locus_tag old_locus_tag gene Name start end strand product note type ID NCBI BSBS38_00001 BSBS38_00001 BSBS38_00001 70 1329 + Chromosomal replication initiator protein DnaA Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replicatio%3B it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids%3B Belongs to the DnaA family gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00001 BSBS38_00002 BSBS38_00002 dnaN dnaN 1518 2654 + DNA-directed DNA polymerase KEGG: bsu:BSU00020 DNA polymerase III subunit beta gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00002 BSBS38_00003 BSBS38_00003 BSBS38_00003 2785 3000 + uncharacterized protein Contains 1 S4 RNA-binding domain gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00003 BSBS38_00004 BSBS38_00004 BSBS38_00004 3016 4128 + DNA replication and repair protein RecF The RecF protein is involved in DNA metabolis%3B it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded%2C linear DNA. It also seems to bind ATP%3B Belongs to the RecF family gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00004 BSBS38_00005 BSBS38_00005 BSBS38_00005 4146 4391 + uncharacterized protein gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00005 BSBS38_00006 BSBS38_00006 gyrB gyrB 4440 6362 + DNA topoisomerase (ATP-hydrolyzing) DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the type II topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bsl:A7A1_1295 DNA gyrase subunit B gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00006 BSBS38_00007 BSBS38_00007 gyrA gyrA 6573 9038 + DNA topoisomerase (ATP-hydrolyzing) DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the topoisomerase GyrA/ParC subunit family%3B KEGG: bsu:BSU00070 DNA gyrase subunit A gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00007 BSBS38_00008 BSBS38_00008 BSBS38_00008 9327 10876 + 16S ribosomal RNA rRNA gene7 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00008 BSBS38_00009 BSBS38_00009 BSBS38_00009 10979 11055 + tRNA-Ile tRNA gene8 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00009 BSBS38_00010 BSBS38_00010 BSBS38_00010 11067 11142 + tRNA-Ala tRNA gene9 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00010 BSBS38_00011 BSBS38_00011 BSBS38_00011 11224 14151 + 23S ribosomal RNA rRNA gene10 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00011 BSBS38_00012 BSBS38_00012 BSBS38_00012 14206 14321 + 5S ribosomal RNA rRNA gene11 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00012 BSBS38_00013 BSBS38_00013 BSBS38_00013 14361 15308 - uncharacterized protein gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00013 BSBS38_00014 BSBS38_00014 guaB guaB 15429 16895 + IMP dehydrogenase Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP)%2C the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides%2C and therefore plays an important role in the regulation of cell growth%3B Belongs to the IMPDH/GMPR family%3B Contains 2 CBS domains%3B KEGG: bsu:BSU00090 IMP dehydrogenase gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00014 BSBS38_00015 BSBS38_00015 dacC dacC 17048 18379 + Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bsu:BSU00100 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00015 BSBS38_00016 BSBS38_00016 pdxS pdxS 18576 19460 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP)%2C glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates%2C resulting from enzyme-catalyzed isomerization of RBP and G3P%2C respectively%3B Belongs to the PdxS/SNZ family%3B KEGG: bsu:BSU00110 pyridoxal 5'-phosphate synthase pdxS subunit gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00016 BSBS38_00017 BSBS38_00017 pdxT pdxT 19482 20072 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS%3B Belongs to the glutaminase PdxT/SNO family%3B KEGG: bsu:BSU00120 5'-phosphate synthase pdxT subunit gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00017 BSBS38_00018 BSBS38_00018 sarS sarS 20394 21671 + Serine--tRNA ligase Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine%2C to form the misacylated tRNA L-seryl-tRNA(Sec)%2C which will be further converted into selenocysteinyl-tRNA(Sec)%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily%3B KEGG: dol:Dole_2745 seryl-tRNA synthetase gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00018 BSBS38_00019 BSBS38_00019 BSBS38_00019 21806 21898 + tRNA-Ser tRNA gene18 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00019 BSBS38_00020 BSBS38_00020 BSBS38_00020 22010 22663 - Deoxyadenosine kinase Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the nucleoside is less strict. Both 2-deoxyribose%2C ribose%2C and arabinose nucleosides are phosphorylated%2C although the 2-deoxyribonucleosides are preferred. The phosphate donor specificity is dependent on the deoxyribonucleoside substrate%2C but GTP is efficient with both deoxycytidine and deoxyadenosine. Only nucleoside triphosphates can act as phosphate donors%3B Belongs to the DCK/DGK family%3B KEGG: bso:BSNT_00031 deoxyadenosine/deoxycytidine kinase gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00020 BSBS38_00021 BSBS38_00021 BSBS38_00021 22660 23283 - Deoxyguanosine kinase Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as phosphate donor than CTP%2C ATP and GTP%3B Belongs to the DCK/DGK family%3B KEGG: bsu:BSU00150 deoxyguanosine kinase gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00021 BSBS38_00022 BSBS38_00022 BSBS38_00022 23382 24665 - Spore germination protein YaaH May be required for the L-alanine-stimulated germination pathway%3B Contains 2 LysM repeats gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00022 BSBS38_00023 BSBS38_00023 entB entB 24735 25280 - Isochorismatase Belongs to the isochorismatase family%3B KEGG: tfu:Tfu_1870 bifunctional isochorismate lyase / aryl carrier protein gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00023 BSBS38_00024 BSBS38_00024 tadA tadA 25366 25851 + tRNA(adenine(34)) deaminase Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: eca:ECA3260 tRNA(adenine34) deaminase gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00024 BSBS38_00025 BSBS38_00025 dnaX dnaX 26328 28019 + DNA-directed DNA polymerase DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. Belongs to the DnaX/STICHEL family%3B KEGG: bsu:BSU00190 DNA polymerase III subunit gamma/tau gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00025 BSBS38_00026 BSBS38_00026 BSBS38_00026 28043 28366 + Nucleoid-associated protein Binds to DNA and alters its conformation. May be involved in regulation of gene expression%2C nucleoid organization and DNA protection%3B Belongs to the YbaB/EbfC family gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00026 BSBS38_00027 BSBS38_00027 BSBS38_00027 28381 28977 + Recombination protein RecR May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO%3B Belongs to the RecR family%3B Contains 1 Toprim domain gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00027 BSBS38_00028 BSBS38_00028 BSBS38_00028 28995 29219 + uncharacterized protein gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00028 BSBS38_00029 BSBS38_00029 BSBS38_00029 29286 29549 + Sigma-K factor-processing regulatory protein BofA Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB-processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site%2C preventing access of a water molecule and the sequence of pro- sigma K%2C which are necessary for peptide bond hydrolysis to produce sigma-K gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00029 BSBS38_00030 BSBS38_00030 BSBS38_00030 29796 31345 + 16S ribosomal RNA rRNA gene29 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00030 BSBS38_00031 BSBS38_00031 BSBS38_00031 31448 31524 + tRNA-Ile tRNA gene30 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00031 BSBS38_00032 BSBS38_00032 BSBS38_00032 31536 31611 + tRNA-Ala tRNA gene31 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00032 BSBS38_00033 BSBS38_00033 BSBS38_00033 31693 34619 + 23S ribosomal RNA rRNA gene32 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00033 BSBS38_00034 BSBS38_00034 BSBS38_00034 34753 34868 + 5S ribosomal RNA rRNA gene33 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00034 BSBS38_00035 BSBS38_00035 BSBS38_00035 35047 35241 + Protein CsfB gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00035 BSBS38_00036 BSBS38_00036 BSBS38_00036 35361 35975 + Protein XpaC gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00036 BSBS38_00037 BSBS38_00037 BSBS38_00037 35994 37154 + uncharacterized protein Belongs to the TelA family gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00037 BSBS38_00038 BSBS38_00038 ldcC ldcC 37236 38678 + Lysine decarboxylase Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: cpe:CPE0549 lysine decarboxylase gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00038 BSBS38_00039 BSBS38_00039 BSBS38_00039 38675 39313 + dTMP kinase Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis%3B Belongs to the thymidylate kinase family%3B KEGG: pol:Bpro_2519 dTMP kinase gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00039 BSBS38_00040 BSBS38_00040 BSBS38_00040 39387 39716 + uncharacterized protein gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00040 BSBS38_00041 BSBS38_00041 BSBS38_00041 39729 40169 + uncharacterized protein gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00041 BSBS38_00042 BSBS38_00042 holB holB 40181 41170 + DNA-directed DNA polymerase KEGG: bsu:BSU00310 DNA polymerase III subunit delta' gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00042 BSBS38_00043 BSBS38_00043 BSBS38_00043 41173 42000 + Stage 0 sporulation protein YaaT Essential for the phosphorelay during initiation of sporulation. May control the level of phosphorylated spo0A through spo0E activity during sporulation%3B Contains 1 PSP1 C-terminal domain gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00043 BSBS38_00044 BSBS38_00044 BSBS38_00044 42015 42374 + Initiation-control protein YabA Involved in initiation control of chromosome replication%3B Belongs to the YabA family gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00044 BSBS38_00045 BSBS38_00045 BSBS38_00045 42433 43176 + uncharacterized protein gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00045 BSBS38_00046 BSBS38_00046 BSBS38_00046 43163 43462 + UPF0213 protein YazA Belongs to the UPF0213 family%3B Contains 1 GIY-YIG domain gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00046 BSBS38_00047 BSBS38_00047 rsmI rsmI 43437 44315 + 16S rRNA (cytidine(1402)-2'-O)-methyltransferase Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmI family%3B KEGG: bsu:BSU00360 16S rRNA (cytidine1402-2'-O)-methyltransferase gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00047 BSBS38_00048 BSBS38_00048 BSBS38_00048 44364 44648 - Transition state regulatory protein AbrB Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites%2C it may be the sole repressor of tycA transcription%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis Abh and SpoVT gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00048 BSBS38_00049 BSBS38_00049 marS marS 45149 47143 + Methionine--tRNA ligase Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation%3B Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily%3B Contains 1 tRNA-binding domain%3B KEGG: bsu:BSU00380 methionyl-tRNA synthetase gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00049 BSBS38_00050 BSBS38_00050 tatD tatD 47223 47990 + putative metal-dependent hydrolase YabD Belongs to the TatD-type hydrolase family%3B KEGG: bsu:BSU00390 TatD DNase family protein%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00050 BSBS38_00051 BSBS38_00051 amiA amiA 48146 49459 + N-acetylmuramoyl-L-alanine amidase Contains 1 G5 domain%3B KEGG: aur:HMPREF9243_1865 N-acetylmuramoyl-L-alanine amidase gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00051 BSBS38_00052 BSBS38_00052 rnmV rnmV 49604 50164 + Ribonuclease M5 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step%3B Belongs to the ribonuclease M5 family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU00410 ribonuclease M5 gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00052 BSBS38_00053 BSBS38_00053 ksgA ksgA 50157 51029 + 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily%3B KEGG: bsu:BSU00420 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00053 BSBS38_00054 BSBS38_00054 BSBS38_00054 51173 52063 + Sporulation-specific protease YabG Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross- linking of coat proteins like GerQ%3B Belongs to the peptidase U57 family gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00054 BSBS38_00055 BSBS38_00055 BSBS38_00055 52274 52534 + Protein Veg Stimulates biofilm formation via transcriptional activation of extracellular matrix genes. Acts by repressing SinR activity%2C independently of the SinI%2C SlrA and SlrR pathways. Could also be involved in the regulation of other genes during biofilm and spore formation gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00055 BSBS38_00056 BSBS38_00056 BSBS38_00056 52692 52877 + Protein SspF May play some important role in either sporulation or the dormant spore. Belongs to the alpha/beta-type SASP family gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00056 BSBS38_00057 BSBS38_00057 ispE ispE 53025 53894 + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol%3B Belongs to the GHMP kinase family. IspE subfamily%3B KEGG: rhl:LPU83_0984 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00057 BSBS38_00058 BSBS38_00058 BSBS38_00058 53950 54807 + Pur operon repressor Controls the transcription of the pur operon for purine biosynthetic genes%2C binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate. Belongs to the purine/pyrimidine phosphoribosyltransferase family gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00058 BSBS38_00059 BSBS38_00059 ridA ridA 54804 55181 + 2-iminobutanoate/2-iminopropanoate deaminase Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities. Involved in the isoleucine biosynthesis. May have a role in the purine metabolism%3B Belongs to the RutC family%3B KEGG: ype:YPO3590 2-iminobutanoate/2-iminopropanoate deaminase gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00059 BSBS38_00060 BSBS38_00060 BSBS38_00060 55376 55669 + Putative septation protein SpoVG Could be involved in septation%3B Belongs to the SpoVG family gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00060 BSBS38_00061 BSBS38_00061 glmU glmU 55862 57232 + UDP-N-acetylglucosamine diphosphorylase Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: bsu:BSU00500 bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00061 BSBS38_00062 BSBS38_00062 prpS prpS 57255 58208 + Ribose-phosphate diphosphokinase Involved in the biosynthesis of ribose 1%2C5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP%3B Belongs to the ribose-phosphate pyrophosphokinase family%3B KEGG: bsu:BSU00510 ribose-phosphate pyrophosphokinase gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00062 BSBS38_00063 BSBS38_00063 BSBS38_00063 58293 58907 + General stress protein CTC Not required for exponential growt%3B probably functions in vegetatively growing cells%2C maybe required for accurate translation under stress conditions. Belongs to the ribosomal protein L25P family. CTC subfamily gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00063 BSBS38_00064 BSBS38_00064 pth1 pth1 59014 59580 + Aminoacyl-tRNA hydrolase The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis%3B Belongs to the PTH family%3B KEGG: cff:CFF8240_0337 peptidyl-tRNA hydrolase%2C PTH1 family gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00064 BSBS38_00065 BSBS38_00065 BSBS38_00065 59640 59870 + uncharacterized protein gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00065 BSBS38_00066 BSBS38_00066 BSBS38_00066 59940 63473 + Transcription-repair-coupling factor Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA%2C and recruitment of nucleotide excision repair machinery to the damaged site%3B In the N-terminal sectio%3B belongs to the UvrB family%3B In the C-terminal sectio%3B belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU00550 transcription-repair coupling factor (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00066 BSBS38_00067 BSBS38_00067 BSBS38_00067 63609 64145 + Stage V sporulation protein Positive and negative transcriptional regulator of sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and Abh gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00067 BSBS38_00068 BSBS38_00068 BSBS38_00068 64327 65925 + putative membrane protein YabM Belongs to the polysaccharide synthase family gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00068 BSBS38_00069 BSBS38_00069 BSBS38_00069 65915 67384 + uncharacterized protein gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00069 BSBS38_00070 BSBS38_00070 BSBS38_00070 67387 67647 + uncharacterized protein Contains 1 S4 RNA-binding domain gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00070 BSBS38_00071 BSBS38_00071 BSBS38_00071 67726 68028 + Spore protein YabP Required for sporulation gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00071 BSBS38_00072 BSBS38_00072 BSBS38_00072 68025 68660 + Spore protein YabQ Required for sporulation. Plays an important role in cortex and coat formation gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00072 BSBS38_00073 BSBS38_00073 BSBS38_00073 68678 69055 + Cell division protein DivIC gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00073 BSBS38_00074 BSBS38_00074 BSBS38_00074 69136 69522 + uncharacterized protein Belongs to the peptidase U57 family%3B Contains 1 S1 motif domain gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00074 BSBS38_00075 BSBS38_00075 BSBS38_00075 69690 69766 + tRNA-Met tRNA gene74 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00075 BSBS38_00076 BSBS38_00076 BSBS38_00076 69776 69847 + tRNA-Glu tRNA gene75 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00076 BSBS38_00077 BSBS38_00077 BSBS38_00077 70047 72530 + Protein-serine/threonine phosphatase Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation. Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU00640 stage II sporulation protein E gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00077 BSBS38_00078 BSBS38_00078 BSBS38_00078 72615 73352 + uncharacterized protein gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00078 BSBS38_00079 BSBS38_00079 BSBS38_00079 73318 74277 + Non-specific serine/threonine protein kinase Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bsu:BSU00660 serine/threonine protein kinase%2C bacterial gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00079 BSBS38_00080 BSBS38_00080 tilS tilS 74436 75854 + tRNA(Ile)-lysidine synthetase Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%2C in an ATP-dependent manner. Cytidine is converted to lysidine%2C thus changing the amino acid specificity of the tRNA from methionine to isoleucine%3B Belongs to the tRNA(Ile)-lysidine synthase family%3B KEGG: bsu:BSU00670 tRNA(Ile)-lysidine synthase gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00080 BSBS38_00081 BSBS38_00081 hprT hprT 75851 76393 + Hypoxanthine phosphoribosyltransferase Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bsu:BSU00680 hypoxanthine phosphoribosyltransferase gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00081 BSBS38_00082 BSBS38_00082 ftsH ftsH 76491 78404 + ATP-dependent zinc metalloprotease FtsH Acts as a processive%2C ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins%3B In the central sectio%3B belongs to the AAA ATPase family%3B In the C-terminal sectio%3B belongs to the peptidase M41 family%3B KEGG: bsu:BSU00690 cell division protease FtsH%3B Metalloendopeptidases gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00082 BSBS38_00083 BSBS38_00083 coaX coaX 78599 79375 + Pantothenate kinase Catalyzes the phosphorylation of pantothenate (Pan)%2C the first step in CoA biosynthesis%3B Belongs to the type III pantothenate kinase family%3B KEGG: gsu:GSU1934 type III pantothenate kinase gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00083 BSBS38_00084 BSBS38_00084 BSBS38_00084 79387 80262 + 33 kDa chaperonin Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress%3B Belongs to the HSP33 family gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00084 BSBS38_00085 BSBS38_00085 prsA prsA 80309 81202 + Peptidylprolyl isomerase Contains 1 PpiC domain%3B KEGG: bmet:BMMGA3_00405 foldase protein PrsA gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00085 BSBS38_00086 BSBS38_00086 cysK cysK 81278 82204 + Cysteine synthase Catalyzes the conversion of O-acetylserine to cysteine. Also acts as a sensor of cysteine availability in the signal transduction pathway modulating CymR activity. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bsu:BSU00730 cysteine synthase A gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00086 BSBS38_00087 BSBS38_00087 pabB pabB 82371 83783 + Aminodeoxychorismate synthase Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC%3B Belongs to the anthranilate synthase component I family%3B KEGG: bsu:BSU00740 para-aminobenzoate synthetase component I gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00087 BSBS38_00088 BSBS38_00088 pabA pabA 83806 84381 + Aminodeoxychorismate synthase Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate%2C an intermediate in the biosynthesis of L-tryptophan. In the first step%2C the glutamine- binding beta subunit of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by the large alpha subunit of AS to produce anthranilate. Plays an important regulatory role in auxin production via the tryptophan-dependent biosynthetic pathway%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: eco:b3360 para-aminobenzoate synthetase component II gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00088 BSBS38_00089 BSBS38_00089 BSBS38_00089 84381 85262 + D-amino-acid transaminase Involved in the biosynthesis of p-aminobenzoate (PABA)%2C a precursor of tetrahydrofolate. Converts 4-amino-4- deoxychorismate into 4-aminobenzoate (PABA) and pyruvate (By similarity)%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: serr:Ser39006_3473 D-alanine transaminase gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00089 BSBS38_00090 BSBS38_00090 folP folP 85244 86101 + Dihydropteroate synthase Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7%2C8-dihydropterin diphosphate (DHPt-PP) to form 7%2C8-dihydropteroate (H2Pte)%2C the immediate precursor of folate derivatives%3B Belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bsu:BSU00770 dihydropteroate synthase gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00090 BSBS38_00091 BSBS38_00091 folB folB 86094 86456 + Dihydroneopterin aldolase Catalyzes the conversion of 7%2C8-dihydroneopterin to 6- hydroxymethyl-7%2C8-dihydropterin%3B Belongs to the DHNA family%3B KEGG: xft:PD1642 dihydroneopterin aldolase gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00091 BSBS38_00092 BSBS38_00092 folK folK 86453 86956 + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase Belongs to the HPPK family%3B KEGG: bsu:BSU00790 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00092 BSBS38_00093 BSBS38_00093 BSBS38_00093 86908 87117 + putative HTH-type transcriptional regulator YazB Contains 1 HTH cro/C1-type DNA-binding domain gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00093 BSBS38_00094 BSBS38_00094 dusB dusB 87141 88142 + putative tRNA-dihydrouridine synthase Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: rpo:MA1_00045 tRNA-dihydrouridine synthase B%3B Oxidoreductases gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00094 BSBS38_00095 BSBS38_00095 karS karS 88234 89733 + Lysine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU00820 lysyl-tRNA synthetase%2C class II gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00095 BSBS38_00096 BSBS38_00096 BSBS38_00096 90044 91593 + 16S ribosomal RNA rRNA gene95 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00096 BSBS38_00097 BSBS38_00097 BSBS38_00097 91764 94691 + 23S ribosomal RNA rRNA gene96 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00097 BSBS38_00098 BSBS38_00098 BSBS38_00098 94746 94861 + 5S ribosomal RNA rRNA gene97 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00098 BSBS38_00099 BSBS38_00099 BSBS38_00099 94884 94959 + tRNA-Val tRNA gene98 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00099 BSBS38_00100 BSBS38_00100 BSBS38_00100 94964 95039 + tRNA-Thr tRNA gene99 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00100 BSBS38_00101 BSBS38_00101 BSBS38_00101 95076 95151 + tRNA-Lys tRNA gene100 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00101 BSBS38_00102 BSBS38_00102 BSBS38_00102 95158 95240 + tRNA-Leu tRNA gene101 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00102 BSBS38_00103 BSBS38_00103 BSBS38_00103 95281 95355 + tRNA-Gly tRNA gene102 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00103 BSBS38_00104 BSBS38_00104 BSBS38_00104 95370 95455 + tRNA-Leu tRNA gene103 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00104 BSBS38_00105 BSBS38_00105 BSBS38_00105 95465 95541 + tRNA-Arg tRNA gene104 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00105 BSBS38_00106 BSBS38_00106 BSBS38_00106 95569 95645 + tRNA-Pro tRNA gene105 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00106 BSBS38_00107 BSBS38_00107 BSBS38_00107 95654 95729 + tRNA-Ala tRNA gene106 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00107 BSBS38_00108 BSBS38_00108 BSBS38_00108 95903 97452 + 16S ribosomal RNA rRNA gene107 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00108 BSBS38_00109 BSBS38_00109 BSBS38_00109 97623 100550 + 23S ribosomal RNA rRNA gene108 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00109 BSBS38_00110 BSBS38_00110 BSBS38_00110 100684 100799 + 5S ribosomal RNA rRNA gene109 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00110 BSBS38_00111 BSBS38_00111 BSBS38_00111 101040 101504 + Transcriptional regulator CtsR Controls the expression of the cellular protein quality control genes clpC%2C clpE and clpP%2C as well as mcsA and mcsB. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock%2C CtsR is degraded by the ClpCP and ClpEP proteolytic systems%2C ensuring the derepression of clpE%2C clpP and the clpC operon. CtsR negatively autoregulates its own synthesis%3B Belongs to the CtsR family gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00111 BSBS38_00112 BSBS38_00112 BSBS38_00112 101728 102075 + Protein-arginine kinase activator protein Activates the phosphorylation activity of the protein- arginine kinase McsB. Is required for the delocalization of competence proteins from the cell poles%3B Contains 1 UVR domain gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00112 BSBS38_00113 BSBS38_00113 mcsB mcsB 102075 103166 + Protein arginine kinase Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the ATP:guanido phosphotransferase family%3B Contains 1 phosphagen kinase C-terminal domain%3B KEGG: bsu:BSU00850 protein arginine kinase gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00113 BSBS38_00114 BSBS38_00114 BSBS38_00114 103163 105595 + Chaperone protein ClpB Part of a stress-induced multi-chaperone system%2C it is involved in the recovery of the cell from heat-induced damage%2C in cooperation with DnaK%2C DnaJ and GrpE. Acts before DnaK%2C in the processing of protein aggregates. Protein binding stimulates the ATPase activit%3B ATP hydrolysis unfolds the denatured protein aggregates%2C which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates%2C contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)%3B Belongs to the ClpA/ClpB family%3B Contains 1 UVR domain gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00114 BSBS38_00115 BSBS38_00115 BSBS38_00115 105630 107057 + DNA repair protein RadA like protein May play a role in the repair of endogenous alkylation damage%3B Belongs to the RecA family. RadA subfamily gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00115 BSBS38_00116 BSBS38_00116 disA disA 107061 108143 + Diadenylate cyclase Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. Forms globular foci that rapidly scan along the chromosomes during sporulation%2C searching for lesions. Its ability to scan through the chromosome rapidly is due to its nonspecific DNA-binding. When a lesion is present%2C DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. It is required%2C at least partially%2C to inhibit the activity of the transcription factor spo0A%2C which controls%2C among others%2C early sporulation genes. Has also diadenylate cyclase activity%2C catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome%2C operates as a positive signal that advances sporulatio%3B upon encountering a lesion%2C the DisA focus arrests at the damaged site and halts c-di- AMP synthesis. Does not convert GTP to c-di-GMP. Belongs to the DisA family%3B KEGG: bsu:BSU00880 diadenylate cyclase gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00116 BSBS38_00117 BSBS38_00117 BSBS38_00117 108259 109359 + putative PIN and TRAM-domain containing protein YacL An RNase%3B Belongs to the ycf81 family%3B In the central sectio%3B belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B Contains 1 TRAM domain gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00117 BSBS38_00118 BSBS38_00118 ispD ispD 109374 110072 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)%3B Belongs to the IspD family%3B KEGG: bsu:BSU00900 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00118 BSBS38_00119 BSBS38_00119 ispF ispF 110065 110541 + 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD)%2C and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2%2C4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)%3B In the N-terminal sectio%3B belongs to the IspD family%3B In the C-terminal sectio%3B belongs to the IspF family%3B KEGG: ctu:CTU_33200 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00119 BSBS38_00120 BSBS38_00120 gltX gltX 110632 112083 + Glutamate--tRNA(Gln) ligase Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU00920 nondiscriminating glutamyl-tRNA synthetase gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00120 BSBS38_00121 BSBS38_00121 cysE cysE 112384 113037 + Serine O-acetyltransferase Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS)%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: cha:CHAB381_0927 serine O-acetyltransferase gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00121 BSBS38_00122 BSBS38_00122 carS carS 113034 114434 + Cysteine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: fau:Fraau_2118 cysteinyl-tRNA synthetase gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00122 BSBS38_00123 BSBS38_00123 BSBS38_00123 114438 114869 + Mini-ribonuclease Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc%3B Rnc processes 30S rRNA into smaller rRNA precursors. Cleaves more efficiently on assembled 50S ribosomal subunits. Cleavage is strongly stimulated by ribosomal protein L3 (RplC%3B 20-30%25 DMSO can replace RplC%2C suggesting RplC may alter rRNA conformation%3B Belongs to the MrnC RNase family%3B KEGG: bsu:BSU00950 ribonuclease III family protein%3B Endoribonucleases producing 5'-phosphomonoesters gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00123 BSBS38_00124 BSBS38_00124 rlmB rlmB 114853 115602 + 23S rRNA (guanosine(2251)-2'-O)-methyltransferase Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family%3B KEGG: bsu:BSU00960 23S rRNA (guanosine2251-2'-O)-methyltransferase gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00124 BSBS38_00125 BSBS38_00125 BSBS38_00125 115609 116121 + uncharacterized protein gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00125 BSBS38_00126 BSBS38_00126 BSBS38_00126 116123 116839 + RNA polymerase sigma-H factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation. It is also required for transcription of several stationary phase genes. Belongs to the sigma-70 factor family gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00126 BSBS38_00127 BSBS38_00127 BSBS38_00127 117115 117294 + Protein translocase subunit SecE Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation%3B Belongs to the SecE/SEC61-gamma family gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00127 BSBS38_00128 BSBS38_00128 BSBS38_00128 117437 118006 + Transcription termination/antitermination protein NusG Participates in transcription elongation%2C termination and antitermination%3B Belongs to the NusG family%3B Contains 1 KOW domain gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00128 BSBS38_00129 BSBS38_00129 BSBS38_00129 118174 118599 + 50S ribosomal protein L11-1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors%3B Belongs to the ribosomal protein L11P family gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00129 BSBS38_00130 BSBS38_00130 BSBS38_00130 118694 119392 + 50S ribosomal protein L1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome%2C and is involved in E site tRNA release%3B Protein L1 is also a translational repressor protein%2C it controls the translation of the L11 operon by binding to its mRNA%3B Belongs to the ribosomal protein L1P family gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00130 BSBS38_00131 BSBS38_00131 BSBS38_00131 119644 120144 + 50S ribosomal protein L10 Forms part of the ribosomal stalk%2C playing a central role in the interaction of the ribosome with GTP-bound translation factors%3B Belongs to the ribosomal protein L10P family gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00131 BSBS38_00132 BSBS38_00132 BSBS38_00132 120190 120561 + 50S ribosomal protein L7/L12 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation%3B Belongs to the ribosomal protein L7/L12P family gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00132 BSBS38_00133 BSBS38_00133 rsmC rsmC 120651 121256 + 16S rRNA (guanine(1207)-N(2))-methyltransferase Belongs to the methyltransferase superfamily%3B KEGG: bsu:BSU01060 16S rRNA (guanine1207-N2)-methyltransferase gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00133 BSBS38_00134 BSBS38_00134 rpoB rpoB 121502 125083 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta chain family%3B KEGG: bsu:BSU01070 DNA-directed RNA polymerase subunit beta gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00134 BSBS38_00135 BSBS38_00135 rpoC rpoC 125145 128744 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta' chain family%3B KEGG: ssdc:SSDC_00130 DNA-directed RNA polymerase subunit beta' gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00135 BSBS38_00136 BSBS38_00136 BSBS38_00136 128923 129171 + Putative ribosomal protein L7Ae-like protein Belongs to the ribosomal protein L7Ae family gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00136 BSBS38_00137 BSBS38_00137 BSBS38_00137 129285 129701 + 30S ribosomal protein S12 With S4 and S5 plays an important role in translational accuracy%3B Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits%2C it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8%2C S12 and S17 appears to hold together the shoulder and platform of the 30S subunit%3B Belongs to the ribosomal protein S12P family gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00137 BSBS38_00138 BSBS38_00138 BSBS38_00138 129743 130213 + 30S ribosomal protein S7 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center%2C probably blocks exit of the E-site tRNA%3B Belongs to the ribosomal protein S7P family gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00138 BSBS38_00139 BSBS38_00139 BSBS38_00139 130267 132345 + Elongation factor G Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step%2C the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites%2C respectively. Catalyzes the coordinated movement of the two tRNA molecules%2C the mRNA and conformational changes in the ribosome%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00139 BSBS38_00140 BSBS38_00140 BSBS38_00140 132465 133655 + Elongation factor Tu-A This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00140 BSBS38_00141 BSBS38_00141 BSBS38_00141 133754 134335 + Prolyl aminopeptidase Probable aminopeptidase%3B Belongs to the peptidase S33 family%3B KEGG: bcz:BCZK3858 proline iminopeptidase gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00141 BSBS38_00142 BSBS38_00142 BSBS38_00142 134422 134709 + Prolyl aminopeptidase Probable aminopeptidase%3B Belongs to the peptidase S33 family%3B KEGG: bcz:BCZK3858 proline iminopeptidase gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00142 BSBS38_00143 BSBS38_00143 BSBS38_00143 134946 135254 + 30S ribosomal protein S10%2C chloroplastic Involved in the binding of tRNA to the ribosomes%3B Belongs to the ribosomal protein S10P family gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00143 BSBS38_00144 BSBS38_00144 BSBS38_00144 135294 135923 + 50S ribosomal protein L3 One of the primary rRNA binding proteins%2C it binds directly near the 3'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B Belongs to the ribosomal protein L3P family gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00144 BSBS38_00145 BSBS38_00145 BSBS38_00145 135951 136574 + 50S ribosomal protein L4 One of the primary rRNA binding proteins%2C this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome%3B Forms part of the polypeptide exit tunnel%3B Belongs to the ribosomal protein L4P family gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00145 BSBS38_00146 BSBS38_00146 BSBS38_00146 136574 136861 + 50S ribosomal protein L23 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome%3B Belongs to the ribosomal protein L23P family gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00146 BSBS38_00147 BSBS38_00147 BSBS38_00147 136893 137726 + 50S ribosomal protein L2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activit%3B this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome%3B Belongs to the ribosomal protein L2P family gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00147 BSBS38_00148 BSBS38_00148 BSBS38_00148 137784 138062 + 30S ribosomal protein S19%2C chloroplastic Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA%3B Belongs to the ribosomal protein S19P family gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00148 BSBS38_00149 BSBS38_00149 BSBS38_00149 138079 138420 + 50S ribosomal protein L22%2C chloroplastic This protein binds specifically to 23S rRNA%3B The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit%2C while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome%3B Belongs to the ribosomal protein L22P family gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00149 BSBS38_00150 BSBS38_00150 BSBS38_00150 138424 139080 + 30S ribosomal protein S3%2C chloroplastic Belongs to the ribosomal protein S3P family%3B Contains 1 KH type-2 domain gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00150 BSBS38_00151 BSBS38_00151 BSBS38_00151 139082 139516 + 50S ribosomal protein L16%2C plastid Belongs to the ribosomal protein L16P family gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00151 BSBS38_00152 BSBS38_00152 BSBS38_00152 139506 139706 + 50S ribosomal protein L29 Belongs to the ribosomal protein L29P family gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00152 BSBS38_00153 BSBS38_00153 BSBS38_00153 139729 139992 + 30S ribosomal protein S17 One of the primary rRNA binding proteins%2C it binds specifically to the 5'-end of 16S ribosomal RNA%3B Belongs to the ribosomal protein S17P family gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00153 BSBS38_00154 BSBS38_00154 BSBS38_00154 140033 140401 + 50S ribosomal protein L14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome%3B Belongs to the ribosomal protein L14P family gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00154 BSBS38_00155 BSBS38_00155 BSBS38_00155 140464 140748 + 50S ribosomal protein L24 One of two assembly initiator proteins%2C it binds directly to the 5'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit%3B Belongs to the ribosomal protein L24P family gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00155 BSBS38_00156 BSBS38_00156 BSBS38_00156 140775 141314 + 50S ribosomal protein L5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b)%2C connecting the 2 subunit%3B this bridge is implicated in subunit movement. Contacts the P site tRN%3B the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs%3B Belongs to the ribosomal protein L5P family gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00156 BSBS38_00157 BSBS38_00157 BSBS38_00157 141337 141522 + 30S ribosomal protein S14 type Z Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family. Zinc- binding S14P subfamily gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00157 BSBS38_00158 BSBS38_00158 BSBS38_00158 141554 141952 + 30S ribosomal protein S8 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit%3B Belongs to the ribosomal protein S8P family gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00158 BSBS38_00159 BSBS38_00159 BSBS38_00159 141982 142521 + 50S ribosomal protein L6 This protein binds to the 23S rRNA%2C and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk%2C and near the tRNA binding site of the peptidyltransferase center%3B Belongs to the ribosomal protein L6P family gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00159 BSBS38_00160 BSBS38_00160 BSBS38_00160 142554 142916 + 50S ribosomal protein L18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance%3B Belongs to the ribosomal protein L18P family gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00160 BSBS38_00161 BSBS38_00161 BSBS38_00161 142935 143441 + 30S ribosomal protein With S4 and S12 plays an important role in translational accuracy%3B Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body%3B Belongs to the ribosomal protein S5P family%3B Contains 1 S5 DRBM domain gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00161 BSBS38_00162 BSBS38_00162 BSBS38_00162 143455 143634 + 50S ribosomal protein L30 Belongs to the ribosomal protein L30P family gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00162 BSBS38_00163 BSBS38_00163 BSBS38_00163 143665 144105 + 50S ribosomal protein L15 Binds to the 23S rRNA%3B Belongs to the ribosomal protein L15P family gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00163 BSBS38_00164 BSBS38_00164 BSBS38_00164 144107 145402 + Protein translocase subunit SecY The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7%2C and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently%3B Belongs to the SecY/SEC61-alpha family gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00164 BSBS38_00165 BSBS38_00165 BSBS38_00165 145457 146110 + Adenylate kinase Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism%3B Belongs to the adenylate kinase family%3B KEGG: cbu:CBU_0454 adenylate kinase gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00165 BSBS38_00166 BSBS38_00166 BSBS38_00166 146107 146853 + Methionyl aminopeptidase Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: bsu:BSU01380 methionyl aminopeptidase gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00166 BSBS38_00167 BSBS38_00167 BSBS38_00167 147165 147383 + Translation initiation factor IF-1 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection%2C yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1%2C IF-2 and IF-3 are released leaving the mature 70S translation initation complex%3B Belongs to the IF-1 family%3B Contains 1 S1-like domain gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00167 BSBS38_00168 BSBS38_00168 BSBS38_00168 147417 147530 + 50S ribosomal protein L36%2C chloroplastic Belongs to the ribosomal protein L36P family gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00168 BSBS38_00169 BSBS38_00169 BSBS38_00169 147553 147918 + Cyanelle 30S ribosomal protein S13 Located at the top of the head of the 30S subunit%2C it contacts several helices of the 16S rRNA%3B Belongs to the ribosomal protein S13P family gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00169 BSBS38_00170 BSBS38_00170 BSBS38_00170 147939 148334 + 30S ribosomal protein S11 Located on the platform of the 30S subunit%2C it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome%3B Belongs to the ribosomal protein S11P family gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00170 BSBS38_00171 BSBS38_00171 rpoA rpoA 148511 149455 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase alpha chain family%3B KEGG: bsu:BSU01430 DNA-directed RNA polymerase subunit alpha gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00171 BSBS38_00172 BSBS38_00172 BSBS38_00172 149533 149895 + 50S ribosomal protein L17 Belongs to the ribosomal protein L17P family gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00172 BSBS38_00173 BSBS38_00173 BSBS38_00173 150025 150870 + Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU01450 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00173 BSBS38_00174 BSBS38_00174 BSBS38_00174 150846 151715 + Energy-coupling factor transporter ATP-binding protein EcfA2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00174 BSBS38_00175 BSBS38_00175 BSBS38_00175 151712 152509 + Energy-coupling factor transporter transmembrane protein EcfT Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the energy-coupling factor EcfT family gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00175 BSBS38_00176 BSBS38_00176 truA truA 152519 153262 + tRNA pseudouridine(38-40) synthase Formation of pseudouridine at positions 38%2C 39 and 40 in the anticodon stem and loop of transfer RNAs%3B Belongs to the tRNA pseudouridine synthase TruA family%3B KEGG: bsu:BSU01480 tRNA pseudouridine38-40 synthase gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00176 BSBS38_00177 BSBS38_00177 BSBS38_00177 153424 153861 + 50S ribosomal protein L13 This protein is one of the early assembly proteins of the 50S ribosomal subunit%2C although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly%3B Belongs to the ribosomal protein L13P family gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00177 BSBS38_00178 BSBS38_00178 BSBS38_00178 153882 154274 + 30S ribosomal protein S9 Belongs to the ribosomal protein S9P family gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00178 BSBS38_00179 BSBS38_00179 BSBS38_00179 154732 155499 + putative methyltransferase YbaJ Belongs to the methyltransferase superfamily gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00179 BSBS38_00180 BSBS38_00180 BSBS38_00180 155685 156128 + uncharacterized protein gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00180 BSBS38_00181 BSBS38_00181 BSBS38_00181 156188 156901 + N-acetylmuramoyl-L-alanine amidase Cleaves the peptide side chain from the N-acetylmuramic acid residues in peptidoglycan. This is a step in the formation of muramic delta-lactam residues in spore cortex%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bsu:BSU01530 N-acetylmuramoyl-L-alanine amidase gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00181 BSBS38_00182 BSBS38_00182 BSBS38_00182 156997 158055 + Iron-sulfur cluster carrier protein Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP%3B Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect%3B Belongs to the Mrp/NBP35 ATP-binding proteins family gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00182 BSBS38_00183 BSBS38_00183 BSBS38_00183 158091 158648 - Spore germination protein GerD gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00183 BSBS38_00184 BSBS38_00184 BSBS38_00184 158758 159354 + KinB-signaling pathway activation protein Involved in the activation of the KinB signaling pathway of sporulation gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00184 BSBS38_00185 BSBS38_00185 pdaA pdaA 159355 160119 - putative polysaccharide deacetylase PdaB Necessary to maintain spores after the late stage of sporulation. Might be involved in cortex formation%3B Belongs to the polysaccharide deacetylase family%3B KEGG: tjr:TherJR_1209 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00185 BSBS38_00186 BSBS38_00186 BSBS38_00186 160472 162021 + 16S ribosomal RNA rRNA gene185 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00186 BSBS38_00187 BSBS38_00187 BSBS38_00187 162192 165119 + 23S ribosomal RNA rRNA gene186 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00187 BSBS38_00188 BSBS38_00188 BSBS38_00188 165175 165290 + 5S ribosomal RNA rRNA gene187 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00188 BSBS38_00189 BSBS38_00189 BSBS38_00189 165335 165409 + tRNA-Asn tRNA gene188 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00189 BSBS38_00190 BSBS38_00190 BSBS38_00190 165412 165484 + tRNA-Thr tRNA gene189 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00190 BSBS38_00191 BSBS38_00191 BSBS38_00191 165545 165619 + tRNA-Gly tRNA gene190 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00191 BSBS38_00192 BSBS38_00192 BSBS38_00192 165651 165727 + tRNA-Arg tRNA gene191 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00192 BSBS38_00193 BSBS38_00193 BSBS38_00193 165755 165831 + tRNA-Pro tRNA gene192 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00193 BSBS38_00194 BSBS38_00194 BSBS38_00194 165840 165915 + tRNA-Ala tRNA gene193 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00194 BSBS38_00195 BSBS38_00195 BSBS38_00195 166089 167637 + 16S ribosomal RNA rRNA gene194 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00195 BSBS38_00196 BSBS38_00196 BSBS38_00196 167808 170735 + 23S ribosomal RNA rRNA gene195 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00196 BSBS38_00197 BSBS38_00197 BSBS38_00197 170791 170906 + 5S ribosomal RNA rRNA gene196 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00197 BSBS38_00198 BSBS38_00198 BSBS38_00198 171094 172643 + 16S ribosomal RNA rRNA gene197 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00198 BSBS38_00199 BSBS38_00199 BSBS38_00199 172814 175741 + 23S ribosomal RNA rRNA gene198 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00199 BSBS38_00200 BSBS38_00200 BSBS38_00200 175797 175912 + 5S ribosomal RNA rRNA gene199 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00200 BSBS38_00201 BSBS38_00201 BSBS38_00201 176497 177933 + Putative sulfate transporter YbaR Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00201 BSBS38_00202 BSBS38_00202 BSBS38_00202 177949 178101 + hypothetical protein gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00202 BSBS38_00203 BSBS38_00203 uxaB uxaB 178040 178999 + Tagaturonate reductase KEGG: sbu:SpiBuddy_3010 tagaturonate reductase gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00203 BSBS38_00204 BSBS38_00204 BSBS38_00204 179009 179761 - uncharacterized protein gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00204 BSBS38_00205 BSBS38_00205 BSBS38_00205 179758 180768 - Iron-uptake system permease protein FeuC Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00205 BSBS38_00206 BSBS38_00206 BSBS38_00206 180761 181765 - Iron-uptake system permease protein FeuB Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00206 BSBS38_00207 BSBS38_00207 BSBS38_00207 181784 182737 - Iron-uptake system-binding protein Involved in the uptake of iron%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00207 BSBS38_00208 BSBS38_00208 BSBS38_00208 182828 184417 - HTH-type transcriptional activator Btr In iron-limited conditions%2C activates expression of the feuABCybbA operon%2C which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin%3B Contains 1 Fe/B12 periplasmic-binding domain%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00208 BSBS38_00209 BSBS38_00209 nagZ nagZ 184608 185852 - Beta-N-acetylhexosaminidase KEGG: hhd:HBHAL_2473 beta-N-acetylhexosaminidase gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00209 BSBS38_00210 BSBS38_00210 BSBS38_00210 185866 187794 - Beta-N-acetylhexosaminidase Cleaves muropeptides%2C but not peptidoglycan%3B Belongs to the glycosyl hydrolase 3 family%3B KEGG: bsu:BSU01660 beta-N-acetylhexosaminidase gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00210 BSBS38_00211 BSBS38_00211 cwlA cwlA 187822 189147 - N-acetylmuramoyl-L-alanine amidase Belongs to the UPF0214 family%3B KEGG: pat:Patl_4160 N-acetylmuramoyl-L-alanine amidase gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00211 BSBS38_00212 BSBS38_00212 scrA scrA 189204 190571 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU01680 PTS system%2C sucrose-specific IIB component gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00212 BSBS38_00213 BSBS38_00213 BSBS38_00213 190597 191448 - putative HTH-type transcriptional regulator YbbH Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00213 BSBS38_00214 BSBS38_00214 murQ murQ 191465 192379 - N-acetylmuramic acid 6-phosphate etherase Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: bsu:BSU01700 N-acetylmuramic acid 6-phosphate etherase gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00214 BSBS38_00215 BSBS38_00215 BSBS38_00215 192489 192971 - Cysteine synthase Contains 1 N-acetyltransferase domain%3B KEGG: bph:Bphy_7479 cysteine synthase A gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00215 BSBS38_00216 BSBS38_00216 BSBS38_00216 192984 193439 - D-alanine--D-alanine ligase KEGG: elm:ELI_4118 D-alanine-D-alanine ligase gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00216 BSBS38_00217 BSBS38_00217 BSBS38_00217 193618 193692 + tRNA-Glu tRNA gene216 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00217 BSBS38_00218 BSBS38_00218 BSBS38_00218 193696 193771 + tRNA-Val tRNA gene217 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00218 BSBS38_00219 BSBS38_00219 BSBS38_00219 193776 193848 + tRNA-Thr tRNA gene218 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00219 BSBS38_00220 BSBS38_00220 BSBS38_00220 193871 193955 + tRNA-Tyr tRNA gene219 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00220 BSBS38_00221 BSBS38_00221 BSBS38_00221 193960 194034 + tRNA-Gln tRNA gene220 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00221 BSBS38_00222 BSBS38_00222 BSBS38_00222 194262 194825 + ECF RNA polymerase sigma factor SigW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RsiW for this protein) until released by regulated membrane proteolysis. Sigma-W controls genes involved in transport processes and detoxification%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00222 BSBS38_00223 BSBS38_00223 BSBS38_00223 194839 195465 + Anti-sigma-W factor RsiW Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW%2C and its proteolytic destruction to sigma-W activation (By similarity)%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00223 BSBS38_00224 BSBS38_00224 dacA dacA 195626 196447 + Diadenylate cyclase KEGG: bsu:BSU01750 diadenylate cyclase gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00224 BSBS38_00225 BSBS38_00225 BSBS38_00225 196440 197894 + YbbR-like domain-containing protein YbbR Contains 4 YbbR-like domains gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00225 BSBS38_00226 BSBS38_00226 glmM glmM 197913 199259 + Phosphoglucosamine mutase Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate%3B Belongs to the phosphohexose mutase family%3B KEGG: scu:SCE1572_24625 phosphoglucosamine mutase gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00226 BSBS38_00227 BSBS38_00227 glmS glmS 199693 201495 + Glutamine--fructose-6-phosphate transaminase (isomerizing) Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source%3B Contains 1 glutamine amidotransferase type-2 domain%3B Contains 2 SIS domains%3B KEGG: alv:Alvin_0239 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00227 BSBS38_00228 BSBS38_00228 alkA alkA 201963 202874 - DNA-3-methyladenine glycosylase II Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Catalyzes the hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions%3B Belongs to the alkylbase DNA glycosidase AlkA family%3B KEGG: bsu:BSU01800 DNA-3-methyladenine glycosylase II gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00228 BSBS38_00229 BSBS38_00229 adaA adaA 203147 203785 + Bifunctional transcriptional activator/DNA repair enzyme AdaA Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues. The methylation of AdaA by methylphosphotriesters in DNA leads to its activation as a transcriptional regulator that activates the transcription of the ada operon which consists of adaA and adaB%2C and of the adjacent gene alkA. Contains 1 HTH araC/xylS-type DNA-binding domain%3B KEGG: bsu:BSU01810 AraC family transcriptional regulator%2C regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase%3B Methyltransferases gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00229 BSBS38_00230 BSBS38_00230 adaB adaB 203769 204311 + Methylated-DNA--[protein]-cysteine S-methyltransferase Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs O6- methylguanine residues in alkylated DNA by a direct and irreversible transfer of the methyl group from the base to one of its own cysteine residues%3B Belongs to the MGMT family%3B KEGG: bjs:MY9_0187 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00230 BSBS38_00231 BSBS38_00231 ndhF ndhF 204830 206347 + NADH:ubiquinone reductase (H(+)-translocating) Belongs to the complex I subunit 5 family%3B KEGG: bsu:BSU01830 NAD(P)H-quinone oxidoreductase subunit 5 gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00231 BSBS38_00232 BSBS38_00232 BSBS38_00232 206362 208977 + UPF0753 protein Belongs to the UPF0753 family gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00232 BSBS38_00233 BSBS38_00233 cynT cynT 209054 209581 + Carbonate dehydratase Belongs to the beta-class carbonic anhydrase family%3B KEGG: bli:BL05308 carbonic anhydrase gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00233 BSBS38_00234 BSBS38_00234 BSBS38_00234 209645 209935 + uncharacterized protein gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00234 BSBS38_00235 BSBS38_00235 BSBS38_00235 209993 210367 + uncharacterized protein gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00235 BSBS38_00236 BSBS38_00236 BSBS38_00236 210438 210782 + putative transcriptional regulatory protein YbdJ Member of the two-component regulatory system YbdK/YbdJ%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00236 BSBS38_00237 BSBS38_00237 BSBS38_00237 210779 211636 + Sensor histidine kinase YbdK Member of the two-component regulatory system YbdK/YbdJ. Probably activates YbdJ by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: ban:BA_3066 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00237 BSBS38_00238 BSBS38_00238 BSBS38_00238 211819 212082 + uncharacterized protein gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00238 BSBS38_00239 BSBS38_00239 BSBS38_00239 212067 212837 - Non-specific serine/threonine protein kinase Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bsu:BSU02030 serine/threonine protein kinase%2C bacterial gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00239 BSBS38_00240 BSBS38_00240 BSBS38_00240 212923 213780 - uncharacterized protein gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00240 BSBS38_00241 BSBS38_00241 BSBS38_00241 213912 215096 + uncharacterized protein gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00241 BSBS38_00242 BSBS38_00242 BSBS38_00242 215414 216802 + putative transporter YbxG Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00242 BSBS38_00243 BSBS38_00243 BSBS38_00243 216913 217161 + Sigma-G-dependent sporulation-specific SASP protein gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00243 BSBS38_00244 BSBS38_00244 BSBS38_00244 217178 217369 + uncharacterized protein gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00244 BSBS38_00245 BSBS38_00245 BSBS38_00245 217396 218199 - Beta-lactamase Belongs to the class-D beta-lactamase family%3B KEGG: bsu:BSU02090 beta-lactamase class D gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00245 BSBS38_00246 BSBS38_00246 BSBS38_00246 218374 219627 + Fatty-acid peroxygenase Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide%3B Belongs to the cytochrome P450 family%3B KEGG: bsu:BSU02100 fatty-acid peroxygenase gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00246 BSBS38_00247 BSBS38_00247 BSBS38_00247 219681 219911 - uncharacterized protein gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00247 BSBS38_00248 BSBS38_00248 BSBS38_00248 220161 221798 + putative amino acid-proton symporter YbeC Uptake of an yet unknown amino-acid with the concomitant import of a proton%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2. A. 3. 11) family gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00248 BSBS38_00249 BSBS38_00249 glpQ glpQ 221844 222725 - Glycerophosphodiester phosphodiesterase Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: bsu:BSU02130 glycerophosphoryl diester phosphodiesterase gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00249 BSBS38_00250 BSBS38_00250 BSBS38_00250 222824 224158 - Glycerol-3-phosphate transporter Responsible for glycerol-3-phosphate uptake. Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2. A. 1. 4) family gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00250 BSBS38_00251 BSBS38_00251 BSBS38_00251 224455 224703 + uncharacterized protein gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00251 BSBS38_00252 BSBS38_00252 yjgM yjgM 224795 225712 + Putative HTH-type DNA-binding domain-containing acetyltransferase YbfA Putative DNA-binding acetyltransferase%3B Contains 1 HTH marR-type DNA-binding domain%3B Contains 1 N-acetyltransferase domain%3B KEGG: bfb:VU15_08170 putative acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00252 BSBS38_00253 BSBS38_00253 BSBS38_00253 225709 226557 + putative MFS-type transporter YbfB Belongs to the major facilitator superfamily gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00253 BSBS38_00254 BSBS38_00254 BSBS38_00254 226650 226958 + putative MFS-type transporter YbfB Belongs to the major facilitator superfamily gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00254 BSBS38_00255 BSBS38_00255 BSBS38_00255 226993 227277 - uncharacterized protein gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00255 BSBS38_00256 BSBS38_00256 BSBS38_00256 227473 228384 - uncharacterized protein gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00256 BSBS38_00257 BSBS38_00257 BSBS38_00257 228473 230671 - uncharacterized protein Belongs to the FadG family gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00257 BSBS38_00258 BSBS38_00258 BSBS38_00258 230745 231665 - putative transporter YbhF Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00258 BSBS38_00259 BSBS38_00259 BSBS38_00259 231662 232489 - putative HTH-type transcriptional regulator YbfI Contains 1 HTH araC/xylS-type DNA-binding domain gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00259 BSBS38_00260 BSBS38_00260 BSBS38_00260 233682 234113 + hypothetical protein gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00260 BSBS38_00261 BSBS38_00261 BSBS38_00261 234288 234533 + putative 9.5 kDa protein in ORF3 5'region Belongs to the SPP1 holin family gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00261 BSBS38_00262 BSBS38_00262 lytE lytE 234930 236600 + putative N-acetylmuramidase Hydrolyzes the cell wall of L. lactis and M. lysodeikticus. Required for cell separation during growth. Belongs to the glycosyl hydrolase 73 family%3B Contains 3 LysM repeats%3B KEGG: bag:Bcoa_0529 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00262 BSBS38_00263 BSBS38_00263 BSBS38_00263 236710 237498 - putative lipoprotein YdeJ gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00263 BSBS38_00264 BSBS38_00264 purT purT 238759 239613 + Phosphoribosylglycinamide formyltransferase Catalyzes two reactions: the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate%2C ATP and beta GA%3B the second%2C a side reaction%2C is the production of acetyl phosphate and ADP from acetate and ATP. Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: bsu:BSU02230 phosphoribosylglycinamide formyltransferase 2 gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00264 BSBS38_00265 BSBS38_00265 BSBS38_00265 239622 239912 + Phosphoribosylglycinamide formyltransferase Catalyzes two reactions: the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate%2C ATP and beta GA%3B the second%2C a side reaction%2C is the production of acetyl phosphate and ADP from acetate and ATP%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: sers:SERRSCBI_13290 phosphoribosylglycinamide formyltransferase 2 gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00265 BSBS38_00266 BSBS38_00266 sspA sspA 240056 240997 + Glutamyl endopeptidase Belongs to the peptidase S1B family%3B KEGG: aau:AAur_1625 glutamyl endopeptidase gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00266 BSBS38_00267 BSBS38_00267 BSBS38_00267 240960 241343 + uncharacterized protein gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00267 BSBS38_00268 BSBS38_00268 BSBS38_00268 241528 241758 + Carboxylesterase Shows carboxylesterase activity in vitro%3B Belongs to the AB hydrolase superfamily gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00268 BSBS38_00269 BSBS38_00269 mhpC mhpC 241755 242417 + 2-hydroxy-6-oxonona-2%2C4-dienedioate hydrolase Shows carboxylesterase activity in vitro%3B Belongs to the AB hydrolase superfamily%3B KEGG: fri:FraEuI1c_5356 2-hydroxy-6-oxonona-2%2C4-dienedioate hydrolase gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00269 BSBS38_00270 BSBS38_00270 cho1 cho1 242613 243146 + CDP-diacylglycerol--serine O-phosphatidyltransferase Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: tcy:Thicy_0225 CDP-diacylglycerol---serine O-phosphatidyltransferase gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00270 BSBS38_00271 BSBS38_00271 phoA phoA 243137 243625 + Alkaline phosphatase Belongs to the DedA family%3B KEGG: bcl:ABC0731 alkaline phosphatase gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00271 BSBS38_00272 BSBS38_00272 pisD pisD 243618 244409 + Phosphatidylserine decarboxylase Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily%3B KEGG: bsu:BSU02290 phosphatidylserine decarboxylase gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00272 BSBS38_00273 BSBS38_00273 BSBS38_00273 244464 244742 + uncharacterized protein gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00273 BSBS38_00274 BSBS38_00274 BSBS38_00274 244847 246187 + Putative hydrolase YbfO KEGG: bsr:I33_0270 erythromycin esterase%3B Carboxylic ester hydrolases gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00274 BSBS38_00275 BSBS38_00275 BSBS38_00275 246295 247182 + putative HTH-type transcriptional regulator YbfP Probable transcriptional regulator%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00275 BSBS38_00276 BSBS38_00276 BSBS38_00276 247382 248350 + UPF0176 protein Belongs to the UPF0176 family%3B Contains 1 rhodanese domain gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00276 BSBS38_00277 BSBS38_00277 BSBS38_00277 248386 249630 - C4-dicarboxylate transport protein Responsible for the transport of dicarboxylates such as succinate%2C fumarate%2C and malate across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00277 BSBS38_00278 BSBS38_00278 gamP gamP 249775 251670 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity). This system may be involved in glucosamine transport%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU02350 PTS system%2C D-glucosamine-specific IIA component gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00278 BSBS38_00279 BSBS38_00279 nagB nagB 251691 252440 - Glucosamine-6-phosphate deaminase Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion%3B Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily%3B KEGG: bsu:BSU02360 glucosamine-6-phosphate deaminase gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00279 BSBS38_00280 BSBS38_00280 BSBS38_00280 252653 253360 + putative HTH-type transcriptional regulator YbgA Contains 1 HTH gntR-type DNA-binding domain gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00280 BSBS38_00281 BSBS38_00281 BSBS38_00281 253394 253669 + putative membrane protein YbgB gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00281 BSBS38_00282 BSBS38_00282 ilvE ilvE 253879 254949 + Branched-chain-amino-acid transaminase Transaminates branched-chain amino acids and ketoglutarate. Involved in the final step of the methionine regeneration pathway%2C where ketomethiobutyrate (KMTB) is converted to methionine via a transamination. The amino donor preference is isoleucine%2C leucine%2C valine%2C phenylalanine%2C and tyrosine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU02390 branched-chain amino acid aminotransferase gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00282 BSBS38_00283 BSBS38_00283 BSBS38_00283 254986 256398 - putative amino acid permease YbgF Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00283 BSBS38_00284 BSBS38_00284 mmuM mmuM 256518 257465 - Homocysteine S-methyltransferase Contains 1 Hcy-binding domain%3B KEGG: smul:SMUL_1220 homocysteine S-methyltransferase gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00284 BSBS38_00285 BSBS38_00285 BSBS38_00285 257594 257803 - putative sodium/glutamine symporter GlnT Probably functions as a sodium/glutamine symporter for glutamine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00285 BSBS38_00286 BSBS38_00286 BSBS38_00286 257816 259030 - putative sodium/glutamine symporter GlnT Probably functions as a sodium/glutamine symporter for glutamine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00286 BSBS38_00287 BSBS38_00287 glsA glsA 259053 260036 - Glutaminase Belongs to the glutaminase family%3B KEGG: bsu:BSU02430 glutaminase gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00287 BSBS38_00288 BSBS38_00288 ycbA ycbA 260218 261570 + Histidine kinase Member of the two-component regulatory system GlnK/GlnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. Probably activates GlnL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsut:BSUB_00292 two-component system%2C sensor histidine kinase YcbA gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00288 BSBS38_00289 BSBS38_00289 BSBS38_00289 261581 262525 + Transcriptional regulatory protein GlnL Member of the two-component regulatory system GlnL/GlnK that positively regulates the expression of the glsA-glnT operon in response to glutamine. GlnL binds the promoter region of glsA- glnT in vitro%3B Contains 1 response regulatory domain gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00289 BSBS38_00290 BSBS38_00290 kdgD kdgD 262752 263678 + 5-dehydro-4-deoxyglucarate dehydratase Belongs to the DapA family%3B KEGG: bsu:BSU02460 5-dehydro-4-deoxyglucarate dehydratase gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00290 BSBS38_00291 BSBS38_00291 BSBS38_00291 263675 265174 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bsut:BSUB_00295 aldehyde dehydrogenase (NAD+) gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00291 BSBS38_00292 BSBS38_00292 BSBS38_00292 265259 266626 + putative glucarate transporter Uptake of D-glucarate. Belongs to the major facilitator superfamily. Phthalate permease family gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00292 BSBS38_00293 BSBS38_00293 gudD gudD 266663 268030 + Glucarate dehydratase Catalyzes the dehydration of glucarate to 5-keto-4- deoxy-D-glucarate (5-kdGluc)%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily%3B KEGG: bsu:BSU02490 glucarate dehydratase gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00293 BSBS38_00294 BSBS38_00294 BSBS38_00294 268100 268801 + putative HTH-type transcriptional regulator YcbG Contains 1 HTH gntR-type DNA-binding domain gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00294 BSBS38_00295 BSBS38_00295 garD garD 268893 270425 + Galactarate dehydratase Catalyzes the dehydration of galactarate to form 5- dehydro-4-deoxy-D-glucarate%3B Belongs to the UxaA family%3B KEGG: bsu:BSU02510 galactarate dehydratase gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00295 BSBS38_00296 BSBS38_00296 BSBS38_00296 270699 271619 + uncharacterized protein Belongs to the aminoglycoside phosphotransferase family gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00296 BSBS38_00297 BSBS38_00297 BSBS38_00297 272021 272182 + Tryptophan RNA-binding attenuator protein inhibitory protein gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00297 BSBS38_00298 BSBS38_00298 BSBS38_00298 272203 273141 + putative transporter YcbK Belongs to the EamA transporter family%3B Contains 1 EamA domain gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00298 BSBS38_00299 BSBS38_00299 BSBS38_00299 273226 273918 + Response regulator ArlR Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00299 BSBS38_00300 BSBS38_00300 kdpD kdpD 273920 274855 + Histidine kinase Member of the two-component regulatory system YcbM/YcbL. Probably activates YcbL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: panp:PSNIH2_18265 two-component system%2C OmpR family%2C sensor histidine kinase KdpD gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00300 BSBS38_00301 BSBS38_00301 BSBS38_00301 274947 275870 + putative ABC transporter ATP-binding protein YcbN Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00301 BSBS38_00302 BSBS38_00302 BSBS38_00302 275889 276575 + uncharacterized protein gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00302 BSBS38_00303 BSBS38_00303 BSBS38_00303 276630 277016 - uncharacterized protein gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00303 BSBS38_00304 BSBS38_00304 cwlJ cwlJ 277329 277757 + N-acetylmuramoyl-L-alanine amidase Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination%3B Belongs to the CwlJ family%3B KEGG: bsu:BSU02600 N-acetylmuramoyl-L-alanine amidase gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00304 BSBS38_00305 BSBS38_00305 BSBS38_00305 277863 278594 + uncharacterized protein Contains 1 VWFA domain gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00305 BSBS38_00306 BSBS38_00306 phoD phoD 278871 280622 + Alkaline phosphatase Belongs to the PhoD family%3B KEGG: bsu:BSU02620 alkaline phosphatase D gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00306 BSBS38_00307 BSBS38_00307 BSBS38_00307 280635 280847 + Sec-independent protein translocase protein TatAd Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for PhoD secretion. The cytosolic fraction of TatAd binds the precursor of PhoD%3B Belongs to the TatA/E family gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00307 BSBS38_00308 BSBS38_00308 BSBS38_00308 280908 281636 + Sec-independent protein translocase protein TatCd Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance%3B Belongs to the TatC family gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00308 BSBS38_00309 BSBS38_00309 BSBS38_00309 281633 282280 - Pyroglutamyl-peptidase I Removes 5-oxoproline from various penultimate amino acid residues except L-proline. Belongs to the peptidase C15 family%3B KEGG: bsu:BSU02650 pyroglutamyl-peptidase gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00309 BSBS38_00310 BSBS38_00310 iscS iscS 282359 282937 + Cysteine desulfurase Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: saz:Sama_1293 cysteine desulfurase gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00310 BSBS38_00311 BSBS38_00311 BSBS38_00311 282934 283470 + putative aminotransferase YcbU Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00311 BSBS38_00312 BSBS38_00312 BSBS38_00312 283512 284945 - Lincomycin resistance protein LmrB Proton-dependent transporter. May mediate the efflux of lincomycin. Belongs to the major facilitator superfamily. EmrB family gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00312 BSBS38_00313 BSBS38_00313 BSBS38_00313 284990 285556 - HTH-type transcriptional regulator LmrA Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons%3B Contains 1 HTH tetR-type DNA-binding domain gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00313 BSBS38_00314 BSBS38_00314 ansA ansA 285773 286900 + Asparaginase Catalyzes the conversion of L-asparagine to L-aspartate and ammonium%3B Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: bsu:BSU02690 L-asparaginase gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00314 BSBS38_00315 BSBS38_00315 BSBS38_00315 287062 287700 + Triacylglycerol lipase Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups%3B Belongs to the AB hydrolase superfamily%3B KEGG: bsu:BSU02700 triacylglycerol lipase gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00315 BSBS38_00316 BSBS38_00316 BSBS38_00316 287738 288121 - uncharacterized protein gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00316 BSBS38_00317 BSBS38_00317 BSBS38_00317 288356 289432 + uncharacterized protein gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00317 BSBS38_00318 BSBS38_00318 natK natK 289471 290427 - Histidine kinase Member of the two-component regulatory system NatK/NatR that positively regulates the expression of the natAB operon. Potentially phosphorylates NatR%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU02730 two-component system%2C LytT family%2C sensor histidine kinase NatK gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00318 BSBS38_00319 BSBS38_00319 BSBS38_00319 290440 291141 - Transcriptional regulatory protein NatR Member of the two-component regulatory system NatK/NatR that positively regulates the expression of the natAB operon. Acts by binding directly to the promoter of natAB%3B Contains 1 HTH LytTR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00319 BSBS38_00320 BSBS38_00320 BSBS38_00320 291286 292026 + ABC transporter ATP-binding protein NatA Part of an ABC transporter that catalyzes ATP-dependent electrogenic sodium extrusion%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00320 BSBS38_00321 BSBS38_00321 BSBS38_00321 292027 293187 + ABC transporter permease protein NatB Part of an ABC transporter that catalyzes ATP-dependent electrogenic sodium extrusion gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00321 BSBS38_00322 BSBS38_00322 iolS iolS 293323 294255 + putative oxidoreductase YccK Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: bay:RBAM_036800 myo-inositol catabolism protein IolS%3B With NAD(+) or NADP(+) as acceptor gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00322 BSBS38_00323 BSBS38_00323 BSBS38_00323 294295 294651 - putative lipoprotein YcdA gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00323 BSBS38_00324 BSBS38_00324 BSBS38_00324 294741 295310 - putative lipoprotein YcdA gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00324 BSBS38_00325 BSBS38_00325 BSBS38_00325 295687 297108 + uncharacterized protein To B. subtilis YcdC gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00325 BSBS38_00326 BSBS38_00326 BSBS38_00326 297157 298656 + uncharacterized protein To B. subtilis YcdB gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00326 BSBS38_00327 BSBS38_00327 cwlK cwlK 298664 299167 - Peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK Cleaves the linkage of the L-alanine-D-glutamic acid of B. subtilis cell wall. Belongs to the peptidase M15C family%3B KEGG: bsu:BSU02810 peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK%3B Acting on peptide bonds (peptidases) gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00327 BSBS38_00328 BSBS38_00328 rapJ rapJ 299290 300411 + Response regulator aspartate phosphatase J Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bsu:BSU02820 response regulator aspartate phosphatase J%3B Acting on ester bonds gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00328 BSBS38_00329 BSBS38_00329 BSBS38_00329 300519 301295 + Glucose 1-dehydrogenase (NAD(P)(+)) May play some role in spore germination. Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU02830 glucose 1-dehydrogenase gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00329 BSBS38_00330 BSBS38_00330 BSBS38_00330 301320 303005 + Oligo-1%2C6-glucosidase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bsu:BSU02840 oligo-1%2C6-glucosidase gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00330 BSBS38_00331 BSBS38_00331 BSBS38_00331 303192 304151 + High-affinity zinc uptake system binding-protein ZnuA Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). ZnuABC-mediated zinc transport is required for comF expression and competence development%3B Belongs to the bacterial solute-binding protein 9 family gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00331 BSBS38_00332 BSBS38_00332 BSBS38_00332 304206 304901 + Polar-amino-acid-transporting ATPase Has a role in exoprotein production%2C sporulation and competence. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: eic:NT01EI_3692 polar amino acid transport system ATP-binding protein gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00332 BSBS38_00333 BSBS38_00333 BSBS38_00333 304859 305701 + High-affinity zinc uptake system membrane protein ZnuB Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for the translocation of the substrate across the membrane (By similarity). ZnuABC-mediated zinc transport is required for comF expression and competence development%3B Belongs to the ABC-3 integral membrane protein family gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00333 BSBS38_00334 BSBS38_00334 BSBS38_00334 305739 306734 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00334 BSBS38_00335 BSBS38_00335 BSBS38_00335 307018 307617 + General stress protein 16U Belongs to the CAPAB/TerDEXZ family gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00335 BSBS38_00336 BSBS38_00336 BSBS38_00336 307639 308220 + General stress protein 16U Belongs to the CAPAB/TerDEXZ family gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00336 BSBS38_00337 BSBS38_00337 BSBS38_00337 308255 308833 + uncharacterized protein Belongs to the CAPAB/TerDEXZ family gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00337 BSBS38_00338 BSBS38_00338 BSBS38_00338 308885 309658 + putative membrane protein YceF Belongs to the TerC family gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00338 BSBS38_00339 BSBS38_00339 BSBS38_00339 309742 311355 + uncharacterized protein gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00339 BSBS38_00340 BSBS38_00340 BSBS38_00340 311371 312462 + uncharacterized protein Belongs to the TelA family gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00340 BSBS38_00341 BSBS38_00341 BSBS38_00341 312579 312911 + hypothetical protein gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00341 BSBS38_00342 BSBS38_00342 BSBS38_00342 312929 313729 + putative transposase-like protein Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00342 BSBS38_00343 BSBS38_00343 BSBS38_00343 313874 315076 + Putative niacin/nicotinamide transporter NaiP Probably involved in the uptake of amidated and deamidated forms of niacin. Increases the growth rate of E. coli that is unable to make niacin de nov%3B confers increased sensitivity to the toxic niacin analog 6-amino-nicotinamide to wild-type E. coli. There is probably another mechanism for niacin uptake. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00343 BSBS38_00344 BSBS38_00344 BSBS38_00344 315288 316460 - putative MFS-type transporter YceJ Belongs to the major facilitator superfamily gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00344 BSBS38_00345 BSBS38_00345 BSBS38_00345 316529 316816 - putative HTH-type transcriptional regulator YceK Contains 1 HTH arsR-type DNA-binding domain gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00345 BSBS38_00346 BSBS38_00346 proV proV 317093 318349 + Quaternary-amine-transporting ATPase Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: bsu:BSU02980 glycine betaine/proline transport system ATP-binding protein gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00346 BSBS38_00347 BSBS38_00347 BSBS38_00347 318351 319199 + Glycine betaine transport system permease protein OpuAB Involved in a multicomponent binding-protein-dependent transport system for glycine betain%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00347 BSBS38_00348 BSBS38_00348 BSBS38_00348 319199 320080 + Glycine betaine-binding protein OpuAC Involved in a multicomponent binding-protein-dependent transport system for glycine betaine gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00348 BSBS38_00349 BSBS38_00349 amhX amhX 320118 321269 - Amidohydrolase AmhX Belongs to the peptidase M20 family%3B KEGG: bsu:BSU03010 amidohydrolase%3B In linear amides gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00349 BSBS38_00350 BSBS38_00350 BSBS38_00350 321419 322852 + uncharacterized protein To E. coli YfcC and H. influenzae HI_0594 gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00350 BSBS38_00351 BSBS38_00351 BSBS38_00351 322968 323522 + uncharacterized protein gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00351 BSBS38_00352 BSBS38_00352 amyA amyA 323709 325142 + Alpha-amylase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bsu:BSU03040 alpha-amylase%3B overlaps another CDS with the same product name gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00352 BSBS38_00353 BSBS38_00353 BSBS38_00353 325105 325656 + Alpha-amylase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bss:BSUW23_01555 alpha-amylase%3B overlaps another CDS with the same product name gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00353 BSBS38_00354 BSBS38_00354 BSBS38_00354 325676 325807 - hypothetical protein gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00354 BSBS38_00355 BSBS38_00355 BSBS38_00355 325812 327164 - hypothetical protein gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00355 BSBS38_00356 BSBS38_00356 BSBS38_00356 327414 328379 + L-lactate dehydrogenase Belongs to the LDH/MDH superfamily. LDH family%3B KEGG: bsu:BSU03050 L-lactate dehydrogenase gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00356 BSBS38_00357 BSBS38_00357 BSBS38_00357 328411 330036 + L-lactate permease May play a role in L-lactate transport. Belongs to the lactate permease family gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00357 BSBS38_00358 BSBS38_00358 BSBS38_00358 330379 331140 + uncharacterized protein Belongs to the DcsA family gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00358 BSBS38_00359 BSBS38_00359 BSBS38_00359 331256 331759 - putative transporter YcgH Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00359 BSBS38_00360 BSBS38_00360 BSBS38_00360 332696 333196 + uncharacterized protein gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00360 BSBS38_00361 BSBS38_00361 nadE nadE 333326 334144 + NAD(+) synthase Belongs to the NAD synthetase family%3B KEGG: bsu:BSU03130 NAD+ synthase gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00361 BSBS38_00362 BSBS38_00362 BSBS38_00362 334271 334786 - Tunicamycin resistance protein gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00362 BSBS38_00363 BSBS38_00363 aroK aroK 335063 335437 + Shikimate kinase Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate%3B Belongs to the shikimate kinase family%3B KEGG: bsu:BSU03150 shikimate kinase%3B overlaps another CDS with the same product name gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00363 BSBS38_00364 BSBS38_00364 BSBS38_00364 335383 335622 + Shikimate kinase Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate%3B Belongs to the shikimate kinase family%3B KEGG: bsu:BSU03150 shikimate kinase%3B overlaps another CDS with the same product name gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00364 BSBS38_00365 BSBS38_00365 BSBS38_00365 335650 336411 - putative methyltransferase YcgJ Belongs to the methyltransferase superfamily gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00365 BSBS38_00366 BSBS38_00366 BSBS38_00366 336528 337502 + putative HTH-type transcriptional regulator YcgK Contains 1 HTH lysR-type DNA-binding domain gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00366 BSBS38_00367 BSBS38_00367 BSBS38_00367 337574 338530 + Cephalosporin-C deacetylase Esterase that removed acetyl groups from a number of O- acetylated small substrates%2C such as acetylated xylose%2C short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages%3B Belongs to the carbohydrate esterase 7 family%3B KEGG: bsu:BSU03180 cephalosporin-C deacetylase gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00367 BSBS38_00368 BSBS38_00368 BSBS38_00368 338616 339398 + uncharacterized protein gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00368 BSBS38_00369 BSBS38_00369 BSBS38_00369 339588 340499 + Proline dehydrogenase Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C)%3B Belongs to the proline dehydrogenase family%3B KEGG: bsu:BSU03200 proline dehydrogenase%3B Acting on the CH-NH group of donors gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00369 BSBS38_00370 BSBS38_00370 BSBS38_00370 340516 342063 + L-glutamate gamma-semialdehyde dehydrogenase Belongs to the aldehyde dehydrogenase family. RocA subfamily%3B KEGG: bsu:BSU03210 1-pyrroline-5-carboxylate dehydrogenase gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00370 BSBS38_00371 BSBS38_00371 BSBS38_00371 342178 343608 + Sodium/proline symporter Catalyzes the sodium-dependent uptake of extracellular L-proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00371 BSBS38_00372 BSBS38_00372 BSBS38_00372 343761 344996 + Proline-responsive transcriptional activator PutR Activates transcription of the putBCP operon. Requires proline as a coactivator%3B Belongs to the CdaR family gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00372 BSBS38_00373 BSBS38_00373 BSBS38_00373 345033 345890 - UPF0703 protein YcgQ Belongs to the UPF0703 family gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00373 BSBS38_00374 BSBS38_00374 BSBS38_00374 345895 346779 - UPF0718 protein YcgR Belongs to the UPF0718 family gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00374 BSBS38_00375 BSBS38_00375 ybfF ybfF 346879 347733 - putative hydrolase Belongs to the AB hydrolase superfamily%3B KEGG: she:Shewmr4_2033 esterase%3B Acting on ester bonds gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00375 BSBS38_00376 BSBS38_00376 trxB trxB 347896 348906 + Thioredoxin-disulfide reductase Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bsu:BSU03270 thioredoxin reductase (NADPH) gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00376 BSBS38_00377 BSBS38_00377 BSBS38_00377 348938 350383 - Uroporphyrinogen-III C-methyltransferase Belongs to the precorrin methyltransferase family%3B KEGG: bsu:BSU03280 uroporphyrinogen III methyltransferase / synthase gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00377 BSBS38_00378 BSBS38_00378 nirD nirD 350450 350770 - Nitrite reductase (NADH) Required for nitrite assimilation. Required for activity of the reductase (By similarity)%3B Contains 1 Rieske domain%3B KEGG: bsu:BSU03290 nitrite reductase (NADH) small subunit gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00378 BSBS38_00379 BSBS38_00379 nirB nirB 350802 353219 - Nitrite reductase (NADH) Required for nitrite assimilation%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bsu:BSU03300 nitrite reductase (NADH) large subunit gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00379 BSBS38_00380 BSBS38_00380 nasA nasA 353340 355472 - Nitrate reductase Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants%2C fungi and bacteria. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU03310 assimilatory nitrate reductase catalytic subunit gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00380 BSBS38_00381 BSBS38_00381 BSBS38_00381 355479 357794 - Nitrite reductase (NADH) Required for nitrate assimilation%3B KEGG: mmt:Metme_3418 nitrite reductase (NADH) large subunit gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00381 BSBS38_00382 BSBS38_00382 BSBS38_00382 357974 359179 + Nitrate transporter May function as a nitrate transporter%3B Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00382 BSBS38_00383 BSBS38_00383 gch4 gch4 359296 360210 + GTP cyclohydrolase I Converts GTP to 7%2C8-dihydroneopterin triphosphate%3B Belongs to the GTP cyclohydrolase IV family%3B KEGG: bsu:BSU03340 GTP cyclohydrolase I gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00383 BSBS38_00384 BSBS38_00384 BSBS38_00384 360207 360791 + Serine-type D-Ala-D-Ala carboxypeptidase Belongs to the YkuD family%3B KEGG: ljn:T285_08130 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00384 BSBS38_00385 BSBS38_00385 BSBS38_00385 361230 362423 + COBW domain-containing protein Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00385 BSBS38_00386 BSBS38_00386 BSBS38_00386 362471 363151 - putative amino-acid ABC transporter permease protein YckA Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00386 BSBS38_00387 BSBS38_00387 BSBS38_00387 363161 364024 - putative ABC transporter extracellular-binding protein YckB Probably part of a binding-protein-dependent transport system. Belongs to the bacterial solute-binding protein 3 family gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00387 BSBS38_00388 BSBS38_00388 BSBS38_00388 364195 364296 + hypothetical protein gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00388 BSBS38_00389 BSBS38_00389 BSBS38_00389 364293 364382 + hypothetical protein gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00389 BSBS38_00390 BSBS38_00390 BSBS38_00390 364402 364857 + uncharacterized protein gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00390 BSBS38_00391 BSBS38_00391 BSBS38_00391 364939 365271 + uncharacterized protein gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00391 BSBS38_00392 BSBS38_00392 BSBS38_00392 365399 365821 + putative HTH-type transcriptional regulator YfiV Contains 1 HTH marR-type DNA-binding domain gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00392 BSBS38_00393 BSBS38_00393 BSBS38_00393 365809 366129 + hypothetical protein gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00393 BSBS38_00394 BSBS38_00394 BSBS38_00394 366148 366768 + hypothetical protein gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00394 BSBS38_00395 BSBS38_00395 BSBS38_00395 366719 366892 + hypothetical protein gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00395 BSBS38_00396 BSBS38_00396 bglA bglA 366965 368398 + 6-phospho-beta-glucosidase Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bso:BSNT_00608 6-phospho-beta-glucosidase gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00396 BSBS38_00397 BSBS38_00397 BSBS38_00397 368435 368833 - DNA-entry nuclease inhibitor gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00397 BSBS38_00398 BSBS38_00398 BSBS38_00398 368860 369309 - DNA-entry nuclease By degrading DNA that enters the cell%2C plays a role in the competence of cells to be transformed. Degrades both double- stranded%2C linear and covalently closed circular DNA. To B. subtilis NucB gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00398 BSBS38_00399 BSBS38_00399 BSBS38_00399 369477 370127 - Methyl-accepting chemotaxis protein TlpC Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00399 BSBS38_00400 BSBS38_00400 BSBS38_00400 370308 371198 - Methyl-accepting chemotaxis protein TlpC Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00400 BSBS38_00401 BSBS38_00401 hxlB hxlB 371309 371866 - 6-phospho-3-hexuloisomerase Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate. Together with HxlA%2C may act as a formaldehyde detoxification system. Belongs to the SIS family. PHI subfamily%3B Contains 1 SIS domain%3B KEGG: bsu:BSU03450 6-phospho-3-hexuloisomerase gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00401 BSBS38_00402 BSBS38_00402 hxlA hxlA 371872 372504 - 3-hexulose-6-phosphate synthase Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate%3B Belongs to the HPS/KGPDC family. HPS subfamily%3B KEGG: eum:ECUMN_2963 3-hexulose-6-phosphate synthase gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00402 BSBS38_00403 BSBS38_00403 BSBS38_00403 372732 373094 + HTH-type transcriptional activator HxlR Positive regulator of hxlAB expression. Contains 1 HTH hxlR-type DNA-binding domain gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00403 BSBS38_00404 BSBS38_00404 BSBS38_00404 373668 384431 + Surfactin synthase subunit This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu%2C Glu%2C Asp and Val. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00404 BSBS38_00405 BSBS38_00405 BSBS38_00405 384444 395195 + Surfactin synthase subunit This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu%2C Glu%2C Asp and Val. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00405 BSBS38_00406 BSBS38_00406 BSBS38_00406 395232 399059 + Surfactin synthase subunit Probably activates a leucine. