locus-tag	class	description
BsBEST3096_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BsBEST3096_00020	COG0592	DNA-directed DNA polymerase activity
BsBEST3096_00030	COG2501	S4 domain
BsBEST3096_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BsBEST3096_00060	COG0187	DNA topoisomerase II activity
BsBEST3096_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3096_00090	COG0516	GMP reductase activity
BsBEST3096_00090	COG0517	IMP dehydrogenase activity
BsBEST3096_00100	COG1686	Belongs to the peptidase S11 family
BsBEST3096_00110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BsBEST3096_00120	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BsBEST3096_00130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BsBEST3096_00140	COG1428	Deoxynucleoside kinase
BsBEST3096_00150	COG1428	Deoxynucleoside kinase
BsBEST3096_00160	COG1388	LysM domain
BsBEST3096_00160	COG3858	chitin binding
BsBEST3096_00170	COG1335	isochorismatase
BsBEST3096_00180	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3096_00190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BsBEST3096_00200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BsBEST3096_00210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BsBEST3096_00250	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BsBEST3096_00260	COG3853	Toxic anion resistance protein (TelA)
BsBEST3096_00270	COG1982	Orn Lys Arg decarboxylase major
BsBEST3096_00280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3096_00290	COG3870	Protein conserved in bacteria
BsBEST3096_00300	COG1728	Protein conserved in bacteria
BsBEST3096_00310	COG0470	DNA polymerase III
BsBEST3096_00320	COG1774	PSP1 C-terminal conserved region
BsBEST3096_00330	COG4467	Involved in initiation control of chromosome replication
BsBEST3096_00340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BsBEST3096_00350	COG2827	Endonuclease containing a URI domain
BsBEST3096_00360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BsBEST3096_00370	COG2002	toxin-antitoxin pair type II binding
BsBEST3096_00380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3096_00380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3096_00390	COG0084	hydrolase, TatD family'
BsBEST3096_00400	COG3584	3D domain protein
BsBEST3096_00400	COG3583	domain protein
BsBEST3096_00410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3096_00420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BsBEST3096_00440	COG4466	Protein conserved in bacteria
BsBEST3096_00460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BsBEST3096_00470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3096_00480	COG0251	oxidation-reduction process
BsBEST3096_00490	COG2088	sporulation resulting in formation of a cellular spore
BsBEST3096_00500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BsBEST3096_00510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BsBEST3096_00520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BsBEST3096_00530	COG0193	aminoacyl-tRNA hydrolase activity
BsBEST3096_00550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BsBEST3096_00560	COG2002	toxin-antitoxin pair type II binding
BsBEST3096_00570	COG2244	polysaccharide biosynthetic process
BsBEST3096_00580	COG3956	TIGRFAM MazG family protein
BsBEST3096_00590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BsBEST3096_00620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BsBEST3096_00630	COG1098	S1 RNA binding domain
BsBEST3096_00640	COG2208	phosphoserine phosphatase activity
BsBEST3096_00650	COG2304	oxidoreductase activity
BsBEST3096_00660	COG0515	serine threonine protein kinase
BsBEST3096_00670	COG0037	tRNA processing
BsBEST3096_00680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BsBEST3096_00690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3096_00700	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BsBEST3096_00710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BsBEST3096_00720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3096_00730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3096_00740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3096_00750	COG0512	Glutamine amidotransferase of anthranilate synthase
BsBEST3096_00760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3096_00770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BsBEST3096_00780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BsBEST3096_00790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BsBEST3096_00800	COG1396	sequence-specific DNA binding
BsBEST3096_00810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3096_00820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BsBEST3096_00830	COG4463	regulation of RNA biosynthetic process
BsBEST3096_00840	COG3880	PFAM UvrB UvrC protein
BsBEST3096_00850	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BsBEST3096_00860	COG0542	response to heat
BsBEST3096_00870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BsBEST3096_00880	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BsBEST3096_00890	COG4956	integral membrane protein (PIN domain superfamily)
BsBEST3096_00900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BsBEST3096_00910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BsBEST3096_00920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BsBEST3096_00930	COG1045	serine acetyltransferase
BsBEST3096_00940	COG0215	cysteine-tRNA ligase activity
BsBEST3096_00950	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BsBEST3096_00960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3096_00970	COG3688	RNA-binding protein containing a PIN domain
BsBEST3096_00980	COG1595	DNA-templated transcription, initiation
BsBEST3096_00990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3096_01000	COG0250	Participates in transcription elongation, termination and antitermination
BsBEST3096_01020	COG0081	regulation of translation
BsBEST3096_01030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BsBEST3096_01050	COG2813	Specifically methylates the guanine in position
BsBEST3096_01060	COG0085	RNA polymerase activity
BsBEST3096_01070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BsBEST3096_01080	COG1358	cellular component organization or biogenesis
BsBEST3096_01090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BsBEST3096_01100	COG0049	tRNA binding
BsBEST3096_01110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BsBEST3096_01120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BsBEST3096_01130	COG0596	Alpha beta hydrolase
BsBEST3096_01150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BsBEST3096_01160	COG0088	Forms part of the polypeptide exit tunnel
BsBEST3096_01180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BsBEST3096_01210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BsBEST3096_01220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BsBEST3096_01240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BsBEST3096_01250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BsBEST3096_01270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BsBEST3096_01290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BsBEST3096_01300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BsBEST3096_01310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BsBEST3096_01340	COG0200	Binds to the 23S rRNA
BsBEST3096_01350	COG0201	protein transport
BsBEST3096_01360	COG0563	adenylate kinase activity
BsBEST3096_01370	COG0024	Methionine aminopeptidase
BsBEST3096_01390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BsBEST3096_01400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BsBEST3096_01410	COG0202	RNA polymerase activity
BsBEST3096_01420	COG0203	ribosomal protein L17
BsBEST3096_01430	COG1122	ATPase activity
BsBEST3096_01440	COG1122	ATPase activity
BsBEST3096_01450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3096_01460	COG0101	tRNA pseudouridine synthase activity
BsBEST3096_01470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BsBEST3096_01480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BsBEST3096_01490	COG2226	methyltransferase
BsBEST3096_01510	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_01520	COG0489	protein tyrosine kinase activity
BsBEST3096_01540	COG2194	sulfuric ester hydrolase activity
BsBEST3096_01550	COG0726	polysaccharide deacetylase
BsBEST3096_01560	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3096_01580	COG0385	Bile acid
BsBEST3096_01590	COG2819	hydrolase of the alpha beta superfamily
BsBEST3096_01600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3096_01610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3096_01620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3096_01630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3096_01630	COG2207	Transcriptional regulator
BsBEST3096_01640	COG3876	Protein conserved in bacteria
BsBEST3096_01650	COG1472	Belongs to the glycosyl hydrolase 3 family
BsBEST3096_01660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3096_01670	COG1263	PTS System
BsBEST3096_01670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3096_01680	COG1737	Transcriptional regulator
BsBEST3096_01690	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BsBEST3096_01700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3096_01710	COG1683	Conserved Protein
BsBEST3096_01720	COG1595	DNA-templated transcription, initiation
BsBEST3096_01730	COG5662	AntiSigma factor
BsBEST3096_01740	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3096_01750	COG4856	YbbR-like protein
BsBEST3096_01760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3096_01770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BsBEST3096_01790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3096_01800	COG2169	Transcriptional regulator
BsBEST3096_01810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3096_01820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3096_01830	COG3002	Belongs to the UPF0753 family
BsBEST3096_01840	COG0288	reversible hydration of carbon dioxide
BsBEST3096_01860	COG5609	conserved protein (DUF2294)
BsBEST3096_01880	COG0640	Transcriptional regulator
BsBEST3096_01890	COG2814	Major facilitator Superfamily
BsBEST3096_01900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BsBEST3096_01920	COG0535	radical SAM domain protein
BsBEST3096_01930	COG1266	CAAX protease self-immunity
BsBEST3096_01940	COG1131	(ABC) transporter
BsBEST3096_01960	COG1413	lyase activity
BsBEST3096_01970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_01980	COG0596	Alpha beta hydrolase
BsBEST3096_01990	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_02000	COG0642	Histidine kinase
BsBEST3096_02020	COG0515	serine threonine protein kinase
BsBEST3096_02050	COG1113	amino acid transport
BsBEST3096_02080	COG2602	Beta-lactamase
BsBEST3096_02090	COG2124	cytochrome p450
BsBEST3096_02110	COG0531	amino acid
BsBEST3096_02120	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3096_02130	COG2271	Major facilitator Superfamily
BsBEST3096_02150	COG0456	acetyltransferase
BsBEST3096_02150	COG1846	Transcriptional regulator
BsBEST3096_02160	COG2271	Major facilitator Superfamily
BsBEST3096_02190	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_02200	COG0697	spore germination
BsBEST3096_02210	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3096_02210	COG2207	Transcriptional regulator
BsBEST3096_02220	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BsBEST3096_02230	COG3591	Belongs to the peptidase S1B family
BsBEST3096_02250	COG0596	Alpha beta hydrolase
BsBEST3096_02260	COG1183	phosphatidylcholine synthase activity
BsBEST3096_02270	COG0586	Pfam SNARE associated Golgi protein
BsBEST3096_02280	COG0688	phosphatidylethanolamine metabolic process
BsBEST3096_02300	COG2312	Erythromycin esterase
BsBEST3096_02310	COG2207	Transcriptional regulator
BsBEST3096_02320	COG1054	Belongs to the UPF0176 family
BsBEST3096_02330	COG1301	dicarboxylic acid transport
BsBEST3096_02340	COG1263	PTS System
BsBEST3096_02340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3096_02340	COG2190	(PTS) system
BsBEST3096_02350	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3096_02360	COG2188	Transcriptional regulator
BsBEST3096_02380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3096_02390	COG0833	amino acid
BsBEST3096_02400	COG2040	homocysteine
BsBEST3096_02410	COG1115	amino acid carrier protein
BsBEST3096_02420	COG2066	Belongs to the glutaminase family
BsBEST3096_02430	COG4191	Histidine kinase
BsBEST3096_02440	COG0784	Response regulator, receiver
BsBEST3096_02450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3096_02460	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_02470	COG2271	Major facilitator Superfamily
BsBEST3096_02480	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3096_02490	COG2186	Transcriptional regulator
BsBEST3096_02500	COG2721	sulfolactate sulfo-lyase activity
BsBEST3096_02510	COG3173	Aminoglycoside phosphotransferase
BsBEST3096_02530	COG0697	spore germination
BsBEST3096_02540	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_02550	COG2205	protein histidine kinase activity
BsBEST3096_02560	COG1131	(ABC) transporter
BsBEST3096_02590	COG3773	Cell wall hydrolase
BsBEST3096_02600	COG2304	oxidoreductase activity
BsBEST3096_02610	COG3540	Alkaline phosphatase
BsBEST3096_02620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3096_02630	COG0805	protein transport
BsBEST3096_02640	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BsBEST3096_02650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3096_02660	COG0477	Major facilitator Superfamily
BsBEST3096_02670	COG1309	transcriptional regulator
BsBEST3096_02680	COG0252	asparaginase activity
BsBEST3096_02690	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3096_02700	COG1714	RDD family
BsBEST3096_02710	COG1405	negative regulation of cell septum assembly
BsBEST3096_02710	COG3012	SEC-C Motif Domain Protein
BsBEST3096_02720	COG3290	protein histidine kinase activity
BsBEST3096_02730	COG3279	Response regulator of the LytR AlgR family
BsBEST3096_02740	COG4555	ABC transporter
BsBEST3096_02750	COG1668	transmembrane transport
BsBEST3096_02760	COG0667	Aldo Keto reductase
BsBEST3096_02780	COG1595	DNA-templated transcription, initiation
BsBEST3096_02790	COG1595	DNA-templated transcription, initiation
BsBEST3096_02800	COG1876	peptidase activity
BsBEST3096_02810	COG0457	Tetratricopeptide repeat
BsBEST3096_02820	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_02830	COG0366	Alpha amylase catalytic
BsBEST3096_02840	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3096_02850	COG1121	(ABC) transporter
BsBEST3096_02860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3096_02870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3096_02880	COG2310	stress, protein
BsBEST3096_02890	COG2310	stress, protein
BsBEST3096_02900	COG2310	stress, protein
BsBEST3096_02910	COG0861	Integral membrane protein TerC family
BsBEST3096_02930	COG3853	Toxic anion resistance protein (TelA)
BsBEST3096_02940	COG0477	Major facilitator Superfamily
BsBEST3096_02950	COG2814	Major facilitator Superfamily
BsBEST3096_02960	COG0640	Transcriptional regulator
BsBEST3096_02970	COG0517	IMP dehydrogenase activity
BsBEST3096_02970	COG4175	Glycine betaine
BsBEST3096_02980	COG4176	ABC-type proline glycine betaine transport system permease component
BsBEST3096_02990	COG2113	Glycine betaine
BsBEST3096_03000	COG1473	amidohydrolase
BsBEST3096_03010	COG1288	antiporter activity
BsBEST3096_03030	COG0366	Alpha amylase catalytic
BsBEST3096_03040	COG0039	L-malate dehydrogenase activity
BsBEST3096_03050	COG1620	l-lactate permease
BsBEST3096_03060	COG2814	Major facilitator Superfamily
BsBEST3096_03070	COG1846	Transcriptional regulator
BsBEST3096_03080	COG1280	lysine exporter protein (LysE YggA)
BsBEST3096_03090	COG3403	YqcI/YcgG family
BsBEST3096_03100	COG1113	amino acid transport
BsBEST3096_03110	COG3665	Urea carboxylase-associated protein
BsBEST3096_03120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BsBEST3096_03130	COG1660	Displays ATPase and GTPase activities
BsBEST3096_03140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BsBEST3096_03150	COG2226	methyltransferase
BsBEST3096_03160	COG0583	DNA-binding transcription factor activity
BsBEST3096_03170	COG3458	cephalosporin-C deacetylase activity
BsBEST3096_03180	COG3541	Predicted nucleotidyltransferase
BsBEST3096_03190	COG0506	proline dehydrogenase activity
BsBEST3096_03200	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_03210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3096_03220	COG2508	Transcriptional regulator
BsBEST3096_03230	COG3689	TIGRFAM TIGR03943 family protein
BsBEST3096_03240	COG0701	Predicted permease
BsBEST3096_03250	COG2267	carboxylic ester hydrolase activity
BsBEST3096_03260	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3096_03270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3096_03270	COG1587	Uroporphyrinogen-III synthase
BsBEST3096_03280	COG2146	nitrite reductase [NAD(P)H] activity
BsBEST3096_03290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3096_03300	COG0243	molybdopterin cofactor binding
BsBEST3096_03310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3096_03320	COG2223	nitrite transmembrane transporter activity
BsBEST3096_03330	COG1469	GTP cyclohydrolase I activity
BsBEST3096_03340	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3096_03350	COG0523	cobalamin synthesis protein
BsBEST3096_03360	COG0765	amino acid transport
BsBEST3096_03370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3096_03390	COG1714	RDD family
BsBEST3096_03410	COG2723	6-phospho-beta-galactosidase activity
BsBEST3096_03430	COG3209	COG3209 Rhs family protein
BsBEST3096_03440	COG3290	protein histidine kinase activity
BsBEST3096_03440	COG0840	transmembrane signaling receptor activity
BsBEST3096_03450	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BsBEST3096_03460	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BsBEST3096_03470	COG1733	regulation of RNA biosynthetic process
BsBEST3096_03480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_03490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_03500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_03510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_03520	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BsBEST3096_03530	COG2814	Major facilitator Superfamily
BsBEST3096_03550	COG0697	spore germination
BsBEST3096_03560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3096_03590	COG2364	Membrane
BsBEST3096_03600	COG1126	abc transporter atp-binding protein
BsBEST3096_03610	COG0765	amino acid transport
BsBEST3096_03620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3096_03630	COG0583	DNA-binding transcription factor activity
BsBEST3096_03640	COG0163	prenyltransferase activity
BsBEST3096_03650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BsBEST3096_03680	COG0596	Alpha beta hydrolase
BsBEST3096_03690	COG3104	oligopeptide transport
BsBEST3096_03700	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3096_03720	COG0697	spore germination
BsBEST3096_03740	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3096_03750	COG1136	(ABC) transporter
BsBEST3096_03760	COG0577	efflux transmembrane transporter activity
BsBEST3096_03770	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_03780	COG5002	protein histidine kinase activity
BsBEST3096_03780	COG3850	Histidine kinase
BsBEST3096_03790	COG0457	Tetratricopeptide repeat
BsBEST3096_03810	COG0527	aspartate kinase activity
BsBEST3096_03820	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3096_03830	COG4605	iron ion homeostasis
BsBEST3096_03840	COG4604	ABC transporter, ATP-binding protein
BsBEST3096_03850	COG4607	ABC-type enterochelin transport system periplasmic component
BsBEST3096_03860	COG2814	Major facilitator Superfamily
BsBEST3096_03870	COG1309	transcriptional regulator
BsBEST3096_03880	COG0778	Nitroreductase
BsBEST3096_03890	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3096_03900	COG0640	Transcriptional regulator
BsBEST3096_03910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3096_03920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BsBEST3096_03930	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_03940	COG4975	Glucose uptake
BsBEST3096_03950	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_03960	COG4549	nuclear export factor GLE1
BsBEST3096_03970	COG1276	copper resistance
BsBEST3096_03970	COG2372	response to copper ion
BsBEST3096_03980	COG1349	DNA-binding transcription factor activity
BsBEST3096_04000	COG2213	PTS system mannitol-specific
BsBEST3096_04010	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3096_04020	COG0246	Mannitol dehydrogenase
BsBEST3096_04030	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3096_04050	COG0681	Belongs to the peptidase S26 family
BsBEST3096_04060	COG0412	Dienelactone hydrolase
BsBEST3096_04070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3096_04090	COG0561	phosphatase activity
BsBEST3096_04100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3096_04110	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3096_04120	COG4336	lyase activity
BsBEST3096_04130	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3096_04140	COG1984	allophanate hydrolase subunit 2
BsBEST3096_04150	COG1414	Transcriptional regulator
BsBEST3096_04160	COG2755	lipolytic protein G-D-S-L family
BsBEST3096_04180	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3096_04190	COG0768	penicillin binding
BsBEST3096_04200	COG4989	oxidoreductase activity
BsBEST3096_04210	COG3711	transcriptional antiterminator
BsBEST3096_04220	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3096_04230	COG2226	methyltransferase
BsBEST3096_04240	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_04250	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3096_04260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3096_04270	COG3871	stress protein (general stress protein 26)
BsBEST3096_04290	COG2814	Major facilitator Superfamily
BsBEST3096_04300	COG1522	sequence-specific DNA binding
BsBEST3096_04310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3096_04310	COG0551	DNA topoisomerase type I activity
BsBEST3096_04320	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BsBEST3096_04330	COG3706	GGDEF domain
BsBEST3096_04340	COG5298	Protein conserved in bacteria
BsBEST3096_04350	COG1215	transferase activity, transferring glycosyl groups
BsBEST3096_04370	COG0531	amino acid
BsBEST3096_04380	COG0494	nUDIX hydrolase
BsBEST3096_04390	COG0028	Belongs to the TPP enzyme family
BsBEST3096_04420	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3096_04430	COG2261	transglycosylase associated protein
BsBEST3096_04440	COG4876	unkown
BsBEST3096_04450	COG2217	Heavy metal translocating P-type atpase
BsBEST3096_04460	COG3729	General stress protein
BsBEST3096_04470	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3096_04480	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3096_04490	COG3546	catalase activity
BsBEST3096_04500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BsBEST3096_04510	COG3290	protein histidine kinase activity
BsBEST3096_04520	COG4565	transcriptional regulatory protein
BsBEST3096_04530	COG1301	dicarboxylic acid transport
BsBEST3096_04540	COG0628	permease
BsBEST3096_04560	COG1131	(ABC) transporter
BsBEST3096_04570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3096_04590	COG1960	acyl-CoA dehydrogenase activity
BsBEST3096_04620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3096_04630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_04640	COG1181	Belongs to the D-alanine--D-alanine ligase family
BsBEST3096_04650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BsBEST3096_04660	COG0513	Belongs to the DEAD box helicase family
BsBEST3096_04670	COG3402	PFAM membrane-flanked domain
BsBEST3096_04680	COG3428	Bacterial PH domain
BsBEST3096_04690	COG0705	Rhomboid family
BsBEST3096_04700	COG0736	holo-[acyl-carrier-protein] synthase activity
BsBEST3096_04710	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BsBEST3096_04720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3096_04730	COG0864	Transcriptional regulator
BsBEST3096_04740	COG2337	Toxic component of a toxin-antitoxin (TA) module
