locus-tag	class	description
BsBEST3095_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BsBEST3095_00020	COG0592	DNA-directed DNA polymerase activity
BsBEST3095_00030	COG2501	S4 domain
BsBEST3095_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BsBEST3095_00060	COG0187	DNA topoisomerase II activity
BsBEST3095_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3095_00090	COG0516	GMP reductase activity
BsBEST3095_00090	COG0517	IMP dehydrogenase activity
BsBEST3095_00100	COG1686	Belongs to the peptidase S11 family
BsBEST3095_00110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BsBEST3095_00120	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BsBEST3095_00130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BsBEST3095_00140	COG1428	Deoxynucleoside kinase
BsBEST3095_00150	COG1428	Deoxynucleoside kinase
BsBEST3095_00160	COG1388	LysM domain
BsBEST3095_00160	COG3858	chitin binding
BsBEST3095_00170	COG1335	isochorismatase
BsBEST3095_00180	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3095_00190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BsBEST3095_00200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BsBEST3095_00210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BsBEST3095_00250	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BsBEST3095_00260	COG3853	Toxic anion resistance protein (TelA)
BsBEST3095_00270	COG1982	Orn Lys Arg decarboxylase major
BsBEST3095_00280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3095_00290	COG3870	Protein conserved in bacteria
BsBEST3095_00300	COG1728	Protein conserved in bacteria
BsBEST3095_00310	COG0470	DNA polymerase III
BsBEST3095_00320	COG1774	PSP1 C-terminal conserved region
BsBEST3095_00330	COG4467	Involved in initiation control of chromosome replication
BsBEST3095_00340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BsBEST3095_00350	COG2827	Endonuclease containing a URI domain
BsBEST3095_00360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BsBEST3095_00370	COG2002	toxin-antitoxin pair type II binding
BsBEST3095_00380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3095_00380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3095_00390	COG0084	hydrolase, TatD family'
BsBEST3095_00400	COG3584	3D domain protein
BsBEST3095_00400	COG3583	domain protein
BsBEST3095_00410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3095_00420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BsBEST3095_00440	COG4466	Protein conserved in bacteria
BsBEST3095_00460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BsBEST3095_00470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3095_00480	COG0251	oxidation-reduction process
BsBEST3095_00490	COG2088	sporulation resulting in formation of a cellular spore
BsBEST3095_00500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BsBEST3095_00510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BsBEST3095_00520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BsBEST3095_00530	COG0193	aminoacyl-tRNA hydrolase activity
BsBEST3095_00550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BsBEST3095_00560	COG2002	toxin-antitoxin pair type II binding
BsBEST3095_00570	COG2244	polysaccharide biosynthetic process
BsBEST3095_00580	COG3956	TIGRFAM MazG family protein
BsBEST3095_00590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BsBEST3095_00620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BsBEST3095_00630	COG1098	S1 RNA binding domain
BsBEST3095_00640	COG2208	phosphoserine phosphatase activity
BsBEST3095_00650	COG2304	oxidoreductase activity
BsBEST3095_00660	COG0515	serine threonine protein kinase
BsBEST3095_00670	COG0037	tRNA processing
BsBEST3095_00680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BsBEST3095_00690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3095_00700	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BsBEST3095_00710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BsBEST3095_00720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3095_00730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3095_00740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3095_00750	COG0512	Glutamine amidotransferase of anthranilate synthase
BsBEST3095_00760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3095_00770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BsBEST3095_00780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BsBEST3095_00790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BsBEST3095_00800	COG1396	sequence-specific DNA binding
BsBEST3095_00810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3095_00820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BsBEST3095_00830	COG4463	regulation of RNA biosynthetic process
BsBEST3095_00840	COG3880	PFAM UvrB UvrC protein
BsBEST3095_00850	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BsBEST3095_00860	COG0542	response to heat
BsBEST3095_00870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BsBEST3095_00880	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BsBEST3095_00890	COG4956	integral membrane protein (PIN domain superfamily)
BsBEST3095_00900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BsBEST3095_00910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BsBEST3095_00920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BsBEST3095_00930	COG1045	serine acetyltransferase
BsBEST3095_00940	COG0215	cysteine-tRNA ligase activity
BsBEST3095_00950	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BsBEST3095_00960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3095_00970	COG3688	RNA-binding protein containing a PIN domain
BsBEST3095_00980	COG1595	DNA-templated transcription, initiation
BsBEST3095_00990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3095_01000	COG0250	Participates in transcription elongation, termination and antitermination
BsBEST3095_01020	COG0081	regulation of translation
BsBEST3095_01030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BsBEST3095_01050	COG2813	Specifically methylates the guanine in position
BsBEST3095_01060	COG0085	RNA polymerase activity
BsBEST3095_01070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BsBEST3095_01080	COG1358	cellular component organization or biogenesis
BsBEST3095_01090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BsBEST3095_01100	COG0049	tRNA binding
BsBEST3095_01110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BsBEST3095_01120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BsBEST3095_01130	COG0596	Alpha beta hydrolase
BsBEST3095_01150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BsBEST3095_01160	COG0088	Forms part of the polypeptide exit tunnel
BsBEST3095_01180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BsBEST3095_01210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BsBEST3095_01220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BsBEST3095_01240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BsBEST3095_01250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BsBEST3095_01270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BsBEST3095_01290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BsBEST3095_01300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BsBEST3095_01310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BsBEST3095_01340	COG0200	Binds to the 23S rRNA
BsBEST3095_01350	COG0201	protein transport
BsBEST3095_01360	COG0563	adenylate kinase activity
BsBEST3095_01370	COG0024	Methionine aminopeptidase
BsBEST3095_01390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BsBEST3095_01400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BsBEST3095_01410	COG0202	RNA polymerase activity
BsBEST3095_01420	COG0203	ribosomal protein L17
BsBEST3095_01430	COG1122	ATPase activity
BsBEST3095_01440	COG1122	ATPase activity
BsBEST3095_01450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3095_01460	COG0101	tRNA pseudouridine synthase activity
BsBEST3095_01470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BsBEST3095_01480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BsBEST3095_01490	COG2226	methyltransferase
BsBEST3095_01510	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_01520	COG0489	protein tyrosine kinase activity
BsBEST3095_01540	COG2194	sulfuric ester hydrolase activity
BsBEST3095_01550	COG0726	polysaccharide deacetylase
BsBEST3095_01560	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3095_01580	COG0385	Bile acid
BsBEST3095_01590	COG2819	hydrolase of the alpha beta superfamily
BsBEST3095_01600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3095_01610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3095_01620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3095_01630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3095_01630	COG2207	Transcriptional regulator
BsBEST3095_01640	COG3876	Protein conserved in bacteria
BsBEST3095_01650	COG1472	Belongs to the glycosyl hydrolase 3 family
BsBEST3095_01660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3095_01670	COG1263	PTS System
BsBEST3095_01670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3095_01680	COG1737	Transcriptional regulator
BsBEST3095_01690	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BsBEST3095_01700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3095_01710	COG1683	Conserved Protein
BsBEST3095_01720	COG1595	DNA-templated transcription, initiation
BsBEST3095_01730	COG5662	AntiSigma factor
BsBEST3095_01740	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3095_01750	COG4856	YbbR-like protein
BsBEST3095_01760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3095_01770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BsBEST3095_01790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3095_01800	COG2169	Transcriptional regulator
BsBEST3095_01810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3095_01820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3095_01830	COG3002	Belongs to the UPF0753 family
BsBEST3095_01840	COG0288	reversible hydration of carbon dioxide
BsBEST3095_01860	COG5609	conserved protein (DUF2294)
BsBEST3095_01880	COG0640	Transcriptional regulator
BsBEST3095_01890	COG2814	Major facilitator Superfamily
BsBEST3095_01910	COG0535	radical SAM domain protein
BsBEST3095_01920	COG1266	CAAX protease self-immunity
BsBEST3095_01930	COG1131	(ABC) transporter
BsBEST3095_01950	COG1413	lyase activity
BsBEST3095_01960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_01970	COG0596	Alpha beta hydrolase
BsBEST3095_01980	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_01990	COG0642	Histidine kinase
BsBEST3095_02010	COG0515	serine threonine protein kinase
BsBEST3095_02040	COG1113	amino acid transport
BsBEST3095_02070	COG2602	Beta-lactamase
BsBEST3095_02080	COG2124	cytochrome p450
BsBEST3095_02100	COG0531	amino acid
BsBEST3095_02110	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3095_02120	COG2271	Major facilitator Superfamily
BsBEST3095_02140	COG0456	acetyltransferase
BsBEST3095_02140	COG1846	Transcriptional regulator
BsBEST3095_02150	COG2271	Major facilitator Superfamily
BsBEST3095_02180	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_02190	COG0697	spore germination
BsBEST3095_02200	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3095_02200	COG2207	Transcriptional regulator
BsBEST3095_02210	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BsBEST3095_02220	COG3591	Belongs to the peptidase S1B family
BsBEST3095_02240	COG0596	Alpha beta hydrolase
BsBEST3095_02250	COG1183	phosphatidylcholine synthase activity
BsBEST3095_02260	COG0586	Pfam SNARE associated Golgi protein
BsBEST3095_02270	COG0688	phosphatidylethanolamine metabolic process
BsBEST3095_02290	COG2312	Erythromycin esterase
BsBEST3095_02300	COG2207	Transcriptional regulator
BsBEST3095_02310	COG1054	Belongs to the UPF0176 family
BsBEST3095_02320	COG1301	dicarboxylic acid transport
BsBEST3095_02330	COG1263	PTS System
BsBEST3095_02330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3095_02330	COG2190	(PTS) system
BsBEST3095_02340	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3095_02350	COG2188	Transcriptional regulator
BsBEST3095_02370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3095_02380	COG0833	amino acid
BsBEST3095_02390	COG2040	homocysteine
BsBEST3095_02400	COG1115	amino acid carrier protein
BsBEST3095_02410	COG2066	Belongs to the glutaminase family
BsBEST3095_02420	COG4191	Histidine kinase
BsBEST3095_02430	COG0784	Response regulator, receiver
BsBEST3095_02440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3095_02450	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_02460	COG2271	Major facilitator Superfamily
BsBEST3095_02470	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3095_02480	COG2186	Transcriptional regulator
BsBEST3095_02490	COG2721	sulfolactate sulfo-lyase activity
BsBEST3095_02500	COG3173	Aminoglycoside phosphotransferase
BsBEST3095_02520	COG0697	spore germination
BsBEST3095_02530	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_02540	COG2205	protein histidine kinase activity
BsBEST3095_02550	COG1131	(ABC) transporter
BsBEST3095_02580	COG3773	Cell wall hydrolase
BsBEST3095_02590	COG2304	oxidoreductase activity
BsBEST3095_02600	COG3540	Alkaline phosphatase
BsBEST3095_02610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3095_02620	COG0805	protein transport
BsBEST3095_02630	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BsBEST3095_02640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3095_02650	COG0477	Major facilitator Superfamily
BsBEST3095_02660	COG1309	transcriptional regulator
BsBEST3095_02670	COG0252	asparaginase activity
BsBEST3095_02680	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3095_02690	COG1714	RDD family
BsBEST3095_02700	COG1405	negative regulation of cell septum assembly
BsBEST3095_02700	COG3012	SEC-C Motif Domain Protein
BsBEST3095_02710	COG3290	protein histidine kinase activity
BsBEST3095_02720	COG3279	Response regulator of the LytR AlgR family
BsBEST3095_02730	COG4555	ABC transporter
BsBEST3095_02740	COG1668	transmembrane transport
BsBEST3095_02750	COG0667	Aldo Keto reductase
BsBEST3095_02770	COG1595	DNA-templated transcription, initiation
BsBEST3095_02780	COG1595	DNA-templated transcription, initiation
BsBEST3095_02790	COG1876	peptidase activity
BsBEST3095_02800	COG0457	Tetratricopeptide repeat
BsBEST3095_02810	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_02820	COG0366	Alpha amylase catalytic
BsBEST3095_02830	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3095_02840	COG1121	(ABC) transporter
BsBEST3095_02850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3095_02860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3095_02870	COG2310	stress, protein
BsBEST3095_02880	COG2310	stress, protein
BsBEST3095_02890	COG2310	stress, protein
BsBEST3095_02900	COG0861	Integral membrane protein TerC family
BsBEST3095_02920	COG3853	Toxic anion resistance protein (TelA)
BsBEST3095_02930	COG0477	Major facilitator Superfamily
BsBEST3095_02940	COG2814	Major facilitator Superfamily
BsBEST3095_02950	COG0640	Transcriptional regulator
BsBEST3095_02960	COG0517	IMP dehydrogenase activity
BsBEST3095_02960	COG4175	Glycine betaine
BsBEST3095_02970	COG4176	ABC-type proline glycine betaine transport system permease component
BsBEST3095_02980	COG2113	Glycine betaine
BsBEST3095_02990	COG1473	amidohydrolase
BsBEST3095_03000	COG1288	antiporter activity
BsBEST3095_03020	COG0366	Alpha amylase catalytic
BsBEST3095_03030	COG0039	L-malate dehydrogenase activity
BsBEST3095_03040	COG1620	l-lactate permease
BsBEST3095_03050	COG2814	Major facilitator Superfamily
BsBEST3095_03060	COG1846	Transcriptional regulator
BsBEST3095_03070	COG1280	lysine exporter protein (LysE YggA)
BsBEST3095_03080	COG3403	YqcI/YcgG family
BsBEST3095_03090	COG1113	amino acid transport
BsBEST3095_03100	COG3665	Urea carboxylase-associated protein
BsBEST3095_03110	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BsBEST3095_03120	COG1660	Displays ATPase and GTPase activities
BsBEST3095_03130	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BsBEST3095_03140	COG2226	methyltransferase
BsBEST3095_03150	COG0583	DNA-binding transcription factor activity
BsBEST3095_03160	COG3458	cephalosporin-C deacetylase activity
BsBEST3095_03170	COG3541	Predicted nucleotidyltransferase
BsBEST3095_03180	COG0506	proline dehydrogenase activity
BsBEST3095_03190	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_03200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3095_03210	COG2508	Transcriptional regulator
BsBEST3095_03220	COG3689	TIGRFAM TIGR03943 family protein
BsBEST3095_03230	COG0701	Predicted permease
BsBEST3095_03240	COG2267	carboxylic ester hydrolase activity
BsBEST3095_03250	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3095_03260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3095_03260	COG1587	Uroporphyrinogen-III synthase
BsBEST3095_03270	COG2146	nitrite reductase [NAD(P)H] activity
BsBEST3095_03280	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3095_03290	COG0243	molybdopterin cofactor binding
BsBEST3095_03300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3095_03310	COG2223	nitrite transmembrane transporter activity
BsBEST3095_03320	COG1469	GTP cyclohydrolase I activity
BsBEST3095_03330	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3095_03340	COG0523	cobalamin synthesis protein
BsBEST3095_03350	COG0765	amino acid transport
BsBEST3095_03360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3095_03380	COG1714	RDD family
BsBEST3095_03400	COG2723	6-phospho-beta-galactosidase activity
BsBEST3095_03420	COG3209	COG3209 Rhs family protein
BsBEST3095_03430	COG3290	protein histidine kinase activity
BsBEST3095_03430	COG0840	transmembrane signaling receptor activity
BsBEST3095_03440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BsBEST3095_03450	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BsBEST3095_03460	COG1733	regulation of RNA biosynthetic process
BsBEST3095_03470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_03480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_03490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_03500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_03510	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BsBEST3095_03520	COG2814	Major facilitator Superfamily
BsBEST3095_03540	COG0697	spore germination
BsBEST3095_03550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3095_03580	COG2364	Membrane
BsBEST3095_03590	COG1126	abc transporter atp-binding protein
BsBEST3095_03600	COG0765	amino acid transport
BsBEST3095_03610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3095_03620	COG0583	DNA-binding transcription factor activity
BsBEST3095_03630	COG0163	prenyltransferase activity
BsBEST3095_03640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BsBEST3095_03670	COG0596	Alpha beta hydrolase
BsBEST3095_03680	COG3104	oligopeptide transport
BsBEST3095_03690	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3095_03710	COG0697	spore germination
BsBEST3095_03730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3095_03740	COG1136	(ABC) transporter
BsBEST3095_03750	COG0577	efflux transmembrane transporter activity
BsBEST3095_03760	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_03770	COG5002	protein histidine kinase activity
BsBEST3095_03770	COG3850	Histidine kinase
BsBEST3095_03780	COG0457	Tetratricopeptide repeat
BsBEST3095_03800	COG0527	aspartate kinase activity
BsBEST3095_03810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3095_03820	COG4605	iron ion homeostasis
BsBEST3095_03830	COG4604	ABC transporter, ATP-binding protein
BsBEST3095_03840	COG4607	ABC-type enterochelin transport system periplasmic component
BsBEST3095_03850	COG2814	Major facilitator Superfamily
BsBEST3095_03860	COG1309	transcriptional regulator
BsBEST3095_03870	COG0778	Nitroreductase
BsBEST3095_03880	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3095_03890	COG0640	Transcriptional regulator
BsBEST3095_03900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3095_03910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BsBEST3095_03920	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_03930	COG4975	Glucose uptake
BsBEST3095_03940	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_03950	COG4549	nuclear export factor GLE1
BsBEST3095_03960	COG1276	copper resistance
BsBEST3095_03960	COG2372	response to copper ion
BsBEST3095_03970	COG1349	DNA-binding transcription factor activity
BsBEST3095_03990	COG2213	PTS system mannitol-specific
BsBEST3095_04000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3095_04010	COG0246	Mannitol dehydrogenase
BsBEST3095_04020	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3095_04040	COG0681	Belongs to the peptidase S26 family
BsBEST3095_04050	COG0412	Dienelactone hydrolase
BsBEST3095_04060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3095_04080	COG0561	phosphatase activity
BsBEST3095_04090	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3095_04100	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3095_04110	COG4336	lyase activity
BsBEST3095_04120	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3095_04130	COG1984	allophanate hydrolase subunit 2
BsBEST3095_04140	COG1414	Transcriptional regulator
BsBEST3095_04150	COG2755	lipolytic protein G-D-S-L family
BsBEST3095_04170	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3095_04180	COG0768	penicillin binding
BsBEST3095_04190	COG4989	oxidoreductase activity
BsBEST3095_04200	COG3711	transcriptional antiterminator
BsBEST3095_04210	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3095_04220	COG2226	methyltransferase
BsBEST3095_04230	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_04240	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3095_04250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3095_04260	COG3871	stress protein (general stress protein 26)
BsBEST3095_04280	COG2814	Major facilitator Superfamily
BsBEST3095_04290	COG1522	sequence-specific DNA binding
BsBEST3095_04300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3095_04300	COG0551	DNA topoisomerase type I activity
BsBEST3095_04310	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BsBEST3095_04320	COG3706	GGDEF domain
BsBEST3095_04330	COG5298	Protein conserved in bacteria
BsBEST3095_04340	COG1215	transferase activity, transferring glycosyl groups
BsBEST3095_04360	COG0531	amino acid
BsBEST3095_04370	COG0494	nUDIX hydrolase
BsBEST3095_04380	COG0028	Belongs to the TPP enzyme family
BsBEST3095_04410	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3095_04420	COG2261	transglycosylase associated protein
BsBEST3095_04430	COG4876	unkown
BsBEST3095_04440	COG2217	Heavy metal translocating P-type atpase
BsBEST3095_04450	COG3729	General stress protein
BsBEST3095_04460	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3095_04470	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3095_04480	COG3546	catalase activity
BsBEST3095_04490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BsBEST3095_04500	COG3290	protein histidine kinase activity
BsBEST3095_04510	COG4565	transcriptional regulatory protein
BsBEST3095_04520	COG1301	dicarboxylic acid transport
BsBEST3095_04530	COG0628	permease
BsBEST3095_04540	COG1131	(ABC) transporter
BsBEST3095_04550	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3095_04570	COG1960	acyl-CoA dehydrogenase activity
BsBEST3095_04600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3095_04610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_04620	COG1181	Belongs to the D-alanine--D-alanine ligase family
BsBEST3095_04630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BsBEST3095_04640	COG0513	Belongs to the DEAD box helicase family
BsBEST3095_04650	COG3402	PFAM membrane-flanked domain
BsBEST3095_04660	COG3428	Bacterial PH domain
BsBEST3095_04670	COG0705	Rhomboid family
BsBEST3095_04680	COG0736	holo-[acyl-carrier-protein] synthase activity
BsBEST3095_04690	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BsBEST3095_04700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3095_04710	COG0864	Transcriptional regulator
BsBEST3095_04720	COG2337	Toxic component of a toxin-antitoxin (TA) module
