locus-tag	class	description
BsBEST3145_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BsBEST3145_00020	COG0592	DNA-directed DNA polymerase activity
BsBEST3145_00030	COG2501	S4 domain
BsBEST3145_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BsBEST3145_00060	COG0187	DNA topoisomerase II activity
BsBEST3145_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3145_00090	COG0516	GMP reductase activity
BsBEST3145_00090	COG0517	IMP dehydrogenase activity
BsBEST3145_00100	COG1686	Belongs to the peptidase S11 family
BsBEST3145_00110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BsBEST3145_00120	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BsBEST3145_00130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BsBEST3145_00140	COG1428	Deoxynucleoside kinase
BsBEST3145_00150	COG1428	Deoxynucleoside kinase
BsBEST3145_00160	COG1388	LysM domain
BsBEST3145_00160	COG3858	chitin binding
BsBEST3145_00170	COG1335	isochorismatase
BsBEST3145_00180	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3145_00190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BsBEST3145_00200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BsBEST3145_00210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BsBEST3145_00250	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BsBEST3145_00260	COG3853	Toxic anion resistance protein (TelA)
BsBEST3145_00270	COG1982	Orn Lys Arg decarboxylase major
BsBEST3145_00280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3145_00290	COG3870	Protein conserved in bacteria
BsBEST3145_00300	COG1728	Protein conserved in bacteria
BsBEST3145_00310	COG0470	DNA polymerase III
BsBEST3145_00320	COG1774	PSP1 C-terminal conserved region
BsBEST3145_00330	COG4467	Involved in initiation control of chromosome replication
BsBEST3145_00340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BsBEST3145_00350	COG2827	Endonuclease containing a URI domain
BsBEST3145_00360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BsBEST3145_00370	COG2002	toxin-antitoxin pair type II binding
BsBEST3145_00380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3145_00380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3145_00390	COG0084	hydrolase, TatD family'
BsBEST3145_00400	COG3584	3D domain protein
BsBEST3145_00400	COG3583	domain protein
BsBEST3145_00410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3145_00420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BsBEST3145_00440	COG4466	Protein conserved in bacteria
BsBEST3145_00460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BsBEST3145_00470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3145_00480	COG0251	oxidation-reduction process
BsBEST3145_00490	COG2088	sporulation resulting in formation of a cellular spore
BsBEST3145_00500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BsBEST3145_00510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BsBEST3145_00520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BsBEST3145_00530	COG0193	aminoacyl-tRNA hydrolase activity
BsBEST3145_00550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BsBEST3145_00560	COG2002	toxin-antitoxin pair type II binding
BsBEST3145_00570	COG2244	polysaccharide biosynthetic process
BsBEST3145_00580	COG3956	TIGRFAM MazG family protein
BsBEST3145_00590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BsBEST3145_00620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BsBEST3145_00630	COG1098	S1 RNA binding domain
BsBEST3145_00640	COG2208	phosphoserine phosphatase activity
BsBEST3145_00650	COG2304	oxidoreductase activity
BsBEST3145_00660	COG0515	serine threonine protein kinase
BsBEST3145_00670	COG0037	tRNA processing
BsBEST3145_00680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BsBEST3145_00690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3145_00700	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BsBEST3145_00710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BsBEST3145_00720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3145_00730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3145_00740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3145_00750	COG0512	Glutamine amidotransferase of anthranilate synthase
BsBEST3145_00760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3145_00770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BsBEST3145_00780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BsBEST3145_00790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BsBEST3145_00800	COG1396	sequence-specific DNA binding
BsBEST3145_00810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3145_00820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BsBEST3145_00830	COG4463	regulation of RNA biosynthetic process
BsBEST3145_00840	COG3880	PFAM UvrB UvrC protein
BsBEST3145_00850	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BsBEST3145_00860	COG0542	response to heat
BsBEST3145_00870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BsBEST3145_00880	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BsBEST3145_00890	COG4956	integral membrane protein (PIN domain superfamily)
BsBEST3145_00900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BsBEST3145_00910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BsBEST3145_00920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BsBEST3145_00930	COG1045	serine acetyltransferase
BsBEST3145_00940	COG0215	cysteine-tRNA ligase activity
BsBEST3145_00950	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BsBEST3145_00960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3145_00970	COG3688	RNA-binding protein containing a PIN domain
BsBEST3145_00980	COG1595	DNA-templated transcription, initiation
BsBEST3145_00990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3145_01000	COG0250	Participates in transcription elongation, termination and antitermination
BsBEST3145_01020	COG0081	regulation of translation
BsBEST3145_01030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BsBEST3145_01050	COG2813	Specifically methylates the guanine in position
BsBEST3145_01060	COG0085	RNA polymerase activity
BsBEST3145_01070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BsBEST3145_01080	COG1358	cellular component organization or biogenesis
BsBEST3145_01090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BsBEST3145_01100	COG0049	tRNA binding
BsBEST3145_01110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BsBEST3145_01120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BsBEST3145_01130	COG0596	Alpha beta hydrolase
BsBEST3145_01150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BsBEST3145_01160	COG0088	Forms part of the polypeptide exit tunnel
BsBEST3145_01180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BsBEST3145_01210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BsBEST3145_01220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BsBEST3145_01240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BsBEST3145_01250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BsBEST3145_01270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BsBEST3145_01290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BsBEST3145_01300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BsBEST3145_01310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BsBEST3145_01340	COG0200	Binds to the 23S rRNA
BsBEST3145_01350	COG0201	protein transport
BsBEST3145_01360	COG0563	adenylate kinase activity
BsBEST3145_01370	COG0024	Methionine aminopeptidase
BsBEST3145_01380	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BsBEST3145_01400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BsBEST3145_01410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BsBEST3145_01420	COG0202	RNA polymerase activity
BsBEST3145_01430	COG0203	ribosomal protein L17
BsBEST3145_01440	COG1122	ATPase activity
BsBEST3145_01450	COG1122	ATPase activity
BsBEST3145_01460	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3145_01470	COG0101	tRNA pseudouridine synthase activity
BsBEST3145_01480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BsBEST3145_01490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BsBEST3145_01500	COG2226	methyltransferase
BsBEST3145_01520	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_01530	COG0489	protein tyrosine kinase activity
BsBEST3145_01550	COG2194	sulfuric ester hydrolase activity
BsBEST3145_01560	COG0726	polysaccharide deacetylase
BsBEST3145_01570	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3145_01590	COG0385	Bile acid
BsBEST3145_01600	COG2819	hydrolase of the alpha beta superfamily
BsBEST3145_01610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3145_01620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3145_01630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3145_01640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3145_01640	COG2207	Transcriptional regulator
BsBEST3145_01650	COG3876	Protein conserved in bacteria
BsBEST3145_01660	COG1472	Belongs to the glycosyl hydrolase 3 family
BsBEST3145_01670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3145_01680	COG1263	PTS System
BsBEST3145_01680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3145_01690	COG1737	Transcriptional regulator
BsBEST3145_01700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BsBEST3145_01710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3145_01720	COG1683	Conserved Protein
BsBEST3145_01730	COG1595	DNA-templated transcription, initiation
BsBEST3145_01740	COG5662	AntiSigma factor
BsBEST3145_01750	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3145_01760	COG4856	YbbR-like protein
BsBEST3145_01770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3145_01780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BsBEST3145_01800	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3145_01810	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3145_01820	COG2169	Transcriptional regulator
BsBEST3145_01830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3145_01840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3145_01860	COG3002	Belongs to the UPF0753 family
BsBEST3145_01870	COG0288	reversible hydration of carbon dioxide
BsBEST3145_01890	COG5609	conserved protein (DUF2294)
BsBEST3145_01900	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_01910	COG0642	Histidine kinase
BsBEST3145_01930	COG0515	serine threonine protein kinase
BsBEST3145_01960	COG1113	amino acid transport
BsBEST3145_01990	COG2602	Beta-lactamase
BsBEST3145_02000	COG2124	cytochrome p450
BsBEST3145_02020	COG0531	amino acid
BsBEST3145_02030	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3145_02040	COG2271	Major facilitator Superfamily
BsBEST3145_02060	COG0456	acetyltransferase
BsBEST3145_02060	COG1846	Transcriptional regulator
BsBEST3145_02070	COG2271	Major facilitator Superfamily
BsBEST3145_02080	COG2271	Major facilitator Superfamily
BsBEST3145_02110	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_02120	COG0697	spore germination
BsBEST3145_02130	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3145_02130	COG2207	Transcriptional regulator
BsBEST3145_02190	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BsBEST3145_02200	COG3591	Belongs to the peptidase S1B family
BsBEST3145_02220	COG0596	Alpha beta hydrolase
BsBEST3145_02230	COG1183	phosphatidylcholine synthase activity
BsBEST3145_02240	COG0586	Pfam SNARE associated Golgi protein
BsBEST3145_02250	COG0688	phosphatidylethanolamine metabolic process
BsBEST3145_02270	COG2312	Erythromycin esterase
BsBEST3145_02280	COG2207	Transcriptional regulator
BsBEST3145_02290	COG1054	Belongs to the UPF0176 family
BsBEST3145_02300	COG1301	dicarboxylic acid transport
BsBEST3145_02310	COG1263	PTS System
BsBEST3145_02310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3145_02310	COG2190	(PTS) system
BsBEST3145_02320	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3145_02330	COG2188	Transcriptional regulator
BsBEST3145_02350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3145_02360	COG0833	amino acid
BsBEST3145_02370	COG2040	homocysteine
BsBEST3145_02380	COG1115	amino acid carrier protein
BsBEST3145_02390	COG1115	amino acid carrier protein
BsBEST3145_02400	COG2066	Belongs to the glutaminase family
BsBEST3145_02410	COG4191	Histidine kinase
BsBEST3145_02420	COG0784	Response regulator, receiver
BsBEST3145_02430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3145_02440	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_02450	COG2271	Major facilitator Superfamily
BsBEST3145_02460	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3145_02470	COG2186	Transcriptional regulator
BsBEST3145_02480	COG2721	sulfolactate sulfo-lyase activity
BsBEST3145_02490	COG3173	Aminoglycoside phosphotransferase
BsBEST3145_02510	COG0697	spore germination
BsBEST3145_02520	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_02530	COG2205	protein histidine kinase activity
BsBEST3145_02540	COG1131	(ABC) transporter
BsBEST3145_02570	COG3773	Cell wall hydrolase
BsBEST3145_02580	COG2304	oxidoreductase activity
BsBEST3145_02590	COG3540	Alkaline phosphatase
BsBEST3145_02600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3145_02610	COG0805	protein transport
BsBEST3145_02620	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BsBEST3145_02630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3145_02640	COG0477	Major facilitator Superfamily
BsBEST3145_02650	COG1309	transcriptional regulator
BsBEST3145_02660	COG0252	asparaginase activity
BsBEST3145_02670	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3145_02680	COG1714	RDD family
BsBEST3145_02690	COG1405	negative regulation of cell septum assembly
BsBEST3145_02690	COG3012	SEC-C Motif Domain Protein
BsBEST3145_02700	COG3290	protein histidine kinase activity
BsBEST3145_02710	COG3279	Response regulator of the LytR AlgR family
BsBEST3145_02720	COG4555	ABC transporter
BsBEST3145_02730	COG4555	ABC transporter
BsBEST3145_02740	COG1668	transmembrane transport
BsBEST3145_02750	COG0667	Aldo Keto reductase
BsBEST3145_02770	COG1595	DNA-templated transcription, initiation
BsBEST3145_02780	COG1595	DNA-templated transcription, initiation
BsBEST3145_02790	COG1876	peptidase activity
BsBEST3145_02800	COG0457	Tetratricopeptide repeat
BsBEST3145_02810	COG0457	Tetratricopeptide repeat
BsBEST3145_02820	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_02830	COG0366	Alpha amylase catalytic
BsBEST3145_02840	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3145_02850	COG1121	(ABC) transporter
BsBEST3145_02860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3145_02870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_02880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_02890	COG2310	stress, protein
BsBEST3145_02900	COG2310	stress, protein
BsBEST3145_02910	COG2310	stress, protein
BsBEST3145_02920	COG0861	Integral membrane protein TerC family
BsBEST3145_02940	COG3853	Toxic anion resistance protein (TelA)
BsBEST3145_02950	COG0477	Major facilitator Superfamily
BsBEST3145_02960	COG2814	Major facilitator Superfamily
BsBEST3145_02970	COG0640	Transcriptional regulator
BsBEST3145_02980	COG0517	IMP dehydrogenase activity
BsBEST3145_02980	COG4175	Glycine betaine
BsBEST3145_02990	COG4176	ABC-type proline glycine betaine transport system permease component
BsBEST3145_03000	COG2113	Glycine betaine
BsBEST3145_03010	COG1473	amidohydrolase
BsBEST3145_03020	COG1288	antiporter activity
BsBEST3145_03040	COG0366	Alpha amylase catalytic
BsBEST3145_03050	COG0366	Alpha amylase catalytic
BsBEST3145_03060	COG0039	L-malate dehydrogenase activity
BsBEST3145_03070	COG1620	l-lactate permease
BsBEST3145_03080	COG1620	l-lactate permease
BsBEST3145_03090	COG3403	YqcI/YcgG family
BsBEST3145_03110	COG1113	amino acid transport
BsBEST3145_03120	COG1113	amino acid transport
BsBEST3145_03130	COG3665	Urea carboxylase-associated protein
BsBEST3145_03140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BsBEST3145_03150	COG1660	Displays ATPase and GTPase activities
BsBEST3145_03160	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BsBEST3145_03170	COG2801	Transposase and inactivated derivatives
BsBEST3145_03200	COG2226	methyltransferase
BsBEST3145_03210	COG0583	DNA-binding transcription factor activity
BsBEST3145_03220	COG3458	cephalosporin-C deacetylase activity
BsBEST3145_03230	COG3541	Predicted nucleotidyltransferase
BsBEST3145_03240	COG0506	proline dehydrogenase activity
BsBEST3145_03250	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_03260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3145_03270	COG2508	Transcriptional regulator
BsBEST3145_03280	COG3689	TIGRFAM TIGR03943 family protein
BsBEST3145_03290	COG0701	Predicted permease
BsBEST3145_03300	COG2267	carboxylic ester hydrolase activity
BsBEST3145_03310	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3145_03320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3145_03320	COG1587	Uroporphyrinogen-III synthase
BsBEST3145_03330	COG2146	nitrite reductase [NAD(P)H] activity
BsBEST3145_03340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3145_03350	COG0243	molybdopterin cofactor binding
BsBEST3145_03360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3145_03370	COG2223	nitrite transmembrane transporter activity
BsBEST3145_03380	COG1469	GTP cyclohydrolase I activity
BsBEST3145_03390	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3145_03410	COG0523	cobalamin synthesis protein
BsBEST3145_03420	COG0523	cobalamin synthesis protein
BsBEST3145_03430	COG0765	amino acid transport
BsBEST3145_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3145_03460	COG1714	RDD family
BsBEST3145_03480	COG1846	Transcriptional regulator
BsBEST3145_03520	COG2723	6-phospho-beta-galactosidase activity
BsBEST3145_03540	COG3209	COG3209 Rhs family protein
BsBEST3145_03550	COG0840	transmembrane signaling receptor activity
BsBEST3145_03550	COG3290	protein histidine kinase activity
BsBEST3145_03560	COG0840	transmembrane signaling receptor activity
BsBEST3145_03560	COG3290	protein histidine kinase activity
BsBEST3145_03570	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BsBEST3145_03580	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BsBEST3145_03590	COG1733	regulation of RNA biosynthetic process
BsBEST3145_03600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_03610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_03620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_03630	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BsBEST3145_03640	COG2814	Major facilitator Superfamily
BsBEST3145_03660	COG0697	spore germination
BsBEST3145_03670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3145_03690	COG2364	Membrane
BsBEST3145_03700	COG1126	abc transporter atp-binding protein
BsBEST3145_03710	COG0765	amino acid transport
BsBEST3145_03720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3145_03730	COG0583	DNA-binding transcription factor activity
BsBEST3145_03740	COG0163	prenyltransferase activity
BsBEST3145_03750	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BsBEST3145_03780	COG0596	Alpha beta hydrolase
BsBEST3145_03790	COG3104	oligopeptide transport
BsBEST3145_03800	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3145_03820	COG0697	spore germination
BsBEST3145_03840	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3145_03850	COG1136	(ABC) transporter
BsBEST3145_03860	COG0577	efflux transmembrane transporter activity
BsBEST3145_03870	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_03880	COG3850	Histidine kinase
BsBEST3145_03880	COG5002	protein histidine kinase activity
BsBEST3145_03890	COG0457	Tetratricopeptide repeat
BsBEST3145_03910	COG0527	aspartate kinase activity
BsBEST3145_03920	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3145_03930	COG4605	iron ion homeostasis
BsBEST3145_03940	COG4604	ABC transporter, ATP-binding protein
BsBEST3145_03950	COG4607	ABC-type enterochelin transport system periplasmic component
BsBEST3145_03960	COG2814	Major facilitator Superfamily
BsBEST3145_03970	COG1309	transcriptional regulator
BsBEST3145_03980	COG0778	Nitroreductase
BsBEST3145_03990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3145_04000	COG0640	Transcriptional regulator
BsBEST3145_04010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3145_04020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BsBEST3145_04030	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_04040	COG4975	Glucose uptake
BsBEST3145_04050	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_04060	COG4549	nuclear export factor GLE1
BsBEST3145_04070	COG1276	copper resistance
BsBEST3145_04070	COG2372	response to copper ion
BsBEST3145_04080	COG1349	DNA-binding transcription factor activity
BsBEST3145_04100	COG2213	PTS system mannitol-specific
BsBEST3145_04110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3145_04120	COG0246	Mannitol dehydrogenase
BsBEST3145_04130	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3145_04150	COG0681	Belongs to the peptidase S26 family
BsBEST3145_04160	COG0412	Dienelactone hydrolase
BsBEST3145_04170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3145_04190	COG0561	phosphatase activity
BsBEST3145_04200	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3145_04210	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3145_04220	COG4336	lyase activity
BsBEST3145_04230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BsBEST3145_04240	COG1984	allophanate hydrolase subunit 2
BsBEST3145_04250	COG1414	Transcriptional regulator
BsBEST3145_04260	COG2755	lipolytic protein G-D-S-L family
BsBEST3145_04280	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3145_04290	COG0768	penicillin binding
BsBEST3145_04300	COG4989	oxidoreductase activity
BsBEST3145_04310	COG3711	transcriptional antiterminator
BsBEST3145_04320	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3145_04330	COG2226	methyltransferase
BsBEST3145_04340	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_04350	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3145_04360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3145_04370	COG3871	stress protein (general stress protein 26)
BsBEST3145_04390	COG2814	Major facilitator Superfamily
BsBEST3145_04400	COG1522	sequence-specific DNA binding
BsBEST3145_04410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3145_04410	COG0551	DNA topoisomerase type I activity
BsBEST3145_04420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BsBEST3145_04430	COG3706	GGDEF domain
BsBEST3145_04440	COG5298	Protein conserved in bacteria
BsBEST3145_04450	COG1215	transferase activity, transferring glycosyl groups
BsBEST3145_04470	COG0531	amino acid
BsBEST3145_04480	COG0494	nUDIX hydrolase
BsBEST3145_04490	COG0028	Belongs to the TPP enzyme family
BsBEST3145_04520	COG1914	H( )-stimulated, divalent metal cation uptake system
BsBEST3145_04530	COG2261	transglycosylase associated protein
BsBEST3145_04540	COG4876	unkown
BsBEST3145_04550	COG2217	Heavy metal translocating P-type atpase
BsBEST3145_04560	COG3729	General stress protein
BsBEST3145_04570	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3145_04580	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3145_04590	COG3546	catalase activity
BsBEST3145_04600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BsBEST3145_04610	COG3290	protein histidine kinase activity
BsBEST3145_04620	COG4565	transcriptional regulatory protein
BsBEST3145_04630	COG1301	dicarboxylic acid transport
BsBEST3145_04640	COG0628	permease
BsBEST3145_04650	COG1131	(ABC) transporter
BsBEST3145_04660	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3145_04680	COG1960	acyl-CoA dehydrogenase activity
BsBEST3145_04710	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3145_04720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_04730	COG1181	Belongs to the D-alanine--D-alanine ligase family
BsBEST3145_04740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BsBEST3145_04750	COG0513	Belongs to the DEAD box helicase family
BsBEST3145_04760	COG3402	PFAM membrane-flanked domain
BsBEST3145_04770	COG3428	Bacterial PH domain
BsBEST3145_04780	COG0705	Rhomboid family
BsBEST3145_04790	COG0736	holo-[acyl-carrier-protein] synthase activity
BsBEST3145_04800	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BsBEST3145_04810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3145_04820	COG0864	Transcriptional regulator
BsBEST3145_04830	COG2337	Toxic component of a toxin-antitoxin (TA) module
BsBEST3145_04840	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3145_04850	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3145_04860	COG2172	sigma factor antagonist activity
BsBEST3145_04870	COG2208	phosphoserine phosphatase activity
BsBEST3145_04880	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3145_04890	COG2172	sigma factor antagonist activity
