locus-tag	class	description
BsBEST3136_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BsBEST3136_00020	COG0592	DNA-directed DNA polymerase activity
BsBEST3136_00030	COG2501	S4 domain
BsBEST3136_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BsBEST3136_00060	COG0187	DNA topoisomerase II activity
BsBEST3136_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3136_00090	COG0516	GMP reductase activity
BsBEST3136_00090	COG0517	IMP dehydrogenase activity
BsBEST3136_00100	COG1686	Belongs to the peptidase S11 family
BsBEST3136_00110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BsBEST3136_00120	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BsBEST3136_00130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BsBEST3136_00140	COG1428	Deoxynucleoside kinase
BsBEST3136_00150	COG1428	Deoxynucleoside kinase
BsBEST3136_00160	COG1388	LysM domain
BsBEST3136_00160	COG3858	chitin binding
BsBEST3136_00170	COG1335	isochorismatase
BsBEST3136_00180	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3136_00190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BsBEST3136_00200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BsBEST3136_00210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BsBEST3136_00250	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BsBEST3136_00260	COG3853	Toxic anion resistance protein (TelA)
BsBEST3136_00270	COG1982	Orn Lys Arg decarboxylase major
BsBEST3136_00280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3136_00290	COG3870	Protein conserved in bacteria
BsBEST3136_00300	COG1728	Protein conserved in bacteria
BsBEST3136_00310	COG0470	DNA polymerase III
BsBEST3136_00320	COG1774	PSP1 C-terminal conserved region
BsBEST3136_00330	COG4467	Involved in initiation control of chromosome replication
BsBEST3136_00340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BsBEST3136_00350	COG2827	Endonuclease containing a URI domain
BsBEST3136_00360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BsBEST3136_00370	COG2002	toxin-antitoxin pair type II binding
BsBEST3136_00380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3136_00380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3136_00390	COG0084	hydrolase, TatD family'
BsBEST3136_00400	COG3584	3D domain protein
BsBEST3136_00400	COG3583	domain protein
BsBEST3136_00410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3136_00420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BsBEST3136_00440	COG4466	Protein conserved in bacteria
BsBEST3136_00460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BsBEST3136_00470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3136_00480	COG0251	oxidation-reduction process
BsBEST3136_00490	COG2088	sporulation resulting in formation of a cellular spore
BsBEST3136_00500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BsBEST3136_00510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BsBEST3136_00520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BsBEST3136_00530	COG0193	aminoacyl-tRNA hydrolase activity
BsBEST3136_00550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BsBEST3136_00560	COG2002	toxin-antitoxin pair type II binding
BsBEST3136_00570	COG2244	polysaccharide biosynthetic process
BsBEST3136_00580	COG3956	TIGRFAM MazG family protein
BsBEST3136_00590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BsBEST3136_00620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BsBEST3136_00630	COG1098	S1 RNA binding domain
BsBEST3136_00640	COG2208	phosphoserine phosphatase activity
BsBEST3136_00650	COG2304	oxidoreductase activity
BsBEST3136_00660	COG0515	serine threonine protein kinase
BsBEST3136_00670	COG0037	tRNA processing
BsBEST3136_00680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BsBEST3136_00690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3136_00700	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BsBEST3136_00710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BsBEST3136_00720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3136_00730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3136_00740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3136_00750	COG0512	Glutamine amidotransferase of anthranilate synthase
BsBEST3136_00760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3136_00770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BsBEST3136_00780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BsBEST3136_00790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BsBEST3136_00800	COG1396	sequence-specific DNA binding
BsBEST3136_00810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3136_00820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BsBEST3136_00830	COG4463	regulation of RNA biosynthetic process
BsBEST3136_00840	COG3880	PFAM UvrB UvrC protein
BsBEST3136_00850	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BsBEST3136_00860	COG0542	response to heat
BsBEST3136_00870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BsBEST3136_00880	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BsBEST3136_00890	COG4956	integral membrane protein (PIN domain superfamily)
BsBEST3136_00900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BsBEST3136_00910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BsBEST3136_00920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BsBEST3136_00930	COG1045	serine acetyltransferase
BsBEST3136_00940	COG0215	cysteine-tRNA ligase activity
BsBEST3136_00950	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BsBEST3136_00960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3136_00970	COG3688	RNA-binding protein containing a PIN domain
BsBEST3136_00980	COG1595	DNA-templated transcription, initiation
BsBEST3136_00990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3136_01000	COG0250	Participates in transcription elongation, termination and antitermination
BsBEST3136_01020	COG0081	regulation of translation
BsBEST3136_01030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BsBEST3136_01050	COG2813	Specifically methylates the guanine in position
BsBEST3136_01060	COG0085	RNA polymerase activity
BsBEST3136_01070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BsBEST3136_01080	COG1358	cellular component organization or biogenesis
BsBEST3136_01090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BsBEST3136_01100	COG0049	tRNA binding
BsBEST3136_01110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BsBEST3136_01120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BsBEST3136_01130	COG0596	Alpha beta hydrolase
BsBEST3136_01150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BsBEST3136_01160	COG0088	Forms part of the polypeptide exit tunnel
BsBEST3136_01180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BsBEST3136_01210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BsBEST3136_01220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BsBEST3136_01240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BsBEST3136_01250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BsBEST3136_01270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BsBEST3136_01290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BsBEST3136_01300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BsBEST3136_01310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BsBEST3136_01340	COG0200	Binds to the 23S rRNA
BsBEST3136_01350	COG0201	protein transport
BsBEST3136_01360	COG0563	adenylate kinase activity
BsBEST3136_01370	COG0024	Methionine aminopeptidase
BsBEST3136_01390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BsBEST3136_01400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BsBEST3136_01410	COG0202	RNA polymerase activity
BsBEST3136_01420	COG0203	ribosomal protein L17
BsBEST3136_01430	COG1122	ATPase activity
BsBEST3136_01440	COG1122	ATPase activity
BsBEST3136_01450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3136_01460	COG0101	tRNA pseudouridine synthase activity
BsBEST3136_01470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BsBEST3136_01480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BsBEST3136_01490	COG2226	methyltransferase
BsBEST3136_01510	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_01520	COG0489	protein tyrosine kinase activity
BsBEST3136_01540	COG2194	sulfuric ester hydrolase activity
BsBEST3136_01550	COG0726	polysaccharide deacetylase
BsBEST3136_01560	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3136_01580	COG0385	Bile acid
BsBEST3136_01590	COG2819	hydrolase of the alpha beta superfamily
BsBEST3136_01600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3136_01610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3136_01620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3136_01630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3136_01630	COG2207	Transcriptional regulator
BsBEST3136_01640	COG3876	Protein conserved in bacteria
BsBEST3136_01650	COG1472	Belongs to the glycosyl hydrolase 3 family
BsBEST3136_01660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3136_01670	COG1263	PTS System
BsBEST3136_01670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3136_01680	COG1737	Transcriptional regulator
BsBEST3136_01690	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BsBEST3136_01700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3136_01710	COG1683	Conserved Protein
BsBEST3136_01720	COG1595	DNA-templated transcription, initiation
BsBEST3136_01730	COG5662	AntiSigma factor
BsBEST3136_01740	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3136_01750	COG4856	YbbR-like protein
BsBEST3136_01760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3136_01770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BsBEST3136_01790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3136_01800	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3136_01810	COG2169	Transcriptional regulator
BsBEST3136_01820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3136_01830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3136_01850	COG3002	Belongs to the UPF0753 family
BsBEST3136_01860	COG0288	reversible hydration of carbon dioxide
BsBEST3136_01880	COG5609	conserved protein (DUF2294)
BsBEST3136_01890	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_01900	COG0642	Histidine kinase
BsBEST3136_01920	COG0515	serine threonine protein kinase
BsBEST3136_01950	COG1113	amino acid transport
BsBEST3136_01980	COG2602	Beta-lactamase
BsBEST3136_01990	COG2124	cytochrome p450
BsBEST3136_02010	COG0531	amino acid
BsBEST3136_02020	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3136_02030	COG2271	Major facilitator Superfamily
BsBEST3136_02050	COG0456	acetyltransferase
BsBEST3136_02050	COG1846	Transcriptional regulator
BsBEST3136_02060	COG2271	Major facilitator Superfamily
BsBEST3136_02070	COG2271	Major facilitator Superfamily
BsBEST3136_02100	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_02110	COG0697	spore germination
BsBEST3136_02120	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3136_02120	COG2207	Transcriptional regulator
BsBEST3136_02180	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BsBEST3136_02190	COG3591	Belongs to the peptidase S1B family
BsBEST3136_02210	COG0596	Alpha beta hydrolase
BsBEST3136_02220	COG1183	phosphatidylcholine synthase activity
BsBEST3136_02230	COG0586	Pfam SNARE associated Golgi protein
BsBEST3136_02240	COG0688	phosphatidylethanolamine metabolic process
BsBEST3136_02260	COG2312	Erythromycin esterase
BsBEST3136_02270	COG2207	Transcriptional regulator
BsBEST3136_02280	COG1054	Belongs to the UPF0176 family
BsBEST3136_02290	COG1301	dicarboxylic acid transport
BsBEST3136_02300	COG1263	PTS System
BsBEST3136_02300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3136_02300	COG2190	(PTS) system
BsBEST3136_02310	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3136_02320	COG2188	Transcriptional regulator
BsBEST3136_02340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3136_02350	COG0833	amino acid
BsBEST3136_02360	COG2040	homocysteine
BsBEST3136_02370	COG1115	amino acid carrier protein
BsBEST3136_02380	COG1115	amino acid carrier protein
BsBEST3136_02390	COG2066	Belongs to the glutaminase family
BsBEST3136_02400	COG4191	Histidine kinase
BsBEST3136_02410	COG0784	Response regulator, receiver
BsBEST3136_02420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3136_02430	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_02440	COG2271	Major facilitator Superfamily
BsBEST3136_02450	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3136_02460	COG2186	Transcriptional regulator
BsBEST3136_02470	COG2721	sulfolactate sulfo-lyase activity
BsBEST3136_02480	COG3173	Aminoglycoside phosphotransferase
BsBEST3136_02500	COG0697	spore germination
BsBEST3136_02510	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_02520	COG2205	protein histidine kinase activity
BsBEST3136_02530	COG1131	(ABC) transporter
BsBEST3136_02560	COG3773	Cell wall hydrolase
BsBEST3136_02570	COG2304	oxidoreductase activity
BsBEST3136_02580	COG3540	Alkaline phosphatase
BsBEST3136_02590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3136_02600	COG0805	protein transport
BsBEST3136_02610	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BsBEST3136_02620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3136_02630	COG0477	Major facilitator Superfamily
BsBEST3136_02640	COG1309	transcriptional regulator
BsBEST3136_02650	COG0252	asparaginase activity
BsBEST3136_02660	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3136_02670	COG1714	RDD family
BsBEST3136_02680	COG1405	negative regulation of cell septum assembly
BsBEST3136_02680	COG3012	SEC-C Motif Domain Protein
BsBEST3136_02690	COG3290	protein histidine kinase activity
BsBEST3136_02700	COG3279	Response regulator of the LytR AlgR family
BsBEST3136_02710	COG4555	ABC transporter
BsBEST3136_02720	COG4555	ABC transporter
BsBEST3136_02730	COG1668	transmembrane transport
BsBEST3136_02740	COG0667	Aldo Keto reductase
BsBEST3136_02760	COG1595	DNA-templated transcription, initiation
BsBEST3136_02770	COG1595	DNA-templated transcription, initiation
BsBEST3136_02780	COG1876	peptidase activity
BsBEST3136_02790	COG0457	Tetratricopeptide repeat
BsBEST3136_02800	COG0457	Tetratricopeptide repeat
BsBEST3136_02810	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_02820	COG0366	Alpha amylase catalytic
BsBEST3136_02830	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3136_02840	COG1121	(ABC) transporter
BsBEST3136_02850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3136_02860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3136_02870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3136_02880	COG2310	stress, protein
BsBEST3136_02890	COG2310	stress, protein
BsBEST3136_02900	COG2310	stress, protein
BsBEST3136_02910	COG0861	Integral membrane protein TerC family
BsBEST3136_02930	COG3853	Toxic anion resistance protein (TelA)
BsBEST3136_02940	COG0477	Major facilitator Superfamily
BsBEST3136_02950	COG2814	Major facilitator Superfamily
BsBEST3136_02960	COG0640	Transcriptional regulator
BsBEST3136_02970	COG0517	IMP dehydrogenase activity
BsBEST3136_02970	COG4175	Glycine betaine
BsBEST3136_02980	COG4176	ABC-type proline glycine betaine transport system permease component
BsBEST3136_02990	COG2113	Glycine betaine
BsBEST3136_03000	COG1473	amidohydrolase
BsBEST3136_03010	COG1288	antiporter activity
BsBEST3136_03030	COG0366	Alpha amylase catalytic
BsBEST3136_03040	COG0366	Alpha amylase catalytic
BsBEST3136_03050	COG0039	L-malate dehydrogenase activity
BsBEST3136_03060	COG1620	l-lactate permease
BsBEST3136_03070	COG1620	l-lactate permease
BsBEST3136_03080	COG3403	YqcI/YcgG family
BsBEST3136_03100	COG1113	amino acid transport
BsBEST3136_03110	COG1113	amino acid transport
BsBEST3136_03120	COG3665	Urea carboxylase-associated protein
BsBEST3136_03130	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BsBEST3136_03140	COG1660	Displays ATPase and GTPase activities
BsBEST3136_03150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BsBEST3136_03160	COG2226	methyltransferase
BsBEST3136_03170	COG0583	DNA-binding transcription factor activity
BsBEST3136_03180	COG3458	cephalosporin-C deacetylase activity
BsBEST3136_03190	COG3541	Predicted nucleotidyltransferase
BsBEST3136_03200	COG0506	proline dehydrogenase activity
BsBEST3136_03210	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_03220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3136_03230	COG2508	Transcriptional regulator
BsBEST3136_03240	COG3689	TIGRFAM TIGR03943 family protein
BsBEST3136_03250	COG0701	Predicted permease
BsBEST3136_03260	COG2267	carboxylic ester hydrolase activity
BsBEST3136_03270	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3136_03280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3136_03280	COG1587	Uroporphyrinogen-III synthase
BsBEST3136_03290	COG2146	nitrite reductase [NAD(P)H] activity
BsBEST3136_03300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3136_03310	COG0243	molybdopterin cofactor binding
BsBEST3136_03320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3136_03330	COG2223	nitrite transmembrane transporter activity
BsBEST3136_03340	COG1469	GTP cyclohydrolase I activity
BsBEST3136_03350	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3136_03360	COG0523	cobalamin synthesis protein
BsBEST3136_03370	COG0765	amino acid transport
BsBEST3136_03380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3136_03400	COG1714	RDD family
BsBEST3136_03420	COG2723	6-phospho-beta-galactosidase activity
BsBEST3136_03440	COG3209	COG3209 Rhs family protein
BsBEST3136_03450	COG0840	transmembrane signaling receptor activity
BsBEST3136_03450	COG3290	protein histidine kinase activity
BsBEST3136_03460	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BsBEST3136_03470	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BsBEST3136_03480	COG1733	regulation of RNA biosynthetic process
BsBEST3136_03490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_03500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_03510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_03520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_03530	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BsBEST3136_03540	COG2814	Major facilitator Superfamily
BsBEST3136_03560	COG0697	spore germination
BsBEST3136_03570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3136_03600	COG2364	Membrane
BsBEST3136_03610	COG1126	abc transporter atp-binding protein
BsBEST3136_03620	COG0765	amino acid transport
BsBEST3136_03630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3136_03640	COG0583	DNA-binding transcription factor activity
BsBEST3136_03650	COG0163	prenyltransferase activity
BsBEST3136_03660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BsBEST3136_03690	COG0596	Alpha beta hydrolase
BsBEST3136_03700	COG3104	oligopeptide transport
BsBEST3136_03710	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3136_03730	COG0697	spore germination
BsBEST3136_03750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3136_03760	COG1136	(ABC) transporter
BsBEST3136_03770	COG0577	efflux transmembrane transporter activity
BsBEST3136_03780	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_03790	COG3850	Histidine kinase
BsBEST3136_03790	COG5002	protein histidine kinase activity
BsBEST3136_03800	COG0457	Tetratricopeptide repeat
BsBEST3136_03820	COG0527	aspartate kinase activity
BsBEST3136_03830	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3136_03840	COG4605	iron ion homeostasis
BsBEST3136_03850	COG4604	ABC transporter, ATP-binding protein
BsBEST3136_03860	COG4607	ABC-type enterochelin transport system periplasmic component
BsBEST3136_03870	COG2814	Major facilitator Superfamily
BsBEST3136_03880	COG1309	transcriptional regulator
BsBEST3136_03890	COG0778	Nitroreductase
BsBEST3136_03900	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3136_03910	COG0640	Transcriptional regulator
BsBEST3136_03920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3136_03930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BsBEST3136_03940	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_03950	COG4975	Glucose uptake
BsBEST3136_03960	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_03970	COG4549	nuclear export factor GLE1
BsBEST3136_03980	COG1276	copper resistance
BsBEST3136_03980	COG2372	response to copper ion
BsBEST3136_03990	COG1349	DNA-binding transcription factor activity
BsBEST3136_04010	COG2213	PTS system mannitol-specific
BsBEST3136_04020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3136_04030	COG0246	Mannitol dehydrogenase
BsBEST3136_04040	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3136_04060	COG0681	Belongs to the peptidase S26 family
BsBEST3136_04070	COG0412	Dienelactone hydrolase
BsBEST3136_04080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3136_04100	COG0561	phosphatase activity
BsBEST3136_04110	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3136_04120	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3136_04130	COG4336	lyase activity
BsBEST3136_04140	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3136_04150	COG1984	allophanate hydrolase subunit 2
BsBEST3136_04160	COG1414	Transcriptional regulator
BsBEST3136_04170	COG2755	lipolytic protein G-D-S-L family
BsBEST3136_04190	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3136_04200	COG0768	penicillin binding
BsBEST3136_04210	COG4989	oxidoreductase activity
BsBEST3136_04220	COG3711	transcriptional antiterminator
BsBEST3136_04230	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3136_04240	COG2226	methyltransferase
BsBEST3136_04250	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_04260	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3136_04270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3136_04280	COG3871	stress protein (general stress protein 26)
BsBEST3136_04300	COG2814	Major facilitator Superfamily
BsBEST3136_04310	COG1522	sequence-specific DNA binding
BsBEST3136_04320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3136_04320	COG0551	DNA topoisomerase type I activity
BsBEST3136_04330	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BsBEST3136_04340	COG3706	GGDEF domain
BsBEST3136_04350	COG5298	Protein conserved in bacteria
BsBEST3136_04360	COG1215	transferase activity, transferring glycosyl groups
BsBEST3136_04380	COG0531	amino acid
BsBEST3136_04390	COG0494	nUDIX hydrolase
BsBEST3136_04400	COG0028	Belongs to the TPP enzyme family
BsBEST3136_04430	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3136_04440	COG2261	transglycosylase associated protein
BsBEST3136_04450	COG4876	unkown
BsBEST3136_04460	COG2217	Heavy metal translocating P-type atpase
BsBEST3136_04470	COG3729	General stress protein
BsBEST3136_04480	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3136_04490	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3136_04500	COG3546	catalase activity
BsBEST3136_04510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BsBEST3136_04520	COG3290	protein histidine kinase activity
BsBEST3136_04530	COG4565	transcriptional regulatory protein
BsBEST3136_04540	COG1301	dicarboxylic acid transport
BsBEST3136_04550	COG0628	permease
BsBEST3136_04570	COG1131	(ABC) transporter
BsBEST3136_04580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3136_04600	COG1960	acyl-CoA dehydrogenase activity
BsBEST3136_04630	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3136_04640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_04650	COG1181	Belongs to the D-alanine--D-alanine ligase family
BsBEST3136_04660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BsBEST3136_04670	COG0513	Belongs to the DEAD box helicase family
BsBEST3136_04680	COG3402	PFAM membrane-flanked domain
BsBEST3136_04690	COG3428	Bacterial PH domain
BsBEST3136_04700	COG0705	Rhomboid family
BsBEST3136_04710	COG0736	holo-[acyl-carrier-protein] synthase activity
BsBEST3136_04720	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BsBEST3136_04730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3136_04740	COG0864	Transcriptional regulator
BsBEST3136_04750	COG2337	Toxic component of a toxin-antitoxin (TA) module
BsBEST3136_04760	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3136_04770	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3136_04780	COG2172	sigma factor antagonist activity
