histidine kinase
BS21228_08110	COG0842	Transport permease protein
BS21228_08115	COG1131	(ABC) transporter
BS21228_08135	COG0596	Alpha beta hydrolase
BS21228_08140	COG2208	phosphoserine phosphatase activity
BS21228_08145	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BS21228_08150	COG1874	Beta-galactosidase
BS21228_08155	COG3833	ABC-type maltose transport systems, permease component
BS21228_08160	COG1175	transmembrane transport
BS21228_08165	COG2182	Extracellular solute-binding protein
BS21228_08170	COG1609	Transcriptional regulator
BS21228_08175	COG2186	Transcriptional regulator
BS21228_08180	COG1620	l-lactate permease
BS21228_08185	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BS21228_08195	COG5039	Polysaccharide pyruvyl transferase
BS21228_08200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS21228_08205	COG0110	maltose O-acetyltransferase activity
BS21228_08210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BS21228_08215	COG2244	polysaccharide biosynthetic process
BS21228_08220	COG1216	Glycosyl transferase, family 2
BS21228_08225	COG5039	Polysaccharide pyruvyl transferase
BS21228_08230	COG1216	Glycosyl transferase, family 2
BS21228_08240	COG0438	transferase activity, transferring glycosyl groups
BS21228_08245	COG1215	transferase activity, transferring glycosyl groups
BS21228_08255	COG1086	Polysaccharide biosynthesis protein
BS21228_08260	COG0489	protein tyrosine kinase activity
BS21228_08265	COG3944	biosynthesis protein
BS21228_08270	COG1396	sequence-specific DNA binding
BS21228_08275	COG2272	Belongs to the type-B carboxylesterase lipase family
BS21228_08285	COG3479	Phenolic acid decarboxylase
BS21228_08300	COG1794	racemase activity, acting on amino acids and derivatives
BS21228_08310	COG1621	beta-fructofuranosidase activity
BS21228_08315	COG1621	beta-fructofuranosidase activity
BS21228_08320	COG0531	amino acid
BS21228_08325	COG1309	transcriptional regulator
BS21228_08330	COG2076	Multidrug Resistance protein
BS21228_08335	COG2076	Multidrug Resistance protein
BS21228_08355	COG1674	ftsk spoiiie
BS21228_08375	COG1388	LysM domain
BS21228_08375	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_08375	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_08410	COG1705	Flagellar rod assembly protein muramidase FlgJ
BS21228_08490	COG0582	viral genome integration into host DNA
BS21228_08590	COG4974	Belongs to the 'phage' integrase family
BS21228_08600	COG0740	serine-type endopeptidase activity
BS21228_08605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS21228_08610	COG0366	Alpha amylase catalytic
BS21228_08615	COG1554	hydrolase, family 65, central catalytic
BS21228_08620	COG5521	maltodextrose utilization protein MalA
BS21228_08625	COG3833	ABC-type maltose transport systems, permease component
BS21228_08630	COG1175	transmembrane transport
BS21228_08635	COG2182	Extracellular solute-binding protein
BS21228_08645	COG1609	Transcriptional regulator
BS21228_08650	COG1611	Belongs to the LOG family
BS21228_08660	COG0659	secondary active sulfate transmembrane transporter activity
BS21228_08665	COG0288	reversible hydration of carbon dioxide
BS21228_08670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS21228_08675	COG0577	efflux transmembrane transporter activity
BS21228_08680	COG1136	(ABC) transporter
BS21228_08685	COG5002	protein histidine kinase activity
BS21228_08690	COG0745	RESPONSE REGULATOR receiver
BS21228_08700	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BS21228_08705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_08710	COG1481	regulation of sporulation
BS21228_08715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BS21228_08720	COG1660	Displays ATPase and GTPase activities
BS21228_08725	COG1051	belongs to the nudix hydrolase family
BS21228_08730	COG0492	ferredoxin-NADP+ reductase activity
BS21228_08740	COG0457	Tetratricopeptide repeat
BS21228_08745	COG1132	(ABC) transporter
BS21228_08765	COG0140	phosphoribosyl-ATP diphosphatase activity
BS21228_08765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BS21228_08770	COG0107	imidazoleglycerol-phosphate synthase activity
BS21228_08775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BS21228_08780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BS21228_08785	COG0131	Imidazoleglycerol-phosphate dehydratase
BS21228_08790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BS21228_08795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BS21228_08800	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BS21228_08805	COG4990	cell redox homeostasis
BS21228_08810	COG5297	Belongs to the glycosyl hydrolase family 6
BS21228_08825	COG0546	phosphoglycolate phosphatase activity
BS21228_08830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BS21228_08835	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BS21228_08840	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BS21228_08845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BS21228_08850	COG0363	glucosamine-6-phosphate deaminase activity
BS21228_08860	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BS21228_08875	COG1950	PFAM Membrane protein of
BS21228_08880	COG1983	PspC domain protein
BS21228_08885	COG3595	metallopeptidase activity
BS21228_08900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS21228_08905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BS21228_08910	COG0556	nucleotide-excision repair
BS21228_08915	COG4897	Protein conserved in bacteria
BS21228_08920	COG3848	Pyruvate phosphate dikinase
BS21228_08920	COG0574	Belongs to the PEP-utilizing enzyme family
BS21228_08925	COG1309	transcriptional regulator
BS21228_08930	COG2814	Major facilitator Superfamily
BS21228_08935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS21228_08945	COG0793	Belongs to the peptidase S41A family
BS21228_08945	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_08950	COG2177	Part of the ABC transporter FtsEX involved in
BS21228_08955	COG2884	Cell division ATP-binding protein ftsE
BS21228_08960	COG2010	Cytochrome c
BS21228_08965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_08975	COG0653	protein targeting
BS21228_08980	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BS21228_08995	COG1516	flagellar protein fliS
BS21228_09000	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BS21228_09005	COG1334	flagellar protein FlaG
BS21228_09010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS21228_09015	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BS21228_09020	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BS21228_09030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS21228_09035	COG4786	Flagellar basal body rod
BS21228_09035	COG1256	bacterial-type flagellum assembly
BS21228_09040	COG3418	PFAM FlgN family protein
BS21228_09045	COG2747	anti-sigma28 factor FlgM
BS21228_09055	COG1040	competence protein
BS21228_09065	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BS21228_09070	COG1307	EDD domain protein, DegV family
BS21228_09075	COG2197	response regulator
BS21228_09080	COG4585	Histidine kinase
BS21228_09085	COG1739	Uncharacterized protein family UPF0029
BS21228_09090	COG1316	TRANSCRIPTIONal
BS21228_09125	COG1131	(ABC) transporter
BS21228_09135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS21228_09140	COG0438	transferase activity, transferring glycosyl groups
BS21228_09145	COG1215	transferase activity, transferring glycosyl groups
BS21228_09150	COG3206	protein involved in exopolysaccharide biosynthesis
BS21228_09155	COG3307	-O-antigen
BS21228_09165	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS21228_09170	COG0438	transferase activity, transferring glycosyl groups
BS21228_09170	COG0297	glycogen (starch) synthase activity
BS21228_09175	COG2244	polysaccharide biosynthetic process
BS21228_09190	COG2247	cell wall binding repeat
BS21228_09190	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_09195	COG2247	cell wall binding repeat
BS21228_09195	COG2385	sporulation resulting in formation of a cellular spore
BS21228_09225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BS21228_09230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS21228_09240	COG1134	teichoic acid transport
BS21228_09245	COG1682	transport, permease protein
BS21228_09260	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS21228_09260	COG0463	Glycosyl transferase, family 2
BS21228_09265	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS21228_09270	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BS21228_09275	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BS21228_09280	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS21228_09285	COG4193	domain, Protein
BS21228_09290	COG1482	cell wall glycoprotein biosynthetic process
BS21228_09295	COG0697	spore germination
BS21228_09300	COG0814	amino acid
BS21228_09315	COG1316	TRANSCRIPTIONal
BS21228_09320	COG0561	phosphatase activity
BS21228_09325	COG0791	NLP P60 protein
BS21228_09335	COG2843	Capsule synthesis protein
BS21228_09345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BS21228_09355	COG1609	Transcriptional regulator
BS21228_09360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS21228_09365	COG1869	D-ribose catabolic process
BS21228_09370	COG1129	ABC transporter
BS21228_09375	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS21228_09380	COG1879	ABC-type sugar transport system periplasmic component
BS21228_09385	COG3103	Sh3 type 3 domain protein
BS21228_09395	COG2249	NAD(P)H dehydrogenase (quinone) activity
BS21228_09400	COG3527	Alpha-acetolactate decarboxylase
BS21228_09405	COG0028	Belongs to the TPP enzyme family
BS21228_09410	COG0583	DNA-binding transcription factor activity
BS21228_09415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS21228_09430	COG5337	Spore coat protein CotH
BS21228_09440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS21228_09450	COG0405	Gamma-glutamyltransferase
BS21228_09455	COG1522	sequence-specific DNA binding
BS21228_09460	COG2059	Chromate
BS21228_09465	COG2059	Chromate
BS21228_09475	COG0655	NAD(P)H dehydrogenase (quinone) activity
BS21228_09480	COG0583	DNA-binding transcription factor activity
BS21228_09510	COG5444	nuclease activity
BS21228_09530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS21228_09535	COG4464	protein tyrosine phosphatase activity
BS21228_09540	COG0489	protein tyrosine kinase activity
BS21228_09545	COG3944	biosynthesis protein
BS21228_09555	COG4715	Zinc finger, swim domain protein
BS21228_09560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS21228_09570	COG0561	phosphatase activity
BS21228_09575	COG1349	DNA-binding transcription factor activity
BS21228_09580	COG0629	single-stranded DNA binding
BS21228_09595	COG3764	Sortase (surface protein transpeptidase)
BS21228_09600	COG2972	Histidine kinase
BS21228_09600	COG0745	RESPONSE REGULATOR receiver
BS21228_09605	COG1970	mechanosensitive ion channel activity
BS21228_09610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BS21228_09615	COG0457	Tetratricopeptide repeat
BS21228_09620	COG4786	Flagellar basal body rod
BS21228_09625	COG4786	Flagellar basal body rod
BS21228_09630	COG1077	Cell shape determining protein MreB Mrl
BS21228_09635	COG1609	Transcriptional regulator
BS21228_09645	COG1846	Transcriptional regulator
BS21228_09650	COG2814	Major facilitator Superfamily
BS21228_09655	COG3420	alginic acid biosynthetic process
BS21228_09660	COG1953	Uracil, thiamine, allantoin
BS21228_09665	COG0477	Major facilitator Superfamily
BS21228_09670	COG1335	isochorismatase
BS21228_09680	COG0004	ammonium transporteR
BS21228_09685	COG0347	Belongs to the P(II) protein family
BS21228_09690	COG0671	phosphoesterase, PA-phosphatase related
BS21228_09700	COG0739	heme binding
BS21228_09705	COG1247	-acetyltransferase
BS21228_09715	COG2089	acid synthase
BS21228_09725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS21228_09730	COG0789	Transcriptional regulator
BS21228_09740	COG2910	NAD(P)H-binding
BS21228_09745	COG1959	2 iron, 2 sulfur cluster binding
BS21228_09750	COG0804	urea catabolic process
BS21228_09755	COG0832	Belongs to the urease beta subunit family
BS21228_09760	COG0831	urea catabolic process
BS21228_09775	COG3237	CsbD-like
BS21228_09780	COG1994	Peptidase M50
BS21228_09785	COG0457	Tetratricopeptide repeat
BS21228_09795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BS21228_09800	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BS21228_09810	COG2304	oxidoreductase activity
BS21228_09820	COG2304	oxidoreductase activity
BS21228_09825	COG2385	sporulation resulting in formation of a cellular spore
BS21228_09830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BS21228_09840	COG4836	Membrane
BS21228_09850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BS21228_09855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BS21228_09860	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BS21228_09865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BS21228_09870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BS21228_09875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BS21228_09880	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BS21228_09885	COG0356	it plays a direct role in the translocation of protons across the membrane
BS21228_09895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BS21228_09900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BS21228_09905	COG4475	Protein of unknown function (DUF436)
