locus-tag	class	description
BsBEST3102_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BsBEST3102_00020	COG0592	DNA-directed DNA polymerase activity
BsBEST3102_00030	COG2501	S4 domain
BsBEST3102_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BsBEST3102_00060	COG0187	DNA topoisomerase II activity
BsBEST3102_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3102_00090	COG0516	GMP reductase activity
BsBEST3102_00090	COG0517	IMP dehydrogenase activity
BsBEST3102_00100	COG1686	Belongs to the peptidase S11 family
BsBEST3102_00110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BsBEST3102_00120	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BsBEST3102_00130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BsBEST3102_00140	COG1428	Deoxynucleoside kinase
BsBEST3102_00150	COG1428	Deoxynucleoside kinase
BsBEST3102_00160	COG1388	LysM domain
BsBEST3102_00160	COG3858	chitin binding
BsBEST3102_00170	COG1335	isochorismatase
BsBEST3102_00180	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3102_00190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BsBEST3102_00200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BsBEST3102_00210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BsBEST3102_00250	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BsBEST3102_00260	COG3853	Toxic anion resistance protein (TelA)
BsBEST3102_00270	COG1982	Orn Lys Arg decarboxylase major
BsBEST3102_00280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3102_00290	COG3870	Protein conserved in bacteria
BsBEST3102_00300	COG1728	Protein conserved in bacteria
BsBEST3102_00310	COG0470	DNA polymerase III
BsBEST3102_00320	COG1774	PSP1 C-terminal conserved region
BsBEST3102_00330	COG4467	Involved in initiation control of chromosome replication
BsBEST3102_00340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BsBEST3102_00350	COG2827	Endonuclease containing a URI domain
BsBEST3102_00360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BsBEST3102_00370	COG2002	toxin-antitoxin pair type II binding
BsBEST3102_00380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3102_00380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3102_00390	COG0084	hydrolase, TatD family'
BsBEST3102_00400	COG3584	3D domain protein
BsBEST3102_00400	COG3583	domain protein
BsBEST3102_00410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3102_00420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BsBEST3102_00440	COG4466	Protein conserved in bacteria
BsBEST3102_00460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BsBEST3102_00470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3102_00480	COG0251	oxidation-reduction process
BsBEST3102_00490	COG2088	sporulation resulting in formation of a cellular spore
BsBEST3102_00500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BsBEST3102_00510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BsBEST3102_00520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BsBEST3102_00530	COG0193	aminoacyl-tRNA hydrolase activity
BsBEST3102_00550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BsBEST3102_00560	COG2002	toxin-antitoxin pair type II binding
BsBEST3102_00570	COG2244	polysaccharide biosynthetic process
BsBEST3102_00580	COG3956	TIGRFAM MazG family protein
BsBEST3102_00590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BsBEST3102_00620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BsBEST3102_00630	COG1098	S1 RNA binding domain
BsBEST3102_00640	COG2208	phosphoserine phosphatase activity
BsBEST3102_00650	COG2304	oxidoreductase activity
BsBEST3102_00660	COG0515	serine threonine protein kinase
BsBEST3102_00670	COG0037	tRNA processing
BsBEST3102_00680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BsBEST3102_00690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3102_00700	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BsBEST3102_00710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BsBEST3102_00720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3102_00730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3102_00740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3102_00750	COG0512	Glutamine amidotransferase of anthranilate synthase
BsBEST3102_00760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3102_00770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BsBEST3102_00780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BsBEST3102_00790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BsBEST3102_00800	COG1396	sequence-specific DNA binding
BsBEST3102_00810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3102_00820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BsBEST3102_00830	COG4463	regulation of RNA biosynthetic process
BsBEST3102_00840	COG3880	PFAM UvrB UvrC protein
BsBEST3102_00850	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BsBEST3102_00860	COG0542	response to heat
BsBEST3102_00870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BsBEST3102_00880	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BsBEST3102_00890	COG4956	integral membrane protein (PIN domain superfamily)
BsBEST3102_00900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BsBEST3102_00910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BsBEST3102_00920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BsBEST3102_00930	COG1045	serine acetyltransferase
BsBEST3102_00940	COG0215	cysteine-tRNA ligase activity
BsBEST3102_00950	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BsBEST3102_00960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3102_00970	COG3688	RNA-binding protein containing a PIN domain
BsBEST3102_00980	COG1595	DNA-templated transcription, initiation
BsBEST3102_00990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3102_01000	COG0250	Participates in transcription elongation, termination and antitermination
BsBEST3102_01020	COG0081	regulation of translation
BsBEST3102_01030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BsBEST3102_01050	COG2813	Specifically methylates the guanine in position
BsBEST3102_01060	COG0085	RNA polymerase activity
BsBEST3102_01070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BsBEST3102_01080	COG1358	cellular component organization or biogenesis
BsBEST3102_01090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BsBEST3102_01100	COG0049	tRNA binding
BsBEST3102_01110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BsBEST3102_01120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BsBEST3102_01130	COG0596	Alpha beta hydrolase
BsBEST3102_01150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BsBEST3102_01160	COG0088	Forms part of the polypeptide exit tunnel
BsBEST3102_01180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BsBEST3102_01210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BsBEST3102_01220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BsBEST3102_01240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BsBEST3102_01250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BsBEST3102_01270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BsBEST3102_01290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BsBEST3102_01300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BsBEST3102_01310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BsBEST3102_01340	COG0200	Binds to the 23S rRNA
BsBEST3102_01350	COG0201	protein transport
BsBEST3102_01360	COG0563	adenylate kinase activity
BsBEST3102_01370	COG0024	Methionine aminopeptidase
BsBEST3102_01390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BsBEST3102_01400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BsBEST3102_01410	COG0202	RNA polymerase activity
BsBEST3102_01420	COG0203	ribosomal protein L17
BsBEST3102_01430	COG1122	ATPase activity
BsBEST3102_01440	COG1122	ATPase activity
BsBEST3102_01450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3102_01460	COG0101	tRNA pseudouridine synthase activity
BsBEST3102_01470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BsBEST3102_01480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BsBEST3102_01490	COG2226	methyltransferase
BsBEST3102_01510	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_01520	COG0489	protein tyrosine kinase activity
BsBEST3102_01540	COG2194	sulfuric ester hydrolase activity
BsBEST3102_01550	COG0726	polysaccharide deacetylase
BsBEST3102_01560	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3102_01580	COG0385	Bile acid
BsBEST3102_01590	COG2819	hydrolase of the alpha beta superfamily
BsBEST3102_01600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3102_01610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3102_01620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3102_01630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3102_01630	COG2207	Transcriptional regulator
BsBEST3102_01640	COG3876	Protein conserved in bacteria
BsBEST3102_01650	COG1472	Belongs to the glycosyl hydrolase 3 family
BsBEST3102_01660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3102_01670	COG1263	PTS System
BsBEST3102_01670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3102_01680	COG1737	Transcriptional regulator
BsBEST3102_01690	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BsBEST3102_01700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3102_01710	COG1683	Conserved Protein
BsBEST3102_01720	COG1595	DNA-templated transcription, initiation
BsBEST3102_01730	COG5662	AntiSigma factor
BsBEST3102_01740	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3102_01750	COG4856	YbbR-like protein
BsBEST3102_01760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3102_01770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BsBEST3102_01790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3102_01800	COG2169	Transcriptional regulator
BsBEST3102_01810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3102_01820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3102_01830	COG3002	Belongs to the UPF0753 family
BsBEST3102_01840	COG0288	reversible hydration of carbon dioxide
BsBEST3102_01860	COG5609	conserved protein (DUF2294)
BsBEST3102_01870	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_01880	COG0642	Histidine kinase
BsBEST3102_01900	COG0515	serine threonine protein kinase
BsBEST3102_01930	COG1113	amino acid transport
BsBEST3102_01960	COG2602	Beta-lactamase
BsBEST3102_01970	COG2124	cytochrome p450
BsBEST3102_01990	COG0531	amino acid
BsBEST3102_02000	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3102_02010	COG2271	Major facilitator Superfamily
BsBEST3102_02030	COG0456	acetyltransferase
BsBEST3102_02030	COG1846	Transcriptional regulator
BsBEST3102_02040	COG2271	Major facilitator Superfamily
BsBEST3102_02060	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_02070	COG0697	spore germination
BsBEST3102_02080	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3102_02080	COG2207	Transcriptional regulator
BsBEST3102_02090	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BsBEST3102_02100	COG3591	Belongs to the peptidase S1B family
BsBEST3102_02120	COG0596	Alpha beta hydrolase
BsBEST3102_02130	COG1183	phosphatidylcholine synthase activity
BsBEST3102_02140	COG0586	Pfam SNARE associated Golgi protein
BsBEST3102_02150	COG0688	phosphatidylethanolamine metabolic process
BsBEST3102_02170	COG2312	Erythromycin esterase
BsBEST3102_02180	COG2207	Transcriptional regulator
BsBEST3102_02190	COG1054	Belongs to the UPF0176 family
BsBEST3102_02200	COG1301	dicarboxylic acid transport
BsBEST3102_02210	COG1263	PTS System
BsBEST3102_02210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3102_02210	COG2190	(PTS) system
BsBEST3102_02220	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3102_02230	COG2188	Transcriptional regulator
BsBEST3102_02250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3102_02260	COG0833	amino acid
BsBEST3102_02270	COG2040	homocysteine
BsBEST3102_02280	COG1115	amino acid carrier protein
BsBEST3102_02290	COG1115	amino acid carrier protein
BsBEST3102_02300	COG2066	Belongs to the glutaminase family
BsBEST3102_02310	COG4191	Histidine kinase
BsBEST3102_02320	COG0784	Response regulator, receiver
BsBEST3102_02330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3102_02340	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_02350	COG2271	Major facilitator Superfamily
BsBEST3102_02360	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3102_02370	COG2186	Transcriptional regulator
BsBEST3102_02380	COG2721	sulfolactate sulfo-lyase activity
BsBEST3102_02390	COG3173	Aminoglycoside phosphotransferase
BsBEST3102_02410	COG0697	spore germination
BsBEST3102_02420	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_02430	COG2205	protein histidine kinase activity
BsBEST3102_02440	COG1131	(ABC) transporter
BsBEST3102_02470	COG3773	Cell wall hydrolase
BsBEST3102_02480	COG2304	oxidoreductase activity
BsBEST3102_02490	COG3540	Alkaline phosphatase
BsBEST3102_02500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3102_02510	COG0805	protein transport
BsBEST3102_02520	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BsBEST3102_02530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3102_02540	COG0477	Major facilitator Superfamily
BsBEST3102_02550	COG1309	transcriptional regulator
BsBEST3102_02560	COG0252	asparaginase activity
BsBEST3102_02570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3102_02580	COG1714	RDD family
BsBEST3102_02590	COG1405	negative regulation of cell septum assembly
BsBEST3102_02590	COG3012	SEC-C Motif Domain Protein
BsBEST3102_02600	COG3290	protein histidine kinase activity
BsBEST3102_02610	COG3279	Response regulator of the LytR AlgR family
BsBEST3102_02620	COG4555	ABC transporter
BsBEST3102_02630	COG1668	transmembrane transport
BsBEST3102_02640	COG0667	Aldo Keto reductase
BsBEST3102_02660	COG1595	DNA-templated transcription, initiation
BsBEST3102_02670	COG1595	DNA-templated transcription, initiation
BsBEST3102_02680	COG1876	peptidase activity
BsBEST3102_02690	COG0457	Tetratricopeptide repeat
BsBEST3102_02700	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_02710	COG0366	Alpha amylase catalytic
BsBEST3102_02720	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3102_02730	COG1121	(ABC) transporter
BsBEST3102_02740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3102_02750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3102_02760	COG2310	stress, protein
BsBEST3102_02770	COG2310	stress, protein
BsBEST3102_02780	COG2310	stress, protein
BsBEST3102_02790	COG0861	Integral membrane protein TerC family
BsBEST3102_02810	COG3853	Toxic anion resistance protein (TelA)
BsBEST3102_02820	COG0477	Major facilitator Superfamily
BsBEST3102_02830	COG2814	Major facilitator Superfamily
BsBEST3102_02840	COG0640	Transcriptional regulator
BsBEST3102_02850	COG0517	IMP dehydrogenase activity
BsBEST3102_02850	COG4175	Glycine betaine
BsBEST3102_02860	COG4176	ABC-type proline glycine betaine transport system permease component
BsBEST3102_02870	COG2113	Glycine betaine
BsBEST3102_02880	COG1473	amidohydrolase
BsBEST3102_02890	COG1288	antiporter activity
BsBEST3102_02910	COG0366	Alpha amylase catalytic
BsBEST3102_02920	COG0039	L-malate dehydrogenase activity
BsBEST3102_02930	COG1620	l-lactate permease
BsBEST3102_02940	COG2814	Major facilitator Superfamily
BsBEST3102_02950	COG1846	Transcriptional regulator
BsBEST3102_02960	COG1280	lysine exporter protein (LysE YggA)
BsBEST3102_02970	COG3403	YqcI/YcgG family
BsBEST3102_02980	COG1113	amino acid transport
BsBEST3102_02990	COG3665	Urea carboxylase-associated protein
BsBEST3102_03000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BsBEST3102_03010	COG1660	Displays ATPase and GTPase activities
BsBEST3102_03020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BsBEST3102_03030	COG2226	methyltransferase
BsBEST3102_03040	COG0583	DNA-binding transcription factor activity
BsBEST3102_03050	COG3458	cephalosporin-C deacetylase activity
BsBEST3102_03060	COG3541	Predicted nucleotidyltransferase
BsBEST3102_03070	COG0506	proline dehydrogenase activity
BsBEST3102_03080	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_03090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3102_03100	COG2508	Transcriptional regulator
BsBEST3102_03110	COG3689	TIGRFAM TIGR03943 family protein
BsBEST3102_03120	COG0701	Predicted permease
BsBEST3102_03130	COG2267	carboxylic ester hydrolase activity
BsBEST3102_03140	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3102_03150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3102_03150	COG1587	Uroporphyrinogen-III synthase
BsBEST3102_03160	COG2146	nitrite reductase [NAD(P)H] activity
BsBEST3102_03170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3102_03180	COG0243	molybdopterin cofactor binding
BsBEST3102_03190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3102_03200	COG2223	nitrite transmembrane transporter activity
BsBEST3102_03210	COG1469	GTP cyclohydrolase I activity
BsBEST3102_03220	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3102_03230	COG0523	cobalamin synthesis protein
BsBEST3102_03240	COG0765	amino acid transport
BsBEST3102_03250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3102_03270	COG1714	RDD family
BsBEST3102_03290	COG2723	6-phospho-beta-galactosidase activity
BsBEST3102_03310	COG3209	COG3209 Rhs family protein
BsBEST3102_03320	COG0840	transmembrane signaling receptor activity
BsBEST3102_03320	COG3290	protein histidine kinase activity
BsBEST3102_03330	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BsBEST3102_03340	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BsBEST3102_03350	COG1733	regulation of RNA biosynthetic process
BsBEST3102_03360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_03370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_03380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_03390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_03400	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BsBEST3102_03410	COG2814	Major facilitator Superfamily
BsBEST3102_03430	COG0697	spore germination
BsBEST3102_03440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3102_03470	COG2364	Membrane
BsBEST3102_03480	COG1126	abc transporter atp-binding protein
BsBEST3102_03490	COG0765	amino acid transport
BsBEST3102_03500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3102_03510	COG0583	DNA-binding transcription factor activity
BsBEST3102_03520	COG0163	prenyltransferase activity
BsBEST3102_03530	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BsBEST3102_03560	COG0596	Alpha beta hydrolase
BsBEST3102_03570	COG3104	oligopeptide transport
BsBEST3102_03580	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3102_03600	COG0697	spore germination
BsBEST3102_03620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3102_03630	COG1136	(ABC) transporter
BsBEST3102_03640	COG0577	efflux transmembrane transporter activity
BsBEST3102_03650	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_03660	COG3850	Histidine kinase
BsBEST3102_03660	COG5002	protein histidine kinase activity
BsBEST3102_03670	COG0457	Tetratricopeptide repeat
BsBEST3102_03690	COG0527	aspartate kinase activity
BsBEST3102_03700	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3102_03710	COG4605	iron ion homeostasis
BsBEST3102_03720	COG4604	ABC transporter, ATP-binding protein
BsBEST3102_03730	COG4607	ABC-type enterochelin transport system periplasmic component
BsBEST3102_03740	COG2814	Major facilitator Superfamily
BsBEST3102_03750	COG1309	transcriptional regulator
BsBEST3102_03760	COG0778	Nitroreductase
BsBEST3102_03770	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3102_03780	COG0640	Transcriptional regulator
BsBEST3102_03790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3102_03800	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BsBEST3102_03810	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_03820	COG4975	Glucose uptake
BsBEST3102_03830	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_03840	COG4549	nuclear export factor GLE1
BsBEST3102_03850	COG2372	response to copper ion
BsBEST3102_03850	COG1276	copper resistance
BsBEST3102_03860	COG1349	DNA-binding transcription factor activity
BsBEST3102_03880	COG2213	PTS system mannitol-specific
BsBEST3102_03890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3102_03900	COG0246	Mannitol dehydrogenase
BsBEST3102_03910	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3102_03930	COG0681	Belongs to the peptidase S26 family
BsBEST3102_03940	COG0412	Dienelactone hydrolase
BsBEST3102_03950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3102_03970	COG0561	phosphatase activity
BsBEST3102_03980	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3102_03990	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3102_04000	COG4336	lyase activity
BsBEST3102_04010	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3102_04020	COG1984	allophanate hydrolase subunit 2
BsBEST3102_04030	COG1414	Transcriptional regulator
BsBEST3102_04040	COG2755	lipolytic protein G-D-S-L family
BsBEST3102_04060	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3102_04070	COG0768	penicillin binding
BsBEST3102_04080	COG4989	oxidoreductase activity
BsBEST3102_04090	COG3711	transcriptional antiterminator
BsBEST3102_04100	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3102_04110	COG2226	methyltransferase
BsBEST3102_04120	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_04130	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3102_04140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3102_04150	COG3871	stress protein (general stress protein 26)
BsBEST3102_04170	COG2814	Major facilitator Superfamily
BsBEST3102_04180	COG1522	sequence-specific DNA binding
BsBEST3102_04190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3102_04190	COG0551	DNA topoisomerase type I activity
BsBEST3102_04200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BsBEST3102_04210	COG3706	GGDEF domain
BsBEST3102_04220	COG5298	Protein conserved in bacteria
BsBEST3102_04230	COG1215	transferase activity, transferring glycosyl groups
BsBEST3102_04250	COG0531	amino acid
BsBEST3102_04260	COG0494	nUDIX hydrolase
BsBEST3102_04270	COG0028	Belongs to the TPP enzyme family
BsBEST3102_04300	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3102_04310	COG2261	transglycosylase associated protein
BsBEST3102_04320	COG4876	unkown
BsBEST3102_04330	COG2217	Heavy metal translocating P-type atpase
BsBEST3102_04340	COG3729	General stress protein
BsBEST3102_04350	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3102_04360	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3102_04370	COG3546	catalase activity
BsBEST3102_04380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BsBEST3102_04390	COG3290	protein histidine kinase activity
BsBEST3102_04400	COG4565	transcriptional regulatory protein
BsBEST3102_04410	COG1301	dicarboxylic acid transport
BsBEST3102_04420	COG0628	permease
BsBEST3102_04430	COG1131	(ABC) transporter
BsBEST3102_04440	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3102_04460	COG1960	acyl-CoA dehydrogenase activity
BsBEST3102_04490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3102_04500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_04510	COG1181	Belongs to the D-alanine--D-alanine ligase family
BsBEST3102_04520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BsBEST3102_04530	COG0513	Belongs to the DEAD box helicase family
BsBEST3102_04540	COG3402	PFAM membrane-flanked domain
BsBEST3102_04550	COG3428	Bacterial PH domain
BsBEST3102_04560	COG0705	Rhomboid family
BsBEST3102_04570	COG0736	holo-[acyl-carrier-protein] synthase activity
BsBEST3102_04580	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BsBEST3102_04590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3102_04600	COG0864	Transcriptional regulator
BsBEST3102_04610	COG2337	Toxic component of a toxin-antitoxin (TA) module
BsBEST3102_04620	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3102_04630	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3102_04640	COG2172	sigma factor antagonist activity
BsBEST3102_04650	COG2208	phosphoserine phosphatase activity
BsBEST3102_04660	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3102_04670	COG2172	sigma factor antagonist activity
BsBEST3102_04680	COG1191	sigma factor activity