BsBEST3136_04790	COG2208	phosphoserine phosphatase activity
BsBEST3136_04800	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3136_04810	COG2172	sigma factor antagonist activity
BsBEST3136_04820	COG1191	sigma factor activity
BsBEST3136_04830	COG2208	phosphoserine phosphatase activity
BsBEST3136_04860	COG1673	EVE domain
BsBEST3136_04870	COG1846	Transcriptional regulator
BsBEST3136_04880	COG2183	response to ionizing radiation
BsBEST3136_04890	COG3091	SprT-like family
BsBEST3136_04900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3136_04910	COG1522	sequence-specific DNA binding
BsBEST3136_04920	COG1522	sequence-specific DNA binding
BsBEST3136_04930	COG1335	isochorismatase
BsBEST3136_04940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3136_04950	COG2814	Major facilitator Superfamily
BsBEST3136_05000	COG0693	protein deglycase activity
BsBEST3136_05010	COG1278	Cold shock
BsBEST3136_05020	COG1329	Transcriptional regulator
BsBEST3136_05030	COG0697	spore germination
BsBEST3136_05040	COG2207	Transcriptional regulator
BsBEST3136_05040	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3136_05050	COG0697	spore germination
BsBEST3136_05060	COG2207	Transcriptional regulator
BsBEST3136_05060	COG3708	Transcriptional regulator
BsBEST3136_05070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3136_05080	COG0477	Major facilitator Superfamily
BsBEST3136_05100	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BsBEST3136_05120	COG0697	spore germination
BsBEST3136_05130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3136_05140	COG2030	dehydratase
BsBEST3136_05150	COG3545	Serine hydrolase
BsBEST3136_05160	COG1733	regulation of RNA biosynthetic process
BsBEST3136_05170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3136_05180	COG1733	regulation of RNA biosynthetic process
BsBEST3136_05190	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3136_05200	COG2814	Major facilitator Superfamily
BsBEST3136_05210	COG1309	transcriptional regulator
BsBEST3136_05230	COG0640	Transcriptional regulator
BsBEST3136_05240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3136_05250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3136_05260	COG0697	spore germination
BsBEST3136_05270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3136_05280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3136_05290	COG0640	Transcriptional regulator
BsBEST3136_05300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3136_05320	COG4585	Histidine kinase
BsBEST3136_05330	COG2197	response regulator
BsBEST3136_05340	COG2409	Drug exporters of the RND superfamily
BsBEST3136_05350	COG0596	Alpha beta hydrolase
BsBEST3136_05360	COG1811	Na channel or pump
BsBEST3136_05370	COG0789	Transcriptional regulator
BsBEST3136_05370	COG4978	Transcriptional regulator
BsBEST3136_05380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3136_05390	COG0778	Nitroreductase
BsBEST3136_05400	COG0346	lactoylglutathione lyase activity
BsBEST3136_05410	COG2259	Doxx family
BsBEST3136_05420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_05450	COG2323	membrane
BsBEST3136_05460	COG2323	membrane
BsBEST3136_05470	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3136_05500	COG1309	transcriptional regulator
BsBEST3136_05520	COG0456	acetyltransferase
BsBEST3136_05530	COG0488	(ABC) transporter
BsBEST3136_05540	COG1113	amino acid transport
BsBEST3136_05550	COG2318	DinB family
BsBEST3136_05560	COG1846	Transcriptional regulator
BsBEST3136_05570	COG1033	growth of symbiont in host cell
BsBEST3136_05570	COG2409	Drug exporters of the RND superfamily
BsBEST3136_05580	COG0778	Nitroreductase
BsBEST3136_05590	COG1846	Transcriptional regulator
BsBEST3136_05600	COG2814	Major facilitator Superfamily
BsBEST3136_05610	COG0730	response to heat
BsBEST3136_05620	COG1802	Transcriptional regulator
BsBEST3136_05630	COG3858	chitin binding
BsBEST3136_05630	COG1388	LysM domain
BsBEST3136_05640	COG1819	glycosyl
BsBEST3136_05660	COG1785	Belongs to the alkaline phosphatase family
BsBEST3136_05670	COG5646	InterPro IPR014922
BsBEST3136_05690	COG0454	-acetyltransferase
BsBEST3136_05700	COG1078	dGTPase activity
BsBEST3136_05710	COG1388	LysM domain
BsBEST3136_05720	COG2814	Major facilitator Superfamily
BsBEST3136_05730	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3136_05740	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3136_05750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3136_05760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3136_05770	COG2723	6-phospho-beta-galactosidase activity
BsBEST3136_05780	COG2188	Transcriptional regulator
BsBEST3136_05790	COG1940	carbohydrate kinase activity
BsBEST3136_05800	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3136_05810	COG4124	Belongs to the glycosyl hydrolase 26 family
BsBEST3136_05840	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BsBEST3136_05850	COG0802	atpase or kinase
BsBEST3136_05860	COG1214	PFAM Peptidase M22, glycoprotease
BsBEST3136_05870	COG0456	acetyltransferase
BsBEST3136_05880	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BsBEST3136_05890	COG0488	(ABC) transporter
BsBEST3136_05900	COG0315	cyclic pyranopterin monophosphate synthase activity
BsBEST3136_05910	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BsBEST3136_05920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3136_05930	COG0805	protein transport
BsBEST3136_05950	COG1266	CAAX protease self-immunity
BsBEST3136_05970	COG0459	protein refolding
BsBEST3136_06000	COG3378	Phage plasmid primase P4 family
BsBEST3136_06030	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3136_06040	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3136_06070	COG1401	restriction endodeoxyribonuclease activity
BsBEST3136_06120	COG1073	alpha beta
BsBEST3136_06130	COG0457	Tetratricopeptide repeat
BsBEST3136_06140	COG1063	alcohol dehydrogenase
BsBEST3136_06150	COG2211	Major facilitator Superfamily
BsBEST3136_06160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3136_06170	COG1842	Phage shock protein A
BsBEST3136_06180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3136_06190	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BsBEST3136_06200	COG4260	virion core protein, lumpy skin disease virus
BsBEST3136_06220	COG2814	Major facilitator Superfamily
BsBEST3136_06230	COG1063	alcohol dehydrogenase
BsBEST3136_06240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BsBEST3136_06250	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3136_06280	COG2267	carboxylic ester hydrolase activity
BsBEST3136_06300	COG2132	Multicopper oxidase
BsBEST3136_06310	COG1113	amino acid transport
BsBEST3136_06320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3136_06330	COG0714	Associated with various cellular activities
BsBEST3136_06340	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BsBEST3136_06350	COG1305	Transglutaminase-like
BsBEST3136_06360	COG0519	Catalyzes the synthesis of GMP from XMP
BsBEST3136_06360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BsBEST3136_06370	COG2252	PERMEase
BsBEST3136_06380	COG3064	Membrane
BsBEST3136_06400	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BsBEST3136_06420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BsBEST3136_06430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BsBEST3136_06440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BsBEST3136_06450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BsBEST3136_06460	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3136_06470	COG0047	phosphoribosylformylglycinamidine synthase activity
BsBEST3136_06480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3136_06490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BsBEST3136_06500	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BsBEST3136_06510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BsBEST3136_06520	COG0138	bifunctional purine biosynthesis protein purh
BsBEST3136_06530	COG0151	Belongs to the GarS family
BsBEST3136_06540	COG1522	sequence-specific DNA binding
BsBEST3136_06550	COG0531	amino acid
BsBEST3136_06560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3136_06570	COG1470	cell adhesion involved in biofilm formation
BsBEST3136_06580	COG4496	protein, YerC YecD
BsBEST3136_06590	COG0069	glutamate synthase activity
BsBEST3136_06600	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BsBEST3136_06610	COG0210	DNA helicase
BsBEST3136_06620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BsBEST3136_06630	COG4851	CamS sex pheromone cAM373 precursor
BsBEST3136_06650	COG2801	Transposase and inactivated derivatives
BsBEST3136_06660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3136_06670	COG1285	pathogenesis
BsBEST3136_06680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3136_06690	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3136_06700	COG0154	amidase activity
BsBEST3136_06710	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3136_06720	COG1309	transcriptional regulator
BsBEST3136_06730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BsBEST3136_06740	COG1597	lipid kinase activity
BsBEST3136_06750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3136_06800	COG5444	nuclease activity
BsBEST3136_06810	COG3391	amine dehydrogenase activity
BsBEST3136_06820	COG3391	amine dehydrogenase activity
BsBEST3136_06830	COG0457	Tetratricopeptide repeat
BsBEST3136_06850	COG0217	transcriptional regulatory protein
BsBEST3136_06870	COG1309	transcriptional regulator
BsBEST3136_06910	COG3546	catalase activity
BsBEST3136_06920	COG0454	-acetyltransferase
BsBEST3136_06940	COG5578	integral membrane protein
BsBEST3136_06950	COG2972	Histidine kinase
BsBEST3136_06960	COG2207	Transcriptional regulator
BsBEST3136_06960	COG4753	response regulator
BsBEST3136_06970	COG2207	Transcriptional regulator
BsBEST3136_06970	COG4753	response regulator
BsBEST3136_06980	COG1653	transport
BsBEST3136_06990	COG1175	transmembrane transport
BsBEST3136_07000	COG0395	ABC-type sugar transport system, permease component
BsBEST3136_07010	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3136_07020	COG2207	Transcriptional regulator
BsBEST3136_07030	COG2755	lipolytic protein G-D-S-L family
BsBEST3136_07050	COG5578	integral membrane protein
BsBEST3136_07060	COG3401	FG-GAP repeat protein
BsBEST3136_07070	COG3401	FG-GAP repeat protein
BsBEST3136_07080	COG2755	lipolytic protein G-D-S-L family
BsBEST3136_07090	COG1874	Beta-galactosidase
BsBEST3136_07100	COG1874	Beta-galactosidase
BsBEST3136_07110	COG1874	Beta-galactosidase
BsBEST3136_07150	COG1653	transport
BsBEST3136_07160	COG4209	transmembrane transport
BsBEST3136_07170	COG0395	ABC-type sugar transport system, permease component
BsBEST3136_07180	COG1486	melibiose metabolic process
BsBEST3136_07190	COG2323	membrane
BsBEST3136_07200	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3136_07210	COG0346	lactoylglutathione lyase activity
BsBEST3136_07240	COG5583	Uncharacterized small protein (DUF2292)
BsBEST3136_07250	COG0670	Belongs to the BI1 family
BsBEST3136_07260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3136_07280	COG3328	transposase activity
BsBEST3136_07300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3136_07300	COG2124	cytochrome p450
BsBEST3136_07310	COG1368	sulfuric ester hydrolase activity
BsBEST3136_07320	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BsBEST3136_07330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3136_07340	COG1442	glycosyl transferase family 8
BsBEST3136_07350	COG1216	Glycosyl transferase, family 2
BsBEST3136_07360	COG1442	glycosyl transferase family 8
BsBEST3136_07370	COG2223	nitrite transmembrane transporter activity
BsBEST3136_07380	COG1011	Hydrolase
BsBEST3136_07390	COG0531	amino acid
BsBEST3136_07400	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_07410	COG0840	transmembrane signaling receptor activity
BsBEST3136_07420	COG0488	(ABC) transporter
BsBEST3136_07440	COG0789	Transcriptional regulator
BsBEST3136_07450	COG2814	Major facilitator Superfamily
BsBEST3136_07470	COG0488	(ABC) transporter
BsBEST3136_07480	COG0513	Belongs to the DEAD box helicase family
BsBEST3136_07490	COG0456	acetyltransferase
BsBEST3136_07500	COG2130	NADP-dependent
BsBEST3136_07520	COG2211	Major facilitator Superfamily
BsBEST3136_07530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BsBEST3136_07540	COG1120	ATPase activity
BsBEST3136_07550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3136_07560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3136_07570	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3136_07600	COG3866	Pectate lyase
BsBEST3136_07610	COG0471	metal ion transport
BsBEST3136_07620	COG3290	protein histidine kinase activity
BsBEST3136_07630	COG4565	transcriptional regulatory protein
BsBEST3136_07640	COG3181	Tripartite tricarboxylate transporter family receptor
BsBEST3136_07650	COG2851	Citrate transporter
BsBEST3136_07660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3136_07670	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BsBEST3136_07680	COG1254	Belongs to the acylphosphatase family
BsBEST3136_07690	COG2258	MOSC domain
BsBEST3136_07730	COG0024	Methionine aminopeptidase
BsBEST3136_07740	COG1263	PTS System
BsBEST3136_07740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3136_07750	COG1368	sulfuric ester hydrolase activity
BsBEST3136_07770	COG1115	amino acid carrier protein
BsBEST3136_07780	COG0531	amino acid
BsBEST3136_07810	COG0697	spore germination
BsBEST3136_07820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3136_07820	COG1263	PTS System
BsBEST3136_07830	COG0366	Alpha amylase catalytic
BsBEST3136_07840	COG2188	Transcriptional regulator
BsBEST3136_07850	COG0778	Nitroreductase
BsBEST3136_07860	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3136_07870	COG0693	protein deglycase activity
BsBEST3136_07880	COG2814	Major facilitator Superfamily
BsBEST3136_07890	COG4840	Belongs to the UPF0435 family
BsBEST3136_07900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3136_07910	COG4980	gas vesicle protein
BsBEST3136_07920	COG1295	ribonuclease BN
BsBEST3136_07930	COG0477	Major facilitator Superfamily
BsBEST3136_07940	COG0387	Pfam Sodium calcium exchanger
BsBEST3136_07960	COG0668	transmembrane transport
BsBEST3136_07970	COG0535	radical SAM domain protein
BsBEST3136_07990	COG0726	polysaccharide deacetylase
BsBEST3136_08000	COG2084	Dehydrogenase
BsBEST3136_08010	COG0598	Magnesium transport protein CorA
BsBEST3136_08020	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3136_08030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3136_08050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3136_08060	COG4637	Psort location Cytoplasmic, score
BsBEST3136_08080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3136_08090	COG0022	dehydrogenase e1 component
BsBEST3136_08100	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3136_08110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3136_08120	COG3284	Transcriptional regulator
BsBEST3136_08140	COG1742	UPF0060 membrane protein
BsBEST3136_08190	COG4842	Belongs to the WXG100 family
BsBEST3136_08200	COG1486	melibiose metabolic process
BsBEST3136_08210	COG1737	Transcriptional regulator
BsBEST3136_08220	COG1263	PTS System
BsBEST3136_08220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3136_08230	COG1132	(ABC) transporter
BsBEST3136_08240	COG1132	(ABC) transporter
BsBEST3136_08250	COG2259	Doxx family
BsBEST3136_08260	COG2514	catechol 2,3-dioxygenase activity
BsBEST3136_08270	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3136_08270	COG4977	sequence-specific DNA binding
BsBEST3136_08280	COG2814	Major facilitator Superfamily
BsBEST3136_08290	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3136_08300	COG0673	inositol 2-dehydrogenase activity
BsBEST3136_08310	COG4585	Histidine kinase
BsBEST3136_08320	COG2197	response regulator
BsBEST3136_08330	COG1131	(ABC) transporter
BsBEST3136_08340	COG0842	Transport permease protein
BsBEST3136_08340	COG1511	domain protein
BsBEST3136_08350	COG0842	Transport permease protein
BsBEST3136_08360	COG1695	Transcriptional regulator
BsBEST3136_08370	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3136_08380	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BsBEST3136_08390	COG1309	transcriptional regulator
BsBEST3136_08400	COG2814	Major facilitator Superfamily
BsBEST3136_08410	COG2318	DinB family
BsBEST3136_08420	COG2814	Major facilitator Superfamily
BsBEST3136_08430	COG1846	Transcriptional regulator
BsBEST3136_08440	COG0392	lysyltransferase activity
BsBEST3136_08440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BsBEST3136_08450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3136_08470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3136_08480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3136_08490	COG0384	phenazine biosynthesis protein PhzF
BsBEST3136_08500	COG0778	Nitroreductase
BsBEST3136_08520	COG1090	epimerase
BsBEST3136_08530	COG2137	regulation of response to DNA damage stimulus
BsBEST3136_08550	COG2814	Major facilitator Superfamily
BsBEST3136_08580	COG3103	Sh3 type 3 domain protein
BsBEST3136_08590	COG5658	integral membrane protein
BsBEST3136_08600	COG0596	Alpha beta hydrolase
BsBEST3136_08610	COG0463	Glycosyl transferase, family 2
BsBEST3136_08620	COG4485	Bacterial membrane protein, YfhO
BsBEST3136_08630	COG1988	membrane-bound metal-dependent
BsBEST3136_08640	COG1194	a g-specific adenine glycosylase
BsBEST3136_08660	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_08690	COG3557	Belongs to the UPF0374 family
BsBEST3136_08700	COG1132	(ABC) transporter
BsBEST3136_08710	COG4129	membrane
BsBEST3136_08720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3136_08730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BsBEST3136_08740	COG0735	belongs to the Fur family
BsBEST3136_08770	COG4326	sporulation control protein
BsBEST3136_08790	COG3340	Belongs to the peptidase S51 family
BsBEST3136_08800	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BsBEST3136_08810	COG0277	FAD linked oxidase domain protein
BsBEST3136_08830	COG0753	catalase activity
BsBEST3136_08840	COG1116	anion transmembrane transporter activity
BsBEST3136_08850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3136_08860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3136_08870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3136_08890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BsBEST3136_08910	COG1476	TRANSCRIPTIONal
BsBEST3136_08920	COG3382	B3 4 domain protein
BsBEST3136_08930	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BsBEST3136_08950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BsBEST3136_08960	COG0789	Transcriptional regulator
BsBEST3136_08970	COG1664	Polymer-forming cytoskeletal
BsBEST3136_08980	COG1664	Polymer-forming cytoskeletal
BsBEST3136_08990	COG2766	serine protein kinase
BsBEST3136_09000	COG2718	Belongs to the UPF0229 family
BsBEST3136_09010	COG1846	Transcriptional regulator
BsBEST3136_09020	COG1566	PFAM secretion protein HlyD family protein
BsBEST3136_09030	COG2814	Major facilitator Superfamily
BsBEST3136_09040	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3136_09070	COG1725	Transcriptional regulator
BsBEST3136_09080	COG1131	(ABC) transporter
BsBEST3136_09090	COG1131	(ABC) transporter
BsBEST3136_09100	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3136_09110	COG1278	Cold shock
BsBEST3136_09120	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3136_09130	COG3706	GGDEF domain
BsBEST3136_09140	COG1823	symporter activity
BsBEST3136_09180	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3136_09180	COG1525	nuclease
BsBEST3136_09180	COG4085	toxin activity
BsBEST3136_09190	COG3764	Sortase (surface protein transpeptidase)
BsBEST3136_09200	COG0564	pseudouridine synthase activity
BsBEST3136_09220	COG0517	IMP dehydrogenase activity
BsBEST3136_09230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3136_09240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3136_09240	COG3153	acetyltransferase
BsBEST3136_09260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3136_09270	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BsBEST3136_09280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BsBEST3136_09290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BsBEST3136_09300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BsBEST3136_09310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3136_09320	COG2203	Gaf domain
BsBEST3136_09320	COG4585	Histidine kinase
BsBEST3136_09330	COG2197	response regulator
BsBEST3136_09340	COG0431	NADPH-dependent FMN reductase
BsBEST3136_09370	COG0791	NLP P60 protein
BsBEST3136_09370	COG1388	LysM domain
BsBEST3136_09380	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3136_09390	COG0668	transmembrane transport
BsBEST3136_09400	COG2719	SpoVR family
BsBEST3136_09410	COG1785	Belongs to the alkaline phosphatase family
BsBEST3136_09420	COG0791	NLP P60 protein
BsBEST3136_09420	COG1388	LysM domain
BsBEST3136_09430	COG0583	DNA-binding transcription factor activity
BsBEST3136_09440	COG0372	Belongs to the citrate synthase family
BsBEST3136_09450	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_09460	COG0531	amino acid
BsBEST3136_09470	COG0733	neurotransmitter:sodium symporter activity
BsBEST3136_09480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3136_09490	COG0456	acetyltransferase
BsBEST3136_09520	COG1595	DNA-templated transcription, initiation
BsBEST3136_09530	COG0667	Aldo Keto reductase
BsBEST3136_09540	COG0204	Acyl-transferase
BsBEST3136_09550	COG1253	flavin adenine dinucleotide binding
BsBEST3136_09560	COG0789	Transcriptional regulator
BsBEST3136_09570	COG0436	Aminotransferase
BsBEST3136_09580	COG0436	Aminotransferase
BsBEST3136_09590	COG1253	flavin adenine dinucleotide binding
BsBEST3136_09600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3136_09610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3136_09620	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3136_09640	COG0668	transmembrane transport
BsBEST3136_09650	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BsBEST3136_09660	COG0726	polysaccharide deacetylase
BsBEST3136_09670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3136_09680	COG1757	Na H antiporter
BsBEST3136_09690	COG0589	response to stress
BsBEST3136_09710	COG1132	(ABC) transporter
BsBEST3136_09720	COG1132	(ABC) transporter
BsBEST3136_09730	COG0702	epimerase
BsBEST3136_09760	COG0189	ligase activity
BsBEST3136_09770	COG0189	ligase activity
BsBEST3136_09780	COG4399	Belongs to the UPF0754 family
BsBEST3136_09790	COG3679	Belongs to the UPF0342 family
BsBEST3136_09800	COG4335	DNA alkylation repair
BsBEST3136_09810	COG4335	DNA alkylation repair
BsBEST3136_09820	COG0561	phosphatase activity
BsBEST3136_09830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3136_09840	COG0475	glutathione-regulated potassium exporter activity
BsBEST3136_09850	COG0490	domain, Protein
BsBEST3136_09870	COG1024	Enoyl-CoA hydratase
BsBEST3136_09890	COG4152	abc transporter atp-binding protein
BsBEST3136_09900	COG1668	transmembrane transport
BsBEST3136_09910	COG0420	3'-5' exonuclease activity
BsBEST3136_09920	COG4717	serine-type aminopeptidase activity
BsBEST3136_09930	COG3481	metal-dependent phosphohydrolase, HD sub domain
BsBEST3136_09950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3136_09980	COG1846	Transcriptional regulator
BsBEST3136_09990	COG4980	gas vesicle protein
BsBEST3136_10010	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BsBEST3136_10020	COG0537	adenosine 5'-monophosphoramidase activity
BsBEST3136_10030	COG1131	(ABC) transporter
BsBEST3136_10040	COG4473	ABC transporter
BsBEST3136_10060	COG1473	amidohydrolase
BsBEST3136_10070	COG3069	C4-dicarboxylate transmembrane transporter activity
BsBEST3136_10090	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3136_10100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3136_10110	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BsBEST3136_10120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BsBEST3136_10130	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BsBEST3136_10140	COG1309	transcriptional regulator
BsBEST3136_10150	COG1511	domain protein
BsBEST3136_10160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3136_10170	COG4377	Putative membrane peptidase family (DUF2324)