BsBEST3096_04750	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3096_04760	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3096_04770	COG2172	sigma factor antagonist activity
BsBEST3096_04780	COG2208	phosphoserine phosphatase activity
BsBEST3096_04790	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3096_04800	COG2172	sigma factor antagonist activity
BsBEST3096_04810	COG1191	sigma factor activity
BsBEST3096_04820	COG2208	phosphoserine phosphatase activity
BsBEST3096_04850	COG1673	EVE domain
BsBEST3096_04860	COG1846	Transcriptional regulator
BsBEST3096_04870	COG2183	response to ionizing radiation
BsBEST3096_04880	COG3091	SprT-like family
BsBEST3096_04890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3096_04900	COG1522	sequence-specific DNA binding
BsBEST3096_04910	COG1522	sequence-specific DNA binding
BsBEST3096_04920	COG1335	isochorismatase
BsBEST3096_04930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3096_04940	COG2814	Major facilitator Superfamily
BsBEST3096_04980	COG0693	protein deglycase activity
BsBEST3096_04990	COG1278	Cold shock
BsBEST3096_05000	COG1329	Transcriptional regulator
BsBEST3096_05010	COG0697	spore germination
BsBEST3096_05020	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3096_05020	COG2207	Transcriptional regulator
BsBEST3096_05030	COG0697	spore germination
BsBEST3096_05040	COG2207	Transcriptional regulator
BsBEST3096_05040	COG3708	Transcriptional regulator
BsBEST3096_05050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3096_05060	COG0477	Major facilitator Superfamily
BsBEST3096_05080	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BsBEST3096_05100	COG0697	spore germination
BsBEST3096_05110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3096_05120	COG2030	dehydratase
BsBEST3096_05130	COG3545	Serine hydrolase
BsBEST3096_05140	COG1733	regulation of RNA biosynthetic process
BsBEST3096_05150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3096_05160	COG1733	regulation of RNA biosynthetic process
BsBEST3096_05170	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3096_05180	COG2814	Major facilitator Superfamily
BsBEST3096_05190	COG1309	transcriptional regulator
BsBEST3096_05210	COG0640	Transcriptional regulator
BsBEST3096_05220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3096_05230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3096_05240	COG0697	spore germination
BsBEST3096_05250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3096_05260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3096_05270	COG0640	Transcriptional regulator
BsBEST3096_05280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3096_05300	COG4585	Histidine kinase
BsBEST3096_05310	COG2197	response regulator
BsBEST3096_05320	COG2409	Drug exporters of the RND superfamily
BsBEST3096_05330	COG0596	Alpha beta hydrolase
BsBEST3096_05340	COG1811	Na channel or pump
BsBEST3096_05350	COG0789	Transcriptional regulator
BsBEST3096_05350	COG4978	Transcriptional regulator
BsBEST3096_05360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3096_05370	COG0778	Nitroreductase
BsBEST3096_05380	COG0346	lactoylglutathione lyase activity
BsBEST3096_05390	COG2259	Doxx family
BsBEST3096_05400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_05430	COG2323	membrane
BsBEST3096_05440	COG2323	membrane
BsBEST3096_05450	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3096_05480	COG1309	transcriptional regulator
BsBEST3096_05500	COG0456	acetyltransferase
BsBEST3096_05510	COG0488	(ABC) transporter
BsBEST3096_05520	COG1113	amino acid transport
BsBEST3096_05530	COG2318	DinB family
BsBEST3096_05540	COG1846	Transcriptional regulator
BsBEST3096_05550	COG1033	growth of symbiont in host cell
BsBEST3096_05550	COG2409	Drug exporters of the RND superfamily
BsBEST3096_05560	COG0778	Nitroreductase
BsBEST3096_05570	COG1846	Transcriptional regulator
BsBEST3096_05580	COG2814	Major facilitator Superfamily
BsBEST3096_05590	COG0730	response to heat
BsBEST3096_05600	COG1802	Transcriptional regulator
BsBEST3096_05610	COG1388	LysM domain
BsBEST3096_05610	COG3858	chitin binding
BsBEST3096_05620	COG1819	glycosyl
BsBEST3096_05640	COG1785	Belongs to the alkaline phosphatase family
BsBEST3096_05650	COG5646	InterPro IPR014922
BsBEST3096_05670	COG0454	-acetyltransferase
BsBEST3096_05680	COG1078	dGTPase activity
BsBEST3096_05690	COG1388	LysM domain
BsBEST3096_05700	COG2814	Major facilitator Superfamily
BsBEST3096_05710	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3096_05720	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3096_05730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3096_05740	COG2723	6-phospho-beta-galactosidase activity
BsBEST3096_05750	COG2188	Transcriptional regulator
BsBEST3096_05760	COG1940	carbohydrate kinase activity
BsBEST3096_05770	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3096_05780	COG4124	Belongs to the glycosyl hydrolase 26 family
BsBEST3096_05810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BsBEST3096_05820	COG0802	atpase or kinase
BsBEST3096_05830	COG1214	PFAM Peptidase M22, glycoprotease
BsBEST3096_05840	COG0456	acetyltransferase
BsBEST3096_05850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BsBEST3096_05860	COG0488	(ABC) transporter
BsBEST3096_05870	COG0315	cyclic pyranopterin monophosphate synthase activity
BsBEST3096_05880	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BsBEST3096_05890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3096_05900	COG0805	protein transport
BsBEST3096_05920	COG1266	CAAX protease self-immunity
BsBEST3096_05940	COG0459	protein refolding
BsBEST3096_05970	COG3378	Phage plasmid primase P4 family
BsBEST3096_06000	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3096_06010	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3096_06040	COG1401	restriction endodeoxyribonuclease activity
BsBEST3096_06090	COG1073	alpha beta
BsBEST3096_06100	COG0457	Tetratricopeptide repeat
BsBEST3096_06110	COG1063	alcohol dehydrogenase
BsBEST3096_06120	COG2211	Major facilitator Superfamily
BsBEST3096_06130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3096_06140	COG1842	Phage shock protein A
BsBEST3096_06150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3096_06160	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BsBEST3096_06170	COG4260	virion core protein, lumpy skin disease virus
BsBEST3096_06190	COG2814	Major facilitator Superfamily
BsBEST3096_06200	COG1063	alcohol dehydrogenase
BsBEST3096_06210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BsBEST3096_06220	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3096_06250	COG2267	carboxylic ester hydrolase activity
BsBEST3096_06270	COG2132	Multicopper oxidase
BsBEST3096_06280	COG1113	amino acid transport
BsBEST3096_06290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3096_06300	COG0714	Associated with various cellular activities
BsBEST3096_06310	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BsBEST3096_06320	COG1305	Transglutaminase-like
BsBEST3096_06330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BsBEST3096_06330	COG0519	Catalyzes the synthesis of GMP from XMP
BsBEST3096_06340	COG2252	PERMEase
BsBEST3096_06350	COG3064	Membrane
BsBEST3096_06370	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BsBEST3096_06390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BsBEST3096_06400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BsBEST3096_06410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BsBEST3096_06420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BsBEST3096_06430	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3096_06440	COG0047	phosphoribosylformylglycinamidine synthase activity
BsBEST3096_06450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3096_06460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BsBEST3096_06470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BsBEST3096_06480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BsBEST3096_06490	COG0138	bifunctional purine biosynthesis protein purh
BsBEST3096_06500	COG0151	Belongs to the GarS family
BsBEST3096_06510	COG1522	sequence-specific DNA binding
BsBEST3096_06520	COG0531	amino acid
BsBEST3096_06540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3096_06550	COG1470	cell adhesion involved in biofilm formation
BsBEST3096_06560	COG4496	protein, YerC YecD
BsBEST3096_06570	COG0069	glutamate synthase activity
BsBEST3096_06580	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BsBEST3096_06590	COG0210	DNA helicase
BsBEST3096_06600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BsBEST3096_06610	COG4851	CamS sex pheromone cAM373 precursor
BsBEST3096_06620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3096_06630	COG1285	pathogenesis
BsBEST3096_06640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3096_06650	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3096_06660	COG0154	amidase activity
BsBEST3096_06670	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3096_06680	COG1309	transcriptional regulator
BsBEST3096_06690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BsBEST3096_06700	COG1597	lipid kinase activity
BsBEST3096_06710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3096_06720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3096_06730	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3096_06740	COG1002	Type II restriction enzyme, methylase subunits
BsBEST3096_06750	COG1061	Type III restriction enzyme res subunit
BsBEST3096_06760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BsBEST3096_06800	COG5444	nuclease activity
BsBEST3096_06820	COG3391	amine dehydrogenase activity
BsBEST3096_06830	COG0457	Tetratricopeptide repeat
BsBEST3096_06850	COG0217	transcriptional regulatory protein
BsBEST3096_06870	COG1309	transcriptional regulator
BsBEST3096_06880	COG3631	Ketosteroid isomerase-related protein
BsBEST3096_06890	COG0702	epimerase
BsBEST3096_06920	COG3546	catalase activity
BsBEST3096_06930	COG0454	-acetyltransferase
BsBEST3096_06950	COG5578	integral membrane protein
BsBEST3096_06960	COG2972	Histidine kinase
BsBEST3096_06970	COG2207	Transcriptional regulator
BsBEST3096_06970	COG4753	response regulator
BsBEST3096_06980	COG1653	transport
BsBEST3096_06990	COG1175	transmembrane transport
BsBEST3096_07000	COG0395	ABC-type sugar transport system, permease component
BsBEST3096_07010	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3096_07020	COG2207	Transcriptional regulator
BsBEST3096_07030	COG2755	lipolytic protein G-D-S-L family
BsBEST3096_07050	COG5578	integral membrane protein
BsBEST3096_07060	COG3401	FG-GAP repeat protein
BsBEST3096_07070	COG3401	FG-GAP repeat protein
BsBEST3096_07080	COG2755	lipolytic protein G-D-S-L family
BsBEST3096_07090	COG1874	Beta-galactosidase
BsBEST3096_07110	COG1653	transport
BsBEST3096_07120	COG4209	transmembrane transport
BsBEST3096_07130	COG0395	ABC-type sugar transport system, permease component
BsBEST3096_07140	COG1486	melibiose metabolic process
BsBEST3096_07150	COG2323	membrane
BsBEST3096_07160	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3096_07170	COG0346	lactoylglutathione lyase activity
BsBEST3096_07190	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3096_07210	COG5583	Uncharacterized small protein (DUF2292)
BsBEST3096_07220	COG0670	Belongs to the BI1 family
BsBEST3096_07230	COG0697	spore germination
BsBEST3096_07240	COG1846	Transcriptional regulator
BsBEST3096_07250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3096_07270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3096_07270	COG2124	cytochrome p450
BsBEST3096_07280	COG1368	sulfuric ester hydrolase activity
BsBEST3096_07290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BsBEST3096_07300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3096_07310	COG1442	glycosyl transferase family 8
BsBEST3096_07320	COG1216	Glycosyl transferase, family 2
BsBEST3096_07330	COG1442	glycosyl transferase family 8
BsBEST3096_07340	COG2223	nitrite transmembrane transporter activity
BsBEST3096_07350	COG1011	Hydrolase
BsBEST3096_07360	COG0531	amino acid
BsBEST3096_07370	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_07380	COG0840	transmembrane signaling receptor activity
BsBEST3096_07390	COG0488	(ABC) transporter
BsBEST3096_07410	COG0789	Transcriptional regulator
BsBEST3096_07420	COG2814	Major facilitator Superfamily
BsBEST3096_07440	COG0488	(ABC) transporter
BsBEST3096_07450	COG0513	Belongs to the DEAD box helicase family
BsBEST3096_07460	COG0456	acetyltransferase
BsBEST3096_07470	COG2130	NADP-dependent
BsBEST3096_07490	COG2211	Major facilitator Superfamily
BsBEST3096_07500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BsBEST3096_07510	COG1120	ATPase activity
BsBEST3096_07520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3096_07530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3096_07540	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3096_07570	COG3866	Pectate lyase
BsBEST3096_07580	COG0471	metal ion transport
BsBEST3096_07590	COG3290	protein histidine kinase activity
BsBEST3096_07600	COG4565	transcriptional regulatory protein
BsBEST3096_07610	COG3181	Tripartite tricarboxylate transporter family receptor
BsBEST3096_07620	COG2851	Citrate transporter
BsBEST3096_07630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3096_07640	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BsBEST3096_07650	COG1254	Belongs to the acylphosphatase family
BsBEST3096_07660	COG2258	MOSC domain
BsBEST3096_07700	COG0024	Methionine aminopeptidase
BsBEST3096_07710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3096_07710	COG1263	PTS System
BsBEST3096_07720	COG1368	sulfuric ester hydrolase activity
BsBEST3096_07740	COG1115	amino acid carrier protein
BsBEST3096_07750	COG0531	amino acid
BsBEST3096_07780	COG0697	spore germination
BsBEST3096_07790	COG1263	PTS System
BsBEST3096_07790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3096_07800	COG0366	Alpha amylase catalytic
BsBEST3096_07810	COG2188	Transcriptional regulator
BsBEST3096_07820	COG0778	Nitroreductase
BsBEST3096_07830	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3096_07840	COG0693	protein deglycase activity
BsBEST3096_07850	COG2814	Major facilitator Superfamily
BsBEST3096_07860	COG4840	Belongs to the UPF0435 family
BsBEST3096_07870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3096_07880	COG4980	gas vesicle protein
BsBEST3096_07890	COG1295	ribonuclease BN
BsBEST3096_07900	COG0477	Major facilitator Superfamily
BsBEST3096_07910	COG0387	Pfam Sodium calcium exchanger
BsBEST3096_07930	COG0668	transmembrane transport
BsBEST3096_07940	COG0535	radical SAM domain protein
BsBEST3096_07960	COG0726	polysaccharide deacetylase
BsBEST3096_07970	COG2084	Dehydrogenase
BsBEST3096_07980	COG0598	Magnesium transport protein CorA
BsBEST3096_07990	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3096_08000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3096_08020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3096_08030	COG4637	Psort location Cytoplasmic, score
BsBEST3096_08050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3096_08060	COG0022	dehydrogenase e1 component
BsBEST3096_08070	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3096_08080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3096_08090	COG3284	Transcriptional regulator
BsBEST3096_08110	COG1742	UPF0060 membrane protein
BsBEST3096_08160	COG4842	Belongs to the WXG100 family
BsBEST3096_08170	COG1486	melibiose metabolic process
BsBEST3096_08180	COG1737	Transcriptional regulator
BsBEST3096_08190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3096_08190	COG1263	PTS System
BsBEST3096_08200	COG1132	(ABC) transporter
BsBEST3096_08210	COG1132	(ABC) transporter
BsBEST3096_08220	COG2259	Doxx family
BsBEST3096_08230	COG2514	catechol 2,3-dioxygenase activity
BsBEST3096_08240	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3096_08240	COG4977	sequence-specific DNA binding
BsBEST3096_08250	COG2814	Major facilitator Superfamily
BsBEST3096_08260	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3096_08270	COG0673	inositol 2-dehydrogenase activity
BsBEST3096_08280	COG4585	Histidine kinase
BsBEST3096_08290	COG2197	response regulator
BsBEST3096_08300	COG1131	(ABC) transporter
BsBEST3096_08310	COG1511	domain protein
BsBEST3096_08310	COG0842	Transport permease protein
BsBEST3096_08320	COG0842	Transport permease protein
BsBEST3096_08330	COG1695	Transcriptional regulator
BsBEST3096_08340	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3096_08350	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BsBEST3096_08360	COG1309	transcriptional regulator
BsBEST3096_08370	COG2814	Major facilitator Superfamily
BsBEST3096_08380	COG2318	DinB family
BsBEST3096_08390	COG2814	Major facilitator Superfamily
BsBEST3096_08400	COG1846	Transcriptional regulator
BsBEST3096_08410	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BsBEST3096_08410	COG0392	lysyltransferase activity
BsBEST3096_08420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3096_08430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3096_08440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3096_08450	COG0384	phenazine biosynthesis protein PhzF
BsBEST3096_08460	COG0778	Nitroreductase
BsBEST3096_08480	COG1090	epimerase
BsBEST3096_08490	COG2137	regulation of response to DNA damage stimulus
BsBEST3096_08510	COG2814	Major facilitator Superfamily
BsBEST3096_08540	COG3103	Sh3 type 3 domain protein
BsBEST3096_08550	COG5658	integral membrane protein
BsBEST3096_08560	COG0596	Alpha beta hydrolase
BsBEST3096_08570	COG0463	Glycosyl transferase, family 2
BsBEST3096_08580	COG4485	Bacterial membrane protein, YfhO
BsBEST3096_08590	COG1988	membrane-bound metal-dependent
BsBEST3096_08600	COG1194	a g-specific adenine glycosylase
BsBEST3096_08620	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_08650	COG3557	Belongs to the UPF0374 family
BsBEST3096_08660	COG1132	(ABC) transporter
BsBEST3096_08670	COG4129	membrane
BsBEST3096_08680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3096_08690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BsBEST3096_08700	COG0735	belongs to the Fur family
BsBEST3096_08730	COG4326	sporulation control protein
BsBEST3096_08750	COG3340	Belongs to the peptidase S51 family
BsBEST3096_08760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BsBEST3096_08770	COG0277	FAD linked oxidase domain protein
BsBEST3096_08790	COG0753	catalase activity
BsBEST3096_08800	COG1116	anion transmembrane transporter activity
BsBEST3096_08810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3096_08820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3096_08830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3096_08850	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BsBEST3096_08870	COG1476	TRANSCRIPTIONal
BsBEST3096_08880	COG3382	B3 4 domain protein
BsBEST3096_08890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BsBEST3096_08910	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BsBEST3096_08920	COG0789	Transcriptional regulator
BsBEST3096_08930	COG1664	Polymer-forming cytoskeletal
BsBEST3096_08940	COG1664	Polymer-forming cytoskeletal
BsBEST3096_08950	COG2766	serine protein kinase
BsBEST3096_08960	COG2718	Belongs to the UPF0229 family
BsBEST3096_08970	COG1846	Transcriptional regulator
BsBEST3096_08980	COG1566	PFAM secretion protein HlyD family protein
BsBEST3096_08990	COG2814	Major facilitator Superfamily
BsBEST3096_09000	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3096_09030	COG1725	Transcriptional regulator
BsBEST3096_09040	COG1131	(ABC) transporter
BsBEST3096_09050	COG1131	(ABC) transporter
BsBEST3096_09060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3096_09070	COG1278	Cold shock
BsBEST3096_09080	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3096_09090	COG3706	GGDEF domain
BsBEST3096_09100	COG1823	symporter activity
BsBEST3096_09140	COG5577	PFAM Coat F domain
BsBEST3096_09150	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3096_09150	COG1525	nuclease
BsBEST3096_09150	COG4085	toxin activity
BsBEST3096_09160	COG3764	Sortase (surface protein transpeptidase)
BsBEST3096_09170	COG0564	pseudouridine synthase activity
BsBEST3096_09190	COG0517	IMP dehydrogenase activity
BsBEST3096_09200	COG0517	IMP dehydrogenase activity
BsBEST3096_09210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3096_09220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3096_09220	COG3153	acetyltransferase
BsBEST3096_09240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3096_09250	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BsBEST3096_09260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BsBEST3096_09270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BsBEST3096_09280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BsBEST3096_09290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3096_09300	COG2203	Gaf domain
BsBEST3096_09300	COG4585	Histidine kinase
BsBEST3096_09310	COG2197	response regulator
BsBEST3096_09320	COG0431	NADPH-dependent FMN reductase
BsBEST3096_09350	COG0791	NLP P60 protein
BsBEST3096_09350	COG1388	LysM domain
BsBEST3096_09360	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3096_09370	COG0668	transmembrane transport
BsBEST3096_09380	COG2719	SpoVR family
BsBEST3096_09390	COG1785	Belongs to the alkaline phosphatase family
BsBEST3096_09400	COG1388	LysM domain
BsBEST3096_09400	COG0791	NLP P60 protein
BsBEST3096_09410	COG0583	DNA-binding transcription factor activity
BsBEST3096_09420	COG0372	Belongs to the citrate synthase family
BsBEST3096_09430	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_09440	COG0531	amino acid
BsBEST3096_09450	COG0733	neurotransmitter:sodium symporter activity
BsBEST3096_09460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3096_09470	COG0456	acetyltransferase
BsBEST3096_09500	COG1595	DNA-templated transcription, initiation
BsBEST3096_09510	COG0667	Aldo Keto reductase
BsBEST3096_09520	COG0204	Acyl-transferase
BsBEST3096_09530	COG1253	flavin adenine dinucleotide binding
BsBEST3096_09540	COG0789	Transcriptional regulator
BsBEST3096_09550	COG0436	Aminotransferase
BsBEST3096_09560	COG1253	flavin adenine dinucleotide binding
BsBEST3096_09570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3096_09580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3096_09590	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3096_09610	COG0668	transmembrane transport
BsBEST3096_09620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BsBEST3096_09630	COG0726	polysaccharide deacetylase
BsBEST3096_09640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3096_09650	COG1757	Na H antiporter
BsBEST3096_09660	COG0589	response to stress
BsBEST3096_09670	COG1132	(ABC) transporter
BsBEST3096_09680	COG1132	(ABC) transporter
BsBEST3096_09690	COG0702	epimerase
BsBEST3096_09720	COG0189	ligase activity
BsBEST3096_09730	COG0189	ligase activity
BsBEST3096_09740	COG4399	Belongs to the UPF0754 family
BsBEST3096_09750	COG3679	Belongs to the UPF0342 family
BsBEST3096_09760	COG4335	DNA alkylation repair
BsBEST3096_09770	COG0561	phosphatase activity
BsBEST3096_09780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3096_09790	COG0475	glutathione-regulated potassium exporter activity
BsBEST3096_09800	COG0490	domain, Protein
BsBEST3096_09820	COG1024	Enoyl-CoA hydratase
BsBEST3096_09840	COG4152	abc transporter atp-binding protein
BsBEST3096_09850	COG1668	transmembrane transport
BsBEST3096_09860	COG0420	3'-5' exonuclease activity
BsBEST3096_09870	COG4717	serine-type aminopeptidase activity
BsBEST3096_09880	COG3481	metal-dependent phosphohydrolase, HD sub domain
BsBEST3096_09900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3096_09930	COG1846	Transcriptional regulator
BsBEST3096_09940	COG4980	gas vesicle protein
BsBEST3096_09960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BsBEST3096_09970	COG0537	adenosine 5'-monophosphoramidase activity
BsBEST3096_09980	COG1131	(ABC) transporter
BsBEST3096_09990	COG4473	ABC transporter
BsBEST3096_10010	COG1473	amidohydrolase
BsBEST3096_10020	COG1473	amidohydrolase
BsBEST3096_10030	COG3069	C4-dicarboxylate transmembrane transporter activity
BsBEST3096_10040	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3096_10050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3096_10060	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BsBEST3096_10070	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BsBEST3096_10080	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BsBEST3096_10090	COG1309	transcriptional regulator
