locus-tag	class	description
BsBEST3106_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BsBEST3106_00020	COG0592	DNA-directed DNA polymerase activity
BsBEST3106_00030	COG2501	S4 domain
BsBEST3106_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BsBEST3106_00060	COG0187	DNA topoisomerase II activity
BsBEST3106_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3106_00090	COG0516	GMP reductase activity
BsBEST3106_00090	COG0517	IMP dehydrogenase activity
BsBEST3106_00100	COG1686	Belongs to the peptidase S11 family
BsBEST3106_00110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BsBEST3106_00120	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BsBEST3106_00130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BsBEST3106_00140	COG1428	Deoxynucleoside kinase
BsBEST3106_00150	COG1428	Deoxynucleoside kinase
BsBEST3106_00160	COG1388	LysM domain
BsBEST3106_00160	COG3858	chitin binding
BsBEST3106_00170	COG1335	isochorismatase
BsBEST3106_00180	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3106_00190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BsBEST3106_00200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BsBEST3106_00210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BsBEST3106_00250	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BsBEST3106_00260	COG3853	Toxic anion resistance protein (TelA)
BsBEST3106_00270	COG1982	Orn Lys Arg decarboxylase major
BsBEST3106_00280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3106_00290	COG3870	Protein conserved in bacteria
BsBEST3106_00300	COG1728	Protein conserved in bacteria
BsBEST3106_00310	COG0470	DNA polymerase III
BsBEST3106_00320	COG1774	PSP1 C-terminal conserved region
BsBEST3106_00330	COG4467	Involved in initiation control of chromosome replication
BsBEST3106_00340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BsBEST3106_00350	COG2827	Endonuclease containing a URI domain
BsBEST3106_00360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BsBEST3106_00370	COG2002	toxin-antitoxin pair type II binding
BsBEST3106_00380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3106_00380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3106_00390	COG0084	hydrolase, TatD family'
BsBEST3106_00400	COG3584	3D domain protein
BsBEST3106_00400	COG3583	domain protein
BsBEST3106_00410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3106_00420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BsBEST3106_00440	COG4466	Protein conserved in bacteria
BsBEST3106_00460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BsBEST3106_00470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3106_00480	COG0251	oxidation-reduction process
BsBEST3106_00490	COG2088	sporulation resulting in formation of a cellular spore
BsBEST3106_00500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BsBEST3106_00510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BsBEST3106_00520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BsBEST3106_00530	COG0193	aminoacyl-tRNA hydrolase activity
BsBEST3106_00550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BsBEST3106_00560	COG2002	toxin-antitoxin pair type II binding
BsBEST3106_00570	COG2244	polysaccharide biosynthetic process
BsBEST3106_00580	COG3956	TIGRFAM MazG family protein
BsBEST3106_00590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BsBEST3106_00620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BsBEST3106_00630	COG1098	S1 RNA binding domain
BsBEST3106_00640	COG2208	phosphoserine phosphatase activity
BsBEST3106_00650	COG2304	oxidoreductase activity
BsBEST3106_00660	COG0515	serine threonine protein kinase
BsBEST3106_00670	COG0037	tRNA processing
BsBEST3106_00680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BsBEST3106_00690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3106_00700	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BsBEST3106_00710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BsBEST3106_00720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3106_00730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3106_00740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3106_00750	COG0512	Glutamine amidotransferase of anthranilate synthase
BsBEST3106_00760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3106_00770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BsBEST3106_00780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BsBEST3106_00790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BsBEST3106_00800	COG1396	sequence-specific DNA binding
BsBEST3106_00810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3106_00820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BsBEST3106_00830	COG4463	regulation of RNA biosynthetic process
BsBEST3106_00840	COG3880	PFAM UvrB UvrC protein
BsBEST3106_00850	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BsBEST3106_00860	COG0542	response to heat
BsBEST3106_00870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BsBEST3106_00880	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BsBEST3106_00890	COG4956	integral membrane protein (PIN domain superfamily)
BsBEST3106_00900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BsBEST3106_00910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BsBEST3106_00920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BsBEST3106_00930	COG1045	serine acetyltransferase
BsBEST3106_00940	COG0215	cysteine-tRNA ligase activity
BsBEST3106_00950	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BsBEST3106_00960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3106_00970	COG3688	RNA-binding protein containing a PIN domain
BsBEST3106_00980	COG1595	DNA-templated transcription, initiation
BsBEST3106_00990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3106_01000	COG0250	Participates in transcription elongation, termination and antitermination
BsBEST3106_01020	COG0081	regulation of translation
BsBEST3106_01030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BsBEST3106_01050	COG2813	Specifically methylates the guanine in position
BsBEST3106_01060	COG0085	RNA polymerase activity
BsBEST3106_01070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BsBEST3106_01080	COG1358	cellular component organization or biogenesis
BsBEST3106_01090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BsBEST3106_01100	COG0049	tRNA binding
BsBEST3106_01110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BsBEST3106_01120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BsBEST3106_01130	COG0596	Alpha beta hydrolase
BsBEST3106_01150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BsBEST3106_01160	COG0088	Forms part of the polypeptide exit tunnel
BsBEST3106_01180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BsBEST3106_01210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BsBEST3106_01220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BsBEST3106_01240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BsBEST3106_01250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BsBEST3106_01270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BsBEST3106_01290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BsBEST3106_01300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BsBEST3106_01310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BsBEST3106_01340	COG0200	Binds to the 23S rRNA
BsBEST3106_01350	COG0201	protein transport
BsBEST3106_01360	COG0563	adenylate kinase activity
BsBEST3106_01370	COG0024	Methionine aminopeptidase
BsBEST3106_01390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BsBEST3106_01400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BsBEST3106_01410	COG0202	RNA polymerase activity
BsBEST3106_01420	COG0203	ribosomal protein L17
BsBEST3106_01430	COG1122	ATPase activity
BsBEST3106_01440	COG1122	ATPase activity
BsBEST3106_01450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3106_01460	COG0101	tRNA pseudouridine synthase activity
BsBEST3106_01470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BsBEST3106_01480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BsBEST3106_01490	COG2226	methyltransferase
BsBEST3106_01510	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_01520	COG0489	protein tyrosine kinase activity
BsBEST3106_01540	COG2194	sulfuric ester hydrolase activity
BsBEST3106_01550	COG0726	polysaccharide deacetylase
BsBEST3106_01560	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3106_01580	COG0385	Bile acid
BsBEST3106_01590	COG2819	hydrolase of the alpha beta superfamily
BsBEST3106_01600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3106_01610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3106_01620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3106_01630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3106_01630	COG2207	Transcriptional regulator
BsBEST3106_01640	COG3876	Protein conserved in bacteria
BsBEST3106_01650	COG1472	Belongs to the glycosyl hydrolase 3 family
BsBEST3106_01660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3106_01670	COG1263	PTS System
BsBEST3106_01670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3106_01680	COG1737	Transcriptional regulator
BsBEST3106_01690	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BsBEST3106_01700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3106_01710	COG1683	Conserved Protein
BsBEST3106_01720	COG1595	DNA-templated transcription, initiation
BsBEST3106_01730	COG5662	AntiSigma factor
BsBEST3106_01740	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3106_01750	COG4856	YbbR-like protein
BsBEST3106_01760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3106_01770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BsBEST3106_01790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3106_01800	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3106_01810	COG2169	Transcriptional regulator
BsBEST3106_01820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3106_01830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3106_01840	COG3002	Belongs to the UPF0753 family
BsBEST3106_01850	COG0288	reversible hydration of carbon dioxide
BsBEST3106_01870	COG5609	conserved protein (DUF2294)
BsBEST3106_01880	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_01890	COG0642	Histidine kinase
BsBEST3106_01910	COG0515	serine threonine protein kinase
BsBEST3106_01940	COG1113	amino acid transport
BsBEST3106_01970	COG2602	Beta-lactamase
BsBEST3106_01980	COG2124	cytochrome p450
BsBEST3106_02000	COG0531	amino acid
BsBEST3106_02010	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3106_02020	COG2271	Major facilitator Superfamily
BsBEST3106_02040	COG0456	acetyltransferase
BsBEST3106_02040	COG1846	Transcriptional regulator
BsBEST3106_02050	COG2271	Major facilitator Superfamily
BsBEST3106_02070	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_02080	COG0697	spore germination
BsBEST3106_02090	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3106_02090	COG2207	Transcriptional regulator
BsBEST3106_02100	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BsBEST3106_02110	COG3591	Belongs to the peptidase S1B family
BsBEST3106_02130	COG0596	Alpha beta hydrolase
BsBEST3106_02140	COG1183	phosphatidylcholine synthase activity
BsBEST3106_02150	COG0586	Pfam SNARE associated Golgi protein
BsBEST3106_02160	COG0688	phosphatidylethanolamine metabolic process
BsBEST3106_02180	COG2312	Erythromycin esterase
BsBEST3106_02190	COG2207	Transcriptional regulator
BsBEST3106_02200	COG1054	Belongs to the UPF0176 family
BsBEST3106_02210	COG1301	dicarboxylic acid transport
BsBEST3106_02220	COG1263	PTS System
BsBEST3106_02220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3106_02220	COG2190	(PTS) system
BsBEST3106_02230	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3106_02240	COG2188	Transcriptional regulator
BsBEST3106_02260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3106_02270	COG0833	amino acid
BsBEST3106_02280	COG2040	homocysteine
BsBEST3106_02290	COG1115	amino acid carrier protein
BsBEST3106_02300	COG1115	amino acid carrier protein
BsBEST3106_02310	COG2066	Belongs to the glutaminase family
BsBEST3106_02320	COG4191	Histidine kinase
BsBEST3106_02330	COG0784	Response regulator, receiver
BsBEST3106_02340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3106_02350	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_02360	COG2271	Major facilitator Superfamily
BsBEST3106_02370	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3106_02380	COG2186	Transcriptional regulator
BsBEST3106_02390	COG2721	sulfolactate sulfo-lyase activity
BsBEST3106_02400	COG3173	Aminoglycoside phosphotransferase
BsBEST3106_02420	COG0697	spore germination
BsBEST3106_02430	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_02440	COG2205	protein histidine kinase activity
BsBEST3106_02450	COG1131	(ABC) transporter
BsBEST3106_02480	COG3773	Cell wall hydrolase
BsBEST3106_02490	COG2304	oxidoreductase activity
BsBEST3106_02500	COG3540	Alkaline phosphatase
BsBEST3106_02510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3106_02520	COG0805	protein transport
BsBEST3106_02530	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BsBEST3106_02540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3106_02550	COG0477	Major facilitator Superfamily
BsBEST3106_02560	COG1309	transcriptional regulator
BsBEST3106_02570	COG0252	asparaginase activity
BsBEST3106_02580	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3106_02590	COG1714	RDD family
BsBEST3106_02600	COG1405	negative regulation of cell septum assembly
BsBEST3106_02600	COG3012	SEC-C Motif Domain Protein
BsBEST3106_02610	COG3290	protein histidine kinase activity
BsBEST3106_02620	COG3279	Response regulator of the LytR AlgR family
BsBEST3106_02630	COG4555	ABC transporter
BsBEST3106_02640	COG1668	transmembrane transport
BsBEST3106_02650	COG0667	Aldo Keto reductase
BsBEST3106_02670	COG1595	DNA-templated transcription, initiation
BsBEST3106_02680	COG1595	DNA-templated transcription, initiation
BsBEST3106_02690	COG1876	peptidase activity
BsBEST3106_02700	COG0457	Tetratricopeptide repeat
BsBEST3106_02710	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_02720	COG0366	Alpha amylase catalytic
BsBEST3106_02730	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3106_02740	COG1121	(ABC) transporter
BsBEST3106_02750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3106_02760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3106_02770	COG2310	stress, protein
BsBEST3106_02780	COG2310	stress, protein
BsBEST3106_02790	COG2310	stress, protein
BsBEST3106_02800	COG0861	Integral membrane protein TerC family
BsBEST3106_02820	COG3853	Toxic anion resistance protein (TelA)
BsBEST3106_02830	COG0477	Major facilitator Superfamily
BsBEST3106_02840	COG2814	Major facilitator Superfamily
BsBEST3106_02850	COG0640	Transcriptional regulator
BsBEST3106_02860	COG0517	IMP dehydrogenase activity
BsBEST3106_02860	COG4175	Glycine betaine
BsBEST3106_02870	COG4176	ABC-type proline glycine betaine transport system permease component
BsBEST3106_02880	COG2113	Glycine betaine
BsBEST3106_02890	COG1473	amidohydrolase
BsBEST3106_02900	COG1288	antiporter activity
BsBEST3106_02920	COG0366	Alpha amylase catalytic
BsBEST3106_02930	COG0366	Alpha amylase catalytic
BsBEST3106_02940	COG0039	L-malate dehydrogenase activity
BsBEST3106_02950	COG1620	l-lactate permease
BsBEST3106_02960	COG1620	l-lactate permease
BsBEST3106_02970	COG3403	YqcI/YcgG family
BsBEST3106_02990	COG1113	amino acid transport
BsBEST3106_03000	COG1113	amino acid transport
BsBEST3106_03010	COG3665	Urea carboxylase-associated protein
BsBEST3106_03020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BsBEST3106_03030	COG1660	Displays ATPase and GTPase activities
BsBEST3106_03040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BsBEST3106_03050	COG2226	methyltransferase
BsBEST3106_03060	COG0583	DNA-binding transcription factor activity
BsBEST3106_03070	COG3458	cephalosporin-C deacetylase activity
BsBEST3106_03080	COG3541	Predicted nucleotidyltransferase
BsBEST3106_03090	COG0506	proline dehydrogenase activity
BsBEST3106_03100	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_03110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3106_03120	COG2508	Transcriptional regulator
BsBEST3106_03130	COG3689	TIGRFAM TIGR03943 family protein
BsBEST3106_03140	COG0701	Predicted permease
BsBEST3106_03150	COG2267	carboxylic ester hydrolase activity
BsBEST3106_03160	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3106_03170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3106_03170	COG1587	Uroporphyrinogen-III synthase
BsBEST3106_03180	COG2146	nitrite reductase [NAD(P)H] activity
BsBEST3106_03190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3106_03200	COG0243	molybdopterin cofactor binding
BsBEST3106_03210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3106_03220	COG2223	nitrite transmembrane transporter activity
BsBEST3106_03230	COG1469	GTP cyclohydrolase I activity
BsBEST3106_03240	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3106_03250	COG0523	cobalamin synthesis protein
BsBEST3106_03260	COG0765	amino acid transport
BsBEST3106_03270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3106_03290	COG1714	RDD family
BsBEST3106_03310	COG2723	6-phospho-beta-galactosidase activity
BsBEST3106_03330	COG3209	COG3209 Rhs family protein
BsBEST3106_03340	COG0840	transmembrane signaling receptor activity
BsBEST3106_03340	COG3290	protein histidine kinase activity
BsBEST3106_03350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BsBEST3106_03360	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BsBEST3106_03370	COG1733	regulation of RNA biosynthetic process
BsBEST3106_03380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_03390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_03400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_03410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_03420	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BsBEST3106_03430	COG2814	Major facilitator Superfamily
BsBEST3106_03450	COG0697	spore germination
BsBEST3106_03460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3106_03490	COG2364	Membrane
BsBEST3106_03500	COG1126	abc transporter atp-binding protein
BsBEST3106_03510	COG0765	amino acid transport
BsBEST3106_03520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3106_03530	COG0583	DNA-binding transcription factor activity
BsBEST3106_03540	COG0163	prenyltransferase activity
BsBEST3106_03550	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BsBEST3106_03580	COG0596	Alpha beta hydrolase
BsBEST3106_03590	COG3104	oligopeptide transport
BsBEST3106_03600	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3106_03620	COG0697	spore germination
BsBEST3106_03640	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3106_03650	COG1136	(ABC) transporter
BsBEST3106_03660	COG0577	efflux transmembrane transporter activity
BsBEST3106_03670	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_03680	COG3850	Histidine kinase
BsBEST3106_03680	COG5002	protein histidine kinase activity
BsBEST3106_03690	COG0457	Tetratricopeptide repeat
BsBEST3106_03710	COG0527	aspartate kinase activity
BsBEST3106_03720	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3106_03730	COG4605	iron ion homeostasis
BsBEST3106_03740	COG4604	ABC transporter, ATP-binding protein
BsBEST3106_03750	COG4607	ABC-type enterochelin transport system periplasmic component
BsBEST3106_03760	COG2814	Major facilitator Superfamily
BsBEST3106_03770	COG1309	transcriptional regulator
BsBEST3106_03780	COG0778	Nitroreductase
BsBEST3106_03790	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3106_03800	COG0640	Transcriptional regulator
BsBEST3106_03810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3106_03820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BsBEST3106_03830	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_03840	COG4975	Glucose uptake
BsBEST3106_03850	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_03860	COG4549	nuclear export factor GLE1
BsBEST3106_03870	COG2372	response to copper ion
BsBEST3106_03870	COG1276	copper resistance
BsBEST3106_03880	COG1349	DNA-binding transcription factor activity
BsBEST3106_03900	COG2213	PTS system mannitol-specific
BsBEST3106_03910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3106_03920	COG0246	Mannitol dehydrogenase
BsBEST3106_03930	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3106_03950	COG0681	Belongs to the peptidase S26 family
BsBEST3106_03960	COG0412	Dienelactone hydrolase
BsBEST3106_03970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3106_03990	COG0561	phosphatase activity
BsBEST3106_04000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3106_04010	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3106_04020	COG4336	lyase activity
BsBEST3106_04030	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3106_04040	COG1984	allophanate hydrolase subunit 2
BsBEST3106_04050	COG1414	Transcriptional regulator
BsBEST3106_04060	COG2755	lipolytic protein G-D-S-L family
BsBEST3106_04080	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3106_04090	COG0768	penicillin binding
BsBEST3106_04100	COG4989	oxidoreductase activity
BsBEST3106_04110	COG3711	transcriptional antiterminator
BsBEST3106_04120	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3106_04130	COG2226	methyltransferase
BsBEST3106_04140	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_04150	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3106_04160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3106_04170	COG3871	stress protein (general stress protein 26)
BsBEST3106_04190	COG2814	Major facilitator Superfamily
BsBEST3106_04200	COG1522	sequence-specific DNA binding
BsBEST3106_04210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3106_04210	COG0551	DNA topoisomerase type I activity
BsBEST3106_04220	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BsBEST3106_04230	COG3706	GGDEF domain
BsBEST3106_04240	COG5298	Protein conserved in bacteria
BsBEST3106_04250	COG1215	transferase activity, transferring glycosyl groups
BsBEST3106_04270	COG0531	amino acid
BsBEST3106_04280	COG0494	nUDIX hydrolase
BsBEST3106_04290	COG0028	Belongs to the TPP enzyme family
BsBEST3106_04320	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3106_04330	COG2261	transglycosylase associated protein
BsBEST3106_04340	COG4876	unkown
BsBEST3106_04350	COG2217	Heavy metal translocating P-type atpase
BsBEST3106_04360	COG3729	General stress protein
BsBEST3106_04370	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3106_04380	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3106_04390	COG3546	catalase activity
BsBEST3106_04400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BsBEST3106_04410	COG3290	protein histidine kinase activity
BsBEST3106_04420	COG4565	transcriptional regulatory protein
BsBEST3106_04430	COG1301	dicarboxylic acid transport
BsBEST3106_04440	COG0628	permease
BsBEST3106_04460	COG1131	(ABC) transporter
BsBEST3106_04470	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3106_04490	COG1960	acyl-CoA dehydrogenase activity
BsBEST3106_04520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3106_04530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_04540	COG1181	Belongs to the D-alanine--D-alanine ligase family
BsBEST3106_04550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BsBEST3106_04560	COG0513	Belongs to the DEAD box helicase family
BsBEST3106_04570	COG3402	PFAM membrane-flanked domain
BsBEST3106_04580	COG3428	Bacterial PH domain
BsBEST3106_04590	COG0705	Rhomboid family
BsBEST3106_04600	COG0736	holo-[acyl-carrier-protein] synthase activity
BsBEST3106_04610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BsBEST3106_04620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3106_04630	COG0864	Transcriptional regulator
BsBEST3106_04640	COG2337	Toxic component of a toxin-antitoxin (TA) module
BsBEST3106_04650	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3106_04660	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3106_04670	COG2172	sigma factor antagonist activity
BsBEST3106_04680	COG2208	phosphoserine phosphatase activity
BsBEST3106_04690	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3106_04700	COG2172	sigma factor antagonist activity