BsBEST3145_04900	COG1191	sigma factor activity
BsBEST3145_04910	COG2208	phosphoserine phosphatase activity
BsBEST3145_04940	COG1673	EVE domain
BsBEST3145_04950	COG1846	Transcriptional regulator
BsBEST3145_04960	COG2183	response to ionizing radiation
BsBEST3145_04970	COG3091	SprT-like family
BsBEST3145_04980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_04990	COG1522	sequence-specific DNA binding
BsBEST3145_05000	COG1522	sequence-specific DNA binding
BsBEST3145_05010	COG1335	isochorismatase
BsBEST3145_05020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3145_05030	COG2814	Major facilitator Superfamily
BsBEST3145_05070	COG0693	protein deglycase activity
BsBEST3145_05080	COG1278	Cold shock
BsBEST3145_05090	COG1329	Transcriptional regulator
BsBEST3145_05100	COG0697	spore germination
BsBEST3145_05110	COG2207	Transcriptional regulator
BsBEST3145_05110	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3145_05120	COG0697	spore germination
BsBEST3145_05130	COG3708	Transcriptional regulator
BsBEST3145_05130	COG2207	Transcriptional regulator
BsBEST3145_05140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3145_05150	COG0477	Major facilitator Superfamily
BsBEST3145_05170	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BsBEST3145_05190	COG0697	spore germination
BsBEST3145_05200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3145_05210	COG2030	dehydratase
BsBEST3145_05220	COG3545	Serine hydrolase
BsBEST3145_05230	COG1733	regulation of RNA biosynthetic process
BsBEST3145_05240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3145_05250	COG1733	regulation of RNA biosynthetic process
BsBEST3145_05260	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3145_05270	COG2814	Major facilitator Superfamily
BsBEST3145_05280	COG1309	transcriptional regulator
BsBEST3145_05300	COG0640	Transcriptional regulator
BsBEST3145_05310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3145_05320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3145_05330	COG0697	spore germination
BsBEST3145_05340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3145_05350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3145_05360	COG0640	Transcriptional regulator
BsBEST3145_05370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3145_05390	COG4585	Histidine kinase
BsBEST3145_05400	COG2197	response regulator
BsBEST3145_05410	COG2409	Drug exporters of the RND superfamily
BsBEST3145_05420	COG0596	Alpha beta hydrolase
BsBEST3145_05430	COG1811	Na channel or pump
BsBEST3145_05440	COG0789	Transcriptional regulator
BsBEST3145_05440	COG4978	Transcriptional regulator
BsBEST3145_05450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3145_05460	COG0778	Nitroreductase
BsBEST3145_05470	COG0346	lactoylglutathione lyase activity
BsBEST3145_05480	COG2259	Doxx family
BsBEST3145_05490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_05520	COG2323	membrane
BsBEST3145_05530	COG2323	membrane
BsBEST3145_05540	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3145_05570	COG1309	transcriptional regulator
BsBEST3145_05590	COG0456	acetyltransferase
BsBEST3145_05600	COG0488	(ABC) transporter
BsBEST3145_05610	COG1113	amino acid transport
BsBEST3145_05620	COG2318	DinB family
BsBEST3145_05630	COG1846	Transcriptional regulator
BsBEST3145_05640	COG1033	growth of symbiont in host cell
BsBEST3145_05640	COG2409	Drug exporters of the RND superfamily
BsBEST3145_05650	COG0778	Nitroreductase
BsBEST3145_05660	COG1846	Transcriptional regulator
BsBEST3145_05670	COG2814	Major facilitator Superfamily
BsBEST3145_05680	COG0730	response to heat
BsBEST3145_05690	COG1802	Transcriptional regulator
BsBEST3145_05700	COG3858	chitin binding
BsBEST3145_05700	COG1388	LysM domain
BsBEST3145_05710	COG1819	glycosyl
BsBEST3145_05730	COG1785	Belongs to the alkaline phosphatase family
BsBEST3145_05740	COG5646	InterPro IPR014922
BsBEST3145_05760	COG0454	-acetyltransferase
BsBEST3145_05770	COG1078	dGTPase activity
BsBEST3145_05780	COG1388	LysM domain
BsBEST3145_05790	COG2814	Major facilitator Superfamily
BsBEST3145_05800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3145_05810	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3145_05820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3145_05830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3145_05840	COG2723	6-phospho-beta-galactosidase activity
BsBEST3145_05850	COG2188	Transcriptional regulator
BsBEST3145_05860	COG1940	carbohydrate kinase activity
BsBEST3145_05870	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3145_05880	COG4124	Belongs to the glycosyl hydrolase 26 family
BsBEST3145_05910	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BsBEST3145_05920	COG0802	atpase or kinase
BsBEST3145_05930	COG1214	PFAM Peptidase M22, glycoprotease
BsBEST3145_05940	COG0456	acetyltransferase
BsBEST3145_05950	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BsBEST3145_05960	COG0488	(ABC) transporter
BsBEST3145_05970	COG0315	cyclic pyranopterin monophosphate synthase activity
BsBEST3145_05980	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BsBEST3145_05990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3145_06000	COG0805	protein transport
BsBEST3145_06020	COG1266	CAAX protease self-immunity
BsBEST3145_06040	COG0459	protein refolding
BsBEST3145_06070	COG3378	Phage plasmid primase P4 family
BsBEST3145_06100	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3145_06110	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3145_06140	COG1401	restriction endodeoxyribonuclease activity
BsBEST3145_06190	COG1073	alpha beta
BsBEST3145_06200	COG0457	Tetratricopeptide repeat
BsBEST3145_06210	COG1063	alcohol dehydrogenase
BsBEST3145_06220	COG2211	Major facilitator Superfamily
BsBEST3145_06230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3145_06240	COG1842	Phage shock protein A
BsBEST3145_06250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3145_06260	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BsBEST3145_06270	COG4260	virion core protein, lumpy skin disease virus
BsBEST3145_06290	COG2814	Major facilitator Superfamily
BsBEST3145_06300	COG1063	alcohol dehydrogenase
BsBEST3145_06310	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BsBEST3145_06320	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3145_06350	COG2267	carboxylic ester hydrolase activity
BsBEST3145_06370	COG2132	Multicopper oxidase
BsBEST3145_06380	COG1113	amino acid transport
BsBEST3145_06390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BsBEST3145_06400	COG0714	Associated with various cellular activities
BsBEST3145_06410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BsBEST3145_06420	COG1305	Transglutaminase-like
BsBEST3145_06430	COG0519	Catalyzes the synthesis of GMP from XMP
BsBEST3145_06430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BsBEST3145_06440	COG2252	PERMEase
BsBEST3145_06450	COG3064	Membrane
BsBEST3145_06470	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BsBEST3145_06490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BsBEST3145_06500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BsBEST3145_06510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BsBEST3145_06520	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BsBEST3145_06530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3145_06540	COG0047	phosphoribosylformylglycinamidine synthase activity
BsBEST3145_06550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BsBEST3145_06560	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BsBEST3145_06570	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BsBEST3145_06580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BsBEST3145_06590	COG0138	bifunctional purine biosynthesis protein purh
BsBEST3145_06600	COG0151	Belongs to the GarS family
BsBEST3145_06610	COG1522	sequence-specific DNA binding
BsBEST3145_06620	COG0531	amino acid
BsBEST3145_06630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3145_06640	COG1470	cell adhesion involved in biofilm formation
BsBEST3145_06650	COG4496	protein, YerC YecD
BsBEST3145_06660	COG0069	glutamate synthase activity
BsBEST3145_06670	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BsBEST3145_06680	COG0210	DNA helicase
BsBEST3145_06690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BsBEST3145_06700	COG4851	CamS sex pheromone cAM373 precursor
BsBEST3145_06720	COG2801	Transposase and inactivated derivatives
BsBEST3145_06730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3145_06740	COG1285	pathogenesis
BsBEST3145_06750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3145_06760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3145_06770	COG0154	amidase activity
BsBEST3145_06780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BsBEST3145_06790	COG1309	transcriptional regulator
BsBEST3145_06800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BsBEST3145_06810	COG1597	lipid kinase activity
BsBEST3145_06820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3145_06870	COG5444	nuclease activity
BsBEST3145_06880	COG3391	amine dehydrogenase activity
BsBEST3145_06890	COG3391	amine dehydrogenase activity
BsBEST3145_06900	COG0457	Tetratricopeptide repeat
BsBEST3145_06920	COG0217	transcriptional regulatory protein
BsBEST3145_06940	COG1309	transcriptional regulator
BsBEST3145_06980	COG3546	catalase activity
BsBEST3145_06990	COG0454	-acetyltransferase
BsBEST3145_07000	COG5578	integral membrane protein
BsBEST3145_07010	COG2972	Histidine kinase
BsBEST3145_07020	COG2207	Transcriptional regulator
BsBEST3145_07020	COG4753	response regulator
BsBEST3145_07030	COG4753	response regulator
BsBEST3145_07030	COG2207	Transcriptional regulator
BsBEST3145_07040	COG1653	transport
BsBEST3145_07050	COG1175	transmembrane transport
BsBEST3145_07060	COG0395	ABC-type sugar transport system, permease component
BsBEST3145_07070	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3145_07080	COG2207	Transcriptional regulator
BsBEST3145_07090	COG2755	lipolytic protein G-D-S-L family
BsBEST3145_07110	COG5578	integral membrane protein
BsBEST3145_07120	COG3401	FG-GAP repeat protein
BsBEST3145_07130	COG3401	FG-GAP repeat protein
BsBEST3145_07140	COG2755	lipolytic protein G-D-S-L family
BsBEST3145_07150	COG1874	Beta-galactosidase
BsBEST3145_07160	COG1874	Beta-galactosidase
BsBEST3145_07170	COG1874	Beta-galactosidase
BsBEST3145_07210	COG1653	transport
BsBEST3145_07220	COG4209	transmembrane transport
BsBEST3145_07230	COG0395	ABC-type sugar transport system, permease component
BsBEST3145_07240	COG1486	melibiose metabolic process
BsBEST3145_07250	COG2323	membrane
BsBEST3145_07260	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3145_07270	COG0346	lactoylglutathione lyase activity
BsBEST3145_07300	COG5583	Uncharacterized small protein (DUF2292)
BsBEST3145_07310	COG0670	Belongs to the BI1 family
BsBEST3145_07320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3145_07340	COG3328	transposase activity
BsBEST3145_07360	COG2124	cytochrome p450
BsBEST3145_07360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3145_07370	COG1368	sulfuric ester hydrolase activity
BsBEST3145_07380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BsBEST3145_07390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3145_07400	COG1442	glycosyl transferase family 8
BsBEST3145_07410	COG1216	Glycosyl transferase, family 2
BsBEST3145_07420	COG1442	glycosyl transferase family 8
BsBEST3145_07430	COG2223	nitrite transmembrane transporter activity
BsBEST3145_07440	COG1011	Hydrolase
BsBEST3145_07450	COG0531	amino acid
BsBEST3145_07460	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_07470	COG0840	transmembrane signaling receptor activity
BsBEST3145_07480	COG0488	(ABC) transporter
BsBEST3145_07500	COG0789	Transcriptional regulator
BsBEST3145_07510	COG2814	Major facilitator Superfamily
BsBEST3145_07530	COG0488	(ABC) transporter
BsBEST3145_07540	COG0513	Belongs to the DEAD box helicase family
BsBEST3145_07550	COG0456	acetyltransferase
BsBEST3145_07560	COG2130	NADP-dependent
BsBEST3145_07580	COG2211	Major facilitator Superfamily
BsBEST3145_07590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BsBEST3145_07600	COG1120	ATPase activity
BsBEST3145_07610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3145_07620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3145_07630	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3145_07660	COG3866	Pectate lyase
BsBEST3145_07670	COG0471	metal ion transport
BsBEST3145_07680	COG3290	protein histidine kinase activity
BsBEST3145_07690	COG4565	transcriptional regulatory protein
BsBEST3145_07700	COG3181	Tripartite tricarboxylate transporter family receptor
BsBEST3145_07710	COG2851	Citrate transporter
BsBEST3145_07720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3145_07730	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BsBEST3145_07740	COG1254	Belongs to the acylphosphatase family
BsBEST3145_07750	COG2258	MOSC domain
BsBEST3145_07790	COG0024	Methionine aminopeptidase
BsBEST3145_07800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3145_07800	COG1263	PTS System
BsBEST3145_07810	COG1368	sulfuric ester hydrolase activity
BsBEST3145_07830	COG1115	amino acid carrier protein
BsBEST3145_07840	COG0531	amino acid
BsBEST3145_07870	COG0697	spore germination
BsBEST3145_07880	COG1263	PTS System
BsBEST3145_07880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3145_07890	COG0366	Alpha amylase catalytic
BsBEST3145_07900	COG2188	Transcriptional regulator
BsBEST3145_07910	COG0778	Nitroreductase
BsBEST3145_07920	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3145_07930	COG0693	protein deglycase activity
BsBEST3145_07940	COG2814	Major facilitator Superfamily
BsBEST3145_07950	COG4840	Belongs to the UPF0435 family
BsBEST3145_07960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3145_07970	COG4980	gas vesicle protein
BsBEST3145_07980	COG1295	ribonuclease BN
BsBEST3145_07990	COG0477	Major facilitator Superfamily
BsBEST3145_08000	COG0387	Pfam Sodium calcium exchanger
BsBEST3145_08020	COG0668	transmembrane transport
BsBEST3145_08030	COG0535	radical SAM domain protein
BsBEST3145_08050	COG0726	polysaccharide deacetylase
BsBEST3145_08060	COG2084	Dehydrogenase
BsBEST3145_08070	COG0598	Magnesium transport protein CorA
BsBEST3145_08080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BsBEST3145_08090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BsBEST3145_08110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BsBEST3145_08120	COG4637	Psort location Cytoplasmic, score
BsBEST3145_08140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3145_08150	COG0022	dehydrogenase e1 component
BsBEST3145_08160	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3145_08170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3145_08180	COG3284	Transcriptional regulator
BsBEST3145_08200	COG1742	UPF0060 membrane protein
BsBEST3145_08250	COG4842	Belongs to the WXG100 family
BsBEST3145_08260	COG1486	melibiose metabolic process
BsBEST3145_08270	COG1737	Transcriptional regulator
BsBEST3145_08280	COG1263	PTS System
BsBEST3145_08280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3145_08290	COG1132	(ABC) transporter
BsBEST3145_08300	COG1132	(ABC) transporter
BsBEST3145_08310	COG2259	Doxx family
BsBEST3145_08320	COG2514	catechol 2,3-dioxygenase activity
BsBEST3145_08330	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3145_08330	COG4977	sequence-specific DNA binding
BsBEST3145_08340	COG2814	Major facilitator Superfamily
BsBEST3145_08350	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3145_08360	COG0673	inositol 2-dehydrogenase activity
BsBEST3145_08370	COG4585	Histidine kinase
BsBEST3145_08380	COG2197	response regulator
BsBEST3145_08390	COG1131	(ABC) transporter
BsBEST3145_08400	COG0842	Transport permease protein
BsBEST3145_08400	COG1511	domain protein
BsBEST3145_08410	COG0842	Transport permease protein
BsBEST3145_08420	COG1695	Transcriptional regulator
BsBEST3145_08430	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BsBEST3145_08440	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BsBEST3145_08450	COG1309	transcriptional regulator
BsBEST3145_08460	COG2814	Major facilitator Superfamily
BsBEST3145_08470	COG2318	DinB family
BsBEST3145_08480	COG2814	Major facilitator Superfamily
BsBEST3145_08490	COG1846	Transcriptional regulator
BsBEST3145_08500	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BsBEST3145_08500	COG0392	lysyltransferase activity
BsBEST3145_08510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3145_08520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3145_08530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3145_08540	COG0384	phenazine biosynthesis protein PhzF
BsBEST3145_08550	COG0778	Nitroreductase
BsBEST3145_08570	COG1090	epimerase
BsBEST3145_08580	COG2137	regulation of response to DNA damage stimulus
BsBEST3145_08600	COG2814	Major facilitator Superfamily
BsBEST3145_08630	COG3103	Sh3 type 3 domain protein
BsBEST3145_08640	COG5658	integral membrane protein
BsBEST3145_08650	COG0596	Alpha beta hydrolase
BsBEST3145_08660	COG0463	Glycosyl transferase, family 2
BsBEST3145_08670	COG4485	Bacterial membrane protein, YfhO
BsBEST3145_08680	COG1988	membrane-bound metal-dependent
BsBEST3145_08690	COG1194	a g-specific adenine glycosylase
BsBEST3145_08710	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_08740	COG3557	Belongs to the UPF0374 family
BsBEST3145_08750	COG1132	(ABC) transporter
BsBEST3145_08760	COG4129	membrane
BsBEST3145_08770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3145_08780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BsBEST3145_08790	COG0735	belongs to the Fur family
BsBEST3145_08820	COG4326	sporulation control protein
BsBEST3145_08840	COG3340	Belongs to the peptidase S51 family
BsBEST3145_08850	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BsBEST3145_08860	COG0277	FAD linked oxidase domain protein
BsBEST3145_08880	COG0753	catalase activity
BsBEST3145_08890	COG1116	anion transmembrane transporter activity
BsBEST3145_08900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3145_08910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3145_08920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_08940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BsBEST3145_08960	COG1476	TRANSCRIPTIONal
BsBEST3145_08970	COG3382	B3 4 domain protein
BsBEST3145_08980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BsBEST3145_09000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BsBEST3145_09010	COG0789	Transcriptional regulator
BsBEST3145_09020	COG1664	Polymer-forming cytoskeletal
BsBEST3145_09030	COG1664	Polymer-forming cytoskeletal
BsBEST3145_09040	COG2766	serine protein kinase
BsBEST3145_09050	COG2718	Belongs to the UPF0229 family
BsBEST3145_09060	COG1846	Transcriptional regulator
BsBEST3145_09070	COG1566	PFAM secretion protein HlyD family protein
BsBEST3145_09080	COG2814	Major facilitator Superfamily
BsBEST3145_09090	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3145_09120	COG1725	Transcriptional regulator
BsBEST3145_09130	COG1131	(ABC) transporter
BsBEST3145_09140	COG1131	(ABC) transporter
BsBEST3145_09150	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3145_09160	COG1278	Cold shock
BsBEST3145_09170	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3145_09180	COG3706	GGDEF domain
BsBEST3145_09190	COG1823	symporter activity
BsBEST3145_09230	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3145_09230	COG1525	nuclease
BsBEST3145_09230	COG4085	toxin activity
BsBEST3145_09240	COG3764	Sortase (surface protein transpeptidase)
BsBEST3145_09250	COG0564	pseudouridine synthase activity
BsBEST3145_09270	COG0517	IMP dehydrogenase activity
BsBEST3145_09280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3145_09290	COG3153	acetyltransferase
BsBEST3145_09290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3145_09310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3145_09320	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BsBEST3145_09330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BsBEST3145_09340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BsBEST3145_09350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BsBEST3145_09360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BsBEST3145_09370	COG2203	Gaf domain
BsBEST3145_09370	COG4585	Histidine kinase
BsBEST3145_09380	COG2197	response regulator
BsBEST3145_09390	COG0431	NADPH-dependent FMN reductase
BsBEST3145_09420	COG0791	NLP P60 protein
BsBEST3145_09420	COG1388	LysM domain
BsBEST3145_09430	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3145_09440	COG0668	transmembrane transport
BsBEST3145_09450	COG2719	SpoVR family
BsBEST3145_09460	COG1785	Belongs to the alkaline phosphatase family
BsBEST3145_09470	COG0791	NLP P60 protein
BsBEST3145_09470	COG1388	LysM domain
BsBEST3145_09480	COG0583	DNA-binding transcription factor activity
BsBEST3145_09490	COG0372	Belongs to the citrate synthase family
BsBEST3145_09500	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_09510	COG0531	amino acid
BsBEST3145_09520	COG0733	neurotransmitter:sodium symporter activity
BsBEST3145_09530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3145_09540	COG0456	acetyltransferase
BsBEST3145_09570	COG1595	DNA-templated transcription, initiation
BsBEST3145_09580	COG0667	Aldo Keto reductase
BsBEST3145_09590	COG0204	Acyl-transferase
BsBEST3145_09600	COG1253	flavin adenine dinucleotide binding
BsBEST3145_09610	COG0789	Transcriptional regulator
BsBEST3145_09620	COG0436	Aminotransferase
BsBEST3145_09630	COG0436	Aminotransferase
BsBEST3145_09640	COG1253	flavin adenine dinucleotide binding
BsBEST3145_09650	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3145_09660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BsBEST3145_09670	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3145_09690	COG0668	transmembrane transport
BsBEST3145_09700	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BsBEST3145_09710	COG0726	polysaccharide deacetylase
BsBEST3145_09720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3145_09730	COG1757	Na H antiporter
BsBEST3145_09740	COG0589	response to stress
BsBEST3145_09750	COG1132	(ABC) transporter
BsBEST3145_09760	COG1132	(ABC) transporter
BsBEST3145_09770	COG0702	epimerase
BsBEST3145_09810	COG0189	ligase activity
BsBEST3145_09820	COG0189	ligase activity
BsBEST3145_09830	COG4399	Belongs to the UPF0754 family
BsBEST3145_09840	COG3679	Belongs to the UPF0342 family
BsBEST3145_09850	COG4335	DNA alkylation repair
BsBEST3145_09860	COG4335	DNA alkylation repair
BsBEST3145_09870	COG0561	phosphatase activity
BsBEST3145_09880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3145_09890	COG0475	glutathione-regulated potassium exporter activity
BsBEST3145_09900	COG0490	domain, Protein
BsBEST3145_09920	COG1024	Enoyl-CoA hydratase
BsBEST3145_09940	COG4152	abc transporter atp-binding protein
BsBEST3145_09950	COG1668	transmembrane transport
BsBEST3145_09960	COG0420	3'-5' exonuclease activity
BsBEST3145_09970	COG4717	serine-type aminopeptidase activity
BsBEST3145_09980	COG3481	metal-dependent phosphohydrolase, HD sub domain
BsBEST3145_10000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BsBEST3145_10030	COG1846	Transcriptional regulator
BsBEST3145_10040	COG4980	gas vesicle protein
BsBEST3145_10060	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BsBEST3145_10070	COG0537	adenosine 5'-monophosphoramidase activity
BsBEST3145_10080	COG1131	(ABC) transporter
BsBEST3145_10090	COG4473	ABC transporter
BsBEST3145_10110	COG1473	amidohydrolase
BsBEST3145_10120	COG3069	C4-dicarboxylate transmembrane transporter activity
BsBEST3145_10140	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3145_10150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3145_10160	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BsBEST3145_10170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BsBEST3145_10180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BsBEST3145_10190	COG1309	transcriptional regulator
BsBEST3145_10200	COG1511	domain protein
BsBEST3145_10210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3145_10220	COG4377	Putative membrane peptidase family (DUF2324)
BsBEST3145_10240	COG1363	Peptidase, m42
BsBEST3145_10250	COG4405	Protein conserved in bacteria
BsBEST3145_10260	COG1301	dicarboxylic acid transport
BsBEST3145_10270	COG1234	tRNA 3'-trailer cleavage
BsBEST3145_10280	COG0095	Lipoate-protein ligase
BsBEST3145_10290	COG0702	epimerase
BsBEST3145_10300	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3145_10320	COG0501	Belongs to the peptidase M48B family
BsBEST3145_10340	COG0456	acetyltransferase
BsBEST3145_10350	COG0604	alcohol dehydrogenase