BsBEST3102_04690	COG2208	phosphoserine phosphatase activity
BsBEST3102_04720	COG1673	EVE domain
BsBEST3102_04730	COG1846	Transcriptional regulator
BsBEST3102_04740	COG2183	response to ionizing radiation
BsBEST3102_04750	COG3091	SprT-like family
BsBEST3102_04760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3102_04770	COG1522	sequence-specific DNA binding
BsBEST3102_04780	COG1522	sequence-specific DNA binding
BsBEST3102_04790	COG1335	isochorismatase
BsBEST3102_04800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3102_04810	COG2814	Major facilitator Superfamily
BsBEST3102_04850	COG0693	protein deglycase activity
BsBEST3102_04860	COG1278	Cold shock
BsBEST3102_04870	COG1329	Transcriptional regulator
BsBEST3102_04880	COG0697	spore germination
BsBEST3102_04890	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3102_04890	COG2207	Transcriptional regulator
BsBEST3102_04900	COG0697	spore germination
BsBEST3102_04910	COG2207	Transcriptional regulator
BsBEST3102_04910	COG3708	Transcriptional regulator
BsBEST3102_04920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3102_04930	COG0477	Major facilitator Superfamily
BsBEST3102_04950	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BsBEST3102_04970	COG0697	spore germination
BsBEST3102_04980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3102_04990	COG2030	dehydratase
BsBEST3102_05000	COG3545	Serine hydrolase
BsBEST3102_05010	COG1733	regulation of RNA biosynthetic process
BsBEST3102_05020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3102_05030	COG1733	regulation of RNA biosynthetic process
BsBEST3102_05040	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3102_05050	COG2814	Major facilitator Superfamily
BsBEST3102_05060	COG1309	transcriptional regulator
BsBEST3102_05080	COG0640	Transcriptional regulator
BsBEST3102_05090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3102_05100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3102_05110	COG0697	spore germination
BsBEST3102_05120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3102_05130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3102_05140	COG0640	Transcriptional regulator
BsBEST3102_05150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3102_05170	COG4585	Histidine kinase
BsBEST3102_05180	COG2197	response regulator
BsBEST3102_05190	COG2409	Drug exporters of the RND superfamily
BsBEST3102_05200	COG0596	Alpha beta hydrolase
BsBEST3102_05210	COG1811	Na channel or pump
BsBEST3102_05220	COG4978	Transcriptional regulator
BsBEST3102_05220	COG0789	Transcriptional regulator
BsBEST3102_05230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3102_05240	COG0778	Nitroreductase
BsBEST3102_05250	COG0346	lactoylglutathione lyase activity
BsBEST3102_05260	COG2259	Doxx family
BsBEST3102_05270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_05300	COG2323	membrane
BsBEST3102_05310	COG2323	membrane
BsBEST3102_05320	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3102_05350	COG1309	transcriptional regulator
BsBEST3102_05370	COG0456	acetyltransferase
BsBEST3102_05380	COG0488	(ABC) transporter
BsBEST3102_05390	COG1113	amino acid transport
BsBEST3102_05400	COG2318	DinB family
BsBEST3102_05410	COG1846	Transcriptional regulator
BsBEST3102_05420	COG1033	growth of symbiont in host cell
BsBEST3102_05420	COG2409	Drug exporters of the RND superfamily
BsBEST3102_05430	COG0778	Nitroreductase
BsBEST3102_05440	COG1846	Transcriptional regulator
BsBEST3102_05450	COG2814	Major facilitator Superfamily
BsBEST3102_05460	COG0730	response to heat
BsBEST3102_05470	COG1802	Transcriptional regulator
BsBEST3102_05480	COG1388	LysM domain
BsBEST3102_05480	COG3858	chitin binding
BsBEST3102_05490	COG1819	glycosyl
BsBEST3102_05510	COG1785	Belongs to the alkaline phosphatase family
BsBEST3102_05520	COG5646	InterPro IPR014922
BsBEST3102_05540	COG0454	-acetyltransferase
BsBEST3102_05550	COG1078	dGTPase activity
BsBEST3102_05560	COG1388	LysM domain
BsBEST3102_05570	COG2814	Major facilitator Superfamily
BsBEST3102_05580	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3102_05590	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3102_05600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3102_05610	COG2723	6-phospho-beta-galactosidase activity
BsBEST3102_05620	COG2188	Transcriptional regulator
BsBEST3102_05630	COG1940	carbohydrate kinase activity
BsBEST3102_05640	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3102_05650	COG4124	Belongs to the glycosyl hydrolase 26 family
BsBEST3102_05680	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BsBEST3102_05690	COG0802	atpase or kinase
BsBEST3102_05700	COG1214	PFAM Peptidase M22, glycoprotease
BsBEST3102_05710	COG0456	acetyltransferase
BsBEST3102_05720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BsBEST3102_05730	COG0488	(ABC) transporter
BsBEST3102_05740	COG0315	cyclic pyranopterin monophosphate synthase activity
BsBEST3102_05750	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BsBEST3102_05760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3102_05770	COG0805	protein transport
BsBEST3102_05790	COG1266	CAAX protease self-immunity
BsBEST3102_05810	COG0459	protein refolding
BsBEST3102_05840	COG3378	Phage plasmid primase P4 family
BsBEST3102_05870	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3102_05880	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3102_05910	COG1401	restriction endodeoxyribonuclease activity
BsBEST3102_05960	COG1073	alpha beta
BsBEST3102_05970	COG0457	Tetratricopeptide repeat
BsBEST3102_05980	COG1063	alcohol dehydrogenase
BsBEST3102_05990	COG2211	Major facilitator Superfamily
BsBEST3102_06000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3102_06010	COG1842	Phage shock protein A
BsBEST3102_06020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3102_06030	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BsBEST3102_06040	COG4260	virion core protein, lumpy skin disease virus
BsBEST3102_06060	COG2814	Major facilitator Superfamily
BsBEST3102_06070	COG1063	alcohol dehydrogenase
BsBEST3102_06080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BsBEST3102_06090	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3102_06120	COG2267	carboxylic ester hydrolase activity
BsBEST3102_06140	COG2132	Multicopper oxidase
BsBEST3102_06150	COG1113	amino acid transport
BsBEST3102_06160	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3102_06170	COG0714	Associated with various cellular activities
BsBEST3102_06180	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BsBEST3102_06190	COG1305	Transglutaminase-like
BsBEST3102_06200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BsBEST3102_06200	COG0519	Catalyzes the synthesis of GMP from XMP
BsBEST3102_06210	COG2252	PERMEase
BsBEST3102_06220	COG3064	Membrane
BsBEST3102_06240	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BsBEST3102_06260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BsBEST3102_06270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BsBEST3102_06280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BsBEST3102_06290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BsBEST3102_06300	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3102_06310	COG0047	phosphoribosylformylglycinamidine synthase activity
BsBEST3102_06320	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3102_06330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BsBEST3102_06340	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BsBEST3102_06350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BsBEST3102_06360	COG0138	bifunctional purine biosynthesis protein purh
BsBEST3102_06370	COG0151	Belongs to the GarS family
BsBEST3102_06380	COG1522	sequence-specific DNA binding
BsBEST3102_06390	COG0531	amino acid
BsBEST3102_06410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3102_06420	COG1470	cell adhesion involved in biofilm formation
BsBEST3102_06430	COG4496	protein, YerC YecD
BsBEST3102_06440	COG0069	glutamate synthase activity
BsBEST3102_06450	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BsBEST3102_06460	COG0210	DNA helicase
BsBEST3102_06470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BsBEST3102_06480	COG4851	CamS sex pheromone cAM373 precursor
BsBEST3102_06490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3102_06500	COG1285	pathogenesis
BsBEST3102_06510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3102_06520	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3102_06530	COG0154	amidase activity
BsBEST3102_06540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3102_06550	COG1309	transcriptional regulator
BsBEST3102_06560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BsBEST3102_06570	COG1597	lipid kinase activity
BsBEST3102_06580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3102_06590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3102_06600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3102_06610	COG1002	Type II restriction enzyme, methylase subunits
BsBEST3102_06620	COG1061	Type III restriction enzyme res subunit
BsBEST3102_06630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BsBEST3102_06670	COG5444	nuclease activity
BsBEST3102_06690	COG3391	amine dehydrogenase activity
BsBEST3102_06700	COG0457	Tetratricopeptide repeat
BsBEST3102_06720	COG0217	transcriptional regulatory protein
BsBEST3102_06740	COG1309	transcriptional regulator
BsBEST3102_06750	COG3631	Ketosteroid isomerase-related protein
BsBEST3102_06760	COG0702	epimerase
BsBEST3102_06790	COG3546	catalase activity
BsBEST3102_06800	COG0454	-acetyltransferase
BsBEST3102_06820	COG5578	integral membrane protein
BsBEST3102_06830	COG2972	Histidine kinase
BsBEST3102_06840	COG2207	Transcriptional regulator
BsBEST3102_06840	COG4753	response regulator
BsBEST3102_06850	COG1653	transport
BsBEST3102_06860	COG1175	transmembrane transport
BsBEST3102_06870	COG0395	ABC-type sugar transport system, permease component
BsBEST3102_06880	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3102_06890	COG2207	Transcriptional regulator
BsBEST3102_06900	COG2755	lipolytic protein G-D-S-L family
BsBEST3102_06920	COG5578	integral membrane protein
BsBEST3102_06930	COG3401	FG-GAP repeat protein
BsBEST3102_06940	COG3401	FG-GAP repeat protein
BsBEST3102_06950	COG2755	lipolytic protein G-D-S-L family
BsBEST3102_06960	COG1874	Beta-galactosidase
BsBEST3102_06980	COG1653	transport
BsBEST3102_06990	COG4209	transmembrane transport
BsBEST3102_07000	COG0395	ABC-type sugar transport system, permease component
BsBEST3102_07010	COG1486	melibiose metabolic process
BsBEST3102_07020	COG2323	membrane
BsBEST3102_07030	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3102_07040	COG0346	lactoylglutathione lyase activity
BsBEST3102_07060	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3102_07080	COG5583	Uncharacterized small protein (DUF2292)
BsBEST3102_07090	COG0670	Belongs to the BI1 family
BsBEST3102_07100	COG0697	spore germination
BsBEST3102_07110	COG1846	Transcriptional regulator
BsBEST3102_07120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3102_07140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3102_07140	COG2124	cytochrome p450
BsBEST3102_07150	COG1368	sulfuric ester hydrolase activity
BsBEST3102_07160	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BsBEST3102_07170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3102_07180	COG1442	glycosyl transferase family 8
BsBEST3102_07190	COG1216	Glycosyl transferase, family 2
BsBEST3102_07200	COG1442	glycosyl transferase family 8
BsBEST3102_07210	COG2223	nitrite transmembrane transporter activity
BsBEST3102_07220	COG1011	Hydrolase
BsBEST3102_07230	COG0531	amino acid
BsBEST3102_07240	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_07250	COG0840	transmembrane signaling receptor activity
BsBEST3102_07260	COG0488	(ABC) transporter
BsBEST3102_07280	COG0789	Transcriptional regulator
BsBEST3102_07290	COG2814	Major facilitator Superfamily
BsBEST3102_07310	COG0488	(ABC) transporter
BsBEST3102_07320	COG0513	Belongs to the DEAD box helicase family
BsBEST3102_07330	COG0456	acetyltransferase
BsBEST3102_07340	COG2130	NADP-dependent
BsBEST3102_07360	COG2211	Major facilitator Superfamily
BsBEST3102_07370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BsBEST3102_07380	COG1120	ATPase activity
BsBEST3102_07390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3102_07400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3102_07410	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3102_07440	COG3866	Pectate lyase
BsBEST3102_07450	COG0471	metal ion transport
BsBEST3102_07460	COG3290	protein histidine kinase activity
BsBEST3102_07470	COG4565	transcriptional regulatory protein
BsBEST3102_07480	COG3181	Tripartite tricarboxylate transporter family receptor
BsBEST3102_07490	COG2851	Citrate transporter
BsBEST3102_07500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3102_07510	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BsBEST3102_07520	COG1254	Belongs to the acylphosphatase family
BsBEST3102_07530	COG2258	MOSC domain
BsBEST3102_07570	COG0024	Methionine aminopeptidase
BsBEST3102_07580	COG1263	PTS System
BsBEST3102_07580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3102_07590	COG1368	sulfuric ester hydrolase activity
BsBEST3102_07610	COG1115	amino acid carrier protein
BsBEST3102_07620	COG0531	amino acid
BsBEST3102_07650	COG0697	spore germination
BsBEST3102_07660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3102_07660	COG1263	PTS System
BsBEST3102_07670	COG0366	Alpha amylase catalytic
BsBEST3102_07680	COG2188	Transcriptional regulator
BsBEST3102_07690	COG0778	Nitroreductase
BsBEST3102_07700	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3102_07710	COG0693	protein deglycase activity
BsBEST3102_07720	COG2814	Major facilitator Superfamily
BsBEST3102_07730	COG4840	Belongs to the UPF0435 family
BsBEST3102_07740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3102_07750	COG4980	gas vesicle protein
BsBEST3102_07760	COG1295	ribonuclease BN
BsBEST3102_07770	COG0477	Major facilitator Superfamily
BsBEST3102_07780	COG0387	Pfam Sodium calcium exchanger
BsBEST3102_07800	COG0668	transmembrane transport
BsBEST3102_07810	COG0535	radical SAM domain protein
BsBEST3102_07830	COG0726	polysaccharide deacetylase
BsBEST3102_07840	COG2084	Dehydrogenase
BsBEST3102_07850	COG0598	Magnesium transport protein CorA
BsBEST3102_07860	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3102_07870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3102_07890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3102_07900	COG4637	Psort location Cytoplasmic, score
BsBEST3102_07920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3102_07930	COG0022	dehydrogenase e1 component
BsBEST3102_07940	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3102_07950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3102_07960	COG3284	Transcriptional regulator
BsBEST3102_07980	COG1742	UPF0060 membrane protein
BsBEST3102_08030	COG4842	Belongs to the WXG100 family
BsBEST3102_08040	COG1486	melibiose metabolic process
BsBEST3102_08050	COG1737	Transcriptional regulator
BsBEST3102_08060	COG1263	PTS System
BsBEST3102_08060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3102_08070	COG1132	(ABC) transporter
BsBEST3102_08080	COG1132	(ABC) transporter
BsBEST3102_08090	COG2259	Doxx family
BsBEST3102_08100	COG2514	catechol 2,3-dioxygenase activity
BsBEST3102_08110	COG4977	sequence-specific DNA binding
BsBEST3102_08110	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3102_08120	COG2814	Major facilitator Superfamily
BsBEST3102_08130	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3102_08140	COG0673	inositol 2-dehydrogenase activity
BsBEST3102_08150	COG4585	Histidine kinase
BsBEST3102_08160	COG2197	response regulator
BsBEST3102_08170	COG1131	(ABC) transporter
BsBEST3102_08180	COG1511	domain protein
BsBEST3102_08180	COG0842	Transport permease protein
BsBEST3102_08190	COG0842	Transport permease protein
BsBEST3102_08200	COG1695	Transcriptional regulator
BsBEST3102_08210	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3102_08220	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BsBEST3102_08230	COG1309	transcriptional regulator
BsBEST3102_08240	COG2814	Major facilitator Superfamily
BsBEST3102_08250	COG2318	DinB family
BsBEST3102_08260	COG2814	Major facilitator Superfamily
BsBEST3102_08270	COG1846	Transcriptional regulator
BsBEST3102_08280	COG0392	lysyltransferase activity
BsBEST3102_08280	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BsBEST3102_08290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3102_08310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3102_08320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3102_08330	COG0384	phenazine biosynthesis protein PhzF
BsBEST3102_08340	COG0778	Nitroreductase
BsBEST3102_08360	COG1090	epimerase
BsBEST3102_08370	COG2137	regulation of response to DNA damage stimulus
BsBEST3102_08390	COG2814	Major facilitator Superfamily
BsBEST3102_08420	COG3103	Sh3 type 3 domain protein
BsBEST3102_08430	COG5658	integral membrane protein
BsBEST3102_08440	COG0596	Alpha beta hydrolase
BsBEST3102_08450	COG0463	Glycosyl transferase, family 2
BsBEST3102_08460	COG4485	Bacterial membrane protein, YfhO
BsBEST3102_08470	COG1988	membrane-bound metal-dependent
BsBEST3102_08480	COG1194	a g-specific adenine glycosylase
BsBEST3102_08500	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_08530	COG3557	Belongs to the UPF0374 family
BsBEST3102_08540	COG1132	(ABC) transporter
BsBEST3102_08550	COG4129	membrane
BsBEST3102_08560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3102_08570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BsBEST3102_08580	COG0735	belongs to the Fur family
BsBEST3102_08610	COG4326	sporulation control protein
BsBEST3102_08630	COG3340	Belongs to the peptidase S51 family
BsBEST3102_08640	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BsBEST3102_08650	COG0277	FAD linked oxidase domain protein
BsBEST3102_08670	COG0753	catalase activity
BsBEST3102_08680	COG1116	anion transmembrane transporter activity
BsBEST3102_08690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3102_08700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3102_08710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3102_08730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BsBEST3102_08750	COG1476	TRANSCRIPTIONal
BsBEST3102_08760	COG3382	B3 4 domain protein
BsBEST3102_08770	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BsBEST3102_08790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BsBEST3102_08800	COG0789	Transcriptional regulator
BsBEST3102_08810	COG1664	Polymer-forming cytoskeletal
BsBEST3102_08820	COG1664	Polymer-forming cytoskeletal
BsBEST3102_08830	COG2766	serine protein kinase
BsBEST3102_08840	COG2718	Belongs to the UPF0229 family
BsBEST3102_08850	COG1846	Transcriptional regulator
BsBEST3102_08860	COG1566	PFAM secretion protein HlyD family protein
BsBEST3102_08870	COG2814	Major facilitator Superfamily
BsBEST3102_08880	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3102_08910	COG1725	Transcriptional regulator
BsBEST3102_08920	COG1131	(ABC) transporter
BsBEST3102_08930	COG1131	(ABC) transporter
BsBEST3102_08940	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3102_08950	COG1278	Cold shock
BsBEST3102_08960	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3102_08970	COG3706	GGDEF domain
BsBEST3102_08980	COG1823	symporter activity
BsBEST3102_09020	COG5577	PFAM Coat F domain
BsBEST3102_09030	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3102_09030	COG1525	nuclease
BsBEST3102_09030	COG4085	toxin activity
BsBEST3102_09040	COG3764	Sortase (surface protein transpeptidase)
BsBEST3102_09050	COG0564	pseudouridine synthase activity
BsBEST3102_09070	COG0517	IMP dehydrogenase activity
BsBEST3102_09080	COG0517	IMP dehydrogenase activity
BsBEST3102_09090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3102_09100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3102_09100	COG3153	acetyltransferase
BsBEST3102_09120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3102_09130	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BsBEST3102_09140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BsBEST3102_09150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BsBEST3102_09160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BsBEST3102_09170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3102_09180	COG4585	Histidine kinase
BsBEST3102_09180	COG2203	Gaf domain
BsBEST3102_09190	COG2197	response regulator
BsBEST3102_09200	COG0431	NADPH-dependent FMN reductase
BsBEST3102_09230	COG1388	LysM domain
BsBEST3102_09230	COG0791	NLP P60 protein
BsBEST3102_09240	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3102_09250	COG0668	transmembrane transport
BsBEST3102_09260	COG2719	SpoVR family
BsBEST3102_09270	COG1785	Belongs to the alkaline phosphatase family
BsBEST3102_09280	COG0791	NLP P60 protein
BsBEST3102_09280	COG1388	LysM domain
BsBEST3102_09290	COG0583	DNA-binding transcription factor activity
BsBEST3102_09300	COG0372	Belongs to the citrate synthase family
BsBEST3102_09310	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_09320	COG0531	amino acid
BsBEST3102_09330	COG0733	neurotransmitter:sodium symporter activity
BsBEST3102_09340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3102_09350	COG0456	acetyltransferase
BsBEST3102_09380	COG1595	DNA-templated transcription, initiation
BsBEST3102_09390	COG0667	Aldo Keto reductase
BsBEST3102_09400	COG0204	Acyl-transferase
BsBEST3102_09410	COG1253	flavin adenine dinucleotide binding
BsBEST3102_09420	COG0789	Transcriptional regulator
BsBEST3102_09430	COG0436	Aminotransferase
BsBEST3102_09440	COG1253	flavin adenine dinucleotide binding
BsBEST3102_09450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3102_09460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3102_09470	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3102_09490	COG0668	transmembrane transport
BsBEST3102_09500	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BsBEST3102_09510	COG0726	polysaccharide deacetylase
BsBEST3102_09520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3102_09530	COG1757	Na H antiporter
BsBEST3102_09540	COG0589	response to stress
BsBEST3102_09560	COG1132	(ABC) transporter
BsBEST3102_09570	COG1132	(ABC) transporter
BsBEST3102_09580	COG0702	epimerase
BsBEST3102_09610	COG0189	ligase activity
BsBEST3102_09620	COG0189	ligase activity
BsBEST3102_09630	COG4399	Belongs to the UPF0754 family
BsBEST3102_09640	COG3679	Belongs to the UPF0342 family
BsBEST3102_09650	COG4335	DNA alkylation repair
BsBEST3102_09660	COG0561	phosphatase activity
BsBEST3102_09670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3102_09680	COG0475	glutathione-regulated potassium exporter activity
BsBEST3102_09690	COG0490	domain, Protein
BsBEST3102_09710	COG1024	Enoyl-CoA hydratase
BsBEST3102_09730	COG4152	abc transporter atp-binding protein
BsBEST3102_09740	COG1668	transmembrane transport
BsBEST3102_09750	COG0420	3'-5' exonuclease activity
BsBEST3102_09760	COG4717	serine-type aminopeptidase activity
BsBEST3102_09770	COG3481	metal-dependent phosphohydrolase, HD sub domain
BsBEST3102_09790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3102_09820	COG1846	Transcriptional regulator
BsBEST3102_09830	COG4980	gas vesicle protein
BsBEST3102_09850	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BsBEST3102_09860	COG0537	adenosine 5'-monophosphoramidase activity
BsBEST3102_09870	COG1131	(ABC) transporter
BsBEST3102_09880	COG4473	ABC transporter
BsBEST3102_09900	COG1473	amidohydrolase
BsBEST3102_09910	COG1473	amidohydrolase
BsBEST3102_09920	COG3069	C4-dicarboxylate transmembrane transporter activity
BsBEST3102_09930	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3102_09940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3102_09950	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BsBEST3102_09960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BsBEST3102_09970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BsBEST3102_09980	COG1309	transcriptional regulator
BsBEST3102_09990	COG1511	domain protein
BsBEST3102_10000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3102_10010	COG4377	Putative membrane peptidase family (DUF2324)