BsBEST3095_04730	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3095_04740	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3095_04750	COG2172	sigma factor antagonist activity
BsBEST3095_04760	COG2208	phosphoserine phosphatase activity
BsBEST3095_04770	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3095_04780	COG2172	sigma factor antagonist activity
BsBEST3095_04790	COG1191	sigma factor activity
BsBEST3095_04800	COG2208	phosphoserine phosphatase activity
BsBEST3095_04830	COG1673	EVE domain
BsBEST3095_04840	COG1846	Transcriptional regulator
BsBEST3095_04850	COG2183	response to ionizing radiation
BsBEST3095_04860	COG3091	SprT-like family
BsBEST3095_04870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3095_04880	COG1522	sequence-specific DNA binding
BsBEST3095_04890	COG1522	sequence-specific DNA binding
BsBEST3095_04900	COG1335	isochorismatase
BsBEST3095_04910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3095_04920	COG2814	Major facilitator Superfamily
BsBEST3095_04960	COG0693	protein deglycase activity
BsBEST3095_04970	COG1278	Cold shock
BsBEST3095_04980	COG1329	Transcriptional regulator
BsBEST3095_04990	COG0697	spore germination
BsBEST3095_05000	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3095_05000	COG2207	Transcriptional regulator
BsBEST3095_05010	COG0697	spore germination
BsBEST3095_05020	COG2207	Transcriptional regulator
BsBEST3095_05020	COG3708	Transcriptional regulator
BsBEST3095_05030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3095_05040	COG0477	Major facilitator Superfamily
BsBEST3095_05060	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BsBEST3095_05080	COG0697	spore germination
BsBEST3095_05090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3095_05100	COG2030	dehydratase
BsBEST3095_05110	COG3545	Serine hydrolase
BsBEST3095_05120	COG1733	regulation of RNA biosynthetic process
BsBEST3095_05130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3095_05140	COG1733	regulation of RNA biosynthetic process
BsBEST3095_05150	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3095_05160	COG2814	Major facilitator Superfamily
BsBEST3095_05170	COG1309	transcriptional regulator
BsBEST3095_05190	COG0640	Transcriptional regulator
BsBEST3095_05200	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3095_05210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3095_05220	COG0697	spore germination
BsBEST3095_05230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3095_05240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3095_05250	COG0640	Transcriptional regulator
BsBEST3095_05260	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3095_05280	COG4585	Histidine kinase
BsBEST3095_05290	COG2197	response regulator
BsBEST3095_05300	COG2409	Drug exporters of the RND superfamily
BsBEST3095_05310	COG0596	Alpha beta hydrolase
BsBEST3095_05320	COG1811	Na channel or pump
BsBEST3095_05330	COG0789	Transcriptional regulator
BsBEST3095_05330	COG4978	Transcriptional regulator
BsBEST3095_05340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3095_05350	COG0778	Nitroreductase
BsBEST3095_05360	COG0346	lactoylglutathione lyase activity
BsBEST3095_05370	COG2259	Doxx family
BsBEST3095_05380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_05410	COG2323	membrane
BsBEST3095_05420	COG2323	membrane
BsBEST3095_05430	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3095_05460	COG1309	transcriptional regulator
BsBEST3095_05480	COG0456	acetyltransferase
BsBEST3095_05490	COG0488	(ABC) transporter
BsBEST3095_05500	COG1113	amino acid transport
BsBEST3095_05510	COG2318	DinB family
BsBEST3095_05520	COG1846	Transcriptional regulator
BsBEST3095_05530	COG1033	growth of symbiont in host cell
BsBEST3095_05530	COG2409	Drug exporters of the RND superfamily
BsBEST3095_05540	COG0778	Nitroreductase
BsBEST3095_05550	COG1846	Transcriptional regulator
BsBEST3095_05560	COG2814	Major facilitator Superfamily
BsBEST3095_05570	COG0730	response to heat
BsBEST3095_05580	COG1802	Transcriptional regulator
BsBEST3095_05590	COG1388	LysM domain
BsBEST3095_05590	COG3858	chitin binding
BsBEST3095_05600	COG1819	glycosyl
BsBEST3095_05620	COG1785	Belongs to the alkaline phosphatase family
BsBEST3095_05630	COG5646	InterPro IPR014922
BsBEST3095_05650	COG0454	-acetyltransferase
BsBEST3095_05660	COG1078	dGTPase activity
BsBEST3095_05670	COG1388	LysM domain
BsBEST3095_05680	COG2814	Major facilitator Superfamily
BsBEST3095_05690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3095_05700	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3095_05710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3095_05720	COG2723	6-phospho-beta-galactosidase activity
BsBEST3095_05730	COG2188	Transcriptional regulator
BsBEST3095_05740	COG1940	carbohydrate kinase activity
BsBEST3095_05750	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3095_05760	COG4124	Belongs to the glycosyl hydrolase 26 family
BsBEST3095_05790	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BsBEST3095_05800	COG0802	atpase or kinase
BsBEST3095_05810	COG1214	PFAM Peptidase M22, glycoprotease
BsBEST3095_05820	COG0456	acetyltransferase
BsBEST3095_05830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BsBEST3095_05840	COG0488	(ABC) transporter
BsBEST3095_05850	COG0315	cyclic pyranopterin monophosphate synthase activity
BsBEST3095_05860	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BsBEST3095_05870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3095_05880	COG0805	protein transport
BsBEST3095_05900	COG1266	CAAX protease self-immunity
BsBEST3095_05920	COG0459	protein refolding
BsBEST3095_05950	COG3378	Phage plasmid primase P4 family
BsBEST3095_05980	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3095_05990	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3095_06020	COG1401	restriction endodeoxyribonuclease activity
BsBEST3095_06070	COG1073	alpha beta
BsBEST3095_06080	COG0457	Tetratricopeptide repeat
BsBEST3095_06090	COG1063	alcohol dehydrogenase
BsBEST3095_06100	COG2211	Major facilitator Superfamily
BsBEST3095_06110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3095_06120	COG1842	Phage shock protein A
BsBEST3095_06130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3095_06140	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BsBEST3095_06150	COG4260	virion core protein, lumpy skin disease virus
BsBEST3095_06170	COG2814	Major facilitator Superfamily
BsBEST3095_06180	COG1063	alcohol dehydrogenase
BsBEST3095_06190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BsBEST3095_06200	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3095_06230	COG2267	carboxylic ester hydrolase activity
BsBEST3095_06250	COG2132	Multicopper oxidase
BsBEST3095_06260	COG1113	amino acid transport
BsBEST3095_06270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3095_06280	COG0714	Associated with various cellular activities
BsBEST3095_06290	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BsBEST3095_06300	COG1305	Transglutaminase-like
BsBEST3095_06310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BsBEST3095_06310	COG0519	Catalyzes the synthesis of GMP from XMP
BsBEST3095_06320	COG2252	PERMEase
BsBEST3095_06330	COG3064	Membrane
BsBEST3095_06350	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BsBEST3095_06370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BsBEST3095_06380	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BsBEST3095_06390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BsBEST3095_06400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BsBEST3095_06410	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3095_06420	COG0047	phosphoribosylformylglycinamidine synthase activity
BsBEST3095_06430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3095_06440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BsBEST3095_06450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BsBEST3095_06460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BsBEST3095_06470	COG0138	bifunctional purine biosynthesis protein purh
BsBEST3095_06480	COG0151	Belongs to the GarS family
BsBEST3095_06490	COG1522	sequence-specific DNA binding
BsBEST3095_06500	COG0531	amino acid
BsBEST3095_06520	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3095_06530	COG1470	cell adhesion involved in biofilm formation
BsBEST3095_06540	COG4496	protein, YerC YecD
BsBEST3095_06550	COG0069	glutamate synthase activity
BsBEST3095_06560	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BsBEST3095_06570	COG0210	DNA helicase
BsBEST3095_06580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BsBEST3095_06590	COG4851	CamS sex pheromone cAM373 precursor
BsBEST3095_06600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3095_06610	COG1285	pathogenesis
BsBEST3095_06620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3095_06630	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3095_06640	COG0154	amidase activity
BsBEST3095_06650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3095_06660	COG1309	transcriptional regulator
BsBEST3095_06670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BsBEST3095_06680	COG1597	lipid kinase activity
BsBEST3095_06690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3095_06700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3095_06710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3095_06720	COG1002	Type II restriction enzyme, methylase subunits
BsBEST3095_06730	COG1061	Type III restriction enzyme res subunit
BsBEST3095_06740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BsBEST3095_06780	COG5444	nuclease activity
BsBEST3095_06800	COG3391	amine dehydrogenase activity
BsBEST3095_06810	COG0457	Tetratricopeptide repeat
BsBEST3095_06830	COG0217	transcriptional regulatory protein
BsBEST3095_06850	COG1309	transcriptional regulator
BsBEST3095_06860	COG3631	Ketosteroid isomerase-related protein
BsBEST3095_06870	COG0702	epimerase
BsBEST3095_06900	COG3546	catalase activity
BsBEST3095_06910	COG0454	-acetyltransferase
BsBEST3095_06930	COG5578	integral membrane protein
BsBEST3095_06940	COG2972	Histidine kinase
BsBEST3095_06950	COG2207	Transcriptional regulator
BsBEST3095_06950	COG4753	response regulator
BsBEST3095_06960	COG1653	transport
BsBEST3095_06970	COG1175	transmembrane transport
BsBEST3095_06980	COG0395	ABC-type sugar transport system, permease component
BsBEST3095_06990	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3095_07000	COG2207	Transcriptional regulator
BsBEST3095_07010	COG2755	lipolytic protein G-D-S-L family
BsBEST3095_07030	COG5578	integral membrane protein
BsBEST3095_07040	COG3401	FG-GAP repeat protein
BsBEST3095_07050	COG3401	FG-GAP repeat protein
BsBEST3095_07060	COG2755	lipolytic protein G-D-S-L family
BsBEST3095_07070	COG1874	Beta-galactosidase
BsBEST3095_07090	COG1653	transport
BsBEST3095_07100	COG4209	transmembrane transport
BsBEST3095_07110	COG0395	ABC-type sugar transport system, permease component
BsBEST3095_07120	COG1486	melibiose metabolic process
BsBEST3095_07130	COG2323	membrane
BsBEST3095_07140	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3095_07150	COG0346	lactoylglutathione lyase activity
BsBEST3095_07170	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3095_07190	COG5583	Uncharacterized small protein (DUF2292)
BsBEST3095_07200	COG0670	Belongs to the BI1 family
BsBEST3095_07210	COG0697	spore germination
BsBEST3095_07220	COG1846	Transcriptional regulator
BsBEST3095_07230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3095_07250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3095_07250	COG2124	cytochrome p450
BsBEST3095_07260	COG1368	sulfuric ester hydrolase activity
BsBEST3095_07270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BsBEST3095_07280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3095_07290	COG1442	glycosyl transferase family 8
BsBEST3095_07300	COG1216	Glycosyl transferase, family 2
BsBEST3095_07310	COG1442	glycosyl transferase family 8
BsBEST3095_07320	COG2223	nitrite transmembrane transporter activity
BsBEST3095_07330	COG1011	Hydrolase
BsBEST3095_07340	COG0531	amino acid
BsBEST3095_07350	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_07360	COG0840	transmembrane signaling receptor activity
BsBEST3095_07370	COG0488	(ABC) transporter
BsBEST3095_07390	COG0789	Transcriptional regulator
BsBEST3095_07400	COG2814	Major facilitator Superfamily
BsBEST3095_07420	COG0488	(ABC) transporter
BsBEST3095_07430	COG0513	Belongs to the DEAD box helicase family
BsBEST3095_07440	COG0456	acetyltransferase
BsBEST3095_07450	COG2130	NADP-dependent
BsBEST3095_07470	COG2211	Major facilitator Superfamily
BsBEST3095_07480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BsBEST3095_07490	COG1120	ATPase activity
BsBEST3095_07500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3095_07510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3095_07520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3095_07550	COG3866	Pectate lyase
BsBEST3095_07560	COG0471	metal ion transport
BsBEST3095_07570	COG3290	protein histidine kinase activity
BsBEST3095_07580	COG4565	transcriptional regulatory protein
BsBEST3095_07590	COG3181	Tripartite tricarboxylate transporter family receptor
BsBEST3095_07600	COG2851	Citrate transporter
BsBEST3095_07610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3095_07620	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BsBEST3095_07630	COG1254	Belongs to the acylphosphatase family
BsBEST3095_07640	COG2258	MOSC domain
BsBEST3095_07680	COG0024	Methionine aminopeptidase
BsBEST3095_07690	COG1263	PTS System
BsBEST3095_07690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3095_07700	COG1368	sulfuric ester hydrolase activity
BsBEST3095_07720	COG1115	amino acid carrier protein
BsBEST3095_07730	COG0531	amino acid
BsBEST3095_07760	COG0697	spore germination
BsBEST3095_07770	COG1263	PTS System
BsBEST3095_07770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3095_07780	COG0366	Alpha amylase catalytic
BsBEST3095_07790	COG2188	Transcriptional regulator
BsBEST3095_07800	COG0778	Nitroreductase
BsBEST3095_07810	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3095_07820	COG0693	protein deglycase activity
BsBEST3095_07830	COG2814	Major facilitator Superfamily
BsBEST3095_07840	COG4840	Belongs to the UPF0435 family
BsBEST3095_07850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3095_07860	COG4980	gas vesicle protein
BsBEST3095_07870	COG1295	ribonuclease BN
BsBEST3095_07880	COG0477	Major facilitator Superfamily
BsBEST3095_07890	COG0387	Pfam Sodium calcium exchanger
BsBEST3095_07910	COG0668	transmembrane transport
BsBEST3095_07920	COG0535	radical SAM domain protein
BsBEST3095_07940	COG0726	polysaccharide deacetylase
BsBEST3095_07950	COG2084	Dehydrogenase
BsBEST3095_07960	COG0598	Magnesium transport protein CorA
BsBEST3095_07970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3095_07980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3095_08000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3095_08010	COG4637	Psort location Cytoplasmic, score
BsBEST3095_08030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3095_08040	COG0022	dehydrogenase e1 component
BsBEST3095_08050	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3095_08060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3095_08070	COG3284	Transcriptional regulator
BsBEST3095_08090	COG1742	UPF0060 membrane protein
BsBEST3095_08140	COG4842	Belongs to the WXG100 family
BsBEST3095_08150	COG1486	melibiose metabolic process
BsBEST3095_08160	COG1737	Transcriptional regulator
BsBEST3095_08170	COG1263	PTS System
BsBEST3095_08170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3095_08180	COG1132	(ABC) transporter
BsBEST3095_08190	COG1132	(ABC) transporter
BsBEST3095_08200	COG2259	Doxx family
BsBEST3095_08210	COG2514	catechol 2,3-dioxygenase activity
BsBEST3095_08220	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3095_08220	COG4977	sequence-specific DNA binding
BsBEST3095_08230	COG2814	Major facilitator Superfamily
BsBEST3095_08240	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3095_08250	COG0673	inositol 2-dehydrogenase activity
BsBEST3095_08260	COG4585	Histidine kinase
BsBEST3095_08270	COG2197	response regulator
BsBEST3095_08280	COG1131	(ABC) transporter
BsBEST3095_08290	COG0842	Transport permease protein
BsBEST3095_08290	COG1511	domain protein
BsBEST3095_08300	COG0842	Transport permease protein
BsBEST3095_08310	COG1695	Transcriptional regulator
BsBEST3095_08320	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3095_08330	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BsBEST3095_08340	COG1309	transcriptional regulator
BsBEST3095_08350	COG2814	Major facilitator Superfamily
BsBEST3095_08360	COG2318	DinB family
BsBEST3095_08370	COG2814	Major facilitator Superfamily
BsBEST3095_08380	COG1846	Transcriptional regulator
BsBEST3095_08390	COG0392	lysyltransferase activity
BsBEST3095_08390	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BsBEST3095_08400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3095_08410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3095_08420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3095_08430	COG0384	phenazine biosynthesis protein PhzF
BsBEST3095_08440	COG0778	Nitroreductase
BsBEST3095_08460	COG1090	epimerase
BsBEST3095_08470	COG2137	regulation of response to DNA damage stimulus
BsBEST3095_08490	COG2814	Major facilitator Superfamily
BsBEST3095_08520	COG3103	Sh3 type 3 domain protein
BsBEST3095_08530	COG5658	integral membrane protein
BsBEST3095_08540	COG0596	Alpha beta hydrolase
BsBEST3095_08550	COG0463	Glycosyl transferase, family 2
BsBEST3095_08560	COG4485	Bacterial membrane protein, YfhO
BsBEST3095_08570	COG1988	membrane-bound metal-dependent
BsBEST3095_08580	COG1194	a g-specific adenine glycosylase
BsBEST3095_08600	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_08630	COG3557	Belongs to the UPF0374 family
BsBEST3095_08640	COG1132	(ABC) transporter
BsBEST3095_08650	COG4129	membrane
BsBEST3095_08660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3095_08670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BsBEST3095_08680	COG0735	belongs to the Fur family
BsBEST3095_08710	COG4326	sporulation control protein
BsBEST3095_08730	COG3340	Belongs to the peptidase S51 family
BsBEST3095_08740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BsBEST3095_08750	COG0277	FAD linked oxidase domain protein
BsBEST3095_08770	COG0753	catalase activity
BsBEST3095_08780	COG1116	anion transmembrane transporter activity
BsBEST3095_08790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3095_08800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3095_08810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3095_08830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BsBEST3095_08850	COG1476	TRANSCRIPTIONal
BsBEST3095_08860	COG3382	B3 4 domain protein
BsBEST3095_08870	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BsBEST3095_08890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BsBEST3095_08900	COG0789	Transcriptional regulator
BsBEST3095_08910	COG1664	Polymer-forming cytoskeletal
BsBEST3095_08920	COG1664	Polymer-forming cytoskeletal
BsBEST3095_08930	COG2766	serine protein kinase
BsBEST3095_08940	COG2718	Belongs to the UPF0229 family
BsBEST3095_08950	COG1846	Transcriptional regulator
BsBEST3095_08960	COG1566	PFAM secretion protein HlyD family protein
BsBEST3095_08970	COG2814	Major facilitator Superfamily
BsBEST3095_08980	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3095_09010	COG1725	Transcriptional regulator
BsBEST3095_09020	COG1131	(ABC) transporter
BsBEST3095_09030	COG1131	(ABC) transporter
BsBEST3095_09040	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3095_09050	COG1278	Cold shock
BsBEST3095_09060	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3095_09070	COG3706	GGDEF domain
BsBEST3095_09080	COG1823	symporter activity
BsBEST3095_09120	COG5577	PFAM Coat F domain
BsBEST3095_09130	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3095_09130	COG1525	nuclease
BsBEST3095_09130	COG4085	toxin activity
BsBEST3095_09140	COG3764	Sortase (surface protein transpeptidase)
BsBEST3095_09150	COG0564	pseudouridine synthase activity
BsBEST3095_09170	COG0517	IMP dehydrogenase activity
BsBEST3095_09180	COG0517	IMP dehydrogenase activity
BsBEST3095_09190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3095_09200	COG3153	acetyltransferase
BsBEST3095_09200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3095_09220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3095_09230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BsBEST3095_09240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BsBEST3095_09250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BsBEST3095_09260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BsBEST3095_09270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3095_09280	COG2203	Gaf domain
BsBEST3095_09280	COG4585	Histidine kinase
BsBEST3095_09290	COG2197	response regulator
BsBEST3095_09300	COG0431	NADPH-dependent FMN reductase
BsBEST3095_09330	COG0791	NLP P60 protein
BsBEST3095_09330	COG1388	LysM domain
BsBEST3095_09340	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3095_09350	COG0668	transmembrane transport
BsBEST3095_09360	COG2719	SpoVR family
BsBEST3095_09370	COG1785	Belongs to the alkaline phosphatase family
BsBEST3095_09380	COG0791	NLP P60 protein
BsBEST3095_09380	COG1388	LysM domain
BsBEST3095_09390	COG0583	DNA-binding transcription factor activity
BsBEST3095_09400	COG0372	Belongs to the citrate synthase family
BsBEST3095_09410	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_09420	COG0531	amino acid
BsBEST3095_09430	COG0733	neurotransmitter:sodium symporter activity
BsBEST3095_09440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3095_09450	COG0456	acetyltransferase
BsBEST3095_09480	COG1595	DNA-templated transcription, initiation
BsBEST3095_09490	COG0667	Aldo Keto reductase
BsBEST3095_09500	COG0204	Acyl-transferase
BsBEST3095_09510	COG1253	flavin adenine dinucleotide binding
BsBEST3095_09520	COG0789	Transcriptional regulator
BsBEST3095_09530	COG0436	Aminotransferase
BsBEST3095_09540	COG1253	flavin adenine dinucleotide binding
BsBEST3095_09550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3095_09560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3095_09570	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3095_09590	COG0668	transmembrane transport
BsBEST3095_09600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BsBEST3095_09610	COG0726	polysaccharide deacetylase
BsBEST3095_09620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3095_09630	COG1757	Na H antiporter
BsBEST3095_09640	COG0589	response to stress
BsBEST3095_09660	COG1132	(ABC) transporter
BsBEST3095_09670	COG1132	(ABC) transporter
BsBEST3095_09680	COG0702	epimerase
BsBEST3095_09710	COG0189	ligase activity
BsBEST3095_09720	COG0189	ligase activity
BsBEST3095_09730	COG4399	Belongs to the UPF0754 family
BsBEST3095_09740	COG3679	Belongs to the UPF0342 family
BsBEST3095_09750	COG4335	DNA alkylation repair
BsBEST3095_09760	COG0561	phosphatase activity
BsBEST3095_09770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3095_09780	COG0475	glutathione-regulated potassium exporter activity
BsBEST3095_09790	COG0490	domain, Protein
BsBEST3095_09810	COG1024	Enoyl-CoA hydratase
BsBEST3095_09830	COG4152	abc transporter atp-binding protein
BsBEST3095_09840	COG1668	transmembrane transport
BsBEST3095_09850	COG0420	3'-5' exonuclease activity
BsBEST3095_09860	COG4717	serine-type aminopeptidase activity
BsBEST3095_09870	COG3481	metal-dependent phosphohydrolase, HD sub domain
BsBEST3095_09890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3095_09920	COG1846	Transcriptional regulator
BsBEST3095_09930	COG4980	gas vesicle protein
BsBEST3095_09950	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BsBEST3095_09960	COG0537	adenosine 5'-monophosphoramidase activity
BsBEST3095_09970	COG1131	(ABC) transporter
BsBEST3095_09980	COG4473	ABC transporter
BsBEST3095_10000	COG1473	amidohydrolase
BsBEST3095_10010	COG1473	amidohydrolase
BsBEST3095_10020	COG3069	C4-dicarboxylate transmembrane transporter activity
BsBEST3095_10030	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3095_10040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3095_10050	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BsBEST3095_10060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BsBEST3095_10070	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BsBEST3095_10080	COG1309	transcriptional regulator