BsBEST3106_04710	COG1191	sigma factor activity
BsBEST3106_04720	COG2208	phosphoserine phosphatase activity
BsBEST3106_04750	COG1673	EVE domain
BsBEST3106_04760	COG1846	Transcriptional regulator
BsBEST3106_04770	COG2183	response to ionizing radiation
BsBEST3106_04780	COG3091	SprT-like family
BsBEST3106_04790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3106_04800	COG1522	sequence-specific DNA binding
BsBEST3106_04810	COG1522	sequence-specific DNA binding
BsBEST3106_04820	COG1335	isochorismatase
BsBEST3106_04830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3106_04840	COG2814	Major facilitator Superfamily
BsBEST3106_04880	COG0693	protein deglycase activity
BsBEST3106_04890	COG1278	Cold shock
BsBEST3106_04900	COG1329	Transcriptional regulator
BsBEST3106_04910	COG0697	spore germination
BsBEST3106_04920	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3106_04920	COG2207	Transcriptional regulator
BsBEST3106_04930	COG0697	spore germination
BsBEST3106_04940	COG3708	Transcriptional regulator
BsBEST3106_04940	COG2207	Transcriptional regulator
BsBEST3106_04950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3106_04960	COG0477	Major facilitator Superfamily
BsBEST3106_04980	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BsBEST3106_05000	COG0697	spore germination
BsBEST3106_05010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3106_05020	COG2030	dehydratase
BsBEST3106_05030	COG3545	Serine hydrolase
BsBEST3106_05040	COG1733	regulation of RNA biosynthetic process
BsBEST3106_05050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3106_05060	COG1733	regulation of RNA biosynthetic process
BsBEST3106_05070	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3106_05080	COG2814	Major facilitator Superfamily
BsBEST3106_05090	COG1309	transcriptional regulator
BsBEST3106_05110	COG0640	Transcriptional regulator
BsBEST3106_05120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3106_05130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3106_05140	COG0697	spore germination
BsBEST3106_05150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3106_05160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3106_05170	COG0640	Transcriptional regulator
BsBEST3106_05180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3106_05200	COG4585	Histidine kinase
BsBEST3106_05210	COG2197	response regulator
BsBEST3106_05220	COG2409	Drug exporters of the RND superfamily
BsBEST3106_05230	COG0596	Alpha beta hydrolase
BsBEST3106_05240	COG1811	Na channel or pump
BsBEST3106_05250	COG0789	Transcriptional regulator
BsBEST3106_05250	COG4978	Transcriptional regulator
BsBEST3106_05260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3106_05270	COG0778	Nitroreductase
BsBEST3106_05280	COG0346	lactoylglutathione lyase activity
BsBEST3106_05290	COG2259	Doxx family
BsBEST3106_05300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_05330	COG2323	membrane
BsBEST3106_05340	COG2323	membrane
BsBEST3106_05350	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3106_05380	COG1309	transcriptional regulator
BsBEST3106_05400	COG0456	acetyltransferase
BsBEST3106_05410	COG0488	(ABC) transporter
BsBEST3106_05420	COG1113	amino acid transport
BsBEST3106_05430	COG2318	DinB family
BsBEST3106_05440	COG1846	Transcriptional regulator
BsBEST3106_05450	COG1033	growth of symbiont in host cell
BsBEST3106_05450	COG2409	Drug exporters of the RND superfamily
BsBEST3106_05460	COG0778	Nitroreductase
BsBEST3106_05470	COG1846	Transcriptional regulator
BsBEST3106_05480	COG2814	Major facilitator Superfamily
BsBEST3106_05490	COG0730	response to heat
BsBEST3106_05500	COG1802	Transcriptional regulator
BsBEST3106_05510	COG1388	LysM domain
BsBEST3106_05510	COG3858	chitin binding
BsBEST3106_05520	COG1819	glycosyl
BsBEST3106_05540	COG1785	Belongs to the alkaline phosphatase family
BsBEST3106_05550	COG5646	InterPro IPR014922
BsBEST3106_05570	COG0454	-acetyltransferase
BsBEST3106_05580	COG1078	dGTPase activity
BsBEST3106_05590	COG1388	LysM domain
BsBEST3106_05600	COG2814	Major facilitator Superfamily
BsBEST3106_05610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3106_05620	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3106_05630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3106_05640	COG2723	6-phospho-beta-galactosidase activity
BsBEST3106_05650	COG2188	Transcriptional regulator
BsBEST3106_05660	COG1940	carbohydrate kinase activity
BsBEST3106_05670	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3106_05680	COG4124	Belongs to the glycosyl hydrolase 26 family
BsBEST3106_05710	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BsBEST3106_05720	COG0802	atpase or kinase
BsBEST3106_05730	COG1214	PFAM Peptidase M22, glycoprotease
BsBEST3106_05740	COG0456	acetyltransferase
BsBEST3106_05750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BsBEST3106_05760	COG0488	(ABC) transporter
BsBEST3106_05770	COG0315	cyclic pyranopterin monophosphate synthase activity
BsBEST3106_05780	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BsBEST3106_05790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3106_05800	COG0805	protein transport
BsBEST3106_05820	COG1266	CAAX protease self-immunity
BsBEST3106_05840	COG0459	protein refolding
BsBEST3106_05870	COG3378	Phage plasmid primase P4 family
BsBEST3106_05900	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3106_05910	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3106_05940	COG1401	restriction endodeoxyribonuclease activity
BsBEST3106_05990	COG1073	alpha beta
BsBEST3106_06000	COG0457	Tetratricopeptide repeat
BsBEST3106_06010	COG1063	alcohol dehydrogenase
BsBEST3106_06020	COG2211	Major facilitator Superfamily
BsBEST3106_06030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3106_06040	COG1842	Phage shock protein A
BsBEST3106_06050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3106_06060	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BsBEST3106_06070	COG4260	virion core protein, lumpy skin disease virus
BsBEST3106_06090	COG2814	Major facilitator Superfamily
BsBEST3106_06100	COG1063	alcohol dehydrogenase
BsBEST3106_06110	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BsBEST3106_06120	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3106_06150	COG2267	carboxylic ester hydrolase activity
BsBEST3106_06170	COG2132	Multicopper oxidase
BsBEST3106_06180	COG1113	amino acid transport
BsBEST3106_06190	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3106_06200	COG0714	Associated with various cellular activities
BsBEST3106_06210	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BsBEST3106_06220	COG1305	Transglutaminase-like
BsBEST3106_06230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BsBEST3106_06230	COG0519	Catalyzes the synthesis of GMP from XMP
BsBEST3106_06240	COG2252	PERMEase
BsBEST3106_06250	COG3064	Membrane
BsBEST3106_06270	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BsBEST3106_06290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BsBEST3106_06300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BsBEST3106_06310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BsBEST3106_06320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BsBEST3106_06330	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3106_06340	COG0047	phosphoribosylformylglycinamidine synthase activity
BsBEST3106_06350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3106_06360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BsBEST3106_06370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BsBEST3106_06380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BsBEST3106_06390	COG0138	bifunctional purine biosynthesis protein purh
BsBEST3106_06400	COG0151	Belongs to the GarS family
BsBEST3106_06410	COG1522	sequence-specific DNA binding
BsBEST3106_06420	COG0531	amino acid
BsBEST3106_06440	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3106_06450	COG1470	cell adhesion involved in biofilm formation
BsBEST3106_06460	COG4496	protein, YerC YecD
BsBEST3106_06470	COG0069	glutamate synthase activity
BsBEST3106_06480	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BsBEST3106_06490	COG0210	DNA helicase
BsBEST3106_06500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BsBEST3106_06510	COG4851	CamS sex pheromone cAM373 precursor
BsBEST3106_06520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3106_06530	COG1285	pathogenesis
BsBEST3106_06540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3106_06550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3106_06560	COG0154	amidase activity
BsBEST3106_06570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3106_06580	COG1309	transcriptional regulator
BsBEST3106_06590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BsBEST3106_06600	COG1597	lipid kinase activity
BsBEST3106_06610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3106_06620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3106_06630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3106_06640	COG1002	Type II restriction enzyme, methylase subunits
BsBEST3106_06650	COG1061	Type III restriction enzyme res subunit
BsBEST3106_06660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BsBEST3106_06700	COG5444	nuclease activity
BsBEST3106_06720	COG3391	amine dehydrogenase activity
BsBEST3106_06730	COG0457	Tetratricopeptide repeat
BsBEST3106_06750	COG0217	transcriptional regulatory protein
BsBEST3106_06770	COG1309	transcriptional regulator
BsBEST3106_06780	COG3631	Ketosteroid isomerase-related protein
BsBEST3106_06790	COG0702	epimerase
BsBEST3106_06820	COG3546	catalase activity
BsBEST3106_06830	COG0454	-acetyltransferase
BsBEST3106_06850	COG5578	integral membrane protein
BsBEST3106_06860	COG2972	Histidine kinase
BsBEST3106_06870	COG2207	Transcriptional regulator
BsBEST3106_06870	COG4753	response regulator
BsBEST3106_06880	COG1653	transport
BsBEST3106_06890	COG1175	transmembrane transport
BsBEST3106_06900	COG0395	ABC-type sugar transport system, permease component
BsBEST3106_06910	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3106_06920	COG2207	Transcriptional regulator
BsBEST3106_06930	COG2755	lipolytic protein G-D-S-L family
BsBEST3106_06950	COG5578	integral membrane protein
BsBEST3106_06960	COG3401	FG-GAP repeat protein
BsBEST3106_06970	COG3401	FG-GAP repeat protein
BsBEST3106_06980	COG2755	lipolytic protein G-D-S-L family
BsBEST3106_06990	COG1874	Beta-galactosidase
BsBEST3106_07010	COG1653	transport
BsBEST3106_07020	COG4209	transmembrane transport
BsBEST3106_07030	COG0395	ABC-type sugar transport system, permease component
BsBEST3106_07040	COG1486	melibiose metabolic process
BsBEST3106_07050	COG2323	membrane
BsBEST3106_07060	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3106_07070	COG0346	lactoylglutathione lyase activity
BsBEST3106_07090	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3106_07110	COG5583	Uncharacterized small protein (DUF2292)
BsBEST3106_07120	COG0670	Belongs to the BI1 family
BsBEST3106_07130	COG0697	spore germination
BsBEST3106_07140	COG1846	Transcriptional regulator
BsBEST3106_07150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3106_07170	COG2124	cytochrome p450
BsBEST3106_07170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3106_07180	COG1368	sulfuric ester hydrolase activity
BsBEST3106_07190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BsBEST3106_07200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3106_07210	COG1442	glycosyl transferase family 8
BsBEST3106_07220	COG1216	Glycosyl transferase, family 2
BsBEST3106_07230	COG1442	glycosyl transferase family 8
BsBEST3106_07240	COG2223	nitrite transmembrane transporter activity
BsBEST3106_07250	COG1011	Hydrolase
BsBEST3106_07260	COG0531	amino acid
BsBEST3106_07270	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_07280	COG0840	transmembrane signaling receptor activity
BsBEST3106_07290	COG0488	(ABC) transporter
BsBEST3106_07310	COG0789	Transcriptional regulator
BsBEST3106_07320	COG2814	Major facilitator Superfamily
BsBEST3106_07340	COG0488	(ABC) transporter
BsBEST3106_07350	COG0513	Belongs to the DEAD box helicase family
BsBEST3106_07360	COG0456	acetyltransferase
BsBEST3106_07370	COG2130	NADP-dependent
BsBEST3106_07390	COG2211	Major facilitator Superfamily
BsBEST3106_07400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BsBEST3106_07410	COG1120	ATPase activity
BsBEST3106_07420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3106_07430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3106_07440	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3106_07470	COG3866	Pectate lyase
BsBEST3106_07480	COG0471	metal ion transport
BsBEST3106_07490	COG3290	protein histidine kinase activity
BsBEST3106_07500	COG4565	transcriptional regulatory protein
BsBEST3106_07510	COG3181	Tripartite tricarboxylate transporter family receptor
BsBEST3106_07520	COG2851	Citrate transporter
BsBEST3106_07530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3106_07540	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BsBEST3106_07550	COG1254	Belongs to the acylphosphatase family
BsBEST3106_07560	COG2258	MOSC domain
BsBEST3106_07600	COG0024	Methionine aminopeptidase
BsBEST3106_07610	COG1263	PTS System
BsBEST3106_07610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3106_07620	COG1368	sulfuric ester hydrolase activity
BsBEST3106_07640	COG1115	amino acid carrier protein
BsBEST3106_07650	COG0531	amino acid
BsBEST3106_07680	COG0697	spore germination
BsBEST3106_07690	COG1263	PTS System
BsBEST3106_07690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3106_07700	COG0366	Alpha amylase catalytic
BsBEST3106_07710	COG2188	Transcriptional regulator
BsBEST3106_07720	COG0778	Nitroreductase
BsBEST3106_07730	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3106_07740	COG0693	protein deglycase activity
BsBEST3106_07750	COG2814	Major facilitator Superfamily
BsBEST3106_07760	COG4840	Belongs to the UPF0435 family
BsBEST3106_07770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3106_07780	COG4980	gas vesicle protein
BsBEST3106_07790	COG1295	ribonuclease BN
BsBEST3106_07800	COG0477	Major facilitator Superfamily
BsBEST3106_07810	COG0387	Pfam Sodium calcium exchanger
BsBEST3106_07830	COG0668	transmembrane transport
BsBEST3106_07840	COG0535	radical SAM domain protein
BsBEST3106_07860	COG0726	polysaccharide deacetylase
BsBEST3106_07870	COG2084	Dehydrogenase
BsBEST3106_07880	COG0598	Magnesium transport protein CorA
BsBEST3106_07890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3106_07900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3106_07920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3106_07930	COG4637	Psort location Cytoplasmic, score
BsBEST3106_07950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3106_07960	COG0022	dehydrogenase e1 component
BsBEST3106_07970	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3106_07980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3106_07990	COG3284	Transcriptional regulator
BsBEST3106_08010	COG1742	UPF0060 membrane protein
BsBEST3106_08060	COG4842	Belongs to the WXG100 family
BsBEST3106_08070	COG1486	melibiose metabolic process
BsBEST3106_08080	COG1737	Transcriptional regulator
BsBEST3106_08090	COG1263	PTS System
BsBEST3106_08090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3106_08100	COG1132	(ABC) transporter
BsBEST3106_08110	COG1132	(ABC) transporter
BsBEST3106_08120	COG2259	Doxx family
BsBEST3106_08130	COG2514	catechol 2,3-dioxygenase activity
BsBEST3106_08140	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3106_08140	COG4977	sequence-specific DNA binding
BsBEST3106_08150	COG2814	Major facilitator Superfamily
BsBEST3106_08160	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3106_08170	COG0673	inositol 2-dehydrogenase activity
BsBEST3106_08180	COG4585	Histidine kinase
BsBEST3106_08190	COG2197	response regulator
BsBEST3106_08200	COG1131	(ABC) transporter
BsBEST3106_08210	COG0842	Transport permease protein
BsBEST3106_08210	COG1511	domain protein
BsBEST3106_08220	COG0842	Transport permease protein
BsBEST3106_08230	COG1695	Transcriptional regulator
BsBEST3106_08240	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3106_08250	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BsBEST3106_08260	COG1309	transcriptional regulator
BsBEST3106_08270	COG2814	Major facilitator Superfamily
BsBEST3106_08280	COG2318	DinB family
BsBEST3106_08290	COG2814	Major facilitator Superfamily
BsBEST3106_08300	COG1846	Transcriptional regulator
BsBEST3106_08310	COG0392	lysyltransferase activity
BsBEST3106_08310	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BsBEST3106_08320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3106_08330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3106_08340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3106_08350	COG0384	phenazine biosynthesis protein PhzF
BsBEST3106_08360	COG0778	Nitroreductase
BsBEST3106_08380	COG1090	epimerase
BsBEST3106_08390	COG2137	regulation of response to DNA damage stimulus
BsBEST3106_08410	COG2814	Major facilitator Superfamily
BsBEST3106_08440	COG3103	Sh3 type 3 domain protein
BsBEST3106_08450	COG5658	integral membrane protein
BsBEST3106_08460	COG0596	Alpha beta hydrolase
BsBEST3106_08470	COG0463	Glycosyl transferase, family 2
BsBEST3106_08480	COG4485	Bacterial membrane protein, YfhO
BsBEST3106_08490	COG1988	membrane-bound metal-dependent
BsBEST3106_08500	COG1194	a g-specific adenine glycosylase
BsBEST3106_08520	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_08550	COG3557	Belongs to the UPF0374 family
BsBEST3106_08560	COG1132	(ABC) transporter
BsBEST3106_08570	COG4129	membrane
BsBEST3106_08580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3106_08590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BsBEST3106_08600	COG0735	belongs to the Fur family
BsBEST3106_08630	COG4326	sporulation control protein
BsBEST3106_08650	COG3340	Belongs to the peptidase S51 family
BsBEST3106_08660	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BsBEST3106_08670	COG0277	FAD linked oxidase domain protein
BsBEST3106_08690	COG0753	catalase activity
BsBEST3106_08700	COG1116	anion transmembrane transporter activity
BsBEST3106_08710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3106_08720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3106_08730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3106_08750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BsBEST3106_08770	COG1476	TRANSCRIPTIONal
BsBEST3106_08780	COG3382	B3 4 domain protein
BsBEST3106_08790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BsBEST3106_08810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BsBEST3106_08820	COG0789	Transcriptional regulator
BsBEST3106_08830	COG1664	Polymer-forming cytoskeletal
BsBEST3106_08840	COG1664	Polymer-forming cytoskeletal
BsBEST3106_08850	COG2766	serine protein kinase
BsBEST3106_08860	COG2718	Belongs to the UPF0229 family
BsBEST3106_08870	COG1846	Transcriptional regulator
BsBEST3106_08880	COG1566	PFAM secretion protein HlyD family protein
BsBEST3106_08890	COG2814	Major facilitator Superfamily
BsBEST3106_08900	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3106_08930	COG1725	Transcriptional regulator
BsBEST3106_08940	COG1131	(ABC) transporter
BsBEST3106_08950	COG1131	(ABC) transporter
BsBEST3106_08960	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3106_08970	COG1278	Cold shock
BsBEST3106_08980	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3106_08990	COG3706	GGDEF domain
BsBEST3106_09000	COG1823	symporter activity
BsBEST3106_09040	COG5577	PFAM Coat F domain
BsBEST3106_09050	COG4085	toxin activity
BsBEST3106_09050	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3106_09050	COG1525	nuclease
BsBEST3106_09060	COG3764	Sortase (surface protein transpeptidase)
BsBEST3106_09070	COG0564	pseudouridine synthase activity
BsBEST3106_09090	COG0517	IMP dehydrogenase activity
BsBEST3106_09100	COG0517	IMP dehydrogenase activity
BsBEST3106_09110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3106_09120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3106_09120	COG3153	acetyltransferase
BsBEST3106_09140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3106_09150	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BsBEST3106_09160	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BsBEST3106_09170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BsBEST3106_09180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BsBEST3106_09190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3106_09200	COG4585	Histidine kinase
BsBEST3106_09200	COG2203	Gaf domain
BsBEST3106_09210	COG2197	response regulator
BsBEST3106_09220	COG0431	NADPH-dependent FMN reductase
BsBEST3106_09250	COG0791	NLP P60 protein
BsBEST3106_09250	COG1388	LysM domain
BsBEST3106_09260	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3106_09270	COG0668	transmembrane transport
BsBEST3106_09280	COG2719	SpoVR family
BsBEST3106_09290	COG1785	Belongs to the alkaline phosphatase family
BsBEST3106_09300	COG0791	NLP P60 protein
BsBEST3106_09300	COG1388	LysM domain
BsBEST3106_09310	COG0583	DNA-binding transcription factor activity
BsBEST3106_09320	COG0372	Belongs to the citrate synthase family
BsBEST3106_09330	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_09340	COG0531	amino acid
BsBEST3106_09350	COG0733	neurotransmitter:sodium symporter activity
BsBEST3106_09360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3106_09370	COG0456	acetyltransferase
BsBEST3106_09400	COG1595	DNA-templated transcription, initiation
BsBEST3106_09410	COG0667	Aldo Keto reductase
BsBEST3106_09420	COG0204	Acyl-transferase
BsBEST3106_09430	COG1253	flavin adenine dinucleotide binding
BsBEST3106_09440	COG0789	Transcriptional regulator
BsBEST3106_09450	COG0436	Aminotransferase
BsBEST3106_09460	COG1253	flavin adenine dinucleotide binding
BsBEST3106_09470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3106_09480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3106_09490	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3106_09510	COG0668	transmembrane transport
BsBEST3106_09520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BsBEST3106_09530	COG0726	polysaccharide deacetylase
BsBEST3106_09540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3106_09550	COG1757	Na H antiporter
BsBEST3106_09560	COG0589	response to stress
BsBEST3106_09570	COG1132	(ABC) transporter
BsBEST3106_09580	COG1132	(ABC) transporter
BsBEST3106_09590	COG0702	epimerase
BsBEST3106_09620	COG0189	ligase activity
BsBEST3106_09630	COG0189	ligase activity
BsBEST3106_09640	COG4399	Belongs to the UPF0754 family
BsBEST3106_09650	COG3679	Belongs to the UPF0342 family
BsBEST3106_09660	COG4335	DNA alkylation repair
BsBEST3106_09670	COG0561	phosphatase activity
BsBEST3106_09680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3106_09690	COG0475	glutathione-regulated potassium exporter activity
BsBEST3106_09700	COG0490	domain, Protein
BsBEST3106_09720	COG1024	Enoyl-CoA hydratase
BsBEST3106_09740	COG4152	abc transporter atp-binding protein
BsBEST3106_09750	COG1668	transmembrane transport
BsBEST3106_09760	COG0420	3'-5' exonuclease activity
BsBEST3106_09770	COG4717	serine-type aminopeptidase activity
BsBEST3106_09780	COG3481	metal-dependent phosphohydrolase, HD sub domain
BsBEST3106_09800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3106_09830	COG1846	Transcriptional regulator
BsBEST3106_09840	COG4980	gas vesicle protein
BsBEST3106_09860	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BsBEST3106_09870	COG0537	adenosine 5'-monophosphoramidase activity
BsBEST3106_09880	COG1131	(ABC) transporter
BsBEST3106_09890	COG4473	ABC transporter
BsBEST3106_09910	COG1473	amidohydrolase
BsBEST3106_09920	COG1473	amidohydrolase
BsBEST3106_09930	COG3069	C4-dicarboxylate transmembrane transporter activity
BsBEST3106_09940	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3106_09950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3106_09960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BsBEST3106_09970	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BsBEST3106_09980	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BsBEST3106_09990	COG1309	transcriptional regulator
BsBEST3106_10000	COG1511	domain protein
BsBEST3106_10010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3106_10020	COG4377	Putative membrane peptidase family (DUF2324)