BsBEST3102_10030	COG1363	Peptidase, m42
BsBEST3102_10040	COG4405	Protein conserved in bacteria
BsBEST3102_10050	COG1301	dicarboxylic acid transport
BsBEST3102_10060	COG1234	tRNA 3'-trailer cleavage
BsBEST3102_10070	COG0095	Lipoate-protein ligase
BsBEST3102_10080	COG0702	epimerase
BsBEST3102_10090	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3102_10110	COG0501	Belongs to the peptidase M48B family
BsBEST3102_10130	COG0456	acetyltransferase
BsBEST3102_10140	COG0604	alcohol dehydrogenase
BsBEST3102_10150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3102_10160	COG0406	alpha-ribazole phosphatase activity
BsBEST3102_10170	COG0183	Belongs to the thiolase family
BsBEST3102_10180	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3102_10190	COG1268	BioY protein
BsBEST3102_10200	COG0840	transmembrane signaling receptor activity
BsBEST3102_10210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3102_10210	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3102_10220	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_10240	COG4903	ComK protein
BsBEST3102_10250	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_10270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3102_10300	COG0398	Pfam SNARE associated Golgi protein
BsBEST3102_10310	COG0681	Belongs to the peptidase S26 family
BsBEST3102_10320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3102_10330	COG1846	Transcriptional regulator
BsBEST3102_10340	COG0738	Major facilitator superfamily
BsBEST3102_10360	COG0673	inositol 2-dehydrogenase activity
BsBEST3102_10370	COG0561	phosphatase activity
BsBEST3102_10380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3102_10390	COG1609	Transcriptional regulator
BsBEST3102_10400	COG3180	Ammonia monooxygenase
BsBEST3102_10410	COG0477	Major facilitator Superfamily
BsBEST3102_10410	COG2814	Major facilitator Superfamily
BsBEST3102_10420	COG4533	DNA binding
BsBEST3102_10440	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BsBEST3102_10450	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BsBEST3102_10460	COG1074	ATP-dependent DNA helicase activity
BsBEST3102_10470	COG0420	3'-5' exonuclease activity
BsBEST3102_10480	COG0419	ATPase involved in DNA repair
BsBEST3102_10490	COG1403	HNH endonuclease
BsBEST3102_10570	COG0179	Fumarylacetoacetate (FAA) hydrolase
BsBEST3102_10590	COG1404	Belongs to the peptidase S8 family
BsBEST3102_10610	COG0367	asparagine synthase
BsBEST3102_10620	COG2318	DinB family
BsBEST3102_10630	COG1562	ergosterol biosynthetic process
BsBEST3102_10640	COG0534	Mate efflux family protein
BsBEST3102_10650	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3102_10650	COG2207	Transcriptional regulator
BsBEST3102_10660	COG1609	Transcriptional regulator
BsBEST3102_10670	COG0673	inositol 2-dehydrogenase activity
BsBEST3102_10680	COG2318	DinB family
BsBEST3102_10690	COG1279	arginine transmembrane transporter activity
BsBEST3102_10700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3102_10710	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3102_10720	COG2267	carboxylic ester hydrolase activity
BsBEST3102_10730	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3102_10740	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3102_10750	COG0175	sulfate reduction
BsBEST3102_10760	COG2045	Belongs to the ComB family
BsBEST3102_10770	COG1809	phosphosulfolactate synthase activity
BsBEST3102_10780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3102_10790	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3102_10800	COG2814	Major facilitator Superfamily
BsBEST3102_10810	COG0454	-acetyltransferase
BsBEST3102_10820	COG2153	protein acetylation
BsBEST3102_10830	COG0646	methionine synthase
BsBEST3102_10830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BsBEST3102_10840	COG1666	GTP binding
BsBEST3102_10850	COG2996	Protein conserved in bacteria
BsBEST3102_10890	COG1695	Transcriptional regulator
BsBEST3102_10920	COG3227	Zinc metalloprotease (Elastase)
BsBEST3102_10930	COG1307	EDD domain protein, DegV family
BsBEST3102_10940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3102_10970	COG0561	phosphatase activity
BsBEST3102_10980	COG1073	alpha beta
BsBEST3102_10990	COG2151	metal-sulfur cluster biosynthetic enzyme
BsBEST3102_11010	COG0277	FAD linked oxidase domain protein
BsBEST3102_11020	COG2271	Major facilitator Superfamily
BsBEST3102_11030	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BsBEST3102_11040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BsBEST3102_11060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3102_11070	COG0505	Belongs to the CarA family
BsBEST3102_11080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3102_11090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BsBEST3102_11120	COG2267	carboxylic ester hydrolase activity
BsBEST3102_11140	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3102_11170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3102_11180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3102_11190	COG5504	Zn-dependent protease
BsBEST3102_11200	COG0444	Belongs to the ABC transporter superfamily
BsBEST3102_11210	COG4608	Belongs to the ABC transporter superfamily
BsBEST3102_11240	COG0601	transmembrane transport
BsBEST3102_11250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3102_11270	COG0180	Tryptophanyl-tRNA synthetase
BsBEST3102_11280	COG4166	transmembrane transport
BsBEST3102_11290	COG0601	transmembrane transport
BsBEST3102_11300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3102_11310	COG0444	Belongs to the ABC transporter superfamily
BsBEST3102_11320	COG4608	Belongs to the ABC transporter superfamily
BsBEST3102_11330	COG2814	Major facilitator Superfamily
BsBEST3102_11340	COG0456	acetyltransferase
BsBEST3102_11350	COG1393	Belongs to the ArsC family
BsBEST3102_11360	COG0861	Integral membrane protein TerC family
BsBEST3102_11370	COG4862	establishment of competence for transformation
BsBEST3102_11380	COG1164	Oligoendopeptidase f
BsBEST3102_11400	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3102_11410	COG2346	COG2346, Truncated hemoglobins
BsBEST3102_11420	COG0741	lytic transglycosylase activity
BsBEST3102_11430	COG4116	CYTH
BsBEST3102_11450	COG2357	RelA SpoT domain protein
BsBEST3102_11460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3102_11470	COG0564	pseudouridine synthase activity
BsBEST3102_11480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BsBEST3102_11490	COG0569	domain protein
BsBEST3102_11490	COG0475	glutathione-regulated potassium exporter activity
BsBEST3102_11500	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BsBEST3102_11510	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3102_11520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3102_11530	COG2104	thiamine diphosphate biosynthetic process
BsBEST3102_11540	COG2022	thiamine diphosphate biosynthetic process
BsBEST3102_11550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3102_11560	COG0351	phosphomethylpyrimidine kinase
BsBEST3102_11570	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BsBEST3102_11680	COG0210	DNA helicase
BsBEST3102_11700	COG2153	protein acetylation
BsBEST3102_11710	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3102_11720	COG2382	esterase
BsBEST3102_11730	COG0626	cystathionine gamma-synthase activity
BsBEST3102_11740	COG0626	cystathionine gamma-synthase activity
BsBEST3102_11750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3102_11760	COG5505	Protein of unknown function (DUF819)
BsBEST3102_11820	COG3677	Transposase
BsBEST3102_11850	COG5484	DNA packaging
BsBEST3102_11860	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3102_11870	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_11890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3102_11890	COG3711	transcriptional antiterminator
BsBEST3102_11900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3102_11900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3102_11900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3102_11910	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3102_11930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3102_11950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3102_11990	COG0109	protoheme IX farnesyltransferase activity
BsBEST3102_12010	COG0726	polysaccharide deacetylase
BsBEST3102_12040	COG5504	Zn-dependent protease
BsBEST3102_12050	COG2205	protein histidine kinase activity
BsBEST3102_12070	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3102_12080	COG2427	Protein of unknown function (DUF1641)
BsBEST3102_12100	COG1051	belongs to the nudix hydrolase family
BsBEST3102_12120	COG2124	cytochrome p450
BsBEST3102_12130	COG1819	glycosyl
BsBEST3102_12150	COG1587	Uroporphyrinogen-III synthase
BsBEST3102_12160	COG0390	transport system, permease component
BsBEST3102_12170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3102_12180	COG0697	spore germination
BsBEST3102_12190	COG4297	protein containing double-stranded beta helix domain
BsBEST3102_12210	COG1252	NADH dehydrogenase
BsBEST3102_12220	COG1904	glucuronate isomerase
BsBEST3102_12230	COG2211	Major facilitator Superfamily
BsBEST3102_12240	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BsBEST3102_12250	COG1063	alcohol dehydrogenase
BsBEST3102_12260	COG1312	Catalyzes the dehydration of D-mannonate
BsBEST3102_12270	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_12280	COG2271	Major facilitator Superfamily
BsBEST3102_12290	COG1609	Transcriptional regulator
BsBEST3102_12300	COG0246	Mannitol dehydrogenase
BsBEST3102_12310	COG2721	sulfolactate sulfo-lyase activity
BsBEST3102_12320	COG0730	response to heat
BsBEST3102_12330	COG2318	DinB family
BsBEST3102_12340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3102_12350	COG0457	Tetratricopeptide repeat
BsBEST3102_12370	COG2350	Protein conserved in bacteria
BsBEST3102_12380	COG1388	LysM domain
BsBEST3102_12380	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_12380	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_12400	COG4195	phage-related replication protein
BsBEST3102_12410	COG3546	catalase activity
BsBEST3102_12420	COG2856	Zn peptidase
BsBEST3102_12430	COG1396	sequence-specific DNA binding
BsBEST3102_12450	COG1522	sequence-specific DNA binding
BsBEST3102_12460	COG1484	DNA-dependent DNA replication
BsBEST3102_12500	COG1595	DNA-templated transcription, initiation
BsBEST3102_12510	COG3728	DNA packaging
BsBEST3102_12510	COG5484	DNA packaging
BsBEST3102_12520	COG1783	phage Terminase large subunit
BsBEST3102_12530	COG5518	Phage portal protein
BsBEST3102_12540	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3102_12550	COG4653	Phage capsid family
BsBEST3102_12650	COG3953	SLT domain
BsBEST3102_12650	COG5412	phage tail tape measure protein
BsBEST3102_12660	COG1652	LysM domain
BsBEST3102_12670	COG4193	domain, Protein
BsBEST3102_12690	COG3628	GPW Gp25 family protein
BsBEST3102_12700	COG3299	homolog of phage Mu protein gp47
BsBEST3102_12710	COG3778	Protein conserved in bacteria
BsBEST3102_12790	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_12790	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_12820	COG0306	phosphate transporter
BsBEST3102_12830	COG1392	Phosphate transport regulator
BsBEST3102_12840	COG0531	amino acid
BsBEST3102_12850	COG0346	lactoylglutathione lyase activity
BsBEST3102_12870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3102_12880	COG0463	Glycosyl transferase, family 2
BsBEST3102_12900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3102_12910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3102_12920	COG2362	D-Aminopeptidase
BsBEST3102_12930	COG0601	transmembrane transport
BsBEST3102_12940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3102_12950	COG0444	Belongs to the ABC transporter superfamily
BsBEST3102_12960	COG4166	transmembrane transport
BsBEST3102_12970	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3102_12980	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3102_12990	COG0791	NLP P60 protein
BsBEST3102_13000	COG4608	Belongs to the ABC transporter superfamily
BsBEST3102_13010	COG2706	6-phosphogluconolactonase activity
BsBEST3102_13020	COG1834	amidinotransferase
BsBEST3102_13030	COG1607	acyl-coa hydrolase
BsBEST3102_13040	COG1017	nitric oxide dioxygenase activity
BsBEST3102_13040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BsBEST3102_13060	COG2323	membrane
BsBEST3102_13070	COG2318	DinB family
BsBEST3102_13080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3102_13090	COG2076	Multidrug Resistance protein
BsBEST3102_13100	COG2076	Multidrug Resistance protein
BsBEST3102_13110	COG0788	formyltetrahydrofolate deformylase activity
BsBEST3102_13120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3102_13130	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BsBEST3102_13140	COG1764	response to oxidative stress
BsBEST3102_13150	COG1846	Transcriptional regulator
BsBEST3102_13160	COG1764	response to oxidative stress
BsBEST3102_13180	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3102_13190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3102_13200	COG1404	Belongs to the peptidase S8 family
BsBEST3102_13210	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3102_13220	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3102_13230	COG1122	ATPase activity
BsBEST3102_13240	COG4721	ABC-type cobalt transport system, permease component
BsBEST3102_13260	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_13270	COG3850	Histidine kinase
BsBEST3102_13270	COG5002	protein histidine kinase activity
BsBEST3102_13280	COG3212	peptidase
BsBEST3102_13290	COG3212	peptidase
BsBEST3102_13320	COG2239	Acts as a magnesium transporter
BsBEST3102_13330	COG0789	Transcriptional regulator
BsBEST3102_13360	COG1846	Transcriptional regulator
BsBEST3102_13370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3102_13380	COG0726	polysaccharide deacetylase
BsBEST3102_13390	COG1408	metallophosphoesterase
BsBEST3102_13410	COG0463	Glycosyl transferase, family 2
BsBEST3102_13420	COG3285	dna ligase
BsBEST3102_13420	COG1793	dna ligase
BsBEST3102_13430	COG1793	dna ligase
BsBEST3102_13430	COG3285	dna ligase
BsBEST3102_13440	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BsBEST3102_13450	COG3300	MHYT domain
BsBEST3102_13450	COG5001	Diguanylate cyclase
BsBEST3102_13460	COG0586	Pfam SNARE associated Golgi protein
BsBEST3102_13470	COG0861	Integral membrane protein TerC family
BsBEST3102_13480	COG1191	sigma factor activity
BsBEST3102_13520	COG0501	Belongs to the peptidase M48B family
BsBEST3102_13530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3102_13560	COG3594	Acyltransferase
BsBEST3102_13570	COG5002	protein histidine kinase activity
BsBEST3102_13580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3102_13600	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BsBEST3102_13610	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BsBEST3102_13620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3102_13630	COG0436	Aminotransferase
BsBEST3102_13640	COG1850	ribulose-bisphosphate carboxylase activity
BsBEST3102_13650	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BsBEST3102_13660	COG0235	Class ii aldolase
BsBEST3102_13670	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BsBEST3102_13680	COG3339	Conserved Protein
BsBEST3102_13710	COG3852	Histidine kinase
BsBEST3102_13720	COG1846	Transcriptional regulator
BsBEST3102_13730	COG1360	Flagellar Motor Protein
BsBEST3102_13740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3102_13750	COG0542	response to heat
BsBEST3102_13760	COG3949	Membrane
BsBEST3102_13770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BsBEST3102_13780	COG0720	synthase
BsBEST3102_13790	COG0602	queuosine metabolic process
BsBEST3102_13800	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BsBEST3102_13810	COG1733	regulation of RNA biosynthetic process
BsBEST3102_13820	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_13830	COG4641	Protein conserved in bacteria
BsBEST3102_13830	COG1388	LysM domain
BsBEST3102_13840	COG1388	LysM domain
BsBEST3102_13850	COG3858	chitin binding
BsBEST3102_13860	COG3858	chitin binding
BsBEST3102_13880	COG4873	Protein conserved in bacteria
BsBEST3102_13900	COG3773	Cell wall hydrolase
BsBEST3102_13910	COG2244	polysaccharide biosynthetic process
BsBEST3102_13920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_13930	COG2217	Heavy metal translocating P-type atpase
BsBEST3102_13950	COG0006	proline dipeptidase activity
BsBEST3102_13970	COG1609	Transcriptional regulator
BsBEST3102_13980	COG3711	transcriptional antiterminator
BsBEST3102_13990	COG1263	PTS System
BsBEST3102_13990	COG2190	(PTS) system
BsBEST3102_13990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3102_14000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3102_14010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BsBEST3102_14030	COG1533	DNA photolyase activity
BsBEST3102_14040	COG0456	acetyltransferase
BsBEST3102_14050	COG0840	transmembrane signaling receptor activity
BsBEST3102_14060	COG2084	Dehydrogenase
BsBEST3102_14070	COG2340	Cysteine-rich secretory protein family
BsBEST3102_14080	COG0768	penicillin binding
BsBEST3102_14090	COG4191	Histidine kinase
BsBEST3102_14100	COG0436	Aminotransferase
BsBEST3102_14120	COG0784	Response regulator, receiver
BsBEST3102_14120	COG0835	chemotaxis
BsBEST3102_14140	COG2814	Major facilitator Superfamily
BsBEST3102_14150	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3102_14160	COG1408	metallophosphoesterase
BsBEST3102_14170	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_14180	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_14190	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_14210	COG2200	EAL domain
BsBEST3102_14220	COG4703	Protein of unknown function (DUF1797)
BsBEST3102_14230	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BsBEST3102_14250	COG0517	IMP dehydrogenase activity
BsBEST3102_14260	COG0583	DNA-binding transcription factor activity
BsBEST3102_14270	COG0716	FMN binding
BsBEST3102_14290	COG0716	FMN binding
BsBEST3102_14300	COG2171	N-acyltransferase activity
BsBEST3102_14310	COG1473	amidohydrolase
BsBEST3102_14330	COG0668	transmembrane transport
BsBEST3102_14340	COG0450	alkyl hydroperoxide reductase
BsBEST3102_14350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_14380	COG0746	molybdenum cofactor guanylyltransferase activity
BsBEST3102_14390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3102_14400	COG0303	'Molybdopterin
BsBEST3102_14410	COG1763	Mo-molybdopterin cofactor biosynthetic process
BsBEST3102_14420	COG0314	molybdopterin synthase activity
BsBEST3102_14430	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BsBEST3102_14440	COG1132	(ABC) transporter
BsBEST3102_14450	COG1132	(ABC) transporter
BsBEST3102_14470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3102_14480	COG1136	(ABC) transporter
BsBEST3102_14490	COG0577	efflux transmembrane transporter activity
BsBEST3102_14500	COG1349	DNA-binding transcription factor activity
BsBEST3102_14510	COG1105	Belongs to the carbohydrate kinase PfkB family
BsBEST3102_14520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3102_14520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3102_14520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3102_14530	COG0681	Belongs to the peptidase S26 family
BsBEST3102_14550	COG0488	(ABC) transporter
BsBEST3102_14560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3102_14570	COG2309	aminopeptidase activity
BsBEST3102_14590	COG1077	Cell shape determining protein MreB Mrl
BsBEST3102_14600	COG2002	toxin-antitoxin pair type II binding
BsBEST3102_14610	COG3852	Histidine kinase
BsBEST3102_14620	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BsBEST3102_14620	COG2105	PFAM AIG2 family protein
BsBEST3102_14630	COG0569	domain protein
BsBEST3102_14640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3102_14650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3102_14660	COG5503	Protein of unknown function (DUF1447)
BsBEST3102_14670	COG0561	phosphatase activity
BsBEST3102_14680	COG0242	peptide deformylase activity
BsBEST3102_14700	COG0497	DNA recombination
BsBEST3102_14710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3102_14720	COG0022	dehydrogenase e1 component
BsBEST3102_14730	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3102_14740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3102_14750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_14760	COG1982	Orn Lys Arg decarboxylase major
BsBEST3102_14770	COG4476	Belongs to the UPF0223 family
BsBEST3102_14780	COG4493	Belongs to the UPF0637 family
BsBEST3102_14800	COG0483	inositol monophosphate 1-phosphatase activity
BsBEST3102_14820	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BsBEST3102_14860	COG1595	DNA-templated transcription, initiation
BsBEST3102_14900	COG1217	gtp-binding protein TYPA
BsBEST3102_14920	COG4896	Protein conserved in bacteria
BsBEST3102_14940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BsBEST3102_14950	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3102_14960	COG2066	Belongs to the glutaminase family
BsBEST3102_14970	COG4838	Belongs to the UPF0358 family
BsBEST3102_14990	COG0772	Belongs to the SEDS family
BsBEST3102_15000	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BsBEST3102_15010	COG1612	heme a metabolic process
BsBEST3102_15020	COG0109	protoheme IX farnesyltransferase activity
BsBEST3102_15030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3102_15030	COG2010	Cytochrome c
BsBEST3102_15040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3102_15050	COG1845	cytochrome c oxidase, subunit III
BsBEST3102_15060	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3102_15070	COG3336	cytochrome c oxidase
BsBEST3102_15090	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BsBEST3102_15100	COG2340	Cysteine-rich secretory protein family
BsBEST3102_15130	COG3679	Belongs to the UPF0342 family
BsBEST3102_15140	COG4471	UPF0298 protein
BsBEST3102_15150	COG0742	ribosomal rna small subunit methyltransferase
BsBEST3102_15160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BsBEST3102_15170	COG3314	Sporulation integral membrane protein YlbJ
BsBEST3102_15180	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3102_15190	COG3480	Lon protease (S16) C-terminal proteolytic domain
BsBEST3102_15200	COG1323	Belongs to the UPF0348 family
BsBEST3102_15210	COG1399	metal-binding, possibly nucleic acid-binding protein
BsBEST3102_15240	COG0454	-acetyltransferase
BsBEST3102_15250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3102_15260	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BsBEST3102_15270	COG2001	Belongs to the MraZ family
BsBEST3102_15280	COG0275	rRNA processing
BsBEST3102_15290	COG4839	cell division protein FtsL
BsBEST3102_15300	COG0768	penicillin binding
BsBEST3102_15310	COG0768	penicillin binding
BsBEST3102_15320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BsBEST3102_15330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3102_15340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3102_15350	COG0772	Belongs to the SEDS family
BsBEST3102_15360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3102_15370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BsBEST3102_15380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BsBEST3102_15390	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3102_15400	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3102_15410	COG3856	small basic protein
BsBEST3102_15420	COG0849	cell division
BsBEST3102_15430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BsBEST3102_15440	COG1404	Belongs to the peptidase S8 family
BsBEST3102_15440	COG4412	M6 family metalloprotease domain protein
BsBEST3102_15460	COG1191	sigma factor activity
BsBEST3102_15470	COG1191	sigma factor activity
BsBEST3102_15480	COG1119	ATPase activity
BsBEST3102_15490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3102_15500	COG1873	PFAM PRC-barrel domain
BsBEST3102_15510	COG1496	oxidoreductase activity
BsBEST3102_15520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BsBEST3102_15530	COG1799	cell septum assembly
BsBEST3102_15540	COG0762	integral membrane protein