BS21228_09910	COG0698	ribose 5-phosphate isomerase
BS21228_09915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS21228_09920	COG1971	Probably functions as a manganese efflux pump
BS21228_09925	COG0009	L-threonylcarbamoyladenylate synthase
BS21228_09930	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BS21228_09950	COG2890	protein-(glutamine-N5) methyltransferase activity
BS21228_09955	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BS21228_09960	COG0346	lactoylglutathione lyase activity
BS21228_09965	COG0789	Transcriptional regulator
BS21228_09970	COG0679	Auxin Efflux Carrier
BS21228_09975	COG0281	malic enzyme
BS21228_09980	COG1435	thymidine kinase activity
BS21228_09985	COG0254	rRNA binding
BS21228_09990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BS21228_09995	COG1494	fructose-1,6-bisphosphatase
BS21228_10000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BS21228_10005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BS21228_10010	COG0191	fructose-bisphosphate aldolase activity
BS21228_10015	COG2204	response regulator
BS21228_10020	COG4821	SIS domain
BS21228_10025	COG0504	CTP synthase activity
BS21228_10030	COG3343	RNA polymerase activity
BS21228_10035	COG1960	acyl-CoA dehydrogenase activity
BS21228_10040	COG2181	nitrate reductase activity
BS21228_10040	COG0247	lactate metabolic process
BS21228_10045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS21228_10050	COG4294	response to UV
BS21228_10060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS21228_10070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS21228_10080	COG2181	nitrate reductase activity
BS21228_10085	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BS21228_10090	COG1140	nitrate reductase beta subunit
BS21228_10095	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BS21228_10100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS21228_10110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS21228_10115	COG2223	nitrite transmembrane transporter activity
BS21228_10120	COG0018	arginyl-trna synthetase
BS21228_10125	COG4506	Protein conserved in bacteria
BS21228_10140	COG0535	radical SAM domain protein
BS21228_10150	COG1131	(ABC) transporter
BS21228_10155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BS21228_10160	COG0612	Peptidase, M16
BS21228_10165	COG0612	Peptidase, M16
BS21228_10175	COG3391	amine dehydrogenase activity
BS21228_10180	COG3391	amine dehydrogenase activity
BS21228_10190	COG0457	Tetratricopeptide repeat
BS21228_10205	COG0010	Belongs to the arginase family
BS21228_10210	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BS21228_10215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS21228_10230	COG1994	Peptidase M50
BS21228_10235	COG1942	4-Oxalocrotonate Tautomerase
BS21228_10240	COG1846	Transcriptional regulator
BS21228_10245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS21228_10250	COG0477	Major facilitator Superfamily
BS21228_10255	COG1959	2 iron, 2 sulfur cluster binding
BS21228_10260	COG3465	dGTPase activity
BS21228_10265	COG1078	dGTPase activity
BS21228_10270	COG4844	belongs to the
BS21228_10280	COG0697	spore germination
BS21228_10285	COG0095	Lipoate-protein ligase
BS21228_10290	COG0583	DNA-binding transcription factor activity
BS21228_10295	COG0280	phosphate acetyltransferase
BS21228_10305	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_10310	COG0436	Aminotransferase
BS21228_10315	COG2814	Major facilitator Superfamily
BS21228_10320	COG0151	Belongs to the GarS family
BS21228_10325	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_10330	COG1917	Cupin 2, conserved barrel domain protein
BS21228_10335	COG0077	Prephenate dehydratase
BS21228_10340	COG2814	Major facilitator Superfamily
BS21228_10345	COG0833	amino acid
BS21228_10350	COG4187	Peptidase family M20/M25/M40
BS21228_10355	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_10360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS21228_10370	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BS21228_10375	COG1091	dTDP-4-dehydrorhamnose reductase activity
BS21228_10380	COG1088	dTDP-glucose 4,6-dehydratase activity
BS21228_10385	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BS21228_10390	COG3980	spore coat polysaccharide biosynthesis protein
BS21228_10395	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BS21228_10400	COG2089	acid synthase
BS21228_10405	COG0456	acetyltransferase
BS21228_10410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS21228_10415	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS21228_10420	COG0463	Glycosyl transferase, family 2
BS21228_10435	COG2363	Small membrane protein
BS21228_10440	COG2233	PERMEase
BS21228_10450	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_10455	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BS21228_10460	COG1216	Glycosyl transferase, family 2
BS21228_10465	COG0351	phosphomethylpyrimidine kinase
BS21228_10475	COG1621	beta-fructofuranosidase activity
BS21228_10480	COG1263	PTS System
BS21228_10480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_10485	COG2116	formate transmembrane transporter activity
BS21228_10500	COG1404	Belongs to the peptidase S8 family
BS21228_10505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS21228_10510	COG0778	Nitroreductase
BS21228_10515	COG0772	Belongs to the SEDS family
BS21228_10530	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BS21228_10535	COG1845	cytochrome c oxidase, subunit III
BS21228_10540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BS21228_10545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS21228_10550	COG2261	transglycosylase associated protein
BS21228_10555	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BS21228_10560	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BS21228_10565	COG2246	polysaccharide biosynthetic process
BS21228_10570	COG1309	transcriptional regulator
BS21228_10580	COG3162	membrane
BS21228_10585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS21228_10590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BS21228_10595	COG2837	iron assimilation
BS21228_10600	COG2822	iron ion transport
BS21228_10605	COG0672	)-iron permease
BS21228_10610	COG0352	thiamine-phosphate diphosphorylase activity
BS21228_10615	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BS21228_10620	COG0583	DNA-binding transcription factor activity
BS21228_10625	COG1380	Effector of murein hydrolase LrgA
BS21228_10630	COG1346	cytolysis
BS21228_10635	COG2814	Major facilitator Superfamily
BS21228_10640	COG4895	conserved protein (DUF2196)
BS21228_10645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BS21228_10650	COG0346	lactoylglutathione lyase activity
BS21228_10660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS21228_10670	COG1263	PTS System
BS21228_10670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_10675	COG3711	transcriptional antiterminator
BS21228_10680	COG1442	glycosyl transferase family 8
BS21228_10685	COG5522	Integral membrane protein (intg_mem_TP0381)
BS21228_10690	COG1846	Transcriptional regulator
BS21228_10695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BS21228_10700	COG2234	aminopeptidase activity
BS21228_10705	COG2357	RelA SpoT domain protein
BS21228_10715	COG2801	Transposase and inactivated derivatives
BS21228_10720	COG1575	Belongs to the MenA family. Type 1 subfamily
BS21228_10735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_10740	COG1696	Membrane protein involved in D-alanine export
BS21228_10745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS21228_10750	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BS21228_10760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS21228_10765	COG1486	melibiose metabolic process
BS21228_10770	COG1447	Phosphotransferase system cellobiose-specific component IIA
BS21228_10775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS21228_10780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS21228_10785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_10785	COG3711	transcriptional antiterminator
BS21228_10795	COG2094	Belongs to the DNA glycosylase MPG family
BS21228_10800	COG0753	catalase activity
BS21228_10805	COG2814	Major facilitator Superfamily
BS21228_10810	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS21228_10815	COG1131	(ABC) transporter
BS21228_10835	COG1595	DNA-templated transcription, initiation
BS21228_10840	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS21228_10845	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BS21228_10850	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BS21228_10855	COG4988	ABC transporter
BS21228_10860	COG1294	oxidase, subunit
BS21228_10865	COG1271	oxidase subunit
BS21228_10870	COG3493	citrate carrier protein
BS21228_10875	COG0501	Belongs to the peptidase M48B family
BS21228_10885	COG0726	polysaccharide deacetylase
BS21228_10890	COG3842	ATPase activity
BS21228_10895	COG2508	Transcriptional regulator
BS21228_10900	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_10905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_10915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BS21228_10925	COG4585	Histidine kinase
BS21228_10930	COG2197	response regulator
BS21228_10935	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS21228_10945	COG4894	glucomannan catabolic process
BS21228_10950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS21228_10955	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS21228_10960	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_10965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS21228_10970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS21228_10975	COG2610	gluconate transmembrane transporter activity
BS21228_10980	COG0500	methyltransferase
BS21228_10985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS21228_11000	COG0693	protein deglycase activity
BS21228_11000	COG0753	catalase activity
BS21228_11005	COG2851	Citrate transporter
BS21228_11010	COG2273	Hydrolase Family 16
BS21228_11015	COG3711	transcriptional antiterminator
BS21228_11030	COG2270	Major facilitator Superfamily
BS21228_11035	COG0513	Belongs to the DEAD box helicase family
BS21228_11040	COG3401	FG-GAP repeat protein
BS21228_11040	COG2755	lipolytic protein G-D-S-L family
BS21228_11170	COG0589	response to stress
BS21228_11180	COG2190	(PTS) system
BS21228_11180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_11180	COG1263	PTS System
BS21228_11190	COG5444	nuclease activity
BS21228_11200	COG5444	nuclease activity
BS21228_11220	COG0494	nUDIX hydrolase
BS21228_11225	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BS21228_11230	COG3507	Belongs to the glycosyl hydrolase 43 family
BS21228_11235	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BS21228_11245	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BS21228_11250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS21228_11255	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BS21228_11260	COG2390	Transcriptional regulator
BS21228_11270	COG3192	ethanolamine utilization protein
BS21228_11275	COG2079	MmgE PrpD family protein
BS21228_11285	COG1126	abc transporter atp-binding protein
BS21228_11290	COG0765	amino acid transport
BS21228_11295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS21228_11310	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BS21228_11315	COG0561	phosphatase activity
BS21228_11345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_11350	COG5294	Protein conserved in bacteria
BS21228_11365	COG2205	protein histidine kinase activity
BS21228_11370	COG0745	RESPONSE REGULATOR receiver
BS21228_11375	COG0191	fructose-bisphosphate aldolase activity
BS21228_11380	COG1082	Xylose isomerase domain protein TIM barrel
BS21228_11385	COG1082	Xylose isomerase domain protein TIM barrel
BS21228_11390	COG0673	inositol 2-dehydrogenase activity
BS21228_11395	COG2814	Major facilitator Superfamily
BS21228_11400	COG1082	Xylose isomerase domain protein TIM barrel
BS21228_11405	COG3962	Belongs to the TPP enzyme family
BS21228_11410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS21228_11430	COG1349	DNA-binding transcription factor activity
BS21228_11435	COG0667	Aldo Keto reductase
BS21228_11465	COG0326	Molecular chaperone. Has ATPase activity
BS21228_11525	COG1917	Cupin 2, conserved barrel domain protein
BS21228_11530	COG1309	transcriptional regulator
BS21228_11535	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_11540	COG1846	Transcriptional regulator
BS21228_11545	COG1380	Effector of murein hydrolase LrgA
BS21228_11550	COG1346	cytolysis
BS21228_11555	COG5039	Polysaccharide pyruvyl transferase
BS21228_11560	COG1929	Belongs to the glycerate kinase type-1 family
BS21228_11565	COG1802	Transcriptional regulator
BS21228_11570	COG1070	Carbohydrate kinase
BS21228_11575	COG2610	gluconate transmembrane transporter activity
BS21228_11580	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BS21228_11585	COG0450	alkyl hydroperoxide reductase
BS21228_11590	COG3634	alkyl hydroperoxide reductase activity
BS21228_11595	COG2723	6-phospho-beta-galactosidase activity
BS21228_11610	COG2188	Transcriptional regulator
BS21228_11620	COG1131	(ABC) transporter
BS21228_11625	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BS21228_11640	COG0071	Belongs to the small heat shock protein (HSP20) family
BS21228_11650	COG3773	Cell wall hydrolase
BS21228_11675	COG0210	DNA helicase
BS21228_11705	COG2963	transposase activity