BsBEST3106_10040	COG1363	Peptidase, m42
BsBEST3106_10050	COG4405	Protein conserved in bacteria
BsBEST3106_10060	COG1301	dicarboxylic acid transport
BsBEST3106_10070	COG1234	tRNA 3'-trailer cleavage
BsBEST3106_10080	COG0095	Lipoate-protein ligase
BsBEST3106_10090	COG0702	epimerase
BsBEST3106_10100	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3106_10120	COG0501	Belongs to the peptidase M48B family
BsBEST3106_10140	COG0456	acetyltransferase
BsBEST3106_10150	COG0604	alcohol dehydrogenase
BsBEST3106_10160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3106_10170	COG0406	alpha-ribazole phosphatase activity
BsBEST3106_10180	COG0183	Belongs to the thiolase family
BsBEST3106_10190	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3106_10200	COG1268	BioY protein
BsBEST3106_10210	COG0840	transmembrane signaling receptor activity
BsBEST3106_10220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3106_10220	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3106_10230	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_10250	COG4903	ComK protein
BsBEST3106_10260	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_10280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3106_10310	COG0398	Pfam SNARE associated Golgi protein
BsBEST3106_10320	COG0681	Belongs to the peptidase S26 family
BsBEST3106_10330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3106_10340	COG1846	Transcriptional regulator
BsBEST3106_10350	COG0738	Major facilitator superfamily
BsBEST3106_10370	COG0673	inositol 2-dehydrogenase activity
BsBEST3106_10380	COG0561	phosphatase activity
BsBEST3106_10390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3106_10400	COG1609	Transcriptional regulator
BsBEST3106_10410	COG3180	Ammonia monooxygenase
BsBEST3106_10420	COG0477	Major facilitator Superfamily
BsBEST3106_10420	COG2814	Major facilitator Superfamily
BsBEST3106_10430	COG4533	DNA binding
BsBEST3106_10450	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BsBEST3106_10460	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BsBEST3106_10470	COG1074	ATP-dependent DNA helicase activity
BsBEST3106_10480	COG0420	3'-5' exonuclease activity
BsBEST3106_10490	COG0419	ATPase involved in DNA repair
BsBEST3106_10500	COG1403	HNH endonuclease
BsBEST3106_10580	COG0179	Fumarylacetoacetate (FAA) hydrolase
BsBEST3106_10600	COG1404	Belongs to the peptidase S8 family
BsBEST3106_10620	COG0367	asparagine synthase
BsBEST3106_10630	COG2318	DinB family
BsBEST3106_10640	COG1562	ergosterol biosynthetic process
BsBEST3106_10650	COG0534	Mate efflux family protein
BsBEST3106_10660	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3106_10660	COG2207	Transcriptional regulator
BsBEST3106_10670	COG1609	Transcriptional regulator
BsBEST3106_10680	COG0673	inositol 2-dehydrogenase activity
BsBEST3106_10690	COG2318	DinB family
BsBEST3106_10700	COG1279	arginine transmembrane transporter activity
BsBEST3106_10710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3106_10720	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3106_10730	COG2267	carboxylic ester hydrolase activity
BsBEST3106_10740	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3106_10750	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3106_10760	COG0175	sulfate reduction
BsBEST3106_10770	COG2045	Belongs to the ComB family
BsBEST3106_10780	COG1809	phosphosulfolactate synthase activity
BsBEST3106_10790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3106_10800	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3106_10810	COG2814	Major facilitator Superfamily
BsBEST3106_10820	COG0454	-acetyltransferase
BsBEST3106_10830	COG2153	protein acetylation
BsBEST3106_10840	COG0646	methionine synthase
BsBEST3106_10840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BsBEST3106_10850	COG1666	GTP binding
BsBEST3106_10860	COG2996	Protein conserved in bacteria
BsBEST3106_10900	COG1695	Transcriptional regulator
BsBEST3106_10930	COG3227	Zinc metalloprotease (Elastase)
BsBEST3106_10940	COG1307	EDD domain protein, DegV family
BsBEST3106_10950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3106_10980	COG0561	phosphatase activity
BsBEST3106_10990	COG1073	alpha beta
BsBEST3106_11000	COG2151	metal-sulfur cluster biosynthetic enzyme
BsBEST3106_11020	COG0277	FAD linked oxidase domain protein
BsBEST3106_11030	COG2271	Major facilitator Superfamily
BsBEST3106_11040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BsBEST3106_11050	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BsBEST3106_11070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3106_11080	COG0505	Belongs to the CarA family
BsBEST3106_11090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3106_11100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BsBEST3106_11130	COG2267	carboxylic ester hydrolase activity
BsBEST3106_11150	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3106_11180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3106_11190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3106_11200	COG5504	Zn-dependent protease
BsBEST3106_11210	COG0444	Belongs to the ABC transporter superfamily
BsBEST3106_11220	COG4608	Belongs to the ABC transporter superfamily
BsBEST3106_11250	COG0601	transmembrane transport
BsBEST3106_11260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3106_11280	COG0180	Tryptophanyl-tRNA synthetase
BsBEST3106_11290	COG4166	transmembrane transport
BsBEST3106_11300	COG0601	transmembrane transport
BsBEST3106_11310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3106_11320	COG0444	Belongs to the ABC transporter superfamily
BsBEST3106_11330	COG4608	Belongs to the ABC transporter superfamily
BsBEST3106_11340	COG2814	Major facilitator Superfamily
BsBEST3106_11350	COG0456	acetyltransferase
BsBEST3106_11360	COG1393	Belongs to the ArsC family
BsBEST3106_11370	COG0861	Integral membrane protein TerC family
BsBEST3106_11380	COG4862	establishment of competence for transformation
BsBEST3106_11390	COG1164	Oligoendopeptidase f
BsBEST3106_11410	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3106_11420	COG2346	COG2346, Truncated hemoglobins
BsBEST3106_11430	COG0741	lytic transglycosylase activity
BsBEST3106_11440	COG4116	CYTH
BsBEST3106_11460	COG2357	RelA SpoT domain protein
BsBEST3106_11470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3106_11480	COG0564	pseudouridine synthase activity
BsBEST3106_11490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BsBEST3106_11500	COG0569	domain protein
BsBEST3106_11500	COG0475	glutathione-regulated potassium exporter activity
BsBEST3106_11510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BsBEST3106_11520	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3106_11530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3106_11540	COG2104	thiamine diphosphate biosynthetic process
BsBEST3106_11550	COG2022	thiamine diphosphate biosynthetic process
BsBEST3106_11560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3106_11570	COG0351	phosphomethylpyrimidine kinase
BsBEST3106_11580	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BsBEST3106_11690	COG0210	DNA helicase
BsBEST3106_11710	COG2153	protein acetylation
BsBEST3106_11720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3106_11730	COG2382	esterase
BsBEST3106_11740	COG0626	cystathionine gamma-synthase activity
BsBEST3106_11750	COG0626	cystathionine gamma-synthase activity
BsBEST3106_11760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3106_11770	COG5505	Protein of unknown function (DUF819)
BsBEST3106_11830	COG3677	Transposase
BsBEST3106_11860	COG5484	DNA packaging
BsBEST3106_11870	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3106_11880	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_11900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3106_11900	COG3711	transcriptional antiterminator
BsBEST3106_11910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3106_11910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3106_11910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3106_11920	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3106_11940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3106_11960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3106_12000	COG0109	protoheme IX farnesyltransferase activity
BsBEST3106_12020	COG0726	polysaccharide deacetylase
BsBEST3106_12050	COG5504	Zn-dependent protease
BsBEST3106_12060	COG2205	protein histidine kinase activity
BsBEST3106_12080	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3106_12090	COG2427	Protein of unknown function (DUF1641)
BsBEST3106_12110	COG1051	belongs to the nudix hydrolase family
BsBEST3106_12130	COG2124	cytochrome p450
BsBEST3106_12140	COG1819	glycosyl
BsBEST3106_12160	COG1587	Uroporphyrinogen-III synthase
BsBEST3106_12170	COG0390	transport system, permease component
BsBEST3106_12180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3106_12190	COG0697	spore germination
BsBEST3106_12200	COG4297	protein containing double-stranded beta helix domain
BsBEST3106_12220	COG1252	NADH dehydrogenase
BsBEST3106_12230	COG1904	glucuronate isomerase
BsBEST3106_12240	COG2211	Major facilitator Superfamily
BsBEST3106_12250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BsBEST3106_12260	COG1063	alcohol dehydrogenase
BsBEST3106_12270	COG1312	Catalyzes the dehydration of D-mannonate
BsBEST3106_12280	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_12290	COG2271	Major facilitator Superfamily
BsBEST3106_12300	COG1609	Transcriptional regulator
BsBEST3106_12310	COG0246	Mannitol dehydrogenase
BsBEST3106_12320	COG2721	sulfolactate sulfo-lyase activity
BsBEST3106_12330	COG0730	response to heat
BsBEST3106_12340	COG2318	DinB family
BsBEST3106_12350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3106_12360	COG0457	Tetratricopeptide repeat
BsBEST3106_12380	COG2350	Protein conserved in bacteria
BsBEST3106_12390	COG1388	LysM domain
BsBEST3106_12390	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_12390	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_12410	COG4195	phage-related replication protein
BsBEST3106_12420	COG3546	catalase activity
BsBEST3106_12430	COG2856	Zn peptidase
BsBEST3106_12440	COG1396	sequence-specific DNA binding
BsBEST3106_12460	COG1522	sequence-specific DNA binding
BsBEST3106_12470	COG1484	DNA-dependent DNA replication
BsBEST3106_12510	COG1595	DNA-templated transcription, initiation
BsBEST3106_12520	COG3728	DNA packaging
BsBEST3106_12520	COG5484	DNA packaging
BsBEST3106_12530	COG1783	phage Terminase large subunit
BsBEST3106_12540	COG5518	Phage portal protein
BsBEST3106_12550	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3106_12560	COG4653	Phage capsid family
BsBEST3106_12660	COG5412	phage tail tape measure protein
BsBEST3106_12660	COG3953	SLT domain
BsBEST3106_12670	COG1652	LysM domain
BsBEST3106_12680	COG4193	domain, Protein
BsBEST3106_12700	COG3628	GPW Gp25 family protein
BsBEST3106_12710	COG3299	homolog of phage Mu protein gp47
BsBEST3106_12720	COG3778	Protein conserved in bacteria
BsBEST3106_12800	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_12800	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_12830	COG0306	phosphate transporter
BsBEST3106_12840	COG1392	Phosphate transport regulator
BsBEST3106_12850	COG0531	amino acid
BsBEST3106_12860	COG0346	lactoylglutathione lyase activity
BsBEST3106_12880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3106_12890	COG0463	Glycosyl transferase, family 2
BsBEST3106_12910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3106_12920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3106_12930	COG2362	D-Aminopeptidase
BsBEST3106_12940	COG0601	transmembrane transport
BsBEST3106_12950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3106_12960	COG0444	Belongs to the ABC transporter superfamily
BsBEST3106_12970	COG4166	transmembrane transport
BsBEST3106_12980	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3106_12990	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3106_13000	COG0791	NLP P60 protein
BsBEST3106_13010	COG4608	Belongs to the ABC transporter superfamily
BsBEST3106_13020	COG2706	6-phosphogluconolactonase activity
BsBEST3106_13030	COG1834	amidinotransferase
BsBEST3106_13040	COG1607	acyl-coa hydrolase
BsBEST3106_13050	COG1017	nitric oxide dioxygenase activity
BsBEST3106_13050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BsBEST3106_13070	COG2323	membrane
BsBEST3106_13080	COG2318	DinB family
BsBEST3106_13090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3106_13100	COG2076	Multidrug Resistance protein
BsBEST3106_13110	COG2076	Multidrug Resistance protein
BsBEST3106_13120	COG0788	formyltetrahydrofolate deformylase activity
BsBEST3106_13130	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3106_13140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BsBEST3106_13150	COG1764	response to oxidative stress
BsBEST3106_13160	COG1846	Transcriptional regulator
BsBEST3106_13170	COG1764	response to oxidative stress
BsBEST3106_13190	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3106_13200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3106_13210	COG1404	Belongs to the peptidase S8 family
BsBEST3106_13220	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3106_13230	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3106_13240	COG1122	ATPase activity
BsBEST3106_13250	COG4721	ABC-type cobalt transport system, permease component
BsBEST3106_13270	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_13280	COG3850	Histidine kinase
BsBEST3106_13280	COG5002	protein histidine kinase activity
BsBEST3106_13290	COG3212	peptidase
BsBEST3106_13300	COG3212	peptidase
BsBEST3106_13330	COG2239	Acts as a magnesium transporter
BsBEST3106_13340	COG0789	Transcriptional regulator
BsBEST3106_13370	COG1846	Transcriptional regulator
BsBEST3106_13380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3106_13390	COG0726	polysaccharide deacetylase
BsBEST3106_13400	COG1408	metallophosphoesterase
BsBEST3106_13420	COG0463	Glycosyl transferase, family 2
BsBEST3106_13430	COG3285	dna ligase
BsBEST3106_13430	COG1793	dna ligase
BsBEST3106_13440	COG1793	dna ligase
BsBEST3106_13440	COG3285	dna ligase
BsBEST3106_13450	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BsBEST3106_13460	COG3300	MHYT domain
BsBEST3106_13460	COG5001	Diguanylate cyclase
BsBEST3106_13470	COG0586	Pfam SNARE associated Golgi protein
BsBEST3106_13480	COG0861	Integral membrane protein TerC family
BsBEST3106_13490	COG1191	sigma factor activity
BsBEST3106_13530	COG0501	Belongs to the peptidase M48B family
BsBEST3106_13540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3106_13570	COG3594	Acyltransferase
BsBEST3106_13580	COG5002	protein histidine kinase activity
BsBEST3106_13590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3106_13610	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BsBEST3106_13620	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BsBEST3106_13630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3106_13640	COG0436	Aminotransferase
BsBEST3106_13650	COG1850	ribulose-bisphosphate carboxylase activity
BsBEST3106_13660	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BsBEST3106_13670	COG0235	Class ii aldolase
BsBEST3106_13680	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BsBEST3106_13690	COG3339	Conserved Protein
BsBEST3106_13720	COG3852	Histidine kinase
BsBEST3106_13730	COG1846	Transcriptional regulator
BsBEST3106_13740	COG1360	Flagellar Motor Protein
BsBEST3106_13750	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3106_13760	COG0542	response to heat
BsBEST3106_13770	COG3949	Membrane
BsBEST3106_13780	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BsBEST3106_13790	COG0720	synthase
BsBEST3106_13800	COG0602	queuosine metabolic process
BsBEST3106_13810	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BsBEST3106_13820	COG1733	regulation of RNA biosynthetic process
BsBEST3106_13830	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_13840	COG4641	Protein conserved in bacteria
BsBEST3106_13840	COG1388	LysM domain
BsBEST3106_13850	COG1388	LysM domain
BsBEST3106_13860	COG3858	chitin binding
BsBEST3106_13870	COG3858	chitin binding
BsBEST3106_13890	COG4873	Protein conserved in bacteria
BsBEST3106_13910	COG3773	Cell wall hydrolase
BsBEST3106_13920	COG2244	polysaccharide biosynthetic process
BsBEST3106_13930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_13940	COG2217	Heavy metal translocating P-type atpase
BsBEST3106_13960	COG0006	proline dipeptidase activity
BsBEST3106_13980	COG1609	Transcriptional regulator
BsBEST3106_13990	COG3711	transcriptional antiterminator
BsBEST3106_14000	COG1263	PTS System
BsBEST3106_14000	COG2190	(PTS) system
BsBEST3106_14000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3106_14010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3106_14020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BsBEST3106_14040	COG1533	DNA photolyase activity
BsBEST3106_14050	COG0456	acetyltransferase
BsBEST3106_14060	COG0840	transmembrane signaling receptor activity
BsBEST3106_14070	COG2084	Dehydrogenase
BsBEST3106_14080	COG2340	Cysteine-rich secretory protein family
BsBEST3106_14090	COG0768	penicillin binding
BsBEST3106_14100	COG4191	Histidine kinase
BsBEST3106_14110	COG0436	Aminotransferase
BsBEST3106_14130	COG0784	Response regulator, receiver
BsBEST3106_14130	COG0835	chemotaxis
BsBEST3106_14150	COG2814	Major facilitator Superfamily
BsBEST3106_14160	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3106_14170	COG1408	metallophosphoesterase
BsBEST3106_14180	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_14190	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_14200	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_14220	COG2200	EAL domain
BsBEST3106_14230	COG4703	Protein of unknown function (DUF1797)
BsBEST3106_14240	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BsBEST3106_14260	COG0517	IMP dehydrogenase activity
BsBEST3106_14270	COG0583	DNA-binding transcription factor activity
BsBEST3106_14280	COG0716	FMN binding
BsBEST3106_14300	COG0716	FMN binding
BsBEST3106_14310	COG2171	N-acyltransferase activity
BsBEST3106_14320	COG1473	amidohydrolase
BsBEST3106_14340	COG0668	transmembrane transport
BsBEST3106_14350	COG0450	alkyl hydroperoxide reductase
BsBEST3106_14360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_14390	COG0746	molybdenum cofactor guanylyltransferase activity
BsBEST3106_14400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3106_14410	COG0303	'Molybdopterin
BsBEST3106_14420	COG1763	Mo-molybdopterin cofactor biosynthetic process
BsBEST3106_14430	COG0314	molybdopterin synthase activity
BsBEST3106_14440	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BsBEST3106_14450	COG1132	(ABC) transporter
BsBEST3106_14460	COG1132	(ABC) transporter
BsBEST3106_14480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3106_14490	COG1136	(ABC) transporter
BsBEST3106_14500	COG0577	efflux transmembrane transporter activity
BsBEST3106_14510	COG1349	DNA-binding transcription factor activity
BsBEST3106_14520	COG1105	Belongs to the carbohydrate kinase PfkB family
BsBEST3106_14530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3106_14530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3106_14530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3106_14540	COG0681	Belongs to the peptidase S26 family
BsBEST3106_14560	COG0488	(ABC) transporter
BsBEST3106_14570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3106_14580	COG2309	aminopeptidase activity
BsBEST3106_14600	COG1077	Cell shape determining protein MreB Mrl
BsBEST3106_14610	COG2002	toxin-antitoxin pair type II binding
BsBEST3106_14620	COG3852	Histidine kinase
BsBEST3106_14630	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BsBEST3106_14630	COG2105	PFAM AIG2 family protein
BsBEST3106_14640	COG0569	domain protein
BsBEST3106_14650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3106_14660	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3106_14670	COG5503	Protein of unknown function (DUF1447)
BsBEST3106_14680	COG0561	phosphatase activity
BsBEST3106_14690	COG0242	peptide deformylase activity
BsBEST3106_14710	COG0497	DNA recombination
BsBEST3106_14720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3106_14730	COG0022	dehydrogenase e1 component
BsBEST3106_14740	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3106_14750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3106_14760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_14770	COG1982	Orn Lys Arg decarboxylase major
BsBEST3106_14780	COG4476	Belongs to the UPF0223 family
BsBEST3106_14790	COG4493	Belongs to the UPF0637 family
BsBEST3106_14810	COG0483	inositol monophosphate 1-phosphatase activity
BsBEST3106_14830	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BsBEST3106_14870	COG1595	DNA-templated transcription, initiation
BsBEST3106_14910	COG1217	gtp-binding protein TYPA
BsBEST3106_14930	COG4896	Protein conserved in bacteria
BsBEST3106_14950	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BsBEST3106_14960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3106_14970	COG2066	Belongs to the glutaminase family
BsBEST3106_14980	COG4838	Belongs to the UPF0358 family
BsBEST3106_15000	COG0772	Belongs to the SEDS family
BsBEST3106_15010	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BsBEST3106_15020	COG1612	heme a metabolic process
BsBEST3106_15030	COG0109	protoheme IX farnesyltransferase activity
BsBEST3106_15040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3106_15040	COG2010	Cytochrome c
BsBEST3106_15050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3106_15060	COG1845	cytochrome c oxidase, subunit III
BsBEST3106_15070	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3106_15080	COG3336	cytochrome c oxidase
BsBEST3106_15100	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BsBEST3106_15110	COG2340	Cysteine-rich secretory protein family
BsBEST3106_15140	COG3679	Belongs to the UPF0342 family
BsBEST3106_15150	COG4471	UPF0298 protein
BsBEST3106_15160	COG0742	ribosomal rna small subunit methyltransferase
BsBEST3106_15170	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BsBEST3106_15180	COG3314	Sporulation integral membrane protein YlbJ
BsBEST3106_15190	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3106_15200	COG3480	Lon protease (S16) C-terminal proteolytic domain
BsBEST3106_15210	COG1323	Belongs to the UPF0348 family
BsBEST3106_15230	COG1399	metal-binding, possibly nucleic acid-binding protein
BsBEST3106_15260	COG0454	-acetyltransferase
BsBEST3106_15270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3106_15280	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BsBEST3106_15290	COG2001	Belongs to the MraZ family
BsBEST3106_15300	COG0275	rRNA processing
BsBEST3106_15310	COG4839	cell division protein FtsL
BsBEST3106_15320	COG0768	penicillin binding
BsBEST3106_15330	COG0768	penicillin binding
BsBEST3106_15340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BsBEST3106_15350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3106_15360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3106_15370	COG0772	Belongs to the SEDS family
BsBEST3106_15380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3106_15390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BsBEST3106_15400	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BsBEST3106_15410	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3106_15420	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3106_15430	COG3856	small basic protein
BsBEST3106_15440	COG0849	cell division
BsBEST3106_15450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BsBEST3106_15460	COG1404	Belongs to the peptidase S8 family
BsBEST3106_15460	COG4412	M6 family metalloprotease domain protein
BsBEST3106_15480	COG1191	sigma factor activity
BsBEST3106_15490	COG1191	sigma factor activity
BsBEST3106_15500	COG1119	ATPase activity
BsBEST3106_15510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3106_15520	COG1873	PFAM PRC-barrel domain
BsBEST3106_15530	COG1496	oxidoreductase activity
BsBEST3106_15540	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BsBEST3106_15550	COG1799	cell septum assembly
BsBEST3106_15560	COG0762	integral membrane protein