BsBEST3102_15550	COG2302	S4 RNA-binding domain
BsBEST3102_15560	COG3599	regulation of cell shape
BsBEST3102_15570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BsBEST3102_15580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3102_15590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BsBEST3102_15600	COG0564	pseudouridine synthase activity
BsBEST3102_15610	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BsBEST3102_15620	COG2233	PERMEase
BsBEST3102_15630	COG0540	Belongs to the ATCase OTCase family
BsBEST3102_15640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3102_15650	COG0505	Belongs to the CarA family
BsBEST3102_15660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3102_15670	COG0543	2 iron, 2 sulfur cluster binding
BsBEST3102_15680	COG0167	dihydroorotate dehydrogenase activity
BsBEST3102_15690	COG0284	orotidine-5'-phosphate decarboxylase activity
BsBEST3102_15700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BsBEST3102_15710	COG0175	sulfate reduction
BsBEST3102_15720	COG0306	phosphate transporter
BsBEST3102_15730	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3102_15740	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3102_15750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3102_15760	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BsBEST3102_15770	COG1648	precorrin-2 dehydrogenase activity
BsBEST3102_15780	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BsBEST3102_15790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3102_15800	COG1561	YicC-like family, N-terminal region
BsBEST3102_15820	COG0194	GDP metabolic process
BsBEST3102_15830	COG1758	RNA polymerase activity
BsBEST3102_15840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3102_15850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3102_15860	COG0242	peptide deformylase activity
BsBEST3102_15870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BsBEST3102_15880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3102_15880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BsBEST3102_15890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BsBEST3102_15900	COG0631	protein serine/threonine phosphatase activity
BsBEST3102_15910	COG0515	serine threonine protein kinase
BsBEST3102_15910	COG2815	serine threonine protein kinase
BsBEST3102_15920	COG1162	GTPase activity
BsBEST3102_15930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BsBEST3102_15940	COG1564	THIamine pyrophosphokinase
BsBEST3102_15950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BsBEST3102_15960	COG1302	Protein conserved in bacteria
BsBEST3102_15970	COG1461	Dihydroxyacetone kinase
BsBEST3102_15980	COG1760	l-serine dehydratase
BsBEST3102_15990	COG1760	l-serine dehydratase
BsBEST3102_16000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BsBEST3102_16010	COG1349	DNA-binding transcription factor activity
BsBEST3102_16010	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3102_16020	COG0416	fatty acid biosynthetic process
BsBEST3102_16030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3102_16040	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_16060	COG0571	ribonuclease III activity
BsBEST3102_16070	COG1196	nuclear chromosome segregation
BsBEST3102_16080	COG0552	protein localization to endoplasmic reticulum
BsBEST3102_16100	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BsBEST3102_16110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BsBEST3102_16120	COG0228	four-way junction DNA binding
BsBEST3102_16130	COG1837	Belongs to the UPF0109 family
BsBEST3102_16150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BsBEST3102_16160	COG0336	Belongs to the RNA methyltransferase TrmD family
BsBEST3102_16170	COG0335	large ribosomal subunit rRNA binding
BsBEST3102_16180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3102_16190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3102_16210	COG2257	FlhB HrpN YscU SpaS Family
BsBEST3102_16220	COG0045	succinate-CoA ligase (ADP-forming) activity
BsBEST3102_16230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BsBEST3102_16240	COG0758	DNA mediated transformation
BsBEST3102_16250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3102_16260	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BsBEST3102_16270	COG4974	Belongs to the 'phage' integrase family
BsBEST3102_16280	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BsBEST3102_16290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BsBEST3102_16300	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3102_16310	COG1815	bacterial-type flagellum-dependent cell motility
BsBEST3102_16320	COG1558	bacterial-type flagellum-dependent cell motility
BsBEST3102_16330	COG1677	Flagellar hook-basal body complex protein FliE
BsBEST3102_16340	COG1766	The M ring may be actively involved in energy transduction
BsBEST3102_16350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3102_16360	COG1317	bacterial-type flagellum organization
BsBEST3102_16370	COG1157	protein secretion by the type III secretion system
BsBEST3102_16380	COG2882	bacterial-type flagellum organization
BsBEST3102_16390	COG3334	PFAM MgtE intracellular
BsBEST3102_16400	COG3144	bacterial-type flagellum assembly
BsBEST3102_16410	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BsBEST3102_16420	COG4786	Flagellar basal body rod
BsBEST3102_16430	COG1582	Flagellar protein (FlbD)
BsBEST3102_16440	COG1580	Controls the rotational direction of flagella during chemotaxis
BsBEST3102_16450	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3102_16460	COG1776	CheC inhibitor of MCP methylation
BsBEST3102_16460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3102_16470	COG2201	protein-glutamate methylesterase activity
BsBEST3102_16480	COG3190	flagellar
BsBEST3102_16490	COG1338	Plays a role in the flagellum-specific transport system
BsBEST3102_16500	COG1987	bacterial-type flagellum assembly
BsBEST3102_16510	COG1684	flagellar biosynthetic protein fliR
BsBEST3102_16520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3102_16530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3102_16540	COG1419	protein localization to endoplasmic reticulum
BsBEST3102_16550	COG0455	bacterial-type flagellum organization
BsBEST3102_16560	COG2201	protein-glutamate methylesterase activity
BsBEST3102_16570	COG0643	Histidine kinase
BsBEST3102_16570	COG2198	Histidine kinase
BsBEST3102_16580	COG0835	chemotaxis
BsBEST3102_16590	COG1776	CheC inhibitor of MCP methylation
BsBEST3102_16600	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BsBEST3102_16610	COG1191	sigma factor activity
BsBEST3102_16630	COG0052	Belongs to the universal ribosomal protein uS2 family
BsBEST3102_16640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BsBEST3102_16650	COG0528	UMP kinase activity
BsBEST3102_16660	COG0233	cytoplasmic translational termination
BsBEST3102_16670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BsBEST3102_16680	COG4589	Belongs to the CDS family
BsBEST3102_16690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BsBEST3102_16700	COG0750	zinc metalloprotease
BsBEST3102_16710	COG0442	prolyl-tRNA aminoacylation
BsBEST3102_16720	COG2176	DNA-directed DNA polymerase activity
BsBEST3102_16730	COG0779	Required for maturation of 30S ribosomal subunits
BsBEST3102_16740	COG0195	Participates in both transcription termination and antitermination
BsBEST3102_16750	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BsBEST3102_16760	COG1358	cellular component organization or biogenesis
BsBEST3102_16770	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BsBEST3102_16780	COG1550	Protein conserved in bacteria
BsBEST3102_16790	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BsBEST3102_16800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BsBEST3102_16810	COG0196	riboflavin kinase activity
BsBEST3102_16820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BsBEST3102_16830	COG1185	polyribonucleotide nucleotidyltransferase activity
BsBEST3102_16840	COG0726	polysaccharide deacetylase
BsBEST3102_16850	COG0612	Peptidase, M16
BsBEST3102_16860	COG1873	PFAM PRC-barrel domain
BsBEST3102_16870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3102_16880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3102_16890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BsBEST3102_16900	COG0527	aspartate kinase activity
BsBEST3102_16910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3102_16920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3102_16930	COG0740	serine-type endopeptidase activity
BsBEST3102_16950	COG4980	gas vesicle protein
BsBEST3102_16950	COG1674	ftsk spoiiie
BsBEST3102_16960	COG2188	Transcriptional regulator
BsBEST3102_16970	COG2814	Major facilitator Superfamily
BsBEST3102_16980	COG0612	Peptidase, M16
BsBEST3102_16990	COG0612	Peptidase, M16
BsBEST3102_17000	COG0300	oxidoreductase activity
BsBEST3102_17040	COG1426	Protein conserved in bacteria
BsBEST3102_17050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BsBEST3102_17060	COG1058	Belongs to the CinA family
BsBEST3102_17060	COG1546	Belongs to the CinA family
BsBEST3102_17070	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BsBEST3102_17080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3102_17090	COG1418	mRNA catabolic process
BsBEST3102_17100	COG1692	metallophosphoesterase
BsBEST3102_17110	COG2359	stage V sporulation protein S
BsBEST3102_17120	COG1063	alcohol dehydrogenase
BsBEST3102_17130	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3102_17140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3102_17150	COG4550	Control of competence regulator ComK, YlbF/YmcA
BsBEST3102_17170	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BsBEST3102_17180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BsBEST3102_17210	COG3226	Transcriptional regulator
BsBEST3102_17220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3102_17240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3102_17250	COG3321	synthase
BsBEST3102_17260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3102_17260	COG2070	2-Nitropropane dioxygenase
BsBEST3102_17270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3102_17280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3102_17290	COG3425	synthase
BsBEST3102_17300	COG1024	Enoyl-CoA hydratase
BsBEST3102_17310	COG1024	Enoyl-CoA hydratase
BsBEST3102_17320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_17320	COG3321	synthase
BsBEST3102_17320	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_17320	COG0300	oxidoreductase activity
BsBEST3102_17320	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3102_17330	COG4221	oxidoreductase activity
BsBEST3102_17330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3102_17330	COG0300	oxidoreductase activity
BsBEST3102_17330	COG3321	synthase
BsBEST3102_17340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_17340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3102_17340	COG3321	synthase
BsBEST3102_17340	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_17340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3102_17350	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_17350	COG4221	oxidoreductase activity
BsBEST3102_17350	COG3321	synthase
BsBEST3102_17350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_17360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_17360	COG4221	oxidoreductase activity
BsBEST3102_17360	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_17360	COG3321	synthase
BsBEST3102_17370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BsBEST3102_17370	COG3321	synthase
BsBEST3102_17370	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3102_17370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3102_17380	COG2124	cytochrome p450
BsBEST3102_17400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3102_17410	COG1404	Belongs to the peptidase S8 family
BsBEST3102_17420	COG4195	phage-related replication protein
BsBEST3102_17430	COG1764	response to oxidative stress
BsBEST3102_17440	COG2076	Multidrug Resistance protein
BsBEST3102_17450	COG2076	Multidrug Resistance protein
BsBEST3102_17480	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BsBEST3102_17490	COG1923	regulation of RNA biosynthetic process
BsBEST3102_17520	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3102_17530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3102_17540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3102_17550	COG4112	unkown
BsBEST3102_17560	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_17570	COG0464	growth
BsBEST3102_17580	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BsBEST3102_17590	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BsBEST3102_17600	COG0789	Transcriptional regulator
BsBEST3102_17610	COG0174	glutamine synthetase
BsBEST3102_17650	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3102_17670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3102_17720	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3102_17730	COG2211	Major facilitator Superfamily
BsBEST3102_17740	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3102_17750	COG1940	carbohydrate kinase activity
BsBEST3102_17760	COG2115	Belongs to the xylose isomerase family
BsBEST3102_17770	COG1070	Carbohydrate kinase
BsBEST3102_17780	COG1525	nuclease
BsBEST3102_17790	COG2814	Major facilitator Superfamily
BsBEST3102_17800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3102_17820	COG0756	dUTP diphosphatase activity
BsBEST3102_17870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3102_17920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3102_17940	COG3832	glyoxalase III activity
BsBEST3102_17960	COG0697	spore germination
BsBEST3102_17970	COG0531	amino acid
BsBEST3102_18030	COG4195	phage-related replication protein
BsBEST3102_18050	COG0346	lactoylglutathione lyase activity
BsBEST3102_18060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BsBEST3102_18070	COG1388	LysM domain
BsBEST3102_18080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3102_18090	COG4224	UPF0291 protein
BsBEST3102_18100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BsBEST3102_18120	COG3763	UPF0154 protein
BsBEST3102_18140	COG0785	Cytochrome C biogenesis protein
BsBEST3102_18150	COG2201	protein-glutamate methylesterase activity
BsBEST3102_18160	COG4846	Membrane protein involved in cytochrome C biogenesis
BsBEST3102_18180	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3102_18210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BsBEST3102_18220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_18260	COG0824	Thioesterase
BsBEST3102_18280	COG4841	protein insertion into membrane
BsBEST3102_18290	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BsBEST3102_18300	COG1832	CoA-binding protein
BsBEST3102_18310	COG0187	DNA topoisomerase II activity
BsBEST3102_18320	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3102_18340	COG1115	amino acid carrier protein
BsBEST3102_18350	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BsBEST3102_18370	COG5520	Belongs to the glycosyl hydrolase 30 family
BsBEST3102_18380	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3102_18390	COG2246	polysaccharide biosynthetic process
BsBEST3102_18400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3102_18410	COG0586	Pfam SNARE associated Golgi protein
BsBEST3102_18420	COG2404	hydrolase activity, acting on ester bonds
BsBEST3102_18430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3102_18440	COG1024	Enoyl-CoA hydratase
BsBEST3102_18450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3102_18460	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3102_18470	COG0439	Biotin carboxylase
BsBEST3102_18480	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3102_18490	COG1960	acyl-CoA dehydrogenase activity
BsBEST3102_18510	COG1649	PFAM Uncharacterised BCR, COG1649
BsBEST3102_18530	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3102_18530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_18540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_18550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_18560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_18570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_18580	COG2027	D-alanyl-D-alanine carboxypeptidase
BsBEST3102_18590	COG2017	converts alpha-aldose to the beta-anomer
BsBEST3102_18600	COG0534	Mate efflux family protein
BsBEST3102_18620	COG0582	viral genome integration into host DNA
BsBEST3102_18630	COG0166	Belongs to the GPI family
BsBEST3102_18640	COG0405	Gamma-glutamyltransferase
BsBEST3102_18650	COG0583	DNA-binding transcription factor activity
BsBEST3102_18660	COG0604	alcohol dehydrogenase
BsBEST3102_18670	COG0493	'glutamate synthase
BsBEST3102_18680	COG0067	glutamate synthase
BsBEST3102_18680	COG0069	glutamate synthase activity
BsBEST3102_18680	COG0070	glutamate synthase
BsBEST3102_18690	COG0583	DNA-binding transcription factor activity
BsBEST3102_18700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3102_18710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3102_18730	COG0300	oxidoreductase activity
BsBEST3102_18740	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3102_18760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3102_18770	COG2814	Major facilitator Superfamily
BsBEST3102_18780	COG1070	Carbohydrate kinase
BsBEST3102_18790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3102_18800	COG0243	molybdopterin cofactor binding
BsBEST3102_18850	COG5278	phosphoserine phosphatase activity
BsBEST3102_18850	COG0840	transmembrane signaling receptor activity
BsBEST3102_18860	COG2368	4-hydroxyphenylacetate
BsBEST3102_18870	COG4305	rare lipoprotein A
BsBEST3102_18880	COG3619	membrane
BsBEST3102_18890	COG3866	Pectate lyase
BsBEST3102_18900	COG2135	peptidase activity
BsBEST3102_18920	COG2140	Oxalate decarboxylase
BsBEST3102_18940	COG0456	acetyltransferase
BsBEST3102_18970	COG2720	vancomycin resistance protein
BsBEST3102_18990	COG3655	Transcriptional regulator
BsBEST3102_19000	COG3739	integral membrane protein
BsBEST3102_19010	COG0583	DNA-binding transcription factor activity
BsBEST3102_19020	COG0697	spore germination
BsBEST3102_19040	COG0693	protein deglycase activity
BsBEST3102_19050	COG2367	Beta-lactamase
BsBEST3102_19090	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3102_19090	COG3848	Pyruvate phosphate dikinase
BsBEST3102_19100	COG0726	polysaccharide deacetylase
BsBEST3102_19110	COG2314	TM2 domain
BsBEST3102_19120	COG1396	sequence-specific DNA binding
BsBEST3102_19150	COG2135	peptidase activity
BsBEST3102_19210	COG0457	Tetratricopeptide repeat
BsBEST3102_19230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3102_19240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3102_19270	COG5290	Psort location Cytoplasmic, score
BsBEST3102_19320	COG5444	nuclease activity
BsBEST3102_19330	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3102_19340	COG1231	oxidoreductase activity
BsBEST3102_19350	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3102_19360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3102_19370	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3102_19370	COG2207	Transcriptional regulator
BsBEST3102_19380	COG0456	acetyltransferase
BsBEST3102_19390	COG1309	transcriptional regulator
BsBEST3102_19400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3102_19410	COG3708	Transcriptional regulator
BsBEST3102_19420	COG2378	regulation of single-species biofilm formation
BsBEST3102_19440	COG0640	Transcriptional regulator
BsBEST3102_19450	COG0741	lytic transglycosylase activity
BsBEST3102_19460	COG2322	membrane
BsBEST3102_19490	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3102_19500	COG3239	Fatty acid desaturase
BsBEST3102_19510	COG4585	Histidine kinase
BsBEST3102_19520	COG2197	response regulator
BsBEST3102_19530	COG1388	LysM domain
BsBEST3102_19530	COG3584	3D domain protein
BsBEST3102_19540	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3102_19550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3102_19560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3102_19590	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3102_19640	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_19650	COG1657	PFAM Prenyltransferase squalene oxidase
BsBEST3102_19660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3102_19670	COG0733	neurotransmitter:sodium symporter activity
BsBEST3102_19680	COG0385	Bile acid
BsBEST3102_19690	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3102_19700	COG0567	Dehydrogenase, E1 component
BsBEST3102_19710	COG4548	von Willebrand factor, type A
BsBEST3102_19720	COG0714	Associated with various cellular activities
BsBEST3102_19730	COG2032	superoxide dismutase activity
BsBEST3102_19740	COG0791	NLP P60 protein
BsBEST3102_19740	COG1388	LysM domain
BsBEST3102_19750	COG1819	glycosyl
BsBEST3102_19760	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3102_19770	COG0534	Mate efflux family protein
BsBEST3102_19780	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3102_19790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3102_19800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3102_19820	COG2962	Rard protein
BsBEST3102_19850	COG2610	gluconate transmembrane transporter activity
BsBEST3102_19860	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3102_19870	COG1733	regulation of RNA biosynthetic process
BsBEST3102_19880	COG0778	Nitroreductase
BsBEST3102_19890	COG0400	carboxylic ester hydrolase activity
BsBEST3102_19900	COG0346	lactoylglutathione lyase activity
BsBEST3102_19920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3102_19930	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_19930	COG0793	Belongs to the peptidase S41A family
BsBEST3102_19940	COG2226	methyltransferase
BsBEST3102_19960	COG1876	peptidase activity
BsBEST3102_19970	COG0813	purine-nucleoside phosphorylase activity
BsBEST3102_20000	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3102_20040	COG4479	Belongs to the UPF0346 family
BsBEST3102_20060	COG1509	lysine 2,3-aminomutase activity
BsBEST3102_20070	COG0456	acetyltransferase
BsBEST3102_20080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3102_20090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3102_20100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3102_20110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3102_20140	COG0456	acetyltransferase
BsBEST3102_20150	COG0463	Glycosyl transferase, family 2
BsBEST3102_20180	COG4641	Protein conserved in bacteria
BsBEST3102_20190	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BsBEST3102_20200	COG1086	Polysaccharide biosynthesis protein
BsBEST3102_20220	COG3331	DNA recombination
BsBEST3102_20310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3102_20370	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BsBEST3102_20380	COG0756	dUTP diphosphatase activity
BsBEST3102_20390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_20400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3102_20420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3102_20440	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3102_20440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3102_20450	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3102_20450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3102_20460	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3102_20640	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3102_20660	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BsBEST3102_20670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3102_20720	COG3584	3D domain protein
BsBEST3102_20730	COG0587	DNA-directed DNA polymerase activity
BsBEST3102_20740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3102_20750	COG0358	DNA primase activity
BsBEST3102_20760	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3102_20780	COG2887	Belongs to the helicase family. UvrD subfamily
BsBEST3102_20840	COG3420	alginic acid biosynthetic process
BsBEST3102_20840	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3102_20850	COG4195	phage-related replication protein
BsBEST3102_20880	COG2135	peptidase activity
BsBEST3102_20890	COG1793	dna ligase
BsBEST3102_20990	COG4474	Belongs to the UPF0398 family