BsBEST3136_10190	COG1363	Peptidase, m42
BsBEST3136_10200	COG4405	Protein conserved in bacteria
BsBEST3136_10210	COG1301	dicarboxylic acid transport
BsBEST3136_10220	COG1234	tRNA 3'-trailer cleavage
BsBEST3136_10230	COG0095	Lipoate-protein ligase
BsBEST3136_10240	COG0702	epimerase
BsBEST3136_10250	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3136_10270	COG0501	Belongs to the peptidase M48B family
BsBEST3136_10290	COG0456	acetyltransferase
BsBEST3136_10300	COG0604	alcohol dehydrogenase
BsBEST3136_10310	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3136_10320	COG0406	alpha-ribazole phosphatase activity
BsBEST3136_10330	COG0183	Belongs to the thiolase family
BsBEST3136_10340	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3136_10350	COG1268	BioY protein
BsBEST3136_10360	COG0840	transmembrane signaling receptor activity
BsBEST3136_10370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3136_10370	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3136_10380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3136_10380	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3136_10390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3136_10390	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3136_10400	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_10420	COG4903	ComK protein
BsBEST3136_10430	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_10450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3136_10480	COG0398	Pfam SNARE associated Golgi protein
BsBEST3136_10490	COG0681	Belongs to the peptidase S26 family
BsBEST3136_10500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3136_10510	COG1846	Transcriptional regulator
BsBEST3136_10540	COG0738	Major facilitator superfamily
BsBEST3136_10570	COG0673	inositol 2-dehydrogenase activity
BsBEST3136_10580	COG0561	phosphatase activity
BsBEST3136_10590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3136_10600	COG1609	Transcriptional regulator
BsBEST3136_10610	COG3180	Ammonia monooxygenase
BsBEST3136_10620	COG0477	Major facilitator Superfamily
BsBEST3136_10620	COG2814	Major facilitator Superfamily
BsBEST3136_10630	COG4533	DNA binding
BsBEST3136_10650	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BsBEST3136_10660	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BsBEST3136_10670	COG1074	ATP-dependent DNA helicase activity
BsBEST3136_10680	COG0420	3'-5' exonuclease activity
BsBEST3136_10690	COG0419	ATPase involved in DNA repair
BsBEST3136_10700	COG1403	HNH endonuclease
BsBEST3136_10780	COG0179	Fumarylacetoacetate (FAA) hydrolase
BsBEST3136_10800	COG1404	Belongs to the peptidase S8 family
BsBEST3136_10820	COG0367	asparagine synthase
BsBEST3136_10830	COG1562	ergosterol biosynthetic process
BsBEST3136_10840	COG0534	Mate efflux family protein
BsBEST3136_10850	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3136_10850	COG2207	Transcriptional regulator
BsBEST3136_10860	COG1609	Transcriptional regulator
BsBEST3136_10870	COG0673	inositol 2-dehydrogenase activity
BsBEST3136_10880	COG2318	DinB family
BsBEST3136_10890	COG1279	arginine transmembrane transporter activity
BsBEST3136_10900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3136_10910	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3136_10920	COG2267	carboxylic ester hydrolase activity
BsBEST3136_10930	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3136_10940	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3136_10950	COG0175	sulfate reduction
BsBEST3136_10960	COG2045	Belongs to the ComB family
BsBEST3136_10970	COG1809	phosphosulfolactate synthase activity
BsBEST3136_10980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3136_10990	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3136_11000	COG2814	Major facilitator Superfamily
BsBEST3136_11010	COG0454	-acetyltransferase
BsBEST3136_11020	COG2153	protein acetylation
BsBEST3136_11030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BsBEST3136_11030	COG0646	methionine synthase
BsBEST3136_11040	COG1666	GTP binding
BsBEST3136_11050	COG2996	Protein conserved in bacteria
BsBEST3136_11090	COG1695	Transcriptional regulator
BsBEST3136_11120	COG3227	Zinc metalloprotease (Elastase)
BsBEST3136_11130	COG1307	EDD domain protein, DegV family
BsBEST3136_11140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3136_11180	COG0561	phosphatase activity
BsBEST3136_11190	COG1073	alpha beta
BsBEST3136_11200	COG2151	metal-sulfur cluster biosynthetic enzyme
BsBEST3136_11220	COG0277	FAD linked oxidase domain protein
BsBEST3136_11230	COG2271	Major facilitator Superfamily
BsBEST3136_11240	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BsBEST3136_11250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BsBEST3136_11270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3136_11280	COG0505	Belongs to the CarA family
BsBEST3136_11290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3136_11300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BsBEST3136_11330	COG2267	carboxylic ester hydrolase activity
BsBEST3136_11350	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3136_11380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3136_11390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3136_11400	COG5504	Zn-dependent protease
BsBEST3136_11410	COG0444	Belongs to the ABC transporter superfamily
BsBEST3136_11420	COG4608	Belongs to the ABC transporter superfamily
BsBEST3136_11450	COG0601	transmembrane transport
BsBEST3136_11460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3136_11480	COG0180	Tryptophanyl-tRNA synthetase
BsBEST3136_11490	COG4166	transmembrane transport
BsBEST3136_11500	COG0601	transmembrane transport
BsBEST3136_11510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3136_11520	COG0444	Belongs to the ABC transporter superfamily
BsBEST3136_11530	COG4608	Belongs to the ABC transporter superfamily
BsBEST3136_11540	COG2814	Major facilitator Superfamily
BsBEST3136_11550	COG0456	acetyltransferase
BsBEST3136_11560	COG1393	Belongs to the ArsC family
BsBEST3136_11570	COG0861	Integral membrane protein TerC family
BsBEST3136_11580	COG4862	establishment of competence for transformation
BsBEST3136_11590	COG1164	Oligoendopeptidase f
BsBEST3136_11610	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3136_11620	COG2346	COG2346, Truncated hemoglobins
BsBEST3136_11630	COG0741	lytic transglycosylase activity
BsBEST3136_11640	COG4116	CYTH
BsBEST3136_11660	COG2357	RelA SpoT domain protein
BsBEST3136_11670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3136_11680	COG0564	pseudouridine synthase activity
BsBEST3136_11690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BsBEST3136_11700	COG0475	glutathione-regulated potassium exporter activity
BsBEST3136_11700	COG0569	domain protein
BsBEST3136_11710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BsBEST3136_11720	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3136_11730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3136_11740	COG2104	thiamine diphosphate biosynthetic process
BsBEST3136_11750	COG2022	thiamine diphosphate biosynthetic process
BsBEST3136_11760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3136_11770	COG0351	phosphomethylpyrimidine kinase
BsBEST3136_11780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BsBEST3136_11890	COG0210	DNA helicase
BsBEST3136_11910	COG2153	protein acetylation
BsBEST3136_11920	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3136_11930	COG2382	esterase
BsBEST3136_11940	COG0626	cystathionine gamma-synthase activity
BsBEST3136_11950	COG0626	cystathionine gamma-synthase activity
BsBEST3136_11960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3136_11970	COG5505	Protein of unknown function (DUF819)
BsBEST3136_12030	COG3677	Transposase
BsBEST3136_12060	COG5484	DNA packaging
BsBEST3136_12070	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3136_12080	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_12100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3136_12100	COG3711	transcriptional antiterminator
BsBEST3136_12110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3136_12110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3136_12110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3136_12120	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3136_12140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3136_12160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3136_12200	COG0109	protoheme IX farnesyltransferase activity
BsBEST3136_12220	COG0726	polysaccharide deacetylase
BsBEST3136_12250	COG5504	Zn-dependent protease
BsBEST3136_12260	COG2205	protein histidine kinase activity
BsBEST3136_12280	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3136_12290	COG2427	Protein of unknown function (DUF1641)
BsBEST3136_12310	COG1051	belongs to the nudix hydrolase family
BsBEST3136_12330	COG2124	cytochrome p450
BsBEST3136_12340	COG1819	glycosyl
BsBEST3136_12360	COG1587	Uroporphyrinogen-III synthase
BsBEST3136_12370	COG0390	transport system, permease component
BsBEST3136_12380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3136_12390	COG0697	spore germination
BsBEST3136_12400	COG4297	protein containing double-stranded beta helix domain
BsBEST3136_12420	COG1252	NADH dehydrogenase
BsBEST3136_12430	COG1904	glucuronate isomerase
BsBEST3136_12440	COG2211	Major facilitator Superfamily
BsBEST3136_12450	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BsBEST3136_12460	COG1063	alcohol dehydrogenase
BsBEST3136_12470	COG1312	Catalyzes the dehydration of D-mannonate
BsBEST3136_12480	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_12490	COG2271	Major facilitator Superfamily
BsBEST3136_12500	COG1609	Transcriptional regulator
BsBEST3136_12510	COG0246	Mannitol dehydrogenase
BsBEST3136_12520	COG2721	sulfolactate sulfo-lyase activity
BsBEST3136_12530	COG0730	response to heat
BsBEST3136_12540	COG2318	DinB family
BsBEST3136_12550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3136_12560	COG0457	Tetratricopeptide repeat
BsBEST3136_12580	COG2350	Protein conserved in bacteria
BsBEST3136_12590	COG1388	LysM domain
BsBEST3136_12590	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_12590	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_12610	COG4195	phage-related replication protein
BsBEST3136_12620	COG3546	catalase activity
BsBEST3136_12630	COG2856	Zn peptidase
BsBEST3136_12640	COG1396	sequence-specific DNA binding
BsBEST3136_12660	COG1522	sequence-specific DNA binding
BsBEST3136_12670	COG1484	DNA-dependent DNA replication
BsBEST3136_12710	COG1595	DNA-templated transcription, initiation
BsBEST3136_12720	COG3728	DNA packaging
BsBEST3136_12720	COG5484	DNA packaging
BsBEST3136_12730	COG1783	phage Terminase large subunit
BsBEST3136_12740	COG5518	Phage portal protein
BsBEST3136_12750	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3136_12760	COG4653	Phage capsid family
BsBEST3136_12860	COG3953	SLT domain
BsBEST3136_12860	COG5412	phage tail tape measure protein
BsBEST3136_12870	COG1652	LysM domain
BsBEST3136_12880	COG4193	domain, Protein
BsBEST3136_12900	COG3628	GPW Gp25 family protein
BsBEST3136_12910	COG3299	homolog of phage Mu protein gp47
BsBEST3136_12920	COG3778	Protein conserved in bacteria
BsBEST3136_13000	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_13000	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_13030	COG0306	phosphate transporter
BsBEST3136_13040	COG1392	Phosphate transport regulator
BsBEST3136_13050	COG0531	amino acid
BsBEST3136_13060	COG0346	lactoylglutathione lyase activity
BsBEST3136_13080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3136_13090	COG0463	Glycosyl transferase, family 2
BsBEST3136_13110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3136_13120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3136_13130	COG2362	D-Aminopeptidase
BsBEST3136_13140	COG0601	transmembrane transport
BsBEST3136_13150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3136_13160	COG0444	Belongs to the ABC transporter superfamily
BsBEST3136_13170	COG4166	transmembrane transport
BsBEST3136_13180	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3136_13190	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3136_13200	COG0791	NLP P60 protein
BsBEST3136_13210	COG4608	Belongs to the ABC transporter superfamily
BsBEST3136_13220	COG2706	6-phosphogluconolactonase activity
BsBEST3136_13230	COG1834	amidinotransferase
BsBEST3136_13240	COG1607	acyl-coa hydrolase
BsBEST3136_13250	COG1017	nitric oxide dioxygenase activity
BsBEST3136_13250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BsBEST3136_13270	COG2323	membrane
BsBEST3136_13280	COG2318	DinB family
BsBEST3136_13290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3136_13300	COG2076	Multidrug Resistance protein
BsBEST3136_13310	COG2076	Multidrug Resistance protein
BsBEST3136_13320	COG0788	formyltetrahydrofolate deformylase activity
BsBEST3136_13330	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3136_13340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BsBEST3136_13350	COG1764	response to oxidative stress
BsBEST3136_13360	COG1846	Transcriptional regulator
BsBEST3136_13370	COG1764	response to oxidative stress
BsBEST3136_13390	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3136_13400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3136_13410	COG1404	Belongs to the peptidase S8 family
BsBEST3136_13420	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3136_13430	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3136_13440	COG1122	ATPase activity
BsBEST3136_13450	COG4721	ABC-type cobalt transport system, permease component
BsBEST3136_13470	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_13480	COG5002	protein histidine kinase activity
BsBEST3136_13480	COG3850	Histidine kinase
BsBEST3136_13490	COG3212	peptidase
BsBEST3136_13500	COG3212	peptidase
BsBEST3136_13530	COG2239	Acts as a magnesium transporter
BsBEST3136_13540	COG0789	Transcriptional regulator
BsBEST3136_13570	COG1846	Transcriptional regulator
BsBEST3136_13580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3136_13590	COG0726	polysaccharide deacetylase
BsBEST3136_13600	COG1408	metallophosphoesterase
BsBEST3136_13620	COG0463	Glycosyl transferase, family 2
BsBEST3136_13630	COG1793	dna ligase
BsBEST3136_13630	COG3285	dna ligase
BsBEST3136_13640	COG3285	dna ligase
BsBEST3136_13640	COG1793	dna ligase
BsBEST3136_13650	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BsBEST3136_13660	COG3300	MHYT domain
BsBEST3136_13660	COG5001	Diguanylate cyclase
BsBEST3136_13670	COG0586	Pfam SNARE associated Golgi protein
BsBEST3136_13680	COG0861	Integral membrane protein TerC family
BsBEST3136_13690	COG1191	sigma factor activity
BsBEST3136_13730	COG0501	Belongs to the peptidase M48B family
BsBEST3136_13740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3136_13770	COG3594	Acyltransferase
BsBEST3136_13780	COG5002	protein histidine kinase activity
BsBEST3136_13790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3136_13810	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BsBEST3136_13820	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BsBEST3136_13830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3136_13840	COG0436	Aminotransferase
BsBEST3136_13850	COG1850	ribulose-bisphosphate carboxylase activity
BsBEST3136_13860	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BsBEST3136_13870	COG0235	Class ii aldolase
BsBEST3136_13880	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BsBEST3136_13890	COG3339	Conserved Protein
BsBEST3136_13920	COG3852	Histidine kinase
BsBEST3136_13930	COG1846	Transcriptional regulator
BsBEST3136_13940	COG1360	Flagellar Motor Protein
BsBEST3136_13950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3136_13960	COG0542	response to heat
BsBEST3136_13970	COG3949	Membrane
BsBEST3136_13980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BsBEST3136_13990	COG0720	synthase
BsBEST3136_14000	COG0602	queuosine metabolic process
BsBEST3136_14010	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BsBEST3136_14020	COG1733	regulation of RNA biosynthetic process
BsBEST3136_14030	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_14040	COG1388	LysM domain
BsBEST3136_14040	COG4641	Protein conserved in bacteria
BsBEST3136_14050	COG1388	LysM domain
BsBEST3136_14060	COG3858	chitin binding
BsBEST3136_14070	COG3858	chitin binding
BsBEST3136_14090	COG4873	Protein conserved in bacteria
BsBEST3136_14110	COG3773	Cell wall hydrolase
BsBEST3136_14120	COG2244	polysaccharide biosynthetic process
BsBEST3136_14130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_14140	COG2217	Heavy metal translocating P-type atpase
BsBEST3136_14160	COG0006	proline dipeptidase activity
BsBEST3136_14180	COG1609	Transcriptional regulator
BsBEST3136_14190	COG3711	transcriptional antiterminator
BsBEST3136_14200	COG1263	PTS System
BsBEST3136_14200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3136_14200	COG2190	(PTS) system
BsBEST3136_14210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3136_14220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BsBEST3136_14240	COG1533	DNA photolyase activity
BsBEST3136_14250	COG0456	acetyltransferase
BsBEST3136_14260	COG0840	transmembrane signaling receptor activity
BsBEST3136_14270	COG2084	Dehydrogenase
BsBEST3136_14280	COG2340	Cysteine-rich secretory protein family
BsBEST3136_14290	COG0768	penicillin binding
BsBEST3136_14300	COG4191	Histidine kinase
BsBEST3136_14310	COG0436	Aminotransferase
BsBEST3136_14330	COG0784	Response regulator, receiver
BsBEST3136_14330	COG0835	chemotaxis
BsBEST3136_14350	COG2814	Major facilitator Superfamily
BsBEST3136_14360	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3136_14370	COG1408	metallophosphoesterase
BsBEST3136_14380	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_14390	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_14400	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_14420	COG2200	EAL domain
BsBEST3136_14430	COG4703	Protein of unknown function (DUF1797)
BsBEST3136_14440	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BsBEST3136_14460	COG0517	IMP dehydrogenase activity
BsBEST3136_14470	COG0583	DNA-binding transcription factor activity
BsBEST3136_14480	COG0716	FMN binding
BsBEST3136_14500	COG0716	FMN binding
BsBEST3136_14510	COG2171	N-acyltransferase activity
BsBEST3136_14520	COG1473	amidohydrolase
BsBEST3136_14540	COG0668	transmembrane transport
BsBEST3136_14550	COG0450	alkyl hydroperoxide reductase
BsBEST3136_14560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_14590	COG0746	molybdenum cofactor guanylyltransferase activity
BsBEST3136_14600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3136_14610	COG0303	'Molybdopterin
BsBEST3136_14620	COG1763	Mo-molybdopterin cofactor biosynthetic process
BsBEST3136_14630	COG0314	molybdopterin synthase activity
BsBEST3136_14640	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BsBEST3136_14650	COG1132	(ABC) transporter
BsBEST3136_14660	COG1132	(ABC) transporter
BsBEST3136_14680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3136_14690	COG1136	(ABC) transporter
BsBEST3136_14700	COG0577	efflux transmembrane transporter activity
BsBEST3136_14710	COG1349	DNA-binding transcription factor activity
BsBEST3136_14720	COG1105	Belongs to the carbohydrate kinase PfkB family
BsBEST3136_14730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3136_14730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3136_14730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3136_14740	COG0681	Belongs to the peptidase S26 family
BsBEST3136_14760	COG0488	(ABC) transporter
BsBEST3136_14770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3136_14780	COG2309	aminopeptidase activity
BsBEST3136_14800	COG1077	Cell shape determining protein MreB Mrl
BsBEST3136_14810	COG2002	toxin-antitoxin pair type II binding
BsBEST3136_14820	COG3852	Histidine kinase
BsBEST3136_14830	COG2105	PFAM AIG2 family protein
BsBEST3136_14830	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BsBEST3136_14840	COG0569	domain protein
BsBEST3136_14850	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3136_14860	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3136_14870	COG5503	Protein of unknown function (DUF1447)
BsBEST3136_14880	COG0561	phosphatase activity
BsBEST3136_14890	COG0242	peptide deformylase activity
BsBEST3136_14910	COG0497	DNA recombination
BsBEST3136_14920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3136_14930	COG0022	dehydrogenase e1 component
BsBEST3136_14940	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3136_14950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3136_14960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_14970	COG1982	Orn Lys Arg decarboxylase major
BsBEST3136_14980	COG4476	Belongs to the UPF0223 family
BsBEST3136_14990	COG4493	Belongs to the UPF0637 family
BsBEST3136_15010	COG0483	inositol monophosphate 1-phosphatase activity
BsBEST3136_15030	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BsBEST3136_15070	COG1595	DNA-templated transcription, initiation
BsBEST3136_15110	COG1217	gtp-binding protein TYPA
BsBEST3136_15130	COG4896	Protein conserved in bacteria
BsBEST3136_15150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BsBEST3136_15160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3136_15170	COG2066	Belongs to the glutaminase family
BsBEST3136_15180	COG4838	Belongs to the UPF0358 family
BsBEST3136_15200	COG0772	Belongs to the SEDS family
BsBEST3136_15210	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BsBEST3136_15220	COG1612	heme a metabolic process
BsBEST3136_15230	COG0109	protoheme IX farnesyltransferase activity
BsBEST3136_15240	COG2010	Cytochrome c
BsBEST3136_15240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3136_15250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3136_15260	COG1845	cytochrome c oxidase, subunit III
BsBEST3136_15270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3136_15280	COG3336	cytochrome c oxidase
BsBEST3136_15300	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BsBEST3136_15310	COG2340	Cysteine-rich secretory protein family
BsBEST3136_15340	COG3679	Belongs to the UPF0342 family
BsBEST3136_15350	COG4471	UPF0298 protein
BsBEST3136_15360	COG0742	ribosomal rna small subunit methyltransferase
BsBEST3136_15370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BsBEST3136_15380	COG3314	Sporulation integral membrane protein YlbJ
BsBEST3136_15390	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3136_15400	COG3480	Lon protease (S16) C-terminal proteolytic domain
BsBEST3136_15410	COG1323	Belongs to the UPF0348 family
BsBEST3136_15420	COG1399	metal-binding, possibly nucleic acid-binding protein
BsBEST3136_15450	COG0454	-acetyltransferase
BsBEST3136_15460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3136_15470	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BsBEST3136_15480	COG2001	Belongs to the MraZ family
BsBEST3136_15490	COG0275	rRNA processing
BsBEST3136_15500	COG4839	cell division protein FtsL
BsBEST3136_15510	COG0768	penicillin binding
BsBEST3136_15520	COG0768	penicillin binding
BsBEST3136_15530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BsBEST3136_15540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3136_15550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3136_15560	COG0772	Belongs to the SEDS family
BsBEST3136_15570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3136_15580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BsBEST3136_15590	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BsBEST3136_15600	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3136_15610	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3136_15620	COG3856	small basic protein
BsBEST3136_15630	COG0849	cell division
BsBEST3136_15640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BsBEST3136_15650	COG1404	Belongs to the peptidase S8 family
BsBEST3136_15650	COG4412	M6 family metalloprotease domain protein
BsBEST3136_15670	COG1191	sigma factor activity
BsBEST3136_15680	COG1191	sigma factor activity
BsBEST3136_15690	COG1119	ATPase activity
BsBEST3136_15700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3136_15710	COG1873	PFAM PRC-barrel domain
BsBEST3136_15720	COG1496	oxidoreductase activity