BsBEST3145_10360	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BsBEST3145_10370	COG0406	alpha-ribazole phosphatase activity
BsBEST3145_10380	COG0183	Belongs to the thiolase family
BsBEST3145_10390	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3145_10400	COG1268	BioY protein
BsBEST3145_10410	COG0840	transmembrane signaling receptor activity
BsBEST3145_10420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3145_10420	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3145_10430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3145_10430	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3145_10440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3145_10440	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3145_10450	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_10470	COG4903	ComK protein
BsBEST3145_10480	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_10500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3145_10530	COG0398	Pfam SNARE associated Golgi protein
BsBEST3145_10540	COG0681	Belongs to the peptidase S26 family
BsBEST3145_10550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BsBEST3145_10560	COG1846	Transcriptional regulator
BsBEST3145_10590	COG0738	Major facilitator superfamily
BsBEST3145_10620	COG0673	inositol 2-dehydrogenase activity
BsBEST3145_10630	COG0561	phosphatase activity
BsBEST3145_10640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3145_10650	COG1609	Transcriptional regulator
BsBEST3145_10660	COG3180	Ammonia monooxygenase
BsBEST3145_10670	COG2814	Major facilitator Superfamily
BsBEST3145_10670	COG0477	Major facilitator Superfamily
BsBEST3145_10680	COG4533	DNA binding
BsBEST3145_10710	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BsBEST3145_10720	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BsBEST3145_10730	COG1074	ATP-dependent DNA helicase activity
BsBEST3145_10740	COG0420	3'-5' exonuclease activity
BsBEST3145_10750	COG0419	ATPase involved in DNA repair
BsBEST3145_10760	COG1403	HNH endonuclease
BsBEST3145_10840	COG0179	Fumarylacetoacetate (FAA) hydrolase
BsBEST3145_10860	COG1404	Belongs to the peptidase S8 family
BsBEST3145_10880	COG0367	asparagine synthase
BsBEST3145_10890	COG1562	ergosterol biosynthetic process
BsBEST3145_10900	COG0534	Mate efflux family protein
BsBEST3145_10910	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3145_10910	COG2207	Transcriptional regulator
BsBEST3145_10920	COG1609	Transcriptional regulator
BsBEST3145_10930	COG0673	inositol 2-dehydrogenase activity
BsBEST3145_10940	COG2318	DinB family
BsBEST3145_10950	COG1279	arginine transmembrane transporter activity
BsBEST3145_10960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BsBEST3145_10970	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3145_10980	COG2267	carboxylic ester hydrolase activity
BsBEST3145_10990	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3145_11000	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3145_11010	COG0175	sulfate reduction
BsBEST3145_11020	COG2045	Belongs to the ComB family
BsBEST3145_11030	COG1809	phosphosulfolactate synthase activity
BsBEST3145_11040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3145_11050	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3145_11060	COG2814	Major facilitator Superfamily
BsBEST3145_11070	COG0454	-acetyltransferase
BsBEST3145_11080	COG2153	protein acetylation
BsBEST3145_11090	COG0646	methionine synthase
BsBEST3145_11090	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BsBEST3145_11100	COG1666	GTP binding
BsBEST3145_11110	COG2996	Protein conserved in bacteria
BsBEST3145_11150	COG1695	Transcriptional regulator
BsBEST3145_11180	COG3227	Zinc metalloprotease (Elastase)
BsBEST3145_11190	COG1307	EDD domain protein, DegV family
BsBEST3145_11200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3145_11230	COG0561	phosphatase activity
BsBEST3145_11240	COG1073	alpha beta
BsBEST3145_11250	COG2151	metal-sulfur cluster biosynthetic enzyme
BsBEST3145_11270	COG0277	FAD linked oxidase domain protein
BsBEST3145_11280	COG2271	Major facilitator Superfamily
BsBEST3145_11290	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BsBEST3145_11300	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BsBEST3145_11320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3145_11330	COG0505	Belongs to the CarA family
BsBEST3145_11340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3145_11350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BsBEST3145_11380	COG2267	carboxylic ester hydrolase activity
BsBEST3145_11400	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3145_11430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3145_11440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3145_11450	COG5504	Zn-dependent protease
BsBEST3145_11460	COG0444	Belongs to the ABC transporter superfamily
BsBEST3145_11470	COG4608	Belongs to the ABC transporter superfamily
BsBEST3145_11490	COG0601	transmembrane transport
BsBEST3145_11500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3145_11520	COG0180	Tryptophanyl-tRNA synthetase
BsBEST3145_11530	COG4166	transmembrane transport
BsBEST3145_11540	COG0601	transmembrane transport
BsBEST3145_11550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3145_11560	COG0444	Belongs to the ABC transporter superfamily
BsBEST3145_11570	COG4608	Belongs to the ABC transporter superfamily
BsBEST3145_11580	COG2814	Major facilitator Superfamily
BsBEST3145_11590	COG0456	acetyltransferase
BsBEST3145_11600	COG1393	Belongs to the ArsC family
BsBEST3145_11610	COG0861	Integral membrane protein TerC family
BsBEST3145_11620	COG4862	establishment of competence for transformation
BsBEST3145_11630	COG4469	Competence protein
BsBEST3145_11640	COG1164	Oligoendopeptidase f
BsBEST3145_11660	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3145_11670	COG2346	COG2346, Truncated hemoglobins
BsBEST3145_11680	COG0741	lytic transglycosylase activity
BsBEST3145_11690	COG4116	CYTH
BsBEST3145_11710	COG2357	RelA SpoT domain protein
BsBEST3145_11720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3145_11730	COG0564	pseudouridine synthase activity
BsBEST3145_11740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BsBEST3145_11750	COG0475	glutathione-regulated potassium exporter activity
BsBEST3145_11750	COG0569	domain protein
BsBEST3145_11760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BsBEST3145_11770	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3145_11780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3145_11790	COG2104	thiamine diphosphate biosynthetic process
BsBEST3145_11800	COG2022	thiamine diphosphate biosynthetic process
BsBEST3145_11810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3145_11820	COG0351	phosphomethylpyrimidine kinase
BsBEST3145_11830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BsBEST3145_11940	COG0210	DNA helicase
BsBEST3145_11960	COG2153	protein acetylation
BsBEST3145_11970	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3145_11980	COG2382	esterase
BsBEST3145_11990	COG0626	cystathionine gamma-synthase activity
BsBEST3145_12000	COG0626	cystathionine gamma-synthase activity
BsBEST3145_12010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3145_12020	COG5505	Protein of unknown function (DUF819)
BsBEST3145_12080	COG3677	Transposase
BsBEST3145_12110	COG5484	DNA packaging
BsBEST3145_12120	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BsBEST3145_12130	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_12150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3145_12150	COG3711	transcriptional antiterminator
BsBEST3145_12160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3145_12160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3145_12160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3145_12170	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3145_12190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3145_12210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3145_12250	COG0109	protoheme IX farnesyltransferase activity
BsBEST3145_12270	COG0726	polysaccharide deacetylase
BsBEST3145_12300	COG5504	Zn-dependent protease
BsBEST3145_12310	COG2205	protein histidine kinase activity
BsBEST3145_12330	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3145_12340	COG2427	Protein of unknown function (DUF1641)
BsBEST3145_12360	COG1051	belongs to the nudix hydrolase family
BsBEST3145_12380	COG2124	cytochrome p450
BsBEST3145_12390	COG1819	glycosyl
BsBEST3145_12410	COG1587	Uroporphyrinogen-III synthase
BsBEST3145_12420	COG0390	transport system, permease component
BsBEST3145_12430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3145_12440	COG0697	spore germination
BsBEST3145_12450	COG4297	protein containing double-stranded beta helix domain
BsBEST3145_12470	COG1252	NADH dehydrogenase
BsBEST3145_12480	COG1904	glucuronate isomerase
BsBEST3145_12490	COG2211	Major facilitator Superfamily
BsBEST3145_12500	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BsBEST3145_12510	COG1063	alcohol dehydrogenase
BsBEST3145_12520	COG1312	Catalyzes the dehydration of D-mannonate
BsBEST3145_12530	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_12540	COG2271	Major facilitator Superfamily
BsBEST3145_12550	COG1609	Transcriptional regulator
BsBEST3145_12560	COG0246	Mannitol dehydrogenase
BsBEST3145_12570	COG2721	sulfolactate sulfo-lyase activity
BsBEST3145_12580	COG0730	response to heat
BsBEST3145_12590	COG2318	DinB family
BsBEST3145_12600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BsBEST3145_12610	COG0457	Tetratricopeptide repeat
BsBEST3145_12630	COG2350	Protein conserved in bacteria
BsBEST3145_12640	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_12640	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_12640	COG1388	LysM domain
BsBEST3145_12660	COG4195	phage-related replication protein
BsBEST3145_12670	COG3546	catalase activity
BsBEST3145_12680	COG2856	Zn peptidase
BsBEST3145_12690	COG1396	sequence-specific DNA binding
BsBEST3145_12710	COG1522	sequence-specific DNA binding
BsBEST3145_12720	COG1484	DNA-dependent DNA replication
BsBEST3145_12760	COG1595	DNA-templated transcription, initiation
BsBEST3145_12770	COG5484	DNA packaging
BsBEST3145_12770	COG3728	DNA packaging
BsBEST3145_12780	COG1783	phage Terminase large subunit
BsBEST3145_12790	COG5518	Phage portal protein
BsBEST3145_12800	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3145_12810	COG4653	Phage capsid family
BsBEST3145_12910	COG3953	SLT domain
BsBEST3145_12910	COG5412	phage tail tape measure protein
BsBEST3145_12920	COG1652	LysM domain
BsBEST3145_12930	COG4193	domain, Protein
BsBEST3145_12950	COG3628	GPW Gp25 family protein
BsBEST3145_12960	COG3299	homolog of phage Mu protein gp47
BsBEST3145_12970	COG3778	Protein conserved in bacteria
BsBEST3145_13050	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_13050	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_13080	COG0306	phosphate transporter
BsBEST3145_13090	COG1392	Phosphate transport regulator
BsBEST3145_13100	COG0531	amino acid
BsBEST3145_13110	COG0346	lactoylglutathione lyase activity
BsBEST3145_13130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3145_13140	COG0463	Glycosyl transferase, family 2
BsBEST3145_13160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3145_13170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3145_13180	COG2362	D-Aminopeptidase
BsBEST3145_13190	COG0601	transmembrane transport
BsBEST3145_13200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BsBEST3145_13210	COG0444	Belongs to the ABC transporter superfamily
BsBEST3145_13220	COG4166	transmembrane transport
BsBEST3145_13230	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3145_13240	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3145_13250	COG0791	NLP P60 protein
BsBEST3145_13260	COG4608	Belongs to the ABC transporter superfamily
BsBEST3145_13270	COG2706	6-phosphogluconolactonase activity
BsBEST3145_13280	COG1834	amidinotransferase
BsBEST3145_13290	COG1607	acyl-coa hydrolase
BsBEST3145_13300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BsBEST3145_13300	COG1017	nitric oxide dioxygenase activity
BsBEST3145_13320	COG2323	membrane
BsBEST3145_13330	COG2318	DinB family
BsBEST3145_13340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3145_13350	COG2076	Multidrug Resistance protein
BsBEST3145_13360	COG2076	Multidrug Resistance protein
BsBEST3145_13370	COG0788	formyltetrahydrofolate deformylase activity
BsBEST3145_13380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3145_13390	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BsBEST3145_13400	COG1764	response to oxidative stress
BsBEST3145_13410	COG1846	Transcriptional regulator
BsBEST3145_13420	COG1764	response to oxidative stress
BsBEST3145_13440	COG0590	tRNA wobble adenosine to inosine editing
BsBEST3145_13450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3145_13460	COG1404	Belongs to the peptidase S8 family
BsBEST3145_13470	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3145_13480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BsBEST3145_13490	COG1122	ATPase activity
BsBEST3145_13500	COG4721	ABC-type cobalt transport system, permease component
BsBEST3145_13520	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_13530	COG3850	Histidine kinase
BsBEST3145_13530	COG5002	protein histidine kinase activity
BsBEST3145_13540	COG3212	peptidase
BsBEST3145_13550	COG3212	peptidase
BsBEST3145_13580	COG2239	Acts as a magnesium transporter
BsBEST3145_13590	COG0789	Transcriptional regulator
BsBEST3145_13620	COG1846	Transcriptional regulator
BsBEST3145_13630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3145_13640	COG0726	polysaccharide deacetylase
BsBEST3145_13650	COG1408	metallophosphoesterase
BsBEST3145_13670	COG0463	Glycosyl transferase, family 2
BsBEST3145_13680	COG3285	dna ligase
BsBEST3145_13680	COG1793	dna ligase
BsBEST3145_13690	COG3285	dna ligase
BsBEST3145_13690	COG1793	dna ligase
BsBEST3145_13700	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BsBEST3145_13710	COG3300	MHYT domain
BsBEST3145_13710	COG5001	Diguanylate cyclase
BsBEST3145_13720	COG0586	Pfam SNARE associated Golgi protein
BsBEST3145_13730	COG0861	Integral membrane protein TerC family
BsBEST3145_13740	COG1191	sigma factor activity
BsBEST3145_13780	COG0501	Belongs to the peptidase M48B family
BsBEST3145_13790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3145_13820	COG3594	Acyltransferase
BsBEST3145_13830	COG5002	protein histidine kinase activity
BsBEST3145_13840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BsBEST3145_13860	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BsBEST3145_13870	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BsBEST3145_13880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BsBEST3145_13890	COG0436	Aminotransferase
BsBEST3145_13900	COG1850	ribulose-bisphosphate carboxylase activity
BsBEST3145_13910	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BsBEST3145_13920	COG0235	Class ii aldolase
BsBEST3145_13930	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BsBEST3145_13940	COG3339	Conserved Protein
BsBEST3145_13970	COG3852	Histidine kinase
BsBEST3145_13980	COG1846	Transcriptional regulator
BsBEST3145_13990	COG1360	Flagellar Motor Protein
BsBEST3145_14000	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3145_14010	COG0542	response to heat
BsBEST3145_14020	COG3949	Membrane
BsBEST3145_14030	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BsBEST3145_14040	COG0720	synthase
BsBEST3145_14050	COG0602	queuosine metabolic process
BsBEST3145_14060	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BsBEST3145_14070	COG1733	regulation of RNA biosynthetic process
BsBEST3145_14080	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_14090	COG4641	Protein conserved in bacteria
BsBEST3145_14090	COG1388	LysM domain
BsBEST3145_14100	COG1388	LysM domain
BsBEST3145_14110	COG3858	chitin binding
BsBEST3145_14120	COG3858	chitin binding
BsBEST3145_14140	COG4873	Protein conserved in bacteria
BsBEST3145_14160	COG3773	Cell wall hydrolase
BsBEST3145_14170	COG2244	polysaccharide biosynthetic process
BsBEST3145_14180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_14190	COG2217	Heavy metal translocating P-type atpase
BsBEST3145_14210	COG0006	proline dipeptidase activity
BsBEST3145_14230	COG1609	Transcriptional regulator
BsBEST3145_14240	COG3711	transcriptional antiterminator
BsBEST3145_14250	COG2190	(PTS) system
BsBEST3145_14250	COG1263	PTS System
BsBEST3145_14250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3145_14260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3145_14270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BsBEST3145_14290	COG1533	DNA photolyase activity
BsBEST3145_14300	COG0456	acetyltransferase
BsBEST3145_14310	COG0840	transmembrane signaling receptor activity
BsBEST3145_14320	COG2084	Dehydrogenase
BsBEST3145_14330	COG2340	Cysteine-rich secretory protein family
BsBEST3145_14340	COG0768	penicillin binding
BsBEST3145_14350	COG4191	Histidine kinase
BsBEST3145_14360	COG0436	Aminotransferase
BsBEST3145_14380	COG0784	Response regulator, receiver
BsBEST3145_14380	COG0835	chemotaxis
BsBEST3145_14400	COG2814	Major facilitator Superfamily
BsBEST3145_14410	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3145_14420	COG1408	metallophosphoesterase
BsBEST3145_14430	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_14440	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_14450	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_14470	COG2200	EAL domain
BsBEST3145_14480	COG4703	Protein of unknown function (DUF1797)
BsBEST3145_14490	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BsBEST3145_14510	COG0517	IMP dehydrogenase activity
BsBEST3145_14520	COG0583	DNA-binding transcription factor activity
BsBEST3145_14530	COG0716	FMN binding
BsBEST3145_14550	COG0716	FMN binding
BsBEST3145_14560	COG2171	N-acyltransferase activity
BsBEST3145_14570	COG1473	amidohydrolase
BsBEST3145_14590	COG0668	transmembrane transport
BsBEST3145_14600	COG0450	alkyl hydroperoxide reductase
BsBEST3145_14610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_14640	COG0746	molybdenum cofactor guanylyltransferase activity
BsBEST3145_14650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3145_14660	COG0303	'Molybdopterin
BsBEST3145_14670	COG1763	Mo-molybdopterin cofactor biosynthetic process
BsBEST3145_14680	COG0314	molybdopterin synthase activity
BsBEST3145_14690	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BsBEST3145_14700	COG1132	(ABC) transporter
BsBEST3145_14710	COG1132	(ABC) transporter
BsBEST3145_14730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3145_14740	COG1136	(ABC) transporter
BsBEST3145_14750	COG0577	efflux transmembrane transporter activity
BsBEST3145_14760	COG1349	DNA-binding transcription factor activity
BsBEST3145_14770	COG1105	Belongs to the carbohydrate kinase PfkB family
BsBEST3145_14780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3145_14780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BsBEST3145_14780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3145_14790	COG0681	Belongs to the peptidase S26 family
BsBEST3145_14810	COG0488	(ABC) transporter
BsBEST3145_14820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3145_14830	COG2309	aminopeptidase activity
BsBEST3145_14850	COG1077	Cell shape determining protein MreB Mrl
BsBEST3145_14860	COG2002	toxin-antitoxin pair type II binding
BsBEST3145_14870	COG3852	Histidine kinase
BsBEST3145_14880	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BsBEST3145_14880	COG2105	PFAM AIG2 family protein
BsBEST3145_14890	COG0569	domain protein
BsBEST3145_14900	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BsBEST3145_14910	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3145_14920	COG5503	Protein of unknown function (DUF1447)
BsBEST3145_14930	COG0561	phosphatase activity
BsBEST3145_14940	COG0242	peptide deformylase activity
BsBEST3145_14960	COG0497	DNA recombination
BsBEST3145_14970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3145_14980	COG0022	dehydrogenase e1 component
BsBEST3145_14990	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3145_15000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3145_15010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_15020	COG1982	Orn Lys Arg decarboxylase major
BsBEST3145_15030	COG4476	Belongs to the UPF0223 family
BsBEST3145_15040	COG4493	Belongs to the UPF0637 family
BsBEST3145_15060	COG0483	inositol monophosphate 1-phosphatase activity
BsBEST3145_15080	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BsBEST3145_15120	COG1595	DNA-templated transcription, initiation
BsBEST3145_15160	COG1217	gtp-binding protein TYPA
BsBEST3145_15180	COG4896	Protein conserved in bacteria
BsBEST3145_15200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BsBEST3145_15210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3145_15220	COG2066	Belongs to the glutaminase family
BsBEST3145_15230	COG4838	Belongs to the UPF0358 family
BsBEST3145_15250	COG0772	Belongs to the SEDS family
BsBEST3145_15260	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BsBEST3145_15270	COG1612	heme a metabolic process
BsBEST3145_15280	COG0109	protoheme IX farnesyltransferase activity
BsBEST3145_15290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3145_15290	COG2010	Cytochrome c
BsBEST3145_15300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3145_15310	COG1845	cytochrome c oxidase, subunit III
BsBEST3145_15320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3145_15330	COG3336	cytochrome c oxidase
BsBEST3145_15350	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BsBEST3145_15360	COG2340	Cysteine-rich secretory protein family
BsBEST3145_15390	COG3679	Belongs to the UPF0342 family
BsBEST3145_15400	COG4471	UPF0298 protein
BsBEST3145_15410	COG0742	ribosomal rna small subunit methyltransferase
BsBEST3145_15420	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BsBEST3145_15430	COG3314	Sporulation integral membrane protein YlbJ
BsBEST3145_15440	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3145_15450	COG3480	Lon protease (S16) C-terminal proteolytic domain
BsBEST3145_15460	COG1323	Belongs to the UPF0348 family
BsBEST3145_15480	COG1399	metal-binding, possibly nucleic acid-binding protein
BsBEST3145_15510	COG0454	-acetyltransferase
BsBEST3145_15520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BsBEST3145_15530	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BsBEST3145_15540	COG2001	Belongs to the MraZ family
BsBEST3145_15550	COG0275	rRNA processing
BsBEST3145_15560	COG4839	cell division protein FtsL
BsBEST3145_15570	COG0768	penicillin binding
BsBEST3145_15580	COG0768	penicillin binding
BsBEST3145_15590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BsBEST3145_15600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3145_15610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3145_15620	COG0772	Belongs to the SEDS family
BsBEST3145_15630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3145_15640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BsBEST3145_15650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BsBEST3145_15660	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3145_15670	COG3879	Bacterial protein of unknown function (DUF881)
BsBEST3145_15680	COG3856	small basic protein
BsBEST3145_15690	COG0849	cell division
BsBEST3145_15700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BsBEST3145_15710	COG1404	Belongs to the peptidase S8 family
BsBEST3145_15710	COG4412	M6 family metalloprotease domain protein
BsBEST3145_15730	COG1191	sigma factor activity
BsBEST3145_15740	COG1191	sigma factor activity
BsBEST3145_15750	COG1119	ATPase activity
BsBEST3145_15760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3145_15770	COG1873	PFAM PRC-barrel domain
BsBEST3145_15780	COG1496	oxidoreductase activity
BsBEST3145_15790	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BsBEST3145_15800	COG1799	cell septum assembly
BsBEST3145_15810	COG0762	integral membrane protein
BsBEST3145_15820	COG2302	S4 RNA-binding domain
BsBEST3145_15830	COG3599	regulation of cell shape
BsBEST3145_15840	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BsBEST3145_15850	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3145_15860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BsBEST3145_15870	COG0564	pseudouridine synthase activity
BsBEST3145_15880	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BsBEST3145_15890	COG2233	PERMEase
BsBEST3145_15900	COG0540	Belongs to the ATCase OTCase family
BsBEST3145_15910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3145_15920	COG0505	Belongs to the CarA family