BsBEST3102_21010	COG1388	LysM domain
BsBEST3102_21050	COG3645	SOS response
BsBEST3102_21050	COG3646	Phage regulatory protein
BsBEST3102_21160	COG3655	Transcriptional regulator
BsBEST3102_21190	COG0582	viral genome integration into host DNA
BsBEST3102_21350	COG3655	Transcriptional regulator
BsBEST3102_21420	COG1395	domain, Protein
BsBEST3102_21460	COG0776	regulation of translation
BsBEST3102_21520	COG4373	Mu-like prophage FluMu protein gp28
BsBEST3102_21720	COG0582	viral genome integration into host DNA
BsBEST3102_21780	COG0739	heme binding
BsBEST3102_21780	COG0741	lytic transglycosylase activity
BsBEST3102_21780	COG1196	nuclear chromosome segregation
BsBEST3102_21800	COG2433	Pfam Transposase IS66
BsBEST3102_21820	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3102_21820	COG4632	Exopolysaccharide biosynthesis protein
BsBEST3102_21850	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_21880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3102_21890	COG0463	Glycosyl transferase, family 2
BsBEST3102_21900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_21910	COG2274	protein secretion by the type I secretion system
BsBEST3102_21910	COG3271	cysteine-type peptidase activity
BsBEST3102_21940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3102_21990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3102_22020	COG5444	nuclease activity
BsBEST3102_22030	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3102_22050	COG1525	nuclease
BsBEST3102_22070	COG2746	aminoglycoside 3-N-acetyltransferase activity
BsBEST3102_22120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3102_22130	COG1086	Polysaccharide biosynthesis protein
BsBEST3102_22140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3102_22150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3102_22160	COG1846	Transcriptional regulator
BsBEST3102_22170	COG0534	Mate efflux family protein
BsBEST3102_22190	COG4698	Protein conserved in bacteria
BsBEST3102_22200	COG2755	lipolytic protein G-D-S-L family
BsBEST3102_22210	COG1999	signal sequence binding
BsBEST3102_22230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BsBEST3102_22240	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3102_22250	COG1272	protein, Hemolysin III
BsBEST3102_22260	COG0204	Acyl-transferase
BsBEST3102_22270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3102_22280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3102_22290	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3102_22310	COG2136	Putative SAM-dependent methyltransferase
BsBEST3102_22310	COG2521	methyltransferase
BsBEST3102_22330	COG0129	dihydroxy-acid dehydratase activity
BsBEST3102_22340	COG1413	lyase activity
BsBEST3102_22350	COG1418	mRNA catabolic process
BsBEST3102_22360	COG0386	Belongs to the glutathione peroxidase family
BsBEST3102_22370	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BsBEST3102_22380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3102_22390	COG1278	Cold shock
BsBEST3102_22430	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3102_22440	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BsBEST3102_22450	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3102_22470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3102_22500	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3102_22510	COG1755	Isoprenylcysteine carboxyl methyltransferase
BsBEST3102_22520	COG3424	synthase
BsBEST3102_22530	COG2233	PERMEase
BsBEST3102_22540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3102_22550	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BsBEST3102_22570	COG0800	Aldolase
BsBEST3102_22580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3102_22590	COG1609	Transcriptional regulator
BsBEST3102_22600	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BsBEST3102_22610	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_22620	COG1199	ATP-dependent helicase activity
BsBEST3102_22640	COG0116	Belongs to the methyltransferase superfamily
BsBEST3102_22660	COG4474	Belongs to the UPF0398 family
BsBEST3102_22670	COG3359	exonuclease
BsBEST3102_22680	COG1111	helicase
BsBEST3102_22680	COG1205	dead DEAH box helicase
BsBEST3102_22690	COG2190	(PTS) system
BsBEST3102_22700	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3102_22760	COG3331	DNA recombination
BsBEST3102_22770	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3102_22770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3102_22790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BsBEST3102_22800	COG3935	DnaD domain protein
BsBEST3102_22810	COG0017	Asparaginyl-tRNA synthetase
BsBEST3102_22820	COG0436	Aminotransferase
BsBEST3102_22830	COG5353	protein conserved in bacteria
BsBEST3102_22850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BsBEST3102_22850	COG1199	ATP-dependent helicase activity
BsBEST3102_22860	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BsBEST3102_22870	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BsBEST3102_22880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BsBEST3102_22890	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BsBEST3102_22890	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BsBEST3102_22900	COG0617	tRNA 3'-terminal CCA addition
BsBEST3102_22910	COG0438	transferase activity, transferring glycosyl groups
BsBEST3102_22920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3102_22930	COG1803	Methylglyoxal synthase
BsBEST3102_22940	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BsBEST3102_22950	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3102_22960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3102_22980	COG4347	Protein of unknown function (DUF1405)
BsBEST3102_22990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3102_22990	COG2010	Cytochrome c
BsBEST3102_23000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3102_23010	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3102_23030	COG5582	Belongs to the UPF0302 family
BsBEST3102_23040	COG0457	Tetratricopeptide repeat
BsBEST3102_23050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BsBEST3102_23060	COG0287	Prephenate dehydrogenase
BsBEST3102_23070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BsBEST3102_23080	COG0159	tryptophan synthase activity
BsBEST3102_23090	COG0133	tryptophan synthase activity
BsBEST3102_23100	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3102_23120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BsBEST3102_23130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3102_23140	COG4401	Chorismate mutase type I
BsBEST3102_23150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BsBEST3102_23160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BsBEST3102_23170	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BsBEST3102_23180	COG0105	UTP biosynthetic process
BsBEST3102_23190	COG0142	geranyltranstransferase activity
BsBEST3102_23200	COG2226	methyltransferase
BsBEST3102_23210	COG0142	geranyltranstransferase activity
BsBEST3102_23230	COG0302	gtp cyclohydrolase
BsBEST3102_23240	COG0776	regulation of translation
BsBEST3102_23250	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3102_23280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BsBEST3102_23290	COG1160	GTP binding
BsBEST3102_23340	COG1304	FMN binding
BsBEST3102_23350	COG0539	negative regulation of cytoplasmic translation
BsBEST3102_23360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BsBEST3102_23380	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BsBEST3102_23390	COG2959	enzyme of heme biosynthesis
BsBEST3102_23400	COG3773	Cell wall hydrolase
BsBEST3102_23400	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_23410	COG2339	peptidase activity
BsBEST3102_23420	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3102_23430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3102_23440	COG4862	establishment of competence for transformation
BsBEST3102_23450	COG1408	metallophosphoesterase
BsBEST3102_23460	COG1388	LysM domain
BsBEST3102_23470	COG1266	CAAX protease self-immunity
BsBEST3102_23480	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3102_23490	COG4955	Helix-turn-helix domain
BsBEST3102_23500	COG1141	Ferredoxin
BsBEST3102_23510	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BsBEST3102_23530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3102_23540	COG0710	3-dehydroquinate dehydratase activity
BsBEST3102_23560	COG1595	DNA-templated transcription, initiation
BsBEST3102_23570	COG5002	protein histidine kinase activity
BsBEST3102_23580	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_23590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3102_23600	COG1333	cytochrome c biogenesis protein
BsBEST3102_23610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_23620	COG1187	pseudouridine synthase activity
BsBEST3102_23630	COG0700	Nucleoside recognition
BsBEST3102_23640	COG2715	membrane protein required for spore maturation
BsBEST3102_23650	COG1686	Belongs to the peptidase S11 family
BsBEST3102_23670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BsBEST3102_23680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BsBEST3102_23690	COG1547	Domain of unknown function (DUF309)
BsBEST3102_23700	COG0456	acetyltransferase
BsBEST3102_23710	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BsBEST3102_23720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3102_23720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3102_23730	COG0307	riboflavin synthase, alpha
BsBEST3102_23740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3102_23740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3102_23760	COG0681	Belongs to the peptidase S26 family
BsBEST3102_23780	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BsBEST3102_23810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BsBEST3102_23820	COG4086	secreted protein
BsBEST3102_23830	COG0019	diaminopimelate decarboxylase activity
BsBEST3102_23840	COG0697	spore germination
BsBEST3102_23870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3102_23910	COG1191	sigma factor activity
BsBEST3102_23920	COG2172	sigma factor antagonist activity
BsBEST3102_23930	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3102_23940	COG1686	Belongs to the peptidase S11 family
BsBEST3102_23950	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BsBEST3102_23960	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BsBEST3102_23970	COG4974	Belongs to the 'phage' integrase family
BsBEST3102_23990	COG0735	belongs to the Fur family
BsBEST3102_24000	COG1300	Membrane
BsBEST3102_24020	COG0281	malic enzyme
BsBEST3102_24030	COG1757	Na H antiporter
BsBEST3102_24040	COG1027	Aspartate ammonia-lyase
BsBEST3102_24050	COG0252	asparaginase activity
BsBEST3102_24060	COG1396	sequence-specific DNA binding
BsBEST3102_24070	COG1379	DNA repair
BsBEST3102_24080	COG0494	nUDIX hydrolase
BsBEST3102_24100	COG0667	Aldo Keto reductase
BsBEST3102_24120	COG1073	alpha beta
BsBEST3102_24140	COG4918	Iron-sulphur cluster biosynthesis
BsBEST3102_24150	COG0456	acetyltransferase
BsBEST3102_24150	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BsBEST3102_24160	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3102_24170	COG0456	acetyltransferase
BsBEST3102_24190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3102_24210	COG2211	Major facilitator Superfamily
BsBEST3102_24230	COG0346	lactoylglutathione lyase activity
BsBEST3102_24240	COG1072	(Pantothenic acid kinase))
BsBEST3102_24250	COG3048	D-serine ammonia-lyase activity
BsBEST3102_24260	COG0300	oxidoreductase activity
BsBEST3102_24270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3102_24280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3102_24290	COG4187	Peptidase family M20/M25/M40
BsBEST3102_24300	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3102_24310	COG0596	Alpha beta hydrolase
BsBEST3102_24320	COG1234	tRNA 3'-trailer cleavage
BsBEST3102_24330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BsBEST3102_24340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3102_24350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3102_24370	COG0706	membrane insertase activity
BsBEST3102_24380	COG3361	conserved protein (COG2071)
BsBEST3102_24390	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3102_24400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3102_24410	COG0346	lactoylglutathione lyase activity
BsBEST3102_24420	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3102_24430	COG4129	membrane
BsBEST3102_24440	COG1126	abc transporter atp-binding protein
BsBEST3102_24450	COG0765	amino acid transport
BsBEST3102_24460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3102_24480	COG1597	lipid kinase activity
BsBEST3102_24490	COG2814	Major facilitator Superfamily
BsBEST3102_24500	COG0789	Transcriptional regulator
BsBEST3102_24500	COG4978	Transcriptional regulator
BsBEST3102_24510	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3102_24520	COG0022	dehydrogenase e1 component
BsBEST3102_24530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3102_24540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3102_24550	COG3426	butyrate kinase activity
BsBEST3102_24560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3102_24570	COG0280	phosphate acetyltransferase
BsBEST3102_24580	COG3290	protein histidine kinase activity
BsBEST3102_24580	COG3829	transcription factor binding
BsBEST3102_24600	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BsBEST3102_24610	COG2079	MmgE PrpD family protein
BsBEST3102_24620	COG0372	Belongs to the citrate synthase family
BsBEST3102_24630	COG1960	acyl-CoA dehydrogenase activity
BsBEST3102_24640	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3102_24650	COG0183	Belongs to the thiolase family
BsBEST3102_24660	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3102_24670	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_24690	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3102_24700	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_24710	COG0750	zinc metalloprotease
BsBEST3102_24720	COG0497	DNA recombination
BsBEST3102_24730	COG1438	arginine binding
BsBEST3102_24740	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BsBEST3102_24750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BsBEST3102_24760	COG0142	geranyltranstransferase activity
BsBEST3102_24770	COG1722	exodeoxyribonuclease VII activity
BsBEST3102_24780	COG1570	exodeoxyribonuclease VII activity
BsBEST3102_24790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BsBEST3102_24800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3102_24810	COG1302	Protein conserved in bacteria
BsBEST3102_24820	COG0439	Biotin carboxylase
BsBEST3102_24830	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3102_24910	COG3854	ATPases associated with a variety of cellular activities
BsBEST3102_24930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BsBEST3102_24940	COG0006	proline dipeptidase activity
BsBEST3102_24950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BsBEST3102_24970	COG3872	metal-dependent enzyme
BsBEST3102_24990	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3102_25000	COG1321	iron dependent repressor
BsBEST3102_25010	COG0095	Lipoate-protein ligase
BsBEST3102_25020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3102_25030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3102_25040	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3102_25050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BsBEST3102_25060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3102_25090	COG1396	sequence-specific DNA binding
BsBEST3102_25110	COG0681	Belongs to the peptidase S26 family
BsBEST3102_25160	COG4940	Competence protein ComGF
BsBEST3102_25180	COG4970	Tfp pilus assembly protein FimT
BsBEST3102_25190	COG4537	Required for transformation and DNA binding
BsBEST3102_25200	COG1459	type II secretion system
BsBEST3102_25210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BsBEST3102_25220	COG0598	Magnesium transport protein CorA
BsBEST3102_25230	COG1253	flavin adenine dinucleotide binding
BsBEST3102_25240	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3102_25250	COG1393	Belongs to the ArsC family
BsBEST3102_25270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3102_25290	COG0011	TIGRFAM Protein of
BsBEST3102_25310	COG2866	Carboxypeptidase
BsBEST3102_25320	COG1368	sulfuric ester hydrolase activity
BsBEST3102_25330	COG1940	carbohydrate kinase activity
BsBEST3102_25340	COG4483	Protein conserved in bacteria
BsBEST3102_25350	COG0457	Tetratricopeptide repeat
BsBEST3102_25350	COG0705	Rhomboid family
BsBEST3102_25370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BsBEST3102_25390	COG0438	transferase activity, transferring glycosyl groups
BsBEST3102_25420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3102_25430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3102_25440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3102_25450	COG0581	inorganic phosphate transmembrane transporter activity
BsBEST3102_25460	COG0573	inorganic phosphate transmembrane transporter activity
BsBEST3102_25470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BsBEST3102_25480	COG0768	penicillin binding
BsBEST3102_25490	COG0477	Major facilitator Superfamily
BsBEST3102_25500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3102_25510	COG2839	Protein conserved in bacteria
BsBEST3102_25520	COG5521	maltodextrose utilization protein MalA
BsBEST3102_25540	COG1388	LysM domain
BsBEST3102_25550	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BsBEST3102_25560	COG4709	membrane
BsBEST3102_25570	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BsBEST3102_25580	COG0735	belongs to the Fur family
BsBEST3102_25590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3102_25610	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BsBEST3102_25620	COG0513	Belongs to the DEAD box helicase family
BsBEST3102_25640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BsBEST3102_25650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BsBEST3102_25660	COG2384	SAM-dependent methyltransferase
BsBEST3102_25670	COG2010	Cytochrome c
BsBEST3102_25680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BsBEST3102_25690	COG0358	DNA primase activity
BsBEST3102_25700	COG1671	Belongs to the UPF0178 family
BsBEST3102_25710	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BsBEST3102_25720	COG0517	IMP dehydrogenase activity
BsBEST3102_25730	COG0751	glycine-tRNA ligase activity
BsBEST3102_25740	COG0752	glycyl-tRNA synthetase alpha subunit
BsBEST3102_25750	COG1381	Involved in DNA repair and RecF pathway recombination
BsBEST3102_25770	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BsBEST3102_25780	COG0295	cytidine deaminase activity
BsBEST3102_25790	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BsBEST3102_25800	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BsBEST3102_25810	COG1480	7TM receptor with intracellular HD hydrolase
BsBEST3102_25820	COG1702	phosphate starvation-inducible protein PhoH
BsBEST3102_25830	COG0561	phosphatase activity
BsBEST3102_25860	COG4864	UPF0365 protein
BsBEST3102_25870	COG1030	water channel activity
BsBEST3102_25880	COG1610	YqeY-like protein
BsBEST3102_25900	COG1283	sodium-dependent phosphate transmembrane transporter activity
BsBEST3102_25910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3102_25920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BsBEST3102_25930	COG2264	protein methyltransferase activity
BsBEST3102_25940	COG0484	heat shock protein binding
BsBEST3102_25950	COG0443	Heat shock 70 kDa protein
BsBEST3102_25960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BsBEST3102_25970	COG1420	regulation of RNA biosynthetic process
BsBEST3102_25980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3102_25990	COG0481	GTPase activity
BsBEST3102_26010	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_26020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BsBEST3102_26040	COG0268	Binds directly to 16S ribosomal RNA
BsBEST3102_26050	COG1466	dna polymerase III delta subunit
BsBEST3102_26070	COG0658	competence protein
BsBEST3102_26070	COG2333	competence protein COMEC
BsBEST3102_26090	COG2131	deaminase
BsBEST3102_26100	COG1596	polysaccharide export
BsBEST3102_26100	COG1555	photosystem II stabilization
BsBEST3102_26110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3102_26120	COG2226	methyltransferase
BsBEST3102_26130	COG0799	negative regulation of ribosome biogenesis
BsBEST3102_26140	COG1713	HD superfamily hydrolase involved in NAD metabolism
BsBEST3102_26150	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BsBEST3102_26160	COG1534	Rna-binding protein
BsBEST3102_26170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BsBEST3102_26180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3102_26190	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BsBEST3102_26200	COG2755	lipolytic protein G-D-S-L family
BsBEST3102_26210	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_26210	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_26220	COG0398	Pfam SNARE associated Golgi protein
BsBEST3102_26230	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BsBEST3102_26250	COG3209	COG3209 Rhs family protein
BsBEST3102_26270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3102_26290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3102_26300	COG0798	PFAM Bile acid sodium symporter
BsBEST3102_26310	COG0346	lactoylglutathione lyase activity
BsBEST3102_26320	COG0640	Transcriptional regulator
BsBEST3102_26330	COG3403	YqcI/YcgG family
BsBEST3102_26340	COG0457	Tetratricopeptide repeat
BsBEST3102_26370	COG5444	nuclease activity
BsBEST3102_26420	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_26420	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_26430	COG4824	toxin secretion phage lysis holin
BsBEST3102_26490	COG3778	Protein conserved in bacteria
BsBEST3102_26500	COG3299	homolog of phage Mu protein gp47
BsBEST3102_26510	COG3628	GPW Gp25 family protein
BsBEST3102_26530	COG4193	domain, Protein
BsBEST3102_26540	COG1652	LysM domain
BsBEST3102_26550	COG3953	SLT domain
BsBEST3102_26550	COG5280	Phage tail tape measure protein TP901
BsBEST3102_26680	COG4653	Phage capsid family
BsBEST3102_26690	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3102_26710	COG2369	cell adhesion
BsBEST3102_26720	COG5518	Phage portal protein
BsBEST3102_26730	COG1783	phage Terminase large subunit
BsBEST3102_26740	COG5484	DNA packaging
BsBEST3102_26760	COG3677	Transposase
BsBEST3102_26790	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BsBEST3102_26810	COG1484	DNA-dependent DNA replication
BsBEST3102_26820	COG3935	DnaD domain protein
BsBEST3102_26830	COG3723	Recombinational DNA repair protein, rece pathway
BsBEST3102_26840	COG5377	YqaJ viral recombinase family
BsBEST3102_26900	COG1476	TRANSCRIPTIONal
BsBEST3102_26910	COG3620	sequence-specific DNA binding
BsBEST3102_26930	COG0563	adenylate kinase activity
BsBEST3102_26940	COG2856	Zn peptidase
BsBEST3102_26960	COG3223	Belongs to the PsiE family
BsBEST3102_26970	COG5002	protein histidine kinase activity
BsBEST3102_26970	COG0642	Histidine kinase
BsBEST3102_26980	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_26990	COG2311	Membrane
BsBEST3102_27000	COG0454	-acetyltransferase
BsBEST3102_27010	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3102_27030	COG0730	response to heat
BsBEST3102_27040	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3102_27050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3102_27050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3102_27060	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3102_27060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3102_27070	COG2210	Belongs to the sulfur carrier protein TusA family
BsBEST3102_27080	COG1937	Protein conserved in bacteria
BsBEST3102_27110	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3102_27130	COG0789	Transcriptional regulator
BsBEST3102_27130	COG4978	Transcriptional regulator
BsBEST3102_27140	COG2814	Major facilitator Superfamily
BsBEST3102_27150	COG0456	acetyltransferase
BsBEST3102_27160	COG1253	flavin adenine dinucleotide binding
BsBEST3102_27180	COG0697	spore germination
BsBEST3102_27190	COG0583	DNA-binding transcription factor activity