BsBEST3096_10100	COG1511	domain protein
BsBEST3096_10110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3096_10120	COG4377	Putative membrane peptidase family (DUF2324)
BsBEST3096_10140	COG1363	Peptidase, m42
BsBEST3096_10150	COG4405	Protein conserved in bacteria
BsBEST3096_10160	COG1301	dicarboxylic acid transport
BsBEST3096_10170	COG1234	tRNA 3'-trailer cleavage
BsBEST3096_10180	COG0095	Lipoate-protein ligase
BsBEST3096_10190	COG0702	epimerase
BsBEST3096_10200	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3096_10220	COG0501	Belongs to the peptidase M48B family
BsBEST3096_10230	COG1404	Belongs to the peptidase S8 family
BsBEST3096_10240	COG0456	acetyltransferase
BsBEST3096_10250	COG0604	alcohol dehydrogenase
BsBEST3096_10260	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3096_10270	COG0406	alpha-ribazole phosphatase activity
BsBEST3096_10280	COG0183	Belongs to the thiolase family
BsBEST3096_10290	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3096_10300	COG1268	BioY protein
BsBEST3096_10310	COG0840	transmembrane signaling receptor activity
BsBEST3096_10320	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3096_10320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3096_10330	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_10350	COG4903	ComK protein
BsBEST3096_10360	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_10380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3096_10410	COG0398	Pfam SNARE associated Golgi protein
BsBEST3096_10420	COG0681	Belongs to the peptidase S26 family
BsBEST3096_10430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3096_10440	COG1846	Transcriptional regulator
BsBEST3096_10450	COG0738	Major facilitator superfamily
BsBEST3096_10470	COG0673	inositol 2-dehydrogenase activity
BsBEST3096_10480	COG0561	phosphatase activity
BsBEST3096_10490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3096_10500	COG1609	Transcriptional regulator
BsBEST3096_10510	COG3180	Ammonia monooxygenase
BsBEST3096_10520	COG2814	Major facilitator Superfamily
BsBEST3096_10520	COG0477	Major facilitator Superfamily
BsBEST3096_10530	COG4533	DNA binding
BsBEST3096_10550	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BsBEST3096_10560	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BsBEST3096_10570	COG1074	ATP-dependent DNA helicase activity
BsBEST3096_10580	COG0420	3'-5' exonuclease activity
BsBEST3096_10590	COG0419	ATPase involved in DNA repair
BsBEST3096_10600	COG1403	HNH endonuclease
BsBEST3096_10680	COG0179	Fumarylacetoacetate (FAA) hydrolase
BsBEST3096_10700	COG1404	Belongs to the peptidase S8 family
BsBEST3096_10720	COG0367	asparagine synthase
BsBEST3096_10730	COG2318	DinB family
BsBEST3096_10740	COG1562	ergosterol biosynthetic process
BsBEST3096_10750	COG0534	Mate efflux family protein
BsBEST3096_10760	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3096_10760	COG2207	Transcriptional regulator
BsBEST3096_10770	COG1609	Transcriptional regulator
BsBEST3096_10780	COG0673	inositol 2-dehydrogenase activity
BsBEST3096_10790	COG2318	DinB family
BsBEST3096_10800	COG1279	arginine transmembrane transporter activity
BsBEST3096_10810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3096_10820	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3096_10830	COG2267	carboxylic ester hydrolase activity
BsBEST3096_10840	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3096_10850	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3096_10860	COG0175	sulfate reduction
BsBEST3096_10870	COG2045	Belongs to the ComB family
BsBEST3096_10880	COG1809	phosphosulfolactate synthase activity
BsBEST3096_10890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3096_10900	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3096_10910	COG2814	Major facilitator Superfamily
BsBEST3096_10920	COG0454	-acetyltransferase
BsBEST3096_10930	COG2153	protein acetylation
BsBEST3096_10940	COG0646	methionine synthase
BsBEST3096_10940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BsBEST3096_10950	COG1666	GTP binding
BsBEST3096_10960	COG2996	Protein conserved in bacteria
BsBEST3096_11000	COG1695	Transcriptional regulator
BsBEST3096_11030	COG3227	Zinc metalloprotease (Elastase)
BsBEST3096_11040	COG1307	EDD domain protein, DegV family
BsBEST3096_11050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3096_11080	COG0561	phosphatase activity
BsBEST3096_11090	COG1073	alpha beta
BsBEST3096_11100	COG2151	metal-sulfur cluster biosynthetic enzyme
BsBEST3096_11120	COG0277	FAD linked oxidase domain protein
BsBEST3096_11130	COG2271	Major facilitator Superfamily
BsBEST3096_11140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BsBEST3096_11150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BsBEST3096_11170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3096_11180	COG0505	Belongs to the CarA family
BsBEST3096_11190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3096_11200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BsBEST3096_11230	COG2267	carboxylic ester hydrolase activity
BsBEST3096_11250	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3096_11280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3096_11290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3096_11300	COG5504	Zn-dependent protease
BsBEST3096_11310	COG0444	Belongs to the ABC transporter superfamily
BsBEST3096_11320	COG4608	Belongs to the ABC transporter superfamily
BsBEST3096_11350	COG0601	transmembrane transport
BsBEST3096_11360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3096_11380	COG0180	Tryptophanyl-tRNA synthetase
BsBEST3096_11390	COG4166	transmembrane transport
BsBEST3096_11400	COG0601	transmembrane transport
BsBEST3096_11410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3096_11420	COG0444	Belongs to the ABC transporter superfamily
BsBEST3096_11430	COG4608	Belongs to the ABC transporter superfamily
BsBEST3096_11440	COG2814	Major facilitator Superfamily
BsBEST3096_11450	COG0456	acetyltransferase
BsBEST3096_11460	COG1393	Belongs to the ArsC family
BsBEST3096_11470	COG0861	Integral membrane protein TerC family
BsBEST3096_11480	COG4862	establishment of competence for transformation
BsBEST3096_11490	COG4469	Competence protein
BsBEST3096_11500	COG1164	Oligoendopeptidase f
BsBEST3096_11520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3096_11530	COG2346	COG2346, Truncated hemoglobins
BsBEST3096_11540	COG0741	lytic transglycosylase activity
BsBEST3096_11550	COG4116	CYTH
BsBEST3096_11570	COG2357	RelA SpoT domain protein
BsBEST3096_11580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3096_11590	COG0564	pseudouridine synthase activity
BsBEST3096_11600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BsBEST3096_11610	COG0475	glutathione-regulated potassium exporter activity
BsBEST3096_11610	COG0569	domain protein
BsBEST3096_11620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BsBEST3096_11630	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3096_11640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3096_11650	COG2104	thiamine diphosphate biosynthetic process
BsBEST3096_11660	COG2022	thiamine diphosphate biosynthetic process
BsBEST3096_11670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3096_11680	COG0351	phosphomethylpyrimidine kinase
BsBEST3096_11690	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BsBEST3096_11800	COG0210	DNA helicase
BsBEST3096_11820	COG2153	protein acetylation
BsBEST3096_11830	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3096_11840	COG2382	esterase
BsBEST3096_11850	COG0626	cystathionine gamma-synthase activity
BsBEST3096_11860	COG0626	cystathionine gamma-synthase activity
BsBEST3096_11870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3096_11880	COG5505	Protein of unknown function (DUF819)
BsBEST3096_11940	COG3677	Transposase
BsBEST3096_11970	COG5484	DNA packaging
BsBEST3096_11980	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3096_11990	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_12010	COG3711	transcriptional antiterminator
BsBEST3096_12010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3096_12020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3096_12020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3096_12020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3096_12030	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3096_12050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3096_12070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3096_12110	COG0109	protoheme IX farnesyltransferase activity
BsBEST3096_12130	COG0726	polysaccharide deacetylase
BsBEST3096_12160	COG5504	Zn-dependent protease
BsBEST3096_12170	COG2205	protein histidine kinase activity
BsBEST3096_12190	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3096_12200	COG2427	Protein of unknown function (DUF1641)
BsBEST3096_12220	COG1051	belongs to the nudix hydrolase family
BsBEST3096_12240	COG2124	cytochrome p450
BsBEST3096_12250	COG1819	glycosyl
BsBEST3096_12270	COG1587	Uroporphyrinogen-III synthase
BsBEST3096_12280	COG0390	transport system, permease component
BsBEST3096_12290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3096_12300	COG0697	spore germination
BsBEST3096_12310	COG4297	protein containing double-stranded beta helix domain
BsBEST3096_12330	COG1252	NADH dehydrogenase
BsBEST3096_12340	COG1904	glucuronate isomerase
BsBEST3096_12350	COG2211	Major facilitator Superfamily
BsBEST3096_12360	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BsBEST3096_12370	COG1063	alcohol dehydrogenase
BsBEST3096_12380	COG1312	Catalyzes the dehydration of D-mannonate
BsBEST3096_12390	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_12400	COG2271	Major facilitator Superfamily
BsBEST3096_12410	COG1609	Transcriptional regulator
BsBEST3096_12420	COG0246	Mannitol dehydrogenase
BsBEST3096_12430	COG2721	sulfolactate sulfo-lyase activity
BsBEST3096_12440	COG0730	response to heat
BsBEST3096_12450	COG2318	DinB family
BsBEST3096_12460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3096_12470	COG0457	Tetratricopeptide repeat
BsBEST3096_12490	COG2350	Protein conserved in bacteria
BsBEST3096_12500	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_12500	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_12500	COG1388	LysM domain
BsBEST3096_12520	COG4195	phage-related replication protein
BsBEST3096_12530	COG3546	catalase activity
BsBEST3096_12540	COG2856	Zn peptidase
BsBEST3096_12550	COG1396	sequence-specific DNA binding
BsBEST3096_12570	COG1522	sequence-specific DNA binding
BsBEST3096_12580	COG1484	DNA-dependent DNA replication
BsBEST3096_12620	COG1595	DNA-templated transcription, initiation
BsBEST3096_12630	COG5484	DNA packaging
BsBEST3096_12630	COG3728	DNA packaging
BsBEST3096_12640	COG1783	phage Terminase large subunit
BsBEST3096_12650	COG5518	Phage portal protein
BsBEST3096_12660	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3096_12670	COG4653	Phage capsid family
BsBEST3096_12770	COG5412	phage tail tape measure protein
BsBEST3096_12770	COG3953	SLT domain
BsBEST3096_12780	COG1652	LysM domain
BsBEST3096_12790	COG4193	domain, Protein
BsBEST3096_12810	COG3628	GPW Gp25 family protein
BsBEST3096_12820	COG3299	homolog of phage Mu protein gp47
BsBEST3096_12830	COG3778	Protein conserved in bacteria
BsBEST3096_12910	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_12910	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_12940	COG0306	phosphate transporter
BsBEST3096_12950	COG1392	Phosphate transport regulator
BsBEST3096_12960	COG0531	amino acid
BsBEST3096_12970	COG0346	lactoylglutathione lyase activity
BsBEST3096_12990	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3096_13000	COG0463	Glycosyl transferase, family 2
BsBEST3096_13020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3096_13030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3096_13040	COG2362	D-Aminopeptidase
BsBEST3096_13050	COG0601	transmembrane transport
BsBEST3096_13060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3096_13070	COG0444	Belongs to the ABC transporter superfamily
BsBEST3096_13080	COG4166	transmembrane transport
BsBEST3096_13090	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3096_13100	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3096_13110	COG0791	NLP P60 protein
BsBEST3096_13120	COG4608	Belongs to the ABC transporter superfamily
BsBEST3096_13130	COG2706	6-phosphogluconolactonase activity
BsBEST3096_13140	COG1834	amidinotransferase
BsBEST3096_13150	COG1607	acyl-coa hydrolase
BsBEST3096_13160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BsBEST3096_13160	COG1017	nitric oxide dioxygenase activity
BsBEST3096_13180	COG2323	membrane
BsBEST3096_13190	COG2318	DinB family
BsBEST3096_13200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3096_13210	COG2076	Multidrug Resistance protein
BsBEST3096_13220	COG2076	Multidrug Resistance protein
BsBEST3096_13230	COG0788	formyltetrahydrofolate deformylase activity
BsBEST3096_13240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3096_13250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BsBEST3096_13260	COG1764	response to oxidative stress
BsBEST3096_13270	COG1846	Transcriptional regulator
BsBEST3096_13280	COG1764	response to oxidative stress
BsBEST3096_13300	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3096_13310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3096_13320	COG1404	Belongs to the peptidase S8 family
BsBEST3096_13330	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3096_13340	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3096_13350	COG1122	ATPase activity
BsBEST3096_13360	COG4721	ABC-type cobalt transport system, permease component
BsBEST3096_13380	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_13390	COG3850	Histidine kinase
BsBEST3096_13390	COG5002	protein histidine kinase activity
BsBEST3096_13400	COG3212	peptidase
BsBEST3096_13410	COG3212	peptidase
BsBEST3096_13440	COG2239	Acts as a magnesium transporter
BsBEST3096_13450	COG0789	Transcriptional regulator
BsBEST3096_13480	COG1846	Transcriptional regulator
BsBEST3096_13490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3096_13500	COG0726	polysaccharide deacetylase
BsBEST3096_13510	COG1408	metallophosphoesterase
BsBEST3096_13530	COG0463	Glycosyl transferase, family 2
BsBEST3096_13540	COG1793	dna ligase
BsBEST3096_13540	COG3285	dna ligase
BsBEST3096_13550	COG1793	dna ligase
BsBEST3096_13550	COG3285	dna ligase
BsBEST3096_13560	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BsBEST3096_13570	COG5001	Diguanylate cyclase
BsBEST3096_13570	COG3300	MHYT domain
BsBEST3096_13580	COG0586	Pfam SNARE associated Golgi protein
BsBEST3096_13590	COG0861	Integral membrane protein TerC family
BsBEST3096_13600	COG1191	sigma factor activity
BsBEST3096_13640	COG0501	Belongs to the peptidase M48B family
BsBEST3096_13650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3096_13680	COG3594	Acyltransferase
BsBEST3096_13690	COG5002	protein histidine kinase activity
BsBEST3096_13700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3096_13720	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BsBEST3096_13730	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BsBEST3096_13740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3096_13750	COG0436	Aminotransferase
BsBEST3096_13760	COG1850	ribulose-bisphosphate carboxylase activity
BsBEST3096_13770	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BsBEST3096_13780	COG0235	Class ii aldolase
BsBEST3096_13790	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BsBEST3096_13800	COG3339	Conserved Protein
BsBEST3096_13830	COG3852	Histidine kinase
BsBEST3096_13840	COG1846	Transcriptional regulator
BsBEST3096_13850	COG1360	Flagellar Motor Protein
BsBEST3096_13860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3096_13870	COG0542	response to heat
BsBEST3096_13880	COG3949	Membrane
BsBEST3096_13890	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BsBEST3096_13900	COG0720	synthase
BsBEST3096_13910	COG0602	queuosine metabolic process
BsBEST3096_13920	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BsBEST3096_13930	COG1733	regulation of RNA biosynthetic process
BsBEST3096_13940	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_13950	COG1388	LysM domain
BsBEST3096_13950	COG4641	Protein conserved in bacteria
BsBEST3096_13960	COG1388	LysM domain
BsBEST3096_13970	COG3858	chitin binding
BsBEST3096_13980	COG3858	chitin binding
BsBEST3096_14000	COG4873	Protein conserved in bacteria
BsBEST3096_14020	COG3773	Cell wall hydrolase
BsBEST3096_14030	COG2244	polysaccharide biosynthetic process
BsBEST3096_14040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_14050	COG2217	Heavy metal translocating P-type atpase
BsBEST3096_14070	COG0006	proline dipeptidase activity
BsBEST3096_14090	COG1609	Transcriptional regulator
BsBEST3096_14100	COG3711	transcriptional antiterminator
BsBEST3096_14110	COG2190	(PTS) system
BsBEST3096_14110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3096_14110	COG1263	PTS System
BsBEST3096_14120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3096_14130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BsBEST3096_14150	COG1533	DNA photolyase activity
BsBEST3096_14160	COG0456	acetyltransferase
BsBEST3096_14170	COG0840	transmembrane signaling receptor activity
BsBEST3096_14180	COG2084	Dehydrogenase
BsBEST3096_14190	COG2340	Cysteine-rich secretory protein family
BsBEST3096_14200	COG0768	penicillin binding
BsBEST3096_14210	COG4191	Histidine kinase
BsBEST3096_14220	COG0436	Aminotransferase
BsBEST3096_14240	COG0835	chemotaxis
BsBEST3096_14240	COG0784	Response regulator, receiver
BsBEST3096_14260	COG2814	Major facilitator Superfamily
BsBEST3096_14270	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3096_14280	COG1408	metallophosphoesterase
BsBEST3096_14290	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_14300	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_14310	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_14330	COG2200	EAL domain
BsBEST3096_14340	COG4703	Protein of unknown function (DUF1797)
BsBEST3096_14350	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BsBEST3096_14370	COG0517	IMP dehydrogenase activity
BsBEST3096_14380	COG0583	DNA-binding transcription factor activity
BsBEST3096_14390	COG0716	FMN binding
BsBEST3096_14410	COG0716	FMN binding
BsBEST3096_14420	COG2171	N-acyltransferase activity
BsBEST3096_14430	COG1473	amidohydrolase
BsBEST3096_14450	COG0668	transmembrane transport
BsBEST3096_14460	COG0450	alkyl hydroperoxide reductase
BsBEST3096_14470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_14500	COG0746	molybdenum cofactor guanylyltransferase activity
BsBEST3096_14510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3096_14520	COG0303	'Molybdopterin
BsBEST3096_14530	COG1763	Mo-molybdopterin cofactor biosynthetic process
BsBEST3096_14540	COG0314	molybdopterin synthase activity
BsBEST3096_14550	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BsBEST3096_14560	COG1132	(ABC) transporter
BsBEST3096_14570	COG1132	(ABC) transporter
BsBEST3096_14590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3096_14600	COG1136	(ABC) transporter
BsBEST3096_14610	COG0577	efflux transmembrane transporter activity
BsBEST3096_14620	COG1349	DNA-binding transcription factor activity
BsBEST3096_14630	COG1105	Belongs to the carbohydrate kinase PfkB family
BsBEST3096_14640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3096_14640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3096_14640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3096_14650	COG0681	Belongs to the peptidase S26 family
BsBEST3096_14670	COG0488	(ABC) transporter
BsBEST3096_14680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3096_14690	COG2309	aminopeptidase activity
BsBEST3096_14710	COG1077	Cell shape determining protein MreB Mrl
BsBEST3096_14720	COG2002	toxin-antitoxin pair type II binding
BsBEST3096_14730	COG3852	Histidine kinase
BsBEST3096_14740	COG2105	PFAM AIG2 family protein
BsBEST3096_14740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BsBEST3096_14750	COG0569	domain protein
BsBEST3096_14760	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3096_14770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3096_14780	COG5503	Protein of unknown function (DUF1447)
BsBEST3096_14790	COG0561	phosphatase activity
BsBEST3096_14800	COG0242	peptide deformylase activity
BsBEST3096_14820	COG0497	DNA recombination
BsBEST3096_14830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3096_14840	COG0022	dehydrogenase e1 component
BsBEST3096_14850	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3096_14860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3096_14870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_14880	COG1982	Orn Lys Arg decarboxylase major
BsBEST3096_14890	COG4476	Belongs to the UPF0223 family
BsBEST3096_14900	COG4493	Belongs to the UPF0637 family
BsBEST3096_14920	COG0483	inositol monophosphate 1-phosphatase activity
BsBEST3096_14940	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BsBEST3096_14980	COG1595	DNA-templated transcription, initiation
BsBEST3096_15020	COG1217	gtp-binding protein TYPA
BsBEST3096_15040	COG4896	Protein conserved in bacteria
BsBEST3096_15060	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BsBEST3096_15070	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3096_15080	COG2066	Belongs to the glutaminase family
BsBEST3096_15090	COG4838	Belongs to the UPF0358 family
BsBEST3096_15110	COG0772	Belongs to the SEDS family
BsBEST3096_15120	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BsBEST3096_15130	COG1612	heme a metabolic process
BsBEST3096_15140	COG0109	protoheme IX farnesyltransferase activity
BsBEST3096_15150	COG2010	Cytochrome c
BsBEST3096_15150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3096_15160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3096_15170	COG1845	cytochrome c oxidase, subunit III
BsBEST3096_15180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3096_15190	COG3336	cytochrome c oxidase
BsBEST3096_15210	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BsBEST3096_15220	COG2340	Cysteine-rich secretory protein family
BsBEST3096_15250	COG3679	Belongs to the UPF0342 family
BsBEST3096_15260	COG4471	UPF0298 protein
BsBEST3096_15270	COG0742	ribosomal rna small subunit methyltransferase
BsBEST3096_15280	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BsBEST3096_15290	COG3314	Sporulation integral membrane protein YlbJ
BsBEST3096_15300	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3096_15310	COG3480	Lon protease (S16) C-terminal proteolytic domain
BsBEST3096_15320	COG1323	Belongs to the UPF0348 family
BsBEST3096_15330	COG1399	metal-binding, possibly nucleic acid-binding protein
BsBEST3096_15360	COG0454	-acetyltransferase
BsBEST3096_15370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3096_15380	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BsBEST3096_15390	COG2001	Belongs to the MraZ family
BsBEST3096_15400	COG0275	rRNA processing
BsBEST3096_15410	COG4839	cell division protein FtsL
BsBEST3096_15420	COG0768	penicillin binding
BsBEST3096_15430	COG0768	penicillin binding
BsBEST3096_15440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BsBEST3096_15450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3096_15460	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3096_15470	COG0772	Belongs to the SEDS family
BsBEST3096_15480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3096_15490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BsBEST3096_15500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BsBEST3096_15510	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3096_15520	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3096_15530	COG3856	small basic protein
BsBEST3096_15540	COG0849	cell division
BsBEST3096_15550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BsBEST3096_15560	COG1404	Belongs to the peptidase S8 family
BsBEST3096_15560	COG4412	M6 family metalloprotease domain protein
BsBEST3096_15580	COG1191	sigma factor activity
BsBEST3096_15590	COG1191	sigma factor activity
BsBEST3096_15600	COG1119	ATPase activity