BsBEST3095_10090	COG1511	domain protein
BsBEST3095_10100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3095_10110	COG4377	Putative membrane peptidase family (DUF2324)
BsBEST3095_10130	COG1363	Peptidase, m42
BsBEST3095_10140	COG4405	Protein conserved in bacteria
BsBEST3095_10150	COG1301	dicarboxylic acid transport
BsBEST3095_10160	COG1234	tRNA 3'-trailer cleavage
BsBEST3095_10170	COG0095	Lipoate-protein ligase
BsBEST3095_10180	COG0702	epimerase
BsBEST3095_10190	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3095_10210	COG0501	Belongs to the peptidase M48B family
BsBEST3095_10220	COG1404	Belongs to the peptidase S8 family
BsBEST3095_10230	COG0456	acetyltransferase
BsBEST3095_10240	COG0604	alcohol dehydrogenase
BsBEST3095_10250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3095_10260	COG0406	alpha-ribazole phosphatase activity
BsBEST3095_10270	COG0183	Belongs to the thiolase family
BsBEST3095_10280	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3095_10290	COG1268	BioY protein
BsBEST3095_10300	COG0840	transmembrane signaling receptor activity
BsBEST3095_10310	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3095_10310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3095_10320	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_10340	COG4903	ComK protein
BsBEST3095_10350	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_10370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3095_10400	COG0398	Pfam SNARE associated Golgi protein
BsBEST3095_10410	COG0681	Belongs to the peptidase S26 family
BsBEST3095_10420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3095_10430	COG1846	Transcriptional regulator
BsBEST3095_10440	COG0738	Major facilitator superfamily
BsBEST3095_10460	COG0673	inositol 2-dehydrogenase activity
BsBEST3095_10470	COG0561	phosphatase activity
BsBEST3095_10480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3095_10490	COG1609	Transcriptional regulator
BsBEST3095_10500	COG3180	Ammonia monooxygenase
BsBEST3095_10510	COG2814	Major facilitator Superfamily
BsBEST3095_10510	COG0477	Major facilitator Superfamily
BsBEST3095_10520	COG4533	DNA binding
BsBEST3095_10540	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BsBEST3095_10550	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BsBEST3095_10560	COG1074	ATP-dependent DNA helicase activity
BsBEST3095_10570	COG0420	3'-5' exonuclease activity
BsBEST3095_10580	COG0419	ATPase involved in DNA repair
BsBEST3095_10590	COG1403	HNH endonuclease
BsBEST3095_10670	COG0179	Fumarylacetoacetate (FAA) hydrolase
BsBEST3095_10690	COG1404	Belongs to the peptidase S8 family
BsBEST3095_10710	COG0367	asparagine synthase
BsBEST3095_10720	COG2318	DinB family
BsBEST3095_10730	COG1562	ergosterol biosynthetic process
BsBEST3095_10740	COG0534	Mate efflux family protein
BsBEST3095_10750	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3095_10750	COG2207	Transcriptional regulator
BsBEST3095_10760	COG1609	Transcriptional regulator
BsBEST3095_10770	COG0673	inositol 2-dehydrogenase activity
BsBEST3095_10780	COG2318	DinB family
BsBEST3095_10790	COG1279	arginine transmembrane transporter activity
BsBEST3095_10800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3095_10810	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3095_10820	COG2267	carboxylic ester hydrolase activity
BsBEST3095_10830	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3095_10840	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3095_10850	COG0175	sulfate reduction
BsBEST3095_10860	COG2045	Belongs to the ComB family
BsBEST3095_10870	COG1809	phosphosulfolactate synthase activity
BsBEST3095_10880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3095_10890	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3095_10900	COG2814	Major facilitator Superfamily
BsBEST3095_10910	COG0454	-acetyltransferase
BsBEST3095_10920	COG2153	protein acetylation
BsBEST3095_10930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BsBEST3095_10930	COG0646	methionine synthase
BsBEST3095_10940	COG1666	GTP binding
BsBEST3095_10950	COG2996	Protein conserved in bacteria
BsBEST3095_10990	COG1695	Transcriptional regulator
BsBEST3095_11020	COG3227	Zinc metalloprotease (Elastase)
BsBEST3095_11030	COG1307	EDD domain protein, DegV family
BsBEST3095_11040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3095_11070	COG0561	phosphatase activity
BsBEST3095_11080	COG1073	alpha beta
BsBEST3095_11090	COG2151	metal-sulfur cluster biosynthetic enzyme
BsBEST3095_11110	COG0277	FAD linked oxidase domain protein
BsBEST3095_11120	COG2271	Major facilitator Superfamily
BsBEST3095_11130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BsBEST3095_11140	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BsBEST3095_11160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3095_11170	COG0505	Belongs to the CarA family
BsBEST3095_11180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3095_11190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BsBEST3095_11220	COG2267	carboxylic ester hydrolase activity
BsBEST3095_11240	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3095_11270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3095_11280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3095_11290	COG5504	Zn-dependent protease
BsBEST3095_11300	COG0444	Belongs to the ABC transporter superfamily
BsBEST3095_11310	COG4608	Belongs to the ABC transporter superfamily
BsBEST3095_11340	COG0601	transmembrane transport
BsBEST3095_11350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3095_11370	COG0180	Tryptophanyl-tRNA synthetase
BsBEST3095_11380	COG4166	transmembrane transport
BsBEST3095_11390	COG0601	transmembrane transport
BsBEST3095_11400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3095_11410	COG0444	Belongs to the ABC transporter superfamily
BsBEST3095_11420	COG4608	Belongs to the ABC transporter superfamily
BsBEST3095_11430	COG2814	Major facilitator Superfamily
BsBEST3095_11440	COG0456	acetyltransferase
BsBEST3095_11450	COG1393	Belongs to the ArsC family
BsBEST3095_11460	COG0861	Integral membrane protein TerC family
BsBEST3095_11470	COG4862	establishment of competence for transformation
BsBEST3095_11480	COG1164	Oligoendopeptidase f
BsBEST3095_11500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3095_11510	COG2346	COG2346, Truncated hemoglobins
BsBEST3095_11520	COG0741	lytic transglycosylase activity
BsBEST3095_11530	COG4116	CYTH
BsBEST3095_11550	COG2357	RelA SpoT domain protein
BsBEST3095_11560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3095_11570	COG0564	pseudouridine synthase activity
BsBEST3095_11580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BsBEST3095_11590	COG0475	glutathione-regulated potassium exporter activity
BsBEST3095_11590	COG0569	domain protein
BsBEST3095_11600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BsBEST3095_11610	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3095_11620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3095_11630	COG2104	thiamine diphosphate biosynthetic process
BsBEST3095_11640	COG2022	thiamine diphosphate biosynthetic process
BsBEST3095_11650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3095_11660	COG0351	phosphomethylpyrimidine kinase
BsBEST3095_11670	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BsBEST3095_11780	COG0210	DNA helicase
BsBEST3095_11800	COG2153	protein acetylation
BsBEST3095_11810	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3095_11820	COG2382	esterase
BsBEST3095_11830	COG0626	cystathionine gamma-synthase activity
BsBEST3095_11840	COG0626	cystathionine gamma-synthase activity
BsBEST3095_11850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3095_11860	COG5505	Protein of unknown function (DUF819)
BsBEST3095_11920	COG3677	Transposase
BsBEST3095_11950	COG5484	DNA packaging
BsBEST3095_11960	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3095_11970	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_11990	COG3711	transcriptional antiterminator
BsBEST3095_11990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3095_12000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3095_12000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3095_12000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3095_12010	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3095_12030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3095_12050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3095_12090	COG0109	protoheme IX farnesyltransferase activity
BsBEST3095_12110	COG0726	polysaccharide deacetylase
BsBEST3095_12140	COG5504	Zn-dependent protease
BsBEST3095_12150	COG2205	protein histidine kinase activity
BsBEST3095_12170	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3095_12180	COG2427	Protein of unknown function (DUF1641)
BsBEST3095_12200	COG1051	belongs to the nudix hydrolase family
BsBEST3095_12220	COG2124	cytochrome p450
BsBEST3095_12230	COG1819	glycosyl
BsBEST3095_12250	COG1587	Uroporphyrinogen-III synthase
BsBEST3095_12260	COG0390	transport system, permease component
BsBEST3095_12270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3095_12280	COG0697	spore germination
BsBEST3095_12290	COG4297	protein containing double-stranded beta helix domain
BsBEST3095_12310	COG1252	NADH dehydrogenase
BsBEST3095_12320	COG1904	glucuronate isomerase
BsBEST3095_12330	COG2211	Major facilitator Superfamily
BsBEST3095_12340	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BsBEST3095_12350	COG1063	alcohol dehydrogenase
BsBEST3095_12360	COG1312	Catalyzes the dehydration of D-mannonate
BsBEST3095_12370	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_12380	COG2271	Major facilitator Superfamily
BsBEST3095_12390	COG1609	Transcriptional regulator
BsBEST3095_12400	COG0246	Mannitol dehydrogenase
BsBEST3095_12410	COG2721	sulfolactate sulfo-lyase activity
BsBEST3095_12420	COG0730	response to heat
BsBEST3095_12430	COG2318	DinB family
BsBEST3095_12440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3095_12450	COG0457	Tetratricopeptide repeat
BsBEST3095_12470	COG2350	Protein conserved in bacteria
BsBEST3095_12480	COG1388	LysM domain
BsBEST3095_12480	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_12480	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_12500	COG4195	phage-related replication protein
BsBEST3095_12510	COG3546	catalase activity
BsBEST3095_12520	COG2856	Zn peptidase
BsBEST3095_12530	COG1396	sequence-specific DNA binding
BsBEST3095_12550	COG1522	sequence-specific DNA binding
BsBEST3095_12560	COG1484	DNA-dependent DNA replication
BsBEST3095_12600	COG1595	DNA-templated transcription, initiation
BsBEST3095_12610	COG5484	DNA packaging
BsBEST3095_12610	COG3728	DNA packaging
BsBEST3095_12620	COG1783	phage Terminase large subunit
BsBEST3095_12630	COG5518	Phage portal protein
BsBEST3095_12640	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3095_12650	COG4653	Phage capsid family
BsBEST3095_12750	COG5412	phage tail tape measure protein
BsBEST3095_12750	COG3953	SLT domain
BsBEST3095_12760	COG1652	LysM domain
BsBEST3095_12770	COG4193	domain, Protein
BsBEST3095_12790	COG3628	GPW Gp25 family protein
BsBEST3095_12800	COG3299	homolog of phage Mu protein gp47
BsBEST3095_12810	COG3778	Protein conserved in bacteria
BsBEST3095_12890	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_12890	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_12920	COG0306	phosphate transporter
BsBEST3095_12930	COG1392	Phosphate transport regulator
BsBEST3095_12940	COG0531	amino acid
BsBEST3095_12950	COG0346	lactoylglutathione lyase activity
BsBEST3095_12970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3095_12980	COG0463	Glycosyl transferase, family 2
BsBEST3095_13000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3095_13010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3095_13020	COG2362	D-Aminopeptidase
BsBEST3095_13030	COG0601	transmembrane transport
BsBEST3095_13040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3095_13050	COG0444	Belongs to the ABC transporter superfamily
BsBEST3095_13060	COG4166	transmembrane transport
BsBEST3095_13070	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3095_13080	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3095_13090	COG0791	NLP P60 protein
BsBEST3095_13100	COG4608	Belongs to the ABC transporter superfamily
BsBEST3095_13110	COG2706	6-phosphogluconolactonase activity
BsBEST3095_13120	COG1834	amidinotransferase
BsBEST3095_13130	COG1607	acyl-coa hydrolase
BsBEST3095_13140	COG1017	nitric oxide dioxygenase activity
BsBEST3095_13140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BsBEST3095_13160	COG2323	membrane
BsBEST3095_13170	COG2318	DinB family
BsBEST3095_13180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3095_13190	COG2076	Multidrug Resistance protein
BsBEST3095_13200	COG2076	Multidrug Resistance protein
BsBEST3095_13210	COG0788	formyltetrahydrofolate deformylase activity
BsBEST3095_13220	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3095_13230	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BsBEST3095_13240	COG1764	response to oxidative stress
BsBEST3095_13250	COG1846	Transcriptional regulator
BsBEST3095_13260	COG1764	response to oxidative stress
BsBEST3095_13280	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3095_13290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3095_13300	COG1404	Belongs to the peptidase S8 family
BsBEST3095_13310	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3095_13320	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3095_13330	COG1122	ATPase activity
BsBEST3095_13340	COG4721	ABC-type cobalt transport system, permease component
BsBEST3095_13360	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_13370	COG5002	protein histidine kinase activity
BsBEST3095_13370	COG3850	Histidine kinase
BsBEST3095_13380	COG3212	peptidase
BsBEST3095_13390	COG3212	peptidase
BsBEST3095_13410	COG2239	Acts as a magnesium transporter
BsBEST3095_13420	COG0789	Transcriptional regulator
BsBEST3095_13450	COG1846	Transcriptional regulator
BsBEST3095_13460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3095_13470	COG0726	polysaccharide deacetylase
BsBEST3095_13480	COG1408	metallophosphoesterase
BsBEST3095_13500	COG0463	Glycosyl transferase, family 2
BsBEST3095_13510	COG1793	dna ligase
BsBEST3095_13510	COG3285	dna ligase
BsBEST3095_13520	COG3285	dna ligase
BsBEST3095_13520	COG1793	dna ligase
BsBEST3095_13530	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BsBEST3095_13540	COG3300	MHYT domain
BsBEST3095_13540	COG5001	Diguanylate cyclase
BsBEST3095_13550	COG0586	Pfam SNARE associated Golgi protein
BsBEST3095_13560	COG0861	Integral membrane protein TerC family
BsBEST3095_13570	COG1191	sigma factor activity
BsBEST3095_13610	COG0501	Belongs to the peptidase M48B family
BsBEST3095_13620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3095_13650	COG3594	Acyltransferase
BsBEST3095_13660	COG5002	protein histidine kinase activity
BsBEST3095_13670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3095_13690	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BsBEST3095_13700	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BsBEST3095_13710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3095_13720	COG0436	Aminotransferase
BsBEST3095_13730	COG1850	ribulose-bisphosphate carboxylase activity
BsBEST3095_13740	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BsBEST3095_13750	COG0235	Class ii aldolase
BsBEST3095_13760	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BsBEST3095_13770	COG3339	Conserved Protein
BsBEST3095_13800	COG3852	Histidine kinase
BsBEST3095_13810	COG1846	Transcriptional regulator
BsBEST3095_13820	COG1360	Flagellar Motor Protein
BsBEST3095_13830	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3095_13840	COG0542	response to heat
BsBEST3095_13850	COG3949	Membrane
BsBEST3095_13860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BsBEST3095_13870	COG0720	synthase
BsBEST3095_13880	COG0602	queuosine metabolic process
BsBEST3095_13890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BsBEST3095_13900	COG1733	regulation of RNA biosynthetic process
BsBEST3095_13910	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_13920	COG1388	LysM domain
BsBEST3095_13920	COG4641	Protein conserved in bacteria
BsBEST3095_13930	COG1388	LysM domain
BsBEST3095_13940	COG3858	chitin binding
BsBEST3095_13950	COG3858	chitin binding
BsBEST3095_13970	COG4873	Protein conserved in bacteria
BsBEST3095_13990	COG3773	Cell wall hydrolase
BsBEST3095_14000	COG2244	polysaccharide biosynthetic process
BsBEST3095_14010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_14020	COG2217	Heavy metal translocating P-type atpase
BsBEST3095_14040	COG0006	proline dipeptidase activity
BsBEST3095_14060	COG1609	Transcriptional regulator
BsBEST3095_14070	COG3711	transcriptional antiterminator
BsBEST3095_14080	COG1263	PTS System
BsBEST3095_14080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3095_14080	COG2190	(PTS) system
BsBEST3095_14090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3095_14100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BsBEST3095_14120	COG1533	DNA photolyase activity
BsBEST3095_14130	COG0456	acetyltransferase
BsBEST3095_14140	COG0840	transmembrane signaling receptor activity
BsBEST3095_14150	COG2084	Dehydrogenase
BsBEST3095_14160	COG2340	Cysteine-rich secretory protein family
BsBEST3095_14170	COG0768	penicillin binding
BsBEST3095_14180	COG4191	Histidine kinase
BsBEST3095_14190	COG0436	Aminotransferase
BsBEST3095_14210	COG0784	Response regulator, receiver
BsBEST3095_14210	COG0835	chemotaxis
BsBEST3095_14230	COG2814	Major facilitator Superfamily
BsBEST3095_14240	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3095_14250	COG1408	metallophosphoesterase
BsBEST3095_14260	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_14270	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_14280	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_14300	COG2200	EAL domain
BsBEST3095_14310	COG4703	Protein of unknown function (DUF1797)
BsBEST3095_14320	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BsBEST3095_14340	COG0517	IMP dehydrogenase activity
BsBEST3095_14350	COG0583	DNA-binding transcription factor activity
BsBEST3095_14360	COG0716	FMN binding
BsBEST3095_14380	COG0716	FMN binding
BsBEST3095_14390	COG2171	N-acyltransferase activity
BsBEST3095_14400	COG1473	amidohydrolase
BsBEST3095_14420	COG0668	transmembrane transport
BsBEST3095_14430	COG0450	alkyl hydroperoxide reductase
BsBEST3095_14440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_14470	COG0746	molybdenum cofactor guanylyltransferase activity
BsBEST3095_14480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3095_14490	COG0303	'Molybdopterin
BsBEST3095_14500	COG1763	Mo-molybdopterin cofactor biosynthetic process
BsBEST3095_14510	COG0314	molybdopterin synthase activity
BsBEST3095_14520	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BsBEST3095_14530	COG1132	(ABC) transporter
BsBEST3095_14540	COG1132	(ABC) transporter
BsBEST3095_14560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3095_14570	COG1136	(ABC) transporter
BsBEST3095_14580	COG0577	efflux transmembrane transporter activity
BsBEST3095_14590	COG1349	DNA-binding transcription factor activity
BsBEST3095_14600	COG1105	Belongs to the carbohydrate kinase PfkB family
BsBEST3095_14610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3095_14610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3095_14610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3095_14620	COG0681	Belongs to the peptidase S26 family
BsBEST3095_14640	COG0488	(ABC) transporter
BsBEST3095_14650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3095_14660	COG2309	aminopeptidase activity
BsBEST3095_14680	COG1077	Cell shape determining protein MreB Mrl
BsBEST3095_14690	COG2002	toxin-antitoxin pair type II binding
BsBEST3095_14700	COG3852	Histidine kinase
BsBEST3095_14710	COG2105	PFAM AIG2 family protein
BsBEST3095_14710	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BsBEST3095_14720	COG0569	domain protein
BsBEST3095_14730	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3095_14740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3095_14750	COG5503	Protein of unknown function (DUF1447)
BsBEST3095_14760	COG0561	phosphatase activity
BsBEST3095_14770	COG0242	peptide deformylase activity
BsBEST3095_14790	COG0497	DNA recombination
BsBEST3095_14800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3095_14810	COG0022	dehydrogenase e1 component
BsBEST3095_14820	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3095_14830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3095_14840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_14850	COG1982	Orn Lys Arg decarboxylase major
BsBEST3095_14860	COG4476	Belongs to the UPF0223 family
BsBEST3095_14870	COG4493	Belongs to the UPF0637 family
BsBEST3095_14890	COG0483	inositol monophosphate 1-phosphatase activity
BsBEST3095_14910	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BsBEST3095_14950	COG1595	DNA-templated transcription, initiation
BsBEST3095_14990	COG1217	gtp-binding protein TYPA
BsBEST3095_15010	COG4896	Protein conserved in bacteria
BsBEST3095_15030	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BsBEST3095_15040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3095_15050	COG2066	Belongs to the glutaminase family
BsBEST3095_15060	COG4838	Belongs to the UPF0358 family
BsBEST3095_15080	COG0772	Belongs to the SEDS family
BsBEST3095_15090	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BsBEST3095_15100	COG1612	heme a metabolic process
BsBEST3095_15110	COG0109	protoheme IX farnesyltransferase activity
BsBEST3095_15120	COG2010	Cytochrome c
BsBEST3095_15120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3095_15130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3095_15140	COG1845	cytochrome c oxidase, subunit III
BsBEST3095_15150	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3095_15160	COG3336	cytochrome c oxidase
BsBEST3095_15180	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BsBEST3095_15190	COG2340	Cysteine-rich secretory protein family
BsBEST3095_15220	COG3679	Belongs to the UPF0342 family
BsBEST3095_15230	COG4471	UPF0298 protein
BsBEST3095_15240	COG0742	ribosomal rna small subunit methyltransferase
BsBEST3095_15250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BsBEST3095_15260	COG3314	Sporulation integral membrane protein YlbJ
BsBEST3095_15270	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3095_15280	COG3480	Lon protease (S16) C-terminal proteolytic domain
BsBEST3095_15290	COG1323	Belongs to the UPF0348 family
BsBEST3095_15300	COG1399	metal-binding, possibly nucleic acid-binding protein
BsBEST3095_15330	COG0454	-acetyltransferase
BsBEST3095_15340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3095_15350	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BsBEST3095_15360	COG2001	Belongs to the MraZ family
BsBEST3095_15370	COG0275	rRNA processing
BsBEST3095_15380	COG4839	cell division protein FtsL
BsBEST3095_15390	COG0768	penicillin binding
BsBEST3095_15400	COG0768	penicillin binding
BsBEST3095_15410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BsBEST3095_15420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3095_15430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3095_15440	COG0772	Belongs to the SEDS family
BsBEST3095_15450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3095_15460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BsBEST3095_15470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BsBEST3095_15480	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3095_15490	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3095_15500	COG3856	small basic protein
BsBEST3095_15510	COG0849	cell division
BsBEST3095_15520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BsBEST3095_15530	COG1404	Belongs to the peptidase S8 family
BsBEST3095_15530	COG4412	M6 family metalloprotease domain protein
BsBEST3095_15550	COG1191	sigma factor activity
BsBEST3095_15560	COG1191	sigma factor activity