BsBEST3106_15570	COG2302	S4 RNA-binding domain
BsBEST3106_15580	COG3599	regulation of cell shape
BsBEST3106_15590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BsBEST3106_15600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3106_15610	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BsBEST3106_15620	COG0564	pseudouridine synthase activity
BsBEST3106_15630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BsBEST3106_15640	COG2233	PERMEase
BsBEST3106_15650	COG0540	Belongs to the ATCase OTCase family
BsBEST3106_15660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3106_15670	COG0505	Belongs to the CarA family
BsBEST3106_15680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3106_15690	COG0543	2 iron, 2 sulfur cluster binding
BsBEST3106_15700	COG0167	dihydroorotate dehydrogenase activity
BsBEST3106_15710	COG0284	orotidine-5'-phosphate decarboxylase activity
BsBEST3106_15720	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BsBEST3106_15730	COG0175	sulfate reduction
BsBEST3106_15740	COG0306	phosphate transporter
BsBEST3106_15750	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3106_15760	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3106_15770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3106_15780	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BsBEST3106_15790	COG1648	precorrin-2 dehydrogenase activity
BsBEST3106_15800	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BsBEST3106_15810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3106_15820	COG1561	YicC-like family, N-terminal region
BsBEST3106_15840	COG0194	GDP metabolic process
BsBEST3106_15850	COG1758	RNA polymerase activity
BsBEST3106_15860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3106_15870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3106_15880	COG0242	peptide deformylase activity
BsBEST3106_15890	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BsBEST3106_15900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3106_15900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BsBEST3106_15910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BsBEST3106_15920	COG0631	protein serine/threonine phosphatase activity
BsBEST3106_15930	COG0515	serine threonine protein kinase
BsBEST3106_15930	COG2815	serine threonine protein kinase
BsBEST3106_15940	COG1162	GTPase activity
BsBEST3106_15950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BsBEST3106_15960	COG1564	THIamine pyrophosphokinase
BsBEST3106_15970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BsBEST3106_15980	COG1302	Protein conserved in bacteria
BsBEST3106_15990	COG1461	Dihydroxyacetone kinase
BsBEST3106_16000	COG1760	l-serine dehydratase
BsBEST3106_16010	COG1760	l-serine dehydratase
BsBEST3106_16020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BsBEST3106_16030	COG1349	DNA-binding transcription factor activity
BsBEST3106_16030	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3106_16040	COG0416	fatty acid biosynthetic process
BsBEST3106_16050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3106_16060	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_16080	COG0571	ribonuclease III activity
BsBEST3106_16090	COG1196	nuclear chromosome segregation
BsBEST3106_16100	COG0552	protein localization to endoplasmic reticulum
BsBEST3106_16120	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BsBEST3106_16130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BsBEST3106_16140	COG0228	four-way junction DNA binding
BsBEST3106_16150	COG1837	Belongs to the UPF0109 family
BsBEST3106_16170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BsBEST3106_16180	COG0336	Belongs to the RNA methyltransferase TrmD family
BsBEST3106_16190	COG0335	large ribosomal subunit rRNA binding
BsBEST3106_16200	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3106_16210	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3106_16230	COG2257	FlhB HrpN YscU SpaS Family
BsBEST3106_16240	COG0045	succinate-CoA ligase (ADP-forming) activity
BsBEST3106_16250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BsBEST3106_16260	COG0758	DNA mediated transformation
BsBEST3106_16270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3106_16280	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BsBEST3106_16290	COG4974	Belongs to the 'phage' integrase family
BsBEST3106_16300	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BsBEST3106_16310	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BsBEST3106_16320	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3106_16330	COG1815	bacterial-type flagellum-dependent cell motility
BsBEST3106_16340	COG1558	bacterial-type flagellum-dependent cell motility
BsBEST3106_16350	COG1677	Flagellar hook-basal body complex protein FliE
BsBEST3106_16360	COG1766	The M ring may be actively involved in energy transduction
BsBEST3106_16370	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3106_16380	COG1317	bacterial-type flagellum organization
BsBEST3106_16390	COG1157	protein secretion by the type III secretion system
BsBEST3106_16400	COG2882	bacterial-type flagellum organization
BsBEST3106_16410	COG3334	PFAM MgtE intracellular
BsBEST3106_16420	COG3144	bacterial-type flagellum assembly
BsBEST3106_16430	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BsBEST3106_16440	COG4786	Flagellar basal body rod
BsBEST3106_16450	COG1582	Flagellar protein (FlbD)
BsBEST3106_16460	COG1580	Controls the rotational direction of flagella during chemotaxis
BsBEST3106_16470	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3106_16480	COG1776	CheC inhibitor of MCP methylation
BsBEST3106_16480	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3106_16490	COG2201	protein-glutamate methylesterase activity
BsBEST3106_16500	COG3190	flagellar
BsBEST3106_16510	COG1338	Plays a role in the flagellum-specific transport system
BsBEST3106_16520	COG1987	bacterial-type flagellum assembly
BsBEST3106_16530	COG1684	flagellar biosynthetic protein fliR
BsBEST3106_16540	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3106_16550	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3106_16560	COG1419	protein localization to endoplasmic reticulum
BsBEST3106_16570	COG0455	bacterial-type flagellum organization
BsBEST3106_16580	COG2201	protein-glutamate methylesterase activity
BsBEST3106_16590	COG0643	Histidine kinase
BsBEST3106_16590	COG2198	Histidine kinase
BsBEST3106_16600	COG0835	chemotaxis
BsBEST3106_16610	COG1776	CheC inhibitor of MCP methylation
BsBEST3106_16620	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BsBEST3106_16630	COG1191	sigma factor activity
BsBEST3106_16650	COG0052	Belongs to the universal ribosomal protein uS2 family
BsBEST3106_16660	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BsBEST3106_16670	COG0528	UMP kinase activity
BsBEST3106_16680	COG0233	cytoplasmic translational termination
BsBEST3106_16690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BsBEST3106_16700	COG4589	Belongs to the CDS family
BsBEST3106_16710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BsBEST3106_16720	COG0750	zinc metalloprotease
BsBEST3106_16730	COG0442	prolyl-tRNA aminoacylation
BsBEST3106_16740	COG2176	DNA-directed DNA polymerase activity
BsBEST3106_16750	COG0779	Required for maturation of 30S ribosomal subunits
BsBEST3106_16760	COG0195	Participates in both transcription termination and antitermination
BsBEST3106_16770	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BsBEST3106_16780	COG1358	cellular component organization or biogenesis
BsBEST3106_16790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BsBEST3106_16800	COG1550	Protein conserved in bacteria
BsBEST3106_16810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BsBEST3106_16820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BsBEST3106_16830	COG0196	riboflavin kinase activity
BsBEST3106_16840	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BsBEST3106_16850	COG1185	polyribonucleotide nucleotidyltransferase activity
BsBEST3106_16860	COG0726	polysaccharide deacetylase
BsBEST3106_16870	COG0612	Peptidase, M16
BsBEST3106_16880	COG1873	PFAM PRC-barrel domain
BsBEST3106_16890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3106_16900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3106_16910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BsBEST3106_16920	COG0527	aspartate kinase activity
BsBEST3106_16930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3106_16940	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3106_16950	COG0740	serine-type endopeptidase activity
BsBEST3106_16970	COG4980	gas vesicle protein
BsBEST3106_16970	COG1674	ftsk spoiiie
BsBEST3106_16980	COG2188	Transcriptional regulator
BsBEST3106_16990	COG2814	Major facilitator Superfamily
BsBEST3106_17000	COG0612	Peptidase, M16
BsBEST3106_17010	COG0612	Peptidase, M16
BsBEST3106_17020	COG0300	oxidoreductase activity
BsBEST3106_17060	COG1426	Protein conserved in bacteria
BsBEST3106_17070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BsBEST3106_17080	COG1058	Belongs to the CinA family
BsBEST3106_17080	COG1546	Belongs to the CinA family
BsBEST3106_17090	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BsBEST3106_17100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3106_17110	COG1418	mRNA catabolic process
BsBEST3106_17120	COG1692	metallophosphoesterase
BsBEST3106_17130	COG2359	stage V sporulation protein S
BsBEST3106_17140	COG1063	alcohol dehydrogenase
BsBEST3106_17150	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3106_17160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3106_17170	COG4550	Control of competence regulator ComK, YlbF/YmcA
BsBEST3106_17190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BsBEST3106_17200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BsBEST3106_17230	COG3226	Transcriptional regulator
BsBEST3106_17240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3106_17260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3106_17270	COG3321	synthase
BsBEST3106_17280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3106_17280	COG2070	2-Nitropropane dioxygenase
BsBEST3106_17290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3106_17300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3106_17310	COG3425	synthase
BsBEST3106_17320	COG1024	Enoyl-CoA hydratase
BsBEST3106_17330	COG1024	Enoyl-CoA hydratase
BsBEST3106_17340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_17340	COG3321	synthase
BsBEST3106_17340	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_17340	COG0300	oxidoreductase activity
BsBEST3106_17340	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3106_17350	COG4221	oxidoreductase activity
BsBEST3106_17350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3106_17350	COG0300	oxidoreductase activity
BsBEST3106_17350	COG3321	synthase
BsBEST3106_17360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_17360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3106_17360	COG3321	synthase
BsBEST3106_17360	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_17360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3106_17370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_17370	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_17370	COG4221	oxidoreductase activity
BsBEST3106_17370	COG3321	synthase
BsBEST3106_17380	COG3321	synthase
BsBEST3106_17380	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_17380	COG4221	oxidoreductase activity
BsBEST3106_17380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_17390	COG3321	synthase
BsBEST3106_17390	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3106_17390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3106_17390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BsBEST3106_17400	COG2124	cytochrome p450
BsBEST3106_17420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3106_17430	COG1404	Belongs to the peptidase S8 family
BsBEST3106_17440	COG4195	phage-related replication protein
BsBEST3106_17450	COG1764	response to oxidative stress
BsBEST3106_17460	COG2076	Multidrug Resistance protein
BsBEST3106_17470	COG2076	Multidrug Resistance protein
BsBEST3106_17500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BsBEST3106_17510	COG1923	regulation of RNA biosynthetic process
BsBEST3106_17540	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3106_17550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3106_17560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3106_17570	COG4112	unkown
BsBEST3106_17580	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_17590	COG0464	growth
BsBEST3106_17600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BsBEST3106_17610	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BsBEST3106_17620	COG0789	Transcriptional regulator
BsBEST3106_17630	COG0174	glutamine synthetase
BsBEST3106_17670	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3106_17690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3106_17740	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3106_17750	COG2211	Major facilitator Superfamily
BsBEST3106_17760	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3106_17770	COG1940	carbohydrate kinase activity
BsBEST3106_17780	COG2115	Belongs to the xylose isomerase family
BsBEST3106_17790	COG1070	Carbohydrate kinase
BsBEST3106_17800	COG1525	nuclease
BsBEST3106_17810	COG2814	Major facilitator Superfamily
BsBEST3106_17820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3106_17840	COG0756	dUTP diphosphatase activity
BsBEST3106_17890	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3106_17940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3106_17960	COG3832	glyoxalase III activity
BsBEST3106_17980	COG0697	spore germination
BsBEST3106_17990	COG0531	amino acid
BsBEST3106_18050	COG4195	phage-related replication protein
BsBEST3106_18070	COG0346	lactoylglutathione lyase activity
BsBEST3106_18080	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BsBEST3106_18090	COG1388	LysM domain
BsBEST3106_18100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3106_18110	COG4224	UPF0291 protein
BsBEST3106_18120	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BsBEST3106_18140	COG3763	UPF0154 protein
BsBEST3106_18160	COG0785	Cytochrome C biogenesis protein
BsBEST3106_18170	COG2201	protein-glutamate methylesterase activity
BsBEST3106_18180	COG4846	Membrane protein involved in cytochrome C biogenesis
BsBEST3106_18200	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3106_18230	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BsBEST3106_18240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_18280	COG0824	Thioesterase
BsBEST3106_18300	COG4841	protein insertion into membrane
BsBEST3106_18310	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BsBEST3106_18320	COG1832	CoA-binding protein
BsBEST3106_18330	COG0187	DNA topoisomerase II activity
BsBEST3106_18340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3106_18360	COG1115	amino acid carrier protein
BsBEST3106_18370	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BsBEST3106_18390	COG5520	Belongs to the glycosyl hydrolase 30 family
BsBEST3106_18400	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3106_18410	COG2246	polysaccharide biosynthetic process
BsBEST3106_18420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3106_18430	COG0586	Pfam SNARE associated Golgi protein
BsBEST3106_18440	COG2404	hydrolase activity, acting on ester bonds
BsBEST3106_18450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3106_18460	COG1024	Enoyl-CoA hydratase
BsBEST3106_18470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3106_18480	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3106_18490	COG0439	Biotin carboxylase
BsBEST3106_18500	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3106_18510	COG1960	acyl-CoA dehydrogenase activity
BsBEST3106_18530	COG1649	PFAM Uncharacterised BCR, COG1649
BsBEST3106_18550	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3106_18550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_18560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_18570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_18580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_18590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_18600	COG2027	D-alanyl-D-alanine carboxypeptidase
BsBEST3106_18610	COG2017	converts alpha-aldose to the beta-anomer
BsBEST3106_18620	COG0534	Mate efflux family protein
BsBEST3106_18640	COG0582	viral genome integration into host DNA
BsBEST3106_18650	COG0166	Belongs to the GPI family
BsBEST3106_18660	COG0405	Gamma-glutamyltransferase
BsBEST3106_18670	COG0583	DNA-binding transcription factor activity
BsBEST3106_18680	COG0604	alcohol dehydrogenase
BsBEST3106_18690	COG0493	'glutamate synthase
BsBEST3106_18700	COG0067	glutamate synthase
BsBEST3106_18700	COG0069	glutamate synthase activity
BsBEST3106_18700	COG0070	glutamate synthase
BsBEST3106_18710	COG0583	DNA-binding transcription factor activity
BsBEST3106_18720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3106_18730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3106_18750	COG0300	oxidoreductase activity
BsBEST3106_18760	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3106_18780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3106_18790	COG2814	Major facilitator Superfamily
BsBEST3106_18800	COG1070	Carbohydrate kinase
BsBEST3106_18810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3106_18820	COG0243	molybdopterin cofactor binding
BsBEST3106_18870	COG5278	phosphoserine phosphatase activity
BsBEST3106_18870	COG0840	transmembrane signaling receptor activity
BsBEST3106_18880	COG2368	4-hydroxyphenylacetate
BsBEST3106_18890	COG4305	rare lipoprotein A
BsBEST3106_18900	COG3619	membrane
BsBEST3106_18910	COG3866	Pectate lyase
BsBEST3106_18920	COG2135	peptidase activity
BsBEST3106_18940	COG2140	Oxalate decarboxylase
BsBEST3106_18960	COG0456	acetyltransferase
BsBEST3106_18990	COG2720	vancomycin resistance protein
BsBEST3106_19010	COG3655	Transcriptional regulator
BsBEST3106_19020	COG3739	integral membrane protein
BsBEST3106_19030	COG0583	DNA-binding transcription factor activity
BsBEST3106_19040	COG0697	spore germination
BsBEST3106_19060	COG0693	protein deglycase activity
BsBEST3106_19070	COG2367	Beta-lactamase
BsBEST3106_19110	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3106_19110	COG3848	Pyruvate phosphate dikinase
BsBEST3106_19120	COG0726	polysaccharide deacetylase
BsBEST3106_19130	COG2314	TM2 domain
BsBEST3106_19140	COG1396	sequence-specific DNA binding
BsBEST3106_19170	COG2135	peptidase activity
BsBEST3106_19230	COG0457	Tetratricopeptide repeat
BsBEST3106_19250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3106_19260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3106_19290	COG5290	Psort location Cytoplasmic, score
BsBEST3106_19340	COG5444	nuclease activity
BsBEST3106_19350	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3106_19360	COG1231	oxidoreductase activity
BsBEST3106_19370	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3106_19380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3106_19390	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3106_19390	COG2207	Transcriptional regulator
BsBEST3106_19400	COG0456	acetyltransferase
BsBEST3106_19410	COG1309	transcriptional regulator
BsBEST3106_19420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3106_19430	COG3708	Transcriptional regulator
BsBEST3106_19440	COG2378	regulation of single-species biofilm formation
BsBEST3106_19460	COG0640	Transcriptional regulator
BsBEST3106_19470	COG0741	lytic transglycosylase activity
BsBEST3106_19480	COG2322	membrane
BsBEST3106_19510	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3106_19520	COG3239	Fatty acid desaturase
BsBEST3106_19530	COG4585	Histidine kinase
BsBEST3106_19540	COG2197	response regulator
BsBEST3106_19550	COG1388	LysM domain
BsBEST3106_19550	COG3584	3D domain protein
BsBEST3106_19560	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3106_19570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3106_19580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3106_19610	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3106_19660	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_19670	COG1657	PFAM Prenyltransferase squalene oxidase
BsBEST3106_19680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3106_19690	COG0733	neurotransmitter:sodium symporter activity
BsBEST3106_19700	COG0385	Bile acid
BsBEST3106_19710	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3106_19720	COG0567	Dehydrogenase, E1 component
BsBEST3106_19730	COG4548	von Willebrand factor, type A
BsBEST3106_19740	COG0714	Associated with various cellular activities
BsBEST3106_19750	COG2032	superoxide dismutase activity
BsBEST3106_19760	COG0791	NLP P60 protein
BsBEST3106_19760	COG1388	LysM domain
BsBEST3106_19770	COG1819	glycosyl
BsBEST3106_19780	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3106_19790	COG0534	Mate efflux family protein
BsBEST3106_19800	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3106_19810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3106_19820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3106_19840	COG2962	Rard protein
BsBEST3106_19870	COG2610	gluconate transmembrane transporter activity
BsBEST3106_19880	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3106_19890	COG1733	regulation of RNA biosynthetic process
BsBEST3106_19900	COG0778	Nitroreductase
BsBEST3106_19910	COG0400	carboxylic ester hydrolase activity
BsBEST3106_19920	COG0346	lactoylglutathione lyase activity
BsBEST3106_19940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3106_19950	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_19950	COG0793	Belongs to the peptidase S41A family
BsBEST3106_19960	COG2226	methyltransferase
BsBEST3106_19980	COG1876	peptidase activity
BsBEST3106_19990	COG0813	purine-nucleoside phosphorylase activity
BsBEST3106_20020	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3106_20060	COG4479	Belongs to the UPF0346 family
BsBEST3106_20080	COG1509	lysine 2,3-aminomutase activity
BsBEST3106_20090	COG0456	acetyltransferase
BsBEST3106_20100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3106_20110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3106_20120	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3106_20130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3106_20160	COG0456	acetyltransferase
BsBEST3106_20170	COG0463	Glycosyl transferase, family 2
BsBEST3106_20200	COG4641	Protein conserved in bacteria
BsBEST3106_20210	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BsBEST3106_20220	COG1086	Polysaccharide biosynthesis protein
BsBEST3106_20240	COG3331	DNA recombination
BsBEST3106_20330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3106_20390	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BsBEST3106_20400	COG0756	dUTP diphosphatase activity
BsBEST3106_20410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_20420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3106_20440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3106_20460	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3106_20460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3106_20470	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3106_20470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3106_20480	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3106_20660	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3106_20680	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BsBEST3106_20690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3106_20740	COG3584	3D domain protein
BsBEST3106_20750	COG0587	DNA-directed DNA polymerase activity
BsBEST3106_20760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3106_20770	COG0358	DNA primase activity
BsBEST3106_20780	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3106_20800	COG2887	Belongs to the helicase family. UvrD subfamily
BsBEST3106_20860	COG3420	alginic acid biosynthetic process
BsBEST3106_20860	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3106_20870	COG4195	phage-related replication protein
BsBEST3106_20900	COG2135	peptidase activity
BsBEST3106_20910	COG1793	dna ligase
BsBEST3106_21010	COG4474	Belongs to the UPF0398 family