BsBEST3096_15610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3096_15620	COG1873	PFAM PRC-barrel domain
BsBEST3096_15630	COG1496	oxidoreductase activity
BsBEST3096_15640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BsBEST3096_15650	COG1799	cell septum assembly
BsBEST3096_15660	COG0762	integral membrane protein
BsBEST3096_15670	COG2302	S4 RNA-binding domain
BsBEST3096_15680	COG3599	regulation of cell shape
BsBEST3096_15690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BsBEST3096_15700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3096_15710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BsBEST3096_15720	COG0564	pseudouridine synthase activity
BsBEST3096_15730	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BsBEST3096_15740	COG2233	PERMEase
BsBEST3096_15750	COG0540	Belongs to the ATCase OTCase family
BsBEST3096_15760	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3096_15770	COG0505	Belongs to the CarA family
BsBEST3096_15780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3096_15790	COG0543	2 iron, 2 sulfur cluster binding
BsBEST3096_15800	COG0167	dihydroorotate dehydrogenase activity
BsBEST3096_15810	COG0284	orotidine-5'-phosphate decarboxylase activity
BsBEST3096_15820	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BsBEST3096_15830	COG0175	sulfate reduction
BsBEST3096_15840	COG0306	phosphate transporter
BsBEST3096_15850	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3096_15860	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3096_15870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3096_15880	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BsBEST3096_15890	COG1648	precorrin-2 dehydrogenase activity
BsBEST3096_15900	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BsBEST3096_15910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3096_15920	COG1561	YicC-like family, N-terminal region
BsBEST3096_15940	COG0194	GDP metabolic process
BsBEST3096_15950	COG1758	RNA polymerase activity
BsBEST3096_15960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3096_15970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3096_15980	COG0242	peptide deformylase activity
BsBEST3096_15990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BsBEST3096_16000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BsBEST3096_16000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3096_16010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BsBEST3096_16020	COG0631	protein serine/threonine phosphatase activity
BsBEST3096_16030	COG0515	serine threonine protein kinase
BsBEST3096_16030	COG2815	serine threonine protein kinase
BsBEST3096_16040	COG1162	GTPase activity
BsBEST3096_16050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BsBEST3096_16060	COG1564	THIamine pyrophosphokinase
BsBEST3096_16070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BsBEST3096_16080	COG1302	Protein conserved in bacteria
BsBEST3096_16090	COG1461	Dihydroxyacetone kinase
BsBEST3096_16100	COG1760	l-serine dehydratase
BsBEST3096_16110	COG1760	l-serine dehydratase
BsBEST3096_16120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BsBEST3096_16130	COG1349	DNA-binding transcription factor activity
BsBEST3096_16130	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3096_16140	COG0416	fatty acid biosynthetic process
BsBEST3096_16150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3096_16160	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_16180	COG0571	ribonuclease III activity
BsBEST3096_16190	COG1196	nuclear chromosome segregation
BsBEST3096_16200	COG0552	protein localization to endoplasmic reticulum
BsBEST3096_16220	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BsBEST3096_16230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BsBEST3096_16240	COG0228	four-way junction DNA binding
BsBEST3096_16250	COG1837	Belongs to the UPF0109 family
BsBEST3096_16270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BsBEST3096_16280	COG0336	Belongs to the RNA methyltransferase TrmD family
BsBEST3096_16290	COG0335	large ribosomal subunit rRNA binding
BsBEST3096_16300	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3096_16310	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3096_16330	COG2257	FlhB HrpN YscU SpaS Family
BsBEST3096_16340	COG0045	succinate-CoA ligase (ADP-forming) activity
BsBEST3096_16350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BsBEST3096_16360	COG0758	DNA mediated transformation
BsBEST3096_16370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3096_16380	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BsBEST3096_16390	COG4974	Belongs to the 'phage' integrase family
BsBEST3096_16400	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BsBEST3096_16410	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BsBEST3096_16420	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3096_16430	COG1815	bacterial-type flagellum-dependent cell motility
BsBEST3096_16440	COG1558	bacterial-type flagellum-dependent cell motility
BsBEST3096_16450	COG1677	Flagellar hook-basal body complex protein FliE
BsBEST3096_16460	COG1766	The M ring may be actively involved in energy transduction
BsBEST3096_16470	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3096_16480	COG1317	bacterial-type flagellum organization
BsBEST3096_16490	COG1157	protein secretion by the type III secretion system
BsBEST3096_16500	COG2882	bacterial-type flagellum organization
BsBEST3096_16510	COG3334	PFAM MgtE intracellular
BsBEST3096_16520	COG3144	bacterial-type flagellum assembly
BsBEST3096_16530	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BsBEST3096_16540	COG4786	Flagellar basal body rod
BsBEST3096_16550	COG1582	Flagellar protein (FlbD)
BsBEST3096_16560	COG1580	Controls the rotational direction of flagella during chemotaxis
BsBEST3096_16570	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3096_16580	COG1776	CheC inhibitor of MCP methylation
BsBEST3096_16580	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3096_16590	COG2201	protein-glutamate methylesterase activity
BsBEST3096_16600	COG3190	flagellar
BsBEST3096_16610	COG1338	Plays a role in the flagellum-specific transport system
BsBEST3096_16620	COG1987	bacterial-type flagellum assembly
BsBEST3096_16630	COG1684	flagellar biosynthetic protein fliR
BsBEST3096_16640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3096_16650	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3096_16660	COG1419	protein localization to endoplasmic reticulum
BsBEST3096_16670	COG0455	bacterial-type flagellum organization
BsBEST3096_16680	COG2201	protein-glutamate methylesterase activity
BsBEST3096_16690	COG0643	Histidine kinase
BsBEST3096_16690	COG2198	Histidine kinase
BsBEST3096_16700	COG0835	chemotaxis
BsBEST3096_16710	COG1776	CheC inhibitor of MCP methylation
BsBEST3096_16720	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BsBEST3096_16730	COG1191	sigma factor activity
BsBEST3096_16750	COG0052	Belongs to the universal ribosomal protein uS2 family
BsBEST3096_16760	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BsBEST3096_16770	COG0528	UMP kinase activity
BsBEST3096_16780	COG0233	cytoplasmic translational termination
BsBEST3096_16790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BsBEST3096_16800	COG4589	Belongs to the CDS family
BsBEST3096_16810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BsBEST3096_16820	COG0750	zinc metalloprotease
BsBEST3096_16830	COG0442	prolyl-tRNA aminoacylation
BsBEST3096_16840	COG2176	DNA-directed DNA polymerase activity
BsBEST3096_16850	COG0779	Required for maturation of 30S ribosomal subunits
BsBEST3096_16860	COG0195	Participates in both transcription termination and antitermination
BsBEST3096_16870	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BsBEST3096_16880	COG1358	cellular component organization or biogenesis
BsBEST3096_16890	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BsBEST3096_16900	COG1550	Protein conserved in bacteria
BsBEST3096_16910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BsBEST3096_16920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BsBEST3096_16930	COG0196	riboflavin kinase activity
BsBEST3096_16940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BsBEST3096_16950	COG1185	polyribonucleotide nucleotidyltransferase activity
BsBEST3096_16960	COG0726	polysaccharide deacetylase
BsBEST3096_16970	COG0612	Peptidase, M16
BsBEST3096_16980	COG1873	PFAM PRC-barrel domain
BsBEST3096_16990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3096_17000	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3096_17010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BsBEST3096_17020	COG0527	aspartate kinase activity
BsBEST3096_17030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3096_17040	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3096_17050	COG0740	serine-type endopeptidase activity
BsBEST3096_17070	COG1674	ftsk spoiiie
BsBEST3096_17070	COG4980	gas vesicle protein
BsBEST3096_17080	COG2188	Transcriptional regulator
BsBEST3096_17090	COG2814	Major facilitator Superfamily
BsBEST3096_17100	COG0612	Peptidase, M16
BsBEST3096_17110	COG0612	Peptidase, M16
BsBEST3096_17120	COG0300	oxidoreductase activity
BsBEST3096_17160	COG1426	Protein conserved in bacteria
BsBEST3096_17170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BsBEST3096_17180	COG1058	Belongs to the CinA family
BsBEST3096_17180	COG1546	Belongs to the CinA family
BsBEST3096_17190	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BsBEST3096_17200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3096_17210	COG1418	mRNA catabolic process
BsBEST3096_17220	COG1692	metallophosphoesterase
BsBEST3096_17230	COG2359	stage V sporulation protein S
BsBEST3096_17240	COG1063	alcohol dehydrogenase
BsBEST3096_17250	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3096_17260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3096_17270	COG4550	Control of competence regulator ComK, YlbF/YmcA
BsBEST3096_17290	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BsBEST3096_17300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BsBEST3096_17330	COG3226	Transcriptional regulator
BsBEST3096_17340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3096_17360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3096_17370	COG3321	synthase
BsBEST3096_17380	COG2070	2-Nitropropane dioxygenase
BsBEST3096_17380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3096_17390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3096_17400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3096_17410	COG3425	synthase
BsBEST3096_17420	COG1024	Enoyl-CoA hydratase
BsBEST3096_17430	COG1024	Enoyl-CoA hydratase
BsBEST3096_17440	COG0300	oxidoreductase activity
BsBEST3096_17440	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3096_17440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_17440	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_17440	COG3321	synthase
BsBEST3096_17450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3096_17450	COG4221	oxidoreductase activity
BsBEST3096_17450	COG0300	oxidoreductase activity
BsBEST3096_17450	COG3321	synthase
BsBEST3096_17460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_17460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3096_17460	COG3321	synthase
BsBEST3096_17460	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_17460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3096_17470	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_17470	COG3321	synthase
BsBEST3096_17470	COG4221	oxidoreductase activity
BsBEST3096_17470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_17480	COG4221	oxidoreductase activity
BsBEST3096_17480	COG3321	synthase
BsBEST3096_17480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_17480	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_17490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3096_17490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BsBEST3096_17490	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3096_17490	COG3321	synthase
BsBEST3096_17500	COG2124	cytochrome p450
BsBEST3096_17520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3096_17530	COG1404	Belongs to the peptidase S8 family
BsBEST3096_17540	COG4195	phage-related replication protein
BsBEST3096_17550	COG1764	response to oxidative stress
BsBEST3096_17560	COG2076	Multidrug Resistance protein
BsBEST3096_17570	COG2076	Multidrug Resistance protein
BsBEST3096_17600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BsBEST3096_17610	COG1923	regulation of RNA biosynthetic process
BsBEST3096_17640	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3096_17650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3096_17660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3096_17670	COG4112	unkown
BsBEST3096_17680	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_17690	COG0464	growth
BsBEST3096_17700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BsBEST3096_17710	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BsBEST3096_17720	COG0789	Transcriptional regulator
BsBEST3096_17730	COG0174	glutamine synthetase
BsBEST3096_17770	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3096_17790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3096_17840	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3096_17850	COG2211	Major facilitator Superfamily
BsBEST3096_17860	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3096_17870	COG1940	carbohydrate kinase activity
BsBEST3096_17880	COG2115	Belongs to the xylose isomerase family
BsBEST3096_17890	COG1070	Carbohydrate kinase
BsBEST3096_17900	COG1525	nuclease
BsBEST3096_17910	COG2814	Major facilitator Superfamily
BsBEST3096_17920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3096_17940	COG0756	dUTP diphosphatase activity
BsBEST3096_17990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3096_18040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3096_18060	COG3832	glyoxalase III activity
BsBEST3096_18080	COG0697	spore germination
BsBEST3096_18090	COG0531	amino acid
BsBEST3096_18150	COG4195	phage-related replication protein
BsBEST3096_18170	COG0346	lactoylglutathione lyase activity
BsBEST3096_18180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BsBEST3096_18190	COG1388	LysM domain
BsBEST3096_18200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3096_18210	COG4224	UPF0291 protein
BsBEST3096_18220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BsBEST3096_18240	COG3763	UPF0154 protein
BsBEST3096_18260	COG0785	Cytochrome C biogenesis protein
BsBEST3096_18270	COG2201	protein-glutamate methylesterase activity
BsBEST3096_18280	COG4846	Membrane protein involved in cytochrome C biogenesis
BsBEST3096_18300	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3096_18330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BsBEST3096_18340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_18380	COG0824	Thioesterase
BsBEST3096_18400	COG4841	protein insertion into membrane
BsBEST3096_18410	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BsBEST3096_18420	COG1832	CoA-binding protein
BsBEST3096_18430	COG0187	DNA topoisomerase II activity
BsBEST3096_18440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3096_18460	COG1115	amino acid carrier protein
BsBEST3096_18470	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BsBEST3096_18490	COG5520	Belongs to the glycosyl hydrolase 30 family
BsBEST3096_18500	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3096_18510	COG2246	polysaccharide biosynthetic process
BsBEST3096_18520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3096_18530	COG0586	Pfam SNARE associated Golgi protein
BsBEST3096_18540	COG2404	hydrolase activity, acting on ester bonds
BsBEST3096_18550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3096_18560	COG1024	Enoyl-CoA hydratase
BsBEST3096_18570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3096_18580	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3096_18590	COG0439	Biotin carboxylase
BsBEST3096_18600	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3096_18610	COG1960	acyl-CoA dehydrogenase activity
BsBEST3096_18630	COG1649	PFAM Uncharacterised BCR, COG1649
BsBEST3096_18650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_18650	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3096_18660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_18670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_18680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_18690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_18700	COG2027	D-alanyl-D-alanine carboxypeptidase
BsBEST3096_18710	COG2017	converts alpha-aldose to the beta-anomer
BsBEST3096_18720	COG0534	Mate efflux family protein
BsBEST3096_18740	COG0582	viral genome integration into host DNA
BsBEST3096_18750	COG0166	Belongs to the GPI family
BsBEST3096_18760	COG0405	Gamma-glutamyltransferase
BsBEST3096_18770	COG0583	DNA-binding transcription factor activity
BsBEST3096_18780	COG0604	alcohol dehydrogenase
BsBEST3096_18790	COG0493	'glutamate synthase
BsBEST3096_18800	COG0067	glutamate synthase
BsBEST3096_18800	COG0069	glutamate synthase activity
BsBEST3096_18800	COG0070	glutamate synthase
BsBEST3096_18810	COG0583	DNA-binding transcription factor activity
BsBEST3096_18820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3096_18830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3096_18850	COG0300	oxidoreductase activity
BsBEST3096_18860	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3096_18880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3096_18890	COG2814	Major facilitator Superfamily
BsBEST3096_18900	COG1070	Carbohydrate kinase
BsBEST3096_18910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3096_18920	COG0243	molybdopterin cofactor binding
BsBEST3096_18970	COG0840	transmembrane signaling receptor activity
BsBEST3096_18970	COG5278	phosphoserine phosphatase activity
BsBEST3096_18980	COG2368	4-hydroxyphenylacetate
BsBEST3096_18990	COG4305	rare lipoprotein A
BsBEST3096_19000	COG3619	membrane
BsBEST3096_19010	COG3866	Pectate lyase
BsBEST3096_19020	COG2135	peptidase activity
BsBEST3096_19040	COG2140	Oxalate decarboxylase
BsBEST3096_19060	COG0456	acetyltransferase
BsBEST3096_19090	COG2720	vancomycin resistance protein
BsBEST3096_19110	COG3655	Transcriptional regulator
BsBEST3096_19120	COG3739	integral membrane protein
BsBEST3096_19130	COG0583	DNA-binding transcription factor activity
BsBEST3096_19140	COG0697	spore germination
BsBEST3096_19160	COG0693	protein deglycase activity
BsBEST3096_19170	COG2367	Beta-lactamase
BsBEST3096_19210	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3096_19210	COG3848	Pyruvate phosphate dikinase
BsBEST3096_19220	COG0726	polysaccharide deacetylase
BsBEST3096_19230	COG2314	TM2 domain
BsBEST3096_19240	COG1396	sequence-specific DNA binding
BsBEST3096_19270	COG2135	peptidase activity
BsBEST3096_19330	COG0457	Tetratricopeptide repeat
BsBEST3096_19350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3096_19360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3096_19390	COG5290	Psort location Cytoplasmic, score
BsBEST3096_19430	COG5444	nuclease activity
BsBEST3096_19440	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3096_19450	COG1231	oxidoreductase activity
BsBEST3096_19460	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3096_19470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3096_19480	COG2207	Transcriptional regulator
BsBEST3096_19480	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3096_19490	COG0456	acetyltransferase
BsBEST3096_19500	COG1309	transcriptional regulator
BsBEST3096_19510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3096_19520	COG3708	Transcriptional regulator
BsBEST3096_19530	COG2378	regulation of single-species biofilm formation
BsBEST3096_19550	COG0640	Transcriptional regulator
BsBEST3096_19560	COG0741	lytic transglycosylase activity
BsBEST3096_19570	COG2322	membrane
BsBEST3096_19600	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3096_19610	COG3239	Fatty acid desaturase
BsBEST3096_19620	COG4585	Histidine kinase
BsBEST3096_19630	COG2197	response regulator
BsBEST3096_19640	COG3584	3D domain protein
BsBEST3096_19640	COG1388	LysM domain
BsBEST3096_19650	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3096_19660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3096_19670	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3096_19700	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3096_19750	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_19760	COG1657	PFAM Prenyltransferase squalene oxidase
BsBEST3096_19770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3096_19780	COG0733	neurotransmitter:sodium symporter activity
BsBEST3096_19790	COG0385	Bile acid
BsBEST3096_19800	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3096_19810	COG0567	Dehydrogenase, E1 component
BsBEST3096_19820	COG4548	von Willebrand factor, type A
BsBEST3096_19830	COG0714	Associated with various cellular activities
BsBEST3096_19840	COG2032	superoxide dismutase activity
BsBEST3096_19850	COG0791	NLP P60 protein
BsBEST3096_19850	COG1388	LysM domain
BsBEST3096_19860	COG1819	glycosyl
BsBEST3096_19870	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3096_19880	COG0534	Mate efflux family protein
BsBEST3096_19890	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3096_19900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3096_19910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3096_19930	COG2962	Rard protein
BsBEST3096_19960	COG2610	gluconate transmembrane transporter activity
BsBEST3096_19970	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3096_19980	COG1733	regulation of RNA biosynthetic process
BsBEST3096_19990	COG0778	Nitroreductase
BsBEST3096_20000	COG0400	carboxylic ester hydrolase activity
BsBEST3096_20010	COG0346	lactoylglutathione lyase activity
BsBEST3096_20030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3096_20040	COG0793	Belongs to the peptidase S41A family
BsBEST3096_20040	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_20050	COG2226	methyltransferase
BsBEST3096_20070	COG1876	peptidase activity
BsBEST3096_20080	COG0813	purine-nucleoside phosphorylase activity
BsBEST3096_20110	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3096_20150	COG4479	Belongs to the UPF0346 family
BsBEST3096_20170	COG1509	lysine 2,3-aminomutase activity
BsBEST3096_20180	COG0456	acetyltransferase
BsBEST3096_20190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3096_20200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3096_20210	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3096_20220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3096_20250	COG0456	acetyltransferase
BsBEST3096_20260	COG0463	Glycosyl transferase, family 2
BsBEST3096_20290	COG4641	Protein conserved in bacteria
BsBEST3096_20300	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BsBEST3096_20310	COG1086	Polysaccharide biosynthesis protein
BsBEST3096_20330	COG3331	DNA recombination
BsBEST3096_20420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3096_20480	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BsBEST3096_20490	COG0756	dUTP diphosphatase activity
BsBEST3096_20500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_20510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3096_20530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3096_20550	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3096_20550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3096_20560	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3096_20560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3096_20570	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3096_20750	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3096_20770	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BsBEST3096_20780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3096_20830	COG3584	3D domain protein
BsBEST3096_20840	COG0587	DNA-directed DNA polymerase activity
BsBEST3096_20850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3096_20860	COG0358	DNA primase activity
BsBEST3096_20870	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3096_20890	COG2887	Belongs to the helicase family. UvrD subfamily
BsBEST3096_20950	COG3420	alginic acid biosynthetic process