BsBEST3095_15570	COG1119	ATPase activity
BsBEST3095_15580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3095_15590	COG1873	PFAM PRC-barrel domain
BsBEST3095_15600	COG1496	oxidoreductase activity
BsBEST3095_15610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BsBEST3095_15620	COG1799	cell septum assembly
BsBEST3095_15630	COG0762	integral membrane protein
BsBEST3095_15640	COG2302	S4 RNA-binding domain
BsBEST3095_15650	COG3599	regulation of cell shape
BsBEST3095_15660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BsBEST3095_15670	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3095_15680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BsBEST3095_15690	COG0564	pseudouridine synthase activity
BsBEST3095_15700	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BsBEST3095_15710	COG2233	PERMEase
BsBEST3095_15720	COG0540	Belongs to the ATCase OTCase family
BsBEST3095_15730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3095_15740	COG0505	Belongs to the CarA family
BsBEST3095_15750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3095_15760	COG0543	2 iron, 2 sulfur cluster binding
BsBEST3095_15770	COG0167	dihydroorotate dehydrogenase activity
BsBEST3095_15780	COG0284	orotidine-5'-phosphate decarboxylase activity
BsBEST3095_15790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BsBEST3095_15800	COG0175	sulfate reduction
BsBEST3095_15810	COG0306	phosphate transporter
BsBEST3095_15820	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3095_15830	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3095_15840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3095_15850	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BsBEST3095_15860	COG1648	precorrin-2 dehydrogenase activity
BsBEST3095_15870	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BsBEST3095_15880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3095_15890	COG1561	YicC-like family, N-terminal region
BsBEST3095_15910	COG0194	GDP metabolic process
BsBEST3095_15920	COG1758	RNA polymerase activity
BsBEST3095_15930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3095_15940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3095_15950	COG0242	peptide deformylase activity
BsBEST3095_15960	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BsBEST3095_15970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BsBEST3095_15970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3095_15980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BsBEST3095_15990	COG0631	protein serine/threonine phosphatase activity
BsBEST3095_16000	COG2815	serine threonine protein kinase
BsBEST3095_16000	COG0515	serine threonine protein kinase
BsBEST3095_16010	COG1162	GTPase activity
BsBEST3095_16020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BsBEST3095_16030	COG1564	THIamine pyrophosphokinase
BsBEST3095_16040	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BsBEST3095_16050	COG1302	Protein conserved in bacteria
BsBEST3095_16060	COG1461	Dihydroxyacetone kinase
BsBEST3095_16070	COG1760	l-serine dehydratase
BsBEST3095_16080	COG1760	l-serine dehydratase
BsBEST3095_16090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BsBEST3095_16100	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3095_16100	COG1349	DNA-binding transcription factor activity
BsBEST3095_16110	COG0416	fatty acid biosynthetic process
BsBEST3095_16120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3095_16130	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_16150	COG0571	ribonuclease III activity
BsBEST3095_16160	COG1196	nuclear chromosome segregation
BsBEST3095_16170	COG0552	protein localization to endoplasmic reticulum
BsBEST3095_16190	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BsBEST3095_16200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BsBEST3095_16210	COG0228	four-way junction DNA binding
BsBEST3095_16220	COG1837	Belongs to the UPF0109 family
BsBEST3095_16240	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BsBEST3095_16250	COG0336	Belongs to the RNA methyltransferase TrmD family
BsBEST3095_16260	COG0335	large ribosomal subunit rRNA binding
BsBEST3095_16270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3095_16280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3095_16300	COG2257	FlhB HrpN YscU SpaS Family
BsBEST3095_16310	COG0045	succinate-CoA ligase (ADP-forming) activity
BsBEST3095_16320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BsBEST3095_16330	COG0758	DNA mediated transformation
BsBEST3095_16340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3095_16350	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BsBEST3095_16360	COG4974	Belongs to the 'phage' integrase family
BsBEST3095_16370	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BsBEST3095_16380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BsBEST3095_16390	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3095_16400	COG1815	bacterial-type flagellum-dependent cell motility
BsBEST3095_16410	COG1558	bacterial-type flagellum-dependent cell motility
BsBEST3095_16420	COG1677	Flagellar hook-basal body complex protein FliE
BsBEST3095_16430	COG1766	The M ring may be actively involved in energy transduction
BsBEST3095_16440	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3095_16450	COG1317	bacterial-type flagellum organization
BsBEST3095_16460	COG1157	protein secretion by the type III secretion system
BsBEST3095_16470	COG2882	bacterial-type flagellum organization
BsBEST3095_16480	COG3334	PFAM MgtE intracellular
BsBEST3095_16490	COG3144	bacterial-type flagellum assembly
BsBEST3095_16500	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BsBEST3095_16510	COG4786	Flagellar basal body rod
BsBEST3095_16520	COG1582	Flagellar protein (FlbD)
BsBEST3095_16530	COG1580	Controls the rotational direction of flagella during chemotaxis
BsBEST3095_16540	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3095_16550	COG1776	CheC inhibitor of MCP methylation
BsBEST3095_16550	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3095_16560	COG2201	protein-glutamate methylesterase activity
BsBEST3095_16570	COG3190	flagellar
BsBEST3095_16580	COG1338	Plays a role in the flagellum-specific transport system
BsBEST3095_16590	COG1987	bacterial-type flagellum assembly
BsBEST3095_16600	COG1684	flagellar biosynthetic protein fliR
BsBEST3095_16610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3095_16620	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3095_16630	COG1419	protein localization to endoplasmic reticulum
BsBEST3095_16640	COG0455	bacterial-type flagellum organization
BsBEST3095_16650	COG2201	protein-glutamate methylesterase activity
BsBEST3095_16660	COG2198	Histidine kinase
BsBEST3095_16660	COG0643	Histidine kinase
BsBEST3095_16670	COG0835	chemotaxis
BsBEST3095_16680	COG1776	CheC inhibitor of MCP methylation
BsBEST3095_16690	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BsBEST3095_16700	COG1191	sigma factor activity
BsBEST3095_16720	COG0052	Belongs to the universal ribosomal protein uS2 family
BsBEST3095_16730	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BsBEST3095_16740	COG0528	UMP kinase activity
BsBEST3095_16750	COG0233	cytoplasmic translational termination
BsBEST3095_16760	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BsBEST3095_16770	COG4589	Belongs to the CDS family
BsBEST3095_16780	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BsBEST3095_16790	COG0750	zinc metalloprotease
BsBEST3095_16800	COG0442	prolyl-tRNA aminoacylation
BsBEST3095_16810	COG2176	DNA-directed DNA polymerase activity
BsBEST3095_16820	COG0779	Required for maturation of 30S ribosomal subunits
BsBEST3095_16830	COG0195	Participates in both transcription termination and antitermination
BsBEST3095_16840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BsBEST3095_16850	COG1358	cellular component organization or biogenesis
BsBEST3095_16860	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BsBEST3095_16870	COG1550	Protein conserved in bacteria
BsBEST3095_16880	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BsBEST3095_16890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BsBEST3095_16900	COG0196	riboflavin kinase activity
BsBEST3095_16910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BsBEST3095_16920	COG1185	polyribonucleotide nucleotidyltransferase activity
BsBEST3095_16930	COG0726	polysaccharide deacetylase
BsBEST3095_16940	COG0612	Peptidase, M16
BsBEST3095_16950	COG1873	PFAM PRC-barrel domain
BsBEST3095_16960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3095_16970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3095_16980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BsBEST3095_16990	COG0527	aspartate kinase activity
BsBEST3095_17000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3095_17010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3095_17020	COG0740	serine-type endopeptidase activity
BsBEST3095_17040	COG1674	ftsk spoiiie
BsBEST3095_17040	COG4980	gas vesicle protein
BsBEST3095_17050	COG2188	Transcriptional regulator
BsBEST3095_17060	COG2814	Major facilitator Superfamily
BsBEST3095_17070	COG0612	Peptidase, M16
BsBEST3095_17080	COG0612	Peptidase, M16
BsBEST3095_17090	COG0300	oxidoreductase activity
BsBEST3095_17130	COG1426	Protein conserved in bacteria
BsBEST3095_17140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BsBEST3095_17150	COG1058	Belongs to the CinA family
BsBEST3095_17150	COG1546	Belongs to the CinA family
BsBEST3095_17160	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BsBEST3095_17170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3095_17180	COG1418	mRNA catabolic process
BsBEST3095_17190	COG1692	metallophosphoesterase
BsBEST3095_17200	COG2359	stage V sporulation protein S
BsBEST3095_17210	COG1063	alcohol dehydrogenase
BsBEST3095_17220	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3095_17230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3095_17240	COG4550	Control of competence regulator ComK, YlbF/YmcA
BsBEST3095_17260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BsBEST3095_17270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BsBEST3095_17300	COG3226	Transcriptional regulator
BsBEST3095_17310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3095_17330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3095_17340	COG3321	synthase
BsBEST3095_17350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3095_17350	COG2070	2-Nitropropane dioxygenase
BsBEST3095_17360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3095_17370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3095_17380	COG3425	synthase
BsBEST3095_17390	COG1024	Enoyl-CoA hydratase
BsBEST3095_17400	COG1024	Enoyl-CoA hydratase
BsBEST3095_17410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_17410	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3095_17410	COG3321	synthase
BsBEST3095_17410	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_17410	COG0300	oxidoreductase activity
BsBEST3095_17420	COG0300	oxidoreductase activity
BsBEST3095_17420	COG4221	oxidoreductase activity
BsBEST3095_17420	COG3321	synthase
BsBEST3095_17420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3095_17430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3095_17430	COG3321	synthase
BsBEST3095_17430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_17430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3095_17430	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_17440	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_17440	COG4221	oxidoreductase activity
BsBEST3095_17440	COG3321	synthase
BsBEST3095_17440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_17450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_17450	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_17450	COG3321	synthase
BsBEST3095_17450	COG4221	oxidoreductase activity
BsBEST3095_17460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3095_17460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BsBEST3095_17460	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3095_17460	COG3321	synthase
BsBEST3095_17470	COG2124	cytochrome p450
BsBEST3095_17490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3095_17500	COG1404	Belongs to the peptidase S8 family
BsBEST3095_17510	COG4195	phage-related replication protein
BsBEST3095_17520	COG1764	response to oxidative stress
BsBEST3095_17530	COG2076	Multidrug Resistance protein
BsBEST3095_17540	COG2076	Multidrug Resistance protein
BsBEST3095_17570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BsBEST3095_17580	COG1923	regulation of RNA biosynthetic process
BsBEST3095_17610	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3095_17620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3095_17630	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3095_17640	COG4112	unkown
BsBEST3095_17650	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_17660	COG0464	growth
BsBEST3095_17670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BsBEST3095_17680	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BsBEST3095_17690	COG0789	Transcriptional regulator
BsBEST3095_17700	COG0174	glutamine synthetase
BsBEST3095_17740	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3095_17760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3095_17810	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3095_17820	COG2211	Major facilitator Superfamily
BsBEST3095_17830	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3095_17840	COG1940	carbohydrate kinase activity
BsBEST3095_17850	COG2115	Belongs to the xylose isomerase family
BsBEST3095_17860	COG1070	Carbohydrate kinase
BsBEST3095_17870	COG1525	nuclease
BsBEST3095_17880	COG2814	Major facilitator Superfamily
BsBEST3095_17890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3095_17910	COG0756	dUTP diphosphatase activity
BsBEST3095_17960	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3095_18010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3095_18030	COG3832	glyoxalase III activity
BsBEST3095_18050	COG0697	spore germination
BsBEST3095_18060	COG0531	amino acid
BsBEST3095_18120	COG4195	phage-related replication protein
BsBEST3095_18140	COG0346	lactoylglutathione lyase activity
BsBEST3095_18150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BsBEST3095_18160	COG1388	LysM domain
BsBEST3095_18170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3095_18180	COG4224	UPF0291 protein
BsBEST3095_18190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BsBEST3095_18210	COG3763	UPF0154 protein
BsBEST3095_18230	COG0785	Cytochrome C biogenesis protein
BsBEST3095_18240	COG2201	protein-glutamate methylesterase activity
BsBEST3095_18250	COG4846	Membrane protein involved in cytochrome C biogenesis
BsBEST3095_18270	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3095_18300	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BsBEST3095_18310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_18350	COG0824	Thioesterase
BsBEST3095_18370	COG4841	protein insertion into membrane
BsBEST3095_18380	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BsBEST3095_18390	COG1832	CoA-binding protein
BsBEST3095_18400	COG0187	DNA topoisomerase II activity
BsBEST3095_18410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3095_18430	COG1115	amino acid carrier protein
BsBEST3095_18440	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BsBEST3095_18460	COG5520	Belongs to the glycosyl hydrolase 30 family
BsBEST3095_18470	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3095_18480	COG2246	polysaccharide biosynthetic process
BsBEST3095_18490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3095_18500	COG0586	Pfam SNARE associated Golgi protein
BsBEST3095_18510	COG2404	hydrolase activity, acting on ester bonds
BsBEST3095_18520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3095_18530	COG1024	Enoyl-CoA hydratase
BsBEST3095_18540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3095_18550	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3095_18560	COG0439	Biotin carboxylase
BsBEST3095_18570	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3095_18580	COG1960	acyl-CoA dehydrogenase activity
BsBEST3095_18600	COG1649	PFAM Uncharacterised BCR, COG1649
BsBEST3095_18620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_18620	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3095_18630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_18640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_18650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_18660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_18670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_18680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_18690	COG2027	D-alanyl-D-alanine carboxypeptidase
BsBEST3095_18700	COG2017	converts alpha-aldose to the beta-anomer
BsBEST3095_18710	COG0534	Mate efflux family protein
BsBEST3095_18730	COG0582	viral genome integration into host DNA
BsBEST3095_18740	COG0166	Belongs to the GPI family
BsBEST3095_18750	COG0405	Gamma-glutamyltransferase
BsBEST3095_18760	COG0583	DNA-binding transcription factor activity
BsBEST3095_18770	COG0604	alcohol dehydrogenase
BsBEST3095_18780	COG0493	'glutamate synthase
BsBEST3095_18790	COG0067	glutamate synthase
BsBEST3095_18790	COG0070	glutamate synthase
BsBEST3095_18790	COG0069	glutamate synthase activity
BsBEST3095_18800	COG0583	DNA-binding transcription factor activity
BsBEST3095_18810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3095_18820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3095_18840	COG0300	oxidoreductase activity
BsBEST3095_18850	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3095_18870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3095_18880	COG2814	Major facilitator Superfamily
BsBEST3095_18890	COG1070	Carbohydrate kinase
BsBEST3095_18900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3095_18910	COG0243	molybdopterin cofactor binding
BsBEST3095_18960	COG0840	transmembrane signaling receptor activity
BsBEST3095_18960	COG5278	phosphoserine phosphatase activity
BsBEST3095_18970	COG2368	4-hydroxyphenylacetate
BsBEST3095_18980	COG4305	rare lipoprotein A
BsBEST3095_18990	COG3619	membrane
BsBEST3095_19000	COG3866	Pectate lyase
BsBEST3095_19010	COG2135	peptidase activity
BsBEST3095_19030	COG2140	Oxalate decarboxylase
BsBEST3095_19050	COG0456	acetyltransferase
BsBEST3095_19080	COG2720	vancomycin resistance protein
BsBEST3095_19100	COG3655	Transcriptional regulator
BsBEST3095_19110	COG3739	integral membrane protein
BsBEST3095_19120	COG0583	DNA-binding transcription factor activity
BsBEST3095_19130	COG0697	spore germination
BsBEST3095_19150	COG0693	protein deglycase activity
BsBEST3095_19160	COG2367	Beta-lactamase
BsBEST3095_19200	COG3848	Pyruvate phosphate dikinase
BsBEST3095_19200	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3095_19210	COG0726	polysaccharide deacetylase
BsBEST3095_19220	COG2314	TM2 domain
BsBEST3095_19230	COG1396	sequence-specific DNA binding
BsBEST3095_19260	COG2135	peptidase activity
BsBEST3095_19320	COG0457	Tetratricopeptide repeat
BsBEST3095_19340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3095_19350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3095_19380	COG5290	Psort location Cytoplasmic, score
BsBEST3095_19420	COG5444	nuclease activity
BsBEST3095_19430	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3095_19440	COG1231	oxidoreductase activity
BsBEST3095_19450	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3095_19460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3095_19470	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3095_19470	COG2207	Transcriptional regulator
BsBEST3095_19480	COG0456	acetyltransferase
BsBEST3095_19490	COG1309	transcriptional regulator
BsBEST3095_19500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3095_19510	COG3708	Transcriptional regulator
BsBEST3095_19520	COG2378	regulation of single-species biofilm formation
BsBEST3095_19540	COG0640	Transcriptional regulator
BsBEST3095_19550	COG0741	lytic transglycosylase activity
BsBEST3095_19560	COG2322	membrane
BsBEST3095_19590	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3095_19600	COG3239	Fatty acid desaturase
BsBEST3095_19610	COG4585	Histidine kinase
BsBEST3095_19620	COG2197	response regulator
BsBEST3095_19630	COG1388	LysM domain
BsBEST3095_19630	COG3584	3D domain protein
BsBEST3095_19640	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3095_19650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3095_19660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3095_19690	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3095_19740	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_19750	COG1657	PFAM Prenyltransferase squalene oxidase
BsBEST3095_19760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3095_19770	COG0733	neurotransmitter:sodium symporter activity
BsBEST3095_19780	COG0385	Bile acid
BsBEST3095_19790	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3095_19800	COG0567	Dehydrogenase, E1 component
BsBEST3095_19810	COG4548	von Willebrand factor, type A
BsBEST3095_19820	COG0714	Associated with various cellular activities
BsBEST3095_19830	COG2032	superoxide dismutase activity
BsBEST3095_19840	COG0791	NLP P60 protein
BsBEST3095_19840	COG1388	LysM domain
BsBEST3095_19850	COG1819	glycosyl
BsBEST3095_19860	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3095_19870	COG0534	Mate efflux family protein
BsBEST3095_19880	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3095_19890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3095_19900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3095_19920	COG2962	Rard protein
BsBEST3095_19950	COG2610	gluconate transmembrane transporter activity
BsBEST3095_19960	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3095_19970	COG1733	regulation of RNA biosynthetic process
BsBEST3095_19980	COG0778	Nitroreductase
BsBEST3095_19990	COG0400	carboxylic ester hydrolase activity
BsBEST3095_20000	COG0346	lactoylglutathione lyase activity
BsBEST3095_20020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3095_20030	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_20030	COG0793	Belongs to the peptidase S41A family
BsBEST3095_20040	COG2226	methyltransferase
BsBEST3095_20060	COG1876	peptidase activity
BsBEST3095_20070	COG0813	purine-nucleoside phosphorylase activity
BsBEST3095_20100	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3095_20140	COG4479	Belongs to the UPF0346 family
BsBEST3095_20160	COG1509	lysine 2,3-aminomutase activity
BsBEST3095_20170	COG0456	acetyltransferase
BsBEST3095_20180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3095_20190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3095_20200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3095_20210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3095_20240	COG0456	acetyltransferase
BsBEST3095_20250	COG0463	Glycosyl transferase, family 2
BsBEST3095_20280	COG4641	Protein conserved in bacteria
BsBEST3095_20290	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BsBEST3095_20300	COG1086	Polysaccharide biosynthesis protein
BsBEST3095_20320	COG3331	DNA recombination
BsBEST3095_20410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3095_20470	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BsBEST3095_20480	COG0756	dUTP diphosphatase activity
BsBEST3095_20490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_20500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3095_20520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3095_20540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3095_20540	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3095_20550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3095_20550	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3095_20560	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3095_20740	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3095_20760	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BsBEST3095_20770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3095_20820	COG3584	3D domain protein
BsBEST3095_20830	COG0587	DNA-directed DNA polymerase activity
BsBEST3095_20840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3095_20850	COG0358	DNA primase activity