BS21228_11740	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BS21228_11755	COG1063	alcohol dehydrogenase
BS21228_11775	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BS21228_11780	COG0456	acetyltransferase
BS21228_11785	COG0457	Tetratricopeptide repeat
BS21228_11795	COG0010	Belongs to the arginase family
BS21228_11800	COG0833	amino acid
BS21228_11805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BS21228_11825	COG5658	integral membrane protein
BS21228_11830	COG0640	Transcriptional regulator
BS21228_11835	COG3829	transcription factor binding
BS21228_11840	COG5002	protein histidine kinase activity
BS21228_11845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS21228_11850	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BS21228_11855	COG4853	Protein conserved in bacteria
BS21228_11860	COG4863	YycH protein
BS21228_11865	COG5002	protein histidine kinase activity
BS21228_11870	COG0745	RESPONSE REGULATOR receiver
BS21228_11900	COG0346	lactoylglutathione lyase activity
BS21228_11905	COG0305	Participates in initiation and elongation during chromosome replication
BS21228_11920	COG3093	addiction module antidote protein HigA
BS21228_11925	COG2807	transmembrane transport
BS21228_11930	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BS21228_11935	COG0359	binds to the 23S rRNA
BS21228_11940	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BS21228_11945	COG4241	membrane
BS21228_11960	COG1733	regulation of RNA biosynthetic process
BS21228_11965	COG1227	inorganic diphosphatase activity
BS21228_11980	COG2271	Major facilitator Superfamily
BS21228_11985	COG4978	Transcriptional regulator
BS21228_11985	COG0789	Transcriptional regulator
BS21228_11995	COG4319	ketosteroid isomerase
BS21228_12000	COG1357	PFAM Pentapeptide repeats (8 copies)
BS21228_12015	COG1846	Transcriptional regulator
BS21228_12020	COG2153	protein acetylation
BS21228_12025	COG2364	Membrane
BS21228_12030	COG0456	acetyltransferase
BS21228_12035	COG2315	Protein conserved in bacteria
BS21228_12040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS21228_12045	COG1331	Highly conserved protein containing a thioredoxin domain
BS21228_12050	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BS21228_12055	COG1331	Highly conserved protein containing a thioredoxin domain
BS21228_12060	COG1266	CAAX protease self-immunity
BS21228_12065	COG2814	Major facilitator Superfamily
BS21228_12065	COG0477	Major facilitator Superfamily
BS21228_12070	COG0346	lactoylglutathione lyase activity
BS21228_12075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS21228_12080	COG0542	response to heat
BS21228_12095	COG0708	Exodeoxyribonuclease III
BS21228_12100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BS21228_12105	COG0629	single-stranded DNA binding
BS21228_12110	COG0360	Binds together with S18 to 16S ribosomal RNA
BS21228_12115	COG0012	GTP binding
BS21228_12120	COG0243	molybdopterin cofactor binding
BS21228_12125	COG4481	Protein conserved in bacteria
BS21228_12130	COG3949	Membrane
BS21228_12140	COG1475	DNA binding
BS21228_12145	COG1192	Involved in chromosome partitioning
BS21228_12155	COG1475	DNA binding
BS21228_12160	COG0357	Ribosomal RNA small subunit methyltransferase G
BS21228_12165	COG0445	tRNA wobble uridine modification
BS21228_12170	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BS21228_12175	COG1847	R3H domain protein
BS21228_12180	COG0706	membrane insertase activity
BS21228_12185	COG0594	ribonuclease P activity
BS21228_12190	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BS21228_12195	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BS21228_12200	COG0592	DNA-directed DNA polymerase activity
BS21228_12205	COG2501	S4 domain
BS21228_12210	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BS21228_12220	COG0187	DNA topoisomerase II activity
BS21228_12225	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS21228_12260	COG0516	GMP reductase activity
BS21228_12260	COG0517	IMP dehydrogenase activity
BS21228_12265	COG1686	Belongs to the peptidase S11 family
BS21228_12270	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BS21228_12275	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BS21228_12280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BS21228_12290	COG1428	Deoxynucleoside kinase
BS21228_12295	COG1428	Deoxynucleoside kinase
BS21228_12300	COG3858	chitin binding
BS21228_12300	COG1388	LysM domain
BS21228_12305	COG1335	isochorismatase
BS21228_12310	COG0590	tRNA wobble adenosine to inosine editing
BS21228_12320	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BS21228_12325	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BS21228_12330	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BS21228_12375	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BS21228_12380	COG3853	Toxic anion resistance protein (TelA)
BS21228_12385	COG1982	Orn Lys Arg decarboxylase major
BS21228_12390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BS21228_12395	COG3870	Protein conserved in bacteria
BS21228_12400	COG1728	Protein conserved in bacteria
BS21228_12405	COG0470	DNA polymerase III
BS21228_12410	COG1774	PSP1 C-terminal conserved region
BS21228_12415	COG4467	Involved in initiation control of chromosome replication
BS21228_12420	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BS21228_12425	COG2827	Endonuclease containing a URI domain
BS21228_12430	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BS21228_12435	COG2002	toxin-antitoxin pair type II binding
BS21228_12440	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS21228_12440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS21228_12445	COG0084	hydrolase, TatD family'
BS21228_12450	COG3583	domain protein
BS21228_12450	COG3584	3D domain protein
BS21228_12455	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BS21228_12460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BS21228_12470	COG4466	Protein conserved in bacteria
BS21228_12480	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BS21228_12485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS21228_12490	COG0251	oxidation-reduction process
BS21228_12495	COG2088	sporulation resulting in formation of a cellular spore
BS21228_12500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BS21228_12505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BS21228_12510	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BS21228_12515	COG0193	aminoacyl-tRNA hydrolase activity
BS21228_12525	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BS21228_12530	COG2002	toxin-antitoxin pair type II binding
BS21228_12535	COG2244	polysaccharide biosynthetic process
BS21228_12540	COG3956	TIGRFAM MazG family protein
BS21228_12545	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BS21228_12560	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BS21228_12565	COG1098	S1 RNA binding domain
BS21228_12580	COG2208	phosphoserine phosphatase activity
BS21228_12585	COG2304	oxidoreductase activity
BS21228_12590	COG0515	serine threonine protein kinase
BS21228_12595	COG0037	tRNA processing
BS21228_12605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS21228_12610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BS21228_12615	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BS21228_12620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS21228_12625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS21228_12630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BS21228_12635	COG0512	Glutamine amidotransferase of anthranilate synthase
BS21228_12640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS21228_12645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BS21228_12650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BS21228_12655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BS21228_12660	COG1396	sequence-specific DNA binding
BS21228_12665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS21228_12670	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BS21228_12750	COG4463	regulation of RNA biosynthetic process
BS21228_12755	COG3880	PFAM UvrB UvrC protein
BS21228_12760	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BS21228_12765	COG0542	response to heat
BS21228_12770	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BS21228_12775	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BS21228_12780	COG4956	integral membrane protein (PIN domain superfamily)
BS21228_12785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BS21228_12790	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BS21228_12795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BS21228_12805	COG1045	serine acetyltransferase
BS21228_12810	COG0215	cysteine-tRNA ligase activity
BS21228_12815	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BS21228_12820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS21228_12825	COG3688	RNA-binding protein containing a PIN domain
BS21228_12830	COG1595	DNA-templated transcription, initiation
BS21228_12835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BS21228_12840	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS21228_12845	COG0250	Participates in transcription elongation, termination and antitermination
BS21228_12850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BS21228_12855	COG0081	regulation of translation
BS21228_12860	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BS21228_12865	COG0222	ribosome binding
BS21228_12870	COG2813	Specifically methylates the guanine in position
BS21228_12875	COG0085	RNA polymerase activity
BS21228_12880	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BS21228_12885	COG1358	cellular component organization or biogenesis
BS21228_12890	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BS21228_12895	COG0049	tRNA binding
BS21228_12900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BS21228_12905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BS21228_12910	COG0596	Alpha beta hydrolase
BS21228_12915	COG0051	transcription antitermination factor activity, RNA binding
BS21228_12920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BS21228_12925	COG0088	Forms part of the polypeptide exit tunnel
BS21228_12930	COG0089	rRNA binding
BS21228_12935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BS21228_12940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BS21228_12945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BS21228_12950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BS21228_12955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BS21228_12960	COG0255	Belongs to the universal ribosomal protein uL29 family
BS21228_12965	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BS21228_12970	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BS21228_12980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BS21228_12990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BS21228_12995	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BS21228_13000	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BS21228_13005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BS21228_13010	COG1841	ribosomal large subunit assembly
BS21228_13015	COG0200	Binds to the 23S rRNA
BS21228_13020	COG0201	protein transport
BS21228_13025	COG0563	adenylate kinase activity
BS21228_13030	COG0024	Methionine aminopeptidase
BS21228_13035	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BS21228_13040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BS21228_13045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BS21228_13050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BS21228_13055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BS21228_13060	COG0202	RNA polymerase activity
BS21228_13065	COG0203	ribosomal protein L17
BS21228_13070	COG1122	ATPase activity
BS21228_13075	COG1122	ATPase activity
BS21228_13080	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BS21228_13085	COG0101	tRNA pseudouridine synthase activity
BS21228_13090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BS21228_13095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BS21228_13105	COG2226	methyltransferase
BS21228_13115	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_13120	COG0489	protein tyrosine kinase activity
BS21228_13130	COG2194	sulfuric ester hydrolase activity
BS21228_13135	COG0726	polysaccharide deacetylase
BS21228_13215	COG0659	secondary active sulfate transmembrane transporter activity
BS21228_13220	COG0385	Bile acid
BS21228_13225	COG2819	hydrolase of the alpha beta superfamily
BS21228_13230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_13235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_13240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_13245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_13245	COG2207	Transcriptional regulator
BS21228_13250	COG3876	Protein conserved in bacteria
BS21228_13255	COG1472	Belongs to the glycosyl hydrolase 3 family
BS21228_13260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS21228_13265	COG1263	PTS System
BS21228_13265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_13270	COG1737	Transcriptional regulator
BS21228_13275	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BS21228_13280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_13285	COG1683	Conserved Protein
BS21228_13315	COG1595	DNA-templated transcription, initiation
BS21228_13320	COG5662	AntiSigma factor
BS21228_13325	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BS21228_13330	COG4856	YbbR-like protein