BsBEST3145_15930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BsBEST3145_15940	COG0543	2 iron, 2 sulfur cluster binding
BsBEST3145_15950	COG0167	dihydroorotate dehydrogenase activity
BsBEST3145_15960	COG0284	orotidine-5'-phosphate decarboxylase activity
BsBEST3145_15970	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BsBEST3145_15980	COG0175	sulfate reduction
BsBEST3145_15990	COG0306	phosphate transporter
BsBEST3145_16000	COG2046	Belongs to the sulfate adenylyltransferase family
BsBEST3145_16010	COG0529	Catalyzes the synthesis of activated sulfate
BsBEST3145_16020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BsBEST3145_16030	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BsBEST3145_16040	COG1648	precorrin-2 dehydrogenase activity
BsBEST3145_16050	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BsBEST3145_16060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3145_16070	COG1561	YicC-like family, N-terminal region
BsBEST3145_16090	COG0194	GDP metabolic process
BsBEST3145_16100	COG1758	RNA polymerase activity
BsBEST3145_16110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3145_16120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BsBEST3145_16130	COG0242	peptide deformylase activity
BsBEST3145_16140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BsBEST3145_16150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3145_16150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BsBEST3145_16160	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BsBEST3145_16170	COG0631	protein serine/threonine phosphatase activity
BsBEST3145_16180	COG0515	serine threonine protein kinase
BsBEST3145_16180	COG2815	serine threonine protein kinase
BsBEST3145_16190	COG1162	GTPase activity
BsBEST3145_16200	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BsBEST3145_16210	COG1564	THIamine pyrophosphokinase
BsBEST3145_16220	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BsBEST3145_16230	COG1302	Protein conserved in bacteria
BsBEST3145_16240	COG1461	Dihydroxyacetone kinase
BsBEST3145_16250	COG1760	l-serine dehydratase
BsBEST3145_16260	COG1760	l-serine dehydratase
BsBEST3145_16270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BsBEST3145_16280	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3145_16280	COG1349	DNA-binding transcription factor activity
BsBEST3145_16290	COG0416	fatty acid biosynthetic process
BsBEST3145_16300	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3145_16310	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_16330	COG0571	ribonuclease III activity
BsBEST3145_16340	COG1196	nuclear chromosome segregation
BsBEST3145_16350	COG0552	protein localization to endoplasmic reticulum
BsBEST3145_16370	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BsBEST3145_16380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BsBEST3145_16390	COG0228	four-way junction DNA binding
BsBEST3145_16400	COG1837	Belongs to the UPF0109 family
BsBEST3145_16420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BsBEST3145_16430	COG0336	Belongs to the RNA methyltransferase TrmD family
BsBEST3145_16440	COG0335	large ribosomal subunit rRNA binding
BsBEST3145_16450	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3145_16460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3145_16480	COG2257	FlhB HrpN YscU SpaS Family
BsBEST3145_16490	COG0045	succinate-CoA ligase (ADP-forming) activity
BsBEST3145_16500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BsBEST3145_16510	COG0758	DNA mediated transformation
BsBEST3145_16520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BsBEST3145_16530	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BsBEST3145_16540	COG4974	Belongs to the 'phage' integrase family
BsBEST3145_16550	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BsBEST3145_16560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BsBEST3145_16570	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3145_16580	COG1815	bacterial-type flagellum-dependent cell motility
BsBEST3145_16590	COG1558	bacterial-type flagellum-dependent cell motility
BsBEST3145_16600	COG1677	Flagellar hook-basal body complex protein FliE
BsBEST3145_16610	COG1766	The M ring may be actively involved in energy transduction
BsBEST3145_16620	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3145_16630	COG1317	bacterial-type flagellum organization
BsBEST3145_16640	COG1157	protein secretion by the type III secretion system
BsBEST3145_16650	COG2882	bacterial-type flagellum organization
BsBEST3145_16660	COG3334	PFAM MgtE intracellular
BsBEST3145_16670	COG3144	bacterial-type flagellum assembly
BsBEST3145_16680	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BsBEST3145_16690	COG4786	Flagellar basal body rod
BsBEST3145_16700	COG1582	Flagellar protein (FlbD)
BsBEST3145_16710	COG1580	Controls the rotational direction of flagella during chemotaxis
BsBEST3145_16720	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3145_16730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BsBEST3145_16730	COG1776	CheC inhibitor of MCP methylation
BsBEST3145_16740	COG2201	protein-glutamate methylesterase activity
BsBEST3145_16750	COG3190	flagellar
BsBEST3145_16760	COG1338	Plays a role in the flagellum-specific transport system
BsBEST3145_16770	COG1987	bacterial-type flagellum assembly
BsBEST3145_16780	COG1684	flagellar biosynthetic protein fliR
BsBEST3145_16790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3145_16800	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BsBEST3145_16810	COG1419	protein localization to endoplasmic reticulum
BsBEST3145_16820	COG0455	bacterial-type flagellum organization
BsBEST3145_16830	COG2201	protein-glutamate methylesterase activity
BsBEST3145_16840	COG2198	Histidine kinase
BsBEST3145_16840	COG0643	Histidine kinase
BsBEST3145_16850	COG0835	chemotaxis
BsBEST3145_16860	COG1776	CheC inhibitor of MCP methylation
BsBEST3145_16870	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BsBEST3145_16880	COG1191	sigma factor activity
BsBEST3145_16900	COG0052	Belongs to the universal ribosomal protein uS2 family
BsBEST3145_16910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BsBEST3145_16920	COG0528	UMP kinase activity
BsBEST3145_16930	COG0233	cytoplasmic translational termination
BsBEST3145_16940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BsBEST3145_16950	COG4589	Belongs to the CDS family
BsBEST3145_16960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BsBEST3145_16970	COG0750	zinc metalloprotease
BsBEST3145_16980	COG0442	prolyl-tRNA aminoacylation
BsBEST3145_16990	COG2176	DNA-directed DNA polymerase activity
BsBEST3145_17000	COG0779	Required for maturation of 30S ribosomal subunits
BsBEST3145_17010	COG0195	Participates in both transcription termination and antitermination
BsBEST3145_17020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BsBEST3145_17030	COG1358	cellular component organization or biogenesis
BsBEST3145_17040	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BsBEST3145_17050	COG1550	Protein conserved in bacteria
BsBEST3145_17060	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BsBEST3145_17070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BsBEST3145_17080	COG0196	riboflavin kinase activity
BsBEST3145_17090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BsBEST3145_17100	COG1185	polyribonucleotide nucleotidyltransferase activity
BsBEST3145_17110	COG0726	polysaccharide deacetylase
BsBEST3145_17120	COG0612	Peptidase, M16
BsBEST3145_17130	COG1873	PFAM PRC-barrel domain
BsBEST3145_17140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3145_17150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BsBEST3145_17160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BsBEST3145_17170	COG0527	aspartate kinase activity
BsBEST3145_17180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BsBEST3145_17190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BsBEST3145_17200	COG0740	serine-type endopeptidase activity
BsBEST3145_17220	COG4980	gas vesicle protein
BsBEST3145_17220	COG1674	ftsk spoiiie
BsBEST3145_17230	COG2188	Transcriptional regulator
BsBEST3145_17240	COG2814	Major facilitator Superfamily
BsBEST3145_17250	COG0612	Peptidase, M16
BsBEST3145_17260	COG0612	Peptidase, M16
BsBEST3145_17270	COG0300	oxidoreductase activity
BsBEST3145_17310	COG1426	Protein conserved in bacteria
BsBEST3145_17320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BsBEST3145_17330	COG1058	Belongs to the CinA family
BsBEST3145_17330	COG1546	Belongs to the CinA family
BsBEST3145_17340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BsBEST3145_17350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3145_17360	COG1418	mRNA catabolic process
BsBEST3145_17370	COG1692	metallophosphoesterase
BsBEST3145_17380	COG2359	stage V sporulation protein S
BsBEST3145_17390	COG1063	alcohol dehydrogenase
BsBEST3145_17400	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3145_17410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3145_17420	COG4550	Control of competence regulator ComK, YlbF/YmcA
BsBEST3145_17440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BsBEST3145_17450	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BsBEST3145_17480	COG3226	Transcriptional regulator
BsBEST3145_17490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3145_17510	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3145_17520	COG3321	synthase
BsBEST3145_17530	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BsBEST3145_17530	COG2070	2-Nitropropane dioxygenase
BsBEST3145_17540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3145_17550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BsBEST3145_17560	COG3425	synthase
BsBEST3145_17570	COG1024	Enoyl-CoA hydratase
BsBEST3145_17580	COG1024	Enoyl-CoA hydratase
BsBEST3145_17590	COG0300	oxidoreductase activity
BsBEST3145_17590	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3145_17590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_17590	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_17590	COG3321	synthase
BsBEST3145_17600	COG3321	synthase
BsBEST3145_17600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3145_17600	COG0300	oxidoreductase activity
BsBEST3145_17600	COG4221	oxidoreductase activity
BsBEST3145_17610	COG3321	synthase
BsBEST3145_17610	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_17610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_17610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3145_17610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3145_17620	COG3321	synthase
BsBEST3145_17620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_17620	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_17620	COG4221	oxidoreductase activity
BsBEST3145_17630	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_17630	COG4221	oxidoreductase activity
BsBEST3145_17630	COG3321	synthase
BsBEST3145_17630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_17640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3145_17640	COG3321	synthase
BsBEST3145_17640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BsBEST3145_17640	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3145_17650	COG2124	cytochrome p450
BsBEST3145_17670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3145_17680	COG1404	Belongs to the peptidase S8 family
BsBEST3145_17690	COG4195	phage-related replication protein
BsBEST3145_17700	COG1764	response to oxidative stress
BsBEST3145_17710	COG2076	Multidrug Resistance protein
BsBEST3145_17720	COG2076	Multidrug Resistance protein
BsBEST3145_17750	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BsBEST3145_17760	COG1923	regulation of RNA biosynthetic process
BsBEST3145_17790	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3145_17800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3145_17810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3145_17820	COG4112	unkown
BsBEST3145_17830	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_17840	COG0464	growth
BsBEST3145_17850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BsBEST3145_17860	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BsBEST3145_17870	COG0789	Transcriptional regulator
BsBEST3145_17880	COG0174	glutamine synthetase
BsBEST3145_17920	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3145_17940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3145_17990	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3145_18000	COG2211	Major facilitator Superfamily
BsBEST3145_18010	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3145_18020	COG1940	carbohydrate kinase activity
BsBEST3145_18030	COG2115	Belongs to the xylose isomerase family
BsBEST3145_18040	COG1070	Carbohydrate kinase
BsBEST3145_18050	COG1525	nuclease
BsBEST3145_18060	COG2814	Major facilitator Superfamily
BsBEST3145_18070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BsBEST3145_18090	COG0756	dUTP diphosphatase activity
BsBEST3145_18140	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3145_18190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BsBEST3145_18210	COG3832	glyoxalase III activity
BsBEST3145_18230	COG0697	spore germination
BsBEST3145_18240	COG0531	amino acid
BsBEST3145_18300	COG4195	phage-related replication protein
BsBEST3145_18320	COG0346	lactoylglutathione lyase activity
BsBEST3145_18330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BsBEST3145_18340	COG1388	LysM domain
BsBEST3145_18350	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3145_18360	COG4224	UPF0291 protein
BsBEST3145_18370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BsBEST3145_18390	COG3763	UPF0154 protein
BsBEST3145_18410	COG0785	Cytochrome C biogenesis protein
BsBEST3145_18420	COG2201	protein-glutamate methylesterase activity
BsBEST3145_18430	COG4846	Membrane protein involved in cytochrome C biogenesis
BsBEST3145_18450	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3145_18480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BsBEST3145_18490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_18530	COG0824	Thioesterase
BsBEST3145_18550	COG4841	protein insertion into membrane
BsBEST3145_18560	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BsBEST3145_18580	COG1832	CoA-binding protein
BsBEST3145_18590	COG0187	DNA topoisomerase II activity
BsBEST3145_18600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BsBEST3145_18630	COG1115	amino acid carrier protein
BsBEST3145_18640	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BsBEST3145_18660	COG5520	Belongs to the glycosyl hydrolase 30 family
BsBEST3145_18670	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3145_18680	COG2246	polysaccharide biosynthetic process
BsBEST3145_18690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3145_18700	COG0586	Pfam SNARE associated Golgi protein
BsBEST3145_18710	COG2404	hydrolase activity, acting on ester bonds
BsBEST3145_18720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3145_18730	COG1024	Enoyl-CoA hydratase
BsBEST3145_18740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3145_18750	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3145_18760	COG0439	Biotin carboxylase
BsBEST3145_18770	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3145_18780	COG1960	acyl-CoA dehydrogenase activity
BsBEST3145_18800	COG1649	PFAM Uncharacterised BCR, COG1649
BsBEST3145_18820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_18820	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BsBEST3145_18830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_18840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_18850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_18860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_18870	COG2027	D-alanyl-D-alanine carboxypeptidase
BsBEST3145_18880	COG2017	converts alpha-aldose to the beta-anomer
BsBEST3145_18890	COG0534	Mate efflux family protein
BsBEST3145_18910	COG0582	viral genome integration into host DNA
BsBEST3145_18920	COG0166	Belongs to the GPI family
BsBEST3145_18930	COG0405	Gamma-glutamyltransferase
BsBEST3145_18940	COG0583	DNA-binding transcription factor activity
BsBEST3145_18950	COG0604	alcohol dehydrogenase
BsBEST3145_18960	COG0493	'glutamate synthase
BsBEST3145_18970	COG0067	glutamate synthase
BsBEST3145_18970	COG0069	glutamate synthase activity
BsBEST3145_18970	COG0070	glutamate synthase
BsBEST3145_18980	COG0583	DNA-binding transcription factor activity
BsBEST3145_18990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BsBEST3145_19000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3145_19020	COG0300	oxidoreductase activity
BsBEST3145_19030	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3145_19050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3145_19060	COG2814	Major facilitator Superfamily
BsBEST3145_19070	COG1070	Carbohydrate kinase
BsBEST3145_19080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3145_19090	COG0243	molybdopterin cofactor binding
BsBEST3145_19140	COG0840	transmembrane signaling receptor activity
BsBEST3145_19140	COG5278	phosphoserine phosphatase activity
BsBEST3145_19150	COG2368	4-hydroxyphenylacetate
BsBEST3145_19160	COG4305	rare lipoprotein A
BsBEST3145_19170	COG3619	membrane
BsBEST3145_19180	COG3866	Pectate lyase
BsBEST3145_19190	COG2135	peptidase activity
BsBEST3145_19210	COG2140	Oxalate decarboxylase
BsBEST3145_19230	COG0456	acetyltransferase
BsBEST3145_19260	COG2720	vancomycin resistance protein
BsBEST3145_19280	COG3655	Transcriptional regulator
BsBEST3145_19290	COG3739	integral membrane protein
BsBEST3145_19300	COG0583	DNA-binding transcription factor activity
BsBEST3145_19310	COG0697	spore germination
BsBEST3145_19330	COG0693	protein deglycase activity
BsBEST3145_19340	COG2367	Beta-lactamase
BsBEST3145_19380	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3145_19380	COG3848	Pyruvate phosphate dikinase
BsBEST3145_19390	COG0726	polysaccharide deacetylase
BsBEST3145_19400	COG2314	TM2 domain
BsBEST3145_19410	COG1396	sequence-specific DNA binding
BsBEST3145_19440	COG2135	peptidase activity
BsBEST3145_19500	COG0457	Tetratricopeptide repeat
BsBEST3145_19520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3145_19530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3145_19560	COG5290	Psort location Cytoplasmic, score
BsBEST3145_19610	COG5444	nuclease activity
BsBEST3145_19620	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3145_19630	COG1231	oxidoreductase activity
BsBEST3145_19640	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3145_19650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3145_19660	COG2207	Transcriptional regulator
BsBEST3145_19660	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3145_19670	COG0456	acetyltransferase
BsBEST3145_19680	COG1309	transcriptional regulator
BsBEST3145_19690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3145_19700	COG3708	Transcriptional regulator
BsBEST3145_19710	COG2378	regulation of single-species biofilm formation
BsBEST3145_19720	COG0640	Transcriptional regulator
BsBEST3145_19730	COG0741	lytic transglycosylase activity
BsBEST3145_19740	COG2322	membrane
BsBEST3145_19770	COG1619	proteins homologs of microcin C7 resistance protein MccF
BsBEST3145_19780	COG3239	Fatty acid desaturase
BsBEST3145_19790	COG4585	Histidine kinase
BsBEST3145_19800	COG2197	response regulator
BsBEST3145_19810	COG3584	3D domain protein
BsBEST3145_19810	COG1388	LysM domain
BsBEST3145_19820	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3145_19830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3145_19840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3145_19870	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3145_19920	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_19930	COG1657	PFAM Prenyltransferase squalene oxidase
BsBEST3145_19940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3145_19950	COG0733	neurotransmitter:sodium symporter activity
BsBEST3145_19960	COG0385	Bile acid
BsBEST3145_19970	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3145_19980	COG0567	Dehydrogenase, E1 component
BsBEST3145_19990	COG4548	von Willebrand factor, type A
BsBEST3145_20000	COG0714	Associated with various cellular activities
BsBEST3145_20010	COG2032	superoxide dismutase activity
BsBEST3145_20020	COG1388	LysM domain
BsBEST3145_20020	COG0791	NLP P60 protein
BsBEST3145_20030	COG1819	glycosyl
BsBEST3145_20040	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BsBEST3145_20050	COG0534	Mate efflux family protein
BsBEST3145_20060	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3145_20070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3145_20080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3145_20100	COG2962	Rard protein
BsBEST3145_20130	COG2610	gluconate transmembrane transporter activity
BsBEST3145_20140	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3145_20150	COG1733	regulation of RNA biosynthetic process
BsBEST3145_20160	COG0778	Nitroreductase
BsBEST3145_20170	COG0400	carboxylic ester hydrolase activity
BsBEST3145_20180	COG0346	lactoylglutathione lyase activity
BsBEST3145_20200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3145_20210	COG0793	Belongs to the peptidase S41A family
BsBEST3145_20210	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_20220	COG2226	methyltransferase
BsBEST3145_20240	COG1876	peptidase activity
BsBEST3145_20250	COG0813	purine-nucleoside phosphorylase activity
BsBEST3145_20280	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3145_20320	COG4479	Belongs to the UPF0346 family
BsBEST3145_20340	COG1509	lysine 2,3-aminomutase activity
BsBEST3145_20350	COG0456	acetyltransferase
BsBEST3145_20360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3145_20370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3145_20380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3145_20390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3145_20420	COG0456	acetyltransferase
BsBEST3145_20430	COG0463	Glycosyl transferase, family 2
BsBEST3145_20460	COG4641	Protein conserved in bacteria
BsBEST3145_20470	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BsBEST3145_20480	COG1086	Polysaccharide biosynthesis protein
BsBEST3145_20500	COG3331	DNA recombination
BsBEST3145_20590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3145_20650	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BsBEST3145_20660	COG0756	dUTP diphosphatase activity
BsBEST3145_20670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_20680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3145_20700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3145_20720	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3145_20720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3145_20730	COG1372	Participates in initiation and elongation during chromosome replication
BsBEST3145_20730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BsBEST3145_20740	COG1780	Probably involved in ribonucleotide reductase function
BsBEST3145_20920	COG0270	DNA (cytosine-5-)-methyltransferase activity
BsBEST3145_20940	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BsBEST3145_20950	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BsBEST3145_21000	COG3584	3D domain protein
BsBEST3145_21010	COG0587	DNA-directed DNA polymerase activity
BsBEST3145_21020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3145_21030	COG0358	DNA primase activity
BsBEST3145_21040	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3145_21060	COG2887	Belongs to the helicase family. UvrD subfamily
BsBEST3145_21120	COG3420	alginic acid biosynthetic process
BsBEST3145_21120	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3145_21130	COG4195	phage-related replication protein
BsBEST3145_21160	COG2135	peptidase activity
BsBEST3145_21170	COG1793	dna ligase
BsBEST3145_21270	COG4474	Belongs to the UPF0398 family
BsBEST3145_21290	COG1388	LysM domain
BsBEST3145_21330	COG3646	Phage regulatory protein
BsBEST3145_21330	COG3645	SOS response
BsBEST3145_21440	COG3655	Transcriptional regulator
BsBEST3145_21470	COG0582	viral genome integration into host DNA
BsBEST3145_21630	COG3655	Transcriptional regulator
BsBEST3145_21700	COG1395	domain, Protein
BsBEST3145_21740	COG0776	regulation of translation
BsBEST3145_21800	COG4373	Mu-like prophage FluMu protein gp28
BsBEST3145_22000	COG0582	viral genome integration into host DNA
BsBEST3145_22060	COG1196	nuclear chromosome segregation
BsBEST3145_22060	COG0739	heme binding
BsBEST3145_22060	COG0741	lytic transglycosylase activity
BsBEST3145_22080	COG2433	Pfam Transposase IS66
BsBEST3145_22100	COG4632	Exopolysaccharide biosynthesis protein
BsBEST3145_22100	COG5434	Belongs to the glycosyl hydrolase 28 family
BsBEST3145_22130	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_22160	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3145_22170	COG0463	Glycosyl transferase, family 2