BsBEST3136_15730	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BsBEST3136_15740	COG1799	cell septum assembly
BsBEST3136_15750	COG0762	integral membrane protein
BsBEST3136_15760	COG2302	S4 RNA-binding domain
BsBEST3136_15770	COG3599	regulation of cell shape
BsBEST3136_15780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BsBEST3136_15790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3136_15800	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BsBEST3136_15810	COG0564	pseudouridine synthase activity
BsBEST3136_15820	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BsBEST3136_15830	COG2233	PERMEase
BsBEST3136_15840	COG0540	Belongs to the ATCase OTCase family
BsBEST3136_15850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3136_15860	COG0505	Belongs to the CarA family
BsBEST3136_15870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3136_15880	COG0543	2 iron, 2 sulfur cluster binding
BsBEST3136_15890	COG0167	dihydroorotate dehydrogenase activity
BsBEST3136_15900	COG0284	orotidine-5'-phosphate decarboxylase activity
BsBEST3136_15910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BsBEST3136_15920	COG0175	sulfate reduction
BsBEST3136_15930	COG0306	phosphate transporter
BsBEST3136_15940	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3136_15950	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3136_15960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3136_15970	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BsBEST3136_15980	COG1648	precorrin-2 dehydrogenase activity
BsBEST3136_15990	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BsBEST3136_16000	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3136_16010	COG1561	YicC-like family, N-terminal region
BsBEST3136_16030	COG0194	GDP metabolic process
BsBEST3136_16040	COG1758	RNA polymerase activity
BsBEST3136_16050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3136_16060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3136_16070	COG0242	peptide deformylase activity
BsBEST3136_16080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BsBEST3136_16090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3136_16090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BsBEST3136_16100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BsBEST3136_16110	COG0631	protein serine/threonine phosphatase activity
BsBEST3136_16120	COG0515	serine threonine protein kinase
BsBEST3136_16120	COG2815	serine threonine protein kinase
BsBEST3136_16130	COG1162	GTPase activity
BsBEST3136_16140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BsBEST3136_16150	COG1564	THIamine pyrophosphokinase
BsBEST3136_16160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BsBEST3136_16170	COG1302	Protein conserved in bacteria
BsBEST3136_16180	COG1461	Dihydroxyacetone kinase
BsBEST3136_16190	COG1760	l-serine dehydratase
BsBEST3136_16200	COG1760	l-serine dehydratase
BsBEST3136_16210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BsBEST3136_16220	COG1349	DNA-binding transcription factor activity
BsBEST3136_16220	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3136_16230	COG0416	fatty acid biosynthetic process
BsBEST3136_16240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3136_16250	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_16270	COG0571	ribonuclease III activity
BsBEST3136_16280	COG1196	nuclear chromosome segregation
BsBEST3136_16290	COG0552	protein localization to endoplasmic reticulum
BsBEST3136_16310	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BsBEST3136_16320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BsBEST3136_16330	COG0228	four-way junction DNA binding
BsBEST3136_16340	COG1837	Belongs to the UPF0109 family
BsBEST3136_16360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BsBEST3136_16370	COG0336	Belongs to the RNA methyltransferase TrmD family
BsBEST3136_16380	COG0335	large ribosomal subunit rRNA binding
BsBEST3136_16390	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3136_16400	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3136_16420	COG2257	FlhB HrpN YscU SpaS Family
BsBEST3136_16430	COG0045	succinate-CoA ligase (ADP-forming) activity
BsBEST3136_16440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BsBEST3136_16450	COG0758	DNA mediated transformation
BsBEST3136_16460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3136_16470	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BsBEST3136_16480	COG4974	Belongs to the 'phage' integrase family
BsBEST3136_16490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BsBEST3136_16500	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BsBEST3136_16510	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3136_16520	COG1815	bacterial-type flagellum-dependent cell motility
BsBEST3136_16530	COG1558	bacterial-type flagellum-dependent cell motility
BsBEST3136_16540	COG1677	Flagellar hook-basal body complex protein FliE
BsBEST3136_16550	COG1766	The M ring may be actively involved in energy transduction
BsBEST3136_16560	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3136_16570	COG1317	bacterial-type flagellum organization
BsBEST3136_16580	COG1157	protein secretion by the type III secretion system
BsBEST3136_16590	COG2882	bacterial-type flagellum organization
BsBEST3136_16600	COG3334	PFAM MgtE intracellular
BsBEST3136_16610	COG3144	bacterial-type flagellum assembly
BsBEST3136_16620	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BsBEST3136_16630	COG4786	Flagellar basal body rod
BsBEST3136_16640	COG1582	Flagellar protein (FlbD)
BsBEST3136_16650	COG1580	Controls the rotational direction of flagella during chemotaxis
BsBEST3136_16660	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3136_16670	COG1776	CheC inhibitor of MCP methylation
BsBEST3136_16670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3136_16680	COG2201	protein-glutamate methylesterase activity
BsBEST3136_16690	COG3190	flagellar
BsBEST3136_16700	COG1338	Plays a role in the flagellum-specific transport system
BsBEST3136_16710	COG1987	bacterial-type flagellum assembly
BsBEST3136_16720	COG1684	flagellar biosynthetic protein fliR
BsBEST3136_16730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3136_16740	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3136_16750	COG1419	protein localization to endoplasmic reticulum
BsBEST3136_16760	COG0455	bacterial-type flagellum organization
BsBEST3136_16770	COG2201	protein-glutamate methylesterase activity
BsBEST3136_16780	COG0643	Histidine kinase
BsBEST3136_16780	COG2198	Histidine kinase
BsBEST3136_16790	COG0835	chemotaxis
BsBEST3136_16800	COG1776	CheC inhibitor of MCP methylation
BsBEST3136_16810	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BsBEST3136_16820	COG1191	sigma factor activity
BsBEST3136_16840	COG0052	Belongs to the universal ribosomal protein uS2 family
BsBEST3136_16850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BsBEST3136_16860	COG0528	UMP kinase activity
BsBEST3136_16870	COG0233	cytoplasmic translational termination
BsBEST3136_16880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BsBEST3136_16890	COG4589	Belongs to the CDS family
BsBEST3136_16900	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BsBEST3136_16910	COG0750	zinc metalloprotease
BsBEST3136_16920	COG0442	prolyl-tRNA aminoacylation
BsBEST3136_16930	COG2176	DNA-directed DNA polymerase activity
BsBEST3136_16940	COG0779	Required for maturation of 30S ribosomal subunits
BsBEST3136_16950	COG0195	Participates in both transcription termination and antitermination
BsBEST3136_16960	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BsBEST3136_16970	COG1358	cellular component organization or biogenesis
BsBEST3136_16980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BsBEST3136_16990	COG1550	Protein conserved in bacteria
BsBEST3136_17000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BsBEST3136_17010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BsBEST3136_17020	COG0196	riboflavin kinase activity
BsBEST3136_17030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BsBEST3136_17040	COG1185	polyribonucleotide nucleotidyltransferase activity
BsBEST3136_17050	COG0726	polysaccharide deacetylase
BsBEST3136_17060	COG0612	Peptidase, M16
BsBEST3136_17070	COG1873	PFAM PRC-barrel domain
BsBEST3136_17080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3136_17090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3136_17100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BsBEST3136_17110	COG0527	aspartate kinase activity
BsBEST3136_17120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3136_17130	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3136_17140	COG0740	serine-type endopeptidase activity
BsBEST3136_17160	COG1674	ftsk spoiiie
BsBEST3136_17160	COG4980	gas vesicle protein
BsBEST3136_17170	COG2188	Transcriptional regulator
BsBEST3136_17180	COG2814	Major facilitator Superfamily
BsBEST3136_17190	COG0612	Peptidase, M16
BsBEST3136_17200	COG0612	Peptidase, M16
BsBEST3136_17210	COG0300	oxidoreductase activity
BsBEST3136_17250	COG1426	Protein conserved in bacteria
BsBEST3136_17260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BsBEST3136_17270	COG1058	Belongs to the CinA family
BsBEST3136_17270	COG1546	Belongs to the CinA family
BsBEST3136_17280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BsBEST3136_17290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3136_17300	COG1418	mRNA catabolic process
BsBEST3136_17310	COG1692	metallophosphoesterase
BsBEST3136_17320	COG2359	stage V sporulation protein S
BsBEST3136_17330	COG1063	alcohol dehydrogenase
BsBEST3136_17340	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3136_17350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3136_17360	COG4550	Control of competence regulator ComK, YlbF/YmcA
BsBEST3136_17380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BsBEST3136_17390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BsBEST3136_17420	COG3226	Transcriptional regulator
BsBEST3136_17430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3136_17450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3136_17460	COG3321	synthase
BsBEST3136_17470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3136_17470	COG2070	2-Nitropropane dioxygenase
BsBEST3136_17480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3136_17490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3136_17500	COG3425	synthase
BsBEST3136_17510	COG1024	Enoyl-CoA hydratase
BsBEST3136_17520	COG1024	Enoyl-CoA hydratase
BsBEST3136_17530	COG0300	oxidoreductase activity
BsBEST3136_17530	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3136_17530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_17530	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_17530	COG3321	synthase
BsBEST3136_17540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3136_17540	COG0300	oxidoreductase activity
BsBEST3136_17540	COG3321	synthase
BsBEST3136_17540	COG4221	oxidoreductase activity
BsBEST3136_17550	COG3321	synthase
BsBEST3136_17550	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_17550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3136_17550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3136_17550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_17560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_17560	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_17560	COG3321	synthase
BsBEST3136_17560	COG4221	oxidoreductase activity
BsBEST3136_17570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_17570	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_17570	COG3321	synthase
BsBEST3136_17570	COG4221	oxidoreductase activity
BsBEST3136_17580	COG3321	synthase
BsBEST3136_17580	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3136_17580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BsBEST3136_17580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3136_17590	COG2124	cytochrome p450
BsBEST3136_17610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3136_17620	COG1404	Belongs to the peptidase S8 family
BsBEST3136_17630	COG4195	phage-related replication protein
BsBEST3136_17640	COG1764	response to oxidative stress
BsBEST3136_17650	COG2076	Multidrug Resistance protein
BsBEST3136_17660	COG2076	Multidrug Resistance protein
BsBEST3136_17690	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BsBEST3136_17700	COG1923	regulation of RNA biosynthetic process
BsBEST3136_17730	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3136_17740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3136_17750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3136_17760	COG4112	unkown
BsBEST3136_17770	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_17780	COG0464	growth
BsBEST3136_17790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BsBEST3136_17800	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BsBEST3136_17810	COG0789	Transcriptional regulator
BsBEST3136_17820	COG0174	glutamine synthetase
BsBEST3136_17860	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3136_17880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3136_17930	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3136_17940	COG2211	Major facilitator Superfamily
BsBEST3136_17950	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3136_17960	COG1940	carbohydrate kinase activity
BsBEST3136_17970	COG2115	Belongs to the xylose isomerase family
BsBEST3136_17980	COG1070	Carbohydrate kinase
BsBEST3136_17990	COG1525	nuclease
BsBEST3136_18000	COG2814	Major facilitator Superfamily
BsBEST3136_18010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3136_18030	COG0756	dUTP diphosphatase activity
BsBEST3136_18080	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3136_18130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3136_18150	COG3832	glyoxalase III activity
BsBEST3136_18170	COG0697	spore germination
BsBEST3136_18180	COG0531	amino acid
BsBEST3136_18240	COG4195	phage-related replication protein
BsBEST3136_18260	COG0346	lactoylglutathione lyase activity
BsBEST3136_18270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BsBEST3136_18280	COG1388	LysM domain
BsBEST3136_18290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3136_18300	COG4224	UPF0291 protein
BsBEST3136_18310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BsBEST3136_18330	COG3763	UPF0154 protein
BsBEST3136_18350	COG0785	Cytochrome C biogenesis protein
BsBEST3136_18360	COG2201	protein-glutamate methylesterase activity
BsBEST3136_18370	COG4846	Membrane protein involved in cytochrome C biogenesis
BsBEST3136_18390	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3136_18420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BsBEST3136_18430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_18470	COG0824	Thioesterase
BsBEST3136_18490	COG4841	protein insertion into membrane
BsBEST3136_18500	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BsBEST3136_18510	COG1832	CoA-binding protein
BsBEST3136_18520	COG0187	DNA topoisomerase II activity
BsBEST3136_18530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3136_18550	COG1115	amino acid carrier protein
BsBEST3136_18560	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BsBEST3136_18580	COG5520	Belongs to the glycosyl hydrolase 30 family
BsBEST3136_18590	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3136_18600	COG2246	polysaccharide biosynthetic process
BsBEST3136_18610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3136_18620	COG0586	Pfam SNARE associated Golgi protein
BsBEST3136_18630	COG2404	hydrolase activity, acting on ester bonds
BsBEST3136_18640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3136_18650	COG1024	Enoyl-CoA hydratase
BsBEST3136_18660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3136_18670	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3136_18680	COG0439	Biotin carboxylase
BsBEST3136_18690	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3136_18700	COG1960	acyl-CoA dehydrogenase activity
BsBEST3136_18720	COG1649	PFAM Uncharacterised BCR, COG1649
BsBEST3136_18740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_18740	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3136_18750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_18760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_18770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_18780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_18790	COG2027	D-alanyl-D-alanine carboxypeptidase
BsBEST3136_18800	COG2017	converts alpha-aldose to the beta-anomer
BsBEST3136_18810	COG0534	Mate efflux family protein
BsBEST3136_18830	COG0582	viral genome integration into host DNA
BsBEST3136_18840	COG0166	Belongs to the GPI family
BsBEST3136_18850	COG0405	Gamma-glutamyltransferase
BsBEST3136_18860	COG0583	DNA-binding transcription factor activity
BsBEST3136_18870	COG0604	alcohol dehydrogenase
BsBEST3136_18880	COG0493	'glutamate synthase
BsBEST3136_18890	COG0067	glutamate synthase
BsBEST3136_18890	COG0069	glutamate synthase activity
BsBEST3136_18890	COG0070	glutamate synthase
BsBEST3136_18900	COG0583	DNA-binding transcription factor activity
BsBEST3136_18910	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3136_18920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3136_18940	COG0300	oxidoreductase activity
BsBEST3136_18950	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3136_18970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3136_18980	COG2814	Major facilitator Superfamily
BsBEST3136_18990	COG1070	Carbohydrate kinase
BsBEST3136_19000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3136_19010	COG0243	molybdopterin cofactor binding
BsBEST3136_19060	COG0840	transmembrane signaling receptor activity
BsBEST3136_19060	COG5278	phosphoserine phosphatase activity
BsBEST3136_19070	COG2368	4-hydroxyphenylacetate
BsBEST3136_19080	COG4305	rare lipoprotein A
BsBEST3136_19090	COG3619	membrane
BsBEST3136_19100	COG3866	Pectate lyase
BsBEST3136_19110	COG2135	peptidase activity
BsBEST3136_19130	COG2140	Oxalate decarboxylase
BsBEST3136_19150	COG0456	acetyltransferase
BsBEST3136_19180	COG2720	vancomycin resistance protein
BsBEST3136_19200	COG3655	Transcriptional regulator
BsBEST3136_19210	COG3739	integral membrane protein
BsBEST3136_19220	COG0583	DNA-binding transcription factor activity
BsBEST3136_19230	COG0697	spore germination
BsBEST3136_19250	COG0693	protein deglycase activity
BsBEST3136_19260	COG2367	Beta-lactamase
BsBEST3136_19300	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3136_19300	COG3848	Pyruvate phosphate dikinase
BsBEST3136_19310	COG0726	polysaccharide deacetylase
BsBEST3136_19320	COG2314	TM2 domain
BsBEST3136_19330	COG1396	sequence-specific DNA binding
BsBEST3136_19360	COG2135	peptidase activity
BsBEST3136_19420	COG0457	Tetratricopeptide repeat
BsBEST3136_19440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3136_19450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3136_19480	COG5290	Psort location Cytoplasmic, score
BsBEST3136_19530	COG5444	nuclease activity
BsBEST3136_19540	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3136_19550	COG1231	oxidoreductase activity
BsBEST3136_19560	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3136_19570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3136_19580	COG2207	Transcriptional regulator
BsBEST3136_19580	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3136_19590	COG0456	acetyltransferase
BsBEST3136_19600	COG1309	transcriptional regulator
BsBEST3136_19610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3136_19620	COG3708	Transcriptional regulator
BsBEST3136_19630	COG2378	regulation of single-species biofilm formation
BsBEST3136_19650	COG0640	Transcriptional regulator
BsBEST3136_19660	COG0741	lytic transglycosylase activity
BsBEST3136_19670	COG2322	membrane
BsBEST3136_19700	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3136_19710	COG3239	Fatty acid desaturase
BsBEST3136_19720	COG4585	Histidine kinase
BsBEST3136_19730	COG2197	response regulator
BsBEST3136_19740	COG3584	3D domain protein
BsBEST3136_19740	COG1388	LysM domain
BsBEST3136_19750	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3136_19760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3136_19770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3136_19800	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3136_19850	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_19860	COG1657	PFAM Prenyltransferase squalene oxidase
BsBEST3136_19870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3136_19880	COG0733	neurotransmitter:sodium symporter activity
BsBEST3136_19890	COG0385	Bile acid
BsBEST3136_19900	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3136_19910	COG0567	Dehydrogenase, E1 component
BsBEST3136_19920	COG4548	von Willebrand factor, type A
BsBEST3136_19930	COG0714	Associated with various cellular activities
BsBEST3136_19940	COG2032	superoxide dismutase activity
BsBEST3136_19950	COG0791	NLP P60 protein
BsBEST3136_19950	COG1388	LysM domain
BsBEST3136_19960	COG1819	glycosyl
BsBEST3136_19970	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3136_19980	COG0534	Mate efflux family protein
BsBEST3136_19990	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3136_20000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3136_20010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3136_20030	COG2962	Rard protein
BsBEST3136_20060	COG2610	gluconate transmembrane transporter activity
BsBEST3136_20070	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3136_20080	COG1733	regulation of RNA biosynthetic process
BsBEST3136_20090	COG0778	Nitroreductase
BsBEST3136_20100	COG0400	carboxylic ester hydrolase activity
BsBEST3136_20110	COG0346	lactoylglutathione lyase activity
BsBEST3136_20130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3136_20140	COG0793	Belongs to the peptidase S41A family
BsBEST3136_20140	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_20150	COG2226	methyltransferase
BsBEST3136_20170	COG1876	peptidase activity
BsBEST3136_20180	COG0813	purine-nucleoside phosphorylase activity
BsBEST3136_20210	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3136_20250	COG4479	Belongs to the UPF0346 family
BsBEST3136_20270	COG1509	lysine 2,3-aminomutase activity
BsBEST3136_20280	COG0456	acetyltransferase
BsBEST3136_20290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3136_20300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3136_20310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3136_20320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3136_20350	COG0456	acetyltransferase
BsBEST3136_20360	COG0463	Glycosyl transferase, family 2
BsBEST3136_20390	COG4641	Protein conserved in bacteria
BsBEST3136_20400	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BsBEST3136_20410	COG1086	Polysaccharide biosynthesis protein
BsBEST3136_20430	COG3331	DNA recombination
BsBEST3136_20520	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3136_20580	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BsBEST3136_20590	COG0756	dUTP diphosphatase activity
BsBEST3136_20600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_20610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3136_20630	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3136_20650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3136_20650	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3136_20660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3136_20660	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3136_20670	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3136_20850	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3136_20870	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BsBEST3136_20880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3136_20930	COG3584	3D domain protein
BsBEST3136_20940	COG0587	DNA-directed DNA polymerase activity
BsBEST3136_20950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3136_20960	COG0358	DNA primase activity
BsBEST3136_20970	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3136_20990	COG2887	Belongs to the helicase family. UvrD subfamily
BsBEST3136_21050	COG3420	alginic acid biosynthetic process
BsBEST3136_21050	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3136_21060	COG4195	phage-related replication protein