BS21228_13335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS21228_13345	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BS21228_13355	COG2169	Transcriptional regulator
BS21228_13360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS21228_13365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS21228_13370	COG3002	Belongs to the UPF0753 family
BS21228_13375	COG0288	reversible hydration of carbon dioxide
BS21228_13385	COG5609	conserved protein (DUF2294)
BS21228_13395	COG0642	Histidine kinase
BS21228_13405	COG0515	serine threonine protein kinase
BS21228_13420	COG1113	amino acid transport
BS21228_13435	COG2602	Beta-lactamase
BS21228_13440	COG2124	cytochrome p450
BS21228_13450	COG0531	amino acid
BS21228_13455	COG0584	glycerophosphoryl diester phosphodiesterase
BS21228_13460	COG2271	Major facilitator Superfamily
BS21228_13475	COG1846	Transcriptional regulator
BS21228_13475	COG0456	acetyltransferase
BS21228_13495	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_13500	COG0697	spore germination
BS21228_13505	COG1917	Cupin 2, conserved barrel domain protein
BS21228_13505	COG2207	Transcriptional regulator
BS21228_13530	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BS21228_13535	COG3591	Belongs to the peptidase S1B family
BS21228_13545	COG0596	Alpha beta hydrolase
BS21228_13550	COG1183	phosphatidylcholine synthase activity
BS21228_13555	COG0586	Pfam SNARE associated Golgi protein
BS21228_13560	COG0688	phosphatidylethanolamine metabolic process
BS21228_13570	COG2312	Erythromycin esterase
BS21228_13575	COG2207	Transcriptional regulator
BS21228_13585	COG1301	dicarboxylic acid transport
BS21228_13590	COG1263	PTS System
BS21228_13590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_13590	COG2190	(PTS) system
BS21228_13595	COG0363	glucosamine-6-phosphate deaminase activity
BS21228_13610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS21228_13615	COG0833	amino acid
BS21228_13620	COG2040	homocysteine
BS21228_13635	COG2066	Belongs to the glutaminase family
BS21228_13640	COG4191	Histidine kinase
BS21228_13645	COG0784	Response regulator, receiver
BS21228_13655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS21228_13660	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_13665	COG2271	Major facilitator Superfamily
BS21228_13670	COG4948	Mandelate Racemase Muconate Lactonizing
BS21228_13675	COG2186	Transcriptional regulator
BS21228_13680	COG2721	sulfolactate sulfo-lyase activity
BS21228_13685	COG3173	Aminoglycoside phosphotransferase
BS21228_13695	COG0697	spore germination
BS21228_13700	COG0745	RESPONSE REGULATOR receiver
BS21228_13705	COG2205	protein histidine kinase activity
BS21228_13710	COG1131	(ABC) transporter
BS21228_13725	COG3773	Cell wall hydrolase
BS21228_13730	COG2304	oxidoreductase activity
BS21228_13740	COG3540	Alkaline phosphatase
BS21228_13745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS21228_13750	COG0805	protein transport
BS21228_13755	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BS21228_13760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BS21228_13765	COG0477	Major facilitator Superfamily
BS21228_13770	COG1309	transcriptional regulator
BS21228_13775	COG0252	asparaginase activity
BS21228_13780	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BS21228_13785	COG1714	RDD family
BS21228_13790	COG3012	SEC-C Motif Domain Protein
BS21228_13790	COG1405	negative regulation of cell septum assembly
BS21228_13800	COG3279	Response regulator of the LytR AlgR family
BS21228_13810	COG1668	transmembrane transport
BS21228_13815	COG0667	Aldo Keto reductase
BS21228_13825	COG1595	DNA-templated transcription, initiation
BS21228_13835	COG1595	DNA-templated transcription, initiation
BS21228_13840	COG1876	peptidase activity
BS21228_13850	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_13855	COG0366	Alpha amylase catalytic
BS21228_13860	COG0803	Belongs to the bacterial solute-binding protein 9 family
BS21228_13865	COG1121	(ABC) transporter
BS21228_13870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS21228_13880	COG2310	stress, protein
BS21228_13885	COG2310	stress, protein
BS21228_13890	COG2310	stress, protein
BS21228_13895	COG0861	Integral membrane protein TerC family
BS21228_13905	COG3853	Toxic anion resistance protein (TelA)
BS21228_13915	COG0477	Major facilitator Superfamily
BS21228_13920	COG2814	Major facilitator Superfamily
BS21228_13925	COG0640	Transcriptional regulator
BS21228_13930	COG4175	Glycine betaine
BS21228_13930	COG0517	IMP dehydrogenase activity
BS21228_13935	COG4176	ABC-type proline glycine betaine transport system permease component
BS21228_13940	COG2113	Glycine betaine
BS21228_13945	COG1473	amidohydrolase
BS21228_13950	COG1288	antiporter activity
BS21228_13965	COG0039	L-malate dehydrogenase activity
BS21228_13980	COG3403	YqcI/YcgG family
BS21228_13995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BS21228_14000	COG1660	Displays ATPase and GTPase activities
BS21228_14010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BS21228_14025	COG2226	methyltransferase
BS21228_14030	COG0583	DNA-binding transcription factor activity
BS21228_14035	COG3458	cephalosporin-C deacetylase activity
BS21228_14040	COG3541	Predicted nucleotidyltransferase
BS21228_14045	COG0506	proline dehydrogenase activity
BS21228_14050	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_14055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS21228_14060	COG2508	Transcriptional regulator
BS21228_14065	COG3689	TIGRFAM TIGR03943 family protein
BS21228_14070	COG0701	Predicted permease
BS21228_14075	COG2267	carboxylic ester hydrolase activity
BS21228_14080	COG0492	ferredoxin-NADP+ reductase activity
BS21228_14085	COG1587	Uroporphyrinogen-III synthase
BS21228_14085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BS21228_14090	COG2146	nitrite reductase [NAD(P)H] activity
BS21228_14095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS21228_14100	COG0243	molybdopterin cofactor binding
BS21228_14105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS21228_14110	COG2223	nitrite transmembrane transporter activity
BS21228_14120	COG1376	ErfK ybiS ycfS ynhG family protein
BS21228_14135	COG0765	amino acid transport
BS21228_14140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS21228_14150	COG1714	RDD family
BS21228_14160	COG1846	Transcriptional regulator
BS21228_14175	COG2723	6-phospho-beta-galactosidase activity
BS21228_14185	COG3209	COG3209 Rhs family protein
BS21228_14195	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BS21228_14200	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BS21228_14205	COG1733	regulation of RNA biosynthetic process
BS21228_14210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_14215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_14220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_14225	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BS21228_14230	COG2814	Major facilitator Superfamily
BS21228_14240	COG0697	spore germination
BS21228_14245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_14255	COG2364	Membrane
BS21228_14265	COG1126	abc transporter atp-binding protein
BS21228_14270	COG0765	amino acid transport
BS21228_14275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS21228_14280	COG0583	DNA-binding transcription factor activity
BS21228_14285	COG0163	prenyltransferase activity
BS21228_14290	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BS21228_14305	COG0596	Alpha beta hydrolase
BS21228_14310	COG3104	oligopeptide transport
BS21228_14315	COG5434	Belongs to the glycosyl hydrolase 28 family
BS21228_14325	COG0697	spore germination
BS21228_14335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS21228_14340	COG1136	(ABC) transporter
BS21228_14345	COG0577	efflux transmembrane transporter activity
BS21228_14350	COG0745	RESPONSE REGULATOR receiver
BS21228_14355	COG5002	protein histidine kinase activity
BS21228_14355	COG3850	Histidine kinase
BS21228_14360	COG0457	Tetratricopeptide repeat
BS21228_14380	COG0527	aspartate kinase activity
BS21228_14385	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_14390	COG4605	iron ion homeostasis
BS21228_14395	COG4604	ABC transporter, ATP-binding protein
BS21228_14400	COG4607	ABC-type enterochelin transport system periplasmic component
BS21228_14410	COG2814	Major facilitator Superfamily
BS21228_14415	COG1309	transcriptional regulator
BS21228_14420	COG0778	Nitroreductase
BS21228_14425	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BS21228_14430	COG0640	Transcriptional regulator
BS21228_14435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_14440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BS21228_14445	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_14450	COG4975	Glucose uptake
BS21228_14455	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_14460	COG4549	nuclear export factor GLE1
BS21228_14465	COG2372	response to copper ion
BS21228_14465	COG1276	copper resistance
BS21228_14470	COG1349	DNA-binding transcription factor activity
BS21228_14480	COG2213	PTS system mannitol-specific
BS21228_14485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_14490	COG0246	Mannitol dehydrogenase
BS21228_14495	COG0473	3-isopropylmalate dehydrogenase activity
BS21228_14500	COG0681	Belongs to the peptidase S26 family
BS21228_14510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BS21228_14520	COG0561	phosphatase activity
BS21228_14525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BS21228_14530	COG1914	H( )-stimulated, divalent metal cation uptake system
BS21228_14535	COG4336	lyase activity
BS21228_14540	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BS21228_14545	COG1984	allophanate hydrolase subunit 2
BS21228_14550	COG1414	Transcriptional regulator
BS21228_14555	COG2755	lipolytic protein G-D-S-L family
BS21228_14565	COG2329	Antibiotic biosynthesis monooxygenase
BS21228_14570	COG0768	penicillin binding
BS21228_14575	COG4989	oxidoreductase activity
BS21228_14580	COG3711	transcriptional antiterminator
BS21228_14585	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_14590	COG2226	methyltransferase
BS21228_14595	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_14600	COG1917	Cupin 2, conserved barrel domain protein
BS21228_14605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_14610	COG3871	stress protein (general stress protein 26)
BS21228_14620	COG2814	Major facilitator Superfamily
BS21228_14625	COG1522	sequence-specific DNA binding
BS21228_14630	COG0551	DNA topoisomerase type I activity
BS21228_14630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS21228_14635	COG0494	nUDIX hydrolase
BS21228_14640	COG0028	Belongs to the TPP enzyme family
BS21228_14670	COG1914	H( )-stimulated, divalent metal cation uptake system
BS21228_14675	COG2261	transglycosylase associated protein
BS21228_14680	COG4876	unkown
BS21228_14685	COG2217	Heavy metal translocating P-type atpase
BS21228_14690	COG3729	General stress protein
BS21228_14695	COG0662	Cupin 2, conserved barrel domain protein
BS21228_14700	COG2329	Antibiotic biosynthesis monooxygenase
BS21228_14705	COG3546	catalase activity
BS21228_14710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BS21228_14715	COG3290	protein histidine kinase activity
BS21228_14720	COG4565	transcriptional regulatory protein
BS21228_14725	COG1301	dicarboxylic acid transport
BS21228_14730	COG0628	permease
BS21228_14735	COG1131	(ABC) transporter
BS21228_14740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS21228_14750	COG1960	acyl-CoA dehydrogenase activity
BS21228_14765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS21228_14770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_14775	COG1181	Belongs to the D-alanine--D-alanine ligase family
BS21228_14780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BS21228_14790	COG0513	Belongs to the DEAD box helicase family
BS21228_14795	COG3402	PFAM membrane-flanked domain
BS21228_14800	COG3428	Bacterial PH domain
BS21228_14805	COG0705	Rhomboid family
BS21228_14810	COG0736	holo-[acyl-carrier-protein] synthase activity
BS21228_14815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BS21228_14820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BS21228_14825	COG0864	Transcriptional regulator
BS21228_14830	COG2337	Toxic component of a toxin-antitoxin (TA) module
BS21228_14835	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_14840	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_14845	COG2172	sigma factor antagonist activity
BS21228_14850	COG2208	phosphoserine phosphatase activity
BS21228_14855	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_14860	COG2172	sigma factor antagonist activity
BS21228_14865	COG1191	sigma factor activity
BS21228_14870	COG2208	phosphoserine phosphatase activity
BS21228_14885	COG1673	EVE domain
BS21228_14890	COG1846	Transcriptional regulator
BS21228_14895	COG2183	response to ionizing radiation
BS21228_14900	COG3091	SprT-like family
BS21228_14940	COG0582	viral genome integration into host DNA
BS21228_14945	COG2856	Zn peptidase
BS21228_14950	COG1396	sequence-specific DNA binding
BS21228_14975	COG1674	ftsk spoiiie
BS21228_14980	COG2946	Replication initiation factor
BS21228_15020	COG0433	COG0433 Predicted ATPase
BS21228_15030	COG5644	endopeptidase inhibitor activity
BS21228_15040	COG0791	NLP P60 protein
BS21228_15040	COG0741	lytic transglycosylase activity
BS21228_15055	COG0457	Tetratricopeptide repeat