BsBEST3095_20860	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3095_20880	COG2887	Belongs to the helicase family. UvrD subfamily
BsBEST3095_20940	COG3420	alginic acid biosynthetic process
BsBEST3095_20940	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3095_20950	COG4195	phage-related replication protein
BsBEST3095_20980	COG2135	peptidase activity
BsBEST3095_20990	COG1793	dna ligase
BsBEST3095_21090	COG4474	Belongs to the UPF0398 family
BsBEST3095_21110	COG1388	LysM domain
BsBEST3095_21150	COG3645	SOS response
BsBEST3095_21150	COG3646	Phage regulatory protein
BsBEST3095_21260	COG3655	Transcriptional regulator
BsBEST3095_21290	COG0582	viral genome integration into host DNA
BsBEST3095_21450	COG3655	Transcriptional regulator
BsBEST3095_21520	COG1395	domain, Protein
BsBEST3095_21560	COG0776	regulation of translation
BsBEST3095_21620	COG4373	Mu-like prophage FluMu protein gp28
BsBEST3095_21820	COG0582	viral genome integration into host DNA
BsBEST3095_21880	COG0739	heme binding
BsBEST3095_21880	COG0741	lytic transglycosylase activity
BsBEST3095_21880	COG1196	nuclear chromosome segregation
BsBEST3095_21900	COG2433	Pfam Transposase IS66
BsBEST3095_21920	COG4632	Exopolysaccharide biosynthesis protein
BsBEST3095_21920	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3095_21950	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_21980	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3095_21990	COG0463	Glycosyl transferase, family 2
BsBEST3095_22000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_22010	COG2274	protein secretion by the type I secretion system
BsBEST3095_22010	COG3271	cysteine-type peptidase activity
BsBEST3095_22040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3095_22090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3095_22120	COG5444	nuclease activity
BsBEST3095_22130	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3095_22150	COG1525	nuclease
BsBEST3095_22170	COG2746	aminoglycoside 3-N-acetyltransferase activity
BsBEST3095_22220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3095_22230	COG1086	Polysaccharide biosynthesis protein
BsBEST3095_22240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3095_22250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3095_22260	COG1846	Transcriptional regulator
BsBEST3095_22270	COG0534	Mate efflux family protein
BsBEST3095_22290	COG4698	Protein conserved in bacteria
BsBEST3095_22300	COG2755	lipolytic protein G-D-S-L family
BsBEST3095_22310	COG1999	signal sequence binding
BsBEST3095_22330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BsBEST3095_22340	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3095_22350	COG1272	protein, Hemolysin III
BsBEST3095_22360	COG0204	Acyl-transferase
BsBEST3095_22370	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3095_22380	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3095_22390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3095_22410	COG2136	Putative SAM-dependent methyltransferase
BsBEST3095_22410	COG2521	methyltransferase
BsBEST3095_22430	COG0129	dihydroxy-acid dehydratase activity
BsBEST3095_22440	COG1413	lyase activity
BsBEST3095_22450	COG1418	mRNA catabolic process
BsBEST3095_22460	COG0386	Belongs to the glutathione peroxidase family
BsBEST3095_22470	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BsBEST3095_22480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3095_22490	COG1278	Cold shock
BsBEST3095_22530	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3095_22540	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BsBEST3095_22550	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3095_22570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3095_22600	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3095_22610	COG1755	Isoprenylcysteine carboxyl methyltransferase
BsBEST3095_22620	COG3424	synthase
BsBEST3095_22630	COG2233	PERMEase
BsBEST3095_22640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3095_22650	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BsBEST3095_22670	COG0800	Aldolase
BsBEST3095_22680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3095_22690	COG1609	Transcriptional regulator
BsBEST3095_22700	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BsBEST3095_22710	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_22720	COG1199	ATP-dependent helicase activity
BsBEST3095_22740	COG0116	Belongs to the methyltransferase superfamily
BsBEST3095_22760	COG4474	Belongs to the UPF0398 family
BsBEST3095_22770	COG3359	exonuclease
BsBEST3095_22780	COG1111	helicase
BsBEST3095_22780	COG1205	dead DEAH box helicase
BsBEST3095_22790	COG2190	(PTS) system
BsBEST3095_22800	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3095_22860	COG3331	DNA recombination
BsBEST3095_22870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3095_22870	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3095_22890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BsBEST3095_22900	COG3935	DnaD domain protein
BsBEST3095_22910	COG0017	Asparaginyl-tRNA synthetase
BsBEST3095_22920	COG0436	Aminotransferase
BsBEST3095_22930	COG5353	protein conserved in bacteria
BsBEST3095_22950	COG1199	ATP-dependent helicase activity
BsBEST3095_22950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BsBEST3095_22960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BsBEST3095_22970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BsBEST3095_22980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BsBEST3095_22990	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BsBEST3095_22990	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BsBEST3095_23000	COG0617	tRNA 3'-terminal CCA addition
BsBEST3095_23010	COG0438	transferase activity, transferring glycosyl groups
BsBEST3095_23020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3095_23030	COG1803	Methylglyoxal synthase
BsBEST3095_23040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BsBEST3095_23050	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3095_23060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3095_23080	COG4347	Protein of unknown function (DUF1405)
BsBEST3095_23090	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3095_23090	COG2010	Cytochrome c
BsBEST3095_23100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3095_23110	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3095_23130	COG5582	Belongs to the UPF0302 family
BsBEST3095_23140	COG0457	Tetratricopeptide repeat
BsBEST3095_23150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BsBEST3095_23160	COG0287	Prephenate dehydrogenase
BsBEST3095_23170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BsBEST3095_23180	COG0159	tryptophan synthase activity
BsBEST3095_23190	COG0133	tryptophan synthase activity
BsBEST3095_23200	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3095_23220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BsBEST3095_23230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3095_23240	COG4401	Chorismate mutase type I
BsBEST3095_23250	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BsBEST3095_23260	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BsBEST3095_23270	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BsBEST3095_23280	COG0105	UTP biosynthetic process
BsBEST3095_23290	COG0142	geranyltranstransferase activity
BsBEST3095_23300	COG2226	methyltransferase
BsBEST3095_23310	COG0142	geranyltranstransferase activity
BsBEST3095_23330	COG0302	gtp cyclohydrolase
BsBEST3095_23340	COG0776	regulation of translation
BsBEST3095_23350	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3095_23380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BsBEST3095_23390	COG1160	GTP binding
BsBEST3095_23440	COG1304	FMN binding
BsBEST3095_23450	COG0539	negative regulation of cytoplasmic translation
BsBEST3095_23460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BsBEST3095_23480	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BsBEST3095_23490	COG2959	enzyme of heme biosynthesis
BsBEST3095_23500	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_23500	COG3773	Cell wall hydrolase
BsBEST3095_23510	COG2339	peptidase activity
BsBEST3095_23520	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3095_23530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3095_23540	COG4862	establishment of competence for transformation
BsBEST3095_23550	COG1408	metallophosphoesterase
BsBEST3095_23560	COG1388	LysM domain
BsBEST3095_23570	COG1266	CAAX protease self-immunity
BsBEST3095_23580	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3095_23590	COG4955	Helix-turn-helix domain
BsBEST3095_23600	COG1141	Ferredoxin
BsBEST3095_23610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BsBEST3095_23630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3095_23640	COG0710	3-dehydroquinate dehydratase activity
BsBEST3095_23660	COG1595	DNA-templated transcription, initiation
BsBEST3095_23670	COG5002	protein histidine kinase activity
BsBEST3095_23680	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_23690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3095_23700	COG1333	cytochrome c biogenesis protein
BsBEST3095_23710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_23720	COG1187	pseudouridine synthase activity
BsBEST3095_23730	COG0700	Nucleoside recognition
BsBEST3095_23740	COG2715	membrane protein required for spore maturation
BsBEST3095_23750	COG1686	Belongs to the peptidase S11 family
BsBEST3095_23770	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BsBEST3095_23780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BsBEST3095_23790	COG1547	Domain of unknown function (DUF309)
BsBEST3095_23800	COG0456	acetyltransferase
BsBEST3095_23810	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BsBEST3095_23820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3095_23820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3095_23830	COG0307	riboflavin synthase, alpha
BsBEST3095_23840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3095_23840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3095_23860	COG0681	Belongs to the peptidase S26 family
BsBEST3095_23880	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BsBEST3095_23910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BsBEST3095_23920	COG4086	secreted protein
BsBEST3095_23930	COG0019	diaminopimelate decarboxylase activity
BsBEST3095_23940	COG0697	spore germination
BsBEST3095_23970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3095_24010	COG1191	sigma factor activity
BsBEST3095_24020	COG2172	sigma factor antagonist activity
BsBEST3095_24030	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3095_24040	COG1686	Belongs to the peptidase S11 family
BsBEST3095_24050	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BsBEST3095_24060	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BsBEST3095_24070	COG4974	Belongs to the 'phage' integrase family
BsBEST3095_24090	COG0735	belongs to the Fur family
BsBEST3095_24100	COG1300	Membrane
BsBEST3095_24120	COG0281	malic enzyme
BsBEST3095_24130	COG1757	Na H antiporter
BsBEST3095_24140	COG1027	Aspartate ammonia-lyase
BsBEST3095_24150	COG0252	asparaginase activity
BsBEST3095_24160	COG1396	sequence-specific DNA binding
BsBEST3095_24170	COG1379	DNA repair
BsBEST3095_24180	COG0494	nUDIX hydrolase
BsBEST3095_24200	COG0667	Aldo Keto reductase
BsBEST3095_24220	COG1073	alpha beta
BsBEST3095_24240	COG4918	Iron-sulphur cluster biosynthesis
BsBEST3095_24250	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BsBEST3095_24250	COG0456	acetyltransferase
BsBEST3095_24260	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3095_24270	COG0456	acetyltransferase
BsBEST3095_24290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3095_24310	COG2211	Major facilitator Superfamily
BsBEST3095_24330	COG0346	lactoylglutathione lyase activity
BsBEST3095_24340	COG1072	(Pantothenic acid kinase))
BsBEST3095_24350	COG3048	D-serine ammonia-lyase activity
BsBEST3095_24360	COG0300	oxidoreductase activity
BsBEST3095_24370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3095_24380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3095_24390	COG4187	Peptidase family M20/M25/M40
BsBEST3095_24400	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3095_24410	COG0596	Alpha beta hydrolase
BsBEST3095_24420	COG1234	tRNA 3'-trailer cleavage
BsBEST3095_24430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BsBEST3095_24440	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3095_24450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3095_24470	COG0706	membrane insertase activity
BsBEST3095_24480	COG3361	conserved protein (COG2071)
BsBEST3095_24490	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3095_24500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3095_24510	COG0346	lactoylglutathione lyase activity
BsBEST3095_24520	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3095_24530	COG4129	membrane
BsBEST3095_24540	COG1126	abc transporter atp-binding protein
BsBEST3095_24550	COG0765	amino acid transport
BsBEST3095_24560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3095_24580	COG1597	lipid kinase activity
BsBEST3095_24590	COG2814	Major facilitator Superfamily
BsBEST3095_24600	COG0789	Transcriptional regulator
BsBEST3095_24600	COG4978	Transcriptional regulator
BsBEST3095_24610	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3095_24620	COG0022	dehydrogenase e1 component
BsBEST3095_24630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3095_24640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3095_24650	COG3426	butyrate kinase activity
BsBEST3095_24660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3095_24670	COG0280	phosphate acetyltransferase
BsBEST3095_24680	COG3829	transcription factor binding
BsBEST3095_24680	COG3290	protein histidine kinase activity
BsBEST3095_24700	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BsBEST3095_24710	COG2079	MmgE PrpD family protein
BsBEST3095_24720	COG0372	Belongs to the citrate synthase family
BsBEST3095_24730	COG1960	acyl-CoA dehydrogenase activity
BsBEST3095_24740	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3095_24750	COG0183	Belongs to the thiolase family
BsBEST3095_24760	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3095_24770	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_24790	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3095_24800	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_24810	COG0750	zinc metalloprotease
BsBEST3095_24820	COG0497	DNA recombination
BsBEST3095_24830	COG1438	arginine binding
BsBEST3095_24840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BsBEST3095_24850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BsBEST3095_24860	COG0142	geranyltranstransferase activity
BsBEST3095_24870	COG1722	exodeoxyribonuclease VII activity
BsBEST3095_24880	COG1570	exodeoxyribonuclease VII activity
BsBEST3095_24890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BsBEST3095_24900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3095_24910	COG1302	Protein conserved in bacteria
BsBEST3095_24920	COG0439	Biotin carboxylase
BsBEST3095_24930	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3095_25010	COG3854	ATPases associated with a variety of cellular activities
BsBEST3095_25030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BsBEST3095_25040	COG0006	proline dipeptidase activity
BsBEST3095_25050	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BsBEST3095_25070	COG3872	metal-dependent enzyme
BsBEST3095_25090	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3095_25100	COG1321	iron dependent repressor
BsBEST3095_25110	COG0095	Lipoate-protein ligase
BsBEST3095_25120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3095_25130	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3095_25140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3095_25150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BsBEST3095_25160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3095_25190	COG1396	sequence-specific DNA binding
BsBEST3095_25210	COG0681	Belongs to the peptidase S26 family
BsBEST3095_25260	COG4940	Competence protein ComGF
BsBEST3095_25280	COG4970	Tfp pilus assembly protein FimT
BsBEST3095_25290	COG4537	Required for transformation and DNA binding
BsBEST3095_25300	COG1459	type II secretion system
BsBEST3095_25310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BsBEST3095_25320	COG0598	Magnesium transport protein CorA
BsBEST3095_25330	COG1253	flavin adenine dinucleotide binding
BsBEST3095_25340	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3095_25350	COG1393	Belongs to the ArsC family
BsBEST3095_25370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3095_25390	COG0011	TIGRFAM Protein of
BsBEST3095_25410	COG2866	Carboxypeptidase
BsBEST3095_25420	COG1368	sulfuric ester hydrolase activity
BsBEST3095_25430	COG1940	carbohydrate kinase activity
BsBEST3095_25440	COG4483	Protein conserved in bacteria
BsBEST3095_25450	COG0457	Tetratricopeptide repeat
BsBEST3095_25450	COG0705	Rhomboid family
BsBEST3095_25470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BsBEST3095_25490	COG0438	transferase activity, transferring glycosyl groups
BsBEST3095_25520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3095_25530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3095_25540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3095_25550	COG0581	inorganic phosphate transmembrane transporter activity
BsBEST3095_25560	COG0573	inorganic phosphate transmembrane transporter activity
BsBEST3095_25570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BsBEST3095_25580	COG0768	penicillin binding
BsBEST3095_25590	COG0477	Major facilitator Superfamily
BsBEST3095_25600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3095_25610	COG2839	Protein conserved in bacteria
BsBEST3095_25620	COG5521	maltodextrose utilization protein MalA
BsBEST3095_25640	COG1388	LysM domain
BsBEST3095_25650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BsBEST3095_25660	COG4709	membrane
BsBEST3095_25670	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BsBEST3095_25680	COG0735	belongs to the Fur family
BsBEST3095_25690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3095_25710	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BsBEST3095_25720	COG0513	Belongs to the DEAD box helicase family
BsBEST3095_25740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BsBEST3095_25750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BsBEST3095_25760	COG2384	SAM-dependent methyltransferase
BsBEST3095_25770	COG2010	Cytochrome c
BsBEST3095_25780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BsBEST3095_25790	COG0358	DNA primase activity
BsBEST3095_25800	COG1671	Belongs to the UPF0178 family
BsBEST3095_25810	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BsBEST3095_25820	COG0517	IMP dehydrogenase activity
BsBEST3095_25830	COG0751	glycine-tRNA ligase activity
BsBEST3095_25840	COG0752	glycyl-tRNA synthetase alpha subunit
BsBEST3095_25850	COG1381	Involved in DNA repair and RecF pathway recombination
BsBEST3095_25870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BsBEST3095_25880	COG0295	cytidine deaminase activity
BsBEST3095_25890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BsBEST3095_25900	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BsBEST3095_25910	COG1480	7TM receptor with intracellular HD hydrolase
BsBEST3095_25920	COG1702	phosphate starvation-inducible protein PhoH
BsBEST3095_25930	COG0561	phosphatase activity
BsBEST3095_25960	COG4864	UPF0365 protein
BsBEST3095_25970	COG1030	water channel activity
BsBEST3095_25980	COG1610	YqeY-like protein
BsBEST3095_26000	COG1283	sodium-dependent phosphate transmembrane transporter activity
BsBEST3095_26010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3095_26020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BsBEST3095_26030	COG2264	protein methyltransferase activity
BsBEST3095_26040	COG0484	heat shock protein binding
BsBEST3095_26050	COG0443	Heat shock 70 kDa protein
BsBEST3095_26060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BsBEST3095_26070	COG1420	regulation of RNA biosynthetic process
BsBEST3095_26080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3095_26090	COG0481	GTPase activity
BsBEST3095_26110	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_26120	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BsBEST3095_26140	COG0268	Binds directly to 16S ribosomal RNA
BsBEST3095_26150	COG1466	dna polymerase III delta subunit
BsBEST3095_26170	COG0658	competence protein
BsBEST3095_26170	COG2333	competence protein COMEC
BsBEST3095_26190	COG2131	deaminase
BsBEST3095_26200	COG1555	photosystem II stabilization
BsBEST3095_26200	COG1596	polysaccharide export
BsBEST3095_26210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3095_26220	COG2226	methyltransferase
BsBEST3095_26230	COG0799	negative regulation of ribosome biogenesis
BsBEST3095_26240	COG1713	HD superfamily hydrolase involved in NAD metabolism
BsBEST3095_26250	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BsBEST3095_26260	COG1534	Rna-binding protein
BsBEST3095_26270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BsBEST3095_26280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3095_26290	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BsBEST3095_26300	COG2755	lipolytic protein G-D-S-L family
BsBEST3095_26310	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_26310	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_26320	COG0398	Pfam SNARE associated Golgi protein
BsBEST3095_26330	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BsBEST3095_26350	COG3209	COG3209 Rhs family protein
BsBEST3095_26370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3095_26390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3095_26400	COG0798	PFAM Bile acid sodium symporter
BsBEST3095_26410	COG0346	lactoylglutathione lyase activity
BsBEST3095_26420	COG0640	Transcriptional regulator
BsBEST3095_26430	COG3403	YqcI/YcgG family
BsBEST3095_26440	COG0457	Tetratricopeptide repeat
BsBEST3095_26470	COG5444	nuclease activity
BsBEST3095_26520	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_26520	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_26530	COG4824	toxin secretion phage lysis holin
BsBEST3095_26590	COG3778	Protein conserved in bacteria
BsBEST3095_26600	COG3299	homolog of phage Mu protein gp47
BsBEST3095_26610	COG3628	GPW Gp25 family protein
BsBEST3095_26630	COG4193	domain, Protein
BsBEST3095_26640	COG1652	LysM domain
BsBEST3095_26650	COG3953	SLT domain
BsBEST3095_26650	COG5280	Phage tail tape measure protein TP901
BsBEST3095_26780	COG4653	Phage capsid family
BsBEST3095_26790	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3095_26810	COG2369	cell adhesion
BsBEST3095_26820	COG5518	Phage portal protein
BsBEST3095_26830	COG1783	phage Terminase large subunit
BsBEST3095_26840	COG5484	DNA packaging
BsBEST3095_26860	COG3677	Transposase
BsBEST3095_26890	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BsBEST3095_26910	COG1484	DNA-dependent DNA replication
BsBEST3095_26920	COG3935	DnaD domain protein
BsBEST3095_26930	COG3723	Recombinational DNA repair protein, rece pathway
BsBEST3095_26940	COG5377	YqaJ viral recombinase family
BsBEST3095_27000	COG1476	TRANSCRIPTIONal
BsBEST3095_27010	COG3620	sequence-specific DNA binding
BsBEST3095_27030	COG0563	adenylate kinase activity
BsBEST3095_27040	COG2856	Zn peptidase
BsBEST3095_27060	COG3223	Belongs to the PsiE family
BsBEST3095_27070	COG0642	Histidine kinase
BsBEST3095_27070	COG5002	protein histidine kinase activity
BsBEST3095_27080	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_27090	COG2311	Membrane
BsBEST3095_27100	COG0454	-acetyltransferase
BsBEST3095_27110	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3095_27130	COG0730	response to heat
BsBEST3095_27140	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3095_27150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3095_27150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3095_27160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3095_27160	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3095_27170	COG2210	Belongs to the sulfur carrier protein TusA family