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 1 acyl carrier domain gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00406 BSBS38_00407 BSBS38_00407 BSBS38_00407 399088 399816 + Surfactin synthase thioesterase subunit Probable thioesterase involved in the biosynthesis of surfactin. Belongs to the thioesterase family gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00407 BSBS38_00408 BSBS38_00408 BSBS38_00408 399918 401144 + putative MFS-type transporter YcxA Belongs to the major facilitator superfamily gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00408 BSBS38_00409 BSBS38_00409 BSBS38_00409 401159 401716 - uncharacterized protein gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00409 BSBS38_00410 BSBS38_00410 BSBS38_00410 401770 402708 - putative transporter YcxC Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00410 BSBS38_00411 BSBS38_00411 BSBS38_00411 402832 404166 + putative HTH-type transcriptional regulator YcxD In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00411 BSBS38_00412 BSBS38_00412 lys5 lys5 404161 404835 - 4'-phosphopantetheinyl transferase ffp May activate the peptidyl carrier protein (PCP) domains of fengycin synthase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family%3B KEGG: bsr:I33_0409 4'-phosphopantetheinyl transferase%3B Transferases for other substituted phosphate groups gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00412 BSBS38_00413 BSBS38_00413 BSBS38_00413 404940 405587 - putative membrane protein YczE gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00413 BSBS38_00414 BSBS38_00414 BSBS38_00414 405908 406651 - Fe(3+) ions import ATP-binding protein FbpC Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3. A. 1. 10) family%3B Contains 1 ABC transporter domain gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00414 BSBS38_00415 BSBS38_00415 BSBS38_00415 406665 407369 - L-cystine transport system permease protein TcyB Part of the ABC transporter complex TcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00415 BSBS38_00416 BSBS38_00416 BSBS38_00416 407356 408162 - L-cystine-binding protein TcyA Part of the ABC transporter complex TcyABC involved in L-cystine import%3B Belongs to the bacterial solute-binding protein 3 family gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00416 BSBS38_00417 BSBS38_00417 BSBS38_00417 408278 409150 - HTH-type transcriptional regulator BsdA Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00417 BSBS38_00418 BSBS38_00418 ubiX ubiX 409240 409854 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase C (By similarity). Involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions (PubMed:18388975)%3B Belongs to the UbiX/PAD1 family. YclB subfamily%3B KEGG: bsu:BSU03630 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00418 BSBS38_00419 BSBS38_00419 ubiD ubiD 409857 411278 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives%3B Belongs to the UbiD family. YclC subfamily%3B KEGG: sul:SYO3AOP1_0556 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00419 BSBS38_00420 BSBS38_00420 BSBS38_00420 411295 411522 + Phenolic acid decarboxylase subunit Part of the BsdBCD complex involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00420 BSBS38_00421 BSBS38_00421 BSBS38_00421 411519 411788 + uncharacterized protein gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00421 BSBS38_00422 BSBS38_00422 BSBS38_00422 412048 412893 + Prolyl aminopeptidase Belongs to the AB hydrolase superfamily%3B KEGG: bsus:Q433_02185 proline iminopeptidase gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00422 BSBS38_00423 BSBS38_00423 BSBS38_00423 412934 414412 - putative transporter YclF Belongs to the PTR2/POT transporter (TC 2. A. 17) family gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00423 BSBS38_00424 BSBS38_00424 BSBS38_00424 414682 414906 + uncharacterized protein Contains 11 PbH1 repeats%3B overlaps another CDS with the same product name gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00424 BSBS38_00425 BSBS38_00425 BSBS38_00425 414903 416435 + uncharacterized protein Contains 11 PbH1 repeats%3B overlaps another CDS with the same product name gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00425 BSBS38_00426 BSBS38_00426 BSBS38_00426 416450 416671 - uncharacterized protein gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00426 BSBS38_00427 BSBS38_00427 BSBS38_00427 416797 418431 + Spore germination protein KA Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKA family gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00427 BSBS38_00428 BSBS38_00428 BSBS38_00428 418421 419644 + Spore germination protein KC Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKC lipoprotein family gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00428 BSBS38_00429 BSBS38_00429 BSBS38_00429 419669 420790 + Spore germination protein KB Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00429 BSBS38_00430 BSBS38_00430 BSBS38_00430 420895 421575 - putative ABC transporter ATP-binding protein YclH Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00430 BSBS38_00431 BSBS38_00431 BSBS38_00431 421591 423057 - putative ABC transporter permease YclI Belongs to the ABC-4 integral membrane protein family gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00431 BSBS38_00432 BSBS38_00432 BSBS38_00432 423270 423953 + Cell cycle transcriptional regulator CtrA Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle%2C including cell division%2C stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA replication%2C DNA methylation%2C and class II flagellar biogenesis. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00432 BSBS38_00433 BSBS38_00433 vicK vicK 423943 425361 + Histidine kinase Could be member of the two-component regulatory system YclK/YclJ. Potentially phosphorylates YclJ%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bco:Bcell_4305 two-component system%2C OmpR family%2C sensor histidine kinase VicK gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00433 BSBS38_00434 BSBS38_00434 rapC rapC 425524 426672 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bsu:BSU03770 response regulator aspartate phosphatase C%3B Acting on ester bonds gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00434 BSBS38_00435 BSBS38_00435 BSBS38_00435 426656 426778 + Phosphatase RapC inhibitor Inhibitor of the activity of phosphatase RapC. Belongs to the phr family gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00435 BSBS38_00436 BSBS38_00436 BSBS38_00436 427048 427161 - UPF0752 membrane protein YczN Belongs to the UPF0752 family gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00436 BSBS38_00437 BSBS38_00437 lysC lysC 427314 428678 - Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: bsu:BSU03790 aspartate kinase gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00437 BSBS38_00438 BSBS38_00438 BSBS38_00438 428802 428909 + hypothetical protein gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00438 BSBS38_00439 BSBS38_00439 BSBS38_00439 429069 430019 + putative ABC transporter permease protein YclN Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00439 BSBS38_00440 BSBS38_00440 BSBS38_00440 430012 430959 + putative ABC transporter permease protein YclO Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00440 BSBS38_00441 BSBS38_00441 BSBS38_00441 430953 431711 + Autoinducer 2 import ATP-binding protein LsrA Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3. A. 1. 2. 8) family%3B Contains 2 ABC transporter domains gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00441 BSBS38_00442 BSBS38_00442 BSBS38_00442 431733 432686 + putative ABC transporter solute-binding protein YclQ Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00442 BSBS38_00443 BSBS38_00443 BSBS38_00443 432916 433848 + hypothetical protein gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00443 BSBS38_00444 BSBS38_00444 BSBS38_00444 433895 435313 - putative MFS-type transporter YcnB Belongs to the major facilitator superfamily. EmrB family gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00444 BSBS38_00445 BSBS38_00445 BSBS38_00445 435333 436211 - putative HTH-type transcriptional regulator YcnC Contains 1 HTH tetR-type DNA-binding domain gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00445 BSBS38_00446 BSBS38_00446 BSBS38_00446 436375 437124 - FMN reductase (NAD(P)H) Reduces FMNH(2) to FMN%2C with NADH or NADPH as reductant. It also reduces nitroaromatic compounds%2C quinones%2C chromates and azo dyes. It could supply the reduced form of FMN to luciferase- like protein and contribute to the degradation of aromatic compounds%3B Belongs to the flavin oxidoreductase frp family%3B KEGG: bsu:BSU03860 FMN reductase (NAD(P)H) gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00446 BSBS38_00447 BSBS38_00447 BSBS38_00447 437141 437428 - Putative monooxygenase YcnE Putative monooxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the LsrG family%3B Contains 1 ABM domain gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00447 BSBS38_00448 BSBS38_00448 BSBS38_00448 437568 437882 + putative HTH-type transcriptional regulator YczG Contains 1 HTH arsR-type DNA-binding domain gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00448 BSBS38_00449 BSBS38_00449 BSBS38_00449 437884 439323 - HTH-type transcriptional regulatory protein GabR Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00449 BSBS38_00450 BSBS38_00450 gabT gabT 439429 440739 + 4-aminobutyrate--2-oxoglutarate transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU03900 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00450 BSBS38_00451 BSBS38_00451 gabD gabD 440808 442196 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU03910 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00451 BSBS38_00452 BSBS38_00452 BSBS38_00452 442319 442897 + Glucose uptake protein GlcU Involved in the uptake of glucose%3B Belongs to the GRP transporter (TC 2. A. 7. 5) family gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00452 BSBS38_00453 BSBS38_00453 BSBS38_00453 442984 443181 + putative glucose uptake protein Involved in the uptake of glucose%3B Belongs to the GRP transporter (TC 2. A. 7. 5) family gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00453 BSBS38_00454 BSBS38_00454 fabG fabG 443201 443986 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: mam:Mesau_02128 3-oxoacyl-(acyl-carrier protein) reductase gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00454 BSBS38_00455 BSBS38_00455 BSBS38_00455 444030 444644 - uncharacterized protein gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00455 BSBS38_00456 BSBS38_00456 BSBS38_00456 444657 446282 - Copper transport protein YcnJ Involved in uptake of extracellular oxidized copper under copper-limiting conditions%3B In the N-terminal sectio%3B belongs to the CopC family%3B In the C-terminal sectio%3B belongs to the CopD family gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00456 BSBS38_00457 BSBS38_00457 BSBS38_00457 446317 446889 - HTH-type transcriptional repressor YcnK May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor%3B Contains 1 HTH deoR-type DNA-binding domain gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00457 BSBS38_00458 BSBS38_00458 BSBS38_00458 447054 447407 + uncharacterized protein gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00458 BSBS38_00459 BSBS38_00459 mtlA mtlA 447580 449016 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bsu:BSU03981 PTS system%2C mannitol-specific IIB component gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00459 BSBS38_00460 BSBS38_00460 BSBS38_00460 449041 449472 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B KEGG: bsu:BSU03982 PTS system%2C mannitol-specific IIA component gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00460 BSBS38_00461 BSBS38_00461 mtlD mtlD 449474 450595 + Mannitol-1-phosphate 5-dehydrogenase Belongs to the mannitol dehydrogenase family%3B KEGG: eco:b3600 mannitol-1-phosphate 5-dehydrogenase gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00461 BSBS38_00462 BSBS38_00462 ttuC ttuC 450692 451750 + Tartrate dehydrogenase Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: bsu:BSU04000 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00462 BSBS38_00463 BSBS38_00463 BSBS38_00463 451769 452011 + hypothetical protein gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00463 BSBS38_00464 BSBS38_00464 lepB lepB 452022 452447 + Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bsu:BSU04010 signal peptidase I gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00464 BSBS38_00465 BSBS38_00465 BSBS38_00465 452507 453115 - uncharacterized protein Belongs to the dienelactone hydrolase family gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00465 BSBS38_00466 BSBS38_00466 fabZ fabZ 453203 453595 + 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bsr:I33_0464 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00466 BSBS38_00467 BSBS38_00467 BSBS38_00467 453628 453792 - uncharacterized protein gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00467 BSBS38_00468 BSBS38_00468 BSBS38_00468 453925 454674 + Putative phosphatase YcsE Belongs to the HAD-like hydrolase superfamily. Cof family gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00468 BSBS38_00469 BSBS38_00469 BSBS38_00469 454880 455653 + UPF0271 protein Belongs to the UPF0271 (lamB) family gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00469 BSBS38_00470 BSBS38_00470 BSBS38_00470 455668 456882 + putative membrane protein YcsG Belongs to the NRAMP family gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00470 BSBS38_00471 BSBS38_00471 BSBS38_00471 456888 457679 + UPF0317 protein Belongs to the UPF0317 family gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00471 BSBS38_00472 BSBS38_00472 BSBS38_00472 457724 458446 + Kinase A inhibitor Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction%2C but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is noncompetitive with respect to ATP gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00472 BSBS38_00473 BSBS38_00473 BSBS38_00473 458449 459456 + KipI antagonist Counteracts the inhibitory action of KipI on sporulation. May bind to KipI%2C preventing its function as an inhibitor of kinase A gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00473 BSBS38_00474 BSBS38_00474 BSBS38_00474 459469 460224 + HTH-type transcriptional regulator KipR Transcriptional repressor of the kip gene-containing operon%3B Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00474 BSBS38_00475 BSBS38_00475 BSBS38_00475 460288 460929 + Spore germination lipase LipC Lipase involved in spore germination%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00475 BSBS38_00476 BSBS38_00476 BSBS38_00476 461101 461346 + uncharacterized protein gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00476 BSBS38_00477 BSBS38_00477 BSBS38_00477 461352 461639 - uncharacterized protein Contains 1 ABM domain gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00477 BSBS38_00478 BSBS38_00478 BSBS38_00478 461790 463796 + Penicillin-binding protein Belongs to the transpeptidase family gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00478 BSBS38_00479 BSBS38_00479 BSBS38_00479 463897 464799 + putative oxidoreductase YcsN Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: ecc:c2039 null%3B Oxidoreductases gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00479 BSBS38_00480 BSBS38_00480 BSBS38_00480 464985 467069 + Transcriptional regulator MtlR Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00480 BSBS38_00481 BSBS38_00481 acsL acsL 467281 468792 + Long-chain-fatty-acid--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bca:BCE_3436 long-chain acyl-CoA synthetase gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00481 BSBS38_00482 BSBS38_00482 vte3 vte3 468812 469408 - 2-methyl-6-phytyl-1%2C4-hydroquinone methyltransferase Belongs to the methyltransferase superfamily%3B KEGG: ath:AT3G63410 MPBQ/MSBQ methyltransferase gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00482 BSBS38_00483 BSBS38_00483 BSBS38_00483 469563 470423 + General stress protein 39 Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02817 null%3B Oxidoreductases gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00483 BSBS38_00484 BSBS38_00484 BSBS38_00484 470439 470882 + putative D-lyxose ketol-isomerase Belongs to the D-lyxose ketol-isomerase family gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00484 BSBS38_00485 BSBS38_00485 rimL rimL 471029 471580 + Putative ribosomal N-acetyltransferase YdaF Putative N-acetyltransferase. May act on ribosomal proteins (Potential)%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU04210 ribosomal-protein-serine acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00485 BSBS38_00486 BSBS38_00486 BSBS38_00486 471658 472080 + General stress protein gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00486 BSBS38_00487 BSBS38_00487 BSBS38_00487 472586 473395 + uncharacterized protein gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00487 BSBS38_00488 BSBS38_00488 BSBS38_00488 473440 473730 - putative membrane protein YdzA gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00488 BSBS38_00489 BSBS38_00489 BSBS38_00489 473915 474349 + HTH-type transcriptional regulator LrpC Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition. Contains 1 HTH asnC-type DNA-binding domain gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00489 BSBS38_00490 BSBS38_00490 topB topB 474414 476597 + DNA topoisomerase Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bpe:BP0460 DNA topoisomerase III gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00490 BSBS38_00491 BSBS38_00491 BSBS38_00491 476801 477889 + Putative lipoprotein YdaJ gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00491 BSBS38_00492 BSBS38_00492 BSBS38_00492 477870 478418 + putative membrane protein YdaK Contains 1 GGDEF domain gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00492 BSBS38_00493 BSBS38_00493 BSBS38_00493 478521 478721 + putative membrane protein YdaK Contains 1 GGDEF domain gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00493 BSBS38_00494 BSBS38_00494 BSBS38_00494 478711 480438 + uncharacterized protein gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00494 BSBS38_00495 BSBS38_00495 mgdA mgdA 480431 481693 + 1%2C2-diacylglycerol 3-glucosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: synp:Syn7502_03368 1%2C2-diacylglycerol 3-beta-glucosyltransferase gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00495 BSBS38_00496 BSBS38_00496 BSBS38_00496 481690 483810 + uncharacterized protein gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00496 BSBS38_00497 BSBS38_00497 BSBS38_00497 484282 486105 + putative amino acid permease YdaO Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00497 BSBS38_00498 BSBS38_00498 mutT mutT 486164 486613 + 8-oxo-dGTP diphosphatase May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8- oxoguanine%2C 8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo- dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions. MutT specifically degrades 8-oxo-dGTP to the monophosphate (By similarity). Functions%2C in conjuction with ytkD%2C to protect vegetatively growing cells from DNA-damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide). The 2 proteins do not however protect spores%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: dra:DR_0329 8-oxo-dGTP diphosphatase gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00498 BSBS38_00499 BSBS38_00499 poxL poxL 486680 488404 + Pyruvate oxidase Belongs to the TPP enzyme family%3B KEGG: bsu:BSU04340 pyruvate oxidase gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00499 BSBS38_00500 BSBS38_00500 BSBS38_00500 489048 489641 + hypothetical protein gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00500 BSBS38_00501 BSBS38_00501 BSBS38_00501 489638 490612 + hypothetical protein gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00501 BSBS38_00502 BSBS38_00502 BSBS38_00502 490689 490904 + hypothetical protein gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00502 BSBS38_00503 BSBS38_00503 BSBS38_00503 491028 491294 - putative membrane protein YdzK gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00503 BSBS38_00504 BSBS38_00504 BSBS38_00504 491397 492674 - Divalent metal cation transporter MntH H(+)-stimulated%2C divalent metal cation uptake system. Involved in manganese uptake. Can probably also transport cadmium%2C cobalt%2C copper and zinc%2C but not iron. May be the predominant transporter of manganese during logarithmic phase growth%3B Belongs to the NRAMP family gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00504 BSBS38_00505 BSBS38_00505 BSBS38_00505 492904 493161 - UPF0410 protein YdaS Belongs to the UPF0410 family gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00505 BSBS38_00506 BSBS38_00506 BSBS38_00506 493239 493691 - uncharacterized protein gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00506 BSBS38_00507 BSBS38_00507 BSBS38_00507 493809 494627 + uncharacterized protein gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00507 BSBS38_00508 BSBS38_00508 BSBS38_00508 494756 495127 + Glucose starvation-inducible protein gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00508 BSBS38_00509 BSBS38_00509 BSBS38_00509 495258 495599 + uncharacterized protein Belongs to the SchB/CurC family%3B overlaps another CDS with the same product name gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00509 BSBS38_00510 BSBS38_00510 BSBS38_00510 495593 495952 + uncharacterized protein overlaps another CDS with the same product name gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00510 BSBS38_00511 BSBS38_00511 BSBS38_00511 496068 496802 - putative manganese catalase Belongs to the manganese catalase family gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00511 BSBS38_00512 BSBS38_00512 BSBS38_00512 496888 497940 - C4-dicarboxylate-binding protein DctB Part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. Responsible for growth on fumarate and succinate but not malate. Is not directly involved in C4-dicarboxylate uptake%2C but plays a sensory role in the DctS/DctR two-component system which regulates the expression of the dctA C4-dicarboxylate transporter%3B Belongs to the bacterial solute-binding protein 7 family gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00512 BSBS38_00513 BSBS38_00513 dctS dctS 498010 499617 + Histidine kinase Member of the two-component regulatory system DctS/DctR. Probably activates DctR by phosphorylation (By similarity). Essential for expression of dctP%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU04450 two-component system%2C CitB family%2C sensor histidine kinase DctS gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00513 BSBS38_00514 BSBS38_00514 BSBS38_00514 499607 500287 + putative C4-dicarboxylate response regulator DctR Member of the two-component regulatory system DctS/DctR. Essential for expression of dctP%3B Contains 1 response regulatory domain gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00514 BSBS38_00515 BSBS38_00515 BSBS38_00515 500408 501673 + C4-dicarboxylate transport protein Responsible for the transport of succinate and fumarate%2C but not malate%2C across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00515 BSBS38_00516 BSBS38_00516 BSBS38_00516 501801 503153 + hypothetical protein gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00516 BSBS38_00517 BSBS38_00517 BSBS38_00517 503398 503808 + UPF0118 membrane protein YdbI Belongs to the UPF0118 (PerM) family%3B overlaps another CDS with the same product name gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00517 BSBS38_00518 BSBS38_00518 BSBS38_00518 503808 504449 + UPF0118 membrane protein YdbI Belongs to the UPF0118 (PerM) family%3B overlaps another CDS with the same product name gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00518 BSBS38_00519 BSBS38_00519 BSBS38_00519 504572 504736 + hypothetical protein gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00519 BSBS38_00520 BSBS38_00520 BSBS38_00520 504729 505655 + putative ABC transporter ATP-binding protein YdbJ Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00520 BSBS38_00521 BSBS38_00521 BSBS38_00521 505648 506415 + putative membrane protein YdbK gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00521 BSBS38_00522 BSBS38_00522 BSBS38_00522 506510 506845 + uncharacterized protein gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00522 BSBS38_00523 BSBS38_00523 BSBS38_00523 506973 508118 + Short-chain acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: pah:Poras_0582 butyryl-CoA dehydrogenase gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00523 BSBS38_00524 BSBS38_00524 BSBS38_00524 508142 508288 - uncharacterized protein gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00524 BSBS38_00525 BSBS38_00525 BSBS38_00525 508275 508439 - hypothetical protein gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00525 BSBS38_00526 BSBS38_00526 BSBS38_00526 508687 509559 + putative transporter YdbO Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00526 BSBS38_00527 BSBS38_00527 BSBS38_00527 509574 509894 - Thioredoxin-like protein YdbP Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00527 BSBS38_00528 BSBS38_00528 BSBS38_00528 510047 511132 + D-alanine--D-alanine ligase Cell wall formation%3B Belongs to the D-alanine--D-alanine ligase family%3B Contains 1 ATP-grasp domain%3B KEGG: bsr:I33_0522 D-alanine-D-alanine ligase gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00528 BSBS38_00529 BSBS38_00529 murF murF 511132 512577 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide%2C the precursor of murein%3B Belongs to the MurCDEF family. MurF subfamily%3B KEGG: bsut:BSUB_00500 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00529 BSBS38_00530 BSBS38_00530 deaD deaD 512977 514461 + RNA helicase DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions%2C has RNA- dependent ATPase activity%3B Belongs to the DEAD box helicase family. CshA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU04580 ATP-dependent RNA helicase DeaD gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00530 BSBS38_00531 BSBS38_00531 BSBS38_00531 514634 515113 + UPF0699 transmembrane protein YdbS Belongs to the UPF0699 family gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00531 BSBS38_00532 BSBS38_00532 BSBS38_00532 515103 516584 + UPF0699 transmembrane protein YdbT Belongs to the UPF0699 family gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00532 BSBS38_00533 BSBS38_00533 gluP gluP 516581 517180 - Rhomboid protease Belongs to the peptidase S54 family%3B KEGG: tap:GZ22_09190 rhomboid protease GluP gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00533 BSBS38_00534 BSBS38_00534 acpS acpS 517275 517640 + Holo-[acyl-carrier-protein] synthase Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein%3B Belongs to the P-Pant transferase superfamily. AcpS family%3B KEGG: bsu:BSU04620 holo-(acyl-carrier protein) synthase gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00534 BSBS38_00535 BSBS38_00535 BSBS38_00535 517701 518822 + Sporulation protein YdcC required for efficient sporulation gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00535 BSBS38_00536 BSBS38_00536 BSBS38_00536 518937 519707 + Alanine racemase Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bsu:BSU04640 alanine racemase gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00536 BSBS38_00537 BSBS38_00537 BSBS38_00537 519776 520105 + Alanine racemase Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: mme:Marme_0084 alanine racemase gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00537 BSBS38_00538 BSBS38_00538 BSBS38_00538 520221 520502 + Antitoxin EndoAI Antitoxin component of a type II toxin-antitoxin (TA) module. Antitoxin that directly inhibits activity of EndoA in vitro. Upon expression in E. coli counteracts inhibitory effect of endoribonuclease EndoA. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the MazE/EndoAI family gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00538 BSBS38_00539 BSBS38_00539 mazF mazF 520507 520857 + Endoribonuclease EndoA Toxic component of a type II toxin-antitoxin (TA) module. Specific for 5'-UACAU-3' sequences%2C cleaving after the first U (PubMed:21763692). Yields cleavage products with 3' phosphate and 5' hydroxyl groups (PubMed:15882409). Cannot digest substrate with a UUdUACAUAA cleavage site (PubMed:24120662). Overexpression is toxic for cell growth (shown in E. coli)%2C probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antitoxin EndoAI. Toxin activity cannot be inhibited by MazE from E. coli. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the PemK/MazF family%3B KEGG: geo:Geob_2001 mRNA interferase MazF%3B Acting on ester bonds gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00539 BSBS38_00540 BSBS38_00540 BSBS38_00540 520976 521797 + RsbT co-antagonist protein RsbRA Acts as a positive regulator of sigma-B activity in response to salt and heat stress by stimulating the activity of the RsbT kinase toward RsbS in vitro. One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00540 BSBS38_00541 BSBS38_00541 BSBS38_00541 521802 522167 + RsbT antagonist protein RsbS Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU%3B Contains 1 STAS domain gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00541 BSBS38_00542 BSBS38_00542 rsbT rsbT 522171 522572 + Non-specific serine/threonine protein kinase Provides the crucial link between the upstream module (communication of environmental stress) and the downstream module (integration of the environmental signals with signals of energy stress) that compose the signal transduction pathway controlling the sigma-B factor. Phosphorylates and inactivates its specific antagonist protein RsbS thanks to its serine kinase activity. Upon phosphorylation of RsbS%2C RsbT is released to stimulate RsbU%2C a PP2C phosphatase%2C thereby initiating the signaling cascade that ultimately activates sigma-B. The activity of the RsbU phosphatase may be stimulated by a long-lived interaction with RsbT and the serine kinase function of RsbT is not required to directly modify RsbU. Also phosphorylates RsbR thanks to its threonine kinase activity%2C preventing it to phosphorylate RsbT%3B KEGG: bsu:BSU04690 serine/threonine-protein kinase RsbT gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00542 BSBS38_00543 BSBS38_00543 BSBS38_00543 522584 523591 + Phosphoserine phosphatase RsbU Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to environmental stress conveyed from the RsbXST module%3B Contains 1 PPM-type phosphatase domain gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00543 BSBS38_00544 BSBS38_00544 BSBS38_00544 523653 523982 + Anti-sigma-B factor antagonist Positive regulator of sigma-B activity. Non- phosphorylated RsbV binds to RsbW%2C preventing its association with sigma-B. When phosphorylated%2C releases RsbW%2C which is then free to complex with and inactivate sigma-B%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00544 BSBS38_00545 BSBS38_00545 rsbW rsbW 523979 524461 + Non-specific serine/threonine protein kinase Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein%2C RsbV. Upon phosphorylation of RsbV%2C RsbW is released and binds to sigma-B%2C thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)%3B Belongs to the anti-sigma-factor family%3B KEGG: bsu:BSU04720 serine/threonine-protein kinase RsbW gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00545 BSBS38_00546 BSBS38_00546 BSBS38_00546 524427 525215 + RNA polymerase sigma-B factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma B is not essential for sporulatio%3B rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation. May play a role in the ability of the bacterium to adapt to various stresses but is not essential for its survival under these conditions. Positively regulates expression of its own operon. Belongs to the sigma-70 factor family. SigB subfamily gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00546 BSBS38_00547 BSBS38_00547 rsbX rsbX 525215 525814 + Phosphoserine phosphatase Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU04740 negative regulator of sigma-B (phosphoserine phosphatase) gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00547 BSBS38_00548 BSBS38_00548 BSBS38_00548 525924 526106 + hypothetical protein gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00548 BSBS38_00549 BSBS38_00549 BSBS38_00549 526188 526349 + uncharacterized protein gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00549 BSBS38_00550 BSBS38_00550 BSBS38_00550 526346 526786 + UPF0310 protein YdcG Belongs to the UPF0310 family gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00550 BSBS38_00551 BSBS38_00551 BSBS38_00551 526770 527213 + putative HTH-type transcriptional regulator YdcH Contains 1 HTH marR-type DNA-binding domain gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00551 BSBS38_00552 BSBS38_00552 BSBS38_00552 527307 529466 + uncharacterized protein Contains 1 S1 motif domain gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00552 BSBS38_00553 BSBS38_00553 BSBS38_00553 529693 530145 + Protein SprT-like protein Belongs to the SprT family%3B Contains 1 SprT-like domain gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00553 BSBS38_00554 BSBS38_00554 BSBS38_00554 530268 530342 + tRNA-Asn tRNA gene553 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00554 BSBS38_00555 BSBS38_00555 BSBS38_00555 530347 530437 + tRNA-Ser tRNA gene554 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00555 BSBS38_00556 BSBS38_00556 BSBS38_00556 530467 530538 + tRNA-Glu tRNA gene555 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00556 BSBS38_00557 BSBS38_00557 BSBS38_00557 530550 530624 + tRNA-Gln tRNA gene556 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00557 BSBS38_00558 BSBS38_00558 BSBS38_00558 530653 530728 + tRNA-Lys tRNA gene557 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00558 BSBS38_00559 BSBS38_00559 BSBS38_00559 530740 530821 + tRNA-Leu tRNA gene558 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00559 BSBS38_00560 BSBS38_00560 BSBS38_00560 530908 530994 + tRNA-Leu tRNA gene559 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00560 BSBS38_00561 BSBS38_00561 BSBS38_00561 531076 532185 - ICEBs1 integrase Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome%2C attB%2C and a site in the circular form of ICEBs1%2C attICEBs1%3B Belongs to the 'phage' integrase family gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00561 BSBS38_00562 BSBS38_00562 lexA lexA 532710 533087 - Repressor LexA Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: ddh:Desde_3216 repressor LexA gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00562 BSBS38_00563 BSBS38_00563 BSBS38_00563 533361 533552 + ICEBs1 excisionase Required for the excision of the integrative and conjugative element ICEBs1. Excision of ICEBs1 requires two sites%2C attL and attR%2C at the left and right ends of the integrated ICEBs1 gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00563 BSBS38_00564 BSBS38_00564 BSBS38_00564 533549 533809 + uncharacterized protein gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00564 BSBS38_00565 BSBS38_00565 BSBS38_00565 533863 534123 + uncharacterized protein gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00565 BSBS38_00566 BSBS38_00566 BSBS38_00566 534493 534867 + Putative uncharacterized protein YdcP gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00566 BSBS38_00567 BSBS38_00567 BSBS38_00567 534925 535110 + hypothetical protein gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00567 BSBS38_00568 BSBS38_00568 BSBS38_00568 535049 536545 + Ftsk domain-containing protein YdcQ Contains 1 FtsK domain gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00568 BSBS38_00569 BSBS38_00569 BSBS38_00569 536538 537596 + Putative DNA relaxase NicK Probable DNA relaxase involved in the transfer of the integrative and conjugative element ICEBs1. Required for the transfer of ICEBs1. Probably mediates conjugation of ICEBs1 by nicking at oriT on the conjugative element and facilitates the translocation of a single strand of ICEBs1 DNA through a transmembrane conjugation pore into the recipient cell%3B Belongs to the plasmid replication initiation factor family gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00569 BSBS38_00570 BSBS38_00570 BSBS38_00570 537868 538143 + hypothetical protein gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00570 BSBS38_00571 BSBS38_00571 BSBS38_00571 538157 538423 + uncharacterized protein gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00571 BSBS38_00572 BSBS38_00572 BSBS38_00572 538530 538748 + uncharacterized protein overlaps another CDS with the same product name gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00572 BSBS38_00573 BSBS38_00573 BSBS38_00573 538738 539802 + uncharacterized protein overlaps another CDS with the same product name gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00573 BSBS38_00574 BSBS38_00574 BSBS38_00574 539814 540062 + uncharacterized protein gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00574 BSBS38_00575 BSBS38_00575 BSBS38_00575 540075 540599 + uncharacterized protein overlaps another CDS with the same product name gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00575 BSBS38_00576 BSBS38_00576 BSBS38_00576 540589 542982 + uncharacterized protein overlaps another CDS with the same product name gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00576 BSBS38_00577 BSBS38_00577 BSBS38_00577 543000 543326 + uncharacterized protein gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00577 BSBS38_00578 BSBS38_00578 BSBS38_00578 543339 545765 + putative membrane protein YddG gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00578 BSBS38_00579 BSBS38_00579 mepH mepH 545762 546559 + putative endopeptidase YddH Belongs to the peptidase C40 family%3B KEGG: eco:b1655 murein DD-endopeptidase%3B Acting on peptide bonds (peptidases) gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00579 BSBS38_00580 BSBS38_00580 BSBS38_00580 546765 547271 + uncharacterized protein gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00580 BSBS38_00581 BSBS38_00581 BSBS38_00581 547334 547720 + uncharacterized protein gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00581 BSBS38_00582 BSBS38_00582 rapI rapI 547953 549083 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU05010 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00582 BSBS38_00583 BSBS38_00583 BSBS38_00583 549070 549186 + hypothetical protein gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00583 BSBS38_00584 BSBS38_00584 BSBS38_00584 549242 550333 - DNA (cytosine-5-)-methyltransferase This methylase recognizes the double-stranded sequence GCSGC%2C causes specific methylation on C-? on both strands%2C and protects the DNA from cleavage by the NgoFVII endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bce:BC0941 DNA (cytosine-5)-methyltransferase 1 gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00584 BSBS38_00585 BSBS38_00585 BSBS38_00585 550388 551725 - Type-2 restriction enzyme BsuMI component YdjA gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00585 BSBS38_00586 BSBS38_00586 mcrB mcrB 551722 553452 - Type-2 restriction enzyme BsuMI component YdiS KEGG: eclx:LI66_02825 5-methylcytosine-specific restriction enzyme B%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00586 BSBS38_00587 BSBS38_00587 BSBS38_00587 553691 554344 + putative HTH-type transcriptional regulator YdhC Contains 1 HTH gntR-type DNA-binding domain gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00587 BSBS38_00588 BSBS38_00588 BSBS38_00588 554636 555154 - hypothetical protein gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00588 BSBS38_00589 BSBS38_00589 BSBS38_00589 555165 556157 - Ribonuclease YobL Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-600) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YobK%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00589 BSBS38_00590 BSBS38_00590 BSBS38_00590 556473 558020 + Transposase for insertion sequence element IS21-like protein Involved in the transposition of the insertion sequence%3B Belongs to the transposase IS21/IS408/IS1162 family%3B Contains 1 HTH IS21-type DNA-binding domain%3B Contains 1 integrase catalytic domain gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00590 BSBS38_00591 BSBS38_00591 BSBS38_00591 558017 558775 + Insertion sequence IS21 putative ATP-binding protein One of two proteins expressed only when there is a tandem repeat of the IS21 insertion sequence%2C it is necessary for the transposition of plasmids with that tandem repeat. Belongs to the IS21/IS1162 putative ATP-binding protein family gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00591 BSBS38_00592 BSBS38_00592 BSBS38_00592 558815 559372 - Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00592 BSBS38_00593 BSBS38_00593 BSBS38_00593 559832 560086 + putative HTH-type transcriptional regulator Contains 1 HTH cro/C1-type DNA-binding domain gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00593 BSBS38_00594 BSBS38_00594 BSBS38_00594 560083 560436 + hypothetical protein gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00594 BSBS38_00595 BSBS38_00595 BSBS38_00595 561257 561433 + putative membrane protein YdzM/YouB gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00595 BSBS38_00596 BSBS38_00596 BSBS38_00596 561458 562144 + uncharacterized protein gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00596 BSBS38_00597 BSBS38_00597 BSBS38_00597 562569 562754 + putative membrane protein YdzN gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00597 BSBS38_00598 BSBS38_00598 BSBS38_00598 563104 563697 + putative protease YdeA Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00598 BSBS38_00599 BSBS38_00599 BSBS38_00599 563960 564160 + Cold shock protein Contains 1 CSD (cold-shock) domain gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00599 BSBS38_00600 BSBS38_00600 BSBS38_00600 564826 566064 - Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00600 BSBS38_00601 BSBS38_00601 BSBS38_00601 566220 566681 - Putative transcription factor YdeB Belongs to the CarD family gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00601 BSBS38_00602 BSBS38_00602 BSBS38_00602 567250 568134 - Putative permease-like protein YdzE Belongs to the EamA transporter family%3B Contains 1 EamA domain gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00602 BSBS38_00603 BSBS38_00603 BSBS38_00603 568365 569240 - putative HTH-type transcriptional regulator YdeC Contains 1 HTH araC/xylS-type DNA-binding domain gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00603 BSBS38_00604 BSBS38_00604 BSBS38_00604 569353 570312 + putative transporter YdeD Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00604 BSBS38_00605 BSBS38_00605 BSBS38_00605 570453 571337 - putative HTH-type transcriptional regulator YdeE Contains 1 HTH araC/xylS-type DNA-binding domain gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00605 BSBS38_00606 BSBS38_00606 BSBS38_00606 571564 572952 + putative HTH-type transcriptional regulator YdeF In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00606 BSBS38_00607 BSBS38_00607 BSBS38_00607 573063 573302 + putative MFS-type transporter YdeG Belongs to the major facilitator superfamily%3B overlaps another CDS with the same product name gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00607 BSBS38_00608 BSBS38_00608 BSBS38_00608 573251 574354 + putative MFS-type transporter YdeG Belongs to the major facilitator superfamily%3B overlaps another CDS with the same product name gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00608 BSBS38_00609 BSBS38_00609 BSBS38_00609 574585 574959 + putative membrane protein YdeH gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00609 BSBS38_00610 BSBS38_00610 BSBS38_00610 575195 575788 + uncharacterized protein gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00610 BSBS38_00611 BSBS38_00611 BSBS38_00611 576133 576792 - putative lipoprotein YdeJ gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00611 BSBS38_00612 BSBS38_00612 BSBS38_00612 576983 577339 + hypothetical protein gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00612 BSBS38_00613 BSBS38_00613 BSBS38_00613 577577 577852 - hypothetical protein gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00613 BSBS38_00614 BSBS38_00614 BSBS38_00614 578185 578730 + putative HTH-type transcriptional regulator YxbF Contains 2 HTH tetR-type DNA-binding domains gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00614 BSBS38_00615 BSBS38_00615 BSBS38_00615 579338 579736 - putative transporter YdeK Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00615 BSBS38_00616 BSBS38_00616 BSBS38_00616 579891 581282 + putative HTH-type transcriptional regulator YdeL In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00616 BSBS38_00617 BSBS38_00617 BSBS38_00617 581476 581901 + uncharacterized protein Contains 1 MaoC-like domain gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00617 BSBS38_00618 BSBS38_00618 BSBS38_00618 581954 582526 - Putative hydrolase Belongs to the RBBP9 family gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00618 BSBS38_00619 BSBS38_00619 BSBS38_00619 582608 582937 - putative HTH-type transcriptional regulator YdzF Contains 1 HTH hxlR-type DNA-binding domain gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00619 BSBS38_00620 BSBS38_00620 BSBS38_00620 583190 584062 + UPF0750 membrane protein YdeO Belongs to the UPF0750 family gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00620 BSBS38_00621 BSBS38_00621 BSBS38_00621 584636 584971 + HTH-type transcriptional repressor AseR Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to its promoter. Binding of arsenite or antimonite causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00621 BSBS38_00622 BSBS38_00622 BSBS38_00622 584984 586291 + Putative arsenical pump membrane protein YdfA Belongs to the ArsB family gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00622 BSBS38_00623 BSBS38_00623 BSBS38_00623 586792 587568 + putative N-acetyltransferase YdfB Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: btk:BT9727_4354 null%3B Transferring groups other than amino-acyl groups gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00623 BSBS38_00624 BSBS38_00624 BSBS38_00624 587625 588545 - putative transporter YdfC Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00624 BSBS38_00625 BSBS38_00625 BSBS38_00625 588678 589928 + putative HTH-type transcriptional regulator YdfD In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00625 BSBS38_00626 BSBS38_00626 BSBS38_00626 590193 591635 - Cysteine sulfinic acid decarboxylase Belongs to the group II decarboxylase family gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00626 BSBS38_00627 BSBS38_00627 BSBS38_00627 591756 592379 - uncharacterized protein Belongs to the flavoredoxin family gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00627 BSBS38_00628 BSBS38_00628 BSBS38_00628 592469 593149 + putative HTH-type transcriptional regulator YdfF Contains 1 HTH arsR-type DNA-binding domain gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00628 BSBS38_00629 BSBS38_00629 BSBS38_00629 593229 593672 - uncharacterized protein gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00629 BSBS38_00630 BSBS38_00630 BSBS38_00630 593758 593931 - putative membrane protein YdzP gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00630 BSBS38_00631 BSBS38_00631 ydfH ydfH 594405 594524 + Histidine kinase Member of the two-component regulatory system YdfH/YdfI. May activate YdfI by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU05410 two-component system%2C NarL family%2C sensor histidine kinase YdfH%3B overlaps another CDS with the same product name gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00631 BSBS38_00632 BSBS38_00632 BSBS38_00632 594500 595567 + Histidine kinase Member of the two-component regulatory system YdfH/YdfI. May activate YdfI by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU05410 two-component system%2C NarL family%2C sensor histidine kinase YdfH%3B overlaps another CDS with the same product name gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00632 BSBS38_00633 BSBS38_00633 BSBS38_00633 595560 596201 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00633 BSBS38_00634 BSBS38_00634 BSBS38_00634 596317 598491 + Membrane protein YdfJ Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00634 BSBS38_00635 BSBS38_00635 BSBS38_00635 598576 598671 + hypothetical protein gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00635 BSBS38_00636 BSBS38_00636 pcaD pcaD 598903 599805 - 3-oxoadipate enol-lactonase Belongs to the AB hydrolase superfamily%3B KEGG: afo:Afer_1307 3-oxoadipate enol-lactonase gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00636 BSBS38_00637 BSBS38_00637 BSBS38_00637 600007 600696 - putative membrane protein YdfK gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00637 BSBS38_00638 BSBS38_00638 BSBS38_00638 600786 601598 - putative HTH-type transcriptional regulator YdfL Contains 1 HTH merR-type DNA-binding domain gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00638 BSBS38_00639 BSBS38_00639 BSBS38_00639 601712 602605 - putative transporter YdfM Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00639 BSBS38_00640 BSBS38_00640 BSBS38_00640 603083 603703 + Putative NAD(P)H nitroreductase MhqN Putative nitroreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the nitroreductase family%3B KEGG: bsr:I33_0620 putative NAD(P)H nitroreductase%3B Oxidoreductases gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00640 BSBS38_00641 BSBS38_00641 BSBS38_00641 603719 604657 + Putative ring-cleaving dioxygenase MhqO Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00641 BSBS38_00642 BSBS38_00642 BSBS38_00642 604756 605145 + Putative oxidoreductase MhqP Putative oxidoreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the DoxX family gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00642 BSBS38_00643 BSBS38_00643 BSBS38_00643 605331 605669 + Thioredoxin-like protein YdfQ Contains 1 thioredoxin domain gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00643 BSBS38_00644 BSBS38_00644 BSBS38_00644 605709 605945 - uncharacterized protein gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00644 BSBS38_00645 BSBS38_00645 BSBS38_00645 606150 606443 - hypothetical protein gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00645 BSBS38_00646 BSBS38_00646 BSBS38_00646 606477 606707 - Spore germination protein-like protein YdzR Belongs to the GerPA/GerPF family gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00646 BSBS38_00647 BSBS38_00647 BSBS38_00647 606831 607508 - UPF0702 transmembrane protein YdfR Belongs to the UPF0702 family gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00647 BSBS38_00648 BSBS38_00648 BSBS38_00648 607620 608327 + UPF0702 transmembrane protein YdfS Belongs to the UPF0702 family gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00648 BSBS38_00649 BSBS38_00649 BSBS38_00649 608342 608773 - Spore coat protein Belongs to the small heat shock protein (HSP20) family gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00649 BSBS38_00650 BSBS38_00650 BSBS38_00650 608786 609028 - uncharacterized protein gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00650 BSBS38_00651 BSBS38_00651 BSBS38_00651 609042 609314 - uncharacterized protein gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00651 BSBS38_00652 BSBS38_00652 BSBS38_00652 609614 610213 + putative HTH-type transcriptional regulator YdgC Contains 1 HTH tetR-type DNA-binding domain gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00652 BSBS38_00653 BSBS38_00653 BSBS38_00653 610210 610554 + uncharacterized protein gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00653 BSBS38_00654 BSBS38_00654 rimI rimI 610717 611190 + Ribosomal-protein-alanine N-acetyltransferase Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: cst:CLOST_2300 ribosomal-protein-alanine N-acetyltransferase gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00654 BSBS38_00655 BSBS38_00655 BSBS38_00655 611351 612997 - Nucleotide-binding protein ExpZ Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00655 BSBS38_00656 BSBS38_00656 BSBS38_00656 613317 614693 - putative transporter YdgF Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00656 BSBS38_00657 BSBS38_00657 BSBS38_00657 614865 615383 - Protein DinB Belongs to the DinB family gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00657 BSBS38_00658 BSBS38_00658 BSBS38_00658 615498 616010 + putative HTH-type transcriptional regulator YdgG Contains 1 HTH marR-type DNA-binding domain gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00658 BSBS38_00659 BSBS38_00659 BSBS38_00659 616007 618664 + Putative membrane protein YdgH Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00659 BSBS38_00660 BSBS38_00660 BSBS38_00660 618811 619440 - Putative NAD(P)H nitroreductase YdgI Belongs to the nitroreductase family%3B KEGG: ban:BA_3040 null%3B Oxidoreductases gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00660 BSBS38_00661 BSBS38_00661 BSBS38_00661 619456 619890 - putative HTH-type transcriptional regulator YdgJ Contains 1 HTH marR-type DNA-binding domain gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00661 BSBS38_00662 BSBS38_00662 BSBS38_00662 620262 621125 + putative MFS-type transporter YdgK Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00662 BSBS38_00663 BSBS38_00663 BSBS38_00663 621140 621469 + putative MFS-type transporter YdgK Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00663 BSBS38_00664 BSBS38_00664 BSBS38_00664 621506 622243 - UPF0721 transmembrane protein YdhB Belongs to the UPF0721 family gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00664 BSBS38_00665 BSBS38_00665 BSBS38_00665 622491 623165 + putative HTH-type transcriptional regulator YdhC Contains 1 HTH gntR-type DNA-binding domain gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00665 BSBS38_00666 BSBS38_00666 BSBS38_00666 623292 624080 + Putative sporulation-specific glycosylase YdhD Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 2 LysM repeats gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00666 BSBS38_00667 BSBS38_00667 BSBS38_00667 624098 624553 + Putative sporulation-specific glycosylase YdhD Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 2 LysM repeats gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00667 BSBS38_00668 BSBS38_00668 BSBS38_00668 624715 625902 + putative UDP-glucosyltransferase YdhE Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00668 BSBS38_00669 BSBS38_00669 BSBS38_00669 625941 626651 - uncharacterized protein gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00669 BSBS38_00670 BSBS38_00670 BSBS38_00670 626717 628105 - Alkaline phosphatase Belongs to the alkaline phosphatase family%3B KEGG: bsu:BSU05740 alkaline phosphatase gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00670 BSBS38_00671 BSBS38_00671 BSBS38_00671 628401 628550 + Intracellular iron chaperone frataxin Possible global iron distributor for the cell. Promotes the biosynthesis of iron-sulfur clusters by delivering Fe to the iron-sulfur cluster assembly scaffold protein SufU. In the presence of SufS and L-cysteine reconstitutes Fe-S clusters on SufU%2C which when further incubated with apo-aconitase (citB) reconstitutes aconitase activity. Able to reconstitute an Fe-S cluster on Thermotoga maritima IscU%3B overlaps another CDS with the same product name gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00671 BSBS38_00672 BSBS38_00672 BSBS38_00672 628511 628807 + Intracellular iron chaperone frataxin Possible global iron distributor for the cell. Promotes the biosynthesis of iron-sulfur clusters by delivering Fe to the iron-sulfur cluster assembly scaffold protein SufU. In the presence of SufS and L-cysteine reconstitutes Fe-S clusters on SufU%2C which when further incubated with apo-aconitase (citB) reconstitutes aconitase activity. Able to reconstitute an Fe-S cluster on Thermotoga maritima IscU%3B overlaps another CDS with the same product name gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00672 BSBS38_00673 BSBS38_00673 BSBS38_00673 628882 629379 - uncharacterized protein gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00673 BSBS38_00674 BSBS38_00674 BSBS38_00674 629397 629876 - DNA-3-methyladenine glycosylase I Contains 1 N-acetyltransferase domain%3B KEGG: bha:BH1453 DNA-3-methyladenine glycosylase I gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00674 BSBS38_00675 BSBS38_00675 BSBS38_00675 629947 630924 + uncharacterized protein Contains 1 HD domain gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00675 BSBS38_00676 BSBS38_00676 BSBS38_00676 631117 631686 + uncharacterized protein gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00676 BSBS38_00677 BSBS38_00677 BSBS38_00677 631699 632865 - Purine efflux pump PbuE Involved in the efflux of purine ribonucleosides%2C such as guanosine%2C adenosine and inosine%2C as well as purine bases guanine%2C adenine and hypoxanthine%2C and purine base analogs 2%2C6- diaminopurine and 6-mercaptopurine. Therefore plays a role in maintaining the cellular purine base pools and protecting cells against toxic purine base analogs. Modulates expression of the purR and G-box regulons (By similarity)%3B Belongs to the major facilitator superfamily. DHA1 family. PbuE (TC 2. A. 1. 2. 25) subfamily gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00677 BSBS38_00678 BSBS38_00678 celA celA 633198 633509 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIB type-3 domain%3B KEGG: eca:ECA3645 PTS system%2C cellobiose-specific IIB component%3B overlaps another CDS with the same product name gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00678 BSBS38_00679 BSBS38_00679 celC celC 633509 633724 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIA type-3 domain%3B KEGG: bsu:BSU05820 PTS system%2C cellobiose-specific IIA component%3B overlaps another CDS with the same product name gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00679 BSBS38_00680 BSBS38_00680 BSBS38_00680 633860 634642 + Oligo-beta-mannoside permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIC type-3 domain%3B overlaps another CDS with the same product name gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00680 BSBS38_00681 BSBS38_00681 BSBS38_00681 634624 635187 + Oligo-beta-mannoside permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIC type-3 domain%3B overlaps another CDS with the same product name gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00681 BSBS38_00682 BSBS38_00682 BSBS38_00682 635205 636602 + 6-phospho-beta-glucosidase Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides%2C although very weakly%2C and plays only a minor role%2C if any%2C in the degradation of these substrates in vivo%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bsl:A7A1_1388 6-phospho-beta-glucosidase gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00682 BSBS38_00683 BSBS38_00683 BSBS38_00683 636751 637464 + HTH-type transcriptional regulator GmuR Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan%3B Contains 1 HTH gntR-type DNA-binding domain gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00683 BSBS38_00684 BSBS38_00684 scrK scrK 637493 638392 + Fructokinase Seems to be involved in the degradation of glucomannan%3B Belongs to the ROK (NagC/XylR) family%3B KEGG: psal:PSLF89_2821 fructokinase gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00684 BSBS38_00685 BSBS38_00685 manA manA 638389 639336 + Mannose-6-phosphate isomerase Seems to be involved in the degradation of glucomannan%3B Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bsu:BSU05870 mannose-6-phosphate isomerase gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00685 BSBS38_00686 BSBS38_00686 gmuG gmuG 639355 640443 + Mannan endo-1%2C4-beta-mannosidase Involved in the degradation of glucomannan. Catalyzes the endo hydrolysis of beta-1%2C4-linked mannan%2C galactomannan and glucomannan%3B Belongs to the glycosyl hydrolase 26 family%3B Contains 1 GH26 (glycosyl hydrolase family 26) domain%3B KEGG: bsu:BSU05880 mannan endo-1%2C4-beta-mannosidase gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00686 BSBS38_00687 BSBS38_00687 BSBS38_00687 640502 641242 - putative manganese catalase Belongs to the manganese catalase family gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00687 BSBS38_00688 BSBS38_00688 BSBS38_00688 641674 641750 + tRNA-Arg tRNA gene687 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00688 BSBS38_00689 BSBS38_00689 BSBS38_00689 641764 641837 + tRNA-Gly tRNA gene688 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00689 BSBS38_00690 BSBS38_00690 BSBS38_00690 641998 643547 + 16S ribosomal RNA rRNA gene689 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00690 BSBS38_00691 BSBS38_00691 BSBS38_00691 643718 646645 + 23S ribosomal RNA rRNA gene690 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00691 BSBS38_00692 BSBS38_00692 BSBS38_00692 646700 646815 + 5S ribosomal RNA rRNA gene691 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00692 BSBS38_00693 BSBS38_00693 BSBS38_00693 646830 646906 + tRNA-Met tRNA gene692 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00693 BSBS38_00694 BSBS38_00694 BSBS38_00694 646955 647031 + tRNA-Asp tRNA gene693 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00694 BSBS38_00695 BSBS38_00695 thiL thiL 647211 648188 + Thiamine-phosphate kinase Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP)%2C the active form of vitamin B1%3B Belongs to the thiamine-monophosphate kinase family%3B KEGG: bsu:BSU05900 thiamine-monophosphate kinase gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00695 BSBS38_00696 BSBS38_00696 BSBS38_00696 648203 648679 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro%2C which is modulated by the oligomeric status of the protein%3B Belongs to the TsaE family gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00696 BSBS38_00697 BSBS38_00697 BSBS38_00697 648660 649349 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaB Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD%3B Belongs to the KAE1 / TsaD family. TsaB subfamily gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00697 BSBS38_00698 BSBS38_00698 BSBS38_00698 649359 649814 + Ribosomal-protein-alanine N-acetyltransferase This enzyme acetylates the N-terminal alanine of ribosomal protein S18%3B Belongs to the acetyltransferase family. RimI subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU05930 ribosomal-protein-alanine N-acetyltransferase gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00698 BSBS38_00699 BSBS38_00699 kae1 kae1 649825 650847 + N(6)-L-threonylcarbamoyladenine synthase Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance (By similarity). May have a role in embryonic development in plants%3B Belongs to the KAE1 / TsaD family%3B KEGG: eco:b3064 N6-L-threonylcarbamoyladenine synthase gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00699 BSBS38_00700 BSBS38_00700 BSBS38_00700 650931 651134 + hypothetical protein gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00700 BSBS38_00701 BSBS38_00701 BSBS38_00701 651073 653001 - Iron-chelate-transporting ATPase Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily%3B Contains 2 ABC transporter domains%3B KEGG: yee:YE5303_30631 iron complex transport system ATP-binding protein gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00701 BSBS38_00702 BSBS38_00702 moaC moaC 653127 653639 + Cyclic pyranopterin phosphate synthase Together with MoaA%2C is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the MoaC family%3B KEGG: bok:DM82_179 cyclic pyranopterin phosphate synthase gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00702 BSBS38_00703 BSBS38_00703 BSBS38_00703 653636 654283 + Redox-sensing transcriptional repressor Rex Modulates transcription in response to changes in cellular NADH/NAD(+) redox state%3B Belongs to the transcriptional regulatory Rex family gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00703 BSBS38_00704 BSBS38_00704 BSBS38_00704 654305 654478 + Sec-independent protein translocase protein TatAy Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for YwbN secretion%3B Belongs to the TatA/E family gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00704 BSBS38_00705 BSBS38_00705 BSBS38_00705 654494 655249 + Sec-independent protein translocase protein TatCy Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for YwbN secretion%3B Belongs to the TatC family gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00705 BSBS38_00706 BSBS38_00706 BSBS38_00706 655481 655672 - putative lipoprotein YdiK gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00706 BSBS38_00707 BSBS38_00707 BSBS38_00707 655669 656403 - Putative membrane peptidase YdiL May function as endopeptidase which proteolytically removes the C-terminal three residues of farnesylated peptides containing the CAAX motif where C is cysteine%2C A is an aliphatic amino acid and X is any amino acid%3B Belongs to the peptidase U48 family gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00707 BSBS38_00708 BSBS38_00708 BSBS38_00708 656642 656926 + 10 kDa chaperonin Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter%3B Belongs to the GroES chaperonin family gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00708 BSBS38_00709 BSBS38_00709 BSBS38_00709 656973 658604 + 60 kDa chaperonin Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions%3B Belongs to the chaperonin (HSP60) family gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00709 BSBS38_00710 BSBS38_00710 BSBS38_00710 658872 659243 - hypothetical protein gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00710 BSBS38_00711 BSBS38_00711 BSBS38_00711 659724 660527 + hypothetical protein gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00711 BSBS38_00712 BSBS38_00712 BSBS38_00712 660528 661472 + hypothetical protein gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00712 BSBS38_00713 BSBS38_00713 BSBS38_00713 661788 664289 - Transcription activator GutR Activator of the glucitol dehydrogenase gene (gutB). Contains 3 TPR repeats gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00713 BSBS38_00714 BSBS38_00714 sorD sorD 664491 665552 + L-iditol 2-dehydrogenase Reduces glucitol to fructose. Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU06150 L-iditol 2-dehydrogenase gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00714 BSBS38_00715 BSBS38_00715 BSBS38_00715 665626 667017 + putative glucitol transport protein GutA Probably involved in glucitol uptake. Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00715 BSBS38_00716 BSBS38_00716 BSBS38_00716 667112 668074 + Fructokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU06170 fructokinase gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00716 BSBS38_00717 BSBS38_00717 BSBS38_00717 668270 668953 + Phage shock protein A like protein Belongs to the PspA/IM30 family gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00717 BSBS38_00718 BSBS38_00718 BSBS38_00718 669019 670044 + uncharacterized protein gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00718 BSBS38_00719 BSBS38_00719 BSBS38_00719 670044 670808 + UPF0603 protein YdjH Belongs to the UPF0603 family gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00719 BSBS38_00720 BSBS38_00720 BSBS38_00720 670839 671810 + uncharacterized protein gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00720 BSBS38_00721 BSBS38_00721 BSBS38_00721 671858 672640 - putative membrane protein YdjJ gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00721 BSBS38_00722 BSBS38_00722 BSBS38_00722 672682 672882 - putative membrane protein YdjJ gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00722 BSBS38_00723 BSBS38_00723 BSBS38_00723 673466 674887 + Major myo-inositol transporter IolT Major myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00723 BSBS38_00724 BSBS38_00724 butB butB 674935 675975 - (R%2CR)-butanediol dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU06240 (R%2CR)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00724 BSBS38_00725 BSBS38_00725 BSBS38_00725 676412 676783 + uncharacterized protein gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00725 BSBS38_00726 BSBS38_00726 BSBS38_00726 676849 677895 + uncharacterized protein gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00726 BSBS38_00727 BSBS38_00727 BSBS38_00727 677956 678756 - putative transposase-like protein Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00727 BSBS38_00728 BSBS38_00728 BSBS38_00728 678774 679106 - hypothetical protein gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00728 BSBS38_00729 BSBS38_00729 BSBS38_00729 679219 679377 - putative membrane protein YdzJ gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00729 BSBS38_00730 BSBS38_00730 BSBS38_00730 679567 679776 - uncharacterized protein gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00730 BSBS38_00731 BSBS38_00731 BSBS38_00731 679859 680674 - 3-oxoadipate enol-lactonase Belongs to the AB hydrolase superfamily%3B KEGG: lcb:LCABL_03550 3-oxoadipate enol-lactonase gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00731 BSBS38_00732 BSBS38_00732 BSBS38_00732 680687 681511 - uncharacterized protein gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00732 BSBS38_00733 BSBS38_00733 BSBS38_00733 681513 681674 - uncharacterized protein gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00733 BSBS38_00734 BSBS38_00734 BSBS38_00734 681773 683314 - Spore coat protein Involved in brown pigmentation during sporogenesis. To S. antibioticus phenoxazinone synthase (PhsA) gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00734 BSBS38_00735 BSBS38_00735 BSBS38_00735 683463 684872 - GABA permease High-affinity uptake system for GABA. Functions also as a low-affinity proline importer%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00735 BSBS38_00736 BSBS38_00736 BSBS38_00736 685269 686141 + putative transporter YeaB Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00736 BSBS38_00737 BSBS38_00737 BSBS38_00737 686292 687254 + uncharacterized protein Belongs to the MoxR family%3B KEGG: bsu:BSU06330 MoxR-like ATPase%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances%3B overlaps another CDS with the same product name gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00737 BSBS38_00738 BSBS38_00738 BSBS38_00738 687254 688450 + uncharacterized protein overlaps another CDS with the same product name gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00738 BSBS38_00739 BSBS38_00739 BSBS38_00739 688472 690685 + uncharacterized protein gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00739 BSBS38_00740 BSBS38_00740 guaA guaA 690839 692389 + GMP synthase (glutamine-hydrolyzing) Catalyzes the synthesis of GMP from XMP%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain%3B KEGG: bsr:I33_0720 GMP synthase (glutamine-hydrolysing) gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00740 BSBS38_00741 BSBS38_00741 BSBS38_00741 692498 693031 + RNA polymerase sigma factor SigV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin%2C paraquat and tellurite%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00741 BSBS38_00742 BSBS38_00742 BSBS38_00742 693013 694479 + hypothetical protein gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00742 BSBS38_00743 BSBS38_00743 BSBS38_00743 694864 696186 + Putative permease Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00743 BSBS38_00744 BSBS38_00744 BSBS38_00744 696397 697200 + uncharacterized protein gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00744 BSBS38_00745 BSBS38_00745 BSBS38_00745 697359 697526 + uncharacterized protein gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00745 BSBS38_00746 BSBS38_00746 BSBS38_00746 697740 698294 + UPF0316 protein Belongs to the UPF0316 family gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00746 BSBS38_00747 BSBS38_00747 BSBS38_00747 698294 698491 + uncharacterized protein gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00747 BSBS38_00748 BSBS38_00748 purE purE 698814 699302 + 5-(carboxyamino)imidazole ribonucleotide mutase In the C-terminal sectio%3B belongs to the AIR carboxylase family. Class I subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: sml:Smlt1613 5-(carboxyamino)imidazole ribonucleotide mutase gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00748 BSBS38_00749 BSBS38_00749 purK purK 699286 700437 + 5-(carboxyamino)imidazole ribonucleotide synthase Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: bsl:A7A1_3108 5-(carboxyamino)imidazole ribonucleotide synthase gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00749 BSBS38_00750 BSBS38_00750 purB purB 700434 701729 + Adenylosuccinate lyase Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability. Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily%3B KEGG: afe:Lferr_1990 adenylosuccinate lyase gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00750 BSBS38_00751 BSBS38_00751 purC purC 701803 702528 + Phosphoribosylaminoimidazolesuccinocarboxamide synthase Belongs to the SAICAR synthetase family%3B KEGG: bsu:BSU06450 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00751 BSBS38_00752 BSBS38_00752 purL purL 702521 702775 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the PurS family%3B KEGG: bsu:BSU06460 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00752 BSBS38_00753 BSBS38_00753 BSBS38_00753 702772 703455 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU06470 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00753 BSBS38_00754 BSBS38_00754 BSBS38_00754 703439 705667 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the FGAMS family%3B KEGG: bsu:BSU06480 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00754 BSBS38_00755 BSBS38_00755 purF purF 705643 707073 + Amidophosphoribosyltransferase Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine%3B In the C-terminal sectio%3B belongs to the purine/pyrimidine phosphoribosyltransferase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU06490 amidophosphoribosyltransferase gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00755 BSBS38_00756 BSBS38_00756 purM purM 707175 708215 + Phosphoribosylformylglycinamidine cyclo-ligase Belongs to the AIR synthase family%3B KEGG: azl:AZL_013100 phosphoribosylformylglycinamidine cyclo-ligase gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00756 BSBS38_00757 BSBS38_00757 purN purN 708212 708799 + Phosphoribosylglycinamide formyltransferase Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR)%2C producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate%3B Belongs to the GART family%3B KEGG: bsu:BSU06510 phosphoribosylglycinamide formyltransferase 1 gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00757 BSBS38_00758 BSBS38_00758 purH purH 708796 710334 + Phosphoribosylaminoimidazolecarboxamide formyltransferase Belongs to the PurH family%3B KEGG: bpn:BPEN_575 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00758 BSBS38_00759 BSBS38_00759 purD purD 710350 711618 + Phosphoribosylamine--glycine ligase Belongs to the GARS family%3B Contains 1 ATP-grasp domain%3B KEGG: pbr:PB2503_12869 phosphoribosylamine--glycine ligase gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00759 BSBS38_00760 BSBS38_00760 BSBS38_00760 711659 712078 - putative HTH-type transcriptional regulator YezC Contains 1 HTH asnC-type DNA-binding domain gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00760 BSBS38_00761 BSBS38_00761 BSBS38_00761 712222 713496 + putative amino acid permease YecA Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00761 BSBS38_00762 BSBS38_00762 BSBS38_00762 713511 713738 - putative membrane protein YezF gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00762 BSBS38_00763 BSBS38_00763 BSBS38_00763 713867 715609 + Adenine deaminase Belongs to the adenine deaminase family%3B KEGG: bsu:BSU06560 adenine deaminase gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00763 BSBS38_00764 BSBS38_00764 BSBS38_00764 715636 716631 + Putative lipoprotein YerB gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00764 BSBS38_00765 BSBS38_00765 BSBS38_00765 716634 716948 + uncharacterized protein gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00765 BSBS38_00766 BSBS38_00766 BSBS38_00766 716986 718563 - Glutamate synthase (ferredoxin) Belongs to the glutamate synthase family%3B KEGG: oih:OB3408 glutamate synthase (ferredoxin) gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00766 BSBS38_00767 BSBS38_00767 pcrB pcrB 718826 719512 + Heptaprenylglyceryl phosphate synthase Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepP%3B 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)%2C producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales%3B Belongs to the GGGP/HepGP synthase family%3B KEGG: bsu:BSU06600 putative glycerol-1-phosphate prenyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00767 BSBS38_00768 BSBS38_00768 uvrD uvrD 719574 721793 + DNA helicase DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsu:BSU06610 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00768 BSBS38_00769 BSBS38_00769 ligA ligA 721817 723823 + DNA ligase (NAD(+)) DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA%3B Belongs to the NAD-dependent DNA ligase family. LigA subfamily%3B Contains 1 BRCT domain%3B KEGG: bsu:BSU06620 DNA ligase (NAD+) gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00769 BSBS38_00770 BSBS38_00770 BSBS38_00770 723839 725029 + putative lipoprotein YerH gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00770 BSBS38_00771 BSBS38_00771 BSBS38_00771 725146 725478 + hypothetical protein gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00771 BSBS38_00772 BSBS38_00772 BSBS38_00772 725496 726296 + putative transposase-like protein Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00772 BSBS38_00773 BSBS38_00773 BSBS38_00773 726491 727492 + uncharacterized protein Belongs to the pseudomonas-type ThrB family gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00773 BSBS38_00774 BSBS38_00774 BSBS38_00774 727530 728222 - Protein SapB Belongs to the MgtC/SapB family gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00774 BSBS38_00775 BSBS38_00775 BSBS38_00775 728334 729812 - Osmoregulated proline transporter OpuE Catalyzes the uptake of extracellular proline under high-osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00775 BSBS38_00776 BSBS38_00776 gatC gatC 730226 730516 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatC family%3B KEGG: mmn:midi_00552 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00776 BSBS38_00777 BSBS38_00777 gatA gatA 730532 731989 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: bsu:BSU06680 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00777 BSBS38_00778 BSBS38_00778 gatB gatB 732003 733433 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)%3B Belongs to the GatB/GatE family. GatB subfamily%3B KEGG: pae:PA4484 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00778 BSBS38_00779 BSBS38_00779 BSBS38_00779 733470 734318 - putative HTH-type transcriptional regulator YerO Contains 1 HTH tetR-type DNA-binding domain gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00779 BSBS38_00780 BSBS38_00780 BSBS38_00780 734450 737608 + Swarming motility protein SwrC Required for self-resistance to surfactin%2C an antimicrobial lipopeptide surfactant produced by B. subtilis. Also required for swarming motility%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00780 BSBS38_00781 BSBS38_00781 dagK dagK 737760 738671 + Diacylglycerol kinase (ATP) Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway. Is more active toward long-chain DAG compared with short-chain DAG. Is not able to phosphorylate substrates other than DAG%2C such as monoacylglycerol%2C ceramide%2C undecaprenol%2C phosphatidylinositol%2C or sphingosine%3B Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: bsu:BSU06720 diacylglycerol kinase (ATP) gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00781 BSBS38_00782 BSBS38_00782 rumA rumA 738727 740103 + 23S rRNA (uracil(1939)-C(5))-methyltransferase Catalyzes the formation of 5-methyl-uridine at positions 747 (m5U747) and 1939 (m5U1939) in 23S rRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU06730 23S rRNA (uracil1939-C5)-methyltransferase gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00782 BSBS38_00783 BSBS38_00783 BSBS38_00783 741418 741627 - hypothetical protein gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00783 BSBS38_00784 BSBS38_00784 BSBS38_00784 741861 744878 + hypothetical protein gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00784 BSBS38_00785 BSBS38_00785 BSBS38_00785 745307 745504 - hypothetical protein gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00785 BSBS38_00786 BSBS38_00786 BSBS38_00786 746103 746576 - putative antitoxin YezG Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable) gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00786 BSBS38_00787 BSBS38_00787 BSBS38_00787 746581 748590 - Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00787 BSBS38_00788 BSBS38_00788 BSBS38_00788 748802 749779 + uncharacterized protein gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00788 BSBS38_00789 BSBS38_00789 rapH rapH 749988 751118 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU06830 response regulator aspartate phosphatase H%3B Acting on ester bonds gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00789 BSBS38_00790 BSBS38_00790 BSBS38_00790 751108 751281 + Phosphatase RapH inhibitor Inhibitor of the activity of phosphatase RapH. May inhibit the rapH promoter after import into the cytoplasm. Belongs to the phr family gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00790 BSBS38_00791 BSBS38_00791 BSBS38_00791 751441 752160 + putative transcriptional regulatory protein Belongs to the TACO1 family gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00791 BSBS38_00792 BSBS38_00792 BSBS38_00792 752294 752788 + Spore coat protein YeeK Part of the spore coat gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00792 BSBS38_00793 BSBS38_00793 BSBS38_00793 752903 753487 + putative HTH-type transcriptional regulator YezE Contains 1 HTH tetR-type DNA-binding domain gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00793 BSBS38_00794 BSBS38_00794 BSBS38_00794 753566 754009 + uncharacterized protein Belongs to the limonene-1%2C2-epoxide hydrolase family gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00794 BSBS38_00795 BSBS38_00795 BSBS38_00795 754006 754854 + Festuclavine dehydrogenase Belongs to the NmrA-type oxidoreductase family%3B KEGG: pbl:PAAG_05656 festuclavine dehydrogenase gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00795 BSBS38_00796 BSBS38_00796 BSBS38_00796 755000 755248 + Protein CotJA gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00796 BSBS38_00797 BSBS38_00797 BSBS38_00797 755232 755495 + Protein CotJB gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00797 BSBS38_00798 BSBS38_00798 BSBS38_00798 755510 756079 + Protein CotJC The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat. Belongs to the manganese catalase family gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00798 BSBS38_00799 BSBS38_00799 BSBS38_00799 756204 756746 + putative N-acetyltransferase YesJ Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK2822 null%3B Transferring groups other than amino-acyl groups gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00799 BSBS38_00800 BSBS38_00800 BSBS38_00800 757192 757815 + uncharacterized protein gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00800 BSBS38_00801 BSBS38_00801 yesM yesM 757812 759545 + Histidine kinase Member of the two-component regulatory system YesM/YesN. Probably activates YesN by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU06950 two-component system%2C sensor histidine kinase YesM gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00801 BSBS38_00802 BSBS38_00802 BSBS38_00802 759545 760072 + putative transcriptional regulatory protein YesN Member of the two-component regulatory system YesM/YesN%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B Contains 1 response regulatory domain%3B overlaps another CDS with the same product name gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00802 BSBS38_00803 BSBS38_00803 BSBS38_00803 760069 760650 + putative transcriptional regulatory protein YesN Member of the two-component regulatory system YesM/YesN%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B Contains 1 response regulatory domain%3B overlaps another CDS with the same product name gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00803 BSBS38_00804 BSBS38_00804 BSBS38_00804 760754 762037 + Putative ABC transporter substrate-binding protein YesO May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the bacterial solute-binding protein 1 family gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00804 BSBS38_00805 BSBS38_00805 BSBS38_00805 762034 762963 + putative ABC transporter permease protein YesP Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00805 BSBS38_00806 BSBS38_00806 BSBS38_00806 762967 763857 + putative ABC transporter permease protein YesQ Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00806 BSBS38_00807 BSBS38_00807 yteR yteR 763873 764907 + Unsaturated rhamnogalacturonyl hydrolase Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D- galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D- glucuronic acid at the non-reducing terminus%2C although the active pockets of YesR and UGL are very similar%3B Belongs to the glycosyl hydrolase 105 family%3B KEGG: bsu:BSU07000 unsaturated rhamnogalacturonyl hydrolase gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00807 BSBS38_00808 BSBS38_00808 BSBS38_00808 764930 767215 + HTH-type transcriptional regulator YesS Probable transcription factor regulating the pathway responsible for rhamnogalacturonan depolymerization. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00808 BSBS38_00809 BSBS38_00809 BSBS38_00809 767232 767927 + Rhamnogalacturonan acetylesterase RhgT May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity%2C and shows strong preference for glucose pentaacetate%2C beta-naphthylacetate%2C and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00809 BSBS38_00810 BSBS38_00810 BSBS38_00810 767920 768582 + uncharacterized protein overlaps another CDS with the same product name gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00810 BSBS38_00811 BSBS38_00811 BSBS38_00811 768579 769205 + uncharacterized protein overlaps another CDS with the same product name gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00811 BSBS38_00812 BSBS38_00812 yesW yesW 769344 771188 + Rhamnogalacturonan endolyase Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan%2C polygalacturonic acid%2C pectic acid and pectin%3B Belongs to the polysaccharide lyase 11 family%3B KEGG: bsn:BSn5_15425 rhamnogalacturonan endolyase gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00812 BSBS38_00813 BSBS38_00813 BSBS38_00813 771264 773072 + Rhamnogalacturonan endolyase Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan%2C polygalacturonic acid%2C pectic acid and pectin%3B Belongs to the polysaccharide lyase 11 family%3B KEGG: gsn:YC6258_00074 rhamnogalacturonan endolyase gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00813 BSBS38_00814 BSBS38_00814 rgaE rgaE 773230 773883 + Rhamnogalacturonan acetylesterase May play a role in the degradation of rhamnogalacturonan derived from plant cell walls. Probably has broad substrate specificity and may degrade several types of acetylated substrates%3B Belongs to the 'GDSL' lipolytic enzyme family%3B KEGG: adl:AURDEDRAFT_140474 rhamnogalacturonan acetylesterase gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00814 BSBS38_00815 BSBS38_00815 lacZ lacZ 773891 775882 + Beta-galactosidase May play a role in the degradation of rhamnogalacturonan derived from plant cell walls%3B Belongs to the glycosyl hydrolase 42 family%3B KEGG: bsu:BSU07080 beta-galactosidase gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00815 BSBS38_00816 BSBS38_00816 BSBS38_00816 775926 778499 + uncharacterized protein gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00816 BSBS38_00817 BSBS38_00817 BSBS38_00817 778621 780129 + Lipoprotein LipO gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00817 BSBS38_00818 BSBS38_00818 BSBS38_00818 780184 781140 + Protein LplB Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00818 BSBS38_00819 BSBS38_00819 BSBS38_00819 781154 782041 + Protein LplC Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00819 BSBS38_00820 BSBS38_00820 melA melA 782050 783390 + Alpha-galactosidase Alpha-galacturonidase able to catalyze the hydrolysis of the chromogenic substrate p-nitrophenyl-alpha-D-galacturonic acid (pNPalphaGalUA)%2C and of the probable natural substrate alpha-1%2C4- di-galacturonate (GalUA(2)). Can neither hydrolyze pNPbetaGalUA%2C nor the stereoisomeric pNPalphaGlcUA. Does not display alpha- or beta-glucosidase activity as it fails to hydrolyze melibiose%2C raffinose%2C lactose and the chromogenic analogs%2C pNPalphaGal and pNPbetaGal. Can not use the following compounds as substrates: pNP-N-acetyl-alpha- and beta-D-galactosaminide%2C pNP-N-acetyl- alpha- and beta-D-glucosaminide%2C pNP-alpha-L- and beta-L- arabinopyranoside%2C pNP-alpha- and beta-D-glucuronide%2C pNP-alpha- and beta-D-glucopyranoside%2C pNP-alpha- and beta-D-glucopyranoside 6-phosphate%2C pNP-alpha-D-galactopyranoside 6-phosphate and oNP- beta-D-galactopyranoside 6-phosphate%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bsr:I33_0804 alpha-galactosidase gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00820 BSBS38_00821 BSBS38_00821 BSBS38_00821 783465 784160 + UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00821 BSBS38_00822 BSBS38_00822 isdG isdG 784197 784523 - Heme oxygenase (staphylobilin-producing) Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase%2C with subsequent release of free iron%3B Belongs to the antibiotic biosynthesis monooxygenase family%3B Contains 1 ABM domain%3B KEGG: bsu:BSU07150 heme oxygenase (staphylobilin-producing) gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00822 BSBS38_00823 BSBS38_00823 glo1 glo1 784627 784989 - Lactoylglutathione lyase KEGG: bao:BAMF_2045 lactoylglutathione lyase gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00823 BSBS38_00824 BSBS38_00824 BSBS38_00824 785081 785575 - Glycine-rich cell wall structural protein Responsible for plasticity of the cell wall gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00824 BSBS38_00825 BSBS38_00825 BSBS38_00825 785773 786645 + RsbT co-antagonist protein RsbRB One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00825 BSBS38_00826 BSBS38_00826 BSBS38_00826 786800 786967 + uncharacterized protein gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00826 BSBS38_00827 BSBS38_00827 BSBS38_00827 787076 787720 + uncharacterized protein Belongs to the BI1 family gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00827 BSBS38_00828 BSBS38_00828 BSBS38_00828 787914 788126 + Putative oxidoreductase YetM gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00828 BSBS38_00829 BSBS38_00829 BSBS38_00829 788187 789047 - Putative transposase InsO for insertion sequence element IS911B Involved in the transposition of the insertion sequence IS911B. Contains 1 integrase catalytic domain gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00829 BSBS38_00830 BSBS38_00830 BSBS38_00830 789044 789376 - hypothetical protein gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00830 BSBS38_00831 BSBS38_00831 BSBS38_00831 789619 791088 + Retrotransposon-like protein Plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00831 BSBS38_00832 BSBS38_00832 BSBS38_00832 791152 792390 - Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00832 BSBS38_00833 BSBS38_00833 BSBS38_00833 792535 793608 - uncharacterized protein gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00833 BSBS38_00834 BSBS38_00834 BSBS38_00834 793753 796938 + Unspecific monooxygenase Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of long-chain fatty acids%2C with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 position. Also displays a NADPH- dependent reductase activity in the C-terminal domain%2C which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain (PubMed:15375636%2C PubMed:15122913). Is also able to catalyze efficient oxidation of sodium dodecyl sulfate (SDS) (PubMed:21048857)%3B In the N-terminal sectio%3B belongs to the cytochrome P450 family%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bsu:BSU07250 cytochrome P450 / NADPH-cytochrome P450 reductase gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00834 BSBS38_00835 BSBS38_00835 ltaS ltaS 797343 799304 + Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bsr:I33_0818 lipoteichoic acid synthase gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00835 BSBS38_00836 BSBS38_00836 hddC hddC 799540 800292 + D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase Catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate%3B Belongs to the glucose-1-phosphate cytidylyltransferase family%3B KEGG: cje:Cj1423c D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00836 BSBS38_00837 BSBS38_00837 rfbG rfbG 800365 801267 + CDP-glucose 4%2C6-dehydratase Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: bsr:I33_0820 CDP-glucose 4%2C6-dehydratase gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00837 BSBS38_00838 BSBS38_00838 BSBS38_00838 801291 801692 + uncharacterized protein gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00838 BSBS38_00839 BSBS38_00839 BSBS38_00839 801722 802201 + uncharacterized protein gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00839 BSBS38_00840 BSBS38_00840 tagF tagF 802230 803408 + CDP-glycerol glycerophosphotransferase Belongs to the glycosyltransferase 2 family%3B KEGG: bae:BATR1942_15750 CDP-glycerol glycerophosphotransferase gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00840 BSBS38_00841 BSBS38_00841 BSBS38_00841 803409 804344 + uncharacterized protein gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00841 BSBS38_00842 BSBS38_00842 BSBS38_00842 804374 805603 - putative MFS-type transporter YfnC Belongs to the major facilitator superfamily gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00842 BSBS38_00843 BSBS38_00843 BSBS38_00843 805715 806422 - (S)-2-haloacid dehalogenase Belongs to the HAD-like hydrolase superfamily. YjjG family%3B KEGG: bsu:BSU07330 2-haloacid dehalogenase gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00843 BSBS38_00844 BSBS38_00844 BSBS38_00844 806514 807899 - putative amino acid permease YfnA Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00844 BSBS38_00845 BSBS38_00845 BSBS38_00845 808149 809606 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU07350 aldehyde dehydrogenase (NAD+) gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00845 BSBS38_00846 BSBS38_00846 BSBS38_00846 809626 810480 + Putative sensory transducer protein YfmS Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation (By similarity)%3B Contains 1 methyl-accepting transducer domain gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00846 BSBS38_00847 BSBS38_00847 BSBS38_00847 810615 812504 + putative branched-chain amino acid transport ATP-binding protein LivG Probable component of a branched-chain amino-acid transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00847 BSBS38_00848 BSBS38_00848 BSBS38_00848 812627 813073 + uncharacterized protein gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00848 BSBS38_00849 BSBS38_00849 BSBS38_00849 813198 813620 + HTH-type transcriptional regulator YfmP Repressor of the yfmOP operon. A mutation in yfmP leads to overexpression of yfmO%2C probably causing a decrease in cellular copper that is eventually responsible for a reduced copper induction of copZA%3B Contains 1 HTH merR-type DNA-binding domain gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00849 BSBS38_00850 BSBS38_00850 BSBS38_00850 813686 814876 + Multidrug efflux protein YfmO Acts to efflux copper or a copper complex. It is possible that YfmO could contribute to copper resistance%3B Belongs to the major facilitator superfamily gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00850 BSBS38_00851 BSBS38_00851 BSBS38_00851 815068 815304 + uncharacterized protein gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00851 BSBS38_00852 BSBS38_00852 lptB lptB 815341 816897 - ABC-type transporter ATP-binding protein EcsA Has a role in exoprotein production%2C sporulation and competence. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: vpa:VP2669 lipopolysaccharide export system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00852 BSBS38_00853 BSBS38_00853 rok1 rok1 817070 818200 + RNA helicase A probable DEAD-box RNA helicase that plays a role in ribosomal 50S subunit assembly. May be a non-specific RNA helicase%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: tad:TRIADDRAFT_33010 ATP-dependent RNA helicase DDX52/ROK1 gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00853 BSBS38_00854 BSBS38_00854 BSBS38_00854 818269 818715 + putative N-acetyltransferase YfmK Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00854 BSBS38_00855 BSBS38_00855 BSBS38_00855 818832 820070 + Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00855 BSBS38_00856 BSBS38_00856 BSBS38_00856 820143 821162 - Putative NADP-dependent oxidoreductase YfmJ Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the NADP-dependent oxidoreductase L4BD family gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00856 BSBS38_00857 BSBS38_00857 BSBS38_00857 821266 822066 - Iron-chelate-transporting ATPase Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Responsible for energy coupling to the transport system (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU07490 iron complex transport system ATP-binding protein gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00857 BSBS38_00858 BSBS38_00858 BSBS38_00858 822079 823080 - Fe(3+)-citrate import system permease protein YfmE Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00858 BSBS38_00859 BSBS38_00859 BSBS38_00859 823077 824078 - Fe(3+)-citrate import system permease protein YfmD Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00859 BSBS38_00860 BSBS38_00860 BSBS38_00860 824151 825098 - Fe(3+)-citrate-binding protein YfmC Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of YfmDE (Probable)%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00860 BSBS38_00861 BSBS38_00861 BSBS38_00861 825207 825617 - uncharacterized protein gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00861 BSBS38_00862 BSBS38_00862 BSBS38_00862 825819 826166 + General stress protein 17M gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00862 BSBS38_00863 BSBS38_00863 BSBS38_00863 826356 827618 + Pectate lyase Produces unsaturated products from polygalacturonate. Belongs to the polysaccharide lyase 1 family%3B KEGG: bsu:BSU07560 pectate lyase gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00863 BSBS38_00864 BSBS38_00864 BSBS38_00864 827745 829181 + Putative malate transporter YflS Might be a malate transporter. Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. DIT1 subfamily gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00864 BSBS38_00865 BSBS38_00865 citS citS 829309 830937 + Histidine kinase Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU07580 two-component system%2C CitB family%2C sensor histidine kinase CitS gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00865 BSBS38_00866 BSBS38_00866 BSBS38_00866 830909 831589 + Transcriptional regulatory protein CitT Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon%3B Contains 1 response regulatory domain gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00866 BSBS38_00867 BSBS38_00867 BSBS38_00867 831592 832551 + UPF0065 protein YflP Belongs to the UPF0065 (bug) family gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00867 BSBS38_00868 BSBS38_00868 BSBS38_00868 832747 834048 + Mg(2+)/citrate complex secondary transporter Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+)%2C Mn(2+)%2C Co(2+)%2C and Zn(2+). Belongs to the CitM (TC 2. A. 11) transporter family gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00868 BSBS38_00869 BSBS38_00869 BSBS38_00869 834104 834898 + putative metallo-hydrolase YflN Belongs to the metallo-beta-lactamase superfamily gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00869 BSBS38_00870 BSBS38_00870 BSBS38_00870 835017 836108 + Nitric-oxide synthase (NAD(P)H) Catalyzes the production of nitric oxide%3B Belongs to the NOS family. Bacterial NOS oxygenase subfamily%3B KEGG: bsu:BSU07630 nitric-oxide synthase%2C bacterial gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00870 BSBS38_00871 BSBS38_00871 acyP acyP 836099 836374 - Acylphosphatase Belongs to the acylphosphatase family%3B Contains 1 acylphosphatase-like domain%3B KEGG: bsu:BSU07640 acylphosphatase gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00871 BSBS38_00872 BSBS38_00872 BSBS38_00872 836441 837106 + uncharacterized protein Contains 1 MOSC domain gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00872 BSBS38_00873 BSBS38_00873 BSBS38_00873 837147 837284 - uncharacterized protein gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00873 BSBS38_00874 BSBS38_00874 BSBS38_00874 837441 837596 - uncharacterized protein gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00874 BSBS38_00875 BSBS38_00875 BSBS38_00875 837703 838017 - uncharacterized protein gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00875 BSBS38_00876 BSBS38_00876 BSBS38_00876 838099 838848 - Methionyl aminopeptidase Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: ara:Arad_3299 methionyl aminopeptidase gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00876 BSBS38_00877 BSBS38_00877 nagE nagE 839020 840378 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport (By similarity)%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: xpo:XPG1_2405 PTS system%2C N-acetylglucosamine-specific IIB component gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00877 BSBS38_00878 BSBS38_00878 BSBS38_00878 840411 842360 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bsu:BSU07710 lipoteichoic acid synthase gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00878 BSBS38_00879 BSBS38_00879 BSBS38_00879 842617 843009 + uncharacterized protein gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00879 BSBS38_00880 BSBS38_00880 BSBS38_00880 843256 843561 - putative membrane protein YfkQ Belongs to the GerABKA family gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00880 BSBS38_00881 BSBS38_00881 treB treB 843770 845182 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in trehalose transport. Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU07800 PTS system%2C trehalose-specific IIB component gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00881 BSBS38_00882 BSBS38_00882 treC treC 845253 846938 + Alpha%2Calpha-phosphotrehalase Belongs to the glycosyl hydrolase 13 family%3B KEGG: xdo:XDD1_0104 trehalose-6-phosphate hydrolase gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00882 BSBS38_00883 BSBS38_00883 BSBS38_00883 846959 847675 + Trehalose operon transcriptional repressor Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate%2C which probably acts as an inducer. Contains 1 HTH gntR-type DNA-binding domain gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00883 BSBS38_00884 BSBS38_00884 BSBS38_00884 847815 848480 + Putative NAD(P)H nitroreductase YfkO Belongs to the nitroreductase family%3B KEGG: pmu:PM1832 null%3B Oxidoreductases gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00884 BSBS38_00885 BSBS38_00885 yfkN yfkN 848517 852905 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase Catalyzes the release of inorganic phosphate from 2'%2C3'- cyclic nucleotides through consecutive 2'%2C3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phosphate from 3'%2C5'-cyclic nucleotides. Probably plays a role in the cellular reprocessing of nucleotides present in the medium%2C under conditions of phosphate shortage%3B Belongs to the 5'-nucleotidase family%3B KEGG: bsu:BSU07840 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00885 BSBS38_00886 BSBS38_00886 pfpI pfpI 853148 853666 + General stress protein Functions in the protection against aldehyde-stress%2C possibly by degrading damaged proteins%3B Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: eco:b3153 protease I%3B Glycosylases gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00886 BSBS38_00887 BSBS38_00887 BSBS38_00887 853706 854896 - putative MFS-type transporter YfkL Belongs to the major facilitator superfamily gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00887 BSBS38_00888 BSBS38_00888 BSBS38_00888 855006 855221 - UPF0435 protein YfkK Belongs to the UPF0435 family gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00888 BSBS38_00889 BSBS38_00889 BSBS38_00889 855424 855894 + Protein-tyrosine-phosphatase Acts on tyrosine phosphorylated proteins%2C low-MW aryl phosphates and natural and synthetic acyl phosphates%3B Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: slo:Shew_1588 protein-tyrosine phosphatase gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00889 BSBS38_00890 BSBS38_00890 BSBS38_00890 855912 856232 + uncharacterized protein gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00890 BSBS38_00891 BSBS38_00891 BSBS38_00891 856256 857083 + Putative ribonuclease-like protein YfkH gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00891 BSBS38_00892 BSBS38_00892 BSBS38_00892 857134 857256 + hypothetical protein gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00892 BSBS38_00893 BSBS38_00893 BSBS38_00893 857280 858455 - putative MFS-type transporter YfkF Belongs to the major facilitator superfamily gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00893 BSBS38_00894 BSBS38_00894 BSBS38_00894 858623 859678 + Ca(2+)/H(+) antiporter ChaA Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium%3B Belongs to the sodium/potassium/calcium exchanger family. Cation/proton exchanger (CAX) (TC 2. A. 19. 2) subfamily gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00894 BSBS38_00895 BSBS38_00895 BSBS38_00895 859752 860543 + uncharacterized protein gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00895 BSBS38_00896 BSBS38_00896 BSBS38_00896 860582 861418 - putative MscS family protein YfkC May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00896 BSBS38_00897 BSBS38_00897 BSBS38_00897 861425 862546 - Putative protein YfkA Belongs to the radical SAM superfamily gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00897 BSBS38_00898 BSBS38_00898 BSBS38_00898 862691 862876 + uncharacterized protein gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00898 BSBS38_00899 BSBS38_00899 BSBS38_00899 862977 863768 + Peptidoglycan-N-acetylmuramic acid deacetylase PdaA Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in glycan strands of peptidoglycan%2C leading to the formation of muramic delta-lactam residues in spore cortex%2C after transpeptidation of deacetylated muramic acid residues. PdaA probably carries out both deacetylation and lactam ring formation and requires the product of CwlD activity on peptidoglycan as a substrate. Is required for germination. Cannot use chitin oligomer (hexa-N-acetylchitohexaose) as a substrate%3B Belongs to the polysaccharide deacetylase family%3B KEGG: bsu:BSU07980 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00899 BSBS38_00900 BSBS38_00900 mmsB mmsB 863805 864665 - 3-hydroxyisobutyrate dehydrogenase Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: tmb:Thimo_0135 3-hydroxyisobutyrate dehydrogenase gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00900 BSBS38_00901 BSBS38_00901 BSBS38_00901 864764 865723 - Putative metal ion transporter YfjQ Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00901 BSBS38_00902 BSBS38_00902 BSBS38_00902 865841 866704 + DNA-3-methyladenine glycosylase II Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine%2C O2- methylthymine%2C and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions%3B Belongs to the alkylbase DNA glycosidase AlkA family%3B KEGG: bsu:BSU08010 DNA-3-methyladenine glycosylase II gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00902 BSBS38_00903 BSBS38_00903 BSBS38_00903 866818 868218 + 23S rRNA (uracil(1939)-C(5))-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU08020 23S rRNA (uracil1939-C5)-methyltransferase gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00903 BSBS38_00904 BSBS38_00904 BSBS38_00904 868817 869101 + putative membrane protein YfzA gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00904 BSBS38_00905 BSBS38_00905 dusA dusA 869849 870826 + putative tRNA-dihydrouridine synthase Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: alt:ambt_00705 tRNA-dihydrouridine synthase A%3B Oxidoreductases gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00905 BSBS38_00906 BSBS38_00906 BSBS38_00906 871022 871474 + uncharacterized protein gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00906 BSBS38_00907 BSBS38_00907 BSBS38_00907 871504 872193 + uncharacterized protein gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00907 BSBS38_00908 BSBS38_00908 pdhA pdhA 872425 873426 + Pyruvate dehydrogenase (acetyl-transferring) Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde. The alpha subunit is probably the catalytic subunit of the enzyme (By similarity)%3B KEGG: bsu:BSU08060 pyruvate dehydrogenase E1 component alpha subunit gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00908 BSBS38_00909 BSBS38_00909 pdhB pdhB 873430 874458 + Pyruvate dehydrogenase (acetyl-transferring) Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde%3B KEGG: bsu:BSU08070 pyruvate dehydrogenase E1 component beta subunit gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00909 BSBS38_00910 BSBS38_00910 dlsT dlsT 874472 875668 + Dihydrolipoyllysine-residue succinyltransferase Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: rpr:RP179 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00910 BSBS38_00911 BSBS38_00911 pdhD pdhD 875689 877065 + Dihydrolipoyl dehydrogenase Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: ype:YPO3917 dihydrolipoamide dehydrogenase gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00911 BSBS38_00912 BSBS38_00912 BSBS38_00912 877182 878999 + Acetoin dehydrogenase operon transcriptional activator AcoR Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex%3B Contains 1 sigma-54 factor interaction domain gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00912 BSBS38_00913 BSBS38_00913 BSBS38_00913 879053 879232 + Small%2C acid-soluble spore protein H Belongs to the SspH family gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00913 BSBS38_00914 BSBS38_00914 BSBS38_00914 879268 879594 - UPF0060 membrane protein YfjF Belongs to the UPF0060 family gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00914 BSBS38_00915 BSBS38_00915 BSBS38_00915 879648 880190 - putative lipoprotein YfjD To B. subtilis YfjE gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00915 BSBS38_00916 BSBS38_00916 BSBS38_00916 880200 880757 - putative lipoprotein YfjD To B. subtilis YfjE gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00916 BSBS38_00917 BSBS38_00917 BSBS38_00917 880789 881556 - uncharacterized protein gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00917 BSBS38_00918 BSBS38_00918 BSBS38_00918 881568 882791 - uncharacterized protein gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00918 BSBS38_00919 BSBS38_00919 BSBS38_00919 882797 883111 - uncharacterized protein gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00919 BSBS38_00920 BSBS38_00920 glvA glvA 883447 884796 + Maltose-6'-phosphate glucosidase Hydrolyzes maltose-6'-phosphate and trehalose-6'- phosphate. Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent maltose phosphotransferase system (PEP-PTS). Is also able to significantly catalyze the hydrolysis of both 6-phospho-alpha- and 6-phospho- beta-glucosides containing activated leaving groups such as p- nitrophenol and does so with retention and inversion%2C respectively%2C of the substrate anomeric configuration. Belongs to the glycosyl hydrolase 4 family%3B KEGG: bsu:BSU08180 maltose-6'-phosphate glucosidase gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00920 BSBS38_00921 BSBS38_00921 BSBS38_00921 884861 885625 + HTH-type transcriptional regulator GlvR Positive regulator of the glv operon expression%2C which consists of GlvA%2C GlvR and GlvC%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00921 BSBS38_00922 BSBS38_00922 glvB glvB 885640 887223 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in maltose transport%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU08200 PTS system%2C arbutin-like IIB component gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00922 BSBS38_00923 BSBS38_00923 BSBS38_00923 887346 889679 + Pre-neck appendage protein gp12 Structural component of the 12 appendages that hang from the lower collar. Adhesion protein that binds to the host cell surface during virus attachment and mediates teichoic acids degradation%3B Contains 6 PbH1 repeats gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00923 BSBS38_00924 BSBS38_00924 BSBS38_00924 889804 891042 + Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00924 BSBS38_00925 BSBS38_00925 BSBS38_00925 891471 893192 + putative ABC transporter ATP-binding protein YfiB Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00925 BSBS38_00926 BSBS38_00926 BSBS38_00926 893186 895000 + putative ABC transporter ATP-binding protein YfiC Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00926 BSBS38_00927 BSBS38_00927 BSBS38_00927 895154 895558 + Putative oxidoreductase CatD Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the DoxX family gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00927 BSBS38_00928 BSBS38_00928 catE catE 895576 896433 + Catechol 2%2C3-dioxygenase Involved in the meta cleavage of catechol to 2- hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the extradiol ring-cleavage dioxygenase family%3B KEGG: bsu:BSU08240 catechol 2%2C3-dioxygenase gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00928 BSBS38_00929 BSBS38_00929 BSBS38_00929 896527 897471 + putative HTH-type transcriptional regulator YfiF Contains 1 HTH araC/xylS-type DNA-binding domain gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00929 BSBS38_00930 BSBS38_00930 BSBS38_00930 897646 899094 + Putative metabolite transport protein YfiG Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00930 BSBS38_00931 BSBS38_00931 iolE iolE 899121 900062 + Myo-inosose-2 dehydratase KEGG: eca:ECA1464 inosose dehydratase gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00931 BSBS38_00932 BSBS38_00932 BSBS38_00932 900075 900251 + putative oxidoreductase YfiI Belongs to the Gfo/Idh/MocA family gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00932 BSBS38_00933 BSBS38_00933 BSBS38_00933 900299 901303 + UDP-N-acetylglucosamine 3-dehydrogenase Belongs to the Gfo/Idh/MocA family%3B KEGG: mvn:Mevan_0204 UDP-N-acetylglucosamine 3-dehydrogenase gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00933 BSBS38_00934 BSBS38_00934 BSBS38_00934 901390 901506 + hypothetical protein gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00934 BSBS38_00935 BSBS38_00935 desK desK 901478 902629 + Histidine kinase Member of the two-component regulatory system YfiJ/YfiK. Probably activates YfiK by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: gag:Glaag_0450 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00935 BSBS38_00936 BSBS38_00936 cheB cheB 902626 903288 + Protein-glutamate methylesterase Member of the two-component regulatory system YfiJ/YfiK%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain%3B KEGG: hak:KO116_00752 two-component system%2C chemotaxis family%2C response regulator CheB gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00936 BSBS38_00937 BSBS38_00937 BSBS38_00937 903432 903842 + putative ABC transporter ATP-binding protein YfiL Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00937 BSBS38_00938 BSBS38_00938 BSBS38_00938 903839 904366 + putative ABC transporter ATP-binding protein YfiL Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00938 BSBS38_00939 BSBS38_00939 BSBS38_00939 904378 905568 + Putative transport permease YfiM Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00939 BSBS38_00940 BSBS38_00940 BSBS38_00940 905582 906739 + Putative transport permease YfiN Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00940 BSBS38_00941 BSBS38_00941 BSBS38_00941 906812 907360 - Negative transcription regulator PadR Negative transcriptional regulator of padC phenolic acid decarboxylase gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00941 BSBS38_00942 BSBS38_00942 BSBS38_00942 907653 908285 + Triacylglycerol lipase An esterase which preferentially hydrolyzes triacylglyceride substrates with short chain fatty acids (less than C10) with the maximum activity towards tricaprylin (C8:0). Active against p-nitrophenylesters with fatty acid chain lengths from C6 to C18. Belongs to the AB hydrolase superfamily%3B KEGG: bso:BSNT_01390 triacylglycerol lipase gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00942 BSBS38_00943 BSBS38_00943 BSBS38_00943 908474 909562 + Putative membrane-bound acyltransferase YfiQ Belongs to the acyltransferase 3 family gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00943 BSBS38_00944 BSBS38_00944 BSBS38_00944 909597 910214 - putative HTH-type transcriptional regulator YfiR Contains 1 HTH tetR-type DNA-binding domain gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00944 BSBS38_00945 BSBS38_00945 BSBS38_00945 910180 911433 - dTMP kinase Belongs to the major facilitator superfamily. TCR/Tet family%3B KEGG: abai:IMCC26256_11234 dTMP kinase gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00945 BSBS38_00946 BSBS38_00946 BSBS38_00946 911556 912092 + Putative metal-dependent hydrolase YfiT Possible metal-dependent hydrolase. Belongs to the metal hydrolase YfiT family gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00946 BSBS38_00947 BSBS38_00947 BSBS38_00947 912089 912703 - putative MFS-type transporter YfiU Belongs to the major facilitator superfamily. TCR/Tet family%3B overlaps another CDS with the same product name gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00947 BSBS38_00948 BSBS38_00948 BSBS38_00948 912700 913650 - putative MFS-type transporter YfiU Belongs to the major facilitator superfamily. TCR/Tet family%3B overlaps another CDS with the same product name gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00948 BSBS38_00949 BSBS38_00949 BSBS38_00949 913756 914238 - putative HTH-type transcriptional regulator YfiV Contains 1 HTH marR-type DNA-binding domain gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00949 BSBS38_00950 BSBS38_00950 mprF mprF 914410 916980 + Lysyltransferase Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG)%2C which produces lysylphosphatidylglycerol (LPG)%2C one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects B. subtilis against its own CAMPs and against those produced by competiting microorganisms (bacteriocins). In fact%2C the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides%3B Belongs to the LPG synthase family%3B KEGG: bsu:BSU08425 phosphatidylglycerol lysyltransferase gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00950 BSBS38_00951 BSBS38_00951 BSBS38_00951 916998 917975 - putative siderophore-binding lipoprotein YfiY Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable)%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00951 BSBS38_00952 BSBS38_00952 BSBS38_00952 918108 919109 + putative siderophore transport system permease protein YfiZ Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00952 BSBS38_00953 BSBS38_00953 BSBS38_00953 919106 920137 + putative siderophore transport system permease protein YfhA Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00953 BSBS38_00954 BSBS38_00954 phzF phzF 920252 921133 + Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Belongs to the PhzF family%3B KEGG: csn:Cyast_1801 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00954 BSBS38_00955 BSBS38_00955 bluB bluB 921221 921805 + 5%2C6-dimethylbenzimidazole synthase Belongs to the nitroreductase family%3B KEGG: nat:NJ7G_1056 5%2C6-dimethylbenzimidazole synthase gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00955 BSBS38_00956 BSBS38_00956 BSBS38_00956 921844 922035 - uncharacterized protein gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00956 BSBS38_00957 BSBS38_00957 BSBS38_00957 922102 922212 - uncharacterized protein gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00957 BSBS38_00958 BSBS38_00958 BSBS38_00958 922267 923178 - Epimerase family protein YfhF Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00958 BSBS38_00959 BSBS38_00959 BSBS38_00959 923267 924061 + Regulatory protein RecX Modulates RecA activity%3B Belongs to the RecX family gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00959 BSBS38_00960 BSBS38_00960 BSBS38_00960 924063 924383 + uncharacterized protein gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00960 BSBS38_00961 BSBS38_00961 BSBS38_00961 924394 924498 + hypothetical protein gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00961 BSBS38_00962 BSBS38_00962 BSBS38_00962 924519 925712 + putative MFS-type transporter YfhI Belongs to the major facilitator superfamily gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00962 BSBS38_00963 BSBS38_00963 BSBS38_00963 925744 925896 - Small%2C acid-soluble spore protein Belongs to the SspK family gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00963 BSBS38_00964 BSBS38_00964 BSBS38_00964 926021 926290 + uncharacterized protein gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00964 BSBS38_00965 BSBS38_00965 BSBS38_00965 926472 926732 + hypothetical protein gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00965 BSBS38_00966 BSBS38_00966 BSBS38_00966 926750 927550 + putative transposase-like protein Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00966 BSBS38_00967 BSBS38_00967 BSBS38_00967 927724 928242 + uncharacterized protein gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00967 BSBS38_00968 BSBS38_00968 BSBS38_00968 928267 928659 + uncharacterized protein gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00968 BSBS38_00969 BSBS38_00969 dhaA dhaA 928646 929506 + Haloalkane dehalogenase Belongs to the AB hydrolase superfamily. Epoxide hydrolase family%3B KEGG: sse:Ssed_1777 haloalkane dehalogenase gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00969 BSBS38_00970 BSBS38_00970 dpm1 dpm1 929736 930725 + Dolichyl-phosphate beta-D-mannosyltransferase Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: ban:BA_5684 dolichol-phosphate mannosyltransferase gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00970 BSBS38_00971 BSBS38_00971 BSBS38_00971 930797 933382 + uncharacterized protein gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00971 BSBS38_00972 BSBS38_00972 BSBS38_00972 933375 934358 - uncharacterized protein May act as a negative regulator for the transcription of yfhQ%2C fabL%2C sspE and yfhP gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00972 BSBS38_00973 BSBS38_00973 mutY mutY 934370 935683 + putative A/G-specific adenine glycosylase YfhQ Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7%2C8-dihydro-8- oxoguanine (By similarity)%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: bsut:BSUB_00937 A/G-specific adenine glycosylase%3B Hydrolyzing N-glycosyl compounds gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00973 BSBS38_00974 BSBS38_00974 BSBS38_00974 935691 935915 - uncharacterized protein gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00974 BSBS38_00975 BSBS38_00975 BSBS38_00975 935998 936750 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ahd:AI20_12755 3-oxoacyl-(acyl-carrier protein) reductase gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00975 BSBS38_00976 BSBS38_00976 BSBS38_00976 936819 937073 + Small%2C acid-soluble spore protein gamma-type SASP are proteins degraded in the first minutes of spore germination and provide amino acids for both new protein synthesis and metabolism. These proteins may be involved in dormant spore's high resistance to UV light. Belongs to the gamma-type SASP family gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00976 BSBS38_00977 BSBS38_00977 BSBS38_00977 937195 937506 + uncharacterized protein gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00977 BSBS38_00978 BSBS38_00978 BSBS38_00978 937650 938180 + UPF0374 protein Belongs to the UPF0374 family gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00978 BSBS38_00979 BSBS38_00979 msbA msbA 938268 940010 + Putative multidrug export ATP-binding/permease protein YgaD May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU08690 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00979 BSBS38_00980 BSBS38_00980 BSBS38_00980 940087 941196 - UPF0421 protein YgaE Belongs to the UPF0421 family gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00980 BSBS38_00981 BSBS38_00981 hemL hemL 941369 942658 - Glutamate-1-semialdehyde 2%2C1-aminomutase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bsu:BSU08710 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00981 BSBS38_00982 BSBS38_00982 prxQ prxQ 942810 943283 + Peroxiredoxin Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: cbu:CBU_0963 peroxiredoxin Q/BCP gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00982 BSBS38_00983 BSBS38_00983 BSBS38_00983 943406 943843 + Peroxide operon regulator Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA%2C ahpC%2C ahpF%2C the heme biosynthesis operon (hemAXCDBL)%2C fur%2C perR%2C zosA and mrgA. Belongs to the Fur family gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00983 BSBS38_00984 BSBS38_00984 BSBS38_00984 943878 944231 - UPF0295 protein Belongs to the UPF0295 family gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00984 BSBS38_00985 BSBS38_00985 BSBS38_00985 944439 945323 + uncharacterized protein gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00985 BSBS38_00986 BSBS38_00986 BSBS38_00986 945615 947164 + 16S ribosomal RNA rRNA gene985 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00986 BSBS38_00987 BSBS38_00987 BSBS38_00987 947335 950262 + 23S ribosomal RNA rRNA gene986 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00987 BSBS38_00988 BSBS38_00988 BSBS38_00988 950375 950490 + 5S ribosomal RNA rRNA gene987 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00988 BSBS38_00989 BSBS38_00989 BSBS38_00989 950500 950574 + tRNA-Asn tRNA gene988 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00989 BSBS38_00990 BSBS38_00990 BSBS38_00990 950580 950671 + tRNA-Ser tRNA gene989 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00990 BSBS38_00991 BSBS38_00991 BSBS38_00991 950706 950777 + tRNA-Glu tRNA gene990 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00991 BSBS38_00992 BSBS38_00992 BSBS38_00992 950787 950862 + tRNA-Val tRNA gene991 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00992 BSBS38_00993 BSBS38_00993 BSBS38_00993 950872 950948 + tRNA-Met tRNA gene992 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00993 BSBS38_00994 BSBS38_00994 BSBS38_00994 950960 951036 + tRNA-Asp tRNA gene993 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00994 BSBS38_00995 BSBS38_00995 BSBS38_00995 951049 951124 + tRNA-Phe tRNA gene994 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00995 BSBS38_00996 BSBS38_00996 BSBS38_00996 951130 951202 + tRNA-Thr tRNA gene995 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00996 BSBS38_00997 BSBS38_00997 BSBS38_00997 951225 951309 + tRNA-Tyr tRNA gene996 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00997 BSBS38_00998 BSBS38_00998 BSBS38_00998 951315 951388 + tRNA-Trp tRNA gene997 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00998 BSBS38_00999 BSBS38_00999 BSBS38_00999 951413 951488 + tRNA-His tRNA gene998 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_00999 BSBS38_01000 BSBS38_01000 BSBS38_01000 951498 951569 + tRNA-Gln tRNA gene999 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01000 BSBS38_01001 BSBS38_01001 BSBS38_01001 951619 951693 + tRNA-Gly tRNA gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01001 BSBS38_01002 BSBS38_01002 BSBS38_01002 951699 951769 + tRNA-Cys tRNA gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01002 BSBS38_01003 BSBS38_01003 BSBS38_01003 951777 951865 + tRNA-Leu tRNA gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01003 BSBS38_01004 BSBS38_01004 BSBS38_01004 952130 952211 + tRNA-Leu tRNA gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01004 BSBS38_01005 BSBS38_01005 BSBS38_01005 952290 953066 - Sporulation-control protein spo0M Controls the expression of spo0A and is required to pass the morphological stage 0 of sporulation%3B Belongs to the spo0M family gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01005 BSBS38_01006 BSBS38_01006 BSBS38_01006 953214 953411 + uncharacterized protein gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01006 BSBS38_01007 BSBS38_01007 pepN pepN 953811 954506 + Membrane alanyl aminopeptidase Belongs to the peptidase S51 family%3B KEGG: pmc:P9515_10721 aminopeptidase N gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01007 BSBS38_01008 BSBS38_01008 thiC thiC 954816 956588 + Phosphomethylpyrimidine synthase Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction%3B Belongs to the ThiC family%3B KEGG: bsu:BSU08790 phosphomethylpyrimidine synthase gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01008 BSBS38_01009 BSBS38_01009 BSBS38_01009 957110 957292 + Transcriptional regulatory protein SenN Regulates the expression of extracellular-protein genes of Bacillus natto. To B. subtilis SenS gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01009 BSBS38_01010 BSBS38_01010 katE katE 957334 958785 - Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: byi:BYI23_A003650 catalase gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01010 BSBS38_01011 BSBS38_01011 BSBS38_01011 959192 959959 + Aliphatic sulfonates import ATP-binding protein SsuB Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system (Probable). Is also involved in taurine transport%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01011 BSBS38_01012 BSBS38_01012 BSBS38_01012 959977 960966 + Putative aliphatic sulfonates-binding protein Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein. Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01012 BSBS38_01013 BSBS38_01013 BSBS38_01013 960963 961793 + Putative aliphatic sulfonates transport permease protein SsuC Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01013 BSBS38_01014 BSBS38_01014 ssuD ssuD 962056 962946 + Alkanesulfonate monooxygenase Catalyzes the desulfonation of aliphatic sulfonates. Shows highest activity with methanesulfonate%3B Belongs to the SsuD family%3B KEGG: ype:YPO3625 alkanesulfonate monooxygenase gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01014 BSBS38_01015 BSBS38_01015 BSBS38_01015 963079 963585 + uncharacterized protein gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01015 BSBS38_01016 BSBS38_01016 BSBS38_01016 963698 963967 + 30S ribosomal protein S14 Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01016 BSBS38_01017 BSBS38_01017 BSBS38_01017 963985 964458 - putative lipoprotein YgaO gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01017 BSBS38_01018 BSBS38_01018 BSBS38_01018 964460 964663 - putative HTH-type transcriptional regulator YgzD Contains 1 HTH cro/C1-type DNA-binding domain gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01018 BSBS38_01019 BSBS38_01019 BSBS38_01019 964854 964927 + tRNA-Gly tRNA gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01019 BSBS38_01020 BSBS38_01020 BSBS38_01020 965018 965641 - uncharacterized protein gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01020 BSBS38_01021 BSBS38_01021 queG queG 965723 966883 + Epoxyqueuosine reductase Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q)%2C which is a hypermodified base found in the wobble positions of tRNA(Asp)%2C tRNA(Asn)%2C tRNA(His) and tRNA(Tyr)%3B Belongs to the QueG family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B Contains 1 HEAT-like PBS-type repeat%3B KEGG: bsu:BSU08910 epoxyqueuosine reductase gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01021 BSBS38_01022 BSBS38_01022 BSBS38_01022 966962 967885 + uncharacterized protein gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01022 BSBS38_01023 BSBS38_01023 trmL trmL 967932 968405 + tRNA (cytidine(34)-2'-O)-methyltransferase Could methylate the ribose at the nucleotide 34 wobble position in tRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily%3B KEGG: gpb:HDN1F_07340 tRNA (cytidine/uridine-2'-O-)-methyltransferase gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01023 BSBS38_01024 BSBS38_01024 BSBS38_01024 968531 969172 + uncharacterized protein overlaps another CDS with the same product name gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01024 BSBS38_01025 BSBS38_01025 BSBS38_01025 969163 969876 + uncharacterized protein overlaps another CDS with the same product name gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01025 BSBS38_01026 BSBS38_01026 BSBS38_01026 969888 970595 + uncharacterized protein gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01026 BSBS38_01027 BSBS38_01027 BSBS38_01027 970945 972840 + Protein PrkA Belongs to the PrkA family gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01027 BSBS38_01028 BSBS38_01028 BSBS38_01028 973020 974198 + Stress response UPF0229 protein YhbH Belongs to the UPF0229 family gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01028 BSBS38_01029 BSBS38_01029 BSBS38_01029 974358 974822 + putative HTH-type transcriptional regulator YhbI Contains 1 HTH marR-type DNA-binding domain gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01029 BSBS38_01030 BSBS38_01030 BSBS38_01030 974891 975523 + Putative efflux system component YhbJ Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01030 BSBS38_01031 BSBS38_01031 BSBS38_01031 975564 977162 + putative MFS-type transporter YhcA Belongs to the major facilitator superfamily. EmrB family gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01031 BSBS38_01032 BSBS38_01032 wrbA wrbA 977185 977715 + NAD(P)H dehydrogenase (quinone) Contains 1 flavodoxin-like domain%3B KEGG: bsl:A7A1_3824 NAD(P)H dehydrogenase (quinone) gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01032 BSBS38_01033 BSBS38_01033 BSBS38_01033 977728 978102 + uncharacterized protein gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01033 BSBS38_01034 BSBS38_01034 BSBS38_01034 978262 979023 + uncharacterized protein gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01034 BSBS38_01035 BSBS38_01035 BSBS38_01035 979026 979391 + putative HTH-type transcriptional regulator YhcF Contains 1 HTH gntR-type DNA-binding domain gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01035 BSBS38_01036 BSBS38_01036 BSBS38_01036 979393 980091 + Iron-chelate-transporting ATPase Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3. A. 1. 6) family%3B Contains 1 ABC transporter domain%3B KEGG: pmu:PM0128 iron complex transport system ATP-binding protein gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01036 BSBS38_01037 BSBS38_01037 BSBS38_01037 980108 981025 + Monosaccharide-transporting ATPase Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: yen:YE0142 simple sugar transport system ATP-binding protein gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01037 BSBS38_01038 BSBS38_01038 BSBS38_01038 981018 981959 + uncharacterized protein gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01038 BSBS38_01039 BSBS38_01039 BSBS38_01039 982051 982254 - Cold shock protein CspB Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01039 BSBS38_01040 BSBS38_01040 BSBS38_01040 982679 983509 + putative lipoprotein YhcJ Belongs to the NlpA lipoprotein family gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01040 BSBS38_01041 BSBS38_01041 dge1 dge1 983512 984591 - Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: bsu:BSU09120 diguanylate cyclase gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01041 BSBS38_01042 BSBS38_01042 BSBS38_01042 984764 986155 + L-cystine uptake protein TcyP Mediates uptake of L-cystine%2C the oxidized form of L- cysteine. Although it is more specific for L-cystine%2C it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01042 BSBS38_01043 BSBS38_01043 BSBS38_01043 986482 988101 + Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01043 BSBS38_01044 BSBS38_01044 BSBS38_01044 988113 988529 + hypothetical protein gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01044 BSBS38_01045 BSBS38_01045 BSBS38_01045 988577 989206 - hypothetical protein gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01045 BSBS38_01046 BSBS38_01046 BSBS38_01046 989318 989800 - hypothetical protein gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01046 BSBS38_01047 BSBS38_01047 BSBS38_01047 989879 990088 - hypothetical protein gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01047 BSBS38_01048 BSBS38_01048 BSBS38_01048 990215 990919 - ICEBs1 integrase Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome%2C attB%2C and a site in the circular form of ICEBs1%2C attICEBs1%3B Belongs to the 'phage' integrase family gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01048 BSBS38_01049 BSBS38_01049 BSBS38_01049 991402 992298 - hypothetical protein gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01049 BSBS38_01050 BSBS38_01050 BSBS38_01050 992455 992754 + uncharacterized protein gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01050 BSBS38_01051 BSBS38_01051 BSBS38_01051 992940 993314 + hypothetical protein gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01051 BSBS38_01052 BSBS38_01052 BSBS38_01052 993412 993714 + hypothetical protein gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01052 BSBS38_01053 BSBS38_01053 BSBS38_01053 994170 994319 + hypothetical protein gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01053 BSBS38_01054 BSBS38_01054 BSBS38_01054 994347 995411 + uncharacterized protein gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01054 BSBS38_01055 BSBS38_01055 BSBS38_01055 995423 995671 + uncharacterized protein gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01055 BSBS38_01056 BSBS38_01056 BSBS38_01056 995684 996208 + uncharacterized protein overlaps another CDS with the same product name gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01056 BSBS38_01057 BSBS38_01057 BSBS38_01057 996198 997457 + uncharacterized protein overlaps another CDS with the same product name gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01057 BSBS38_01058 BSBS38_01058 BSBS38_01058 997560 998591 + uncharacterized protein gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01058 BSBS38_01059 BSBS38_01059 BSBS38_01059 998609 998935 + uncharacterized protein gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01059 BSBS38_01060 BSBS38_01060 BSBS38_01060 998948 999835 + putative membrane protein YddG overlaps another CDS with the same product name gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01060 BSBS38_01061 BSBS38_01061 BSBS38_01061 999832 1001385 + putative membrane protein YddG overlaps another CDS with the same product name gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01061 BSBS38_01062 BSBS38_01062 BSBS38_01062 1001382 1002371 + putative endopeptidase YddH Belongs to the peptidase C40 family%3B KEGG: eco:b1655 murein DD-endopeptidase%3B Acting on peptide bonds (peptidases) gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01062 BSBS38_01063 BSBS38_01063 BSBS38_01063 1002386 1002892 + uncharacterized protein gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01063 BSBS38_01064 BSBS38_01064 BSBS38_01064 1002955 1003338 + uncharacterized protein gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01064 BSBS38_01065 BSBS38_01065 BSBS38_01065 1003436 1004224 + hypothetical protein gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01065 BSBS38_01066 BSBS38_01066 BSBS38_01066 1004516 1005688 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU05010 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01066 BSBS38_01067 BSBS38_01067 BSBS38_01067 1005645 1005767 + hypothetical protein gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01067 BSBS38_01068 BSBS38_01068 BSBS38_01068 1005952 1006398 - uncharacterized protein gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01068 BSBS38_01069 BSBS38_01069 BSBS38_01069 1006548 1007123 + Lipoprotein YhcN gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01069 BSBS38_01070 BSBS38_01070 BSBS38_01070 1007244 1008257 + uncharacterized protein gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01070 BSBS38_01071 BSBS38_01071 BSBS38_01071 1008125 1008805 - Spore coat protein F-like protein YhcQ Belongs to the CotF family gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01071 BSBS38_01072 BSBS38_01072 BSBS38_01072 1008889 1012545 + Endonuclease YhcR Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected%2C using 5'-AMP as the substrate%2C in the presence of diverse divalent metals and with various pH values. In the C-terminal sectio%3B belongs to the 5'- nucleotidase family%3B Contains 1 TNase-like domain gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01072 BSBS38_01073 BSBS38_01073 srtA srtA 1012542 1013138 + Sortase A KEGG: bsu:BSU09200 sortase A gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01073 BSBS38_01074 BSBS38_01074 rluD rluD 1013168 1014076 - 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bsu:BSU09210 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01074 BSBS38_01075 BSBS38_01075 BSBS38_01075 1014187 1014582 + uncharacterized protein gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01075 BSBS38_01076 BSBS38_01076 BSBS38_01076 1014720 1015142 + IMP dehydrogenase Contains 2 CBS domains%3B KEGG: bsu:BSU09230 IMP dehydrogenase gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01076 BSBS38_01077 BSBS38_01077 BSBS38_01077 1015269 1015931 + uncharacterized protein Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01077 BSBS38_01078 BSBS38_01078 BSBS38_01078 1015947 1017488 + Hydrolase YhcX Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain%3B Contains 1 N-acetyltransferase domain gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01078 BSBS38_01079 BSBS38_01079 BSBS38_01079 1017921 1019258 + Glutamate-1-semialdehyde 2%2C1-aminomutase Essential for glycerol catabolism. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bpf:BpOF4_02380 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01079 BSBS38_01080 BSBS38_01080 BSBS38_01080 1019289 1019864 + Glycerol uptake operon antiterminator regulatory protein Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA. May also regulate expression of the glpFK operon gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01080 BSBS38_01081 BSBS38_01081 BSBS38_01081 1020043 1020867 + Glycerol uptake facilitator protein Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane. Belongs to the MIP/aquaporin (TC 1. A. 8) family gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01081 BSBS38_01082 BSBS38_01082 glpK glpK 1020886 1022376 + Glycerol kinase Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: csa:Csal_2104 glycerol kinase gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01082 BSBS38_01083 BSBS38_01083 glpA glpA 1022520 1024184 + Glycerol-3-phosphate dehydrogenase Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: bsu:BSU09300 glycerol-3-phosphate dehydrogenase gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01083 BSBS38_01084 BSBS38_01084 BSBS38_01084 1024316 1026061 + Phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosphate-dependent) Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG)%2C i. e. the predominant glycolipid found in B. subtilis membrane%2C which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers%2C since glucose-1-phosphate is the precursor of UDP-glucose%2C which serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required for biofilm formation. This is likely due to another role of UDP-glucose%2C which might also act as a metabolic signal regulating biofilm formation or may be involved in some unknown biosynthetic pathway essential for biofilm formation%2C e. g. the synthesis of an exopolysaccharide%3B Belongs to the phosphohexose mutase family%3B KEGG: bsu:BSU09310 phosphoglucomutase gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01084 BSBS38_01085 BSBS38_01085 BSBS38_01085 1026210 1027349 + Histidine kinase Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU09320 two-component system%2C NarL family%2C sensor kinase gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01085 BSBS38_01086 BSBS38_01086 BSBS38_01086 1027346 1027993 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01086 BSBS38_01087 BSBS38_01087 BSBS38_01087 1027990 1028514 + Azobenzene reductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH as an electron donor for its activity. Compounds with paired naphthalene groups coupled with the azo group are good substrates%2C with the following preference order: Rocceline > Sumifix Black B > Solar Orange. Belongs to the azoreductase type 2 family%3B KEGG: bsu:BSU09340 azobenzene reductase gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01087 BSBS38_01088 BSBS38_01088 BSBS38_01088 1028529 1028771 - uncharacterized protein gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01088 BSBS38_01089 BSBS38_01089 BSBS38_01089 1028972 1029295 + uncharacterized protein gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01089 BSBS38_01090 BSBS38_01090 lytF lytF 1029336 1030802 - D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS Probably functions as a cell separation enzyme in addition to LytE and LytF%3B Belongs to the peptidase C40 family%3B Contains 4 LysM repeats%3B KEGG: bsu:BSU09370 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01090 BSBS38_01091 BSBS38_01091 BSBS38_01091 1030954 1031394 - HTH-type transcriptional repressor NsrR Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01091 BSBS38_01092 BSBS38_01092 BSBS38_01092 1031501 1033027 - uncharacterized protein gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01092 BSBS38_01093 BSBS38_01093 BSBS38_01093 1033190 1034596 + Stage V sporulation protein Appears to be involved in spore cortex formation. To E. coli YcgB gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01093 BSBS38_01094 BSBS38_01094 BSBS38_01094 1034626 1036002 - Alkaline phosphatase Belongs to the alkaline phosphatase family%3B KEGG: bsu:BSU09410 alkaline phosphatase gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01094 BSBS38_01095 BSBS38_01095 BSBS38_01095 1036539 1037543 + putative peptidoglycan endopeptidase LytE Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan (By similarity). Seems to play a role in cell separation during vegetative growth%3B Belongs to the peptidase C40 family%3B Contains 3 LysM repeats%3B KEGG: bsu:BSU09420 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01095 BSBS38_01096 BSBS38_01096 BSBS38_01096 1037562 1038488 - HTH-type transcriptional regulator CitR Negative regulatory protein for the citA gene for citrate synthase I%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01096 BSBS38_01097 BSBS38_01097 gltA gltA 1038597 1039697 + Citrate (Si)-synthase Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. Belongs to the citrate synthase family%3B KEGG: bsu:BSU09440 citrate synthase gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01097 BSBS38_01098 BSBS38_01098 BSBS38_01098 1039771 1040640 + putative oxidoreductase YhdF Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02889 null%3B Oxidoreductases gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01098 BSBS38_01099 BSBS38_01099 BSBS38_01099 1040890 1042287 + putative amino acid permease YhdG Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01099 BSBS38_01100 BSBS38_01100 BSBS38_01100 1042406 1043761 + putative sodium-dependent transporter YhdH Putative sodium-dependent transporter%3B Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01100 BSBS38_01101 BSBS38_01101 BSBS38_01101 1043797 1045206 - putative HTH-type transcriptional regulator YdeL In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01101 BSBS38_01102 BSBS38_01102 BSBS38_01102 1045316 1045744 + putative N-acetyltransferase YhdJ Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK1891 null%3B Transferring groups other than amino-acyl groups gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01102 BSBS38_01103 BSBS38_01103 BSBS38_01103 1045775 1046065 - putative anti-sigma-M factor YhdK gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01103 BSBS38_01104 BSBS38_01104 BSBS38_01104 1046053 1047126 - putative anti-sigma-M factor YhdL gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01104 BSBS38_01105 BSBS38_01105 BSBS38_01105 1047119 1047610 - RNA polymerase sigma factor SigM Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt%2C acid and ethanol stress. Belongs to the sigma-70 factor family. ECF subfamily gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01105 BSBS38_01106 BSBS38_01106 BSBS38_01106 1047807 1048802 + Aryl-alcohol dehydrogenase (NADP(+)) Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: bur:Bcep18194_B0520 aryl-alcohol dehydrogenase (NADP+) gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01106 BSBS38_01107 BSBS38_01107 plsC plsC 1048937 1049536 + 1-acylglycerol-3-phosphate O-acyltransferase Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family%3B KEGG: bsu:BSU09540 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01107 BSBS38_01108 BSBS38_01108 BSBS38_01108 1049604 1050938 - UPF0053 protein YhdP Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01108 BSBS38_01109 BSBS38_01109 BSBS38_01109 1050999 1051544 - HTH-type transcriptional regulator CueR Transcriptional activator of the copZA operon%3B Contains 1 HTH merR-type DNA-binding domain gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01109 BSBS38_01110 BSBS38_01110 yhdR yhdR 1051587 1052036 + Aspartate transaminase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU09570 aspartate aminotransferase%3B overlaps another CDS with the same product name gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01110 BSBS38_01111 BSBS38_01111 BSBS38_01111 1052033 1052767 + Aspartate transaminase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU09570 aspartate aminotransferase%3B overlaps another CDS with the same product name gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01111 BSBS38_01112 BSBS38_01112 BSBS38_01112 1053094 1054479 + UPF0053 protein YhdT Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01112 BSBS38_01113 BSBS38_01113 BSBS38_01113 1054493 1054849 - Putative fluoride ion transporter CrcB Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family%3B overlaps another CDS with the same product name gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01113 BSBS38_01114 BSBS38_01114 BSBS38_01114 1054846 1055241 - Putative fluoride ion transporter CrcB Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family%3B overlaps another CDS with the same product name gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01114 BSBS38_01115 BSBS38_01115 BSBS38_01115 1055228 1055959 - Glycerophosphodiester phosphodiesterase Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to sn-glycerol 3-phosphate (G3P) and the corresponding alcohols%3B Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: fau:Fraau_3181 glycerophosphoryl diester phosphodiesterase gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01115 BSBS38_01116 BSBS38_01116 BSBS38_01116 1056193 1056300 + uncharacterized protein gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01116 BSBS38_01117 BSBS38_01117 BSBS38_01117 1056448 1057563 + putative MscS family protein YhdY May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01117 BSBS38_01118 BSBS38_01118 npdA npdA 1057633 1058376 + NAD-dependent protein deacylase NAD-dependent lysine demalonylase%2C desuccinylase and deglutarylase that specifically removes malonyl%2C succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activit%3B however this activity may not be physiologically relevant in vivo%3B Belongs to the sirtuin family. Class III subfamily%3B Contains 1 deacetylase sirtuin-type domain%3B KEGG: bsr:I33_1093 NAD-dependent deacetylase%3B In linear amides gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01118 BSBS38_01119 BSBS38_01119 deaA deaA 1058400 1059248 - Chitin disaccharide deacetylase Belongs to the polysaccharide deacetylase family%3B KEGG: sbl:Sbal_1411 chitin disaccharide deacetylase gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01119 BSBS38_01120 BSBS38_01120 BSBS38_01120 1059533 1060381 + D-amino-acid transaminase Acts on the D-isomers of alanine%2C leucine%2C aspartate%2C glutamate%2C aminobutyrate%2C norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction. The second half-reaction is the reverse of the first%2C transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D- amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate%2C which are essential bacterial cell wall components (By similarity)%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU09670 D-alanine transaminase gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01120 BSBS38_01121 BSBS38_01121 BSBS38_01121 1060424 1061785 - Na(+)/H(+) antiporter NhaC Is a secondary%2C electrogenic Na(+)/H(+) antiporter that catalyzes Na(+) uptake and proton efflux. Makes modest contributions to pH homeostasis in the alkaline range of pH but is not contributor to Na(+) resistance. Appears to have a repressive effect on growth and on alkaline phosphatases production in the presence of sodium%2C by affecting the transcription of the phoP/phoR two-component regulatory system. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01121 BSBS38_01122 BSBS38_01122 BSBS38_01122 1061912 1062412 - Stress response protein NhaX Belongs to the universal stress protein A family gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01122 BSBS38_01123 BSBS38_01123 BSBS38_01123 1062857 1064614 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheI Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01123 BSBS38_01124 BSBS38_01124 BSBS38_01124 1064611 1066632 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheH Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01124 BSBS38_01125 BSBS38_01125 BSBS38_01125 1066682 1067302 - uncharacterized protein gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01125 BSBS38_01126 BSBS38_01126 BSBS38_01126 1067571 1067774 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01126 BSBS38_01127 BSBS38_01127 BSBS38_01127 1067984 1068193 - uncharacterized protein gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01127 BSBS38_01128 BSBS38_01128 BSBS38_01128 1068352 1069713 - Endospore coat-associated protein YheD Involved in sporulation%3B Belongs to the YheC/YheD family gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01128 BSBS38_01129 BSBS38_01129 BSBS38_01129 1069703 1070794 - Endospore coat-associated protein YheC Involved in sporulation%3B Belongs to the YheC/YheD family gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01129 BSBS38_01130 BSBS38_01130 BSBS38_01130 1071061 1072194 + UPF0754 membrane protein Belongs to the UPF0754 family gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01130 BSBS38_01131 BSBS38_01131 BSBS38_01131 1072287 1072640 + UPF0342 protein YheA Belongs to the UPF0342 family gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01131 BSBS38_01132 BSBS38_01132 BSBS38_01132 1072684 1073757 - uncharacterized protein Contains 1 HEAT repeat gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01132 BSBS38_01133 BSBS38_01133 BSBS38_01133 1074243 1075109 + Stress response protein YhaX gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01133 BSBS38_01134 BSBS38_01134 hemN hemN 1075221 1076726 + Coproporphyrinogen dehydrogenase Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemZ subfamily%3B KEGG: bsu:BSU09840 oxygen-independent coproporphyrinogen III oxidase gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01134 BSBS38_01135 BSBS38_01135 BSBS38_01135 1076744 1077961 - K(+)/H(+) antiporter YhaU Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of KhtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium or lithium ions%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01135 BSBS38_01136 BSBS38_01136 BSBS38_01136 1077968 1078465 - K(+)/H(+) antiporter subunit KhtT Modulates the activity of the potassium/proton antiporter YhaU. The transporter is composed of the integral membrane protein YhaU and the regulatory protein KhtT%3B Contains 1 RCK C-terminal domain gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01136 BSBS38_01137 BSBS38_01137 BSBS38_01137 1078529 1078846 - uncharacterized protein gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01137 BSBS38_01138 BSBS38_01138 liuC liuC 1079033 1079800 + Methylglutaconyl-CoA hydratase Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: mro:MROS_2743 methylglutaconyl-CoA hydratase gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01138 BSBS38_01139 BSBS38_01139 BSBS38_01139 1079821 1080006 - uncharacterized protein gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01139 BSBS38_01140 BSBS38_01140 znuC znuC 1080133 1081029 + Phosphonates import ATP-binding protein PhnC Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: efe:EFER_1214 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01140 BSBS38_01141 BSBS38_01141 BSBS38_01141 1081022 1082281 + uncharacterized protein To M. jannaschii MJ1024 gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01141 BSBS38_01142 BSBS38_01142 BSBS38_01142 1082391 1083614 + putative metallophosphoesterase YhaO Belongs to the metallophosphoesterase superfamily gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01142 BSBS38_01143 BSBS38_01143 BSBS38_01143 1083628 1086510 + uncharacterized protein gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01143 BSBS38_01144 BSBS38_01144 cbf1 cbf1 1086584 1087528 + 3'-5' exoribonuclease YhaM Shows a 3'-5' exoribonuclease activity%3B Belongs to the YhaM family%3B Contains 1 HD domain%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU09930 3'-5' exoribonuclease%3B Acting on ester bonds gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01144 BSBS38_01145 BSBS38_01145 BSBS38_01145 1087653 1087865 + Sporulation protein YhaL Required for efficient sporulation gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01145 BSBS38_01146 BSBS38_01146 BSBS38_01146 1087906 1088790 - Peptidylprolyl isomerase Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo%3B Belongs to the PrsA family%3B Contains 1 PpiC domain%3B KEGG: bsu:BSU09950 foldase protein PrsA gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01146 BSBS38_01147 BSBS38_01147 BSBS38_01147 1089590 1090108 - putative membrane protein YhaJ gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01147 BSBS38_01148 BSBS38_01148 BSBS38_01148 1090325 1090657 + uncharacterized protein gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01148 BSBS38_01149 BSBS38_01149 BSBS38_01149 1090654 1091265 - HTH-type transcriptional regulator Hpr Negative regulator of protease production and sporulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01149 BSBS38_01150 BSBS38_01150 BSBS38_01150 1091444 1091845 - putative membrane protein YhaH gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01150 BSBS38_01151 BSBS38_01151 BSBS38_01151 1092196 1092714 - putative tryptophan transport protein Probably involved in tryptophan uptake. Belongs to the TrpP transporter family gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01151 BSBS38_01152 BSBS38_01152 serC serC 1092839 1093918 - Phosphoserine transaminase Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily%3B KEGG: bsu:BSU10020 phosphoserine aminotransferase gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01152 BSBS38_01153 BSBS38_01153 BSBS38_01153 1094065 1094502 - Protein hit Contains 1 HIT domain gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01153 BSBS38_01154 BSBS38_01154 BSBS38_01154 1094990 1095733 + Polar-amino-acid-transporting ATPase Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochrome%3B once thought to export heme%2C this seems not to be the case%2C but its exact role is uncertain. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. CcmA exporter (TC 3. A. 1. 107) family%3B Contains 1 ABC transporter domain%3B KEGG: cama:F384_08655 polar amino acid transport system ATP-binding protein gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01154 BSBS38_01155 BSBS38_01155 BSBS38_01155 1095726 1096952 + Protein EcsB Presumed to form part of an ABC-transporter%2C it may form a transport channel gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01155 BSBS38_01156 BSBS38_01156 BSBS38_01156 1096972 1097682 + Protein EcsC gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01156 BSBS38_01157 BSBS38_01157 BSBS38_01157 1097700 1098890 - Putative amidohydrolase YhaA Belongs to the peptidase M20A family%3B KEGG: bpu:BPUM_0954 amidohydrolase%3B In linear amides gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01157 BSBS38_01158 BSBS38_01158 BSBS38_01158 1098963 1100351 - putative membrane protein YhfA gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01158 BSBS38_01159 BSBS38_01159 BSBS38_01159 1100420 1100737 - uncharacterized protein gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01159 BSBS38_01160 BSBS38_01160 BSBS38_01160 1100782 1101282 - Heme-degrading monooxygenase HmoB Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase%2C with subsequent release of free iron%3B Belongs to the antibiotic biosynthesis monooxygenase family%3B Contains 1 ABM domain gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01160 BSBS38_01161 BSBS38_01161 BSBS38_01161 1101404 1103548 + Penicillin-binding protein 1F Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall. In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B KEGG: bsu:BSU10110 penicillin-binding protein 2A%3B Peptidoglycan glycosyltransferase gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01161 BSBS38_01162 BSBS38_01162 hemE hemE 1103670 1104731 + Uroporphyrinogen decarboxylase Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III%3B Belongs to the uroporphyrinogen decarboxylase family%3B KEGG: bsu:BSU10120 uroporphyrinogen decarboxylase gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01162 BSBS38_01163 BSBS38_01163 hemH hemH 1104803 1105735 + Protoporphyrin ferrochelatase Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: bsu:BSU10130 ferrochelatase gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01163 BSBS38_01164 BSBS38_01164 ppoX ppoX 1105750 1107162 + Protoporphyrinogen oxidase Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Also oxidizes the pathway intermediate coproporphyrinogen-III%3B Belongs to the protoporphyrinogen oxidase family%3B KEGG: bsu:BSU10140 oxygen-dependent protoporphyrinogen oxidase gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01164 BSBS38_01165 BSBS38_01165 BSBS38_01165 1107309 1107884 + putative HTH-type transcriptional regulator YhgD Contains 1 HTH tetR-type DNA-binding domain gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01165 BSBS38_01166 BSBS38_01166 BSBS38_01166 1107955 1110282 + uncharacterized protein To L. lactis phage infection protein (PIP) gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01166 BSBS38_01167 BSBS38_01167 fabH fabH 1110324 1111301 - Beta-ketoacyl-[acyl-carrier-protein] synthase III Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids%3B Belongs to the FabH family%3B KEGG: bsu:BSU10170 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01167 BSBS38_01168 BSBS38_01168 BSBS38_01168 1111429 1112205 + putative membrane protein YhfC gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01168 BSBS38_01169 BSBS38_01169 BSBS38_01169 1112265 1112483 + hypothetical protein gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01169 BSBS38_01170 BSBS38_01170 BSBS38_01170 1112617 1113657 + Putative aminopeptidase YhfE Belongs to the peptidase M42 family%3B KEGG: bce:BC0901 aminopeptidase%3B Aminopeptidases gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01170 BSBS38_01171 BSBS38_01171 BSBS38_01171 1113670 1114077 + uncharacterized protein gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01171 BSBS38_01172 BSBS38_01172 BSBS38_01172 1114115 1115404 - Proton/sodium-glutamate symport protein This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01172 BSBS38_01173 BSBS38_01173 BSBS38_01173 1115967 1116701 + putative metallo-hydrolase YhfI Belongs to the metallo-beta-lactamase superfamily gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01173 BSBS38_01174 BSBS38_01174 lplA lplA 1116714 1117709 + Lipoate--protein ligase Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to use octanoate as substrate%3B Belongs to the LplA family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU10250 lipoate-protein ligase A gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01174 BSBS38_01175 BSBS38_01175 codA codA 1117774 1118418 + Cytosine deaminase Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: sfa:Sfla_2548 cytosine deaminase gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01175 BSBS38_01176 BSBS38_01176 BSBS38_01176 1118488 1120077 + Long-chain-fatty-acid--CoA ligase Involved in the degradation of long-chain fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsr:I33_1159 long-chain acyl-CoA synthetase gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01176 BSBS38_01177 BSBS38_01177 BSBS38_01177 1120116 1120511 - uncharacterized protein gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01177 BSBS38_01178 BSBS38_01178 BSBS38_01178 1120660 1121940 + Ste24 endopeptidase Belongs to the peptidase M48B family%3B KEGG: psim:KR76_11030 STE24 endopeptidase gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01178 BSBS38_01179 BSBS38_01179 aprE aprE 1121979 1123124 - Subtilisin Subtilisin is an extracellular alkaline serine protease%2C it catalyzes the hydrolysis of proteins and peptide amides. Subtilisin NAT also has fibrinolytic activity. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU10300 subtilisin gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01179 BSBS38_01180 BSBS38_01180 BSBS38_01180 1123567 1124016 + putative N-acetyltransferase YhfO Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: btl:BALH_1988 null%3B Transferring groups other than amino-acyl groups gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01180 BSBS38_01181 BSBS38_01181 BSBS38_01181 1124088 1125080 + Alcohol dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily%3B KEGG: lsa:LSA1364 alcohol dehydrogenase gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01181 BSBS38_01182 BSBS38_01182 BSBS38_01182 1125297 1126268 + Putative ABC transporter substrate-binding lipoprotein YhfQ Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01182 BSBS38_01183 BSBS38_01183 BSBS38_01183 1126300 1126881 - putative phosphatase PhoE Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activity%3B Belongs to the phosphoglycerate mutase family. GpmB subfamily gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01183 BSBS38_01184 BSBS38_01184 atoB atoB 1126952 1128046 - Acetyl-CoA C-acetyltransferase May be involved in fatty acid metabolism. Belongs to the thiolase family%3B KEGG: bsu:BSU10350 acetyl-CoA C-acetyltransferase gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01184 BSBS38_01185 BSBS38_01185 BSBS38_01185 1128043 1129482 - Long-chain-fatty-acid--CoA ligase May be involved in fatty acid metabolism. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU10360 long-chain acyl-CoA synthetase gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01185 BSBS38_01186 BSBS38_01186 BSBS38_01186 1129489 1130049 - putative biotin transporter BioY Probable biotin transporter%3B Belongs to the BioY family gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01186 BSBS38_01187 BSBS38_01187 BSBS38_01187 1130184 1131482 - Heme-based aerotactic transducer HemAT Heme-containing signal transducer responsible for aerotaxis%2C the migratory response toward or away from oxygen%3B Contains 1 methyl-accepting transducer domain gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01187 BSBS38_01188 BSBS38_01188 BSBS38_01188 1131621 1132142 - Putative Rieske 2Fe-2S iron-sulfur protein YhfW Contains 1 Rieske domain%3B KEGG: ctc:CTC00417 null%3B With NAD(+) or NADP(+) as acceptor gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01188 BSBS38_01189 BSBS38_01189 BSBS38_01189 1132149 1132805 - Putative Rieske 2Fe-2S iron-sulfur protein YhfW Contains 1 Rieske domain%3B KEGG: ctc:CTC00417 null%3B With NAD(+) or NADP(+) as acceptor gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01189 BSBS38_01190 BSBS38_01190 puuB puuB 1132898 1133149 - Putative Rieske 2Fe-2S iron-sulfur protein YhfW Contains 1 Rieske domain%3B KEGG: rlt:Rleg2_0364 gamma-glutamylputrescine oxidase%3B With oxygen as acceptor gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01190 BSBS38_01191 BSBS38_01191 BSBS38_01191 1133253 1134110 + putative oxidoreductase YhxC Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU10400 null%3B Oxidoreductases gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01191 BSBS38_01192 BSBS38_01192 BSBS38_01192 1134138 1134371 - uncharacterized protein gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01192 BSBS38_01193 BSBS38_01193 BSBS38_01193 1134664 1135242 + Competence transcription factor Intermediate regulatory gene required for the expression of the late competence genes comC%2C comE%2C comG and the bdbDC operon. Receives signals from SrfA%2C and possibly other regulatory COM genes%2C and transduces these signals to the late COM genes gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01193 BSBS38_01194 BSBS38_01194 BSBS38_01194 1135287 1136186 - putative oxidoreductase YhxD Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU10430 null%3B Oxidoreductases gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01194 BSBS38_01195 BSBS38_01195 BSBS38_01195 1136403 1136672 + uncharacterized protein gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01195 BSBS38_01196 BSBS38_01196 BSBS38_01196 1136716 1138185 - putative symporter YhjB Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01196 BSBS38_01197 BSBS38_01197 BSBS38_01197 1138580 1138951 - uncharacterized protein gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01197 BSBS38_01198 BSBS38_01198 BSBS38_01198 1139103 1139726 + putative membrane protein YhjE gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01198 BSBS38_01199 BSBS38_01199 BSBS38_01199 1139728 1140234 + Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bsu:BSU10490 signal peptidase I gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01199 BSBS38_01200 BSBS38_01200 BSBS38_01200 1140417 1141913 + putative aromatic compound monooxygenase YhjG Belongs to the PheA/TfdB FAD monooxygenase family gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01200 BSBS38_01201 BSBS38_01201 BSBS38_01201 1141990 1142517 + putative HTH-type transcriptional regulator YhjH Contains 1 HTH marR-type DNA-binding domain gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01201 BSBS38_01202 BSBS38_01202 BSBS38_01202 1142544 1142741 - hypothetical protein gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01202 BSBS38_01203 BSBS38_01203 BSBS38_01203 1143134 1143316 - hypothetical protein gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01203 BSBS38_01204 BSBS38_01204 BSBS38_01204 1143406 1144626 - Glucose/mannose transporter GlcP Can transport glucose%2C mannose%2C 2-deoxyglucose and methyl alpha-glucoside%2C but not galactose%3B Belongs to the major facilitator superfamily gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01204 BSBS38_01205 BSBS38_01205 BSBS38_01205 1145141 1146379 + Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01205 BSBS38_01206 BSBS38_01206 ntdC ntdC 1146381 1147127 - Glucose-6-phosphate 3-dehydrogenase Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the oxidation of glucose 6-phosphate to 3-oxo-D-glucose 6-phosphate. It can only use NAD%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bsu:BSU10530 glucose-6-phosphate 3-dehydrogenase gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01206 BSBS38_01207 BSBS38_01207 ntdB ntdB 1147141 1147989 - Kanosamine-6-phosphate phosphatase Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the dephosphorylation of kanosamine 6- phosphate to yield kanosamine. There is a trace amount of activity using glucosamine-6-phosphate%3B Belongs to the HAD-like hydrolase superfamily. Cof family%3B KEGG: bsu:BSU10540 kanosamine-6-phosphate phosphatase gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01207 BSBS38_01208 BSBS38_01208 ntdA ntdA 1147961 1149286 - 3-dehydro-glucose-6-phosphate--glutamate transaminase Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the reversible pyridoxal phosphate- dependent transamination of 3-dehydro-alpha-D-glucose 6-phosphate to form alpha-D-kanosamine-6-phosphate. It can only use alpha- anomer and glutamate is the only amino donor%3B Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: bsu:BSU10550 3-dehydro-glucose-6-phosphate---glutamate transaminase gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01208 BSBS38_01209 BSBS38_01209 BSBS38_01209 1149390 1150379 + NTD biosynthesis operon regulator NtdR Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01209 BSBS38_01210 BSBS38_01210 BSBS38_01210 1150593 1151747 - uncharacterized protein Belongs to the AbrB family gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01210 BSBS38_01211 BSBS38_01211 BSBS38_01211 1151854 1153059 - putative MFS-type transporter YhjO Belongs to the major facilitator superfamily gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01211 BSBS38_01212 BSBS38_01212 BSBS38_01212 1153173 1154900 + uncharacterized protein In the C-terminal sectio%3B belongs to the bacterial solute-binding protein 5 family%3B Contains 1 HTH marR-type DNA-binding domain gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01212 BSBS38_01213 BSBS38_01213 BSBS38_01213 1155374 1155811 - uncharacterized protein gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01213 BSBS38_01214 BSBS38_01214 addB addB 1155995 1159495 + ATP-dependent helicase/deoxyribonuclease subunit The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent single-stranded exonuclease%2C acting in both directions. Recognizes the B. subtilis chi site (5'-AGCGG- 3') which transforms the enzyme from a helicase which degrades both DNA strands to one with only 5' to 3' exonuclease activity%3B this subunit has 5' -> 3' nuclease activity. RecA thread formation during DNA double- strand break repair requires RecJ or AddAB%3B Belongs to the helicase family. AddB/RexB type 1 subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsu:BSU10620 ATP-dependent helicase/nuclease subunit B%3B Acting on ester bonds gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01214 BSBS38_01215 BSBS38_01215 addA addA 1159482 1163180 + ATP-dependent helicase/nuclease subunit An essential component of the DNA double-stranded break repair machinery%2C the heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease. Recognizes the B. subtilis chi site (5'-AGCGG-3') which transforms the enzyme from a helicase which degrades both DNA strands to one with only 5' -> 3' exonuclease activity%3B this subunit has 3' -> 5' nuclease and helicase activity. RecA thread formation during DNA double-strand break repair requires RecJ or AddAB%3B Belongs to the helicase family. AddA subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsu:BSU10630 ATP-dependent helicase/nuclease subunit A%3B Acting on ester bonds gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01215 BSBS38_01216 BSBS38_01216 BSBS38_01216 1163252 1164427 + Nuclease SbcCD subunit SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SbcD family%3B overlaps another CDS with the same product name gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01216 BSBS38_01217 BSBS38_01217 BSBS38_01217 1164424 1167816 + Nuclease SbcCD subunit SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SMC family. SbcC subfamily%3B overlaps another CDS with the same product name gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01217 BSBS38_01218 BSBS38_01218 BSBS38_01218 1167830 1168132 + uncharacterized protein gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01218 BSBS38_01219 BSBS38_01219 BSBS38_01219 1168169 1168387 - putative spore germination protein GerPF Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01219 BSBS38_01220 BSBS38_01220 BSBS38_01220 1168419 1168820 - putative spore germination protein GerPE gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01220 BSBS38_01221 BSBS38_01221 BSBS38_01221 1168820 1168996 - putative spore germination protein GerPD gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01221 BSBS38_01222 BSBS38_01222 BSBS38_01222 1168993 1169610 - putative spore germination protein GerPC gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01222 BSBS38_01223 BSBS38_01223 BSBS38_01223 1169634 1169867 - putative spore germination protein GerPB gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01223 BSBS38_01224 BSBS38_01224 BSBS38_01224 1169882 1170103 - putative spore germination protein GerPA Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01224 BSBS38_01225 BSBS38_01225 BSBS38_01225 1170526 1170696 - Aspartyl-phosphate phosphatase YisI Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01225 BSBS38_01226 BSBS38_01226 BSBS38_01226 1170853 1171764 - Inner spore coat protein H-like protein Involved in the assembly of several proteins in the inner and outer layer of the spore coat%3B Belongs to the CotH family gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01226 BSBS38_01227 BSBS38_01227 BSBS38_01227 1171919 1172824 + Acylpyruvate hydrolase Belongs to the FAH family%3B KEGG: gyc:GYMC61_2313 acylpyruvate hydrolase gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01227 BSBS38_01228 BSBS38_01228 BSBS38_01228 1172940 1173296 + UPF0344 protein Belongs to the UPF0344 family gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01228 BSBS38_01229 BSBS38_01229 wprA wprA 1173464 1176148 + Cell wall-associated protease CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU10770 cell wall-associated protease%3B Serine endopeptidases gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01229 BSBS38_01230 BSBS38_01230 BSBS38_01230 1176179 1176736 - uncharacterized protein gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01230 BSBS38_01231 BSBS38_01231 asnB asnB 1176906 1178750 + Asparagine synthase (glutamine-hydrolyzing) Asparagine synthetase involved in sporulation. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: ppw:PputW619_2683 asparagine synthase (glutamine-hydrolysing) gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01231 BSBS38_01232 BSBS38_01232 crtB crtB 1178855 1179652 + 15-cis-phytoene synthase Belongs to the phytoene/squalene synthase family%3B KEGG: bsu:BSU10810 phytoene synthase gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01232 BSBS38_01233 BSBS38_01233 BSBS38_01233 1179690 1181057 - putative transporter YisQ Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01233 BSBS38_01234 BSBS38_01234 BSBS38_01234 1181181 1182044 + putative HTH-type transcriptional regulator YisR Contains 1 HTH araC/xylS-type DNA-binding domain gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01234 BSBS38_01235 BSBS38_01235 BSBS38_01235 1182062 1183075 + HTH-type transcriptional regulator DegA Involved in the control of degradation of B. subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease. Contains 1 HTH lacI-type DNA-binding domain gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01235 BSBS38_01236 BSBS38_01236 iolX iolX 1183285 1184313 + Scyllo-inositol 2-dehydrogenase (NAD(+)) Catalyzes the NAD(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bsu:BSU10850 scyllo-inositol 2-dehydrogenase (NAD+) gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01236 BSBS38_01237 BSBS38_01237 BSBS38_01237 1184365 1184874 - uncharacterized protein Belongs to the DinB family gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01237 BSBS38_01238 BSBS38_01238 BSBS38_01238 1184924 1185535 - Putative amino-acid transporter YisU Belongs to the LysE/ArgO transporter (TC 2. A. 75) family gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01238 BSBS38_01239 BSBS38_01239 BSBS38_01239 1185659 1187101 + putative HTH-type transcriptional regulator YisV In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01239 BSBS38_01240 BSBS38_01240 BSBS38_01240 1187109 1187747 - uncharacterized protein Contains 3 pentapeptide repeat domains gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01240 BSBS38_01241 BSBS38_01241 BSBS38_01241 1187953 1188759 + Chloride peroxidase Belongs to the AB hydrolase superfamily%3B KEGG: gox:GOX1766 non-heme chloroperoxidase gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01241 BSBS38_01242 BSBS38_01242 cysC cysC 1188787 1189386 - Adenylyl-sulfate kinase Catalyzes the synthesis of activated sulfate%3B Belongs to the APS kinase family%3B KEGG: bsu:BSU10910 adenylylsulfate kinase gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01242 BSBS38_01243 BSBS38_01243 met3 met3 1189715 1190551 - Sulfate adenylyltransferase Belongs to the sulfate adenylyltransferase family%3B KEGG: bsu:BSU10920 sulfate adenylyltransferase gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01243 BSBS38_01244 BSBS38_01244 cysH cysH 1190664 1191374 - Phosphoadenylyl-sulfate reductase (thioredoxin) Reduction of activated sulfate into sulfite%3B Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: bsu:BSU10930 phosphoadenosine phosphosulfate reductase gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01244 BSBS38_01245 BSBS38_01245 comB comB 1191562 1192248 + 2-phosphosulfolactate phosphatase Belongs to the ComB family%3B KEGG: bsu:BSU10940 2-phosphosulfolactate phosphatase gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01245 BSBS38_01246 BSBS38_01246 comA comA 1192245 1193003 + Phosphosulfolactate synthase Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL) (By similarity). Is probably involved in the biosynthesis of L-sulfolactate%2C which is a major constituent of sporulating cells and mature spores%3B Belongs to the phosphosulfolactate synthase family%3B KEGG: bsu:BSU10950 phosphosulfolactate synthase gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01246 BSBS38_01247 BSBS38_01247 BSBS38_01247 1193048 1193677 - UPF0750 membrane protein YitE Belongs to the UPF0750 family gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01247 BSBS38_01248 BSBS38_01248 BSBS38_01248 1193773 1194888 - Putative isomerase YitF Belongs to the mandelate racemase/muconate lactonizing enzyme family%3B KEGG: bss:BSUW23_05560 D-galactarolactone cycloisomerase%3B Intramolecular lyases gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01248 BSBS38_01249 BSBS38_01249 BSBS38_01249 1194897 1196165 - putative MFS-type transporter YitG Belongs to the major facilitator superfamily gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01249 BSBS38_01250 BSBS38_01250 BSBS38_01250 1196277 1197125 - putative N-acetyltransferase YitH Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bce:BC1593 null%3B Transferring groups other than amino-acyl groups gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01250 BSBS38_01251 BSBS38_01251 BSBS38_01251 1197130 1197579 - putative N-acetyltransferase YitI Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bba:Bd0335 null%3B Transferring groups other than amino-acyl groups gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01251 BSBS38_01252 BSBS38_01252 BSBS38_01252 1197670 1199508 - Homocysteine S-methyltransferase In the C-terminal sectio%3B belongs to the methylenetetrahydrofolate reductase family%3B Contains 1 Hcy-binding domain%3B KEGG: bsu:BSU11010 homocysteine S-methyltransferase gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01252 BSBS38_01253 BSBS38_01253 BSBS38_01253 1199822 1200313 - UPF0234 protein Belongs to the UPF0234 family gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01253 BSBS38_01254 BSBS38_01254 BSBS38_01254 1200460 1201308 + uncharacterized protein Contains 1 S1 motif domain gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01254 BSBS38_01255 BSBS38_01255 BSBS38_01255 1201361 1201945 - uncharacterized protein overlaps another CDS with the same product name gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01255 BSBS38_01256 BSBS38_01256 BSBS38_01256 1201942 1202871 - uncharacterized protein overlaps another CDS with the same product name gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01256 BSBS38_01257 BSBS38_01257 BSBS38_01257 1202856 1203392 - uncharacterized protein overlaps another CDS with the same product name gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01257 BSBS38_01258 BSBS38_01258 BSBS38_01258 1203570 1203917 + Putative DNA-binding protein YizB gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01258 BSBS38_01259 BSBS38_01259 BSBS38_01259 1203914 1204501 + uncharacterized protein gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01259 BSBS38_01260 BSBS38_01260 BSBS38_01260 1204521 1204814 + uncharacterized protein gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01260 BSBS38_01261 BSBS38_01261 nprB nprB 1204950 1206566 + Neutral protease Belongs to the peptidase M4 family%3B KEGG: bsu:BSU11100 neutral peptidase B%3B Metalloendopeptidases gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01261 BSBS38_01262 BSBS38_01262 BSBS38_01262 1206613 1207464 - DegV domain-containing protein YitS May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01262 BSBS38_01263 BSBS38_01263 BSBS38_01263 1207601 1208443 + UPF0750 membrane protein YitT Belongs to the UPF0750 family gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01263 BSBS38_01264 BSBS38_01264 BSBS38_01264 1208462 1208917 + Intracellular proteinase inhibitor gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01264 BSBS38_01265 BSBS38_01265 BSBS38_01265 1208948 1209094 - uncharacterized protein gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01265 BSBS38_01266 BSBS38_01266 BSBS38_01266 1209146 1209298 - hypothetical protein gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01266 BSBS38_01267 BSBS38_01267 BSBS38_01267 1209402 1210214 - Putative phosphatase YitU Belongs to the HAD-like hydrolase superfamily. Cof family gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01267 BSBS38_01268 BSBS38_01268 BSBS38_01268 1210335 1211102 + Putative esterase gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01268 BSBS38_01269 BSBS38_01269 BSBS38_01269 1211166 1211474 + MIP18 family protein YitW Belongs to the MIP18 family gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01269 BSBS38_01270 BSBS38_01270 BSBS38_01270 1211539 1211709 + hypothetical protein gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01270 BSBS38_01271 BSBS38_01271 glcD glcD 1211771 1213201 + (S)-2-hydroxy-acid oxidase Belongs to the oxygen-dependent FAD-linked oxidoreductase family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: aur:HMPREF9243_0004 glycolate oxidase gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01271 BSBS38_01272 BSBS38_01272 BSBS38_01272 1213201 1213557 + putative MFS-type transporter YitZ Belongs to the major facilitator superfamily gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01272 BSBS38_01273 BSBS38_01273 argC argC 1213946 1214983 + N-acetyl-gamma-glutamyl-phosphate reductase Belongs to the NAGSA dehydrogenase family. Type 1 subfamily%3B KEGG: hhc:M911_03575 N-acetyl-gamma-glutamyl-phosphate reductase gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01273 BSBS38_01274 BSBS38_01274 argJ argJ 1215003 1216223 + Glutamate N-acetyltransferase Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor%2C and of ornithine by transacetylation between N(2)-acetylornithine and glutamate%3B Belongs to the ArgJ family%3B KEGG: bsu:BSU11200 glutamate N-acetyltransferase / amino-acid N-acetyltransferase gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01274 BSBS38_01275 BSBS38_01275 argB argB 1216238 1217014 + Acetylglutamate kinase Belongs to the acetylglutamate kinase family%3B KEGG: bsu:BSU11210 acetylglutamate kinase gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01275 BSBS38_01276 BSBS38_01276 argD argD 1217011 1218168 + Acetylornithine transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily%3B KEGG: bsu:BSU11220 acetylornithine aminotransferase gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01276 BSBS38_01277 BSBS38_01277 carA carA 1218239 1219300 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bba:Bd0856 carbamoyl-phosphate synthase small subunit%3B overlaps another CDS with the same product name gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01277 BSBS38_01278 BSBS38_01278 carB carB 1219293 1222130 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: bsu:BSU11240 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01278 BSBS38_01279 BSBS38_01279 BSBS38_01279 1222097 1222384 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: bsu:BSU11240 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01279 BSBS38_01280 BSBS38_01280 argF argF 1222372 1223331 + Ornithine carbamoyltransferase Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: bsu:BSU11250 ornithine carbamoyltransferase gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01280 BSBS38_01281 BSBS38_01281 BSBS38_01281 1223379 1224179 - putative transposase-like protein Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01281 BSBS38_01282 BSBS38_01282 BSBS38_01282 1224197 1224529 - hypothetical protein gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01282 BSBS38_01283 BSBS38_01283 BSBS38_01283 1224707 1224886 + uncharacterized protein gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01283 BSBS38_01284 BSBS38_01284 BSBS38_01284 1224933 1225118 - putative membrane protein YjzD gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01284 BSBS38_01285 BSBS38_01285 BSBS38_01285 1225367 1226101 + uncharacterized protein gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01285 BSBS38_01286 BSBS38_01286 BSBS38_01286 1226183 1226740 + uncharacterized protein gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01286 BSBS38_01287 BSBS38_01287 BSBS38_01287 1226831 1227784 + Transcriptional activator protein med Positive activator of the comK gene. Belongs to the BMP lipoprotein family gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01287 BSBS38_01288 BSBS38_01288 BSBS38_01288 1227799 1227990 + ComG operon repressor Negatively regulates the transcription of the comG operon gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01288 BSBS38_01289 BSBS38_01289 BSBS38_01289 1228020 1228253 - uncharacterized protein gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01289 BSBS38_01290 BSBS38_01290 BSBS38_01290 1228424 1229362 + Beta-ketoacyl-[acyl-carrier-protein] synthase III Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for branched chain acyl-CoA%2C determining the biosynthesis of branched-chain of fatty acids instead of straight-chain%3B Belongs to the FabH family%3B KEGG: bsu:BSU11330 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01290 BSBS38_01291 BSBS38_01291 fabF fabF 1229385 1230626 + Beta-ketoacyl-[acyl-carrier-protein] synthase II Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP%3B Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: eco:b1095 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01291 BSBS38_01292 BSBS38_01292 BSBS38_01292 1230702 1231487 + uncharacterized protein gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01292 BSBS38_01293 BSBS38_01293 nrtC nrtC 1231679 1232665 + Oligopeptide transport ATP-binding protein AppD This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: eta:ETA_17200 nitrate/nitrite transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01293 BSBS38_01294 BSBS38_01294 BSBS38_01294 1232662 1233651 + Oligopeptide transport ATP-binding protein AppF This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01294 BSBS38_01295 BSBS38_01295 BSBS38_01295 1233739 1235370 + Oligopeptide-binding protein AppA This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence. AppA can bind and transport tetra- and pentapeptides but not tripeptides. Belongs to the bacterial solute-binding protein 5 family gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01295 BSBS38_01296 BSBS38_01296 BSBS38_01296 1235446 1236396 + Oligopeptide transport system permease protein AppB This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01296 BSBS38_01297 BSBS38_01297 BSBS38_01297 1236413 1237324 + Oligopeptide transport system permease protein AppC This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01297 BSBS38_01298 BSBS38_01298 BSBS38_01298 1237530 1238282 + UPF0736 protein Belongs to the UPF0736 family gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01298 BSBS38_01299 BSBS38_01299 warS warS 1238317 1239309 - Tryptophan--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU11420 tryptophanyl-tRNA synthetase gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01299 BSBS38_01300 BSBS38_01300 BSBS38_01300 1240053 1241690 + Oligopeptide-binding protein OppA This protein is a component of the oligopeptide permease%2C a binding protein-dependent transport system%2C It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence. Belongs to the bacterial solute-binding protein 5 family gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01300 BSBS38_01301 BSBS38_01301 BSBS38_01301 1241798 1242733 + Dipeptide transport system permease protein DppB Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01301 BSBS38_01302 BSBS38_01302 BSBS38_01302 1242737 1243654 + Oligopeptide transport system permease protein OppC Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01302 BSBS38_01303 BSBS38_01303 BSBS38_01303 1243668 1244735 + Oligopeptide transport ATP-binding protein OppD Part of the binding protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Required for sporulation and competence. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01303 BSBS38_01304 BSBS38_01304 BSBS38_01304 1244737 1245654 + Oligopeptide transport ATP-binding protein AmiF Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01304 BSBS38_01305 BSBS38_01305 BSBS38_01305 1245717 1246979 + putative MFS-type transporter YjbB Belongs to the major facilitator superfamily gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01305 BSBS38_01306 BSBS38_01306 BSBS38_01306 1247144 1247722 + Putative acetyltransferase YjbC Contains 1 N-acetyltransferase domain gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01306 BSBS38_01307 BSBS38_01307 BSBS38_01307 1247903 1248298 + Regulatory protein Spx Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis%2C during periods of extreme stress%3B Belongs to the ArsC family. Spx subfamily gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01307 BSBS38_01308 BSBS38_01308 BSBS38_01308 1248341 1248997 - putative membrane protein YjbE Belongs to the TerC family gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01308 BSBS38_01309 BSBS38_01309 BSBS38_01309 1249274 1249930 + Adapter protein MecA Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01309 BSBS38_01310 BSBS38_01310 BSBS38_01310 1250091 1251242 + Putative competence protein CoiA Required for optimal transformation gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01310 BSBS38_01311 BSBS38_01311 pepF pepF 1251289 1253301 + Oligoendopeptidase F like protein Belongs to the peptidase M3B family%3B KEGG: bsu:BSU11540 oligoendopeptidase F%3B Metalloendopeptidases gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01311 BSBS38_01312 BSBS38_01312 BSBS38_01312 1253339 1253506 - putative membrane protein YizD gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01312 BSBS38_01313 BSBS38_01313 BSBS38_01313 1253821 1254720 - UPF0413 protein YjbH Belongs to the UPF0413 family gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01313 BSBS38_01314 BSBS38_01314 BSBS38_01314 1254717 1255115 - Group 2 truncated hemoglobin YjbI Hemoglobin-like protein that exhibits a low peroxidase activity. Its very high oxygen affinity may rule out the possibility that it is involved in oxygen transport%3B Belongs to the truncated hemoglobin family. Group II subfamily gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01314 BSBS38_01315 BSBS38_01315 BSBS38_01315 1255370 1256104 - Putative murein lytic transglycosylase YjbJ Belongs to the transglycosylase Slt family gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01315 BSBS38_01316 BSBS38_01316 BSBS38_01316 1256119 1256691 - Glutathione transferase Contains 1 CYTH domain%3B KEGG: sar:SAR0971 glutathione S-transferase gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01316 BSBS38_01317 BSBS38_01317 BSBS38_01317 1256816 1257184 + UPF0738 protein YjbL Belongs to the UPF0738 family gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01317 BSBS38_01318 BSBS38_01318 BSBS38_01318 1257213 1257848 + GTP diphosphokinase Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. YjbM has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bsu:BSU11600 putative GTP pyrophosphokinase gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01318 BSBS38_01319 BSBS38_01319 ppnK ppnK 1257867 1258667 + NAD(+) kinase Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bsu:BSU11610 NAD+ kinase gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01319 BSBS38_01320 BSBS38_01320 BSBS38_01320 1258682 1259581 + 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B KEGG: bsr:I33_1296 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01320 BSBS38_01321 BSBS38_01321 apaH apaH 1259594 1260328 - Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) Asymmetrically hydrolyzes Ap4p to yield AMP and ATP%3B Belongs to the PrpE family%3B KEGG: bli:BL05112 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01321 BSBS38_01322 BSBS38_01322 BSBS38_01322 1260516 1262408 + Putative Na(+)/H(+) antiporter YjbQ Probable Na(+)/H(+) antiporter%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01322 BSBS38_01323 BSBS38_01323 tenA tenA 1262657 1263367 + Aminopyrimidine aminohydrolase Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds%2C a reaction that is part of a thiamine salvage pathway. Thus%2C catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP). To a lesser extent%2C is also able to catalyze the hydrolytic cleavage of thiamin%3B however%2C this thiaminase activity is unlikely to be physiologically relevant. Therefore%2C is involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment%2C rather than in thiamine degradation%3B Belongs to the TenA family%3B KEGG: bsu:BSU11650 thiaminase (transcriptional activator TenA) gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01323 BSBS38_01324 BSBS38_01324 tenI tenI 1263342 1263959 + Thiazole tautomerase Catalyzes the irreversible aromatization of 2-((2R%2C5Z)- 2-carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate (cThz*-P) to 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate (cThz-P)%2C a step in the biosynthesis of the thiazole phosphate moiety of thiamine. Cannot use cThz* as substrate%2C indicating that the phosphate group is essential. Has no thiamine phosphate synthase activity%2C despite a high sequence similarity with ThiE%3B Belongs to the thiazole tautomerase family%3B KEGG: bsu:BSU11660 thiazole tautomerase (transcriptional regulator TenI) gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01324 BSBS38_01325 BSBS38_01325 thiO thiO 1263943 1265052 + Glycine oxidase Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha- keto acids%2C ammonia/amine%2C and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine)%2C N-ethylglycine and glycine. Can also oxidize the herbicide glyphosate (N-phosphonomethylglycine). Displays lower activities on D-alanine%2C D-valine%2C D-proline and D- methionine. Does not act on L-amino acids and other D-amino acids. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate%3B Belongs to the DAO family%3B KEGG: bsu:BSU11670 glycine oxidase gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01325 BSBS38_01326 BSBS38_01326 BSBS38_01326 1265049 1265252 + Sulfur carrier protein ThiS Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate%3B Belongs to the sulfur carrier protein ThiS family gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01326 BSBS38_01327 BSBS38_01327 thiG thiG 1265255 1266019 + Thiazole synthase Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro%2C sulfur can be provided by H(2)S%3B Belongs to the ThiG family%3B KEGG: bsu:BSU11690 thiazole synthase gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01327 BSBS38_01328 BSBS38_01328 thiF thiF 1266016 1267026 + Sulfur carrier protein ThiS adenylyltransferase Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS%3B Belongs to the HesA/MoeB/ThiF family%3B KEGG: bsu:BSU11700 sulfur carrier protein ThiS adenylyltransferase gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01328 BSBS38_01329 BSBS38_01329 thiD thiD 1267045 1267860 + Hydroxymethylpyrimidine kinase Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP%2C and of HMP to HMP-P. Shows no activity with pyridoxal%2C pyridoxamine or pyridoxine%3B Belongs to the ThiD family%3B KEGG: bsu:BSU11710 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01329 BSBS38_01330 BSBS38_01330 fabI fabI 1267996 1268772 + Enoyl-[acyl-carrier-protein] reductase (NADH) Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily%3B KEGG: bsu:BSU11720 enoyl-(acyl-carrier protein) reductase I gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01330 BSBS38_01331 BSBS38_01331 BSBS38_01331 1268879 1269556 + Spore coat protein Has an important morphogenetic role. Involved in the assembly of at least five coat proteins%2C including CotB%2C CotG%2C CotS%2C CotSA and CotW. Required for appearance of a morphologically normal outer coat. To a large degree%2C CotO and CotH act at a late stage of coat assembly from within the outer coat to direct maturation of this structure gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01331 BSBS38_01332 BSBS38_01332 BSBS38_01332 1269650 1270096 - Spore coat protein To B. subtilis CotY gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01332 BSBS38_01333 BSBS38_01333 BSBS38_01333 1270224 1270712 - Spore coat protein Y To B. subtilis CotZ gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01333 BSBS38_01334 BSBS38_01334 BSBS38_01334 1270864 1271346 - Spore coat protein X gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01334 BSBS38_01335 BSBS38_01335 BSBS38_01335 1271431 1271751 - Spore coat protein gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01335 BSBS38_01336 BSBS38_01336 BSBS38_01336 1271791 1272177 - Spore coat protein gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01336 BSBS38_01337 BSBS38_01337 BSBS38_01337 1272337 1272693 + Sporulation protein YjcA Involved in sporulation%3B Belongs to the UPF0713 family gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01337 BSBS38_01338 BSBS38_01338 BSBS38_01338 1272974 1273180 + uncharacterized protein gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01338 BSBS38_01339 BSBS38_01339 BSBS38_01339 1273262 1273411 + UPF0752 sporulation protein YjcZ Belongs to the UPF0752 family gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01339 BSBS38_01340 BSBS38_01340 BSBS38_01340 1273544 1273798 + Sporulation-specific transcription factor SpoVIF Transcription factor involved in spore coat assembly and spore resistance. Regulates the transcription of at least cgeA%2C cotG and cotS gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01340 BSBS38_01341 BSBS38_01341 BSBS38_01341 1273872 1276151 - DNA helicase May be involved in the generation of recombinogenic substrates for the subsequent action of RecA. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsr:I33_1319 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01341 BSBS38_01342 BSBS38_01342 BSBS38_01342 1276268 1276522 + uncharacterized protein gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01342 BSBS38_01343 BSBS38_01343 BSBS38_01343 1276634 1276966 + hypothetical protein gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01343 BSBS38_01344 BSBS38_01344 BSBS38_01344 1276984 1277784 + putative transposase-like protein Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01344 BSBS38_01345 BSBS38_01345 BSBS38_01345 1277885 1278307 - putative N-acetyltransferase YjcF Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK1121 null%3B Transferring groups other than amino-acyl groups gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01345 BSBS38_01346 BSBS38_01346 BSBS38_01346 1278311 1278826 - Putative phosphoesterase Belongs to the 2H phosphoesterase superfamily. YjcG family gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01346 BSBS38_01347 BSBS38_01347 BSBS38_01347 1278863 1279585 - uncharacterized protein gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01347 BSBS38_01348 BSBS38_01348 metB metB 1279917 1281062 + Cystathionine gamma-synthase Catalyzes the formation of L-cystathionine from O- acetyl-L-homoserine and L-cysteine. Can not use O-succinyl-L- homoserine as substrate. Also exhibits O-acetylhomoserine thiolyase activity%2C catalyzing the synthesis of L-homocysteine from O-acetyl-L-homoserine and sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bsr:I33_1324 cystathionine gamma-synthase gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01348 BSBS38_01349 BSBS38_01349 metC metC 1281055 1282227 + Cystathionine beta-lyase Catalyzes the transformation of cystathionine into homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bsu:BSU11880 cystathionine beta-lyase gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01349 BSBS38_01350 BSBS38_01350 rimJ rimJ 1282260 1282805 - Ribosomal-protein-alanine N-acetyltransferase This enzyme acetylates the N-terminal alanine of ribosomal protein S5%3B Belongs to the acetyltransferase family. RimJ subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU11890 ribosomal-protein-alanine N-acetyltransferase gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01350 BSBS38_01351 BSBS38_01351 BSBS38_01351 1282875 1284065 - putative membrane protein YjcL gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01351 BSBS38_01352 BSBS38_01352 BSBS38_01352 1284238 1284310 + tRNA-Val tRNA gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01352 BSBS38_01353 BSBS38_01353 BSBS38_01353 1284792 1285151 - hypothetical protein gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01353 BSBS38_01354 BSBS38_01354 BSBS38_01354 1285215 1285511 - hypothetical protein gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01354 BSBS38_01355 BSBS38_01355 BSBS38_01355 1285533 1285892 - Phage-like element PBSX protein XkdA To B. subtilis YqaB gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01355 BSBS38_01356 BSBS38_01356 BSBS38_01356 1285867 1286031 - hypothetical protein gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01356 BSBS38_01357 BSBS38_01357 BSBS38_01357 1286103 1286450 - hypothetical protein gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01357 BSBS38_01358 BSBS38_01358 BSBS38_01358 1286463 1286984 - hypothetical protein gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01358 BSBS38_01359 BSBS38_01359 BSBS38_01359 1287347 1287718 - HTH-type transcriptional regulator Xre Repressor of PBSX. Binds to four sites close to its own gene. Necessary for the maintenance of the lysogenic state%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01359 BSBS38_01360 BSBS38_01360 BSBS38_01360 1287806 1288159 + hypothetical protein gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01360 BSBS38_01361 BSBS38_01361 BSBS38_01361 1288122 1288226 + hypothetical protein gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01361 BSBS38_01362 BSBS38_01362 BSBS38_01362 1288789 1288974 + hypothetical protein gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01362 BSBS38_01363 BSBS38_01363 BSBS38_01363 1289170 1290267 + hypothetical protein gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01363 BSBS38_01364 BSBS38_01364 BSBS38_01364 1290670 1291002 + hypothetical protein gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01364 BSBS38_01365 BSBS38_01365 BSBS38_01365 1291416 1292009 + Transposase for insertion sequence element IS904 Involved in the transposition of the insertion sequence. Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01365 BSBS38_01366 BSBS38_01366 tagE tagE 1291964 1293481 - Poly(glycerol-phosphate) alpha-glucosyltransferase Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bso:BSNT_02005 poly(glycerol-phosphate) alpha-glucosyltransferase gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01366 BSBS38_01367 BSBS38_01367 BSBS38_01367 1293547 1293762 - hypothetical protein gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01367 BSBS38_01368 BSBS38_01368 BSBS38_01368 1293896 1294159 + hypothetical protein gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01368 BSBS38_01369 BSBS38_01369 BSBS38_01369 1294315 1294587 + hypothetical protein gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01369 BSBS38_01370 BSBS38_01370 BSBS38_01370 1295111 1295296 + putative tape measure protein Serves as a base for tail tube protein polymerization and acts as a template for tail length determination. Exolysin involved in host peptidoglycan digestion necessary for viral DNA entry into the host cell (PubMed:14763988)%3B Belongs to the P2likevirus tape measure protein family gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01370 BSBS38_01371 BSBS38_01371 BSBS38_01371 1295609 1295944 + hypothetical protein gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01371 BSBS38_01372 BSBS38_01372 BSBS38_01372 1296223 1296390 + hypothetical protein gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01372 BSBS38_01373 BSBS38_01373 BSBS38_01373 1296377 1296946 + hypothetical protein gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01373 BSBS38_01374 BSBS38_01374 BSBS38_01374 1297110 1297337 - hypothetical protein gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01374 BSBS38_01375 BSBS38_01375 BSBS38_01375 1297424 1297525 - hypothetical protein gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01375 BSBS38_01376 BSBS38_01376 BSBS38_01376 1297546 1297698 - hypothetical protein gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01376 BSBS38_01377 BSBS38_01377 rapK rapK 1297695 1298810 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bso:BSNT_02017 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01377 BSBS38_01378 BSBS38_01378 BSBS38_01378 1299138 1300901 + Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01378 BSBS38_01379 BSBS38_01379 BSBS38_01379 1300917 1301384 + Antitoxin YobK Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the RNase activity of cognate toxin YobL%2C as well as its ability to inhibit growth upon expression in E. coli. Does not have antitoxin activity on other toxins with the LXG toxin domain gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01379 BSBS38_01380 BSBS38_01380 BSBS38_01380 1301515 1302753 + Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01380 BSBS38_01381 BSBS38_01381 BSBS38_01381 1302801 1303307 - Ribosomal-protein-alanine N-acetyltransferase Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: eao:BD94_2074 ribosomal-protein-alanine N-acetyltransferase gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01381 BSBS38_01382 BSBS38_01382 BSBS38_01382 1303526 1303921 - uncharacterized protein gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01382 BSBS38_01383 BSBS38_01383 ybaK ybaK 1304150 1304629 + Putative Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YjdI Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily%3B KEGG: bsu:BSU12060 Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase%3B Carboxylic ester hydrolases gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01383 BSBS38_01384 BSBS38_01384 BSBS38_01384 1304669 1304863 - uncharacterized protein gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01384 BSBS38_01385 BSBS38_01385 BSBS38_01385 1304995 1305324 - uncharacterized protein gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01385 BSBS38_01386 BSBS38_01386 cyoE cyoE 1305950 1306912 - Protoheme IX farnesyltransferase Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: bsu:BSU12080 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01386 BSBS38_01387 BSBS38_01387 BSBS38_01387 1307062 1307310 - Spore coat protein T gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01387 BSBS38_01388 BSBS38_01388 BSBS38_01388 1307567 1308967 + Peptidoglycan-N-acetylmuramic acid deacetylase PdaC Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in peptidoglycan%2C a modification that confers resistance to lysosyme. Is not able to deacetylate N- acetylglucosamine (GlcNAc) residues in peptidoglycan%2C but can deacylate chitin oligomers such as GlcNAc4 and GlcNAc5. Is essentially not active toward chitosan (partially deacetylated GlcNAc polymer) and has very low activity toward chitin (GlcNAc polymer). Does not deacetylate GlcNAc%3B Belongs to the polysaccharide deacetylase family%3B KEGG: baci:B1NLA3E_02370 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01388 BSBS38_01389 BSBS38_01389 BSBS38_01389 1309007 1309480 - uncharacterized protein gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01389 BSBS38_01390 BSBS38_01390 BSBS38_01390 1309605 1309772 - uncharacterized protein gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01390 BSBS38_01391 BSBS38_01391 BSBS38_01391 1309899 1310798 + uncharacterized protein gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01391 BSBS38_01392 BSBS38_01392 BSBS38_01392 1310808 1311299 - putative membrane protein YjgA gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01392 BSBS38_01393 BSBS38_01393 BSBS38_01393 1311307 1311882 - uncharacterized protein gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01393 BSBS38_01394 BSBS38_01394 fdoG fdoG 1312028 1314985 + Formate dehydrogenase In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU12160 formate dehydrogenase major subunit gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01394 BSBS38_01395 BSBS38_01395 BSBS38_01395 1314978 1315523 + uncharacterized protein gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01395 BSBS38_01396 BSBS38_01396 BSBS38_01396 1315735 1316379 + putative lipoprotein YjhA gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01396 BSBS38_01397 BSBS38_01397 nudF nudF 1316463 1317080 + ADP-ribose diphosphatase Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bcl:ABC0282 ADP-ribose pyrophosphatase gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01397 BSBS38_01398 BSBS38_01398 BSBS38_01398 1317111 1317389 - uncharacterized protein gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01398 BSBS38_01399 BSBS38_01399 BSBS38_01399 1317778 1318968 + Putative cytochrome P450 YjiB Belongs to the cytochrome P450 family%3B KEGG: bay:RBAM_012290 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01399 BSBS38_01400 BSBS38_01400 BSBS38_01400 1318991 1320169 + putative UDP-glucosyltransferase YjiC Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01400 BSBS38_01401 BSBS38_01401 BSBS38_01401 1320210 1320398 - uncharacterized protein gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01401 BSBS38_01402 BSBS38_01402 hemD hemD 1320572 1321384 + Uroporphyrinogen-III synthase KEGG: bsu:BSU12230 uroporphyrinogen-III synthase gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01402 BSBS38_01403 BSBS38_01403 BSBS38_01403 1321430 1322182 - UPF0014 membrane protein YjkA Belongs to the UPF0014 family gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01403 BSBS38_01404 BSBS38_01404 BSBS38_01404 1322182 1322934 - Putative ABC transporter ATP-binding protein YjkB Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01404 BSBS38_01405 BSBS38_01405 BSBS38_01405 1323054 1324028 - putative 42.1 kDa protein in intracellular alkaline protease 3'region gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01405 BSBS38_01406 BSBS38_01406 BSBS38_01406 1324160 1324657 + uncharacterized protein gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01406 BSBS38_01407 BSBS38_01407 BSBS38_01407 1325046 1325468 + uncharacterized protein gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01407 BSBS38_01408 BSBS38_01408 BSBS38_01408 1325508 1326686 + NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU12290 NADH dehydrogenase gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01408 BSBS38_01409 BSBS38_01409 uxaC uxaC 1326895 1328304 + Glucuronate isomerase Belongs to the uronate isomerase family%3B KEGG: sty:STY3308 glucuronate isomerase gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01409 BSBS38_01410 BSBS38_01410 BSBS38_01410 1328372 1329751 + putative symporter YjmB Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01410 BSBS38_01411 BSBS38_01411 allD allD 1329856 1330326 + Ureidoglycolate dehydrogenase (NAD(+)) Belongs to the LDH2/MDH2 oxidoreductase family%3B KEGG: bsl:A7A1_0241 ureidoglycolate dehydrogenase (NAD+) gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01411 BSBS38_01412 BSBS38_01412 BSBS38_01412 1330386 1330868 + Ureidoglycolate dehydrogenase (NAD(+)) Belongs to the LDH2/MDH2 oxidoreductase family%3B KEGG: bsr:I33_1387 ureidoglycolate dehydrogenase (NAD+) gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01412 BSBS38_01413 BSBS38_01413 rspB rspB 1330874 1331893 + L-gulonate 5-dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU12330 L-gulonate 5-dehydrogenase gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01413 BSBS38_01414 BSBS38_01414 uxuA uxuA 1331918 1332835 + Mannonate dehydratase Catalyzes the dehydration of D-mannonate%3B Belongs to the mannonate dehydratase family%3B KEGG: bsu:BSU12340 mannonate dehydratase%3B overlaps another CDS with the same product name gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01414 BSBS38_01415 BSBS38_01415 BSBS38_01415 1332792 1332998 + Mannonate dehydratase Catalyzes the dehydration of D-mannonate%3B Belongs to the mannonate dehydratase family%3B KEGG: bsu:BSU12340 mannonate dehydratase%3B overlaps another CDS with the same product name gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01415 BSBS38_01416 BSBS38_01416 BSBS38_01416 1332995 1333831 + putative oxidoreductase UxuB Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU12350 null%3B Oxidoreductases gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01416 BSBS38_01417 BSBS38_01417 BSBS38_01417 1333879 1335147 + Hexuronate transporter Aldohexuronate transport system. Belongs to the major facilitator superfamily. Phthalate permease family gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01417 BSBS38_01418 BSBS38_01418 BSBS38_01418 1335235 1336236 + Sucrose operon repressor Repressor for the csc operon. Binds D-fructose as an inducer (By similarity)%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01418 BSBS38_01419 BSBS38_01419 BSBS38_01419 1336311 1337753 + Tagaturonate reductase Belongs to the mannitol dehydrogenase family. UxaB subfamily%3B KEGG: bsu:BSU12380 tagaturonate reductase gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01419 BSBS38_01420 BSBS38_01420 uxaA uxaA 1337750 1339243 + Altronate dehydratase Catalyzes the dehydration of D-altronate%3B Belongs to the UxaA family%3B KEGG: gsn:YC6258_02780 altronate hydrolase gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01420 BSBS38_01421 BSBS38_01421 BSBS38_01421 1339282 1340046 - UPF0721 transmembrane protein YjnA Belongs to the UPF0721 family gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01421 BSBS38_01422 BSBS38_01422 BSBS38_01422 1340265 1340729 - uncharacterized protein Belongs to the DinB family gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01422 BSBS38_01423 BSBS38_01423 BSBS38_01423 1340878 1342149 + putative ATPase YjoB Shows ATPase activity%3B Belongs to the AAA ATPase family gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01423 BSBS38_01424 BSBS38_01424 rapA rapA 1342300 1343430 + Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU12430 response regulator aspartate phosphatase A (stage 0 sporulation protein L)%3B Acting on ester bonds gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01424 BSBS38_01425 BSBS38_01425 BSBS38_01425 1343420 1343554 + Phosphatase RapA inhibitor Inhibitor of the activity of phosphatase RapA. Belongs to the phr family gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01425 BSBS38_01426 BSBS38_01426 BSBS38_01426 1343619 1343831 - uncharacterized protein Belongs to the YciI family gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01426 BSBS38_01427 BSBS38_01427 BSBS38_01427 1343952 1344905 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bsu:BSU12460 N-acetylmuramoyl-L-alanine amidase gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01427 BSBS38_01428 BSBS38_01428 BSBS38_01428 1344945 1345322 - uncharacterized protein gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01428 BSBS38_01429 BSBS38_01429 BSBS38_01429 1345427 1346029 + UPF0714 protein YjqB Belongs to the UPF0714 family gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01429 BSBS38_01430 BSBS38_01430 BSBS38_01430 1346106 1346942 + uncharacterized protein Belongs to the manganese catalase family gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01430 BSBS38_01431 BSBS38_01431 BSBS38_01431 1346986 1347582 - Phage-like element PBSX protein XkdA To B. subtilis YqaB gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01431 BSBS38_01432 BSBS38_01432 BSBS38_01432 1347745 1348086 - Repressor LexA Repressor of PBSX. Binds to four sites close to its own gene. Necessary for the maintenance of the lysogenic state%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: ded:DHBDCA_p2309 repressor LexA gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01432 BSBS38_01433 BSBS38_01433 BSBS38_01433 1348265 1348444 + uncharacterized protein gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01433 BSBS38_01434 BSBS38_01434 BSBS38_01434 1348431 1349267 + Phage-like element PBSX protein XkdB To B. subtilis YqaL gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01434 BSBS38_01435 BSBS38_01435 BSBS38_01435 1349332 1349967 + Phage-like element PBSX protein XkdC May function as a transcriptional antiterminator. To B. subtilis YqaM gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01435 BSBS38_01436 BSBS38_01436 BSBS38_01436 1349967 1350134 + uncharacterized protein gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01436 BSBS38_01437 BSBS38_01437 BSBS38_01437 1350127 1350222 + hypothetical protein gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01437 BSBS38_01438 BSBS38_01438 BSBS38_01438 1350219 1350569 + Phage-like element PBSX protein XkdD gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01438 BSBS38_01439 BSBS38_01439 BSBS38_01439 1350566 1350772 + Phage-like element PBSX protein XtrA To B. subtilis YqaO gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01439 BSBS38_01440 BSBS38_01440 BSBS38_01440 1350888 1351397 + Positive control factor gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01440 BSBS38_01441 BSBS38_01441 BSBS38_01441 1351513 1352310 + PBSX phage terminase small subunit Functions as a terminase. To B. subtilis YqaS and B. subtilis phage SPP1 terminase small subunit gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01441 BSBS38_01442 BSBS38_01442 BSBS38_01442 1352307 1353608 + PBSX phage terminase large subunit Functions as a terminase. To B. subtilis YqaT and phage SPP1 terminase large subunit gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01442 BSBS38_01443 BSBS38_01443 BSBS38_01443 1353612 1355099 + Phage-like element PBSX protein XkdE Belongs to the phage portal family. PBSX subfamily gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01443 BSBS38_01444 BSBS38_01444 BSBS38_01444 1355119 1355946 + Site-specific DNA-methyltransferase (adenine-specific) To B. subtilis YqbD%3B KEGG: mxa:MXAN_1864 DNA adenine methylase gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01444 BSBS38_01445 BSBS38_01445 BSBS38_01445 1355972 1356907 + Phage-like element PBSX protein XkdG To B. subtilis YqbE gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01445 BSBS38_01446 BSBS38_01446 BSBS38_01446 1356929 1357312 + uncharacterized protein gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01446 BSBS38_01447 BSBS38_01447 BSBS38_01447 1357309 1357665 + Phage-like element PBSX protein XkdH To B. subtilis YqbH gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01447 BSBS38_01448 BSBS38_01448 BSBS38_01448 1357662 1358147 + Phage-like element PBSX protein XkdI To B. subtilis YqbI gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01448 BSBS38_01449 BSBS38_01449 BSBS38_01449 1358160 1358600 + Phage-like element PBSX protein XkdJ To B. subtilis YqbJ gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01449 BSBS38_01450 BSBS38_01450 BSBS38_01450 1358819 1360219 + Phage-like element PBSX protein XkdK Belongs to the myoviridae tail sheath protein family gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01450 BSBS38_01451 BSBS38_01451 BSBS38_01451 1360221 1360664 + Phage-like element PBSX protein XkdM To B. subtilis YqbM gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01451 BSBS38_01452 BSBS38_01452 BSBS38_01452 1360756 1361202 + Phage-like element PBSX protein XkdN To B. subtilis YqbN gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01452 BSBS38_01453 BSBS38_01453 BSBS38_01453 1361385 1366388 + Phage-like element PBSX protein XkdO To B. subtilis YqbO gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01453 BSBS38_01454 BSBS38_01454 BSBS38_01454 1366333 1367040 + Phage-like element PBSX protein XkdP Contains 1 LysM repeat gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01454 BSBS38_01455 BSBS38_01455 BSBS38_01455 1367056 1368033 + Phage-like element PBSX protein XkdQ To B. subtilis YqbQ gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01455 BSBS38_01456 BSBS38_01456 BSBS38_01456 1368033 1368299 + Phage-like element PBSX protein XkdR To B. subtilis YqbR gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01456 BSBS38_01457 BSBS38_01457 BSBS38_01457 1368357 1368782 + Phage-like element PBSX protein XkdS To B. subtilis YqbS gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01457 BSBS38_01458 BSBS38_01458 BSBS38_01458 1368775 1369821 + Phage-like element PBSX protein XkdT Belongs to the Mu gp47/PBSX XkdT family gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01458 BSBS38_01459 BSBS38_01459 BSBS38_01459 1369805 1370383 + Phage-like element PBSX protein XkdU To B. subtilis YqcA gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01459 BSBS38_01460 BSBS38_01460 BSBS38_01460 1370380 1370652 + uncharacterized protein gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01460 BSBS38_01461 BSBS38_01461 BSBS38_01461 1370655 1372718 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01461 BSBS38_01462 BSBS38_01462 BSBS38_01462 1372730 1373059 + Phage-like element PBSX protein XkdW To B. subtilis YqcC gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01462 BSBS38_01463 BSBS38_01463 BSBS38_01463 1373056 1373220 + Phage-like element PBSX protein XkdX To B. subtilis YqcE gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01463 BSBS38_01464 BSBS38_01464 BSBS38_01464 1373267 1374106 + Phage-like element PBSX protein XepA Not know%3B does not seem to be involved in host cell lysis. To B. subtilis YqxG/YqdC gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01464 BSBS38_01465 BSBS38_01465 BSBS38_01465 1374159 1374428 + Protein XhlA Associated with cell lysis upon induction of PbsX. To B. licheniformis xpaF1 and xpaL1 gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01465 BSBS38_01466 BSBS38_01466 BSBS38_01466 1374441 1374704 + Holin Involved in cell lysis upon induction of PbsX. Belongs to the SPP1 holin family gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01466 BSBS38_01467 BSBS38_01467 BSBS38_01467 1374717 1375610 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bsu:BSU12810 N-acetylmuramoyl-L-alanine amidase gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01467 BSBS38_01468 BSBS38_01468 BSBS38_01468 1375871 1376041 - Stage II sporulation protein SB Antitoxin component of a toxin-antitoxin (TA) module. Antitoxin that binds cognate toxin SpoIISA and neutralizes its toxic activit%3B unlike most antitoxins it does not seem to be highly labile upon expression in E. coli%3B Belongs to the SpoIISB antitoxin family gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01468 BSBS38_01469 BSBS38_01469 BSBS38_01469 1376041 1376787 - Stage II sporulation protein SA Toxic component of a toxin-antitoxin (TA) module. Its toxic activity is neutralized by cognate antitoxin SpoIISB. Expression in the absence of SpoIISB permits sporulation to stage II%2C when plasmolysis zones and holes in the peptidoglycan layer are observed%2C resulting in cell death. Lethal when synthesized during vegetative growth in the absence of SpoIISB. In E. coli both the membrane bound and soluble domain are required in cis for toxin activity%3B Belongs to the SpoIISA toxin family gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01469 BSBS38_01470 BSBS38_01470 BSBS38_01470 1376897 1377898 - putative low-affinity inorganic phosphate transporter Low-affinity inorganic phosphate transport%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family. Pit subfamily gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01470 BSBS38_01471 BSBS38_01471 BSBS38_01471 1377911 1378528 - UPF0111 protein YkaA Belongs to the UPF0111 family gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01471 BSBS38_01472 BSBS38_01472 BSBS38_01472 1378804 1379517 - Serine/threonine exchanger SteT Exhibits an obligate exchange activity for serine%2C threonine and aromatic amino acids%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2. A. 3. 8) family%3B overlaps another CDS with the same product name gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01472 BSBS38_01473 BSBS38_01473 BSBS38_01473 1379504 1380112 - Serine/threonine exchanger SteT Exhibits an obligate exchange activity for serine%2C threonine and aromatic amino acids%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2. A. 3. 8) family%3B overlaps another CDS with the same product name gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01473 BSBS38_01474 BSBS38_01474 BSBS38_01474 1380501 1381451 + Putative ring-cleaving dioxygenase MhqA Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01474 BSBS38_01475 BSBS38_01475 arnT arnT 1381668 1382453 + Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase Belongs to the glycosyltransferase 39 family%3B KEGG: amo:Anamo_1886 4-amino-4-deoxy-L-arabinose transferase gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01475 BSBS38_01476 BSBS38_01476 BSBS38_01476 1382589 1383818 + Putative mannosyltransferase YkcB Belongs to the glycosyltransferase 39 family gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01476 BSBS38_01477 BSBS38_01477 BSBS38_01477 1383830 1384801 + Dolichyl-phosphate beta-D-mannosyltransferase Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: bsu:BSU12890 dolichol-phosphate mannosyltransferase gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01477 BSBS38_01478 BSBS38_01478 BSBS38_01478 1384967 1385143 - hypothetical protein gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01478 BSBS38_01479 BSBS38_01479 degP degP 1385301 1386653 - Peptidase Do Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bsr:I33_1452 serine protease Do gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01479 BSBS38_01480 BSBS38_01480 proC proC 1386819 1387637 + Pyrroline-5-carboxylate reductase Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU12910 pyrroline-5-carboxylate reductase gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01480 BSBS38_01481 BSBS38_01481 BSBS38_01481 1387767 1388591 + D-aminopeptidase Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates%2C the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear. Belongs to the peptidase M55 family%3B KEGG: bsu:BSU12920 D-amino peptidase%3B Aminopeptidases gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01481 BSBS38_01482 BSBS38_01482 BSBS38_01482 1388620 1389534 + Dipeptide transport system permease protein DppB Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01482 BSBS38_01483 BSBS38_01483 BSBS38_01483 1389531 1390502 + Dipeptide transport system permease protein DppC Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01483 BSBS38_01484 BSBS38_01484 BSBS38_01484 1390507 1391514 + Dipeptide transport ATP-binding protein DppD Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system. Expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01484 BSBS38_01485 BSBS38_01485 BSBS38_01485 1391535 1393166 + Dipeptide-binding protein DppE Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the bacterial solute-binding protein 5 family gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01485 BSBS38_01486 BSBS38_01486 BSBS38_01486 1393166 1393306 + hypothetical protein gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01486 BSBS38_01487 BSBS38_01487 ldcA ldcA 1393272 1394213 + Muramoyltetrapeptide carboxypeptidase May be involved in the degradation of peptidoglycan by catalyzing the cleavage of the terminal D-alanine residue from cytoplasmic murein peptides%3B Belongs to the peptidase S66 family%3B KEGG: bsu:BSU12970 muramoyltetrapeptide carboxypeptidase gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01487 BSBS38_01488 BSBS38_01488 catB catB 1394210 1395289 + Muconate cycloisomerase Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L- Glu and has probably a role in the metabolism of the murein peptide%2C of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of the other Ala-X dipeptides L-Ala-L-Asp%2C L-Ala-L-Leu%2C L-Ala-L-Met%2C and L-Ala- L-Ser. Is not able to epimerize other L-Ala-X dipeptides. Is also active with L-Ser-L-Glu and%2C oddly%2C L-Pro-L-Glu%2C but not with L- Glu-L-Glu%2C L-Lys-L-Glu%2C L-Lys-L-Ala%2C or D-Ala-D-Ala%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family%3B KEGG: mph:MLP_40790 muconate cycloisomerase gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01488 BSBS38_01489 BSBS38_01489 BSBS38_01489 1395306 1396196 + Gamma-D-glutamyl-L-lysine endopeptidase Specifically hydrolyzes gamma-D-glutamyl-L-lysine bonds in murein peptides%2C releasing L-Ala-D-Glu%3B Belongs to the peptidase C40 family%3B KEGG: baci:B1NLA3E_10835 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01489 BSBS38_01490 BSBS38_01490 BSBS38_01490 1396209 1397198 + Putative oligopeptide transport ATP-binding protein YkfD Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01490 BSBS38_01491 BSBS38_01491 BSBS38_01491 1397241 1398290 - 6-phosphogluconolactonase Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate%3B Belongs to the cycloisomerase 2 family%3B KEGG: bsu:BSU13010 6-phosphogluconolactonase gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01491 BSBS38_01492 BSBS38_01492 arcA arcA 1398380 1398853 - Arginine deiminase Belongs to the DDAH family%3B KEGG: nca:Noca_2424 arginine deiminase gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01492 BSBS38_01493 BSBS38_01493 BSBS38_01493 1399357 1399917 + Acyl-CoA hydrolase Belongs to the acyl coenzyme A hydrolase family%3B Contains 1 HotDog ACOT-type domain%3B KEGG: ban:BA_2053 acyl-CoA hydrolase gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01493 BSBS38_01494 BSBS38_01494 yhb1 yhb1 1400155 1401354 + Nitric oxide dioxygenase Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the bacterium from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress (By similarity)%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: pseo:OM33_21110 nitric oxide dioxygenase gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01494 BSBS38_01495 BSBS38_01495 BSBS38_01495 1401431 1401655 - uncharacterized protein gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01495 BSBS38_01496 BSBS38_01496 BSBS38_01496 1401804 1402535 + UPF0702 transmembrane protein YkjA Belongs to the UPF0702 family gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01496 BSBS38_01497 BSBS38_01497 BSBS38_01497 1402627 1403154 + uncharacterized protein gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01497 BSBS38_01498 BSBS38_01498 BSBS38_01498 1403144 1403662 + Ribosomal-protein-alanine N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: pih:UB51_25750 ribosomal-protein-alanine N-acetyltransferase gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01498 BSBS38_01499 BSBS38_01499 BSBS38_01499 1403884 1404222 + Multidrug resistance protein YkkC Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01499 BSBS38_01500 BSBS38_01500 BSBS38_01500 1404222 1404539 + Multidrug resistance protein YkkD Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01500 BSBS38_01501 BSBS38_01501 purU purU 1404610 1405512 + Formyltetrahydrofolate deformylase Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)%3B Belongs to the PurU family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU13110 formyltetrahydrofolate deformylase gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01501 BSBS38_01502 BSBS38_01502 proB proB 1405863 1406960 + Glutamate 5-kinase Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: rma:Rmag_0413 glutamate 5-kinase gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01502 BSBS38_01503 BSBS38_01503 proA proA 1406972 1408219 + Glutamate-5-semialdehyde dehydrogenase Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: bsu:BSU13130 glutamate-5-semialdehyde dehydrogenase gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01503 BSBS38_01504 BSBS38_01504 BSBS38_01504 1408345 1408770 + Organic hydroperoxide resistance protein OhrA Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01504 BSBS38_01505 BSBS38_01505 BSBS38_01505 1408801 1409244 - Organic hydroperoxide resistance transcriptional regulator Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements%3B Contains 1 HTH marR-type DNA-binding domain gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01505 BSBS38_01506 BSBS38_01506 BSBS38_01506 1409386 1409796 + Organic hydroperoxide resistance protein OhrB Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01506 BSBS38_01507 BSBS38_01507 guaD guaD 1410044 1410514 - Guanine deaminase Catalyzes the hydrolytic deamination of guanine%2C producing xanthine and ammonia%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bsu:BSU13170 guanine deaminase gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01507 BSBS38_01508 BSBS38_01508 metE metE 1410689 1412977 - 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation%3B Belongs to the vitamin-B12 independent methionine synthase family%3B KEGG: bsu:BSU13180 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01508 BSBS38_01509 BSBS38_01509 BSBS38_01509 1413393 1414352 - Major intracellular serine protease Major intracellular protease produced by Bacillus subtilis. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU13190 major intracellular serine protease%3B Serine endopeptidases gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01509 BSBS38_01510 BSBS38_01510 BSBS38_01510 1414575 1415408 + RsbT co-antagonist protein RsbRB One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01510 BSBS38_01511 BSBS38_01511 BSBS38_01511 1415439 1416203 - Putative HMP/thiamine permease protein YkoC Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the CbiQ family gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01511 BSBS38_01512 BSBS38_01512 BSBS38_01512 1416178 1417821 - Putative HMP/thiamine import ATP-binding protein YkoD Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Responsible for energy coupling to the transport system (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains%3B KEGG: bsu:BSU13220 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01512 BSBS38_01513 BSBS38_01513 BSBS38_01513 1417808 1418407 - Putative HMP/thiamine permease protein YkoE Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable) gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01513 BSBS38_01514 BSBS38_01514 BSBS38_01514 1418409 1419011 - Putative HMP/thiamine-binding protein YkoF Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Binds thiamine via its HMP moiety gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01514 BSBS38_01515 BSBS38_01515 BSBS38_01515 1419322 1420008 + putative transcriptional regulatory protein YkoG Probable member of the two-component regulatory system YkoH/YkoG%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01515 BSBS38_01516 BSBS38_01516 BSBS38_01516 1420012 1420533 + Sensor histidine kinase YkoH Probable member of the two-component regulatory system YkoH/YkoG. Potentially phosphorylates YkoG%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU13260 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01516 BSBS38_01517 BSBS38_01517 BSBS38_01517 1420566 1421375 + Sensor histidine kinase YkoH Probable member of the two-component regulatory system YkoH/YkoG. Potentially phosphorylates YkoG%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU13260 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01517 BSBS38_01518 BSBS38_01518 BSBS38_01518 1421372 1422052 + putative membrane protein YkoI gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01518 BSBS38_01519 BSBS38_01519 BSBS38_01519 1422144 1422656 + uncharacterized protein gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01519 BSBS38_01520 BSBS38_01520 BSBS38_01520 1422739 1422876 + uncharacterized protein gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01520 BSBS38_01521 BSBS38_01521 BSBS38_01521 1423241 1423363 + hypothetical protein gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01521 BSBS38_01522 BSBS38_01522 BSBS38_01522 1423381 1424736 + Magnesium transporter MgtE Acts as a magnesium transporter%3B Belongs to the SLC41A transporter family%3B Contains 2 CBS domains gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01522 BSBS38_01523 BSBS38_01523 BSBS38_01523 1424779 1425111 - HTH-type transcriptional regulator TnrA Regulator of transcription that activates or represses many genes during nitrogen-limited growt%3B among others%2C it activates nrgAB%2C nasABCDE%2C gabP%2C and represses glnRA%3B Contains 1 HTH merR-type DNA-binding domain gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01523 BSBS38_01524 BSBS38_01524 BSBS38_01524 1425305 1425460 + uncharacterized protein gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01524 BSBS38_01525 BSBS38_01525 BSBS38_01525 1425548 1425730 + Stress response protein YkoL gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01525 BSBS38_01526 BSBS38_01526 BSBS38_01526 1425863 1426327 + putative HTH-type transcriptional regulator YkoM Contains 1 HTH marR-type DNA-binding domain gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01526 BSBS38_01527 BSBS38_01527 ugtP ugtP 1426328 1426849 - 1%2C2-diacylglycerol 3-glucosyltransferase Belongs to the glycosyltransferase 28 family%3B KEGG: bmet:BMMGA3_10315 processive 1%2C2-diacylglycerol beta-glucosyltransferase gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01527 BSBS38_01528 BSBS38_01528 BSBS38_01528 1426973 1427464 - 1%2C2-diacylglycerol 3-glucosyltransferase Belongs to the glycosyltransferase 28 family%3B KEGG: gym:GYMC10_5150 processive 1%2C2-diacylglycerol beta-glucosyltransferase gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01528 BSBS38_01529 BSBS38_01529 BSBS38_01529 1427556 1428107 + uncharacterized protein gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01529 BSBS38_01530 BSBS38_01530 BSBS38_01530 1428135 1428947 - putative metallophosphoesterase YkoQ Belongs to the metallophosphoesterase superfamily gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01530 BSBS38_01531 BSBS38_01531 BSBS38_01531 1429140 1430834 + putative membrane protein YkoS gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01531 BSBS38_01532 BSBS38_01532 BSBS38_01532 1430847 1431860 + Dolichyl-phosphate beta-D-mannosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: fco:FCOL_06185 dolichol-phosphate mannosyltransferase gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01532 BSBS38_01533 BSBS38_01533 ligD ligD 1431886 1433721 - DNA ligase (ATP) Probably involved in DNA repair during spore germination%3B The preference of the polymerase domain for rNTPs over dNTPs may be advantageous in dormant cells%2C where the dNTP pool may be limiting%3B In the N-terminal sectio%3B belongs to the LigD polymerase family%3B In the C-terminal sectio%3B belongs to the ATP- dependent DNA ligase family gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01533 BSBS38_01534 BSBS38_01534 BSBS38_01534 1433725 1434609 - Non-like proteinous end joining protein Ku Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD (By similarity). Probably involved in DNA repair during spore germination%3B Belongs to the prokaryotic Ku family%3B Contains 1 Ku domain gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01534 BSBS38_01535 BSBS38_01535 BSBS38_01535 1434697 1437099 - Signaling protein YkoW Probable signaling protein whose physiological role is not yet known. Contains 1 EAL domain%3B Contains 1 GGDEF domain%3B Contains 1 MHYT domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: she:Shewmr4_0791 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01535 BSBS38_01536 BSBS38_01536 BSBS38_01536 1437310 1437945 + putative membrane protein YkoX Belongs to the DedA family gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01536 BSBS38_01537 BSBS38_01537 BSBS38_01537 1438022 1438996 + putative membrane protein YkoY Belongs to the TerC family gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01537 BSBS38_01538 BSBS38_01538 BSBS38_01538 1439260 1440015 + RNA polymerase sigma factor SigI Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor plays a role in survival at low temperatures and could be involved in heat shock stress response%2C positively regulating the expression of genes such as bcrC and mreBH during this stress%3B Belongs to the sigma-70 factor family gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01538 BSBS38_01539 BSBS38_01539 BSBS38_01539 1440012 1441157 + Anti-sigma-I factor RsgI Anti-sigma factor for SigI. Negatively regulates SigI activity through direct interaction gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01539 BSBS38_01540 BSBS38_01540 BSBS38_01540 1441168 1441362 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01540 BSBS38_01541 BSBS38_01541 BSBS38_01541 1441493 1442194 - uncharacterized protein gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01541 BSBS38_01542 BSBS38_01542 htpX htpX 1442366 1443262 + Protease HtpX like protein Belongs to the peptidase M48B family%3B KEGG: bsu:BSU13490 heat shock protein HtpX%3B Metalloendopeptidases gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01542 BSBS38_01543 BSBS38_01543 BSBS38_01543 1443436 1444785 + Ktr system potassium uptake protein Integral membrane subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the TrkH potassium transport family. Ktr (TC 2. A. 38. 4) subfamily gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01543 BSBS38_01544 BSBS38_01544 BSBS38_01544 1444930 1445085 + uncharacterized protein gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01544 BSBS38_01545 BSBS38_01545 BSBS38_01545 1445088 1445264 + uncharacterized protein gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01545 BSBS38_01546 BSBS38_01546 BSBS38_01546 1445319 1446341 - Putative membrane-bound acyltransferase YkrP Belongs to the acyltransferase 3 family gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01546 BSBS38_01547 BSBS38_01547 kinE kinE 1446594 1448810 + Histidine kinase Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F%3B Contains 1 histidine kinase domain%3B Contains 4 PAS (PER-ARNT-SIM) domains%3B KEGG: bsu:BSU13530 two-component system%2C sporulation sensor kinase E gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01547 BSBS38_01548 BSBS38_01548 mgmT mgmT 1448807 1449304 + Methylated-DNA--[protein]-cysteine S-methyltransferase Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated%3B Belongs to the MGMT family%3B KEGG: bsu:BSU13540 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01548 BSBS38_01549 BSBS38_01549 BSBS38_01549 1449394 1449519 + hypothetical protein gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01549 BSBS38_01550 BSBS38_01550 mtnA mtnA 1449552 1450613 - S-methyl-5-thioribose-1-phosphate isomerase Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)%3B Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily%3B KEGG: bsu:BSU13550 methylthioribose-1-phosphate isomerase gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01550 BSBS38_01551 BSBS38_01551 mtnK mtnK 1450621 1451814 - S-methyl-5-thioribose kinase Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate%3B Belongs to the methylthioribose kinase family%3B KEGG: bsu:BSU13560 5-methylthioribose kinase gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01551 BSBS38_01552 BSBS38_01552 BSBS38_01552 1452147 1452926 - Hydrolase MtnU May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway%3B Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01552 BSBS38_01553 BSBS38_01553 mtnE mtnE 1453021 1454217 + Transaminase MtnE Catalyzes the formation of methionine from 2-keto-4- methylthiobutyrate (KMTB)%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. MtnE subfamily%3B KEGG: bsu:BSU13580 aminotransferase%3B Transaminases gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01553 BSBS38_01554 BSBS38_01554 mtnW mtnW 1454441 1455658 + 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase Catalyzes the enolization of 2%2C3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)%3B Belongs to the RuBisCO large chain family. Type IV subfamily%3B KEGG: bsu:BSU13590 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01554 BSBS38_01555 BSBS38_01555 mtnX mtnX 1455655 1456362 + 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1%2C2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)%3B Belongs to the HAD-like hydrolase superfamily. MtnX family%3B KEGG: bsu:BSU13600 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01555 BSBS38_01556 BSBS38_01556 mtnB mtnB 1456320 1456949 + Methylthioribulose 1-phosphate dehydratase Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2%2C3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)%3B Belongs to the aldolase class II family. MtnB subfamily%3B KEGG: bsu:BSU13610 methylthioribulose-1-phosphate dehydratase gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01556 BSBS38_01557 BSBS38_01557 mtnD mtnD 1456964 1457500 + Acireductone dioxygenase (Ni(2+)-requiring) Catalyzes 2 different reactions between oxygene and the acireductone 1%2C2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB)%2C the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate%2C carbon monoxide and formate%2C and does not lie on the methionine recycle pathway%3B Belongs to the acireductone dioxygenase (ARD) family%3B KEGG: bsu:BSU13620 1%2C2-dihydroxy-3-keto-5-methylthiopentene dioxygenase gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01557 BSBS38_01558 BSBS38_01558 BSBS38_01558 1457541 1457861 - putative membrane protein YkvA gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01558 BSBS38_01559 BSBS38_01559 BSBS38_01559 1458064 1458321 + Aspartyl-phosphate phosphatase Spo0E Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01559 BSBS38_01560 BSBS38_01560 BSBS38_01560 1458407 1458754 + uncharacterized protein gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01560 BSBS38_01561 BSBS38_01561 kinD kinD 1458864 1460366 - Histidine kinase Phosphorylates the sporulation-regulatory protein spo0F and%2C to a minor extent%2C is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU13660 two-component system%2C sporulation sensor kinase D gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01561 BSBS38_01562 BSBS38_01562 BSBS38_01562 1460577 1461014 + HTH-type transcriptional regulator MhqR Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01562 BSBS38_01563 BSBS38_01563 BSBS38_01563 1461054 1461836 - Motility protein MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque- generating machinery to the cell wall (By similarity)%3B Belongs to the MotB family%3B Contains 1 OmpA-like domain%3B overlaps another CDS with the same product name gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01563 BSBS38_01564 BSBS38_01564 BSBS38_01564 1461811 1462620 - Motility protein MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity)%3B Belongs to the MotA family%3B overlaps another CDS with the same product name gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01564 BSBS38_01565 BSBS38_01565 BSBS38_01565 1463005 1465104 - ATP-dependent Clp protease ATP-binding subunit ClpE ATPase essential both for efficient CtsR-dependent gene derepression during heat stress and for rerepression. Together with ClpP%2C degrades the global regulator CtsR after heat shock. Is also involved in disaggregation of heat-denatured proteins. Has thus a role in overall protein quality control in response to heat stress%3B Belongs to the ClpA/ClpB family. ClpE subfamily%3B Contains 1 UVR domain gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01565 BSBS38_01566 BSBS38_01566 BSBS38_01566 1465472 1466515 + putative membrane protein YkvI gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01566 BSBS38_01567 BSBS38_01567 queC queC 1466828 1467487 + 7-cyano-7-deazaguanine synthase Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))%3B Belongs to the QueC family%3B KEGG: dal:Dalk_4152 7-cyano-7-deazaguanine synthase gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01567 BSBS38_01568 BSBS38_01568 queD queD 1467489 1467929 + 6-pyruvoyltetrahydropterin synthase Catalyzes the conversion of 7%2C8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin (CPH4) and acetaldehyde%3B Belongs to the PTPS family. QueD subfamily%3B KEGG: bsu:BSU13730 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01568 BSBS38_01569 BSBS38_01569 queE queE 1467922 1468653 + 7-carboxy-7-deazaguanine synthase Catalyzes the conversion of 6-carboxy-5%2C6%2C7%2C8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG)%3B Belongs to the radical SAM superfamily. 7-carboxy-7- deazaguanine synthase family%3B KEGG: bsu:BSU13740 7-carboxy-7-deazaguanine synthase gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01569 BSBS38_01570 BSBS38_01570 queF queF 1468671 1469168 + PreQ(1) synthase Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)%3B Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily%3B KEGG: bsu:BSU13750 7-cyano-7-deazaguanine reductase gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01570 BSBS38_01571 BSBS38_01571 BSBS38_01571 1469653 1470009 - putative HTH-type transcriptional regulator YkvN Contains 1 HTH hxlR-type DNA-binding domain gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01571 BSBS38_01572 BSBS38_01572 budC budC 1470178 1470924 + putative oxidoreductase YkvO Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: esa:ESA_01866 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01572 BSBS38_01573 BSBS38_01573 BSBS38_01573 1472204 1472428 - hypothetical protein gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01573 BSBS38_01574 BSBS38_01574 BSBS38_01574 1472499 1472810 - hypothetical protein gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01574 BSBS38_01575 BSBS38_01575 BSBS38_01575 1472824 1474257 - hypothetical protein gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01575 BSBS38_01576 BSBS38_01576 BSBS38_01576 1474315 1474632 + hypothetical protein gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01576 BSBS38_01577 BSBS38_01577 BSBS38_01577 1475464 1475715 - hypothetical protein gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01577 BSBS38_01578 BSBS38_01578 BSBS38_01578 1476103 1477008 + hypothetical protein gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01578 BSBS38_01579 BSBS38_01579 BSBS38_01579 1477001 1477324 + hypothetical protein gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01579 BSBS38_01580 BSBS38_01580 BSBS38_01580 1477542 1478549 + RNA-directed DNA polymerase Participates in the synthesis of a msDNA (a branched RNA linked by a 2'%2C5'-phosphodiester linkage to a single-stranded DNA) of unknown function. The retron transcript serves as primer and template to the reaction%2C and codes for the RT. Contains 1 reverse transcriptase domain%3B KEGG: fnu:FN0161 RNA-directed DNA polymerase gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01580 BSBS38_01581 BSBS38_01581 BSBS38_01581 1479026 1479484 + Putative glycosylase YkvQ Belongs to the glycosyl hydrolase 18 family gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01581 BSBS38_01582 BSBS38_01582 BSBS38_01582 1480215 1480505 + uncharacterized protein gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01582 BSBS38_01583 BSBS38_01583 BSBS38_01583 1480627 1480812 - uncharacterized protein gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01583 BSBS38_01584 BSBS38_01584 BSBS38_01584 1480975 1481172 + uncharacterized protein gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01584 BSBS38_01585 BSBS38_01585 BSBS38_01585 1481471 1482097 + N-acetylmuramoyl-L-alanine amidase KEGG: bsu:BSU13820 N-acetylmuramoyl-L-alanine amidase gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01585 BSBS38_01586 BSBS38_01586 BSBS38_01586 1482215 1483552 + Sporulation protein YkvU gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01586 BSBS38_01587 BSBS38_01587 BSBS38_01587 1483603 1484100 + Sporulation thiol-disulfide oxidoreductase Thiol-disulfide oxidoreductase with a reductive function%2C involved in spore cortex synthesis. It could be involved either in breaking disulfide bonds in cortex components or in proteins that are important for cortex synthesis%2C or in thiol/disulfide bond interchange%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01587 BSBS38_01588 BSBS38_01588 zntA zntA 1484336 1486249 + Cadmium-exporting ATPase Couples the hydrolysis of ATP with the transport of zinc into the cell. Plays an important role in protecting cells against oxidative stress. ZosA-mediated zinc transport is required for post-transcriptional control of comK and competence development%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B KEGG: bsu:BSU13850 Cd2+/Zn2+-exporting ATPase gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01588 BSBS38_01589 BSBS38_01589 pepQ pepQ 1486657 1487751 + Xaa-Pro dipeptidase Belongs to the peptidase M24B family%3B KEGG: bsu:BSU13860 Xaa-Pro dipeptidase gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01589 BSBS38_01590 BSBS38_01590 BSBS38_01590 1488213 1488998 + putative HTH-type transcriptional regulator YkvZ Contains 1 HTH lacI-type DNA-binding domain gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01590 BSBS38_01591 BSBS38_01591 BSBS38_01591 1488949 1489119 + hypothetical protein gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01591 BSBS38_01592 BSBS38_01592 BSBS38_01592 1489082 1489927 + PtsGHI operon antiterminator Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of GlcT directly binds to the RNA antiterminator (RAT) sequence and prevents transcriptional termination. GlcT binding requires two identical and nearly symmetrical triple base pairings in the RAT sequence%3B Belongs to the transcriptional antiterminator BglG family. GlcT subfamily%3B Contains 2 PRD domains gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01592 BSBS38_01593 BSBS38_01593 BSBS38_01593 1490156 1492255 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU13890 PTS system%2C D-glucosamine-specific IIA component gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01593 BSBS38_01594 BSBS38_01594 BSBS38_01594 1492353 1492619 + Phosphocarrier protein General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). P-Ser-HPr interacts with the catabolite control protein A (CcpA)%2C forming a complex that binds to DNA at the catabolite response elements cre%2C operator sites preceding a large number of catabolite-regulated genes. Thus%2C P-Ser-HPr is a corepressor in carbon catabolite repression (CCR)%2C a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion%2C in which it probably interacts with several non-PTS permeases and inhibits their transport activity. Belongs to the HPr family%3B Contains 1 HPr domain gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01594 BSBS38_01595 BSBS38_01595 ptsI ptsI 1492619 1494331 + Phosphoenolpyruvate--protein phosphotransferase General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU13910 phosphotransferase system%2C enzyme I%2C PtsI gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01595 BSBS38_01596 BSBS38_01596 BSBS38_01596 1494422 1494661 + Transcriptional regulator SplA gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01596 BSBS38_01597 BSBS38_01597 splB splB 1494739 1495767 + Spore photoproduct lyase Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5%2C6- dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines%3B Belongs to the radical SAM superfamily. SPL family%3B KEGG: bsu:BSU13930 spore photoproduct lyase gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01597 BSBS38_01598 BSBS38_01598 BSBS38_01598 1495760 1496461 - putative N-acetyltransferase YkwB Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01598 BSBS38_01599 BSBS38_01599 BSBS38_01599 1496596 1498563 + Methyl-accepting chemotaxis protein McpC Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpC is required for taxis to cysteine%2C proline%2C threonine%2C glycine%2C serine%2C lysine%2C valine and arginine and for aspartate%2C glutamine%2C histidine and glutamate. Primarily mediates response to positive stimulus of PTS carbohydrates. Greatly influences the duration or magnitude of the response to negative PTS carbohydrate stimulus%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01599 BSBS38_01600 BSBS38_01600 BSBS38_01600 1498701 1499567 + 3-hydroxyisobutyrate dehydrogenase Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: bsr:I33_1574 3-hydroxyisobutyrate dehydrogenase gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01600 BSBS38_01601 BSBS38_01601 BSBS38_01601 1499608 1500846 - Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01601 BSBS38_01602 BSBS38_01602 BSBS38_01602 1500983 1501756 - uncharacterized protein Contains 1 SCP domain gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01602 BSBS38_01603 BSBS38_01603 BSBS38_01603 1502093 1504213 + Peptidoglycan glycosyltransferase Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP2a in determining the rod shape of the cell during vegetative growth and spore outgrowth%3B Belongs to the transpeptidase family%3B KEGG: bcz:BCZK2802 peptidoglycan glycosyltransferase gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01603 BSBS38_01604 BSBS38_01604 kinA kinA 1504377 1506209 + Histidine kinase Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP. Contains 1 histidine kinase domain%3B Contains 2 PAC (PAS-associated C-terminal) domains%3B Contains 3 PAS (PER-ARNT-SIM) domains%3B KEGG: bsu:BSU13990 two-component system%2C sporulation sensor kinase A gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01604 BSBS38_01605 BSBS38_01605 BSBS38_01605 1506471 1507676 - hypothetical protein gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01605 BSBS38_01606 BSBS38_01606 patA patA 1507786 1508967 - Putative N-acetyl-LL-diaminopimelate aminotransferase May catalyze the conversion of L-2-acetamido-6- oxopimelate to N-acetyl-LL-2%2C6-diaminopimelate%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU14000 aminotransferase%3B Transaminases gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01606 BSBS38_01607 BSBS38_01607 BSBS38_01607 1509169 1509330 - uncharacterized protein gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01607 BSBS38_01608 BSBS38_01608 BSBS38_01608 1509534 1510445 + Chemotaxis protein CheV Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis. Moreover%2C CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B. subtilis chemotaxis%3B Contains 1 cheW-like domain%3B Contains 1 response regulatory domain gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01608 BSBS38_01609 BSBS38_01609 BSBS38_01609 1510489 1510953 - uncharacterized protein gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01609 BSBS38_01610 BSBS38_01610 BSBS38_01610 1511079 1512371 - dTMP kinase Belongs to the major facilitator superfamily%3B KEGG: abai:IMCC26256_11234 dTMP kinase gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01610 BSBS38_01611 BSBS38_01611 BSBS38_01611 1512447 1512950 - Putative L%2CD-transpeptidase YkuD Probable enzyme that may play an important role in cell wall biology%3B Belongs to the YkuD family%3B Contains 1 LysM repeat gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01611 BSBS38_01612 BSBS38_01612 BSBS38_01612 1512998 1513858 - putative metallophosphoesterase YkuE Belongs to the metallophosphoesterase superfamily gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01612 BSBS38_01613 BSBS38_01613 badH badH 1514001 1514765 + putative 2%2C4-dienoyl-CoA reductase Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2%2C4-dienoyl-CoA to yield trans-3- enoyl-CoA (By similarity)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2%2C4-dienoyl-CoA reductase subfamily%3B KEGG: papi:SG18_02580 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01613 BSBS38_01614 BSBS38_01614 BSBS38_01614 1514829 1516052 + Protein-glutamate O-methyltransferase Contains 1 EAL domain%3B KEGG: mah:MEALZ_1025 two-component system%2C chemotaxis family%2C CheB/CheR fusion protein gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01614 BSBS38_01615 BSBS38_01615 BSBS38_01615 1516670 1516909 + uncharacterized protein gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01615 BSBS38_01616 BSBS38_01616 BSBS38_01616 1517020 1517538 + uncharacterized protein gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01616 BSBS38_01617 BSBS38_01617 BSBS38_01617 1517678 1517869 + uncharacterized protein gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01617 BSBS38_01618 BSBS38_01618 BSBS38_01618 1518007 1518450 + CBS domain-containing protein YkuL Contains 1 CBS domain gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01618 BSBS38_01619 BSBS38_01619 BSBS38_01619 1518597 1519478 + putative HTH-type transcriptional regulator YkuM Contains 1 HTH lysR-type DNA-binding domain gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01619 BSBS38_01620 BSBS38_01620 BSBS38_01620 1519590 1520066 + NAD(P)H dehydrogenase (quinone) Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain%3B KEGG: gbm:Gbem_3607 NAD(P)H dehydrogenase (quinone) gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01620 BSBS38_01621 BSBS38_01621 BSBS38_01621 1520056 1520949 + uncharacterized protein gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01621 BSBS38_01622 BSBS38_01622 BSBS38_01622 1520965 1521420 + putative flavodoxin-2 Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01622 BSBS38_01623 BSBS38_01623 dapH dapH 1521525 1522235 + Tetrahydrodipicolinate N-acetyltransferase Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate%3B Belongs to the transferase hexapeptide repeat family. DapH subfamily%3B KEGG: bsu:BSU14180 tetrahydrodipicolinate N-acetyltransferase gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01623 BSBS38_01624 BSBS38_01624 BSBS38_01624 1522305 1523429 + N-acetyldiaminopimelate deacetylase Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate%3B Belongs to the peptidase M20A family. N- acetyldiaminopimelate deacetylase subfamily%3B KEGG: bsr:I33_1597 N-acetyldiaminopimelate deacetylase gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01624 BSBS38_01625 BSBS38_01625 BSBS38_01625 1523491 1523736 + UPF0180 protein Belongs to the UPF0180 family gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01625 BSBS38_01626 BSBS38_01626 BSBS38_01626 1523773 1524576 - putative MscS family protein YkuT May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01626 BSBS38_01627 BSBS38_01627 prdX prdX 1524813 1525355 + Peroxiredoxin Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain%3B KEGG: bfr:BF2266 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01627 BSBS38_01628 BSBS38_01628 BSBS38_01628 1525425 1525871 + Thiol-disulfide oxidoreductase YkuV Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Contains 1 thioredoxin domain gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01628 BSBS38_01629 BSBS38_01629 BSBS38_01629 1526337 1526912 + Repressor rok gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01629 BSBS38_01630 BSBS38_01630 BSBS38_01630 1526980 1527780 - putative transposase-like protein Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01630 BSBS38_01631 BSBS38_01631 BSBS38_01631 1527798 1528130 - hypothetical protein gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01631 BSBS38_01632 BSBS38_01632 BSBS38_01632 1528243 1529208 - Sporulation protein cse15 gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01632 BSBS38_01633 BSBS38_01633 mobA mobA 1529345 1529944 + Molybdenum cofactor guanylyltransferase Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor%3B Belongs to the MobA family%3B KEGG: bsu:BSU14260 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01633 BSBS38_01634 BSBS38_01634 BSBS38_01634 1529995 1531014 + Sulfur carrier protein ThiS adenylyltransferase Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD%3B Belongs to the HesA/MoeB/ThiF family%3B KEGG: eru:Erum8480 sulfur carrier protein ThiS adenylyltransferase gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01634 BSBS38_01635 BSBS38_01635 moeA moeA 1531032 1532324 + Molybdopterin molybdotransferase Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP%3B Belongs to the MoeA family%3B KEGG: bsu:BSU14280 molybdopterin molybdotransferase gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01635 BSBS38_01636 BSBS38_01636 BSBS38_01636 1532285 1532806 + putative molybdopterin-guanine dinucleotide biosynthesis adapter protein GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor%2C and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity)%3B Belongs to the MobB family gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01636 BSBS38_01637 BSBS38_01637 moaE moaE 1532806 1533279 + Molybdopterin synthase Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity)%3B Belongs to the MoaE family%3B KEGG: bsu:BSU14300 molybdopterin synthase catalytic subunit gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01637 BSBS38_01638 BSBS38_01638 BSBS38_01638 1533272 1533505 + Molybdopterin synthase sulfur carrier subunit Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin%3B Belongs to the MoaD family gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01638 BSBS38_01639 BSBS38_01639 BSBS38_01639 1533729 1535486 + putative ABC transporter ATP-binding protein YknU Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01639 BSBS38_01640 BSBS38_01640 BSBS38_01640 1535498 1537312 + putative ABC transporter ATP-binding protein YknV Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01640 BSBS38_01641 BSBS38_01641 BSBS38_01641 1537422 1538117 + Membrane protein YknW Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein). Has a role in the assembly of the YknXYZ complex gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01641 BSBS38_01642 BSBS38_01642 BSBS38_01642 1538122 1539255 + Putative efflux system component YknX Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01642 BSBS38_01643 BSBS38_01643 macB macB 1539256 1539948 + Macrolide export ATP-binding/permease protein MacB Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain%3B KEGG: efe:EFER_1027 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01643 BSBS38_01644 BSBS38_01644 BSBS38_01644 1539945 1541138 + putative ABC transporter permease YknZ Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the ABC-4 integral membrane protein family gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01644 BSBS38_01645 BSBS38_01645 BSBS38_01645 1541418 1542173 + putative HTH-type transcriptional regulator FruR Contains 1 HTH deoR-type DNA-binding domain gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01645 BSBS38_01646 BSBS38_01646 pfkB pfkB 1542170 1543081 + 6-phosphofructokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: sty:STY3436 6-phosphofructokinase 2 gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01646 BSBS38_01647 BSBS38_01647 fruB fruB 1543096 1545003 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: ron:TE10_11530 PTS system%2C fructose-specific IIA component gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01647 BSBS38_01648 BSBS38_01648 BSBS38_01648 1545148 1545729 + Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bsu:BSU14410 signal peptidase I gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01648 BSBS38_01649 BSBS38_01649 BSBS38_01649 1545763 1546032 - uncharacterized protein gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01649 BSBS38_01650 BSBS38_01650 BSBS38_01650 1546213 1547835 + Arabinose import ATP-binding protein AraG Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Arabinose importer (TC 3. A. 1. 2. 2) family%3B Contains 2 ABC transporter domains gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01650 BSBS38_01651 BSBS38_01651 panE panE 1547892 1548803 + 2-dehydropantoate 2-reductase Belongs to the ketopantoate reductase family%3B KEGG: vap:Vapar_2967 2-dehydropantoate 2-reductase gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01651 BSBS38_01652 BSBS38_01652 BSBS38_01652 1548837 1550069 - Aminopeptidase AmpS Metal-dependent exopeptidase%3B Belongs to the peptidase M29 family%3B KEGG: bsu:BSU14450 aminopeptidase%3B Aminopeptidases gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01652 BSBS38_01653 BSBS38_01653 BSBS38_01653 1550178 1550312 - uncharacterized protein gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01653 BSBS38_01654 BSBS38_01654 BSBS38_01654 1550413 1551432 - Protein MreBH Belongs to the FtsA/MreB family gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01654 BSBS38_01655 BSBS38_01655 BSBS38_01655 1551704 1551982 + Putative transition state regulator Abh Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and SpoVT gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01655 BSBS38_01656 BSBS38_01656 kinC kinC 1552172 1553458 + Histidine kinase Phosphorylates the sporulation-regulatory protein spo0A. Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU14490 two-component system%2C sporulation sensor kinase C gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01656 BSBS38_01657 BSBS38_01657 BSBS38_01657 1553474 1554307 + Putative gamma-glutamylcyclotransferase YkqA Putative gamma-glutamylcyclotransferase%3B Belongs to the gamma-glutamylcyclotransferase family gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01657 BSBS38_01658 BSBS38_01658 BSBS38_01658 1554370 1555035 + Ktr system potassium uptake protein Catalytic subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01658 BSBS38_01659 BSBS38_01659 BSBS38_01659 1555190 1556923 + Adenine deaminase Belongs to the adenine deaminase family%3B KEGG: bsu:BSU14520 adenine deaminase gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01659 BSBS38_01660 BSBS38_01660 BSBS38_01660 1556957 1558624 - Ribonuclease J1 An RNase that has endonuclease and 5'-3' exonuclease activity%2C playing a role in both rRNA and mRNA stability and degradation. Endonuclease activity can cleave within 4 nucleotides of the 5'-end of a triphosphorylated RNA. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Preferentially cleaves ssRNA%2C possibly in AU-rich regions. The 5'- exonuclease activity acts on 5'-hydroxyl and 5'-monophosphate but not 5'-triphosphate end%3B it can digest through stem-loop structures if they are not too stable. Required for maturation of 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal subunits. Plays a role in the secondary pathway of 23S rRNA 5' end maturation. Probably also participates in processing of pre-scRNA (the precursor of the signal recognition particle RNA)%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bsu:BSU14530 ribonuclease J%3B Acting on ester bonds gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01660 BSBS38_01661 BSBS38_01661 BSBS38_01661 1558630 1558839 - UPF0356 protein Belongs to the UPF0356 family gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01661 BSBS38_01662 BSBS38_01662 BSBS38_01662 1559177 1559998 + Putative phosphatase YkrA Belongs to the HAD-like hydrolase superfamily. Cof family gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01662 BSBS38_01663 BSBS38_01663 BSBS38_01663 1560035 1560589 - Peptide deformylase Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Belongs to the polypeptide deformylase family%3B KEGG: bsu:BSU14560 peptide deformylase gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01663 BSBS38_01664 BSBS38_01664 BSBS38_01664 1560699 1560857 - UPF0752 membrane protein YkzV Belongs to the UPF0752 family gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01664 BSBS38_01665 BSBS38_01665 BSBS38_01665 1561071 1561331 + putative lipoprotein YkyA overlaps another CDS with the same product name gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01665 BSBS38_01666 BSBS38_01666 BSBS38_01666 1561297 1561743 + putative lipoprotein YkyA overlaps another CDS with the same product name gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01666 BSBS38_01667 BSBS38_01667 BSBS38_01667 1562167 1563282 + Pyruvate dehydrogenase (acetyl-transferring) KEGG: bsu:BSU14580 pyruvate dehydrogenase E1 component alpha subunit gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01667 BSBS38_01668 BSBS38_01668 BSBS38_01668 1563286 1564263 + Pyruvate dehydrogenase (acetyl-transferring) KEGG: rhd:R2APBS1_0530 pyruvate dehydrogenase E1 component beta subunit gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01668 BSBS38_01669 BSBS38_01669 dlaT dlaT 1564378 1565706 + Dihydrolipoyllysine-residue acetyltransferase The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1)%2C dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The B. subtilis PDH complex possesses also branched-chain 2-oxoacid dehydrogenase (BCDH) activity. Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: rbu:PG1C_10405 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01669 BSBS38_01670 BSBS38_01670 BSBS38_01670 1565711 1567123 + Dihydrolipoyl dehydrogenase Catalyzes the oxidation of dihydrolipoamide to lipoamide. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: bsu:BSU14610 dihydrolipoamide dehydrogenase gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01670 BSBS38_01671 BSBS38_01671 BSBS38_01671 1567168 1567542 - Pal-related lipoprotein gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01671 BSBS38_01672 BSBS38_01672 speA speA 1568120 1569592 - Arginine decarboxylase Catalyzes the formation of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: bsu:BSU14630 arginine decarboxylase gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01672 BSBS38_01673 BSBS38_01673 BSBS38_01673 1569777 1570043 + UPF0223 protein Belongs to the UPF0223 family gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01673 BSBS38_01674 BSBS38_01674 BSBS38_01674 1570076 1570714 - UPF0637 protein YktB Belongs to the UPF0637 family gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01674 BSBS38_01675 BSBS38_01675 BSBS38_01675 1570897 1571142 + uncharacterized protein gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01675 BSBS38_01676 BSBS38_01676 impA impA 1571282 1572079 + Inositol-phosphate phosphatase Belongs to the inositol monophosphatase family%3B KEGG: bsu:BSU14670 myo-inositol-1(or 4)-monophosphatase gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01676 BSBS38_01677 BSBS38_01677 BSBS38_01677 1572066 1572533 + uncharacterized protein Contains 1 N-acetyltransferase domain gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01677 BSBS38_01678 BSBS38_01678 BSBS38_01678 1572611 1573525 - Putative S-adenosyl-L-methionine-dependent methyltransferase YktD May be involved in polyketide synthesis. Belongs to the UPF0677 family gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01678 BSBS38_01679 BSBS38_01679 nprE nprE 1573876 1575441 - Bacillolysin Extracellular zinc metalloprotease. Belongs to the peptidase M4 family%3B KEGG: bsu:BSU14700 bacillolysin gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01679 BSBS38_01680 BSBS38_01680 BSBS38_01680 1575735 1577666 + uncharacterized protein overlaps another CDS with the same product name gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01680 BSBS38_01681 BSBS38_01681 BSBS38_01681 1577656 1577925 + uncharacterized protein overlaps another CDS with the same product name gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01681 BSBS38_01682 BSBS38_01682 BSBS38_01682 1577925 1578191 + RNA polymerase sigma factor YlaC Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor contributes to oxidative stress resistance%3B Belongs to the sigma-70 factor family. ECF subfamily%3B overlaps another CDS with the same product name gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01682 BSBS38_01683 BSBS38_01683 BSBS38_01683 1578134 1578445 + RNA polymerase sigma factor YlaC Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor contributes to oxidative stress resistance%3B Belongs to the sigma-70 factor family. ECF subfamily%3B overlaps another CDS with the same product name gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01683 BSBS38_01684 BSBS38_01684 BSBS38_01684 1578442 1578735 + Anti-sigma-YlaC factor YlaD Anti-sigma factor for YlaC%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01684 BSBS38_01685 BSBS38_01685 BSBS38_01685 1578775 1579386 - uncharacterized protein gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01685 BSBS38_01686 BSBS38_01686 BSBS38_01686 1579659 1579847 - uncharacterized protein gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01686 BSBS38_01687 BSBS38_01687 BSBS38_01687 1579960 1581798 + GTP-binding protein TypA/BipA like protein Not know%3B probably interacts with the ribosomes in a GTP dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TypA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01687 BSBS38_01688 BSBS38_01688 BSBS38_01688 1581855 1582172 + putative membrane protein YlaH gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01688 BSBS38_01689 BSBS38_01689 BSBS38_01689 1582228 1582434 - uncharacterized protein gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01689 BSBS38_01690 BSBS38_01690 BSBS38_01690 1582520 1583149 - putative lipoprotein YlaJ gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01690 BSBS38_01691 BSBS38_01691 BSBS38_01691 1583304 1584632 + uncharacterized protein In the C-terminal sectio%3B belongs to the PhoH family%3B Contains 1 PINc domain gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01691 BSBS38_01692 BSBS38_01692 BSBS38_01692 1584635 1585120 - uncharacterized protein gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01692 BSBS38_01693 BSBS38_01693 BSBS38_01693 1585223 1586152 + Glutaminase Belongs to the glutaminase family%3B KEGG: bsr:I33_1665 glutaminase gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01693 BSBS38_01694 BSBS38_01694 BSBS38_01694 1586250 1586531 + UPF0358 protein Belongs to the UPF0358 family gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01694 BSBS38_01695 BSBS38_01695 BSBS38_01695 1586737 1587948 + Putative lipid II flippase FtsW Essential cell division protein (Probable). Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity)%3B Belongs to the SEDS family. FtsW subfamily gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01695 BSBS38_01696 BSBS38_01696 BSBS38_01696 1588023 1591469 + Pyruvate carboxylase Catalyzes a 2-step reaction%2C involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second%2C leading to oxaloacetate production. Fulfills an anaplerotic function in B. subtilis as it is necessary for growth on glucose%2C but is not required for sporulation%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B Contains 1 biotinyl-binding domain%3B Contains 1 carboxyltransferase domain%3B KEGG: bsu:BSU14860 pyruvate carboxylase gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01696 BSBS38_01697 BSBS38_01697 BSBS38_01697 1591883 1592803 - Heme A synthase Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group%3B Belongs to the COX15/CtaA family. Type 1 subfamily gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01697 BSBS38_01698 BSBS38_01698 BSBS38_01698 1593158 1594075 + Protoheme IX farnesyltransferase Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: bsu:BSU14880 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01698 BSBS38_01699 BSBS38_01699 coxB coxB 1594315 1595385 + Cytochrome-c oxidase Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). Belongs to the cytochrome c oxidase subunit 2 family%3B Contains 1 cytochrome c domain%3B KEGG: bsu:BSU14890 cytochrome c oxidase subunit II gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01699 BSBS38_01700 BSBS38_01700 coxA coxA 1595418 1597286 + Cytochrome-c oxidase Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bsu:BSU14900 cytochrome c oxidase subunit I%3B overlaps another CDS with the same product name gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01700 BSBS38_01701 BSBS38_01701 coxC coxC 1597286 1597909 + Cytochrome-c oxidase Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bsu:BSU14910 cytochrome c oxidase subunit III%3B overlaps another CDS with the same product name gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01701 BSBS38_01702 BSBS38_01702 coxD coxD 1597912 1598244 + Cytochrome-c oxidase Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bsu:BSU14920 cytochrome c oxidase subunit IV gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01702 BSBS38_01703 BSBS38_01703 BSBS38_01703 1598272 1599165 + Protein CtaG gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01703 BSBS38_01704 BSBS38_01704 BSBS38_01704 1599197 1599559 - uncharacterized protein gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01704 BSBS38_01705 BSBS38_01705 BSBS38_01705 1599699 1600145 + uncharacterized protein Contains 2 CBS domains gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01705 BSBS38_01706 BSBS38_01706 BSBS38_01706 1600184 1601269 + putative membrane protein YlbC Contains 1 SCP domain gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01706 BSBS38_01707 BSBS38_01707 BSBS38_01707 1601500 1601898 + uncharacterized protein gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01707 BSBS38_01708 BSBS38_01708 BSBS38_01708 1601914 1602153 + uncharacterized protein gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01708 BSBS38_01709 BSBS38_01709 BSBS38_01709 1602269 1602718 + Regulatory protein YlbF Regulates sporulation prior to stage II. Positively controls the competence regulator ComK at a post-transcriptional level. May modulate the translation%2C stability or activity of ComS. May work together with YmcA to regulate community development gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01709 BSBS38_01710 BSBS38_01710 BSBS38_01710 1602794 1603045 + UPF0298 protein Belongs to the UPF0298 family gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01710 BSBS38_01711 BSBS38_01711 rsmD rsmD 1603368 1603922 + 16S rRNA (guanine(966)-N(2))-methyltransferase May catalyze the S-adenosyl-L-methionine-dependent methylation of a specific base in rRNA%3B Belongs to the methyltransferase superfamily. RsmD family%3B KEGG: vsp:VS_3023 16S rRNA (guanine966-N2)-methyltransferase gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01711 BSBS38_01712 BSBS38_01712 coaD coaD 1603927 1604412 + Pantetheine-phosphate adenylyltransferase Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine%2C yielding dephospho-CoA (dPCoA) and pyrophosphate%3B Belongs to the bacterial CoaD family%3B KEGG: bsu:BSU15020 pantetheine-phosphate adenylyltransferase gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01712 BSBS38_01713 BSBS38_01713 BSBS38_01713 1604423 1605649 - Sporulation integral membrane protein YlbJ Required for spore cortex formation gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01713 BSBS38_01714 BSBS38_01714 BSBS38_01714 1605830 1606612 + putative NTE family protein YlbK Belongs to the NTE family%3B Contains 1 patatin domain gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01714 BSBS38_01715 BSBS38_01715 BSBS38_01715 1606614 1607639 + uncharacterized protein Contains 1 PDZ (DHR) domain gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01715 BSBS38_01716 BSBS38_01716 BSBS38_01716 1607656 1608903 - UPF0348 protein Belongs to the UPF0348 family gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01716 BSBS38_01717 BSBS38_01717 BSBS38_01717 1608900 1609085 - uncharacterized protein gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01717 BSBS38_01718 BSBS38_01718 BSBS38_01718 1609113 1609631 + uncharacterized protein gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01718 BSBS38_01719 BSBS38_01719 BSBS38_01719 1609653 1609832 + 50S ribosomal protein L32-2 Belongs to the ribosomal protein L32P family gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01719 BSBS38_01720 BSBS38_01720 BSBS38_01720 1609978 1610559 + uncharacterized protein Contains 1 HTH myb-type DNA-binding domain gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01720 BSBS38_01721 BSBS38_01721 BSBS38_01721 1610616 1611098 - putative N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3680 null%3B Transferring groups other than amino-acyl groups gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01721 BSBS38_01722 BSBS38_01722 BSBS38_01722 1611258 1612154 + 2-dehydropantoate 2-reductase Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid%3B Belongs to the ketopantoate reductase family%3B KEGG: bsu:BSU15110 2-dehydropantoate 2-reductase gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01722 BSBS38_01723 BSBS38_01723 BSBS38_01723 1612225 1613844 + Putative cysteine ligase BshC Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway%2C the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH%3B Belongs to the BshC family gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01723 BSBS38_01724 BSBS38_01724 BSBS38_01724 1613955 1614401 + Transcriptional regulator MraZ Belongs to the MraZ family%3B Contains 2 SpoVT-AbrB domains gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01724 BSBS38_01725 BSBS38_01725 mraW mraW 1614471 1615406 + 16S rRNA (cytosine(1402)-N(4))-methyltransferase Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmH family%3B KEGG: ppno:DA70_18955 16S rRNA (cytosine1402-N4)-methyltransferase gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01725 BSBS38_01726 BSBS38_01726 BSBS38_01726 1615446 1615799 + Cell division protein FtsL Essential cell division protein that may play a structural role. Probably involved in the regulation of the timing of cell division. Also required for sporulation%3B Belongs to the FtsL family gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01726 BSBS38_01727 BSBS38_01727 BSBS38_01727 1615805 1617946 + Penicillin-binding protein 2B Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. PBP-2B is required for vegetative cell division and sporulation septation. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family%3B Contains 2 PASTA domains gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01727 BSBS38_01728 BSBS38_01728 BSBS38_01728 1618063 1620003 + Stage V sporulation protein D Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex%2C which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell. Belongs to the transpeptidase family%3B Contains 1 PASTA domain gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01728 BSBS38_01729 BSBS38_01729 murE murE 1620179 1621663 + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan%3B Belongs to the MurCDEF family. MurE subfamily%3B KEGG: bsu:BSU15180 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01729 BSBS38_01730 BSBS38_01730 mraY mraY 1621775 1622749 + Phospho-N-acetylmuramoyl-pentapeptide-transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan%3B Belongs to the glycosyltransferase 4 family. MraY subfamily%3B KEGG: bsu:BSU15190 phospho-N-acetylmuramoyl-pentapeptide-transferase gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01730 BSBS38_01731 BSBS38_01731 murD murD 1622750 1624105 + UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)%3B Belongs to the MurCDEF family%3B KEGG: bsu:BSU15200 UDP-N-acetylmuramoylalanine--D-glutamate ligase gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01731 BSBS38_01732 BSBS38_01732 BSBS38_01732 1624241 1625266 + Stage V sporulation protein May play an essential role not only during sporulation%2C but also during vegetative growth. Belongs to the SEDS family. SpoVE subfamily gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01732 BSBS38_01733 BSBS38_01733 murG murG 1625387 1626478 + Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)%3B Belongs to the glycosyltransferase 28 family. MurG subfamily%3B KEGG: bsu:BSU15220 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01733 BSBS38_01734 BSBS38_01734 murB murB 1626510 1627421 + UDP-N-acetylmuramate dehydrogenase Cell wall formation%3B Belongs to the MurB family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bsu:BSU15230 UDP-N-acetylmuramate dehydrogenase gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01734 BSBS38_01735 BSBS38_01735 BSBS38_01735 1627551 1628342 + Cell division protein DivIB Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex. Plays an essential role in division at high temperatures%2C maybe by protecting FtsL from degradation or by promoting formation of the FtsL-DivIC complex. May modulate the transpeptidase activity of PBP-2B. Also required for efficient sporulation at all temperatures. Could be directly involved in the engulfment process or be required to form a sporulation septum competent for engulfment. Influences the Spo0J/Soj system of chromosome segregation%3B Belongs to the FtsQ/DivIB family. DivIB subfamily%3B Contains 1 POTRA domain gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01735 BSBS38_01736 BSBS38_01736 BSBS38_01736 1628339 1629034 + UPF0749 protein YlxW May be involved in cell division and sporulation%3B Belongs to the UPF0749 family gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01736 BSBS38_01737 BSBS38_01737 BSBS38_01737 1629096 1629764 + UPF0749 protein YlxX Belongs to the UPF0749 family gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01737 BSBS38_01738 BSBS38_01738 BSBS38_01738 1629782 1630147 + Small basic protein Belongs to the sbp family gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01738 BSBS38_01739 BSBS38_01739 BSBS38_01739 1630321 1631643 + Cell division protein FtsA Cell division protein that is required for the assembly of the Z ring (PubMed:16159787). May serve as a membrane anchor for the Z ring (By similarity). Binds and hydrolyzes ATP (PubMed:11298280). Also involved in sporulation (Probable)%3B Belongs to the FtsA/MreB family gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01739 BSBS38_01740 BSBS38_01740 BSBS38_01740 1631679 1632827 + Cell division protein FtsZ Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity%3B Belongs to the FtsZ family gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01740 BSBS38_01741 BSBS38_01741 BSBS38_01741 1633130 1637431 + Bacillopeptidase Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU15300 bacillopeptidase F%3B Serine endopeptidases gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01741 BSBS38_01742 BSBS38_01742 BSBS38_01742 1637373 1637672 + hypothetical protein gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01742 BSBS38_01743 BSBS38_01743 BSBS38_01743 1637626 1638555 + Sporulation sigma-E factor-processing peptidase Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR (By similarity)%3B Belongs to the peptidase U4 family%3B KEGG: bsu:BSU15310 stage II sporulation protein GA (sporulation sigma-E factor processing peptidase)%3B Aspartic endopeptidases gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01743 BSBS38_01744 BSBS38_01744 BSBS38_01744 1638618 1639337 + RNA polymerase sigma-E factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01744 BSBS38_01745 BSBS38_01745 BSBS38_01745 1639477 1640259 + RNA polymerase sigma-G factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. Belongs to the sigma-70 factor family gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01745 BSBS38_01746 BSBS38_01746 BSBS38_01746 1640407 1641201 + putative ABC transporter ATP-binding protein YlmA Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01746 BSBS38_01747 BSBS38_01747 argE argE 1641403 1642683 + Acetylornithine deacetylase Catalyzes the deformylation of the formylaminopyrimidine N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP) to give the corresponding aminopyrimidine%3B Belongs to the peptidase M20A family%3B KEGG: bsu:BSU15350 acetylornithine deacetylase gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01747 BSBS38_01748 BSBS38_01748 BSBS38_01748 1642766 1643011 + uncharacterized protein Belongs to the YlmC/YmxH family gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01748 BSBS38_01749 BSBS38_01749 BSBS38_01749 1643173 1644009 + Laccase domain protein YlmD Belongs to the LACC1 family gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01749 BSBS38_01750 BSBS38_01750 BSBS38_01750 1644016 1644708 + UPF0001 protein YlmE Belongs to the UPF0001 family gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01750 BSBS38_01751 BSBS38_01751 BSBS38_01751 1644705 1645160 + Cell division protein SepF Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation%2C perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA%3B Belongs to the SepF family gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01751 BSBS38_01752 BSBS38_01752 BSBS38_01752 1645167 1645439 + putative membrane protein YlmG Belongs to the YggT family gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01752 BSBS38_01753 BSBS38_01753 BSBS38_01753 1645500 1646273 + Putative RNA-binding protein YlmH Contains 1 S4 RNA-binding domain gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01753 BSBS38_01754 BSBS38_01754 BSBS38_01754 1646367 1646861 + Septum site-determining protein DivIVA May act as a pilot protein%2C directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation%3B Belongs to the DivIVA family gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01754 BSBS38_01755 BSBS38_01755 iarS iarS 1647202 1649967 + Isoleucine--tRNA ligase Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine%2C to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily%3B KEGG: hhe:HH1190 isoleucyl-tRNA synthetase gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01755 BSBS38_01756 BSBS38_01756 BSBS38_01756 1650111 1650485 + uncharacterized protein Contains 1 dksA C4-type zinc finger gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01756 BSBS38_01757 BSBS38_01757 lspA lspA 1650588 1651052 + Signal peptidase II This protein specifically catalyzes the removal of signal peptides from prolipoproteins%3B Belongs to the peptidase A8 family%3B KEGG: bsu:BSU15450 signal peptidase II gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01757 BSBS38_01758 BSBS38_01758 BSBS38_01758 1651054 1651965 + 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bsu:BSU15460 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01758 BSBS38_01759 BSBS38_01759 pyrR pyrR 1652148 1652693 + Uracil phosphoribosyltransferase Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator%2C leading to a reduced expression of downstream genes%3B Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily%3B KEGG: bsu:BSU15470 pyrimidine operon attenuation protein / uracil phosphoribosyltransferase gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01759 BSBS38_01760 BSBS38_01760 BSBS38_01760 1652837 1654171 + Uracil permease Transport of uracil in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01760 BSBS38_01761 BSBS38_01761 pyrB pyrB 1654316 1655230 + Aspartate carbamoyltransferase Belongs to the ATCase/OTCase family%3B KEGG: bsu:BSU15490 aspartate carbamoyltransferase catalytic subunit gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01761 BSBS38_01762 BSBS38_01762 ura4 ura4 1655214 1656500 + Dihydroorotase Belongs to the DHOase family. Type 2 subfamily%3B KEGG: bsu:BSU15500 dihydroorotase gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01762 BSBS38_01763 BSBS38_01763 BSBS38_01763 1656497 1657591 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU15510 carbamoyl-phosphate synthase small subunit%3B overlaps another CDS with the same product name gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01763 BSBS38_01764 BSBS38_01764 BSBS38_01764 1657576 1660791 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: ssz:SCc_117 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01764 BSBS38_01765 BSBS38_01765 BSBS38_01765 1660788 1661558 + Dihydroorotate dehydrogenase B (NAD(+))%2C electron transfer subunit Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+)%3B Belongs to the PyrK family%3B Contains 1 FAD-binding FR-type domain gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01765 BSBS38_01766 BSBS38_01766 BSBS38_01766 1661558 1662493 + Dihydroorotate dehydrogenase (NAD(+)) Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor. Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily%3B KEGG: bsu:BSU15540 dihydroorotate dehydrogenase (NAD+) catalytic subunit gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01766 BSBS38_01767 BSBS38_01767 pyrF pyrF 1662462 1663181 + Orotidine-5'-phosphate decarboxylase Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP). Belongs to the OMP decarboxylase family. Type 1 subfamily%3B KEGG: bsu:BSU15550 orotidine-5'-phosphate decarboxylase gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01767 BSBS38_01768 BSBS38_01768 pyrE pyrE 1663178 1663810 + Orotate phosphoribosyltransferase Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate%2C leading to the formation of orotidine monophosphate (OMP)%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily%3B KEGG: bsu:BSU15560 orotate phosphoribosyltransferase gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01768 BSBS38_01769 BSBS38_01769 BSBS38_01769 1664222 1664923 + Phosphoadenylyl-sulfate reductase (thioredoxin) Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: bsu:BSU15570 phosphoadenosine phosphosulfate reductase gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01769 BSBS38_01770 BSBS38_01770 BSBS38_01770 1664935 1665999 + Sulfate permease CysP Involved in the import of sulfate%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01770 BSBS38_01771 BSBS38_01771 BSBS38_01771 1666048 1667196 + Sulfate adenylyltransferase Belongs to the sulfate adenylyltransferase family%3B KEGG: bsu:BSU15590 sulfate adenylyltransferase gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01771 BSBS38_01772 BSBS38_01772 BSBS38_01772 1667209 1667802 + Adenylyl-sulfate kinase Catalyzes the synthesis of activated sulfate%3B Belongs to the APS kinase family%3B KEGG: sun:SUN_1719 adenylylsulfate kinase gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01772 BSBS38_01773 BSBS38_01773 cobA cobA 1667901 1668674 + Uroporphyrinogen-III C-methyltransferase Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-%3B their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin. Belongs to the precorrin methyltransferase family%3B KEGG: shl:Shal_3534 uroporphyrin-III C-methyltransferase gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01773 BSBS38_01774 BSBS38_01774 sirB sirB 1668677 1669462 + Sirohydrochlorin ferrochelatase Chelates iron to the siroheme precursor%3B Belongs to the CbiX family. SirB subfamily%3B KEGG: bsu:BSU15620 sirohydrochlorin ferrochelatase gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01774 BSBS38_01775 BSBS38_01775 met8 met8 1669443 1669931 + Precorrin-2 dehydrogenase Catalyzes the dehydrogenation of precorrin-2 to form sirohydrochlorin which is used as a precursor in both siroheme biosynthesis and in the anaerobic branch of adenosylcobalamin biosynthesis%3B Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family%3B KEGG: bsu:BSU15630 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01775 BSBS38_01776 BSBS38_01776 BSBS38_01776 1669971 1671683 - uncharacterized protein Belongs to the NEMF family gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01776 BSBS38_01777 BSBS38_01777 BSBS38_01777 1671805 1674477 + Calcium-transporting ATPase This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IIA subfamily%3B KEGG: bsu:BSU15650 Ca2+-transporting ATPase gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01777 BSBS38_01778 BSBS38_01778 BSBS38_01778 1674560 1675435 + UPF0701 protein YloC Belongs to the UPF0701 family gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01778 BSBS38_01779 BSBS38_01779 BSBS38_01779 1675512 1675781 + UPF0296 protein Belongs to the UPF0296 family gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01779 BSBS38_01780 BSBS38_01780 BSBS38_01780 1675789 1676403 + Guanylate kinase Essential for recycling GMP and indirectly%2C cGMP%3B Belongs to the guanylate kinase family%3B Contains 1 guanylate kinase-like domain%3B KEGG: bsu:BSU15680 guanylate kinase gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01780 BSBS38_01781 BSBS38_01781 rpoZ rpoZ 1676407 1676610 + DNA-directed RNA polymerase Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits%3B Belongs to the RNA polymerase subunit omega family%3B KEGG: bsu:BSU15690 DNA-directed RNA polymerase subunit omega gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01781 BSBS38_01782 BSBS38_01782 BSBS38_01782 1676693 1677913 + Phosphopantothenoylcysteine decarboxylase Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C in the latter compound is decarboxylated to form 4'-phosphopantotheine (By similarity)%3B In the N-terminal sectio%3B belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily%3B In the C-terminal sectio%3B belongs to the PPC synthetase family%3B KEGG: mht:D648_3290 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01782 BSBS38_01783 BSBS38_01783 priA priA 1677910 1680327 + Primosomal protein N' Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex%2C via its helicase activity%2C and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA%3B Belongs to the helicase family. PriA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU15710 primosomal protein N' (replication factor Y) (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01783 BSBS38_01784 BSBS38_01784 BSBS38_01784 1680354 1680836 + Peptide deformylase Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)%3B Belongs to the polypeptide deformylase family%3B KEGG: bsu:BSU15720 peptide deformylase gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01784 BSBS38_01785 BSBS38_01785 BSBS38_01785 1680841 1681794 + Methionyl-tRNA formyltransferase Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP%3B Belongs to the Fmt family%3B KEGG: caj:CIG1485E_1484 methionyl-tRNA formyltransferase gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01785 BSBS38_01786 BSBS38_01786 rsmB rsmB 1681781 1683124 + 16S rRNA (cytosine(967)-C(5))-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family%3B KEGG: bsu:BSU15740 16S rRNA (cytosine967-C5)-methyltransferase gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01786 BSBS38_01787 BSBS38_01787 rlmN rlmN 1683128 1684219 + 23S rRNA (adenine(2503)-C(2))-methyltransferase Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs%3B Belongs to the radical SAM superfamily. RlmN family%3B KEGG: bsu:BSU15750 23S rRNA (adenine2503-C2)-methyltransferase gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01787 BSBS38_01788 BSBS38_01788 BSBS38_01788 1684226 1684990 + Protein-serine/threonine phosphatase Protein phosphatase that dephosphorylates PrkC and FusA (elongation factor G). PrpC and prkC are cotranscribed%2C which suggests that they form a functional couple in vivo%2C PrpC's primary role being possibly to counter the action of PrkC. May be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU15760 protein phosphatase gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01788 BSBS38_01789 BSBS38_01789 BSBS38_01789 1684984 1686930 + Non-specific serine/threonine protein kinase Protein kinase that is responsible for triggering spore germination in response to muropeptides%2C signaling bacteria to exit dormancy. Autophosphorylates and phosphorylates FusA (EF-G%2C elongation factor G%3B the latter modification is likely necessary for germination in response to peptidoglycan. PrkC is a substrate in vitro of the cotranscribed phosphatase PrpC%2C which suggests that they form a functional couple in vivo. Might also be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 3 PASTA domains%3B Contains 1 protein kinase domain%3B KEGG: bsu:BSU15770 serine/threonine protein kinase%2C bacterial gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01789 BSBS38_01790 BSBS38_01790 rsgA rsgA 1686945 1687841 + Putative ribosome bioproteinis GTPase RsgA May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain%3B KEGG: bsu:BSU15780 ribosome biogenesis GTPase%3B In phosphorus-containing anhydrides gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01790 BSBS38_01791 BSBS38_01791 BSBS38_01791 1687846 1688499 + Ribulose-phosphate 3-epimerase Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate%3B Belongs to the ribulose-phosphate 3-epimerase family%3B KEGG: rme:Rmet_1510 ribulose-phosphate 3-epimerase gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01791 BSBS38_01792 BSBS38_01792 thiN thiN 1688572 1689216 + Thiamine diphosphokinase Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Belongs to the thiamine pyrophosphokinase family%3B KEGG: bsu:BSU15800 thiamine pyrophosphokinase gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01792 BSBS38_01793 BSBS38_01793 BSBS38_01793 1689441 1689629 - 50S ribosomal protein L28 Belongs to the ribosomal protein L28P family gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01793 BSBS38_01794 BSBS38_01794 BSBS38_01794 1689906 1690268 + uncharacterized protein Belongs to the asp23 family gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01794 BSBS38_01795 BSBS38_01795 BSBS38_01795 1690284 1691945 + uncharacterized protein Contains 1 DhaL domain gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01795 BSBS38_01796 BSBS38_01796 sdaA sdaA 1692084 1692746 + L-serine ammonia-lyase Belongs to the iron-sulfur dependent L-serine dehydratase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU15850 L-serine dehydratase gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01796 BSBS38_01797 BSBS38_01797 BSBS38_01797 1692772 1693674 + L-serine ammonia-lyase Belongs to the iron-sulfur dependent L-serine dehydratase family%3B KEGG: bsu:BSU15860 L-serine dehydratase gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01797 BSBS38_01798 BSBS38_01798 recG recG 1693652 1695700 + DNA helicase Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) (By similarity)%3B Belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU15870 ATP-dependent DNA helicase RecG gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01798 BSBS38_01799 BSBS38_01799 BSBS38_01799 1695809 1696375 + Transcription factor FapR Transcription factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. Binds to the 5'-TTAGTANNNNNTANTAA-3' consensus sequence found in the promoter of fabHAF operon (containing fabHA and fabF genes)%2C yhdO and fapR genes and prevents their expression. Its action is probably modulated by malonyl-CoA%3B Belongs to the FapR family gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01799 BSBS38_01800 BSBS38_01800 plsX plsX 1696389 1697390 + Glycerol-3-phosphate 1-O-acyltransferase Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the PlsX family%3B KEGG: sdn:Sden_2296 glycerol-3-phosphate acyltransferase PlsX gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01800 BSBS38_01801 BSBS38_01801 fabD fabD 1697409 1698362 + [Acyl-carrier-protein] S-malonyltransferase Belongs to the FabD family%3B KEGG: rah:Rahaq_2956 (acyl-carrier-protein) S-malonyltransferase gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01801 BSBS38_01802 BSBS38_01802 BSBS38_01802 1698355 1699095 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ahd:AI20_12755 3-oxoacyl-(acyl-carrier protein) reductase gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01802 BSBS38_01803 BSBS38_01803 BSBS38_01803 1699179 1699412 + Acyl carrier protein Carrier of the growing fatty acid chain in fatty acid biosynthesis%3B Contains 1 acyl carrier domain gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01803 BSBS38_01804 BSBS38_01804 rnt1 rnt1 1699552 1700301 + Ribonuclease III Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs%2C and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism%3B Contains 1 DRBM (double-stranded RNA-binding) domain%3B Contains 1 RNase III domain%3B KEGG: bsu:BSU15930 ribonuclease III gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01804 BSBS38_01805 BSBS38_01805 BSBS38_01805 1700402 1703962 + Chromosome partition protein Smc Required for chromosome condensation and partitioning%3B Belongs to the SMC family gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01805 BSBS38_01806 BSBS38_01806 BSBS38_01806 1703982 1704971 + Signal recognition particle receptor FtsY Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)%3B Belongs to the GTP-binding SRP family. FtsY subfamily gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01806 BSBS38_01807 BSBS38_01807 BSBS38_01807 1705007 1705492 - uncharacterized protein gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01807 BSBS38_01808 BSBS38_01808 BSBS38_01808 1705670 1706002 + UPF0122 protein Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein%3B Belongs to the UPF0122 family gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01808 BSBS38_01809 BSBS38_01809 BSBS38_01809 1706016 1707356 + Signal recognition particle protein Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane%2C the hydrolysis of GTP by both Ffh and FtsY%2C and the dissociation of the SRP-FtsY complex into the individual components (Probable)%3B Belongs to the GTP-binding SRP family. SRP54 subfamily gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01809 BSBS38_01810 BSBS38_01810 BSBS38_01810 1707462 1707734 + 30S ribosomal protein S16 Belongs to the ribosomal protein S16P family gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01810 BSBS38_01811 BSBS38_01811 BSBS38_01811 1707734 1707979 + UPF0109 protein YlqC Belongs to the UPF0109 family%3B Contains 1 KH domain gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01811 BSBS38_01812 BSBS38_01812 BSBS38_01812 1708101 1708487 + uncharacterized protein gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01812 BSBS38_01813 BSBS38_01813 BSBS38_01813 1708492 1709016 + Ribosome maturation factor RimM An accessory protein needed during the final step in the assembly of 30S ribosomal subunit%2C possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes%3B Belongs to the RimM family%3B Contains 1 PRC barrel domain gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01813 BSBS38_01814 BSBS38_01814 trmD trmD 1709013 1709744 + tRNA (guanine(37)-N(1))-methyltransferase Specifically methylates guanosine-37 in various tRNAs%3B Belongs to the RNA methyltransferase TrmD family%3B KEGG: dno:DNO_1009 tRNA (guanine37-N1)-methyltransferase gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01814 BSBS38_01815 BSBS38_01815 BSBS38_01815 1709884 1710231 + 50S ribosomal protein L19 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site%3B Belongs to the ribosomal protein L19P family gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01815 BSBS38_01816 BSBS38_01816 BSBS38_01816 1710374 1711222 + Ribosome bioproteinis GTPase Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. Binds to the 23S rRNA (By similarity)%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01816 BSBS38_01817 BSBS38_01817 rnhB rnhB 1711293 1712060 + Ribonuclease H Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family%3B KEGG: bsu:BSU16060 ribonuclease HII gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01817 BSBS38_01818 BSBS38_01818 BSBS38_01818 1712092 1713822 + uncharacterized protein overlaps another CDS with the same product name gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01818 BSBS38_01819 BSBS38_01819 BSBS38_01819 1713819 1714100 + uncharacterized protein overlaps another CDS with the same product name gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01819 BSBS38_01820 BSBS38_01820 sucC sucC 1714273 1715430 + Succinate--CoA ligase (ADP-forming) Belongs to the succinate/malate CoA ligase beta subunit family%3B Contains 1 ATP-grasp domain%3B KEGG: hap:HAPS_0656 succinyl-CoA synthetase beta subunit gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01820 BSBS38_01821 BSBS38_01821 mtkB mtkB 1715459 1716361 + Malate--CoA ligase Belongs to the succinate/malate CoA ligase alpha subunit family%3B KEGG: mmt:Metme_2693 malate-CoA ligase subunit alpha gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01821 BSBS38_01822 BSBS38_01822 BSBS38_01822 1716422 1717315 + Protein smf Belongs to the smf family gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01822 BSBS38_01823 BSBS38_01823 topA topA 1717503 1719578 + DNA topoisomerase Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU16120 DNA topoisomerase I gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01823 BSBS38_01824 BSBS38_01824 BSBS38_01824 1719654 1720961 + Methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase(FADH(2)-oxidizing) Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs%3B Belongs to the MnmG family. TrmFO subfamily%3B KEGG: bsu:BSU16130 methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01824 BSBS38_01825 BSBS38_01825 BSBS38_01825 1721029 1721943 + Tyrosine recombinase XerC Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01825 BSBS38_01826 BSBS38_01826 hslV hslV 1721956 1722501 + HslU--HslV peptidase Protease subunit of a proteasome-like degradation complex%3B Belongs to the peptidase T1B family. HslV subfamily%3B KEGG: rhd:R2APBS1_3955 ATP-dependent HslUV protease%2C peptidase subunit HslV gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01826 BSBS38_01827 BSBS38_01827 BSBS38_01827 1722518 1723921 + ATP-dependent protease ATPase subunit ClpY ATPase subunit of a proteasome-like degradation comple%3B this subunit has chaperone activity%3B Belongs to the ClpX chaperone family. HslU subfamily gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01827 BSBS38_01828 BSBS38_01828 BSBS38_01828 1723961 1724740 + GTP-sensing transcriptional pleiotropic repressor CodY DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor%3B Belongs to the CodY family gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01828 BSBS38_01829 BSBS38_01829 BSBS38_01829 1725120 1725509 + Flagellar basal body rod protein FlgB Structural component of flagellum%2C the bacterial motility apparatus. Part of the rod structure of flagellar basal body%3B Belongs to the flagella basal body rod proteins family gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01829 BSBS38_01830 BSBS38_01830 BSBS38_01830 1725509 1725961 + Flagellar basal-body rod protein FlgC Belongs to the flagella basal body rod proteins family gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01830 BSBS38_01831 BSBS38_01831 BSBS38_01831 1725972 1726292 + Flagellar hook-basal body complex protein FliE Belongs to the FliE family gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01831 BSBS38_01832 BSBS38_01832 BSBS38_01832 1726338 1727948 + Flagellar M-ring protein The M ring may be actively involved in energy transduction. Belongs to the FliF family gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01832 BSBS38_01833 BSBS38_01833 BSBS38_01833 1727961 1728143 + Flagellar motor switch protein FliG One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliG family gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01833 BSBS38_01834 BSBS38_01834 BSBS38_01834 1728275 1728976 + Flagellar motor switch protein FliG One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliG family gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01834 BSBS38_01835 BSBS38_01835 BSBS38_01835 1728960 1729721 + putative flagellar assembly protein FliH Needed for flagellar regrowth and assembly. Belongs to the FliH family gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01835 BSBS38_01836 BSBS38_01836 fliI fliI 1729718 1731034 + H(+)-transporting two-sector ATPase Probable catalytic subunit of a protein translocase for flagellum-specific export%2C or a proton translocase involved in local circuits at the flagellum. Belongs to the ATPase alpha/beta chains family%3B KEGG: bsu:BSU16240 flagellum-specific ATP synthase gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01836 BSBS38_01837 BSBS38_01837 BSBS38_01837 1731037 1731480 + Flagellar FliJ protein Flagellar protein that affects chemotactic events%3B Belongs to the FliJ family gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01837 BSBS38_01838 BSBS38_01838 BSBS38_01838 1731492 1732106 + FlaA locus 22.9 kDa protein gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01838 BSBS38_01839 BSBS38_01839 BSBS38_01839 1732119 1733582 + putative flagellar hook-length control protein Controls the length of the flagellar hook%3B Belongs to the FliK family gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01839 BSBS38_01840 BSBS38_01840 BSBS38_01840 1733579 1734001 + FlaA locus uncharacterized protein YlxG Belongs to the FlgD family gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01840 BSBS38_01841 BSBS38_01841 BSBS38_01841 1734023 1734817 + Flagellar hook protein FlgE Belongs to the flagella basal body rod proteins family gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01841 BSBS38_01842 BSBS38_01842 BSBS38_01842 1735069 1735491 + Flagellar protein FliL Controls the rotational direction of flagella during chemotaxis. Belongs to the FliL family gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01842 BSBS38_01843 BSBS38_01843 BSBS38_01843 1735525 1736523 + Flagellar motor switch protein FliM One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliM family gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01843 BSBS38_01844 BSBS38_01844 BSBS38_01844 1736513 1737649 + Flagellar motor switch phosphatase FliY Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attractant to cope with increased levels of CheY-P%3B Belongs to the FliN/MopA/SpaO family gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01844 BSBS38_01845 BSBS38_01845 BSBS38_01845 1737675 1738037 + Chemotaxis protein CheY Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY%2C which causes counterclockwise rotation of the flagella%2C resulting in smooth swimming%3B Contains 1 response regulatory domain gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01845 BSBS38_01846 BSBS38_01846 BSBS38_01846 1738052 1738711 + Flagellar biosynthetic protein FliZ gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01846 BSBS38_01847 BSBS38_01847 BSBS38_01847 1738704 1739369 + Flagellar biosynthetic protein FliP Plays a role in the flagellum-specific transport system%3B Belongs to the FliP/MopC/SpaP family gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01847 BSBS38_01848 BSBS38_01848 BSBS38_01848 1739384 1739653 + Flagellar biosynthetic protein FliQ Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01848 BSBS38_01849 BSBS38_01849 BSBS38_01849 1739661 1740440 + Flagellar biosynthetic protein FliR Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01849 BSBS38_01850 BSBS38_01850 BSBS38_01850 1740440 1741522 + Flagellar biosynthetic protein FlhB May be involved in the export of flagellum proteins. Belongs to the type III secretion exporter family gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01850 BSBS38_01851 BSBS38_01851 BSBS38_01851 1741555 1743588 + Flagellar biosynthesis protein FlhA Involved in the export of flagellum proteins. Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01851 BSBS38_01852 BSBS38_01852 BSBS38_01852 1743588 1744688 + Flagellar biosynthesis protein FlhF Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. Belongs to the GTP-binding SRP family gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01852 BSBS38_01853 BSBS38_01853 BSBS38_01853 1744685 1745575 + Flagellum site-determining protein YlxH Involved in the placement and assembly of flagella (By similarity). Activates the SRP-GTPase activity of FlhF%3B Belongs to the ParA family gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01853 BSBS38_01854 BSBS38_01854 BSBS38_01854 1745577 1746650 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01854 BSBS38_01855 BSBS38_01855 cheA cheA 1746656 1748674 + Histidine kinase Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylate%3B it can transfer its phosphate group to CheB%2C CheY or CheV%3B Contains 1 cheW-like domain%3B Contains 1 histidine kinase domain%3B Contains 1 HPt domain%3B KEGG: xcc:XCC2700 two-component system%2C chemotaxis family%2C sensor kinase CheA gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01855 BSBS38_01856 BSBS38_01856 BSBS38_01856 1748696 1749166 + Chemotaxis protein CheW Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis%3B Contains 1 cheW-like domain gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01856 BSBS38_01857 BSBS38_01857 BSBS38_01857 1749185 1749814 + CheY-P phosphatase CheC Involved in restoring normal CheY-P levels following the addition of attractant by increasing the rate of CheY-P hydrolysis. Is only 6%25 as active as FliY%2C which indicates that CheC may function after addition of an attractant to cope with increased levels of CheY-P whereas FliY may function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P. In addition%2C it was shown to prevent methylation of the methyl-accepting chemotaxis proteins (MCPs). Inhibits CheD%3B Belongs to the CheC family gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01857 BSBS38_01858 BSBS38_01858 cheD cheD 1749811 1750311 + Protein-glutamine glutaminase Deamidates 'Gln-593' and 'Gln-594' of the chemoreceptor McpA. In addition%2C deamidates other chemoreceptors%2C including McpB and McpC. CheD-mediated MCP (methyl-accepting chemotaxis proteins) deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase. CheD is absolutely required for a behavioral response mediated by McpC but is not required for the response to asparagine mediated by McpB. CheD is necessary for the generation of wild-type prestimulus CheA autophosphorylation levels. Also required for methylation of MCPs by CheR. In addition%2C enhances the activity of CheC 5-fold in vitro%3B Belongs to the CheD family%3B KEGG: bsu:BSU16460 chemotaxis protein CheD gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01858 BSBS38_01859 BSBS38_01859 BSBS38_01859 1750334 1751098 + RNA polymerase sigma-D factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This alternative sigma factor is required for the transcription of the flagellin and motility genes as well as for wild-type chemotaxis. Belongs to the sigma-70 factor family gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01859 BSBS38_01860 BSBS38_01860 BSBS38_01860 1751127 1751630 + Swarming motility protein SwrB Required for swarming motility and for maximal sigma-D activity gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01860 BSBS38_01861 BSBS38_01861 BSBS38_01861 1751774 1752514 + 30S ribosomal protein S2 Belongs to the ribosomal protein S2P family gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01861 BSBS38_01862 BSBS38_01862 BSBS38_01862 1752616 1753497 + Elongation factor Ts Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA. EF- Tu. GTP complex up to the GTP hydrolysis stage on the ribosome%3B Belongs to the EF-Ts family gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01862 BSBS38_01863 BSBS38_01863 pyrH pyrH 1753643 1754365 + UMP kinase Catalyzes the reversible phosphorylation of UMP to UDP%2C with ATP or dATP as the most efficient phosphate donors. Is also able to phosphorylate 5-fluoro-UMP and 6-aza-UMP%3B Belongs to the UMP kinase family%3B KEGG: bsu:BSU16510 uridylate kinase gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01863 BSBS38_01864 BSBS38_01864 BSBS38_01864 1754367 1754924 + Ribosome-recycling factor Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another%3B Plays a role in sporulation%3B Belongs to the RRF family gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01864 BSBS38_01865 BSBS38_01865 uppS uppS 1755055 1755837 + Ditrans%2Cpolycis-undecaprenyl-diphosphate synthase ((2E%2C6E)-farnesyl-diphosphate specific) Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids%3B Belongs to the UPP synthase family%3B KEGG: bsu:BSU16530 undecaprenyl diphosphate synthase gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01865 BSBS38_01866 BSBS38_01866 cds1 cds1 1755850 1756650 + Phosphatidate cytidylyltransferase Belongs to the CDS family%3B KEGG: bsu:BSU16540 phosphatidate cytidylyltransferase gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01866 BSBS38_01867 BSBS38_01867 BSBS38_01867 1756712 1757863 + 1-deoxy-D-xylulose-5-phosphate reductoisomerase Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)%3B Belongs to the DXR family%3B KEGG: pat:Patl_1255 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01867 BSBS38_01868 BSBS38_01868 rseP rseP 1757876 1759138 + putative protease eep Involved in production of the peptide pheromone cAD1. Belongs to the peptidase M50B family%3B Contains 1 PDZ (DHR) domain%3B KEGG: tcx:Tcr_1279 regulator of sigma E protease%3B Metalloendopeptidases gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01868 BSBS38_01869 BSBS38_01869 parS parS 1759171 1760865 + Proline--tRNA ligase Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine%2C to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS%3B Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily%3B KEGG: bsu:BSU16570 prolyl-tRNA synthetase gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01869 BSBS38_01870 BSBS38_01870 polC polC 1760923 1765287 + DNA-directed DNA polymerase Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Belongs to the DNA polymerase type-C family. PolC subfamily%3B Contains 1 exonuclease domain%3B KEGG: bsut:BSUB_01790 DNA polymerase III subunit alpha%2C Gram-positive type gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01870 BSBS38_01871 BSBS38_01871 BSBS38_01871 1765617 1766087 + Ribosome maturation factor RimP Required for maturation of 30S ribosomal subunits%3B Belongs to the RimP family gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01871 BSBS38_01872 BSBS38_01872 BSBS38_01872 1766122 1767237 + Transcription termination/antitermination protein NusA Participates in both transcription termination and antitermination%3B Belongs to the NusA family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01872 BSBS38_01873 BSBS38_01873 BSBS38_01873 1767251 1767526 + uncharacterized protein gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01873 BSBS38_01874 BSBS38_01874 BSBS38_01874 1767528 1767830 + putative ribosomal protein YlxQ RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA%2C but also in box C/D and box C'/D' sRNAs%3B Belongs to the ribosomal protein L7Ae family gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01874 BSBS38_01875 BSBS38_01875 BSBS38_01875 1767850 1770000 + Translation initiation factor IF-2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01875 BSBS38_01876 BSBS38_01876 BSBS38_01876 1769997 1770275 + uncharacterized protein gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01876 BSBS38_01877 BSBS38_01877 BSBS38_01877 1770292 1770645 + Ribosome-binding factor Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA%3B Belongs to the RbfA family gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01877 BSBS38_01878 BSBS38_01878 truB truB 1770727 1771656 + tRNA pseudouridine(55) synthase Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs%3B Belongs to the pseudouridine synthase TruB family. Type 1 subfamily%3B KEGG: ben:BOBLI757_107 tRNA pseudouridine55 synthase gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01878 BSBS38_01879 BSBS38_01879 ribF ribF 1771675 1772625 + Riboflavin kinase Belongs to the RibF family%3B KEGG: bsu:BSU16670 riboflavin kinase / FMN adenylyltransferase gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01879 BSBS38_01880 BSBS38_01880 BSBS38_01880 1772782 1773051 + 30S ribosomal protein S15 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA%3B Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome%3B Belongs to the ribosomal protein S15P family gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01880 BSBS38_01881 BSBS38_01881 BSBS38_01881 1773224 1775341 + Polyribonucleotide nucleotidyltransferase Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction%3B Belongs to the polyribonucleotide nucleotidyltransferase family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain%3B KEGG: bsu:BSU16690 polyribonucleotide nucleotidyltransferase gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01881 BSBS38_01882 BSBS38_01882 BSBS38_01882 1775458 1776417 + uncharacterized protein Belongs to the polysaccharide deacetylase family%3B KEGG: bmet:BMMGA3_03310 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01882 BSBS38_01883 BSBS38_01883 pqqL pqqL 1776457 1777686 + putative zinc protease YmxG Belongs to the peptidase M16 family%3B KEGG: ftu:FTT_1321 zinc protease%3B Metalloendopeptidases gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01883 BSBS38_01884 BSBS38_01884 BSBS38_01884 1777764 1778021 + uncharacterized protein Belongs to the YlmC/YmxH family gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01884 BSBS38_01885 BSBS38_01885 BSBS38_01885 1778207 1779100 + Dipicolinate synthase subunit Together with DpaB%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01885 BSBS38_01886 BSBS38_01886 BSBS38_01886 1779103 1779705 + Dipicolinate synthase subunit Together with DpaA%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01886 BSBS38_01887 BSBS38_01887 BSBS38_01887 1779831 1780871 + Aspartate-semialdehyde dehydrogenase Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate%3B Belongs to the aspartate-semialdehyde dehydrogenase family%3B KEGG: bsu:BSU16750 aspartate-semialdehyde dehydrogenase gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01887 BSBS38_01888 BSBS38_01888 BSBS38_01888 1780963 1782177 + Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU16760 aspartate kinase gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01888 BSBS38_01889 BSBS38_01889 dapA dapA 1782208 1783080 + 4-hydroxy-tetrahydrodipicolinate synthase Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: bsu:BSU16770 4-hydroxy-tetrahydrodipicolinate synthase gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01889 BSBS38_01890 BSBS38_01890 BSBS38_01890 1783258 1784925 + Ribonuclease J2 Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Plays a role in mRNA maturation and stability. Appears to have a limited effect on 16S rRNA maturation%2C despite its similarity to RNase J1. This subunit alone has very poor 5'-3' exonuclease activity%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bsu:BSU16780 ribonuclease J%3B Acting on ester bonds gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01890 BSBS38_01891 BSBS38_01891 clpP clpP 1785041 1785778 + Endopeptidase Clp Required for efficient translocation of pre-proteins across the membrane%3B Belongs to the peptidase S14 family. TepA subfamily%3B KEGG: nth:Nther_1461 ATP-dependent Clp protease%2C protease subunit gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01891 BSBS38_01892 BSBS38_01892 BSBS38_01892 1785775 1785987 + uncharacterized protein gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01892 BSBS38_01893 BSBS38_01893 BSBS38_01893 1786118 1788481 + DNA translocase SpoIIIE Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation%2C for the final steps of compartmentalization in the presence of trapped DNA%2C and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA in an ATP-dependent manner from mother cell into the forespore. DNA-binding proteins are stripped off the chromosome during translocation%2C which may play a key role in reprogramming developmental gene expression in the forespore. The two arms of the chromosome are simultaneously pumped into the forespore%2C which suggests that the septum contains at least two channels%2C one for each arm. Required for separation of chromosome termini. Also required for optimal chromosome partitioning in vegetative cells%2C by actively moving chromosomal DNA trapped within the division septum into the daughter cells%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01893 BSBS38_01894 BSBS38_01894 BSBS38_01894 1788625 1789350 + putative HTH-type transcriptional regulator YmfC Contains 1 HTH gntR-type DNA-binding domain gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01894 BSBS38_01895 BSBS38_01895 BSBS38_01895 1789489 1790700 + Bacillibactin exporter Involved in secretion of bacillibactin%3B Belongs to the major facilitator superfamily gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01895 BSBS38_01896 BSBS38_01896 BSBS38_01896 1790880 1792160 + putative inactive metalloprotease YmfF Belongs to the peptidase M16 family%3B KEGG: tid:Thein_0626 zinc protease%3B Metalloendopeptidases gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01896 BSBS38_01897 BSBS38_01897 BSBS38_01897 1792157 1793443 + Insulysin Belongs to the peptidase M16 family%3B KEGG: bcz:BCZK3546 insulysin gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01897 BSBS38_01898 BSBS38_01898 ptr1 ptr1 1793498 1794226 + Pteridine reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: mct:MCR_0453 pteridine reductase gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01898 BSBS38_01899 BSBS38_01899 BSBS38_01899 1794307 1794564 + uncharacterized protein gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01899 BSBS38_01900 BSBS38_01900 BSBS38_01900 1794694 1795485 + uncharacterized protein Contains 1 ACT domain gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01900 BSBS38_01901 BSBS38_01901 BSBS38_01901 1795504 1796418 + putative membrane protein YmfM gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01901 BSBS38_01902 BSBS38_01902 pgsA pgsA 1796468 1797049 + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase This protein catalyzes the committed step to the synthesis of the acidic phospholipids%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: bsu:BSU16920 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01902 BSBS38_01903 BSBS38_01903 pncC pncC 1797067 1798317 + Nicotinamide-nucleotide amidase Belongs to the CinA family%3B KEGG: bsu:BSU16930 nicotinamide-nucleotide amidase gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01903 BSBS38_01904 BSBS38_01904 BSBS38_01904 1798490 1799536 + Protein RecA It interacts with LexA causing its activation and leading to its autocatalytic cleavage%3B Belongs to the RecA family gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01904 BSBS38_01905 BSBS38_01905 BSBS38_01905 1799703 1800878 + Serine-type D-Ala-D-Ala carboxypeptidase Belongs to the beta-lactamase family%3B KEGG: aoi:AORI_0128 D-alanyl-D-alanine carboxypeptidase gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01905 BSBS38_01906 BSBS38_01906 BSBS38_01906 1801154 1802716 + Ribonuclease Endoribonuclease that initiates mRNA decay. Initiates the decay of all SAM-dependent riboswitches%2C such as yitJ riboswitch. Involved in processing of the gapA operon mRNA%2C it cleaves between cggR and gapA (PubMed:19193632). Is also the decay-initiating endonuclease for rpsO mRNA%3B Belongs to the RNase Y family%3B Contains 1 HD domain%3B Contains 1 KH domain%3B KEGG: bsu:BSU16960 ribonucrease Y%3B Acting on ester bonds gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01906 BSBS38_01907 BSBS38_01907 BSBS38_01907 1802785 1803579 + uncharacterized protein gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01907 BSBS38_01908 BSBS38_01908 BSBS38_01908 1803779 1804039 + Stage V sporulation protein gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01908 BSBS38_01909 BSBS38_01909 BSBS38_01909 1804304 1805347 + L-threonine 3-dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU16990 threonine 3-dehydrogenase gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01909 BSBS38_01910 BSBS38_01910 gcaT gcaT 1805360 1806538 + Glycine C-acetyltransferase Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bsu:BSU17000 glycine C-acetyltransferase gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01910 BSBS38_01911 BSBS38_01911 miaB miaB 1806686 1808215 + tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A)%2C leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine%3B Belongs to the methylthiotransferase family. MiaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU17010 tRNA-2-methylthio-N6-dimethylallyladenosine synthase gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01911 BSBS38_01912 BSBS38_01912 BSBS38_01912 1808217 1808648 + Polar-amino-acid-transporting ATPase May work together with YlbF to regulate community development%3B KEGG: cml:BN424_2091 polar amino acid transport system ATP-binding protein gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01912 BSBS38_01913 BSBS38_01913 BSBS38_01913 1808910 1809455 + Spore coat protein Morphogenic protein required for the assembly of the outer coat of the endospore. Is also a regulatory protein for the expression of cotA%2C cotB%2C cotC%2C cotH and other genes encoding spore outer coat proteins%3B Belongs to the CotE family gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01913 BSBS38_01914 BSBS38_01914 BSBS38_01914 1809588 1812164 + DNA mismatch repair protein MutS This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity%3B Belongs to the DNA mismatch repair MutS family gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01914 BSBS38_01915 BSBS38_01915 BSBS38_01915 1812174 1814063 + DNA mismatch repair protein MutL This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker'%2C a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex%3B Belongs to the DNA mismatch repair MutL/HexB family gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01915 BSBS38_01916 BSBS38_01916 BSBS38_01916 1814625 1815062 + hypothetical protein gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01916 BSBS38_01917 BSBS38_01917 BSBS38_01917 1815173 1815421 + hypothetical protein gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01917 BSBS38_01918 BSBS38_01918 BSBS38_01918 1815472 1815834 - uncharacterized protein gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01918 BSBS38_01919 BSBS38_01919 BSBS38_01919 1816051 1816809 - Insertion sequence IS21 putative ATP-binding protein One of two proteins expressed only when there is a tandem repeat of the IS21 insertion sequence%2C it is necessary for the transposition of plasmids with that tandem repeat. Belongs to the IS21/IS1162 putative ATP-binding protein family gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01919 BSBS38_01920 BSBS38_01920 BSBS38_01920 1816806 1818353 - Transposase for insertion sequence element IS21-like protein Involved in the transposition of the insertion sequence%3B Belongs to the transposase IS21/IS408/IS1162 family%3B Contains 1 HTH IS21-type DNA-binding domain%3B Contains 1 integrase catalytic domain gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01920 BSBS38_01921 BSBS38_01921 BSBS38_01921 1818748 1819986 + Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01921 BSBS38_01922 BSBS38_01922 BSBS38_01922 1820026 1820718 + hypothetical protein gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01922 BSBS38_01923 BSBS38_01923 BSBS38_01923 1820955 1821365 + hypothetical protein gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01923 BSBS38_01924 BSBS38_01924 BSBS38_01924 1821449 1821865 + putative integrase/recombinase YoeC Belongs to the 'phage' integrase family gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01924 BSBS38_01925 BSBS38_01925 BSBS38_01925 1822164 1822316 + hypothetical protein gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01925 BSBS38_01926 BSBS38_01926 BSBS38_01926 1822644 1822793 + hypothetical protein gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01926 BSBS38_01927 BSBS38_01927 BSBS38_01927 1822862 1823179 + hypothetical protein gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01927 BSBS38_01928 BSBS38_01928 BSBS38_01928 1823340 1823504 + hypothetical protein gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01928 BSBS38_01929 BSBS38_01929 BSBS38_01929 1823589 1824203 + hypothetical protein gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01929 BSBS38_01930 BSBS38_01930 BSBS38_01930 1824216 1824440 + hypothetical protein gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01930 BSBS38_01931 BSBS38_01931 BSBS38_01931 1824437 1824811 + hypothetical protein gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01931 BSBS38_01932 BSBS38_01932 BSBS38_01932 1824811 1825119 + hypothetical protein gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01932 BSBS38_01933 BSBS38_01933 BSBS38_01933 1825191 1825724 + hypothetical protein gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01933 BSBS38_01934 BSBS38_01934 BSBS38_01934 1825724 1825891 + hypothetical protein gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01934 BSBS38_01935 BSBS38_01935 BSBS38_01935 1825975 1827213 - Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01935 BSBS38_01936 BSBS38_01936 BSBS38_01936 1828269 1828724 - uncharacterized protein gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01936 BSBS38_01937 BSBS38_01937 BSBS38_01937 1828970 1830175 + hypothetical protein gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01937 BSBS38_01938 BSBS38_01938 BSBS38_01938 1830318 1830461 - hypothetical protein gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01938 BSBS38_01939 BSBS38_01939 BSBS38_01939 1830463 1831020 - putative membrane protein YmcC gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01939 BSBS38_01940 BSBS38_01940 BSBS38_01940 1831141 1831755 + HTH-type transcriptional regulator PksA Transcriptional regulation of the polyketide synthase operon. Contains 1 HTH tetR-type DNA-binding domain gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01940 BSBS38_01941 BSBS38_01941 BSBS38_01941 1831891 1832247 - uncharacterized protein gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01941 BSBS38_01942 BSBS38_01942 BSBS38_01942 1832326 1833168 - uncharacterized protein gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01942 BSBS38_01943 BSBS38_01943 aprX aprX 1833261 1834589 - Serine protease AprX Displays serine protease activity. Seems to have a broad substrate specificity%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU17260 serine protease AprX%3B Serine endopeptidases gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01943 BSBS38_01944 BSBS38_01944 BSBS38_01944 1834814 1835047 + hypothetical protein gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01944 BSBS38_01945 BSBS38_01945 BSBS38_01945 1835327 1836034 + UPF0714 protein YmaC Belongs to the UPF0714 family gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01945 BSBS38_01946 BSBS38_01946 BSBS38_01946 1836104 1836556 + uncharacterized protein Belongs to the OsmC/Ohr family gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01946 BSBS38_01947 BSBS38_01947 BSBS38_01947 1836570 1836923 - Multidrug resistance protein EbrB Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01947 BSBS38_01948 BSBS38_01948 BSBS38_01948 1836937 1837257 - Multidrug resistance protein EbrA Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01948 BSBS38_01949 BSBS38_01949 BSBS38_01949 1837389 1837667 - uncharacterized protein gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01949 BSBS38_01950 BSBS38_01950 BSBS38_01950 1837765 1838169 + uncharacterized protein gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01950 BSBS38_01951 BSBS38_01951 miaA miaA 1838269 1839213 + tRNA dimethylallyltransferase Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine%2C leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)%3B Belongs to the IPP transferase family%3B KEGG: spiu:SPICUR_02785 tRNA dimethylallyltransferase gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01951 BSBS38_01952 BSBS38_01952 BSBS38_01952 1839253 1839474 + RNA-binding protein Hfq RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress%2C environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs%3B Belongs to the Hfq family gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01952 BSBS38_01953 BSBS38_01953 BSBS38_01953 1839669 1839941 + uncharacterized protein gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01953 BSBS38_01954 BSBS38_01954 BSBS38_01954 1840023 1840253 + uncharacterized protein gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01954 BSBS38_01955 BSBS38_01955 BSBS38_01955 1840586 1840888 + Protein NrdI Probably involved in ribonucleotide reductase function. Belongs to the NrdI family gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01955 BSBS38_01956 BSBS38_01956 nrdA nrdA 1840848 1842950 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bsu:BSU17380 ribonucleoside-diphosphate reductase alpha chain gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01956 BSBS38_01957 BSBS38_01957 nrdB nrdB 1842968 1843957 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bsu:BSU17390 ribonucleoside-diphosphate reductase beta chain gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01957 BSBS38_01958 BSBS38_01958 BSBS38_01958 1844007 1844627 + uncharacterized protein gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01958 BSBS38_01959 BSBS38_01959 BSBS38_01959 1844691 1845458 - N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01959 BSBS38_01960 BSBS38_01960 BSBS38_01960 1846099 1847067 + Stage V sporulation protein Belongs to the cbxX/cfxQ family gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01960 BSBS38_01961 BSBS38_01961 BSBS38_01961 1847200 1848462 + GTPase HflX GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family%3B Contains 1 Hflx-type G (guanine nucleotide-binding) domain gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01961 BSBS38_01962 BSBS38_01962 BSBS38_01962 1848480 1849745 + Cystathionine gamma-lyase KEGG: ava:Ava_4213 cystathionine gamma-lyase gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01962 BSBS38_01963 BSBS38_01963 BSBS38_01963 1849855 1850262 + HTH-type transcriptional regulator GlnR Represses many genes including the glnRA operon and tnrA during growth with nitrogen excess%3B Contains 1 HTH merR-type DNA-binding domain gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01963 BSBS38_01964 BSBS38_01964 glnA glnA 1850321 1851655 + Glutamate--ammonia ligase Belongs to the glutamine synthetase family%3B KEGG: bso:BSNT_02802 glutamine synthetase gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01964 BSBS38_01965 BSBS38_01965 BSBS38_01965 1851929 1852228 - uncharacterized protein gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01965 BSBS38_01966 BSBS38_01966 BSBS38_01966 1852282 1852590 - hypothetical protein gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01966 BSBS38_01967 BSBS38_01967 BSBS38_01967 1852611 1854494 - Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01967 BSBS38_01968 BSBS38_01968 BSBS38_01968 1854743 1854922 + hypothetical protein gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01968 BSBS38_01969 BSBS38_01969 BSBS38_01969 1855586 1855876 + putative membrane protein YnxB gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01969 BSBS38_01970 BSBS38_01970 BSBS38_01970 1856115 1856606 + uncharacterized protein gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01970 BSBS38_01971 BSBS38_01971 BSBS38_01971 1856787 1857638 + Pesticidal crystal protein Cry6Ba Endotoxin with nematicidal activity. Belongs to the cry6A endotoxin family gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01971 BSBS38_01972 BSBS38_01972 BSBS38_01972 1857937 1858188 + UPF0457 protein YnzG Belongs to the UPF0457 family gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01972 BSBS38_01973 BSBS38_01973 BSBS38_01973 1858273 1858806 + uncharacterized protein gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01973 BSBS38_01974 BSBS38_01974 BSBS38_01974 1858876 1859145 + uncharacterized protein KEGG: vpk:M636_12535 5-methylcytosine-specific restriction enzyme A%3B Endodeoxyribonucleases producing 5'-phosphomonoesters%3B overlaps another CDS with the same product name gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01974 BSBS38_01975 BSBS38_01975 BSBS38_01975 1859090 1859524 + uncharacterized protein overlaps another CDS with the same product name gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01975 BSBS38_01976 BSBS38_01976 BSBS38_01976 1859744 1860982 + Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01976 BSBS38_01977 BSBS38_01977 BSBS38_01977 1861176 1861379 - hypothetical protein gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01977 BSBS38_01978 BSBS38_01978 BSBS38_01978 1861566 1862102 + Ribosomal-protein-alanine N-acetyltransferase Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: fgi:OP10G_2942 ribosomal-protein-alanine N-acetyltransferase gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01978 BSBS38_01979 BSBS38_01979 BSBS38_01979 1862089 1862235 + hypothetical protein gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01979 BSBS38_01980 BSBS38_01980 BSBS38_01980 1862181 1863083 + hypothetical protein gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01980 BSBS38_01981 BSBS38_01981 BSBS38_01981 1863161 1863541 + SPBc2 prophage-derived UPF0715 membrane protein YopD Belongs to the UPF0715 family gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01981 BSBS38_01982 BSBS38_01982 BSBS38_01982 1864083 1864313 + SPBc2 prophage-derived uncharacterized protein YopB gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01982 BSBS38_01983 BSBS38_01983 BSBS38_01983 1864310 1864438 + uncharacterized protein gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01983 BSBS38_01984 BSBS38_01984 BSBS38_01984 1864443 1864952 + uncharacterized protein gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01984 BSBS38_01985 BSBS38_01985 BSBS38_01985 1865008 1865226 + uncharacterized protein gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01985 BSBS38_01986 BSBS38_01986 BSBS38_01986 1865870 1865989 + putative membrane protein YnzI gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01986 BSBS38_01987 BSBS38_01987 trpF trpF 1866129 1866599 + Phosphoribosylanthranilate isomerase To L. lactis TrpF C-terminal region%3B KEGG: sgo:SGO_1194 phosphoribosylanthranilate isomerase gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01987 BSBS38_01988 BSBS38_01988 BSBS38_01988 1867395 1867922 + putative symporter YnaJ Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01988 BSBS38_01989 BSBS38_01989 BSBS38_01989 1867964 1868785 + putative symporter YnaJ Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01989 BSBS38_01990 BSBS38_01990 xynB xynB 1868816 1870417 + Xylan 1%2C4-beta-xylosidase Beta-xylosidase is an intracellular xylan-degrading enzyme. Belongs to the glycosyl hydrolase 43 family%3B KEGG: eco:b0271 xylan 1%2C4-beta-xylosidase gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01990 BSBS38_01991 BSBS38_01991 BSBS38_01991 1870555 1871709 - Xylose repressor Transcriptional repressor of xylose-utilizing enzymes. Belongs to the ROK (NagC/XylR) family gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01991 BSBS38_01992 BSBS38_01992 xylA xylA 1871947 1873284 + Xylose isomerase Belongs to the xylose isomerase family%3B KEGG: bsu:BSU17600 xylose isomerase gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01992 BSBS38_01993 BSBS38_01993 xylB xylB 1873435 1874934 + Xylulokinase Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: sod:Sant_1620 xylulokinase gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01993 BSBS38_01994 BSBS38_01994 BSBS38_01994 1875419 1876054 - Micrococcal nuclease Shows DNase activity on double strand DNA%3B Belongs to the thermonuclease family%3B KEGG: bsl:A7A1_3318 micrococcal nuclease gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01994 BSBS38_01995 BSBS38_01995 BSBS38_01995 1876467 1877882 + Putative metabolite transport protein YncC Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01995 BSBS38_01996 BSBS38_01996 BSBS38_01996 1877984 1879168 - Alanine racemase Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bsu:BSU17640 alanine racemase gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01996 BSBS38_01997 BSBS38_01997 BSBS38_01997 1879579 1880004 - hypothetical protein gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01997 BSBS38_01998 BSBS38_01998 BSBS38_01998 1880923 1881357 + dUTP diphosphatase This enzyme is involved in nucleotide metabolism: it produces dUMP%2C the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA%3B Belongs to the dUTPase family%3B KEGG: bso:BSNT_02916 dUTP pyrophosphatase gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01998 BSBS38_01999 BSBS38_01999 BSBS38_01999 1881483 1881656 - hypothetical protein gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_01999 BSBS38_02000 BSBS38_02000 BSBS38_02000 1882105 1883343 + Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02000 BSBS38_02001 BSBS38_02001 BSBS38_02001 1883368 1883598 - Spore coat protein To B. subtilis protein YnzH gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02001 BSBS38_02002 BSBS38_02002 BSBS38_02002 1884121 1884297 + hypothetical protein gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02002 BSBS38_02003 BSBS38_02003 thyA thyA 1884444 1885283 + Thymidylate synthase Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bsu:BSU17680 thymidylate synthase gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02003 BSBS38_02004 BSBS38_02004 BSBS38_02004 1885333 1885617 - hypothetical protein gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02004 BSBS38_02005 BSBS38_02005 BSBS38_02005 1885735 1886484 - uncharacterized protein To B. subtilis YrpD gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02005 BSBS38_02006 BSBS38_02006 BSBS38_02006 1886614 1886970 - putative membrane protein YnzK gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02006 BSBS38_02007 BSBS38_02007 BSBS38_02007 1887216 1887416 - Spore coat protein To B. subtilis protein YnzH gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02007 BSBS38_02008 BSBS38_02008 BSBS38_02008 1887591 1887779 - Sec-independent protein translocase protein TatAc Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system%3B Belongs to the TatA/E family gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02008 BSBS38_02009 BSBS38_02009 BSBS38_02009 1888033 1888431 + uncharacterized protein gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02009 BSBS38_02010 BSBS38_02010 BSBS38_02010 1888496 1888930 - uncharacterized protein Belongs to the AHA1 family gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02010 BSBS38_02011 BSBS38_02011 BSBS38_02011 1889237 1889425 + uncharacterized protein gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02011 BSBS38_02012 BSBS38_02012 BSBS38_02012 1889599 1889709 + hypothetical protein gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02012 BSBS38_02013 BSBS38_02013 BSBS38_02013 1889722 1890072 + putative membrane protein YndD Belongs to the GerABKA family gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02013 BSBS38_02014 BSBS38_02014 BSBS38_02014 1890104 1891027 + putative membrane protein YndD Belongs to the GerABKA family gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02014 BSBS38_02015 BSBS38_02015 BSBS38_02015 1891454 1891939 + Spore germination protein YndF May be involved in spore germination%3B Belongs to the GerABKC lipoprotein family gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02015 BSBS38_02016 BSBS38_02016 BSBS38_02016 1892086 1892892 + putative membrane protein YndG gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02016 BSBS38_02017 BSBS38_02017 BSBS38_02017 1892897 1893529 + uncharacterized protein gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02017 BSBS38_02018 BSBS38_02018 BSBS38_02018 1893511 1895151 + putative membrane protein YndJ gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02018 BSBS38_02019 BSBS38_02019 BSBS38_02019 1895241 1895357 + putative membrane protein YndK gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02019 BSBS38_02020 BSBS38_02020 BSBS38_02020 1895391 1895555 + putative membrane protein YndK gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02020 BSBS38_02021 BSBS38_02021 BSBS38_02021 1895780 1896538 + UPF0714 protein YndL Belongs to the UPF0714 family gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02021 BSBS38_02022 BSBS38_02022 BSBS38_02022 1896565 1897104 - putative membrane protein YndM gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02022 BSBS38_02023 BSBS38_02023 fosB fosB 1897223 1897642 + Metallothiol transferase FosB Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor%3B Belongs to the fosfomycin resistance protein family. FosB subfamily%3B KEGG: bsu:BSU17840 metallothiol transferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02023 BSBS38_02024 BSBS38_02024 BSBS38_02024 1898192 1898809 - Repressor LexA Represses a number of genes involved in the response to DNA damage (SOS response)%2C including recA and lexA. In the presence of single-stranded DNA%2C RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA%2C leading to derepression of the SOS regulon and eventually DNA repair%3B Belongs to the peptidase S24 family%3B KEGG: pae:PA3007 repressor LexA gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02024 BSBS38_02025 BSBS38_02025 BSBS38_02025 1898965 1899276 + Cell division suppressor protein YneA Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly%2C after the assembly of the Z ring%2C by probably suppressing recruitment of FtsL and/or DivIC to the division machinery%3B Belongs to the YneA family gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02025 BSBS38_02026 BSBS38_02026 BSBS38_02026 1899295 1899948 + Resolvase like protein YneB Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02026 BSBS38_02027 BSBS38_02027 BSBS38_02027 1900012 1900245 + 5-formyltetrahydrofolate cyclo-ligase Belongs to the UPF0291 family%3B KEGG: rum:CK1_06990 5-formyltetrahydrofolate cyclo-ligase gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02027 BSBS38_02028 BSBS38_02028 tktA tktA 1900414 1902417 + Transketolase Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor%2C via a covalent intermediate with the cofactor thiamine pyrophosphate%3B Belongs to the transketolase family%3B KEGG: bsu:BSU17890 transketolase gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02028 BSBS38_02029 BSBS38_02029 BSBS38_02029 1902570 1903016 + Sporulation inhibitor of replication protein SirA Inhibits DNA replication in growing cells%2C thus reducing chromosome copy number and playing a significant role during the onset of sporulation gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02029 BSBS38_02030 BSBS38_02030 BSBS38_02030 1903102 1903320 + UPF0154 protein Belongs to the UPF0154 family gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02030 BSBS38_02031 BSBS38_02031 BSBS38_02031 1903394 1903567 - Aspartyl-phosphate phosphatase YnzD Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02031 BSBS38_02032 BSBS38_02032 BSBS38_02032 1903787 1904494 + Cytochrome c-type bioproteinis protein CcdA Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane%2C promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat%3B Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation%3B Belongs to the DsbD family gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02032 BSBS38_02033 BSBS38_02033 BSBS38_02033 1904583 1904945 + Protein CcdB Contains 1 response regulatory domain gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02033 BSBS38_02034 BSBS38_02034 BSBS38_02034 1905033 1905515 + Protein CcdC gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02034 BSBS38_02035 BSBS38_02035 BSBS38_02035 1905546 1905974 - uncharacterized protein gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02035 BSBS38_02036 BSBS38_02036 BSBS38_02036 1906208 1906582 - Spore coat protein gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02036 BSBS38_02037 BSBS38_02037 BSBS38_02037 1906681 1906827 - Small%2C acid-soluble spore protein Belongs to the SspP family gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02037 BSBS38_02038 BSBS38_02038 BSBS38_02038 1906859 1907008 - Small%2C acid-soluble spore protein Belongs to the SspO family gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02038 BSBS38_02039 BSBS38_02039 acnA acnA 1907233 1909962 + Aconitate hydratase Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate (PubMed:3110133). The apo form of AcnA functions as a RNA-binding regulatory protein which plays a role in the regulation of citrate concentration and in the sporulation. To prevent the accumulation of excessive levels of citrate%2C it binds near the 5' end of the citZ mRNA%2C decreasing its stability and thereby limiting the concentration of citrate synthase in the cell. Aconitase also binds to the gerE transcript late in sporulation and stabilizes it for translation%2C thereby increasing the rate and level of GerE protein accumulation (PubMed:9393699%2C PubMed:10468622%2C PubMed:23354745%2C PubMed:16923907). Could catalyze the hydration of 2-methyl-cis- aconitate to yield (2R%2C3S)-2-methylisocitrate (By similarity)%3B Belongs to the aconitase/IPM isomerase family%3B KEGG: bsu:BSU18000 aconitate hydratase gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02039 BSBS38_02040 BSBS38_02040 BSBS38_02040 1910034 1910546 + Thioredoxin-like protein YneN Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02040 BSBS38_02041 BSBS38_02041 BSBS38_02041 1910628 1910753 + uncharacterized protein gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02041 BSBS38_02042 BSBS38_02042 BSBS38_02042 1910818 1910964 + Small%2C acid-soluble spore protein Belongs to the SspN family gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02042 BSBS38_02043 BSBS38_02043 BSBS38_02043 1911001 1911252 + Small%2C acid-soluble spore protein Tlp Belongs to the Tlp family gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02043 BSBS38_02044 BSBS38_02044 ybgC ybgC 1911337 1911753 + Putative acyl-CoA thioesterase YneP Has acyl-CoA thioesterase activity%3B Belongs to the 4-hydroxybenzoyl-CoA thioesterase family%3B KEGG: bsr:I33_2017 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02044 BSBS38_02045 BSBS38_02045 BSBS38_02045 1911769 1912068 + NAD(+) synthase KEGG: ble:BleG1_2142 NAD+ synthase gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02045 BSBS38_02046 BSBS38_02046 BSBS38_02046 1912099 1912386 - uncharacterized protein Belongs to the HesB/IscA family gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02046 BSBS38_02047 BSBS38_02047 plsY plsY 1912474 1913055 - Glycerol-3-phosphate 1-O-acyltransferase Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor%2C but not acyl-CoA or acyl-ACP%3B Belongs to the PlsY family%3B KEGG: dar:Daro_0533 glycerol-3-phosphate acyltransferase PlsY gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02047 BSBS38_02048 BSBS38_02048 BSBS38_02048 1913225 1913632 + uncharacterized protein gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02048 BSBS38_02049 BSBS38_02049 parE parE 1914031 1914609 + DNA topoisomerase 4 subunit Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the type II topoisomerase family. ParE type 2 subfamily%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU18090 topoisomerase IV subunit B%3B Other isomerases gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02049 BSBS38_02050 BSBS38_02050 BSBS38_02050 1914561 1915997 + DNA topoisomerase (ATP-hydrolyzing) Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the type II topoisomerase family. ParE type 2 subfamily%3B Contains 1 Toprim domain%3B KEGG: dav:DESACE_00025 DNA gyrase subunit B gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02050 BSBS38_02051 BSBS38_02051 parC parC 1916001 1918421 + DNA topoisomerase 4 subunit Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily%3B KEGG: bsu:BSU18100 topoisomerase IV subunit A%3B Other isomerases gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02051 BSBS38_02052 BSBS38_02052 BSBS38_02052 1918468 1918593 - hypothetical protein gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02052 BSBS38_02053 BSBS38_02053 BSBS38_02053 1918619 1918972 - uncharacterized protein gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02053 BSBS38_02054 BSBS38_02054 BSBS38_02054 1919482 1920879 + Amino-acid carrier protein AlsT Belongs to the sodium:alanine (SAF) symporter family gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02054 BSBS38_02055 BSBS38_02055 BSBS38_02055 1921182 1922681 + Cellulase Belongs to the glycosyl hydrolase 5 (cellulase A) family%3B Contains 1 CBM3 (carbohydrate binding type-3) domain%3B KEGG: bsu:BSU18130 endoglucanase gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02055 BSBS38_02056 BSBS38_02056 BSBS38_02056 1922748 1923011 + uncharacterized protein gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02056 BSBS38_02057 BSBS38_02057 xynC xynC 1923270 1924538 - Glucuronoarabinoxylan endo-1%2C4-beta-xylanase Catalyzes the depolymerization of methylglucuronoxylan (MeGAXn) from different sources. It cleaves the beta-1%2C4-xylosidic bond penultimate to that linking carbon one of the xylose residue substituted with alpha-1%2C2-linked 4-O-methyl-D-glucuronate (MeGA)%3B Belongs to the glycosyl hydrolase 30 family%3B KEGG: bsu:BSU18150 glucuronoarabinoxylan endo-1%2C4-beta-xylanase gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02057 BSBS38_02058 BSBS38_02058 xynD xynD 1924669 1925964 - Non-reducing end alpha-L-arabinofuranosidase Cleaves arabinose units from O-2- or O-3-monosubstituted xylose residues%2C thereby assisting in arabinoxylan (AX) and short- chain arabinoxylo-oligosaccharide (AXOS) degradation. Is more active on wheat bran AXOS than on wheat water-extractable AX and rye water-extractable AX. Does not display endoxylanase%2C xylosidase or arabinanase activity%3B Belongs to the glycosyl hydrolase 43 family%3B Contains 1 CBM6 (carbohydrate binding type-6) domain%3B KEGG: bsu:BSU18160 arabinoxylan arabinofuranohydrolase%3B overlaps another CDS with the same product name gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02058 BSBS38_02059 BSBS38_02059 BSBS38_02059 1925961 1926224 - Non-reducing end alpha-L-arabinofuranosidase Cleaves arabinose units from O-2- or O-3-monosubstituted xylose residues%2C thereby assisting in arabinoxylan (AX) and short- chain arabinoxylo-oligosaccharide (AXOS) degradation. Is more active on wheat bran AXOS than on wheat water-extractable AX and rye water-extractable AX. Does not display endoxylanase%2C xylosidase or arabinanase activity%3B Belongs to the glycosyl hydrolase 43 family%3B Contains 1 CBM6 (carbohydrate binding type-6) domain%3B KEGG: bsu:BSU18160 arabinoxylan arabinofuranohydrolase%3B overlaps another CDS with the same product name gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02059 BSBS38_02060 BSBS38_02060 BSBS38_02060 1926901 1927347 + putative membrane protein YngA Belongs to the GtrA family gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02060 BSBS38_02061 BSBS38_02061 ugp2 ugp2 1927354 1928247 + UTP--glucose-1-phosphate uridylyltransferase Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG) (By similarity)%3B Belongs to the UDPGP type 2 family%3B KEGG: eca:ECA2329 UTP--glucose-1-phosphate uridylyltransferase gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02061 BSBS38_02062 BSBS38_02062 BSBS38_02062 1928310 1928915 + Alkaline phosphatase Belongs to the DedA family%3B KEGG: llc:LACR_0747 alkaline phosphatase gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02062 BSBS38_02063 BSBS38_02063 BSBS38_02063 1928964 1930163 - Oligoribonuclease NrnB Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02063 BSBS38_02064 BSBS38_02064 pccB pccB 1930333 1931862 - Propionyl-CoA carboxylase Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: bpu:BPUM_2131 propionyl-CoA carboxylase beta chain gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02064 BSBS38_02065 BSBS38_02065 BSBS38_02065 1931879 1932661 - Enoyl-CoA hydratase Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: npa:UCRNP2_3213 enoyl-CoA hydratase gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02065 BSBS38_02066 BSBS38_02066 hmgL hmgL 1932682 1933581 - Hydroxymethylglutaryl-CoA lyase Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate%2C acetoacetate and acetone) are essential as an alternative source of energy to glucose%2C as lipid precursors and as regulators of metabolism%3B Belongs to the HMG-CoA lyase family%3B KEGG: hel:HELO_2935 hydroxymethylglutaryl-CoA lyase gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02066 BSBS38_02067 BSBS38_02067 BSBS38_02067 1933596 1933817 - Biotin/lipoyl attachment protein Contains 1 biotinyl-binding domain gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02067 BSBS38_02068 BSBS38_02068 BSBS38_02068 1933832 1935166 - Urea carboxylase This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: eas:Entas_1995 urea carboxylase gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02068 BSBS38_02069 BSBS38_02069 BSBS38_02069 1935176 1936825 - Putative acyl-CoA synthetase YngI Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU18250 fatty-acyl-CoA synthase%3B Acid--thiol ligases gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02069 BSBS38_02070 BSBS38_02070 BSBS38_02070 1936869 1938011 - Short-chain acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: oih:OB1695 butyryl-CoA dehydrogenase gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02070 BSBS38_02071 BSBS38_02071 BSBS38_02071 1938582 1940114 - N-acetylmuramoyl-L-alanine amidase Belongs to the UPF0748 family%3B KEGG: esr:ES1_16340 N-acetylmuramoyl-L-alanine amidase gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02071 BSBS38_02072 BSBS38_02072 BSBS38_02072 1940250 1940642 - UPF0713 protein YngL Belongs to the UPF0713 family gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02072 BSBS38_02073 BSBS38_02073 BSBS38_02073 1940751 1944569 - Plipastatin synthase subunit This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acid Ile as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The activation sites for this amino acid consist of individual domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 1 acyl carrier domain gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02073 BSBS38_02074 BSBS38_02074 BSBS38_02074 1944598 1952301 - Plipastatin synthase subunit This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Glu and Orn as part of the biosynthesis of the lipopeptide antibiotic lipastatin. The Orn residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 2 acyl carrier domains gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02074 BSBS38_02075 BSBS38_02075 dacB dacB 1952676 1954151 - D-alanyl-D-alanine carboxypeptidase DacC Catalyzes DD-carboxypeptidase and transpeptidation reactions%3B Belongs to the peptidase S13 family%3B KEGG: bsu:BSU18350 D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4)%3B Serine-type D-Ala-D-Ala carboxypeptidase gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02075 BSBS38_02076 BSBS38_02076 galM galM 1954185 1955162 - Aldose 1-epimerase Belongs to the aldose epimerase family%3B KEGG: bsu:BSU18360 aldose 1-epimerase gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02076 BSBS38_02077 BSBS38_02077 BSBS38_02077 1955295 1956686 - putative multidrug resistance protein YoeA Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02077 BSBS38_02078 BSBS38_02078 BSBS38_02078 1956972 1957517 + uncharacterized protein gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02078 BSBS38_02079 BSBS38_02079 BSBS38_02079 1957576 1958376 - putative transposase-like protein Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02079 BSBS38_02080 BSBS38_02080 BSBS38_02080 1958394 1958726 - hypothetical protein gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02080 BSBS38_02081 BSBS38_02081 BSBS38_02081 1958900 1958972 - tRNA-Arg tRNA gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02081 BSBS38_02082 BSBS38_02082 BSBS38_02082 1959025 1959570 - putative integrase/recombinase YoeC Belongs to the 'phage' integrase family gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02082 BSBS38_02083 BSBS38_02083 BSBS38_02083 1959886 1960116 - Glucose-6-phosphate isomerase KEGG: bbe:BBR47_08920 glucose-6-phosphate isomerase gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02083 BSBS38_02084 BSBS38_02084 BSBS38_02084 1960301 1962064 + Gamma-glutamyltransferase Belongs to the gamma-glutamyltransferase family%3B KEGG: bsu:BSU18410 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02084 BSBS38_02085 BSBS38_02085 BSBS38_02085 1962226 1963083 - HTH-type transcriptional regulator YofA Regulates expression of the cell division protein ftsW%2C and is essential for cell viability during stationary phase%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02085 BSBS38_02086 BSBS38_02086 BSBS38_02086 1963211 1964200 + putative zinc-type alcohol dehydrogenase-like protein YogA Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02086 BSBS38_02087 BSBS38_02087 gltD gltD 1964256 1965737 - Glutamate synthase (NADPH) Belongs to the glutamate synthase family%3B KEGG: mca:MCA2040 glutamate synthase (NADPH/NADH) small chain gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02087 BSBS38_02088 BSBS38_02088 gltB gltB 1965754 1970316 - Glutamate synthase (NADPH) Belongs to the glutamate synthase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU18450 glutamate synthase (NADPH/NADH) large chain gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02088 BSBS38_02089 BSBS38_02089 BSBS38_02089 1970463 1971365 + HTH-type transcriptional regulator BsdA Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02089 BSBS38_02090 BSBS38_02090 BSBS38_02090 1971416 1972531 - Glutamate 5-kinase Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: bsu:BSU18470 glutamate 5-kinase gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02090 BSBS38_02091 BSBS38_02091 BSBS38_02091 1972528 1973343 - Pyrroline-5-carboxylate reductase Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU18480 pyrroline-5-carboxylate reductase gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02091 BSBS38_02092 BSBS38_02092 BSBS38_02092 1973569 1973940 - Replication termination protein Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat (By similarity) gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02092 BSBS38_02093 BSBS38_02093 idnO idnO 1974236 1974952 - Gluconate 5-dehydrogenase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: smw:SMWW4_v1c33960 gluconate 5-dehydrogenase gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02093 BSBS38_02094 BSBS38_02094 BSBS38_02094 1975103 1975411 + uncharacterized protein gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02094 BSBS38_02095 BSBS38_02095 BSBS38_02095 1975478 1976248 + uncharacterized protein gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02095 BSBS38_02096 BSBS38_02096 BSBS38_02096 1976292 1976825 + Ribosomal-protein-alanine N-acetyltransferase Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU18530 ribosomal-protein-alanine N-acetyltransferase gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02096 BSBS38_02097 BSBS38_02097 BSBS38_02097 1976967 1977959 - hypothetical protein gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02097 BSBS38_02098 BSBS38_02098 BSBS38_02098 1977953 1978699 - Putative transport permease YfiM Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02098 BSBS38_02099 BSBS38_02099 BSBS38_02099 1978709 1979647 - Nod factor export ATP-binding protein Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors)%2C the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide)%2C a modified beta-1%2C4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Lipooligosaccharide exporter (TC 3. A. 1. 