BS21228_15085	COG0583	DNA-binding transcription factor activity
BS21228_15090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_15100	COG5444	nuclease activity
BS21228_15105	COG1476	TRANSCRIPTIONal
BS21228_15130	COG0693	protein deglycase activity
BS21228_15135	COG1278	Cold shock
BS21228_15140	COG1329	Transcriptional regulator
BS21228_15150	COG0697	spore germination
BS21228_15155	COG1917	Cupin 2, conserved barrel domain protein
BS21228_15155	COG2207	Transcriptional regulator
BS21228_15165	COG2207	Transcriptional regulator
BS21228_15165	COG3708	Transcriptional regulator
BS21228_15170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_15185	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BS21228_15200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_15205	COG1309	transcriptional regulator
BS21228_15210	COG0697	spore germination
BS21228_15215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_15220	COG2030	dehydratase
BS21228_15225	COG3545	Serine hydrolase
BS21228_15235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_15240	COG0640	Transcriptional regulator
BS21228_15245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS21228_15255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_15260	COG0697	spore germination
BS21228_15265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_15270	COG0076	glutamate decarboxylase activity
BS21228_15275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS21228_15280	COG0640	Transcriptional regulator
BS21228_15285	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS21228_15300	COG4585	Histidine kinase
BS21228_15305	COG2197	response regulator
BS21228_15310	COG2409	Drug exporters of the RND superfamily
BS21228_15315	COG0596	Alpha beta hydrolase
BS21228_15320	COG1811	Na channel or pump
BS21228_15325	COG4978	Transcriptional regulator
BS21228_15325	COG0789	Transcriptional regulator
BS21228_15330	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS21228_15335	COG0778	Nitroreductase
BS21228_15340	COG0346	lactoylglutathione lyase activity
BS21228_15345	COG2259	Doxx family
BS21228_15350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_15375	COG2323	membrane
BS21228_15380	COG0071	Belongs to the small heat shock protein (HSP20) family
BS21228_15395	COG1309	transcriptional regulator
BS21228_15405	COG0456	acetyltransferase
BS21228_15415	COG1113	amino acid transport
BS21228_15420	COG2318	DinB family
BS21228_15425	COG1846	Transcriptional regulator
BS21228_15430	COG1033	growth of symbiont in host cell
BS21228_15430	COG2409	Drug exporters of the RND superfamily
BS21228_15435	COG0778	Nitroreductase
BS21228_15440	COG1846	Transcriptional regulator
BS21228_15445	COG2814	Major facilitator Superfamily
BS21228_15450	COG0730	response to heat
BS21228_15455	COG1802	Transcriptional regulator
BS21228_15460	COG3858	chitin binding
BS21228_15460	COG1388	LysM domain
BS21228_15465	COG1819	glycosyl
BS21228_15485	COG1785	Belongs to the alkaline phosphatase family
BS21228_15490	COG5646	InterPro IPR014922
BS21228_15500	COG0454	-acetyltransferase
BS21228_15505	COG1078	dGTPase activity
BS21228_15510	COG1388	LysM domain
BS21228_15515	COG2814	Major facilitator Superfamily
BS21228_15520	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS21228_15535	COG2723	6-phospho-beta-galactosidase activity
BS21228_15540	COG2188	Transcriptional regulator
BS21228_15545	COG1940	carbohydrate kinase activity
BS21228_15555	COG4124	Belongs to the glycosyl hydrolase 26 family
BS21228_15600	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BS21228_15605	COG0802	atpase or kinase
BS21228_15610	COG1214	PFAM Peptidase M22, glycoprotease
BS21228_15615	COG0456	acetyltransferase
BS21228_15620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BS21228_15625	COG0488	(ABC) transporter
BS21228_15630	COG0315	cyclic pyranopterin monophosphate synthase activity
BS21228_15635	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BS21228_15640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS21228_15645	COG0805	protein transport
BS21228_15660	COG1266	CAAX protease self-immunity
BS21228_15665	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BS21228_15670	COG0459	protein refolding
BS21228_15685	COG0457	Tetratricopeptide repeat
BS21228_15690	COG1063	alcohol dehydrogenase
BS21228_15695	COG2211	Major facilitator Superfamily
BS21228_15700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS21228_15710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS21228_15715	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BS21228_15720	COG4260	virion core protein, lumpy skin disease virus
BS21228_15730	COG2814	Major facilitator Superfamily
BS21228_15735	COG1063	alcohol dehydrogenase
BS21228_15740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BS21228_15745	COG0823	Involved in the tonB-independent uptake of proteins
BS21228_15765	COG2267	carboxylic ester hydrolase activity
BS21228_15775	COG2132	Multicopper oxidase
BS21228_15780	COG1113	amino acid transport
BS21228_15790	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS21228_15795	COG0714	Associated with various cellular activities
BS21228_15800	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BS21228_15805	COG1305	Transglutaminase-like
BS21228_15810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BS21228_15810	COG0519	Catalyzes the synthesis of GMP from XMP
BS21228_15820	COG2252	PERMEase
BS21228_15825	COG3064	Membrane
BS21228_15835	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BS21228_15845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BS21228_15850	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BS21228_15855	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BS21228_15860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BS21228_15865	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BS21228_15870	COG0047	phosphoribosylformylglycinamidine synthase activity
BS21228_15875	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BS21228_15880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BS21228_15885	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BS21228_15890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BS21228_15895	COG0138	bifunctional purine biosynthesis protein purh
BS21228_15900	COG0151	Belongs to the GarS family
BS21228_15905	COG1522	sequence-specific DNA binding
BS21228_15910	COG0531	amino acid
BS21228_15920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BS21228_15925	COG1470	cell adhesion involved in biofilm formation
BS21228_15930	COG4496	protein, YerC YecD
BS21228_15935	COG0069	glutamate synthase activity
BS21228_15940	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BS21228_15945	COG0210	DNA helicase
BS21228_15950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BS21228_15955	COG4851	CamS sex pheromone cAM373 precursor
BS21228_15965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS21228_15970	COG1285	pathogenesis
BS21228_15975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS21228_15980	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS21228_15985	COG0154	amidase activity
BS21228_15990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS21228_16000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BS21228_16005	COG1597	lipid kinase activity
BS21228_16010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BS21228_16015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BS21228_16040	COG5444	nuclease activity
BS21228_16050	COG0457	Tetratricopeptide repeat
BS21228_16060	COG0217	transcriptional regulatory protein
BS21228_16070	COG1309	transcriptional regulator
BS21228_16085	COG3546	catalase activity
BS21228_16090	COG0454	-acetyltransferase
BS21228_16100	COG5578	integral membrane protein
BS21228_16105	COG2972	Histidine kinase
BS21228_16115	COG1653	transport
BS21228_16120	COG1175	transmembrane transport
BS21228_16125	COG0395	ABC-type sugar transport system, permease component
BS21228_16130	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS21228_16135	COG2207	Transcriptional regulator
BS21228_16140	COG2755	lipolytic protein G-D-S-L family
BS21228_16150	COG5578	integral membrane protein
BS21228_16155	COG3401	FG-GAP repeat protein
BS21228_16160	COG3401	FG-GAP repeat protein
BS21228_16165	COG2755	lipolytic protein G-D-S-L family
BS21228_16180	COG1653	transport
BS21228_16185	COG4209	transmembrane transport
BS21228_16190	COG0395	ABC-type sugar transport system, permease component
BS21228_16195	COG1486	melibiose metabolic process
BS21228_16200	COG2323	membrane
BS21228_16205	COG2329	Antibiotic biosynthesis monooxygenase
BS21228_16210	COG0346	lactoylglutathione lyase activity
BS21228_16225	COG5583	Uncharacterized small protein (DUF2292)
BS21228_16230	COG0670	Belongs to the BI1 family
BS21228_16235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS21228_16245	COG3328	transposase activity
BS21228_16255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BS21228_16255	COG2124	cytochrome p450
BS21228_16265	COG1368	sulfuric ester hydrolase activity
BS21228_16270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BS21228_16275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS21228_16280	COG1442	glycosyl transferase family 8
BS21228_16285	COG1216	Glycosyl transferase, family 2
BS21228_16290	COG1442	glycosyl transferase family 8
BS21228_16295	COG2223	nitrite transmembrane transporter activity
BS21228_16300	COG1011	Hydrolase
BS21228_16305	COG0531	amino acid
BS21228_16310	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_16315	COG0840	transmembrane signaling receptor activity
BS21228_16320	COG0488	(ABC) transporter
BS21228_16330	COG0789	Transcriptional regulator
BS21228_16335	COG2814	Major facilitator Superfamily
BS21228_16350	COG0488	(ABC) transporter
BS21228_16355	COG0513	Belongs to the DEAD box helicase family
BS21228_16365	COG3866	Pectate lyase
BS21228_16370	COG0471	metal ion transport
BS21228_16375	COG3290	protein histidine kinase activity
BS21228_16380	COG4565	transcriptional regulatory protein
BS21228_16385	COG3181	Tripartite tricarboxylate transporter family receptor
BS21228_16390	COG2851	Citrate transporter
BS21228_16395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_16400	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BS21228_16405	COG1254	Belongs to the acylphosphatase family
BS21228_16410	COG2258	MOSC domain
BS21228_16430	COG0024	Methionine aminopeptidase
BS21228_16435	COG1263	PTS System
BS21228_16435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_16440	COG1368	sulfuric ester hydrolase activity
BS21228_16455	COG1115	amino acid carrier protein
BS21228_16465	COG0697	spore germination
BS21228_16470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_16470	COG1263	PTS System
BS21228_16475	COG0366	Alpha amylase catalytic
BS21228_16480	COG2188	Transcriptional regulator
BS21228_16485	COG0778	Nitroreductase
BS21228_16490	COG0737	Belongs to the 5'-nucleotidase family
BS21228_16495	COG0693	protein deglycase activity
BS21228_16505	COG2814	Major facilitator Superfamily
BS21228_16510	COG4840	Belongs to the UPF0435 family
BS21228_16515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS21228_16520	COG4980	gas vesicle protein
BS21228_16525	COG1295	ribonuclease BN
BS21228_16530	COG0477	Major facilitator Superfamily
BS21228_16535	COG0387	Pfam Sodium calcium exchanger
BS21228_16545	COG0668	transmembrane transport
BS21228_16550	COG0535	radical SAM domain protein
BS21228_16560	COG0726	polysaccharide deacetylase
BS21228_16565	COG2084	Dehydrogenase
BS21228_16570	COG0598	Magnesium transport protein CorA
BS21228_16575	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BS21228_16580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BS21228_16590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS21228_16595	COG4637	Psort location Cytoplasmic, score
BS21228_16605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS21228_16610	COG0022	dehydrogenase e1 component
BS21228_16615	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS21228_16620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS21228_16625	COG3284	Transcriptional regulator
BS21228_16635	COG1742	UPF0060 membrane protein
BS21228_16660	COG4842	Belongs to the WXG100 family
BS21228_16665	COG1486	melibiose metabolic process
BS21228_16670	COG1737	Transcriptional regulator
BS21228_16675	COG1263	PTS System
BS21228_16675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_16680	COG5434	Belongs to the glycosyl hydrolase 28 family
BS21228_16685	COG1132	(ABC) transporter
BS21228_16690	COG1132	(ABC) transporter
BS21228_16695	COG2259	Doxx family
BS21228_16700	COG2514	catechol 2,3-dioxygenase activity
BS21228_16705	COG4977	sequence-specific DNA binding
BS21228_16705	COG1917	Cupin 2, conserved barrel domain protein
BS21228_16710	COG2814	Major facilitator Superfamily
BS21228_16715	COG1082	Xylose isomerase domain protein TIM barrel
BS21228_16725	COG4585	Histidine kinase
BS21228_16730	COG2197	response regulator
BS21228_16735	COG1131	(ABC) transporter
BS21228_16740	COG1511	domain protein
BS21228_16740	COG0842	Transport permease protein
BS21228_16745	COG0842	Transport permease protein
BS21228_16750	COG1695	Transcriptional regulator
BS21228_16755	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BS21228_16760	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BS21228_16765	COG1309	transcriptional regulator
BS21228_16770	COG2814	Major facilitator Superfamily
BS21228_16775	COG2318	DinB family