BsBEST3145_22180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_22190	COG3271	cysteine-type peptidase activity
BsBEST3145_22190	COG2274	protein secretion by the type I secretion system
BsBEST3145_22220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3145_22270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BsBEST3145_22300	COG5444	nuclease activity
BsBEST3145_22310	COG4282	regulation of fungal-type cell wall biogenesis
BsBEST3145_22330	COG1525	nuclease
BsBEST3145_22350	COG2746	aminoglycoside 3-N-acetyltransferase activity
BsBEST3145_22400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3145_22410	COG1086	Polysaccharide biosynthesis protein
BsBEST3145_22420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3145_22430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BsBEST3145_22440	COG1846	Transcriptional regulator
BsBEST3145_22450	COG0534	Mate efflux family protein
BsBEST3145_22470	COG4698	Protein conserved in bacteria
BsBEST3145_22480	COG2755	lipolytic protein G-D-S-L family
BsBEST3145_22490	COG1999	signal sequence binding
BsBEST3145_22510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BsBEST3145_22520	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3145_22530	COG1272	protein, Hemolysin III
BsBEST3145_22540	COG0204	Acyl-transferase
BsBEST3145_22550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3145_22560	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BsBEST3145_22570	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3145_22590	COG2136	Putative SAM-dependent methyltransferase
BsBEST3145_22590	COG2521	methyltransferase
BsBEST3145_22610	COG0129	dihydroxy-acid dehydratase activity
BsBEST3145_22620	COG1413	lyase activity
BsBEST3145_22630	COG1418	mRNA catabolic process
BsBEST3145_22640	COG0386	Belongs to the glutathione peroxidase family
BsBEST3145_22650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BsBEST3145_22660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BsBEST3145_22670	COG1278	Cold shock
BsBEST3145_22710	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3145_22720	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BsBEST3145_22730	COG0328	RNA-DNA hybrid ribonuclease activity
BsBEST3145_22750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3145_22780	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3145_22790	COG1755	Isoprenylcysteine carboxyl methyltransferase
BsBEST3145_22800	COG3424	synthase
BsBEST3145_22810	COG2233	PERMEase
BsBEST3145_22820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3145_22830	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BsBEST3145_22850	COG0800	Aldolase
BsBEST3145_22860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3145_22870	COG1609	Transcriptional regulator
BsBEST3145_22880	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BsBEST3145_22890	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_22900	COG1199	ATP-dependent helicase activity
BsBEST3145_22920	COG0116	Belongs to the methyltransferase superfamily
BsBEST3145_22940	COG4474	Belongs to the UPF0398 family
BsBEST3145_22950	COG3359	exonuclease
BsBEST3145_22960	COG1205	dead DEAH box helicase
BsBEST3145_22960	COG1111	helicase
BsBEST3145_22970	COG2190	(PTS) system
BsBEST3145_22980	COG0071	Belongs to the small heat shock protein (HSP20) family
BsBEST3145_23040	COG3331	DNA recombination
BsBEST3145_23050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3145_23050	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3145_23070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BsBEST3145_23080	COG3935	DnaD domain protein
BsBEST3145_23090	COG0017	Asparaginyl-tRNA synthetase
BsBEST3145_23100	COG0436	Aminotransferase
BsBEST3145_23110	COG5353	protein conserved in bacteria
BsBEST3145_23130	COG1199	ATP-dependent helicase activity
BsBEST3145_23130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BsBEST3145_23140	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BsBEST3145_23150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BsBEST3145_23160	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BsBEST3145_23170	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BsBEST3145_23170	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BsBEST3145_23180	COG0617	tRNA 3'-terminal CCA addition
BsBEST3145_23190	COG0438	transferase activity, transferring glycosyl groups
BsBEST3145_23200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BsBEST3145_23210	COG1803	Methylglyoxal synthase
BsBEST3145_23220	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BsBEST3145_23230	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3145_23240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3145_23260	COG4347	Protein of unknown function (DUF1405)
BsBEST3145_23270	COG2010	Cytochrome c
BsBEST3145_23270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3145_23280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BsBEST3145_23290	COG0723	plastoquinol--plastocyanin reductase activity
BsBEST3145_23310	COG5582	Belongs to the UPF0302 family
BsBEST3145_23320	COG0457	Tetratricopeptide repeat
BsBEST3145_23330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BsBEST3145_23340	COG0287	Prephenate dehydrogenase
BsBEST3145_23350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BsBEST3145_23360	COG0159	tryptophan synthase activity
BsBEST3145_23370	COG0133	tryptophan synthase activity
BsBEST3145_23380	COG0135	phosphoribosylanthranilate isomerase activity
BsBEST3145_23400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BsBEST3145_23410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BsBEST3145_23420	COG4401	Chorismate mutase type I
BsBEST3145_23430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BsBEST3145_23440	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BsBEST3145_23450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BsBEST3145_23460	COG0105	UTP biosynthetic process
BsBEST3145_23470	COG0142	geranyltranstransferase activity
BsBEST3145_23480	COG2226	methyltransferase
BsBEST3145_23490	COG0142	geranyltranstransferase activity
BsBEST3145_23510	COG0302	gtp cyclohydrolase
BsBEST3145_23520	COG0776	regulation of translation
BsBEST3145_23530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BsBEST3145_23560	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BsBEST3145_23570	COG1160	GTP binding
BsBEST3145_23620	COG1304	FMN binding
BsBEST3145_23630	COG0539	negative regulation of cytoplasmic translation
BsBEST3145_23640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BsBEST3145_23660	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BsBEST3145_23670	COG2959	enzyme of heme biosynthesis
BsBEST3145_23680	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_23680	COG3773	Cell wall hydrolase
BsBEST3145_23690	COG2339	peptidase activity
BsBEST3145_23700	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3145_23710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3145_23720	COG4862	establishment of competence for transformation
BsBEST3145_23730	COG1408	metallophosphoesterase
BsBEST3145_23740	COG1388	LysM domain
BsBEST3145_23750	COG1266	CAAX protease self-immunity
BsBEST3145_23760	COG0514	ATP-dependent DNA helicase (RecQ)
BsBEST3145_23770	COG4955	Helix-turn-helix domain
BsBEST3145_23780	COG1141	Ferredoxin
BsBEST3145_23790	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BsBEST3145_23810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BsBEST3145_23820	COG0710	3-dehydroquinate dehydratase activity
BsBEST3145_23840	COG1595	DNA-templated transcription, initiation
BsBEST3145_23850	COG5002	protein histidine kinase activity
BsBEST3145_23860	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_23870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3145_23880	COG1333	cytochrome c biogenesis protein
BsBEST3145_23890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_23900	COG1187	pseudouridine synthase activity
BsBEST3145_23910	COG0700	Nucleoside recognition
BsBEST3145_23920	COG2715	membrane protein required for spore maturation
BsBEST3145_23930	COG1686	Belongs to the peptidase S11 family
BsBEST3145_23950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BsBEST3145_23960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BsBEST3145_23970	COG1547	Domain of unknown function (DUF309)
BsBEST3145_23980	COG0456	acetyltransferase
BsBEST3145_23990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BsBEST3145_24000	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3145_24000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BsBEST3145_24010	COG0307	riboflavin synthase, alpha
BsBEST3145_24020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3145_24020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BsBEST3145_24040	COG0681	Belongs to the peptidase S26 family
BsBEST3145_24060	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BsBEST3145_24090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BsBEST3145_24100	COG4086	secreted protein
BsBEST3145_24110	COG0019	diaminopimelate decarboxylase activity
BsBEST3145_24120	COG0697	spore germination
BsBEST3145_24150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BsBEST3145_24190	COG1191	sigma factor activity
BsBEST3145_24200	COG2172	sigma factor antagonist activity
BsBEST3145_24210	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3145_24220	COG1686	Belongs to the peptidase S11 family
BsBEST3145_24230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BsBEST3145_24240	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BsBEST3145_24250	COG4974	Belongs to the 'phage' integrase family
BsBEST3145_24270	COG0735	belongs to the Fur family
BsBEST3145_24280	COG1300	Membrane
BsBEST3145_24300	COG0281	malic enzyme
BsBEST3145_24310	COG1757	Na H antiporter
BsBEST3145_24320	COG1027	Aspartate ammonia-lyase
BsBEST3145_24330	COG0252	asparaginase activity
BsBEST3145_24340	COG1396	sequence-specific DNA binding
BsBEST3145_24350	COG1379	DNA repair
BsBEST3145_24360	COG0494	nUDIX hydrolase
BsBEST3145_24380	COG0667	Aldo Keto reductase
BsBEST3145_24400	COG1073	alpha beta
BsBEST3145_24420	COG4918	Iron-sulphur cluster biosynthesis
BsBEST3145_24430	COG0456	acetyltransferase
BsBEST3145_24430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BsBEST3145_24440	COG2329	Antibiotic biosynthesis monooxygenase
BsBEST3145_24450	COG0456	acetyltransferase
BsBEST3145_24470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3145_24490	COG2211	Major facilitator Superfamily
BsBEST3145_24510	COG0346	lactoylglutathione lyase activity
BsBEST3145_24520	COG1072	(Pantothenic acid kinase))
BsBEST3145_24530	COG3048	D-serine ammonia-lyase activity
BsBEST3145_24540	COG0300	oxidoreductase activity
BsBEST3145_24550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3145_24560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3145_24570	COG4187	Peptidase family M20/M25/M40
BsBEST3145_24580	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3145_24590	COG0596	Alpha beta hydrolase
BsBEST3145_24600	COG1234	tRNA 3'-trailer cleavage
BsBEST3145_24610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BsBEST3145_24620	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3145_24630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BsBEST3145_24650	COG0706	membrane insertase activity
BsBEST3145_24660	COG3361	conserved protein (COG2071)
BsBEST3145_24670	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3145_24680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BsBEST3145_24690	COG0346	lactoylglutathione lyase activity
BsBEST3145_24700	COG1376	ErfK ybiS ycfS ynhG family protein
BsBEST3145_24710	COG4129	membrane
BsBEST3145_24720	COG1126	abc transporter atp-binding protein
BsBEST3145_24730	COG0765	amino acid transport
BsBEST3145_24740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3145_24760	COG1597	lipid kinase activity
BsBEST3145_24770	COG2814	Major facilitator Superfamily
BsBEST3145_24780	COG0789	Transcriptional regulator
BsBEST3145_24780	COG4978	Transcriptional regulator
BsBEST3145_24790	COG0508	dehydrogenase complex catalyzes the overall conversion of
BsBEST3145_24800	COG0022	dehydrogenase e1 component
BsBEST3145_24810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BsBEST3145_24820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BsBEST3145_24830	COG3426	butyrate kinase activity
BsBEST3145_24840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3145_24850	COG0280	phosphate acetyltransferase
BsBEST3145_24860	COG3290	protein histidine kinase activity
BsBEST3145_24860	COG3829	transcription factor binding
BsBEST3145_24880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BsBEST3145_24890	COG2079	MmgE PrpD family protein
BsBEST3145_24900	COG0372	Belongs to the citrate synthase family
BsBEST3145_24910	COG1960	acyl-CoA dehydrogenase activity
BsBEST3145_24920	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3145_24930	COG0183	Belongs to the thiolase family
BsBEST3145_24940	COG0584	glycerophosphoryl diester phosphodiesterase
BsBEST3145_24950	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_24970	COG1902	pentaerythritol trinitrate reductase activity
BsBEST3145_24980	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_24990	COG0750	zinc metalloprotease
BsBEST3145_25000	COG0497	DNA recombination
BsBEST3145_25010	COG1438	arginine binding
BsBEST3145_25020	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BsBEST3145_25030	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BsBEST3145_25040	COG0142	geranyltranstransferase activity
BsBEST3145_25050	COG1722	exodeoxyribonuclease VII activity
BsBEST3145_25060	COG1570	exodeoxyribonuclease VII activity
BsBEST3145_25070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BsBEST3145_25080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BsBEST3145_25090	COG1302	Protein conserved in bacteria
BsBEST3145_25100	COG0439	Biotin carboxylase
BsBEST3145_25110	COG0511	ligase activity, forming carbon-carbon bonds
BsBEST3145_25190	COG3854	ATPases associated with a variety of cellular activities
BsBEST3145_25210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BsBEST3145_25220	COG0006	proline dipeptidase activity
BsBEST3145_25230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BsBEST3145_25250	COG3872	metal-dependent enzyme
BsBEST3145_25270	COG1752	Esterase of the alpha-beta hydrolase superfamily
BsBEST3145_25280	COG1321	iron dependent repressor
BsBEST3145_25290	COG0095	Lipoate-protein ligase
BsBEST3145_25300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3145_25310	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3145_25320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BsBEST3145_25330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BsBEST3145_25340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3145_25370	COG1396	sequence-specific DNA binding
BsBEST3145_25390	COG0681	Belongs to the peptidase S26 family
BsBEST3145_25440	COG4940	Competence protein ComGF
BsBEST3145_25460	COG4970	Tfp pilus assembly protein FimT
BsBEST3145_25470	COG4537	Required for transformation and DNA binding
BsBEST3145_25480	COG1459	type II secretion system
BsBEST3145_25490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BsBEST3145_25500	COG0598	Magnesium transport protein CorA
BsBEST3145_25510	COG1253	flavin adenine dinucleotide binding
BsBEST3145_25520	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3145_25530	COG1393	Belongs to the ArsC family
BsBEST3145_25550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3145_25570	COG0011	TIGRFAM Protein of
BsBEST3145_25590	COG2866	Carboxypeptidase
BsBEST3145_25600	COG1368	sulfuric ester hydrolase activity
BsBEST3145_25610	COG1940	carbohydrate kinase activity
BsBEST3145_25620	COG4483	Protein conserved in bacteria
BsBEST3145_25630	COG0457	Tetratricopeptide repeat
BsBEST3145_25630	COG0705	Rhomboid family
BsBEST3145_25650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BsBEST3145_25670	COG0438	transferase activity, transferring glycosyl groups
BsBEST3145_25700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3145_25710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3145_25720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BsBEST3145_25730	COG0581	inorganic phosphate transmembrane transporter activity
BsBEST3145_25740	COG0573	inorganic phosphate transmembrane transporter activity
BsBEST3145_25750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BsBEST3145_25760	COG0768	penicillin binding
BsBEST3145_25770	COG0477	Major facilitator Superfamily
BsBEST3145_25780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BsBEST3145_25790	COG2839	Protein conserved in bacteria
BsBEST3145_25800	COG5521	maltodextrose utilization protein MalA
BsBEST3145_25820	COG1388	LysM domain
BsBEST3145_25830	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BsBEST3145_25840	COG4709	membrane
BsBEST3145_25850	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BsBEST3145_25860	COG0735	belongs to the Fur family
BsBEST3145_25870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3145_25890	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BsBEST3145_25900	COG0513	Belongs to the DEAD box helicase family
BsBEST3145_25920	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BsBEST3145_25930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BsBEST3145_25940	COG2384	SAM-dependent methyltransferase
BsBEST3145_25950	COG2010	Cytochrome c
BsBEST3145_25960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BsBEST3145_25970	COG0358	DNA primase activity
BsBEST3145_25980	COG1671	Belongs to the UPF0178 family
BsBEST3145_25990	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BsBEST3145_26000	COG0517	IMP dehydrogenase activity
BsBEST3145_26010	COG0751	glycine-tRNA ligase activity
BsBEST3145_26020	COG0752	glycyl-tRNA synthetase alpha subunit
BsBEST3145_26030	COG1381	Involved in DNA repair and RecF pathway recombination
BsBEST3145_26050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BsBEST3145_26060	COG0295	cytidine deaminase activity
BsBEST3145_26070	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BsBEST3145_26080	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BsBEST3145_26090	COG1480	7TM receptor with intracellular HD hydrolase
BsBEST3145_26100	COG1702	phosphate starvation-inducible protein PhoH
BsBEST3145_26110	COG0561	phosphatase activity
BsBEST3145_26140	COG4864	UPF0365 protein
BsBEST3145_26150	COG1030	water channel activity
BsBEST3145_26160	COG1610	YqeY-like protein
BsBEST3145_26180	COG1283	sodium-dependent phosphate transmembrane transporter activity
BsBEST3145_26190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BsBEST3145_26200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BsBEST3145_26210	COG2264	protein methyltransferase activity
BsBEST3145_26220	COG0484	heat shock protein binding
BsBEST3145_26230	COG0443	Heat shock 70 kDa protein
BsBEST3145_26240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BsBEST3145_26250	COG1420	regulation of RNA biosynthetic process
BsBEST3145_26260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BsBEST3145_26270	COG0481	GTPase activity
BsBEST3145_26290	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_26300	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BsBEST3145_26320	COG0268	Binds directly to 16S ribosomal RNA
BsBEST3145_26330	COG1466	dna polymerase III delta subunit
BsBEST3145_26350	COG2333	competence protein COMEC
BsBEST3145_26350	COG0658	competence protein
BsBEST3145_26370	COG2131	deaminase
BsBEST3145_26380	COG1555	photosystem II stabilization
BsBEST3145_26380	COG1596	polysaccharide export
BsBEST3145_26390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BsBEST3145_26400	COG2226	methyltransferase
BsBEST3145_26410	COG0799	negative regulation of ribosome biogenesis
BsBEST3145_26420	COG1713	HD superfamily hydrolase involved in NAD metabolism
BsBEST3145_26430	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BsBEST3145_26440	COG1534	Rna-binding protein
BsBEST3145_26450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BsBEST3145_26460	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BsBEST3145_26470	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BsBEST3145_26480	COG2755	lipolytic protein G-D-S-L family
BsBEST3145_26490	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_26490	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_26500	COG0398	Pfam SNARE associated Golgi protein
BsBEST3145_26510	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BsBEST3145_26530	COG3209	COG3209 Rhs family protein
BsBEST3145_26550	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BsBEST3145_26570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3145_26580	COG0798	PFAM Bile acid sodium symporter
BsBEST3145_26590	COG0346	lactoylglutathione lyase activity
BsBEST3145_26600	COG0640	Transcriptional regulator
BsBEST3145_26610	COG3403	YqcI/YcgG family
BsBEST3145_26620	COG0457	Tetratricopeptide repeat
BsBEST3145_26650	COG5444	nuclease activity
BsBEST3145_26700	COG5632	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_26700	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_26710	COG4824	toxin secretion phage lysis holin
BsBEST3145_26770	COG3778	Protein conserved in bacteria
BsBEST3145_26780	COG3299	homolog of phage Mu protein gp47
BsBEST3145_26790	COG3628	GPW Gp25 family protein
BsBEST3145_26810	COG4193	domain, Protein
BsBEST3145_26820	COG1652	LysM domain
BsBEST3145_26830	COG5280	Phage tail tape measure protein TP901
BsBEST3145_26830	COG3953	SLT domain
BsBEST3145_26960	COG4653	Phage capsid family
BsBEST3145_26970	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BsBEST3145_26990	COG2369	cell adhesion
BsBEST3145_27000	COG5518	Phage portal protein
BsBEST3145_27010	COG1783	phage Terminase large subunit
BsBEST3145_27020	COG5484	DNA packaging
BsBEST3145_27040	COG3677	Transposase
BsBEST3145_27070	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BsBEST3145_27090	COG1484	DNA-dependent DNA replication
BsBEST3145_27100	COG3935	DnaD domain protein
BsBEST3145_27110	COG3723	Recombinational DNA repair protein, rece pathway
BsBEST3145_27120	COG5377	YqaJ viral recombinase family
BsBEST3145_27180	COG1476	TRANSCRIPTIONal
BsBEST3145_27190	COG3620	sequence-specific DNA binding
BsBEST3145_27210	COG0563	adenylate kinase activity
BsBEST3145_27220	COG2856	Zn peptidase
BsBEST3145_27240	COG3223	Belongs to the PsiE family
BsBEST3145_27250	COG0642	Histidine kinase
BsBEST3145_27250	COG5002	protein histidine kinase activity
BsBEST3145_27260	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_27270	COG2311	Membrane
BsBEST3145_27280	COG0454	-acetyltransferase
BsBEST3145_27290	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3145_27310	COG0730	response to heat
BsBEST3145_27320	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3145_27330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3145_27330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3145_27340	COG0425	Belongs to the sulfur carrier protein TusA family
BsBEST3145_27340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3145_27350	COG2210	Belongs to the sulfur carrier protein TusA family
BsBEST3145_27360	COG1937	Protein conserved in bacteria
BsBEST3145_27390	COG0662	Cupin 2, conserved barrel domain protein
BsBEST3145_27410	COG4978	Transcriptional regulator
BsBEST3145_27410	COG0789	Transcriptional regulator
BsBEST3145_27420	COG2814	Major facilitator Superfamily
BsBEST3145_27430	COG0456	acetyltransferase
BsBEST3145_27440	COG1253	flavin adenine dinucleotide binding
BsBEST3145_27460	COG0697	spore germination
BsBEST3145_27470	COG0583	DNA-binding transcription factor activity
BsBEST3145_27480	COG2072	flavoprotein involved in K transport
BsBEST3145_27490	COG1230	cation diffusion facilitator family transporter
BsBEST3145_27500	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3145_27510	COG0583	DNA-binding transcription factor activity
BsBEST3145_27530	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3145_27540	COG1687	branched-chain amino acid
BsBEST3145_27550	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BsBEST3145_27560	COG1522	sequence-specific DNA binding
BsBEST3145_27570	COG2732	(Barnase) inhibitor
BsBEST3145_27580	COG2124	cytochrome p450
BsBEST3145_27610	COG1335	isochorismatase
BsBEST3145_27630	COG2318	DinB family
BsBEST3145_27650	COG2070	2-Nitropropane dioxygenase
BsBEST3145_27680	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3145_27710	COG3443	Belongs to the bacterial solute-binding protein 9 family
BsBEST3145_27720	COG1595	DNA-templated transcription, initiation
BsBEST3145_27730	COG0667	Aldo Keto reductase
BsBEST3145_27740	COG2851	Citrate transporter
BsBEST3145_27750	COG0583	DNA-binding transcription factor activity
BsBEST3145_27760	COG2828	Protein conserved in bacteria