BsBEST3106_21030	COG1388	LysM domain
BsBEST3106_21070	COG3645	SOS response
BsBEST3106_21070	COG3646	Phage regulatory protein
BsBEST3106_21180	COG3655	Transcriptional regulator
BsBEST3106_21210	COG0582	viral genome integration into host DNA
BsBEST3106_21370	COG3655	Transcriptional regulator
BsBEST3106_21440	COG1395	domain, Protein
BsBEST3106_21480	COG0776	regulation of translation
BsBEST3106_21540	COG4373	Mu-like prophage FluMu protein gp28
BsBEST3106_21740	COG0582	viral genome integration into host DNA
BsBEST3106_21800	COG0739	heme binding
BsBEST3106_21800	COG0741	lytic transglycosylase activity
BsBEST3106_21800	COG1196	nuclear chromosome segregation
BsBEST3106_21820	COG2433	Pfam Transposase IS66
BsBEST3106_21840	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3106_21840	COG4632	Exopolysaccharide biosynthesis protein
BsBEST3106_21870	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_21900	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3106_21910	COG0463	Glycosyl transferase, family 2
BsBEST3106_21920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_21930	COG2274	protein secretion by the type I secretion system
BsBEST3106_21930	COG3271	cysteine-type peptidase activity
BsBEST3106_21960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3106_22010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3106_22040	COG5444	nuclease activity
BsBEST3106_22050	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3106_22070	COG1525	nuclease
BsBEST3106_22090	COG2746	aminoglycoside 3-N-acetyltransferase activity
BsBEST3106_22140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3106_22150	COG1086	Polysaccharide biosynthesis protein
BsBEST3106_22160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3106_22170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3106_22180	COG1846	Transcriptional regulator
BsBEST3106_22190	COG0534	Mate efflux family protein
BsBEST3106_22210	COG4698	Protein conserved in bacteria
BsBEST3106_22220	COG2755	lipolytic protein G-D-S-L family
BsBEST3106_22230	COG1999	signal sequence binding
BsBEST3106_22250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BsBEST3106_22260	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3106_22270	COG1272	protein, Hemolysin III
BsBEST3106_22280	COG0204	Acyl-transferase
BsBEST3106_22290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3106_22300	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3106_22310	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3106_22330	COG2136	Putative SAM-dependent methyltransferase
BsBEST3106_22330	COG2521	methyltransferase
BsBEST3106_22350	COG0129	dihydroxy-acid dehydratase activity
BsBEST3106_22360	COG1413	lyase activity
BsBEST3106_22370	COG1418	mRNA catabolic process
BsBEST3106_22380	COG0386	Belongs to the glutathione peroxidase family
BsBEST3106_22390	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BsBEST3106_22400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3106_22410	COG1278	Cold shock
BsBEST3106_22450	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3106_22460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BsBEST3106_22470	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3106_22490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3106_22520	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3106_22530	COG1755	Isoprenylcysteine carboxyl methyltransferase
BsBEST3106_22540	COG3424	synthase
BsBEST3106_22550	COG2233	PERMEase
BsBEST3106_22560	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3106_22570	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BsBEST3106_22590	COG0800	Aldolase
BsBEST3106_22600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3106_22610	COG1609	Transcriptional regulator
BsBEST3106_22620	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BsBEST3106_22630	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_22640	COG1199	ATP-dependent helicase activity
BsBEST3106_22660	COG0116	Belongs to the methyltransferase superfamily
BsBEST3106_22680	COG4474	Belongs to the UPF0398 family
BsBEST3106_22690	COG3359	exonuclease
BsBEST3106_22700	COG1111	helicase
BsBEST3106_22700	COG1205	dead DEAH box helicase
BsBEST3106_22710	COG2190	(PTS) system
BsBEST3106_22720	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3106_22780	COG3331	DNA recombination
BsBEST3106_22790	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3106_22790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3106_22810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BsBEST3106_22820	COG3935	DnaD domain protein
BsBEST3106_22830	COG0017	Asparaginyl-tRNA synthetase
BsBEST3106_22840	COG0436	Aminotransferase
BsBEST3106_22850	COG5353	protein conserved in bacteria
BsBEST3106_22870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BsBEST3106_22870	COG1199	ATP-dependent helicase activity
BsBEST3106_22880	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BsBEST3106_22890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BsBEST3106_22900	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BsBEST3106_22910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BsBEST3106_22910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BsBEST3106_22920	COG0617	tRNA 3'-terminal CCA addition
BsBEST3106_22930	COG0438	transferase activity, transferring glycosyl groups
BsBEST3106_22940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3106_22950	COG1803	Methylglyoxal synthase
BsBEST3106_22960	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BsBEST3106_22970	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3106_22980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3106_23000	COG4347	Protein of unknown function (DUF1405)
BsBEST3106_23010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3106_23010	COG2010	Cytochrome c
BsBEST3106_23020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3106_23030	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3106_23050	COG5582	Belongs to the UPF0302 family
BsBEST3106_23060	COG0457	Tetratricopeptide repeat
BsBEST3106_23070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BsBEST3106_23080	COG0287	Prephenate dehydrogenase
BsBEST3106_23090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BsBEST3106_23100	COG0159	tryptophan synthase activity
BsBEST3106_23110	COG0133	tryptophan synthase activity
BsBEST3106_23120	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3106_23140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BsBEST3106_23150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3106_23160	COG4401	Chorismate mutase type I
BsBEST3106_23170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BsBEST3106_23180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BsBEST3106_23190	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BsBEST3106_23200	COG0105	UTP biosynthetic process
BsBEST3106_23210	COG0142	geranyltranstransferase activity
BsBEST3106_23220	COG2226	methyltransferase
BsBEST3106_23230	COG0142	geranyltranstransferase activity
BsBEST3106_23250	COG0302	gtp cyclohydrolase
BsBEST3106_23260	COG0776	regulation of translation
BsBEST3106_23270	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3106_23300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BsBEST3106_23310	COG1160	GTP binding
BsBEST3106_23360	COG1304	FMN binding
BsBEST3106_23370	COG0539	negative regulation of cytoplasmic translation
BsBEST3106_23380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BsBEST3106_23400	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BsBEST3106_23410	COG2959	enzyme of heme biosynthesis
BsBEST3106_23420	COG3773	Cell wall hydrolase
BsBEST3106_23420	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_23430	COG2339	peptidase activity
BsBEST3106_23440	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3106_23450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3106_23460	COG4862	establishment of competence for transformation
BsBEST3106_23470	COG1408	metallophosphoesterase
BsBEST3106_23480	COG1388	LysM domain
BsBEST3106_23490	COG1266	CAAX protease self-immunity
BsBEST3106_23500	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3106_23510	COG4955	Helix-turn-helix domain
BsBEST3106_23520	COG1141	Ferredoxin
BsBEST3106_23530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BsBEST3106_23550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3106_23560	COG0710	3-dehydroquinate dehydratase activity
BsBEST3106_23580	COG1595	DNA-templated transcription, initiation
BsBEST3106_23590	COG5002	protein histidine kinase activity
BsBEST3106_23600	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_23610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3106_23620	COG1333	cytochrome c biogenesis protein
BsBEST3106_23630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_23640	COG1187	pseudouridine synthase activity
BsBEST3106_23650	COG0700	Nucleoside recognition
BsBEST3106_23660	COG2715	membrane protein required for spore maturation
BsBEST3106_23670	COG1686	Belongs to the peptidase S11 family
BsBEST3106_23690	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BsBEST3106_23700	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BsBEST3106_23710	COG1547	Domain of unknown function (DUF309)
BsBEST3106_23720	COG0456	acetyltransferase
BsBEST3106_23730	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BsBEST3106_23740	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3106_23740	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3106_23750	COG0307	riboflavin synthase, alpha
BsBEST3106_23760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3106_23760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3106_23780	COG0681	Belongs to the peptidase S26 family
BsBEST3106_23800	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BsBEST3106_23830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BsBEST3106_23840	COG4086	secreted protein
BsBEST3106_23850	COG0019	diaminopimelate decarboxylase activity
BsBEST3106_23860	COG0697	spore germination
BsBEST3106_23890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3106_23930	COG1191	sigma factor activity
BsBEST3106_23940	COG2172	sigma factor antagonist activity
BsBEST3106_23950	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3106_23960	COG1686	Belongs to the peptidase S11 family
BsBEST3106_23970	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BsBEST3106_23980	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BsBEST3106_23990	COG4974	Belongs to the 'phage' integrase family
BsBEST3106_24010	COG0735	belongs to the Fur family
BsBEST3106_24020	COG1300	Membrane
BsBEST3106_24040	COG0281	malic enzyme
BsBEST3106_24050	COG1757	Na H antiporter
BsBEST3106_24060	COG1027	Aspartate ammonia-lyase
BsBEST3106_24070	COG0252	asparaginase activity
BsBEST3106_24080	COG1396	sequence-specific DNA binding
BsBEST3106_24090	COG1379	DNA repair
BsBEST3106_24100	COG0494	nUDIX hydrolase
BsBEST3106_24120	COG0667	Aldo Keto reductase
BsBEST3106_24140	COG1073	alpha beta
BsBEST3106_24160	COG4918	Iron-sulphur cluster biosynthesis
BsBEST3106_24170	COG0456	acetyltransferase
BsBEST3106_24170	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BsBEST3106_24180	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3106_24190	COG0456	acetyltransferase
BsBEST3106_24210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3106_24230	COG2211	Major facilitator Superfamily
BsBEST3106_24250	COG0346	lactoylglutathione lyase activity
BsBEST3106_24260	COG1072	(Pantothenic acid kinase))
BsBEST3106_24270	COG3048	D-serine ammonia-lyase activity
BsBEST3106_24280	COG0300	oxidoreductase activity
BsBEST3106_24290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3106_24300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3106_24310	COG4187	Peptidase family M20/M25/M40
BsBEST3106_24320	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3106_24330	COG0596	Alpha beta hydrolase
BsBEST3106_24340	COG1234	tRNA 3'-trailer cleavage
BsBEST3106_24350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BsBEST3106_24360	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3106_24370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3106_24390	COG0706	membrane insertase activity
BsBEST3106_24400	COG3361	conserved protein (COG2071)
BsBEST3106_24410	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3106_24420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3106_24430	COG0346	lactoylglutathione lyase activity
BsBEST3106_24440	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3106_24450	COG4129	membrane
BsBEST3106_24460	COG1126	abc transporter atp-binding protein
BsBEST3106_24470	COG0765	amino acid transport
BsBEST3106_24480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3106_24500	COG1597	lipid kinase activity
BsBEST3106_24510	COG2814	Major facilitator Superfamily
BsBEST3106_24520	COG0789	Transcriptional regulator
BsBEST3106_24520	COG4978	Transcriptional regulator
BsBEST3106_24530	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3106_24540	COG0022	dehydrogenase e1 component
BsBEST3106_24550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3106_24560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3106_24570	COG3426	butyrate kinase activity
BsBEST3106_24580	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3106_24590	COG0280	phosphate acetyltransferase
BsBEST3106_24600	COG3290	protein histidine kinase activity
BsBEST3106_24600	COG3829	transcription factor binding
BsBEST3106_24620	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BsBEST3106_24630	COG2079	MmgE PrpD family protein
BsBEST3106_24640	COG0372	Belongs to the citrate synthase family
BsBEST3106_24650	COG1960	acyl-CoA dehydrogenase activity
BsBEST3106_24660	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3106_24670	COG0183	Belongs to the thiolase family
BsBEST3106_24680	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3106_24690	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_24710	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3106_24720	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_24730	COG0750	zinc metalloprotease
BsBEST3106_24740	COG0497	DNA recombination
BsBEST3106_24750	COG1438	arginine binding
BsBEST3106_24760	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BsBEST3106_24770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BsBEST3106_24780	COG0142	geranyltranstransferase activity
BsBEST3106_24790	COG1722	exodeoxyribonuclease VII activity
BsBEST3106_24800	COG1570	exodeoxyribonuclease VII activity
BsBEST3106_24810	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BsBEST3106_24820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3106_24830	COG1302	Protein conserved in bacteria
BsBEST3106_24840	COG0439	Biotin carboxylase
BsBEST3106_24850	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3106_24930	COG3854	ATPases associated with a variety of cellular activities
BsBEST3106_24950	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BsBEST3106_24960	COG0006	proline dipeptidase activity
BsBEST3106_24970	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BsBEST3106_24990	COG3872	metal-dependent enzyme
BsBEST3106_25010	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3106_25020	COG1321	iron dependent repressor
BsBEST3106_25030	COG0095	Lipoate-protein ligase
BsBEST3106_25040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3106_25050	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3106_25060	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3106_25070	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BsBEST3106_25080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3106_25110	COG1396	sequence-specific DNA binding
BsBEST3106_25130	COG0681	Belongs to the peptidase S26 family
BsBEST3106_25180	COG4940	Competence protein ComGF
BsBEST3106_25200	COG4970	Tfp pilus assembly protein FimT
BsBEST3106_25210	COG4537	Required for transformation and DNA binding
BsBEST3106_25220	COG1459	type II secretion system
BsBEST3106_25230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BsBEST3106_25240	COG0598	Magnesium transport protein CorA
BsBEST3106_25250	COG1253	flavin adenine dinucleotide binding
BsBEST3106_25260	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3106_25270	COG1393	Belongs to the ArsC family
BsBEST3106_25290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3106_25310	COG0011	TIGRFAM Protein of
BsBEST3106_25330	COG2866	Carboxypeptidase
BsBEST3106_25340	COG1368	sulfuric ester hydrolase activity
BsBEST3106_25350	COG1940	carbohydrate kinase activity
BsBEST3106_25360	COG4483	Protein conserved in bacteria
BsBEST3106_25370	COG0457	Tetratricopeptide repeat
BsBEST3106_25370	COG0705	Rhomboid family
BsBEST3106_25390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BsBEST3106_25410	COG0438	transferase activity, transferring glycosyl groups
BsBEST3106_25440	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3106_25450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3106_25460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3106_25470	COG0581	inorganic phosphate transmembrane transporter activity
BsBEST3106_25480	COG0573	inorganic phosphate transmembrane transporter activity
BsBEST3106_25490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BsBEST3106_25500	COG0768	penicillin binding
BsBEST3106_25510	COG0477	Major facilitator Superfamily
BsBEST3106_25520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3106_25530	COG2839	Protein conserved in bacteria
BsBEST3106_25540	COG5521	maltodextrose utilization protein MalA
BsBEST3106_25560	COG1388	LysM domain
BsBEST3106_25570	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BsBEST3106_25580	COG4709	membrane
BsBEST3106_25590	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BsBEST3106_25600	COG0735	belongs to the Fur family
BsBEST3106_25610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3106_25630	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BsBEST3106_25640	COG0513	Belongs to the DEAD box helicase family
BsBEST3106_25660	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BsBEST3106_25670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BsBEST3106_25680	COG2384	SAM-dependent methyltransferase
BsBEST3106_25690	COG2010	Cytochrome c
BsBEST3106_25700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BsBEST3106_25710	COG0358	DNA primase activity
BsBEST3106_25720	COG1671	Belongs to the UPF0178 family
BsBEST3106_25730	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BsBEST3106_25740	COG0517	IMP dehydrogenase activity
BsBEST3106_25750	COG0751	glycine-tRNA ligase activity
BsBEST3106_25760	COG0752	glycyl-tRNA synthetase alpha subunit
BsBEST3106_25770	COG1381	Involved in DNA repair and RecF pathway recombination
BsBEST3106_25790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BsBEST3106_25800	COG0295	cytidine deaminase activity
BsBEST3106_25810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BsBEST3106_25820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BsBEST3106_25830	COG1480	7TM receptor with intracellular HD hydrolase
BsBEST3106_25840	COG1702	phosphate starvation-inducible protein PhoH
BsBEST3106_25850	COG0561	phosphatase activity
BsBEST3106_25880	COG4864	UPF0365 protein
BsBEST3106_25890	COG1030	water channel activity
BsBEST3106_25900	COG1610	YqeY-like protein
BsBEST3106_25920	COG1283	sodium-dependent phosphate transmembrane transporter activity
BsBEST3106_25930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3106_25940	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BsBEST3106_25950	COG2264	protein methyltransferase activity
BsBEST3106_25960	COG0484	heat shock protein binding
BsBEST3106_25970	COG0443	Heat shock 70 kDa protein
BsBEST3106_25980	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BsBEST3106_25990	COG1420	regulation of RNA biosynthetic process
BsBEST3106_26000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3106_26010	COG0481	GTPase activity
BsBEST3106_26030	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_26040	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BsBEST3106_26060	COG0268	Binds directly to 16S ribosomal RNA
BsBEST3106_26070	COG1466	dna polymerase III delta subunit
BsBEST3106_26090	COG0658	competence protein
BsBEST3106_26090	COG2333	competence protein COMEC
BsBEST3106_26110	COG2131	deaminase
BsBEST3106_26120	COG1596	polysaccharide export
BsBEST3106_26120	COG1555	photosystem II stabilization
BsBEST3106_26130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3106_26140	COG2226	methyltransferase
BsBEST3106_26150	COG0799	negative regulation of ribosome biogenesis
BsBEST3106_26160	COG1713	HD superfamily hydrolase involved in NAD metabolism
BsBEST3106_26170	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BsBEST3106_26180	COG1534	Rna-binding protein
BsBEST3106_26190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BsBEST3106_26200	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3106_26210	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BsBEST3106_26220	COG2755	lipolytic protein G-D-S-L family
BsBEST3106_26230	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_26230	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_26240	COG0398	Pfam SNARE associated Golgi protein
BsBEST3106_26250	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BsBEST3106_26270	COG3209	COG3209 Rhs family protein
BsBEST3106_26290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3106_26310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3106_26320	COG0798	PFAM Bile acid sodium symporter
BsBEST3106_26330	COG0346	lactoylglutathione lyase activity
BsBEST3106_26340	COG0640	Transcriptional regulator
BsBEST3106_26350	COG3403	YqcI/YcgG family
BsBEST3106_26360	COG0457	Tetratricopeptide repeat
BsBEST3106_26390	COG5444	nuclease activity
BsBEST3106_26440	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_26440	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_26450	COG4824	toxin secretion phage lysis holin
BsBEST3106_26510	COG3778	Protein conserved in bacteria
BsBEST3106_26520	COG3299	homolog of phage Mu protein gp47
BsBEST3106_26530	COG3628	GPW Gp25 family protein
BsBEST3106_26550	COG4193	domain, Protein
BsBEST3106_26560	COG1652	LysM domain
BsBEST3106_26570	COG3953	SLT domain
BsBEST3106_26570	COG5280	Phage tail tape measure protein TP901
BsBEST3106_26700	COG4653	Phage capsid family
BsBEST3106_26710	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3106_26730	COG2369	cell adhesion
BsBEST3106_26740	COG5518	Phage portal protein
BsBEST3106_26750	COG1783	phage Terminase large subunit
BsBEST3106_26760	COG5484	DNA packaging
BsBEST3106_26780	COG3677	Transposase
BsBEST3106_26810	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BsBEST3106_26830	COG1484	DNA-dependent DNA replication
BsBEST3106_26840	COG3935	DnaD domain protein
BsBEST3106_26850	COG3723	Recombinational DNA repair protein, rece pathway
BsBEST3106_26860	COG5377	YqaJ viral recombinase family
BsBEST3106_26920	COG1476	TRANSCRIPTIONal
BsBEST3106_26930	COG3620	sequence-specific DNA binding
BsBEST3106_26950	COG0563	adenylate kinase activity
BsBEST3106_26960	COG2856	Zn peptidase
BsBEST3106_26980	COG3223	Belongs to the PsiE family
BsBEST3106_26990	COG5002	protein histidine kinase activity
BsBEST3106_26990	COG0642	Histidine kinase
BsBEST3106_27000	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_27010	COG2311	Membrane
BsBEST3106_27020	COG0454	-acetyltransferase
BsBEST3106_27030	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3106_27050	COG0730	response to heat
BsBEST3106_27060	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3106_27070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3106_27070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3106_27080	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3106_27080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3106_27090	COG2210	Belongs to the sulfur carrier protein TusA family
BsBEST3106_27100	COG1937	Protein conserved in bacteria
BsBEST3106_27130	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3106_27150	COG0789	Transcriptional regulator
BsBEST3106_27150	COG4978	Transcriptional regulator
BsBEST3106_27160	COG2814	Major facilitator Superfamily
BsBEST3106_27170	COG0456	acetyltransferase
BsBEST3106_27180	COG1253	flavin adenine dinucleotide binding
BsBEST3106_27200	COG0697	spore germination