BS21228_16785	COG1846	Transcriptional regulator
BS21228_16790	COG0392	lysyltransferase activity
BS21228_16790	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BS21228_16795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_16800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_16805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_16810	COG0384	phenazine biosynthesis protein PhzF
BS21228_16815	COG0778	Nitroreductase
BS21228_16830	COG1090	epimerase
BS21228_16835	COG2137	regulation of response to DNA damage stimulus
BS21228_16845	COG2814	Major facilitator Superfamily
BS21228_16860	COG3103	Sh3 type 3 domain protein
BS21228_16865	COG5658	integral membrane protein
BS21228_16870	COG0596	Alpha beta hydrolase
BS21228_16875	COG0463	Glycosyl transferase, family 2
BS21228_16880	COG4485	Bacterial membrane protein, YfhO
BS21228_16885	COG1988	membrane-bound metal-dependent
BS21228_16890	COG1194	a g-specific adenine glycosylase
BS21228_16900	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_16915	COG3557	Belongs to the UPF0374 family
BS21228_16920	COG1132	(ABC) transporter
BS21228_16925	COG4129	membrane
BS21228_16930	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS21228_16935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BS21228_16940	COG0735	belongs to the Fur family
BS21228_17050	COG4326	sporulation control protein
BS21228_17060	COG5577	PFAM Coat F domain
BS21228_17065	COG3340	Belongs to the peptidase S51 family
BS21228_17070	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BS21228_17085	COG0753	catalase activity
BS21228_17090	COG1116	anion transmembrane transporter activity
BS21228_17095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS21228_17100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS21228_17105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS21228_17115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BS21228_17125	COG1476	TRANSCRIPTIONal
BS21228_17135	COG3382	B3 4 domain protein
BS21228_17140	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BS21228_17150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BS21228_17155	COG0789	Transcriptional regulator
BS21228_17160	COG1664	Polymer-forming cytoskeletal
BS21228_17165	COG1664	Polymer-forming cytoskeletal
BS21228_17170	COG2766	serine protein kinase
BS21228_17175	COG2718	Belongs to the UPF0229 family
BS21228_17180	COG1846	Transcriptional regulator
BS21228_17185	COG1566	PFAM secretion protein HlyD family protein
BS21228_17190	COG2814	Major facilitator Superfamily
BS21228_17195	COG0655	NAD(P)H dehydrogenase (quinone) activity
BS21228_17215	COG1725	Transcriptional regulator
BS21228_17220	COG1131	(ABC) transporter
BS21228_17225	COG1131	(ABC) transporter
BS21228_17230	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS21228_17235	COG1278	Cold shock
BS21228_17245	COG1464	Belongs to the NlpA lipoprotein family
BS21228_17250	COG3706	GGDEF domain
BS21228_17255	COG1823	symporter activity
BS21228_17260	COG5444	nuclease activity
BS21228_17285	COG0582	viral genome integration into host DNA
BS21228_17290	COG2946	Replication initiation factor
BS21228_17340	COG5644	endopeptidase inhibitor activity
BS21228_17345	COG0741	lytic transglycosylase activity
BS21228_17345	COG0791	NLP P60 protein
BS21228_17365	COG0457	Tetratricopeptide repeat
BS21228_17395	COG1525	nuclease
BS21228_17395	COG0737	Belongs to the 5'-nucleotidase family
BS21228_17395	COG4085	toxin activity
BS21228_17400	COG3764	Sortase (surface protein transpeptidase)
BS21228_17405	COG0564	pseudouridine synthase activity
BS21228_17415	COG0517	IMP dehydrogenase activity
BS21228_17420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS21228_17425	COG3153	acetyltransferase
BS21228_17425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS21228_17430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS21228_17435	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BS21228_17440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BS21228_17445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BS21228_17450	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BS21228_17455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS21228_17460	COG4585	Histidine kinase
BS21228_17460	COG2203	Gaf domain
BS21228_17465	COG2197	response regulator
BS21228_17470	COG0431	NADPH-dependent FMN reductase
BS21228_17485	COG1388	LysM domain
BS21228_17485	COG0791	NLP P60 protein
BS21228_17490	COG1959	2 iron, 2 sulfur cluster binding
BS21228_17495	COG0668	transmembrane transport
BS21228_17500	COG2719	SpoVR family
BS21228_17505	COG1785	Belongs to the alkaline phosphatase family
BS21228_17510	COG1388	LysM domain
BS21228_17510	COG0791	NLP P60 protein
BS21228_17515	COG0583	DNA-binding transcription factor activity
BS21228_17520	COG0372	Belongs to the citrate synthase family
BS21228_17525	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_17530	COG0531	amino acid
BS21228_17535	COG0733	neurotransmitter:sodium symporter activity
BS21228_17540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_17545	COG0456	acetyltransferase
BS21228_17560	COG1595	DNA-templated transcription, initiation
BS21228_17565	COG0667	Aldo Keto reductase
BS21228_17570	COG0204	Acyl-transferase
BS21228_17575	COG1253	flavin adenine dinucleotide binding
BS21228_17580	COG0789	Transcriptional regulator
BS21228_17590	COG1253	flavin adenine dinucleotide binding
BS21228_17595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS21228_17600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS21228_17605	COG0584	glycerophosphoryl diester phosphodiesterase
BS21228_17615	COG0668	transmembrane transport
BS21228_17620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BS21228_17625	COG0726	polysaccharide deacetylase
BS21228_17630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS21228_17635	COG1757	Na H antiporter
BS21228_17640	COG0589	response to stress
BS21228_17650	COG1132	(ABC) transporter
BS21228_17655	COG1132	(ABC) transporter
BS21228_17660	COG0702	epimerase
BS21228_17685	COG0189	ligase activity
BS21228_17690	COG0189	ligase activity
BS21228_17695	COG4399	Belongs to the UPF0754 family
BS21228_17700	COG3679	Belongs to the UPF0342 family
BS21228_17710	COG0561	phosphatase activity
BS21228_17715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS21228_17720	COG0475	glutathione-regulated potassium exporter activity
BS21228_17725	COG0490	domain, Protein
BS21228_17735	COG1024	Enoyl-CoA hydratase
BS21228_17745	COG4152	abc transporter atp-binding protein
BS21228_17750	COG1668	transmembrane transport
BS21228_17755	COG0420	3'-5' exonuclease activity
BS21228_17760	COG4717	serine-type aminopeptidase activity
BS21228_17765	COG3481	metal-dependent phosphohydrolase, HD sub domain
BS21228_17775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS21228_17805	COG1846	Transcriptional regulator
BS21228_17810	COG4980	gas vesicle protein
BS21228_17825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BS21228_17830	COG0537	adenosine 5'-monophosphoramidase activity
BS21228_17835	COG1131	(ABC) transporter
BS21228_17840	COG4473	ABC transporter
BS21228_17850	COG1473	amidohydrolase
BS21228_17855	COG3069	C4-dicarboxylate transmembrane transporter activity
BS21228_17865	COG2329	Antibiotic biosynthesis monooxygenase
BS21228_17870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS21228_17875	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BS21228_17890	COG1309	transcriptional regulator
BS21228_17895	COG1511	domain protein
BS21228_17900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS21228_17905	COG4377	Putative membrane peptidase family (DUF2324)
BS21228_17915	COG1363	Peptidase, m42
BS21228_17920	COG4405	Protein conserved in bacteria
BS21228_17925	COG1301	dicarboxylic acid transport
BS21228_17935	COG1234	tRNA 3'-trailer cleavage
BS21228_17940	COG0095	Lipoate-protein ligase
BS21228_17945	COG0702	epimerase
BS21228_17950	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_17960	COG0501	Belongs to the peptidase M48B family
BS21228_17970	COG0456	acetyltransferase
BS21228_17975	COG0604	alcohol dehydrogenase
BS21228_17980	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BS21228_17985	COG0406	alpha-ribazole phosphatase activity
BS21228_17990	COG0183	Belongs to the thiolase family
BS21228_17995	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_18000	COG1268	BioY protein
BS21228_18005	COG0840	transmembrane signaling receptor activity
BS21228_18015	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_18025	COG4903	ComK protein
BS21228_18030	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_18040	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS21228_18055	COG0398	Pfam SNARE associated Golgi protein
BS21228_18060	COG0681	Belongs to the peptidase S26 family
BS21228_18065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS21228_18070	COG1846	Transcriptional regulator
BS21228_18085	COG0738	Major facilitator superfamily
BS21228_18090	COG0673	inositol 2-dehydrogenase activity
BS21228_18095	COG0561	phosphatase activity
BS21228_18100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS21228_18105	COG1609	Transcriptional regulator
BS21228_18110	COG3180	Ammonia monooxygenase
BS21228_18115	COG2814	Major facilitator Superfamily
BS21228_18115	COG0477	Major facilitator Superfamily
BS21228_18120	COG4533	DNA binding
BS21228_18140	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BS21228_18145	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BS21228_18150	COG1074	ATP-dependent DNA helicase activity
BS21228_18155	COG0420	3'-5' exonuclease activity
BS21228_18165	COG1403	HNH endonuclease
BS21228_18205	COG5337	Spore coat protein CotH
BS21228_18210	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS21228_18220	COG1404	Belongs to the peptidase S8 family
BS21228_18230	COG0367	asparagine synthase
BS21228_18235	COG1562	ergosterol biosynthetic process
BS21228_18240	COG0534	Mate efflux family protein
BS21228_18245	COG1917	Cupin 2, conserved barrel domain protein
BS21228_18245	COG2207	Transcriptional regulator
BS21228_18250	COG1609	Transcriptional regulator
BS21228_18255	COG0673	inositol 2-dehydrogenase activity
BS21228_18260	COG2318	DinB family
BS21228_18265	COG1279	arginine transmembrane transporter activity
BS21228_18270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_18275	COG1357	PFAM Pentapeptide repeats (8 copies)
BS21228_18280	COG2267	carboxylic ester hydrolase activity
BS21228_18290	COG2153	protein acetylation
BS21228_18295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BS21228_18295	COG0646	methionine synthase
BS21228_18300	COG1666	GTP binding
BS21228_18305	COG2996	Protein conserved in bacteria
BS21228_18315	COG1307	EDD domain protein, DegV family
BS21228_18320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_18335	COG0561	phosphatase activity
BS21228_18340	COG1073	alpha beta
BS21228_18345	COG2151	metal-sulfur cluster biosynthetic enzyme
BS21228_18365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BS21228_18380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BS21228_18385	COG0505	Belongs to the CarA family
BS21228_18390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BS21228_18395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BS21228_18415	COG2267	carboxylic ester hydrolase activity
BS21228_18425	COG1744	ABC transporter substrate-binding protein PnrA-like
BS21228_18440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS21228_18445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS21228_18450	COG5504	Zn-dependent protease
BS21228_18455	COG0444	Belongs to the ABC transporter superfamily
BS21228_18460	COG4608	Belongs to the ABC transporter superfamily
BS21228_18470	COG0601	transmembrane transport
BS21228_18475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS21228_18485	COG0180	Tryptophanyl-tRNA synthetase
BS21228_18490	COG4166	transmembrane transport
BS21228_18495	COG0601	transmembrane transport
BS21228_18500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS21228_18505	COG0444	Belongs to the ABC transporter superfamily
BS21228_18510	COG4608	Belongs to the ABC transporter superfamily
BS21228_18515	COG2814	Major facilitator Superfamily
BS21228_18520	COG0456	acetyltransferase
BS21228_18525	COG1393	Belongs to the ArsC family
BS21228_18530	COG0861	Integral membrane protein TerC family
BS21228_18535	COG4862	establishment of competence for transformation
BS21228_18540	COG4469	Competence protein
BS21228_18545	COG1164	Oligoendopeptidase f
BS21228_18565	COG2346	COG2346, Truncated hemoglobins
BS21228_18570	COG0741	lytic transglycosylase activity
BS21228_18575	COG4116	CYTH
BS21228_18585	COG2357	RelA SpoT domain protein
BS21228_18590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BS21228_18595	COG0564	pseudouridine synthase activity
BS21228_18600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BS21228_18605	COG0569	domain protein
BS21228_18605	COG0475	glutathione-regulated potassium exporter activity
BS21228_18610	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BS21228_18615	COG0352	thiamine-phosphate diphosphorylase activity
BS21228_18620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS21228_18625	COG2104	thiamine diphosphate biosynthetic process
BS21228_18630	COG2022	thiamine diphosphate biosynthetic process
BS21228_18635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS21228_18640	COG0351	phosphomethylpyrimidine kinase
BS21228_18645	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BS21228_18700	COG0210	DNA helicase