BsBEST3096_20950	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3096_20960	COG4195	phage-related replication protein
BsBEST3096_20990	COG2135	peptidase activity
BsBEST3096_21000	COG1793	dna ligase
BsBEST3096_21100	COG4474	Belongs to the UPF0398 family
BsBEST3096_21120	COG1388	LysM domain
BsBEST3096_21160	COG3645	SOS response
BsBEST3096_21160	COG3646	Phage regulatory protein
BsBEST3096_21270	COG3655	Transcriptional regulator
BsBEST3096_21300	COG0582	viral genome integration into host DNA
BsBEST3096_21460	COG3655	Transcriptional regulator
BsBEST3096_21530	COG1395	domain, Protein
BsBEST3096_21570	COG0776	regulation of translation
BsBEST3096_21630	COG4373	Mu-like prophage FluMu protein gp28
BsBEST3096_21830	COG0582	viral genome integration into host DNA
BsBEST3096_21890	COG0741	lytic transglycosylase activity
BsBEST3096_21890	COG1196	nuclear chromosome segregation
BsBEST3096_21890	COG0739	heme binding
BsBEST3096_21910	COG2433	Pfam Transposase IS66
BsBEST3096_21930	COG4632	Exopolysaccharide biosynthesis protein
BsBEST3096_21930	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3096_21960	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_21990	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3096_22000	COG0463	Glycosyl transferase, family 2
BsBEST3096_22010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_22020	COG3271	cysteine-type peptidase activity
BsBEST3096_22020	COG2274	protein secretion by the type I secretion system
BsBEST3096_22050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3096_22100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3096_22130	COG5444	nuclease activity
BsBEST3096_22140	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3096_22160	COG1525	nuclease
BsBEST3096_22180	COG2746	aminoglycoside 3-N-acetyltransferase activity
BsBEST3096_22230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3096_22240	COG1086	Polysaccharide biosynthesis protein
BsBEST3096_22250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3096_22260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3096_22270	COG1846	Transcriptional regulator
BsBEST3096_22280	COG0534	Mate efflux family protein
BsBEST3096_22300	COG4698	Protein conserved in bacteria
BsBEST3096_22310	COG2755	lipolytic protein G-D-S-L family
BsBEST3096_22320	COG1999	signal sequence binding
BsBEST3096_22340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BsBEST3096_22350	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3096_22360	COG1272	protein, Hemolysin III
BsBEST3096_22370	COG0204	Acyl-transferase
BsBEST3096_22380	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3096_22390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3096_22400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3096_22420	COG2136	Putative SAM-dependent methyltransferase
BsBEST3096_22420	COG2521	methyltransferase
BsBEST3096_22440	COG0129	dihydroxy-acid dehydratase activity
BsBEST3096_22450	COG1413	lyase activity
BsBEST3096_22460	COG1418	mRNA catabolic process
BsBEST3096_22470	COG0386	Belongs to the glutathione peroxidase family
BsBEST3096_22480	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BsBEST3096_22490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3096_22500	COG1278	Cold shock
BsBEST3096_22540	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3096_22550	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BsBEST3096_22560	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3096_22580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3096_22610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3096_22620	COG1755	Isoprenylcysteine carboxyl methyltransferase
BsBEST3096_22630	COG3424	synthase
BsBEST3096_22640	COG2233	PERMEase
BsBEST3096_22650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3096_22660	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BsBEST3096_22680	COG0800	Aldolase
BsBEST3096_22690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3096_22700	COG1609	Transcriptional regulator
BsBEST3096_22710	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BsBEST3096_22720	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_22730	COG1199	ATP-dependent helicase activity
BsBEST3096_22750	COG0116	Belongs to the methyltransferase superfamily
BsBEST3096_22770	COG4474	Belongs to the UPF0398 family
BsBEST3096_22780	COG3359	exonuclease
BsBEST3096_22790	COG1111	helicase
BsBEST3096_22790	COG1205	dead DEAH box helicase
BsBEST3096_22800	COG2190	(PTS) system
BsBEST3096_22810	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3096_22870	COG3331	DNA recombination
BsBEST3096_22880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3096_22880	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3096_22900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BsBEST3096_22910	COG3935	DnaD domain protein
BsBEST3096_22920	COG0017	Asparaginyl-tRNA synthetase
BsBEST3096_22930	COG0436	Aminotransferase
BsBEST3096_22940	COG5353	protein conserved in bacteria
BsBEST3096_22960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BsBEST3096_22960	COG1199	ATP-dependent helicase activity
BsBEST3096_22970	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BsBEST3096_22980	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BsBEST3096_22990	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BsBEST3096_23000	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BsBEST3096_23000	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BsBEST3096_23010	COG0617	tRNA 3'-terminal CCA addition
BsBEST3096_23020	COG0438	transferase activity, transferring glycosyl groups
BsBEST3096_23030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3096_23040	COG1803	Methylglyoxal synthase
BsBEST3096_23050	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BsBEST3096_23060	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3096_23070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3096_23090	COG4347	Protein of unknown function (DUF1405)
BsBEST3096_23100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3096_23100	COG2010	Cytochrome c
BsBEST3096_23110	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3096_23120	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3096_23140	COG5582	Belongs to the UPF0302 family
BsBEST3096_23150	COG0457	Tetratricopeptide repeat
BsBEST3096_23160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BsBEST3096_23170	COG0287	Prephenate dehydrogenase
BsBEST3096_23180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BsBEST3096_23190	COG0159	tryptophan synthase activity
BsBEST3096_23200	COG0133	tryptophan synthase activity
BsBEST3096_23210	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3096_23230	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BsBEST3096_23240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3096_23250	COG4401	Chorismate mutase type I
BsBEST3096_23260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BsBEST3096_23270	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BsBEST3096_23280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BsBEST3096_23290	COG0105	UTP biosynthetic process
BsBEST3096_23300	COG0142	geranyltranstransferase activity
BsBEST3096_23310	COG2226	methyltransferase
BsBEST3096_23320	COG0142	geranyltranstransferase activity
BsBEST3096_23340	COG0302	gtp cyclohydrolase
BsBEST3096_23350	COG0776	regulation of translation
BsBEST3096_23360	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3096_23390	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BsBEST3096_23400	COG1160	GTP binding
BsBEST3096_23450	COG1304	FMN binding
BsBEST3096_23460	COG0539	negative regulation of cytoplasmic translation
BsBEST3096_23470	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BsBEST3096_23490	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BsBEST3096_23500	COG2959	enzyme of heme biosynthesis
BsBEST3096_23510	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_23510	COG3773	Cell wall hydrolase
BsBEST3096_23520	COG2339	peptidase activity
BsBEST3096_23530	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3096_23540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3096_23550	COG4862	establishment of competence for transformation
BsBEST3096_23560	COG1408	metallophosphoesterase
BsBEST3096_23570	COG1388	LysM domain
BsBEST3096_23580	COG1266	CAAX protease self-immunity
BsBEST3096_23590	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3096_23600	COG4955	Helix-turn-helix domain
BsBEST3096_23610	COG1141	Ferredoxin
BsBEST3096_23620	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BsBEST3096_23640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3096_23650	COG0710	3-dehydroquinate dehydratase activity
BsBEST3096_23670	COG1595	DNA-templated transcription, initiation
BsBEST3096_23680	COG5002	protein histidine kinase activity
BsBEST3096_23690	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_23700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3096_23710	COG1333	cytochrome c biogenesis protein
BsBEST3096_23720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_23730	COG1187	pseudouridine synthase activity
BsBEST3096_23740	COG0700	Nucleoside recognition
BsBEST3096_23750	COG2715	membrane protein required for spore maturation
BsBEST3096_23760	COG1686	Belongs to the peptidase S11 family
BsBEST3096_23780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BsBEST3096_23790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BsBEST3096_23800	COG1547	Domain of unknown function (DUF309)
BsBEST3096_23810	COG0456	acetyltransferase
BsBEST3096_23820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BsBEST3096_23830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3096_23830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3096_23840	COG0307	riboflavin synthase, alpha
BsBEST3096_23850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3096_23850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3096_23870	COG0681	Belongs to the peptidase S26 family
BsBEST3096_23890	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BsBEST3096_23920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BsBEST3096_23930	COG4086	secreted protein
BsBEST3096_23940	COG0019	diaminopimelate decarboxylase activity
BsBEST3096_23950	COG0697	spore germination
BsBEST3096_23980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3096_24020	COG1191	sigma factor activity
BsBEST3096_24030	COG2172	sigma factor antagonist activity
BsBEST3096_24040	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3096_24050	COG1686	Belongs to the peptidase S11 family
BsBEST3096_24060	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BsBEST3096_24070	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BsBEST3096_24080	COG4974	Belongs to the 'phage' integrase family
BsBEST3096_24100	COG0735	belongs to the Fur family
BsBEST3096_24110	COG1300	Membrane
BsBEST3096_24130	COG0281	malic enzyme
BsBEST3096_24140	COG1757	Na H antiporter
BsBEST3096_24150	COG1027	Aspartate ammonia-lyase
BsBEST3096_24160	COG0252	asparaginase activity
BsBEST3096_24170	COG1396	sequence-specific DNA binding
BsBEST3096_24180	COG1379	DNA repair
BsBEST3096_24190	COG0494	nUDIX hydrolase
BsBEST3096_24210	COG0667	Aldo Keto reductase
BsBEST3096_24230	COG1073	alpha beta
BsBEST3096_24250	COG4918	Iron-sulphur cluster biosynthesis
BsBEST3096_24260	COG0456	acetyltransferase
BsBEST3096_24260	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BsBEST3096_24270	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3096_24280	COG0456	acetyltransferase
BsBEST3096_24300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3096_24320	COG2211	Major facilitator Superfamily
BsBEST3096_24340	COG0346	lactoylglutathione lyase activity
BsBEST3096_24350	COG1072	(Pantothenic acid kinase))
BsBEST3096_24360	COG3048	D-serine ammonia-lyase activity
BsBEST3096_24370	COG0300	oxidoreductase activity
BsBEST3096_24380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3096_24390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3096_24400	COG4187	Peptidase family M20/M25/M40
BsBEST3096_24410	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3096_24420	COG0596	Alpha beta hydrolase
BsBEST3096_24430	COG1234	tRNA 3'-trailer cleavage
BsBEST3096_24440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BsBEST3096_24450	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3096_24460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3096_24480	COG0706	membrane insertase activity
BsBEST3096_24490	COG3361	conserved protein (COG2071)
BsBEST3096_24500	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3096_24510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3096_24520	COG0346	lactoylglutathione lyase activity
BsBEST3096_24530	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3096_24540	COG4129	membrane
BsBEST3096_24550	COG1126	abc transporter atp-binding protein
BsBEST3096_24560	COG0765	amino acid transport
BsBEST3096_24570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3096_24590	COG1597	lipid kinase activity
BsBEST3096_24600	COG2814	Major facilitator Superfamily
BsBEST3096_24610	COG0789	Transcriptional regulator
BsBEST3096_24610	COG4978	Transcriptional regulator
BsBEST3096_24620	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3096_24630	COG0022	dehydrogenase e1 component
BsBEST3096_24640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3096_24650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3096_24660	COG3426	butyrate kinase activity
BsBEST3096_24670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3096_24680	COG0280	phosphate acetyltransferase
BsBEST3096_24690	COG3290	protein histidine kinase activity
BsBEST3096_24690	COG3829	transcription factor binding
BsBEST3096_24710	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BsBEST3096_24720	COG2079	MmgE PrpD family protein
BsBEST3096_24730	COG0372	Belongs to the citrate synthase family
BsBEST3096_24740	COG1960	acyl-CoA dehydrogenase activity
BsBEST3096_24750	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3096_24760	COG0183	Belongs to the thiolase family
BsBEST3096_24770	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3096_24780	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_24800	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3096_24810	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_24820	COG0750	zinc metalloprotease
BsBEST3096_24830	COG0497	DNA recombination
BsBEST3096_24840	COG1438	arginine binding
BsBEST3096_24850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BsBEST3096_24860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BsBEST3096_24870	COG0142	geranyltranstransferase activity
BsBEST3096_24880	COG1722	exodeoxyribonuclease VII activity
BsBEST3096_24890	COG1570	exodeoxyribonuclease VII activity
BsBEST3096_24900	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BsBEST3096_24910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3096_24920	COG1302	Protein conserved in bacteria
BsBEST3096_24930	COG0439	Biotin carboxylase
BsBEST3096_24940	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3096_25020	COG3854	ATPases associated with a variety of cellular activities
BsBEST3096_25040	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BsBEST3096_25050	COG0006	proline dipeptidase activity
BsBEST3096_25060	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BsBEST3096_25080	COG3872	metal-dependent enzyme
BsBEST3096_25100	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3096_25110	COG1321	iron dependent repressor
BsBEST3096_25120	COG0095	Lipoate-protein ligase
BsBEST3096_25130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3096_25140	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3096_25150	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3096_25160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BsBEST3096_25170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3096_25200	COG1396	sequence-specific DNA binding
BsBEST3096_25220	COG0681	Belongs to the peptidase S26 family
BsBEST3096_25270	COG4940	Competence protein ComGF
BsBEST3096_25290	COG4970	Tfp pilus assembly protein FimT
BsBEST3096_25300	COG4537	Required for transformation and DNA binding
BsBEST3096_25310	COG1459	type II secretion system
BsBEST3096_25320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BsBEST3096_25330	COG0598	Magnesium transport protein CorA
BsBEST3096_25340	COG1253	flavin adenine dinucleotide binding
BsBEST3096_25350	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3096_25360	COG1393	Belongs to the ArsC family
BsBEST3096_25380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3096_25400	COG0011	TIGRFAM Protein of
BsBEST3096_25420	COG2866	Carboxypeptidase
BsBEST3096_25430	COG1368	sulfuric ester hydrolase activity
BsBEST3096_25440	COG1940	carbohydrate kinase activity
BsBEST3096_25450	COG4483	Protein conserved in bacteria
BsBEST3096_25460	COG0457	Tetratricopeptide repeat
BsBEST3096_25460	COG0705	Rhomboid family
BsBEST3096_25480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BsBEST3096_25500	COG0438	transferase activity, transferring glycosyl groups
BsBEST3096_25530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3096_25540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3096_25550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3096_25560	COG0581	inorganic phosphate transmembrane transporter activity
BsBEST3096_25570	COG0573	inorganic phosphate transmembrane transporter activity
BsBEST3096_25580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BsBEST3096_25590	COG0768	penicillin binding
BsBEST3096_25600	COG0477	Major facilitator Superfamily
BsBEST3096_25610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3096_25620	COG2839	Protein conserved in bacteria
BsBEST3096_25630	COG5521	maltodextrose utilization protein MalA
BsBEST3096_25650	COG1388	LysM domain
BsBEST3096_25660	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BsBEST3096_25670	COG4709	membrane
BsBEST3096_25680	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BsBEST3096_25690	COG0735	belongs to the Fur family
BsBEST3096_25700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3096_25720	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BsBEST3096_25730	COG0513	Belongs to the DEAD box helicase family
BsBEST3096_25750	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BsBEST3096_25760	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BsBEST3096_25770	COG2384	SAM-dependent methyltransferase
BsBEST3096_25780	COG2010	Cytochrome c
BsBEST3096_25790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BsBEST3096_25800	COG0358	DNA primase activity
BsBEST3096_25810	COG1671	Belongs to the UPF0178 family
BsBEST3096_25820	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BsBEST3096_25830	COG0517	IMP dehydrogenase activity
BsBEST3096_25840	COG0751	glycine-tRNA ligase activity
BsBEST3096_25850	COG0752	glycyl-tRNA synthetase alpha subunit
BsBEST3096_25860	COG1381	Involved in DNA repair and RecF pathway recombination
BsBEST3096_25880	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BsBEST3096_25890	COG0295	cytidine deaminase activity
BsBEST3096_25900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BsBEST3096_25910	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BsBEST3096_25920	COG1480	7TM receptor with intracellular HD hydrolase
BsBEST3096_25930	COG1702	phosphate starvation-inducible protein PhoH
BsBEST3096_25940	COG0561	phosphatase activity
BsBEST3096_25970	COG4864	UPF0365 protein
BsBEST3096_25980	COG1030	water channel activity
BsBEST3096_25990	COG1610	YqeY-like protein
BsBEST3096_26010	COG1283	sodium-dependent phosphate transmembrane transporter activity
BsBEST3096_26020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3096_26030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BsBEST3096_26040	COG2264	protein methyltransferase activity
BsBEST3096_26050	COG0484	heat shock protein binding
BsBEST3096_26060	COG0443	Heat shock 70 kDa protein
BsBEST3096_26070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BsBEST3096_26080	COG1420	regulation of RNA biosynthetic process
BsBEST3096_26090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3096_26100	COG0481	GTPase activity
BsBEST3096_26120	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_26130	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BsBEST3096_26150	COG0268	Binds directly to 16S ribosomal RNA
BsBEST3096_26160	COG1466	dna polymerase III delta subunit
BsBEST3096_26180	COG2333	competence protein COMEC
BsBEST3096_26180	COG0658	competence protein
BsBEST3096_26200	COG2131	deaminase
BsBEST3096_26210	COG1555	photosystem II stabilization
BsBEST3096_26210	COG1596	polysaccharide export
BsBEST3096_26220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3096_26230	COG2226	methyltransferase
BsBEST3096_26240	COG0799	negative regulation of ribosome biogenesis
BsBEST3096_26250	COG1713	HD superfamily hydrolase involved in NAD metabolism
BsBEST3096_26260	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BsBEST3096_26270	COG1534	Rna-binding protein
BsBEST3096_26280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BsBEST3096_26290	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3096_26300	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BsBEST3096_26310	COG2755	lipolytic protein G-D-S-L family
BsBEST3096_26320	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_26320	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_26330	COG0398	Pfam SNARE associated Golgi protein
BsBEST3096_26340	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BsBEST3096_26360	COG3209	COG3209 Rhs family protein
BsBEST3096_26380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3096_26400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3096_26410	COG0798	PFAM Bile acid sodium symporter
BsBEST3096_26420	COG0346	lactoylglutathione lyase activity
BsBEST3096_26430	COG0640	Transcriptional regulator
BsBEST3096_26440	COG3403	YqcI/YcgG family
BsBEST3096_26450	COG0457	Tetratricopeptide repeat
BsBEST3096_26480	COG5444	nuclease activity
BsBEST3096_26530	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_26530	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_26540	COG4824	toxin secretion phage lysis holin
BsBEST3096_26600	COG3778	Protein conserved in bacteria
BsBEST3096_26610	COG3299	homolog of phage Mu protein gp47
BsBEST3096_26620	COG3628	GPW Gp25 family protein
BsBEST3096_26640	COG4193	domain, Protein
BsBEST3096_26650	COG1652	LysM domain
BsBEST3096_26660	COG3953	SLT domain
BsBEST3096_26660	COG5280	Phage tail tape measure protein TP901
BsBEST3096_26790	COG4653	Phage capsid family
BsBEST3096_26800	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3096_26820	COG2369	cell adhesion
BsBEST3096_26830	COG5518	Phage portal protein
BsBEST3096_26840	COG1783	phage Terminase large subunit
BsBEST3096_26850	COG5484	DNA packaging
BsBEST3096_26870	COG3677	Transposase
BsBEST3096_26900	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BsBEST3096_26920	COG1484	DNA-dependent DNA replication
BsBEST3096_26930	COG3935	DnaD domain protein
BsBEST3096_26940	COG3723	Recombinational DNA repair protein, rece pathway
BsBEST3096_26950	COG5377	YqaJ viral recombinase family
BsBEST3096_27010	COG1476	TRANSCRIPTIONal
BsBEST3096_27020	COG3620	sequence-specific DNA binding
BsBEST3096_27040	COG0563	adenylate kinase activity
BsBEST3096_27050	COG2856	Zn peptidase
BsBEST3096_27070	COG3223	Belongs to the PsiE family
BsBEST3096_27080	COG0642	Histidine kinase
BsBEST3096_27080	COG5002	protein histidine kinase activity
BsBEST3096_27090	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_27100	COG2311	Membrane
BsBEST3096_27110	COG0454	-acetyltransferase
BsBEST3096_27120	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3096_27140	COG0730	response to heat
BsBEST3096_27150	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3096_27160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3096_27160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3096_27170	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3096_27170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3096_27180	COG2210	Belongs to the sulfur carrier protein TusA family
BsBEST3096_27190	COG1937	Protein conserved in bacteria
BsBEST3096_27220	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3096_27240	COG4978	Transcriptional regulator
BsBEST3096_27240	COG0789	Transcriptional regulator
BsBEST3096_27250	COG2814	Major facilitator Superfamily
BsBEST3096_27260	COG0456	acetyltransferase