BsBEST3095_27180	COG1937	Protein conserved in bacteria
BsBEST3095_27210	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3095_27230	COG0789	Transcriptional regulator
BsBEST3095_27230	COG4978	Transcriptional regulator
BsBEST3095_27240	COG2814	Major facilitator Superfamily
BsBEST3095_27250	COG0456	acetyltransferase
BsBEST3095_27260	COG1253	flavin adenine dinucleotide binding
BsBEST3095_27280	COG0697	spore germination
BsBEST3095_27290	COG0583	DNA-binding transcription factor activity
BsBEST3095_27300	COG2072	flavoprotein involved in K transport
BsBEST3095_27310	COG1230	cation diffusion facilitator family transporter
BsBEST3095_27320	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3095_27330	COG0583	DNA-binding transcription factor activity
BsBEST3095_27350	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3095_27360	COG1687	branched-chain amino acid
BsBEST3095_27370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BsBEST3095_27380	COG1522	sequence-specific DNA binding
BsBEST3095_27390	COG2732	(Barnase) inhibitor
BsBEST3095_27400	COG2124	cytochrome p450
BsBEST3095_27430	COG1335	isochorismatase
BsBEST3095_27450	COG2318	DinB family
BsBEST3095_27470	COG2070	2-Nitropropane dioxygenase
BsBEST3095_27500	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3095_27530	COG3443	Belongs to the bacterial solute-binding protein 9 family
BsBEST3095_27540	COG1595	DNA-templated transcription, initiation
BsBEST3095_27550	COG0667	Aldo Keto reductase
BsBEST3095_27560	COG2851	Citrate transporter
BsBEST3095_27570	COG0583	DNA-binding transcription factor activity
BsBEST3095_27580	COG2828	Protein conserved in bacteria
BsBEST3095_27600	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_27610	COG5566	PFAM Mor transcription activator
BsBEST3095_27620	COG0596	Alpha beta hydrolase
BsBEST3095_27630	COG4991	sh3 domain protein
BsBEST3095_27640	COG4991	sh3 domain protein
BsBEST3095_27650	COG0346	lactoylglutathione lyase activity
BsBEST3095_27670	COG5577	PFAM Coat F domain
BsBEST3095_27680	COG1063	alcohol dehydrogenase
BsBEST3095_27700	COG5577	PFAM Coat F domain
BsBEST3095_27710	COG0789	Transcriptional regulator
BsBEST3095_27730	COG1064	alcohol dehydrogenase
BsBEST3095_27740	COG0693	protein deglycase activity
BsBEST3095_27750	COG1621	beta-fructofuranosidase activity
BsBEST3095_27760	COG3716	PTS system mannose fructose sorbose family IID component
BsBEST3095_27770	COG3715	PTS system
BsBEST3095_27780	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3095_27790	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3095_27800	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3095_27800	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BsBEST3095_27820	COG1113	amino acid transport
BsBEST3095_27830	COG1280	lysine exporter protein (LysE YggA)
BsBEST3095_27840	COG1378	Sugar-specific transcriptional regulator TrmB
BsBEST3095_27850	COG1595	DNA-templated transcription, initiation
BsBEST3095_27870	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BsBEST3095_27870	COG2755	lipolytic protein G-D-S-L family
BsBEST3095_27890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3095_27890	COG2124	cytochrome p450
BsBEST3095_27900	COG1309	transcriptional regulator
BsBEST3095_27910	COG2226	methyltransferase
BsBEST3095_27930	COG2116	formate transmembrane transporter activity
BsBEST3095_27940	COG5609	conserved protein (DUF2294)
BsBEST3095_27950	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3095_27960	COG2427	Protein of unknown function (DUF1641)
BsBEST3095_27980	COG0626	cystathionine gamma-synthase activity
BsBEST3095_27990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3095_28000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BsBEST3095_28010	COG2226	methyltransferase
BsBEST3095_28040	COG0768	penicillin binding
BsBEST3095_28050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BsBEST3095_28060	COG0572	uridine kinase
BsBEST3095_28070	COG0826	peptidase U32
BsBEST3095_28080	COG0826	peptidase U32
BsBEST3095_28090	COG4122	O-methyltransferase activity
BsBEST3095_28100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3095_28110	COG3906	Belongs to the UPF0473 family
BsBEST3095_28120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BsBEST3095_28130	COG4472	Bacterial protein of unknown function (DUF965)
BsBEST3095_28140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BsBEST3095_28150	COG0628	permease
BsBEST3095_28160	COG1126	abc transporter atp-binding protein
BsBEST3095_28170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3095_28180	COG0765	amino acid transport
BsBEST3095_28190	COG0765	amino acid transport
BsBEST3095_28220	COG3881	PFAM PRC-barrel domain
BsBEST3095_28230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BsBEST3095_28240	COG0457	Tetratricopeptide repeat
BsBEST3095_28250	COG0482	sulfurtransferase activity
BsBEST3095_28260	COG1104	cysteine desulfurase activity
BsBEST3095_28270	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3095_28280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BsBEST3095_28290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BsBEST3095_28300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BsBEST3095_28310	COG0124	histidyl-tRNA synthetase
BsBEST3095_28330	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_28330	COG3103	Sh3 type 3 domain protein
BsBEST3095_28330	COG4991	sh3 domain protein
BsBEST3095_28340	COG1490	D-aminoacyl-tRNA deacylase activity
BsBEST3095_28350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BsBEST3095_28360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3095_28370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3095_28370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BsBEST3095_28380	COG5416	Lipopolysaccharide assembly protein A domain
BsBEST3095_28390	COG0490	domain, Protein
BsBEST3095_28400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3095_28400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3095_28420	COG2244	polysaccharide biosynthetic process
BsBEST3095_28430	COG2323	membrane
BsBEST3095_28450	COG1862	Preprotein translocase
BsBEST3095_28460	COG0343	queuine tRNA-ribosyltransferase activity
BsBEST3095_28470	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BsBEST3095_28490	COG2255	four-way junction helicase activity
BsBEST3095_28500	COG0632	four-way junction helicase activity
BsBEST3095_28520	COG2814	Major facilitator Superfamily
BsBEST3095_28530	COG0673	inositol 2-dehydrogenase activity
BsBEST3095_28540	COG2112	serine threonine protein kinase
BsBEST3095_28580	COG1115	amino acid carrier protein
BsBEST3095_28590	COG0217	transcriptional regulatory protein
BsBEST3095_28610	COG1388	LysM domain
BsBEST3095_28620	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BsBEST3095_28630	COG0157	Belongs to the NadC ModD family
BsBEST3095_28640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BsBEST3095_28650	COG1104	cysteine desulfurase activity
BsBEST3095_28660	COG1827	regulation of RNA biosynthetic process
BsBEST3095_28670	COG0077	Prephenate dehydratase
BsBEST3095_28680	COG4492	Belongs to the UPF0735 family
BsBEST3095_28690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BsBEST3095_28700	COG3290	protein histidine kinase activity
BsBEST3095_28710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BsBEST3095_28720	COG2868	ribosomal protein
BsBEST3095_28730	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BsBEST3095_28740	COG1994	Peptidase M50
BsBEST3095_28750	COG0739	heme binding
BsBEST3095_28760	COG2894	cell division
BsBEST3095_28770	COG0850	regulation of cytokinetic process
BsBEST3095_28780	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BsBEST3095_28800	COG1077	Cell shape determining protein MreB Mrl
BsBEST3095_28810	COG2003	Belongs to the UPF0758 family
BsBEST3095_28820	COG0424	maF-like protein
BsBEST3095_28840	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BsBEST3095_28850	COG0285	dihydrofolate synthase activity
BsBEST3095_28860	COG0525	valine-tRNA ligase activity
BsBEST3095_28880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3095_28890	COG1388	LysM domain
BsBEST3095_28900	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3095_28910	COG0113	porphobilinogen synthase activity
BsBEST3095_28920	COG1587	Uroporphyrinogen-III synthase
BsBEST3095_28930	COG0181	hydroxymethylbilane synthase activity
BsBEST3095_28940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3095_28950	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BsBEST3095_28970	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BsBEST3095_28980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BsBEST3095_28990	COG0470	DNA polymerase III
BsBEST3095_28990	COG1067	ATP-dependent peptidase activity
BsBEST3095_29000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BsBEST3095_29010	COG0544	peptidyl-prolyl cis-trans isomerase activity
BsBEST3095_29020	COG0457	Tetratricopeptide repeat
BsBEST3095_29020	COG1477	protein flavinylation
BsBEST3095_29030	COG0066	3-isopropylmalate dehydratase activity
BsBEST3095_29040	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BsBEST3095_29060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BsBEST3095_29070	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3095_29080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3095_29090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BsBEST3095_29100	COG0440	acetolactate synthase activity
BsBEST3095_29110	COG0028	Belongs to the TPP enzyme family
BsBEST3095_29130	COG0454	-acetyltransferase
BsBEST3095_29140	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BsBEST3095_29150	COG0622	Phosphoesterase
BsBEST3095_29160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BsBEST3095_29170	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BsBEST3095_29180	COG5401	PFAM Sporulation and spore germination
BsBEST3095_29190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3095_29200	COG1846	Transcriptional regulator
BsBEST3095_29210	COG2197	response regulator
BsBEST3095_29220	COG0824	Thioesterase
BsBEST3095_29230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BsBEST3095_29240	COG1053	succinate dehydrogenase
BsBEST3095_29250	COG2009	succinate dehydrogenase
BsBEST3095_29260	COG1719	4-vinyl reductase, 4VR
BsBEST3095_29270	COG0527	aspartate kinase activity
BsBEST3095_29280	COG0322	excinuclease ABC activity
BsBEST3095_29290	COG3118	belongs to the thioredoxin family
BsBEST3095_29300	COG3534	alpha-L-arabinofuranosidase
BsBEST3095_29320	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BsBEST3095_29330	COG2086	electron transfer activity
BsBEST3095_29340	COG1024	Enoyl-CoA hydratase
BsBEST3095_29350	COG1309	transcriptional regulator
BsBEST3095_29360	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3095_29370	COG3766	membrane
BsBEST3095_29380	COG1193	negative regulation of DNA recombination
BsBEST3095_29390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3095_29390	COG1796	DNA polymerase
BsBEST3095_29400	COG1286	toxin biosynthetic process
BsBEST3095_29410	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BsBEST3095_29420	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3095_29430	COG0072	phenylalanine-tRNA ligase activity
BsBEST3095_29430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3095_29440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BsBEST3095_29450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3095_29470	COG3835	regulator
BsBEST3095_29480	COG0277	FAD linked oxidase domain protein
BsBEST3095_29490	COG0247	lactate metabolic process
BsBEST3095_29500	COG0346	lactoylglutathione lyase activity
BsBEST3095_29520	COG1966	Carbon starvation protein
BsBEST3095_29530	COG3534	alpha-L-arabinofuranosidase
BsBEST3095_29540	COG0395	ABC-type sugar transport system, permease component
BsBEST3095_29550	COG1175	transmembrane transport
BsBEST3095_29560	COG1653	transport
BsBEST3095_29570	COG0371	Dehydrogenase
BsBEST3095_29580	COG0647	UMP catabolic process
BsBEST3095_29590	COG0235	Class ii aldolase
BsBEST3095_29600	COG1069	ribulokinase activity
BsBEST3095_29610	COG2160	L-arabinose isomerase activity
BsBEST3095_29620	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3095_29630	COG1363	Peptidase, m42
BsBEST3095_29650	COG3326	Membrane
BsBEST3095_29660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BsBEST3095_29670	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BsBEST3095_29680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BsBEST3095_29700	COG1346	cytolysis
BsBEST3095_29710	COG1380	Effector of murein hydrolase LrgA
BsBEST3095_29720	COG3279	Response regulator of the LytR AlgR family
BsBEST3095_29730	COG3275	phosphorelay sensor kinase activity
BsBEST3095_29740	COG1011	Hydrolase
BsBEST3095_29750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3095_29770	COG0398	Pfam SNARE associated Golgi protein
BsBEST3095_29780	COG1484	DNA-dependent DNA replication
BsBEST3095_29790	COG3611	Membrane attachment protein
BsBEST3095_29800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BsBEST3095_29810	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BsBEST3095_29820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3095_29830	COG1733	regulation of RNA biosynthetic process
BsBEST3095_29840	COG2814	Major facilitator Superfamily
BsBEST3095_29850	COG0656	L-ascorbic acid biosynthetic process
BsBEST3095_29860	COG0237	dephospho-CoA kinase activity
BsBEST3095_29870	COG1971	Probably functions as a manganese efflux pump
BsBEST3095_29880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BsBEST3095_29890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3095_29890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3095_29900	COG5002	protein histidine kinase activity
BsBEST3095_29910	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_29920	COG0039	L-malate dehydrogenase activity
BsBEST3095_29930	COG0538	isocitrate dehydrogenase activity
BsBEST3095_29940	COG0372	Belongs to the citrate synthase family
BsBEST3095_29950	COG2707	UPF0756 membrane protein
BsBEST3095_29960	COG0628	permease
BsBEST3095_29970	COG3030	protein affecting phage T7 exclusion by the F plasmid
BsBEST3095_29980	COG0469	pyruvate kinase activity
BsBEST3095_29990	COG0205	6-phosphofructokinase activity
BsBEST3095_30000	COG0825	malonyl-CoA metabolic process
BsBEST3095_30010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BsBEST3095_30020	COG0281	malic enzyme
BsBEST3095_30030	COG0587	DNA-directed DNA polymerase activity
BsBEST3095_30070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BsBEST3095_30090	COG4109	DRTGG domain
BsBEST3095_30100	COG0730	response to heat
BsBEST3095_30110	COG1473	amidohydrolase
BsBEST3095_30120	COG0196	riboflavin kinase activity
BsBEST3095_30130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3095_30140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BsBEST3095_30150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3095_30160	COG1126	abc transporter atp-binding protein
BsBEST3095_30170	COG0765	amino acid transport
BsBEST3095_30180	COG0765	amino acid transport
BsBEST3095_30190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3095_30200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3095_30210	COG0454	-acetyltransferase
BsBEST3095_30220	COG0583	DNA-binding transcription factor activity
BsBEST3095_30230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3095_30240	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_30260	COG0165	Argininosuccinate lyase
BsBEST3095_30270	COG0137	argininosuccinate synthase activity
BsBEST3095_30280	COG0521	Mo-molybdopterin cofactor biosynthetic process
BsBEST3095_30290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BsBEST3095_30300	COG0827	DNA restriction-modification system
BsBEST3095_30310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BsBEST3095_30320	COG3874	Sporulation protein YtfJ
BsBEST3095_30340	COG1714	RDD family
BsBEST3095_30350	COG0616	signal peptide processing
BsBEST3095_30360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3095_30370	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BsBEST3095_30380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3095_30400	COG0301	tRNA thio-modification
BsBEST3095_30410	COG1104	cysteine desulfurase activity
BsBEST3095_30420	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3095_30430	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BsBEST3095_30440	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3095_30450	COG1309	transcriptional regulator
BsBEST3095_30460	COG1956	GAF domain-containing protein
BsBEST3095_30470	COG2199	diguanylate cyclase activity
BsBEST3095_30470	COG2203	Gaf domain
BsBEST3095_30480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BsBEST3095_30500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3095_30510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3095_30520	COG0454	-acetyltransferase
BsBEST3095_30530	COG0517	IMP dehydrogenase activity
BsBEST3095_30540	COG0123	including yeast histone deacetylase and acetoin utilization protein
BsBEST3095_30550	COG1360	Flagellar Motor Protein
BsBEST3095_30560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3095_30570	COG1609	Transcriptional regulator
BsBEST3095_30580	COG1605	Chorismate mutase
BsBEST3095_30580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BsBEST3095_30590	COG3118	belongs to the thioredoxin family
BsBEST3095_30600	COG4980	gas vesicle protein
BsBEST3095_30610	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3095_30620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BsBEST3095_30630	COG1674	ftsk spoiiie
BsBEST3095_30640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3095_30650	COG4848	Belongs to the UPF0354 family
BsBEST3095_30660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_30680	COG1363	Peptidase, m42
BsBEST3095_30690	COG5584	Small secreted protein
BsBEST3095_30700	COG0281	malic enzyme
BsBEST3095_30710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3095_30720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BsBEST3095_30740	COG0510	thiamine kinase activity
BsBEST3095_30750	COG1523	belongs to the glycosyl hydrolase 13 family
BsBEST3095_30760	COG1597	lipid kinase activity
BsBEST3095_30780	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3095_30790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3095_30800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3095_30810	COG2252	PERMEase
BsBEST3095_30820	COG4473	ABC transporter
BsBEST3095_30830	COG1131	(ABC) transporter
BsBEST3095_30850	COG1349	DNA-binding transcription factor activity
BsBEST3095_30860	COG1187	pseudouridine synthase activity
BsBEST3095_30870	COG2244	polysaccharide biosynthetic process
BsBEST3095_30880	COG2081	HI0933 family
BsBEST3095_30890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BsBEST3095_30910	COG5578	integral membrane protein
BsBEST3095_30920	COG0673	inositol 2-dehydrogenase activity
BsBEST3095_30930	COG1653	transport
BsBEST3095_30940	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3095_30950	COG4209	transmembrane transport
BsBEST3095_30960	COG2207	Transcriptional regulator
BsBEST3095_30970	COG1653	transport
BsBEST3095_30980	COG0395	ABC-type sugar transport system, permease component
BsBEST3095_30990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3095_31000	COG2124	cytochrome p450
BsBEST3095_31010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BsBEST3095_31020	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BsBEST3095_31030	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3095_31040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3095_31050	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BsBEST3095_31060	COG1073	alpha beta
BsBEST3095_31070	COG1609	Transcriptional regulator
BsBEST3095_31080	COG1653	transport
BsBEST3095_31090	COG1175	transmembrane transport
BsBEST3095_31100	COG0395	ABC-type sugar transport system, permease component
BsBEST3095_31110	COG1486	melibiose metabolic process
BsBEST3095_31120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3095_31130	COG0495	leucyl-tRNA aminoacylation
BsBEST3095_31150	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3095_31150	COG2202	Pas domain
BsBEST3095_31160	COG2814	Major facilitator Superfamily
BsBEST3095_31170	COG2433	Pfam Transposase IS66
BsBEST3095_31180	COG0577	efflux transmembrane transporter activity
BsBEST3095_31190	COG1136	(ABC) transporter
BsBEST3095_31200	COG2205	protein histidine kinase activity
BsBEST3095_31210	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_31220	COG0577	efflux transmembrane transporter activity
BsBEST3095_31230	COG1136	(ABC) transporter
BsBEST3095_31260	COG1131	(ABC) transporter
BsBEST3095_31270	COG1725	Transcriptional regulator
BsBEST3095_31290	COG1242	4 iron, 4 sulfur cluster binding
BsBEST3095_31300	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BsBEST3095_31320	COG2267	carboxylic ester hydrolase activity
BsBEST3095_31330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BsBEST3095_31340	COG1113	amino acid transport
BsBEST3095_31350	COG0367	asparagine synthase
BsBEST3095_31360	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BsBEST3095_31370	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BsBEST3095_31390	COG1506	peptidase
BsBEST3095_31400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3095_31410	COG1116	anion transmembrane transporter activity
BsBEST3095_31420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3095_31430	COG0494	nUDIX hydrolase
BsBEST3095_31440	COG4824	toxin secretion phage lysis holin
BsBEST3095_31450	COG0783	Belongs to the Dps family
BsBEST3095_31480	COG1854	S-ribosylhomocysteine lyase activity
BsBEST3095_31490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BsBEST3095_31500	COG0288	reversible hydration of carbon dioxide
BsBEST3095_31510	COG0254	rRNA binding
BsBEST3095_31520	COG1271	oxidase subunit
BsBEST3095_31530	COG1294	oxidase, subunit
BsBEST3095_31550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3095_31560	COG1321	iron dependent repressor
BsBEST3095_31560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3095_31570	COG1121	(ABC) transporter
BsBEST3095_31580	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3095_31590	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3095_31600	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3095_31610	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BsBEST3095_31620	COG0596	Alpha beta hydrolase
BsBEST3095_31630	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BsBEST3095_31640	COG1169	isochorismate synthase
BsBEST3095_31650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3095_31660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3095_31670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3095_31680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3095_31690	COG0438	transferase activity, transferring glycosyl groups
BsBEST3095_31710	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3095_31720	COG0438	transferase activity, transferring glycosyl groups
BsBEST3095_31730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3095_31740	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BsBEST3095_31750	COG0058	SHG alpha-glucan phosphorylase activity
BsBEST3095_31760	COG0297	glycogen (starch) synthase activity
BsBEST3095_31770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3095_31780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3095_31790	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BsBEST3095_31800	COG3859	Proton-coupled thiamine transporter YuaJ
BsBEST3095_31810	COG1247	-acetyltransferase
BsBEST3095_31820	COG2268	Band 7 protein
BsBEST3095_31830	COG1585	Membrane protein implicated in regulation of membrane protease activity
BsBEST3095_31840	COG2318	DinB family
BsBEST3095_31860	COG1454	alcohol dehydrogenase
BsBEST3095_31870	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_31880	COG1510	regulation of RNA biosynthetic process
BsBEST3095_31900	COG0569	domain protein
BsBEST3095_31910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3095_31920	COG4682	membrane
BsBEST3095_31930	COG1705	Flagellar rod assembly protein muramidase FlgJ
BsBEST3095_31940	COG0477	Major facilitator Superfamily
BsBEST3095_31950	COG5553	Cysteine dioxygenase type I
BsBEST3095_31960	COG1968	undecaprenyl-diphosphatase activity
BsBEST3095_31970	COG0628	permease