BsBEST3145_27780	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_27790	COG5566	PFAM Mor transcription activator
BsBEST3145_27800	COG0596	Alpha beta hydrolase
BsBEST3145_27810	COG4991	sh3 domain protein
BsBEST3145_27820	COG4991	sh3 domain protein
BsBEST3145_27830	COG0346	lactoylglutathione lyase activity
BsBEST3145_27850	COG5577	PFAM Coat F domain
BsBEST3145_27860	COG1063	alcohol dehydrogenase
BsBEST3145_27880	COG5577	PFAM Coat F domain
BsBEST3145_27890	COG0789	Transcriptional regulator
BsBEST3145_27910	COG1064	alcohol dehydrogenase
BsBEST3145_27920	COG0693	protein deglycase activity
BsBEST3145_27930	COG1621	beta-fructofuranosidase activity
BsBEST3145_27940	COG3716	PTS system mannose fructose sorbose family IID component
BsBEST3145_27950	COG3715	PTS system
BsBEST3145_27960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3145_27970	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3145_27980	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BsBEST3145_27980	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BsBEST3145_27990	COG1113	amino acid transport
BsBEST3145_28000	COG1280	lysine exporter protein (LysE YggA)
BsBEST3145_28010	COG1378	Sugar-specific transcriptional regulator TrmB
BsBEST3145_28020	COG1595	DNA-templated transcription, initiation
BsBEST3145_28040	COG2755	lipolytic protein G-D-S-L family
BsBEST3145_28040	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BsBEST3145_28060	COG2124	cytochrome p450
BsBEST3145_28060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3145_28070	COG1309	transcriptional regulator
BsBEST3145_28080	COG2226	methyltransferase
BsBEST3145_28100	COG2116	formate transmembrane transporter activity
BsBEST3145_28110	COG5609	conserved protein (DUF2294)
BsBEST3145_28120	COG3383	formate dehydrogenase (NAD+) activity
BsBEST3145_28130	COG2427	Protein of unknown function (DUF1641)
BsBEST3145_28150	COG0626	cystathionine gamma-synthase activity
BsBEST3145_28160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3145_28170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BsBEST3145_28180	COG2226	methyltransferase
BsBEST3145_28210	COG0768	penicillin binding
BsBEST3145_28220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BsBEST3145_28230	COG0572	uridine kinase
BsBEST3145_28240	COG0826	peptidase U32
BsBEST3145_28250	COG0826	peptidase U32
BsBEST3145_28260	COG4122	O-methyltransferase activity
BsBEST3145_28270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BsBEST3145_28280	COG3906	Belongs to the UPF0473 family
BsBEST3145_28290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BsBEST3145_28300	COG4472	Bacterial protein of unknown function (DUF965)
BsBEST3145_28310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BsBEST3145_28320	COG0628	permease
BsBEST3145_28330	COG1126	abc transporter atp-binding protein
BsBEST3145_28340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3145_28350	COG0765	amino acid transport
BsBEST3145_28360	COG0765	amino acid transport
BsBEST3145_28390	COG3881	PFAM PRC-barrel domain
BsBEST3145_28400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BsBEST3145_28410	COG0457	Tetratricopeptide repeat
BsBEST3145_28420	COG0482	sulfurtransferase activity
BsBEST3145_28430	COG1104	cysteine desulfurase activity
BsBEST3145_28440	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3145_28450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BsBEST3145_28460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BsBEST3145_28470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BsBEST3145_28480	COG0124	histidyl-tRNA synthetase
BsBEST3145_28500	COG4991	sh3 domain protein
BsBEST3145_28500	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_28500	COG3103	Sh3 type 3 domain protein
BsBEST3145_28510	COG1490	D-aminoacyl-tRNA deacylase activity
BsBEST3145_28520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BsBEST3145_28530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BsBEST3145_28540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BsBEST3145_28540	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BsBEST3145_28550	COG5416	Lipopolysaccharide assembly protein A domain
BsBEST3145_28560	COG0490	domain, Protein
BsBEST3145_28570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3145_28570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BsBEST3145_28590	COG2244	polysaccharide biosynthetic process
BsBEST3145_28600	COG2323	membrane
BsBEST3145_28620	COG1862	Preprotein translocase
BsBEST3145_28630	COG0343	queuine tRNA-ribosyltransferase activity
BsBEST3145_28640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BsBEST3145_28660	COG2255	four-way junction helicase activity
BsBEST3145_28670	COG0632	four-way junction helicase activity
BsBEST3145_28690	COG2814	Major facilitator Superfamily
BsBEST3145_28700	COG0673	inositol 2-dehydrogenase activity
BsBEST3145_28710	COG2112	serine threonine protein kinase
BsBEST3145_28740	COG1115	amino acid carrier protein
BsBEST3145_28750	COG0217	transcriptional regulatory protein
BsBEST3145_28770	COG1388	LysM domain
BsBEST3145_28780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BsBEST3145_28790	COG0157	Belongs to the NadC ModD family
BsBEST3145_28800	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BsBEST3145_28810	COG1104	cysteine desulfurase activity
BsBEST3145_28820	COG1827	regulation of RNA biosynthetic process
BsBEST3145_28830	COG0077	Prephenate dehydratase
BsBEST3145_28840	COG4492	Belongs to the UPF0735 family
BsBEST3145_28850	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BsBEST3145_28860	COG3290	protein histidine kinase activity
BsBEST3145_28870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BsBEST3145_28880	COG2868	ribosomal protein
BsBEST3145_28890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BsBEST3145_28900	COG1994	Peptidase M50
BsBEST3145_28910	COG0739	heme binding
BsBEST3145_28920	COG2894	cell division
BsBEST3145_28930	COG0850	regulation of cytokinetic process
BsBEST3145_28940	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BsBEST3145_28960	COG1077	Cell shape determining protein MreB Mrl
BsBEST3145_28970	COG2003	Belongs to the UPF0758 family
BsBEST3145_28980	COG0424	maF-like protein
BsBEST3145_29000	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BsBEST3145_29010	COG0285	dihydrofolate synthase activity
BsBEST3145_29020	COG0525	valine-tRNA ligase activity
BsBEST3145_29040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3145_29050	COG1388	LysM domain
BsBEST3145_29060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BsBEST3145_29070	COG0113	porphobilinogen synthase activity
BsBEST3145_29080	COG1587	Uroporphyrinogen-III synthase
BsBEST3145_29090	COG0181	hydroxymethylbilane synthase activity
BsBEST3145_29100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BsBEST3145_29110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BsBEST3145_29130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BsBEST3145_29140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BsBEST3145_29150	COG1067	ATP-dependent peptidase activity
BsBEST3145_29150	COG0470	DNA polymerase III
BsBEST3145_29160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BsBEST3145_29170	COG0544	peptidyl-prolyl cis-trans isomerase activity
BsBEST3145_29180	COG1477	protein flavinylation
BsBEST3145_29180	COG0457	Tetratricopeptide repeat
BsBEST3145_29190	COG0066	3-isopropylmalate dehydratase activity
BsBEST3145_29200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BsBEST3145_29220	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BsBEST3145_29230	COG0473	3-isopropylmalate dehydrogenase activity
BsBEST3145_29240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BsBEST3145_29250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BsBEST3145_29260	COG0440	acetolactate synthase activity
BsBEST3145_29270	COG0028	Belongs to the TPP enzyme family
BsBEST3145_29290	COG0454	-acetyltransferase
BsBEST3145_29300	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BsBEST3145_29310	COG0622	Phosphoesterase
BsBEST3145_29320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BsBEST3145_29330	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BsBEST3145_29340	COG5401	PFAM Sporulation and spore germination
BsBEST3145_29350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BsBEST3145_29360	COG1846	Transcriptional regulator
BsBEST3145_29370	COG2197	response regulator
BsBEST3145_29380	COG0824	Thioesterase
BsBEST3145_29390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BsBEST3145_29400	COG1053	succinate dehydrogenase
BsBEST3145_29410	COG2009	succinate dehydrogenase
BsBEST3145_29420	COG1719	4-vinyl reductase, 4VR
BsBEST3145_29430	COG0527	aspartate kinase activity
BsBEST3145_29440	COG0322	excinuclease ABC activity
BsBEST3145_29450	COG3118	belongs to the thioredoxin family
BsBEST3145_29460	COG3534	alpha-L-arabinofuranosidase
BsBEST3145_29470	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BsBEST3145_29480	COG2086	electron transfer activity
BsBEST3145_29490	COG1024	Enoyl-CoA hydratase
BsBEST3145_29500	COG1309	transcriptional regulator
BsBEST3145_29510	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3145_29520	COG3766	membrane
BsBEST3145_29530	COG1193	negative regulation of DNA recombination
BsBEST3145_29540	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3145_29540	COG1796	DNA polymerase
BsBEST3145_29550	COG1286	toxin biosynthetic process
BsBEST3145_29560	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BsBEST3145_29570	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BsBEST3145_29580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3145_29580	COG0072	phenylalanine-tRNA ligase activity
BsBEST3145_29590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BsBEST3145_29600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BsBEST3145_29620	COG3835	regulator
BsBEST3145_29630	COG0277	FAD linked oxidase domain protein
BsBEST3145_29640	COG0247	lactate metabolic process
BsBEST3145_29650	COG0346	lactoylglutathione lyase activity
BsBEST3145_29670	COG1966	Carbon starvation protein
BsBEST3145_29680	COG3534	alpha-L-arabinofuranosidase
BsBEST3145_29690	COG0395	ABC-type sugar transport system, permease component
BsBEST3145_29700	COG1175	transmembrane transport
BsBEST3145_29710	COG1653	transport
BsBEST3145_29720	COG0371	Dehydrogenase
BsBEST3145_29730	COG0647	UMP catabolic process
BsBEST3145_29740	COG0235	Class ii aldolase
BsBEST3145_29750	COG1069	ribulokinase activity
BsBEST3145_29760	COG2160	L-arabinose isomerase activity
BsBEST3145_29770	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3145_29780	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3145_29790	COG1363	Peptidase, m42
BsBEST3145_29810	COG3326	Membrane
BsBEST3145_29820	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BsBEST3145_29830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BsBEST3145_29840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BsBEST3145_29860	COG1346	cytolysis
BsBEST3145_29870	COG1380	Effector of murein hydrolase LrgA
BsBEST3145_29880	COG3279	Response regulator of the LytR AlgR family
BsBEST3145_29890	COG3275	phosphorelay sensor kinase activity
BsBEST3145_29900	COG1011	Hydrolase
BsBEST3145_29910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3145_29930	COG0398	Pfam SNARE associated Golgi protein
BsBEST3145_29940	COG1484	DNA-dependent DNA replication
BsBEST3145_29950	COG3611	Membrane attachment protein
BsBEST3145_29960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BsBEST3145_29970	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BsBEST3145_29980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3145_29990	COG1733	regulation of RNA biosynthetic process
BsBEST3145_30000	COG2814	Major facilitator Superfamily
BsBEST3145_30010	COG0656	L-ascorbic acid biosynthetic process
BsBEST3145_30020	COG0237	dephospho-CoA kinase activity
BsBEST3145_30030	COG1971	Probably functions as a manganese efflux pump
BsBEST3145_30040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BsBEST3145_30050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3145_30050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BsBEST3145_30060	COG5002	protein histidine kinase activity
BsBEST3145_30070	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_30080	COG0039	L-malate dehydrogenase activity
BsBEST3145_30090	COG0538	isocitrate dehydrogenase activity
BsBEST3145_30100	COG0372	Belongs to the citrate synthase family
BsBEST3145_30110	COG2707	UPF0756 membrane protein
BsBEST3145_30120	COG0628	permease
BsBEST3145_30130	COG3030	protein affecting phage T7 exclusion by the F plasmid
BsBEST3145_30140	COG0469	pyruvate kinase activity
BsBEST3145_30150	COG0205	6-phosphofructokinase activity
BsBEST3145_30160	COG0825	malonyl-CoA metabolic process
BsBEST3145_30170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BsBEST3145_30180	COG0281	malic enzyme
BsBEST3145_30190	COG0587	DNA-directed DNA polymerase activity
BsBEST3145_30230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BsBEST3145_30250	COG4109	DRTGG domain
BsBEST3145_30260	COG0730	response to heat
BsBEST3145_30270	COG1473	amidohydrolase
BsBEST3145_30280	COG0196	riboflavin kinase activity
BsBEST3145_30290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_30300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BsBEST3145_30310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_30320	COG1126	abc transporter atp-binding protein
BsBEST3145_30330	COG0765	amino acid transport
BsBEST3145_30340	COG0765	amino acid transport
BsBEST3145_30350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3145_30360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3145_30370	COG0454	-acetyltransferase
BsBEST3145_30380	COG0583	DNA-binding transcription factor activity
BsBEST3145_30390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BsBEST3145_30400	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_30420	COG0165	Argininosuccinate lyase
BsBEST3145_30430	COG0137	argininosuccinate synthase activity
BsBEST3145_30440	COG0521	Mo-molybdopterin cofactor biosynthetic process
BsBEST3145_30450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BsBEST3145_30460	COG0827	DNA restriction-modification system
BsBEST3145_30470	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BsBEST3145_30480	COG3874	Sporulation protein YtfJ
BsBEST3145_30500	COG1714	RDD family
BsBEST3145_30510	COG0616	signal peptide processing
BsBEST3145_30520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BsBEST3145_30530	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BsBEST3145_30540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3145_30560	COG0301	tRNA thio-modification
BsBEST3145_30570	COG1104	cysteine desulfurase activity
BsBEST3145_30580	COG1114	Component of the transport system for branched-chain amino acids
BsBEST3145_30590	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BsBEST3145_30600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BsBEST3145_30610	COG1309	transcriptional regulator
BsBEST3145_30620	COG1956	GAF domain-containing protein
BsBEST3145_30630	COG2199	diguanylate cyclase activity
BsBEST3145_30630	COG2203	Gaf domain
BsBEST3145_30640	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BsBEST3145_30660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3145_30670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BsBEST3145_30680	COG0454	-acetyltransferase
BsBEST3145_30690	COG0517	IMP dehydrogenase activity
BsBEST3145_30700	COG0123	including yeast histone deacetylase and acetoin utilization protein
BsBEST3145_30710	COG1360	Flagellar Motor Protein
BsBEST3145_30720	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BsBEST3145_30730	COG1609	Transcriptional regulator
BsBEST3145_30740	COG1605	Chorismate mutase
BsBEST3145_30740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BsBEST3145_30750	COG3118	belongs to the thioredoxin family
BsBEST3145_30760	COG4980	gas vesicle protein
BsBEST3145_30770	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BsBEST3145_30780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BsBEST3145_30790	COG1674	ftsk spoiiie
BsBEST3145_30800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BsBEST3145_30810	COG4848	Belongs to the UPF0354 family
BsBEST3145_30820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_30840	COG1363	Peptidase, m42
BsBEST3145_30850	COG5584	Small secreted protein
BsBEST3145_30860	COG0281	malic enzyme
BsBEST3145_30870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3145_30880	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BsBEST3145_30900	COG0510	thiamine kinase activity
BsBEST3145_30910	COG1523	belongs to the glycosyl hydrolase 13 family
BsBEST3145_30920	COG1597	lipid kinase activity
BsBEST3145_30940	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BsBEST3145_30950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BsBEST3145_30960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3145_30970	COG2252	PERMEase
BsBEST3145_30980	COG4473	ABC transporter
BsBEST3145_30990	COG1131	(ABC) transporter
BsBEST3145_31010	COG1349	DNA-binding transcription factor activity
BsBEST3145_31020	COG1187	pseudouridine synthase activity
BsBEST3145_31030	COG2244	polysaccharide biosynthetic process
BsBEST3145_31040	COG2081	HI0933 family
BsBEST3145_31050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BsBEST3145_31070	COG5578	integral membrane protein
BsBEST3145_31080	COG0673	inositol 2-dehydrogenase activity
BsBEST3145_31090	COG1653	transport
BsBEST3145_31100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BsBEST3145_31110	COG4209	transmembrane transport
BsBEST3145_31120	COG2207	Transcriptional regulator
BsBEST3145_31130	COG2207	Transcriptional regulator
BsBEST3145_31140	COG1653	transport
BsBEST3145_31150	COG0395	ABC-type sugar transport system, permease component
BsBEST3145_31160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3145_31170	COG2124	cytochrome p450
BsBEST3145_31180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BsBEST3145_31190	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BsBEST3145_31200	COG0156	8-amino-7-oxononanoate synthase activity
BsBEST3145_31210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BsBEST3145_31220	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BsBEST3145_31230	COG1073	alpha beta
BsBEST3145_31240	COG1609	Transcriptional regulator
BsBEST3145_31250	COG1653	transport
BsBEST3145_31260	COG1175	transmembrane transport
BsBEST3145_31270	COG0395	ABC-type sugar transport system, permease component
BsBEST3145_31280	COG1486	melibiose metabolic process
BsBEST3145_31290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BsBEST3145_31300	COG0495	leucyl-tRNA aminoacylation
BsBEST3145_31320	COG2202	Pas domain
BsBEST3145_31320	COG1366	Belongs to the anti-sigma-factor antagonist family
BsBEST3145_31330	COG2814	Major facilitator Superfamily
BsBEST3145_31340	COG2433	Pfam Transposase IS66
BsBEST3145_31350	COG0577	efflux transmembrane transporter activity
BsBEST3145_31360	COG1136	(ABC) transporter
BsBEST3145_31370	COG2205	protein histidine kinase activity
BsBEST3145_31380	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_31390	COG0577	efflux transmembrane transporter activity
BsBEST3145_31400	COG1136	(ABC) transporter
BsBEST3145_31430	COG1131	(ABC) transporter
BsBEST3145_31440	COG1725	Transcriptional regulator
BsBEST3145_31460	COG1242	4 iron, 4 sulfur cluster binding
BsBEST3145_31470	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BsBEST3145_31490	COG2267	carboxylic ester hydrolase activity
BsBEST3145_31500	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BsBEST3145_31510	COG1113	amino acid transport
BsBEST3145_31520	COG0367	asparagine synthase
BsBEST3145_31530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BsBEST3145_31540	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BsBEST3145_31560	COG1506	peptidase
BsBEST3145_31570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BsBEST3145_31580	COG1116	anion transmembrane transporter activity
BsBEST3145_31590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BsBEST3145_31600	COG0494	nUDIX hydrolase
BsBEST3145_31610	COG4824	toxin secretion phage lysis holin
BsBEST3145_31620	COG0783	Belongs to the Dps family
BsBEST3145_31650	COG1854	S-ribosylhomocysteine lyase activity
BsBEST3145_31660	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BsBEST3145_31670	COG0288	reversible hydration of carbon dioxide
BsBEST3145_31680	COG0254	rRNA binding
BsBEST3145_31690	COG1271	oxidase subunit
BsBEST3145_31700	COG1294	oxidase, subunit
BsBEST3145_31720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3145_31730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BsBEST3145_31730	COG1321	iron dependent repressor
BsBEST3145_31740	COG1121	(ABC) transporter
BsBEST3145_31750	COG0803	Belongs to the bacterial solute-binding protein 9 family
BsBEST3145_31760	COG4948	Mandelate Racemase Muconate Lactonizing
BsBEST3145_31770	COG0318	PFAM AMP-dependent synthetase and ligase
BsBEST3145_31780	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BsBEST3145_31790	COG0596	Alpha beta hydrolase
BsBEST3145_31800	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BsBEST3145_31810	COG1169	isochorismate synthase
BsBEST3145_31820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BsBEST3145_31830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3145_31840	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3145_31850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BsBEST3145_31860	COG0438	transferase activity, transferring glycosyl groups
BsBEST3145_31880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3145_31890	COG0438	transferase activity, transferring glycosyl groups
BsBEST3145_31900	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3145_31910	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BsBEST3145_31920	COG0058	SHG alpha-glucan phosphorylase activity
BsBEST3145_31930	COG0297	glycogen (starch) synthase activity
BsBEST3145_31940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3145_31950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BsBEST3145_31960	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BsBEST3145_31970	COG3859	Proton-coupled thiamine transporter YuaJ
BsBEST3145_31980	COG1247	-acetyltransferase
BsBEST3145_31990	COG2268	Band 7 protein
BsBEST3145_32000	COG1585	Membrane protein implicated in regulation of membrane protease activity
BsBEST3145_32010	COG2318	DinB family
BsBEST3145_32030	COG1454	alcohol dehydrogenase
BsBEST3145_32040	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_32050	COG1510	regulation of RNA biosynthetic process
BsBEST3145_32070	COG0569	domain protein
BsBEST3145_32080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BsBEST3145_32090	COG4682	membrane
BsBEST3145_32100	COG1705	Flagellar rod assembly protein muramidase FlgJ
BsBEST3145_32110	COG0477	Major facilitator Superfamily
BsBEST3145_32120	COG5553	Cysteine dioxygenase type I
BsBEST3145_32130	COG1968	undecaprenyl-diphosphatase activity
BsBEST3145_32140	COG0628	permease
BsBEST3145_32150	COG0673	inositol 2-dehydrogenase activity
BsBEST3145_32160	COG4806	L-rhamnose isomerase
BsBEST3145_32170	COG3254	rhamnose metabolic process
BsBEST3145_32180	COG1070	Carbohydrate kinase
BsBEST3145_32190	COG1349	DNA-binding transcription factor activity
BsBEST3145_32200	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_32200	COG3347	Dehydrogenase
BsBEST3145_32210	COG0840	transmembrane signaling receptor activity
BsBEST3145_32220	COG0840	transmembrane signaling receptor activity
BsBEST3145_32240	COG0840	transmembrane signaling receptor activity
BsBEST3145_32250	COG0840	transmembrane signaling receptor activity
BsBEST3145_32280	COG0432	Pfam Uncharacterised protein family UPF0047
BsBEST3145_32290	COG0366	Alpha amylase catalytic
BsBEST3145_32300	COG1253	flavin adenine dinucleotide binding
BsBEST3145_32310	COG2738	Putative neutral zinc metallopeptidase
BsBEST3145_32340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BsBEST3145_32370	COG0166	Belongs to the GPI family
BsBEST3145_32380	COG1979	alcohol dehydrogenase
BsBEST3145_32390	COG1979	alcohol dehydrogenase
BsBEST3145_32400	COG2155	Conserved Protein
BsBEST3145_32410	COG1098	S1 RNA binding domain
BsBEST3145_32420	COG0436	Aminotransferase
BsBEST3145_32430	COG1522	sequence-specific DNA binding
BsBEST3145_32440	COG2267	carboxylic ester hydrolase activity
BsBEST3145_32460	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BsBEST3145_32470	COG2205	protein histidine kinase activity
BsBEST3145_32490	COG5018	Exonuclease
BsBEST3145_32510	COG2814	Major facilitator Superfamily
BsBEST3145_32520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3145_32530	COG3011	Protein conserved in bacteria
BsBEST3145_32550	COG3290	protein histidine kinase activity