BsBEST3106_27210	COG0583	DNA-binding transcription factor activity
BsBEST3106_27220	COG2072	flavoprotein involved in K transport
BsBEST3106_27230	COG1230	cation diffusion facilitator family transporter
BsBEST3106_27240	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3106_27250	COG0583	DNA-binding transcription factor activity
BsBEST3106_27270	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3106_27280	COG1687	branched-chain amino acid
BsBEST3106_27290	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BsBEST3106_27300	COG1522	sequence-specific DNA binding
BsBEST3106_27310	COG2732	(Barnase) inhibitor
BsBEST3106_27320	COG2124	cytochrome p450
BsBEST3106_27350	COG1335	isochorismatase
BsBEST3106_27370	COG2318	DinB family
BsBEST3106_27390	COG2070	2-Nitropropane dioxygenase
BsBEST3106_27420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3106_27450	COG3443	Belongs to the bacterial solute-binding protein 9 family
BsBEST3106_27460	COG1595	DNA-templated transcription, initiation
BsBEST3106_27470	COG0667	Aldo Keto reductase
BsBEST3106_27480	COG2851	Citrate transporter
BsBEST3106_27490	COG0583	DNA-binding transcription factor activity
BsBEST3106_27500	COG2828	Protein conserved in bacteria
BsBEST3106_27520	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_27530	COG5566	PFAM Mor transcription activator
BsBEST3106_27540	COG0596	Alpha beta hydrolase
BsBEST3106_27550	COG4991	sh3 domain protein
BsBEST3106_27560	COG4991	sh3 domain protein
BsBEST3106_27570	COG0346	lactoylglutathione lyase activity
BsBEST3106_27590	COG5577	PFAM Coat F domain
BsBEST3106_27600	COG1063	alcohol dehydrogenase
BsBEST3106_27620	COG5577	PFAM Coat F domain
BsBEST3106_27630	COG0789	Transcriptional regulator
BsBEST3106_27650	COG1064	alcohol dehydrogenase
BsBEST3106_27660	COG0693	protein deglycase activity
BsBEST3106_27670	COG1621	beta-fructofuranosidase activity
BsBEST3106_27690	COG3716	PTS system mannose fructose sorbose family IID component
BsBEST3106_27700	COG3715	PTS system
BsBEST3106_27710	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3106_27720	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3106_27730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3106_27730	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BsBEST3106_27740	COG1113	amino acid transport
BsBEST3106_27750	COG1280	lysine exporter protein (LysE YggA)
BsBEST3106_27760	COG1378	Sugar-specific transcriptional regulator TrmB
BsBEST3106_27770	COG1595	DNA-templated transcription, initiation
BsBEST3106_27790	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BsBEST3106_27790	COG2755	lipolytic protein G-D-S-L family
BsBEST3106_27810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3106_27810	COG2124	cytochrome p450
BsBEST3106_27820	COG1309	transcriptional regulator
BsBEST3106_27830	COG2226	methyltransferase
BsBEST3106_27850	COG2116	formate transmembrane transporter activity
BsBEST3106_27860	COG5609	conserved protein (DUF2294)
BsBEST3106_27870	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3106_27880	COG2427	Protein of unknown function (DUF1641)
BsBEST3106_27900	COG0626	cystathionine gamma-synthase activity
BsBEST3106_27910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3106_27920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BsBEST3106_27930	COG2226	methyltransferase
BsBEST3106_27960	COG0768	penicillin binding
BsBEST3106_27970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BsBEST3106_27980	COG0572	uridine kinase
BsBEST3106_27990	COG0826	peptidase U32
BsBEST3106_28000	COG0826	peptidase U32
BsBEST3106_28010	COG4122	O-methyltransferase activity
BsBEST3106_28020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3106_28030	COG3906	Belongs to the UPF0473 family
BsBEST3106_28040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BsBEST3106_28050	COG4472	Bacterial protein of unknown function (DUF965)
BsBEST3106_28060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BsBEST3106_28070	COG0628	permease
BsBEST3106_28080	COG1126	abc transporter atp-binding protein
BsBEST3106_28090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3106_28100	COG0765	amino acid transport
BsBEST3106_28110	COG0765	amino acid transport
BsBEST3106_28140	COG3881	PFAM PRC-barrel domain
BsBEST3106_28150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BsBEST3106_28160	COG0457	Tetratricopeptide repeat
BsBEST3106_28170	COG0482	sulfurtransferase activity
BsBEST3106_28180	COG1104	cysteine desulfurase activity
BsBEST3106_28190	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3106_28200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BsBEST3106_28210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BsBEST3106_28220	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BsBEST3106_28230	COG0124	histidyl-tRNA synthetase
BsBEST3106_28250	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_28250	COG3103	Sh3 type 3 domain protein
BsBEST3106_28250	COG4991	sh3 domain protein
BsBEST3106_28260	COG1490	D-aminoacyl-tRNA deacylase activity
BsBEST3106_28270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BsBEST3106_28280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3106_28290	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BsBEST3106_28290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3106_28300	COG5416	Lipopolysaccharide assembly protein A domain
BsBEST3106_28310	COG0490	domain, Protein
BsBEST3106_28320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3106_28320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3106_28340	COG2244	polysaccharide biosynthetic process
BsBEST3106_28350	COG2323	membrane
BsBEST3106_28370	COG1862	Preprotein translocase
BsBEST3106_28380	COG0343	queuine tRNA-ribosyltransferase activity
BsBEST3106_28390	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BsBEST3106_28410	COG2255	four-way junction helicase activity
BsBEST3106_28420	COG0632	four-way junction helicase activity
BsBEST3106_28440	COG2814	Major facilitator Superfamily
BsBEST3106_28450	COG0673	inositol 2-dehydrogenase activity
BsBEST3106_28460	COG2112	serine threonine protein kinase
BsBEST3106_28500	COG1115	amino acid carrier protein
BsBEST3106_28510	COG0217	transcriptional regulatory protein
BsBEST3106_28530	COG1388	LysM domain
BsBEST3106_28540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BsBEST3106_28550	COG0157	Belongs to the NadC ModD family
BsBEST3106_28560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BsBEST3106_28570	COG1104	cysteine desulfurase activity
BsBEST3106_28580	COG1827	regulation of RNA biosynthetic process
BsBEST3106_28590	COG0077	Prephenate dehydratase
BsBEST3106_28600	COG4492	Belongs to the UPF0735 family
BsBEST3106_28610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BsBEST3106_28620	COG3290	protein histidine kinase activity
BsBEST3106_28630	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BsBEST3106_28640	COG2868	ribosomal protein
BsBEST3106_28650	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BsBEST3106_28660	COG1994	Peptidase M50
BsBEST3106_28670	COG0739	heme binding
BsBEST3106_28680	COG2894	cell division
BsBEST3106_28690	COG0850	regulation of cytokinetic process
BsBEST3106_28700	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BsBEST3106_28720	COG1077	Cell shape determining protein MreB Mrl
BsBEST3106_28730	COG2003	Belongs to the UPF0758 family
BsBEST3106_28740	COG0424	maF-like protein
BsBEST3106_28760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BsBEST3106_28770	COG0285	dihydrofolate synthase activity
BsBEST3106_28780	COG0525	valine-tRNA ligase activity
BsBEST3106_28800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3106_28810	COG1388	LysM domain
BsBEST3106_28820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3106_28830	COG0113	porphobilinogen synthase activity
BsBEST3106_28840	COG1587	Uroporphyrinogen-III synthase
BsBEST3106_28850	COG0181	hydroxymethylbilane synthase activity
BsBEST3106_28860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3106_28870	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BsBEST3106_28890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BsBEST3106_28900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BsBEST3106_28910	COG0470	DNA polymerase III
BsBEST3106_28910	COG1067	ATP-dependent peptidase activity
BsBEST3106_28920	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BsBEST3106_28930	COG0544	peptidyl-prolyl cis-trans isomerase activity
BsBEST3106_28940	COG0457	Tetratricopeptide repeat
BsBEST3106_28940	COG1477	protein flavinylation
BsBEST3106_28950	COG0066	3-isopropylmalate dehydratase activity
BsBEST3106_28960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BsBEST3106_28970	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3106_28980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3106_28990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BsBEST3106_29000	COG0440	acetolactate synthase activity
BsBEST3106_29010	COG0028	Belongs to the TPP enzyme family
BsBEST3106_29030	COG0454	-acetyltransferase
BsBEST3106_29040	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BsBEST3106_29050	COG0622	Phosphoesterase
BsBEST3106_29060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BsBEST3106_29070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BsBEST3106_29080	COG5401	PFAM Sporulation and spore germination
BsBEST3106_29090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3106_29100	COG1846	Transcriptional regulator
BsBEST3106_29110	COG2197	response regulator
BsBEST3106_29120	COG0824	Thioesterase
BsBEST3106_29130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BsBEST3106_29140	COG1053	succinate dehydrogenase
BsBEST3106_29150	COG2009	succinate dehydrogenase
BsBEST3106_29160	COG1719	4-vinyl reductase, 4VR
BsBEST3106_29170	COG0527	aspartate kinase activity
BsBEST3106_29180	COG0322	excinuclease ABC activity
BsBEST3106_29190	COG3118	belongs to the thioredoxin family
BsBEST3106_29200	COG3534	alpha-L-arabinofuranosidase
BsBEST3106_29210	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BsBEST3106_29220	COG2086	electron transfer activity
BsBEST3106_29230	COG1024	Enoyl-CoA hydratase
BsBEST3106_29240	COG1309	transcriptional regulator
BsBEST3106_29250	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3106_29260	COG3766	membrane
BsBEST3106_29270	COG1193	negative regulation of DNA recombination
BsBEST3106_29280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3106_29280	COG1796	DNA polymerase
BsBEST3106_29290	COG1286	toxin biosynthetic process
BsBEST3106_29300	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BsBEST3106_29310	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3106_29320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3106_29320	COG0072	phenylalanine-tRNA ligase activity
BsBEST3106_29330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BsBEST3106_29340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3106_29360	COG3835	regulator
BsBEST3106_29370	COG0277	FAD linked oxidase domain protein
BsBEST3106_29380	COG0247	lactate metabolic process
BsBEST3106_29390	COG0346	lactoylglutathione lyase activity
BsBEST3106_29410	COG1966	Carbon starvation protein
BsBEST3106_29420	COG3534	alpha-L-arabinofuranosidase
BsBEST3106_29430	COG0395	ABC-type sugar transport system, permease component
BsBEST3106_29440	COG1175	transmembrane transport
BsBEST3106_29450	COG1653	transport
BsBEST3106_29460	COG0371	Dehydrogenase
BsBEST3106_29470	COG0647	UMP catabolic process
BsBEST3106_29480	COG0235	Class ii aldolase
BsBEST3106_29490	COG1069	ribulokinase activity
BsBEST3106_29500	COG2160	L-arabinose isomerase activity
BsBEST3106_29510	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3106_29520	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3106_29530	COG1363	Peptidase, m42
BsBEST3106_29550	COG3326	Membrane
BsBEST3106_29560	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BsBEST3106_29570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BsBEST3106_29580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BsBEST3106_29600	COG1346	cytolysis
BsBEST3106_29610	COG1380	Effector of murein hydrolase LrgA
BsBEST3106_29620	COG3279	Response regulator of the LytR AlgR family
BsBEST3106_29630	COG3275	phosphorelay sensor kinase activity
BsBEST3106_29640	COG1011	Hydrolase
BsBEST3106_29650	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3106_29670	COG0398	Pfam SNARE associated Golgi protein
BsBEST3106_29680	COG1484	DNA-dependent DNA replication
BsBEST3106_29690	COG3611	Membrane attachment protein
BsBEST3106_29700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BsBEST3106_29710	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BsBEST3106_29720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3106_29730	COG1733	regulation of RNA biosynthetic process
BsBEST3106_29740	COG2814	Major facilitator Superfamily
BsBEST3106_29750	COG0656	L-ascorbic acid biosynthetic process
BsBEST3106_29760	COG0237	dephospho-CoA kinase activity
BsBEST3106_29770	COG1971	Probably functions as a manganese efflux pump
BsBEST3106_29780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BsBEST3106_29790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3106_29790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3106_29800	COG5002	protein histidine kinase activity
BsBEST3106_29810	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_29820	COG0039	L-malate dehydrogenase activity
BsBEST3106_29830	COG0538	isocitrate dehydrogenase activity
BsBEST3106_29840	COG0372	Belongs to the citrate synthase family
BsBEST3106_29850	COG2707	UPF0756 membrane protein
BsBEST3106_29860	COG0628	permease
BsBEST3106_29870	COG3030	protein affecting phage T7 exclusion by the F plasmid
BsBEST3106_29880	COG0469	pyruvate kinase activity
BsBEST3106_29890	COG0205	6-phosphofructokinase activity
BsBEST3106_29900	COG0825	malonyl-CoA metabolic process
BsBEST3106_29910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BsBEST3106_29920	COG0281	malic enzyme
BsBEST3106_29930	COG0587	DNA-directed DNA polymerase activity
BsBEST3106_29970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BsBEST3106_29990	COG4109	DRTGG domain
BsBEST3106_30000	COG0730	response to heat
BsBEST3106_30010	COG1473	amidohydrolase
BsBEST3106_30020	COG0196	riboflavin kinase activity
BsBEST3106_30030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3106_30040	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BsBEST3106_30050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3106_30060	COG1126	abc transporter atp-binding protein
BsBEST3106_30070	COG0765	amino acid transport
BsBEST3106_30080	COG0765	amino acid transport
BsBEST3106_30090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3106_30100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3106_30110	COG0454	-acetyltransferase
BsBEST3106_30120	COG0583	DNA-binding transcription factor activity
BsBEST3106_30130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3106_30140	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_30160	COG0165	Argininosuccinate lyase
BsBEST3106_30170	COG0137	argininosuccinate synthase activity
BsBEST3106_30180	COG0521	Mo-molybdopterin cofactor biosynthetic process
BsBEST3106_30190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BsBEST3106_30200	COG0827	DNA restriction-modification system
BsBEST3106_30210	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BsBEST3106_30220	COG3874	Sporulation protein YtfJ
BsBEST3106_30240	COG1714	RDD family
BsBEST3106_30250	COG0616	signal peptide processing
BsBEST3106_30260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3106_30270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BsBEST3106_30280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3106_30300	COG0301	tRNA thio-modification
BsBEST3106_30310	COG1104	cysteine desulfurase activity
BsBEST3106_30320	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3106_30330	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BsBEST3106_30340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3106_30350	COG1309	transcriptional regulator
BsBEST3106_30360	COG1956	GAF domain-containing protein
BsBEST3106_30370	COG2199	diguanylate cyclase activity
BsBEST3106_30370	COG2203	Gaf domain
BsBEST3106_30380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BsBEST3106_30400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3106_30410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3106_30420	COG0454	-acetyltransferase
BsBEST3106_30430	COG0517	IMP dehydrogenase activity
BsBEST3106_30440	COG0123	including yeast histone deacetylase and acetoin utilization protein
BsBEST3106_30450	COG1360	Flagellar Motor Protein
BsBEST3106_30460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3106_30470	COG1609	Transcriptional regulator
BsBEST3106_30480	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BsBEST3106_30480	COG1605	Chorismate mutase
BsBEST3106_30490	COG3118	belongs to the thioredoxin family
BsBEST3106_30500	COG4980	gas vesicle protein
BsBEST3106_30510	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3106_30520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BsBEST3106_30530	COG1674	ftsk spoiiie
BsBEST3106_30540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3106_30550	COG4848	Belongs to the UPF0354 family
BsBEST3106_30560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_30580	COG1363	Peptidase, m42
BsBEST3106_30590	COG5584	Small secreted protein
BsBEST3106_30600	COG0281	malic enzyme
BsBEST3106_30610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3106_30620	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BsBEST3106_30640	COG0510	thiamine kinase activity
BsBEST3106_30650	COG1523	belongs to the glycosyl hydrolase 13 family
BsBEST3106_30660	COG1597	lipid kinase activity
BsBEST3106_30680	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3106_30690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3106_30700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3106_30710	COG2252	PERMEase
BsBEST3106_30720	COG4473	ABC transporter
BsBEST3106_30730	COG1131	(ABC) transporter
BsBEST3106_30750	COG1349	DNA-binding transcription factor activity
BsBEST3106_30760	COG1187	pseudouridine synthase activity
BsBEST3106_30770	COG2244	polysaccharide biosynthetic process
BsBEST3106_30780	COG2081	HI0933 family
BsBEST3106_30790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BsBEST3106_30810	COG5578	integral membrane protein
BsBEST3106_30820	COG0673	inositol 2-dehydrogenase activity
BsBEST3106_30830	COG1653	transport
BsBEST3106_30840	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3106_30850	COG4209	transmembrane transport
BsBEST3106_30860	COG2207	Transcriptional regulator
BsBEST3106_30870	COG2207	Transcriptional regulator
BsBEST3106_30880	COG1653	transport
BsBEST3106_30890	COG0395	ABC-type sugar transport system, permease component
BsBEST3106_30900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3106_30910	COG2124	cytochrome p450
BsBEST3106_30920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BsBEST3106_30930	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BsBEST3106_30940	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3106_30950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3106_30960	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BsBEST3106_30970	COG1073	alpha beta
BsBEST3106_30980	COG1609	Transcriptional regulator
BsBEST3106_30990	COG1653	transport
BsBEST3106_31000	COG1175	transmembrane transport
BsBEST3106_31010	COG0395	ABC-type sugar transport system, permease component
BsBEST3106_31020	COG1486	melibiose metabolic process
BsBEST3106_31030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3106_31040	COG0495	leucyl-tRNA aminoacylation
BsBEST3106_31060	COG2202	Pas domain
BsBEST3106_31060	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3106_31070	COG2814	Major facilitator Superfamily
BsBEST3106_31080	COG2433	Pfam Transposase IS66
BsBEST3106_31090	COG0577	efflux transmembrane transporter activity
BsBEST3106_31100	COG1136	(ABC) transporter
BsBEST3106_31110	COG2205	protein histidine kinase activity
BsBEST3106_31120	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_31130	COG0577	efflux transmembrane transporter activity
BsBEST3106_31140	COG1136	(ABC) transporter
BsBEST3106_31170	COG1131	(ABC) transporter
BsBEST3106_31180	COG1725	Transcriptional regulator
BsBEST3106_31200	COG1242	4 iron, 4 sulfur cluster binding
BsBEST3106_31210	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BsBEST3106_31230	COG2267	carboxylic ester hydrolase activity
BsBEST3106_31240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BsBEST3106_31250	COG1113	amino acid transport
BsBEST3106_31260	COG0367	asparagine synthase
BsBEST3106_31270	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BsBEST3106_31280	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BsBEST3106_31300	COG1506	peptidase
BsBEST3106_31310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3106_31320	COG1116	anion transmembrane transporter activity
BsBEST3106_31330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3106_31340	COG0494	nUDIX hydrolase
BsBEST3106_31350	COG4824	toxin secretion phage lysis holin
BsBEST3106_31360	COG0783	Belongs to the Dps family
BsBEST3106_31390	COG1854	S-ribosylhomocysteine lyase activity
BsBEST3106_31400	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BsBEST3106_31410	COG0288	reversible hydration of carbon dioxide
BsBEST3106_31420	COG0254	rRNA binding
BsBEST3106_31430	COG1271	oxidase subunit
BsBEST3106_31440	COG1294	oxidase, subunit
BsBEST3106_31460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3106_31470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3106_31470	COG1321	iron dependent repressor
BsBEST3106_31480	COG1121	(ABC) transporter
BsBEST3106_31490	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3106_31500	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3106_31510	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3106_31520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BsBEST3106_31530	COG0596	Alpha beta hydrolase
BsBEST3106_31540	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BsBEST3106_31550	COG1169	isochorismate synthase
BsBEST3106_31560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3106_31570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3106_31580	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3106_31590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3106_31600	COG0438	transferase activity, transferring glycosyl groups
BsBEST3106_31620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3106_31630	COG0438	transferase activity, transferring glycosyl groups
BsBEST3106_31640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3106_31650	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BsBEST3106_31660	COG0058	SHG alpha-glucan phosphorylase activity
BsBEST3106_31670	COG0297	glycogen (starch) synthase activity
BsBEST3106_31680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3106_31690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3106_31700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BsBEST3106_31710	COG3859	Proton-coupled thiamine transporter YuaJ
BsBEST3106_31720	COG1247	-acetyltransferase
BsBEST3106_31730	COG2268	Band 7 protein
BsBEST3106_31740	COG1585	Membrane protein implicated in regulation of membrane protease activity
BsBEST3106_31750	COG2318	DinB family
BsBEST3106_31770	COG1454	alcohol dehydrogenase
BsBEST3106_31780	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_31790	COG1510	regulation of RNA biosynthetic process
BsBEST3106_31810	COG0569	domain protein
BsBEST3106_31820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3106_31830	COG4682	membrane
BsBEST3106_31840	COG1705	Flagellar rod assembly protein muramidase FlgJ
BsBEST3106_31850	COG0477	Major facilitator Superfamily
BsBEST3106_31860	COG5553	Cysteine dioxygenase type I
BsBEST3106_31870	COG1968	undecaprenyl-diphosphatase activity
BsBEST3106_31880	COG0628	permease
BsBEST3106_31890	COG0673	inositol 2-dehydrogenase activity
BsBEST3106_31900	COG4806	L-rhamnose isomerase
BsBEST3106_31910	COG3254	rhamnose metabolic process
BsBEST3106_31920	COG1070	Carbohydrate kinase
BsBEST3106_31930	COG1349	DNA-binding transcription factor activity
BsBEST3106_31940	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_31940	COG3347	Dehydrogenase