BsBEST3096_27270	COG1253	flavin adenine dinucleotide binding
BsBEST3096_27290	COG0697	spore germination
BsBEST3096_27300	COG0583	DNA-binding transcription factor activity
BsBEST3096_27310	COG2072	flavoprotein involved in K transport
BsBEST3096_27320	COG1230	cation diffusion facilitator family transporter
BsBEST3096_27330	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3096_27340	COG0583	DNA-binding transcription factor activity
BsBEST3096_27360	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3096_27370	COG1687	branched-chain amino acid
BsBEST3096_27380	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BsBEST3096_27390	COG1522	sequence-specific DNA binding
BsBEST3096_27400	COG2732	(Barnase) inhibitor
BsBEST3096_27410	COG2124	cytochrome p450
BsBEST3096_27440	COG1335	isochorismatase
BsBEST3096_27460	COG2318	DinB family
BsBEST3096_27480	COG2070	2-Nitropropane dioxygenase
BsBEST3096_27510	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3096_27540	COG3443	Belongs to the bacterial solute-binding protein 9 family
BsBEST3096_27550	COG1595	DNA-templated transcription, initiation
BsBEST3096_27560	COG0667	Aldo Keto reductase
BsBEST3096_27570	COG2851	Citrate transporter
BsBEST3096_27580	COG0583	DNA-binding transcription factor activity
BsBEST3096_27590	COG2828	Protein conserved in bacteria
BsBEST3096_27610	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_27620	COG5566	PFAM Mor transcription activator
BsBEST3096_27630	COG0596	Alpha beta hydrolase
BsBEST3096_27640	COG4991	sh3 domain protein
BsBEST3096_27650	COG4991	sh3 domain protein
BsBEST3096_27660	COG0346	lactoylglutathione lyase activity
BsBEST3096_27680	COG5577	PFAM Coat F domain
BsBEST3096_27690	COG1063	alcohol dehydrogenase
BsBEST3096_27710	COG5577	PFAM Coat F domain
BsBEST3096_27720	COG0789	Transcriptional regulator
BsBEST3096_27740	COG1064	alcohol dehydrogenase
BsBEST3096_27750	COG0693	protein deglycase activity
BsBEST3096_27760	COG1621	beta-fructofuranosidase activity
BsBEST3096_27780	COG3716	PTS system mannose fructose sorbose family IID component
BsBEST3096_27790	COG3715	PTS system
BsBEST3096_27800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3096_27810	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3096_27820	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3096_27820	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BsBEST3096_27830	COG1113	amino acid transport
BsBEST3096_27840	COG1280	lysine exporter protein (LysE YggA)
BsBEST3096_27850	COG1378	Sugar-specific transcriptional regulator TrmB
BsBEST3096_27860	COG1595	DNA-templated transcription, initiation
BsBEST3096_27880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BsBEST3096_27880	COG2755	lipolytic protein G-D-S-L family
BsBEST3096_27900	COG2124	cytochrome p450
BsBEST3096_27900	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3096_27910	COG1309	transcriptional regulator
BsBEST3096_27920	COG2226	methyltransferase
BsBEST3096_27940	COG2116	formate transmembrane transporter activity
BsBEST3096_27950	COG5609	conserved protein (DUF2294)
BsBEST3096_27960	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3096_27970	COG2427	Protein of unknown function (DUF1641)
BsBEST3096_27990	COG0626	cystathionine gamma-synthase activity
BsBEST3096_28000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3096_28010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BsBEST3096_28020	COG2226	methyltransferase
BsBEST3096_28050	COG0768	penicillin binding
BsBEST3096_28060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BsBEST3096_28070	COG0572	uridine kinase
BsBEST3096_28080	COG0826	peptidase U32
BsBEST3096_28090	COG0826	peptidase U32
BsBEST3096_28100	COG4122	O-methyltransferase activity
BsBEST3096_28110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3096_28120	COG3906	Belongs to the UPF0473 family
BsBEST3096_28130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BsBEST3096_28140	COG4472	Bacterial protein of unknown function (DUF965)
BsBEST3096_28150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BsBEST3096_28160	COG0628	permease
BsBEST3096_28170	COG1126	abc transporter atp-binding protein
BsBEST3096_28180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3096_28190	COG0765	amino acid transport
BsBEST3096_28200	COG0765	amino acid transport
BsBEST3096_28230	COG3881	PFAM PRC-barrel domain
BsBEST3096_28240	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BsBEST3096_28250	COG0457	Tetratricopeptide repeat
BsBEST3096_28260	COG0482	sulfurtransferase activity
BsBEST3096_28270	COG1104	cysteine desulfurase activity
BsBEST3096_28280	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3096_28290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BsBEST3096_28300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BsBEST3096_28310	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BsBEST3096_28320	COG0124	histidyl-tRNA synthetase
BsBEST3096_28340	COG3103	Sh3 type 3 domain protein
BsBEST3096_28340	COG4991	sh3 domain protein
BsBEST3096_28340	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_28350	COG1490	D-aminoacyl-tRNA deacylase activity
BsBEST3096_28360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BsBEST3096_28370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3096_28380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3096_28380	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BsBEST3096_28390	COG5416	Lipopolysaccharide assembly protein A domain
BsBEST3096_28400	COG0490	domain, Protein
BsBEST3096_28410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3096_28410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3096_28430	COG2244	polysaccharide biosynthetic process
BsBEST3096_28440	COG2323	membrane
BsBEST3096_28460	COG1862	Preprotein translocase
BsBEST3096_28470	COG0343	queuine tRNA-ribosyltransferase activity
BsBEST3096_28480	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BsBEST3096_28500	COG2255	four-way junction helicase activity
BsBEST3096_28510	COG0632	four-way junction helicase activity
BsBEST3096_28530	COG2814	Major facilitator Superfamily
BsBEST3096_28540	COG0673	inositol 2-dehydrogenase activity
BsBEST3096_28550	COG2112	serine threonine protein kinase
BsBEST3096_28590	COG1115	amino acid carrier protein
BsBEST3096_28600	COG0217	transcriptional regulatory protein
BsBEST3096_28620	COG1388	LysM domain
BsBEST3096_28630	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BsBEST3096_28640	COG0157	Belongs to the NadC ModD family
BsBEST3096_28650	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BsBEST3096_28660	COG1104	cysteine desulfurase activity
BsBEST3096_28670	COG1827	regulation of RNA biosynthetic process
BsBEST3096_28680	COG0077	Prephenate dehydratase
BsBEST3096_28690	COG4492	Belongs to the UPF0735 family
BsBEST3096_28700	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BsBEST3096_28710	COG3290	protein histidine kinase activity
BsBEST3096_28720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BsBEST3096_28730	COG2868	ribosomal protein
BsBEST3096_28740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BsBEST3096_28750	COG1994	Peptidase M50
BsBEST3096_28760	COG0739	heme binding
BsBEST3096_28770	COG2894	cell division
BsBEST3096_28780	COG0850	regulation of cytokinetic process
BsBEST3096_28790	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BsBEST3096_28810	COG1077	Cell shape determining protein MreB Mrl
BsBEST3096_28820	COG2003	Belongs to the UPF0758 family
BsBEST3096_28830	COG0424	maF-like protein
BsBEST3096_28850	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BsBEST3096_28860	COG0285	dihydrofolate synthase activity
BsBEST3096_28870	COG0525	valine-tRNA ligase activity
BsBEST3096_28890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3096_28900	COG1388	LysM domain
BsBEST3096_28910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3096_28920	COG0113	porphobilinogen synthase activity
BsBEST3096_28930	COG1587	Uroporphyrinogen-III synthase
BsBEST3096_28940	COG0181	hydroxymethylbilane synthase activity
BsBEST3096_28950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3096_28960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BsBEST3096_28980	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BsBEST3096_28990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BsBEST3096_29000	COG0470	DNA polymerase III
BsBEST3096_29000	COG1067	ATP-dependent peptidase activity
BsBEST3096_29010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BsBEST3096_29020	COG0544	peptidyl-prolyl cis-trans isomerase activity
BsBEST3096_29030	COG0457	Tetratricopeptide repeat
BsBEST3096_29030	COG1477	protein flavinylation
BsBEST3096_29040	COG0066	3-isopropylmalate dehydratase activity
BsBEST3096_29050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BsBEST3096_29060	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3096_29070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3096_29080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BsBEST3096_29090	COG0440	acetolactate synthase activity
BsBEST3096_29100	COG0028	Belongs to the TPP enzyme family
BsBEST3096_29120	COG0454	-acetyltransferase
BsBEST3096_29130	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BsBEST3096_29140	COG0622	Phosphoesterase
BsBEST3096_29150	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BsBEST3096_29160	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BsBEST3096_29170	COG5401	PFAM Sporulation and spore germination
BsBEST3096_29180	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3096_29190	COG1846	Transcriptional regulator
BsBEST3096_29200	COG2197	response regulator
BsBEST3096_29210	COG0824	Thioesterase
BsBEST3096_29220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BsBEST3096_29230	COG1053	succinate dehydrogenase
BsBEST3096_29240	COG2009	succinate dehydrogenase
BsBEST3096_29250	COG1719	4-vinyl reductase, 4VR
BsBEST3096_29260	COG0527	aspartate kinase activity
BsBEST3096_29270	COG0322	excinuclease ABC activity
BsBEST3096_29280	COG3118	belongs to the thioredoxin family
BsBEST3096_29290	COG3534	alpha-L-arabinofuranosidase
BsBEST3096_29310	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BsBEST3096_29320	COG2086	electron transfer activity
BsBEST3096_29330	COG1024	Enoyl-CoA hydratase
BsBEST3096_29340	COG1309	transcriptional regulator
BsBEST3096_29350	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3096_29360	COG3766	membrane
BsBEST3096_29370	COG1193	negative regulation of DNA recombination
BsBEST3096_29380	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3096_29380	COG1796	DNA polymerase
BsBEST3096_29390	COG1286	toxin biosynthetic process
BsBEST3096_29400	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BsBEST3096_29410	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3096_29420	COG0072	phenylalanine-tRNA ligase activity
BsBEST3096_29420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3096_29430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BsBEST3096_29440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3096_29460	COG3835	regulator
BsBEST3096_29470	COG0277	FAD linked oxidase domain protein
BsBEST3096_29480	COG0247	lactate metabolic process
BsBEST3096_29490	COG0346	lactoylglutathione lyase activity
BsBEST3096_29510	COG1966	Carbon starvation protein
BsBEST3096_29520	COG3534	alpha-L-arabinofuranosidase
BsBEST3096_29530	COG0395	ABC-type sugar transport system, permease component
BsBEST3096_29540	COG1175	transmembrane transport
BsBEST3096_29550	COG1653	transport
BsBEST3096_29560	COG0371	Dehydrogenase
BsBEST3096_29570	COG0647	UMP catabolic process
BsBEST3096_29580	COG0235	Class ii aldolase
BsBEST3096_29590	COG1069	ribulokinase activity
BsBEST3096_29600	COG2160	L-arabinose isomerase activity
BsBEST3096_29610	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3096_29620	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3096_29630	COG1363	Peptidase, m42
BsBEST3096_29650	COG3326	Membrane
BsBEST3096_29660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BsBEST3096_29670	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BsBEST3096_29680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BsBEST3096_29700	COG1346	cytolysis
BsBEST3096_29710	COG1380	Effector of murein hydrolase LrgA
BsBEST3096_29720	COG3279	Response regulator of the LytR AlgR family
BsBEST3096_29730	COG3275	phosphorelay sensor kinase activity
BsBEST3096_29740	COG1011	Hydrolase
BsBEST3096_29750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3096_29770	COG0398	Pfam SNARE associated Golgi protein
BsBEST3096_29780	COG1484	DNA-dependent DNA replication
BsBEST3096_29790	COG3611	Membrane attachment protein
BsBEST3096_29800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BsBEST3096_29810	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BsBEST3096_29820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3096_29830	COG1733	regulation of RNA biosynthetic process
BsBEST3096_29840	COG2814	Major facilitator Superfamily
BsBEST3096_29850	COG0656	L-ascorbic acid biosynthetic process
BsBEST3096_29860	COG0237	dephospho-CoA kinase activity
BsBEST3096_29870	COG1971	Probably functions as a manganese efflux pump
BsBEST3096_29880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BsBEST3096_29890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3096_29890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3096_29900	COG5002	protein histidine kinase activity
BsBEST3096_29910	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_29920	COG0039	L-malate dehydrogenase activity
BsBEST3096_29930	COG0538	isocitrate dehydrogenase activity
BsBEST3096_29940	COG0372	Belongs to the citrate synthase family
BsBEST3096_29950	COG2707	UPF0756 membrane protein
BsBEST3096_29960	COG0628	permease
BsBEST3096_29970	COG3030	protein affecting phage T7 exclusion by the F plasmid
BsBEST3096_29980	COG0469	pyruvate kinase activity
BsBEST3096_29990	COG0205	6-phosphofructokinase activity
BsBEST3096_30000	COG0825	malonyl-CoA metabolic process
BsBEST3096_30010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BsBEST3096_30020	COG0281	malic enzyme
BsBEST3096_30030	COG0587	DNA-directed DNA polymerase activity
BsBEST3096_30070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BsBEST3096_30090	COG4109	DRTGG domain
BsBEST3096_30100	COG0730	response to heat
BsBEST3096_30110	COG1473	amidohydrolase
BsBEST3096_30120	COG0196	riboflavin kinase activity
BsBEST3096_30130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3096_30140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BsBEST3096_30150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3096_30160	COG1126	abc transporter atp-binding protein
BsBEST3096_30170	COG0765	amino acid transport
BsBEST3096_30180	COG0765	amino acid transport
BsBEST3096_30190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3096_30200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3096_30210	COG0454	-acetyltransferase
BsBEST3096_30220	COG0583	DNA-binding transcription factor activity
BsBEST3096_30230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3096_30240	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_30260	COG0165	Argininosuccinate lyase
BsBEST3096_30270	COG0137	argininosuccinate synthase activity
BsBEST3096_30280	COG0521	Mo-molybdopterin cofactor biosynthetic process
BsBEST3096_30290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BsBEST3096_30300	COG0827	DNA restriction-modification system
BsBEST3096_30310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BsBEST3096_30320	COG3874	Sporulation protein YtfJ
BsBEST3096_30340	COG1714	RDD family
BsBEST3096_30350	COG0616	signal peptide processing
BsBEST3096_30360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3096_30370	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BsBEST3096_30380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3096_30400	COG0301	tRNA thio-modification
BsBEST3096_30410	COG1104	cysteine desulfurase activity
BsBEST3096_30420	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3096_30430	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BsBEST3096_30440	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3096_30450	COG1309	transcriptional regulator
BsBEST3096_30460	COG1956	GAF domain-containing protein
BsBEST3096_30470	COG2199	diguanylate cyclase activity
BsBEST3096_30470	COG2203	Gaf domain
BsBEST3096_30480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BsBEST3096_30500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3096_30510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3096_30520	COG0454	-acetyltransferase
BsBEST3096_30530	COG0517	IMP dehydrogenase activity
BsBEST3096_30540	COG0123	including yeast histone deacetylase and acetoin utilization protein
BsBEST3096_30550	COG1360	Flagellar Motor Protein
BsBEST3096_30560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3096_30570	COG1609	Transcriptional regulator
BsBEST3096_30580	COG1605	Chorismate mutase
BsBEST3096_30580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BsBEST3096_30590	COG3118	belongs to the thioredoxin family
BsBEST3096_30600	COG4980	gas vesicle protein
BsBEST3096_30610	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3096_30620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BsBEST3096_30630	COG1674	ftsk spoiiie
BsBEST3096_30640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3096_30650	COG4848	Belongs to the UPF0354 family
BsBEST3096_30660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_30680	COG1363	Peptidase, m42
BsBEST3096_30690	COG5584	Small secreted protein
BsBEST3096_30700	COG0281	malic enzyme
BsBEST3096_30710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3096_30720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BsBEST3096_30740	COG0510	thiamine kinase activity
BsBEST3096_30750	COG1523	belongs to the glycosyl hydrolase 13 family
BsBEST3096_30760	COG1597	lipid kinase activity
BsBEST3096_30780	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3096_30790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3096_30800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3096_30810	COG2252	PERMEase
BsBEST3096_30820	COG4473	ABC transporter
BsBEST3096_30830	COG1131	(ABC) transporter
BsBEST3096_30850	COG1349	DNA-binding transcription factor activity
BsBEST3096_30860	COG1187	pseudouridine synthase activity
BsBEST3096_30870	COG2244	polysaccharide biosynthetic process
BsBEST3096_30880	COG2081	HI0933 family
BsBEST3096_30890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BsBEST3096_30910	COG5578	integral membrane protein
BsBEST3096_30920	COG0673	inositol 2-dehydrogenase activity
BsBEST3096_30930	COG1653	transport
BsBEST3096_30940	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3096_30950	COG4209	transmembrane transport
BsBEST3096_30960	COG2207	Transcriptional regulator
BsBEST3096_30970	COG2207	Transcriptional regulator
BsBEST3096_30980	COG1653	transport
BsBEST3096_30990	COG0395	ABC-type sugar transport system, permease component
BsBEST3096_31000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3096_31010	COG2124	cytochrome p450
BsBEST3096_31020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BsBEST3096_31030	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BsBEST3096_31040	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3096_31050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3096_31060	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BsBEST3096_31070	COG1073	alpha beta
BsBEST3096_31080	COG1609	Transcriptional regulator
BsBEST3096_31090	COG1653	transport
BsBEST3096_31100	COG1175	transmembrane transport
BsBEST3096_31110	COG0395	ABC-type sugar transport system, permease component
BsBEST3096_31120	COG1486	melibiose metabolic process
BsBEST3096_31130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3096_31140	COG0495	leucyl-tRNA aminoacylation
BsBEST3096_31160	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3096_31160	COG2202	Pas domain
BsBEST3096_31170	COG2814	Major facilitator Superfamily
BsBEST3096_31180	COG2433	Pfam Transposase IS66
BsBEST3096_31190	COG0577	efflux transmembrane transporter activity
BsBEST3096_31200	COG1136	(ABC) transporter
BsBEST3096_31210	COG2205	protein histidine kinase activity
BsBEST3096_31220	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_31230	COG0577	efflux transmembrane transporter activity
BsBEST3096_31240	COG1136	(ABC) transporter
BsBEST3096_31270	COG1131	(ABC) transporter
BsBEST3096_31280	COG1725	Transcriptional regulator
BsBEST3096_31300	COG1242	4 iron, 4 sulfur cluster binding
BsBEST3096_31310	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BsBEST3096_31330	COG2267	carboxylic ester hydrolase activity
BsBEST3096_31340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BsBEST3096_31350	COG1113	amino acid transport
BsBEST3096_31360	COG0367	asparagine synthase
BsBEST3096_31370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BsBEST3096_31380	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BsBEST3096_31400	COG1506	peptidase
BsBEST3096_31410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3096_31420	COG1116	anion transmembrane transporter activity
BsBEST3096_31430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3096_31440	COG0494	nUDIX hydrolase
BsBEST3096_31450	COG4824	toxin secretion phage lysis holin
BsBEST3096_31460	COG0783	Belongs to the Dps family
BsBEST3096_31490	COG1854	S-ribosylhomocysteine lyase activity
BsBEST3096_31500	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BsBEST3096_31510	COG0288	reversible hydration of carbon dioxide
BsBEST3096_31520	COG0254	rRNA binding
BsBEST3096_31530	COG1271	oxidase subunit
BsBEST3096_31540	COG1294	oxidase, subunit
BsBEST3096_31560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3096_31570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3096_31570	COG1321	iron dependent repressor
BsBEST3096_31580	COG1121	(ABC) transporter
BsBEST3096_31590	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3096_31600	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3096_31610	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3096_31620	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BsBEST3096_31630	COG0596	Alpha beta hydrolase
BsBEST3096_31640	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BsBEST3096_31650	COG1169	isochorismate synthase
BsBEST3096_31660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3096_31670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3096_31680	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3096_31690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3096_31700	COG0438	transferase activity, transferring glycosyl groups
BsBEST3096_31720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3096_31730	COG0438	transferase activity, transferring glycosyl groups
BsBEST3096_31740	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3096_31750	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BsBEST3096_31760	COG0058	SHG alpha-glucan phosphorylase activity
BsBEST3096_31770	COG0297	glycogen (starch) synthase activity
BsBEST3096_31780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3096_31790	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3096_31800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BsBEST3096_31810	COG3859	Proton-coupled thiamine transporter YuaJ
BsBEST3096_31820	COG1247	-acetyltransferase
BsBEST3096_31830	COG2268	Band 7 protein
BsBEST3096_31840	COG1585	Membrane protein implicated in regulation of membrane protease activity
BsBEST3096_31850	COG2318	DinB family
BsBEST3096_31870	COG1454	alcohol dehydrogenase
BsBEST3096_31880	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_31890	COG1510	regulation of RNA biosynthetic process
BsBEST3096_31910	COG0569	domain protein
BsBEST3096_31920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3096_31930	COG4682	membrane
BsBEST3096_31940	COG1705	Flagellar rod assembly protein muramidase FlgJ
BsBEST3096_31950	COG0477	Major facilitator Superfamily
BsBEST3096_31960	COG5553	Cysteine dioxygenase type I
BsBEST3096_31970	COG1968	undecaprenyl-diphosphatase activity
BsBEST3096_31980	COG0628	permease
BsBEST3096_31990	COG0673	inositol 2-dehydrogenase activity
BsBEST3096_32000	COG4806	L-rhamnose isomerase
BsBEST3096_32010	COG3254	rhamnose metabolic process
BsBEST3096_32020	COG1070	Carbohydrate kinase
BsBEST3096_32030	COG1349	DNA-binding transcription factor activity