BsBEST3145_32560	COG4565	transcriptional regulatory protein
BsBEST3145_32570	COG1744	ABC transporter substrate-binding protein PnrA-like
BsBEST3145_32580	COG3845	ABC transporter
BsBEST3145_32590	COG4603	Belongs to the binding-protein-dependent transport system permease family
BsBEST3145_32600	COG1079	Belongs to the binding-protein-dependent transport system permease family
BsBEST3145_32610	COG3493	citrate carrier protein
BsBEST3145_32630	COG2111	Na H antiporter
BsBEST3145_32630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BsBEST3145_32640	COG2111	Na H antiporter
BsBEST3145_32650	COG1006	Multisubunit Na H antiporter MnhC subunit
BsBEST3145_32660	COG0651	ATP synthesis coupled electron transport
BsBEST3145_32670	COG1863	multisubunit Na H antiporter MnhE subunit
BsBEST3145_32680	COG2212	antiporter activity
BsBEST3145_32690	COG1320	monovalent cation:proton antiporter activity
BsBEST3145_32700	COG2050	protein possibly involved in aromatic compounds catabolism
BsBEST3145_32710	COG2197	response regulator
BsBEST3145_32720	COG4585	Histidine kinase
BsBEST3145_32740	COG0142	geranyltranstransferase activity
BsBEST3145_32770	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BsBEST3145_32780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BsBEST3145_32790	COG1335	isochorismatase
BsBEST3145_32800	COG5506	Protein of unknown function (DUF1694)
BsBEST3145_32830	COG0628	permease
BsBEST3145_32850	COG1418	mRNA catabolic process
BsBEST3145_32860	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_32880	COG1511	domain protein
BsBEST3145_32890	COG1674	ftsk spoiiie
BsBEST3145_32890	COG0433	COG0433 Predicted ATPase
BsBEST3145_32900	COG4499	WXG100 protein secretion system (Wss), protein YukC
BsBEST3145_32910	COG5417	Belongs to the EsaB family
BsBEST3145_32920	COG4842	Belongs to the WXG100 family
BsBEST3145_32930	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BsBEST3145_32930	COG2508	Transcriptional regulator
BsBEST3145_32940	COG0686	Belongs to the AlaDH PNT family
BsBEST3145_32950	COG5634	Uncharacterized conserved protein (DUF2278)
BsBEST3145_32960	COG3251	PFAM MbtH domain protein
BsBEST3145_32970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_32980	COG3433	isochorismatase activity
BsBEST3145_32980	COG1535	isochorismatase
BsBEST3145_32990	COG1021	2,3-dihydroxybenzoate-AMP ligase
BsBEST3145_33000	COG1169	isochorismate synthase
BsBEST3145_33010	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_33020	COG2819	hydrolase of the alpha beta superfamily
BsBEST3145_33030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BsBEST3145_33040	COG1268	BioY protein
BsBEST3145_33050	COG2056	Na+-H+ antiporter family
BsBEST3145_33060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BsBEST3145_33070	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BsBEST3145_33080	COG3584	3D domain protein
BsBEST3145_33100	COG1252	NADH dehydrogenase
BsBEST3145_33110	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3145_33130	COG0516	GMP reductase activity
BsBEST3145_33140	COG2808	Putative FMN-binding domain
BsBEST3145_33150	COG0456	acetyltransferase
BsBEST3145_33160	COG0316	Belongs to the HesB IscA family
BsBEST3145_33170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BsBEST3145_33180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3145_33190	COG4844	belongs to the
BsBEST3145_33200	COG1252	NADH dehydrogenase
BsBEST3145_33210	COG4837	Protein of unknown function (DUF1462)
BsBEST3145_33220	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BsBEST3145_33230	COG0823	Involved in the tonB-independent uptake of proteins
BsBEST3145_33230	COG1506	peptidase
BsBEST3145_33230	COG4946	Tricorn protease homolog
BsBEST3145_33240	COG0083	homoserine kinase activity
BsBEST3145_33250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BsBEST3145_33260	COG0460	homoserine dehydrogenase
BsBEST3145_33270	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BsBEST3145_33280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BsBEST3145_33290	COG0647	UMP catabolic process
BsBEST3145_33300	COG2445	Protein of unknown function DUF86
BsBEST3145_33310	COG4470	Protein conserved in bacteria
BsBEST3145_33330	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BsBEST3145_33340	COG0739	heme binding
BsBEST3145_33360	COG3377	Domain of unknown function (DUF1805)
BsBEST3145_33370	COG0737	Belongs to the 5'-nucleotidase family
BsBEST3145_33380	COG0730	response to heat
BsBEST3145_33390	COG1801	Protein of unknown function DUF72
BsBEST3145_33410	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BsBEST3145_33420	COG2508	Transcriptional regulator
BsBEST3145_33430	COG2233	PERMEase
BsBEST3145_33440	COG2233	PERMEase
BsBEST3145_33450	COG3648	Uricase
BsBEST3145_33450	COG3195	allantoin biosynthetic process
BsBEST3145_33460	COG2351	hydroxyisourate hydrolase activity
BsBEST3145_33480	COG2080	2 iron, 2 sulfur cluster binding
BsBEST3145_33490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BsBEST3145_33500	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BsBEST3145_33510	COG2068	MobA-Related Protein
BsBEST3145_33520	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BsBEST3145_33530	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BsBEST3145_33540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BsBEST3145_33550	COG2356	endonuclease I
BsBEST3145_33560	COG3842	ATPase activity
BsBEST3145_33570	COG2188	Transcriptional regulator
BsBEST3145_33580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3145_33590	COG0395	ABC-type sugar transport system, permease component
BsBEST3145_33600	COG1175	transmembrane transport
BsBEST3145_33610	COG1653	transport
BsBEST3145_33620	COG2222	sugar isomerase
BsBEST3145_33630	COG0322	excinuclease ABC activity
BsBEST3145_33640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BsBEST3145_33670	COG0346	lactoylglutathione lyase activity
BsBEST3145_33680	COG0640	Transcriptional regulator
BsBEST3145_33690	COG0719	Fe-S assembly protein
BsBEST3145_33700	COG0822	iron-sulfur transferase activity
BsBEST3145_33710	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BsBEST3145_33720	COG0719	Fe-S assembly protein
BsBEST3145_33730	COG0396	ATPase activity
BsBEST3145_33750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BsBEST3145_33760	COG1464	Belongs to the NlpA lipoprotein family
BsBEST3145_33770	COG2011	ABC-type metal ion transport system permease component
BsBEST3145_33780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BsBEST3145_33800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BsBEST3145_33810	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BsBEST3145_33830	COG0509	glycine decarboxylation via glycine cleavage system
BsBEST3145_33840	COG1393	Belongs to the ArsC family
BsBEST3145_33850	COG1960	acyl-CoA dehydrogenase activity
BsBEST3145_33860	COG0183	Belongs to the thiolase family
BsBEST3145_33870	COG1024	Enoyl-CoA hydratase
BsBEST3145_33870	COG1250	3-hydroxyacyl-CoA dehydrogenase
BsBEST3145_33890	COG0506	proline dehydrogenase activity
BsBEST3145_33910	COG5577	PFAM Coat F domain
BsBEST3145_33920	COG1846	Transcriptional regulator
BsBEST3145_33930	COG0477	Major facilitator Superfamily
BsBEST3145_33940	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3145_33950	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_33960	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_33970	COG0583	DNA-binding transcription factor activity
BsBEST3145_33990	COG1120	ATPase activity
BsBEST3145_34030	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_34040	COG0783	Belongs to the Dps family
BsBEST3145_34050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3145_34060	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_34070	COG2770	Histidine kinase
BsBEST3145_34070	COG2205	protein histidine kinase activity
BsBEST3145_34090	COG1309	transcriptional regulator
BsBEST3145_34100	COG0114	fumarate hydratase activity
BsBEST3145_34120	COG0697	spore germination
BsBEST3145_34130	COG0814	amino acid
BsBEST3145_34150	COG2197	response regulator
BsBEST3145_34160	COG4585	Histidine kinase
BsBEST3145_34170	COG4758	membrane
BsBEST3145_34180	COG3595	metallopeptidase activity
BsBEST3145_34190	COG1842	Phage shock protein A
BsBEST3145_34200	COG4758	membrane
BsBEST3145_34210	COG2814	Major facilitator Superfamily
BsBEST3145_34220	COG2096	Adenosyltransferase
BsBEST3145_34230	COG1120	ATPase activity
BsBEST3145_34240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3145_34250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3145_34260	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_34270	COG3386	PFAM SMP-30 Gluconolaconase
BsBEST3145_34280	COG2205	protein histidine kinase activity
BsBEST3145_34290	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_34310	COG1191	sigma factor activity
BsBEST3145_34330	COG2140	Oxalate decarboxylase
BsBEST3145_34350	COG0577	efflux transmembrane transporter activity
BsBEST3145_34360	COG1136	(ABC) transporter
BsBEST3145_34370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BsBEST3145_34380	COG1120	ATPase activity
BsBEST3145_34390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3145_34400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BsBEST3145_34410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3145_34420	COG0531	amino acid
BsBEST3145_34440	COG1988	membrane-bound metal-dependent
BsBEST3145_34450	COG1368	sulfuric ester hydrolase activity
BsBEST3145_34460	COG1910	domain protein
BsBEST3145_34470	COG0725	ABC transporter, periplasmic molybdate-binding protein
BsBEST3145_34480	COG4149	molybdate abc transporter
BsBEST3145_34490	COG0656	L-ascorbic acid biosynthetic process
BsBEST3145_34510	COG0025	NhaP-type Na H and K H
BsBEST3145_34520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BsBEST3145_34530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BsBEST3145_34540	COG3973	AAA domain
BsBEST3145_34550	COG2860	membrane
BsBEST3145_34560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BsBEST3145_34570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BsBEST3145_34580	COG2217	Heavy metal translocating P-type atpase
BsBEST3145_34590	COG2217	Heavy metal translocating P-type atpase
BsBEST3145_34600	COG2608	mercury ion transmembrane transporter activity
BsBEST3145_34610	COG1937	Protein conserved in bacteria
BsBEST3145_34620	COG0673	inositol 2-dehydrogenase activity
BsBEST3145_34630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BsBEST3145_34640	COG1289	transmembrane transporter activity
BsBEST3145_34660	COG2076	Multidrug Resistance protein
BsBEST3145_34670	COG1309	transcriptional regulator
BsBEST3145_34680	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_34690	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BsBEST3145_34700	COG0557	exoribonuclease II activity
BsBEST3145_34710	COG1647	Serine aminopeptidase, S33
BsBEST3145_34720	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BsBEST3145_34730	COG0596	Alpha beta hydrolase
BsBEST3145_34740	COG1476	TRANSCRIPTIONal
BsBEST3145_34750	COG1396	sequence-specific DNA binding
BsBEST3145_34760	COG1396	sequence-specific DNA binding
BsBEST3145_34770	COG1733	regulation of RNA biosynthetic process
BsBEST3145_34780	COG0840	transmembrane signaling receptor activity
BsBEST3145_34790	COG1174	glycine betaine transport
BsBEST3145_34800	COG1732	Glycine betaine
BsBEST3145_34810	COG1174	glycine betaine transport
BsBEST3145_34820	COG0517	IMP dehydrogenase activity
BsBEST3145_34820	COG1125	glycine betaine transport
BsBEST3145_34830	COG1510	regulation of RNA biosynthetic process
BsBEST3145_34870	COG5658	integral membrane protein
BsBEST3145_34880	COG0640	Transcriptional regulator
BsBEST3145_34890	COG1174	glycine betaine transport
BsBEST3145_34900	COG1732	Glycine betaine
BsBEST3145_34910	COG1174	glycine betaine transport
BsBEST3145_34920	COG0517	IMP dehydrogenase activity
BsBEST3145_34920	COG1125	glycine betaine transport
BsBEST3145_34930	COG1510	regulation of RNA biosynthetic process
BsBEST3145_34940	COG2095	MarC family integral membrane protein
BsBEST3145_34960	COG3064	Membrane
BsBEST3145_34970	COG4640	response to antibiotic
BsBEST3145_34980	COG0456	acetyltransferase
BsBEST3145_34990	COG0148	phosphopyruvate hydratase activity
BsBEST3145_35000	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BsBEST3145_35010	COG0149	triose-phosphate isomerase activity
BsBEST3145_35020	COG0126	phosphoglycerate kinase activity
BsBEST3145_35030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3145_35040	COG2390	Transcriptional regulator
BsBEST3145_35050	COG2814	Major facilitator Superfamily
BsBEST3145_35060	COG1609	Transcriptional regulator
BsBEST3145_35070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_35080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_35090	COG0583	DNA-binding transcription factor activity
BsBEST3145_35110	COG0697	spore germination
BsBEST3145_35120	COG1113	amino acid transport
BsBEST3145_35130	COG1113	amino acid transport
BsBEST3145_35140	COG1113	amino acid transport
BsBEST3145_35150	COG3858	chitin binding
BsBEST3145_35160	COG3858	chitin binding
BsBEST3145_35170	COG1556	Lactate utilization protein
BsBEST3145_35180	COG1556	Lactate utilization protein
BsBEST3145_35190	COG1139	Iron-sulfur cluster binding protein
BsBEST3145_35200	COG0247	lactate metabolic process
BsBEST3145_35210	COG0247	lactate metabolic process
BsBEST3145_35220	COG4640	response to antibiotic
BsBEST3145_35230	COG4640	response to antibiotic
BsBEST3145_35240	COG4640	response to antibiotic
BsBEST3145_35250	COG0456	acetyltransferase
BsBEST3145_35260	COG0148	phosphopyruvate hydratase activity
BsBEST3145_35270	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BsBEST3145_35280	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BsBEST3145_35290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BsBEST3145_35300	COG0149	triose-phosphate isomerase activity
BsBEST3145_35310	COG0149	triose-phosphate isomerase activity
BsBEST3145_35320	COG0126	phosphoglycerate kinase activity
BsBEST3145_35330	COG0126	phosphoglycerate kinase activity
BsBEST3145_35340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BsBEST3145_35350	COG2390	Transcriptional regulator
BsBEST3145_35360	COG2814	Major facilitator Superfamily
BsBEST3145_35370	COG1609	Transcriptional regulator
BsBEST3145_35380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_35390	COG0583	DNA-binding transcription factor activity
BsBEST3145_35400	COG0697	spore germination
BsBEST3145_35410	COG1113	amino acid transport
BsBEST3145_35420	COG3858	chitin binding
BsBEST3145_35430	COG1556	Lactate utilization protein
BsBEST3145_35440	COG1139	Iron-sulfur cluster binding protein
BsBEST3145_35450	COG0247	lactate metabolic process
BsBEST3145_35460	COG2197	response regulator
BsBEST3145_35470	COG4585	Histidine kinase
BsBEST3145_35480	COG0842	Transport permease protein
BsBEST3145_35490	COG1131	(ABC) transporter
BsBEST3145_35500	COG0596	Alpha beta hydrolase
BsBEST3145_35510	COG2208	phosphoserine phosphatase activity
BsBEST3145_35520	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BsBEST3145_35530	COG1874	Beta-galactosidase
BsBEST3145_35540	COG3833	ABC-type maltose transport systems, permease component
BsBEST3145_35550	COG1175	transmembrane transport
BsBEST3145_35560	COG2182	Extracellular solute-binding protein
BsBEST3145_35570	COG1609	Transcriptional regulator
BsBEST3145_35580	COG2186	Transcriptional regulator
BsBEST3145_35590	COG1620	l-lactate permease
BsBEST3145_35600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BsBEST3145_35620	COG5039	Polysaccharide pyruvyl transferase
BsBEST3145_35630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3145_35640	COG0110	maltose O-acetyltransferase activity
BsBEST3145_35650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BsBEST3145_35660	COG2244	polysaccharide biosynthetic process
BsBEST3145_35670	COG1216	Glycosyl transferase, family 2
BsBEST3145_35680	COG5039	Polysaccharide pyruvyl transferase
BsBEST3145_35690	COG1216	Glycosyl transferase, family 2
BsBEST3145_35710	COG0438	transferase activity, transferring glycosyl groups
BsBEST3145_35720	COG1215	transferase activity, transferring glycosyl groups
BsBEST3145_35730	COG0438	transferase activity, transferring glycosyl groups
BsBEST3145_35740	COG1086	Polysaccharide biosynthesis protein
BsBEST3145_35750	COG0489	protein tyrosine kinase activity
BsBEST3145_35760	COG3944	biosynthesis protein
BsBEST3145_35770	COG1396	sequence-specific DNA binding
BsBEST3145_35780	COG2272	Belongs to the type-B carboxylesterase lipase family
BsBEST3145_35800	COG3479	Phenolic acid decarboxylase
BsBEST3145_35830	COG1794	racemase activity, acting on amino acids and derivatives
BsBEST3145_35840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BsBEST3145_35850	COG1621	beta-fructofuranosidase activity
BsBEST3145_35860	COG1621	beta-fructofuranosidase activity
BsBEST3145_35870	COG0531	amino acid
BsBEST3145_35880	COG1309	transcriptional regulator
BsBEST3145_35890	COG2076	Multidrug Resistance protein
BsBEST3145_35900	COG2076	Multidrug Resistance protein
BsBEST3145_35920	COG0277	FAD linked oxidase domain protein
BsBEST3145_35930	COG3621	Patatin-like phospholipase
BsBEST3145_35940	COG0740	serine-type endopeptidase activity
BsBEST3145_35950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BsBEST3145_35960	COG0366	Alpha amylase catalytic
BsBEST3145_35970	COG1554	hydrolase, family 65, central catalytic
BsBEST3145_35980	COG5521	maltodextrose utilization protein MalA
BsBEST3145_35990	COG3833	ABC-type maltose transport systems, permease component
BsBEST3145_36000	COG1175	transmembrane transport
BsBEST3145_36010	COG2182	Extracellular solute-binding protein
BsBEST3145_36030	COG1609	Transcriptional regulator
BsBEST3145_36040	COG1611	Belongs to the LOG family
BsBEST3145_36050	COG1694	Mazg nucleotide pyrophosphohydrolase
BsBEST3145_36060	COG0659	secondary active sulfate transmembrane transporter activity
BsBEST3145_36070	COG0288	reversible hydration of carbon dioxide
BsBEST3145_36080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BsBEST3145_36090	COG0577	efflux transmembrane transporter activity
BsBEST3145_36100	COG1136	(ABC) transporter
BsBEST3145_36110	COG5002	protein histidine kinase activity
BsBEST3145_36120	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_36140	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BsBEST3145_36150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3145_36160	COG1481	regulation of sporulation
BsBEST3145_36170	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BsBEST3145_36180	COG1660	Displays ATPase and GTPase activities
BsBEST3145_36190	COG1051	belongs to the nudix hydrolase family
BsBEST3145_36200	COG0492	ferredoxin-NADP+ reductase activity
BsBEST3145_36210	COG0791	NLP P60 protein
BsBEST3145_36210	COG3883	PFAM NLP P60 protein
BsBEST3145_36220	COG0457	Tetratricopeptide repeat
BsBEST3145_36230	COG1132	(ABC) transporter
BsBEST3145_36270	COG0140	phosphoribosyl-ATP diphosphatase activity
BsBEST3145_36270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BsBEST3145_36280	COG0107	imidazoleglycerol-phosphate synthase activity
BsBEST3145_36290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BsBEST3145_36300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BsBEST3145_36310	COG0131	Imidazoleglycerol-phosphate dehydratase
BsBEST3145_36320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BsBEST3145_36330	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BsBEST3145_36340	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BsBEST3145_36350	COG4990	cell redox homeostasis
BsBEST3145_36360	COG5297	Belongs to the glycosyl hydrolase family 6
BsBEST3145_36370	COG0110	maltose O-acetyltransferase activity
BsBEST3145_36380	COG0546	phosphoglycolate phosphatase activity
BsBEST3145_36390	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BsBEST3145_36400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BsBEST3145_36410	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BsBEST3145_36420	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BsBEST3145_36430	COG0363	glucosamine-6-phosphate deaminase activity
BsBEST3145_36440	COG2188	Transcriptional regulator
BsBEST3145_36450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3145_36460	COG1846	Transcriptional regulator
BsBEST3145_36470	COG2124	cytochrome p450
BsBEST3145_36490	COG1846	Transcriptional regulator
BsBEST3145_36500	COG2814	Major facilitator Superfamily
BsBEST3145_36510	COG1950	PFAM Membrane protein of
BsBEST3145_36520	COG1983	PspC domain protein
BsBEST3145_36530	COG3595	metallopeptidase activity
BsBEST3145_36560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3145_36570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BsBEST3145_36580	COG0556	nucleotide-excision repair
BsBEST3145_36590	COG4897	Protein conserved in bacteria
BsBEST3145_36600	COG0574	Belongs to the PEP-utilizing enzyme family
BsBEST3145_36600	COG3848	Pyruvate phosphate dikinase
BsBEST3145_36610	COG1309	transcriptional regulator
BsBEST3145_36620	COG2814	Major facilitator Superfamily
BsBEST3145_36630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3145_36650	COG0793	Belongs to the peptidase S41A family
BsBEST3145_36650	COG3409	Peptidoglycan-binding domain 1 protein
BsBEST3145_36660	COG2177	Part of the ABC transporter FtsEX involved in
BsBEST3145_36670	COG2884	Cell division ATP-binding protein ftsE
BsBEST3145_36680	COG2010	Cytochrome c
BsBEST3145_36690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3145_36700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BsBEST3145_36710	COG0653	protein targeting
BsBEST3145_36720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BsBEST3145_36740	COG1516	flagellar protein fliS
BsBEST3145_36750	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BsBEST3145_36760	COG1334	flagellar protein FlaG
BsBEST3145_36770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3145_36780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BsBEST3145_36790	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BsBEST3145_36810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BsBEST3145_36820	COG4786	Flagellar basal body rod
BsBEST3145_36820	COG1256	bacterial-type flagellum assembly
BsBEST3145_36830	COG3418	PFAM FlgN family protein
BsBEST3145_36840	COG2747	anti-sigma28 factor FlgM
BsBEST3145_36860	COG1040	competence protein
BsBEST3145_36880	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BsBEST3145_36890	COG1307	EDD domain protein, DegV family
BsBEST3145_36900	COG2197	response regulator
BsBEST3145_36910	COG4585	Histidine kinase
BsBEST3145_36920	COG1739	Uncharacterized protein family UPF0029
BsBEST3145_36930	COG1316	TRANSCRIPTIONal
BsBEST3145_36940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BsBEST3145_36950	COG0438	transferase activity, transferring glycosyl groups
BsBEST3145_36960	COG1215	transferase activity, transferring glycosyl groups
BsBEST3145_36970	COG3206	protein involved in exopolysaccharide biosynthesis
BsBEST3145_36980	COG3307	-O-antigen
BsBEST3145_36990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3145_37000	COG0438	transferase activity, transferring glycosyl groups
BsBEST3145_37000	COG0297	glycogen (starch) synthase activity
BsBEST3145_37010	COG2244	polysaccharide biosynthetic process
BsBEST3145_37040	COG0860	N-Acetylmuramoyl-L-alanine amidase
BsBEST3145_37040	COG2247	cell wall binding repeat
BsBEST3145_37050	COG2247	cell wall binding repeat
BsBEST3145_37050	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3145_37070	COG1316	TRANSCRIPTIONal
BsBEST3145_37080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BsBEST3145_37090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3145_37100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3145_37100	COG1215	transferase activity, transferring glycosyl groups
BsBEST3145_37110	COG0463	Glycosyl transferase, family 2
BsBEST3145_37130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BsBEST3145_37140	COG1134	teichoic acid transport
BsBEST3145_37150	COG1682	transport, permease protein
BsBEST3145_37160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3145_37170	COG0438	transferase activity, transferring glycosyl groups
BsBEST3145_37180	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BsBEST3145_37190	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BsBEST3145_37200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3145_37220	COG4193	domain, Protein
BsBEST3145_37230	COG1482	cell wall glycoprotein biosynthetic process
BsBEST3145_37240	COG0697	spore germination
BsBEST3145_37250	COG0814	amino acid
BsBEST3145_37270	COG2814	Major facilitator Superfamily
BsBEST3145_37280	COG1316	TRANSCRIPTIONal
BsBEST3145_37290	COG0561	phosphatase activity
BsBEST3145_37300	COG0791	NLP P60 protein
BsBEST3145_37320	COG2843	Capsule synthesis protein