BsBEST3102_27200	COG2072	flavoprotein involved in K transport
BsBEST3102_27210	COG1230	cation diffusion facilitator family transporter
BsBEST3102_27220	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3102_27230	COG0583	DNA-binding transcription factor activity
BsBEST3102_27250	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3102_27260	COG1687	branched-chain amino acid
BsBEST3102_27270	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BsBEST3102_27280	COG1522	sequence-specific DNA binding
BsBEST3102_27290	COG2732	(Barnase) inhibitor
BsBEST3102_27300	COG2124	cytochrome p450
BsBEST3102_27330	COG1335	isochorismatase
BsBEST3102_27350	COG2318	DinB family
BsBEST3102_27370	COG2070	2-Nitropropane dioxygenase
BsBEST3102_27400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3102_27430	COG3443	Belongs to the bacterial solute-binding protein 9 family
BsBEST3102_27440	COG1595	DNA-templated transcription, initiation
BsBEST3102_27450	COG0667	Aldo Keto reductase
BsBEST3102_27460	COG2851	Citrate transporter
BsBEST3102_27470	COG0583	DNA-binding transcription factor activity
BsBEST3102_27480	COG2828	Protein conserved in bacteria
BsBEST3102_27500	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_27510	COG5566	PFAM Mor transcription activator
BsBEST3102_27520	COG0596	Alpha beta hydrolase
BsBEST3102_27530	COG4991	sh3 domain protein
BsBEST3102_27540	COG4991	sh3 domain protein
BsBEST3102_27550	COG0346	lactoylglutathione lyase activity
BsBEST3102_27570	COG5577	PFAM Coat F domain
BsBEST3102_27580	COG1063	alcohol dehydrogenase
BsBEST3102_27600	COG5577	PFAM Coat F domain
BsBEST3102_27610	COG0789	Transcriptional regulator
BsBEST3102_27630	COG1064	alcohol dehydrogenase
BsBEST3102_27640	COG0693	protein deglycase activity
BsBEST3102_27650	COG1621	beta-fructofuranosidase activity
BsBEST3102_27670	COG3716	PTS system mannose fructose sorbose family IID component
BsBEST3102_27680	COG3715	PTS system
BsBEST3102_27690	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3102_27700	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3102_27710	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3102_27710	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BsBEST3102_27720	COG1113	amino acid transport
BsBEST3102_27730	COG1280	lysine exporter protein (LysE YggA)
BsBEST3102_27740	COG1378	Sugar-specific transcriptional regulator TrmB
BsBEST3102_27750	COG1595	DNA-templated transcription, initiation
BsBEST3102_27770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BsBEST3102_27770	COG2755	lipolytic protein G-D-S-L family
BsBEST3102_27790	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3102_27790	COG2124	cytochrome p450
BsBEST3102_27800	COG1309	transcriptional regulator
BsBEST3102_27810	COG2226	methyltransferase
BsBEST3102_27830	COG2116	formate transmembrane transporter activity
BsBEST3102_27840	COG5609	conserved protein (DUF2294)
BsBEST3102_27850	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3102_27860	COG2427	Protein of unknown function (DUF1641)
BsBEST3102_27880	COG0626	cystathionine gamma-synthase activity
BsBEST3102_27890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3102_27900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BsBEST3102_27910	COG2226	methyltransferase
BsBEST3102_27940	COG0768	penicillin binding
BsBEST3102_27950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BsBEST3102_27960	COG0572	uridine kinase
BsBEST3102_27970	COG0826	peptidase U32
BsBEST3102_27980	COG0826	peptidase U32
BsBEST3102_27990	COG4122	O-methyltransferase activity
BsBEST3102_28000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3102_28010	COG3906	Belongs to the UPF0473 family
BsBEST3102_28020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BsBEST3102_28030	COG4472	Bacterial protein of unknown function (DUF965)
BsBEST3102_28040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BsBEST3102_28050	COG0628	permease
BsBEST3102_28060	COG1126	abc transporter atp-binding protein
BsBEST3102_28070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3102_28080	COG0765	amino acid transport
BsBEST3102_28090	COG0765	amino acid transport
BsBEST3102_28120	COG3881	PFAM PRC-barrel domain
BsBEST3102_28130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BsBEST3102_28140	COG0457	Tetratricopeptide repeat
BsBEST3102_28150	COG0482	sulfurtransferase activity
BsBEST3102_28160	COG1104	cysteine desulfurase activity
BsBEST3102_28170	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3102_28180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BsBEST3102_28190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BsBEST3102_28200	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BsBEST3102_28210	COG0124	histidyl-tRNA synthetase
BsBEST3102_28230	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_28230	COG3103	Sh3 type 3 domain protein
BsBEST3102_28230	COG4991	sh3 domain protein
BsBEST3102_28240	COG1490	D-aminoacyl-tRNA deacylase activity
BsBEST3102_28250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BsBEST3102_28260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3102_28270	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BsBEST3102_28270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3102_28280	COG5416	Lipopolysaccharide assembly protein A domain
BsBEST3102_28290	COG0490	domain, Protein
BsBEST3102_28300	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3102_28300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3102_28320	COG2244	polysaccharide biosynthetic process
BsBEST3102_28330	COG2323	membrane
BsBEST3102_28350	COG1862	Preprotein translocase
BsBEST3102_28360	COG0343	queuine tRNA-ribosyltransferase activity
BsBEST3102_28370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BsBEST3102_28390	COG2255	four-way junction helicase activity
BsBEST3102_28400	COG0632	four-way junction helicase activity
BsBEST3102_28420	COG2814	Major facilitator Superfamily
BsBEST3102_28430	COG0673	inositol 2-dehydrogenase activity
BsBEST3102_28440	COG2112	serine threonine protein kinase
BsBEST3102_28480	COG1115	amino acid carrier protein
BsBEST3102_28490	COG0217	transcriptional regulatory protein
BsBEST3102_28510	COG1388	LysM domain
BsBEST3102_28520	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BsBEST3102_28530	COG0157	Belongs to the NadC ModD family
BsBEST3102_28540	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BsBEST3102_28550	COG1104	cysteine desulfurase activity
BsBEST3102_28560	COG1827	regulation of RNA biosynthetic process
BsBEST3102_28570	COG0077	Prephenate dehydratase
BsBEST3102_28580	COG4492	Belongs to the UPF0735 family
BsBEST3102_28590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BsBEST3102_28600	COG3290	protein histidine kinase activity
BsBEST3102_28610	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BsBEST3102_28620	COG2868	ribosomal protein
BsBEST3102_28630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BsBEST3102_28640	COG1994	Peptidase M50
BsBEST3102_28650	COG0739	heme binding
BsBEST3102_28660	COG2894	cell division
BsBEST3102_28670	COG0850	regulation of cytokinetic process
BsBEST3102_28680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BsBEST3102_28700	COG1077	Cell shape determining protein MreB Mrl
BsBEST3102_28710	COG2003	Belongs to the UPF0758 family
BsBEST3102_28720	COG0424	maF-like protein
BsBEST3102_28740	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BsBEST3102_28750	COG0285	dihydrofolate synthase activity
BsBEST3102_28760	COG0525	valine-tRNA ligase activity
BsBEST3102_28780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3102_28790	COG1388	LysM domain
BsBEST3102_28800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3102_28810	COG0113	porphobilinogen synthase activity
BsBEST3102_28820	COG1587	Uroporphyrinogen-III synthase
BsBEST3102_28830	COG0181	hydroxymethylbilane synthase activity
BsBEST3102_28840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3102_28850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BsBEST3102_28870	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BsBEST3102_28880	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BsBEST3102_28890	COG0470	DNA polymerase III
BsBEST3102_28890	COG1067	ATP-dependent peptidase activity
BsBEST3102_28900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BsBEST3102_28910	COG0544	peptidyl-prolyl cis-trans isomerase activity
BsBEST3102_28920	COG0457	Tetratricopeptide repeat
BsBEST3102_28920	COG1477	protein flavinylation
BsBEST3102_28930	COG0066	3-isopropylmalate dehydratase activity
BsBEST3102_28940	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BsBEST3102_28950	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3102_28960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3102_28970	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BsBEST3102_28980	COG0440	acetolactate synthase activity
BsBEST3102_28990	COG0028	Belongs to the TPP enzyme family
BsBEST3102_29010	COG0454	-acetyltransferase
BsBEST3102_29020	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BsBEST3102_29030	COG0622	Phosphoesterase
BsBEST3102_29040	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BsBEST3102_29050	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BsBEST3102_29060	COG5401	PFAM Sporulation and spore germination
BsBEST3102_29070	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3102_29080	COG1846	Transcriptional regulator
BsBEST3102_29090	COG2197	response regulator
BsBEST3102_29100	COG0824	Thioesterase
BsBEST3102_29110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BsBEST3102_29120	COG1053	succinate dehydrogenase
BsBEST3102_29130	COG2009	succinate dehydrogenase
BsBEST3102_29140	COG1719	4-vinyl reductase, 4VR
BsBEST3102_29150	COG0527	aspartate kinase activity
BsBEST3102_29160	COG0322	excinuclease ABC activity
BsBEST3102_29170	COG3118	belongs to the thioredoxin family
BsBEST3102_29180	COG3534	alpha-L-arabinofuranosidase
BsBEST3102_29200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BsBEST3102_29210	COG2086	electron transfer activity
BsBEST3102_29220	COG1024	Enoyl-CoA hydratase
BsBEST3102_29230	COG1309	transcriptional regulator
BsBEST3102_29240	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3102_29250	COG3766	membrane
BsBEST3102_29260	COG1193	negative regulation of DNA recombination
BsBEST3102_29270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3102_29270	COG1796	DNA polymerase
BsBEST3102_29280	COG1286	toxin biosynthetic process
BsBEST3102_29290	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BsBEST3102_29300	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3102_29310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3102_29310	COG0072	phenylalanine-tRNA ligase activity
BsBEST3102_29320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BsBEST3102_29330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3102_29350	COG3835	regulator
BsBEST3102_29360	COG0277	FAD linked oxidase domain protein
BsBEST3102_29370	COG0247	lactate metabolic process
BsBEST3102_29380	COG0346	lactoylglutathione lyase activity
BsBEST3102_29400	COG1966	Carbon starvation protein
BsBEST3102_29410	COG3534	alpha-L-arabinofuranosidase
BsBEST3102_29420	COG0395	ABC-type sugar transport system, permease component
BsBEST3102_29430	COG1175	transmembrane transport
BsBEST3102_29440	COG1653	transport
BsBEST3102_29450	COG0371	Dehydrogenase
BsBEST3102_29460	COG0647	UMP catabolic process
BsBEST3102_29470	COG0235	Class ii aldolase
BsBEST3102_29480	COG1069	ribulokinase activity
BsBEST3102_29490	COG2160	L-arabinose isomerase activity
BsBEST3102_29500	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3102_29510	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3102_29520	COG1363	Peptidase, m42
BsBEST3102_29540	COG3326	Membrane
BsBEST3102_29550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BsBEST3102_29560	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BsBEST3102_29570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BsBEST3102_29590	COG1346	cytolysis
BsBEST3102_29600	COG1380	Effector of murein hydrolase LrgA
BsBEST3102_29610	COG3279	Response regulator of the LytR AlgR family
BsBEST3102_29620	COG3275	phosphorelay sensor kinase activity
BsBEST3102_29630	COG1011	Hydrolase
BsBEST3102_29640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3102_29660	COG0398	Pfam SNARE associated Golgi protein
BsBEST3102_29670	COG1484	DNA-dependent DNA replication
BsBEST3102_29680	COG3611	Membrane attachment protein
BsBEST3102_29690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BsBEST3102_29700	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BsBEST3102_29710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3102_29720	COG1733	regulation of RNA biosynthetic process
BsBEST3102_29730	COG2814	Major facilitator Superfamily
BsBEST3102_29740	COG0656	L-ascorbic acid biosynthetic process
BsBEST3102_29750	COG0237	dephospho-CoA kinase activity
BsBEST3102_29760	COG1971	Probably functions as a manganese efflux pump
BsBEST3102_29770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BsBEST3102_29780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3102_29780	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3102_29790	COG5002	protein histidine kinase activity
BsBEST3102_29800	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_29810	COG0039	L-malate dehydrogenase activity
BsBEST3102_29820	COG0538	isocitrate dehydrogenase activity
BsBEST3102_29830	COG0372	Belongs to the citrate synthase family
BsBEST3102_29840	COG2707	UPF0756 membrane protein
BsBEST3102_29850	COG0628	permease
BsBEST3102_29860	COG3030	protein affecting phage T7 exclusion by the F plasmid
BsBEST3102_29870	COG0469	pyruvate kinase activity
BsBEST3102_29880	COG0205	6-phosphofructokinase activity
BsBEST3102_29890	COG0825	malonyl-CoA metabolic process
BsBEST3102_29900	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BsBEST3102_29910	COG0281	malic enzyme
BsBEST3102_29920	COG0587	DNA-directed DNA polymerase activity
BsBEST3102_29960	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BsBEST3102_29980	COG4109	DRTGG domain
BsBEST3102_29990	COG0730	response to heat
BsBEST3102_30000	COG1473	amidohydrolase
BsBEST3102_30010	COG0196	riboflavin kinase activity
BsBEST3102_30020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3102_30030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BsBEST3102_30040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3102_30050	COG1126	abc transporter atp-binding protein
BsBEST3102_30060	COG0765	amino acid transport
BsBEST3102_30070	COG0765	amino acid transport
BsBEST3102_30080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3102_30090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3102_30100	COG0454	-acetyltransferase
BsBEST3102_30110	COG0583	DNA-binding transcription factor activity
BsBEST3102_30120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3102_30130	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_30150	COG0165	Argininosuccinate lyase
BsBEST3102_30160	COG0137	argininosuccinate synthase activity
BsBEST3102_30170	COG0521	Mo-molybdopterin cofactor biosynthetic process
BsBEST3102_30180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BsBEST3102_30190	COG0827	DNA restriction-modification system
BsBEST3102_30200	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BsBEST3102_30210	COG3874	Sporulation protein YtfJ
BsBEST3102_30230	COG1714	RDD family
BsBEST3102_30240	COG0616	signal peptide processing
BsBEST3102_30250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3102_30260	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BsBEST3102_30270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3102_30290	COG0301	tRNA thio-modification
BsBEST3102_30300	COG1104	cysteine desulfurase activity
BsBEST3102_30310	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3102_30320	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BsBEST3102_30330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3102_30340	COG1309	transcriptional regulator
BsBEST3102_30350	COG1956	GAF domain-containing protein
BsBEST3102_30360	COG2199	diguanylate cyclase activity
BsBEST3102_30360	COG2203	Gaf domain
BsBEST3102_30370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BsBEST3102_30390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3102_30400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3102_30410	COG0454	-acetyltransferase
BsBEST3102_30420	COG0517	IMP dehydrogenase activity
BsBEST3102_30430	COG0123	including yeast histone deacetylase and acetoin utilization protein
BsBEST3102_30440	COG1360	Flagellar Motor Protein
BsBEST3102_30450	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3102_30460	COG1609	Transcriptional regulator
BsBEST3102_30470	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BsBEST3102_30470	COG1605	Chorismate mutase
BsBEST3102_30480	COG3118	belongs to the thioredoxin family
BsBEST3102_30490	COG4980	gas vesicle protein
BsBEST3102_30500	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3102_30510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BsBEST3102_30520	COG1674	ftsk spoiiie
BsBEST3102_30530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3102_30540	COG4848	Belongs to the UPF0354 family
BsBEST3102_30550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_30570	COG1363	Peptidase, m42
BsBEST3102_30580	COG5584	Small secreted protein
BsBEST3102_30590	COG0281	malic enzyme
BsBEST3102_30600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3102_30610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BsBEST3102_30630	COG0510	thiamine kinase activity
BsBEST3102_30640	COG1523	belongs to the glycosyl hydrolase 13 family
BsBEST3102_30650	COG1597	lipid kinase activity
BsBEST3102_30670	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3102_30680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3102_30690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3102_30700	COG2252	PERMEase
BsBEST3102_30710	COG4473	ABC transporter
BsBEST3102_30720	COG1131	(ABC) transporter
BsBEST3102_30740	COG1349	DNA-binding transcription factor activity
BsBEST3102_30750	COG1187	pseudouridine synthase activity
BsBEST3102_30760	COG2244	polysaccharide biosynthetic process
BsBEST3102_30770	COG2081	HI0933 family
BsBEST3102_30780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BsBEST3102_30800	COG5578	integral membrane protein
BsBEST3102_30810	COG0673	inositol 2-dehydrogenase activity
BsBEST3102_30820	COG1653	transport
BsBEST3102_30830	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3102_30840	COG4209	transmembrane transport
BsBEST3102_30850	COG2207	Transcriptional regulator
BsBEST3102_30860	COG2207	Transcriptional regulator
BsBEST3102_30870	COG1653	transport
BsBEST3102_30880	COG0395	ABC-type sugar transport system, permease component
BsBEST3102_30890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3102_30900	COG2124	cytochrome p450
BsBEST3102_30910	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BsBEST3102_30920	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BsBEST3102_30930	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3102_30940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3102_30950	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BsBEST3102_30960	COG1073	alpha beta
BsBEST3102_30970	COG1609	Transcriptional regulator
BsBEST3102_30980	COG1653	transport
BsBEST3102_30990	COG1175	transmembrane transport
BsBEST3102_31000	COG0395	ABC-type sugar transport system, permease component
BsBEST3102_31010	COG1486	melibiose metabolic process
BsBEST3102_31020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3102_31030	COG0495	leucyl-tRNA aminoacylation
BsBEST3102_31050	COG2202	Pas domain
BsBEST3102_31050	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3102_31060	COG2814	Major facilitator Superfamily
BsBEST3102_31070	COG2433	Pfam Transposase IS66
BsBEST3102_31080	COG0577	efflux transmembrane transporter activity
BsBEST3102_31090	COG1136	(ABC) transporter
BsBEST3102_31100	COG2205	protein histidine kinase activity
BsBEST3102_31110	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_31120	COG0577	efflux transmembrane transporter activity
BsBEST3102_31130	COG1136	(ABC) transporter
BsBEST3102_31160	COG1131	(ABC) transporter
BsBEST3102_31170	COG1725	Transcriptional regulator
BsBEST3102_31190	COG1242	4 iron, 4 sulfur cluster binding
BsBEST3102_31200	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BsBEST3102_31220	COG2267	carboxylic ester hydrolase activity
BsBEST3102_31230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BsBEST3102_31240	COG1113	amino acid transport
BsBEST3102_31250	COG0367	asparagine synthase
BsBEST3102_31260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BsBEST3102_31270	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BsBEST3102_31290	COG1506	peptidase
BsBEST3102_31300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3102_31310	COG1116	anion transmembrane transporter activity
BsBEST3102_31320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3102_31330	COG0494	nUDIX hydrolase
BsBEST3102_31340	COG4824	toxin secretion phage lysis holin
BsBEST3102_31350	COG0783	Belongs to the Dps family
BsBEST3102_31390	COG1854	S-ribosylhomocysteine lyase activity
BsBEST3102_31400	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BsBEST3102_31410	COG0288	reversible hydration of carbon dioxide
BsBEST3102_31420	COG0254	rRNA binding
BsBEST3102_31430	COG1271	oxidase subunit
BsBEST3102_31440	COG1294	oxidase, subunit
BsBEST3102_31460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3102_31470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3102_31470	COG1321	iron dependent repressor
BsBEST3102_31480	COG1121	(ABC) transporter
BsBEST3102_31490	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3102_31500	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3102_31510	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3102_31520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BsBEST3102_31530	COG0596	Alpha beta hydrolase
BsBEST3102_31540	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BsBEST3102_31550	COG1169	isochorismate synthase
BsBEST3102_31560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3102_31570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3102_31580	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3102_31590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3102_31600	COG0438	transferase activity, transferring glycosyl groups
BsBEST3102_31620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3102_31630	COG0438	transferase activity, transferring glycosyl groups
BsBEST3102_31640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3102_31650	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BsBEST3102_31660	COG0058	SHG alpha-glucan phosphorylase activity
BsBEST3102_31670	COG0297	glycogen (starch) synthase activity
BsBEST3102_31680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3102_31690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3102_31700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BsBEST3102_31710	COG3859	Proton-coupled thiamine transporter YuaJ
BsBEST3102_31720	COG1247	-acetyltransferase
BsBEST3102_31730	COG2268	Band 7 protein
BsBEST3102_31740	COG1585	Membrane protein implicated in regulation of membrane protease activity
BsBEST3102_31750	COG2318	DinB family
BsBEST3102_31770	COG1454	alcohol dehydrogenase
BsBEST3102_31780	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_31790	COG1510	regulation of RNA biosynthetic process
BsBEST3102_31810	COG0569	domain protein
BsBEST3102_31820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3102_31830	COG4682	membrane
BsBEST3102_31840	COG1705	Flagellar rod assembly protein muramidase FlgJ
BsBEST3102_31850	COG0477	Major facilitator Superfamily
BsBEST3102_31860	COG5553	Cysteine dioxygenase type I
BsBEST3102_31870	COG1968	undecaprenyl-diphosphatase activity
BsBEST3102_31880	COG0628	permease
BsBEST3102_31890	COG0673	inositol 2-dehydrogenase activity
BsBEST3102_31900	COG4806	L-rhamnose isomerase
BsBEST3102_31910	COG3254	rhamnose metabolic process
BsBEST3102_31920	COG1070	Carbohydrate kinase
BsBEST3102_31930	COG1349	DNA-binding transcription factor activity
BsBEST3102_31940	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_31940	COG3347	Dehydrogenase
BsBEST3102_31950	COG0840	transmembrane signaling receptor activity