BsBEST3095_31980	COG0673	inositol 2-dehydrogenase activity
BsBEST3095_31990	COG4806	L-rhamnose isomerase
BsBEST3095_32000	COG3254	rhamnose metabolic process
BsBEST3095_32010	COG1070	Carbohydrate kinase
BsBEST3095_32020	COG1349	DNA-binding transcription factor activity
BsBEST3095_32030	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_32030	COG3347	Dehydrogenase
BsBEST3095_32040	COG0840	transmembrane signaling receptor activity
BsBEST3095_32050	COG0840	transmembrane signaling receptor activity
BsBEST3095_32070	COG0840	transmembrane signaling receptor activity
BsBEST3095_32080	COG0840	transmembrane signaling receptor activity
BsBEST3095_32110	COG0432	Pfam Uncharacterised protein family UPF0047
BsBEST3095_32130	COG0366	Alpha amylase catalytic
BsBEST3095_32140	COG1253	flavin adenine dinucleotide binding
BsBEST3095_32150	COG2738	Putative neutral zinc metallopeptidase
BsBEST3095_32180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BsBEST3095_32210	COG0166	Belongs to the GPI family
BsBEST3095_32220	COG1979	alcohol dehydrogenase
BsBEST3095_32230	COG1979	alcohol dehydrogenase
BsBEST3095_32240	COG2155	Conserved Protein
BsBEST3095_32250	COG1098	S1 RNA binding domain
BsBEST3095_32260	COG0436	Aminotransferase
BsBEST3095_32270	COG1522	sequence-specific DNA binding
BsBEST3095_32280	COG2267	carboxylic ester hydrolase activity
BsBEST3095_32300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BsBEST3095_32310	COG2205	protein histidine kinase activity
BsBEST3095_32330	COG5018	Exonuclease
BsBEST3095_32350	COG2814	Major facilitator Superfamily
BsBEST3095_32360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3095_32370	COG3011	Protein conserved in bacteria
BsBEST3095_32390	COG3290	protein histidine kinase activity
BsBEST3095_32400	COG4565	transcriptional regulatory protein
BsBEST3095_32410	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3095_32420	COG3845	ABC transporter
BsBEST3095_32430	COG4603	Belongs to the binding-protein-dependent transport system permease family
BsBEST3095_32440	COG1079	Belongs to the binding-protein-dependent transport system permease family
BsBEST3095_32450	COG3493	citrate carrier protein
BsBEST3095_32470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3095_32470	COG2111	Na H antiporter
BsBEST3095_32480	COG2111	Na H antiporter
BsBEST3095_32490	COG1006	Multisubunit Na H antiporter MnhC subunit
BsBEST3095_32500	COG0651	ATP synthesis coupled electron transport
BsBEST3095_32510	COG1863	multisubunit Na H antiporter MnhE subunit
BsBEST3095_32520	COG2212	antiporter activity
BsBEST3095_32530	COG1320	monovalent cation:proton antiporter activity
BsBEST3095_32540	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3095_32550	COG2197	response regulator
BsBEST3095_32560	COG4585	Histidine kinase
BsBEST3095_32590	COG0142	geranyltranstransferase activity
BsBEST3095_32620	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BsBEST3095_32630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BsBEST3095_32640	COG1335	isochorismatase
BsBEST3095_32650	COG5506	Protein of unknown function (DUF1694)
BsBEST3095_32680	COG0628	permease
BsBEST3095_32710	COG1418	mRNA catabolic process
BsBEST3095_32720	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_32740	COG1511	domain protein
BsBEST3095_32750	COG0433	COG0433 Predicted ATPase
BsBEST3095_32750	COG1674	ftsk spoiiie
BsBEST3095_32760	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3095_32770	COG5417	Belongs to the EsaB family
BsBEST3095_32780	COG4842	Belongs to the WXG100 family
BsBEST3095_32790	COG2508	Transcriptional regulator
BsBEST3095_32790	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3095_32800	COG0686	Belongs to the AlaDH PNT family
BsBEST3095_32810	COG5634	Uncharacterized conserved protein (DUF2278)
BsBEST3095_32820	COG3251	PFAM MbtH domain protein
BsBEST3095_32830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_32840	COG1535	isochorismatase
BsBEST3095_32840	COG3433	isochorismatase activity
BsBEST3095_32850	COG1021	2,3-dihydroxybenzoate-AMP ligase
BsBEST3095_32860	COG1169	isochorismate synthase
BsBEST3095_32870	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_32880	COG2819	hydrolase of the alpha beta superfamily
BsBEST3095_32890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3095_32900	COG1268	BioY protein
BsBEST3095_32910	COG2056	Na+-H+ antiporter family
BsBEST3095_32920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BsBEST3095_32930	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BsBEST3095_32940	COG3584	3D domain protein
BsBEST3095_32960	COG1252	NADH dehydrogenase
BsBEST3095_32970	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3095_32990	COG0516	GMP reductase activity
BsBEST3095_33000	COG2808	Putative FMN-binding domain
BsBEST3095_33010	COG0456	acetyltransferase
BsBEST3095_33020	COG0316	Belongs to the HesB IscA family
BsBEST3095_33030	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BsBEST3095_33040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3095_33050	COG4844	belongs to the
BsBEST3095_33060	COG1252	NADH dehydrogenase
BsBEST3095_33070	COG4837	Protein of unknown function (DUF1462)
BsBEST3095_33080	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BsBEST3095_33090	COG4946	Tricorn protease homolog
BsBEST3095_33090	COG1506	peptidase
BsBEST3095_33090	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3095_33100	COG0083	homoserine kinase activity
BsBEST3095_33110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BsBEST3095_33120	COG0460	homoserine dehydrogenase
BsBEST3095_33130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3095_33140	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3095_33150	COG0647	UMP catabolic process
BsBEST3095_33160	COG2445	Protein of unknown function DUF86
BsBEST3095_33170	COG4470	Protein conserved in bacteria
BsBEST3095_33190	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BsBEST3095_33200	COG0739	heme binding
BsBEST3095_33220	COG3377	Domain of unknown function (DUF1805)
BsBEST3095_33230	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3095_33240	COG0730	response to heat
BsBEST3095_33250	COG1801	Protein of unknown function DUF72
BsBEST3095_33270	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3095_33280	COG2508	Transcriptional regulator
BsBEST3095_33290	COG2233	PERMEase
BsBEST3095_33300	COG2233	PERMEase
BsBEST3095_33310	COG3195	allantoin biosynthetic process
BsBEST3095_33310	COG3648	Uricase
BsBEST3095_33320	COG2351	hydroxyisourate hydrolase activity
BsBEST3095_33340	COG2080	2 iron, 2 sulfur cluster binding
BsBEST3095_33350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BsBEST3095_33360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BsBEST3095_33370	COG2068	MobA-Related Protein
BsBEST3095_33380	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BsBEST3095_33390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BsBEST3095_33400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3095_33410	COG2356	endonuclease I
BsBEST3095_33420	COG3842	ATPase activity
BsBEST3095_33430	COG2188	Transcriptional regulator
BsBEST3095_33440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3095_33450	COG0395	ABC-type sugar transport system, permease component
BsBEST3095_33460	COG1175	transmembrane transport
BsBEST3095_33470	COG1653	transport
BsBEST3095_33480	COG2222	sugar isomerase
BsBEST3095_33490	COG0322	excinuclease ABC activity
BsBEST3095_33500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3095_33530	COG0346	lactoylglutathione lyase activity
BsBEST3095_33540	COG0640	Transcriptional regulator
BsBEST3095_33550	COG0719	Fe-S assembly protein
BsBEST3095_33560	COG0822	iron-sulfur transferase activity
BsBEST3095_33570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3095_33580	COG0719	Fe-S assembly protein
BsBEST3095_33590	COG0396	ATPase activity
BsBEST3095_33610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3095_33620	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3095_33630	COG2011	ABC-type metal ion transport system permease component
BsBEST3095_33640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BsBEST3095_33660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3095_33670	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3095_33690	COG0509	glycine decarboxylation via glycine cleavage system
BsBEST3095_33700	COG1393	Belongs to the ArsC family
BsBEST3095_33710	COG1960	acyl-CoA dehydrogenase activity
BsBEST3095_33720	COG0183	Belongs to the thiolase family
BsBEST3095_33730	COG1024	Enoyl-CoA hydratase
BsBEST3095_33730	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3095_33750	COG0506	proline dehydrogenase activity
BsBEST3095_33770	COG5577	PFAM Coat F domain
BsBEST3095_33780	COG1846	Transcriptional regulator
BsBEST3095_33790	COG0477	Major facilitator Superfamily
BsBEST3095_33800	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3095_33810	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_33820	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_33830	COG0583	DNA-binding transcription factor activity
BsBEST3095_33850	COG1120	ATPase activity
BsBEST3095_33890	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_33900	COG0783	Belongs to the Dps family
BsBEST3095_33910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3095_33920	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_33930	COG2205	protein histidine kinase activity
BsBEST3095_33930	COG2770	Histidine kinase
BsBEST3095_33950	COG1309	transcriptional regulator
BsBEST3095_33960	COG0114	fumarate hydratase activity
BsBEST3095_33980	COG0697	spore germination
BsBEST3095_33990	COG0814	amino acid
BsBEST3095_34020	COG2197	response regulator
BsBEST3095_34030	COG4585	Histidine kinase
BsBEST3095_34040	COG4758	membrane
BsBEST3095_34050	COG3595	metallopeptidase activity
BsBEST3095_34060	COG1842	Phage shock protein A
BsBEST3095_34070	COG4758	membrane
BsBEST3095_34080	COG2814	Major facilitator Superfamily
BsBEST3095_34090	COG2096	Adenosyltransferase
BsBEST3095_34100	COG1120	ATPase activity
BsBEST3095_34110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3095_34120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3095_34130	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_34140	COG3386	PFAM SMP-30 Gluconolaconase
BsBEST3095_34150	COG2205	protein histidine kinase activity
BsBEST3095_34160	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_34180	COG1191	sigma factor activity
BsBEST3095_34200	COG2140	Oxalate decarboxylase
BsBEST3095_34220	COG0577	efflux transmembrane transporter activity
BsBEST3095_34230	COG1136	(ABC) transporter
BsBEST3095_34240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3095_34250	COG1120	ATPase activity
BsBEST3095_34260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3095_34270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3095_34280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3095_34290	COG0531	amino acid
BsBEST3095_34310	COG1988	membrane-bound metal-dependent
BsBEST3095_34320	COG1368	sulfuric ester hydrolase activity
BsBEST3095_34330	COG1910	domain protein
BsBEST3095_34340	COG0725	ABC transporter, periplasmic molybdate-binding protein
BsBEST3095_34350	COG4149	molybdate abc transporter
BsBEST3095_34360	COG0656	L-ascorbic acid biosynthetic process
BsBEST3095_34380	COG0025	NhaP-type Na H and K H
BsBEST3095_34390	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3095_34400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3095_34410	COG3973	AAA domain
BsBEST3095_34420	COG2860	membrane
BsBEST3095_34430	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3095_34440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BsBEST3095_34450	COG2217	Heavy metal translocating P-type atpase
BsBEST3095_34460	COG2217	Heavy metal translocating P-type atpase
BsBEST3095_34470	COG2608	mercury ion transmembrane transporter activity
BsBEST3095_34480	COG1937	Protein conserved in bacteria
BsBEST3095_34490	COG0673	inositol 2-dehydrogenase activity
BsBEST3095_34500	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3095_34510	COG1289	transmembrane transporter activity
BsBEST3095_34530	COG2076	Multidrug Resistance protein
BsBEST3095_34540	COG1309	transcriptional regulator
BsBEST3095_34550	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_34560	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BsBEST3095_34570	COG0557	exoribonuclease II activity
BsBEST3095_34580	COG1647	Serine aminopeptidase, S33
BsBEST3095_34590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3095_34600	COG0596	Alpha beta hydrolase
BsBEST3095_34610	COG1476	TRANSCRIPTIONal
BsBEST3095_34620	COG1396	sequence-specific DNA binding
BsBEST3095_34630	COG1396	sequence-specific DNA binding
BsBEST3095_34640	COG1733	regulation of RNA biosynthetic process
BsBEST3095_34650	COG0840	transmembrane signaling receptor activity
BsBEST3095_34660	COG1174	glycine betaine transport
BsBEST3095_34670	COG1732	Glycine betaine
BsBEST3095_34680	COG1174	glycine betaine transport
BsBEST3095_34690	COG0517	IMP dehydrogenase activity
BsBEST3095_34690	COG1125	glycine betaine transport
BsBEST3095_34700	COG1510	regulation of RNA biosynthetic process
BsBEST3095_34740	COG5658	integral membrane protein
BsBEST3095_34750	COG0640	Transcriptional regulator
BsBEST3095_34760	COG1174	glycine betaine transport
BsBEST3095_34770	COG1732	Glycine betaine
BsBEST3095_34780	COG1174	glycine betaine transport
BsBEST3095_34790	COG1125	glycine betaine transport
BsBEST3095_34790	COG0517	IMP dehydrogenase activity
BsBEST3095_34800	COG1510	regulation of RNA biosynthetic process
BsBEST3095_34810	COG2095	MarC family integral membrane protein
BsBEST3095_34830	COG3064	Membrane
BsBEST3095_34840	COG4640	response to antibiotic
BsBEST3095_34850	COG0456	acetyltransferase
BsBEST3095_34860	COG0148	phosphopyruvate hydratase activity
BsBEST3095_34870	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BsBEST3095_34880	COG0149	triose-phosphate isomerase activity
BsBEST3095_34890	COG0126	phosphoglycerate kinase activity
BsBEST3095_34900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3095_34910	COG2390	Transcriptional regulator
BsBEST3095_34920	COG2814	Major facilitator Superfamily
BsBEST3095_34930	COG1609	Transcriptional regulator
BsBEST3095_34940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3095_34950	COG0583	DNA-binding transcription factor activity
BsBEST3095_34960	COG0697	spore germination
BsBEST3095_34970	COG1113	amino acid transport
BsBEST3095_34980	COG3858	chitin binding
BsBEST3095_34990	COG1556	Lactate utilization protein
BsBEST3095_35000	COG1139	Iron-sulfur cluster binding protein
BsBEST3095_35010	COG0247	lactate metabolic process
BsBEST3095_35020	COG2197	response regulator
BsBEST3095_35030	COG4585	Histidine kinase
BsBEST3095_35040	COG0842	Transport permease protein
BsBEST3095_35050	COG1131	(ABC) transporter
BsBEST3095_35060	COG0596	Alpha beta hydrolase
BsBEST3095_35070	COG2208	phosphoserine phosphatase activity
BsBEST3095_35080	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BsBEST3095_35090	COG1874	Beta-galactosidase
BsBEST3095_35100	COG3833	ABC-type maltose transport systems, permease component
BsBEST3095_35110	COG1175	transmembrane transport
BsBEST3095_35120	COG2182	Extracellular solute-binding protein
BsBEST3095_35130	COG1609	Transcriptional regulator
BsBEST3095_35140	COG2186	Transcriptional regulator
BsBEST3095_35150	COG1620	l-lactate permease
BsBEST3095_35160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BsBEST3095_35180	COG5039	Polysaccharide pyruvyl transferase
BsBEST3095_35190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3095_35200	COG0110	maltose O-acetyltransferase activity
BsBEST3095_35210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BsBEST3095_35220	COG2244	polysaccharide biosynthetic process
BsBEST3095_35230	COG1216	Glycosyl transferase, family 2
BsBEST3095_35240	COG5039	Polysaccharide pyruvyl transferase
BsBEST3095_35250	COG1216	Glycosyl transferase, family 2
BsBEST3095_35270	COG0438	transferase activity, transferring glycosyl groups
BsBEST3095_35280	COG1215	transferase activity, transferring glycosyl groups
BsBEST3095_35290	COG0438	transferase activity, transferring glycosyl groups
BsBEST3095_35300	COG1086	Polysaccharide biosynthesis protein
BsBEST3095_35310	COG0489	protein tyrosine kinase activity
BsBEST3095_35320	COG3944	biosynthesis protein
BsBEST3095_35330	COG1396	sequence-specific DNA binding
BsBEST3095_35340	COG2272	Belongs to the type-B carboxylesterase lipase family
BsBEST3095_35360	COG3479	Phenolic acid decarboxylase
BsBEST3095_35380	COG1794	racemase activity, acting on amino acids and derivatives
BsBEST3095_35390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3095_35400	COG1621	beta-fructofuranosidase activity
BsBEST3095_35410	COG1621	beta-fructofuranosidase activity
BsBEST3095_35420	COG0531	amino acid
BsBEST3095_35430	COG1309	transcriptional regulator
BsBEST3095_35440	COG2076	Multidrug Resistance protein
BsBEST3095_35450	COG2076	Multidrug Resistance protein
BsBEST3095_35470	COG0277	FAD linked oxidase domain protein
BsBEST3095_35480	COG3621	Patatin-like phospholipase
BsBEST3095_35490	COG0740	serine-type endopeptidase activity
BsBEST3095_35500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3095_35510	COG0366	Alpha amylase catalytic
BsBEST3095_35520	COG1554	hydrolase, family 65, central catalytic
BsBEST3095_35530	COG5521	maltodextrose utilization protein MalA
BsBEST3095_35540	COG3833	ABC-type maltose transport systems, permease component
BsBEST3095_35550	COG1175	transmembrane transport
BsBEST3095_35560	COG2182	Extracellular solute-binding protein
BsBEST3095_35570	COG0366	Alpha amylase catalytic
BsBEST3095_35580	COG1609	Transcriptional regulator
BsBEST3095_35590	COG1611	Belongs to the LOG family
BsBEST3095_35600	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3095_35620	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3095_35630	COG0288	reversible hydration of carbon dioxide
BsBEST3095_35640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3095_35650	COG0577	efflux transmembrane transporter activity
BsBEST3095_35660	COG1136	(ABC) transporter
BsBEST3095_35670	COG5002	protein histidine kinase activity
BsBEST3095_35680	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_35700	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BsBEST3095_35710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3095_35720	COG1481	regulation of sporulation
BsBEST3095_35730	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BsBEST3095_35740	COG1660	Displays ATPase and GTPase activities
BsBEST3095_35750	COG1051	belongs to the nudix hydrolase family
BsBEST3095_35760	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3095_35770	COG0791	NLP P60 protein
BsBEST3095_35770	COG3883	PFAM NLP P60 protein
BsBEST3095_35780	COG0457	Tetratricopeptide repeat
BsBEST3095_35790	COG1132	(ABC) transporter
BsBEST3095_35830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BsBEST3095_35830	COG0140	phosphoribosyl-ATP diphosphatase activity
BsBEST3095_35840	COG0107	imidazoleglycerol-phosphate synthase activity
BsBEST3095_35850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BsBEST3095_35860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BsBEST3095_35870	COG0131	Imidazoleglycerol-phosphate dehydratase
BsBEST3095_35880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BsBEST3095_35890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BsBEST3095_35900	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BsBEST3095_35910	COG4990	cell redox homeostasis
BsBEST3095_35920	COG5297	Belongs to the glycosyl hydrolase family 6
BsBEST3095_35930	COG0110	maltose O-acetyltransferase activity
BsBEST3095_35940	COG0546	phosphoglycolate phosphatase activity
BsBEST3095_35950	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BsBEST3095_35960	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BsBEST3095_35970	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BsBEST3095_35980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BsBEST3095_35990	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3095_36000	COG2188	Transcriptional regulator
BsBEST3095_36010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3095_36020	COG1846	Transcriptional regulator
BsBEST3095_36030	COG2124	cytochrome p450
BsBEST3095_36050	COG1846	Transcriptional regulator
BsBEST3095_36060	COG2814	Major facilitator Superfamily
BsBEST3095_36070	COG1950	PFAM Membrane protein of
BsBEST3095_36080	COG1983	PspC domain protein
BsBEST3095_36090	COG3595	metallopeptidase activity
BsBEST3095_36120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3095_36130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BsBEST3095_36140	COG0556	nucleotide-excision repair
BsBEST3095_36150	COG4897	Protein conserved in bacteria
BsBEST3095_36160	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3095_36160	COG3848	Pyruvate phosphate dikinase
BsBEST3095_36170	COG1309	transcriptional regulator
BsBEST3095_36180	COG2814	Major facilitator Superfamily
BsBEST3095_36190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3095_36210	COG0793	Belongs to the peptidase S41A family
BsBEST3095_36210	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3095_36220	COG2177	Part of the ABC transporter FtsEX involved in
BsBEST3095_36230	COG2884	Cell division ATP-binding protein ftsE
BsBEST3095_36240	COG2010	Cytochrome c
BsBEST3095_36250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3095_36260	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BsBEST3095_36270	COG0653	protein targeting
BsBEST3095_36280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BsBEST3095_36300	COG1516	flagellar protein fliS
BsBEST3095_36310	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BsBEST3095_36320	COG1334	flagellar protein FlaG
BsBEST3095_36330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3095_36340	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BsBEST3095_36350	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BsBEST3095_36370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3095_36380	COG4786	Flagellar basal body rod
BsBEST3095_36380	COG1256	bacterial-type flagellum assembly
BsBEST3095_36390	COG3418	PFAM FlgN family protein
BsBEST3095_36400	COG2747	anti-sigma28 factor FlgM
BsBEST3095_36420	COG1040	competence protein
BsBEST3095_36440	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BsBEST3095_36450	COG1307	EDD domain protein, DegV family
BsBEST3095_36460	COG2197	response regulator
BsBEST3095_36470	COG4585	Histidine kinase
BsBEST3095_36480	COG1739	Uncharacterized protein family UPF0029
BsBEST3095_36490	COG1316	TRANSCRIPTIONal
BsBEST3095_36500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3095_36510	COG0438	transferase activity, transferring glycosyl groups
BsBEST3095_36520	COG1215	transferase activity, transferring glycosyl groups
BsBEST3095_36530	COG3206	protein involved in exopolysaccharide biosynthesis
BsBEST3095_36540	COG3307	-O-antigen
BsBEST3095_36550	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3095_36560	COG0297	glycogen (starch) synthase activity
BsBEST3095_36560	COG0438	transferase activity, transferring glycosyl groups
BsBEST3095_36570	COG2244	polysaccharide biosynthetic process
BsBEST3095_36600	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3095_36600	COG2247	cell wall binding repeat
BsBEST3095_36610	COG2247	cell wall binding repeat
BsBEST3095_36610	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3095_36630	COG1316	TRANSCRIPTIONal
BsBEST3095_36640	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BsBEST3095_36650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3095_36660	COG1215	transferase activity, transferring glycosyl groups
BsBEST3095_36660	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3095_36670	COG0463	Glycosyl transferase, family 2
BsBEST3095_36690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3095_36700	COG1134	teichoic acid transport
BsBEST3095_36710	COG1682	transport, permease protein
BsBEST3095_36720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3095_36730	COG0438	transferase activity, transferring glycosyl groups
BsBEST3095_36740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BsBEST3095_36750	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BsBEST3095_36760	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3095_36780	COG4193	domain, Protein