BsBEST3096_32040	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_32040	COG3347	Dehydrogenase
BsBEST3096_32050	COG0840	transmembrane signaling receptor activity
BsBEST3096_32060	COG0840	transmembrane signaling receptor activity
BsBEST3096_32080	COG0840	transmembrane signaling receptor activity
BsBEST3096_32090	COG0840	transmembrane signaling receptor activity
BsBEST3096_32120	COG0432	Pfam Uncharacterised protein family UPF0047
BsBEST3096_32140	COG0366	Alpha amylase catalytic
BsBEST3096_32150	COG1253	flavin adenine dinucleotide binding
BsBEST3096_32160	COG2738	Putative neutral zinc metallopeptidase
BsBEST3096_32190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BsBEST3096_32220	COG0166	Belongs to the GPI family
BsBEST3096_32230	COG1979	alcohol dehydrogenase
BsBEST3096_32240	COG1979	alcohol dehydrogenase
BsBEST3096_32250	COG2155	Conserved Protein
BsBEST3096_32260	COG1098	S1 RNA binding domain
BsBEST3096_32270	COG0436	Aminotransferase
BsBEST3096_32280	COG1522	sequence-specific DNA binding
BsBEST3096_32290	COG2267	carboxylic ester hydrolase activity
BsBEST3096_32310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BsBEST3096_32320	COG2205	protein histidine kinase activity
BsBEST3096_32340	COG5018	Exonuclease
BsBEST3096_32360	COG2814	Major facilitator Superfamily
BsBEST3096_32370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3096_32380	COG3011	Protein conserved in bacteria
BsBEST3096_32400	COG3290	protein histidine kinase activity
BsBEST3096_32410	COG4565	transcriptional regulatory protein
BsBEST3096_32420	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3096_32430	COG3845	ABC transporter
BsBEST3096_32440	COG4603	Belongs to the binding-protein-dependent transport system permease family
BsBEST3096_32450	COG1079	Belongs to the binding-protein-dependent transport system permease family
BsBEST3096_32460	COG3493	citrate carrier protein
BsBEST3096_32480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3096_32480	COG2111	Na H antiporter
BsBEST3096_32490	COG2111	Na H antiporter
BsBEST3096_32500	COG1006	Multisubunit Na H antiporter MnhC subunit
BsBEST3096_32510	COG0651	ATP synthesis coupled electron transport
BsBEST3096_32520	COG1863	multisubunit Na H antiporter MnhE subunit
BsBEST3096_32530	COG2212	antiporter activity
BsBEST3096_32540	COG1320	monovalent cation:proton antiporter activity
BsBEST3096_32550	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3096_32560	COG2197	response regulator
BsBEST3096_32570	COG4585	Histidine kinase
BsBEST3096_32600	COG0142	geranyltranstransferase activity
BsBEST3096_32630	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BsBEST3096_32640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BsBEST3096_32650	COG1335	isochorismatase
BsBEST3096_32660	COG5506	Protein of unknown function (DUF1694)
BsBEST3096_32690	COG0628	permease
BsBEST3096_32720	COG1418	mRNA catabolic process
BsBEST3096_32730	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_32750	COG1511	domain protein
BsBEST3096_32760	COG0433	COG0433 Predicted ATPase
BsBEST3096_32760	COG1674	ftsk spoiiie
BsBEST3096_32770	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3096_32780	COG5417	Belongs to the EsaB family
BsBEST3096_32790	COG4842	Belongs to the WXG100 family
BsBEST3096_32800	COG2508	Transcriptional regulator
BsBEST3096_32800	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3096_32810	COG0686	Belongs to the AlaDH PNT family
BsBEST3096_32820	COG5634	Uncharacterized conserved protein (DUF2278)
BsBEST3096_32830	COG3251	PFAM MbtH domain protein
BsBEST3096_32840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_32850	COG1535	isochorismatase
BsBEST3096_32850	COG3433	isochorismatase activity
BsBEST3096_32860	COG1021	2,3-dihydroxybenzoate-AMP ligase
BsBEST3096_32870	COG1169	isochorismate synthase
BsBEST3096_32880	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_32890	COG2819	hydrolase of the alpha beta superfamily
BsBEST3096_32900	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3096_32910	COG1268	BioY protein
BsBEST3096_32920	COG2056	Na+-H+ antiporter family
BsBEST3096_32930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BsBEST3096_32940	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BsBEST3096_32950	COG3584	3D domain protein
BsBEST3096_32970	COG1252	NADH dehydrogenase
BsBEST3096_32980	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3096_33000	COG0516	GMP reductase activity
BsBEST3096_33010	COG2808	Putative FMN-binding domain
BsBEST3096_33020	COG0456	acetyltransferase
BsBEST3096_33030	COG0316	Belongs to the HesB IscA family
BsBEST3096_33040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BsBEST3096_33050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3096_33060	COG4844	belongs to the
BsBEST3096_33070	COG1252	NADH dehydrogenase
BsBEST3096_33080	COG4837	Protein of unknown function (DUF1462)
BsBEST3096_33090	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BsBEST3096_33100	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3096_33100	COG1506	peptidase
BsBEST3096_33100	COG4946	Tricorn protease homolog
BsBEST3096_33110	COG0083	homoserine kinase activity
BsBEST3096_33120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BsBEST3096_33130	COG0460	homoserine dehydrogenase
BsBEST3096_33140	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3096_33150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3096_33160	COG0647	UMP catabolic process
BsBEST3096_33170	COG2445	Protein of unknown function DUF86
BsBEST3096_33180	COG4470	Protein conserved in bacteria
BsBEST3096_33200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BsBEST3096_33210	COG0739	heme binding
BsBEST3096_33230	COG3377	Domain of unknown function (DUF1805)
BsBEST3096_33240	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3096_33250	COG0730	response to heat
BsBEST3096_33260	COG1801	Protein of unknown function DUF72
BsBEST3096_33280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3096_33290	COG2508	Transcriptional regulator
BsBEST3096_33300	COG2233	PERMEase
BsBEST3096_33310	COG2233	PERMEase
BsBEST3096_33320	COG3648	Uricase
BsBEST3096_33320	COG3195	allantoin biosynthetic process
BsBEST3096_33330	COG2351	hydroxyisourate hydrolase activity
BsBEST3096_33350	COG2080	2 iron, 2 sulfur cluster binding
BsBEST3096_33360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BsBEST3096_33370	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BsBEST3096_33380	COG2068	MobA-Related Protein
BsBEST3096_33390	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BsBEST3096_33400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BsBEST3096_33410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3096_33420	COG2356	endonuclease I
BsBEST3096_33430	COG3842	ATPase activity
BsBEST3096_33440	COG2188	Transcriptional regulator
BsBEST3096_33450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3096_33460	COG0395	ABC-type sugar transport system, permease component
BsBEST3096_33470	COG1175	transmembrane transport
BsBEST3096_33480	COG1653	transport
BsBEST3096_33490	COG2222	sugar isomerase
BsBEST3096_33500	COG0322	excinuclease ABC activity
BsBEST3096_33510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3096_33540	COG0346	lactoylglutathione lyase activity
BsBEST3096_33550	COG0640	Transcriptional regulator
BsBEST3096_33560	COG0719	Fe-S assembly protein
BsBEST3096_33570	COG0822	iron-sulfur transferase activity
BsBEST3096_33580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3096_33590	COG0719	Fe-S assembly protein
BsBEST3096_33600	COG0396	ATPase activity
BsBEST3096_33620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3096_33630	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3096_33640	COG2011	ABC-type metal ion transport system permease component
BsBEST3096_33650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BsBEST3096_33670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3096_33680	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3096_33700	COG0509	glycine decarboxylation via glycine cleavage system
BsBEST3096_33710	COG1393	Belongs to the ArsC family
BsBEST3096_33720	COG1960	acyl-CoA dehydrogenase activity
BsBEST3096_33730	COG0183	Belongs to the thiolase family
BsBEST3096_33740	COG1024	Enoyl-CoA hydratase
BsBEST3096_33740	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3096_33760	COG0506	proline dehydrogenase activity
BsBEST3096_33780	COG5577	PFAM Coat F domain
BsBEST3096_33790	COG1846	Transcriptional regulator
BsBEST3096_33800	COG0477	Major facilitator Superfamily
BsBEST3096_33810	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3096_33820	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_33830	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_33840	COG0583	DNA-binding transcription factor activity
BsBEST3096_33860	COG1120	ATPase activity
BsBEST3096_33900	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_33910	COG0783	Belongs to the Dps family
BsBEST3096_33920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3096_33930	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_33940	COG2205	protein histidine kinase activity
BsBEST3096_33940	COG2770	Histidine kinase
BsBEST3096_33960	COG1309	transcriptional regulator
BsBEST3096_33970	COG0114	fumarate hydratase activity
BsBEST3096_33990	COG0697	spore germination
BsBEST3096_34000	COG0814	amino acid
BsBEST3096_34030	COG2197	response regulator
BsBEST3096_34040	COG4585	Histidine kinase
BsBEST3096_34050	COG4758	membrane
BsBEST3096_34060	COG3595	metallopeptidase activity
BsBEST3096_34070	COG1842	Phage shock protein A
BsBEST3096_34080	COG4758	membrane
BsBEST3096_34090	COG2814	Major facilitator Superfamily
BsBEST3096_34100	COG2096	Adenosyltransferase
BsBEST3096_34110	COG1120	ATPase activity
BsBEST3096_34120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3096_34130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3096_34140	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_34150	COG3386	PFAM SMP-30 Gluconolaconase
BsBEST3096_34160	COG2205	protein histidine kinase activity
BsBEST3096_34170	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_34190	COG1191	sigma factor activity
BsBEST3096_34210	COG2140	Oxalate decarboxylase
BsBEST3096_34230	COG0577	efflux transmembrane transporter activity
BsBEST3096_34240	COG1136	(ABC) transporter
BsBEST3096_34250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3096_34260	COG1120	ATPase activity
BsBEST3096_34270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3096_34280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3096_34290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3096_34300	COG0531	amino acid
BsBEST3096_34320	COG1988	membrane-bound metal-dependent
BsBEST3096_34330	COG1368	sulfuric ester hydrolase activity
BsBEST3096_34340	COG1910	domain protein
BsBEST3096_34350	COG0725	ABC transporter, periplasmic molybdate-binding protein
BsBEST3096_34360	COG4149	molybdate abc transporter
BsBEST3096_34370	COG0656	L-ascorbic acid biosynthetic process
BsBEST3096_34390	COG0025	NhaP-type Na H and K H
BsBEST3096_34400	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3096_34410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3096_34420	COG3973	AAA domain
BsBEST3096_34430	COG2860	membrane
BsBEST3096_34440	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3096_34450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BsBEST3096_34460	COG2217	Heavy metal translocating P-type atpase
BsBEST3096_34470	COG2217	Heavy metal translocating P-type atpase
BsBEST3096_34480	COG2608	mercury ion transmembrane transporter activity
BsBEST3096_34490	COG1937	Protein conserved in bacteria
BsBEST3096_34500	COG0673	inositol 2-dehydrogenase activity
BsBEST3096_34510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3096_34520	COG1289	transmembrane transporter activity
BsBEST3096_34540	COG2076	Multidrug Resistance protein
BsBEST3096_34550	COG1309	transcriptional regulator
BsBEST3096_34560	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_34570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BsBEST3096_34580	COG0557	exoribonuclease II activity
BsBEST3096_34590	COG1647	Serine aminopeptidase, S33
BsBEST3096_34600	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3096_34610	COG0596	Alpha beta hydrolase
BsBEST3096_34620	COG1476	TRANSCRIPTIONal
BsBEST3096_34630	COG1396	sequence-specific DNA binding
BsBEST3096_34640	COG1396	sequence-specific DNA binding
BsBEST3096_34650	COG1733	regulation of RNA biosynthetic process
BsBEST3096_34660	COG0840	transmembrane signaling receptor activity
BsBEST3096_34670	COG1174	glycine betaine transport
BsBEST3096_34680	COG1732	Glycine betaine
BsBEST3096_34690	COG1174	glycine betaine transport
BsBEST3096_34700	COG0517	IMP dehydrogenase activity
BsBEST3096_34700	COG1125	glycine betaine transport
BsBEST3096_34710	COG1510	regulation of RNA biosynthetic process
BsBEST3096_34750	COG5658	integral membrane protein
BsBEST3096_34760	COG0640	Transcriptional regulator
BsBEST3096_34770	COG1174	glycine betaine transport
BsBEST3096_34780	COG1732	Glycine betaine
BsBEST3096_34790	COG1174	glycine betaine transport
BsBEST3096_34800	COG0517	IMP dehydrogenase activity
BsBEST3096_34800	COG1125	glycine betaine transport
BsBEST3096_34810	COG1510	regulation of RNA biosynthetic process
BsBEST3096_34820	COG2095	MarC family integral membrane protein
BsBEST3096_34840	COG3064	Membrane
BsBEST3096_34850	COG4640	response to antibiotic
BsBEST3096_34860	COG0456	acetyltransferase
BsBEST3096_34870	COG0148	phosphopyruvate hydratase activity
BsBEST3096_34880	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BsBEST3096_34890	COG0149	triose-phosphate isomerase activity
BsBEST3096_34900	COG0126	phosphoglycerate kinase activity
BsBEST3096_34910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3096_34920	COG2390	Transcriptional regulator
BsBEST3096_34930	COG2814	Major facilitator Superfamily
BsBEST3096_34940	COG1609	Transcriptional regulator
BsBEST3096_34950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3096_34960	COG0583	DNA-binding transcription factor activity
BsBEST3096_34970	COG0697	spore germination
BsBEST3096_34980	COG1113	amino acid transport
BsBEST3096_34990	COG3858	chitin binding
BsBEST3096_35000	COG1556	Lactate utilization protein
BsBEST3096_35010	COG1139	Iron-sulfur cluster binding protein
BsBEST3096_35020	COG0247	lactate metabolic process
BsBEST3096_35030	COG2197	response regulator
BsBEST3096_35040	COG4585	Histidine kinase
BsBEST3096_35050	COG0842	Transport permease protein
BsBEST3096_35060	COG1131	(ABC) transporter
BsBEST3096_35070	COG0596	Alpha beta hydrolase
BsBEST3096_35080	COG2208	phosphoserine phosphatase activity
BsBEST3096_35090	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BsBEST3096_35100	COG1874	Beta-galactosidase
BsBEST3096_35110	COG3833	ABC-type maltose transport systems, permease component
BsBEST3096_35120	COG1175	transmembrane transport
BsBEST3096_35130	COG2182	Extracellular solute-binding protein
BsBEST3096_35140	COG1609	Transcriptional regulator
BsBEST3096_35150	COG2186	Transcriptional regulator
BsBEST3096_35160	COG1620	l-lactate permease
BsBEST3096_35170	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BsBEST3096_35190	COG5039	Polysaccharide pyruvyl transferase
BsBEST3096_35200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3096_35210	COG0110	maltose O-acetyltransferase activity
BsBEST3096_35220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BsBEST3096_35230	COG2244	polysaccharide biosynthetic process
BsBEST3096_35240	COG1216	Glycosyl transferase, family 2
BsBEST3096_35250	COG5039	Polysaccharide pyruvyl transferase
BsBEST3096_35260	COG1216	Glycosyl transferase, family 2
BsBEST3096_35280	COG0438	transferase activity, transferring glycosyl groups
BsBEST3096_35290	COG1215	transferase activity, transferring glycosyl groups
BsBEST3096_35300	COG0438	transferase activity, transferring glycosyl groups
BsBEST3096_35310	COG1086	Polysaccharide biosynthesis protein
BsBEST3096_35320	COG0489	protein tyrosine kinase activity
BsBEST3096_35330	COG3944	biosynthesis protein
BsBEST3096_35340	COG1396	sequence-specific DNA binding
BsBEST3096_35350	COG2272	Belongs to the type-B carboxylesterase lipase family
BsBEST3096_35370	COG3479	Phenolic acid decarboxylase
BsBEST3096_35390	COG1794	racemase activity, acting on amino acids and derivatives
BsBEST3096_35400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3096_35410	COG1621	beta-fructofuranosidase activity
BsBEST3096_35420	COG1621	beta-fructofuranosidase activity
BsBEST3096_35430	COG0531	amino acid
BsBEST3096_35440	COG1309	transcriptional regulator
BsBEST3096_35450	COG2076	Multidrug Resistance protein
BsBEST3096_35460	COG2076	Multidrug Resistance protein
BsBEST3096_35480	COG0277	FAD linked oxidase domain protein
BsBEST3096_35490	COG3621	Patatin-like phospholipase
BsBEST3096_35500	COG0740	serine-type endopeptidase activity
BsBEST3096_35510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3096_35520	COG0366	Alpha amylase catalytic
BsBEST3096_35530	COG1554	hydrolase, family 65, central catalytic
BsBEST3096_35540	COG5521	maltodextrose utilization protein MalA
BsBEST3096_35550	COG3833	ABC-type maltose transport systems, permease component
BsBEST3096_35560	COG1175	transmembrane transport
BsBEST3096_35570	COG2182	Extracellular solute-binding protein
BsBEST3096_35580	COG0366	Alpha amylase catalytic
BsBEST3096_35590	COG1609	Transcriptional regulator
BsBEST3096_35600	COG1611	Belongs to the LOG family
BsBEST3096_35610	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3096_35630	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3096_35640	COG0288	reversible hydration of carbon dioxide
BsBEST3096_35650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3096_35660	COG0577	efflux transmembrane transporter activity
BsBEST3096_35670	COG1136	(ABC) transporter
BsBEST3096_35680	COG5002	protein histidine kinase activity
BsBEST3096_35690	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_35710	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BsBEST3096_35720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3096_35730	COG1481	regulation of sporulation
BsBEST3096_35740	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BsBEST3096_35750	COG1660	Displays ATPase and GTPase activities
BsBEST3096_35760	COG1051	belongs to the nudix hydrolase family
BsBEST3096_35770	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3096_35780	COG0791	NLP P60 protein
BsBEST3096_35780	COG3883	PFAM NLP P60 protein
BsBEST3096_35790	COG0457	Tetratricopeptide repeat
BsBEST3096_35800	COG1132	(ABC) transporter
BsBEST3096_35840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BsBEST3096_35840	COG0140	phosphoribosyl-ATP diphosphatase activity
BsBEST3096_35850	COG0107	imidazoleglycerol-phosphate synthase activity
BsBEST3096_35860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BsBEST3096_35870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BsBEST3096_35880	COG0131	Imidazoleglycerol-phosphate dehydratase
BsBEST3096_35890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BsBEST3096_35900	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BsBEST3096_35910	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BsBEST3096_35920	COG4990	cell redox homeostasis
BsBEST3096_35930	COG5297	Belongs to the glycosyl hydrolase family 6
BsBEST3096_35940	COG0110	maltose O-acetyltransferase activity
BsBEST3096_35950	COG0546	phosphoglycolate phosphatase activity
BsBEST3096_35960	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BsBEST3096_35970	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BsBEST3096_35980	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BsBEST3096_35990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BsBEST3096_36000	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3096_36010	COG2188	Transcriptional regulator
BsBEST3096_36020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3096_36030	COG1846	Transcriptional regulator
BsBEST3096_36040	COG2124	cytochrome p450
BsBEST3096_36060	COG1846	Transcriptional regulator
BsBEST3096_36070	COG2814	Major facilitator Superfamily
BsBEST3096_36080	COG1950	PFAM Membrane protein of
BsBEST3096_36090	COG1983	PspC domain protein
BsBEST3096_36100	COG3595	metallopeptidase activity
BsBEST3096_36130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3096_36140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BsBEST3096_36150	COG0556	nucleotide-excision repair
BsBEST3096_36160	COG4897	Protein conserved in bacteria
BsBEST3096_36170	COG3848	Pyruvate phosphate dikinase
BsBEST3096_36170	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3096_36180	COG1309	transcriptional regulator
BsBEST3096_36190	COG2814	Major facilitator Superfamily
BsBEST3096_36200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3096_36220	COG0793	Belongs to the peptidase S41A family
BsBEST3096_36220	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3096_36230	COG2177	Part of the ABC transporter FtsEX involved in
BsBEST3096_36240	COG2884	Cell division ATP-binding protein ftsE
BsBEST3096_36250	COG2010	Cytochrome c
BsBEST3096_36260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3096_36270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BsBEST3096_36280	COG0653	protein targeting
BsBEST3096_36290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BsBEST3096_36310	COG1516	flagellar protein fliS
BsBEST3096_36320	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BsBEST3096_36330	COG1334	flagellar protein FlaG
BsBEST3096_36340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3096_36350	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BsBEST3096_36360	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BsBEST3096_36380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3096_36390	COG1256	bacterial-type flagellum assembly
BsBEST3096_36390	COG4786	Flagellar basal body rod
BsBEST3096_36400	COG3418	PFAM FlgN family protein
BsBEST3096_36410	COG2747	anti-sigma28 factor FlgM
BsBEST3096_36430	COG1040	competence protein
BsBEST3096_36450	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BsBEST3096_36460	COG1307	EDD domain protein, DegV family
BsBEST3096_36470	COG2197	response regulator
BsBEST3096_36480	COG4585	Histidine kinase
BsBEST3096_36490	COG1739	Uncharacterized protein family UPF0029
BsBEST3096_36500	COG1316	TRANSCRIPTIONal
BsBEST3096_36510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3096_36520	COG0438	transferase activity, transferring glycosyl groups
BsBEST3096_36530	COG1215	transferase activity, transferring glycosyl groups
BsBEST3096_36540	COG3206	protein involved in exopolysaccharide biosynthesis
BsBEST3096_36550	COG3307	-O-antigen
BsBEST3096_36560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3096_36570	COG0297	glycogen (starch) synthase activity
BsBEST3096_36570	COG0438	transferase activity, transferring glycosyl groups
BsBEST3096_36580	COG2244	polysaccharide biosynthetic process
BsBEST3096_36610	COG2247	cell wall binding repeat
BsBEST3096_36610	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3096_36620	COG2247	cell wall binding repeat
BsBEST3096_36620	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3096_36640	COG1316	TRANSCRIPTIONal
BsBEST3096_36650	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BsBEST3096_36660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3096_36670	COG1215	transferase activity, transferring glycosyl groups
BsBEST3096_36670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3096_36680	COG0463	Glycosyl transferase, family 2
BsBEST3096_36700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3096_36710	COG1134	teichoic acid transport
BsBEST3096_36720	COG1682	transport, permease protein
BsBEST3096_36730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3096_36740	COG0438	transferase activity, transferring glycosyl groups
BsBEST3096_36750	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BsBEST3096_36760	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BsBEST3096_36770	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3096_36790	COG4193	domain, Protein
BsBEST3096_36800	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3096_36810	COG0697	spore germination
BsBEST3096_36820	COG0814	amino acid
BsBEST3096_36840	COG2814	Major facilitator Superfamily
BsBEST3096_36850	COG1316	TRANSCRIPTIONal
BsBEST3096_36860	COG0561	phosphatase activity
BsBEST3096_36870	COG0791	NLP P60 protein
BsBEST3096_36890	COG2843	Capsule synthesis protein