102) family%3B Contains 1 ABC transporter domain gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02099 BSBS38_02100 BSBS38_02100 BSBS38_02100 1979663 1980214 - hypothetical protein gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02100 BSBS38_02101 BSBS38_02101 BSBS38_02101 1980620 1981864 - Alpha-ketoglutarate permease Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. CsbX subfamily gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02101 BSBS38_02102 BSBS38_02102 lsrK lsrK 1981958 1982470 - Putative sugar kinase YoaC Belongs to the FGGY kinase family%3B KEGG: bsr:I33_2078 autoinducer 2 (AI-2) kinase%3B Phosphotransferases with an alcohol group as acceptor gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02102 BSBS38_02103 BSBS38_02103 BSBS38_02103 1982890 1983438 - UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02103 BSBS38_02104 BSBS38_02104 BSBS38_02104 1983686 1985179 - Cardiolipin synthase Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: ban:BA_2054 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02104 BSBS38_02105 BSBS38_02105 BSBS38_02105 1985639 1986877 + Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02105 BSBS38_02106 BSBS38_02106 BSBS38_02106 1987388 1987597 - Putative UV-damage repair protein UvrX Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B overlaps another CDS with the same product name gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02106 BSBS38_02107 BSBS38_02107 BSBS38_02107 1987563 1987844 - Putative UV-damage repair protein UvrX Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B overlaps another CDS with the same product name gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02107 BSBS38_02108 BSBS38_02108 BSBS38_02108 1987871 1988305 - Putative UV-damage repair protein UvrX Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02108 BSBS38_02109 BSBS38_02109 BSBS38_02109 1988464 1988592 - SPBc2 prophage-derived uncharacterized protein YolD gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02109 BSBS38_02110 BSBS38_02110 BSBS38_02110 1988753 1988992 + SPBc2 prophage-derived uncharacterized protein YolC gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02110 BSBS38_02111 BSBS38_02111 BSBS38_02111 1989084 1989443 - SPBc2 prophage-derived uncharacterized protein YolB gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02111 BSBS38_02112 BSBS38_02112 speG speG 1990075 1990608 - Diamine N-acetyltransferase Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bvi:Bcep1808_3304 diamine N-acetyltransferase gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02112 BSBS38_02113 BSBS38_02113 BSBS38_02113 1990668 1991222 - SPBc2 prophage-derived uncharacterized protein YokK gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02113 BSBS38_02114 BSBS38_02114 BSBS38_02114 1991278 1991736 - hypothetical protein gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02114 BSBS38_02115 BSBS38_02115 BSBS38_02115 1991829 1992287 - Antitoxin YobK Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the RNase activity of cognate toxin YobL%2C as well as its ability to inhibit growth upon expression in E. coli. Does not have antitoxin activity on other toxins with the LXG toxin domain gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02115 BSBS38_02116 BSBS38_02116 BSBS38_02116 1992297 1994099 - Ribonuclease YobL Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-600) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YobK%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02116 BSBS38_02117 BSBS38_02117 BSBS38_02117 1994198 1994761 - uncharacterized protein gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02117 BSBS38_02118 BSBS38_02118 aofH aofH 1994883 1996319 + Monoamine oxidase Belongs to the flavin monoamine oxidase family. FIG1 subfamily%3B KEGG: bsut:BSUB_02048 monoamine oxidase gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02118 BSBS38_02119 BSBS38_02119 BSBS38_02119 1996569 1996901 - Protein CsaA Could serves as a molecular chaperone for exported proteins or alternatively acts by stabilizing the SecA protein. Contains 1 tRNA-binding domain gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02119 BSBS38_02120 BSBS38_02120 BSBS38_02120 1996966 1997685 - putative HTH-type transcriptional regulator YobQ Contains 1 HTH araC/xylS-type DNA-binding domain gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02120 BSBS38_02121 BSBS38_02121 BSBS38_02121 1997706 1998449 - Ribosomal-protein-alanine N-acetyltransferase Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: krh:KRH_06670 ribosomal-protein-alanine N-acetyltransferase gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02121 BSBS38_02122 BSBS38_02122 BSBS38_02122 1998527 1999102 - putative HTH-type transcriptional regulator YobS Contains 1 HTH tetR-type DNA-binding domain gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02122 BSBS38_02123 BSBS38_02123 gloB gloB 1999108 1999809 - Hydroxyacylglutathione hydrolase Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: sgo:SGO_1438 hydroxyacylglutathione hydrolase gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02123 BSBS38_02124 BSBS38_02124 BSBS38_02124 1999885 2000367 - Putative transcriptional regulator protein YobU gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02124 BSBS38_02125 BSBS38_02125 BSBS38_02125 2000421 2001359 - putative HTH-type transcriptional regulator YobV Contains 1 HTH deoR-type DNA-binding domain gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02125 BSBS38_02126 BSBS38_02126 BSBS38_02126 2001566 2002111 + Protein csk22 gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02126 BSBS38_02127 BSBS38_02127 BSBS38_02127 2002138 2002461 - HTH-type transcriptional repressor CzrA Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02127 BSBS38_02128 BSBS38_02128 BSBS38_02128 2002656 2003333 + putative membrane protein YocA gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02128 BSBS38_02129 BSBS38_02129 BSBS38_02129 2003423 2003959 - putative membrane protein YozB gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02129 BSBS38_02130 BSBS38_02130 BSBS38_02130 2004096 2004878 - uncharacterized protein gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02130 BSBS38_02131 BSBS38_02131 BSBS38_02131 2005049 2005546 + uncharacterized protein gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02131 BSBS38_02132 BSBS38_02132 BSBS38_02132 2005610 2006587 + Muramoyltetrapeptide carboxypeptidase Belongs to the peptidase S66 family%3B KEGG: lmf:LMOf2365_1660 muramoyltetrapeptide carboxypeptidase gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02132 BSBS38_02133 BSBS38_02133 fad6 fad6 2006749 2007807 + Fatty acid desaturase Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids%3B Belongs to the fatty acid desaturase family%3B KEGG: bsu:BSU19180 omega-6 fatty acid desaturase (delta-12 desaturase)%3B With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02133 BSBS38_02134 BSBS38_02134 BSBS38_02134 2007927 2009039 + Histidine kinase Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsr:I33_2153 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02134 BSBS38_02135 BSBS38_02135 BSBS38_02135 2009058 2009657 + Transcriptional regulatory protein DesR Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02135 BSBS38_02136 BSBS38_02136 BSBS38_02136 2009570 2009749 - hypothetical protein gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02136 BSBS38_02137 BSBS38_02137 BSBS38_02137 2010265 2011128 - Cell wall-binding protein YocH Contains 2 LysM repeats%3B KEGG: gwc:GWCH70_1211 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02137 BSBS38_02138 BSBS38_02138 recQ recQ 2011376 2013151 - DNA helicase Probable DNA helicase. Required for DNA repair and intramolecular recombinatio%3B probably has overlapping function with RecS (AC P50729). It probably acts to help generate ss-DNA from ds-DNA breaks%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 HRDC domain%3B KEGG: bsu:BSU19220 ATP-dependent DNA helicase RecQ gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02138 BSBS38_02139 BSBS38_02139 acpD acpD 2013711 2014337 - FMN-dependent NADH-azoreductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity. Confers resistance to catechol%2C 2-methylhydroquinone (2-MHQ)%2C and diamide. Probably could also reduce benzoquinones produce by the auto-oxidation of catechol and 2-methylhydroquinone%3B Belongs to the azoreductase type 1 family%3B KEGG: bsu:BSU19230 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02139 BSBS38_02140 BSBS38_02140 BSBS38_02140 2014489 2014980 - General stress protein 16O Contains 1 dksA C4-type zinc finger gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02140 BSBS38_02141 BSBS38_02141 BSBS38_02141 2015055 2015387 - uncharacterized protein gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02141 BSBS38_02142 BSBS38_02142 BSBS38_02142 2015465 2015692 + uncharacterized protein gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02142 BSBS38_02143 BSBS38_02143 BSBS38_02143 2015679 2016155 - uncharacterized protein Belongs to the small heat shock protein (HSP20) family gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02143 BSBS38_02144 BSBS38_02144 BSBS38_02144 2016222 2016485 + uncharacterized protein gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02144 BSBS38_02145 BSBS38_02145 BSBS38_02145 2016490 2016723 + uncharacterized protein gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02145 BSBS38_02146 BSBS38_02146 BSBS38_02146 2016817 2017161 - uncharacterized protein gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02146 BSBS38_02147 BSBS38_02147 BSBS38_02147 2017517 2017720 - uncharacterized protein gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02147 BSBS38_02148 BSBS38_02148 BSBS38_02148 2017950 2019437 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU19310 aldehyde dehydrogenase (NAD+) gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02148 BSBS38_02149 BSBS38_02149 sqhC sqhC 2019538 2021436 + Sporulenol synthase Catalyzes the cyclization of tetraprenyl beta-curcumene into sporulenol%3B Belongs to the terpene cyclase/mutase family%3B Contains 3 PFTB repeats%3B KEGG: bsu:BSU19320 sporulenol synthase gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02149 BSBS38_02150 BSBS38_02150 sod2 sod2 2021426 2022262 + Superoxide dismutase Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bsr:I33_2171 superoxide dismutase%2C Fe-Mn family gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02150 BSBS38_02151 BSBS38_02151 BSBS38_02151 2022294 2023631 - putative sodium-dependent transporter YocR Putative sodium-dependent transporter%3B Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02151 BSBS38_02152 BSBS38_02152 BSBS38_02152 2023850 2024815 + putative sodium-dependent transporter YocS Belongs to the bile acid:sodium symporter (BASS) (TC 2. A. 28) family gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02152 BSBS38_02153 BSBS38_02153 BSBS38_02153 2024865 2026118 - Dihydrolipoyllysine-residue succinyltransferase The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: cvi:CV_1072 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02153 BSBS38_02154 BSBS38_02154 ogdH ogdH 2026133 2028967 - Oxoglutarate dehydrogenase (succinyl-transferring) The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)%3B Belongs to the alpha-ketoglutarate dehydrogenase family%3B KEGG: bsu:BSU19370 2-oxoglutarate dehydrogenase E1 component gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02154 BSBS38_02155 BSBS38_02155 BSBS38_02155 2029196 2031112 - uncharacterized protein Contains 1 VWFA domain gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02155 BSBS38_02156 BSBS38_02156 BSBS38_02156 2031123 2032013 - uncharacterized protein Belongs to the CbbQ/NirQ/NorQ/GpvN family gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02156 BSBS38_02157 BSBS38_02157 sod1 sod1 2032101 2032691 - Superoxide dismutase Belongs to the Cu-Zn superoxide dismutase family%3B KEGG: bsu:BSU19400 superoxide dismutase%2C Cu-Zn family gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02157 BSBS38_02158 BSBS38_02158 BSBS38_02158 2032784 2034028 - D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS Probably functions as a cell separation enzyme in addition to LytE and LytF%3B Belongs to the peptidase C40 family%3B Contains 4 LysM repeats%3B KEGG: bsu:BSU09370 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02158 BSBS38_02159 BSBS38_02159 BSBS38_02159 2034399 2035616 - putative UDP-glucosyltransferase YojK Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02159 BSBS38_02160 BSBS38_02160 BSBS38_02160 2035852 2036466 - Diadenylate cyclase KEGG: tth:TTC1660 diadenylate cyclase gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02160 BSBS38_02161 BSBS38_02161 BSBS38_02161 2036555 2036665 + hypothetical protein gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02161 BSBS38_02162 BSBS38_02162 BSBS38_02162 2036741 2038099 + putative multidrug resistance protein NorM Multidrug efflux pump%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02162 BSBS38_02163 BSBS38_02163 BSBS38_02163 2038115 2038963 + RsbT co-antagonist protein RsbRC One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02163 BSBS38_02164 BSBS38_02164 BSBS38_02164 2038989 2039654 - putative N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal)%3B Belongs to the PIGL family gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02164 BSBS38_02165 BSBS38_02165 BSBS38_02165 2039674 2040024 - uncharacterized protein overlaps another CDS with the same product name gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02165 BSBS38_02166 BSBS38_02166 BSBS38_02166 2040021 2040299 - uncharacterized protein overlaps another CDS with the same product name gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02166 BSBS38_02167 BSBS38_02167 BSBS38_02167 2040375 2041271 - putative transporter YojE Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02167 BSBS38_02168 BSBS38_02168 BSBS38_02168 2041370 2041843 + Spore germination protein GerT Involved in spore germinatio%3B probably required at the earliest stage of germination gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02168 BSBS38_02169 BSBS38_02169 BSBS38_02169 2041878 2042114 - uncharacterized protein gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02169 BSBS38_02170 BSBS38_02170 BSBS38_02170 2042199 2042975 - putative permease YojA Belongs to the GntP permease family gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02170 BSBS38_02171 BSBS38_02171 BSBS38_02171 2042972 2043532 - Gluconate permease Belongs to the GntP permease family gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02171 BSBS38_02172 BSBS38_02172 praC praC 2043898 2044287 + 2-hydroxymuconate tautomerase Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: mav:MAV_2790 4-oxalocrotonate tautomerase gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02172 BSBS38_02173 BSBS38_02173 BSBS38_02173 2044694 2045020 - HTH-type transcriptional regulator YodB Negatively regulates yodC and azoR1 which may contribute to the degradation of aromatic compounds. Probably positively regulates the catechol-specific transcription of mhqNOP%2C mhqED%2C and mhqA%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02173 BSBS38_02174 BSBS38_02174 BSBS38_02174 2045162 2045770 + Putative NAD(P)H nitroreductase YodC Putative nitroreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the nitroreductase family%3B KEGG: baci:B1NLA3E_00805 putative NAD(P)H nitroreductase%3B Oxidoreductases gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02174 BSBS38_02175 BSBS38_02175 BSBS38_02175 2045890 2046222 + hypothetical protein gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02175 BSBS38_02176 BSBS38_02176 BSBS38_02176 2046240 2047040 + putative transposase-like protein Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02176 BSBS38_02177 BSBS38_02177 BSBS38_02177 2047103 2047705 - Putative hydrolase Putative hydrolase that may contribute to the degradation of aromatic compounds%3B Belongs to the AB hydrolase superfamily. AB hydrolase 2 family gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02177 BSBS38_02178 BSBS38_02178 BSBS38_02178 2047721 2048632 - Putative ring-cleaving dioxygenase MhqE Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02178 BSBS38_02179 BSBS38_02179 BSBS38_02179 2048816 2049016 + putative membrane protein YoyD gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02179 BSBS38_02180 BSBS38_02180 BSBS38_02180 2049016 2050506 + putative symporter YodF Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02180 BSBS38_02181 BSBS38_02181 ctpA ctpA 2050540 2051940 - C-terminal processing peptidase Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bsu:BSU19590 carboxyl-terminal processing protease gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02181 BSBS38_02182 BSBS38_02182 BSBS38_02182 2052093 2052794 + putative methyltransferase YodH Belongs to the methyltransferase superfamily gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02182 BSBS38_02183 BSBS38_02183 BSBS38_02183 2052882 2053133 + uncharacterized protein gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02183 BSBS38_02184 BSBS38_02184 vanY vanY 2053204 2054025 - Serine-type D-Ala-D-Ala carboxypeptidase Belongs to the peptidase M15B family%3B KEGG: bsu:BSU19620 D-alanyl-D-alanine carboxypeptidase gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02184 BSBS38_02185 BSBS38_02185 deoD deoD 2054108 2054809 - Purine-nucleoside phosphorylase Belongs to the PNP/UDP phosphorylase family%3B KEGG: shp:Sput200_1676 purine-nucleoside phosphorylase gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02185 BSBS38_02186 BSBS38_02186 BSBS38_02186 2055011 2055136 + uncharacterized protein gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02186 BSBS38_02187 BSBS38_02187 BSBS38_02187 2055176 2055490 - uncharacterized protein gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02187 BSBS38_02188 BSBS38_02188 bcrC bcrC 2055551 2056162 - Undecaprenyl-diphosphate phosphatase Belongs to the PA-phosphatase related phosphoesterase family%3B KEGG: bss:BSUW23_10505 undecaprenyl-diphosphatase gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02188 BSBS38_02189 BSBS38_02189 BSBS38_02189 2056239 2056415 - uncharacterized protein gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02189 BSBS38_02190 BSBS38_02190 BSBS38_02190 2056534 2056677 + putative membrane protein YoyF gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02190 BSBS38_02191 BSBS38_02191 BSBS38_02191 2056674 2057354 - uncharacterized protein gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02191 BSBS38_02192 BSBS38_02192 BSBS38_02192 2057502 2057726 - UPF0346 protein Belongs to the UPF0346 family gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02192 BSBS38_02193 BSBS38_02193 BSBS38_02193 2057813 2058091 - uncharacterized protein gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02193 BSBS38_02194 BSBS38_02194 kamA kamA 2058088 2059503 - Lysine 2%2C3-aminomutase Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine%3B Belongs to the radical SAM superfamily. KamA family%3B KEGG: bsu:BSU19690 lysine 2%2C3-aminomutase gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02194 BSBS38_02195 BSBS38_02195 BSBS38_02195 2059532 2060359 - Lysine 2%2C3-aminomutase In vitro%2C is able to catalyze the acetylation of beta- lysine to N6-acetyl-beta-lysine%2C an archaeal osmolyte produced by methanogenic archaea. Its physiological function has not yet been elucidated%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: ipo:Ilyop_2505 lysine 2%2C3-aminomutase gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02195 BSBS38_02196 BSBS38_02196 BSBS38_02196 2060337 2061641 - Acetylornithine deacetylase Belongs to the peptidase M20A family%3B KEGG: bsu:BSU19710 acetylornithine deacetylase gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02196 BSBS38_02197 BSBS38_02197 scoB scoB 2061656 2062309 - 3-oxoacid CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit B family%3B KEGG: samy:DB32_004337 3-oxoacid CoA-transferase subunit B gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02197 BSBS38_02198 BSBS38_02198 atoD atoD 2062294 2062983 - Acetate CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit A family%3B KEGG: bsr:I33_2216 acetate CoA/acetoacetate CoA-transferase alpha subunit gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02198 BSBS38_02199 BSBS38_02199 BSBS38_02199 2062990 2064324 - Beta-alanine--pyruvate transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: pfv:Psefu_3751 beta-alanine--pyruvate transaminase gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02199 BSBS38_02200 BSBS38_02200 BSBS38_02200 2064305 2064460 - hypothetical protein gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02200 BSBS38_02201 BSBS38_02201 BSBS38_02201 2064647 2065426 - putative N-acetyltransferase CgeE May be involved in maturation of the outermost layer of the spore. Contains 1 N-acetyltransferase domain gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02201 BSBS38_02202 BSBS38_02202 BSBS38_02202 2065455 2066735 - Protein CgeD May be involved in maturation of the outermost layer of the spore. To B. subtilis spore coat polysaccharide biosynthesis protein SpsA gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02202 BSBS38_02203 BSBS38_02203 BSBS38_02203 2066800 2067105 - Protein CgeC gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02203 BSBS38_02204 BSBS38_02204 BSBS38_02204 2067310 2067711 + Protein CgeA gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02204 BSBS38_02205 BSBS38_02205 BSBS38_02205 2067718 2068671 + Protein CgeB gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02205 BSBS38_02206 BSBS38_02206 BSBS38_02206 2068742 2069890 - 3-phytase Contains 1 BPP (beta-propeller phytase) domain%3B KEGG: bsr:I33_2224 3-phytase gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02206 BSBS38_02207 BSBS38_02207 capD capD 2070261 2071277 + UDP-glucose 4-epimerase Belongs to the polysaccharide synthase family%3B KEGG: bsh:BSU6051_19810 UDP-glucose 4-epimerase gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02207 BSBS38_02208 BSBS38_02208 msrB msrB 2071321 2071755 - Peptide-methionine (R)-S-oxide reductase Belongs to the MsrB Met sulfoxide reductase family%3B KEGG: bsu:BSU21680 peptide-methionine (R)-S-oxide reductase gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02208 BSBS38_02209 BSBS38_02209 msrA msrA 2071756 2072289 - Peptide-methionine (S)-S-oxide reductase Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine%3B Belongs to the MsrA Met sulfoxide reductase family%3B KEGG: bsu:BSU21690 peptide-methionine (S)-S-oxide reductase gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02209 BSBS38_02210 BSBS38_02210 BSBS38_02210 2072421 2072846 + putative HTH-type transcriptional regulator YpoP Contains 1 HTH marR-type DNA-binding domain gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02210 BSBS38_02211 BSBS38_02211 BSBS38_02211 2072896 2074233 - putative multidrug resistance protein YpnP Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02211 BSBS38_02212 BSBS38_02212 BSBS38_02212 2074305 2074499 - uncharacterized protein gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02212 BSBS38_02213 BSBS38_02213 BSBS38_02213 2074512 2075075 - uncharacterized protein gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02213 BSBS38_02214 BSBS38_02214 BSBS38_02214 2075085 2075852 - uncharacterized protein gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02214 BSBS38_02215 BSBS38_02215 BSBS38_02215 2075891 2076511 - SCO1 protein like protein Neccessary for insertion of copper into the active site of cytochrome c oxidase. May play a role in copper homeostasis or redox signaling%3B Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02215 BSBS38_02216 BSBS38_02216 BSBS38_02216 2076659 2076910 - uncharacterized protein gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02216 BSBS38_02217 BSBS38_02217 ilvA ilvA 2076996 2078264 - Threonine ammonia-lyase Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: bsu:BSU21770 threonine dehydratase gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02217 BSBS38_02218 BSBS38_02218 BSBS38_02218 2078513 2079472 + Putative sigma L-dependent transcriptional regulator YplP Contains 1 sigma-54 factor interaction domain gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02218 BSBS38_02219 BSBS38_02219 BSBS38_02219 2079528 2080169 + Hemolysin-3 like protein Belongs to the UPF0073 (Hly-III) family gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02219 BSBS38_02220 BSBS38_02220 BSBS38_02220 2080209 2080829 - 1-acylglycerol-3-phosphate O-acyltransferase KEGG: bss:BSUW23_10665 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02220 BSBS38_02221 BSBS38_02221 folA folA 2080781 2081335 - Dihydrofolate reductase Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis%2C and for DNA precursor synthesis (By similarity)%3B Belongs to the dihydrofolate reductase family%3B Contains 1 DHFR (dihydrofolate reductase) domain%3B KEGG: noc:Noc_0235 dihydrofolate reductase gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02221 BSBS38_02222 BSBS38_02222 pgpA pgpA 2081478 2082011 - Phosphatidylglycerophosphatase To B. subtilis YutG%3B KEGG: bpu:BPUM_1917 phosphatidylglycerophosphatase A gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02222 BSBS38_02223 BSBS38_02223 BSBS38_02223 2082029 2082640 - uncharacterized protein gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02223 BSBS38_02224 BSBS38_02224 BSBS38_02224 2082900 2083673 - uncharacterized protein gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02224 BSBS38_02225 BSBS38_02225 BSBS38_02225 2083715 2084149 - UPF0403 protein Belongs to the UPF0403 family gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02225 BSBS38_02226 BSBS38_02226 ilvD ilvD 2084257 2085933 - Dihydroxy-acid dehydratase Belongs to the IlvD/Edd family%3B KEGG: bsu:BSU21870 dihydroxy-acid dehydratase gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02226 BSBS38_02227 BSBS38_02227 BSBS38_02227 2086222 2087355 - uncharacterized protein gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02227 BSBS38_02228 BSBS38_02228 BSBS38_02228 2087415 2088032 - uncharacterized protein Contains 1 HD domain gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02228 BSBS38_02229 BSBS38_02229 BSBS38_02229 2088048 2088530 - Glutathione peroxidase Belongs to the glutathione peroxidase family%3B KEGG: bsu:BSU21900 glutathione peroxidase gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02229 BSBS38_02230 BSBS38_02230 metA metA 2088872 2089777 + Homoserine O-succinyltransferase Belongs to the HTS family%3B KEGG: bsu:BSU21910 homoserine O-succinyltransferase gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02230 BSBS38_02231 BSBS38_02231 BSBS38_02231 2090008 2091156 + 1%2C2-diacylglycerol 3-glucosyltransferase Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG)%2C thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1%2C2-diacyl- sn-glycerol)%2C beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)%3B Belongs to the glycosyltransferase 28 family. UgtP subfamily%3B KEGG: bsu:BSU21920 processive 1%2C2-diacylglycerol beta-glucosyltransferase gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02231 BSBS38_02232 BSBS38_02232 BSBS38_02232 2091398 2091598 + Cold shock protein CspB Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02232 BSBS38_02233 BSBS38_02233 BSBS38_02233 2091650 2091832 - Regulatory protein DegR Stabilizes the phosphorylated form of DegU%2C leading to enhanced production of levansucrase%2C alkaline protease%2C and neutral protease gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02233 BSBS38_02234 BSBS38_02234 BSBS38_02234 2091988 2092257 + uncharacterized protein gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02234 BSBS38_02235 BSBS38_02235 BSBS38_02235 2092285 2092455 - uncharacterized protein gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02235 BSBS38_02236 BSBS38_02236 rnhA rnhA 2092460 2093140 - Ribonuclease H Contains 1 RNase H domain%3B KEGG: bsu:BSU21970 ribonuclease HI gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02236 BSBS38_02237 BSBS38_02237 BSBS38_02237 2093223 2093912 + uncharacterized protein gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02237 BSBS38_02238 BSBS38_02238 BSBS38_02238 2093912 2094310 + Ribonuclease H Not know%3B does not have RNase H activity. Belongs to the RNase H family. EbsB subfamily%3B Contains 1 RNase H domain%3B KEGG: bsu:BSU21990 ribonuclease HI gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02238 BSBS38_02239 BSBS38_02239 BSBS38_02239 2094352 2094480 + Small%2C acid-soluble spore protein gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02239 BSBS38_02240 BSBS38_02240 dpo1 dpo1 2094488 2095378 - DNA-directed DNA polymerase 5'-3' exonuclease acting preferentially on double- stranded DNA%3B Contains 1 5'-3' exonuclease domain%3B KEGG: lhe:lhv_1617 DNA polymerase I gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02240 BSBS38_02241 BSBS38_02241 BSBS38_02241 2095479 2095625 - uncharacterized protein gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02241 BSBS38_02242 BSBS38_02242 BSBS38_02242 2095700 2095957 - uncharacterized protein gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02242 BSBS38_02243 BSBS38_02243 BSBS38_02243 2096022 2099603 - uncharacterized protein gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02243 BSBS38_02244 BSBS38_02244 BSBS38_02244 2099939 2100445 - uncharacterized protein gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02244 BSBS38_02245 BSBS38_02245 BSBS38_02245 2100449 2101546 - Putative chalcone synthase Belongs to the chalcone/stilbene synthases family gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02245 BSBS38_02246 BSBS38_02246 BSBS38_02246 2101619 2102935 - Xanthine permease Transport of xanthine in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02246 BSBS38_02247 BSBS38_02247 BSBS38_02247 2102932 2103516 - Xanthine phosphoribosyltransferase Converts the preformed base xanthine%2C a product of nucleic acid breakdown%2C to xanthosine 5'-monophosphate (XMP)%2C so it can be reused for RNA or DNA synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily%3B KEGG: pre:PCA10_55060 xanthine phosphoribosyltransferase gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02247 BSBS38_02248 BSBS38_02248 BSBS38_02248 2103848 2105353 - Carboxypeptidase Taq Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus%2C including neutral%2C aromatic%2C polar and basic residues. Has lower activity with substrates ending with His or Trp%3B Belongs to the peptidase M32 family%3B KEGG: bsu:BSU22080 carboxypeptidase Taq gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02248 BSBS38_02249 BSBS38_02249 BSBS38_02249 2105465 2106457 - 2-keto-3-deoxygluconate permease The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell%2C where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)%3B Belongs to the KdgT transporter family gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02249 BSBS38_02250 BSBS38_02250 BSBS38_02250 2106502 2107092 - 2-dehydro-3-deoxy-phosphogluconate aldolase Belongs to the KHG/KDPG aldolase family%3B KEGG: bsu:BSU22100 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02250 BSBS38_02251 BSBS38_02251 kdgK kdgK 2107094 2108068 - 2-dehydro-3-deoxygluconokinase Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG)%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU22110 2-dehydro-3-deoxygluconokinase gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02251 BSBS38_02252 BSBS38_02252 BSBS38_02252 2108106 2109125 - HTH-type transcriptional regulator KdgR Transcriptional repressor of the kdgRKAT and kduID operons for pectin utilization%3B Contains 1 HTH lacI-type DNA-binding domain gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02252 BSBS38_02253 BSBS38_02253 kduI kduI 2109347 2110174 + 5-dehydro-4-deoxy-D-glucuronate isomerase Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2%2C5-hexodiulosonate%3B Belongs to the KduI family%3B KEGG: cja:CJA_0169 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02253 BSBS38_02254 BSBS38_02254 kduD kduD 2110176 2110940 + 2-deoxy-D-gluconate 3-dehydrogenase Catalyzes the reduction of 2%2C5-diketo-3-deoxygluconate (DKII or 4%2C6-dihydroxy-2%2C5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bso:BSNT_03298 2-deoxy-D-gluconate 3-dehydrogenase gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02254 BSBS38_02255 BSBS38_02255 dinG dinG 2110981 2112906 - DNA helicase Belongs to the helicase family. DinG subfamily%3B Contains 1 helicase ATP-binding domain%3B KEGG: bsu:BSU22150 ATP-dependent DNA helicase DinG gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02255 BSBS38_02256 BSBS38_02256 BSBS38_02256 2113009 2113200 - uncharacterized protein gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02256 BSBS38_02257 BSBS38_02257 ypsC ypsC 2113569 2114726 - Putative RNA methyltransferase YpsC Belongs to the methyltransferase superfamily%3B Contains 1 THUMP domain%3B KEGG: bsu:BSU22170 putative N6-adenine-specific DNA methylase%3B Methyltransferases gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02257 BSBS38_02258 BSBS38_02258 BSBS38_02258 2115273 2115569 - Cell cycle protein GpsB Divisome component that associates with the complex late in its assembly%2C after the Z-ring is formed%2C and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA%2C is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation%3B Belongs to the GpsB family gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02258 BSBS38_02259 BSBS38_02259 BSBS38_02259 2115645 2116190 - UPF0398 protein Belongs to the UPF0398 family gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02259 BSBS38_02260 BSBS38_02260 BSBS38_02260 2116818 2118059 - uncharacterized protein gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02260 BSBS38_02261 BSBS38_02261 BSBS38_02261 2118075 2120324 - putative ATP-dependent helicase YprA Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02261 BSBS38_02262 BSBS38_02262 BSBS38_02262 2120427 2120984 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane%3B Contains 1 PTS EIIA type-1 domain%3B KEGG: bso:BSNT_03311 PTS system%2C glucose-specific IIA component gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02262 BSBS38_02263 BSBS38_02263 BSBS38_02263 2121071 2121490 + uncharacterized protein gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02263 BSBS38_02264 BSBS38_02264 BSBS38_02264 2121511 2121888 - uncharacterized protein gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02264 BSBS38_02265 BSBS38_02265 BSBS38_02265 2122076 2122264 + uncharacterized protein gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02265 BSBS38_02266 BSBS38_02266 BSBS38_02266 2122303 2122674 - uncharacterized protein gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02266 BSBS38_02267 BSBS38_02267 BSBS38_02267 2122720 2122965 - uncharacterized protein gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02267 BSBS38_02268 BSBS38_02268 BSBS38_02268 2123164 2123268 + Small%2C acid-soluble spore protein gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02268 BSBS38_02269 BSBS38_02269 BSBS38_02269 2123293 2124255 - uncharacterized protein gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02269 BSBS38_02270 BSBS38_02270 BSBS38_02270 2124296 2124916 + Holliday junction resolvase RecU Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands%3B Belongs to the RecU family gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02270 BSBS38_02271 BSBS38_02271 mrcA mrcA 2124938 2127682 + Penicillin-binding protein 1A/1B Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity)%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B Contains 1 fibronectin type-III domain%3B KEGG: bsu:BSU22320 penicillin-binding protein 1A%3B Hexosyltransferases gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02271 BSBS38_02272 BSBS38_02272 BSBS38_02272 2127758 2128252 - uncharacterized protein gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02272 BSBS38_02273 BSBS38_02273 BSBS38_02273 2128249 2128908 - DNA-(apurinic or apyrimidinic site) lyase DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond%2C leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination%2C leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: bsu:BSU22340 endonuclease III gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02273 BSBS38_02274 BSBS38_02274 BSBS38_02274 2128927 2129625 - DNA replication protein DnaD gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02274 BSBS38_02275 BSBS38_02275 narS narS 2129718 2131013 - Asparagine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsl:A7A1_2925 asparaginyl-tRNA synthetase gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02275 BSBS38_02276 BSBS38_02276 aspB aspB 2131154 2132335 - Aspartate transaminase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: woo:wOo_04400 aspartate aminotransferase gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02276 BSBS38_02277 BSBS38_02277 BSBS38_02277 2132358 2132843 - uncharacterized protein gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02277 BSBS38_02278 BSBS38_02278 BSBS38_02278 2132852 2133022 - uncharacterized protein gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02278 BSBS38_02279 BSBS38_02279 BSBS38_02279 2133165 2135960 - DNA helicase Probable helicase involved in DNA repair and perhaps also replication%3B Belongs to the helicase family. DinG subfamily%3B Contains 1 exonuclease domain%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU22400 ATP-dependent DNA helicase DinG gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02279 BSBS38_02280 BSBS38_02280 panD panD 2136086 2136469 - Aspartate 1-decarboxylase Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine%3B Belongs to the PanD family%3B KEGG: pin:Ping_0578 aspartate 1-decarboxylase gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02280 BSBS38_02281 BSBS38_02281 panC panC 2136471 2137331 - Pantoate--beta-alanine ligase (AMP-forming) Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate%3B Belongs to the pantothenate synthetase family%3B KEGG: bsu:BSU22420 pantoate--beta-alanine ligase gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02281 BSBS38_02282 BSBS38_02282 panB panB 2137333 2138166 - 3-methyl-2-oxobutanoate hydroxymethyltransferase Catalyzes the reversible reaction in which hydroxymethyl group from 5%2C10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate%3B Belongs to the PanB family%3B KEGG: bsu:BSU22430 3-methyl-2-oxobutanoate hydroxymethyltransferase gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02282 BSBS38_02283 BSBS38_02283 birA birA 2138411 2139388 - Biotin--[acetyl-CoA-carboxylase] ligase Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor%3B Belongs to the biotin--protein ligase family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU22440 BirA family transcriptional regulator%2C biotin operon repressor / biotin-(acetyl-CoA-carboxylase) ligase gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02283 BSBS38_02284 BSBS38_02284 BSBS38_02284 2139373 2140566 - CCA-adding enzyme Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C%2C C%2C and A to the tRNA nucleotide-73%2C using CTP and ATP as substrates and producing inorganic pyrophosphate. Has no poly(A) polymerase activity%3B Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily%3B KEGG: bsu:BSU22450 tRNA nucleotidyltransferase (CCA-adding enzyme)%3B CCA tRNA nucleotidyltransferase gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02284 BSBS38_02285 BSBS38_02285 BSBS38_02285 2140571 2141704 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: saa:SAUSA300_1349 null%3B Hexosyltransferases gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02285 BSBS38_02286 BSBS38_02286 BSBS38_02286 2141701 2142411 - N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal)%3B Belongs to the PIGL family gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02286 BSBS38_02287 BSBS38_02287 mgsA mgsA 2142404 2142817 - Methylglyoxal synthase Belongs to the methylglyoxal synthase family%3B KEGG: amc:MADE_1002670 methylglyoxal synthase gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02287 BSBS38_02288 BSBS38_02288 dapB dapB 2142833 2143636 - 4-hydroxy-tetrahydrodipicolinate reductase Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate%3B Belongs to the DapB family%3B KEGG: bsu:BSU22490 4-hydroxy-tetrahydrodipicolinate reductase gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02288 BSBS38_02289 BSBS38_02289 aroA aroA 2143648 2143983 - 3-phosphoshikimate 1-carboxyvinyltransferase KEGG: eao:BD94_0226 3-phosphoshikimate 1-carboxyvinyltransferase gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02289 BSBS38_02290 BSBS38_02290 BSBS38_02290 2144123 2144995 + UPF0750 membrane protein YpjC Belongs to the UPF0750 family gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02290 BSBS38_02291 BSBS38_02291 BSBS38_02291 2145037 2145831 - uncharacterized protein gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02291 BSBS38_02292 BSBS38_02292 BSBS38_02292 2145900 2146493 - uncharacterized protein gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02292 BSBS38_02293 BSBS38_02293 BSBS38_02293 2146604 2147371 - Menaquinol-cytochrome c reductase cytochrome b/c subunit Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family%3B Contains 1 cytochrome c domain gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02293 BSBS38_02294 BSBS38_02294 BSBS38_02294 2147406 2148080 - Menaquinol-cytochrome c reductase cytochrome b subunit Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02294 BSBS38_02295 BSBS38_02295 qcrA qcrA 2148082 2148585 - Menaquinol-cytochrome c reductase iron-sulfur subunit Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. Contains 1 Rieske domain%3B KEGG: bsu:BSU22560 menaquinol-cytochrome c reductase iron-sulfur subunit%3B With a cytochrome as acceptor gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02295 BSBS38_02296 BSBS38_02296 BSBS38_02296 2148728 2149174 - uncharacterized protein gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02296 BSBS38_02297 BSBS38_02297 BSBS38_02297 2149229 2149768 - UPF0302 protein Belongs to the UPF0302 family gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02297 BSBS38_02298 BSBS38_02298 BSBS38_02298 2149840 2151111 - TPR repeat-containing protein YpiA Contains 9 TPR repeats gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02298 BSBS38_02299 BSBS38_02299 BSBS38_02299 2151446 2152732 - 3-phosphoshikimate 1-carboxyvinyltransferase Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate%3B Belongs to the EPSP synthase family%3B KEGG: bsr:I33_2320 3-phosphoshikimate 1-carboxyvinyltransferase gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02299 BSBS38_02300 BSBS38_02300 BSBS38_02300 2152743 2153858 - Prephenate dehydrogenase Contains 1 ACT domain%3B Contains 1 prephenate/arogenate dehydrogenase domain%3B KEGG: bsu:BSU22610 prephenate dehydrogenase gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02300 BSBS38_02301 BSBS38_02301 hisC hisC 2153907 2154989 - Histidinol-phosphate transaminase Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily%3B KEGG: bsu:BSU22620 histidinol-phosphate aminotransferase gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02301 BSBS38_02302 BSBS38_02302 trpA trpA 2155000 2155803 - Tryptophan synthase The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate%3B Belongs to the TrpA family%3B KEGG: bsu:BSU22630 tryptophan synthase alpha chain%3B overlaps another CDS with the same product name gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02302 BSBS38_02303 BSBS38_02303 trpB trpB 2155796 2156998 - Tryptophan synthase The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine%3B Belongs to the TrpB family%3B KEGG: bsu:BSU22640 tryptophan synthase beta chain%3B overlaps another CDS with the same product name gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02303 BSBS38_02304 BSBS38_02304 BSBS38_02304 2156979 2157626 - Phosphoribosylanthranilate isomerase Belongs to the TrpF family%3B KEGG: bsu:BSU22650 phosphoribosylanthranilate isomerase gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02304 BSBS38_02305 BSBS38_02305 trpC trpC 2157631 2158383 - Indole-3-glycerol-phosphate synthase Belongs to the TrpC family%3B KEGG: bsu:BSU22660 indole-3-glycerol phosphate synthase gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02305 BSBS38_02306 BSBS38_02306 trpD trpD 2158376 2159392 - Anthranilate phosphoribosyltransferase Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: bsu:BSU22670 anthranilate phosphoribosyltransferase gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02306 BSBS38_02307 BSBS38_02307 trpE trpE 2159364 2160911 - Anthranilate synthase Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate%2C an intermediate in the biosynthesis of L-tryptophan. In the first step%2C the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG%2C TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)%3B Belongs to the anthranilate synthase component I family%3B KEGG: bsu:BSU22680 anthranilate synthase component I gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02307 BSBS38_02308 BSBS38_02308 aroH aroH 2161127 2161510 - Chorismate mutase Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis%3B Contains 1 chorismate mutase aroH-type domain%3B KEGG: bsu:BSU22690 chorismate mutase gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02308 BSBS38_02309 BSBS38_02309 aroB aroB 2161507 2162595 - 3-dehydroquinate synthase Belongs to the dehydroquinate synthase family%3B KEGG: bsu:BSU22700 3-dehydroquinate synthase gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02309 BSBS38_02310 BSBS38_02310 aroC aroC 2162595 2163623 - Chorismate synthase Catalyzes the anti-1%2C4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate%2C which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system%3B Belongs to the chorismate synthase family%3B KEGG: gsu:GSU2027 chorismate synthase gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02310 BSBS38_02311 BSBS38_02311 cheR cheR 2163841 2164611 - Protein-glutamate O-methyltransferase Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents. Contains 1 cheR-type methyltransferase domain%3B KEGG: bsu:BSU22720 chemotaxis protein methyltransferase CheR gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02311 BSBS38_02312 BSBS38_02312 BSBS38_02312 2164848 2165294 - Nucleoside-diphosphate kinase Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism%2C using a phosphorylated active-site intermediate%3B Belongs to the NDK family%3B KEGG: eco:b2518 nucleoside-diphosphate kinase gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02312 BSBS38_02313 BSBS38_02313 BSBS38_02313 2165413 2166459 - Heptaprenyl diphosphate synthase Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B Belongs to the FPP/GGPP synthase family%3B KEGG: bsu:BSU22740 heptaprenyl diphosphate synthase gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02313 BSBS38_02314 BSBS38_02314 ubiE ubiE 2166401 2167102 - Demethylmenaquinone methyltransferase Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: bsu:BSU22750 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02314 BSBS38_02315 BSBS38_02315 BSBS38_02315 2167109 2167873 - Heptaprenyl diphosphate synthase Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B KEGG: bsl:A7A1_2965 heptaprenyl diphosphate synthase gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02315 BSBS38_02316 BSBS38_02316 BSBS38_02316 2168028 2168255 - Transcription attenuation protein MtrB Required for transcription attenuation control in the trp operon. This trans-acting factor binds to trinucleotide repeats (GAG or UAG) located in the trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan%3B Belongs to the MtrB family gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02316 BSBS38_02317 BSBS38_02317 gch1 gch1 2168277 2168849 - GTP cyclohydrolase I Belongs to the GTP cyclohydrolase I family%3B KEGG: bsu:BSU22780 GTP cyclohydrolase I gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02317 BSBS38_02318 BSBS38_02318 BSBS38_02318 2169036 2169314 - DNA-binding protein HU-1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions%3B Belongs to the bacterial histone-like protein family gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02318 BSBS38_02319 BSBS38_02319 BSBS38_02319 2169688 2171166 - Stage IV sporulation protein ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Directs the assembly of the coat and exosporium to an area around the forespore gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02319 BSBS38_02320 BSBS38_02320 BSBS38_02320 2171346 2172080 - uncharacterized protein gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02320 BSBS38_02321 BSBS38_02321 BSBS38_02321 2172102 2172305 - uncharacterized protein gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02321 BSBS38_02322 BSBS38_02322 gpsA gpsA 2172643 2173680 - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: mmn:midi_00920 glycerol-3-phosphate dehydrogenase (NAD(P)+) gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02322 BSBS38_02323 BSBS38_02323 BSBS38_02323 2173698 2175008 - GTPase Der GTPase that plays an essential role in the late steps of ribosome biogenesis%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngA (Der) GTPase family%3B Contains 2 EngA-type G (guanine nucleotide-binding) domains%3B Contains 1 KH-like domain gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02323 BSBS38_02324 BSBS38_02324 BSBS38_02324 2175162 2175356 - uncharacterized protein overlaps another CDS with the same product name gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02324 BSBS38_02325 BSBS38_02325 BSBS38_02325 2175353 2176246 - uncharacterized protein overlaps another CDS with the same product name gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02325 BSBS38_02326 BSBS38_02326 BSBS38_02326 2176243 2176842 - uncharacterized protein overlaps another CDS with the same product name gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02326 BSBS38_02327 BSBS38_02327 BSBS38_02327 2176919 2177050 + uncharacterized protein gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02327 BSBS38_02328 BSBS38_02328 BSBS38_02328 2177093 2178142 - Isopentenyl-diphosphate Delta-isomerase Involved in the biosynthesis of isoprenoids. Catalyzes the 1%2C3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer%2C dimethylallyl diphosphate (DMAPP)%3B Belongs to the IPP isomerase type 2 family%3B KEGG: bsu:BSU22870 isopentenyl-diphosphate delta-isomerase gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02328 BSBS38_02329 BSBS38_02329 BSBS38_02329 2178155 2179303 - 30S ribosomal protein S1 like protein Plays a role in sporulation%3B Belongs to the ribosomal protein S1P family%3B Contains 4 S1 motif domains gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02329 BSBS38_02330 BSBS38_02330 BSBS38_02330 2179536 2180210 - UMP/CMP kinase Belongs to the cytidylate kinase family. Type 1 subfamily%3B KEGG: gxy:GLX_11090 cytidylate kinase gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02330 BSBS38_02331 BSBS38_02331 BSBS38_02331 2180289 2180465 - uncharacterized protein gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02331 BSBS38_02332 BSBS38_02332 BSBS38_02332 2180510 2181163 - uncharacterized protein Contains 1 PilZ domain gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02332 BSBS38_02333 BSBS38_02333 BSBS38_02333 2181257 2182609 - Sporulation protein YpeB Required for spore cortex hydrolysis during germination. Appears to be required for either expression%2C localization%2C activation or function of SleB. Belongs to the YpeB family gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02333 BSBS38_02334 BSBS38_02334 BSBS38_02334 2182644 2183561 - N-acetylmuramoyl-L-alanine amidase Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. Belongs to the SleB family%3B KEGG: bsu:BSU22930 N-acetylmuramoyl-L-alanine amidase gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02334 BSBS38_02335 BSBS38_02335 BSBS38_02335 2183714 2184370 - Protease PrsW Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results%2C after two other proteolytic steps catalyzed by the RasP and ClpXP proteases%2C in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor. Seems to be responsible for sensing antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress. Therefore it is a protease governing regulated intramembrane proteolysis and resistance to antimicrobial peptides in B. subtilis%3B Belongs to the protease PrsW family gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02335 BSBS38_02336 BSBS38_02336 BSBS38_02336 2184402 2185463 - Thioredoxin-disulfide reductase KEGG: bsr:I33_2359 thioredoxin reductase (NADPH) gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02336 BSBS38_02337 BSBS38_02337 gudB gudB 2185571 2186845 - Glutamate dehydrogenase GudB seems to be intrinsically inactive%2C however spontaneous mutations removing a 9-bp direct repeat within the wild-type gudB sequence activated the GudB protein and allowed more-efficient utilization of amino acids of the glutamate family. This insertion presumably causes severe destabilization of the fold of the protein%2C leading to an inactive enzyme that is very quickly degraded. The cryptic GudB serves as a buffer that may compensate for mutations in the rocG gene and that can also be decryptified for the utilization of glutamate as a single carbon source in the absence of arginine. It is unable to synthesize glutamate%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bsu:BSU22960 glutamate dehydrogenase gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02337 BSBS38_02338 BSBS38_02338 BSBS38_02338 2187001 2187585 - Adapter protein MecA Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02338 BSBS38_02339 BSBS38_02339 BSBS38_02339 2187744 2188523 - uncharacterized protein gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02339 BSBS38_02340 BSBS38_02340 BSBS38_02340 2188609 2189052 - uncharacterized protein gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02340 BSBS38_02341 BSBS38_02341 BSBS38_02341 2189396 2189836 - uncharacterized protein overlaps another CDS with the same product name gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02341 BSBS38_02342 BSBS38_02342 BSBS38_02342 2189787 2190389 - uncharacterized protein overlaps another CDS with the same product name gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02342 BSBS38_02343 BSBS38_02343 BSBS38_02343 2190416 2191906 - DNA helicase Probable DNA helicase. Required in synaptic and/or post- synaptic stages of recombination. Probably has overlapping function with RecQ (AC O34748). It probably acts to help generate ss-DNA from ds-DNA breaks%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU23020 ATP-dependent DNA helicase RecQ gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02343 BSBS38_02344 BSBS38_02344 BSBS38_02344 2191899 2192957 - DNA helicase KEGG: dsl:Dacsa_3401 ATP-dependent DNA helicase RecQ%3B overlaps another CDS with the same product name gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02344 BSBS38_02345 BSBS38_02345 BSBS38_02345 2193223 2193471 + Ferredoxin Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. This ferredoxin may act as a phosphodonor to cytochrome P450 BioI%3B Contains 1 4Fe-4S ferredoxin-type domain gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02345 BSBS38_02346 BSBS38_02346 BSBS38_02346 2193511 2194083 - Riboflavin transporter FmnP Mediates uptake of riboflavin and roseoflavin%2C a toxic riboflavin analo%3B may also transport FMN. Probably a riboflavin- binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the prokaryotic riboflavin transporter (P- RFT) (TC 2. A. 87) family gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02346 BSBS38_02347 BSBS38_02347 serA serA 2194580 2196157 + Phosphoglycerate dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU23070 D-3-phosphoglycerate dehydrogenase gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02347 BSBS38_02348 BSBS38_02348 aroD aroD 2196199 2196966 - 3-dehydroquinate dehydratase Involved in the third step of the chorismate pathway%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate%3B Belongs to the type-I 3-dehydroquinase family%3B KEGG: bsu:BSU23080 3-dehydroquinate dehydratase I gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02348 BSBS38_02349 BSBS38_02349 BSBS38_02349 2197078 2197749 - Sigma-X negative effector gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02349 BSBS38_02350 BSBS38_02350 BSBS38_02350 2197926 2198174 - Sigma-X negative effector gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02350 BSBS38_02351 BSBS38_02351 BSBS38_02351 2198113 2198697 - RNA polymerase sigma factor SigX Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism. Belongs to the sigma-70 factor family. ECF subfamily gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02351 BSBS38_02352 BSBS38_02352 resE resE 2198901 2200670 - Histidine kinase Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU23110 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02352 BSBS38_02353 BSBS38_02353 BSBS38_02353 2200667 2201389 - Transcriptional regulatory protein ResD Member of the two-component regulatory system ResD/ResE. Required for the expression of resA%2C ctaA%2C qcrABC and fn%3B activation role in global regulation of aerobic and anaerobic respiration%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02353 BSBS38_02354 BSBS38_02354 BSBS38_02354 2201470 2202645 - Cytochrome c bioproteinis protein ResC Required for the biogenesis of c-type cytochromes%3B Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02354 BSBS38_02355 BSBS38_02355 BSBS38_02355 2202665 2204293 - Cytochrome c bioproteinis protein ResB Required for the biogenesis of c-type cytochromes gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02355 BSBS38_02356 BSBS38_02356 BSBS38_02356 2204290 2204829 - Thiol-disulfide oxidoreductase ResA Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached. Does not play a role in sporulation%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02356 BSBS38_02357 BSBS38_02357 rluB rluB 2204924 2205658 - 23S rRNA pseudouridine(2605) synthase Responsible for synthesis of pseudouridine from uracil- 2633 in 23S ribosomal RNA. Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: sdl:Sdel_0065 23S rRNA pseudouridine2605 synthase gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02357 BSBS38_02358 BSBS38_02358 BSBS38_02358 2205750 2206286 - Spore maturation protein Involved in spore core dehydratio%3B might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure. Belongs to the SpmB family gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02358 BSBS38_02359 BSBS38_02359 BSBS38_02359 2206291 2206881 - Spore maturation protein gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02359 BSBS38_02360 BSBS38_02360 BSBS38_02360 2206869 2208017 - Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex). Belongs to the peptidase S11 family%3B KEGG: bsu:BSU23190 D-alanyl-D-alanine carboxypeptidase gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02360 BSBS38_02361 BSBS38_02361 BSBS38_02361 2208140 2208679 - uncharacterized protein gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02361 BSBS38_02362 BSBS38_02362 BSBS38_02362 2208734 2209327 - Segregation and condensation protein Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpB family%3B overlaps another CDS with the same product name gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02362 BSBS38_02363 BSBS38_02363 BSBS38_02363 2209317 2210102 - Segregation and condensation protein Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpA family%3B overlaps another CDS with the same product name gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02363 BSBS38_02364 BSBS38_02364 BSBS38_02364 2210352 2210876 + uncharacterized protein gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02364 BSBS38_02365 BSBS38_02365 BSBS38_02365 2210890 2211264 - Protein RibT Involved in riboflavin biosynthesis. Contains 1 N-acetyltransferase domain gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02365 BSBS38_02366 BSBS38_02366 ribH ribH 2211377 2211841 - 6%2C7-dimethyl-8-ribityllumazine synthase Catalyzes the formation of 6%2C7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3%2C4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin%3B Belongs to the DMRL synthase family%3B KEGG: slo:Shew_1190 6%2C7-dimethyl-8-ribityllumazine synthase gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02366 BSBS38_02367 BSBS38_02367 BSBS38_02367 2211874 2213070 - 3%2C4-dihydroxy-2-butanone-4-phosphate synthase Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3%2C4-dihydroxy-2-butanone 4-phosphate%3B Catalyzes the conversion of GTP to 2%2C5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP)%2C formate and pyrophosphate%3B In the N-terminal sectio%3B belongs to the DHBP synthase family%3B In the C-terminal sectio%3B belongs to the GTP cyclohydrolase II family%3B KEGG: bsu:BSU23260 3%2C4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02367 BSBS38_02368 BSBS38_02368 ribE ribE 2213085 2213732 - Riboflavin synthase Catalyzes the dismutation of two molecules of 6%2C7- dimethyl-8-ribityllumazine%2C resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil%3B Contains 2 lumazine-binding repeats%3B KEGG: hdu:HD1162 riboflavin synthase gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02368 BSBS38_02369 BSBS38_02369 ribD ribD 2213743 2214828 - Diaminohydroxyphosphoribosylaminopyrimidine deaminase Converts 2%2C5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2%2C4(1h%2C3h)- pyrimidinedione 5'-phosphate. In the N-terminal sectio%3B belongs to the cytidine and deoxycytidylate deaminase family%3B In the C-terminal sectio%3B belongs to the HTP reductase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: mxa:MXAN_4764 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02369 BSBS38_02370 BSBS38_02370 BSBS38_02370 2215221 2215565 - uncharacterized protein gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02370 BSBS38_02371 BSBS38_02371 BSBS38_02371 2215800 2216342 - Signal peptidase I Not essential for cell viability%2C but required for efficient secretion of many proteins%3B Belongs to the peptidase S26 family%3B KEGG: bsu:BSU23310 signal peptidase I gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02371 BSBS38_02372 BSBS38_02372 BSBS38_02372 2216488 2216781 - hypothetical protein gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02372 BSBS38_02373 BSBS38_02373 BSBS38_02373 2216785 2216991 - uncharacterized protein gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02373 BSBS38_02374 BSBS38_02374 BSBS38_02374 2217155 2217367 + Spore germination protein-like protein YpzD Belongs to the GerPA/GerPF family gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02374 BSBS38_02375 BSBS38_02375 ppiB ppiB 2217511 2218248 - Peptidylprolyl isomerase PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family%3B Contains 1 PPIase cyclophilin-type domain%3B KEGG: hms:HMU05620 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02375 BSBS38_02376 BSBS38_02376 BSBS38_02376 2218963 2219310 + SPBc2 prophage-derived uncharacterized protein YomG Contains 1 fibronectin type-III domain gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02376 BSBS38_02377 BSBS38_02377 BSBS38_02377 2219426 2220145 + hypothetical protein gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02377 BSBS38_02378 BSBS38_02378 BSBS38_02378 2220530 2221462 - hypothetical protein gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02378 BSBS38_02379 BSBS38_02379 BSBS38_02379 2221569 2221889 - hypothetical protein gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02379 BSBS38_02380 BSBS38_02380 BSBS38_02380 2221913 2222767 - putative peptidase C1-like protein Belongs to the peptidase C1 family gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02380 BSBS38_02381 BSBS38_02381 BSBS38_02381 2223051 2223773 + hypothetical protein gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02381 BSBS38_02382 BSBS38_02382 BSBS38_02382 2223886 2225031 - hypothetical protein gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02382 BSBS38_02383 BSBS38_02383 BSBS38_02383 2225088 2225315 - hypothetical protein gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02383 BSBS38_02384 BSBS38_02384 BSBS38_02384 2225401 2225502 - hypothetical protein gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02384 BSBS38_02385 BSBS38_02385 BSBS38_02385 2225523 2225675 - hypothetical protein gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02385 BSBS38_02386 BSBS38_02386 BSBS38_02386 2225672 2226787 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bso:BSNT_02017 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02386 BSBS38_02387 BSBS38_02387 BSBS38_02387 2227182 2227646 + Antitoxin YobK Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the RNase activity of cognate toxin YobL%2C as well as its ability to inhibit growth upon expression in E. coli. Does not have antitoxin activity on other toxins with the LXG toxin domain gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02387 BSBS38_02388 BSBS38_02388 BSBS38_02388 2227706 2228944 - Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02388 BSBS38_02389 BSBS38_02389 BSBS38_02389 2229069 2229434 - hypothetical protein gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02389 BSBS38_02390 BSBS38_02390 BSBS38_02390 2229478 2230899 + hypothetical protein gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02390 BSBS38_02391 BSBS38_02391 BSBS38_02391 2230930 2231073 + hypothetical protein gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02391 BSBS38_02392 BSBS38_02392 BSBS38_02392 2231326 2231565 - hypothetical protein gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02392 BSBS38_02393 BSBS38_02393 BSBS38_02393 2231688 2231915 - hypothetical protein gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02393 BSBS38_02394 BSBS38_02394 BSBS38_02394 2232077 2232388 + hypothetical protein gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02394 BSBS38_02395 BSBS38_02395 BSBS38_02395 2232403 2232795 + hypothetical protein gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02395 BSBS38_02396 BSBS38_02396 BSBS38_02396 2232989 2233237 + hypothetical protein gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02396 BSBS38_02397 BSBS38_02397 BSBS38_02397 2233943 2234197 - hypothetical protein gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02397 BSBS38_02398 BSBS38_02398 BSBS38_02398 2234325 2234756 - Peptidylprolyl isomerase PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family%3B Contains 1 PPIase cyclophilin-type domain%3B KEGG: bsu:BSU23360 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02398 BSBS38_02399 BSBS38_02399 BSBS38_02399 2234848 2235042 - Peptidylprolyl isomerase PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family%3B Contains 1 PPIase cyclophilin-type domain%3B KEGG: bsu:BSU23360 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02399 BSBS38_02400 BSBS38_02400 BSBS38_02400 2235299 2236171 + uncharacterized protein gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02400 BSBS38_02401 BSBS38_02401 lysA lysA 2236201 2237526 - Diaminopimelate decarboxylase Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine%3B Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily%3B KEGG: bsl:A7A1_3031 diaminopimelate decarboxylase gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02401 BSBS38_02402 BSBS38_02402 BSBS38_02402 2237626 2239107 - Stage V sporulation protein AF Belongs to the GerABKA family gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02402 BSBS38_02403 BSBS38_02403 BSBS38_02403 2239058 2239669 - Stage V sporulation protein AE gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02403 BSBS38_02404 BSBS38_02404 BSBS38_02404 2239677 2240027 - Stage V sporulation protein AEB gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02404 BSBS38_02405 BSBS38_02405 BSBS38_02405 2240029 2241045 - Stage V sporulation protein AD gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02405 BSBS38_02406 BSBS38_02406 BSBS38_02406 2241058 2241510 - Stage V sporulation protein AC gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02406 BSBS38_02407 BSBS38_02407 BSBS38_02407 2241523 2241948 - Stage V sporulation protein gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02407 BSBS38_02408 BSBS38_02408 BSBS38_02408 2241938 2242558 - Stage V sporulation protein AA gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02408 BSBS38_02409 BSBS38_02409 BSBS38_02409 2242685 2243452 - RNA polymerase sigma-F factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02409 BSBS38_02410 BSBS38_02410 BSBS38_02410 2243464 2243904 - Non-specific serine/threonine protein kinase Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition%3B Belongs to the anti-sigma-factor family%3B KEGG: bsu:BSU23460 stage II sporulation protein AB (anti-sigma F factor) gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02410 BSBS38_02411 BSBS38_02411 BSBS38_02411 2243901 2244254 - Anti-sigma F factor antagonist In the phosphorylated form it could act as an anti-anti- sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02411 BSBS38_02412 BSBS38_02412 BSBS38_02412 2244350 2245519 - Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bsu:BSU23480 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02412 BSBS38_02413 BSBS38_02413 punA punA 2245673 2246488 - Purine-nucleoside phosphorylase The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules%2C with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine%2C inosine%2C 2'-deoxyguanosine and 2'-deoxyinosine%3B Belongs to the PNP/MTAP phosphorylase family%3B KEGG: mes:Meso_0150 purine-nucleoside phosphorylase gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02413 BSBS38_02414 BSBS38_02414 deoB deoB 2246501 2247685 - Phosphopentomutase Phosphotransfer between the C1 and C5 carbon atoms of pentose. Belongs to the phosphopentomutase family%3B KEGG: bsu:BSU23500 phosphopentomutase gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02414 BSBS38_02415 BSBS38_02415 BSBS38_02415 2247846 2248736 - Tyrosine recombinase XerC Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02415 BSBS38_02416 BSBS38_02416 BSBS38_02416 2248744 2248971 - putative membrane protein YqzK gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02416 BSBS38_02417 BSBS38_02417 BSBS38_02417 2249096 2249545 - Ferric uptake regulation protein Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes. Belongs to the Fur family gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02417 BSBS38_02418 BSBS38_02418 BSBS38_02418 2249658 2250302 - Stage II sporulation protein Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02418 BSBS38_02419 BSBS38_02419 BSBS38_02419 2250403 2250618 - uncharacterized protein gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02419 BSBS38_02420 BSBS38_02420 sfcA sfcA 2250715 2252034 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU23550 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02420 BSBS38_02421 BSBS38_02421 BSBS38_02421 2252052 2253458 - Malate-2H(+)/Na(+)-lactate antiporter Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport%2C in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02421 BSBS38_02422 BSBS38_02422 aspA aspA 2253599 2255026 - Aspartate ammonia-lyase Belongs to the class-II fumarase/aspartase family. Aspartase subfamily%3B KEGG: bsu:BSU23570 aspartate ammonia-lyase gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02422 BSBS38_02423 BSBS38_02423 BSBS38_02423 2255071 2256060 - Asparaginase Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: bsu:BSU23580 L-asparaginase gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02423 BSBS38_02424 BSBS38_02424 BSBS38_02424 2256242 2256592 + HTH-type transcriptional regulator AnsR Transcriptional repressor for the ans operon coding for L-asparaginase and L-aspartase. NH4(+) may influence this repression. Contains 1 HTH cro/C1-type DNA-binding domain gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02424 BSBS38_02425 BSBS38_02425 BSBS38_02425 2256601 2257764 - uncharacterized protein To M. jannaschii MJ0043 N-terminal region gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02425 BSBS38_02426 BSBS38_02426 BSBS38_02426 2257761 2258318 - ADP-ribose diphosphatase Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity)%3B Belongs to the Nudix hydrolase family. NudF subfamily%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU23610 ADP-ribose pyrophosphatase gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02426 BSBS38_02427 BSBS38_02427 BSBS38_02427 2258393 2258515 + hypothetical protein gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02427 BSBS38_02428 BSBS38_02428 BSBS38_02428 2258578 2259498 + Pyridoxine 4-dehydrogenase Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: rru:Rru_A1059 pyridoxine 4-dehydrogenase gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02428 BSBS38_02429 BSBS38_02429 BSBS38_02429 2259530 2259754 - uncharacterized protein gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02429 BSBS38_02430 BSBS38_02430 BSBS38_02430 2259914 2260831 + uncharacterized protein gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02430 BSBS38_02431 BSBS38_02431 BSBS38_02431 2260871 2261110 - uncharacterized protein gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02431 BSBS38_02432 BSBS38_02432 BSBS38_02432 2261123 2261446 - uncharacterized protein gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02432 BSBS38_02433 BSBS38_02433 BSBS38_02433 2261443 2262474 - UPF0157 protein YqkA In the C-terminal sectio%3B belongs to the UPF0157 (GrpB) family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3057 null%3B Transferring groups other than amino-acyl groups gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02433 BSBS38_02434 BSBS38_02434 BSBS38_02434 2262467 2262808 - Glutathione transferase Contains 1 ABM domain%3B KEGG: thi:THI_2919 glutathione S-transferase gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02434 BSBS38_02435 BSBS38_02435 BSBS38_02435 2262821 2263291 - uncharacterized protein Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK2777 null%3B Transferring groups other than amino-acyl groups gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02435 BSBS38_02436 BSBS38_02436 BSBS38_02436 2263477 2263815 - uncharacterized protein gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02436 BSBS38_02437 BSBS38_02437 dpo4 dpo4 2263812 2265050 - DNA-directed DNA polymerase Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII (By similarity)%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: bsu:BSU23710 DNA polymerase IV gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02437 BSBS38_02438 BSBS38_02438 BSBS38_02438 2265216 2265422 + uncharacterized protein gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02438 BSBS38_02439 BSBS38_02439 BSBS38_02439 2265925 2267157 + putative MFS-type transporter YqjV Belongs to the major facilitator superfamily. TCR/Tet family gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02439 BSBS38_02440 BSBS38_02440 BSBS38_02440 2267208 2267366 + uncharacterized protein gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02440 BSBS38_02441 BSBS38_02441 gpmB gpmB 2267363 2267749 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) KEGG: mlu:Mlut_09490 probable phosphoglycerate mutase gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02441 BSBS38_02442 BSBS38_02442 coaA coaA 2267754 2268713 - Pantothenate kinase Belongs to the prokaryotic pantothenate kinase family%3B KEGG: bsu:BSU23760 type I pantothenate kinase gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02442 BSBS38_02443 BSBS38_02443 dsdA dsdA 2268785 2270131 - D-serine ammonia-lyase Belongs to the serine/threonine dehydratase family. DsdA subfamily%3B KEGG: bsu:BSU23770 D-serine dehydratase gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02443 BSBS38_02444 BSBS38_02444 BSBS38_02444 2270207 2270986 - putative oxidoreductase YqjQ Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02444 BSBS38_02445 BSBS38_02445 BSBS38_02445 2270992 2271951 - putative metallo-hydrolase YqjP Belongs to the metallo-beta-lactamase superfamily gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02445 BSBS38_02446 BSBS38_02446 BSBS38_02446 2272355 2273191 + Pyrroline-5-carboxylate reductase Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU23800 pyrroline-5-carboxylate reductase gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02446 BSBS38_02447 BSBS38_02447 BSBS38_02447 2273232 2274875 - uncharacterized protein To B. subtilis RocB gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02447 BSBS38_02448 BSBS38_02448 BSBS38_02448 2275047 2276063 + NADPH dehydrogenase Catalyzes the reduction of the double bond of an array of alpha%2Cbeta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily%3B KEGG: bsu:BSU23820 NADPH2 dehydrogenase gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02448 BSBS38_02449 BSBS38_02449 BSBS38_02449 2276173 2276934 + 3-oxoadipate enol-lactonase KEGG: ppi:YSA_10980 3-oxoadipate enol-lactonase gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02449 BSBS38_02450 BSBS38_02450 BSBS38_02450 2276978 2277127 - 50S ribosomal protein L33 Belongs to the ribosomal protein L33P family gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02450 BSBS38_02451 BSBS38_02451 BSBS38_02451 2277209 2278132 - Ribonuclease Z Zinc phosphodiesterase%2C which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation%2C by removing a 3'-trailer from precursor tRNA%3B Belongs to the RNase Z family%3B KEGG: ebi:EbC_43140 ribonuclease Z gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02451 BSBS38_02452 BSBS38_02452 g6pD g6pD 2278359 2279828 + Glucose-6-phosphate dehydrogenase (NADP(+)) Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone%3B Belongs to the glucose-6-phosphate dehydrogenase family%3B KEGG: bsu:BSU23850 glucose-6-phosphate 1-dehydrogenase gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02452 BSBS38_02453 BSBS38_02453 gntZ gntZ 2279940 2281349 - Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NADP to NADPH%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: eco:b2029 6-phosphogluconate dehydrogenase gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02453 BSBS38_02454 BSBS38_02454 BSBS38_02454 2281459 2282703 - DNA-directed DNA polymerase Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: bsr:I33_2464 DNA polymerase IV gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02454 BSBS38_02455 BSBS38_02455 BSBS38_02455 2282767 2283063 + Membrane protein insertion and folding monitor Sensor protein that upregulates translation of the secondary membrane protein insertase (MisCB/YqjG) when activity of the primary membrane protein insertase (MisCA/SpoIIIJ) is limited. Acts as a ribosome-nascent chain complex. When the primary membrane protein insertase activity or level is reduced%2C the membrane insertion of MifM is impaired%2C which induces arrest of MifM translation and unfolding of the mRNA hairpin. Unfolding leads to translation of the downstream gene%2C which encodes the secondary membrane protein insertase MisCB/YqjG. Translation arrest of MifM is mediated by interaction of its C-terminal domain with the ribosomal polypeptide exit tunnel. Undergoes multisite stalling%2C which may allow a sufficient duration of ribosomal stalling and consequently sufficient levels of MisCB/YqjG gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02455 BSBS38_02456 BSBS38_02456 BSBS38_02456 2283094 2283921 + Membrane protein insertase MisCB Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. It has an overlapping%2C although partly distinct%2C function compared to SpoIIIJ(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02456 BSBS38_02457 BSBS38_02457 BSBS38_02457 2284000 2284830 + uncharacterized protein gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02457 BSBS38_02458 BSBS38_02458 BSBS38_02458 2284871 2285986 - Propionyl-CoA carboxylase Could be a peptidase. Belongs to the peptidase M20A family%3B KEGG: bya:BANAU_2374 propionyl-CoA carboxylase beta chain gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02458 BSBS38_02459 BSBS38_02459 BSBS38_02459 2286004 2287533 - Propionyl-CoA carboxylase Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: bsr:I33_2469 propionyl-CoA carboxylase beta chain gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02459 BSBS38_02460 BSBS38_02460 mceE mceE 2287520 2287942 - Methylmalonyl-CoA epimerase Belongs to the glyoxalase I family%3B KEGG: gsu:GSU3303 methylmalonyl-CoA/ethylmalonyl-CoA epimerase gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02460 BSBS38_02461 BSBS38_02461 BSBS38_02461 2288032 2288124 + hypothetical protein gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02461 BSBS38_02462 BSBS38_02462 BSBS38_02462 2288144 2288674 - Putative L%2CD-transpeptidase YqjB Belongs to the YkuD family gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02462 BSBS38_02463 BSBS38_02463 BSBS38_02463 2288726 2289694 - uncharacterized protein gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02463 BSBS38_02464 BSBS38_02464 phnC phnC 2289765 2290487 - Phosphonate-transporting ATPase Part of a binding-protein-dependent transport system for arginine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: ecoo:ECRM13514_5321 phosphonate transport system ATP-binding protein gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02464 BSBS38_02465 BSBS38_02465 BSBS38_02465 2290480 2291139 - Arginine transport system permease protein ArtQ Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02465 BSBS38_02466 BSBS38_02466 BSBS38_02466 2291219 2291986 - Arginine-binding extracellular protein ArtP Part of a binding-protein-dependent transport system for arginine%3B Belongs to the bacterial solute-binding protein 3 family gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02466 BSBS38_02467 BSBS38_02467 BSBS38_02467 2292254 2292691 - UPF0403 protein Belongs to the UPF0403 family gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02467 BSBS38_02468 BSBS38_02468 BSBS38_02468 2292852 2293745 + Diacylglycerol kinase (ATP) May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: ssd:SPSINT_1652 diacylglycerol kinase (ATP) gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02468 BSBS38_02469 BSBS38_02469 BSBS38_02469 2293846 2294913 + Multidrug resistance protein Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances%2C including such structurally diverse compounds as ethidium bromide%2C rhodamine and acridine dyes%2C tetraphenylphosphonium%2C puromycin%2C chloramphenicol%2C doxorubicin%2C and fluoroquinolone antibiotics. Belongs to the major facilitator superfamily. TCR/Tet family gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02469 BSBS38_02470 BSBS38_02470 BSBS38_02470 2295081 2295917 + Multidrug-efflux transporter 1 regulator Activates transcription of the bmr gene in response to structurally dissimilar drugs. Binds rhodamine as an inducer. Contains 1 HTH merR-type DNA-binding domain gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02470 BSBS38_02471 BSBS38_02471 bkdB bkdB 2295972 2297246 - Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: bsu:BSU24030 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02471 BSBS38_02472 BSBS38_02472 BSBS38_02472 2297269 2298252 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) KEGG: sur:STAUR_4870 2-oxoisovalerate dehydrogenase E1 component beta subunit gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02472 BSBS38_02473 BSBS38_02473 BSBS38_02473 2298266 2299258 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the BCKDHA family%3B KEGG: bsu:BSU24050 2-oxoisovalerate dehydrogenase E1 component alpha subunit gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02473 BSBS38_02474 BSBS38_02474 BSBS38_02474 2299280 2300704 - Glutathione-disulfide reductase The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: abo:ABO_1423 glutathione reductase (NADPH) gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02474 BSBS38_02475 BSBS38_02475 BSBS38_02475 2300725 2301810 - Butyrate kinase Belongs to the acetokinase family%3B KEGG: bsu:BSU24070 butyrate kinase gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02475 BSBS38_02476 BSBS38_02476 BSBS38_02476 2301835 2302929 - Leucine dehydrogenase Catalyzes the reversible deamination of L-leucine to 4- methyl-2-oxopentanoate. Can also use other substrates such as L- isoleucine%2C L-valine and L-2-aminobutyrate. The 2-oxo analogs of branched-chain and straight-chain amino acids serve as good substrates for the reverse reaction%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bsu:BSU24080 leucine dehydrogenase gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02476 BSBS38_02477 BSBS38_02477 BSBS38_02477 2302941 2303840 - Phosphate butyryltransferase Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate. Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bsu:BSU24090 phosphate butyryltransferase gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02477 BSBS38_02478 BSBS38_02478 BSBS38_02478 2303965 2306043 - Histidine kinase Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 2 PAS (PER-ARNT-SIM) domains%3B Contains 1 sigma-54 factor interaction domain%3B KEGG: amt:Amet_2967 two-component system%2C CitB family%2C sensor histidine kinase DctS gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02478 BSBS38_02479 BSBS38_02479 BSBS38_02479 2306196 2306432 + uncharacterized protein gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02479 BSBS38_02480 BSBS38_02480 BSBS38_02480 2306474 2307379 - Carboxyvinyl-carboxyphosphonate phosphorylmutase Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R%2C3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family%3B KEGG: apt:APA01_03610 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02480 BSBS38_02481 BSBS38_02481 prpD prpD 2307396 2308814 - 2-methylcitrate dehydratase Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the stereospecific dehydration of (2S%2C3S)-2- methylcitrate (2-MC) to yield the cis isomer of 2-methyl- aconitate. Could also catalyze the dehydration of citrate and the hydration of cis-aconitate%3B Belongs to the PrpD family%3B KEGG: bsu:BSU24130 2-methylcitrate dehydratase gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02481 BSBS38_02482 BSBS38_02482 BSBS38_02482 2308829 2309947 - Citrate (Si)-synthase Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Could catalyze the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield (2S%2C3S)-2-methylcitrate (2-MC) and CoA (By similarity). Catalyzes the condensation of oxaloacetate with acetyl-CoA (PubMed:8759838)%3B Belongs to the citrate synthase family%3B KEGG: bsu:BSU24140 citrate synthase gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02482 BSBS38_02483 BSBS38_02483 caiA caiA 2309981 2310457 - Isobutyryl-CoA dehydrogenase%2C mitochondrial Has very high activity toward isobutyryl-CoA. Is an isobutyryl-CoA dehydrogenase that functions in valine catabolism (By similarity)%3B Belongs to the acyl-CoA dehydrogenase family%3B KEGG: eco:b0039 crotonobetainyl-CoA dehydrogenase%3B With other acceptors gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02483 BSBS38_02484 BSBS38_02484 BSBS38_02484 2310655 2311113 - Acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: ppu:PP_3492 null%3B With other acceptors gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02484 BSBS38_02485 BSBS38_02485 paaH paaH 2311141 2312004 - 3-hydroxybutyryl-CoA dehydrogenase Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: bsu:BSU24160 3-hydroxybutyryl-CoA dehydrogenase gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02485 BSBS38_02486 BSBS38_02486 BSBS38_02486 2312029 2313210 - Acetyl-CoA C-acetyltransferase Belongs to the thiolase family%3B KEGG: bsu:BSU24170 acetyl-CoA C-acetyltransferase gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02486 BSBS38_02487 BSBS38_02487 BSBS38_02487 2313345 2314076 - Glycerophosphodiester phosphodiesterase Contains 1 GP-PDE domain%3B KEGG: pgb:H744_1c0275 glycerophosphoryl diester phosphodiesterase gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02487 BSBS38_02488 BSBS38_02488 BSBS38_02488 2314155 2314769 - N-acetylmuramoyl-L-alanine amidase Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bsu:BSU24190 N-acetylmuramoyl-L-alanine amidase gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02488 BSBS38_02489 BSBS38_02489 BSBS38_02489 2314795 2315091 - putative lipoprotein YqiH gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02489 BSBS38_02490 BSBS38_02490 nemA nemA 2315594 2316742 + putative NADH-dependent flavin oxidoreductase YqiG Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: vph:VPUCM_20674 N-ethylmaleimide reductase%3B Oxidoreductases gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02490 BSBS38_02491 BSBS38_02491 BSBS38_02491 2316785 2316898 - hypothetical protein gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02491 BSBS38_02492 BSBS38_02492 BSBS38_02492 2317207 2318010 - Stage 0 sporulation protein May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB%2C activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) (By similarity)%3B Contains 1 response regulatory domain gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02492 BSBS38_02493 BSBS38_02493 BSBS38_02493 2318286 2319566 - SpoIVB peptidase Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter%3B Contains 1 PDZ (DHR) domain%3B Contains 1 peptidase S55 domain%3B KEGG: bsu:BSU24230 stage IV sporulation protein B gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02493 BSBS38_02494 BSBS38_02494 BSBS38_02494 2319741 2321471 - DNA repair protein RecN Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers%2C foci that are the site of double-strand DNA break(s)%2C followed by RecO and then RecF. Belongs to the RecN family gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02494 BSBS38_02495 BSBS38_02495 BSBS38_02495 2321508 2321957 - Arginine repressor Regulates arginine biosynthesis genes%3B Belongs to the ArgR family gene gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02495 BSBS38_02496 BSBS38_02496 tlyA tlyA 2322055 2322900 - 23S rRNA (cytidine(1920)-2'-O)-methyltransferase Belongs to the TlyA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: afw:Anae109_1137 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02496 BSBS38_02497 BSBS38_02497 BSBS38_02497 2322897 2324798 - 1-deoxy-D-xylulose-5-phosphate synthase Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: bsu:BSU24270 1-deoxy-D-xylulose-5-phosphate synthase gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02497 BSBS38_02498 BSBS38_02498 ggpS ggpS 2324973 2325863 - Dimethylallyltranstransferase Belongs to the FPP/GGPP synthase family%3B KEGG: bsu:BSU24280 geranylgeranyl diphosphate synthase%2C type II gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02498 BSBS38_02499 BSBS38_02499 xseB xseB 2325853 2326107 - Exodeoxyribonuclease VII Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseB family%3B KEGG: bsu:BSU24290 exodeoxyribonuclease VII small subunit%3B overlaps another CDS with the same product name gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02499 BSBS38_02500 BSBS38_02500 xseA xseA 2326104 2327450 - Exodeoxyribonuclease VII Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseA family%3B KEGG: bsu:BSU24300 exodeoxyribonuclease VII large subunit%3B overlaps another CDS with the same product name gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02500 BSBS38_02501 BSBS38_02501 folD folD 2327588 2328439 - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Catalyzes the oxidation of 5%2C10- methylenetetrahydrofolate to 5%2C10-methenyltetrahydrofolate and then the hydrolysis of 5%2C10-methenyltetrahydrofolate to 10- formyltetrahydrofolate%3B Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family%3B KEGG: bma:BMA1724 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02501 BSBS38_02502 BSBS38_02502 BSBS38_02502 2328451 2328846 - N utilization substance protein B like protein Involved in the transcription termination process%3B Belongs to the NusB family gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02502 BSBS38_02503 BSBS38_02503 BSBS38_02503 2329109 2329516 - uncharacterized protein Belongs to the asp23 family gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02503 BSBS38_02504 BSBS38_02504 accC accC 2329537 2330889 - Acetyl-CoA carboxylase Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02504 BSBS38_02505 BSBS38_02505 BSBS38_02505 2330901 2331380 - Biotin carboxyl carrier protein of acetyl-CoA carboxylase This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. Contains 1 biotinyl-binding domain gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02505 BSBS38_02506 BSBS38_02506 BSBS38_02506 2331537 2332193 - Stage III sporulation protein AH Involved in forespore engulfment. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02506 BSBS38_02507 BSBS38_02507 BSBS38_02507 2332194 2332883 - Stage III sporulation protein AG gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02507 BSBS38_02508 BSBS38_02508 BSBS38_02508 2332876 2333496 - Stage III sporulation protein AF gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02508 BSBS38_02509 BSBS38_02509 BSBS38_02509 2333510 2334709 - Stage III sporulation protein AE Required during sporulation for activation of sigma factor SpoIIIG/SigG after engulfment is completed in the prespore. Overexpression in the absence of SpoIIIJ is synthetically lethal gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02509 BSBS38_02510 BSBS38_02510 BSBS38_02510 2334728 2335129 - Stage III sporulation protein AD gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02510 BSBS38_02511 BSBS38_02511 BSBS38_02511 2335136 2335342 - Stage III sporulation protein AC gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02511 BSBS38_02512 BSBS38_02512 BSBS38_02512 2335365 2335880 - Stage III sporulation protein gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02512 BSBS38_02513 BSBS38_02513 BSBS38_02513 2335874 2336797 - Stage III sporulation protein AA gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02513 BSBS38_02514 BSBS38_02514 BSBS38_02514 2336873 2337154 - uncharacterized protein gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02514 BSBS38_02515 BSBS38_02515 BSBS38_02515 2337299 2337856 - Elongation factor P Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA%2C thus increasing their reactivity as acceptors for peptidyl transferase%3B Belongs to the elongation factor P family gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02515 BSBS38_02516 BSBS38_02516 pepP pepP 2337881 2338942 - Xaa-Pro aminopeptidase Belongs to the peptidase M24B family%3B KEGG: bsu:BSU24460 Xaa-Pro aminopeptidase gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02516 BSBS38_02517 BSBS38_02517 aroQ aroQ 2338939 2339385 - 3-dehydroquinate dehydratase Catalyzes a trans-dehydration via an enolate intermediate%3B Belongs to the type-II 3-dehydroquinase family%3B KEGG: bsu:BSU24470 3-dehydroquinate dehydratase II gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02517 BSBS38_02518 BSBS38_02518 BSBS38_02518 2339472 2340005 - uncharacterized protein gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02518 BSBS38_02519 BSBS38_02519 BSBS38_02519 2340235 2341191 + uncharacterized protein gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02519 BSBS38_02520 BSBS38_02520 BSBS38_02520 2341231 2341626 + uncharacterized protein gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02520 BSBS38_02521 BSBS38_02521 BSBS38_02521 2341682 2342497 - uncharacterized protein Probable lipid hydrolase%3B Contains 1 patatin domain gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02521 BSBS38_02522 BSBS38_02522 BSBS38_02522 2342623 2343051 - Transcriptional regulator MntR Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon%3B Contains 1 HTH dtxR-type DNA-binding domain gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02522 BSBS38_02523 BSBS38_02523 BSBS38_02523 2343151 2343987 - Lipoate--protein ligase Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH%2C an intermediate carrier during protein lipoylation%3B Belongs to the octanoyltransferase LipM family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU24530 lipoate-protein ligase A gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02523 BSBS38_02524 BSBS38_02524 glpE glpE 2344178 2344558 + Thiosulfate sulfurtransferase Contains 1 rhodanese domain%3B KEGG: pao:Pat9b_3716 thiosulfate sulfurtransferase gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02524 BSBS38_02525 BSBS38_02525 BSBS38_02525 2344593 2346059 - Glycine dehydrogenase (aminomethyl-transferring) The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. C-terminal subunit subfamily%3B KEGG: bsu:BSU24550 glycine dehydrogenase subunit 2%3B overlaps another CDS with the same product name gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02525 BSBS38_02526 BSBS38_02526 BSBS38_02526 2346052 2347398 - Glycine dehydrogenase (aminomethyl-transferring) The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. N-terminal subunit subfamily%3B KEGG: bsu:BSU24560 glycine dehydrogenase subunit 1%3B overlaps another CDS with the same product name gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02526 BSBS38_02527 BSBS38_02527 gcvT gcvT 2347428 2348516 - Aminomethyltransferase The glycine cleavage system catalyzes the degradation of glycine%3B Belongs to the GcvT family%3B KEGG: tig:THII_2082 aminomethyltransferase gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02527 BSBS38_02528 BSBS38_02528 hepA hepA 2348958 2350631 + putative ATP-dependent helicase YqhH Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: eco:b0059 ATP-dependent helicase HepA%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02528 BSBS38_02529 BSBS38_02529 BSBS38_02529 2350652 2351446 + uncharacterized protein gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02529 BSBS38_02530 BSBS38_02530 BSBS38_02530 2351629 2351802 + Protein SinI Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. Contains 1 Sin domain gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02530 BSBS38_02531 BSBS38_02531 BSBS38_02531 2351830 2352177 + HTH-type transcriptional regulator SinR Affects autolysin level and flagellation. Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02531 BSBS38_02532 BSBS38_02532 BSBS38_02532 2352263 2353048 - Spore coat-associated protein Belongs to the peptidase M73 family gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02532 BSBS38_02533 BSBS38_02533 sipW sipW 2353112 2353684 - Signal peptidase I Belongs to the peptidase S26B family%3B KEGG: bsu:BSU24630 signal peptidase%2C endoplasmic reticulum-type%3B Acting on peptide bonds (peptidases) gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02533 BSBS38_02534 BSBS38_02534 BSBS38_02534 2353668 2354429 - uncharacterized protein gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02534 BSBS38_02535 BSBS38_02535 BSBS38_02535 2354650 2355027 + uncharacterized protein gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02535 BSBS38_02536 BSBS38_02536 BSBS38_02536 2355069 2355248 - uncharacterized protein gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02536 BSBS38_02537 BSBS38_02537 BSBS38_02537 2355319 2355693 - ComG operon protein Required for transformation and DNA binding gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02537 BSBS38_02538 BSBS38_02538 BSBS38_02538 2355694 2355972 - ComG operon protein Required for transformation and DNA binding gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02538 BSBS38_02539 BSBS38_02539 BSBS38_02539 2356103 2356450 - ComG operon protein Required for transformation and DNA binding%3B overlaps another CDS with the same product name gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02539 BSBS38_02540 BSBS38_02540 BSBS38_02540 2356434 2356865 - ComG operon protein Required for transformation and DNA binding%3B overlaps another CDS with the same product name gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02540 BSBS38_02541 BSBS38_02541 BSBS38_02541 2356855 2357151 - ComG operon protein 3 like protein Required for transformation and DNA binding%3B Belongs to the ComGC family gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02541 BSBS38_02542 BSBS38_02542 BSBS38_02542 2357165 2358202 - ComG operon protein Required for transformation and DNA binding%3B Belongs to the GSP F family%3B overlaps another CDS with the same product name gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02542 BSBS38_02543 BSBS38_02543 BSBS38_02543 2358189 2359259 - ComG operon protein Required for uptake of DNA by competent cells%3B Belongs to the GSP E family%3B overlaps another CDS with the same product name gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02543 BSBS38_02544 BSBS38_02544 BSBS38_02544 2359471 2359668 - hypothetical protein gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02544 BSBS38_02545 BSBS38_02545 BSBS38_02545 2359670 2360623 - Magnesium transport protein CorA Mediates influx of magnesium ions%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02545 BSBS38_02546 BSBS38_02546 BSBS38_02546 2360774 2362093 + UPF0053 protein YqhB Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02546 BSBS38_02547 BSBS38_02547 BSBS38_02547 2362146 2362982 - RsbT co-antagonist protein RsbRD One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02547 BSBS38_02548 BSBS38_02548 BSBS38_02548 2363069 2363139 + tRNA-Gln tRNA gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02548 BSBS38_02549 BSBS38_02549 arsC arsC 2363206 2363586 - Arsenate reductase (glutaredoxin) Regulates transcription of a subregulon within the general stress response. Exerts positive and negative effects in response to ethanol stress%3B Belongs to the ArsC family%3B KEGG: bsu:BSU24770 arsenate reductase gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02549 BSBS38_02550 BSBS38_02550 BSBS38_02550 2363818 2364063 + uncharacterized protein gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02550 BSBS38_02551 BSBS38_02551 BSBS38_02551 2364103 2364738 - Hydroxyacylglutathione hydrolase Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: spa:M6_Spy0554 hydroxyacylglutathione hydrolase gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02551 BSBS38_02552 BSBS38_02552 BSBS38_02552 2364895 2365068 + uncharacterized protein gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02552 BSBS38_02553 BSBS38_02553 BSBS38_02553 2365100 2365414 - UPF0045 protein YqgV Belongs to the UPF0045 family gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02553 BSBS38_02554 BSBS38_02554 BSBS38_02554 2365417 2366472 - putative lipoprotein YqgU gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02554 BSBS38_02555 BSBS38_02555 yqgT yqgT 2366540 2367667 - Gamma-D-glutamyl-meso-diaminopimelate peptidase Belongs to the peptidase M14 family%3B KEGG: bsu:BSU24830 g-D-glutamyl-meso-diaminopimelate peptidase gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02555 BSBS38_02556 BSBS38_02556 BSBS38_02556 2367753 2369669 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Belongs to the LTA synthase family%3B KEGG: lrh:LGG_00830 lipoteichoic acid synthase gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02556 BSBS38_02557 BSBS38_02557 BSBS38_02557 2369786 2370751 - Glucokinase Belongs to the ROK (NagC/XylR) family%3B KEGG: bsu:BSU24850 glucokinase gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02557 BSBS38_02558 BSBS38_02558 BSBS38_02558 2370762 2370977 - uncharacterized protein gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02558 BSBS38_02559 BSBS38_02559 BSBS38_02559 2371087 2372610 - Rhomboid protease Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter%3B Belongs to the peptidase S54 family%3B Contains 2 TPR repeats%3B KEGG: bsu:BSU24870 rhomboid protease GluP gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02559 BSBS38_02560 BSBS38_02560 BSBS38_02560 2372700 2372873 - uncharacterized protein gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02560 BSBS38_02561 BSBS38_02561 BSBS38_02561 2372940 2373503 - 5-formyltetrahydrofolate cyclo-ligase Belongs to the 5-formyltetrahydrofolate cyclo-ligase family%3B KEGG: bsu:BSU24890 5-formyltetrahydrofolate cyclo-ligase gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02561 BSBS38_02562 BSBS38_02562 BSBS38_02562 2373588 2373737 - 50S ribosomal protein L33 Belongs to the ribosomal protein L33P family gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02562 BSBS38_02563 BSBS38_02563 BSBS38_02563 2373821 2374900 - 1%2C4-alpha-glucan branching enzyme Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bpf:BpOF4_13925 1%2C4-alpha-glucan branching enzyme gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02563 BSBS38_02564 BSBS38_02564 BSBS38_02564 2374897 2375367 - uncharacterized protein gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02564 BSBS38_02565 BSBS38_02565 BSBS38_02565 2375547 2375900 + uncharacterized protein overlaps another CDS with the same product name gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02565 BSBS38_02566 BSBS38_02566 BSBS38_02566 2375897 2376361 + uncharacterized protein overlaps another CDS with the same product name gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02566 BSBS38_02567 BSBS38_02567 pstB pstB 2376389 2377171 - Phosphate-transporting ATPase Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU24950 phosphate transport system ATP-binding protein gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02567 BSBS38_02568 BSBS38_02568 BSBS38_02568 2377182 2377991 - Phosphate-transporting ATPase Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU24960 phosphate transport system ATP-binding protein gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02568 BSBS38_02569 BSBS38_02569 BSBS38_02569 2378012 2378896 - putative ABC transporter permease protein YqgI Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02569 BSBS38_02570 BSBS38_02570 BSBS38_02570 2378896 2379825 - putative ABC transporter permease protein YqgH Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02570 BSBS38_02571 BSBS38_02571 BSBS38_02571 2379894 2380796 - Phosphate-binding protein PstS Part of the ABC transporter complex PstSACB involved in phosphate import%3B Belongs to the PstS family gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02571 BSBS38_02572 BSBS38_02572 BSBS38_02572 2380952 2383102 - uncharacterized protein Belongs to the transpeptidase family%3B KEGG: seq:SZO_13590 penicillin-binding protein 2B%3B Aminoacyltransferases gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02572 BSBS38_02573 BSBS38_02573 BSBS38_02573 2383217 2384509 - uncharacterized protein gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02573 BSBS38_02574 BSBS38_02574 BSBS38_02574 2384616 2385224 - Superoxide dismutase Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family%3B KEGG: eic:NT01EI_2109 superoxide dismutase%2C Fe-Mn family gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02574 BSBS38_02575 BSBS38_02575 BSBS38_02575 2385403 2385885 - uncharacterized protein gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02575 BSBS38_02576 BSBS38_02576 BSBS38_02576 2385995 2386756 + uncharacterized protein gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02576 BSBS38_02577 BSBS38_02577 BSBS38_02577 2386851 2387150 + uncharacterized protein Contains 1 LysM repeat gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02577 BSBS38_02578 BSBS38_02578 gcpE gcpE 2387279 2388406 + (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) Converts 2C-methyl-D-erythritol 2%2C4-cyclodiphosphate (ME-2%2C4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate%3B Belongs to the IspG family%3B KEGG: bsu:BSU25070 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02578 BSBS38_02579 BSBS38_02579 BSBS38_02579 2388432 2388815 - uncharacterized protein gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02579 BSBS38_02580 BSBS38_02580 BSBS38_02580 2388954 2389535 + Putative nucleotidase YqfW Belongs to the 5'(3')-deoxyribonucleotidase family gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02580 BSBS38_02581 BSBS38_02581 BSBS38_02581 2389578 2390015 - Zinc-specific metallo-regulatory protein Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repression of two operons implicated in zinc uptake%2C yciC and ycdHIyceA. Also represses the expression of rpmE2%2C the gene for ribosomal protein L31B%2C which is expressed only after the end of exponential growth%3B Belongs to the Fur family gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02581 BSBS38_02582 BSBS38_02582 BSBS38_02582 2390153 2391034 - UPF0750 membrane protein YqfU Belongs to the UPF0750 family gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02582 BSBS38_02583 BSBS38_02583 BSBS38_02583 2391150 2391404 + uncharacterized protein gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02583 BSBS38_02584 BSBS38_02584 BSBS38_02584 2391431 2392324 - Deoxyribonuclease IV Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin%3B Belongs to the AP endonuclease 2 family%3B KEGG: bsu:BSU25130 deoxyribonuclease IV gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02584 BSBS38_02585 BSBS38_02585 cshB cshB 2392334 2393650 - RNA helicase DEAD-box RNA helicase that plays a role in 70S ribosome assembly. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU25140 ATP-dependent RNA helicase CshB gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02585 BSBS38_02586 BSBS38_02586 BSBS38_02586 2393819 2394562 + uncharacterized protein gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02586 BSBS38_02587 BSBS38_02587 ispH ispH 2394685 2395629 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B Belongs to the IspH family%3B KEGG: bsu:BSU25160 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02587 BSBS38_02588 BSBS38_02588 BSBS38_02588 2395652 2396773 - GTP cyclohydrolase 1 type 2 like protein Belongs to the GTP cyclohydrolase I type 2/NIF3 family gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02588 BSBS38_02589 BSBS38_02589 trmK trmK 2396766 2397416 - tRNA (adenine(22)-N(1))-methyltransferase Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 22 (m1A22) in tRNA%3B Belongs to the TrmK family%3B KEGG: ppu:PP_3495 tRNA (adenine22-N1)-methyltransferase gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02589 BSBS38_02590 BSBS38_02590 BSBS38_02590 2397673 2398035 - Cytochrome c-550 gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02590 BSBS38_02591 BSBS38_02591 BSBS38_02591 2398364 2399479 - RNA polymerase sigma factor SigA Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth%3B Belongs to the sigma-70 factor family. RpoD/SigA subfamily gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02591 BSBS38_02592 BSBS38_02592 dnaG dnaG 2399678 2401489 - DNA primase RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication%3B Belongs to the DnaG primase family%3B Contains 1 Toprim domain%3B KEGG: noc:Noc_0044 DNA primase%3B Nucleotidyltransferases gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02592 BSBS38_02593 BSBS38_02593 BSBS38_02593 2401523 2402017 - UPF0178 protein Belongs to the UPF0178 family gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02593 BSBS38_02594 BSBS38_02594 BSBS38_02594 2402271 2403083 - Putative pyruvate%2C phosphate dikinase regulatory protein Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate%2C phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation%3B Belongs to the pyruvate%2C phosphate/water dikinase regulatory protein family. PDRP subfamily gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02594 BSBS38_02595 BSBS38_02595 BSBS38_02595 2403109 2403750 - Transcriptional repressor CcpN Transcription repressor that binds to the promoter of gapB and pckA genes%2C preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes%3B Contains 2 CBS domains%3B Contains 1 HTH deoR-type DNA-binding domain gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02595 BSBS38_02596 BSBS38_02596 glyS glyS 2403880 2405919 - Glycine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: ilo:IL0005 glycyl-tRNA synthetase beta chain%3B overlaps another CDS with the same product name gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02596 BSBS38_02597 BSBS38_02597 glyQ glyQ 2405912 2406799 - Glycine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: wbr:WGLp593 glycyl-tRNA synthetase alpha chain%3B overlaps another CDS with the same product name gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02597 BSBS38_02598 BSBS38_02598 BSBS38_02598 2407096 2407863 - DNA repair protein RecO Involved in DNA repair and RecF pathway recombination%3B Belongs to the RecO family gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02598 BSBS38_02599 BSBS38_02599 BSBS38_02599 2407900 2408043 - uncharacterized protein gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02599 BSBS38_02600 BSBS38_02600 BSBS38_02600 2408191 2409096 - GTPase Era An essential GTPase that binds both GDP and GTP%2C with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity). Binds both GDP and GTP. Complements an E. coli era disruption mutant%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Era GTPase family%3B Contains 1 Era-type G (guanine nucleotide-binding) domain%3B Contains 1 KH type-2 domain gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02600 BSBS38_02601 BSBS38_02601 BSBS38_02601 2409077 2409487 - Cytidine deaminase This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bsu:BSU25300 cytidine deaminase gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02601 BSBS38_02602 BSBS38_02602 BSBS38_02602 2409606 2409977 - Undecaprenol kinase Catalyzes the phosphorylation of undecaprenol in vitro%2C which is probably the physiological substrate. Exhibits no detectable activity against other substrates such as monoacylglycerol%2C ceramide%2C or diacylglycerol (DAG). Appears indispensable for the maintenance of spore stability and viability in B. subtilis%3B Belongs to the bacterial diacylglycerol kinase family%3B KEGG: bsu:BSU25310 undecaprenol kinase gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02602 BSBS38_02603 BSBS38_02603 BSBS38_02603 2409958 2410431 - Endoribonuclease YbeY Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA%3B Belongs to the endoribonuclease YbeY family gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02603 BSBS38_02604 BSBS38_02604 BSBS38_02604 2410432 2412567 - uncharacterized protein gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02604 BSBS38_02605 BSBS38_02605 BSBS38_02605 2412548 2412646 - hypothetical protein gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02605 BSBS38_02606 BSBS38_02606 BSBS38_02606 2412646 2413605 - PhoH-like protein Belongs to the PhoH family gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02606 BSBS38_02607 BSBS38_02607 BSBS38_02607 2413602 2414798 - uncharacterized protein To B. megaterium SpoIV gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02607 BSBS38_02608 BSBS38_02608 BSBS38_02608 2414817 2415098 - uncharacterized protein gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02608 BSBS38_02609 BSBS38_02609 BSBS38_02609 2415155 2415574 - uncharacterized protein gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02609 BSBS38_02610 BSBS38_02610 BSBS38_02610 2415599 2416594 - UPF0365 protein Belongs to the UPF0365 family gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02610 BSBS38_02611 BSBS38_02611 BSBS38_02611 2416616 2417677 - uncharacterized protein overlaps another CDS with the same product name gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02611 BSBS38_02612 BSBS38_02612 BSBS38_02612 2417674 2417928 - uncharacterized protein overlaps another CDS with the same product name gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02612 BSBS38_02613 BSBS38_02613 BSBS38_02613 2418059 2418505 - uncharacterized protein gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02613 BSBS38_02614 BSBS38_02614 BSBS38_02614 2418520 2418693 - 30S ribosomal protein S21 Belongs to the ribosomal protein S21P family gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02614 BSBS38_02615 BSBS38_02615 BSBS38_02615 2418857 2419789 + uncharacterized protein To E. coli YjbB gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02615 BSBS38_02616 BSBS38_02616 mtaB mtaB 2419825 2421180 - tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A)%2C leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine%3B Belongs to the methylthiotransferase family. MtaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU25430 threonylcarbamoyladenosine tRNA methylthiotransferase MtaB gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02616 BSBS38_02617 BSBS38_02617 rsmE rsmE 2421180 2421950 - 16S rRNA (uracil(1498)-N(3))-methyltransferase Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)%3B Belongs to the RNA methyltransferase RsmE family%3B KEGG: bsu:BSU25440 16S rRNA (uracil1498-N3)-methyltransferase gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02617 BSBS38_02618 BSBS38_02618 prmA prmA 2421973 2422908 - Ribosomal protein L11 methyltransferase Methylates ribosomal protein L11%3B Belongs to the methyltransferase superfamily. PrmA family%3B KEGG: bsu:BSU25450 ribosomal protein L11 methyltransferase%3B Methyltransferases gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02618 BSBS38_02619 BSBS38_02619 BSBS38_02619 2422933 2424060 - Chaperone protein DnaJ Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C DnaK-independent fashion. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding. Also involved%2C together with DnaK and GrpE%2C in the DNA replication of plasmids through activation of initiation proteins%3B Belongs to the DnaJ family%3B Contains 1 CR-type zinc finger%3B Contains 1 J domain gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02619 BSBS38_02620 BSBS38_02620 BSBS38_02620 2424260 2426095 - Chaperone protein DnaK Acts as a chaperone%3B Belongs to the heat shock protein 70 family gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02620 BSBS38_02621 BSBS38_02621 BSBS38_02621 2426119 2426682 - Protein GrpE Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%2C in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP- dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding%3B Belongs to the GrpE family gene gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02621 BSBS38_02622 BSBS38_02622 BSBS38_02622 2426754 2427785 - Heat-inducible transcription repressor HrcA Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons%3B Belongs to the HrcA family gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02622 BSBS38_02623 BSBS38_02623 BSBS38_02623 2427866 2429005 - Coproporphyrinogen dehydrogenase Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemN-like subfamily%3B KEGG: bsu:BSU25500 oxygen-independent coproporphyrinogen III oxidase gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02623 BSBS38_02624 BSBS38_02624 BSBS38_02624 2429059 2430897 - Elongation factor Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction%2C by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex%2C thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02624 BSBS38_02625 BSBS38_02625 BSBS38_02625 2431031 2431369 - uncharacterized protein gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02625 BSBS38_02626 BSBS38_02626 BSBS38_02626 2431386 2432591 - Stage II sporulation protein gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02626 BSBS38_02627 BSBS38_02627 BSBS38_02627 2432654 2433760 - GPR endopeptidase Initiates the degradation of small%2C acid-soluble proteins during spore germination. Belongs to the peptidase A25 family%3B KEGG: bsu:BSU25540 spore protease gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02627 BSBS38_02628 BSBS38_02628 BSBS38_02628 2433964 2434230 + 30S ribosomal protein S20 Binds directly to 16S ribosomal RNA%3B Belongs to the ribosomal protein S20P family gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02628 BSBS38_02629 BSBS38_02629 holA holA 2434245 2435288 - DNA-directed DNA polymerase KEGG: bsu:BSU25560 DNA polymerase III subunit delta gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02629 BSBS38_02630 BSBS38_02630 BSBS38_02630 2435518 2435652 + putative membrane protein YqzM gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02630 BSBS38_02631 BSBS38_02631 BSBS38_02631 2435693 2438023 - ComE operon protein The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding. To H. influenzae REC2%2C N. gonorrhoeae ComA and E. coli YcaI gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02631 BSBS38_02632 BSBS38_02632 BSBS38_02632 2438027 2438596 - dCMP deaminase Dispensable for transformability. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bsu:BSU25580 dCMP deaminase gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02632 BSBS38_02633 BSBS38_02633 BSBS38_02633 2438663 2439280 - ComE operon protein Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect. Contains 2 HhH domains gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02633 BSBS38_02634 BSBS38_02634 BSBS38_02634 2439364 2440185 + ComE operon protein Dispensable for transformability. Not known if it can act as a pyrroline-5-carboxylate reductase. Belongs to the pyrroline-5-carboxylate reductase family gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02634 BSBS38_02635 BSBS38_02635 BSBS38_02635 2440251 2440994 - Cyclopropane-fatty-acyl-phospholipid synthase May be a S-adenosyl-L-methionine (SAM)-dependent methyltransferase. Belongs to the methyltransferase superfamily%3B KEGG: psf:PSE_4519 cyclopropane-fatty-acyl-phospholipid synthase gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02635 BSBS38_02636 BSBS38_02636 BSBS38_02636 2440991 2441347 - Ribosomal silencing factor RsfS Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN)%2C blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes%2C thus repressing translation%3B Belongs to the Iojap/RsfS family gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02636 BSBS38_02637 BSBS38_02637 nadD nadD 2441365 2441925 - Nicotinate-nucleotide adenylyltransferase Contains 1 HD domain%3B KEGG: ccel:CCDG5_0474 nicotinate-nucleotide adenylyltransferase%3B overlaps another CDS with the same product name gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02637 BSBS38_02638 BSBS38_02638 BSBS38_02638 2441915 2442484 - Nicotinate-nucleotide adenylyltransferase Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)%3B Belongs to the NadD family%3B KEGG: nma:NMA0416 nicotinate-nucleotide adenylyltransferase%3B overlaps another CDS with the same product name gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02638 BSBS38_02639 BSBS38_02639 BSBS38_02639 2442496 2442786 - putative RNA-binding protein YqeI Contains 1 CRM domain gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02639 BSBS38_02640 BSBS38_02640 aroE aroE 2442780 2443622 - Shikimate dehydrogenase Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: bsu:BSU25660 shikimate dehydrogenase gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02640 BSBS38_02641 BSBS38_02641 BSBS38_02641 2443640 2444740 - uncharacterized protein Binds GTP and GDP. Belongs to the TRAFAC class YlqF/YawG GTPase family%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02641 BSBS38_02642 BSBS38_02642 BSBS38_02642 2444744 2445271 - uncharacterized protein gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02642 BSBS38_02643 BSBS38_02643 BSBS38_02643 2445903 2445995 - hypothetical protein gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02643 BSBS38_02644 BSBS38_02644 BSBS38_02644 2446070 2446801 - putative lipoprotein YqeF gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02644 BSBS38_02645 BSBS38_02645 BSBS38_02645 2447053 2447805 - N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation. Could play a role in mother cell lysis with CwlC. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bsu:BSU25710 N-acetylmuramoyl-L-alanine amidase gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02645 BSBS38_02646 BSBS38_02646 BSBS38_02646 2447992 2448618 + uncharacterized protein gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02646 BSBS38_02647 BSBS38_02647 BSBS38_02647 2448638 2449021 - Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NAD to NADH%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: dpr:Despr_2153 6-phosphogluconate dehydrogenase gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02647 BSBS38_02648 BSBS38_02648 BSBS38_02648 2449024 2449530 - Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NAD to NADH%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: pam:PANA_4019 6-phosphogluconate dehydrogenase gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02648 BSBS38_02649 BSBS38_02649 BSBS38_02649 2449785 2450504 + uncharacterized protein gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02649 BSBS38_02650 BSBS38_02650 BSBS38_02650 2450537 2450947 - Sporulation-specific extracellular nuclease Degrades both double-stranded linear and covalently closed circular DNA. Likely to play a scavenging role in order to supply nutrients under starvation conditions. To B. subtilis NucA/ComI gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02650 BSBS38_02651 BSBS38_02651 BSBS38_02651 2451143 2451574 + RNA polymerase sigma-K factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the mother cell. Belongs to the sigma-70 factor family gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02651 BSBS38_02652 BSBS38_02652 BSBS38_02652 2451589 2451870 + RNA polymerase sigma-K factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the mother cell. Belongs to the sigma-70 factor family gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02652 BSBS38_02653 BSBS38_02653 fumC fumC 2452396 2453784 - Fumarate hydratase Catalyzes the reversible addition of water to fumarate to give L-malate%3B Belongs to the class-II fumarase/aspartase family. Fumarase subfamily%3B KEGG: hin:HI1398 fumarate hydratase%2C class II gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02653 BSBS38_02654 BSBS38_02654 BSBS38_02654 2453951 2454841 + putative HTH-type transcriptional regulator YybE Contains 1 HTH lysR-type DNA-binding domain gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02654 BSBS38_02655 BSBS38_02655 BSBS38_02655 2455782 2456177 + hypothetical protein gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02655 BSBS38_02656 BSBS38_02656 BSBS38_02656 2456799 2456927 - hypothetical protein gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02656 BSBS38_02657 BSBS38_02657 BSBS38_02657 2456917 2458044 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsr:I33_2680 response regulator aspartate phosphatase H%3B Acting on ester bonds gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02657 BSBS38_02658 BSBS38_02658 BSBS38_02658 2458306 2458407 + Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02658 BSBS38_02659 BSBS38_02659 BSBS38_02659 2458444 2459484 + Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02659 BSBS38_02660 BSBS38_02660 BSBS38_02660 2459481 2460152 + hypothetical protein gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02660 BSBS38_02661 BSBS38_02661 BSBS38_02661 2460166 2460453 + hypothetical protein gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02661 BSBS38_02662 BSBS38_02662 BSBS38_02662 2460856 2461296 + hypothetical protein gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02662 BSBS38_02663 BSBS38_02663 BSBS38_02663 2461395 2461622 + hypothetical protein gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02663 BSBS38_02664 BSBS38_02664 BSBS38_02664 2461945 2462304 + hypothetical protein gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02664 BSBS38_02665 BSBS38_02665 BSBS38_02665 2462409 2462888 + hypothetical protein gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02665 BSBS38_02666 BSBS38_02666 BSBS38_02666 2462997 2463173 + hypothetical protein gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02666 BSBS38_02667 BSBS38_02667 BSBS38_02667 2463334 2464881 + Transposase for insertion sequence element IS21-like protein Involved in the transposition of the insertion sequence%3B Belongs to the transposase IS21/IS408/IS1162 family%3B Contains 1 HTH IS21-type DNA-binding domain%3B Contains 1 integrase catalytic domain gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02667 BSBS38_02668 BSBS38_02668 BSBS38_02668 2464878 2465636 + Insertion sequence IS21 putative ATP-binding protein One of two proteins expressed only when there is a tandem repeat of the IS21 insertion sequence%2C it is necessary for the transposition of plasmids with that tandem repeat. Belongs to the IS21/IS1162 putative ATP-binding protein family gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02668 BSBS38_02669 BSBS38_02669 BSBS38_02669 2465569 2465853 - hypothetical protein gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02669 BSBS38_02670 BSBS38_02670 BSBS38_02670 2465972 2466205 + hypothetical protein gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02670 BSBS38_02671 BSBS38_02671 BSBS38_02671 2466838 2467050 + Antitoxin YqcF Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the RNase activity of cognate toxin YqcG%2C as well as its ability to inhibit growth upon expression in E. coli. Does not have antitoxin activity on other toxins with the LXG toxin domain gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02671 BSBS38_02672 BSBS38_02672 BSBS38_02672 2467160 2467450 + hypothetical protein gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02672 BSBS38_02673 BSBS38_02673 BSBS38_02673 2468364 2468543 - hypothetical protein gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02673 BSBS38_02674 BSBS38_02674 BSBS38_02674 2469087 2469548 - Phage-like element PBSX protein XkdM To B. subtilis YqbM gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02674 BSBS38_02675 BSBS38_02675 BSBS38_02675 2469947 2470072 - hypothetical protein gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02675 BSBS38_02676 BSBS38_02676 BSBS38_02676 2470897 2471286 - hypothetical protein gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02676 BSBS38_02677 BSBS38_02677 BSBS38_02677 2471538 2471645 - hypothetical protein gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02677 BSBS38_02678 BSBS38_02678 BSBS38_02678 2471989 2472258 + hypothetical protein gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02678 BSBS38_02679 BSBS38_02679 BSBS38_02679 2473285 2473515 - hypothetical protein gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02679 BSBS38_02680 BSBS38_02680 BSBS38_02680 2473593 2473829 - hypothetical protein gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02680 BSBS38_02681 BSBS38_02681 BSBS38_02681 2474037 2474858 - Multidrug-efflux transporter 2 regulator Activates transcription of the blt gene in response to structurally dissimilar drugs. Contains 1 HTH merR-type DNA-binding domain gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02681 BSBS38_02682 BSBS38_02682 BSBS38_02682 2474975 2476177 + Multidrug resistance protein Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances%2C including such structurally diverse compounds as ethidium bromide%2C rhodamine and acridine dyes%2C tetraphenylphosphonium%2C puromycin%2C chloramphenicol%2C doxorubicin%2C and fluoroquinolone antibiotics. Belongs to the major facilitator superfamily. TCR/Tet family gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02682 BSBS38_02683 BSBS38_02683 BSBS38_02683 2476346 2476804 + Diamine N-acetyltransferase Acetylates both spermidine and spermine at primary propyl amine moieties%2C with spermine being the preferred substrate%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsl:A7A1_0807 diamine N-acetyltransferase gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02683 BSBS38_02684 BSBS38_02684 BSBS38_02684 2476953 2478257 - UPF0053 protein YrkA Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02684 BSBS38_02685 BSBS38_02685 BSBS38_02685 2478547 2478690 - uncharacterized protein gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02685 BSBS38_02686 BSBS38_02686 BSBS38_02686 2478708 2479673 - putative transporter YrdR Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02686 BSBS38_02687 BSBS38_02687 BSBS38_02687 2479799 2480665 + HTH-type transcriptional regulator CfxR Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression. Contains 1 HTH lysR-type DNA-binding domain gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02687 BSBS38_02688 BSBS38_02688 BSBS38_02688 2480786 2481823 - putative oxidoreductase CzcO Involved in potassium and divalent cation transport. Enhances the transport activity of the cation/potassium transporter CzcD (By similarity) gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02688 BSBS38_02689 BSBS38_02689 BSBS38_02689 2481911 2482846 - Cadmium%2C cobalt and zinc/H(+)-K(+) antiporter Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc%2C cadmium and cobalt%2C in exchange for potassium and H(+) ions%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family. SLC30A subfamily gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02689 BSBS38_02690 BSBS38_02690 BSBS38_02690 2483065 2483271 + hypothetical protein gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02690 BSBS38_02691 BSBS38_02691 BSBS38_02691 2483524 2484846 - Branched-chain amino acid transport system carrier protein BrnQ Component of the transport system for branched-chain amino acids (leucine%2C isoleucine and valine) Which is coupled to a proton motive force%3B Belongs to the branched chain amino acid transporter family gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02691 BSBS38_02692 BSBS38_02692 BSBS38_02692 2485011 2485343 - uncharacterized protein Belongs to the AzlD/HI_1737/HP1330 family gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02692 BSBS38_02693 BSBS38_02693 BSBS38_02693 2485340 2486104 - Branched-chain amino acid transport protein AzlC Involved in branched-chain amino acid transport. Belongs to the AzlC family gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02693 BSBS38_02694 BSBS38_02694 BSBS38_02694 2486117 2486590 - Transcriptional regulator AzlB Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport. Contains 1 HTH asnC-type DNA-binding domain gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02694 BSBS38_02695 BSBS38_02695 BSBS38_02695 2486924 2487199 - Putative ribonuclease inhibitor YrdF Belongs to the barstar family gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02695 BSBS38_02696 BSBS38_02696 BSBS38_02696 2487472 2488704 - Cytochrome P450 Belongs to the cytochrome P450 family%3B KEGG: ban:BA_2627 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02696 BSBS38_02697 BSBS38_02697 frmA frmA 2489156 2489887 + S-(hydroxymethyl)glutathione dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: bsu:BSU26970 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02697 BSBS38_02698 BSBS38_02698 BSBS38_02698 2489906 2490103 + uncharacterized protein gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02698 BSBS38_02699 BSBS38_02699 BSBS38_02699 2490119 2490418 + Spore coat protein F-like protein YraD Belongs to the CotF family gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02699 BSBS38_02700 BSBS38_02700 BSBS38_02700 2490524 2490808 - hypothetical protein gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02700 BSBS38_02701 BSBS38_02701 BSBS38_02701 2490840 2491820 - Aryl-alcohol dehydrogenase (NADP(+)) Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: fal:FRAAL3972 aryl-alcohol dehydrogenase (NADP+) gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02701 BSBS38_02702 BSBS38_02702 BSBS38_02702 2491983 2492888 + putative HTH-type transcriptional regulator YqhC Contains 1 HTH araC/xylS-type DNA-binding domain gene gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02702 BSBS38_02703 BSBS38_02703 BSBS38_02703 2492911 2493066 - hypothetical protein gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02703 BSBS38_02704 BSBS38_02704 BSBS38_02704 2493014 2493238 - hypothetical protein gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02704 BSBS38_02705 BSBS38_02705 BSBS38_02705 2493514 2493936 - HTH-type transcriptional regulator AdhR Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon%2C the yraC and its own promoter regio%3B binding is unchanged in the presence of aldehydes%3B Contains 1 HTH merR-type DNA-binding domain gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02705 BSBS38_02706 BSBS38_02706 pcaC pcaC 2494118 2494852 + 4-carboxymuconolactone decarboxylase KEGG: bsy:I653_12810 4-carboxymuconolactone decarboxylase gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02706 BSBS38_02707 BSBS38_02707 yahK yahK 2494999 2496048 + putative formaldehyde dehydrogenase AdhA Functions in the protection against aldehyde-stress%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU27010 uncharacterized zinc-type alcohol dehydrogenase-like protein%3B Oxidoreductases gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02707 BSBS38_02708 BSBS38_02708 BSBS38_02708 2496181 2496690 + General stress protein Functions in the protection against aldehyde-stress%2C possibly by degrading damaged proteins%3B Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: eco:b3153 protease I%3B Glycosylases gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02708 BSBS38_02709 BSBS38_02709 fruA fruA 2496734 2498767 - Fructan beta-fructosidase Exo-fructosidase that can hydrolyze both levan and inulin%2C leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose%2C but not melezitose%2C stachylose%2C cellobiose%2C maltose%2C and lactose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bsu:BSU27030 fructan beta-fructosidase gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02709 BSBS38_02710 BSBS38_02710 BSBS38_02710 2498924 2499751 - Fructose permease IID component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport. Contains 1 PTS EIID domain gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02710 BSBS38_02711 BSBS38_02711 BSBS38_02711 2499773 2500579 - Fructose permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport. Contains 1 PTS EIIC type-4 domain gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02711 BSBS38_02712 BSBS38_02712 levE levE 2500596 2501084 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. LevD and LevE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator. Contains 1 PTS EIIB type-4 domain%3B KEGG: kox:KOX_13535 PTS system%2C fructose-specific IIB component%3B overlaps another CDS with the same product name gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02712 BSBS38_02713 BSBS38_02713 agaF agaF 2501084 2501524 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. LevD and LevE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator. Contains 1 PTS EIIA type-4 domain%3B KEGG: ece:Z4488 PTS system%2C N-acetylgalactosamine-specific IIA component%3B overlaps another CDS with the same product name gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02713 BSBS38_02714 BSBS38_02714 BSBS38_02714 2501714 2504530 - Transcriptional regulatory protein LevR Involved in positive regulation of the levanase operon which comprises the levDEFG genes for a fructose PTS system%2C and sacA for levanase. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-4 domain%3B Contains 1 sigma-54 factor interaction domain gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02714 BSBS38_02715 BSBS38_02715 BSBS38_02715 2505257 2506645 + Amino-acid permease AapA Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02715 BSBS38_02716 BSBS38_02716 BSBS38_02716 2506779 2508131 + hypothetical protein gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02716 BSBS38_02717 BSBS38_02717 BSBS38_02717 2508136 2508345 + hypothetical protein gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02717 BSBS38_02718 BSBS38_02718 BSBS38_02718 2508326 2508958 - putative membrane protein YrhP Belongs to the rht family gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02718 BSBS38_02719 BSBS38_02719 BSBS38_02719 2509113 2509940 + Cadmium-exporting ATPase KEGG: cau:Caur_3747 Cd2+/Zn2+-exporting ATPase gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02719 BSBS38_02720 BSBS38_02720 BSBS38_02720 2510134 2510634 + RNA polymerase sigma factor SigV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin%2C paraquat and tellurite%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02720 BSBS38_02721 BSBS38_02721 BSBS38_02721 2510634 2511491 + Anti-sigma-V factor RsiV Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02721 BSBS38_02722 BSBS38_02722 BSBS38_02722 2511600 2513504 + Putative peptidoglycan O-acetyltransferase YrhL Belongs to the acyltransferase 3 family%3B KEGG: mtu:Rv0111 null%3B Transferring groups other than amino-acyl groups gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02722 BSBS38_02723 BSBS38_02723 BSBS38_02723 2513635 2513928 + uncharacterized protein gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02723 BSBS38_02724 BSBS38_02724 BSBS38_02724 2514172 2517336 - Unspecific monooxygenase Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of medium to long-chain fatty acids%2C with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 and omega-3 positions%2C in approximately equal proportions. Also displays a NADPH-dependent reductase activity in the C-terminal domain%2C which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N- terminal domain%3B In the N-terminal sectio%3B belongs to the cytochrome P450 family%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bsu:BSU27160 cytochrome P450 / NADPH-cytochrome P450 reductase gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02724 BSBS38_02725 BSBS38_02725 BSBS38_02725 2517352 2517936 - HTH-type transcriptional repressor FatR Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate%2C linoleate and phytanate%2C thereby allowing transcription of the fatR-cypB operon%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02725 BSBS38_02726 BSBS38_02726 BSBS38_02726 2518159 2518701 - Putative methyltransferase YrhH Belongs to the methyltransferase superfamily gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02726 BSBS38_02727 BSBS38_02727 BSBS38_02727 2519204 2519353 - uncharacterized protein gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02727 BSBS38_02728 BSBS38_02728 BSBS38_02728 2519741 2520541 - putative transporter YrhG Belongs to the FNT transporter (TC 2. A. 44) family gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02728 BSBS38_02729 BSBS38_02729 BSBS38_02729 2520578 2520733 - hypothetical protein gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02729 BSBS38_02730 BSBS38_02730 BSBS38_02730 2520803 2521171 - uncharacterized protein gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02730 BSBS38_02731 BSBS38_02731 BSBS38_02731 2521481 2524429 + Formate dehydrogenase In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsr:I33_2764 formate dehydrogenase major subunit gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02731 BSBS38_02732 BSBS38_02732 BSBS38_02732 2524448 2524930 + uncharacterized protein To A. fulgidus AF1717 gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02732 BSBS38_02733 BSBS38_02733 BSBS38_02733 2524967 2525197 - uncharacterized protein gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02733 BSBS38_02734 BSBS38_02734 mccB mccB 2525280 2526419 - Cystathionine gamma-lyase Catalyzes the conversion of cystathionine to cysteine%2C and homocysteine to sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bsu:BSU27250 cystathionine gamma-lyase / homocysteine desulfhydrase gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02734 BSBS38_02735 BSBS38_02735 BSBS38_02735 2526421 2527344 - Cysteine synthase Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: dat:HRM2_06910 cysteine synthase A gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02735 BSBS38_02736 BSBS38_02736 mtnN mtnN 2527409 2528104 - Adenosylhomocysteine nucleosidase Catalyzes the direct conversion of aminodeoxyfutalosine (AFL) into dehypoxanthine futalosine (DHFL) and adenine via the hydrolysis of the N-glycosidic bon%3B this reaction seems to represent an essential step in the menaquinone biosynthesis pathway in Campylobacter species. Also catalyzes the hydrolysis of 5'-methylthioadenosine (MTA) to adenine and 5'-methylthioribose. Can also probably use S-adenosylhomocysteine (SAH) as substrate%2C leading to adenine and S-ribosylhomocysteine. These other activities highlight the tremendous versatility of the enzyme%2C which also plays key roles in S-adenosylmethionine recycling and in the biosynthesis of the quorum-sensing molecule autoinducer-2. Shows negligible activity with futalosine (FL) as substrate%3B Belongs to the PNP/UDP phosphorylase family%3B KEGG: pat:Patl_0518 adenosylhomocysteine nucleosidase gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02736 BSBS38_02737 BSBS38_02737 yrrT yrrT 2528125 2528766 - putative methyltransferase Could be a S-adenosyl-L-methionine-dependent methyltransferase%3B Belongs to the methyltransferase superfamily. YrrT family%3B KEGG: bsu:BSU27280 putative AdoMet-dependent methyltransferase%3B Methyltransferases gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02737 BSBS38_02738 BSBS38_02738 BSBS38_02738 2528959 2529162 + uncharacterized protein gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02738 BSBS38_02739 BSBS38_02739 BSBS38_02739 2529199 2529900 - putative membrane protein YrrS gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02739 BSBS38_02740 BSBS38_02740 BSBS38_02740 2529965 2531719 - Peptidoglycan glycosyltransferase Penicillin-binding protein with an unknown catalytic activity. Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family%3B KEGG: cth:Cthe_1011 peptidoglycan glycosyltransferase gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02740 BSBS38_02741 BSBS38_02741 BSBS38_02741 2531773 2532246 - Transcription elongation factor GreA Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides%3B Belongs to the GreA/GreB family gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02741 BSBS38_02742 BSBS38_02742 BSBS38_02742 2532497 2533132 - Uridine kinase Involved in the pyrimidine salvage pathway. The uracil phosphoribosyltransferase (UPRT) activity%2C that catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate%2C is unsure%3B In the N-terminal sectio%3B belongs to the uridine kinase family%3B In the C-terminal sectio%3B belongs to the UPRTase family%3B KEGG: bsu:BSU27330 uridine kinase gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02742 BSBS38_02743 BSBS38_02743 BSBS38_02743 2533139 2534407 - putative protease YrrO Belongs to the peptidase U32 family%3B KEGG: bsu:BSU27340 putative protease%3B Acting on peptide bonds (peptidases) gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02743 BSBS38_02744 BSBS38_02744 BSBS38_02744 2534426 2535355 - putative protease YrrN Belongs to the peptidase U32 family%3B KEGG: bsu:BSU27350 putative protease%3B Acting on peptide bonds (peptidases) gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02744 BSBS38_02745 BSBS38_02745 BSBS38_02745 2535361 2536014 - Caffeoyl-CoA O-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family%3B KEGG: bce:BC4378 caffeoyl-CoA O-methyltransferase gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02745 BSBS38_02746 BSBS38_02746 BSBS38_02746 2536166 2537248 - UPF0755 protein YrrL Belongs to the UPF0755 family gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02746 BSBS38_02747 BSBS38_02747 BSBS38_02747 2537379 2537660 - UPF0473 protein Belongs to the UPF0473 family gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02747 BSBS38_02748 BSBS38_02748 ruvX ruvX 2537678 2538094 - Putative pre-16S rRNA nuclease Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA%3B Belongs to the YqgF nuclease family%3B KEGG: dao:Desac_2916 putative holliday junction resolvase%3B Acting on ester bonds gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02748 BSBS38_02749 BSBS38_02749 BSBS38_02749 2538102 2538368 - UPF0297 protein Belongs to the UPF0297 family%3B KEGG: snu:SPNA45_01835 putative holliday junction resolvase%3B Acting on ester bonds gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02749 BSBS38_02750 BSBS38_02750 aarS aarS 2538453 2541089 - Alanine--tRNA ligase Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pha:PSHAa0532 alanyl-tRNA synthetase gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02750 BSBS38_02751 BSBS38_02751 BSBS38_02751 2541420 2542481 - UPF0118 membrane protein YrrI Belongs to the UPF0118 (PerM) family gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02751 BSBS38_02752 BSBS38_02752 BSBS38_02752 2542637 2543365 + Glutamine transport ATP-binding protein GlnQ Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02752 BSBS38_02753 BSBS38_02753 BSBS38_02753 2543386 2544207 + ABC transporter glutamine-binding protein GlnH Part of the ABC transporter complex GlnHMPQ involved in glutamine transport%3B Belongs to the bacterial solute-binding protein 3 family gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02753 BSBS38_02754 BSBS38_02754 BSBS38_02754 2544268 2544918 + putative glutamine ABC transporter permease protein GlnM Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02754 BSBS38_02755 BSBS38_02755 BSBS38_02755 2544935 2545591 + putative glutamine ABC transporter permease protein GlnP Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02755 BSBS38_02756 BSBS38_02756 BSBS38_02756 2545626 2545757 - uncharacterized protein gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02756 BSBS38_02757 BSBS38_02757 BSBS38_02757 2545779 2545970 - uncharacterized protein gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02757 BSBS38_02758 BSBS38_02758 BSBS38_02758 2545982 2546446 - uncharacterized protein gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02758 BSBS38_02759 BSBS38_02759 recD recD 2546563 2548959 - Exodeoxyribonuclease V DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs%2C requires at least 10 bases of 5'-ssDNA for helicase activity%3B Belongs to the RecD family. RecD-like subfamily%3B KEGG: bsu:BSU27480 exodeoxyribonuclease V alpha subunit gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02759 BSBS38_02760 BSBS38_02760 BSBS38_02760 2548984 2549634 - TPR repeat-containing protein YrrB Could be an interacting mediator in the complex formation among RNA sulfuration components%2C RNA processing components%2C and aminoacyl-tRNA synthetases. Contains 6 TPR repeats gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02760 BSBS38_02761 BSBS38_02761 mnmA mnmA 2549690 2550805 - tRNA-specific 2-thiouridylase MnmA Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA%2C leading to the formation of s(2)U34%3B Belongs to the MnmA/TRMU family%3B KEGG: azl:AZL_020120 tRNA-specific 2-thiouridylase%3B Sulfurtransferases gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02761 BSBS38_02762 BSBS38_02762 BSBS38_02762 2550836 2551975 - Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: tti:THITH_16475 cysteine desulfurase gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02762 BSBS38_02763 BSBS38_02763 BSBS38_02763 2551994 2552413 - HTH-type transcriptional regulator CymR Master repressor of cysteine metabolism in B. subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK)%2C sulfonates (ssu)%2C or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulated by CysK in response to cysteine availability. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02763 BSBS38_02764 BSBS38_02764 BSBS38_02764 2552613 2553878 + putative AAA domain-containing protein YrvN Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02764 BSBS38_02765 BSBS38_02765 BSBS38_02765 2553918 2554682 - tRNA threonylcarbamoyladenosine dehydratase Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine%3B Belongs to the HesA/MoeB/ThiF family gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02765 BSBS38_02766 BSBS38_02766 darS darS 2555017 2556795 - Aspartate--tRNA ligase Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU27550 aspartyl-tRNA synthetase gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02766 BSBS38_02767 BSBS38_02767 harS harS 2556809 2558083 - Histidine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU27560 histidyl-tRNA synthetase gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02767 BSBS38_02768 BSBS38_02768 BSBS38_02768 2558465 2558635 - uncharacterized protein gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02768 BSBS38_02769 BSBS38_02769 BSBS38_02769 2558768 2560324 + N-acetylmuramoyl-L-alanine amidase Probably involved in cell-wall metabolism%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bsu:BSU27580 N-acetylmuramoyl-L-alanine amidase gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02769 BSBS38_02770 BSBS38_02770 dtd1 dtd1 2560351 2560791 - D-aminoacyl-tRNA deacylase D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules%2C this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo%3B Belongs to the DTD family%3B KEGG: sml:Smlt4166 D-tyrosyl-tRNA(Tyr) deacylase%3B Acting on ester bonds gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02770 BSBS38_02771 BSBS38_02771 relA relA 2560804 2563008 - GTP diphosphokinase In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity)%3B Belongs to the RelA/SpoT family%3B Contains 1 ACT domain%3B Contains 1 HD domain%3B KEGG: bsu:BSU27600 GTP pyrophosphokinase gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02771 BSBS38_02772 BSBS38_02772 aprT aprT 2563176 2563688 - Adenine phosphoribosyltransferase Catalyzes a salvage reaction resulting in the formation of AMP%2C that is energically less costly than de novo synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: goh:B932_1344 adenine phosphoribosyltransferase gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02772 BSBS38_02773 BSBS38_02773 recJ recJ 2563694 2566054 - Single-stranded-DNA-specific exonuclease RecJ Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB%3B Belongs to the RecJ family%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU27620 single-stranded-DNA-specific exonuclease%3B Acting on ester bonds gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02773 BSBS38_02774 BSBS38_02774 BSBS38_02774 2566121 2566444 - uncharacterized protein gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02774 BSBS38_02775 BSBS38_02775 BSBS38_02775 2566520 2567017 - K(+)/H(+) antiporter subunit KhtT Modulates the activity of the potassium/proton antiporter YhaU. The transporter is composed of the integral membrane protein YhaU and the regulatory protein KhtT%3B Contains 1 RCK C-terminal domain gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02775 BSBS38_02776 BSBS38_02776 BSBS38_02776 2567175 2569388 - Protein translocase subunit SecDF Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)%3B In the N-terminal sectio%3B belongs to the SecD/SecF family. SecD subfamily%3B In the C-terminal sectio%3B belongs to the SecD/SecF family. SecF subfamily gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02776 BSBS38_02777 BSBS38_02777 BSBS38_02777 2569427 2569723 - Post-transcriptional regulator ComN Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02777 BSBS38_02778 BSBS38_02778 BSBS38_02778 2569839 2571395 + Stage V sporulation protein Involved%2C directly or indirectly%2C in spore cortex biosynthesis. Affects only indirectly the expression of late sporulation genes. Belongs to the polysaccharide synthase family gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02778 BSBS38_02779 BSBS38_02779 BSBS38_02779 2571399 2572055 - UPF0702 transmembrane protein YrbG Belongs to the UPF0702 family gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02779 BSBS38_02780 BSBS38_02780 BSBS38_02780 2572190 2572642 + putative membrane protein YrzE gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02780 BSBS38_02781 BSBS38_02781 BSBS38_02781 2572699 2572968 - UPF0092 membrane protein YrbF Belongs to the UPF0092 family gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02781 BSBS38_02782 BSBS38_02782 BSBS38_02782 2573002 2574147 - tRNA-guanine(34) transglycosylase Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr). After this exchange%2C a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine%2C resulting in the hypermodified nucleoside queuosine (Q) (7-(((4%2C5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)%3B Belongs to the queuine tRNA-ribosyltransferase family%3B KEGG: bsu:BSU27710 queuine tRNA-ribosyltransferase gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02782 BSBS38_02783 BSBS38_02783 queA queA 2574174 2575202 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)%3B Belongs to the QueA family%3B KEGG: atu:Atu1678 S-adenosylmethionine:tRNA ribosyltransferase-isomerase gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02783 BSBS38_02784 BSBS38_02784 ruvB ruvB 2575232 2575432 - DNA helicase KEGG: bamp:B938_12840 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02784 BSBS38_02785 BSBS38_02785 BSBS38_02785 2575425 2576429 - DNA helicase RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing%3B Belongs to the RuvB family%3B KEGG: bsu:BSU27730 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02785 BSBS38_02786 BSBS38_02786 ruvA ruvA 2576440 2577045 - DNA helicase RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates%2C in the presence of DNA%2C the weak ATPase activity of RuvB%3B Belongs to the RuvA family%3B KEGG: bsu:BSU27740 holliday junction DNA helicase RuvA gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02786 BSBS38_02787 BSBS38_02787 BSBS38_02787 2577184 2577696 - Protein BofC gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02787 BSBS38_02788 BSBS38_02788 BSBS38_02788 2577744 2579051 - Alpha-ketoglutarate permease Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. CsbX subfamily gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02788 BSBS38_02789 BSBS38_02789 iolG iolG 2579122 2580147 - Inositol 2-dehydrogenase Belongs to the Gfo/Idh/MocA family%3B KEGG: bsu:BSU27770 myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02789 BSBS38_02790 BSBS38_02790 BSBS38_02790 2580385 2581032 + Putative serine/threonine-protein kinase YrzF Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bcz:BCZK2452 null%3B Phosphotransferases with an alcohol group as acceptor gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02790 BSBS38_02791 BSBS38_02791 BSBS38_02791 2581078 2581200 - hypothetical protein gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02791 BSBS38_02792 BSBS38_02792 BSBS38_02792 2581285 2581731 + uncharacterized protein gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02792 BSBS38_02793 BSBS38_02793 BSBS38_02793 2581738 2581878 + putative membrane protein YrzT gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02793 BSBS38_02794 BSBS38_02794 BSBS38_02794 2582042 2583496 + Putative sodium/proton-dependent alanine carrier protein YrbD Belongs to the sodium:alanine (SAF) symporter family gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02794 BSBS38_02795 BSBS38_02795 glgC glgC 2583537 2584259 - Glucose-1-phosphate adenylyltransferase Belongs to the TACO1 family%3B KEGG: pmf:P9303_05381 glucose-1-phosphate adenylyltransferase gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02795 BSBS38_02796 BSBS38_02796 BSBS38_02796 2584362 2584958 - Sporulation cortex protein CoxA gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02796 BSBS38_02797 BSBS38_02797 BSBS38_02797 2585106 2586269 - Spore coat assembly protein ExsA Required for the normal assembly and anchoring of both the spore coat and the exosporium layers%3B Contains 1 LysM repeat%3B To B. subtilis SafA gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02797 BSBS38_02798 BSBS38_02798 nadA nadA 2586386 2587492 - Quinolinate synthase Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate%3B Belongs to the quinolinate synthase A family. Type 3 subfamily%3B KEGG: bsu:BSU27850 quinolinate synthase gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02798 BSBS38_02799 BSBS38_02799 nadC nadC 2587479 2588348 - Nicotinate-nucleotide diphosphorylase (carboxylating) Involved in the catabolism of quinolinic acid (QA)%3B Belongs to the NadC/ModD family%3B KEGG: bsu:BSU27860 nicotinate-nucleotide pyrophosphorylase (carboxylating) gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02799 BSBS38_02800 BSBS38_02800 nadB nadB 2588302 2589897 - L-aspartate oxidase Catalyzes the oxidation of L-aspartate to iminoaspartate. Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily%3B KEGG: bsu:BSU27870 L-aspartate oxidase gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02800 BSBS38_02801 BSBS38_02801 BSBS38_02801 2590000 2591187 + Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Seems to be required for NAD biosynthesis (PubMed:8444804)%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: ppf:Pput_1517 cysteine desulfurase gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02801 BSBS38_02802 BSBS38_02802 BSBS38_02802 2591147 2591689 + Transcription repressor NadR In the presence of nicotinic acid represses transcription of the nadBCA and nifS-nadR operons. Also binds to DNA upstream of the niaP gene%2C probably regulating it as well. May bind nicotinic acid gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02802 BSBS38_02803 BSBS38_02803 pheA pheA 2591713 2592570 - Chorismate mutase Contains 1 ACT domain%3B Contains 1 prephenate dehydratase domain%3B KEGG: xfa:XF2325 chorismate mutase / prephenate dehydratase gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02803 BSBS38_02804 BSBS38_02804 pheB pheB 2592587 2593030 - Chorismate mutase Belongs to the UPF0735 family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU27910 chorismate mutase gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02804 BSBS38_02805 BSBS38_02805 BSBS38_02805 2593091 2594377 - GTPase Obg An essential GTPase which binds GTP%2C GDP and possibly (p)ppGpp with moderate affinity%2C with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle%2C stress response%2C ribosome biogenesis and in those bacteria that undergo differentiation%2C in morphogenesis control%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02805 BSBS38_02806 BSBS38_02806 BSBS38_02806 2594411 2594989 - Sporulation initiation phosphotransferase KEGG: bsu:BSU27930 stage 0 sporulation protein B (sporulation initiation phosphotransferase)%3B Transferring phosphorus-containing groups gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02806 BSBS38_02807 BSBS38_02807 BSBS38_02807 2595310 2595594 - 50S ribosomal protein L27 Belongs to the ribosomal protein L27P family gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02807 BSBS38_02808 BSBS38_02808 BSBS38_02808 2595607 2595945 - uncharacterized protein To M. genitalium MG233 gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02808 BSBS38_02809 BSBS38_02809 BSBS38_02809 2595948 2596256 - 50S ribosomal protein L21 This protein binds to 23S rRNA in the presence of protein L20%3B Belongs to the ribosomal protein L21P family gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02809 BSBS38_02810 BSBS38_02810 BSBS38_02810 2596403 2597269 - Stage IV sporulation protein FB Implicated in the coupling of mother cell to forespore gene expression. Required for spore formation. Processes the pro- sigma K factor. Belongs to the peptidase M50B family%3B KEGG: bsu:BSU27970 stage IV sporulation protein FB%3B Metalloendopeptidases gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02810 BSBS38_02811 BSBS38_02811 BSBS38_02811 2597262 2598056 - Stage IV sporulation protein FA gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02811 BSBS38_02812 BSBS38_02812 BSBS38_02812 2598206 2599012 - Septum site-determining protein MinD ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity)%3B Belongs to the ParA family. MinD subfamily gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02812 BSBS38_02813 BSBS38_02813 BSBS38_02813 2599014 2599694 - putative septum site-determining protein MinC Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization%3B Belongs to the MinC family gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02813 BSBS38_02814 BSBS38_02814 BSBS38_02814 2599747 2600265 - Rod shape-determining protein MreD Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity)%3B Belongs to the MreD family gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02814 BSBS38_02815 BSBS38_02815 BSBS38_02815 2600262 2601134 - Cell shape-determining protein MreC Involved in formation and maintenance of cell shape. Required for the formation of proper helical filaments of MreB and for cell wall synthesis in the cylindrical part of the cell leading to cell elongation%3B Belongs to the MreC family gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02815 BSBS38_02816 BSBS38_02816 BSBS38_02816 2601165 2602178 - Rod shape-determining protein MreB Involved in formation of the rod shape of the cell%3B Belongs to the FtsA/MreB family gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02816 BSBS38_02817 BSBS38_02817 BSBS38_02817 2602270 2602965 - UPF0758 protein YsxA Belongs to the UPF0758 family gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02817 BSBS38_02818 BSBS38_02818 BSBS38_02818 2603002 2603571 - Septum formation protein Maf Involved in septum formation. Belongs to the maf family gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02818 BSBS38_02819 BSBS38_02819 BSBS38_02819 2603724 2604722 - Stage II sporulation protein Involved in endospore development. Contains 1 SPOR domain gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02819 BSBS38_02820 BSBS38_02820 comC comC 2604856 2605392 - Type 4 prepilin-like protein leader peptide-processing enzyme Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue%3B Belongs to the peptidase A24 family%3B KEGG: bsu:BSU28070 leader peptidase (prepilin peptidase) / N-methyltransferase%3B Prepilin peptidase gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02820 BSBS38_02821 BSBS38_02821 folC folC 2605742 2607034 - Dihydrofolate synthase Conversion of folates to polyglutamate derivatives. It prefers 5%2C10-methylenetetrahydrofolate%2C rather than 10- formyltetrahydrofolate as folate substrate. Belongs to the folylpolyglutamate synthase family%3B KEGG: bsu:BSU28080 dihydrofolate synthase / folylpolyglutamate synthase gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02821 BSBS38_02822 BSBS38_02822 varS varS 2607094 2609736 - Valine--tRNA ligase As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine%2C to avoid such errors%2C it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity). Catalyzes the attachment of valine to tRNA(Val)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily%3B KEGG: bsu:BSU28090 valyl-tRNA synthetase gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02822 BSBS38_02823 BSBS38_02823 BSBS38_02823 2610184 2610375 + putative membrane protein YszA gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02823 BSBS38_02824 BSBS38_02824 BSBS38_02824 2610394 2611428 - uncharacterized protein gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02824 BSBS38_02825 BSBS38_02825 BSBS38_02825 2611452 2613179 - Stage VI sporulation protein D gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02825 BSBS38_02826 BSBS38_02826 BSBS38_02826 2613310 2614602 - Glutamate-1-semialdehyde 2%2C1-aminomutase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bsu:BSU28120 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02826 BSBS38_02827 BSBS38_02827 hemB hemB 2614632 2615606 - Porphobilinogen synthase Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit%2C each at a distinct site%2C and catalyzes their condensation to form porphobilinogen (By similarity)%3B Belongs to the ALAD family%3B KEGG: bsu:BSU28130 porphobilinogen synthase gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02827 BSBS38_02828 BSBS38_02828 BSBS38_02828 2615603 2616391 - Uroporphyrinogen-III synthase Catalyzes cyclization of the linear tetrapyrrole%2C hydroxymethylbilane%2C to the macrocyclic uroporphyrinogen III%3B Belongs to the uroporphyrinogen-III synthase family%3B KEGG: bsu:BSU28140 uroporphyrinogen-III synthase gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02828 BSBS38_02829 BSBS38_02829 hemC hemC 2616381 2617325 - Hydroxymethylbilane synthase Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps%3B Belongs to the HMBS family%3B KEGG: dak:DaAHT2_0535 hydroxymethylbilane synthase gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02829 BSBS38_02830 BSBS38_02830 BSBS38_02830 2617358 2618188 - Protein HemX Required for HemL synthesis. To M. leprae U1620K gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02830 BSBS38_02831 BSBS38_02831 hemA hemA 2618196 2619563 - Glutamyl-tRNA reductase Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)%3B Belongs to the glutamyl-tRNA reductase family%3B KEGG: wbr:WGLp346 glutamyl-tRNA reductase gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02831 BSBS38_02832 BSBS38_02832 BSBS38_02832 2619793 2620290 + putative membrane protein YsxD gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02832 BSBS38_02833 BSBS38_02833 BSBS38_02833 2620312 2620899 - putative GTP-binding protein EngB Necessary for normal cell division and for the maintenance of normal septation%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family%3B Contains 1 EngB-type G (guanine nucleotide-binding) domain gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02833 BSBS38_02834 BSBS38_02834 BSBS38_02834 2620896 2623220 - Endopeptidase La ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner (By similarity). Has been implicated in preventing sigma(G) activity under non-sporulation conditions%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain%3B KEGG: bsu:BSU28200 ATP-dependent Lon protease gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02834 BSBS38_02835 BSBS38_02835 lonB lonB 2623401 2625059 - Lon protease ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner (By similarity)%3B Belongs to the peptidase S16 family%3B KEGG: bsu:BSU28210 Lon-like ATP-dependent protease%3B Serine endopeptidases gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02835 BSBS38_02836 BSBS38_02836 BSBS38_02836 2625213 2626475 - ATP-dependent Clp protease ATP-binding subunit ClpX ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP%3B Belongs to the ClpX chaperone family gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02836 BSBS38_02837 BSBS38_02837 BSBS38_02837 2626747 2628021 - Trigger factor Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase%3B Belongs to the FKBP-type PPIase family. Tig subfamily%3B Contains 1 PPIase FKBP-type domain gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02837 BSBS38_02838 BSBS38_02838 BSBS38_02838 2628249 2629253 - TPR repeat-containing protein YsoA Contains 3 TPR repeats gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02838 BSBS38_02839 BSBS38_02839 leuD leuD 2629372 2629971 - 3-isopropylmalate dehydratase Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the LeuD family. LeuD type 1 subfamily%3B KEGG: bsu:BSU28250 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02839 BSBS38_02840 BSBS38_02840 leuC leuC 2629984 2631402 - 3-isopropylmalate dehydratase Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily%3B KEGG: bsu:BSU28260 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02840 BSBS38_02841 BSBS38_02841 leuB leuB 2631452 2632549 - 3-isopropylmalate dehydrogenase Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily%3B KEGG: xft:PD1397 3-isopropylmalate dehydrogenase gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02841 BSBS38_02842 BSBS38_02842 leuA leuA 2632570 2634126 - 2-isopropylmalate synthase Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)%3B Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily%3B KEGG: dgg:DGI_2503 2-isopropylmalate synthase gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02842 BSBS38_02843 BSBS38_02843 ilvC ilvC 2634113 2635141 - Ketol-acid reductoisomerase (NADP(+)) Belongs to the ketol-acid reductoisomerase family%3B KEGG: bsu:BSU28290 ketol-acid reductoisomerase gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02843 BSBS38_02844 BSBS38_02844 ilvH ilvH 2635165 2635683 - Acetolactate synthase Belongs to the acetolactate synthase small subunit family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU28300 acetolactate synthase I/III small subunit%3B overlaps another CDS with the same product name gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02844 BSBS38_02845 BSBS38_02845 ilvB ilvB 2635680 2637404 - Acetolactate synthase Belongs to the TPP enzyme family%3B KEGG: bsu:BSU28310 acetolactate synthase I/II/III large subunit%3B overlaps another CDS with the same product name gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02845 BSBS38_02846 BSBS38_02846 BSBS38_02846 2638217 2638552 + uncharacterized protein gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02846 BSBS38_02847 BSBS38_02847 yedL yedL 2638784 2639170 + putative N-acetyltransferase YsnE Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU28330 putative acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02847 BSBS38_02848 BSBS38_02848 BSBS38_02848 2639354 2640178 + Stress response protein YsnF gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02848 BSBS38_02849 BSBS38_02849 BSBS38_02849 2640242 2640315 - tRNA-Arg tRNA gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02849 BSBS38_02850 BSBS38_02850 BSBS38_02850 2640446 2640955 - Putative metallophosphoesterase YsnB Belongs to the metallophosphoesterase superfamily. YfcE family gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02850 BSBS38_02851 BSBS38_02851 rdgB rdgB 2640971 2641558 - XTP/dITP diphosphatase Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool%2C thus preventing their incorporation into DNA and avoiding chromosomal lesions%3B Belongs to the HAM1 NTPase family%3B KEGG: bsu:BSU28360 XTP/dITP diphosphohydrolase gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02851 BSBS38_02852 BSBS38_02852 BSBS38_02852 2641580 2642317 - tRNA nucleotidyltransferase Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates%3B Belongs to the RNase PH family%3B KEGG: bsu:BSU28370 ribonuclease PH gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02852 BSBS38_02853 BSBS38_02853 BSBS38_02853 2642428 2643528 - Spore germination protein GerM gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02853 BSBS38_02854 BSBS38_02854 murI murI 2643643 2644458 - Glutamate racemase Provides the (R)-glutamate required for cell wall biosynthesis%3B Belongs to the aspartate/glutamate racemases family%3B KEGG: bsu:BSU28390 glutamate racemase gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02854 BSBS38_02855 BSBS38_02855 mtaP mtaP 2644469 2644909 - S-methyl-5'-thioadenosine phosphorylase Contains 1 HTH marR-type DNA-binding domain%3B KEGG: tmr:Tmar_1098 5'-methylthioadenosine phosphorylase gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02855 BSBS38_02856 BSBS38_02856 BSBS38_02856 2645154 2645378 - Spore germination protein GerE Involved in the regulation of spore formation. Directs the transcription of several genes that encode structural components of the protein coat that encases the mature spore (CotB%2C CotC%2C CotG%2C CotS%2C CotV%2C CotW%2C CotX%2C CotY and CotZ). Controls also the cgeAB and cgeCDE operons. Contains 1 HTH luxR-type DNA-binding domain gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02856 BSBS38_02857 BSBS38_02857 BSBS38_02857 2645494 2645937 - uncharacterized protein KEGG: bsu:BSU28420 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02857 BSBS38_02858 BSBS38_02858 sdhB sdhB 2645998 2646759 - Succinate dehydrogenase (quinone) Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: bsu:BSU28430 succinate dehydrogenase / fumarate reductase%2C iron-sulfur subunit gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02858 BSBS38_02859 BSBS38_02859 sdhA sdhA 2646762 2648522 - Succinate dehydrogenase (quinone) Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily%3B KEGG: bsu:BSU28440 succinate dehydrogenase / fumarate reductase%2C flavoprotein subunit gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02859 BSBS38_02860 BSBS38_02860 BSBS38_02860 2648556 2649164 - Succinate dehydrogenase cytochrome b558 subunit Di-heme cytochrome of the succinate dehydrogenase complex. Belongs to the cytochrome b558 family gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02860 BSBS38_02861 BSBS38_02861 BSBS38_02861 2649457 2649903 + uncharacterized protein gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02861 BSBS38_02862 BSBS38_02862 BSBS38_02862 2649947 2651173 - Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: vsp:VS_2582 aspartate kinase gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02862 BSBS38_02863 BSBS38_02863 BSBS38_02863 2651543 2653315 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision%3B Belongs to the UvrC family%3B Contains 1 GIY-YIG domain%3B Contains 1 UVR domain gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02863 BSBS38_02864 BSBS38_02864 BSBS38_02864 2653451 2653765 - Thioredoxin Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02864 BSBS38_02865 BSBS38_02865 abfA abfA 2654059 2655546 - Non-reducing end alpha-L-arabinofuranosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-L-arabinofuranosyl residues in different hemicellulosic homopolysaccharides (branched and debranched arabinans) and heteropolysaccharides (arabinoxylans). It is able to hydrolyze the alpha-(1->5)- glycosidic linkages of linear alpha-(1->5)-L-arabinan (debranched)%2C sugar beet arabinan (branched) and wheat arabinoxylan. Moreover%2C it displays higher activity towards branched arabinan%2C a molecule comprising a backbone of alpha- (1->5)-linked L-arabinofuranosyl residues decorated with alpha- (1->2)-%2C and alpha-(1->3)-linked L-arabinofuranosyl units%2C than towards debranched arabinan. In addition%2C arabinoxylan%2C which has L-arabinofuranose residues attached to the main chain by alpha- (1->2)-and/or alpha-(1->3)-glycosidic linkages%2C is preferred to linear alpha-(1->5)-L-arabinan%3B Belongs to the glycosyl hydrolase 51 family%3B KEGG: bsu:BSU28510 alpha-N-arabinofuranosidase gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02865 BSBS38_02866 BSBS38_02866 BSBS38_02866 2655627 2655842 + hypothetical protein gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02866 BSBS38_02867 BSBS38_02867 BSBS38_02867 2655764 2656741 - Electron transfer flavoprotein subunit alpha The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF alpha-subunit/FixB family gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02867 BSBS38_02868 BSBS38_02868 BSBS38_02868 2656777 2657550 - Electron transfer flavoprotein subunit beta The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF beta-subunit/FixA family gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02868 BSBS38_02869 BSBS38_02869 fadB fadB 2657565 2658341 - Enoyl-CoA hydratase Involved in the degradation of long-chain fatty acids. Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: bsu:BSU28540 enoyl-CoA hydratase gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02869 BSBS38_02870 BSBS38_02870 BSBS38_02870 2658356 2658940 - Fatty acid metabolism regulator protein Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation%2C including acdA%2C fadA%2C fadB%2C fadE%2C fadF%2C fadG%2C fadH%2C fadM%2C fadN%2C lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02870 BSBS38_02871 BSBS38_02871 BSBS38_02871 2659045 2660727 - Long-chain-fatty-acid--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: care:LT85_4544 long-chain acyl-CoA synthetase gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02871 BSBS38_02872 BSBS38_02872 BSBS38_02872 2660916 2661320 - UPF0719 transmembrane protein YshE Belongs to the UPF0719 family gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02872 BSBS38_02873 BSBS38_02873 BSBS38_02873 2661335 2663692 - Endonuclease MutS2 Belongs to the DNA mismatch repair MutS family. MutS2 subfamily%3B Contains 1 Smr domain gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02873 BSBS38_02874 BSBS38_02874 BSBS38_02874 2663713 2665425 - DNA polymerase/3'-5' exonuclease PolX Strictly DNA-template-directed DNA polymerase%2C preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a single-nucleotide gap%2C allowing further sealing of the resulting nick by a DNA ligase%2C points to a putative role in base excision repair (BER) during the B. subtilis life cycle. Moreover%2C also possesses a 3'-5' exonuclease activity able to edit unpaired 3'-termini in a gapped DNA substrate and likely involved in resecting unannealed 3'-termini during DNA repair. The same PolX molecule could perform the subsequent gap-filling step. Does not display 5'-deoxyribose 5'-phosphate (dRP) lyase activity%2C as predicted by the lack of the lysine and tyrosine residues responsible for the dRP lyase activity in some other PolX members%3B In the N-terminal sectio%3B belongs to the DNA polymerase type-X family%3B In the C-terminal sectio%3B belongs to the PHP family gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02874 BSBS38_02875 BSBS38_02875 BSBS38_02875 2665499 2666032 - putative transmembrane protein YshB gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02875 BSBS38_02876 BSBS38_02876 BSBS38_02876 2666039 2666296 - Cell division protein ZapA Activator of cell division through the inhibition of FtsZ GTPase activity%2C therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division%3B Belongs to the ZapA family. Type 2 subfamily gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02876 BSBS38_02877 BSBS38_02877 rnhC rnhC 2666430 2667368 + Ribonuclease H Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family. RnhC subfamily%3B KEGG: bsu:BSU28620 ribonuclease HIII gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02877 BSBS38_02878 BSBS38_02878 pheT pheT 2667562 2669976 - Phenylalanine--tRNA ligase Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily%3B Contains 1 B5 domain%3B Contains 1 FDX-ACB domain%3B Contains 1 tRNA-binding domain%3B KEGG: bsu:BSU28630 phenylalanyl-tRNA synthetase beta chain gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02878 BSBS38_02879 BSBS38_02879 pheS pheS 2669992 2671026 - Phenylalanine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily%3B KEGG: gsb:GSUB_07760 phenylalanyl-tRNA synthetase alpha chain gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02879 BSBS38_02880 BSBS38_02880 BSBS38_02880 2671381 2672127 - putative tRNA/rRNA methyltransferase YsgA Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02880 BSBS38_02881 BSBS38_02881 BSBS38_02881 2672246 2672461 + Small%2C acid-soluble spore protein Belongs to the SspI family gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02881 BSBS38_02882 BSBS38_02882 BSBS38_02882 2672530 2673636 + uncharacterized protein Belongs to the CdaR family gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02882 BSBS38_02883 BSBS38_02883 BSBS38_02883 2673739 2675151 + (S)-2-hydroxy-acid oxidase Belongs to the FAD-binding oxidoreductase/transferase type 4 family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bsu:BSU28680 glycolate oxidase gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02883 BSBS38_02884 BSBS38_02884 BSBS38_02884 2675148 2676482 + putative glycolate oxidase iron-sulfur subunit Contains 2 4Fe-4S ferredoxin-type domains gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02884 BSBS38_02885 BSBS38_02885 BSBS38_02885 2676521 2676991 - Lactoylglutathione lyase KEGG: bsr:I33_2926 lactoylglutathione lyase gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02885 BSBS38_02886 BSBS38_02886 BSBS38_02886 2676934 2678730 - Carbon starvation protein A like protein Belongs to the CstA family gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02886 BSBS38_02887 BSBS38_02887 BSBS38_02887 2678882 2680384 - Non-reducing end alpha-L-arabinofuranosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in different hemicellulosic homopolysaccharides (branched and debranched arabinans). It acts preferentially on arabinotriose%2C arabinobiose and linear alpha-(1->5)-L-arabinan%2C and is much less effective on branched sugar beet arabinan%3B Belongs to the glycosyl hydrolase 51 family%3B KEGG: bsu:BSU28720 alpha-N-arabinofuranosidase gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02887 BSBS38_02888 BSBS38_02888 BSBS38_02888 2680403 2681248 - L-arabinose transport system permease protein AraQ Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02888 BSBS38_02889 BSBS38_02889 BSBS38_02889 2681249 2682190 - L-arabinose transport system permease protein AraP Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02889 BSBS38_02890 BSBS38_02890 BSBS38_02890 2682226 2683527 - putative arabinose-binding protein Part of the binding-protein-dependent transport system for L-arabinose. Belongs to the bacterial solute-binding protein 1 family gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02890 BSBS38_02891 BSBS38_02891 araM araM 2683558 2684742 - sn-glycerol-1-phosphate dehydrogenase Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species. Prefers NADH over NADPH as coenzyme. Is also able to catalyze the reverse reaction%2C i. e. the NAD(+)-dependent oxidation of G1P but not of G3P. Does not possess glycerol dehydrogenase activity%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bsu:BSU28760 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02891 BSBS38_02892 BSBS38_02892 BSBS38_02892 2684739 2685548 - Sugar phosphatase araL Catalyzes the dephosphorylation of C5 and C6 carbon sugars in vitro (PubMed:21575135%2C PubMed:25848029). Catalyzes the dephosphorylation of 3'-AMP and phosphoserine in vitro (PubMed:25848029)%3B Belongs to the HAD-like hydrolase superfamily gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02892 BSBS38_02893 BSBS38_02893 araD araD 2685535 2686224 - L-ribulose-5-phosphate 4-epimerase Belongs to the aldolase class II family. AraD/FucA subfamily%3B KEGG: eca:ECA1960 L-ribulose-5-phosphate 4-epimerase gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02893 BSBS38_02894 BSBS38_02894 araB araB 2686241 2687923 - Ribulokinase Belongs to the ribulokinase family%3B KEGG: bsu:BSU28790 L-ribulokinase gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02894 BSBS38_02895 BSBS38_02895 araA araA 2687937 2689427 - L-arabinose isomerase Catalyzes the conversion of L-arabinose to L-ribulose%3B Belongs to the arabinose isomerase family%3B KEGG: bsu:BSU28800 L-arabinose isomerase gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02895 BSBS38_02896 BSBS38_02896 BSBS38_02896 2689626 2690486 - Putative transposase InsO for insertion sequence element IS911B Involved in the transposition of the insertion sequence IS911B. Contains 1 integrase catalytic domain gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02896 BSBS38_02897 BSBS38_02897 BSBS38_02897 2690483 2690815 - hypothetical protein gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02897 BSBS38_02898 BSBS38_02898 BSBS38_02898 2690918 2691889 - Arabinan endo-1%2C5-alpha-L-arabinosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1%2C5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan%2C wheat arabinoxylan and p-nitrophenyl-alpha-L- arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bsu:BSU28810 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02898 BSBS38_02899 BSBS38_02899 BSBS38_02899 2692088 2693173 - Cellulase Putative aminopeptidase. Belongs to the peptidase M42 family%3B KEGG: bsu:BSU28820 endoglucanase gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02899 BSBS38_02900 BSBS38_02900 BSBS38_02900 2693357 2693749 + Sigma-w pathway protein YsdB May mediate a negative feedback loop that down-regulates the expression of the sigma-W regulon following the activation of sigma-W in response to conditions of cell envelope stress. Might interact with and inhibit the activity of the protease PrsW%2C or could bind to the anti-sigma-W factor RsiW and thereby protect it from PrsW-mediated cleavage gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02900 BSBS38_02901 BSBS38_02901 BSBS38_02901 2693765 2694034 - uncharacterized protein gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02901 BSBS38_02902 BSBS38_02902 BSBS38_02902 2694091 2694450 - 50S ribosomal protein L20%2C chloroplastic Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit%3B Belongs to the ribosomal protein L20P family gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02902 BSBS38_02903 BSBS38_02903 BSBS38_02903 2694482 2694682 - 50S ribosomal protein L35 Belongs to the ribosomal protein L35P family gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02903 BSBS38_02904 BSBS38_02904 BSBS38_02904 2694695 2695198 - Translation initiation factor IF-3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits%2C thus enhancing the availability of 30S subunits on which protein synthesis initiation begins%3B Belongs to the IF-3 family gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02904 BSBS38_02905 BSBS38_02905 BSBS38_02905 2695662 2696324 + uncharacterized protein gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02905 BSBS38_02906 BSBS38_02906 BSBS38_02906 2696356 2697051 - Antiholin-like protein LrgB Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgA%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidB/LrgB family. LrgB subfamily gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02906 BSBS38_02907 BSBS38_02907 BSBS38_02907 2697073 2697513 - Antiholin-like protein LrgA Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgB%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidA/LrgA family. LrgA subfamily gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02907 BSBS38_02908 BSBS38_02908 BSBS38_02908 2697647 2698372 - Chemotaxis response regulator protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02908 BSBS38_02909 BSBS38_02909 lytS lytS 2698350 2700131 - Histidine kinase Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism%3B Contains 1 GAF domain%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU28930 two-component system%2C LytT family%2C sensor histidine kinase LytS gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02909 BSBS38_02910 BSBS38_02910 BSBS38_02910 2700298 2701080 + Putative uncharacterized hydrolase YsaA Belongs to the HAD-like hydrolase superfamily gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02910 BSBS38_02911 BSBS38_02911 tarS tarS 2701120 2703051 - Threonine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pami:JCM7686_2413 threonyl-tRNA synthetase gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02911 BSBS38_02912 BSBS38_02912 BSBS38_02912 2703255 2703485 + hypothetical protein gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02912 BSBS38_02913 BSBS38_02913 BSBS38_02913 2703445 2704290 - uncharacterized protein gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02913 BSBS38_02914 BSBS38_02914 BSBS38_02914 2704368 2705009 - TVP38/TMEM64 family membrane protein YtxB Belongs to the TVP38/TMEM64 family gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02914 BSBS38_02915 BSBS38_02915 BSBS38_02915 2705043 2705978 - Primosomal protein DnaI gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02915 BSBS38_02916 BSBS38_02916 BSBS38_02916 2706006 2707424 - Replication initiation and membrane attachment protein gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02916 BSBS38_02917 BSBS38_02917 BSBS38_02917 2707539 2707997 - Transcriptional repressor NrdR Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes%3B Belongs to the NrdR family%3B Contains 1 ATP-cone domain gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02917 BSBS38_02918 BSBS38_02918 speD speD 2708271 2708651 - Adenosylmethionine decarboxylase Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)%2C the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine%3B Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily%3B KEGG: nis:NIS_1526 S-adenosylmethionine decarboxylase gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02918 BSBS38_02919 BSBS38_02919 gapA gapA 2708890 2709912 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02919 BSBS38_02920 BSBS38_02920 BSBS38_02920 2710118 2710498 - putative HTH-type transcriptional regulator YtcD Contains 1 HTH hxlR-type DNA-binding domain gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02920 BSBS38_02921 BSBS38_02921 BSBS38_02921 2710682 2711872 + putative MFS-type transporter YtbD Belongs to the major facilitator superfamily gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02921 BSBS38_02922 BSBS38_02922 dkgA dkgA 2711896 2712738 + 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Belongs to the aldo/keto reductase family%3B KEGG: ece:Z0374 2%2C5-diketo-D-gluconate reductase A gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02922 BSBS38_02923 BSBS38_02923 coaE coaE 2712778 2713371 - Dephospho-CoA kinase Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B Belongs to the CoaE family%3B Contains 1 DPCK (dephospho-CoA kinase) domain%3B KEGG: ppr:PBPRA3204 dephospho-CoA kinase gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02923 BSBS38_02924 BSBS38_02924 BSBS38_02924 2713387 2714019 - Putative membrane protein YtaF gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02924 BSBS38_02925 BSBS38_02925 mutM mutM 2714186 2715022 - DNA-formamidopyrimidine glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines%2C such as 7%2C8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates%3B Belongs to the FPG family%3B Contains 1 FPG-type zinc finger%3B KEGG: bsl:A7A1_0773 formamidopyrimidine-DNA glycosylase gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02925 BSBS38_02926 BSBS38_02926 BSBS38_02926 2715039 2717681 - DNA-directed DNA polymerase In addition to polymerase activity%2C this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity%3B Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B Contains 1 5'-3' exonuclease domain%3B KEGG: bsu:BSU29090 DNA polymerase I gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02926 BSBS38_02927 BSBS38_02927 phoR phoR 2717925 2719664 - Histidine kinase Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU29100 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02927 BSBS38_02928 BSBS38_02928 BSBS38_02928 2719657 2720379 - Phosphate regulon transcriptional regulatory protein This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02928 BSBS38_02929 BSBS38_02929 BSBS38_02929 2720591 2721529 - Malate dehydrogenase Catalyzes the reversible oxidation of malate to oxaloacetate%3B Belongs to the LDH/MDH superfamily. MDH type 3 family%3B KEGG: bsu:BSU29120 malate dehydrogenase gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02929 BSBS38_02930 BSBS38_02930 idh1 idh1 2721573 2722844 - Isocitrate dehydrogenase (NADP(+)) Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: pca:Pcar_1038 isocitrate dehydrogenase gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02930 BSBS38_02931 BSBS38_02931 BSBS38_02931 2723009 2724127 - Citrate (Si)-synthase Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. Belongs to the citrate synthase family%3B KEGG: bsu:BSU29140 citrate synthase gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02931 BSBS38_02932 BSBS38_02932 BSBS38_02932 2724462 2724926 - UPF0756 membrane protein Belongs to the UPF0756 family gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02932 BSBS38_02933 BSBS38_02933 BSBS38_02933 2725022 2726137 + UPF0118 membrane protein YtvI Belongs to the UPF0118 (PerM) family gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02933 BSBS38_02934 BSBS38_02934 BSBS38_02934 2726171 2726554 - UPF0716 protein YtzA Belongs to the UPF0716 (FxsA) family gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02934 BSBS38_02935 BSBS38_02935 BSBS38_02935 2726647 2728404 - Pyruvate kinase Belongs to the pyruvate kinase family%3B KEGG: eco:b1676 pyruvate kinase gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02935 BSBS38_02936 BSBS38_02936 pfkA pfkA 2728447 2729406 - 6-phosphofructokinase Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1%2C6-bisphosphate by ATP%2C the first committing step of glycolysis%3B Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily%3B KEGG: eco:b3916 6-phosphofructokinase 1 gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02936 BSBS38_02937 BSBS38_02937 accA accA 2729590 2730567 - Acetyl-CoA carboxylase Component of the acetyl coenzyme A carboxylase (ACC) complex. First%2C biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA%3B Belongs to the AccA family%3B KEGG: bsu:BSU29200 acetyl-CoA carboxylase carboxyl transferase subunit alpha%3B overlaps another CDS with the same product name gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02937 BSBS38_02938 BSBS38_02938 accD accD 2730552 2731424 - Acetyl-CoA carboxylase Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA%3B Belongs to the AccD/PCCB family%3B KEGG: bsu:BSU29210 acetyl-CoA carboxylase carboxyl transferase subunit beta%3B overlaps another CDS with the same product name gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02938 BSBS38_02939 BSBS38_02939 BSBS38_02939 2731759 2732991 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bsu:BSU29220 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02939 BSBS38_02940 BSBS38_02940 dnaE dnaE 2733128 2736475 - DNA-directed DNA polymerase DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)%3B Belongs to the DNA polymerase type-C family. DnaE subfamily%3B KEGG: bsu:BSU29230 DNA polymerase III subunit alpha gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02940 BSBS38_02941 BSBS38_02941 BSBS38_02941 2736615 2736956 + Sporulation membrane protein YtrH Involved in sporulation. May contribute to cortex formation or stability gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02941 BSBS38_02942 BSBS38_02942 BSBS38_02942 2736953 2737456 + Sporulation membrane protein YtrI Involved in sporulation gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02942 BSBS38_02943 BSBS38_02943 BSBS38_02943 2737558 2737749 + uncharacterized protein gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02943 BSBS38_02944 BSBS38_02944 BSBS38_02944 2737767 2738708 - Bifunctional oligoribonuclease and PAP phosphatase NrnA Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter%2C with a preference for 3-mers. Directionality is controversia%3B shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819)%2C and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP%3B Belongs to