BS21228_18710	COG2153	protein acetylation
BS21228_18715	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BS21228_18720	COG2382	esterase
BS21228_18725	COG0626	cystathionine gamma-synthase activity
BS21228_18730	COG0626	cystathionine gamma-synthase activity
BS21228_18735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_18740	COG5505	Protein of unknown function (DUF819)
BS21228_18775	COG1396	sequence-specific DNA binding
BS21228_18850	COG0457	Tetratricopeptide repeat
BS21228_18855	COG5444	nuclease activity
BS21228_18865	COG3328	transposase activity
BS21228_18925	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BS21228_18935	COG3711	transcriptional antiterminator
BS21228_18935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_18940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS21228_18940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS21228_18940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_18945	COG1482	cell wall glycoprotein biosynthetic process
BS21228_18960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_18970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BS21228_18990	COG0109	protoheme IX farnesyltransferase activity
BS21228_19000	COG0726	polysaccharide deacetylase
BS21228_19015	COG5504	Zn-dependent protease
BS21228_19020	COG2205	protein histidine kinase activity
BS21228_19035	COG2427	Protein of unknown function (DUF1641)
BS21228_19045	COG1051	belongs to the nudix hydrolase family
BS21228_19055	COG2124	cytochrome p450
BS21228_19060	COG1819	glycosyl
BS21228_19070	COG1587	Uroporphyrinogen-III synthase
BS21228_19075	COG0390	transport system, permease component
BS21228_19080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS21228_19085	COG0697	spore germination
BS21228_19100	COG1252	NADH dehydrogenase
BS21228_19105	COG1904	glucuronate isomerase
BS21228_19110	COG2211	Major facilitator Superfamily
BS21228_19115	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BS21228_19120	COG1063	alcohol dehydrogenase
BS21228_19125	COG1312	Catalyzes the dehydration of D-mannonate
BS21228_19130	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_19135	COG2271	Major facilitator Superfamily
BS21228_19140	COG1609	Transcriptional regulator
BS21228_19145	COG0246	Mannitol dehydrogenase
BS21228_19150	COG2721	sulfolactate sulfo-lyase activity
BS21228_19155	COG0730	response to heat
BS21228_19160	COG2318	DinB family
BS21228_19175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS21228_19180	COG0457	Tetratricopeptide repeat
BS21228_19195	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_19195	COG1388	LysM domain
BS21228_19195	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_19205	COG4195	phage-related replication protein
BS21228_19210	COG3546	catalase activity
BS21228_19215	COG2856	Zn peptidase
BS21228_19220	COG1396	sequence-specific DNA binding
BS21228_19230	COG1522	sequence-specific DNA binding
BS21228_19235	COG1484	DNA-dependent DNA replication
BS21228_19255	COG1595	DNA-templated transcription, initiation
BS21228_19260	COG3728	DNA packaging
BS21228_19260	COG5484	DNA packaging
BS21228_19265	COG1783	phage Terminase large subunit
BS21228_19270	COG5518	Phage portal protein
BS21228_19275	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BS21228_19280	COG4653	Phage capsid family
BS21228_19330	COG5412	phage tail tape measure protein
BS21228_19330	COG3953	SLT domain
BS21228_19330	COG5412	phage tail tape measure protein
BS21228_19330	COG3953	SLT domain
BS21228_19330	COG3953	SLT domain
BS21228_19330	COG5412	phage tail tape measure protein
BS21228_19335	COG1652	LysM domain
BS21228_19340	COG4193	domain, Protein
BS21228_19350	COG3628	GPW Gp25 family protein
BS21228_19355	COG3299	homolog of phage Mu protein gp47
BS21228_19360	COG3778	Protein conserved in bacteria
BS21228_19400	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_19400	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_19415	COG0306	phosphate transporter
BS21228_19420	COG1392	Phosphate transport regulator
BS21228_19425	COG0531	amino acid
BS21228_19430	COG0346	lactoylglutathione lyase activity
BS21228_19435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BS21228_19440	COG0463	Glycosyl transferase, family 2
BS21228_19445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS21228_19450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS21228_19455	COG2362	D-Aminopeptidase
BS21228_19460	COG0601	transmembrane transport
BS21228_19465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS21228_19470	COG0444	Belongs to the ABC transporter superfamily
BS21228_19475	COG4166	transmembrane transport
BS21228_19480	COG1619	proteins homologs of microcin C7 resistance protein MccF
BS21228_19485	COG4948	Mandelate Racemase Muconate Lactonizing
BS21228_19490	COG0791	NLP P60 protein
BS21228_19495	COG4608	Belongs to the ABC transporter superfamily
BS21228_19500	COG2706	6-phosphogluconolactonase activity
BS21228_19510	COG1607	acyl-coa hydrolase
BS21228_19515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS21228_19515	COG1017	nitric oxide dioxygenase activity
BS21228_19525	COG2323	membrane
BS21228_19530	COG2318	DinB family
BS21228_19535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_19540	COG2076	Multidrug Resistance protein
BS21228_19545	COG2076	Multidrug Resistance protein
BS21228_19550	COG0788	formyltetrahydrofolate deformylase activity
BS21228_19555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BS21228_19560	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BS21228_19565	COG1764	response to oxidative stress
BS21228_19570	COG1846	Transcriptional regulator
BS21228_19575	COG1764	response to oxidative stress
BS21228_19585	COG0590	tRNA wobble adenosine to inosine editing
BS21228_19590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS21228_19595	COG1404	Belongs to the peptidase S8 family
BS21228_19600	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_19605	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BS21228_19610	COG1122	ATPase activity
BS21228_19615	COG4721	ABC-type cobalt transport system, permease component
BS21228_19625	COG0745	RESPONSE REGULATOR receiver
BS21228_19630	COG3850	Histidine kinase
BS21228_19630	COG5002	protein histidine kinase activity
BS21228_19635	COG3212	peptidase
BS21228_19640	COG3212	peptidase
BS21228_19655	COG2239	Acts as a magnesium transporter
BS21228_19660	COG0789	Transcriptional regulator
BS21228_19675	COG1846	Transcriptional regulator
BS21228_19680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS21228_19685	COG0726	polysaccharide deacetylase
BS21228_19690	COG1408	metallophosphoesterase
BS21228_19700	COG0463	Glycosyl transferase, family 2
BS21228_19705	COG3285	dna ligase
BS21228_19705	COG1793	dna ligase
BS21228_19710	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BS21228_19715	COG5001	Diguanylate cyclase
BS21228_19715	COG3300	MHYT domain
BS21228_19720	COG0586	Pfam SNARE associated Golgi protein
BS21228_19725	COG0861	Integral membrane protein TerC family
BS21228_19730	COG1191	sigma factor activity
BS21228_19750	COG0501	Belongs to the peptidase M48B family
BS21228_19755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS21228_19775	COG3594	Acyltransferase
BS21228_19780	COG5002	protein histidine kinase activity
BS21228_19785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS21228_19790	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BS21228_19795	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BS21228_19800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS21228_19805	COG0436	Aminotransferase
BS21228_19810	COG1850	ribulose-bisphosphate carboxylase activity
BS21228_19815	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BS21228_19820	COG0235	Class ii aldolase
BS21228_19825	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BS21228_19830	COG3339	Conserved Protein
BS21228_19845	COG3852	Histidine kinase
BS21228_19850	COG1846	Transcriptional regulator
BS21228_19855	COG1360	Flagellar Motor Protein
BS21228_19860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BS21228_19865	COG0542	response to heat
BS21228_19870	COG3949	Membrane
BS21228_19875	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BS21228_19880	COG0720	synthase
BS21228_19885	COG0602	queuosine metabolic process
BS21228_19890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BS21228_19900	COG4873	Protein conserved in bacteria
BS21228_19910	COG3773	Cell wall hydrolase
BS21228_19915	COG2244	polysaccharide biosynthetic process
BS21228_19920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_19925	COG2217	Heavy metal translocating P-type atpase
BS21228_19935	COG0006	proline dipeptidase activity
BS21228_19940	COG1609	Transcriptional regulator
BS21228_19945	COG3711	transcriptional antiterminator
BS21228_19950	COG1263	PTS System
BS21228_19950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_19950	COG2190	(PTS) system
BS21228_19955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_19960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BS21228_19970	COG1533	DNA photolyase activity
BS21228_19975	COG0456	acetyltransferase
BS21228_19980	COG0840	transmembrane signaling receptor activity
BS21228_19985	COG2084	Dehydrogenase
BS21228_19990	COG3328	transposase activity
BS21228_19995	COG2340	Cysteine-rich secretory protein family
BS21228_20000	COG0768	penicillin binding
BS21228_20005	COG4191	Histidine kinase
BS21228_20010	COG0436	Aminotransferase
BS21228_20020	COG0835	chemotaxis
BS21228_20020	COG0784	Response regulator, receiver
BS21228_20030	COG2814	Major facilitator Superfamily
BS21228_20035	COG1376	ErfK ybiS ycfS ynhG family protein
BS21228_20040	COG1408	metallophosphoesterase
BS21228_20045	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_20050	COG2200	EAL domain
BS21228_20055	COG4703	Protein of unknown function (DUF1797)
BS21228_20060	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BS21228_20070	COG0517	IMP dehydrogenase activity
BS21228_20075	COG0583	DNA-binding transcription factor activity
BS21228_20080	COG0716	FMN binding
BS21228_20090	COG0716	FMN binding
BS21228_20095	COG2171	N-acyltransferase activity
BS21228_20100	COG1473	amidohydrolase
BS21228_20110	COG0668	transmembrane transport
BS21228_20115	COG0450	alkyl hydroperoxide reductase
BS21228_20120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_20140	COG0746	molybdenum cofactor guanylyltransferase activity
BS21228_20145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS21228_20150	COG0303	'Molybdopterin
BS21228_20155	COG1763	Mo-molybdopterin cofactor biosynthetic process
BS21228_20160	COG0314	molybdopterin synthase activity
BS21228_20165	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BS21228_20175	COG1132	(ABC) transporter
BS21228_20185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS21228_20190	COG1136	(ABC) transporter
BS21228_20195	COG0577	efflux transmembrane transporter activity
BS21228_20200	COG1349	DNA-binding transcription factor activity
BS21228_20205	COG1105	Belongs to the carbohydrate kinase PfkB family
BS21228_20210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS21228_20210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_20210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS21228_20215	COG0681	Belongs to the peptidase S26 family
BS21228_20225	COG0488	(ABC) transporter
BS21228_20230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS21228_20235	COG2309	aminopeptidase activity
BS21228_20245	COG1077	Cell shape determining protein MreB Mrl
BS21228_20250	COG2002	toxin-antitoxin pair type II binding
BS21228_20255	COG3852	Histidine kinase
BS21228_20260	COG2105	PFAM AIG2 family protein
BS21228_20260	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BS21228_20265	COG0569	domain protein
BS21228_20270	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BS21228_20275	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS21228_20285	COG0561	phosphatase activity
BS21228_20290	COG0242	peptide deformylase activity
BS21228_20305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS21228_20310	COG0022	dehydrogenase e1 component
BS21228_20315	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS21228_20320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS21228_20325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_20335	COG1982	Orn Lys Arg decarboxylase major
BS21228_20340	COG4476	Belongs to the UPF0223 family
BS21228_20345	COG4493	Belongs to the UPF0637 family
BS21228_20355	COG0483	inositol monophosphate 1-phosphatase activity
BS21228_20370	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BS21228_20425	COG4896	Protein conserved in bacteria
BS21228_20435	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BS21228_20440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BS21228_20445	COG2066	Belongs to the glutaminase family
BS21228_20450	COG4838	Belongs to the UPF0358 family
BS21228_20455	COG0772	Belongs to the SEDS family
BS21228_20460	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BS21228_20465	COG1612	heme a metabolic process
BS21228_20470	COG0109	protoheme IX farnesyltransferase activity
BS21228_20475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS21228_20475	COG2010	Cytochrome c
BS21228_20480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BS21228_20485	COG1845	cytochrome c oxidase, subunit III
BS21228_20490	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BS21228_20495	COG3336	cytochrome c oxidase