BsBEST3095_36790	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3095_36800	COG0697	spore germination
BsBEST3095_36810	COG0814	amino acid
BsBEST3095_36830	COG2814	Major facilitator Superfamily
BsBEST3095_36840	COG1316	TRANSCRIPTIONal
BsBEST3095_36850	COG0561	phosphatase activity
BsBEST3095_36860	COG0791	NLP P60 protein
BsBEST3095_36880	COG2843	Capsule synthesis protein
BsBEST3095_36900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3095_36910	COG1609	Transcriptional regulator
BsBEST3095_36920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3095_36930	COG1869	D-ribose catabolic process
BsBEST3095_36940	COG1129	ABC transporter
BsBEST3095_36950	COG1172	Belongs to the binding-protein-dependent transport system permease family
BsBEST3095_36960	COG1879	ABC-type sugar transport system periplasmic component
BsBEST3095_36970	COG3103	Sh3 type 3 domain protein
BsBEST3095_36990	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3095_37000	COG3527	Alpha-acetolactate decarboxylase
BsBEST3095_37010	COG0028	Belongs to the TPP enzyme family
BsBEST3095_37020	COG0583	DNA-binding transcription factor activity
BsBEST3095_37030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3095_37060	COG5337	Spore coat protein CotH
BsBEST3095_37080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3095_37100	COG0405	Gamma-glutamyltransferase
BsBEST3095_37110	COG1522	sequence-specific DNA binding
BsBEST3095_37120	COG2059	Chromate
BsBEST3095_37130	COG2059	Chromate
BsBEST3095_37150	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3095_37160	COG0583	DNA-binding transcription factor activity
BsBEST3095_37170	COG1515	deoxyribonuclease V activity
BsBEST3095_37180	COG2849	repeat protein
BsBEST3095_37190	COG5444	nuclease activity
BsBEST3095_37220	COG3878	Protein conserved in bacteria
BsBEST3095_37230	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3095_37240	COG4464	protein tyrosine phosphatase activity
BsBEST3095_37250	COG0489	protein tyrosine kinase activity
BsBEST3095_37260	COG3944	biosynthesis protein
BsBEST3095_37280	COG4715	Zinc finger, swim domain protein
BsBEST3095_37290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3095_37300	COG0561	phosphatase activity
BsBEST3095_37310	COG1349	DNA-binding transcription factor activity
BsBEST3095_37320	COG0629	single-stranded DNA binding
BsBEST3095_37350	COG3764	Sortase (surface protein transpeptidase)
BsBEST3095_37370	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_37370	COG2972	Histidine kinase
BsBEST3095_37380	COG1970	mechanosensitive ion channel activity
BsBEST3095_37390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3095_37400	COG0457	Tetratricopeptide repeat
BsBEST3095_37410	COG4786	Flagellar basal body rod
BsBEST3095_37420	COG4786	Flagellar basal body rod
BsBEST3095_37430	COG1077	Cell shape determining protein MreB Mrl
BsBEST3095_37440	COG1609	Transcriptional regulator
BsBEST3095_37450	COG1846	Transcriptional regulator
BsBEST3095_37460	COG2814	Major facilitator Superfamily
BsBEST3095_37470	COG3420	alginic acid biosynthetic process
BsBEST3095_37480	COG1953	Uracil, thiamine, allantoin
BsBEST3095_37490	COG0477	Major facilitator Superfamily
BsBEST3095_37500	COG1335	isochorismatase
BsBEST3095_37520	COG0004	ammonium transporteR
BsBEST3095_37530	COG0347	Belongs to the P(II) protein family
BsBEST3095_37540	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3095_37560	COG0789	Transcriptional regulator
BsBEST3095_37580	COG2910	NAD(P)H-binding
BsBEST3095_37590	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3095_37600	COG0804	urea catabolic process
BsBEST3095_37610	COG0832	Belongs to the urease beta subunit family
BsBEST3095_37620	COG0831	urea catabolic process
BsBEST3095_37650	COG3237	CsbD-like
BsBEST3095_37660	COG1994	Peptidase M50
BsBEST3095_37670	COG0457	Tetratricopeptide repeat
BsBEST3095_37680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BsBEST3095_37690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BsBEST3095_37710	COG2304	oxidoreductase activity
BsBEST3095_37720	COG2304	oxidoreductase activity
BsBEST3095_37740	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3095_37750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3095_37770	COG4836	Membrane
BsBEST3095_37790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BsBEST3095_37800	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BsBEST3095_37810	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BsBEST3095_37820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BsBEST3095_37830	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BsBEST3095_37840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BsBEST3095_37860	COG0356	it plays a direct role in the translocation of protons across the membrane
BsBEST3095_37880	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BsBEST3095_37890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BsBEST3095_37900	COG4475	Protein of unknown function (DUF436)
BsBEST3095_37910	COG0698	ribose 5-phosphate isomerase
BsBEST3095_37920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3095_37930	COG1971	Probably functions as a manganese efflux pump
BsBEST3095_37940	COG0009	L-threonylcarbamoyladenylate synthase
BsBEST3095_37950	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BsBEST3095_37990	COG2890	protein-(glutamine-N5) methyltransferase activity
BsBEST3095_38000	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BsBEST3095_38010	COG0346	lactoylglutathione lyase activity
BsBEST3095_38020	COG0789	Transcriptional regulator
BsBEST3095_38030	COG0679	Auxin Efflux Carrier
BsBEST3095_38040	COG0281	malic enzyme
BsBEST3095_38060	COG1435	thymidine kinase activity
BsBEST3095_38080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BsBEST3095_38090	COG1494	fructose-1,6-bisphosphatase
BsBEST3095_38100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3095_38110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BsBEST3095_38120	COG0191	fructose-bisphosphate aldolase activity
BsBEST3095_38130	COG2204	response regulator
BsBEST3095_38140	COG4821	SIS domain
BsBEST3095_38150	COG0504	CTP synthase activity
BsBEST3095_38160	COG3343	RNA polymerase activity
BsBEST3095_38170	COG1960	acyl-CoA dehydrogenase activity
BsBEST3095_38180	COG2181	nitrate reductase activity
BsBEST3095_38180	COG0247	lactate metabolic process
BsBEST3095_38190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3095_38200	COG4294	response to UV
BsBEST3095_38220	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3095_38230	COG1132	(ABC) transporter
BsBEST3095_38240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3095_38250	COG2181	nitrate reductase activity
BsBEST3095_38260	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BsBEST3095_38270	COG1140	nitrate reductase beta subunit
BsBEST3095_38280	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BsBEST3095_38290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3095_38310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3095_38320	COG2223	nitrite transmembrane transporter activity
BsBEST3095_38330	COG0018	arginyl-trna synthetase
BsBEST3095_38340	COG4506	Protein conserved in bacteria
BsBEST3095_38360	COG0535	radical SAM domain protein
BsBEST3095_38380	COG1131	(ABC) transporter
BsBEST3095_38390	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3095_38400	COG0612	Peptidase, M16
BsBEST3095_38410	COG0612	Peptidase, M16
BsBEST3095_38430	COG3391	amine dehydrogenase activity
BsBEST3095_38440	COG3391	amine dehydrogenase activity
BsBEST3095_38450	COG0457	Tetratricopeptide repeat
BsBEST3095_38470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3095_38480	COG0010	Belongs to the arginase family
BsBEST3095_38490	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BsBEST3095_38500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3095_38520	COG1994	Peptidase M50
BsBEST3095_38530	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3095_38540	COG1846	Transcriptional regulator
BsBEST3095_38550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3095_38560	COG0477	Major facilitator Superfamily
BsBEST3095_38570	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3095_38580	COG3465	dGTPase activity
BsBEST3095_38590	COG1078	dGTPase activity
BsBEST3095_38600	COG4844	belongs to the
BsBEST3095_38620	COG0697	spore germination
BsBEST3095_38630	COG0095	Lipoate-protein ligase
BsBEST3095_38640	COG0583	DNA-binding transcription factor activity
BsBEST3095_38650	COG0280	phosphate acetyltransferase
BsBEST3095_38660	COG3253	May function as heme-dependent peroxidase
BsBEST3095_38670	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_38680	COG0436	Aminotransferase
BsBEST3095_38690	COG2814	Major facilitator Superfamily
BsBEST3095_38700	COG0151	Belongs to the GarS family
BsBEST3095_38710	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_38720	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3095_38730	COG0077	Prephenate dehydratase
BsBEST3095_38740	COG2814	Major facilitator Superfamily
BsBEST3095_38750	COG0833	amino acid
BsBEST3095_38760	COG4187	Peptidase family M20/M25/M40
BsBEST3095_38770	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_38780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3095_38800	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3095_38810	COG1091	dTDP-4-dehydrorhamnose reductase activity
BsBEST3095_38820	COG1088	dTDP-glucose 4,6-dehydratase activity
BsBEST3095_38830	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BsBEST3095_38840	COG3980	spore coat polysaccharide biosynthesis protein
BsBEST3095_38850	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BsBEST3095_38860	COG2089	acid synthase
BsBEST3095_38870	COG0456	acetyltransferase
BsBEST3095_38880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3095_38890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3095_38900	COG0463	Glycosyl transferase, family 2
BsBEST3095_38920	COG2363	Small membrane protein
BsBEST3095_38930	COG2233	PERMEase
BsBEST3095_38950	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_38960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BsBEST3095_38970	COG1216	Glycosyl transferase, family 2
BsBEST3095_39000	COG1695	Transcriptional regulator
BsBEST3095_39010	COG0351	phosphomethylpyrimidine kinase
BsBEST3095_39030	COG1621	beta-fructofuranosidase activity
BsBEST3095_39040	COG1263	PTS System
BsBEST3095_39040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3095_39050	COG2116	formate transmembrane transporter activity
BsBEST3095_39060	COG3711	transcriptional antiterminator
BsBEST3095_39080	COG1404	Belongs to the peptidase S8 family
BsBEST3095_39090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3095_39100	COG0778	Nitroreductase
BsBEST3095_39110	COG0772	Belongs to the SEDS family
BsBEST3095_39130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3095_39140	COG1845	cytochrome c oxidase, subunit III
BsBEST3095_39150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3095_39160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3095_39170	COG2261	transglycosylase associated protein
BsBEST3095_39180	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BsBEST3095_39190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BsBEST3095_39200	COG2246	polysaccharide biosynthetic process
BsBEST3095_39210	COG1309	transcriptional regulator
BsBEST3095_39230	COG3162	membrane
BsBEST3095_39240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3095_39250	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3095_39260	COG2837	iron assimilation
BsBEST3095_39270	COG2822	iron ion transport
BsBEST3095_39280	COG0672	)-iron permease
BsBEST3095_39290	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3095_39300	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BsBEST3095_39310	COG0583	DNA-binding transcription factor activity
BsBEST3095_39320	COG1380	Effector of murein hydrolase LrgA
BsBEST3095_39330	COG1346	cytolysis
BsBEST3095_39340	COG2814	Major facilitator Superfamily
BsBEST3095_39350	COG4895	conserved protein (DUF2196)
BsBEST3095_39360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BsBEST3095_39370	COG0346	lactoylglutathione lyase activity
BsBEST3095_39390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3095_39400	COG1404	Belongs to the peptidase S8 family
BsBEST3095_39410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3095_39410	COG1263	PTS System
BsBEST3095_39420	COG3711	transcriptional antiterminator
BsBEST3095_39430	COG1442	glycosyl transferase family 8
BsBEST3095_39440	COG5522	Integral membrane protein (intg_mem_TP0381)
BsBEST3095_39450	COG1846	Transcriptional regulator
BsBEST3095_39460	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3095_39470	COG2234	aminopeptidase activity
BsBEST3095_39480	COG2357	RelA SpoT domain protein
BsBEST3095_39490	COG1575	Belongs to the MenA family. Type 1 subfamily
BsBEST3095_39500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3095_39510	COG1696	Membrane protein involved in D-alanine export
BsBEST3095_39520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3095_39530	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BsBEST3095_39540	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3095_39550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3095_39560	COG1486	melibiose metabolic process
BsBEST3095_39570	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3095_39580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3095_39590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3095_39600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3095_39600	COG3711	transcriptional antiterminator
BsBEST3095_39620	COG2094	Belongs to the DNA glycosylase MPG family
BsBEST3095_39630	COG0753	catalase activity
BsBEST3095_39640	COG2814	Major facilitator Superfamily
BsBEST3095_39650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3095_39660	COG1131	(ABC) transporter
BsBEST3095_39700	COG1595	DNA-templated transcription, initiation
BsBEST3095_39710	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3095_39720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BsBEST3095_39730	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BsBEST3095_39740	COG4988	ABC transporter
BsBEST3095_39750	COG1294	oxidase, subunit
BsBEST3095_39760	COG1271	oxidase subunit
BsBEST3095_39770	COG3493	citrate carrier protein
BsBEST3095_39780	COG0501	Belongs to the peptidase M48B family
BsBEST3095_39800	COG0726	polysaccharide deacetylase
BsBEST3095_39810	COG3842	ATPase activity
BsBEST3095_39820	COG2508	Transcriptional regulator
BsBEST3095_39830	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_39840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3095_39860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BsBEST3095_39870	COG1881	PFAM PEBP family protein
BsBEST3095_39880	COG0583	DNA-binding transcription factor activity
BsBEST3095_39900	COG4585	Histidine kinase
BsBEST3095_39910	COG2197	response regulator
BsBEST3095_39920	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3095_39940	COG4894	glucomannan catabolic process
BsBEST3095_39950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3095_39960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3095_39970	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_39980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3095_39990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3095_40000	COG2610	gluconate transmembrane transporter activity
BsBEST3095_40010	COG0500	methyltransferase
BsBEST3095_40020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3095_40060	COG0693	protein deglycase activity
BsBEST3095_40060	COG0753	catalase activity
BsBEST3095_40070	COG2851	Citrate transporter
BsBEST3095_40080	COG2273	Hydrolase Family 16
BsBEST3095_40090	COG3711	transcriptional antiterminator
BsBEST3095_40110	COG2270	Major facilitator Superfamily
BsBEST3095_40120	COG0513	Belongs to the DEAD box helicase family
BsBEST3095_40130	COG2755	lipolytic protein G-D-S-L family
BsBEST3095_40130	COG3401	FG-GAP repeat protein
BsBEST3095_40250	COG3209	COG3209 Rhs family protein
BsBEST3095_40270	COG0697	spore germination
BsBEST3095_40280	COG0589	response to stress
BsBEST3095_40290	COG2723	6-phospho-beta-galactosidase activity
BsBEST3095_40300	COG1263	PTS System
BsBEST3095_40300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3095_40300	COG2190	(PTS) system
BsBEST3095_40330	COG5444	nuclease activity
BsBEST3095_40360	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3095_40390	COG2986	histidine ammonia-lyase
BsBEST3095_40400	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BsBEST3095_40410	COG1228	amidohydrolase
BsBEST3095_40420	COG0010	Belongs to the arginase family
BsBEST3095_40430	COG0833	amino acid
BsBEST3095_40440	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BsBEST3095_40450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3095_40460	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BsBEST3095_40470	COG2390	Transcriptional regulator
BsBEST3095_40490	COG3192	ethanolamine utilization protein
BsBEST3095_40500	COG2079	MmgE PrpD family protein
BsBEST3095_40510	COG1473	amidohydrolase
BsBEST3095_40520	COG1126	abc transporter atp-binding protein
BsBEST3095_40530	COG0765	amino acid transport
BsBEST3095_40540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3095_40550	COG0456	acetyltransferase
BsBEST3095_40560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3095_40580	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BsBEST3095_40590	COG0561	phosphatase activity
BsBEST3095_40650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3095_40660	COG5294	Protein conserved in bacteria
BsBEST3095_40670	COG0577	efflux transmembrane transporter activity
BsBEST3095_40680	COG1136	(ABC) transporter
BsBEST3095_40690	COG2205	protein histidine kinase activity
BsBEST3095_40700	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_40710	COG0191	fructose-bisphosphate aldolase activity
BsBEST3095_40720	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3095_40730	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3095_40740	COG0673	inositol 2-dehydrogenase activity
BsBEST3095_40750	COG2814	Major facilitator Superfamily
BsBEST3095_40760	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3095_40770	COG3962	Belongs to the TPP enzyme family
BsBEST3095_40780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3095_40790	COG3718	enzyme involved in inositol metabolism
BsBEST3095_40800	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_40810	COG1349	DNA-binding transcription factor activity
BsBEST3095_40820	COG0667	Aldo Keto reductase
BsBEST3095_40850	COG2814	Major facilitator Superfamily
BsBEST3095_40860	COG0326	Molecular chaperone. Has ATPase activity
BsBEST3095_40880	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_40890	COG1309	transcriptional regulator
BsBEST3095_40900	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3095_40910	COG0456	acetyltransferase
BsBEST3095_40920	COG2850	peptidyl-arginine hydroxylation
BsBEST3095_40930	COG2226	methyltransferase
BsBEST3095_40960	COG0367	asparagine synthase
BsBEST3095_40970	COG2814	Major facilitator Superfamily
BsBEST3095_40980	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BsBEST3095_41000	COG1714	RDD family
BsBEST3095_41010	COG2311	Membrane
BsBEST3095_41020	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3095_41030	COG1309	transcriptional regulator
BsBEST3095_41040	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3095_41050	COG1846	Transcriptional regulator
BsBEST3095_41060	COG1380	Effector of murein hydrolase LrgA
BsBEST3095_41070	COG1346	cytolysis
BsBEST3095_41080	COG5039	Polysaccharide pyruvyl transferase
BsBEST3095_41090	COG1929	Belongs to the glycerate kinase type-1 family
BsBEST3095_41100	COG1802	Transcriptional regulator
BsBEST3095_41110	COG1070	Carbohydrate kinase
BsBEST3095_41120	COG2610	gluconate transmembrane transporter activity
BsBEST3095_41130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3095_41140	COG0450	alkyl hydroperoxide reductase
BsBEST3095_41150	COG3634	alkyl hydroperoxide reductase activity
BsBEST3095_41160	COG2723	6-phospho-beta-galactosidase activity
BsBEST3095_41170	COG2190	(PTS) system
BsBEST3095_41180	COG2188	Transcriptional regulator
BsBEST3095_41210	COG1131	(ABC) transporter
BsBEST3095_41220	COG1994	Peptidase M50
BsBEST3095_41230	COG0535	radical SAM domain protein
BsBEST3095_41250	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BsBEST3095_41260	COG5293	efflux transmembrane transporter activity
BsBEST3095_41280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3095_41290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BsBEST3095_41320	COG1063	alcohol dehydrogenase
BsBEST3095_41360	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BsBEST3095_41370	COG0456	acetyltransferase
BsBEST3095_41380	COG0457	Tetratricopeptide repeat
BsBEST3095_41390	COG0010	Belongs to the arginase family
BsBEST3095_41400	COG0833	amino acid
BsBEST3095_41410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3095_41420	COG3829	transcription factor binding
BsBEST3095_41430	COG5002	protein histidine kinase activity
BsBEST3095_41450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3095_41460	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BsBEST3095_41470	COG4853	Protein conserved in bacteria
BsBEST3095_41480	COG4863	YycH protein
BsBEST3095_41490	COG5002	protein histidine kinase activity
BsBEST3095_41500	COG0745	RESPONSE REGULATOR receiver
BsBEST3095_41520	COG0346	lactoylglutathione lyase activity
BsBEST3095_41530	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3095_41560	COG3093	addiction module antidote protein HigA
BsBEST3095_41570	COG2807	transmembrane transport
BsBEST3095_41580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3095_41590	COG0359	binds to the 23S rRNA
BsBEST3095_41600	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BsBEST3095_41610	COG4241	membrane
BsBEST3095_41630	COG5577	PFAM Coat F domain
BsBEST3095_41640	COG1733	regulation of RNA biosynthetic process
BsBEST3095_41650	COG1227	inorganic diphosphatase activity
BsBEST3095_41680	COG2271	Major facilitator Superfamily
BsBEST3095_41750	COG1131	(ABC) transporter
BsBEST3095_41770	COG4319	ketosteroid isomerase
BsBEST3095_41780	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3095_41790	COG2814	Major facilitator Superfamily
BsBEST3095_41800	COG0583	DNA-binding transcription factor activity
BsBEST3095_41810	COG2153	protein acetylation
BsBEST3095_41830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3095_41840	COG1846	Transcriptional regulator
BsBEST3095_41850	COG2153	protein acetylation
BsBEST3095_41860	COG2364	Membrane
BsBEST3095_41870	COG0456	acetyltransferase
BsBEST3095_41880	COG2315	Protein conserved in bacteria
BsBEST3095_41890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3095_41900	COG2814	Major facilitator Superfamily
BsBEST3095_41910	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3095_41920	COG0789	Transcriptional regulator
BsBEST3095_41930	COG0697	spore germination
BsBEST3095_41940	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3095_41950	COG1266	CAAX protease self-immunity
BsBEST3095_41960	COG0477	Major facilitator Superfamily
BsBEST3095_41960	COG2814	Major facilitator Superfamily
BsBEST3095_41970	COG0110	maltose O-acetyltransferase activity
BsBEST3095_41980	COG0346	lactoylglutathione lyase activity
BsBEST3095_41990	COG1609	Transcriptional regulator
BsBEST3095_42000	COG0708	Exodeoxyribonuclease III
BsBEST3095_42010	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BsBEST3095_42020	COG0629	single-stranded DNA binding
BsBEST3095_42030	COG0360	Binds together with S18 to 16S ribosomal RNA
BsBEST3095_42040	COG0012	GTP binding
BsBEST3095_42050	COG0243	molybdopterin cofactor binding
BsBEST3095_42060	COG4481	Protein conserved in bacteria
BsBEST3095_42070	COG3949	Membrane
BsBEST3095_42090	COG1475	DNA binding
BsBEST3095_42100	COG1192	Involved in chromosome partitioning
BsBEST3095_42120	COG1475	DNA binding
BsBEST3095_42130	COG0357	Ribosomal RNA small subunit methyltransferase G
BsBEST3095_42140	COG0445	tRNA wobble uridine modification
BsBEST3095_42150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BsBEST3095_42160	COG1847	R3H domain protein
BsBEST3095_42170	COG0706	membrane insertase activity
BsBEST3095_42180	COG0594	ribonuclease P activity