BsBEST3106_31950	COG0840	transmembrane signaling receptor activity
BsBEST3106_31960	COG0840	transmembrane signaling receptor activity
BsBEST3106_31980	COG0840	transmembrane signaling receptor activity
BsBEST3106_31990	COG0840	transmembrane signaling receptor activity
BsBEST3106_32020	COG0432	Pfam Uncharacterised protein family UPF0047
BsBEST3106_32040	COG0366	Alpha amylase catalytic
BsBEST3106_32050	COG1253	flavin adenine dinucleotide binding
BsBEST3106_32060	COG2738	Putative neutral zinc metallopeptidase
BsBEST3106_32090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BsBEST3106_32120	COG0166	Belongs to the GPI family
BsBEST3106_32130	COG1979	alcohol dehydrogenase
BsBEST3106_32140	COG1979	alcohol dehydrogenase
BsBEST3106_32150	COG2155	Conserved Protein
BsBEST3106_32160	COG1098	S1 RNA binding domain
BsBEST3106_32170	COG0436	Aminotransferase
BsBEST3106_32180	COG1522	sequence-specific DNA binding
BsBEST3106_32190	COG2267	carboxylic ester hydrolase activity
BsBEST3106_32210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BsBEST3106_32220	COG2205	protein histidine kinase activity
BsBEST3106_32240	COG5018	Exonuclease
BsBEST3106_32260	COG2814	Major facilitator Superfamily
BsBEST3106_32270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3106_32280	COG3011	Protein conserved in bacteria
BsBEST3106_32300	COG3290	protein histidine kinase activity
BsBEST3106_32310	COG4565	transcriptional regulatory protein
BsBEST3106_32320	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3106_32330	COG3845	ABC transporter
BsBEST3106_32340	COG4603	Belongs to the binding-protein-dependent transport system permease family
BsBEST3106_32350	COG1079	Belongs to the binding-protein-dependent transport system permease family
BsBEST3106_32360	COG3493	citrate carrier protein
BsBEST3106_32380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3106_32380	COG2111	Na H antiporter
BsBEST3106_32390	COG2111	Na H antiporter
BsBEST3106_32400	COG1006	Multisubunit Na H antiporter MnhC subunit
BsBEST3106_32410	COG0651	ATP synthesis coupled electron transport
BsBEST3106_32420	COG1863	multisubunit Na H antiporter MnhE subunit
BsBEST3106_32430	COG2212	antiporter activity
BsBEST3106_32440	COG1320	monovalent cation:proton antiporter activity
BsBEST3106_32450	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3106_32460	COG2197	response regulator
BsBEST3106_32470	COG4585	Histidine kinase
BsBEST3106_32500	COG0142	geranyltranstransferase activity
BsBEST3106_32530	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BsBEST3106_32540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BsBEST3106_32550	COG1335	isochorismatase
BsBEST3106_32560	COG5506	Protein of unknown function (DUF1694)
BsBEST3106_32590	COG0628	permease
BsBEST3106_32620	COG1418	mRNA catabolic process
BsBEST3106_32630	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_32650	COG1511	domain protein
BsBEST3106_32660	COG0433	COG0433 Predicted ATPase
BsBEST3106_32660	COG1674	ftsk spoiiie
BsBEST3106_32670	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3106_32680	COG5417	Belongs to the EsaB family
BsBEST3106_32690	COG4842	Belongs to the WXG100 family
BsBEST3106_32700	COG2508	Transcriptional regulator
BsBEST3106_32700	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3106_32710	COG0686	Belongs to the AlaDH PNT family
BsBEST3106_32720	COG5634	Uncharacterized conserved protein (DUF2278)
BsBEST3106_32730	COG3251	PFAM MbtH domain protein
BsBEST3106_32740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_32750	COG1535	isochorismatase
BsBEST3106_32750	COG3433	isochorismatase activity
BsBEST3106_32760	COG1021	2,3-dihydroxybenzoate-AMP ligase
BsBEST3106_32770	COG1169	isochorismate synthase
BsBEST3106_32780	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_32790	COG2819	hydrolase of the alpha beta superfamily
BsBEST3106_32800	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3106_32810	COG1268	BioY protein
BsBEST3106_32820	COG2056	Na+-H+ antiporter family
BsBEST3106_32830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BsBEST3106_32840	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BsBEST3106_32850	COG3584	3D domain protein
BsBEST3106_32870	COG1252	NADH dehydrogenase
BsBEST3106_32880	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3106_32900	COG0516	GMP reductase activity
BsBEST3106_32910	COG2808	Putative FMN-binding domain
BsBEST3106_32920	COG0456	acetyltransferase
BsBEST3106_32930	COG0316	Belongs to the HesB IscA family
BsBEST3106_32940	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BsBEST3106_32950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3106_32960	COG4844	belongs to the
BsBEST3106_32970	COG1252	NADH dehydrogenase
BsBEST3106_32980	COG4837	Protein of unknown function (DUF1462)
BsBEST3106_32990	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BsBEST3106_33000	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3106_33000	COG1506	peptidase
BsBEST3106_33000	COG4946	Tricorn protease homolog
BsBEST3106_33010	COG0083	homoserine kinase activity
BsBEST3106_33020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BsBEST3106_33030	COG0460	homoserine dehydrogenase
BsBEST3106_33040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3106_33050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3106_33060	COG0647	UMP catabolic process
BsBEST3106_33070	COG2445	Protein of unknown function DUF86
BsBEST3106_33080	COG4470	Protein conserved in bacteria
BsBEST3106_33100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BsBEST3106_33110	COG0739	heme binding
BsBEST3106_33130	COG3377	Domain of unknown function (DUF1805)
BsBEST3106_33140	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3106_33150	COG0730	response to heat
BsBEST3106_33160	COG1801	Protein of unknown function DUF72
BsBEST3106_33180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3106_33190	COG2508	Transcriptional regulator
BsBEST3106_33200	COG2233	PERMEase
BsBEST3106_33210	COG2233	PERMEase
BsBEST3106_33220	COG3648	Uricase
BsBEST3106_33220	COG3195	allantoin biosynthetic process
BsBEST3106_33230	COG2351	hydroxyisourate hydrolase activity
BsBEST3106_33250	COG2080	2 iron, 2 sulfur cluster binding
BsBEST3106_33260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BsBEST3106_33270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BsBEST3106_33280	COG2068	MobA-Related Protein
BsBEST3106_33290	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BsBEST3106_33300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BsBEST3106_33310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3106_33320	COG2356	endonuclease I
BsBEST3106_33330	COG3842	ATPase activity
BsBEST3106_33340	COG2188	Transcriptional regulator
BsBEST3106_33350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3106_33360	COG0395	ABC-type sugar transport system, permease component
BsBEST3106_33370	COG1175	transmembrane transport
BsBEST3106_33380	COG1653	transport
BsBEST3106_33390	COG2222	sugar isomerase
BsBEST3106_33400	COG0322	excinuclease ABC activity
BsBEST3106_33410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3106_33440	COG0346	lactoylglutathione lyase activity
BsBEST3106_33450	COG0640	Transcriptional regulator
BsBEST3106_33460	COG0719	Fe-S assembly protein
BsBEST3106_33470	COG0822	iron-sulfur transferase activity
BsBEST3106_33480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3106_33490	COG0719	Fe-S assembly protein
BsBEST3106_33500	COG0396	ATPase activity
BsBEST3106_33520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3106_33530	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3106_33540	COG2011	ABC-type metal ion transport system permease component
BsBEST3106_33550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BsBEST3106_33570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3106_33580	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3106_33600	COG0509	glycine decarboxylation via glycine cleavage system
BsBEST3106_33610	COG1393	Belongs to the ArsC family
BsBEST3106_33620	COG1960	acyl-CoA dehydrogenase activity
BsBEST3106_33630	COG0183	Belongs to the thiolase family
BsBEST3106_33640	COG1024	Enoyl-CoA hydratase
BsBEST3106_33640	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3106_33660	COG0506	proline dehydrogenase activity
BsBEST3106_33680	COG5577	PFAM Coat F domain
BsBEST3106_33690	COG1846	Transcriptional regulator
BsBEST3106_33700	COG0477	Major facilitator Superfamily
BsBEST3106_33710	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3106_33720	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_33730	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_33740	COG0583	DNA-binding transcription factor activity
BsBEST3106_33760	COG1120	ATPase activity
BsBEST3106_33800	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_33810	COG0783	Belongs to the Dps family
BsBEST3106_33820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3106_33830	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_33840	COG2205	protein histidine kinase activity
BsBEST3106_33840	COG2770	Histidine kinase
BsBEST3106_33860	COG1309	transcriptional regulator
BsBEST3106_33870	COG0114	fumarate hydratase activity
BsBEST3106_33890	COG0697	spore germination
BsBEST3106_33900	COG0814	amino acid
BsBEST3106_33930	COG2197	response regulator
BsBEST3106_33940	COG4585	Histidine kinase
BsBEST3106_33950	COG4758	membrane
BsBEST3106_33960	COG3595	metallopeptidase activity
BsBEST3106_33970	COG1842	Phage shock protein A
BsBEST3106_33980	COG4758	membrane
BsBEST3106_33990	COG2814	Major facilitator Superfamily
BsBEST3106_34000	COG2096	Adenosyltransferase
BsBEST3106_34010	COG1120	ATPase activity
BsBEST3106_34020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3106_34030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3106_34040	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_34050	COG3386	PFAM SMP-30 Gluconolaconase
BsBEST3106_34060	COG2205	protein histidine kinase activity
BsBEST3106_34070	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_34090	COG1191	sigma factor activity
BsBEST3106_34110	COG2140	Oxalate decarboxylase
BsBEST3106_34130	COG0577	efflux transmembrane transporter activity
BsBEST3106_34140	COG1136	(ABC) transporter
BsBEST3106_34150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3106_34160	COG1120	ATPase activity
BsBEST3106_34170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3106_34180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3106_34190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3106_34200	COG0531	amino acid
BsBEST3106_34220	COG1988	membrane-bound metal-dependent
BsBEST3106_34230	COG1368	sulfuric ester hydrolase activity
BsBEST3106_34240	COG1910	domain protein
BsBEST3106_34250	COG0725	ABC transporter, periplasmic molybdate-binding protein
BsBEST3106_34260	COG4149	molybdate abc transporter
BsBEST3106_34270	COG0656	L-ascorbic acid biosynthetic process
BsBEST3106_34290	COG0025	NhaP-type Na H and K H
BsBEST3106_34300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3106_34310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3106_34320	COG3973	AAA domain
BsBEST3106_34330	COG2860	membrane
BsBEST3106_34340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3106_34350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BsBEST3106_34360	COG2217	Heavy metal translocating P-type atpase
BsBEST3106_34370	COG2217	Heavy metal translocating P-type atpase
BsBEST3106_34380	COG2608	mercury ion transmembrane transporter activity
BsBEST3106_34390	COG1937	Protein conserved in bacteria
BsBEST3106_34400	COG0673	inositol 2-dehydrogenase activity
BsBEST3106_34410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3106_34420	COG1289	transmembrane transporter activity
BsBEST3106_34440	COG2076	Multidrug Resistance protein
BsBEST3106_34450	COG1309	transcriptional regulator
BsBEST3106_34460	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_34470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BsBEST3106_34480	COG0557	exoribonuclease II activity
BsBEST3106_34490	COG1647	Serine aminopeptidase, S33
BsBEST3106_34500	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3106_34510	COG0596	Alpha beta hydrolase
BsBEST3106_34520	COG1476	TRANSCRIPTIONal
BsBEST3106_34530	COG1396	sequence-specific DNA binding
BsBEST3106_34540	COG1396	sequence-specific DNA binding
BsBEST3106_34550	COG1733	regulation of RNA biosynthetic process
BsBEST3106_34560	COG0840	transmembrane signaling receptor activity
BsBEST3106_34570	COG1174	glycine betaine transport
BsBEST3106_34580	COG1732	Glycine betaine
BsBEST3106_34590	COG1174	glycine betaine transport
BsBEST3106_34600	COG0517	IMP dehydrogenase activity
BsBEST3106_34600	COG1125	glycine betaine transport
BsBEST3106_34610	COG1510	regulation of RNA biosynthetic process
BsBEST3106_34650	COG5658	integral membrane protein
BsBEST3106_34660	COG0640	Transcriptional regulator
BsBEST3106_34670	COG1174	glycine betaine transport
BsBEST3106_34680	COG1732	Glycine betaine
BsBEST3106_34690	COG1174	glycine betaine transport
BsBEST3106_34700	COG0517	IMP dehydrogenase activity
BsBEST3106_34700	COG1125	glycine betaine transport
BsBEST3106_34710	COG1510	regulation of RNA biosynthetic process
BsBEST3106_34720	COG2095	MarC family integral membrane protein
BsBEST3106_34740	COG3064	Membrane
BsBEST3106_34750	COG4640	response to antibiotic
BsBEST3106_34760	COG0456	acetyltransferase
BsBEST3106_34770	COG0148	phosphopyruvate hydratase activity
BsBEST3106_34780	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BsBEST3106_34790	COG0149	triose-phosphate isomerase activity
BsBEST3106_34800	COG0126	phosphoglycerate kinase activity
BsBEST3106_34810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3106_34820	COG2390	Transcriptional regulator
BsBEST3106_34830	COG2814	Major facilitator Superfamily
BsBEST3106_34840	COG1609	Transcriptional regulator
BsBEST3106_34850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3106_34860	COG0583	DNA-binding transcription factor activity
BsBEST3106_34870	COG0697	spore germination
BsBEST3106_34880	COG1113	amino acid transport
BsBEST3106_34890	COG3858	chitin binding
BsBEST3106_34900	COG1556	Lactate utilization protein
BsBEST3106_34910	COG1139	Iron-sulfur cluster binding protein
BsBEST3106_34920	COG0247	lactate metabolic process
BsBEST3106_34930	COG2197	response regulator
BsBEST3106_34940	COG4585	Histidine kinase
BsBEST3106_34950	COG0842	Transport permease protein
BsBEST3106_34960	COG1131	(ABC) transporter
BsBEST3106_34970	COG0596	Alpha beta hydrolase
BsBEST3106_34980	COG2208	phosphoserine phosphatase activity
BsBEST3106_34990	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BsBEST3106_35000	COG1874	Beta-galactosidase
BsBEST3106_35010	COG3833	ABC-type maltose transport systems, permease component
BsBEST3106_35020	COG1175	transmembrane transport
BsBEST3106_35030	COG2182	Extracellular solute-binding protein
BsBEST3106_35040	COG1609	Transcriptional regulator
BsBEST3106_35050	COG2186	Transcriptional regulator
BsBEST3106_35060	COG1620	l-lactate permease
BsBEST3106_35070	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BsBEST3106_35090	COG5039	Polysaccharide pyruvyl transferase
BsBEST3106_35100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3106_35110	COG0110	maltose O-acetyltransferase activity
BsBEST3106_35120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BsBEST3106_35130	COG2244	polysaccharide biosynthetic process
BsBEST3106_35140	COG1216	Glycosyl transferase, family 2
BsBEST3106_35150	COG5039	Polysaccharide pyruvyl transferase
BsBEST3106_35160	COG1216	Glycosyl transferase, family 2
BsBEST3106_35180	COG0438	transferase activity, transferring glycosyl groups
BsBEST3106_35190	COG1215	transferase activity, transferring glycosyl groups
BsBEST3106_35200	COG0438	transferase activity, transferring glycosyl groups
BsBEST3106_35210	COG1086	Polysaccharide biosynthesis protein
BsBEST3106_35220	COG0489	protein tyrosine kinase activity
BsBEST3106_35230	COG3944	biosynthesis protein
BsBEST3106_35240	COG1396	sequence-specific DNA binding
BsBEST3106_35250	COG2272	Belongs to the type-B carboxylesterase lipase family
BsBEST3106_35270	COG3479	Phenolic acid decarboxylase
BsBEST3106_35300	COG1794	racemase activity, acting on amino acids and derivatives
BsBEST3106_35310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3106_35320	COG1621	beta-fructofuranosidase activity
BsBEST3106_35330	COG1621	beta-fructofuranosidase activity
BsBEST3106_35340	COG0531	amino acid
BsBEST3106_35350	COG1309	transcriptional regulator
BsBEST3106_35360	COG2076	Multidrug Resistance protein
BsBEST3106_35370	COG2076	Multidrug Resistance protein
BsBEST3106_35390	COG0277	FAD linked oxidase domain protein
BsBEST3106_35400	COG3621	Patatin-like phospholipase
BsBEST3106_35410	COG0740	serine-type endopeptidase activity
BsBEST3106_35420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3106_35430	COG0366	Alpha amylase catalytic
BsBEST3106_35440	COG1554	hydrolase, family 65, central catalytic
BsBEST3106_35450	COG5521	maltodextrose utilization protein MalA
BsBEST3106_35460	COG3833	ABC-type maltose transport systems, permease component
BsBEST3106_35470	COG1175	transmembrane transport
BsBEST3106_35480	COG2182	Extracellular solute-binding protein
BsBEST3106_35500	COG1609	Transcriptional regulator
BsBEST3106_35510	COG1611	Belongs to the LOG family
BsBEST3106_35520	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3106_35530	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3106_35540	COG0288	reversible hydration of carbon dioxide
BsBEST3106_35550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3106_35560	COG0577	efflux transmembrane transporter activity
BsBEST3106_35570	COG1136	(ABC) transporter
BsBEST3106_35580	COG5002	protein histidine kinase activity
BsBEST3106_35590	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_35610	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BsBEST3106_35620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3106_35630	COG1481	regulation of sporulation
BsBEST3106_35640	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BsBEST3106_35650	COG1660	Displays ATPase and GTPase activities
BsBEST3106_35660	COG1051	belongs to the nudix hydrolase family
BsBEST3106_35670	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3106_35680	COG0791	NLP P60 protein
BsBEST3106_35680	COG3883	PFAM NLP P60 protein
BsBEST3106_35690	COG0457	Tetratricopeptide repeat
BsBEST3106_35700	COG1132	(ABC) transporter
BsBEST3106_35740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BsBEST3106_35740	COG0140	phosphoribosyl-ATP diphosphatase activity
BsBEST3106_35750	COG0107	imidazoleglycerol-phosphate synthase activity
BsBEST3106_35760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BsBEST3106_35770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BsBEST3106_35780	COG0131	Imidazoleglycerol-phosphate dehydratase
BsBEST3106_35790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BsBEST3106_35800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BsBEST3106_35810	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BsBEST3106_35820	COG4990	cell redox homeostasis
BsBEST3106_35830	COG5297	Belongs to the glycosyl hydrolase family 6
BsBEST3106_35840	COG0110	maltose O-acetyltransferase activity
BsBEST3106_35850	COG0546	phosphoglycolate phosphatase activity
BsBEST3106_35860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BsBEST3106_35870	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BsBEST3106_35880	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BsBEST3106_35890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BsBEST3106_35900	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3106_35910	COG2188	Transcriptional regulator
BsBEST3106_35920	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3106_35930	COG1846	Transcriptional regulator
BsBEST3106_35940	COG2124	cytochrome p450
BsBEST3106_35960	COG1846	Transcriptional regulator
BsBEST3106_35970	COG2814	Major facilitator Superfamily
BsBEST3106_35980	COG1950	PFAM Membrane protein of
BsBEST3106_35990	COG1983	PspC domain protein
BsBEST3106_36000	COG3595	metallopeptidase activity
BsBEST3106_36030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3106_36040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BsBEST3106_36050	COG0556	nucleotide-excision repair
BsBEST3106_36060	COG4897	Protein conserved in bacteria
BsBEST3106_36070	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3106_36070	COG3848	Pyruvate phosphate dikinase
BsBEST3106_36080	COG1309	transcriptional regulator
BsBEST3106_36090	COG2814	Major facilitator Superfamily
BsBEST3106_36100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3106_36120	COG0793	Belongs to the peptidase S41A family
BsBEST3106_36120	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3106_36130	COG2177	Part of the ABC transporter FtsEX involved in
BsBEST3106_36140	COG2884	Cell division ATP-binding protein ftsE
BsBEST3106_36150	COG2010	Cytochrome c
BsBEST3106_36160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3106_36170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BsBEST3106_36180	COG0653	protein targeting
BsBEST3106_36190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BsBEST3106_36210	COG1516	flagellar protein fliS
BsBEST3106_36220	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BsBEST3106_36230	COG1334	flagellar protein FlaG
BsBEST3106_36240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3106_36250	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BsBEST3106_36260	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BsBEST3106_36280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3106_36290	COG1256	bacterial-type flagellum assembly
BsBEST3106_36290	COG4786	Flagellar basal body rod
BsBEST3106_36300	COG3418	PFAM FlgN family protein
BsBEST3106_36310	COG2747	anti-sigma28 factor FlgM
BsBEST3106_36330	COG1040	competence protein
BsBEST3106_36350	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BsBEST3106_36360	COG1307	EDD domain protein, DegV family
BsBEST3106_36370	COG2197	response regulator
BsBEST3106_36380	COG4585	Histidine kinase
BsBEST3106_36390	COG1739	Uncharacterized protein family UPF0029
BsBEST3106_36400	COG1316	TRANSCRIPTIONal
BsBEST3106_36410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3106_36420	COG0438	transferase activity, transferring glycosyl groups
BsBEST3106_36430	COG1215	transferase activity, transferring glycosyl groups
BsBEST3106_36440	COG3206	protein involved in exopolysaccharide biosynthesis
BsBEST3106_36450	COG3307	-O-antigen
BsBEST3106_36460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3106_36470	COG0297	glycogen (starch) synthase activity
BsBEST3106_36470	COG0438	transferase activity, transferring glycosyl groups
BsBEST3106_36480	COG2244	polysaccharide biosynthetic process
BsBEST3106_36510	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3106_36510	COG2247	cell wall binding repeat
BsBEST3106_36520	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3106_36520	COG2247	cell wall binding repeat
BsBEST3106_36540	COG1316	TRANSCRIPTIONal
BsBEST3106_36550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BsBEST3106_36560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3106_36570	COG1215	transferase activity, transferring glycosyl groups
BsBEST3106_36570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3106_36580	COG0463	Glycosyl transferase, family 2
BsBEST3106_36600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3106_36610	COG1134	teichoic acid transport
BsBEST3106_36620	COG1682	transport, permease protein
BsBEST3106_36630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3106_36640	COG0438	transferase activity, transferring glycosyl groups
BsBEST3106_36650	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BsBEST3106_36660	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BsBEST3106_36670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3106_36690	COG4193	domain, Protein
BsBEST3106_36700	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3106_36710	COG0697	spore germination
BsBEST3106_36720	COG0814	amino acid
BsBEST3106_36740	COG2814	Major facilitator Superfamily
BsBEST3106_36750	COG1316	TRANSCRIPTIONal
BsBEST3106_36760	COG0561	phosphatase activity
BsBEST3106_36770	COG0791	NLP P60 protein
BsBEST3106_36790	COG2843	Capsule synthesis protein
BsBEST3106_36810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3106_36820	COG1609	Transcriptional regulator