BsBEST3136_21090	COG2135	peptidase activity
BsBEST3136_21100	COG1793	dna ligase
BsBEST3136_21200	COG4474	Belongs to the UPF0398 family
BsBEST3136_21220	COG1388	LysM domain
BsBEST3136_21260	COG3646	Phage regulatory protein
BsBEST3136_21260	COG3645	SOS response
BsBEST3136_21370	COG3655	Transcriptional regulator
BsBEST3136_21400	COG0582	viral genome integration into host DNA
BsBEST3136_21560	COG3655	Transcriptional regulator
BsBEST3136_21630	COG1395	domain, Protein
BsBEST3136_21670	COG0776	regulation of translation
BsBEST3136_21730	COG4373	Mu-like prophage FluMu protein gp28
BsBEST3136_21930	COG0582	viral genome integration into host DNA
BsBEST3136_21990	COG0739	heme binding
BsBEST3136_21990	COG1196	nuclear chromosome segregation
BsBEST3136_21990	COG0741	lytic transglycosylase activity
BsBEST3136_22010	COG2433	Pfam Transposase IS66
BsBEST3136_22030	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3136_22030	COG4632	Exopolysaccharide biosynthesis protein
BsBEST3136_22060	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_22090	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3136_22100	COG0463	Glycosyl transferase, family 2
BsBEST3136_22110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_22120	COG2274	protein secretion by the type I secretion system
BsBEST3136_22120	COG3271	cysteine-type peptidase activity
BsBEST3136_22150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3136_22200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3136_22230	COG5444	nuclease activity
BsBEST3136_22240	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3136_22260	COG1525	nuclease
BsBEST3136_22280	COG2746	aminoglycoside 3-N-acetyltransferase activity
BsBEST3136_22330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3136_22340	COG1086	Polysaccharide biosynthesis protein
BsBEST3136_22350	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3136_22360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3136_22370	COG1846	Transcriptional regulator
BsBEST3136_22380	COG0534	Mate efflux family protein
BsBEST3136_22400	COG4698	Protein conserved in bacteria
BsBEST3136_22410	COG2755	lipolytic protein G-D-S-L family
BsBEST3136_22420	COG1999	signal sequence binding
BsBEST3136_22440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BsBEST3136_22450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3136_22460	COG1272	protein, Hemolysin III
BsBEST3136_22470	COG0204	Acyl-transferase
BsBEST3136_22480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3136_22490	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3136_22500	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3136_22520	COG2136	Putative SAM-dependent methyltransferase
BsBEST3136_22520	COG2521	methyltransferase
BsBEST3136_22540	COG0129	dihydroxy-acid dehydratase activity
BsBEST3136_22550	COG1413	lyase activity
BsBEST3136_22560	COG1418	mRNA catabolic process
BsBEST3136_22570	COG0386	Belongs to the glutathione peroxidase family
BsBEST3136_22580	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BsBEST3136_22590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3136_22600	COG1278	Cold shock
BsBEST3136_22640	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3136_22650	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BsBEST3136_22660	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3136_22680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3136_22710	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3136_22720	COG1755	Isoprenylcysteine carboxyl methyltransferase
BsBEST3136_22730	COG3424	synthase
BsBEST3136_22740	COG2233	PERMEase
BsBEST3136_22750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3136_22760	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BsBEST3136_22780	COG0800	Aldolase
BsBEST3136_22790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3136_22800	COG1609	Transcriptional regulator
BsBEST3136_22810	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BsBEST3136_22820	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_22830	COG1199	ATP-dependent helicase activity
BsBEST3136_22850	COG0116	Belongs to the methyltransferase superfamily
BsBEST3136_22870	COG4474	Belongs to the UPF0398 family
BsBEST3136_22880	COG3359	exonuclease
BsBEST3136_22890	COG1111	helicase
BsBEST3136_22890	COG1205	dead DEAH box helicase
BsBEST3136_22900	COG2190	(PTS) system
BsBEST3136_22910	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3136_22970	COG3331	DNA recombination
BsBEST3136_22980	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3136_22980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3136_23000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BsBEST3136_23010	COG3935	DnaD domain protein
BsBEST3136_23020	COG0017	Asparaginyl-tRNA synthetase
BsBEST3136_23030	COG0436	Aminotransferase
BsBEST3136_23040	COG5353	protein conserved in bacteria
BsBEST3136_23060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BsBEST3136_23060	COG1199	ATP-dependent helicase activity
BsBEST3136_23070	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BsBEST3136_23080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BsBEST3136_23090	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BsBEST3136_23100	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BsBEST3136_23100	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BsBEST3136_23110	COG0617	tRNA 3'-terminal CCA addition
BsBEST3136_23120	COG0438	transferase activity, transferring glycosyl groups
BsBEST3136_23130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3136_23140	COG1803	Methylglyoxal synthase
BsBEST3136_23150	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BsBEST3136_23160	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3136_23170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3136_23190	COG4347	Protein of unknown function (DUF1405)
BsBEST3136_23200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3136_23200	COG2010	Cytochrome c
BsBEST3136_23210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3136_23220	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3136_23240	COG5582	Belongs to the UPF0302 family
BsBEST3136_23250	COG0457	Tetratricopeptide repeat
BsBEST3136_23260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BsBEST3136_23270	COG0287	Prephenate dehydrogenase
BsBEST3136_23280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BsBEST3136_23290	COG0159	tryptophan synthase activity
BsBEST3136_23300	COG0133	tryptophan synthase activity
BsBEST3136_23310	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3136_23330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BsBEST3136_23340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3136_23350	COG4401	Chorismate mutase type I
BsBEST3136_23360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BsBEST3136_23370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BsBEST3136_23380	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BsBEST3136_23390	COG0105	UTP biosynthetic process
BsBEST3136_23400	COG0142	geranyltranstransferase activity
BsBEST3136_23410	COG2226	methyltransferase
BsBEST3136_23420	COG0142	geranyltranstransferase activity
BsBEST3136_23440	COG0302	gtp cyclohydrolase
BsBEST3136_23450	COG0776	regulation of translation
BsBEST3136_23460	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3136_23490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BsBEST3136_23500	COG1160	GTP binding
BsBEST3136_23550	COG1304	FMN binding
BsBEST3136_23560	COG0539	negative regulation of cytoplasmic translation
BsBEST3136_23570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BsBEST3136_23590	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BsBEST3136_23600	COG2959	enzyme of heme biosynthesis
BsBEST3136_23610	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_23610	COG3773	Cell wall hydrolase
BsBEST3136_23620	COG2339	peptidase activity
BsBEST3136_23630	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3136_23640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3136_23650	COG4862	establishment of competence for transformation
BsBEST3136_23660	COG1408	metallophosphoesterase
BsBEST3136_23670	COG1388	LysM domain
BsBEST3136_23680	COG1266	CAAX protease self-immunity
BsBEST3136_23690	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3136_23700	COG4955	Helix-turn-helix domain
BsBEST3136_23710	COG1141	Ferredoxin
BsBEST3136_23720	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BsBEST3136_23740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3136_23750	COG0710	3-dehydroquinate dehydratase activity
BsBEST3136_23770	COG1595	DNA-templated transcription, initiation
BsBEST3136_23780	COG5002	protein histidine kinase activity
BsBEST3136_23790	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_23800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3136_23810	COG1333	cytochrome c biogenesis protein
BsBEST3136_23820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_23830	COG1187	pseudouridine synthase activity
BsBEST3136_23840	COG0700	Nucleoside recognition
BsBEST3136_23850	COG2715	membrane protein required for spore maturation
BsBEST3136_23860	COG1686	Belongs to the peptidase S11 family
BsBEST3136_23880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BsBEST3136_23890	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BsBEST3136_23900	COG1547	Domain of unknown function (DUF309)
BsBEST3136_23910	COG0456	acetyltransferase
BsBEST3136_23920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BsBEST3136_23930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3136_23930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3136_23940	COG0307	riboflavin synthase, alpha
BsBEST3136_23950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3136_23950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3136_23970	COG0681	Belongs to the peptidase S26 family
BsBEST3136_23990	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BsBEST3136_24020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BsBEST3136_24030	COG4086	secreted protein
BsBEST3136_24040	COG0019	diaminopimelate decarboxylase activity
BsBEST3136_24050	COG0697	spore germination
BsBEST3136_24080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3136_24120	COG1191	sigma factor activity
BsBEST3136_24130	COG2172	sigma factor antagonist activity
BsBEST3136_24140	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3136_24150	COG1686	Belongs to the peptidase S11 family
BsBEST3136_24160	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BsBEST3136_24170	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BsBEST3136_24180	COG4974	Belongs to the 'phage' integrase family
BsBEST3136_24200	COG0735	belongs to the Fur family
BsBEST3136_24210	COG1300	Membrane
BsBEST3136_24230	COG0281	malic enzyme
BsBEST3136_24240	COG1757	Na H antiporter
BsBEST3136_24250	COG1027	Aspartate ammonia-lyase
BsBEST3136_24260	COG0252	asparaginase activity
BsBEST3136_24270	COG1396	sequence-specific DNA binding
BsBEST3136_24280	COG1379	DNA repair
BsBEST3136_24290	COG0494	nUDIX hydrolase
BsBEST3136_24310	COG0667	Aldo Keto reductase
BsBEST3136_24330	COG1073	alpha beta
BsBEST3136_24350	COG4918	Iron-sulphur cluster biosynthesis
BsBEST3136_24360	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BsBEST3136_24360	COG0456	acetyltransferase
BsBEST3136_24370	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3136_24380	COG0456	acetyltransferase
BsBEST3136_24400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3136_24420	COG2211	Major facilitator Superfamily
BsBEST3136_24440	COG0346	lactoylglutathione lyase activity
BsBEST3136_24450	COG1072	(Pantothenic acid kinase))
BsBEST3136_24460	COG3048	D-serine ammonia-lyase activity
BsBEST3136_24470	COG0300	oxidoreductase activity
BsBEST3136_24480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3136_24490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3136_24500	COG4187	Peptidase family M20/M25/M40
BsBEST3136_24510	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3136_24520	COG0596	Alpha beta hydrolase
BsBEST3136_24530	COG1234	tRNA 3'-trailer cleavage
BsBEST3136_24540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BsBEST3136_24550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3136_24560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3136_24580	COG0706	membrane insertase activity
BsBEST3136_24590	COG3361	conserved protein (COG2071)
BsBEST3136_24600	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3136_24610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3136_24620	COG0346	lactoylglutathione lyase activity
BsBEST3136_24630	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3136_24640	COG4129	membrane
BsBEST3136_24650	COG1126	abc transporter atp-binding protein
BsBEST3136_24660	COG0765	amino acid transport
BsBEST3136_24670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3136_24690	COG1597	lipid kinase activity
BsBEST3136_24700	COG2814	Major facilitator Superfamily
BsBEST3136_24710	COG4978	Transcriptional regulator
BsBEST3136_24710	COG0789	Transcriptional regulator
BsBEST3136_24720	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3136_24730	COG0022	dehydrogenase e1 component
BsBEST3136_24740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3136_24750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3136_24760	COG3426	butyrate kinase activity
BsBEST3136_24770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3136_24780	COG0280	phosphate acetyltransferase
BsBEST3136_24790	COG3290	protein histidine kinase activity
BsBEST3136_24790	COG3829	transcription factor binding
BsBEST3136_24810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BsBEST3136_24820	COG2079	MmgE PrpD family protein
BsBEST3136_24830	COG0372	Belongs to the citrate synthase family
BsBEST3136_24840	COG1960	acyl-CoA dehydrogenase activity
BsBEST3136_24850	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3136_24860	COG0183	Belongs to the thiolase family
BsBEST3136_24870	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3136_24880	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_24900	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3136_24910	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_24920	COG0750	zinc metalloprotease
BsBEST3136_24930	COG0497	DNA recombination
BsBEST3136_24940	COG1438	arginine binding
BsBEST3136_24950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BsBEST3136_24960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BsBEST3136_24970	COG0142	geranyltranstransferase activity
BsBEST3136_24980	COG1722	exodeoxyribonuclease VII activity
BsBEST3136_24990	COG1570	exodeoxyribonuclease VII activity
BsBEST3136_25000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BsBEST3136_25010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3136_25020	COG1302	Protein conserved in bacteria
BsBEST3136_25030	COG0439	Biotin carboxylase
BsBEST3136_25040	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3136_25120	COG3854	ATPases associated with a variety of cellular activities
BsBEST3136_25140	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BsBEST3136_25150	COG0006	proline dipeptidase activity
BsBEST3136_25160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BsBEST3136_25180	COG3872	metal-dependent enzyme
BsBEST3136_25200	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3136_25210	COG1321	iron dependent repressor
BsBEST3136_25220	COG0095	Lipoate-protein ligase
BsBEST3136_25230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3136_25240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3136_25250	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3136_25260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BsBEST3136_25270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3136_25300	COG1396	sequence-specific DNA binding
BsBEST3136_25320	COG0681	Belongs to the peptidase S26 family
BsBEST3136_25370	COG4940	Competence protein ComGF
BsBEST3136_25390	COG4970	Tfp pilus assembly protein FimT
BsBEST3136_25400	COG4537	Required for transformation and DNA binding
BsBEST3136_25410	COG1459	type II secretion system
BsBEST3136_25420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BsBEST3136_25430	COG0598	Magnesium transport protein CorA
BsBEST3136_25440	COG1253	flavin adenine dinucleotide binding
BsBEST3136_25450	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3136_25460	COG1393	Belongs to the ArsC family
BsBEST3136_25480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3136_25500	COG0011	TIGRFAM Protein of
BsBEST3136_25520	COG2866	Carboxypeptidase
BsBEST3136_25530	COG1368	sulfuric ester hydrolase activity
BsBEST3136_25540	COG1940	carbohydrate kinase activity
BsBEST3136_25550	COG4483	Protein conserved in bacteria
BsBEST3136_25560	COG0705	Rhomboid family
BsBEST3136_25560	COG0457	Tetratricopeptide repeat
BsBEST3136_25580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BsBEST3136_25600	COG0438	transferase activity, transferring glycosyl groups
BsBEST3136_25630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3136_25640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3136_25650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3136_25660	COG0581	inorganic phosphate transmembrane transporter activity
BsBEST3136_25670	COG0573	inorganic phosphate transmembrane transporter activity
BsBEST3136_25680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BsBEST3136_25690	COG0768	penicillin binding
BsBEST3136_25700	COG0477	Major facilitator Superfamily
BsBEST3136_25710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3136_25720	COG2839	Protein conserved in bacteria
BsBEST3136_25730	COG5521	maltodextrose utilization protein MalA
BsBEST3136_25750	COG1388	LysM domain
BsBEST3136_25760	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BsBEST3136_25770	COG4709	membrane
BsBEST3136_25780	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BsBEST3136_25790	COG0735	belongs to the Fur family
BsBEST3136_25800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3136_25820	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BsBEST3136_25830	COG0513	Belongs to the DEAD box helicase family
BsBEST3136_25850	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BsBEST3136_25860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BsBEST3136_25870	COG2384	SAM-dependent methyltransferase
BsBEST3136_25880	COG2010	Cytochrome c
BsBEST3136_25890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BsBEST3136_25900	COG0358	DNA primase activity
BsBEST3136_25910	COG1671	Belongs to the UPF0178 family
BsBEST3136_25920	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BsBEST3136_25930	COG0517	IMP dehydrogenase activity
BsBEST3136_25940	COG0751	glycine-tRNA ligase activity
BsBEST3136_25950	COG0752	glycyl-tRNA synthetase alpha subunit
BsBEST3136_25960	COG1381	Involved in DNA repair and RecF pathway recombination
BsBEST3136_25980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BsBEST3136_25990	COG0295	cytidine deaminase activity
BsBEST3136_26000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BsBEST3136_26010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BsBEST3136_26020	COG1480	7TM receptor with intracellular HD hydrolase
BsBEST3136_26030	COG1702	phosphate starvation-inducible protein PhoH
BsBEST3136_26040	COG0561	phosphatase activity
BsBEST3136_26070	COG4864	UPF0365 protein
BsBEST3136_26080	COG1030	water channel activity
BsBEST3136_26090	COG1610	YqeY-like protein
BsBEST3136_26110	COG1283	sodium-dependent phosphate transmembrane transporter activity
BsBEST3136_26120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3136_26130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BsBEST3136_26140	COG2264	protein methyltransferase activity
BsBEST3136_26150	COG0484	heat shock protein binding
BsBEST3136_26160	COG0443	Heat shock 70 kDa protein
BsBEST3136_26170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BsBEST3136_26180	COG1420	regulation of RNA biosynthetic process
BsBEST3136_26190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3136_26200	COG0481	GTPase activity
BsBEST3136_26220	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_26230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BsBEST3136_26250	COG0268	Binds directly to 16S ribosomal RNA
BsBEST3136_26260	COG1466	dna polymerase III delta subunit
BsBEST3136_26280	COG0658	competence protein
BsBEST3136_26280	COG2333	competence protein COMEC
BsBEST3136_26300	COG2131	deaminase
BsBEST3136_26310	COG1555	photosystem II stabilization
BsBEST3136_26310	COG1596	polysaccharide export
BsBEST3136_26320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3136_26330	COG2226	methyltransferase
BsBEST3136_26340	COG0799	negative regulation of ribosome biogenesis
BsBEST3136_26350	COG1713	HD superfamily hydrolase involved in NAD metabolism
BsBEST3136_26360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BsBEST3136_26370	COG1534	Rna-binding protein
BsBEST3136_26380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BsBEST3136_26390	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3136_26400	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BsBEST3136_26410	COG2755	lipolytic protein G-D-S-L family
BsBEST3136_26420	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_26420	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_26430	COG0398	Pfam SNARE associated Golgi protein
BsBEST3136_26440	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BsBEST3136_26460	COG3209	COG3209 Rhs family protein
BsBEST3136_26480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3136_26500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3136_26510	COG0798	PFAM Bile acid sodium symporter
BsBEST3136_26520	COG0346	lactoylglutathione lyase activity
BsBEST3136_26530	COG0640	Transcriptional regulator
BsBEST3136_26540	COG3403	YqcI/YcgG family
BsBEST3136_26550	COG0457	Tetratricopeptide repeat
BsBEST3136_26580	COG5444	nuclease activity
BsBEST3136_26630	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_26630	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_26640	COG4824	toxin secretion phage lysis holin
BsBEST3136_26700	COG3778	Protein conserved in bacteria
BsBEST3136_26710	COG3299	homolog of phage Mu protein gp47
BsBEST3136_26720	COG3628	GPW Gp25 family protein
BsBEST3136_26740	COG4193	domain, Protein
BsBEST3136_26750	COG1652	LysM domain
BsBEST3136_26760	COG5280	Phage tail tape measure protein TP901
BsBEST3136_26760	COG3953	SLT domain
BsBEST3136_26890	COG4653	Phage capsid family
BsBEST3136_26900	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3136_26920	COG2369	cell adhesion
BsBEST3136_26930	COG5518	Phage portal protein
BsBEST3136_26940	COG1783	phage Terminase large subunit
BsBEST3136_26950	COG5484	DNA packaging
BsBEST3136_26970	COG3677	Transposase
BsBEST3136_27000	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BsBEST3136_27020	COG1484	DNA-dependent DNA replication
BsBEST3136_27030	COG3935	DnaD domain protein
BsBEST3136_27040	COG3723	Recombinational DNA repair protein, rece pathway
BsBEST3136_27050	COG5377	YqaJ viral recombinase family
BsBEST3136_27110	COG1476	TRANSCRIPTIONal
BsBEST3136_27120	COG3620	sequence-specific DNA binding
BsBEST3136_27140	COG0563	adenylate kinase activity
BsBEST3136_27150	COG2856	Zn peptidase
BsBEST3136_27170	COG3223	Belongs to the PsiE family
BsBEST3136_27180	COG0642	Histidine kinase
BsBEST3136_27180	COG5002	protein histidine kinase activity
BsBEST3136_27190	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_27200	COG2311	Membrane
BsBEST3136_27210	COG0454	-acetyltransferase
BsBEST3136_27220	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3136_27240	COG0730	response to heat
BsBEST3136_27250	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3136_27260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3136_27260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3136_27270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3136_27270	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3136_27280	COG2210	Belongs to the sulfur carrier protein TusA family
BsBEST3136_27290	COG1937	Protein conserved in bacteria
BsBEST3136_27320	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3136_27340	COG4978	Transcriptional regulator
BsBEST3136_27340	COG0789	Transcriptional regulator
BsBEST3136_27350	COG2814	Major facilitator Superfamily
BsBEST3136_27360	COG0456	acetyltransferase
BsBEST3136_27370	COG1253	flavin adenine dinucleotide binding