BsBEST3102_31960	COG0840	transmembrane signaling receptor activity
BsBEST3102_31980	COG0840	transmembrane signaling receptor activity
BsBEST3102_31990	COG0840	transmembrane signaling receptor activity
BsBEST3102_32020	COG0432	Pfam Uncharacterised protein family UPF0047
BsBEST3102_32040	COG0366	Alpha amylase catalytic
BsBEST3102_32050	COG1253	flavin adenine dinucleotide binding
BsBEST3102_32060	COG2738	Putative neutral zinc metallopeptidase
BsBEST3102_32090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BsBEST3102_32120	COG0166	Belongs to the GPI family
BsBEST3102_32130	COG1979	alcohol dehydrogenase
BsBEST3102_32140	COG1979	alcohol dehydrogenase
BsBEST3102_32150	COG2155	Conserved Protein
BsBEST3102_32160	COG1098	S1 RNA binding domain
BsBEST3102_32170	COG0436	Aminotransferase
BsBEST3102_32180	COG1522	sequence-specific DNA binding
BsBEST3102_32190	COG2267	carboxylic ester hydrolase activity
BsBEST3102_32210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BsBEST3102_32220	COG2205	protein histidine kinase activity
BsBEST3102_32240	COG5018	Exonuclease
BsBEST3102_32260	COG2814	Major facilitator Superfamily
BsBEST3102_32270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3102_32280	COG3011	Protein conserved in bacteria
BsBEST3102_32300	COG3290	protein histidine kinase activity
BsBEST3102_32310	COG4565	transcriptional regulatory protein
BsBEST3102_32320	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3102_32330	COG3845	ABC transporter
BsBEST3102_32340	COG4603	Belongs to the binding-protein-dependent transport system permease family
BsBEST3102_32350	COG1079	Belongs to the binding-protein-dependent transport system permease family
BsBEST3102_32360	COG3493	citrate carrier protein
BsBEST3102_32380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3102_32380	COG2111	Na H antiporter
BsBEST3102_32390	COG2111	Na H antiporter
BsBEST3102_32400	COG1006	Multisubunit Na H antiporter MnhC subunit
BsBEST3102_32410	COG0651	ATP synthesis coupled electron transport
BsBEST3102_32420	COG1863	multisubunit Na H antiporter MnhE subunit
BsBEST3102_32430	COG2212	antiporter activity
BsBEST3102_32440	COG1320	monovalent cation:proton antiporter activity
BsBEST3102_32450	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3102_32460	COG2197	response regulator
BsBEST3102_32470	COG4585	Histidine kinase
BsBEST3102_32500	COG0142	geranyltranstransferase activity
BsBEST3102_32530	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BsBEST3102_32540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BsBEST3102_32550	COG1335	isochorismatase
BsBEST3102_32560	COG5506	Protein of unknown function (DUF1694)
BsBEST3102_32590	COG0628	permease
BsBEST3102_32620	COG1418	mRNA catabolic process
BsBEST3102_32630	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_32650	COG1511	domain protein
BsBEST3102_32660	COG0433	COG0433 Predicted ATPase
BsBEST3102_32660	COG1674	ftsk spoiiie
BsBEST3102_32670	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3102_32680	COG5417	Belongs to the EsaB family
BsBEST3102_32690	COG4842	Belongs to the WXG100 family
BsBEST3102_32700	COG2508	Transcriptional regulator
BsBEST3102_32700	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3102_32710	COG0686	Belongs to the AlaDH PNT family
BsBEST3102_32720	COG5634	Uncharacterized conserved protein (DUF2278)
BsBEST3102_32730	COG3251	PFAM MbtH domain protein
BsBEST3102_32740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_32750	COG1535	isochorismatase
BsBEST3102_32750	COG3433	isochorismatase activity
BsBEST3102_32760	COG1021	2,3-dihydroxybenzoate-AMP ligase
BsBEST3102_32770	COG1169	isochorismate synthase
BsBEST3102_32780	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_32790	COG2819	hydrolase of the alpha beta superfamily
BsBEST3102_32800	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3102_32810	COG1268	BioY protein
BsBEST3102_32820	COG2056	Na+-H+ antiporter family
BsBEST3102_32830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BsBEST3102_32840	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BsBEST3102_32850	COG3584	3D domain protein
BsBEST3102_32870	COG1252	NADH dehydrogenase
BsBEST3102_32880	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3102_32900	COG0516	GMP reductase activity
BsBEST3102_32910	COG2808	Putative FMN-binding domain
BsBEST3102_32920	COG0456	acetyltransferase
BsBEST3102_32930	COG0316	Belongs to the HesB IscA family
BsBEST3102_32940	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BsBEST3102_32950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3102_32960	COG4844	belongs to the
BsBEST3102_32970	COG1252	NADH dehydrogenase
BsBEST3102_32980	COG4837	Protein of unknown function (DUF1462)
BsBEST3102_32990	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BsBEST3102_33000	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3102_33000	COG1506	peptidase
BsBEST3102_33000	COG4946	Tricorn protease homolog
BsBEST3102_33010	COG0083	homoserine kinase activity
BsBEST3102_33020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BsBEST3102_33030	COG0460	homoserine dehydrogenase
BsBEST3102_33040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3102_33050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3102_33060	COG0647	UMP catabolic process
BsBEST3102_33070	COG2445	Protein of unknown function DUF86
BsBEST3102_33080	COG4470	Protein conserved in bacteria
BsBEST3102_33100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BsBEST3102_33110	COG0739	heme binding
BsBEST3102_33130	COG3377	Domain of unknown function (DUF1805)
BsBEST3102_33140	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3102_33150	COG0730	response to heat
BsBEST3102_33160	COG1801	Protein of unknown function DUF72
BsBEST3102_33180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3102_33190	COG2508	Transcriptional regulator
BsBEST3102_33200	COG2233	PERMEase
BsBEST3102_33210	COG2233	PERMEase
BsBEST3102_33220	COG3648	Uricase
BsBEST3102_33220	COG3195	allantoin biosynthetic process
BsBEST3102_33230	COG2351	hydroxyisourate hydrolase activity
BsBEST3102_33250	COG2080	2 iron, 2 sulfur cluster binding
BsBEST3102_33260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BsBEST3102_33270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BsBEST3102_33280	COG2068	MobA-Related Protein
BsBEST3102_33290	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BsBEST3102_33300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BsBEST3102_33310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3102_33320	COG2356	endonuclease I
BsBEST3102_33330	COG3842	ATPase activity
BsBEST3102_33340	COG2188	Transcriptional regulator
BsBEST3102_33350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3102_33360	COG0395	ABC-type sugar transport system, permease component
BsBEST3102_33370	COG1175	transmembrane transport
BsBEST3102_33380	COG1653	transport
BsBEST3102_33390	COG2222	sugar isomerase
BsBEST3102_33400	COG0322	excinuclease ABC activity
BsBEST3102_33410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3102_33440	COG0346	lactoylglutathione lyase activity
BsBEST3102_33450	COG0640	Transcriptional regulator
BsBEST3102_33460	COG0719	Fe-S assembly protein
BsBEST3102_33470	COG0822	iron-sulfur transferase activity
BsBEST3102_33480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3102_33490	COG0719	Fe-S assembly protein
BsBEST3102_33500	COG0396	ATPase activity
BsBEST3102_33520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3102_33530	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3102_33540	COG2011	ABC-type metal ion transport system permease component
BsBEST3102_33550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BsBEST3102_33570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3102_33580	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3102_33600	COG0509	glycine decarboxylation via glycine cleavage system
BsBEST3102_33610	COG1393	Belongs to the ArsC family
BsBEST3102_33620	COG1960	acyl-CoA dehydrogenase activity
BsBEST3102_33630	COG0183	Belongs to the thiolase family
BsBEST3102_33640	COG1024	Enoyl-CoA hydratase
BsBEST3102_33640	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3102_33660	COG0506	proline dehydrogenase activity
BsBEST3102_33680	COG5577	PFAM Coat F domain
BsBEST3102_33690	COG1846	Transcriptional regulator
BsBEST3102_33700	COG0477	Major facilitator Superfamily
BsBEST3102_33710	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3102_33720	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_33730	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_33740	COG0583	DNA-binding transcription factor activity
BsBEST3102_33760	COG1120	ATPase activity
BsBEST3102_33800	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_33810	COG0783	Belongs to the Dps family
BsBEST3102_33820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3102_33830	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_33840	COG2205	protein histidine kinase activity
BsBEST3102_33840	COG2770	Histidine kinase
BsBEST3102_33860	COG1309	transcriptional regulator
BsBEST3102_33870	COG0114	fumarate hydratase activity
BsBEST3102_33890	COG0697	spore germination
BsBEST3102_33900	COG0814	amino acid
BsBEST3102_33930	COG2197	response regulator
BsBEST3102_33940	COG4585	Histidine kinase
BsBEST3102_33950	COG4758	membrane
BsBEST3102_33960	COG3595	metallopeptidase activity
BsBEST3102_33970	COG1842	Phage shock protein A
BsBEST3102_33980	COG4758	membrane
BsBEST3102_33990	COG2814	Major facilitator Superfamily
BsBEST3102_34000	COG2096	Adenosyltransferase
BsBEST3102_34010	COG1120	ATPase activity
BsBEST3102_34020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3102_34030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3102_34040	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_34050	COG3386	PFAM SMP-30 Gluconolaconase
BsBEST3102_34060	COG2205	protein histidine kinase activity
BsBEST3102_34070	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_34090	COG1191	sigma factor activity
BsBEST3102_34110	COG2140	Oxalate decarboxylase
BsBEST3102_34130	COG0577	efflux transmembrane transporter activity
BsBEST3102_34140	COG1136	(ABC) transporter
BsBEST3102_34150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3102_34160	COG1120	ATPase activity
BsBEST3102_34170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3102_34180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3102_34190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3102_34200	COG0531	amino acid
BsBEST3102_34220	COG1988	membrane-bound metal-dependent
BsBEST3102_34230	COG1368	sulfuric ester hydrolase activity
BsBEST3102_34240	COG1910	domain protein
BsBEST3102_34250	COG0725	ABC transporter, periplasmic molybdate-binding protein
BsBEST3102_34260	COG4149	molybdate abc transporter
BsBEST3102_34270	COG0656	L-ascorbic acid biosynthetic process
BsBEST3102_34290	COG0025	NhaP-type Na H and K H
BsBEST3102_34300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3102_34310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3102_34320	COG3973	AAA domain
BsBEST3102_34330	COG2860	membrane
BsBEST3102_34340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3102_34350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BsBEST3102_34360	COG2217	Heavy metal translocating P-type atpase
BsBEST3102_34370	COG2217	Heavy metal translocating P-type atpase
BsBEST3102_34380	COG2608	mercury ion transmembrane transporter activity
BsBEST3102_34390	COG1937	Protein conserved in bacteria
BsBEST3102_34400	COG0673	inositol 2-dehydrogenase activity
BsBEST3102_34410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3102_34420	COG1289	transmembrane transporter activity
BsBEST3102_34440	COG2076	Multidrug Resistance protein
BsBEST3102_34450	COG1309	transcriptional regulator
BsBEST3102_34460	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_34470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BsBEST3102_34480	COG0557	exoribonuclease II activity
BsBEST3102_34490	COG1647	Serine aminopeptidase, S33
BsBEST3102_34500	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3102_34510	COG0596	Alpha beta hydrolase
BsBEST3102_34520	COG1476	TRANSCRIPTIONal
BsBEST3102_34530	COG1396	sequence-specific DNA binding
BsBEST3102_34540	COG1396	sequence-specific DNA binding
BsBEST3102_34550	COG1733	regulation of RNA biosynthetic process
BsBEST3102_34560	COG0840	transmembrane signaling receptor activity
BsBEST3102_34570	COG1174	glycine betaine transport
BsBEST3102_34580	COG1732	Glycine betaine
BsBEST3102_34590	COG1174	glycine betaine transport
BsBEST3102_34600	COG0517	IMP dehydrogenase activity
BsBEST3102_34600	COG1125	glycine betaine transport
BsBEST3102_34610	COG1510	regulation of RNA biosynthetic process
BsBEST3102_34650	COG5658	integral membrane protein
BsBEST3102_34660	COG0640	Transcriptional regulator
BsBEST3102_34670	COG1174	glycine betaine transport
BsBEST3102_34680	COG1732	Glycine betaine
BsBEST3102_34690	COG1174	glycine betaine transport
BsBEST3102_34700	COG0517	IMP dehydrogenase activity
BsBEST3102_34700	COG1125	glycine betaine transport
BsBEST3102_34710	COG1510	regulation of RNA biosynthetic process
BsBEST3102_34720	COG2095	MarC family integral membrane protein
BsBEST3102_34740	COG3064	Membrane
BsBEST3102_34750	COG4640	response to antibiotic
BsBEST3102_34760	COG0456	acetyltransferase
BsBEST3102_34770	COG0148	phosphopyruvate hydratase activity
BsBEST3102_34780	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BsBEST3102_34790	COG0149	triose-phosphate isomerase activity
BsBEST3102_34800	COG0126	phosphoglycerate kinase activity
BsBEST3102_34810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3102_34820	COG2390	Transcriptional regulator
BsBEST3102_34830	COG2814	Major facilitator Superfamily
BsBEST3102_34840	COG1609	Transcriptional regulator
BsBEST3102_34850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3102_34860	COG0583	DNA-binding transcription factor activity
BsBEST3102_34870	COG0697	spore germination
BsBEST3102_34880	COG1113	amino acid transport
BsBEST3102_34890	COG3858	chitin binding
BsBEST3102_34900	COG1556	Lactate utilization protein
BsBEST3102_34910	COG1139	Iron-sulfur cluster binding protein
BsBEST3102_34920	COG0247	lactate metabolic process
BsBEST3102_34930	COG2197	response regulator
BsBEST3102_34940	COG4585	Histidine kinase
BsBEST3102_34950	COG0842	Transport permease protein
BsBEST3102_34960	COG1131	(ABC) transporter
BsBEST3102_34970	COG0596	Alpha beta hydrolase
BsBEST3102_34980	COG2208	phosphoserine phosphatase activity
BsBEST3102_34990	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BsBEST3102_35000	COG1874	Beta-galactosidase
BsBEST3102_35010	COG3833	ABC-type maltose transport systems, permease component
BsBEST3102_35020	COG1175	transmembrane transport
BsBEST3102_35030	COG2182	Extracellular solute-binding protein
BsBEST3102_35040	COG1609	Transcriptional regulator
BsBEST3102_35050	COG2186	Transcriptional regulator
BsBEST3102_35060	COG1620	l-lactate permease
BsBEST3102_35070	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BsBEST3102_35090	COG5039	Polysaccharide pyruvyl transferase
BsBEST3102_35100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3102_35110	COG0110	maltose O-acetyltransferase activity
BsBEST3102_35120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BsBEST3102_35130	COG2244	polysaccharide biosynthetic process
BsBEST3102_35140	COG1216	Glycosyl transferase, family 2
BsBEST3102_35150	COG5039	Polysaccharide pyruvyl transferase
BsBEST3102_35160	COG1216	Glycosyl transferase, family 2
BsBEST3102_35180	COG0438	transferase activity, transferring glycosyl groups
BsBEST3102_35190	COG1215	transferase activity, transferring glycosyl groups
BsBEST3102_35200	COG0438	transferase activity, transferring glycosyl groups
BsBEST3102_35210	COG1086	Polysaccharide biosynthesis protein
BsBEST3102_35220	COG0489	protein tyrosine kinase activity
BsBEST3102_35230	COG3944	biosynthesis protein
BsBEST3102_35240	COG1396	sequence-specific DNA binding
BsBEST3102_35250	COG2272	Belongs to the type-B carboxylesterase lipase family
BsBEST3102_35270	COG3479	Phenolic acid decarboxylase
BsBEST3102_35300	COG1794	racemase activity, acting on amino acids and derivatives
BsBEST3102_35310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3102_35320	COG1621	beta-fructofuranosidase activity
BsBEST3102_35330	COG1621	beta-fructofuranosidase activity
BsBEST3102_35340	COG0531	amino acid
BsBEST3102_35350	COG1309	transcriptional regulator
BsBEST3102_35360	COG2076	Multidrug Resistance protein
BsBEST3102_35370	COG2076	Multidrug Resistance protein
BsBEST3102_35390	COG0277	FAD linked oxidase domain protein
BsBEST3102_35400	COG3621	Patatin-like phospholipase
BsBEST3102_35410	COG0740	serine-type endopeptidase activity
BsBEST3102_35420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3102_35430	COG0366	Alpha amylase catalytic
BsBEST3102_35440	COG1554	hydrolase, family 65, central catalytic
BsBEST3102_35450	COG5521	maltodextrose utilization protein MalA
BsBEST3102_35460	COG3833	ABC-type maltose transport systems, permease component
BsBEST3102_35470	COG1175	transmembrane transport
BsBEST3102_35480	COG2182	Extracellular solute-binding protein
BsBEST3102_35500	COG1609	Transcriptional regulator
BsBEST3102_35510	COG1611	Belongs to the LOG family
BsBEST3102_35520	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3102_35530	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3102_35540	COG0288	reversible hydration of carbon dioxide
BsBEST3102_35550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3102_35560	COG0577	efflux transmembrane transporter activity
BsBEST3102_35570	COG1136	(ABC) transporter
BsBEST3102_35580	COG5002	protein histidine kinase activity
BsBEST3102_35590	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_35610	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BsBEST3102_35620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3102_35630	COG1481	regulation of sporulation
BsBEST3102_35640	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BsBEST3102_35650	COG1660	Displays ATPase and GTPase activities
BsBEST3102_35660	COG1051	belongs to the nudix hydrolase family
BsBEST3102_35670	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3102_35680	COG0791	NLP P60 protein
BsBEST3102_35680	COG3883	PFAM NLP P60 protein
BsBEST3102_35690	COG0457	Tetratricopeptide repeat
BsBEST3102_35700	COG1132	(ABC) transporter
BsBEST3102_35740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BsBEST3102_35740	COG0140	phosphoribosyl-ATP diphosphatase activity
BsBEST3102_35750	COG0107	imidazoleglycerol-phosphate synthase activity
BsBEST3102_35760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BsBEST3102_35770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BsBEST3102_35780	COG0131	Imidazoleglycerol-phosphate dehydratase
BsBEST3102_35790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BsBEST3102_35800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BsBEST3102_35810	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BsBEST3102_35820	COG4990	cell redox homeostasis
BsBEST3102_35830	COG5297	Belongs to the glycosyl hydrolase family 6
BsBEST3102_35840	COG0110	maltose O-acetyltransferase activity
BsBEST3102_35850	COG0546	phosphoglycolate phosphatase activity
BsBEST3102_35860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BsBEST3102_35870	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BsBEST3102_35880	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BsBEST3102_35890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BsBEST3102_35900	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3102_35910	COG2188	Transcriptional regulator
BsBEST3102_35920	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3102_35930	COG1846	Transcriptional regulator
BsBEST3102_35940	COG2124	cytochrome p450
BsBEST3102_35960	COG1846	Transcriptional regulator
BsBEST3102_35970	COG2814	Major facilitator Superfamily
BsBEST3102_35980	COG1950	PFAM Membrane protein of
BsBEST3102_35990	COG1983	PspC domain protein
BsBEST3102_36000	COG3595	metallopeptidase activity
BsBEST3102_36030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3102_36040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BsBEST3102_36050	COG0556	nucleotide-excision repair
BsBEST3102_36060	COG4897	Protein conserved in bacteria
BsBEST3102_36070	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3102_36070	COG3848	Pyruvate phosphate dikinase
BsBEST3102_36080	COG1309	transcriptional regulator
BsBEST3102_36090	COG2814	Major facilitator Superfamily
BsBEST3102_36100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3102_36120	COG0793	Belongs to the peptidase S41A family
BsBEST3102_36120	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3102_36130	COG2177	Part of the ABC transporter FtsEX involved in
BsBEST3102_36140	COG2884	Cell division ATP-binding protein ftsE
BsBEST3102_36150	COG2010	Cytochrome c
BsBEST3102_36160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3102_36170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BsBEST3102_36180	COG0653	protein targeting
BsBEST3102_36190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BsBEST3102_36210	COG1516	flagellar protein fliS
BsBEST3102_36220	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BsBEST3102_36230	COG1334	flagellar protein FlaG
BsBEST3102_36240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3102_36250	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BsBEST3102_36260	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BsBEST3102_36280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3102_36290	COG1256	bacterial-type flagellum assembly
BsBEST3102_36290	COG4786	Flagellar basal body rod
BsBEST3102_36300	COG3418	PFAM FlgN family protein
BsBEST3102_36310	COG2747	anti-sigma28 factor FlgM
BsBEST3102_36330	COG1040	competence protein
BsBEST3102_36350	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BsBEST3102_36360	COG1307	EDD domain protein, DegV family
BsBEST3102_36370	COG2197	response regulator
BsBEST3102_36380	COG4585	Histidine kinase
BsBEST3102_36390	COG1739	Uncharacterized protein family UPF0029
BsBEST3102_36400	COG1316	TRANSCRIPTIONal
BsBEST3102_36410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3102_36420	COG0438	transferase activity, transferring glycosyl groups
BsBEST3102_36430	COG1215	transferase activity, transferring glycosyl groups
BsBEST3102_36440	COG3206	protein involved in exopolysaccharide biosynthesis
BsBEST3102_36450	COG3307	-O-antigen
BsBEST3102_36460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3102_36470	COG0297	glycogen (starch) synthase activity
BsBEST3102_36470	COG0438	transferase activity, transferring glycosyl groups
BsBEST3102_36480	COG2244	polysaccharide biosynthetic process
BsBEST3102_36510	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3102_36510	COG2247	cell wall binding repeat
BsBEST3102_36520	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3102_36520	COG2247	cell wall binding repeat
BsBEST3102_36540	COG1316	TRANSCRIPTIONal
BsBEST3102_36550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BsBEST3102_36560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3102_36570	COG1215	transferase activity, transferring glycosyl groups
BsBEST3102_36570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3102_36580	COG0463	Glycosyl transferase, family 2
BsBEST3102_36600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3102_36610	COG1134	teichoic acid transport
BsBEST3102_36620	COG1682	transport, permease protein
BsBEST3102_36630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3102_36640	COG0438	transferase activity, transferring glycosyl groups
BsBEST3102_36650	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BsBEST3102_36660	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BsBEST3102_36670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3102_36690	COG4193	domain, Protein
BsBEST3102_36700	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3102_36710	COG0697	spore germination
BsBEST3102_36720	COG0814	amino acid
BsBEST3102_36740	COG2814	Major facilitator Superfamily
BsBEST3102_36750	COG1316	TRANSCRIPTIONal
BsBEST3102_36760	COG0561	phosphatase activity
BsBEST3102_36770	COG0791	NLP P60 protein
BsBEST3102_36790	COG2843	Capsule synthesis protein
BsBEST3102_36810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3102_36820	COG1609	Transcriptional regulator