BsBEST3145_37340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BsBEST3145_37350	COG1609	Transcriptional regulator
BsBEST3145_37360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3145_37370	COG1869	D-ribose catabolic process
BsBEST3145_37380	COG1129	ABC transporter
BsBEST3145_37390	COG1172	Belongs to the binding-protein-dependent transport system permease family
BsBEST3145_37400	COG1879	ABC-type sugar transport system periplasmic component
BsBEST3145_37410	COG3103	Sh3 type 3 domain protein
BsBEST3145_37430	COG2249	NAD(P)H dehydrogenase (quinone) activity
BsBEST3145_37440	COG3527	Alpha-acetolactate decarboxylase
BsBEST3145_37450	COG0028	Belongs to the TPP enzyme family
BsBEST3145_37460	COG0583	DNA-binding transcription factor activity
BsBEST3145_37470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BsBEST3145_37500	COG5337	Spore coat protein CotH
BsBEST3145_37520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BsBEST3145_37540	COG0405	Gamma-glutamyltransferase
BsBEST3145_37550	COG1522	sequence-specific DNA binding
BsBEST3145_37560	COG2059	Chromate
BsBEST3145_37570	COG2059	Chromate
BsBEST3145_37590	COG0655	NAD(P)H dehydrogenase (quinone) activity
BsBEST3145_37600	COG0583	DNA-binding transcription factor activity
BsBEST3145_37610	COG1515	deoxyribonuclease V activity
BsBEST3145_37620	COG2849	repeat protein
BsBEST3145_37630	COG5444	nuclease activity
BsBEST3145_37660	COG3878	Protein conserved in bacteria
BsBEST3145_37670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BsBEST3145_37680	COG4464	protein tyrosine phosphatase activity
BsBEST3145_37690	COG0489	protein tyrosine kinase activity
BsBEST3145_37700	COG3944	biosynthesis protein
BsBEST3145_37720	COG4715	Zinc finger, swim domain protein
BsBEST3145_37730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BsBEST3145_37740	COG0561	phosphatase activity
BsBEST3145_37750	COG1349	DNA-binding transcription factor activity
BsBEST3145_37760	COG0629	single-stranded DNA binding
BsBEST3145_37790	COG3764	Sortase (surface protein transpeptidase)
BsBEST3145_37810	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_37810	COG2972	Histidine kinase
BsBEST3145_37820	COG1970	mechanosensitive ion channel activity
BsBEST3145_37830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BsBEST3145_37840	COG0457	Tetratricopeptide repeat
BsBEST3145_37850	COG4786	Flagellar basal body rod
BsBEST3145_37860	COG4786	Flagellar basal body rod
BsBEST3145_37870	COG1077	Cell shape determining protein MreB Mrl
BsBEST3145_37880	COG1609	Transcriptional regulator
BsBEST3145_37890	COG1846	Transcriptional regulator
BsBEST3145_37900	COG2814	Major facilitator Superfamily
BsBEST3145_37910	COG3420	alginic acid biosynthetic process
BsBEST3145_37920	COG1953	Uracil, thiamine, allantoin
BsBEST3145_37930	COG0477	Major facilitator Superfamily
BsBEST3145_37940	COG1335	isochorismatase
BsBEST3145_37960	COG0004	ammonium transporteR
BsBEST3145_37970	COG0347	Belongs to the P(II) protein family
BsBEST3145_37980	COG0671	phosphoesterase, PA-phosphatase related
BsBEST3145_38000	COG0739	heme binding
BsBEST3145_38010	COG1247	-acetyltransferase
BsBEST3145_38030	COG2089	acid synthase
BsBEST3145_38050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3145_38060	COG0789	Transcriptional regulator
BsBEST3145_38080	COG2910	NAD(P)H-binding
BsBEST3145_38090	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3145_38100	COG0804	urea catabolic process
BsBEST3145_38110	COG0832	Belongs to the urease beta subunit family
BsBEST3145_38120	COG0831	urea catabolic process
BsBEST3145_38140	COG3237	CsbD-like
BsBEST3145_38150	COG1994	Peptidase M50
BsBEST3145_38160	COG0457	Tetratricopeptide repeat
BsBEST3145_38170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BsBEST3145_38180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BsBEST3145_38200	COG2304	oxidoreductase activity
BsBEST3145_38210	COG2304	oxidoreductase activity
BsBEST3145_38230	COG2385	sporulation resulting in formation of a cellular spore
BsBEST3145_38240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3145_38260	COG4836	Membrane
BsBEST3145_38280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BsBEST3145_38290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BsBEST3145_38300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BsBEST3145_38310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BsBEST3145_38320	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BsBEST3145_38330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BsBEST3145_38350	COG0356	it plays a direct role in the translocation of protons across the membrane
BsBEST3145_38370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BsBEST3145_38380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BsBEST3145_38390	COG4475	Protein of unknown function (DUF436)
BsBEST3145_38400	COG0698	ribose 5-phosphate isomerase
BsBEST3145_38410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BsBEST3145_38420	COG1971	Probably functions as a manganese efflux pump
BsBEST3145_38430	COG0009	L-threonylcarbamoyladenylate synthase
BsBEST3145_38440	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BsBEST3145_38480	COG2890	protein-(glutamine-N5) methyltransferase activity
BsBEST3145_38490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BsBEST3145_38500	COG0346	lactoylglutathione lyase activity
BsBEST3145_38510	COG0789	Transcriptional regulator
BsBEST3145_38520	COG0679	Auxin Efflux Carrier
BsBEST3145_38530	COG0281	malic enzyme
BsBEST3145_38540	COG1435	thymidine kinase activity
BsBEST3145_38560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BsBEST3145_38570	COG1494	fructose-1,6-bisphosphatase
BsBEST3145_38580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BsBEST3145_38590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BsBEST3145_38600	COG0191	fructose-bisphosphate aldolase activity
BsBEST3145_38610	COG2204	response regulator
BsBEST3145_38620	COG4821	SIS domain
BsBEST3145_38630	COG0504	CTP synthase activity
BsBEST3145_38640	COG3343	RNA polymerase activity
BsBEST3145_38650	COG1960	acyl-CoA dehydrogenase activity
BsBEST3145_38660	COG0247	lactate metabolic process
BsBEST3145_38660	COG2181	nitrate reductase activity
BsBEST3145_38670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3145_38680	COG4294	response to UV
BsBEST3145_38700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3145_38710	COG1132	(ABC) transporter
BsBEST3145_38720	COG1132	(ABC) transporter
BsBEST3145_38730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BsBEST3145_38750	COG2181	nitrate reductase activity
BsBEST3145_38760	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BsBEST3145_38770	COG1140	nitrate reductase beta subunit
BsBEST3145_38780	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BsBEST3145_38790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3145_38810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BsBEST3145_38820	COG2223	nitrite transmembrane transporter activity
BsBEST3145_38830	COG0018	arginyl-trna synthetase
BsBEST3145_38840	COG4506	Protein conserved in bacteria
BsBEST3145_38860	COG0535	radical SAM domain protein
BsBEST3145_38880	COG1131	(ABC) transporter
BsBEST3145_38890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BsBEST3145_38900	COG0612	Peptidase, M16
BsBEST3145_38910	COG0612	Peptidase, M16
BsBEST3145_38930	COG3391	amine dehydrogenase activity
BsBEST3145_38940	COG3391	amine dehydrogenase activity
BsBEST3145_38950	COG0457	Tetratricopeptide repeat
BsBEST3145_38970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BsBEST3145_38980	COG0010	Belongs to the arginase family
BsBEST3145_38990	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BsBEST3145_39000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BsBEST3145_39020	COG1994	Peptidase M50
BsBEST3145_39030	COG1942	4-Oxalocrotonate Tautomerase
BsBEST3145_39040	COG1846	Transcriptional regulator
BsBEST3145_39050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BsBEST3145_39060	COG0477	Major facilitator Superfamily
BsBEST3145_39070	COG1959	2 iron, 2 sulfur cluster binding
BsBEST3145_39080	COG3465	dGTPase activity
BsBEST3145_39090	COG1078	dGTPase activity
BsBEST3145_39100	COG4844	belongs to the
BsBEST3145_39120	COG0697	spore germination
BsBEST3145_39130	COG0095	Lipoate-protein ligase
BsBEST3145_39140	COG0583	DNA-binding transcription factor activity
BsBEST3145_39150	COG0280	phosphate acetyltransferase
BsBEST3145_39160	COG3253	May function as heme-dependent peroxidase
BsBEST3145_39170	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_39180	COG0436	Aminotransferase
BsBEST3145_39190	COG2814	Major facilitator Superfamily
BsBEST3145_39200	COG0151	Belongs to the GarS family
BsBEST3145_39210	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_39220	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3145_39230	COG0077	Prephenate dehydratase
BsBEST3145_39240	COG2814	Major facilitator Superfamily
BsBEST3145_39250	COG0833	amino acid
BsBEST3145_39260	COG4187	Peptidase family M20/M25/M40
BsBEST3145_39270	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_39280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BsBEST3145_39300	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3145_39310	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BsBEST3145_39320	COG1091	dTDP-4-dehydrorhamnose reductase activity
BsBEST3145_39330	COG1088	dTDP-glucose 4,6-dehydratase activity
BsBEST3145_39340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BsBEST3145_39350	COG3980	spore coat polysaccharide biosynthesis protein
BsBEST3145_39360	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BsBEST3145_39370	COG2089	acid synthase
BsBEST3145_39380	COG0456	acetyltransferase
BsBEST3145_39390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BsBEST3145_39400	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BsBEST3145_39410	COG0463	Glycosyl transferase, family 2
BsBEST3145_39430	COG2363	Small membrane protein
BsBEST3145_39440	COG2233	PERMEase
BsBEST3145_39460	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_39470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BsBEST3145_39480	COG1216	Glycosyl transferase, family 2
BsBEST3145_39510	COG1695	Transcriptional regulator
BsBEST3145_39520	COG0351	phosphomethylpyrimidine kinase
BsBEST3145_39540	COG1621	beta-fructofuranosidase activity
BsBEST3145_39550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3145_39550	COG1263	PTS System
BsBEST3145_39560	COG2116	formate transmembrane transporter activity
BsBEST3145_39570	COG3711	transcriptional antiterminator
BsBEST3145_39590	COG1404	Belongs to the peptidase S8 family
BsBEST3145_39600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_39610	COG0778	Nitroreductase
BsBEST3145_39620	COG0772	Belongs to the SEDS family
BsBEST3145_39640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BsBEST3145_39650	COG1845	cytochrome c oxidase, subunit III
BsBEST3145_39660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BsBEST3145_39670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BsBEST3145_39680	COG2261	transglycosylase associated protein
BsBEST3145_39690	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BsBEST3145_39700	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BsBEST3145_39710	COG2246	polysaccharide biosynthetic process
BsBEST3145_39720	COG1309	transcriptional regulator
BsBEST3145_39740	COG3162	membrane
BsBEST3145_39750	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BsBEST3145_39760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BsBEST3145_39770	COG2837	iron assimilation
BsBEST3145_39780	COG2822	iron ion transport
BsBEST3145_39790	COG0672	)-iron permease
BsBEST3145_39800	COG0352	thiamine-phosphate diphosphorylase activity
BsBEST3145_39810	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BsBEST3145_39820	COG0583	DNA-binding transcription factor activity
BsBEST3145_39830	COG1380	Effector of murein hydrolase LrgA
BsBEST3145_39840	COG1346	cytolysis
BsBEST3145_39850	COG2814	Major facilitator Superfamily
BsBEST3145_39860	COG4895	conserved protein (DUF2196)
BsBEST3145_39870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BsBEST3145_39880	COG0346	lactoylglutathione lyase activity
BsBEST3145_39900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3145_39910	COG1404	Belongs to the peptidase S8 family
BsBEST3145_39920	COG1263	PTS System
BsBEST3145_39920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3145_39930	COG3711	transcriptional antiterminator
BsBEST3145_39940	COG1442	glycosyl transferase family 8
BsBEST3145_39950	COG5522	Integral membrane protein (intg_mem_TP0381)
BsBEST3145_39960	COG1846	Transcriptional regulator
BsBEST3145_39970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BsBEST3145_39980	COG2234	aminopeptidase activity
BsBEST3145_39990	COG2357	RelA SpoT domain protein
BsBEST3145_40010	COG2801	Transposase and inactivated derivatives
BsBEST3145_40020	COG1575	Belongs to the MenA family. Type 1 subfamily
BsBEST3145_40030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BsBEST3145_40040	COG1696	Membrane protein involved in D-alanine export
BsBEST3145_40050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BsBEST3145_40060	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BsBEST3145_40070	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3145_40080	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BsBEST3145_40090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BsBEST3145_40100	COG1486	melibiose metabolic process
BsBEST3145_40110	COG1447	Phosphotransferase system cellobiose-specific component IIA
BsBEST3145_40120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3145_40130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BsBEST3145_40140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BsBEST3145_40140	COG3711	transcriptional antiterminator
BsBEST3145_40160	COG2094	Belongs to the DNA glycosylase MPG family
BsBEST3145_40170	COG0753	catalase activity
BsBEST3145_40180	COG2814	Major facilitator Superfamily
BsBEST3145_40190	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BsBEST3145_40200	COG1131	(ABC) transporter
BsBEST3145_40240	COG1595	DNA-templated transcription, initiation
BsBEST3145_40250	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BsBEST3145_40260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BsBEST3145_40270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BsBEST3145_40280	COG4988	ABC transporter
BsBEST3145_40290	COG1294	oxidase, subunit
BsBEST3145_40300	COG1271	oxidase subunit
BsBEST3145_40310	COG3493	citrate carrier protein
BsBEST3145_40320	COG0501	Belongs to the peptidase M48B family
BsBEST3145_40340	COG0726	polysaccharide deacetylase
BsBEST3145_40350	COG3842	ATPase activity
BsBEST3145_40360	COG2508	Transcriptional regulator
BsBEST3145_40370	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_40380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BsBEST3145_40390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BsBEST3145_40410	COG4585	Histidine kinase
BsBEST3145_40420	COG2197	response regulator
BsBEST3145_40430	COG2195	Cleaves the N-terminal amino acid of tripeptides
BsBEST3145_40450	COG4894	glucomannan catabolic process
BsBEST3145_40460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3145_40470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BsBEST3145_40480	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_40490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BsBEST3145_40500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BsBEST3145_40510	COG2610	gluconate transmembrane transporter activity
BsBEST3145_40520	COG0500	methyltransferase
BsBEST3145_40530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3145_40560	COG0753	catalase activity
BsBEST3145_40560	COG0693	protein deglycase activity
BsBEST3145_40570	COG2851	Citrate transporter
BsBEST3145_40580	COG2273	Hydrolase Family 16
BsBEST3145_40590	COG3711	transcriptional antiterminator
BsBEST3145_40610	COG2270	Major facilitator Superfamily
BsBEST3145_40620	COG0513	Belongs to the DEAD box helicase family
BsBEST3145_40630	COG3401	FG-GAP repeat protein
BsBEST3145_40630	COG2755	lipolytic protein G-D-S-L family
BsBEST3145_40860	COG0697	spore germination
BsBEST3145_40890	COG0589	response to stress
BsBEST3145_40900	COG2723	6-phospho-beta-galactosidase activity
BsBEST3145_40910	COG2723	6-phospho-beta-galactosidase activity
BsBEST3145_40920	COG2190	(PTS) system
BsBEST3145_40920	COG1263	PTS System
BsBEST3145_40920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BsBEST3145_40950	COG5444	nuclease activity
BsBEST3145_40980	COG3507	Belongs to the glycosyl hydrolase 43 family
BsBEST3145_41010	COG2986	histidine ammonia-lyase
BsBEST3145_41020	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BsBEST3145_41030	COG1228	amidohydrolase
BsBEST3145_41040	COG0010	Belongs to the arginase family
BsBEST3145_41050	COG0833	amino acid
BsBEST3145_41060	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BsBEST3145_41070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BsBEST3145_41080	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BsBEST3145_41090	COG2390	Transcriptional regulator
BsBEST3145_41110	COG3192	ethanolamine utilization protein
BsBEST3145_41120	COG2079	MmgE PrpD family protein
BsBEST3145_41130	COG1473	amidohydrolase
BsBEST3145_41140	COG1126	abc transporter atp-binding protein
BsBEST3145_41150	COG0765	amino acid transport
BsBEST3145_41160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BsBEST3145_41170	COG0456	acetyltransferase
BsBEST3145_41180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BsBEST3145_41200	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BsBEST3145_41210	COG0561	phosphatase activity
BsBEST3145_41270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BsBEST3145_41280	COG5294	Protein conserved in bacteria
BsBEST3145_41290	COG0577	efflux transmembrane transporter activity
BsBEST3145_41300	COG0577	efflux transmembrane transporter activity
BsBEST3145_41310	COG1136	(ABC) transporter
BsBEST3145_41320	COG1136	(ABC) transporter
BsBEST3145_41330	COG2205	protein histidine kinase activity
BsBEST3145_41340	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_41350	COG0191	fructose-bisphosphate aldolase activity
BsBEST3145_41360	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3145_41370	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3145_41380	COG0673	inositol 2-dehydrogenase activity
BsBEST3145_41390	COG2814	Major facilitator Superfamily
BsBEST3145_41400	COG1082	Xylose isomerase domain protein TIM barrel
BsBEST3145_41410	COG3962	Belongs to the TPP enzyme family
BsBEST3145_41420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BsBEST3145_41440	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_41450	COG1349	DNA-binding transcription factor activity
BsBEST3145_41460	COG0667	Aldo Keto reductase
BsBEST3145_41490	COG2814	Major facilitator Superfamily
BsBEST3145_41500	COG0326	Molecular chaperone. Has ATPase activity
BsBEST3145_41520	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_41530	COG1309	transcriptional regulator
BsBEST3145_41540	COG1012	belongs to the aldehyde dehydrogenase family
BsBEST3145_41550	COG0456	acetyltransferase
BsBEST3145_41560	COG2850	peptidyl-arginine hydroxylation
BsBEST3145_41570	COG2226	methyltransferase
BsBEST3145_41600	COG0367	asparagine synthase
BsBEST3145_41610	COG2814	Major facilitator Superfamily
BsBEST3145_41620	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BsBEST3145_41640	COG1714	RDD family
BsBEST3145_41650	COG2311	Membrane
BsBEST3145_41660	COG1917	Cupin 2, conserved barrel domain protein
BsBEST3145_41670	COG1309	transcriptional regulator
BsBEST3145_41680	COG1028	Short-chain dehydrogenase reductase Sdr
BsBEST3145_41690	COG1846	Transcriptional regulator
BsBEST3145_41700	COG1380	Effector of murein hydrolase LrgA
BsBEST3145_41710	COG1346	cytolysis
BsBEST3145_41720	COG5039	Polysaccharide pyruvyl transferase
BsBEST3145_41730	COG1929	Belongs to the glycerate kinase type-1 family
BsBEST3145_41740	COG1802	Transcriptional regulator
BsBEST3145_41750	COG1070	Carbohydrate kinase
BsBEST3145_41760	COG2610	gluconate transmembrane transporter activity
BsBEST3145_41770	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BsBEST3145_41780	COG0450	alkyl hydroperoxide reductase
BsBEST3145_41790	COG3634	alkyl hydroperoxide reductase activity
BsBEST3145_41800	COG2723	6-phospho-beta-galactosidase activity
BsBEST3145_41810	COG2190	(PTS) system
BsBEST3145_41820	COG2188	Transcriptional regulator
BsBEST3145_41850	COG1131	(ABC) transporter
BsBEST3145_41860	COG1994	Peptidase M50
BsBEST3145_41870	COG0535	radical SAM domain protein
BsBEST3145_41890	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BsBEST3145_41900	COG5293	efflux transmembrane transporter activity
BsBEST3145_41920	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BsBEST3145_41930	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BsBEST3145_41960	COG1063	alcohol dehydrogenase
BsBEST3145_42000	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BsBEST3145_42010	COG0456	acetyltransferase
BsBEST3145_42020	COG0457	Tetratricopeptide repeat
BsBEST3145_42030	COG0010	Belongs to the arginase family
BsBEST3145_42040	COG0833	amino acid
BsBEST3145_42050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BsBEST3145_42060	COG3829	transcription factor binding
BsBEST3145_42070	COG5002	protein histidine kinase activity
BsBEST3145_42090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BsBEST3145_42100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BsBEST3145_42110	COG4853	Protein conserved in bacteria
BsBEST3145_42120	COG4863	YycH protein
BsBEST3145_42130	COG5002	protein histidine kinase activity
BsBEST3145_42140	COG0745	RESPONSE REGULATOR receiver
BsBEST3145_42160	COG0346	lactoylglutathione lyase activity
BsBEST3145_42170	COG0305	Participates in initiation and elongation during chromosome replication
BsBEST3145_42200	COG3093	addiction module antidote protein HigA
BsBEST3145_42210	COG2807	transmembrane transport
BsBEST3145_42220	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BsBEST3145_42230	COG0359	binds to the 23S rRNA
BsBEST3145_42240	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BsBEST3145_42250	COG4241	membrane
BsBEST3145_42270	COG5577	PFAM Coat F domain
BsBEST3145_42280	COG5577	PFAM Coat F domain
BsBEST3145_42290	COG1733	regulation of RNA biosynthetic process
BsBEST3145_42300	COG1227	inorganic diphosphatase activity
BsBEST3145_42330	COG2271	Major facilitator Superfamily
BsBEST3145_42340	COG0789	Transcriptional regulator
BsBEST3145_42340	COG4978	Transcriptional regulator
BsBEST3145_42360	COG4319	ketosteroid isomerase
BsBEST3145_42370	COG1357	PFAM Pentapeptide repeats (8 copies)
BsBEST3145_42380	COG2814	Major facilitator Superfamily
BsBEST3145_42390	COG0583	DNA-binding transcription factor activity
BsBEST3145_42400	COG2153	protein acetylation
BsBEST3145_42420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BsBEST3145_42430	COG1846	Transcriptional regulator
BsBEST3145_42440	COG2153	protein acetylation
BsBEST3145_42450	COG2364	Membrane
BsBEST3145_42460	COG0456	acetyltransferase
BsBEST3145_42470	COG2315	Protein conserved in bacteria
BsBEST3145_42480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BsBEST3145_42490	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3145_42500	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BsBEST3145_42510	COG1331	Highly conserved protein containing a thioredoxin domain
BsBEST3145_42520	COG1266	CAAX protease self-immunity
BsBEST3145_42530	COG2814	Major facilitator Superfamily
BsBEST3145_42530	COG0477	Major facilitator Superfamily
BsBEST3145_42540	COG0346	lactoylglutathione lyase activity
BsBEST3145_42550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BsBEST3145_42560	COG0542	response to heat
BsBEST3145_42580	COG1609	Transcriptional regulator
BsBEST3145_42590	COG0708	Exodeoxyribonuclease III
BsBEST3145_42600	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BsBEST3145_42610	COG0629	single-stranded DNA binding
BsBEST3145_42620	COG0360	Binds together with S18 to 16S ribosomal RNA
BsBEST3145_42630	COG0012	GTP binding
BsBEST3145_42640	COG0243	molybdopterin cofactor binding
BsBEST3145_42650	COG4481	Protein conserved in bacteria
BsBEST3145_42660	COG3949	Membrane
BsBEST3145_42680	COG1475	DNA binding
BsBEST3145_42690	COG1192	Involved in chromosome partitioning
BsBEST3145_42710	COG1475	DNA binding
BsBEST3145_42720	COG0357	Ribosomal RNA small subunit methyltransferase G
BsBEST3145_42730	COG0445	tRNA wobble uridine modification
BsBEST3145_42740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BsBEST3145_42750	COG1847	R3H domain protein
BsBEST3145_42760	COG0706	membrane insertase activity
BsBEST3145_42770	COG0594	ribonuclease P activity