BsBEST3136_27390	COG0697	spore germination
BsBEST3136_27400	COG0583	DNA-binding transcription factor activity
BsBEST3136_27410	COG2072	flavoprotein involved in K transport
BsBEST3136_27420	COG1230	cation diffusion facilitator family transporter
BsBEST3136_27430	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3136_27440	COG0583	DNA-binding transcription factor activity
BsBEST3136_27460	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3136_27470	COG1687	branched-chain amino acid
BsBEST3136_27480	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BsBEST3136_27490	COG1522	sequence-specific DNA binding
BsBEST3136_27500	COG2732	(Barnase) inhibitor
BsBEST3136_27510	COG2124	cytochrome p450
BsBEST3136_27540	COG1335	isochorismatase
BsBEST3136_27560	COG2318	DinB family
BsBEST3136_27580	COG2070	2-Nitropropane dioxygenase
BsBEST3136_27610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3136_27640	COG3443	Belongs to the bacterial solute-binding protein 9 family
BsBEST3136_27650	COG1595	DNA-templated transcription, initiation
BsBEST3136_27660	COG0667	Aldo Keto reductase
BsBEST3136_27670	COG2851	Citrate transporter
BsBEST3136_27680	COG0583	DNA-binding transcription factor activity
BsBEST3136_27690	COG2828	Protein conserved in bacteria
BsBEST3136_27710	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_27720	COG5566	PFAM Mor transcription activator
BsBEST3136_27730	COG0596	Alpha beta hydrolase
BsBEST3136_27740	COG4991	sh3 domain protein
BsBEST3136_27750	COG4991	sh3 domain protein
BsBEST3136_27760	COG0346	lactoylglutathione lyase activity
BsBEST3136_27780	COG5577	PFAM Coat F domain
BsBEST3136_27790	COG1063	alcohol dehydrogenase
BsBEST3136_27810	COG5577	PFAM Coat F domain
BsBEST3136_27820	COG0789	Transcriptional regulator
BsBEST3136_27840	COG1064	alcohol dehydrogenase
BsBEST3136_27850	COG0693	protein deglycase activity
BsBEST3136_27860	COG1621	beta-fructofuranosidase activity
BsBEST3136_27870	COG3716	PTS system mannose fructose sorbose family IID component
BsBEST3136_27880	COG3715	PTS system
BsBEST3136_27890	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3136_27900	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3136_27910	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3136_27910	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BsBEST3136_27920	COG1113	amino acid transport
BsBEST3136_27930	COG1280	lysine exporter protein (LysE YggA)
BsBEST3136_27940	COG1378	Sugar-specific transcriptional regulator TrmB
BsBEST3136_27950	COG1595	DNA-templated transcription, initiation
BsBEST3136_27970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BsBEST3136_27970	COG2755	lipolytic protein G-D-S-L family
BsBEST3136_27990	COG2124	cytochrome p450
BsBEST3136_27990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3136_28000	COG1309	transcriptional regulator
BsBEST3136_28010	COG2226	methyltransferase
BsBEST3136_28030	COG2116	formate transmembrane transporter activity
BsBEST3136_28040	COG5609	conserved protein (DUF2294)
BsBEST3136_28050	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3136_28060	COG2427	Protein of unknown function (DUF1641)
BsBEST3136_28080	COG0626	cystathionine gamma-synthase activity
BsBEST3136_28090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3136_28100	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BsBEST3136_28110	COG2226	methyltransferase
BsBEST3136_28140	COG0768	penicillin binding
BsBEST3136_28150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BsBEST3136_28160	COG0572	uridine kinase
BsBEST3136_28170	COG0826	peptidase U32
BsBEST3136_28180	COG0826	peptidase U32
BsBEST3136_28190	COG4122	O-methyltransferase activity
BsBEST3136_28200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3136_28210	COG3906	Belongs to the UPF0473 family
BsBEST3136_28220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BsBEST3136_28230	COG4472	Bacterial protein of unknown function (DUF965)
BsBEST3136_28240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BsBEST3136_28250	COG0628	permease
BsBEST3136_28260	COG1126	abc transporter atp-binding protein
BsBEST3136_28270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3136_28280	COG0765	amino acid transport
BsBEST3136_28290	COG0765	amino acid transport
BsBEST3136_28320	COG3881	PFAM PRC-barrel domain
BsBEST3136_28330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BsBEST3136_28340	COG0457	Tetratricopeptide repeat
BsBEST3136_28350	COG0482	sulfurtransferase activity
BsBEST3136_28360	COG1104	cysteine desulfurase activity
BsBEST3136_28370	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3136_28380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BsBEST3136_28390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BsBEST3136_28400	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BsBEST3136_28410	COG0124	histidyl-tRNA synthetase
BsBEST3136_28430	COG4991	sh3 domain protein
BsBEST3136_28430	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_28430	COG3103	Sh3 type 3 domain protein
BsBEST3136_28440	COG1490	D-aminoacyl-tRNA deacylase activity
BsBEST3136_28450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BsBEST3136_28460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3136_28470	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BsBEST3136_28470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3136_28480	COG5416	Lipopolysaccharide assembly protein A domain
BsBEST3136_28490	COG0490	domain, Protein
BsBEST3136_28500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3136_28500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3136_28520	COG2244	polysaccharide biosynthetic process
BsBEST3136_28530	COG2323	membrane
BsBEST3136_28550	COG1862	Preprotein translocase
BsBEST3136_28560	COG0343	queuine tRNA-ribosyltransferase activity
BsBEST3136_28570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BsBEST3136_28590	COG2255	four-way junction helicase activity
BsBEST3136_28600	COG0632	four-way junction helicase activity
BsBEST3136_28620	COG2814	Major facilitator Superfamily
BsBEST3136_28630	COG0673	inositol 2-dehydrogenase activity
BsBEST3136_28640	COG2112	serine threonine protein kinase
BsBEST3136_28680	COG1115	amino acid carrier protein
BsBEST3136_28690	COG0217	transcriptional regulatory protein
BsBEST3136_28710	COG1388	LysM domain
BsBEST3136_28720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BsBEST3136_28730	COG0157	Belongs to the NadC ModD family
BsBEST3136_28740	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BsBEST3136_28750	COG1104	cysteine desulfurase activity
BsBEST3136_28760	COG1827	regulation of RNA biosynthetic process
BsBEST3136_28770	COG0077	Prephenate dehydratase
BsBEST3136_28780	COG4492	Belongs to the UPF0735 family
BsBEST3136_28790	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BsBEST3136_28800	COG3290	protein histidine kinase activity
BsBEST3136_28810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BsBEST3136_28820	COG2868	ribosomal protein
BsBEST3136_28830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BsBEST3136_28840	COG1994	Peptidase M50
BsBEST3136_28850	COG0739	heme binding
BsBEST3136_28860	COG2894	cell division
BsBEST3136_28870	COG0850	regulation of cytokinetic process
BsBEST3136_28880	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BsBEST3136_28900	COG1077	Cell shape determining protein MreB Mrl
BsBEST3136_28910	COG2003	Belongs to the UPF0758 family
BsBEST3136_28920	COG0424	maF-like protein
BsBEST3136_28940	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BsBEST3136_28950	COG0285	dihydrofolate synthase activity
BsBEST3136_28960	COG0525	valine-tRNA ligase activity
BsBEST3136_28980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3136_28990	COG1388	LysM domain
BsBEST3136_29000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3136_29010	COG0113	porphobilinogen synthase activity
BsBEST3136_29020	COG1587	Uroporphyrinogen-III synthase
BsBEST3136_29030	COG0181	hydroxymethylbilane synthase activity
BsBEST3136_29040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3136_29050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BsBEST3136_29070	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BsBEST3136_29080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BsBEST3136_29090	COG1067	ATP-dependent peptidase activity
BsBEST3136_29090	COG0470	DNA polymerase III
BsBEST3136_29100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BsBEST3136_29110	COG0544	peptidyl-prolyl cis-trans isomerase activity
BsBEST3136_29120	COG0457	Tetratricopeptide repeat
BsBEST3136_29120	COG1477	protein flavinylation
BsBEST3136_29130	COG0066	3-isopropylmalate dehydratase activity
BsBEST3136_29140	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BsBEST3136_29150	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3136_29160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3136_29170	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BsBEST3136_29180	COG0440	acetolactate synthase activity
BsBEST3136_29190	COG0028	Belongs to the TPP enzyme family
BsBEST3136_29210	COG0454	-acetyltransferase
BsBEST3136_29220	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BsBEST3136_29230	COG0622	Phosphoesterase
BsBEST3136_29240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BsBEST3136_29250	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BsBEST3136_29260	COG5401	PFAM Sporulation and spore germination
BsBEST3136_29270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3136_29280	COG1846	Transcriptional regulator
BsBEST3136_29290	COG2197	response regulator
BsBEST3136_29300	COG0824	Thioesterase
BsBEST3136_29310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BsBEST3136_29320	COG1053	succinate dehydrogenase
BsBEST3136_29330	COG2009	succinate dehydrogenase
BsBEST3136_29340	COG1719	4-vinyl reductase, 4VR
BsBEST3136_29350	COG0527	aspartate kinase activity
BsBEST3136_29360	COG0322	excinuclease ABC activity
BsBEST3136_29370	COG3118	belongs to the thioredoxin family
BsBEST3136_29380	COG3534	alpha-L-arabinofuranosidase
BsBEST3136_29390	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BsBEST3136_29400	COG2086	electron transfer activity
BsBEST3136_29410	COG1024	Enoyl-CoA hydratase
BsBEST3136_29420	COG1309	transcriptional regulator
BsBEST3136_29430	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3136_29440	COG3766	membrane
BsBEST3136_29450	COG1193	negative regulation of DNA recombination
BsBEST3136_29460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3136_29460	COG1796	DNA polymerase
BsBEST3136_29470	COG1286	toxin biosynthetic process
BsBEST3136_29480	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BsBEST3136_29490	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3136_29500	COG0072	phenylalanine-tRNA ligase activity
BsBEST3136_29500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3136_29510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BsBEST3136_29520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3136_29540	COG3835	regulator
BsBEST3136_29550	COG0277	FAD linked oxidase domain protein
BsBEST3136_29560	COG0247	lactate metabolic process
BsBEST3136_29570	COG0346	lactoylglutathione lyase activity
BsBEST3136_29590	COG1966	Carbon starvation protein
BsBEST3136_29600	COG3534	alpha-L-arabinofuranosidase
BsBEST3136_29610	COG0395	ABC-type sugar transport system, permease component
BsBEST3136_29620	COG1175	transmembrane transport
BsBEST3136_29630	COG1653	transport
BsBEST3136_29640	COG0371	Dehydrogenase
BsBEST3136_29650	COG0647	UMP catabolic process
BsBEST3136_29660	COG0235	Class ii aldolase
BsBEST3136_29670	COG1069	ribulokinase activity
BsBEST3136_29680	COG2160	L-arabinose isomerase activity
BsBEST3136_29690	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3136_29700	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3136_29710	COG1363	Peptidase, m42
BsBEST3136_29730	COG3326	Membrane
BsBEST3136_29740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BsBEST3136_29750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BsBEST3136_29760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BsBEST3136_29780	COG1346	cytolysis
BsBEST3136_29790	COG1380	Effector of murein hydrolase LrgA
BsBEST3136_29800	COG3279	Response regulator of the LytR AlgR family
BsBEST3136_29810	COG3275	phosphorelay sensor kinase activity
BsBEST3136_29820	COG1011	Hydrolase
BsBEST3136_29830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3136_29850	COG0398	Pfam SNARE associated Golgi protein
BsBEST3136_29860	COG1484	DNA-dependent DNA replication
BsBEST3136_29870	COG3611	Membrane attachment protein
BsBEST3136_29880	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BsBEST3136_29890	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BsBEST3136_29900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3136_29910	COG1733	regulation of RNA biosynthetic process
BsBEST3136_29920	COG2814	Major facilitator Superfamily
BsBEST3136_29930	COG0656	L-ascorbic acid biosynthetic process
BsBEST3136_29940	COG0237	dephospho-CoA kinase activity
BsBEST3136_29950	COG1971	Probably functions as a manganese efflux pump
BsBEST3136_29960	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BsBEST3136_29970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3136_29970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3136_29980	COG5002	protein histidine kinase activity
BsBEST3136_29990	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_30000	COG0039	L-malate dehydrogenase activity
BsBEST3136_30010	COG0538	isocitrate dehydrogenase activity
BsBEST3136_30020	COG0372	Belongs to the citrate synthase family
BsBEST3136_30030	COG2707	UPF0756 membrane protein
BsBEST3136_30040	COG0628	permease
BsBEST3136_30050	COG3030	protein affecting phage T7 exclusion by the F plasmid
BsBEST3136_30060	COG0469	pyruvate kinase activity
BsBEST3136_30070	COG0205	6-phosphofructokinase activity
BsBEST3136_30080	COG0825	malonyl-CoA metabolic process
BsBEST3136_30090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BsBEST3136_30100	COG0281	malic enzyme
BsBEST3136_30110	COG0587	DNA-directed DNA polymerase activity
BsBEST3136_30150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BsBEST3136_30170	COG4109	DRTGG domain
BsBEST3136_30180	COG0730	response to heat
BsBEST3136_30190	COG1473	amidohydrolase
BsBEST3136_30200	COG0196	riboflavin kinase activity
BsBEST3136_30210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3136_30220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BsBEST3136_30230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3136_30240	COG1126	abc transporter atp-binding protein
BsBEST3136_30250	COG0765	amino acid transport
BsBEST3136_30260	COG0765	amino acid transport
BsBEST3136_30270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3136_30280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3136_30290	COG0454	-acetyltransferase
BsBEST3136_30300	COG0583	DNA-binding transcription factor activity
BsBEST3136_30310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3136_30320	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_30340	COG0165	Argininosuccinate lyase
BsBEST3136_30350	COG0137	argininosuccinate synthase activity
BsBEST3136_30360	COG0521	Mo-molybdopterin cofactor biosynthetic process
BsBEST3136_30370	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BsBEST3136_30380	COG0827	DNA restriction-modification system
BsBEST3136_30390	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BsBEST3136_30400	COG3874	Sporulation protein YtfJ
BsBEST3136_30420	COG1714	RDD family
BsBEST3136_30430	COG0616	signal peptide processing
BsBEST3136_30440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3136_30450	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BsBEST3136_30460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3136_30480	COG0301	tRNA thio-modification
BsBEST3136_30490	COG1104	cysteine desulfurase activity
BsBEST3136_30500	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3136_30510	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BsBEST3136_30520	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3136_30530	COG1309	transcriptional regulator
BsBEST3136_30540	COG1956	GAF domain-containing protein
BsBEST3136_30550	COG2199	diguanylate cyclase activity
BsBEST3136_30550	COG2203	Gaf domain
BsBEST3136_30560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BsBEST3136_30580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3136_30590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3136_30600	COG0454	-acetyltransferase
BsBEST3136_30610	COG0517	IMP dehydrogenase activity
BsBEST3136_30620	COG0123	including yeast histone deacetylase and acetoin utilization protein
BsBEST3136_30630	COG1360	Flagellar Motor Protein
BsBEST3136_30640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3136_30650	COG1609	Transcriptional regulator
BsBEST3136_30660	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BsBEST3136_30660	COG1605	Chorismate mutase
BsBEST3136_30670	COG3118	belongs to the thioredoxin family
BsBEST3136_30680	COG4980	gas vesicle protein
BsBEST3136_30690	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3136_30700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BsBEST3136_30710	COG1674	ftsk spoiiie
BsBEST3136_30720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3136_30730	COG4848	Belongs to the UPF0354 family
BsBEST3136_30740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_30760	COG1363	Peptidase, m42
BsBEST3136_30770	COG5584	Small secreted protein
BsBEST3136_30780	COG0281	malic enzyme
BsBEST3136_30790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3136_30800	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BsBEST3136_30820	COG0510	thiamine kinase activity
BsBEST3136_30830	COG1523	belongs to the glycosyl hydrolase 13 family
BsBEST3136_30840	COG1597	lipid kinase activity
BsBEST3136_30860	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3136_30870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3136_30880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3136_30890	COG2252	PERMEase
BsBEST3136_30900	COG4473	ABC transporter
BsBEST3136_30910	COG1131	(ABC) transporter
BsBEST3136_30930	COG1349	DNA-binding transcription factor activity
BsBEST3136_30940	COG1187	pseudouridine synthase activity
BsBEST3136_30950	COG2244	polysaccharide biosynthetic process
BsBEST3136_30960	COG2081	HI0933 family
BsBEST3136_30970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BsBEST3136_30990	COG5578	integral membrane protein
BsBEST3136_31000	COG0673	inositol 2-dehydrogenase activity
BsBEST3136_31010	COG1653	transport
BsBEST3136_31020	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3136_31030	COG4209	transmembrane transport
BsBEST3136_31040	COG2207	Transcriptional regulator
BsBEST3136_31050	COG2207	Transcriptional regulator
BsBEST3136_31060	COG1653	transport
BsBEST3136_31070	COG0395	ABC-type sugar transport system, permease component
BsBEST3136_31080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3136_31090	COG2124	cytochrome p450
BsBEST3136_31100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BsBEST3136_31110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BsBEST3136_31120	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3136_31130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3136_31140	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BsBEST3136_31150	COG1073	alpha beta
BsBEST3136_31160	COG1609	Transcriptional regulator
BsBEST3136_31170	COG1653	transport
BsBEST3136_31180	COG1175	transmembrane transport
BsBEST3136_31190	COG0395	ABC-type sugar transport system, permease component
BsBEST3136_31200	COG1486	melibiose metabolic process
BsBEST3136_31210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3136_31220	COG0495	leucyl-tRNA aminoacylation
BsBEST3136_31240	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3136_31240	COG2202	Pas domain
BsBEST3136_31250	COG2814	Major facilitator Superfamily
BsBEST3136_31260	COG2433	Pfam Transposase IS66
BsBEST3136_31270	COG0577	efflux transmembrane transporter activity
BsBEST3136_31280	COG1136	(ABC) transporter
BsBEST3136_31290	COG2205	protein histidine kinase activity
BsBEST3136_31300	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_31310	COG0577	efflux transmembrane transporter activity
BsBEST3136_31320	COG1136	(ABC) transporter
BsBEST3136_31350	COG1131	(ABC) transporter
BsBEST3136_31360	COG1725	Transcriptional regulator
BsBEST3136_31380	COG1242	4 iron, 4 sulfur cluster binding
BsBEST3136_31390	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BsBEST3136_31410	COG2267	carboxylic ester hydrolase activity
BsBEST3136_31420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BsBEST3136_31430	COG1113	amino acid transport
BsBEST3136_31440	COG0367	asparagine synthase
BsBEST3136_31450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BsBEST3136_31460	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BsBEST3136_31480	COG1506	peptidase
BsBEST3136_31490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3136_31500	COG1116	anion transmembrane transporter activity
BsBEST3136_31510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3136_31520	COG0494	nUDIX hydrolase
BsBEST3136_31530	COG4824	toxin secretion phage lysis holin
BsBEST3136_31540	COG0783	Belongs to the Dps family
BsBEST3136_31570	COG1854	S-ribosylhomocysteine lyase activity
BsBEST3136_31580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BsBEST3136_31590	COG0288	reversible hydration of carbon dioxide
BsBEST3136_31600	COG0254	rRNA binding
BsBEST3136_31610	COG1271	oxidase subunit
BsBEST3136_31620	COG1294	oxidase, subunit
BsBEST3136_31640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3136_31650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3136_31650	COG1321	iron dependent repressor
BsBEST3136_31660	COG1121	(ABC) transporter
BsBEST3136_31670	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3136_31680	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3136_31690	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3136_31700	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BsBEST3136_31710	COG0596	Alpha beta hydrolase
BsBEST3136_31720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BsBEST3136_31730	COG1169	isochorismate synthase
BsBEST3136_31740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3136_31750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3136_31760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3136_31770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3136_31780	COG0438	transferase activity, transferring glycosyl groups
BsBEST3136_31800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3136_31810	COG0438	transferase activity, transferring glycosyl groups
BsBEST3136_31820	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3136_31830	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BsBEST3136_31840	COG0058	SHG alpha-glucan phosphorylase activity
BsBEST3136_31850	COG0297	glycogen (starch) synthase activity
BsBEST3136_31860	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3136_31870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3136_31880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BsBEST3136_31890	COG3859	Proton-coupled thiamine transporter YuaJ
BsBEST3136_31900	COG1247	-acetyltransferase
BsBEST3136_31910	COG2268	Band 7 protein
BsBEST3136_31920	COG1585	Membrane protein implicated in regulation of membrane protease activity
BsBEST3136_31930	COG2318	DinB family
BsBEST3136_31950	COG1454	alcohol dehydrogenase
BsBEST3136_31960	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_31970	COG1510	regulation of RNA biosynthetic process
BsBEST3136_31990	COG0569	domain protein
BsBEST3136_32000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3136_32010	COG4682	membrane
BsBEST3136_32020	COG1705	Flagellar rod assembly protein muramidase FlgJ
BsBEST3136_32030	COG0477	Major facilitator Superfamily
BsBEST3136_32040	COG5553	Cysteine dioxygenase type I
BsBEST3136_32050	COG1968	undecaprenyl-diphosphatase activity
BsBEST3136_32060	COG0628	permease
BsBEST3136_32070	COG0673	inositol 2-dehydrogenase activity
BsBEST3136_32080	COG4806	L-rhamnose isomerase
BsBEST3136_32090	COG3254	rhamnose metabolic process
BsBEST3136_32100	COG1070	Carbohydrate kinase
BsBEST3136_32110	COG1349	DNA-binding transcription factor activity
BsBEST3136_32120	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_32120	COG3347	Dehydrogenase