BsBEST3102_36830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3102_36840	COG1869	D-ribose catabolic process
BsBEST3102_36850	COG1129	ABC transporter
BsBEST3102_36860	COG1172	Belongs to the binding-protein-dependent transport system permease family
BsBEST3102_36870	COG1879	ABC-type sugar transport system periplasmic component
BsBEST3102_36880	COG3103	Sh3 type 3 domain protein
BsBEST3102_36900	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3102_36910	COG3527	Alpha-acetolactate decarboxylase
BsBEST3102_36920	COG0028	Belongs to the TPP enzyme family
BsBEST3102_36930	COG0583	DNA-binding transcription factor activity
BsBEST3102_36940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3102_36970	COG5337	Spore coat protein CotH
BsBEST3102_36990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3102_37010	COG0405	Gamma-glutamyltransferase
BsBEST3102_37020	COG1522	sequence-specific DNA binding
BsBEST3102_37030	COG2059	Chromate
BsBEST3102_37040	COG2059	Chromate
BsBEST3102_37060	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3102_37070	COG0583	DNA-binding transcription factor activity
BsBEST3102_37080	COG1515	deoxyribonuclease V activity
BsBEST3102_37090	COG2849	repeat protein
BsBEST3102_37100	COG5444	nuclease activity
BsBEST3102_37130	COG3878	Protein conserved in bacteria
BsBEST3102_37140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3102_37150	COG4464	protein tyrosine phosphatase activity
BsBEST3102_37160	COG0489	protein tyrosine kinase activity
BsBEST3102_37170	COG3944	biosynthesis protein
BsBEST3102_37190	COG4715	Zinc finger, swim domain protein
BsBEST3102_37200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3102_37210	COG0561	phosphatase activity
BsBEST3102_37220	COG1349	DNA-binding transcription factor activity
BsBEST3102_37230	COG0629	single-stranded DNA binding
BsBEST3102_37270	COG3764	Sortase (surface protein transpeptidase)
BsBEST3102_37290	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_37290	COG2972	Histidine kinase
BsBEST3102_37300	COG1970	mechanosensitive ion channel activity
BsBEST3102_37310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3102_37320	COG0457	Tetratricopeptide repeat
BsBEST3102_37330	COG4786	Flagellar basal body rod
BsBEST3102_37340	COG4786	Flagellar basal body rod
BsBEST3102_37350	COG1077	Cell shape determining protein MreB Mrl
BsBEST3102_37360	COG1609	Transcriptional regulator
BsBEST3102_37370	COG1846	Transcriptional regulator
BsBEST3102_37380	COG2814	Major facilitator Superfamily
BsBEST3102_37390	COG3420	alginic acid biosynthetic process
BsBEST3102_37400	COG1953	Uracil, thiamine, allantoin
BsBEST3102_37410	COG0477	Major facilitator Superfamily
BsBEST3102_37420	COG1335	isochorismatase
BsBEST3102_37440	COG0004	ammonium transporteR
BsBEST3102_37450	COG0347	Belongs to the P(II) protein family
BsBEST3102_37460	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3102_37480	COG0739	heme binding
BsBEST3102_37490	COG1247	-acetyltransferase
BsBEST3102_37510	COG2089	acid synthase
BsBEST3102_37530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3102_37540	COG0789	Transcriptional regulator
BsBEST3102_37560	COG2910	NAD(P)H-binding
BsBEST3102_37570	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3102_37580	COG0804	urea catabolic process
BsBEST3102_37590	COG0832	Belongs to the urease beta subunit family
BsBEST3102_37600	COG0831	urea catabolic process
BsBEST3102_37620	COG3237	CsbD-like
BsBEST3102_37630	COG1994	Peptidase M50
BsBEST3102_37640	COG0457	Tetratricopeptide repeat
BsBEST3102_37650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BsBEST3102_37660	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BsBEST3102_37680	COG2304	oxidoreductase activity
BsBEST3102_37690	COG2304	oxidoreductase activity
BsBEST3102_37710	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3102_37720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3102_37740	COG4836	Membrane
BsBEST3102_37760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BsBEST3102_37770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BsBEST3102_37780	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BsBEST3102_37790	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BsBEST3102_37800	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BsBEST3102_37810	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BsBEST3102_37830	COG0356	it plays a direct role in the translocation of protons across the membrane
BsBEST3102_37850	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BsBEST3102_37860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BsBEST3102_37870	COG4475	Protein of unknown function (DUF436)
BsBEST3102_37880	COG0698	ribose 5-phosphate isomerase
BsBEST3102_37890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3102_37900	COG1971	Probably functions as a manganese efflux pump
BsBEST3102_37910	COG0009	L-threonylcarbamoyladenylate synthase
BsBEST3102_37920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BsBEST3102_37960	COG2890	protein-(glutamine-N5) methyltransferase activity
BsBEST3102_37970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BsBEST3102_37980	COG0346	lactoylglutathione lyase activity
BsBEST3102_37990	COG0789	Transcriptional regulator
BsBEST3102_38000	COG0679	Auxin Efflux Carrier
BsBEST3102_38010	COG0281	malic enzyme
BsBEST3102_38030	COG1435	thymidine kinase activity
BsBEST3102_38050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BsBEST3102_38060	COG1494	fructose-1,6-bisphosphatase
BsBEST3102_38070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3102_38080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BsBEST3102_38090	COG0191	fructose-bisphosphate aldolase activity
BsBEST3102_38100	COG2204	response regulator
BsBEST3102_38110	COG4821	SIS domain
BsBEST3102_38120	COG0504	CTP synthase activity
BsBEST3102_38130	COG3343	RNA polymerase activity
BsBEST3102_38140	COG1960	acyl-CoA dehydrogenase activity
BsBEST3102_38150	COG0247	lactate metabolic process
BsBEST3102_38150	COG2181	nitrate reductase activity
BsBEST3102_38160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3102_38170	COG4294	response to UV
BsBEST3102_38190	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3102_38200	COG1132	(ABC) transporter
BsBEST3102_38210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3102_38220	COG2181	nitrate reductase activity
BsBEST3102_38230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BsBEST3102_38240	COG1140	nitrate reductase beta subunit
BsBEST3102_38250	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BsBEST3102_38260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3102_38280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3102_38290	COG2223	nitrite transmembrane transporter activity
BsBEST3102_38300	COG0018	arginyl-trna synthetase
BsBEST3102_38310	COG4506	Protein conserved in bacteria
BsBEST3102_38330	COG0535	radical SAM domain protein
BsBEST3102_38350	COG1131	(ABC) transporter
BsBEST3102_38360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3102_38370	COG0612	Peptidase, M16
BsBEST3102_38380	COG0612	Peptidase, M16
BsBEST3102_38400	COG3391	amine dehydrogenase activity
BsBEST3102_38410	COG3391	amine dehydrogenase activity
BsBEST3102_38420	COG0457	Tetratricopeptide repeat
BsBEST3102_38440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3102_38450	COG0010	Belongs to the arginase family
BsBEST3102_38460	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BsBEST3102_38470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3102_38490	COG1994	Peptidase M50
BsBEST3102_38500	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3102_38510	COG1846	Transcriptional regulator
BsBEST3102_38520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3102_38530	COG0477	Major facilitator Superfamily
BsBEST3102_38540	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3102_38550	COG3465	dGTPase activity
BsBEST3102_38560	COG1078	dGTPase activity
BsBEST3102_38570	COG4844	belongs to the
BsBEST3102_38590	COG0697	spore germination
BsBEST3102_38600	COG0095	Lipoate-protein ligase
BsBEST3102_38610	COG0583	DNA-binding transcription factor activity
BsBEST3102_38620	COG0280	phosphate acetyltransferase
BsBEST3102_38630	COG3253	May function as heme-dependent peroxidase
BsBEST3102_38640	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_38650	COG0436	Aminotransferase
BsBEST3102_38660	COG2814	Major facilitator Superfamily
BsBEST3102_38670	COG0151	Belongs to the GarS family
BsBEST3102_38680	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_38690	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3102_38700	COG0077	Prephenate dehydratase
BsBEST3102_38710	COG2814	Major facilitator Superfamily
BsBEST3102_38720	COG0833	amino acid
BsBEST3102_38730	COG4187	Peptidase family M20/M25/M40
BsBEST3102_38740	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_38750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3102_38770	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3102_38780	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3102_38790	COG1091	dTDP-4-dehydrorhamnose reductase activity
BsBEST3102_38800	COG1088	dTDP-glucose 4,6-dehydratase activity
BsBEST3102_38810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BsBEST3102_38820	COG3980	spore coat polysaccharide biosynthesis protein
BsBEST3102_38830	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BsBEST3102_38840	COG2089	acid synthase
BsBEST3102_38850	COG0456	acetyltransferase
BsBEST3102_38860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3102_38870	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3102_38880	COG0463	Glycosyl transferase, family 2
BsBEST3102_38900	COG2363	Small membrane protein
BsBEST3102_38910	COG2233	PERMEase
BsBEST3102_38930	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_38940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BsBEST3102_38950	COG1216	Glycosyl transferase, family 2
BsBEST3102_38980	COG1695	Transcriptional regulator
BsBEST3102_38990	COG0351	phosphomethylpyrimidine kinase
BsBEST3102_39010	COG1621	beta-fructofuranosidase activity
BsBEST3102_39020	COG1263	PTS System
BsBEST3102_39020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3102_39030	COG2116	formate transmembrane transporter activity
BsBEST3102_39040	COG3711	transcriptional antiterminator
BsBEST3102_39060	COG1404	Belongs to the peptidase S8 family
BsBEST3102_39070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3102_39080	COG0778	Nitroreductase
BsBEST3102_39090	COG0772	Belongs to the SEDS family
BsBEST3102_39110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3102_39120	COG1845	cytochrome c oxidase, subunit III
BsBEST3102_39130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3102_39140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3102_39150	COG2261	transglycosylase associated protein
BsBEST3102_39160	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BsBEST3102_39170	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BsBEST3102_39180	COG2246	polysaccharide biosynthetic process
BsBEST3102_39190	COG1309	transcriptional regulator
BsBEST3102_39210	COG3162	membrane
BsBEST3102_39220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3102_39230	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3102_39240	COG2837	iron assimilation
BsBEST3102_39250	COG2822	iron ion transport
BsBEST3102_39260	COG0672	)-iron permease
BsBEST3102_39270	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3102_39280	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BsBEST3102_39290	COG0583	DNA-binding transcription factor activity
BsBEST3102_39300	COG1380	Effector of murein hydrolase LrgA
BsBEST3102_39310	COG1346	cytolysis
BsBEST3102_39320	COG2814	Major facilitator Superfamily
BsBEST3102_39330	COG4895	conserved protein (DUF2196)
BsBEST3102_39340	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BsBEST3102_39350	COG0346	lactoylglutathione lyase activity
BsBEST3102_39370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3102_39380	COG1404	Belongs to the peptidase S8 family
BsBEST3102_39390	COG1263	PTS System
BsBEST3102_39390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3102_39400	COG3711	transcriptional antiterminator
BsBEST3102_39410	COG1442	glycosyl transferase family 8
BsBEST3102_39420	COG5522	Integral membrane protein (intg_mem_TP0381)
BsBEST3102_39430	COG1846	Transcriptional regulator
BsBEST3102_39440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3102_39450	COG2234	aminopeptidase activity
BsBEST3102_39460	COG2357	RelA SpoT domain protein
BsBEST3102_39470	COG1575	Belongs to the MenA family. Type 1 subfamily
BsBEST3102_39480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3102_39490	COG1696	Membrane protein involved in D-alanine export
BsBEST3102_39500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3102_39510	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BsBEST3102_39520	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3102_39530	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3102_39540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3102_39550	COG1486	melibiose metabolic process
BsBEST3102_39560	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3102_39570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3102_39580	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3102_39590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3102_39590	COG3711	transcriptional antiterminator
BsBEST3102_39610	COG2094	Belongs to the DNA glycosylase MPG family
BsBEST3102_39620	COG0753	catalase activity
BsBEST3102_39630	COG2814	Major facilitator Superfamily
BsBEST3102_39640	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3102_39650	COG1131	(ABC) transporter
BsBEST3102_39690	COG1595	DNA-templated transcription, initiation
BsBEST3102_39700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3102_39710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BsBEST3102_39720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BsBEST3102_39730	COG4988	ABC transporter
BsBEST3102_39740	COG1294	oxidase, subunit
BsBEST3102_39750	COG1271	oxidase subunit
BsBEST3102_39760	COG3493	citrate carrier protein
BsBEST3102_39770	COG0501	Belongs to the peptidase M48B family
BsBEST3102_39790	COG0726	polysaccharide deacetylase
BsBEST3102_39800	COG3842	ATPase activity
BsBEST3102_39810	COG2508	Transcriptional regulator
BsBEST3102_39820	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_39830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3102_39850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BsBEST3102_39860	COG1881	PFAM PEBP family protein
BsBEST3102_39870	COG0583	DNA-binding transcription factor activity
BsBEST3102_39890	COG4585	Histidine kinase
BsBEST3102_39900	COG2197	response regulator
BsBEST3102_39910	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3102_39930	COG4894	glucomannan catabolic process
BsBEST3102_39940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3102_39950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3102_39960	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_39970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3102_39980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3102_39990	COG2610	gluconate transmembrane transporter activity
BsBEST3102_40000	COG0500	methyltransferase
BsBEST3102_40010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3102_40040	COG0693	protein deglycase activity
BsBEST3102_40040	COG0753	catalase activity
BsBEST3102_40050	COG2851	Citrate transporter
BsBEST3102_40060	COG2273	Hydrolase Family 16
BsBEST3102_40070	COG3711	transcriptional antiterminator
BsBEST3102_40090	COG2270	Major facilitator Superfamily
BsBEST3102_40100	COG0513	Belongs to the DEAD box helicase family
BsBEST3102_40110	COG2755	lipolytic protein G-D-S-L family
BsBEST3102_40110	COG3401	FG-GAP repeat protein
BsBEST3102_40350	COG0697	spore germination
BsBEST3102_40380	COG0589	response to stress
BsBEST3102_40390	COG2723	6-phospho-beta-galactosidase activity
BsBEST3102_40400	COG2723	6-phospho-beta-galactosidase activity
BsBEST3102_40410	COG1263	PTS System
BsBEST3102_40410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3102_40410	COG2190	(PTS) system
BsBEST3102_40440	COG5444	nuclease activity
BsBEST3102_40470	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3102_40500	COG2986	histidine ammonia-lyase
BsBEST3102_40510	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BsBEST3102_40520	COG1228	amidohydrolase
BsBEST3102_40530	COG0010	Belongs to the arginase family
BsBEST3102_40540	COG0833	amino acid
BsBEST3102_40550	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BsBEST3102_40560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3102_40570	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BsBEST3102_40580	COG2390	Transcriptional regulator
BsBEST3102_40600	COG3192	ethanolamine utilization protein
BsBEST3102_40610	COG2079	MmgE PrpD family protein
BsBEST3102_40620	COG1473	amidohydrolase
BsBEST3102_40630	COG1126	abc transporter atp-binding protein
BsBEST3102_40640	COG0765	amino acid transport
BsBEST3102_40650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3102_40660	COG0456	acetyltransferase
BsBEST3102_40670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3102_40690	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BsBEST3102_40700	COG0561	phosphatase activity
BsBEST3102_40760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3102_40770	COG5294	Protein conserved in bacteria
BsBEST3102_40780	COG0577	efflux transmembrane transporter activity
BsBEST3102_40790	COG0577	efflux transmembrane transporter activity
BsBEST3102_40800	COG1136	(ABC) transporter
BsBEST3102_40810	COG1136	(ABC) transporter
BsBEST3102_40820	COG2205	protein histidine kinase activity
BsBEST3102_40830	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_40840	COG0191	fructose-bisphosphate aldolase activity
BsBEST3102_40850	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3102_40860	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3102_40870	COG0673	inositol 2-dehydrogenase activity
BsBEST3102_40880	COG2814	Major facilitator Superfamily
BsBEST3102_40890	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3102_40900	COG3962	Belongs to the TPP enzyme family
BsBEST3102_40910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3102_40920	COG3718	enzyme involved in inositol metabolism
BsBEST3102_40930	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_40940	COG1349	DNA-binding transcription factor activity
BsBEST3102_40950	COG0667	Aldo Keto reductase
BsBEST3102_40980	COG2814	Major facilitator Superfamily
BsBEST3102_40990	COG0326	Molecular chaperone. Has ATPase activity
BsBEST3102_41010	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_41020	COG1309	transcriptional regulator
BsBEST3102_41030	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3102_41040	COG0456	acetyltransferase
BsBEST3102_41050	COG2850	peptidyl-arginine hydroxylation
BsBEST3102_41060	COG2226	methyltransferase
BsBEST3102_41090	COG0367	asparagine synthase
BsBEST3102_41100	COG2814	Major facilitator Superfamily
BsBEST3102_41110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BsBEST3102_41130	COG1714	RDD family
BsBEST3102_41140	COG2311	Membrane
BsBEST3102_41150	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3102_41160	COG1309	transcriptional regulator
BsBEST3102_41170	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3102_41180	COG1846	Transcriptional regulator
BsBEST3102_41190	COG1380	Effector of murein hydrolase LrgA
BsBEST3102_41200	COG1346	cytolysis
BsBEST3102_41210	COG5039	Polysaccharide pyruvyl transferase
BsBEST3102_41220	COG1929	Belongs to the glycerate kinase type-1 family
BsBEST3102_41230	COG1802	Transcriptional regulator
BsBEST3102_41240	COG1070	Carbohydrate kinase
BsBEST3102_41250	COG2610	gluconate transmembrane transporter activity
BsBEST3102_41260	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3102_41270	COG0450	alkyl hydroperoxide reductase
BsBEST3102_41280	COG3634	alkyl hydroperoxide reductase activity
BsBEST3102_41290	COG2723	6-phospho-beta-galactosidase activity
BsBEST3102_41300	COG2190	(PTS) system
BsBEST3102_41310	COG2188	Transcriptional regulator
BsBEST3102_41340	COG1131	(ABC) transporter
BsBEST3102_41350	COG1994	Peptidase M50
BsBEST3102_41360	COG0535	radical SAM domain protein
BsBEST3102_41380	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BsBEST3102_41390	COG5293	efflux transmembrane transporter activity
BsBEST3102_41410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3102_41420	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BsBEST3102_41450	COG1063	alcohol dehydrogenase
BsBEST3102_41490	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BsBEST3102_41500	COG0456	acetyltransferase
BsBEST3102_41510	COG0457	Tetratricopeptide repeat
BsBEST3102_41520	COG0010	Belongs to the arginase family
BsBEST3102_41530	COG0833	amino acid
BsBEST3102_41540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3102_41550	COG3829	transcription factor binding
BsBEST3102_41560	COG5002	protein histidine kinase activity
BsBEST3102_41580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3102_41590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BsBEST3102_41600	COG4853	Protein conserved in bacteria
BsBEST3102_41610	COG4863	YycH protein
BsBEST3102_41620	COG5002	protein histidine kinase activity
BsBEST3102_41630	COG0745	RESPONSE REGULATOR receiver
BsBEST3102_41650	COG0346	lactoylglutathione lyase activity
BsBEST3102_41660	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3102_41690	COG3093	addiction module antidote protein HigA
BsBEST3102_41700	COG2807	transmembrane transport
BsBEST3102_41710	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3102_41720	COG0359	binds to the 23S rRNA
BsBEST3102_41730	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BsBEST3102_41740	COG4241	membrane
BsBEST3102_41760	COG5577	PFAM Coat F domain
BsBEST3102_41770	COG1733	regulation of RNA biosynthetic process
BsBEST3102_41780	COG1227	inorganic diphosphatase activity
BsBEST3102_41810	COG2271	Major facilitator Superfamily
BsBEST3102_41880	COG1131	(ABC) transporter
BsBEST3102_41900	COG4319	ketosteroid isomerase
BsBEST3102_41910	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3102_41920	COG2814	Major facilitator Superfamily
BsBEST3102_41930	COG0583	DNA-binding transcription factor activity
BsBEST3102_41940	COG2153	protein acetylation
BsBEST3102_41960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3102_41970	COG1846	Transcriptional regulator
BsBEST3102_41980	COG2153	protein acetylation
BsBEST3102_41990	COG2364	Membrane
BsBEST3102_42000	COG0456	acetyltransferase
BsBEST3102_42010	COG2315	Protein conserved in bacteria
BsBEST3102_42020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3102_42030	COG2814	Major facilitator Superfamily
BsBEST3102_42040	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3102_42050	COG0789	Transcriptional regulator
BsBEST3102_42060	COG0697	spore germination
BsBEST3102_42070	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3102_42080	COG1266	CAAX protease self-immunity
BsBEST3102_42090	COG0477	Major facilitator Superfamily
BsBEST3102_42090	COG2814	Major facilitator Superfamily
BsBEST3102_42100	COG0110	maltose O-acetyltransferase activity
BsBEST3102_42110	COG0346	lactoylglutathione lyase activity
BsBEST3102_42120	COG1609	Transcriptional regulator
BsBEST3102_42130	COG0708	Exodeoxyribonuclease III
BsBEST3102_42140	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BsBEST3102_42150	COG0629	single-stranded DNA binding
BsBEST3102_42160	COG0360	Binds together with S18 to 16S ribosomal RNA
BsBEST3102_42170	COG0012	GTP binding
BsBEST3102_42180	COG0243	molybdopterin cofactor binding
BsBEST3102_42190	COG4481	Protein conserved in bacteria
BsBEST3102_42200	COG3949	Membrane
BsBEST3102_42220	COG1475	DNA binding
BsBEST3102_42230	COG1192	Involved in chromosome partitioning
BsBEST3102_42250	COG1475	DNA binding
BsBEST3102_42260	COG0357	Ribosomal RNA small subunit methyltransferase G
BsBEST3102_42270	COG0445	tRNA wobble uridine modification
BsBEST3102_42280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BsBEST3102_42290	COG1847	R3H domain protein
BsBEST3102_42300	COG0706	membrane insertase activity
BsBEST3102_42310	COG0594	ribonuclease P activity