BS21228_20505	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BS21228_20510	COG2340	Cysteine-rich secretory protein family
BS21228_20525	COG3679	Belongs to the UPF0342 family
BS21228_20530	COG4471	UPF0298 protein
BS21228_20535	COG0742	ribosomal rna small subunit methyltransferase
BS21228_20540	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BS21228_20545	COG3314	Sporulation integral membrane protein YlbJ
BS21228_20550	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS21228_20555	COG3480	Lon protease (S16) C-terminal proteolytic domain
BS21228_20560	COG1323	Belongs to the UPF0348 family
BS21228_20570	COG1399	metal-binding, possibly nucleic acid-binding protein
BS21228_20575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BS21228_20585	COG0454	-acetyltransferase
BS21228_20590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS21228_20595	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BS21228_20600	COG2001	Belongs to the MraZ family
BS21228_20605	COG0275	rRNA processing
BS21228_20610	COG4839	cell division protein FtsL
BS21228_20620	COG0768	penicillin binding
BS21228_20625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BS21228_20630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS21228_20635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BS21228_20640	COG0772	Belongs to the SEDS family
BS21228_20645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS21228_20650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BS21228_20655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BS21228_20660	COG3879	Bacterial protein of unknown function (DUF881)
BS21228_20665	COG3879	Bacterial protein of unknown function (DUF881)
BS21228_20670	COG3856	small basic protein
BS21228_20675	COG0849	cell division
BS21228_20680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BS21228_20685	COG4412	M6 family metalloprotease domain protein
BS21228_20685	COG1404	Belongs to the peptidase S8 family
BS21228_20695	COG1191	sigma factor activity
BS21228_20700	COG1191	sigma factor activity
BS21228_20705	COG1119	ATPase activity
BS21228_20710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS21228_20715	COG1873	PFAM PRC-barrel domain
BS21228_20725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BS21228_20730	COG1799	cell septum assembly
BS21228_20735	COG0762	integral membrane protein
BS21228_20740	COG2302	S4 RNA-binding domain
BS21228_20745	COG3599	regulation of cell shape
BS21228_20750	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BS21228_20755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS21228_20760	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BS21228_20765	COG0564	pseudouridine synthase activity
BS21228_20770	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BS21228_20775	COG2233	PERMEase
BS21228_20780	COG0540	Belongs to the ATCase OTCase family
BS21228_20785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BS21228_20790	COG0505	Belongs to the CarA family
BS21228_20795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BS21228_20800	COG0543	2 iron, 2 sulfur cluster binding
BS21228_20805	COG0167	dihydroorotate dehydrogenase activity
BS21228_20810	COG0284	orotidine-5'-phosphate decarboxylase activity
BS21228_20815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BS21228_20820	COG0175	sulfate reduction
BS21228_20825	COG0306	phosphate transporter
BS21228_20830	COG2046	Belongs to the sulfate adenylyltransferase family
BS21228_20835	COG0529	Catalyzes the synthesis of activated sulfate
BS21228_20840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BS21228_20845	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BS21228_20850	COG1648	precorrin-2 dehydrogenase activity
BS21228_20860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BS21228_20865	COG1561	YicC-like family, N-terminal region
BS21228_20870	COG2052	Domain of unknown function (DUF370)
BS21228_20875	COG0194	GDP metabolic process
BS21228_20880	COG1758	RNA polymerase activity
BS21228_20885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS21228_20890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS21228_20895	COG0242	peptide deformylase activity
BS21228_20900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BS21228_20905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BS21228_20905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BS21228_20915	COG0631	protein serine/threonine phosphatase activity
BS21228_20920	COG2815	serine threonine protein kinase
BS21228_20920	COG0515	serine threonine protein kinase
BS21228_20925	COG1162	GTPase activity
BS21228_20930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BS21228_20935	COG1564	THIamine pyrophosphokinase
BS21228_20945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BS21228_20950	COG1302	Protein conserved in bacteria
BS21228_20955	COG1461	Dihydroxyacetone kinase
BS21228_20960	COG1760	l-serine dehydratase
BS21228_20965	COG1760	l-serine dehydratase
BS21228_20970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BS21228_20975	COG2050	protein possibly involved in aromatic compounds catabolism
BS21228_20975	COG1349	DNA-binding transcription factor activity
BS21228_20980	COG0416	fatty acid biosynthetic process
BS21228_20985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BS21228_20990	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_20995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS21228_21000	COG0571	ribonuclease III activity
BS21228_21005	COG1196	nuclear chromosome segregation
BS21228_21010	COG0552	protein localization to endoplasmic reticulum
BS21228_21020	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BS21228_21025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BS21228_21030	COG0228	four-way junction DNA binding
BS21228_21035	COG1837	Belongs to the UPF0109 family
BS21228_21045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BS21228_21050	COG0336	Belongs to the RNA methyltransferase TrmD family
BS21228_21055	COG0335	large ribosomal subunit rRNA binding
BS21228_21060	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BS21228_21065	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BS21228_21075	COG2257	FlhB HrpN YscU SpaS Family
BS21228_21080	COG0045	succinate-CoA ligase (ADP-forming) activity
BS21228_21085	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BS21228_21090	COG0758	DNA mediated transformation
BS21228_21095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS21228_21100	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BS21228_21105	COG4974	Belongs to the 'phage' integrase family
BS21228_21110	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BS21228_21115	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BS21228_21120	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BS21228_21125	COG1815	bacterial-type flagellum-dependent cell motility
BS21228_21130	COG1558	bacterial-type flagellum-dependent cell motility
BS21228_21135	COG1677	Flagellar hook-basal body complex protein FliE
BS21228_21145	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS21228_21150	COG1317	bacterial-type flagellum organization
BS21228_21170	COG2882	bacterial-type flagellum organization
BS21228_21175	COG3334	PFAM MgtE intracellular
BS21228_21180	COG3144	bacterial-type flagellum assembly
BS21228_21185	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BS21228_21190	COG4786	Flagellar basal body rod
BS21228_21195	COG1582	Flagellar protein (FlbD)
BS21228_21200	COG1580	Controls the rotational direction of flagella during chemotaxis
BS21228_21205	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS21228_21210	COG1776	CheC inhibitor of MCP methylation
BS21228_21210	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS21228_21215	COG2201	protein-glutamate methylesterase activity
BS21228_21220	COG3190	flagellar
BS21228_21225	COG1338	Plays a role in the flagellum-specific transport system
BS21228_21230	COG1987	bacterial-type flagellum assembly
BS21228_21240	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS21228_21245	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS21228_21250	COG1419	protein localization to endoplasmic reticulum
BS21228_21255	COG0455	bacterial-type flagellum organization
BS21228_21260	COG2201	protein-glutamate methylesterase activity
BS21228_21265	COG2198	Histidine kinase
BS21228_21265	COG0643	Histidine kinase
BS21228_21270	COG0835	chemotaxis
BS21228_21280	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BS21228_21285	COG1191	sigma factor activity
BS21228_21295	COG0052	Belongs to the universal ribosomal protein uS2 family
BS21228_21300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BS21228_21305	COG0528	UMP kinase activity
BS21228_21310	COG0233	cytoplasmic translational termination
BS21228_21315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BS21228_21320	COG4589	Belongs to the CDS family
BS21228_21325	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BS21228_21330	COG0750	zinc metalloprotease
BS21228_21335	COG0442	prolyl-tRNA aminoacylation
BS21228_21340	COG2176	DNA-directed DNA polymerase activity
BS21228_21345	COG0779	Required for maturation of 30S ribosomal subunits
BS21228_21350	COG0195	Participates in both transcription termination and antitermination
BS21228_21355	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BS21228_21360	COG1358	cellular component organization or biogenesis
BS21228_21365	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BS21228_21370	COG1550	Protein conserved in bacteria
BS21228_21375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BS21228_21380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BS21228_21385	COG0196	riboflavin kinase activity
BS21228_21390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BS21228_21395	COG1185	polyribonucleotide nucleotidyltransferase activity
BS21228_21400	COG0726	polysaccharide deacetylase
BS21228_21405	COG0612	Peptidase, M16
BS21228_21410	COG1873	PFAM PRC-barrel domain
BS21228_21415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS21228_21420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS21228_21425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BS21228_21430	COG0527	aspartate kinase activity
BS21228_21435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS21228_21440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS21228_21445	COG0740	serine-type endopeptidase activity
BS21228_21455	COG1674	ftsk spoiiie
BS21228_21455	COG4980	gas vesicle protein
BS21228_21460	COG2188	Transcriptional regulator
BS21228_21465	COG2814	Major facilitator Superfamily
BS21228_21470	COG0612	Peptidase, M16
BS21228_21475	COG0612	Peptidase, M16
BS21228_21480	COG0300	oxidoreductase activity
BS21228_21495	COG1426	Protein conserved in bacteria
BS21228_21500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BS21228_21505	COG1546	Belongs to the CinA family
BS21228_21505	COG1058	Belongs to the CinA family
BS21228_21510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BS21228_21515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS21228_21520	COG1418	mRNA catabolic process
BS21228_21525	COG1692	metallophosphoesterase
BS21228_21530	COG2359	stage V sporulation protein S
BS21228_21535	COG1063	alcohol dehydrogenase
BS21228_21540	COG0156	8-amino-7-oxononanoate synthase activity
BS21228_21545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS21228_21550	COG4550	Control of competence regulator ComK, YlbF/YmcA
BS21228_21560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BS21228_21565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BS21228_21665	COG3226	Transcriptional regulator
BS21228_21675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_21680	COG1404	Belongs to the peptidase S8 family
BS21228_21690	COG4195	phage-related replication protein
BS21228_21695	COG1764	response to oxidative stress
BS21228_21700	COG2076	Multidrug Resistance protein
BS21228_21705	COG2076	Multidrug Resistance protein
BS21228_21720	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BS21228_21725	COG1923	regulation of RNA biosynthetic process
BS21228_21740	COG1780	Probably involved in ribonucleotide reductase function
BS21228_21745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS21228_21750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS21228_21755	COG4112	unkown
BS21228_21760	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_21770	COG0464	growth
BS21228_21775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BS21228_21780	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BS21228_21785	COG0789	Transcriptional regulator
BS21228_21790	COG0174	glutamine synthetase
BS21228_21795	COG4974	Belongs to the 'phage' integrase family
BS21228_21815	COG3645	SOS response
BS21228_21815	COG3646	Phage regulatory protein
BS21228_21960	COG3953	SLT domain
BS21228_21960	COG5412	phage tail tape measure protein
BS21228_22005	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_22005	COG1388	LysM domain
BS21228_22005	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_22015	COG5444	nuclease activity
BS21228_22055	COG1525	nuclease
BS21228_22160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS21228_22210	COG0457	Tetratricopeptide repeat
BS21228_22345	COG3883	PFAM NLP P60 protein
BS21228_22345	COG0791	NLP P60 protein
BS21228_22400	COG0629	single-stranded DNA binding
BS21228_22415	COG0582	viral genome integration into host DNA
BS21228_22445	COG1793	dna ligase
BS21228_22460	COG1525	nuclease