BsBEST3136_32130	COG0840	transmembrane signaling receptor activity
BsBEST3136_32140	COG0840	transmembrane signaling receptor activity
BsBEST3136_32160	COG0840	transmembrane signaling receptor activity
BsBEST3136_32170	COG0840	transmembrane signaling receptor activity
BsBEST3136_32200	COG0432	Pfam Uncharacterised protein family UPF0047
BsBEST3136_32220	COG0366	Alpha amylase catalytic
BsBEST3136_32230	COG1253	flavin adenine dinucleotide binding
BsBEST3136_32240	COG2738	Putative neutral zinc metallopeptidase
BsBEST3136_32270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BsBEST3136_32300	COG0166	Belongs to the GPI family
BsBEST3136_32310	COG1979	alcohol dehydrogenase
BsBEST3136_32320	COG1979	alcohol dehydrogenase
BsBEST3136_32330	COG2155	Conserved Protein
BsBEST3136_32340	COG1098	S1 RNA binding domain
BsBEST3136_32350	COG0436	Aminotransferase
BsBEST3136_32360	COG1522	sequence-specific DNA binding
BsBEST3136_32370	COG2267	carboxylic ester hydrolase activity
BsBEST3136_32390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BsBEST3136_32400	COG2205	protein histidine kinase activity
BsBEST3136_32420	COG5018	Exonuclease
BsBEST3136_32440	COG2814	Major facilitator Superfamily
BsBEST3136_32450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3136_32460	COG3011	Protein conserved in bacteria
BsBEST3136_32480	COG3290	protein histidine kinase activity
BsBEST3136_32490	COG4565	transcriptional regulatory protein
BsBEST3136_32500	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3136_32510	COG3845	ABC transporter
BsBEST3136_32520	COG4603	Belongs to the binding-protein-dependent transport system permease family
BsBEST3136_32530	COG1079	Belongs to the binding-protein-dependent transport system permease family
BsBEST3136_32540	COG3493	citrate carrier protein
BsBEST3136_32560	COG2111	Na H antiporter
BsBEST3136_32560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3136_32570	COG2111	Na H antiporter
BsBEST3136_32580	COG1006	Multisubunit Na H antiporter MnhC subunit
BsBEST3136_32590	COG0651	ATP synthesis coupled electron transport
BsBEST3136_32600	COG1863	multisubunit Na H antiporter MnhE subunit
BsBEST3136_32610	COG2212	antiporter activity
BsBEST3136_32620	COG1320	monovalent cation:proton antiporter activity
BsBEST3136_32630	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3136_32640	COG2197	response regulator
BsBEST3136_32650	COG4585	Histidine kinase
BsBEST3136_32670	COG0142	geranyltranstransferase activity
BsBEST3136_32700	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BsBEST3136_32710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BsBEST3136_32720	COG1335	isochorismatase
BsBEST3136_32730	COG5506	Protein of unknown function (DUF1694)
BsBEST3136_32760	COG0628	permease
BsBEST3136_32780	COG1418	mRNA catabolic process
BsBEST3136_32790	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_32810	COG1511	domain protein
BsBEST3136_32820	COG0433	COG0433 Predicted ATPase
BsBEST3136_32820	COG1674	ftsk spoiiie
BsBEST3136_32830	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3136_32840	COG5417	Belongs to the EsaB family
BsBEST3136_32850	COG4842	Belongs to the WXG100 family
BsBEST3136_32860	COG2508	Transcriptional regulator
BsBEST3136_32860	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3136_32870	COG0686	Belongs to the AlaDH PNT family
BsBEST3136_32880	COG5634	Uncharacterized conserved protein (DUF2278)
BsBEST3136_32890	COG3251	PFAM MbtH domain protein
BsBEST3136_32900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_32910	COG3433	isochorismatase activity
BsBEST3136_32910	COG1535	isochorismatase
BsBEST3136_32920	COG1021	2,3-dihydroxybenzoate-AMP ligase
BsBEST3136_32930	COG1169	isochorismate synthase
BsBEST3136_32940	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_32950	COG2819	hydrolase of the alpha beta superfamily
BsBEST3136_32960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3136_32970	COG1268	BioY protein
BsBEST3136_32980	COG2056	Na+-H+ antiporter family
BsBEST3136_32990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BsBEST3136_33000	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BsBEST3136_33010	COG3584	3D domain protein
BsBEST3136_33030	COG1252	NADH dehydrogenase
BsBEST3136_33040	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3136_33060	COG0516	GMP reductase activity
BsBEST3136_33070	COG2808	Putative FMN-binding domain
BsBEST3136_33080	COG0456	acetyltransferase
BsBEST3136_33090	COG0316	Belongs to the HesB IscA family
BsBEST3136_33100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BsBEST3136_33110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3136_33120	COG4844	belongs to the
BsBEST3136_33130	COG1252	NADH dehydrogenase
BsBEST3136_33140	COG4837	Protein of unknown function (DUF1462)
BsBEST3136_33150	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BsBEST3136_33160	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3136_33160	COG4946	Tricorn protease homolog
BsBEST3136_33160	COG1506	peptidase
BsBEST3136_33170	COG0083	homoserine kinase activity
BsBEST3136_33180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BsBEST3136_33190	COG0460	homoserine dehydrogenase
BsBEST3136_33200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3136_33210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3136_33220	COG0647	UMP catabolic process
BsBEST3136_33230	COG2445	Protein of unknown function DUF86
BsBEST3136_33240	COG4470	Protein conserved in bacteria
BsBEST3136_33260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BsBEST3136_33270	COG0739	heme binding
BsBEST3136_33290	COG3377	Domain of unknown function (DUF1805)
BsBEST3136_33300	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3136_33310	COG0730	response to heat
BsBEST3136_33320	COG1801	Protein of unknown function DUF72
BsBEST3136_33340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3136_33350	COG2508	Transcriptional regulator
BsBEST3136_33360	COG2233	PERMEase
BsBEST3136_33370	COG2233	PERMEase
BsBEST3136_33380	COG3195	allantoin biosynthetic process
BsBEST3136_33380	COG3648	Uricase
BsBEST3136_33390	COG2351	hydroxyisourate hydrolase activity
BsBEST3136_33410	COG2080	2 iron, 2 sulfur cluster binding
BsBEST3136_33420	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BsBEST3136_33430	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BsBEST3136_33440	COG2068	MobA-Related Protein
BsBEST3136_33450	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BsBEST3136_33460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BsBEST3136_33470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3136_33480	COG2356	endonuclease I
BsBEST3136_33490	COG3842	ATPase activity
BsBEST3136_33500	COG2188	Transcriptional regulator
BsBEST3136_33510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3136_33520	COG0395	ABC-type sugar transport system, permease component
BsBEST3136_33530	COG1175	transmembrane transport
BsBEST3136_33540	COG1653	transport
BsBEST3136_33550	COG2222	sugar isomerase
BsBEST3136_33560	COG0322	excinuclease ABC activity
BsBEST3136_33570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3136_33600	COG0346	lactoylglutathione lyase activity
BsBEST3136_33610	COG0640	Transcriptional regulator
BsBEST3136_33620	COG0719	Fe-S assembly protein
BsBEST3136_33630	COG0822	iron-sulfur transferase activity
BsBEST3136_33640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3136_33650	COG0719	Fe-S assembly protein
BsBEST3136_33660	COG0396	ATPase activity
BsBEST3136_33680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3136_33690	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3136_33700	COG2011	ABC-type metal ion transport system permease component
BsBEST3136_33710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BsBEST3136_33730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3136_33740	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3136_33760	COG0509	glycine decarboxylation via glycine cleavage system
BsBEST3136_33770	COG1393	Belongs to the ArsC family
BsBEST3136_33780	COG1960	acyl-CoA dehydrogenase activity
BsBEST3136_33790	COG0183	Belongs to the thiolase family
BsBEST3136_33800	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3136_33800	COG1024	Enoyl-CoA hydratase
BsBEST3136_33820	COG0506	proline dehydrogenase activity
BsBEST3136_33840	COG5577	PFAM Coat F domain
BsBEST3136_33850	COG1846	Transcriptional regulator
BsBEST3136_33860	COG0477	Major facilitator Superfamily
BsBEST3136_33870	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3136_33880	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_33890	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_33900	COG0583	DNA-binding transcription factor activity
BsBEST3136_33920	COG1120	ATPase activity
BsBEST3136_33960	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_33970	COG0783	Belongs to the Dps family
BsBEST3136_33980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3136_33990	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_34000	COG2770	Histidine kinase
BsBEST3136_34000	COG2205	protein histidine kinase activity
BsBEST3136_34020	COG1309	transcriptional regulator
BsBEST3136_34030	COG0114	fumarate hydratase activity
BsBEST3136_34050	COG0697	spore germination
BsBEST3136_34060	COG0814	amino acid
BsBEST3136_34080	COG2197	response regulator
BsBEST3136_34090	COG4585	Histidine kinase
BsBEST3136_34100	COG4758	membrane
BsBEST3136_34110	COG3595	metallopeptidase activity
BsBEST3136_34120	COG1842	Phage shock protein A
BsBEST3136_34130	COG4758	membrane
BsBEST3136_34140	COG2814	Major facilitator Superfamily
BsBEST3136_34150	COG2096	Adenosyltransferase
BsBEST3136_34160	COG1120	ATPase activity
BsBEST3136_34170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3136_34180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3136_34190	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_34200	COG3386	PFAM SMP-30 Gluconolaconase
BsBEST3136_34210	COG2205	protein histidine kinase activity
BsBEST3136_34220	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_34240	COG1191	sigma factor activity
BsBEST3136_34260	COG2140	Oxalate decarboxylase
BsBEST3136_34280	COG0577	efflux transmembrane transporter activity
BsBEST3136_34290	COG1136	(ABC) transporter
BsBEST3136_34300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3136_34310	COG1120	ATPase activity
BsBEST3136_34320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3136_34330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3136_34340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3136_34350	COG0531	amino acid
BsBEST3136_34370	COG1988	membrane-bound metal-dependent
BsBEST3136_34380	COG1368	sulfuric ester hydrolase activity
BsBEST3136_34390	COG1910	domain protein
BsBEST3136_34400	COG0725	ABC transporter, periplasmic molybdate-binding protein
BsBEST3136_34410	COG4149	molybdate abc transporter
BsBEST3136_34420	COG0656	L-ascorbic acid biosynthetic process
BsBEST3136_34440	COG0025	NhaP-type Na H and K H
BsBEST3136_34450	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3136_34460	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3136_34470	COG3973	AAA domain
BsBEST3136_34480	COG2860	membrane
BsBEST3136_34490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3136_34500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BsBEST3136_34510	COG2217	Heavy metal translocating P-type atpase
BsBEST3136_34520	COG2217	Heavy metal translocating P-type atpase
BsBEST3136_34530	COG2608	mercury ion transmembrane transporter activity
BsBEST3136_34540	COG1937	Protein conserved in bacteria
BsBEST3136_34550	COG0673	inositol 2-dehydrogenase activity
BsBEST3136_34560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3136_34570	COG1289	transmembrane transporter activity
BsBEST3136_34590	COG2076	Multidrug Resistance protein
BsBEST3136_34600	COG1309	transcriptional regulator
BsBEST3136_34610	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_34620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BsBEST3136_34630	COG0557	exoribonuclease II activity
BsBEST3136_34640	COG1647	Serine aminopeptidase, S33
BsBEST3136_34650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3136_34660	COG0596	Alpha beta hydrolase
BsBEST3136_34670	COG1476	TRANSCRIPTIONal
BsBEST3136_34680	COG1396	sequence-specific DNA binding
BsBEST3136_34690	COG1396	sequence-specific DNA binding
BsBEST3136_34700	COG1733	regulation of RNA biosynthetic process
BsBEST3136_34710	COG0840	transmembrane signaling receptor activity
BsBEST3136_34720	COG1174	glycine betaine transport
BsBEST3136_34730	COG1732	Glycine betaine
BsBEST3136_34740	COG1174	glycine betaine transport
BsBEST3136_34750	COG0517	IMP dehydrogenase activity
BsBEST3136_34750	COG1125	glycine betaine transport
BsBEST3136_34760	COG1510	regulation of RNA biosynthetic process
BsBEST3136_34800	COG5658	integral membrane protein
BsBEST3136_34810	COG0640	Transcriptional regulator
BsBEST3136_34820	COG1174	glycine betaine transport
BsBEST3136_34830	COG1732	Glycine betaine
BsBEST3136_34840	COG1174	glycine betaine transport
BsBEST3136_34850	COG0517	IMP dehydrogenase activity
BsBEST3136_34850	COG1125	glycine betaine transport
BsBEST3136_34860	COG1510	regulation of RNA biosynthetic process
BsBEST3136_34870	COG2095	MarC family integral membrane protein
BsBEST3136_34890	COG3064	Membrane
BsBEST3136_34900	COG4640	response to antibiotic
BsBEST3136_34910	COG0456	acetyltransferase
BsBEST3136_34920	COG0148	phosphopyruvate hydratase activity
BsBEST3136_34930	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BsBEST3136_34940	COG0149	triose-phosphate isomerase activity
BsBEST3136_34950	COG0126	phosphoglycerate kinase activity
BsBEST3136_34960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3136_34970	COG2390	Transcriptional regulator
BsBEST3136_34980	COG2814	Major facilitator Superfamily
BsBEST3136_34990	COG1609	Transcriptional regulator
BsBEST3136_35000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3136_35010	COG0583	DNA-binding transcription factor activity
BsBEST3136_35020	COG0697	spore germination
BsBEST3136_35030	COG1113	amino acid transport
BsBEST3136_35040	COG3858	chitin binding
BsBEST3136_35050	COG1556	Lactate utilization protein
BsBEST3136_35060	COG1139	Iron-sulfur cluster binding protein
BsBEST3136_35070	COG0247	lactate metabolic process
BsBEST3136_35080	COG2197	response regulator
BsBEST3136_35090	COG4585	Histidine kinase
BsBEST3136_35100	COG0842	Transport permease protein
BsBEST3136_35110	COG1131	(ABC) transporter
BsBEST3136_35120	COG0596	Alpha beta hydrolase
BsBEST3136_35130	COG2208	phosphoserine phosphatase activity
BsBEST3136_35140	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BsBEST3136_35150	COG1874	Beta-galactosidase
BsBEST3136_35160	COG3833	ABC-type maltose transport systems, permease component
BsBEST3136_35170	COG1175	transmembrane transport
BsBEST3136_35180	COG2182	Extracellular solute-binding protein
BsBEST3136_35190	COG1609	Transcriptional regulator
BsBEST3136_35200	COG2186	Transcriptional regulator
BsBEST3136_35210	COG1620	l-lactate permease
BsBEST3136_35220	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BsBEST3136_35240	COG5039	Polysaccharide pyruvyl transferase
BsBEST3136_35250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3136_35260	COG0110	maltose O-acetyltransferase activity
BsBEST3136_35270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BsBEST3136_35280	COG2244	polysaccharide biosynthetic process
BsBEST3136_35290	COG1216	Glycosyl transferase, family 2
BsBEST3136_35300	COG5039	Polysaccharide pyruvyl transferase
BsBEST3136_35310	COG1216	Glycosyl transferase, family 2
BsBEST3136_35330	COG0438	transferase activity, transferring glycosyl groups
BsBEST3136_35340	COG1215	transferase activity, transferring glycosyl groups
BsBEST3136_35350	COG0438	transferase activity, transferring glycosyl groups
BsBEST3136_35360	COG1086	Polysaccharide biosynthesis protein
BsBEST3136_35370	COG0489	protein tyrosine kinase activity
BsBEST3136_35380	COG3944	biosynthesis protein
BsBEST3136_35390	COG1396	sequence-specific DNA binding
BsBEST3136_35400	COG2272	Belongs to the type-B carboxylesterase lipase family
BsBEST3136_35420	COG3479	Phenolic acid decarboxylase
BsBEST3136_35450	COG1794	racemase activity, acting on amino acids and derivatives
BsBEST3136_35460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3136_35470	COG1621	beta-fructofuranosidase activity
BsBEST3136_35480	COG1621	beta-fructofuranosidase activity
BsBEST3136_35490	COG0531	amino acid
BsBEST3136_35500	COG1309	transcriptional regulator
BsBEST3136_35510	COG2076	Multidrug Resistance protein
BsBEST3136_35520	COG2076	Multidrug Resistance protein
BsBEST3136_35540	COG0277	FAD linked oxidase domain protein
BsBEST3136_35550	COG3621	Patatin-like phospholipase
BsBEST3136_35560	COG0740	serine-type endopeptidase activity
BsBEST3136_35570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3136_35580	COG0366	Alpha amylase catalytic
BsBEST3136_35590	COG1554	hydrolase, family 65, central catalytic
BsBEST3136_35600	COG5521	maltodextrose utilization protein MalA
BsBEST3136_35610	COG3833	ABC-type maltose transport systems, permease component
BsBEST3136_35620	COG1175	transmembrane transport
BsBEST3136_35630	COG2182	Extracellular solute-binding protein
BsBEST3136_35650	COG1609	Transcriptional regulator
BsBEST3136_35660	COG1611	Belongs to the LOG family
BsBEST3136_35670	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3136_35680	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3136_35690	COG0288	reversible hydration of carbon dioxide
BsBEST3136_35700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3136_35710	COG0577	efflux transmembrane transporter activity
BsBEST3136_35720	COG1136	(ABC) transporter
BsBEST3136_35730	COG5002	protein histidine kinase activity
BsBEST3136_35740	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_35760	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BsBEST3136_35770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3136_35780	COG1481	regulation of sporulation
BsBEST3136_35790	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BsBEST3136_35800	COG1660	Displays ATPase and GTPase activities
BsBEST3136_35810	COG1051	belongs to the nudix hydrolase family
BsBEST3136_35820	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3136_35830	COG0791	NLP P60 protein
BsBEST3136_35830	COG3883	PFAM NLP P60 protein
BsBEST3136_35840	COG0457	Tetratricopeptide repeat
BsBEST3136_35850	COG1132	(ABC) transporter
BsBEST3136_35890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BsBEST3136_35890	COG0140	phosphoribosyl-ATP diphosphatase activity
BsBEST3136_35900	COG0107	imidazoleglycerol-phosphate synthase activity
BsBEST3136_35910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BsBEST3136_35920	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BsBEST3136_35930	COG0131	Imidazoleglycerol-phosphate dehydratase
BsBEST3136_35940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BsBEST3136_35950	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BsBEST3136_35960	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BsBEST3136_35970	COG4990	cell redox homeostasis
BsBEST3136_35980	COG5297	Belongs to the glycosyl hydrolase family 6
BsBEST3136_35990	COG0110	maltose O-acetyltransferase activity
BsBEST3136_36000	COG0546	phosphoglycolate phosphatase activity
BsBEST3136_36010	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BsBEST3136_36020	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BsBEST3136_36030	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BsBEST3136_36040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BsBEST3136_36050	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3136_36060	COG2188	Transcriptional regulator
BsBEST3136_36070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3136_36080	COG1846	Transcriptional regulator
BsBEST3136_36090	COG2124	cytochrome p450
BsBEST3136_36110	COG1846	Transcriptional regulator
BsBEST3136_36120	COG2814	Major facilitator Superfamily
BsBEST3136_36130	COG1950	PFAM Membrane protein of
BsBEST3136_36140	COG1983	PspC domain protein
BsBEST3136_36150	COG3595	metallopeptidase activity
BsBEST3136_36180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3136_36190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BsBEST3136_36200	COG0556	nucleotide-excision repair
BsBEST3136_36210	COG4897	Protein conserved in bacteria
BsBEST3136_36220	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3136_36220	COG3848	Pyruvate phosphate dikinase
BsBEST3136_36230	COG1309	transcriptional regulator
BsBEST3136_36240	COG2814	Major facilitator Superfamily
BsBEST3136_36250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3136_36270	COG0793	Belongs to the peptidase S41A family
BsBEST3136_36270	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3136_36280	COG2177	Part of the ABC transporter FtsEX involved in
BsBEST3136_36290	COG2884	Cell division ATP-binding protein ftsE
BsBEST3136_36300	COG2010	Cytochrome c
BsBEST3136_36310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3136_36320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BsBEST3136_36330	COG0653	protein targeting
BsBEST3136_36340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BsBEST3136_36360	COG1516	flagellar protein fliS
BsBEST3136_36370	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BsBEST3136_36380	COG1334	flagellar protein FlaG
BsBEST3136_36390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3136_36400	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BsBEST3136_36410	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BsBEST3136_36430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3136_36440	COG1256	bacterial-type flagellum assembly
BsBEST3136_36440	COG4786	Flagellar basal body rod
BsBEST3136_36450	COG3418	PFAM FlgN family protein
BsBEST3136_36460	COG2747	anti-sigma28 factor FlgM
BsBEST3136_36480	COG1040	competence protein
BsBEST3136_36500	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BsBEST3136_36510	COG1307	EDD domain protein, DegV family
BsBEST3136_36520	COG2197	response regulator
BsBEST3136_36530	COG4585	Histidine kinase
BsBEST3136_36540	COG1739	Uncharacterized protein family UPF0029
BsBEST3136_36550	COG1316	TRANSCRIPTIONal
BsBEST3136_36560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3136_36570	COG0438	transferase activity, transferring glycosyl groups
BsBEST3136_36580	COG1215	transferase activity, transferring glycosyl groups
BsBEST3136_36590	COG3206	protein involved in exopolysaccharide biosynthesis
BsBEST3136_36600	COG3307	-O-antigen
BsBEST3136_36610	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3136_36620	COG0297	glycogen (starch) synthase activity
BsBEST3136_36620	COG0438	transferase activity, transferring glycosyl groups
BsBEST3136_36630	COG2244	polysaccharide biosynthetic process
BsBEST3136_36660	COG2247	cell wall binding repeat
BsBEST3136_36660	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3136_36670	COG2247	cell wall binding repeat
BsBEST3136_36670	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3136_36690	COG1316	TRANSCRIPTIONal
BsBEST3136_36700	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BsBEST3136_36710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3136_36720	COG1215	transferase activity, transferring glycosyl groups
BsBEST3136_36720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3136_36730	COG0463	Glycosyl transferase, family 2
BsBEST3136_36750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3136_36760	COG1134	teichoic acid transport
BsBEST3136_36770	COG1682	transport, permease protein
BsBEST3136_36780	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3136_36790	COG0438	transferase activity, transferring glycosyl groups
BsBEST3136_36800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BsBEST3136_36810	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BsBEST3136_36820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3136_36840	COG4193	domain, Protein
BsBEST3136_36850	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3136_36860	COG0697	spore germination
BsBEST3136_36870	COG0814	amino acid
BsBEST3136_36890	COG2814	Major facilitator Superfamily
BsBEST3136_36900	COG1316	TRANSCRIPTIONal
BsBEST3136_36910	COG0561	phosphatase activity
BsBEST3136_36920	COG0791	NLP P60 protein
BsBEST3136_36940	COG2843	Capsule synthesis protein