BsBEST3096_36910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3096_36920	COG1609	Transcriptional regulator
BsBEST3096_36930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3096_36940	COG1869	D-ribose catabolic process
BsBEST3096_36950	COG1129	ABC transporter
BsBEST3096_36960	COG1172	Belongs to the binding-protein-dependent transport system permease family
BsBEST3096_36970	COG1879	ABC-type sugar transport system periplasmic component
BsBEST3096_36980	COG3103	Sh3 type 3 domain protein
BsBEST3096_37000	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3096_37010	COG3527	Alpha-acetolactate decarboxylase
BsBEST3096_37020	COG0028	Belongs to the TPP enzyme family
BsBEST3096_37030	COG0583	DNA-binding transcription factor activity
BsBEST3096_37040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3096_37070	COG5337	Spore coat protein CotH
BsBEST3096_37090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3096_37110	COG0405	Gamma-glutamyltransferase
BsBEST3096_37120	COG1522	sequence-specific DNA binding
BsBEST3096_37130	COG2059	Chromate
BsBEST3096_37140	COG2059	Chromate
BsBEST3096_37160	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3096_37170	COG0583	DNA-binding transcription factor activity
BsBEST3096_37180	COG1515	deoxyribonuclease V activity
BsBEST3096_37190	COG2849	repeat protein
BsBEST3096_37200	COG5444	nuclease activity
BsBEST3096_37230	COG3878	Protein conserved in bacteria
BsBEST3096_37240	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3096_37250	COG4464	protein tyrosine phosphatase activity
BsBEST3096_37260	COG0489	protein tyrosine kinase activity
BsBEST3096_37270	COG3944	biosynthesis protein
BsBEST3096_37290	COG4715	Zinc finger, swim domain protein
BsBEST3096_37300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3096_37310	COG0561	phosphatase activity
BsBEST3096_37320	COG1349	DNA-binding transcription factor activity
BsBEST3096_37330	COG0629	single-stranded DNA binding
BsBEST3096_37370	COG3764	Sortase (surface protein transpeptidase)
BsBEST3096_37390	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_37390	COG2972	Histidine kinase
BsBEST3096_37400	COG1970	mechanosensitive ion channel activity
BsBEST3096_37410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3096_37420	COG0457	Tetratricopeptide repeat
BsBEST3096_37430	COG4786	Flagellar basal body rod
BsBEST3096_37440	COG4786	Flagellar basal body rod
BsBEST3096_37450	COG1077	Cell shape determining protein MreB Mrl
BsBEST3096_37460	COG1609	Transcriptional regulator
BsBEST3096_37470	COG1846	Transcriptional regulator
BsBEST3096_37480	COG2814	Major facilitator Superfamily
BsBEST3096_37490	COG3420	alginic acid biosynthetic process
BsBEST3096_37500	COG1953	Uracil, thiamine, allantoin
BsBEST3096_37510	COG0477	Major facilitator Superfamily
BsBEST3096_37520	COG1335	isochorismatase
BsBEST3096_37540	COG0004	ammonium transporteR
BsBEST3096_37550	COG0347	Belongs to the P(II) protein family
BsBEST3096_37560	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3096_37580	COG0739	heme binding
BsBEST3096_37590	COG1247	-acetyltransferase
BsBEST3096_37610	COG2089	acid synthase
BsBEST3096_37630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3096_37640	COG0789	Transcriptional regulator
BsBEST3096_37660	COG2910	NAD(P)H-binding
BsBEST3096_37670	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3096_37680	COG0804	urea catabolic process
BsBEST3096_37690	COG0832	Belongs to the urease beta subunit family
BsBEST3096_37700	COG0831	urea catabolic process
BsBEST3096_37720	COG3237	CsbD-like
BsBEST3096_37730	COG1994	Peptidase M50
BsBEST3096_37740	COG0457	Tetratricopeptide repeat
BsBEST3096_37750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BsBEST3096_37760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BsBEST3096_37780	COG2304	oxidoreductase activity
BsBEST3096_37790	COG2304	oxidoreductase activity
BsBEST3096_37810	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3096_37820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3096_37840	COG4836	Membrane
BsBEST3096_37860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BsBEST3096_37870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BsBEST3096_37880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BsBEST3096_37890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BsBEST3096_37900	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BsBEST3096_37910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BsBEST3096_37930	COG0356	it plays a direct role in the translocation of protons across the membrane
BsBEST3096_37950	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BsBEST3096_37960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BsBEST3096_37970	COG4475	Protein of unknown function (DUF436)
BsBEST3096_37980	COG0698	ribose 5-phosphate isomerase
BsBEST3096_37990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3096_38000	COG1971	Probably functions as a manganese efflux pump
BsBEST3096_38010	COG0009	L-threonylcarbamoyladenylate synthase
BsBEST3096_38020	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BsBEST3096_38060	COG2890	protein-(glutamine-N5) methyltransferase activity
BsBEST3096_38070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BsBEST3096_38080	COG0346	lactoylglutathione lyase activity
BsBEST3096_38090	COG0789	Transcriptional regulator
BsBEST3096_38100	COG0679	Auxin Efflux Carrier
BsBEST3096_38110	COG0281	malic enzyme
BsBEST3096_38130	COG1435	thymidine kinase activity
BsBEST3096_38150	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BsBEST3096_38160	COG1494	fructose-1,6-bisphosphatase
BsBEST3096_38170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3096_38180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BsBEST3096_38190	COG0191	fructose-bisphosphate aldolase activity
BsBEST3096_38200	COG2204	response regulator
BsBEST3096_38210	COG4821	SIS domain
BsBEST3096_38220	COG0504	CTP synthase activity
BsBEST3096_38230	COG3343	RNA polymerase activity
BsBEST3096_38240	COG1960	acyl-CoA dehydrogenase activity
BsBEST3096_38250	COG0247	lactate metabolic process
BsBEST3096_38250	COG2181	nitrate reductase activity
BsBEST3096_38260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3096_38270	COG4294	response to UV
BsBEST3096_38290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3096_38300	COG1132	(ABC) transporter
BsBEST3096_38310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3096_38320	COG2181	nitrate reductase activity
BsBEST3096_38330	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BsBEST3096_38340	COG1140	nitrate reductase beta subunit
BsBEST3096_38350	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BsBEST3096_38360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3096_38380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3096_38390	COG2223	nitrite transmembrane transporter activity
BsBEST3096_38400	COG0018	arginyl-trna synthetase
BsBEST3096_38410	COG4506	Protein conserved in bacteria
BsBEST3096_38430	COG0535	radical SAM domain protein
BsBEST3096_38450	COG1131	(ABC) transporter
BsBEST3096_38460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3096_38470	COG0612	Peptidase, M16
BsBEST3096_38480	COG0612	Peptidase, M16
BsBEST3096_38500	COG3391	amine dehydrogenase activity
BsBEST3096_38510	COG3391	amine dehydrogenase activity
BsBEST3096_38520	COG0457	Tetratricopeptide repeat
BsBEST3096_38540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3096_38550	COG0010	Belongs to the arginase family
BsBEST3096_38560	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BsBEST3096_38570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3096_38590	COG1994	Peptidase M50
BsBEST3096_38600	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3096_38610	COG1846	Transcriptional regulator
BsBEST3096_38620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3096_38630	COG0477	Major facilitator Superfamily
BsBEST3096_38640	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3096_38650	COG3465	dGTPase activity
BsBEST3096_38660	COG1078	dGTPase activity
BsBEST3096_38670	COG4844	belongs to the
BsBEST3096_38690	COG0697	spore germination
BsBEST3096_38700	COG0095	Lipoate-protein ligase
BsBEST3096_38710	COG0583	DNA-binding transcription factor activity
BsBEST3096_38720	COG0280	phosphate acetyltransferase
BsBEST3096_38730	COG3253	May function as heme-dependent peroxidase
BsBEST3096_38740	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_38750	COG0436	Aminotransferase
BsBEST3096_38760	COG2814	Major facilitator Superfamily
BsBEST3096_38770	COG0151	Belongs to the GarS family
BsBEST3096_38780	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_38790	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3096_38800	COG0077	Prephenate dehydratase
BsBEST3096_38810	COG2814	Major facilitator Superfamily
BsBEST3096_38820	COG0833	amino acid
BsBEST3096_38830	COG4187	Peptidase family M20/M25/M40
BsBEST3096_38840	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_38850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3096_38870	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3096_38880	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3096_38890	COG1091	dTDP-4-dehydrorhamnose reductase activity
BsBEST3096_38900	COG1088	dTDP-glucose 4,6-dehydratase activity
BsBEST3096_38910	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BsBEST3096_38920	COG3980	spore coat polysaccharide biosynthesis protein
BsBEST3096_38930	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BsBEST3096_38940	COG2089	acid synthase
BsBEST3096_38950	COG0456	acetyltransferase
BsBEST3096_38960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3096_38970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3096_38980	COG0463	Glycosyl transferase, family 2
BsBEST3096_39000	COG2363	Small membrane protein
BsBEST3096_39010	COG2233	PERMEase
BsBEST3096_39030	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_39040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BsBEST3096_39050	COG1216	Glycosyl transferase, family 2
BsBEST3096_39080	COG1695	Transcriptional regulator
BsBEST3096_39090	COG0351	phosphomethylpyrimidine kinase
BsBEST3096_39110	COG1621	beta-fructofuranosidase activity
BsBEST3096_39120	COG1263	PTS System
BsBEST3096_39120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3096_39130	COG2116	formate transmembrane transporter activity
BsBEST3096_39140	COG3711	transcriptional antiterminator
BsBEST3096_39160	COG1404	Belongs to the peptidase S8 family
BsBEST3096_39170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3096_39180	COG0778	Nitroreductase
BsBEST3096_39190	COG0772	Belongs to the SEDS family
BsBEST3096_39210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3096_39220	COG1845	cytochrome c oxidase, subunit III
BsBEST3096_39230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3096_39240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3096_39250	COG2261	transglycosylase associated protein
BsBEST3096_39260	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BsBEST3096_39270	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BsBEST3096_39280	COG2246	polysaccharide biosynthetic process
BsBEST3096_39290	COG1309	transcriptional regulator
BsBEST3096_39310	COG3162	membrane
BsBEST3096_39320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3096_39330	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3096_39340	COG2837	iron assimilation
BsBEST3096_39350	COG2822	iron ion transport
BsBEST3096_39360	COG0672	)-iron permease
BsBEST3096_39370	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3096_39380	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BsBEST3096_39390	COG0583	DNA-binding transcription factor activity
BsBEST3096_39400	COG1380	Effector of murein hydrolase LrgA
BsBEST3096_39410	COG1346	cytolysis
BsBEST3096_39420	COG2814	Major facilitator Superfamily
BsBEST3096_39430	COG4895	conserved protein (DUF2196)
BsBEST3096_39440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BsBEST3096_39450	COG0346	lactoylglutathione lyase activity
BsBEST3096_39470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3096_39480	COG1404	Belongs to the peptidase S8 family
BsBEST3096_39490	COG1263	PTS System
BsBEST3096_39490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3096_39500	COG3711	transcriptional antiterminator
BsBEST3096_39510	COG1442	glycosyl transferase family 8
BsBEST3096_39520	COG5522	Integral membrane protein (intg_mem_TP0381)
BsBEST3096_39530	COG1846	Transcriptional regulator
BsBEST3096_39540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3096_39550	COG2234	aminopeptidase activity
BsBEST3096_39560	COG2357	RelA SpoT domain protein
BsBEST3096_39570	COG1575	Belongs to the MenA family. Type 1 subfamily
BsBEST3096_39580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3096_39590	COG1696	Membrane protein involved in D-alanine export
BsBEST3096_39600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3096_39610	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BsBEST3096_39620	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3096_39630	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3096_39640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3096_39650	COG1486	melibiose metabolic process
BsBEST3096_39660	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3096_39670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3096_39680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3096_39690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3096_39690	COG3711	transcriptional antiterminator
BsBEST3096_39710	COG2094	Belongs to the DNA glycosylase MPG family
BsBEST3096_39720	COG0753	catalase activity
BsBEST3096_39730	COG2814	Major facilitator Superfamily
BsBEST3096_39740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3096_39750	COG1131	(ABC) transporter
BsBEST3096_39790	COG1595	DNA-templated transcription, initiation
BsBEST3096_39800	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3096_39810	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BsBEST3096_39820	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BsBEST3096_39830	COG4988	ABC transporter
BsBEST3096_39840	COG1294	oxidase, subunit
BsBEST3096_39850	COG1271	oxidase subunit
BsBEST3096_39860	COG3493	citrate carrier protein
BsBEST3096_39870	COG0501	Belongs to the peptidase M48B family
BsBEST3096_39890	COG0726	polysaccharide deacetylase
BsBEST3096_39900	COG3842	ATPase activity
BsBEST3096_39910	COG2508	Transcriptional regulator
BsBEST3096_39920	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_39930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3096_39950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BsBEST3096_39960	COG1881	PFAM PEBP family protein
BsBEST3096_39970	COG0583	DNA-binding transcription factor activity
BsBEST3096_39990	COG4585	Histidine kinase
BsBEST3096_40000	COG2197	response regulator
BsBEST3096_40010	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3096_40030	COG4894	glucomannan catabolic process
BsBEST3096_40040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3096_40050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3096_40060	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_40070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3096_40080	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3096_40090	COG2610	gluconate transmembrane transporter activity
BsBEST3096_40100	COG0500	methyltransferase
BsBEST3096_40110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3096_40140	COG0693	protein deglycase activity
BsBEST3096_40140	COG0753	catalase activity
BsBEST3096_40150	COG2851	Citrate transporter
BsBEST3096_40160	COG2273	Hydrolase Family 16
BsBEST3096_40170	COG3711	transcriptional antiterminator
BsBEST3096_40190	COG2270	Major facilitator Superfamily
BsBEST3096_40200	COG0513	Belongs to the DEAD box helicase family
BsBEST3096_40210	COG2755	lipolytic protein G-D-S-L family
BsBEST3096_40210	COG3401	FG-GAP repeat protein
BsBEST3096_40450	COG0697	spore germination
BsBEST3096_40480	COG0589	response to stress
BsBEST3096_40490	COG2723	6-phospho-beta-galactosidase activity
BsBEST3096_40500	COG2723	6-phospho-beta-galactosidase activity
BsBEST3096_40510	COG1263	PTS System
BsBEST3096_40510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3096_40510	COG2190	(PTS) system
BsBEST3096_40540	COG5444	nuclease activity
BsBEST3096_40570	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3096_40600	COG2986	histidine ammonia-lyase
BsBEST3096_40610	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BsBEST3096_40620	COG1228	amidohydrolase
BsBEST3096_40630	COG0010	Belongs to the arginase family
BsBEST3096_40640	COG0833	amino acid
BsBEST3096_40650	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BsBEST3096_40660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3096_40670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BsBEST3096_40680	COG2390	Transcriptional regulator
BsBEST3096_40700	COG3192	ethanolamine utilization protein
BsBEST3096_40710	COG2079	MmgE PrpD family protein
BsBEST3096_40720	COG1473	amidohydrolase
BsBEST3096_40730	COG1126	abc transporter atp-binding protein
BsBEST3096_40740	COG0765	amino acid transport
BsBEST3096_40750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3096_40760	COG0456	acetyltransferase
BsBEST3096_40770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3096_40790	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BsBEST3096_40800	COG0561	phosphatase activity
BsBEST3096_40860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3096_40870	COG5294	Protein conserved in bacteria
BsBEST3096_40880	COG0577	efflux transmembrane transporter activity
BsBEST3096_40890	COG0577	efflux transmembrane transporter activity
BsBEST3096_40900	COG1136	(ABC) transporter
BsBEST3096_40910	COG1136	(ABC) transporter
BsBEST3096_40920	COG2205	protein histidine kinase activity
BsBEST3096_40930	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_40940	COG0191	fructose-bisphosphate aldolase activity
BsBEST3096_40950	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3096_40960	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3096_40970	COG0673	inositol 2-dehydrogenase activity
BsBEST3096_40980	COG2814	Major facilitator Superfamily
BsBEST3096_40990	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3096_41000	COG3962	Belongs to the TPP enzyme family
BsBEST3096_41010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3096_41020	COG3718	enzyme involved in inositol metabolism
BsBEST3096_41030	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_41040	COG1349	DNA-binding transcription factor activity
BsBEST3096_41050	COG0667	Aldo Keto reductase
BsBEST3096_41080	COG2814	Major facilitator Superfamily
BsBEST3096_41090	COG0326	Molecular chaperone. Has ATPase activity
BsBEST3096_41110	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_41120	COG1309	transcriptional regulator
BsBEST3096_41130	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3096_41140	COG0456	acetyltransferase
BsBEST3096_41150	COG2850	peptidyl-arginine hydroxylation
BsBEST3096_41160	COG2226	methyltransferase
BsBEST3096_41190	COG0367	asparagine synthase
BsBEST3096_41200	COG2814	Major facilitator Superfamily
BsBEST3096_41210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BsBEST3096_41230	COG1714	RDD family
BsBEST3096_41240	COG2311	Membrane
BsBEST3096_41250	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3096_41260	COG1309	transcriptional regulator
BsBEST3096_41270	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3096_41280	COG1846	Transcriptional regulator
BsBEST3096_41290	COG1380	Effector of murein hydrolase LrgA
BsBEST3096_41300	COG1346	cytolysis
BsBEST3096_41310	COG5039	Polysaccharide pyruvyl transferase
BsBEST3096_41320	COG1929	Belongs to the glycerate kinase type-1 family
BsBEST3096_41330	COG1802	Transcriptional regulator
BsBEST3096_41340	COG1070	Carbohydrate kinase
BsBEST3096_41350	COG2610	gluconate transmembrane transporter activity
BsBEST3096_41360	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3096_41370	COG0450	alkyl hydroperoxide reductase
BsBEST3096_41380	COG3634	alkyl hydroperoxide reductase activity
BsBEST3096_41390	COG2723	6-phospho-beta-galactosidase activity
BsBEST3096_41400	COG2190	(PTS) system
BsBEST3096_41410	COG2188	Transcriptional regulator
BsBEST3096_41440	COG1131	(ABC) transporter
BsBEST3096_41450	COG1994	Peptidase M50
BsBEST3096_41460	COG0535	radical SAM domain protein
BsBEST3096_41480	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BsBEST3096_41490	COG5293	efflux transmembrane transporter activity
BsBEST3096_41510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3096_41520	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BsBEST3096_41550	COG1063	alcohol dehydrogenase
BsBEST3096_41590	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BsBEST3096_41600	COG0456	acetyltransferase
BsBEST3096_41610	COG0457	Tetratricopeptide repeat
BsBEST3096_41620	COG0010	Belongs to the arginase family
BsBEST3096_41630	COG0833	amino acid
BsBEST3096_41640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3096_41650	COG3829	transcription factor binding
BsBEST3096_41660	COG5002	protein histidine kinase activity
BsBEST3096_41680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3096_41690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BsBEST3096_41700	COG4853	Protein conserved in bacteria
BsBEST3096_41710	COG4863	YycH protein
BsBEST3096_41720	COG5002	protein histidine kinase activity
BsBEST3096_41730	COG0745	RESPONSE REGULATOR receiver
BsBEST3096_41750	COG0346	lactoylglutathione lyase activity
BsBEST3096_41760	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3096_41790	COG3093	addiction module antidote protein HigA
BsBEST3096_41800	COG2807	transmembrane transport
BsBEST3096_41810	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3096_41820	COG0359	binds to the 23S rRNA
BsBEST3096_41830	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BsBEST3096_41840	COG4241	membrane
BsBEST3096_41860	COG5577	PFAM Coat F domain
BsBEST3096_41870	COG1733	regulation of RNA biosynthetic process
BsBEST3096_41880	COG1227	inorganic diphosphatase activity
BsBEST3096_41910	COG2271	Major facilitator Superfamily
BsBEST3096_41980	COG1131	(ABC) transporter
BsBEST3096_42000	COG4319	ketosteroid isomerase
BsBEST3096_42010	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3096_42020	COG2814	Major facilitator Superfamily
BsBEST3096_42030	COG0583	DNA-binding transcription factor activity
BsBEST3096_42040	COG2153	protein acetylation
BsBEST3096_42060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3096_42070	COG1846	Transcriptional regulator
BsBEST3096_42080	COG2153	protein acetylation
BsBEST3096_42090	COG2364	Membrane
BsBEST3096_42100	COG0456	acetyltransferase
BsBEST3096_42110	COG2315	Protein conserved in bacteria
BsBEST3096_42120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3096_42130	COG2814	Major facilitator Superfamily
BsBEST3096_42140	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3096_42150	COG0789	Transcriptional regulator
BsBEST3096_42160	COG0697	spore germination
BsBEST3096_42170	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3096_42180	COG1266	CAAX protease self-immunity
BsBEST3096_42190	COG0477	Major facilitator Superfamily
BsBEST3096_42190	COG2814	Major facilitator Superfamily
BsBEST3096_42200	COG0110	maltose O-acetyltransferase activity
BsBEST3096_42210	COG0346	lactoylglutathione lyase activity
BsBEST3096_42220	COG1609	Transcriptional regulator
BsBEST3096_42230	COG0708	Exodeoxyribonuclease III
BsBEST3096_42240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BsBEST3096_42250	COG0629	single-stranded DNA binding
BsBEST3096_42260	COG0360	Binds together with S18 to 16S ribosomal RNA
BsBEST3096_42270	COG0012	GTP binding
BsBEST3096_42280	COG0243	molybdopterin cofactor binding
BsBEST3096_42290	COG4481	Protein conserved in bacteria
BsBEST3096_42300	COG3949	Membrane
BsBEST3096_42320	COG1475	DNA binding
BsBEST3096_42330	COG1192	Involved in chromosome partitioning
BsBEST3096_42350	COG1475	DNA binding
BsBEST3096_42360	COG0357	Ribosomal RNA small subunit methyltransferase G
BsBEST3096_42370	COG0445	tRNA wobble uridine modification
BsBEST3096_42380	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BsBEST3096_42390	COG1847	R3H domain protein
BsBEST3096_42400	COG0706	membrane insertase activity
BsBEST3096_42410	COG0594	ribonuclease P activity