BsBEST3106_36830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3106_36840	COG1869	D-ribose catabolic process
BsBEST3106_36850	COG1129	ABC transporter
BsBEST3106_36860	COG1172	Belongs to the binding-protein-dependent transport system permease family
BsBEST3106_36870	COG1879	ABC-type sugar transport system periplasmic component
BsBEST3106_36880	COG3103	Sh3 type 3 domain protein
BsBEST3106_36900	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3106_36910	COG3527	Alpha-acetolactate decarboxylase
BsBEST3106_36920	COG0028	Belongs to the TPP enzyme family
BsBEST3106_36930	COG0583	DNA-binding transcription factor activity
BsBEST3106_36940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3106_36970	COG5337	Spore coat protein CotH
BsBEST3106_36990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3106_37010	COG0405	Gamma-glutamyltransferase
BsBEST3106_37020	COG1522	sequence-specific DNA binding
BsBEST3106_37030	COG2059	Chromate
BsBEST3106_37040	COG2059	Chromate
BsBEST3106_37060	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3106_37070	COG0583	DNA-binding transcription factor activity
BsBEST3106_37080	COG1515	deoxyribonuclease V activity
BsBEST3106_37090	COG2849	repeat protein
BsBEST3106_37100	COG5444	nuclease activity
BsBEST3106_37130	COG3878	Protein conserved in bacteria
BsBEST3106_37140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3106_37150	COG4464	protein tyrosine phosphatase activity
BsBEST3106_37160	COG0489	protein tyrosine kinase activity
BsBEST3106_37170	COG3944	biosynthesis protein
BsBEST3106_37190	COG4715	Zinc finger, swim domain protein
BsBEST3106_37200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3106_37210	COG0561	phosphatase activity
BsBEST3106_37220	COG1349	DNA-binding transcription factor activity
BsBEST3106_37230	COG0629	single-stranded DNA binding
BsBEST3106_37270	COG3764	Sortase (surface protein transpeptidase)
BsBEST3106_37290	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_37290	COG2972	Histidine kinase
BsBEST3106_37300	COG1970	mechanosensitive ion channel activity
BsBEST3106_37310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3106_37320	COG0457	Tetratricopeptide repeat
BsBEST3106_37330	COG4786	Flagellar basal body rod
BsBEST3106_37340	COG4786	Flagellar basal body rod
BsBEST3106_37350	COG1077	Cell shape determining protein MreB Mrl
BsBEST3106_37360	COG1609	Transcriptional regulator
BsBEST3106_37370	COG1846	Transcriptional regulator
BsBEST3106_37380	COG2814	Major facilitator Superfamily
BsBEST3106_37390	COG3420	alginic acid biosynthetic process
BsBEST3106_37400	COG1953	Uracil, thiamine, allantoin
BsBEST3106_37410	COG0477	Major facilitator Superfamily
BsBEST3106_37420	COG1335	isochorismatase
BsBEST3106_37440	COG0004	ammonium transporteR
BsBEST3106_37450	COG0347	Belongs to the P(II) protein family
BsBEST3106_37460	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3106_37480	COG0739	heme binding
BsBEST3106_37490	COG1247	-acetyltransferase
BsBEST3106_37510	COG2089	acid synthase
BsBEST3106_37530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3106_37540	COG0789	Transcriptional regulator
BsBEST3106_37560	COG2910	NAD(P)H-binding
BsBEST3106_37570	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3106_37580	COG0804	urea catabolic process
BsBEST3106_37590	COG0832	Belongs to the urease beta subunit family
BsBEST3106_37600	COG0831	urea catabolic process
BsBEST3106_37620	COG3237	CsbD-like
BsBEST3106_37630	COG1994	Peptidase M50
BsBEST3106_37640	COG0457	Tetratricopeptide repeat
BsBEST3106_37650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BsBEST3106_37660	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BsBEST3106_37680	COG2304	oxidoreductase activity
BsBEST3106_37690	COG2304	oxidoreductase activity
BsBEST3106_37710	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3106_37720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3106_37740	COG4836	Membrane
BsBEST3106_37760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BsBEST3106_37770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BsBEST3106_37780	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BsBEST3106_37790	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BsBEST3106_37800	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BsBEST3106_37810	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BsBEST3106_37830	COG0356	it plays a direct role in the translocation of protons across the membrane
BsBEST3106_37850	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BsBEST3106_37860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BsBEST3106_37870	COG4475	Protein of unknown function (DUF436)
BsBEST3106_37880	COG0698	ribose 5-phosphate isomerase
BsBEST3106_37890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3106_37900	COG1971	Probably functions as a manganese efflux pump
BsBEST3106_37910	COG0009	L-threonylcarbamoyladenylate synthase
BsBEST3106_37920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BsBEST3106_37960	COG2890	protein-(glutamine-N5) methyltransferase activity
BsBEST3106_37970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BsBEST3106_37980	COG0346	lactoylglutathione lyase activity
BsBEST3106_37990	COG0789	Transcriptional regulator
BsBEST3106_38000	COG0679	Auxin Efflux Carrier
BsBEST3106_38010	COG0281	malic enzyme
BsBEST3106_38030	COG1435	thymidine kinase activity
BsBEST3106_38050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BsBEST3106_38060	COG1494	fructose-1,6-bisphosphatase
BsBEST3106_38070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3106_38080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BsBEST3106_38090	COG0191	fructose-bisphosphate aldolase activity
BsBEST3106_38100	COG2204	response regulator
BsBEST3106_38110	COG4821	SIS domain
BsBEST3106_38120	COG0504	CTP synthase activity
BsBEST3106_38130	COG3343	RNA polymerase activity
BsBEST3106_38140	COG1960	acyl-CoA dehydrogenase activity
BsBEST3106_38150	COG0247	lactate metabolic process
BsBEST3106_38150	COG2181	nitrate reductase activity
BsBEST3106_38160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3106_38170	COG4294	response to UV
BsBEST3106_38190	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3106_38200	COG1132	(ABC) transporter
BsBEST3106_38210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3106_38220	COG2181	nitrate reductase activity
BsBEST3106_38230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BsBEST3106_38240	COG1140	nitrate reductase beta subunit
BsBEST3106_38250	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BsBEST3106_38260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3106_38280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3106_38290	COG2223	nitrite transmembrane transporter activity
BsBEST3106_38300	COG0018	arginyl-trna synthetase
BsBEST3106_38310	COG4506	Protein conserved in bacteria
BsBEST3106_38330	COG0535	radical SAM domain protein
BsBEST3106_38350	COG1131	(ABC) transporter
BsBEST3106_38360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3106_38370	COG0612	Peptidase, M16
BsBEST3106_38380	COG0612	Peptidase, M16
BsBEST3106_38400	COG3391	amine dehydrogenase activity
BsBEST3106_38410	COG3391	amine dehydrogenase activity
BsBEST3106_38420	COG0457	Tetratricopeptide repeat
BsBEST3106_38440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3106_38450	COG0010	Belongs to the arginase family
BsBEST3106_38460	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BsBEST3106_38470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3106_38490	COG1994	Peptidase M50
BsBEST3106_38500	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3106_38510	COG1846	Transcriptional regulator
BsBEST3106_38520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3106_38530	COG0477	Major facilitator Superfamily
BsBEST3106_38540	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3106_38550	COG3465	dGTPase activity
BsBEST3106_38560	COG1078	dGTPase activity
BsBEST3106_38570	COG4844	belongs to the
BsBEST3106_38590	COG0697	spore germination
BsBEST3106_38600	COG0095	Lipoate-protein ligase
BsBEST3106_38610	COG0583	DNA-binding transcription factor activity
BsBEST3106_38620	COG0280	phosphate acetyltransferase
BsBEST3106_38630	COG3253	May function as heme-dependent peroxidase
BsBEST3106_38640	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_38650	COG0436	Aminotransferase
BsBEST3106_38660	COG2814	Major facilitator Superfamily
BsBEST3106_38670	COG0151	Belongs to the GarS family
BsBEST3106_38680	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_38690	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3106_38700	COG0077	Prephenate dehydratase
BsBEST3106_38710	COG2814	Major facilitator Superfamily
BsBEST3106_38720	COG0833	amino acid
BsBEST3106_38730	COG4187	Peptidase family M20/M25/M40
BsBEST3106_38740	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_38750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3106_38770	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3106_38780	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3106_38790	COG1091	dTDP-4-dehydrorhamnose reductase activity
BsBEST3106_38800	COG1088	dTDP-glucose 4,6-dehydratase activity
BsBEST3106_38810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BsBEST3106_38820	COG3980	spore coat polysaccharide biosynthesis protein
BsBEST3106_38830	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BsBEST3106_38840	COG2089	acid synthase
BsBEST3106_38850	COG0456	acetyltransferase
BsBEST3106_38860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3106_38870	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3106_38880	COG0463	Glycosyl transferase, family 2
BsBEST3106_38900	COG2363	Small membrane protein
BsBEST3106_38910	COG2233	PERMEase
BsBEST3106_38930	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_38940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BsBEST3106_38950	COG1216	Glycosyl transferase, family 2
BsBEST3106_38980	COG1695	Transcriptional regulator
BsBEST3106_38990	COG0351	phosphomethylpyrimidine kinase
BsBEST3106_39010	COG1621	beta-fructofuranosidase activity
BsBEST3106_39020	COG1263	PTS System
BsBEST3106_39020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3106_39030	COG2116	formate transmembrane transporter activity
BsBEST3106_39040	COG3711	transcriptional antiterminator
BsBEST3106_39060	COG1404	Belongs to the peptidase S8 family
BsBEST3106_39070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3106_39080	COG0778	Nitroreductase
BsBEST3106_39090	COG0772	Belongs to the SEDS family
BsBEST3106_39110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3106_39120	COG1845	cytochrome c oxidase, subunit III
BsBEST3106_39130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3106_39140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3106_39150	COG2261	transglycosylase associated protein
BsBEST3106_39160	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BsBEST3106_39170	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BsBEST3106_39180	COG2246	polysaccharide biosynthetic process
BsBEST3106_39190	COG1309	transcriptional regulator
BsBEST3106_39210	COG3162	membrane
BsBEST3106_39220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3106_39230	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3106_39240	COG2837	iron assimilation
BsBEST3106_39250	COG2822	iron ion transport
BsBEST3106_39260	COG0672	)-iron permease
BsBEST3106_39270	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3106_39280	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BsBEST3106_39290	COG0583	DNA-binding transcription factor activity
BsBEST3106_39300	COG1380	Effector of murein hydrolase LrgA
BsBEST3106_39310	COG1346	cytolysis
BsBEST3106_39320	COG2814	Major facilitator Superfamily
BsBEST3106_39330	COG4895	conserved protein (DUF2196)
BsBEST3106_39340	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BsBEST3106_39350	COG0346	lactoylglutathione lyase activity
BsBEST3106_39370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3106_39380	COG1404	Belongs to the peptidase S8 family
BsBEST3106_39390	COG1263	PTS System
BsBEST3106_39390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3106_39400	COG3711	transcriptional antiterminator
BsBEST3106_39410	COG1442	glycosyl transferase family 8
BsBEST3106_39420	COG5522	Integral membrane protein (intg_mem_TP0381)
BsBEST3106_39430	COG1846	Transcriptional regulator
BsBEST3106_39440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3106_39450	COG2234	aminopeptidase activity
BsBEST3106_39460	COG2357	RelA SpoT domain protein
BsBEST3106_39470	COG1575	Belongs to the MenA family. Type 1 subfamily
BsBEST3106_39480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3106_39490	COG1696	Membrane protein involved in D-alanine export
BsBEST3106_39500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3106_39510	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BsBEST3106_39520	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3106_39530	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3106_39540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3106_39550	COG1486	melibiose metabolic process
BsBEST3106_39560	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3106_39570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3106_39580	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3106_39590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3106_39590	COG3711	transcriptional antiterminator
BsBEST3106_39610	COG2094	Belongs to the DNA glycosylase MPG family
BsBEST3106_39620	COG0753	catalase activity
BsBEST3106_39630	COG2814	Major facilitator Superfamily
BsBEST3106_39640	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3106_39650	COG1131	(ABC) transporter
BsBEST3106_39690	COG1595	DNA-templated transcription, initiation
BsBEST3106_39700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3106_39710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BsBEST3106_39720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BsBEST3106_39730	COG4988	ABC transporter
BsBEST3106_39740	COG1294	oxidase, subunit
BsBEST3106_39750	COG1271	oxidase subunit
BsBEST3106_39760	COG3493	citrate carrier protein
BsBEST3106_39770	COG0501	Belongs to the peptidase M48B family
BsBEST3106_39790	COG0726	polysaccharide deacetylase
BsBEST3106_39800	COG3842	ATPase activity
BsBEST3106_39810	COG2508	Transcriptional regulator
BsBEST3106_39820	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_39830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3106_39850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BsBEST3106_39860	COG1881	PFAM PEBP family protein
BsBEST3106_39870	COG0583	DNA-binding transcription factor activity
BsBEST3106_39890	COG4585	Histidine kinase
BsBEST3106_39900	COG2197	response regulator
BsBEST3106_39910	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3106_39930	COG4894	glucomannan catabolic process
BsBEST3106_39940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3106_39950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3106_39960	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_39970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3106_39980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3106_39990	COG2610	gluconate transmembrane transporter activity
BsBEST3106_40000	COG0500	methyltransferase
BsBEST3106_40010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3106_40040	COG0693	protein deglycase activity
BsBEST3106_40040	COG0753	catalase activity
BsBEST3106_40050	COG2851	Citrate transporter
BsBEST3106_40060	COG2273	Hydrolase Family 16
BsBEST3106_40070	COG3711	transcriptional antiterminator
BsBEST3106_40090	COG2270	Major facilitator Superfamily
BsBEST3106_40100	COG0513	Belongs to the DEAD box helicase family
BsBEST3106_40110	COG2755	lipolytic protein G-D-S-L family
BsBEST3106_40110	COG3401	FG-GAP repeat protein
BsBEST3106_40350	COG0697	spore germination
BsBEST3106_40380	COG0589	response to stress
BsBEST3106_40390	COG2723	6-phospho-beta-galactosidase activity
BsBEST3106_40400	COG2723	6-phospho-beta-galactosidase activity
BsBEST3106_40410	COG1263	PTS System
BsBEST3106_40410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3106_40410	COG2190	(PTS) system
BsBEST3106_40440	COG5444	nuclease activity
BsBEST3106_40470	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3106_40500	COG2986	histidine ammonia-lyase
BsBEST3106_40510	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BsBEST3106_40520	COG1228	amidohydrolase
BsBEST3106_40530	COG0010	Belongs to the arginase family
BsBEST3106_40540	COG0833	amino acid
BsBEST3106_40550	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BsBEST3106_40560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3106_40570	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BsBEST3106_40580	COG2390	Transcriptional regulator
BsBEST3106_40600	COG3192	ethanolamine utilization protein
BsBEST3106_40610	COG2079	MmgE PrpD family protein
BsBEST3106_40620	COG1473	amidohydrolase
BsBEST3106_40630	COG1126	abc transporter atp-binding protein
BsBEST3106_40640	COG0765	amino acid transport
BsBEST3106_40650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3106_40660	COG0456	acetyltransferase
BsBEST3106_40670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3106_40690	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BsBEST3106_40700	COG0561	phosphatase activity
BsBEST3106_40760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3106_40770	COG5294	Protein conserved in bacteria
BsBEST3106_40780	COG0577	efflux transmembrane transporter activity
BsBEST3106_40790	COG0577	efflux transmembrane transporter activity
BsBEST3106_40800	COG1136	(ABC) transporter
BsBEST3106_40810	COG1136	(ABC) transporter
BsBEST3106_40820	COG2205	protein histidine kinase activity
BsBEST3106_40830	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_40840	COG0191	fructose-bisphosphate aldolase activity
BsBEST3106_40850	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3106_40860	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3106_40870	COG0673	inositol 2-dehydrogenase activity
BsBEST3106_40880	COG2814	Major facilitator Superfamily
BsBEST3106_40890	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3106_40900	COG3962	Belongs to the TPP enzyme family
BsBEST3106_40910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3106_40920	COG3718	enzyme involved in inositol metabolism
BsBEST3106_40930	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_40940	COG1349	DNA-binding transcription factor activity
BsBEST3106_40950	COG0667	Aldo Keto reductase
BsBEST3106_40980	COG2814	Major facilitator Superfamily
BsBEST3106_40990	COG0326	Molecular chaperone. Has ATPase activity
BsBEST3106_41010	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_41020	COG1309	transcriptional regulator
BsBEST3106_41030	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3106_41040	COG0456	acetyltransferase
BsBEST3106_41050	COG2850	peptidyl-arginine hydroxylation
BsBEST3106_41060	COG2226	methyltransferase
BsBEST3106_41090	COG0367	asparagine synthase
BsBEST3106_41100	COG2814	Major facilitator Superfamily
BsBEST3106_41110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BsBEST3106_41130	COG1714	RDD family
BsBEST3106_41140	COG2311	Membrane
BsBEST3106_41150	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3106_41160	COG1309	transcriptional regulator
BsBEST3106_41170	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3106_41180	COG1846	Transcriptional regulator
BsBEST3106_41190	COG1380	Effector of murein hydrolase LrgA
BsBEST3106_41200	COG1346	cytolysis
BsBEST3106_41210	COG5039	Polysaccharide pyruvyl transferase
BsBEST3106_41220	COG1929	Belongs to the glycerate kinase type-1 family
BsBEST3106_41230	COG1802	Transcriptional regulator
BsBEST3106_41240	COG1070	Carbohydrate kinase
BsBEST3106_41250	COG2610	gluconate transmembrane transporter activity
BsBEST3106_41260	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3106_41270	COG0450	alkyl hydroperoxide reductase
BsBEST3106_41280	COG3634	alkyl hydroperoxide reductase activity
BsBEST3106_41290	COG2723	6-phospho-beta-galactosidase activity
BsBEST3106_41300	COG2190	(PTS) system
BsBEST3106_41310	COG2188	Transcriptional regulator
BsBEST3106_41340	COG1131	(ABC) transporter
BsBEST3106_41350	COG1994	Peptidase M50
BsBEST3106_41360	COG0535	radical SAM domain protein
BsBEST3106_41380	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BsBEST3106_41390	COG5293	efflux transmembrane transporter activity
BsBEST3106_41410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3106_41420	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BsBEST3106_41450	COG1063	alcohol dehydrogenase
BsBEST3106_41490	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BsBEST3106_41500	COG0456	acetyltransferase
BsBEST3106_41510	COG0457	Tetratricopeptide repeat
BsBEST3106_41520	COG0010	Belongs to the arginase family
BsBEST3106_41530	COG0833	amino acid
BsBEST3106_41540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3106_41550	COG3829	transcription factor binding
BsBEST3106_41560	COG5002	protein histidine kinase activity
BsBEST3106_41580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3106_41590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BsBEST3106_41600	COG4853	Protein conserved in bacteria
BsBEST3106_41610	COG4863	YycH protein
BsBEST3106_41620	COG5002	protein histidine kinase activity
BsBEST3106_41630	COG0745	RESPONSE REGULATOR receiver
BsBEST3106_41650	COG0346	lactoylglutathione lyase activity
BsBEST3106_41660	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3106_41690	COG3093	addiction module antidote protein HigA
BsBEST3106_41700	COG2807	transmembrane transport
BsBEST3106_41710	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3106_41720	COG0359	binds to the 23S rRNA
BsBEST3106_41730	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BsBEST3106_41740	COG4241	membrane
BsBEST3106_41760	COG5577	PFAM Coat F domain
BsBEST3106_41770	COG1733	regulation of RNA biosynthetic process
BsBEST3106_41780	COG1227	inorganic diphosphatase activity
BsBEST3106_41810	COG2271	Major facilitator Superfamily
BsBEST3106_41880	COG1131	(ABC) transporter
BsBEST3106_41900	COG4319	ketosteroid isomerase
BsBEST3106_41910	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3106_41920	COG2814	Major facilitator Superfamily
BsBEST3106_41930	COG0583	DNA-binding transcription factor activity
BsBEST3106_41940	COG2153	protein acetylation
BsBEST3106_41960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3106_41970	COG1846	Transcriptional regulator
BsBEST3106_41980	COG2153	protein acetylation
BsBEST3106_41990	COG2364	Membrane
BsBEST3106_42000	COG0456	acetyltransferase
BsBEST3106_42010	COG2315	Protein conserved in bacteria
BsBEST3106_42020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3106_42030	COG2814	Major facilitator Superfamily
BsBEST3106_42040	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3106_42050	COG0789	Transcriptional regulator
BsBEST3106_42060	COG0697	spore germination
BsBEST3106_42070	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3106_42080	COG1266	CAAX protease self-immunity
BsBEST3106_42090	COG0477	Major facilitator Superfamily
BsBEST3106_42090	COG2814	Major facilitator Superfamily
BsBEST3106_42100	COG0110	maltose O-acetyltransferase activity
BsBEST3106_42110	COG0346	lactoylglutathione lyase activity
BsBEST3106_42120	COG1609	Transcriptional regulator
BsBEST3106_42130	COG0708	Exodeoxyribonuclease III
BsBEST3106_42140	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BsBEST3106_42150	COG0629	single-stranded DNA binding
BsBEST3106_42160	COG0360	Binds together with S18 to 16S ribosomal RNA
BsBEST3106_42170	COG0012	GTP binding
BsBEST3106_42180	COG0243	molybdopterin cofactor binding
BsBEST3106_42190	COG4481	Protein conserved in bacteria
BsBEST3106_42200	COG3949	Membrane
BsBEST3106_42220	COG1475	DNA binding
BsBEST3106_42230	COG1192	Involved in chromosome partitioning
BsBEST3106_42250	COG1475	DNA binding
BsBEST3106_42260	COG0357	Ribosomal RNA small subunit methyltransferase G
BsBEST3106_42270	COG0445	tRNA wobble uridine modification
BsBEST3106_42280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BsBEST3106_42290	COG1847	R3H domain protein
BsBEST3106_42300	COG0706	membrane insertase activity
BsBEST3106_42310	COG0594	ribonuclease P activity