BsBEST3136_36960	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3136_36970	COG1609	Transcriptional regulator
BsBEST3136_36980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3136_36990	COG1869	D-ribose catabolic process
BsBEST3136_37000	COG1129	ABC transporter
BsBEST3136_37010	COG1172	Belongs to the binding-protein-dependent transport system permease family
BsBEST3136_37020	COG1879	ABC-type sugar transport system periplasmic component
BsBEST3136_37030	COG3103	Sh3 type 3 domain protein
BsBEST3136_37050	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3136_37060	COG3527	Alpha-acetolactate decarboxylase
BsBEST3136_37070	COG0028	Belongs to the TPP enzyme family
BsBEST3136_37080	COG0583	DNA-binding transcription factor activity
BsBEST3136_37090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3136_37120	COG5337	Spore coat protein CotH
BsBEST3136_37140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3136_37160	COG0405	Gamma-glutamyltransferase
BsBEST3136_37170	COG1522	sequence-specific DNA binding
BsBEST3136_37180	COG2059	Chromate
BsBEST3136_37190	COG2059	Chromate
BsBEST3136_37210	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3136_37220	COG0583	DNA-binding transcription factor activity
BsBEST3136_37230	COG1515	deoxyribonuclease V activity
BsBEST3136_37240	COG2849	repeat protein
BsBEST3136_37250	COG5444	nuclease activity
BsBEST3136_37280	COG3878	Protein conserved in bacteria
BsBEST3136_37290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3136_37300	COG4464	protein tyrosine phosphatase activity
BsBEST3136_37310	COG0489	protein tyrosine kinase activity
BsBEST3136_37320	COG3944	biosynthesis protein
BsBEST3136_37340	COG4715	Zinc finger, swim domain protein
BsBEST3136_37350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3136_37360	COG0561	phosphatase activity
BsBEST3136_37370	COG1349	DNA-binding transcription factor activity
BsBEST3136_37380	COG0629	single-stranded DNA binding
BsBEST3136_37420	COG3764	Sortase (surface protein transpeptidase)
BsBEST3136_37440	COG2972	Histidine kinase
BsBEST3136_37440	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_37450	COG1970	mechanosensitive ion channel activity
BsBEST3136_37460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3136_37470	COG0457	Tetratricopeptide repeat
BsBEST3136_37480	COG4786	Flagellar basal body rod
BsBEST3136_37490	COG4786	Flagellar basal body rod
BsBEST3136_37500	COG1077	Cell shape determining protein MreB Mrl
BsBEST3136_37510	COG1609	Transcriptional regulator
BsBEST3136_37520	COG1846	Transcriptional regulator
BsBEST3136_37530	COG2814	Major facilitator Superfamily
BsBEST3136_37540	COG3420	alginic acid biosynthetic process
BsBEST3136_37550	COG1953	Uracil, thiamine, allantoin
BsBEST3136_37560	COG0477	Major facilitator Superfamily
BsBEST3136_37570	COG1335	isochorismatase
BsBEST3136_37590	COG0004	ammonium transporteR
BsBEST3136_37600	COG0347	Belongs to the P(II) protein family
BsBEST3136_37610	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3136_37630	COG0739	heme binding
BsBEST3136_37640	COG1247	-acetyltransferase
BsBEST3136_37660	COG2089	acid synthase
BsBEST3136_37680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3136_37690	COG0789	Transcriptional regulator
BsBEST3136_37710	COG2910	NAD(P)H-binding
BsBEST3136_37720	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3136_37730	COG0804	urea catabolic process
BsBEST3136_37740	COG0832	Belongs to the urease beta subunit family
BsBEST3136_37750	COG0831	urea catabolic process
BsBEST3136_37770	COG3237	CsbD-like
BsBEST3136_37780	COG1994	Peptidase M50
BsBEST3136_37790	COG0457	Tetratricopeptide repeat
BsBEST3136_37800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BsBEST3136_37810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BsBEST3136_37830	COG2304	oxidoreductase activity
BsBEST3136_37840	COG2304	oxidoreductase activity
BsBEST3136_37860	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3136_37870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3136_37890	COG4836	Membrane
BsBEST3136_37910	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BsBEST3136_37920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BsBEST3136_37930	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BsBEST3136_37940	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BsBEST3136_37950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BsBEST3136_37960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BsBEST3136_37980	COG0356	it plays a direct role in the translocation of protons across the membrane
BsBEST3136_38000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BsBEST3136_38010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BsBEST3136_38020	COG4475	Protein of unknown function (DUF436)
BsBEST3136_38030	COG0698	ribose 5-phosphate isomerase
BsBEST3136_38040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3136_38050	COG1971	Probably functions as a manganese efflux pump
BsBEST3136_38060	COG0009	L-threonylcarbamoyladenylate synthase
BsBEST3136_38070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BsBEST3136_38110	COG2890	protein-(glutamine-N5) methyltransferase activity
BsBEST3136_38120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BsBEST3136_38130	COG0346	lactoylglutathione lyase activity
BsBEST3136_38140	COG0789	Transcriptional regulator
BsBEST3136_38150	COG0679	Auxin Efflux Carrier
BsBEST3136_38160	COG0281	malic enzyme
BsBEST3136_38170	COG1435	thymidine kinase activity
BsBEST3136_38190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BsBEST3136_38200	COG1494	fructose-1,6-bisphosphatase
BsBEST3136_38210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3136_38220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BsBEST3136_38230	COG0191	fructose-bisphosphate aldolase activity
BsBEST3136_38240	COG2204	response regulator
BsBEST3136_38250	COG4821	SIS domain
BsBEST3136_38260	COG0504	CTP synthase activity
BsBEST3136_38270	COG3343	RNA polymerase activity
BsBEST3136_38280	COG1960	acyl-CoA dehydrogenase activity
BsBEST3136_38290	COG2181	nitrate reductase activity
BsBEST3136_38290	COG0247	lactate metabolic process
BsBEST3136_38300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3136_38310	COG4294	response to UV
BsBEST3136_38330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3136_38340	COG1132	(ABC) transporter
BsBEST3136_38350	COG1132	(ABC) transporter
BsBEST3136_38360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3136_38380	COG2181	nitrate reductase activity
BsBEST3136_38390	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BsBEST3136_38400	COG1140	nitrate reductase beta subunit
BsBEST3136_38410	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BsBEST3136_38420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3136_38440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3136_38450	COG2223	nitrite transmembrane transporter activity
BsBEST3136_38460	COG0018	arginyl-trna synthetase
BsBEST3136_38470	COG4506	Protein conserved in bacteria
BsBEST3136_38490	COG0535	radical SAM domain protein
BsBEST3136_38510	COG1131	(ABC) transporter
BsBEST3136_38520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3136_38530	COG0612	Peptidase, M16
BsBEST3136_38540	COG0612	Peptidase, M16
BsBEST3136_38560	COG3391	amine dehydrogenase activity
BsBEST3136_38570	COG3391	amine dehydrogenase activity
BsBEST3136_38580	COG0457	Tetratricopeptide repeat
BsBEST3136_38600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3136_38610	COG0010	Belongs to the arginase family
BsBEST3136_38620	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BsBEST3136_38630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3136_38650	COG1994	Peptidase M50
BsBEST3136_38660	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3136_38670	COG1846	Transcriptional regulator
BsBEST3136_38680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3136_38690	COG0477	Major facilitator Superfamily
BsBEST3136_38700	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3136_38710	COG3465	dGTPase activity
BsBEST3136_38720	COG1078	dGTPase activity
BsBEST3136_38730	COG4844	belongs to the
BsBEST3136_38750	COG0697	spore germination
BsBEST3136_38760	COG0095	Lipoate-protein ligase
BsBEST3136_38770	COG0583	DNA-binding transcription factor activity
BsBEST3136_38780	COG0280	phosphate acetyltransferase
BsBEST3136_38790	COG3253	May function as heme-dependent peroxidase
BsBEST3136_38800	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_38810	COG0436	Aminotransferase
BsBEST3136_38820	COG2814	Major facilitator Superfamily
BsBEST3136_38830	COG0151	Belongs to the GarS family
BsBEST3136_38840	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_38850	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3136_38860	COG0077	Prephenate dehydratase
BsBEST3136_38870	COG2814	Major facilitator Superfamily
BsBEST3136_38880	COG0833	amino acid
BsBEST3136_38890	COG4187	Peptidase family M20/M25/M40
BsBEST3136_38900	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_38910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3136_38930	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3136_38940	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3136_38950	COG1091	dTDP-4-dehydrorhamnose reductase activity
BsBEST3136_38960	COG1088	dTDP-glucose 4,6-dehydratase activity
BsBEST3136_38970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BsBEST3136_38980	COG3980	spore coat polysaccharide biosynthesis protein
BsBEST3136_38990	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BsBEST3136_39000	COG2089	acid synthase
BsBEST3136_39010	COG0456	acetyltransferase
BsBEST3136_39020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3136_39030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3136_39040	COG0463	Glycosyl transferase, family 2
BsBEST3136_39060	COG2363	Small membrane protein
BsBEST3136_39070	COG2233	PERMEase
BsBEST3136_39090	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_39100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BsBEST3136_39110	COG1216	Glycosyl transferase, family 2
BsBEST3136_39140	COG1695	Transcriptional regulator
BsBEST3136_39150	COG0351	phosphomethylpyrimidine kinase
BsBEST3136_39170	COG1621	beta-fructofuranosidase activity
BsBEST3136_39180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3136_39180	COG1263	PTS System
BsBEST3136_39190	COG2116	formate transmembrane transporter activity
BsBEST3136_39200	COG3711	transcriptional antiterminator
BsBEST3136_39220	COG1404	Belongs to the peptidase S8 family
BsBEST3136_39230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3136_39240	COG0778	Nitroreductase
BsBEST3136_39250	COG0772	Belongs to the SEDS family
BsBEST3136_39270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3136_39280	COG1845	cytochrome c oxidase, subunit III
BsBEST3136_39290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3136_39300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3136_39310	COG2261	transglycosylase associated protein
BsBEST3136_39320	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BsBEST3136_39330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BsBEST3136_39340	COG2246	polysaccharide biosynthetic process
BsBEST3136_39350	COG1309	transcriptional regulator
BsBEST3136_39370	COG3162	membrane
BsBEST3136_39380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3136_39390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3136_39400	COG2837	iron assimilation
BsBEST3136_39410	COG2822	iron ion transport
BsBEST3136_39420	COG0672	)-iron permease
BsBEST3136_39430	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3136_39440	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BsBEST3136_39450	COG0583	DNA-binding transcription factor activity
BsBEST3136_39460	COG1380	Effector of murein hydrolase LrgA
BsBEST3136_39470	COG1346	cytolysis
BsBEST3136_39480	COG2814	Major facilitator Superfamily
BsBEST3136_39490	COG4895	conserved protein (DUF2196)
BsBEST3136_39500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BsBEST3136_39510	COG0346	lactoylglutathione lyase activity
BsBEST3136_39530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3136_39540	COG1404	Belongs to the peptidase S8 family
BsBEST3136_39550	COG1263	PTS System
BsBEST3136_39550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3136_39560	COG3711	transcriptional antiterminator
BsBEST3136_39570	COG1442	glycosyl transferase family 8
BsBEST3136_39580	COG5522	Integral membrane protein (intg_mem_TP0381)
BsBEST3136_39590	COG1846	Transcriptional regulator
BsBEST3136_39600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3136_39610	COG2234	aminopeptidase activity
BsBEST3136_39620	COG2357	RelA SpoT domain protein
BsBEST3136_39640	COG2801	Transposase and inactivated derivatives
BsBEST3136_39650	COG1575	Belongs to the MenA family. Type 1 subfamily
BsBEST3136_39660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3136_39670	COG1696	Membrane protein involved in D-alanine export
BsBEST3136_39680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3136_39690	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BsBEST3136_39700	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3136_39710	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3136_39720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3136_39730	COG1486	melibiose metabolic process
BsBEST3136_39740	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3136_39750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3136_39760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3136_39770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3136_39770	COG3711	transcriptional antiterminator
BsBEST3136_39790	COG2094	Belongs to the DNA glycosylase MPG family
BsBEST3136_39800	COG0753	catalase activity
BsBEST3136_39810	COG2814	Major facilitator Superfamily
BsBEST3136_39820	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3136_39830	COG1131	(ABC) transporter
BsBEST3136_39870	COG1595	DNA-templated transcription, initiation
BsBEST3136_39880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3136_39890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BsBEST3136_39900	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BsBEST3136_39910	COG4988	ABC transporter
BsBEST3136_39920	COG1294	oxidase, subunit
BsBEST3136_39930	COG1271	oxidase subunit
BsBEST3136_39940	COG3493	citrate carrier protein
BsBEST3136_39950	COG0501	Belongs to the peptidase M48B family
BsBEST3136_39970	COG0726	polysaccharide deacetylase
BsBEST3136_39980	COG3842	ATPase activity
BsBEST3136_39990	COG2508	Transcriptional regulator
BsBEST3136_40000	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_40010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3136_40020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BsBEST3136_40040	COG4585	Histidine kinase
BsBEST3136_40050	COG2197	response regulator
BsBEST3136_40060	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3136_40080	COG4894	glucomannan catabolic process
BsBEST3136_40090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3136_40100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3136_40110	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_40120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3136_40130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3136_40140	COG2610	gluconate transmembrane transporter activity
BsBEST3136_40150	COG0500	methyltransferase
BsBEST3136_40160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3136_40190	COG0753	catalase activity
BsBEST3136_40190	COG0693	protein deglycase activity
BsBEST3136_40200	COG2851	Citrate transporter
BsBEST3136_40210	COG2273	Hydrolase Family 16
BsBEST3136_40220	COG3711	transcriptional antiterminator
BsBEST3136_40240	COG2270	Major facilitator Superfamily
BsBEST3136_40250	COG0513	Belongs to the DEAD box helicase family
BsBEST3136_40260	COG2755	lipolytic protein G-D-S-L family
BsBEST3136_40260	COG3401	FG-GAP repeat protein
BsBEST3136_40500	COG0697	spore germination
BsBEST3136_40530	COG0589	response to stress
BsBEST3136_40540	COG2723	6-phospho-beta-galactosidase activity
BsBEST3136_40550	COG2723	6-phospho-beta-galactosidase activity
BsBEST3136_40560	COG2190	(PTS) system
BsBEST3136_40560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3136_40560	COG1263	PTS System
BsBEST3136_40590	COG5444	nuclease activity
BsBEST3136_40620	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3136_40650	COG2986	histidine ammonia-lyase
BsBEST3136_40660	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BsBEST3136_40670	COG1228	amidohydrolase
BsBEST3136_40680	COG0010	Belongs to the arginase family
BsBEST3136_40690	COG0833	amino acid
BsBEST3136_40700	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BsBEST3136_40710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3136_40720	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BsBEST3136_40730	COG2390	Transcriptional regulator
BsBEST3136_40750	COG3192	ethanolamine utilization protein
BsBEST3136_40760	COG2079	MmgE PrpD family protein
BsBEST3136_40770	COG1473	amidohydrolase
BsBEST3136_40780	COG1126	abc transporter atp-binding protein
BsBEST3136_40790	COG0765	amino acid transport
BsBEST3136_40800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3136_40810	COG0456	acetyltransferase
BsBEST3136_40820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3136_40840	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BsBEST3136_40850	COG0561	phosphatase activity
BsBEST3136_40910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3136_40920	COG5294	Protein conserved in bacteria
BsBEST3136_40930	COG0577	efflux transmembrane transporter activity
BsBEST3136_40940	COG0577	efflux transmembrane transporter activity
BsBEST3136_40950	COG1136	(ABC) transporter
BsBEST3136_40960	COG1136	(ABC) transporter
BsBEST3136_40970	COG2205	protein histidine kinase activity
BsBEST3136_40980	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_40990	COG0191	fructose-bisphosphate aldolase activity
BsBEST3136_41000	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3136_41010	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3136_41020	COG0673	inositol 2-dehydrogenase activity
BsBEST3136_41030	COG2814	Major facilitator Superfamily
BsBEST3136_41040	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3136_41050	COG3962	Belongs to the TPP enzyme family
BsBEST3136_41060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3136_41080	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_41090	COG1349	DNA-binding transcription factor activity
BsBEST3136_41100	COG0667	Aldo Keto reductase
BsBEST3136_41130	COG2814	Major facilitator Superfamily
BsBEST3136_41140	COG0326	Molecular chaperone. Has ATPase activity
BsBEST3136_41160	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_41170	COG1309	transcriptional regulator
BsBEST3136_41180	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3136_41190	COG0456	acetyltransferase
BsBEST3136_41200	COG2850	peptidyl-arginine hydroxylation
BsBEST3136_41210	COG2226	methyltransferase
BsBEST3136_41240	COG0367	asparagine synthase
BsBEST3136_41250	COG2814	Major facilitator Superfamily
BsBEST3136_41260	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BsBEST3136_41280	COG1714	RDD family
BsBEST3136_41290	COG2311	Membrane
BsBEST3136_41300	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3136_41310	COG1309	transcriptional regulator
BsBEST3136_41320	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3136_41330	COG1846	Transcriptional regulator
BsBEST3136_41340	COG1380	Effector of murein hydrolase LrgA
BsBEST3136_41350	COG1346	cytolysis
BsBEST3136_41360	COG5039	Polysaccharide pyruvyl transferase
BsBEST3136_41370	COG1929	Belongs to the glycerate kinase type-1 family
BsBEST3136_41380	COG1802	Transcriptional regulator
BsBEST3136_41390	COG1070	Carbohydrate kinase
BsBEST3136_41400	COG2610	gluconate transmembrane transporter activity
BsBEST3136_41410	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3136_41420	COG0450	alkyl hydroperoxide reductase
BsBEST3136_41430	COG3634	alkyl hydroperoxide reductase activity
BsBEST3136_41440	COG2723	6-phospho-beta-galactosidase activity
BsBEST3136_41450	COG2190	(PTS) system
BsBEST3136_41460	COG2188	Transcriptional regulator
BsBEST3136_41490	COG1131	(ABC) transporter
BsBEST3136_41500	COG1994	Peptidase M50
BsBEST3136_41510	COG0535	radical SAM domain protein
BsBEST3136_41540	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BsBEST3136_41550	COG5293	efflux transmembrane transporter activity
BsBEST3136_41570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3136_41580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BsBEST3136_41610	COG1063	alcohol dehydrogenase
BsBEST3136_41650	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BsBEST3136_41660	COG0456	acetyltransferase
BsBEST3136_41670	COG0457	Tetratricopeptide repeat
BsBEST3136_41680	COG0010	Belongs to the arginase family
BsBEST3136_41690	COG0833	amino acid
BsBEST3136_41700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3136_41710	COG3829	transcription factor binding
BsBEST3136_41720	COG5002	protein histidine kinase activity
BsBEST3136_41740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3136_41750	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BsBEST3136_41760	COG4853	Protein conserved in bacteria
BsBEST3136_41770	COG4863	YycH protein
BsBEST3136_41780	COG5002	protein histidine kinase activity
BsBEST3136_41790	COG0745	RESPONSE REGULATOR receiver
BsBEST3136_41810	COG0346	lactoylglutathione lyase activity
BsBEST3136_41820	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3136_41850	COG3093	addiction module antidote protein HigA
BsBEST3136_41860	COG2807	transmembrane transport
BsBEST3136_41870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3136_41880	COG0359	binds to the 23S rRNA
BsBEST3136_41890	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BsBEST3136_41900	COG4241	membrane
BsBEST3136_41920	COG5577	PFAM Coat F domain
BsBEST3136_41930	COG5577	PFAM Coat F domain
BsBEST3136_41940	COG1733	regulation of RNA biosynthetic process
BsBEST3136_41950	COG1227	inorganic diphosphatase activity
BsBEST3136_41980	COG2271	Major facilitator Superfamily
BsBEST3136_41990	COG0789	Transcriptional regulator
BsBEST3136_41990	COG4978	Transcriptional regulator
BsBEST3136_42010	COG4319	ketosteroid isomerase
BsBEST3136_42020	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3136_42030	COG2814	Major facilitator Superfamily
BsBEST3136_42040	COG0583	DNA-binding transcription factor activity
BsBEST3136_42050	COG2153	protein acetylation
BsBEST3136_42070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3136_42080	COG1846	Transcriptional regulator
BsBEST3136_42090	COG2153	protein acetylation
BsBEST3136_42100	COG2364	Membrane
BsBEST3136_42110	COG0456	acetyltransferase
BsBEST3136_42120	COG2315	Protein conserved in bacteria
BsBEST3136_42130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3136_42140	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3136_42150	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BsBEST3136_42160	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3136_42170	COG1266	CAAX protease self-immunity
BsBEST3136_42180	COG2814	Major facilitator Superfamily
BsBEST3136_42180	COG0477	Major facilitator Superfamily
BsBEST3136_42190	COG0346	lactoylglutathione lyase activity
BsBEST3136_42200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3136_42210	COG0542	response to heat
BsBEST3136_42230	COG1609	Transcriptional regulator
BsBEST3136_42240	COG0708	Exodeoxyribonuclease III
BsBEST3136_42250	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BsBEST3136_42260	COG0629	single-stranded DNA binding
BsBEST3136_42270	COG0360	Binds together with S18 to 16S ribosomal RNA
BsBEST3136_42280	COG0012	GTP binding
BsBEST3136_42290	COG0243	molybdopterin cofactor binding
BsBEST3136_42300	COG4481	Protein conserved in bacteria
BsBEST3136_42310	COG3949	Membrane
BsBEST3136_42330	COG1475	DNA binding
BsBEST3136_42340	COG1192	Involved in chromosome partitioning
BsBEST3136_42360	COG1475	DNA binding
BsBEST3136_42370	COG0357	Ribosomal RNA small subunit methyltransferase G
BsBEST3136_42380	COG0445	tRNA wobble uridine modification
BsBEST3136_42390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BsBEST3136_42400	COG1847	R3H domain protein
BsBEST3136_42410	COG0706	membrane insertase activity
BsBEST3136_42420	COG0594	ribonuclease P activity