the NrnA oligoribonuclease family gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02944 BSBS38_02945 BSBS38_02945 BSBS38_02945 2738839 2739141 + putative membrane protein YtpI gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02945 BSBS38_02946 BSBS38_02946 BSBS38_02946 2739160 2740479 - IMP dehydrogenase Contains 2 CBS domains%3B KEGG: afu:AF_1259 IMP dehydrogenase gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02946 BSBS38_02947 BSBS38_02947 BSBS38_02947 2740590 2741273 - UPF0173 metal-dependent hydrolase Belongs to the UPF0173 family gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02947 BSBS38_02948 BSBS38_02948 BSBS38_02948 2741336 2742103 - 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU29420 3-oxoacyl-(acyl-carrier protein) reductase gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02948 BSBS38_02949 BSBS38_02949 BSBS38_02949 2742230 2742361 - uncharacterized protein gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02949 BSBS38_02950 BSBS38_02950 argH argH 2742426 2743811 - Argininosuccinate lyase Belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B KEGG: bam:Bamb_6457 argininosuccinate lyase gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02950 BSBS38_02951 BSBS38_02951 argG argG 2743808 2745019 - Argininosuccinate synthase Belongs to the argininosuccinate synthase family. Type 1 subfamily%3B KEGG: bsu:BSU29450 argininosuccinate synthase gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02951 BSBS38_02952 BSBS38_02952 BSBS38_02952 2745189 2745701 - Molybdenum cofactor biosynthesis protein May be involved in the biosynthesis of molybdopterin%3B Belongs to the MoaB/Mog family gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02952 BSBS38_02953 BSBS38_02953 ackA ackA 2745786 2747087 - Acetate kinase Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction%3B Belongs to the acetokinase family%3B KEGG: bsx:C663_2794 acetate kinase gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02953 BSBS38_02954 BSBS38_02954 BSBS38_02954 2747321 2748310 - Site-specific DNA-methyltransferase (adenine-specific) To type I restriction system adenine methylases%3B KEGG: bsu:BSU29480 site-specific DNA-methyltransferase (adenine-specific) gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02954 BSBS38_02955 BSBS38_02955 BSBS38_02955 2748371 2748874 - Peroxiredoxin Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)%3B Belongs to the AhpC/TSA family. Tpx subfamily%3B Contains 1 thioredoxin domain%3B KEGG: fau:Fraau_0390 thiol peroxidase%2C atypical 2-Cys peroxiredoxin gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02955 BSBS38_02956 BSBS38_02956 BSBS38_02956 2748982 2749437 - putative spore protein YtfJ gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02956 BSBS38_02957 BSBS38_02957 BSBS38_02957 2749451 2750155 - uncharacterized protein gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02957 BSBS38_02958 BSBS38_02958 BSBS38_02958 2750206 2750700 - putative membrane protein YteJ Contains 1 RDD domain gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02958 BSBS38_02959 BSBS38_02959 sppA sppA 2750713 2751720 - Putative signal peptide peptidase SppA Digestion of cleaved signal peptides (By similarity). Required for efficient processing of precursors under conditions of hyper-secretion. Has a preference for leucine-rich substrate peptides%3B Belongs to the peptidase S49 family%3B KEGG: bsu:BSU29530 protease IV%3B Serine endopeptidases gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02959 BSBS38_02960 BSBS38_02960 BSBS38_02960 2751906 2752709 + NAD(+) kinase Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bsu:BSU29540 NAD+ kinase gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02960 BSBS38_02961 BSBS38_02961 BSBS38_02961 2752741 2754330 - Putative amidohydrolase YtcJ gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02961 BSBS38_02962 BSBS38_02962 acsS acsS 2754350 2755939 - Acetate--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29560 acetyl-CoA synthetase gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02962 BSBS38_02963 BSBS38_02963 BSBS38_02963 2756118 2756327 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02963 BSBS38_02964 BSBS38_02964 BSBS38_02964 2756421 2757626 - putative tRNA sulfurtransferase Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs%2C which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS%2C forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole%2C in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS%3B Belongs to the ThiI family%3B Contains 1 THUMP domain gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02964 BSBS38_02965 BSBS38_02965 BSBS38_02965 2757630 2758775 - Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: bsu:BSU29590 cysteine desulfurase gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02965 BSBS38_02966 BSBS38_02966 BSBS38_02966 2758970 2760307 + Branched-chain amino acid transport system carrier protein BraB Component of the transport system for branched-chain amino acids (leucine%2C isoleucine and valine) Which is coupled to a proton motive force%3B Belongs to the branched chain amino acid transporter family gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02966 BSBS38_02967 BSBS38_02967 BSBS38_02967 2760403 2762091 - Septation ring formation regulator EzrA Negative regulator of FtsZ ring formatio%3B modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization%3B Belongs to the EzrA family gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02967 BSBS38_02968 BSBS38_02968 BSBS38_02968 2762288 2763094 + Histidinol-phosphatase Belongs to the PHP hydrolase family. HisK subfamily%3B KEGG: bsu:BSU29620 histidinol-phosphatase (PHP family) gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02968 BSBS38_02969 BSBS38_02969 BSBS38_02969 2763091 2763714 - putative HTH-type transcriptional regulator YttP Contains 1 HTH tetR-type DNA-binding domain gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02969 BSBS38_02970 BSBS38_02970 BSBS38_02970 2763841 2764332 + Protein YtsP Belongs to the free Met sulfoxide reductase family gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02970 BSBS38_02971 BSBS38_02971 BSBS38_02971 2764370 2766109 - Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: eat:EAT1b_1468 diguanylate cyclase gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02971 BSBS38_02972 BSBS38_02972 BSBS38_02972 2766404 2767006 + 30S ribosomal protein S4 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit%3B With S5 and S12 plays an important role in translational accuracy%3B Belongs to the ribosomal protein S4P family%3B Contains 1 S4 RNA-binding domain gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02972 BSBS38_02973 BSBS38_02973 BSBS38_02973 2767028 2767156 - hypothetical protein gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02973 BSBS38_02974 BSBS38_02974 yarS yarS 2767286 2768554 - Tyrosine--tRNA ligase Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: wbr:WGLp338 tyrosyl-tRNA synthetase gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02974 BSBS38_02975 BSBS38_02975 BSBS38_02975 2768896 2770614 - Acetate--CoA ligase Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29680 acetyl-CoA synthetase gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02975 BSBS38_02976 BSBS38_02976 acuA acuA 2770775 2771407 + Acetoin utilization protein AcuA Part of the acuABC operon%2C which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU29690 acetoin utilization protein AcuA%3B Transferring groups other than amino-acyl groups gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02976 BSBS38_02977 BSBS38_02977 BSBS38_02977 2771434 2772078 + Acetoin utilization protein AcuB Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Contains 2 CBS domains gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02977 BSBS38_02978 BSBS38_02978 BSBS38_02978 2772048 2773238 + Acetoin utilization protein AcuC Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Belongs to the histone deacetylase family gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02978 BSBS38_02979 BSBS38_02979 BSBS38_02979 2773249 2773977 - uncharacterized protein May be involved in some transport function. Belongs to the MotB family%3B Contains 1 OmpA-like domain%3B overlaps another CDS with the same product name gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02979 BSBS38_02980 BSBS38_02980 BSBS38_02980 2773967 2774785 - uncharacterized protein May be involved in some transport function. Belongs to the MotA family%3B overlaps another CDS with the same product name gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02980 BSBS38_02981 BSBS38_02981 BSBS38_02981 2774848 2775852 - Catabolite control protein Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions. Interacts with either P-Ser-HPr or P-Ser-Crh%2C leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre). Binding to DNA allows activation or repression of many different genes and operons%3B Contains 1 HTH lacI-type DNA-binding domain gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02981 BSBS38_02982 BSBS38_02982 aroG aroG 2776128 2777204 - 3-deoxy-7-phosphoheptulonate synthase Belongs to the class-I DAHP synthase family%3B Contains 1 chorismate mutase domain%3B KEGG: bsu:BSU29750 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02982 BSBS38_02983 BSBS38_02983 BSBS38_02983 2777441 2777767 - uncharacterized protein gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02983 BSBS38_02984 BSBS38_02984 BSBS38_02984 2777791 2778246 - uncharacterized protein To C. plantagineum desiccation-related protein clone PCC3-06 gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02984 BSBS38_02985 BSBS38_02985 BSBS38_02985 2778277 2778699 - UPF0478 protein YtxG Belongs to the UPF0478 family gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02985 BSBS38_02986 BSBS38_02986 murC murC 2778861 2780159 - UDP-N-acetylmuramate--L-alanine ligase Cell wall formation%3B Belongs to the MurCDEF family%3B KEGG: bsu:BSU29790 UDP-N-acetylmuramate--alanine ligase gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02986 BSBS38_02987 BSBS38_02987 BSBS38_02987 2780409 2783267 - DNA translocase SftA Required for the accurate completion of chromosome partitioning%2C in part by promoting efficient resolution of chromosome dimers%2C before the formation of the division septum. Binds to DNA in a non-specific manner. Shows ATPase activity. Not required for cytokinesis%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02987 BSBS38_02988 BSBS38_02988 BSBS38_02988 2783427 2784032 - Putative tRNA-binding protein YtpR Contains 1 tRNA-binding domain gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02988 BSBS38_02989 BSBS38_02989 BSBS38_02989 2784048 2784857 - UPF0354 protein Belongs to the UPF0354 family gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02989 BSBS38_02990 BSBS38_02990 BSBS38_02990 2784872 2785195 - Thioredoxin-like protein YtpP Contains 1 thioredoxin domain gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02990 BSBS38_02991 BSBS38_02991 BSBS38_02991 2785428 2785754 + uncharacterized protein overlaps another CDS with the same product name gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02991 BSBS38_02992 BSBS38_02992 BSBS38_02992 2785715 2785876 + uncharacterized protein overlaps another CDS with the same product name gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02992 BSBS38_02993 BSBS38_02993 BSBS38_02993 2785931 2787004 - Putative aminopeptidase YtoP Belongs to the peptidase M42 family%3B KEGG: eat:EAT1b_0712 aminopeptidase%3B Aminopeptidases gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02993 BSBS38_02994 BSBS38_02994 BSBS38_02994 2787163 2787480 + uncharacterized protein gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02994 BSBS38_02995 BSBS38_02995 BSBS38_02995 2787533 2789233 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bsu:BSU29880 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02995 BSBS38_02996 BSBS38_02996 BSBS38_02996 2789316 2790161 - putative quorum-quenching lactonase YtnP Probable hydrolase that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus. Thus%2C serves as a defensive strategy against competing bacteria. The putative target for YtnP may be a gamma-butyrolactone termed A factor%2C which is the quorum- sensing signaling molecule that positively regulates streptomycin production and development of aerial hyphae in S. griseus%3B Belongs to the metallo-beta-lactamase superfamily gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02996 BSBS38_02997 BSBS38_02997 trmB trmB 2790231 2790872 - tRNA (guanine(46)-N(7))-methyltransferase Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family%3B KEGG: bsu:BSU29900 tRNA (guanine-N7-)-methyltransferase gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02997 BSBS38_02998 BSBS38_02998 BSBS38_02998 2791079 2791357 + uncharacterized protein gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02998 BSBS38_02999 BSBS38_02999 BSBS38_02999 2791358 2792155 - Putative phosphotransferase YtmP Belongs to the aminoglycoside phosphotransferase family gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_02999 BSBS38_03000 BSBS38_03000 BSBS38_03000 2792335 2794491 - Pullulanase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bsu:BSU29930 pullulanase gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03000 BSBS38_03001 BSBS38_03001 cerK cerK 2794517 2795446 - Ceramide kinase May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: ath:AT5G51290 ceramide kinase gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03001 BSBS38_03002 BSBS38_03002 BSBS38_03002 2795495 2796409 - uncharacterized protein gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03002 BSBS38_03003 BSBS38_03003 ligT ligT 2796435 2796986 - RNA 2'%2C3'-cyclic phosphodiesterase Hydrolyzes RNA 2'%2C3'-cyclic phosphodiester to an RNA 2'- phosphomonoester%3B Belongs to the 2H phosphoesterase superfamily. ThpR family%3B KEGG: bsr:I33_3052 2'-5' RNA ligase%3B Forming phosphoric ester bonds gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03003 BSBS38_03004 BSBS38_03004 BSBS38_03004 2797135 2798070 + Cysteine synthase Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bsu:BSU29970 cysteine synthase A gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03004 BSBS38_03005 BSBS38_03005 dapE dapE 2798104 2799495 - Succinyl-diaminopimelate desuccinylase Belongs to the peptidase M20A family%3B KEGG: bsu:BSU29980 succinyl-diaminopimelate desuccinylase gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03005 BSBS38_03006 BSBS38_03006 BSBS38_03006 2799592 2800890 + Guanine/hypoxanthine permease PbuO Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03006 BSBS38_03007 BSBS38_03007 BSBS38_03007 2800931 2802088 - Putative transporter YthQ gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03007 BSBS38_03008 BSBS38_03008 BSBS38_03008 2802085 2802795 - putative ABC transporter ATP-binding protein YthP Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03008 BSBS38_03009 BSBS38_03009 BSBS38_03009 2803085 2803306 + putative HTH-type transcriptional regulator YtzE Contains 1 HTH deoR-type DNA-binding domain gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03009 BSBS38_03010 BSBS38_03010 rsuA rsuA 2803428 2804147 - 16S rRNA pseudouridine(516) synthase Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: mex:Mext_2277 16S rRNA pseudouridine516 synthase gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03010 BSBS38_03011 BSBS38_03011 BSBS38_03011 2804216 2805850 - putative cell division protein YtgP May play a role in cell division%2C although it is not essential for growth%3B Belongs to the polysaccharide synthase family gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03011 BSBS38_03012 BSBS38_03012 BSBS38_03012 2806098 2807315 + uncharacterized protein gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03012 BSBS38_03013 BSBS38_03013 BSBS38_03013 2807504 2809042 + Glycine betaine transporter OpuD High-affinity uptake of glycine betaine. Does not mediate either carnitine or choline uptake%3B Belongs to the BCCT transporter (TC 2. A. 15) family gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03013 BSBS38_03014 BSBS38_03014 BSBS38_03014 2809079 2809261 - Sporulation protein cse60 gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03014 BSBS38_03015 BSBS38_03015 BSBS38_03015 2809329 2809997 - uncharacterized protein gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03015 BSBS38_03016 BSBS38_03016 BSBS38_03016 2810019 2811305 - Putative oxidoreductase YteT May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the Gfo/Idh/MocA family gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03016 BSBS38_03017 BSBS38_03017 BSBS38_03017 2811317 2811739 - Putative lipoprotein YteS May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03017 BSBS38_03018 BSBS38_03018 BSBS38_03018 2811817 2812929 - Unsaturated rhamnogalacturonyl hydrolase Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D- galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D- glucuronic acid at the non-reducing terminus%2C although the active pockets of YesR and UGL are very similar%3B Belongs to the glycosyl hydrolase 105 family%3B KEGG: bsu:BSU30120 unsaturated rhamnogalacturonyl hydrolase gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03018 BSBS38_03019 BSBS38_03019 BSBS38_03019 2812946 2813911 - putative multiple-sugar transport system permease YteP Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane. May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03019 BSBS38_03020 BSBS38_03020 BSBS38_03020 2814139 2816445 + putative HTH-type transcriptional regulator YtdP Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03020 BSBS38_03021 BSBS38_03021 BSBS38_03021 2816486 2817982 - Putative ABC transporter peptide-binding protein YtcQ Probably part of a binding-protein-dependent transport system%3B Belongs to the bacterial solute-binding protein 1 family gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03021 BSBS38_03022 BSBS38_03022 BSBS38_03022 2818007 2818888 - putative ABC transporter permease protein YtcP Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03022 BSBS38_03023 BSBS38_03023 BSBS38_03023 2819074 2819835 - uncharacterized protein Belongs to the NAD(P)-dependent epimerase/dehydratase family gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03023 BSBS38_03024 BSBS38_03024 bioI bioI 2819912 2821099 - Pimeloyl-[acyl-carrier protein] synthase Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid%3B Belongs to the cytochrome P450 family%3B KEGG: bsu:BSU30190 pimeloyl-(acyl-carrier protein) synthase gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03024 BSBS38_03025 BSBS38_03025 bioB bioB 2821168 2822175 - Biotin synthase Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism%3B Belongs to the radical SAM superfamily. Biotin synthase family%3B KEGG: bsu:BSU30200 biotin synthase gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03025 BSBS38_03026 BSBS38_03026 bioD bioD 2822178 2822873 - Dethiobiotin synthase Catalyzes a mechanistically unusual reaction%2C the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7%2C8-diaminopelargonic acid (DAPA) to form an ureido ring%3B Belongs to the dethiobiotin synthetase family%3B KEGG: acu:Atc_2625 dethiobiotin synthetase gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03026 BSBS38_03027 BSBS38_03027 bioF bioF 2822870 2824039 - 8-amino-7-oxononanoate synthase Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: mah:MEALZ_2320 8-amino-7-oxononanoate synthase gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03027 BSBS38_03028 BSBS38_03028 bioA bioA 2824029 2825375 - Lysine--8-amino-7-oxononanoate transaminase Catalyzes the transfer of the alpha-amino group from L- lysine to 7-keto-8-aminopelargonic acid (KAPA) to form 7%2C8- diaminopelargonic acid (DAPA). B. subtilis is the only bacterium known to utilize L-lysine as an amino donor in the biosynthesis of DAPA%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily%3B KEGG: bsu:BSU30230 lysine---8-amino-7-oxononanoate aminotransferase gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03028 BSBS38_03029 BSBS38_03029 bioW bioW 2825365 2826099 - 6-carboxyhexanoate--CoA ligase Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP%3B Belongs to the BioW family%3B KEGG: bsu:BSU30240 6-carboxyhexanoate--CoA ligase gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03029 BSBS38_03030 BSBS38_03030 BSBS38_03030 2826351 2827250 - Putative hydrolase Belongs to the dienelactone hydrolase family gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03030 BSBS38_03031 BSBS38_03031 BSBS38_03031 2827468 2828502 + putative HTH-type transcriptional regulator MsmR Contains 1 HTH lacI-type DNA-binding domain gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03031 BSBS38_03032 BSBS38_03032 BSBS38_03032 2828536 2829816 + Putative binding protein MsmE Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 1 family gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03032 BSBS38_03033 BSBS38_03033 BSBS38_03033 2829809 2830321 + Putative ABC transporter permease protein AmyD Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03033 BSBS38_03034 BSBS38_03034 BSBS38_03034 2830318 2830719 + Putative ABC transporter permease protein AmyD Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03034 BSBS38_03035 BSBS38_03035 BSBS38_03035 2830716 2831546 + Putative ABC transporter permease protein AmyC Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03035 BSBS38_03036 BSBS38_03036 BSBS38_03036 2831566 2832864 + Alpha-galactosidase Belongs to the glycosyl hydrolase 4 family%3B KEGG: yin:CH53_2990 alpha-galactosidase gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03036 BSBS38_03037 BSBS38_03037 BSBS38_03037 2832886 2833197 - uncharacterized protein Contains 1 rhodanese domain gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03037 BSBS38_03038 BSBS38_03038 larS larS 2833313 2835727 - Leucine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU30320 leucyl-tRNA synthetase gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03038 BSBS38_03039 BSBS38_03039 BSBS38_03039 2836152 2836490 - uncharacterized protein gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03039 BSBS38_03040 BSBS38_03040 BSBS38_03040 2836890 2837675 + Non-specific serine/threonine protein kinase Exhibits the same spectroscopical features and blue- light induced photochemistry as plants phototropins%2C with the reversible formation of a blue-shifted photoproduct%2C assigned to an FMN-cysteine thiol adduct. Although it is a positive regulator in the activation of the environmental signaling branch of the general stress transcription factor sigma-B%2C its precise role is undetermined%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 STAS domain%3B KEGG: ath:AT3G45780 non-specific serine/threonine protein kinase gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03040 BSBS38_03041 BSBS38_03041 BSBS38_03041 2837912 2839105 - putative MFS-type transporter YttB Belongs to the major facilitator superfamily gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03041 BSBS38_03042 BSBS38_03042 BSBS38_03042 2839294 2840040 + putative membrane protein YttA gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03042 BSBS38_03043 BSBS38_03043 BSBS38_03043 2840077 2842017 - Bacitracin export permease protein BceB Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export. Belongs to the ABC-4 integral membrane protein family gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03043 BSBS38_03044 BSBS38_03044 BSBS38_03044 2842007 2842768 - Bacitracin export ATP-binding protein BceA Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: apl:APL_0626 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03044 BSBS38_03045 BSBS38_03045 bceS bceS 2842870 2843874 - Histidine kinase Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU30390 two-component system%2C OmpR family%2C bacitracin resistance sensor histidine kinase BceS gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03045 BSBS38_03046 BSBS38_03046 BSBS38_03046 2843867 2844562 - Response regulator ArlR Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03046 BSBS38_03047 BSBS38_03047 BSBS38_03047 2844660 2845970 - ABC transporter permease YtrF Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-4 integral membrane protein family gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03047 BSBS38_03048 BSBS38_03048 BSBS38_03048 2845960 2846655 - ABC transporter ATP-binding protein YtrE Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03048 BSBS38_03049 BSBS38_03049 BSBS38_03049 2846670 2847647 - putative ABC transporter permease YtrD Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03049 BSBS38_03050 BSBS38_03050 BSBS38_03050 2847679 2848665 - putative ABC transporter permease YtrC Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03050 BSBS38_03051 BSBS38_03051 BSBS38_03051 2848659 2849537 - L-arabinose transport ATP-binding protein AraG Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03051 BSBS38_03052 BSBS38_03052 BSBS38_03052 2849530 2849922 - HTH-type transcriptional repressor YtrA Negatively regulates ABC transporter complex ytrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03052 BSBS38_03053 BSBS38_03053 BSBS38_03053 2849956 2850093 - hypothetical protein gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03053 BSBS38_03054 BSBS38_03054 BSBS38_03054 2850249 2850521 - uncharacterized protein gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03054 BSBS38_03055 BSBS38_03055 BSBS38_03055 2850683 2851651 + Putative protein YtqA Belongs to the radical SAM superfamily gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03055 BSBS38_03056 BSBS38_03056 BSBS38_03056 2851648 2852232 + Putative rRNA methylase YtqB Belongs to the methyltransferase superfamily gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03056 BSBS38_03057 BSBS38_03057 ytpB ytpB 2852222 2853328 - Tetraprenyl-beta-curcumene synthase Catalyzes the transformation of a linear C35 prenyl diphosphate chain to form tetraprenyl-beta-curcumene%3B KEGG: bsut:BSUB_03240 tetraprenyl-beta-curcumene synthase gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03057 BSBS38_03058 BSBS38_03058 pldB pldB 2853346 2854125 - Lysophospholipase Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis reaction of one acyl bond in phosphatidylcholine in vitro (actual cleavage point is unknown)%2C resulting in lysophosphatidylcholine%3B Belongs to the AB hydrolase superfamily%3B KEGG: bsu:BSU30510 lysophospholipase gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03058 BSBS38_03059 BSBS38_03059 BSBS38_03059 2854174 2854689 + putative transferase YtoA Belongs to the transferase hexapeptide repeat family gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03059 BSBS38_03060 BSBS38_03060 BSBS38_03060 2854935 2856326 - putative amino acid permease YtnA Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03060 BSBS38_03061 BSBS38_03061 BSBS38_03061 2856462 2858360 - Asparagine synthase (glutamine-hydrolyzing) Main asparagine synthetase in vegetative cells. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU30540 asparagine synthase (glutamine-hydrolysing) gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03061 BSBS38_03062 BSBS38_03062 metK metK 2858510 2859712 - Methionine adenosyltransferase Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps%2C AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme%3B Belongs to the AdoMet synthase family%3B KEGG: gbm:Gbem_1725 S-adenosylmethionine synthetase gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03062 BSBS38_03063 BSBS38_03063 pckA pckA 2860215 2861531 + Phosphoenolpyruvate carboxykinase (ATP) Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA%3B Belongs to the phosphoenolpyruvate carboxykinase [ATP] family%3B KEGG: bsu:BSU30560 phosphoenolpyruvate carboxykinase (ATP)%3B overlaps another CDS with the same product name gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03063 BSBS38_03064 BSBS38_03064 BSBS38_03064 2861528 2861797 + Phosphoenolpyruvate carboxykinase (ATP) Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA%3B Belongs to the phosphoenolpyruvate carboxykinase [ATP] family%3B KEGG: ppd:Ppro_3603 phosphoenolpyruvate carboxykinase (ATP)%3B overlaps another CDS with the same product name gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03064 BSBS38_03065 BSBS38_03065 BSBS38_03065 2861836 2862078 - uncharacterized protein gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03065 BSBS38_03066 BSBS38_03066 apeH apeH 2862130 2862903 - Acylaminoacyl-peptidase Belongs to the peptidase S9B family%3B KEGG: ace:Acel_2009 acylaminoacyl-peptidase gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03066 BSBS38_03067 BSBS38_03067 BSBS38_03067 2863030 2864058 + Putative binding protein YtlA Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03067 BSBS38_03068 BSBS38_03068 BSBS38_03068 2864071 2864853 + putative ABC transporter ATP-binding protein YtlC Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03068 BSBS38_03069 BSBS38_03069 BSBS38_03069 2864828 2865640 + putative ABC transporter permease protein YtlD Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03069 BSBS38_03070 BSBS38_03070 BSBS38_03070 2865667 2866143 - 8-oxo-dGTP diphosphatase Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Functions%2C in conjuction with MutT%2C to protect vegetatively growing cells from DNA-damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide). The 2 proteins do not however protect spores. According to PubMed:15576788%2C phosphohydrolase that catalyzes the hydrolysis of all common nucleoside triphosphates as well as of the mutagenic analog 8-oxo- dGTP. The high catalytic efficiency on dGTP is in contrast to results from PubMed:14761999. According to PubMed:14761999%2C catalyzes the hydrolysis of 8-oxo-dGTP with a specific activity 413 times higher than that exhibited against dGTP. Preferentially catalyzes the hydrolysis of 8-oxo-dGTP and 8-oxo-GTP. According to PubMed:15576788%2C hydrolyzes nucleoside triphosphates in a stepwise fashion through the diphosphate to the monophosphate%2C releasing two molecules of inorganic orthophosphate%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU30630 8-oxo-dGTP diphosphatase gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03070 BSBS38_03071 BSBS38_03071 BSBS38_03071 2866353 2866757 - uncharacterized protein Belongs to the Cp-1 holin family gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03071 BSBS38_03072 BSBS38_03072 BSBS38_03072 2866923 2867360 - General stress protein 20U Belongs to the Dps family gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03072 BSBS38_03073 BSBS38_03073 BSBS38_03073 2867489 2867629 + putative membrane protein YtzI gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03073 BSBS38_03074 BSBS38_03074 BSBS38_03074 2867623 2868060 - uncharacterized protein gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03074 BSBS38_03075 BSBS38_03075 luxS luxS 2868180 2868653 - S-ribosylhomocysteine lyase Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4%2C5- dihydroxy-2%2C3-pentadione (DPD)%3B Belongs to the LuxS family%3B KEGG: bsu:BSU30670 S-ribosylhomocysteine lyase gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03075 BSBS38_03076 BSBS38_03076 BSBS38_03076 2869006 2869569 - Carbonate dehydratase Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: salv:SALWKB2_2139 carbonic anhydrase gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03076 BSBS38_03077 BSBS38_03077 BSBS38_03077 2869663 2869911 - 50S ribosomal protein L31 type Belongs to the ribosomal protein L31P family. Type B subfamily gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03077 BSBS38_03078 BSBS38_03078 cydA cydA 2870117 2871448 + Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03078 BSBS38_03079 BSBS38_03079 cydB cydB 2871492 2872532 + Putative cytochrome bd menaquinol oxidase subunit II May have a role in sporulation. Can compensate for the loss of cytochrome aa3%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bsu:BSU30720 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03079 BSBS38_03080 BSBS38_03080 BSBS38_03080 2872586 2872744 + uncharacterized protein gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03080 BSBS38_03081 BSBS38_03081 BSBS38_03081 2872763 2873650 - Manganese transport system membrane protein MntD This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system. Belongs to the ABC-3 integral membrane protein family gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03081 BSBS38_03082 BSBS38_03082 BSBS38_03082 2873640 2874446 - Manganese transport system membrane protein MntC This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system. Belongs to the ABC-3 integral membrane protein family%3B overlaps another CDS with the same product name gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03082 BSBS38_03083 BSBS38_03083 BSBS38_03083 2874443 2874946 - Manganese transport system membrane protein MntC This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system. Belongs to the ABC-3 integral membrane protein family%3B overlaps another CDS with the same product name gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03083 BSBS38_03084 BSBS38_03084 BSBS38_03084 2874952 2875704 - Manganese transport system ATP-binding protein MntB This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03084 BSBS38_03085 BSBS38_03085 BSBS38_03085 2875723 2876643 - Manganese-binding lipoprotein MntA This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system. May be the major manganese uptake system during sporulation. Belongs to the bacterial solute-binding protein 9 family gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03085 BSBS38_03086 BSBS38_03086 menC menC 2876923 2878038 - o-succinylbenzoate synthase Converts 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily%3B KEGG: bsu:BSU30780 O-succinylbenzoate synthase gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03086 BSBS38_03087 BSBS38_03087 menE menE 2878035 2879495 - o-succinylbenzoate--CoA ligase Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl- CoA (OSB-CoA)%3B Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily%3B KEGG: bsu:BSU30790 O-succinylbenzoic acid--CoA ligase gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03087 BSBS38_03088 BSBS38_03088 menB menB 2879586 2880401 - 1%2C4-dihydroxy-2-naphthoyl-CoA synthase Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1%2C4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)%3B Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily%3B KEGG: bsu:BSU30800 naphthoate synthase gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03088 BSBS38_03089 BSBS38_03089 menH menH 2880436 2881260 - 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase Catalyzes a proton abstraction reaction that results in 2%2C5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate (SHCHC)%3B Belongs to the AB hydrolase superfamily. MenH family%3B KEGG: bsu:BSU30810 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03089 BSBS38_03090 BSBS38_03090 menD menD 2881248 2882990 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acidsynthase Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)%3B Belongs to the TPP enzyme family. MenD subfamily%3B KEGG: bsu:BSU30820 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03090 BSBS38_03091 BSBS38_03091 menF menF 2882987 2884402 - Isochorismate synthase Catalyzes the conversion of chorismate to isochorismate%3B Belongs to the isochorismate synthase family%3B KEGG: bsu:BSU30830 menaquinone-specific isochorismate synthase gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03091 BSBS38_03092 BSBS38_03092 BSBS38_03092 2884692 2885411 + uncharacterized protein Contains 1 dksA C4-type zinc finger gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03092 BSBS38_03093 BSBS38_03093 BSBS38_03093 2885420 2886238 - UTP--glucose-1-phosphate uridylyltransferase Belongs to the UDPGP type 2 family%3B KEGG: plu:plu2501 UTP--glucose-1-phosphate uridylyltransferase gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03093 BSBS38_03094 BSBS38_03094 ugdH ugdH 2886410 2887696 + UDP-glucose 6-dehydrogenase Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: pae:PA2022 UDPglucose 6-dehydrogenase gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03094 BSBS38_03095 BSBS38_03095 galE galE 2887693 2888643 + UDP-glucose 4-epimerase Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: fgu:SD28_06695 UDP-glucose 4-epimerase gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03095 BSBS38_03096 BSBS38_03096 BSBS38_03096 2888646 2889869 + Putative glycosyltransferase YtcC Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: gka:GK0838 null%3B Hexosyltransferases gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03096 BSBS38_03097 BSBS38_03097 BSBS38_03097 2889943 2890374 - uncharacterized protein gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03097 BSBS38_03098 BSBS38_03098 BSBS38_03098 2890376 2891431 - Spore coat protein Seems to be required for the assembly of the CotSA protein in spores. Belongs to the CotS family gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03098 BSBS38_03099 BSBS38_03099 BSBS38_03099 2891446 2892579 - Spore coat protein Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03099 BSBS38_03100 BSBS38_03100 BSBS38_03100 2892781 2893842 + Spore coat protein Belongs to the CotS family gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03100 BSBS38_03101 BSBS38_03101 BSBS38_03101 2893922 2894389 + putative membrane protein YtaB Belongs to the TspO/BZRP family gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03101 BSBS38_03102 BSBS38_03102 glgP glgP 2894420 2896816 - Glycogen phosphorylase Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However%2C all known phosphorylases share catalytic and structural properties. Belongs to the glycogen phosphorylase family%3B KEGG: bsu:BSU30940 starch phosphorylase gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03102 BSBS38_03103 BSBS38_03103 glgA glgA 2896803 2898257 - Starch synthase Synthesizes alpha-1%2C4-glucan chains using ADP-glucose%3B Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily%3B KEGG: pat:Patl_0080 starch synthase gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03103 BSBS38_03104 BSBS38_03104 BSBS38_03104 2898254 2899285 - Glucose-1-phosphate adenylyltransferase Required for the synthesis of glycogen. Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family%3B KEGG: bsu:BSU30960 glucose-1-phosphate adenylyltransferase gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03104 BSBS38_03105 BSBS38_03105 BSBS38_03105 2899309 2900451 - Glucose-1-phosphate adenylyltransferase Catalyzes the synthesis of ADP-glucose%2C a sugar donor used in elongation reactions on alpha-glucans%3B Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family%3B KEGG: bsu:BSU30970 glucose-1-phosphate adenylyltransferase gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03105 BSBS38_03106 BSBS38_03106 glgB glgB 2900448 2902331 - 1%2C4-alpha-glucan branching enzyme Catalyzes the formation of the alpha-1%2C6-glucosidic linkages in glycogen by scission of a 1%2C4-alpha-linked oligosaccharide from growing alpha-1%2C4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1%2C6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily%3B KEGG: bsu:BSU30980 1%2C4-alpha-glucan branching enzyme gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03106 BSBS38_03107 BSBS38_03107 BSBS38_03107 2902564 2902635 - tRNA-Glu tRNA gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03107 BSBS38_03108 BSBS38_03108 BSBS38_03108 2902661 2902751 - tRNA-Ser tRNA gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03108 BSBS38_03109 BSBS38_03109 BSBS38_03109 2902755 2902829 - tRNA-Asn tRNA gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03109 BSBS38_03110 BSBS38_03110 BSBS38_03110 2902842 2902918 - tRNA-Ile tRNA gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03110 BSBS38_03111 BSBS38_03111 BSBS38_03111 2902934 2903007 - tRNA-Gly tRNA gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03111 BSBS38_03112 BSBS38_03112 BSBS38_03112 2903018 2903093 - tRNA-His tRNA gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03112 BSBS38_03113 BSBS38_03113 BSBS38_03113 2903119 2903194 - tRNA-Phe tRNA gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03113 BSBS38_03114 BSBS38_03114 BSBS38_03114 2903207 2903283 - tRNA-Asp tRNA gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03114 BSBS38_03115 BSBS38_03115 BSBS38_03115 2903295 2903371 - tRNA-Met tRNA gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03115 BSBS38_03116 BSBS38_03116 BSBS38_03116 2903389 2903481 - tRNA-Ser tRNA gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03116 BSBS38_03117 BSBS38_03117 BSBS38_03117 2903488 2903564 - tRNA-Met tRNA gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03117 BSBS38_03118 BSBS38_03118 BSBS38_03118 2903567 2903643 - tRNA-Met tRNA gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03118 BSBS38_03119 BSBS38_03119 BSBS38_03119 2903663 2903735 - tRNA-Ala tRNA gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03119 BSBS38_03120 BSBS38_03120 BSBS38_03120 2903741 2903817 - tRNA-Pro tRNA gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03120 BSBS38_03121 BSBS38_03121 BSBS38_03121 2903833 2903909 - tRNA-Arg tRNA gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03121 BSBS38_03122 BSBS38_03122 BSBS38_03122 2903919 2904004 - tRNA-Leu tRNA gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03122 BSBS38_03123 BSBS38_03123 BSBS38_03123 2904019 2904093 - tRNA-Gly tRNA gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03123 BSBS38_03124 BSBS38_03124 BSBS38_03124 2904099 2904185 - tRNA-Leu tRNA gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03124 BSBS38_03125 BSBS38_03125 BSBS38_03125 2904196 2904271 - tRNA-Lys tRNA gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03125 BSBS38_03126 BSBS38_03126 BSBS38_03126 2904309 2904384 - tRNA-Thr tRNA gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03126 BSBS38_03127 BSBS38_03127 BSBS38_03127 2904417 2904492 - tRNA-Val tRNA gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03127 BSBS38_03128 BSBS38_03128 BSBS38_03128 2904515 2904630 - 5S ribosomal RNA rRNA gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03128 BSBS38_03129 BSBS38_03129 BSBS38_03129 2904685 2907612 - 23S ribosomal RNA rRNA gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03129 BSBS38_03130 BSBS38_03130 BSBS38_03130 2907783 2909332 - 16S ribosomal RNA rRNA gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03130 BSBS38_03131 BSBS38_03131 BSBS38_03131 2910000 2910578 + Thiamine transporter ThiT Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the ECF family. Thiamine transporter (TC 2. A. 88) subfamily gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03131 BSBS38_03132 BSBS38_03132 BSBS38_03132 2910620 2911141 - putative N-acetyltransferase YuaI Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: tth:TTC0848 null%3B Transferring groups other than amino-acyl groups gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03132 BSBS38_03133 BSBS38_03133 BSBS38_03133 2911159 2912688 - uncharacterized protein To E. coli YqiK and Synechocystis PCC 6803 sll1021 gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03133 BSBS38_03134 BSBS38_03134 BSBS38_03134 2912709 2913233 - putative membrane protein YuaF gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03134 BSBS38_03135 BSBS38_03135 BSBS38_03135 2913401 2913889 + uncharacterized protein gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03135 BSBS38_03136 BSBS38_03136 BSBS38_03136 2913895 2914473 - Putative metal-sulfur cluster biosynthesis protein YuaD Contains 1 MOSC domain gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03136 BSBS38_03137 BSBS38_03137 gbsB gbsB 2914561 2915769 - Alcohol dehydrogenase Essential for the utilization of choline as a precursor%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31050 choline dehydrogenase gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03137 BSBS38_03138 BSBS38_03138 betB betB 2915786 2917258 - Betaine-aldehyde dehydrogenase This is a soluble NAD-dependent betaine aldehyde- specific dehydrogenase. Essential for the utilization of choline as a precursor%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU31060 betaine-aldehyde dehydrogenase gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03138 BSBS38_03139 BSBS38_03139 BSBS38_03139 2917457 2917999 + HTH-type transcriptional repressor GbsR Negatively regulates the expression of the gbsAB and opuB operons. Required to control expression of these genes in response to choline availability. Also required to downregulate glycine betaine production once cellular adjustment to high osmolarity has been achieved%3B Belongs to the GbsR family gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03139 BSBS38_03140 BSBS38_03140 BSBS38_03140 2918196 2918741 + uncharacterized protein Required for complex colony architecture gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03140 BSBS38_03141 BSBS38_03141 BSBS38_03141 2918844 2919176 + hypothetical protein gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03141 BSBS38_03142 BSBS38_03142 BSBS38_03142 2919173 2920033 + Putative transposase InsO for insertion sequence element IS911B Involved in the transposition of the insertion sequence IS911B. Contains 1 integrase catalytic domain gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03142 BSBS38_03143 BSBS38_03143 BSBS38_03143 2920421 2921089 + Ktr system potassium uptake protein Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03143 BSBS38_03144 BSBS38_03144 BSBS38_03144 2921096 2922433 + Ktr system potassium uptake protein Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the TrkH potassium transport family. Ktr (TC 2. A. 38. 4) subfamily gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03144 BSBS38_03145 BSBS38_03145 BSBS38_03145 2922470 2922733 - putative membrane protein YubF gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03145 BSBS38_03146 BSBS38_03146 BSBS38_03146 2922842 2923876 - N-acetylmuramoyl-L-alanine amidase Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: lsa:LSA1558 N-acetylmuramoyl-L-alanine amidase gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03146 BSBS38_03147 BSBS38_03147 BSBS38_03147 2923851 2925386 - putative MFS-type transporter YubD Belongs to the major facilitator superfamily gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03147 BSBS38_03148 BSBS38_03148 cdo1 cdo1 2925905 2926390 + Cysteine dioxygenase Belongs to the cysteine dioxygenase family%3B KEGG: bsu:BSU31140 cysteine dioxygenase gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03148 BSBS38_03149 BSBS38_03149 BSBS38_03149 2926497 2926569 - tRNA-Ala tRNA gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03149 BSBS38_03150 BSBS38_03150 bacA bacA 2926677 2927507 - Undecaprenyl-diphosphate phosphatase Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: bsu:BSU31150 undecaprenyl-diphosphatase gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03150 BSBS38_03151 BSBS38_03151 BSBS38_03151 2927600 2928766 - UPF0118 membrane protein YubA Belongs to the UPF0118 (PerM) family gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03151 BSBS38_03152 BSBS38_03152 BSBS38_03152 2928948 2929934 + putative oxidoreductase YgjR Belongs to the Gfo/Idh/MocA family%3B KEGG: ecc:c3845 null%3B Oxidoreductases gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03152 BSBS38_03153 BSBS38_03153 rhaA rhaA 2930004 2931248 - L-rhamnose isomerase Belongs to the rhamnose isomerase family%3B KEGG: bsu:BSU31180 L-rhamnose isomerase gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03153 BSBS38_03154 BSBS38_03154 rhaM rhaM 2931274 2931588 - L-rhamnose mutarotase Involved in the anomeric conversion of L-rhamnose%3B Belongs to the rhamnose mutarotase family%3B KEGG: eco:b3901 L-rhamnose mutarotase gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03154 BSBS38_03155 BSBS38_03155 rhaB rhaB 2931606 2933063 - Rhamnulokinase Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate%3B Belongs to the rhamnulokinase family%3B KEGG: bsu:BSU31200 rhamnulokinase gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03155 BSBS38_03156 BSBS38_03156 BSBS38_03156 2933068 2933844 - putative HTH-type transcriptional regulator YulB Contains 1 HTH deoR-type DNA-binding domain gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03156 BSBS38_03157 BSBS38_03157 BSBS38_03157 2933902 2935971 - putative oxidoreductase YuxG Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU31220 null%3B Oxidoreductases gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03157 BSBS38_03158 BSBS38_03158 BSBS38_03158 2936107 2937534 - Methyl-accepting chemotaxis protein TlpB Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03158 BSBS38_03159 BSBS38_03159 BSBS38_03159 2937558 2938094 - Methyl-accepting chemotaxis protein TlpB Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03159 BSBS38_03160 BSBS38_03160 BSBS38_03160 2938208 2940193 - Methyl-accepting chemotaxis protein McpA Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03160 BSBS38_03161 BSBS38_03161 BSBS38_03161 2940316 2942223 - Methyl-accepting chemotaxis protein TlpA Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03161 BSBS38_03162 BSBS38_03162 BSBS38_03162 2942400 2944388 - Methyl-accepting chemotaxis protein McpB Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03162 BSBS38_03163 BSBS38_03163 BSBS38_03163 2944547 2945284 + Protein-glutamine gamma-glutamyltransferase Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. In wild-type spores at 37 degrees Celsius%2C tgl mediates the cross- linking of GerQ in higher molecular mass forms%2C probably in cooperation with YabG. Belongs to the bacillus TGase family%3B KEGG: bsu:BSU31270 protein-glutamine gamma-glutamyltransferase gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03163 BSBS38_03164 BSBS38_03164 BSBS38_03164 2945298 2945552 - uncharacterized protein gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03164 BSBS38_03165 BSBS38_03165 ncd2 ncd2 2945810 2946208 - Nitronate monooxygenase Belongs to the UPF0047 family%3B KEGG: bao:BAMF_2926 nitronate monooxygenase gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03165 BSBS38_03166 BSBS38_03166 malZ malZ 2946328 2947992 - Alpha-glucosidase Belongs to the glycosyl hydrolase 13 family%3B KEGG: aza:AZKH_2678 alpha-glucosidase gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03166 BSBS38_03167 BSBS38_03167 BSBS38_03167 2948119 2949408 - UPF0053 protein YugS Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03167 BSBS38_03168 BSBS38_03168 BSBS38_03168 2949452 2950129 - Putative membrane protease YugP gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03168 BSBS38_03169 BSBS38_03169 BSBS38_03169 2950171 2950434 - putative membrane protein YuzI gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03169 BSBS38_03170 BSBS38_03170 BSBS38_03170 2950481 2950813 + Protein mistic Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03170 BSBS38_03171 BSBS38_03171 BSBS38_03171 2950810 2951796 + Putative potassium channel protein YugO Contains 1 RCK N-terminal domain gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03171 BSBS38_03172 BSBS38_03172 BSBS38_03172 2951793 2952197 - uncharacterized protein gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03172 BSBS38_03173 BSBS38_03173 BSBS38_03173 2952257 2952685 - uncharacterized protein gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03173 BSBS38_03174 BSBS38_03174 BSBS38_03174 2952687 2954039 - Glucose-6-phosphate isomerase Belongs to the GPI family%3B KEGG: bsu:BSU31350 glucose-6-phosphate isomerase gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03174 BSBS38_03175 BSBS38_03175 BSBS38_03175 2954151 2955323 - putative NADH-dependent butanol dehydrogenase Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03175 BSBS38_03176 BSBS38_03176 BSBS38_03176 2955425 2956588 - putative NADH-dependent butanol dehydrogenase Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03176 BSBS38_03177 BSBS38_03177 BSBS38_03177 2956818 2957054 + putative membrane protein YuzA gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03177 BSBS38_03178 BSBS38_03178 BSBS38_03178 2957133 2957525 - General stress protein Contains 1 S1 motif domain gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03178 BSBS38_03179 BSBS38_03179 BSBS38_03179 2957726 2958808 - Aromatic-amino-acid aminotransferase Catalyzes the transamination of phenylalanine%2C tyrosine and tryptophan. Shows virtually no activity towards aspartic acid%2C alanine%2C valine or isoleucine%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU31400 aminotransferase%3B Transaminases gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03179 BSBS38_03180 BSBS38_03180 BSBS38_03180 2958887 2959387 - putative HTH-type transcriptional regulator YugG Contains 1 HTH asnC-type DNA-binding domain gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03180 BSBS38_03181 BSBS38_03181 BSBS38_03181 2959535 2960356 + Haloalkane dehalogenase Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: hme:HFX_2390 haloalkane dehalogenase gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03181 BSBS38_03182 BSBS38_03182 BSBS38_03182 2960382 2960642 - uncharacterized protein gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03182 BSBS38_03183 BSBS38_03183 patB patB 2960729 2961892 + Cystathionine beta-lyase Catalyzes the transformation of cystathionine to homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily%3B KEGG: bsu:BSU31440 cystathione beta-lyase gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03183 BSBS38_03184 BSBS38_03184 kinB kinB 2962018 2963304 + Histidine kinase Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the KinB activity. Contains 1 histidine kinase domain%3B KEGG: bsu:BSU31450 two-component system%2C sporulation sensor kinase B gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03184 BSBS38_03185 BSBS38_03185 BSBS38_03185 2963350 2963736 + Kinase-associated lipoprotein gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03185 BSBS38_03186 BSBS38_03186 BSBS38_03186 2963763 2964380 - putative 3'-5' exonuclease KapD Specifically inhibits the KinA pathway to sporulation%3B Contains 1 exonuclease domain gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03186 BSBS38_03187 BSBS38_03187 BSBS38_03187 2964456 2964659 - hypothetical protein gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03187 BSBS38_03188 BSBS38_03188 BSBS38_03188 2964712 2965770 + putative MFS-type transporter YuxJ Belongs to the major facilitator superfamily gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03188 BSBS38_03189 BSBS38_03189 BSBS38_03189 2965863 2967737 + Penicillin-binding protein In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03189 BSBS38_03190 BSBS38_03190 nagA nagA 2967758 2968171 + Alpha-N-acetylgalactosaminidase Belongs to the DCC thiol-disulfide oxidoreductase family%3B KEGG: dfa:DFA_08734 alpha-N-acetylgalactosaminidase gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03190 BSBS38_03191 BSBS38_03191 BSBS38_03191 2968374 2968931 - putative membrane protein YufK gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03191 BSBS38_03192 BSBS38_03192 yufL yufL 2969109 2970710 + Histidine kinase Member of a two-component regulatory system MalK/MalR. Involved in the activation of maeA%2C maeN and yflS in presence of malate. Probably activates MalR by phosphorylation%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU31520 two-component system%2C CitB family%2C sensor histidine kinase MalK gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03192 BSBS38_03193 BSBS38_03193 BSBS38_03193 2970703 2971410 + Transcriptional regulatory protein DcuR Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC%3B nuoA%3B dcu%3B dcu%3B sdhCDA%3B etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA (By similarity)%3B Contains 1 response regulatory domain gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03193 BSBS38_03194 BSBS38_03194 BSBS38_03194 2971835 2972962 + putative lipoprotein YufN Belongs to the BMP lipoprotein family gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03194 BSBS38_03195 BSBS38_03195 BSBS38_03195 2973038 2974570 + Monosaccharide-transporting ATPase Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains%3B KEGG: bsu:BSU31550 simple sugar transport system ATP-binding protein gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03195 BSBS38_03196 BSBS38_03196 BSBS38_03196 2974563 2975609 + putative ABC transporter permease protein YufP Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03196 BSBS38_03197 BSBS38_03197 BSBS38_03197 2975610 2976569 + putative ABC transporter permease protein YufQ Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03197 BSBS38_03198 BSBS38_03198 BSBS38_03198 2976724 2978070 + Na(+)-malate symporter Acts as a Na(+)-malate symporter%2C as it catalyzes malate-dependent uptake of Na(+) and Na(+)-dependent uptake of malate%3B Belongs to the sodium:citrate (SCF) symporter family gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03198 BSBS38_03199 BSBS38_03199 BSBS38_03199 2978106 2978321 - uncharacterized protein gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03199 BSBS38_03200 BSBS38_03200 BSBS38_03200 2978551 2980956 + Na(+)/H(+) antiporter subunit A1 Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit A family gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03200 BSBS38_03201 BSBS38_03201 BSBS38_03201 2980949 2981380 + Na(+)/H(+) antiporter subunit Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit B family gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03201 BSBS38_03202 BSBS38_03202 nuoK nuoK 2981380 2981721 + NADH:ubiquinone reductase (H(+)-translocating) Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit C family%3B KEGG: tcx:Tcr_0062 NADH-quinone oxidoreductase subunit K gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03202 BSBS38_03203 BSBS38_03203 BSBS38_03203 2981705 2983195 + Na(+)/H(+) antiporter subunit D Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit D family gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03203 BSBS38_03204 BSBS38_03204 BSBS38_03204 2983201 2983677 + Na(+)/H(+) antiporter subunit Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential%2C and is thus inferred to be electrogenic. Does not transport K(+)%2C Ca(2+) or Mg(2+). Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit E family%3B overlaps another CDS with the same product name gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03204 BSBS38_03205 BSBS38_03205 BSBS38_03205 2983677 2983961 + Na(+)/H(+) antiporter subunit Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Involved in cholate and Na(+) efflux activities%2C which may be mechanistically coupled. Does not require other Mrp proteins for its own function. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit F family%3B overlaps another CDS with the same product name gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03205 BSBS38_03206 BSBS38_03206 BSBS38_03206 2983945 2984319 + Na(+)/H(+) antiporter subunit May enhance MrpA stability%2C assembly%2C or function. May play chaperone or assembly roles for MrpA and perhaps for other mrp proteins. Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Belongs to the CPA3 antiporters (TC 2. A. 63) subunit G family%3B overlaps another CDS with the same product name gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03206 BSBS38_03207 BSBS38_03207 menI menI 2984358 2984741 - 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase Is not required for competence. Belongs to the thioesterase PaaI family%3B KEGG: sty:STY1757 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03207 BSBS38_03208 BSBS38_03208 BSBS38_03208 2984757 2985401 - Transcriptional regulatory protein ComA Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes%2C including genes of the srfA operon%2C degQ%2C rapA%2C rapC%2C rapE%2C rapF%2C etc. Regulates indirectly%2C through the regulation of comK transcription%2C the expression of late competence genes%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03208 BSBS38_03209 BSBS38_03209 comP comP 2985482 2987794 - Histidine kinase Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation%2C at least partly interchangeable with that of SpoIIJ. Probably activates ComA by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bso:BSNT_04664 two-component system%2C NarL family%2C sensor histidine kinase ComP gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03209 BSBS38_03210 BSBS38_03210 BSBS38_03210 2987810 2988031 - hypothetical protein gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03210 BSBS38_03211 BSBS38_03211 BSBS38_03211 2988033 2988980 - Competence regulatory protein ComQ Involved in the maturation of ComX%2C part of a major quorum-sensing system that regulates the development of genetic competence gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03211 BSBS38_03212 BSBS38_03212 BSBS38_03212 2989081 2989221 - Degradation enzyme regulation protein DegQ Stimulates the phosphotransfer from phospho-DegS to DegU (By similarity). Affects protease and levansucrose production%3B Belongs to the DegQ family gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03212 BSBS38_03213 BSBS38_03213 BSBS38_03213 2989425 2989568 + hypothetical protein gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03213 BSBS38_03214 BSBS38_03214 BSBS38_03214 2989683 2990051 + uncharacterized protein gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03214 BSBS38_03215 BSBS38_03215 BSBS38_03215 2990027 2991256 - uncharacterized protein Contains 1 EAL domain gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03215 BSBS38_03216 BSBS38_03216 pncB pncB 2991392 2992864 - Nicotinate phosphoribosyltransferase Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN)%3B Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP%3B Belongs to the NAPRTase family%3B KEGG: bsu:BSU31750 nicotinate phosphoribosyltransferase gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03216 BSBS38_03217 BSBS38_03217 BSBS38_03217 2992880 2993431 - putative isochorismatase family protein PncA Belongs to the isochorismatase family gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03217 BSBS38_03218 BSBS38_03218 BSBS38_03218 2993528 2993926 - uncharacterized protein gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03218 BSBS38_03219 BSBS38_03219 BSBS38_03219 2993998 2994246 - uncharacterized protein gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03219 BSBS38_03220 BSBS38_03220 BSBS38_03220 2994319 2994540 - Spore germination protein-like protein YueG Belongs to the GerPA/GerPF family gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03220 BSBS38_03221 BSBS38_03221 BSBS38_03221 2994600 2995709 - Phosphoribosylaminoimidazolesuccinocarboxamide synthase Belongs to the UPF0118 (PerM) family%3B KEGG: tbd:Tbd_2668 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03221 BSBS38_03222 BSBS38_03222 BSBS38_03222 2995824 2996213 + uncharacterized protein gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03222 BSBS38_03223 BSBS38_03223 BSBS38_03223 2996254 2996490 - uncharacterized protein gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03223 BSBS38_03224 BSBS38_03224 BSBS38_03224 2996667 2997197 - Putative phosphohydrolase YueE Contains 1 HD domain gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03224 BSBS38_03225 BSBS38_03225 yueD yueD 2997395 2998126 - Benzil reductase ((S)-benzoin forming) Reduces benzil stereospecifically to (S)-benzoin%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bba:Bd0327 benzil reductase ((S)-benzoin forming) gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03225 BSBS38_03226 BSBS38_03226 BSBS38_03226 2998189 2998686 - uncharacterized protein gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03226 BSBS38_03227 BSBS38_03227 BSBS38_03227 2998676 3001855 - Bacteriophage SPP1 adsorption protein YueB Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03227 BSBS38_03228 BSBS38_03228 BSBS38_03228 3001852 3006372 - Ftsk domain-containing protein YukB Contains 2 FtsK domains gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03228 BSBS38_03229 BSBS38_03229 BSBS38_03229 3006336 3007754 - Histidine kinase Belongs to the EssB family%3B KEGG: mef:MSWH1_3188 two-component system%2C chemotaxis family%2C sensor kinase CheA gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03229 BSBS38_03230 BSBS38_03230 BSBS38_03230 3007769 3008008 - putative ubiquitin-like protein YukD gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03230 BSBS38_03231 BSBS38_03231 BSBS38_03231 3008078 3008371 - uncharacterized protein Belongs to the ESAT-6 (esx) family gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03231 BSBS38_03232 BSBS38_03232 BSBS38_03232 3008932 3010161 + Transcriptional activator AdeR Mediates ald expression in response to alanine availability and is important for normal sporulation in B. subtilis%3B Belongs to the CdaR family gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03232 BSBS38_03233 BSBS38_03233 pntA pntA 3010263 3011399 + NAD(P)(+) transhydrogenase (Re/Si-specific) May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer%3B Belongs to the AlaDH/PNT family%3B KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03233 BSBS38_03234 BSBS38_03234 BSBS38_03234 3011511 3012188 + uncharacterized protein gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03234 BSBS38_03235 BSBS38_03235 BSBS38_03235 3012232 3012441 - uncharacterized protein gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03235 BSBS38_03236 BSBS38_03236 BSBS38_03236 3012457 3019593 - Dimodular nonribosomal peptide synthase Specifically adenylates threonine and glycine%2C and loads them onto their corresponding peptidyl carrier domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 2 acyl carrier domains gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03236 BSBS38_03237 BSBS38_03237 BSBS38_03237 3019613 3020551 - Isochorismatase Belongs to the isochorismatase family%3B Contains 1 acyl carrier domain%3B KEGG: bsu:BSU31970 bifunctional isochorismate lyase / aryl carrier protein gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03237 BSBS38_03238 BSBS38_03238 entE entE 3020579 3022198 - (2%2C3-dihydroxybenzoyl)adenylate synthase Activation of the carboxylate group of 2%2C3-dihydroxy- benzoate (DHB)%2C via ATP-dependent PPi exchange reactions%2C to the acyladenylate. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU31980 2%2C3-dihydroxybenzoate-AMP ligase gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03238 BSBS38_03239 BSBS38_03239 entC entC 3022227 3023423 - Isochorismate synthase Belongs to the isochorismate synthase family%3B KEGG: bsu:BSU31990 isochorismate synthase gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03239 BSBS38_03240 BSBS38_03240 entA entA 3023449 3024234 - 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU32000 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03240 BSBS38_03241 BSBS38_03241 BSBS38_03241 3024428 3025309 - Ferri-bacillibactin esterase BesA Catalyzes the hydrolysis of the trilactone cycle of ferri-bacillibactin (ferri-BB) complex%2C leading to the formation of bacillibactin monomers and to cytosolic iron release%2C thus making iron available for metabolic use. Can also hydrolyze bacillibactin (BB)%2C however the catalytic efficiency for ferri-BB hydrolysis is much higher than for BB%3B Belongs to the esterase D family gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03241 BSBS38_03242 BSBS38_03242 yedY yedY 3025511 3026107 - putative oxidoreductase YuiH KEGG: bsu:BSU32020 sulfoxide reductase catalytic subunit YedY%3B Acting on a sulfur group of donors gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03242 BSBS38_03243 BSBS38_03243 BSBS38_03243 3026208 3026810 + Putative biotin transporter BioYB Putative biotin transporter%3B Belongs to the BioY family gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03243 BSBS38_03244 BSBS38_03244 BSBS38_03244 3026880 3028208 - Putative amino acid transporter YuiF gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03244 BSBS38_03245 BSBS38_03245 carP carP 3028355 3029857 - Leucyl aminopeptidase Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)%3B Belongs to the peptidase M17 family%3B KEGG: bsu:BSU32050 leucyl aminopeptidase gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03245 BSBS38_03246 BSBS38_03246 BSBS38_03246 3030015 3030491 + putative membrane protein YuiD gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03246 BSBS38_03247 BSBS38_03247 BSBS38_03247 3030522 3031178 - uncharacterized protein gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03247 BSBS38_03248 BSBS38_03248 BSBS38_03248 3031282 3031602 - putative membrane protein YuiB gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03248 BSBS38_03249 BSBS38_03249 BSBS38_03249 3031972 3033192 - NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32100 NADH dehydrogenase gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03249 BSBS38_03250 BSBS38_03250 BSBS38_03250 3033524 3034522 + Thioredoxin-disulfide reductase Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bsu:BSU32110 thioredoxin reductase (NADPH) gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03250 BSBS38_03251 BSBS38_03251 BSBS38_03251 3034561 3034701 - uncharacterized protein gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03251 BSBS38_03252 BSBS38_03252 guaC guaC 3034978 3035958 + GMP reductase Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase%2C nucleoside and nucleotide derivatives of G to A nucleotides%2C and in maintaining the intracellular balance of A and G nucleotides%3B Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily%3B KEGG: bsu:BSU32130 GMP reductase gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03252 BSBS38_03253 BSBS38_03253 BSBS38_03253 3036032 3036655 - Protease synthase and sporulation protein PAI Involved in the reduction of extracellular and cell- associated protease levels%2C as well as in the reduced levels of alpha-amylase%2C levansucrase%2C alkaline phosphatase and sporulation inhibition%2C when present in high copy number. Belongs to the PaiB family gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03253 BSBS38_03254 BSBS38_03254 BSBS38_03254 3036679 3037185 - Spermidine/spermine N(1)-acetyltransferase Involved in the protection against polyamine toxicity by regulating their concentration. Also could be involved in the negative control of sporulation as well as production of degradative enzymes such as alpha-amylase%2C levansucrase and alkaline phosphatase. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It possesses N1- acetyltransferase activity toward polyamine substrates including spermidine%2C spermine%2C aminopropylcadaverine%2C norspermidine%2C homospermidine%2C N(8)-acetylspermidine%2C diaminopropane and agmatine%3B Contains 1 N-acetyltransferase domain%3B KEGG: gfo:GFO_2080 null%3B Transferring groups other than amino-acyl groups gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03254 BSBS38_03255 BSBS38_03255 BSBS38_03255 3037535 3037897 - Iron-sulfur cluster insertion protein ErpA Required for insertion of 4Fe-4S clusters for at least IspG%3B Belongs to the HesB/IscA family gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03255 BSBS38_03256 BSBS38_03256 dapF dapF 3037976 3038830 - Diaminopimelate epimerase Catalyzes the stereoinversion of LL-2%2C6- diaminoheptanedioate (L%2CL-DAP) to meso-diaminoheptanedioate (meso- DAP)%2C a precursor of L-lysine and an essential component of the bacterial peptidoglycan%3B Belongs to the diaminopimelate epimerase family%3B KEGG: bsu:BSU32170 diaminopimelate epimerase gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03256 BSBS38_03257 BSBS38_03257 BSBS38_03257 3038953 3040167 - putative transporter YutK Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03257 BSBS38_03258 BSBS38_03258 BSBS38_03258 3040303 3040539 - UPF0349 protein Belongs to the UPF0349 family gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03258 BSBS38_03259 BSBS38_03259 BSBS38_03259 3040841 3041869 + NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32200 NADH dehydrogenase gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03259 BSBS38_03260 BSBS38_03260 BSBS38_03260 3041895 3042218 - Putative disulfide oxidoreductase YuzD gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03260 BSBS38_03261 BSBS38_03261 BSBS38_03261 3042420 3042656 + Putative nitrogen fixation protein YutI May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins%3B Belongs to the NifU family gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03261 BSBS38_03262 BSBS38_03262 BSBS38_03262 3042698 3044671 - putative peptidase Belongs to the peptidase S9B family gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03262 BSBS38_03263 BSBS38_03263 BSBS38_03263 3044778 3045707 - Homoserine kinase Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate%3B Belongs to the GHMP kinase family. Homoserine kinase subfamily%3B KEGG: bsu:BSU32240 homoserine kinase gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03263 BSBS38_03264 BSBS38_03264 thrC thrC 3045704 3046771 - Threonine synthase Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine%3B Belongs to the threonine synthase family%3B KEGG: bsl:A7A1_2331 threonine synthase gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03264 BSBS38_03265 BSBS38_03265 BSBS38_03265 3046762 3048063 - Homoserine dehydrogenase Belongs to the homoserine dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: seds:AAY24_06030 homoserine dehydrogenase gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03265 BSBS38_03266 BSBS38_03266 BSBS38_03266 3048264 3049283 - Endospore coat-associated protein YutH Involved in sporulation%3B Belongs to the CotS family gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03266 BSBS38_03267 BSBS38_03267 BSBS38_03267 3049436 3049936 + Phosphatidylglycerophosphatase To B. subtilis YpjQ%3B KEGG: acl:ACL_0288 phosphatidylglycerophosphatase A gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03267 BSBS38_03268 BSBS38_03268 BSBS38_03268 3049963 3050733 - 4-nitrophenylphosphatase Belongs to the HAD-like hydrolase superfamily%3B KEGG: bsu:BSU32290 4-nitrophenyl phosphatase gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03268 BSBS38_03269 BSBS38_03269 BSBS38_03269 3050762 3051196 - UPF0331 protein YutE Belongs to the UPF0331 family gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03269 BSBS38_03270 BSBS38_03270 BSBS38_03270 3051220 3051495 - uncharacterized protein gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03270 BSBS38_03271 BSBS38_03271 BSBS38_03271 3051609 3052241 + putative lipoprotein YutC gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03271 BSBS38_03272 BSBS38_03272 lipA lipA 3052257 3053153 - Lipoyl synthase Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes%2C thereby converting the octanoylated domains into lipoylated derivatives%3B Belongs to the radical SAM superfamily. Lipoyl synthase family%3B KEGG: bsu:BSU32330 lipoic acid synthetase gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03272 BSBS38_03273 BSBS38_03273 BSBS38_03273 3053388 3054368 + L-Ala--D-Glu endopeptidase L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore%2C is required for the endospore cortex maturation%3B Belongs to the peptidase M23B family gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03273 BSBS38_03274 BSBS38_03274 BSBS38_03274 3054396 3055160 - Sporulation protein YunB Required for sporulation gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03274 BSBS38_03275 BSBS38_03275 BSBS38_03275 3055233 3055538 - uncharacterized protein gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03275 BSBS38_03276 BSBS38_03276 BSBS38_03276 3055603 3056991 - 5'-nucleotidase Belongs to the metallophosphoesterase superfamily%3B KEGG: llm:llmg_0192 5'-nucleotidase gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03276 BSBS38_03277 BSBS38_03277 BSBS38_03277 3057011 3057832 - UPF0721 transmembrane protein YunE Belongs to the UPF0721 family gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03277 BSBS38_03278 BSBS38_03278 BSBS38_03278 3057850 3058698 - UPF0759 protein YunF Belongs to the UPF0759 family gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03278 BSBS38_03279 BSBS38_03279 BSBS38_03279 3058736 3059083 - uncharacterized protein gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03279 BSBS38_03280 BSBS38_03280 BSBS38_03280 3059180 3060520 - Dihydroorotase Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring%3B Belongs to the DHOase family. Allantoinase subfamily%3B KEGG: xau:Xaut_1415 dihydroorotase gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03280 BSBS38_03281 BSBS38_03281 BSBS38_03281 3060695 3062290 + Purine catabolism regulatory protein Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03281 BSBS38_03282 BSBS38_03282 BSBS38_03282 3062432 3063784 + Uric acid permease PucJ Uptake of uric acid%3B Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03282 BSBS38_03283 BSBS38_03283 BSBS38_03283 3063790 3065082 + Uric acid permease PucK Uptake of uric acid%3B Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03283 BSBS38_03284 BSBS38_03284 uraD uraD 3065095 3066579 + 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase Catalyzes two steps in the degradation of uric acid%2C i. e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5- ureidoimidazoline (OHCU) to (S)-allantoin%3B In the N-terminal sectio%3B belongs to the OHCU decarboxylase family%3B In the C-terminal sectio%3B belongs to the uricase family%3B KEGG: ctt:CtCNB1_0869 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03284 BSBS38_03285 BSBS38_03285 uraH uraH 3066579 3066923 + Hydroxyisourate hydrolase Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily%3B KEGG: bsu:BSU32460 5-hydroxyisourate hydrolase gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03285 BSBS38_03286 BSBS38_03286 ygeS ygeS 3067683 3068204 - Xanthine dehydrogenase Oxidizes hypoxanthine and xanthine to uric acid%3B Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: bsu:BSU32470 xanthine dehydrogenase molybdenum-binding subunit%3B overlaps another CDS with the same product name gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03286 BSBS38_03287 BSBS38_03287 BSBS38_03287 3068195 3070432 - Xanthine dehydrogenase Oxidizes hypoxanthine and xanthine to uric acid%3B Belongs to the xanthine dehydrogenase family%3B KEGG: bsu:BSU32480 xanthine dehydrogenase molybdenum-binding subunit%3B overlaps another CDS with the same product name gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03287 BSBS38_03288 BSBS38_03288 BSBS38_03288 3070433 3071266 - Xanthine dehydrogenase Oxidizes hypoxanthine and xanthine to uric acid%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bsu:BSU32490 xanthine dehydrogenase molybdenum-binding subunit%3B overlaps another CDS with the same product name gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03288 BSBS38_03289 BSBS38_03289 BSBS38_03289 3071263 3071880 - Xanthine dehydrogenase Required for xanthine dehydrogenase activity. Could be involved in formation of the molybdenum cofactor required by xanthine dehydrogenase%3B KEGG: bsu:BSU32500 xanthine dehydrogenase molybdenum-binding subunit%3B overlaps another CDS with the same product name gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03289 BSBS38_03290 BSBS38_03290 BSBS38_03290 3071877 3072869 - Xanthine dehydrogenase Oxidizes hypoxanthine and xanthine to uric acid. PucA subunit could exert a molybdenum cofactor recruiting function%3B KEGG: bsu:BSU32510 xanthine dehydrogenase molybdenum-binding subunit%3B overlaps another CDS with the same product name gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03290 BSBS38_03291 BSBS38_03291 pucG pucG 3073096 3074346 - Purine catabolism protein PucG Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase%2C or perhaps both activities%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU32520 (S)-ureidoglycine-glyoxylate aminotransferase%3B Transaminases gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03291 BSBS38_03292 BSBS38_03292 allC allC 3074363 3075601 - Allantoate deiminase Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: bsu:BSU32530 allantoate deiminase gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03292 BSBS38_03293 BSBS38_03293 BSBS38_03293 3076043 3076909 + Extracellular ribonuclease Mg(2+)-activated ribonuclease which hydrolyzes RNA apparently nonspecifically into oligonucleotides with 5'-terminal phosphate gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03293 BSBS38_03294 BSBS38_03294 BSBS38_03294 3077088 3078191 - putative ABC transporter ATP-binding protein YurJ Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: pdr:H681_05385 lipopolysaccharide export system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03294 BSBS38_03295 BSBS38_03295 BSBS38_03295 3078373 3079101 + putative HTH-type transcriptional regulator YurK Contains 1 HTH gntR-type DNA-binding domain gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03295 BSBS38_03296 BSBS38_03296 frlD frlD 3079126 3079980 - Fructosamine kinase FrlD Catalyzes the phosphorylation of a range of fructosamines to fructosamine 6-phosphates%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsr:I33_3361 fructoselysine 6-kinase%3B Phosphotransferases with an alcohol group as acceptor gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03296 BSBS38_03297 BSBS38_03297 BSBS38_03297 3079994 3080896 - putative ABC transporter permease protein YurM Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03297 BSBS38_03298 BSBS38_03298 BSBS38_03298 3080900 3081778 - putative ABC transporter permease protein YurN Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03298 BSBS38_03299 BSBS38_03299 BSBS38_03299 3081836 3083104 - putative ABC transporter extracellular-binding protein YurO Probably part of the binding-protein-dependent transport system YurMNO. Belongs to the bacterial solute-binding protein 1 family gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03299 BSBS38_03300 BSBS38_03300 frlB frlB 3083185 3084171 - Fructosamine deglycase FrlB Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid%3B Contains 2 SIS domains%3B KEGG: bsu:BSU32610 fructoselysine 6-phosphate deglycase%3B Acting on carbon-nitrogen bonds%2C other than peptide bonds gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03300 BSBS38_03301 BSBS38_03301 BSBS38_03301 3084386 3084760 - uncharacterized protein Contains 1 GIY-YIG domain gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03301 BSBS38_03302 BSBS38_03302 dadA dadA 3084863 3085981 - D-arginine dehydrogenase Belongs to the DadA oxidoreductase family%3B KEGG: bsu:BSU32630 D-amino-acid dehydrogenase gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03302 BSBS38_03303 BSBS38_03303 BSBS38_03303 3086140 3086286 + Small%2C acid-soluble spore protein gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03303 BSBS38_03304 BSBS38_03304 BSBS38_03304 3086286 3086561 + uncharacterized protein gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03304 BSBS38_03305 BSBS38_03305 BSBS38_03305 3086625 3087008 - uncharacterized protein Belongs to the glyoxalase I family gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03305 BSBS38_03306 BSBS38_03306 BSBS38_03306 3087119 3087397 - putative HTH-type transcriptional regulator YuzN Contains 1 HTH arsR-type DNA-binding domain gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03306 BSBS38_03307 BSBS38_03307 BSBS38_03307 3087661 3089058 - FeS cluster assembly protein SufB The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03307 BSBS38_03308 BSBS38_03308 BSBS38_03308 3089079 3089522 - Zinc-dependent sulfurtransferase SufU Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein (PubMed:20097860%2C PubMed:21236255)%2C but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein (PubMed:24321018). Has been shown to bind low levels of a labile%2C air-sensitive Fe-S cluste%3B this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS%2C for which it acts as a second substrate. Alkylation eliminates its ability to stimulate SufS. A mixture of SufS%2C SufU%2C Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB)%2C reconstituting aconitase activity%3B Belongs to the NifU family gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03308 BSBS38_03309 BSBS38_03309 sufS sufS 3089512 3090732 - Cysteine desulfurase Enzyme able to deliver sulfur to partners involved in Fe-S cluster assembly. Catalyzes the removal of elemental sulfur atoms from L-cysteine to produce L-alanine. Activity is stimulated 40-to 100-fold by SufU%2C which acts as a second substrate for this enzyme following release of Ala%2C and generating SufU. S. A mixture of SufS%2C SufU%2C Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB)%2C reconstituting aconitase activity%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily%3B KEGG: mvs:MVIS_4354 cysteine desulfurase / selenocysteine lyase gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03309 BSBS38_03310 BSBS38_03310 BSBS38_03310 3090732 3092045 - FeS cluster assembly protein SufD The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03310 BSBS38_03311 BSBS38_03311 BSBS38_03311 3092063 3092848 - Vegetative protein 296 Belongs to the ABC transporter superfamily. Ycf16 family%3B Contains 1 ABC transporter domain gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03311 BSBS38_03312 BSBS38_03312 BSBS38_03312 3093373 3093735 - 4-carboxymuconolactone decarboxylase KEGG: gsu:GSU1313 4-carboxymuconolactone decarboxylase gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03312 BSBS38_03313 BSBS38_03313 BSBS38_03313 3093835 3094659 - Methionine-binding lipoprotein MetQ Part of the ABC transporter complex MetNPQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable)%3B Belongs to the NlpA lipoprotein family gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03313 BSBS38_03314 BSBS38_03314 BSBS38_03314 3094673 3095341 - Methionine import system permease protein MetP Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03314 BSBS38_03315 BSBS38_03315 BSBS38_03315 3095334 3096359 - Lipoprotein-releasing system ATP-binding protein LolD Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain%3B KEGG: yen:YE1199 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03315 BSBS38_03316 BSBS38_03316 BSBS38_03316 3096686 3097030 - uncharacterized protein gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03316 BSBS38_03317 BSBS38_03317 BSBS38_03317 3097137 3097457 - Thioredoxin-like protein YusE Contains 1 thioredoxin domain gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03317 BSBS38_03318 BSBS38_03318 BSBS38_03318 3097459 3097899 - uncharacterized protein Contains 1 Toprim domain%3B overlaps another CDS with the same product name gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03318 BSBS38_03319 BSBS38_03319 BSBS38_03319 3097899 3098135 - uncharacterized protein overlaps another CDS with the same product name gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03319 BSBS38_03320 BSBS38_03320 BSBS38_03320 3098191 3098574 - Glycine cleavage system H protein The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein%3B Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate%3B Belongs to the GcvH family%3B Contains 1 lipoyl-binding domain gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03320 BSBS38_03321 BSBS38_03321 BSBS38_03321 3098641 3098997 - Arsenate reductase (glutaredoxin) Belongs to the ArsC family%3B KEGG: bsu:BSU32810 arsenate reductase gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03321 BSBS38_03322 BSBS38_03322 BSBS38_03322 3099108 3100892 - putative acyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bcl:ABC2988 null%3B With other acceptors gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03322 BSBS38_03323 BSBS38_03323 BSBS38_03323 3100907 3102082 - Acetyl-CoA C-acetyltransferase Involved in the degradation of long-chain fatty acids. Belongs to the thiolase family%3B KEGG: spe:Spro_4857 acetyl-CoA C-acetyltransferase gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03323 BSBS38_03324 BSBS38_03324 fadN fadN 3102093 3104462 - 3-hydroxyacyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: bsu:BSU32840 3-hydroxyacyl-CoA dehydrogenase gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03324 BSBS38_03325 BSBS38_03325 BSBS38_03325 3104637 3104783 + uncharacterized protein gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03325 BSBS38_03326 BSBS38_03326 BSBS38_03326 3104808 3105716 - Proline dehydrogenase Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C)%3B Belongs to the proline oxidase family%3B KEGG: bsu:BSU32850 proline dehydrogenase%3B Acting on the CH-NH group of donors gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03326 BSBS38_03327 BSBS38_03327 BSBS38_03327 3105810 3106055 + uncharacterized protein gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03327 BSBS38_03328 BSBS38_03328 BSBS38_03328 3106068 3106400 + uncharacterized protein gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03328 BSBS38_03329 BSBS38_03329 BSBS38_03329 3106559 3107026 + putative HTH-type transcriptional regulator YusO Contains 1 HTH marR-type DNA-binding domain gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03329 BSBS38_03330 BSBS38_03330 BSBS38_03330 3107023 3108648 + putative MFS-type transporter YusP Belongs to the major facilitator superfamily. EmrB family gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03330 BSBS38_03331 BSBS38_03331 BSBS38_03331 3108684 3109067 - 2-hydroxymuconate tautomerase Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: bam:Bamb_3223 4-oxalocrotonate tautomerase gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03331 BSBS38_03332 BSBS38_03332 BSBS38_03332 3109086 3109826 - 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsr:I33_3399 3-oxoacyl-(acyl-carrier protein) reductase gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03332 BSBS38_03333 BSBS38_03333 BSBS38_03333 3109960 3110847 + HTH-type transcriptional regulator YofA Regulates expression of the cell division protein ftsW%2C and is essential for cell viability during stationary phase%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03333 BSBS38_03334 BSBS38_03334 BSBS38_03334 3110867 3111112 - uncharacterized protein gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03334 BSBS38_03335 BSBS38_03335 BSBS38_03335 3111180 3112007 - Iron-chelate-transporting ATPase Provides the ATPase subunit for at least 2 ABC transporter complexe%3B YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen (Probable)%2C and FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable). Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU32940 iron complex transport system ATP-binding protein gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03335 BSBS38_03336 BSBS38_03336 BSBS38_03336 3112225 3112662 - uncharacterized protein gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03336 BSBS38_03337 BSBS38_03337 BSBS38_03337 3112772 3114568 - Oligoendopeptidase F%2C chromosomal Hydrolyzes peptides containing between 7 and 17 amino acids with a rather wide specificity. Belongs to the peptidase M3B family%3B KEGG: aha:AHA_2587 oligoendopeptidase F%3B Metalloendopeptidases gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03337 BSBS38_03338 BSBS38_03338 BSBS38_03338 3115293 3115457 + hypothetical protein gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03338 BSBS38_03339 BSBS38_03339 BSBS38_03339 3115872 3117110 + Transposase for insertion sequence element IS1201 Required for the transposition of the insertion element. Belongs to the transposase mutator family gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03339 BSBS38_03340 BSBS38_03340 BSBS38_03340 3117576 3118652 - Protein EcsB Presumed to form part of an ABC-transporter%2C it may form a transport channel gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03340 BSBS38_03341 BSBS38_03341 BSBS38_03341 3118769 3119494 - Energy-coupling factor transporter ATP-binding protein EcfA ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03341 BSBS38_03342 BSBS38_03342 crtF crtF 3119552 3120658 - Demethylspheroidene O-methyltransferase The N-terminal domain enhances the formation of an early%2C partially cyclized intermediate%2C while the C-terminal domain catalyzes the 3-O-methylation of one or more later intermediates in the biosynthetic pathway. Catalyzes the methylation of tetracenomycin D3 (Tcm D3) to yield Tcm B3. Catalyzes as well the following side reactions: methylation of 8- O-methyl-Tcm D3 to yield Tcm%3B and of 9-carboxymethyl-Tcm B3 to yield Tcm A2. Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O- methyltransferase family%3B KEGG: jan:Jann_0181 demethylspheroidene O-methyltransferase gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03342 BSBS38_03343 BSBS38_03343 BSBS38_03343 3120688 3121929 - hypothetical protein gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03343 BSBS38_03344 BSBS38_03344 BSBS38_03344 3121919 3122443 - hypothetical protein gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03344 BSBS38_03345 BSBS38_03345 BSBS38_03345 3122443 3123777 - hypothetical protein gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03345 BSBS38_03346 BSBS38_03346 BSBS38_03346 3123774 3125066 - hypothetical protein gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03346 BSBS38_03347 BSBS38_03347 BSBS38_03347 3125074 3126357 - hypothetical protein gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03347 BSBS38_03348 BSBS38_03348 BSBS38_03348 3126369 3127631 - Glycine C-acetyltransferase Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bso:BSNT_04905 glycine C-acetyltransferase gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03348 BSBS38_03349 BSBS38_03349 phbB phbB 3128529 3129287 + Acetoacetyl-CoA reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: fau:Fraau_0742 acetoacetyl-CoA reductase gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03349 BSBS38_03350 BSBS38_03350 BSBS38_03350 3129377 3129838 + Metalloregulation DNA-binding stress protein Forms highly stable%2C multimeric protein-DNA complexes which accumulate in stationary-phase cells and protect against oxidative killing. Belongs to the Dps family gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03350 BSBS38_03351 BSBS38_03351 BSBS38_03351 3129882 3131258 - Peptidase Do Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bsu:BSU33000 serine protease Do gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03351 BSBS38_03352 BSBS38_03352 BSBS38_03352 3131536 3132213 + Transcriptional regulatory protein CssR Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03352 BSBS38_03353 BSBS38_03353 cssS cssS 3132210 3133565 + Histidine kinase Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU33020 two-component system%2C OmpR family%2C sensor histidine kinase CssS gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03353 BSBS38_03354 BSBS38_03354 BSBS38_03354 3133593 3133757 - uncharacterized protein gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03354 BSBS38_03355 BSBS38_03355 BSBS38_03355 3133925 3134800 + putative HTH-type transcriptional regulator YuxN Contains 1 HTH tetR-type DNA-binding domain gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03355 BSBS38_03356 BSBS38_03356 BSBS38_03356 3134840 3136228 - Fumarate hydratase Catalyzes the reversible addition of water to fumarate to give L-malate%3B Belongs to the class-II fumarase/aspartase family. Fumarase subfamily%3B KEGG: hin:HI1398 fumarate hydratase%2C class II gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03356 BSBS38_03357 BSBS38_03357 BSBS38_03357 3136295 3136480 - uncharacterized protein gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03357 BSBS38_03358 BSBS38_03358 BSBS38_03358 3136598 3138046 + Spore germination protein A1 Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the GerABKA family gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03358 BSBS38_03359 BSBS38_03359 BSBS38_03359 3138015 3139112 + Spore germination protein A2 Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03359 BSBS38_03360 BSBS38_03360 BSBS38_03360 3139109 3140230 + Spore germination protein A3 Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the GerABKC lipoprotein family gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03360 BSBS38_03361 BSBS38_03361 BSBS38_03361 3140238 3140873 - Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03361 BSBS38_03362 BSBS38_03362 liaS liaS 3140851 3141933 - Histidine kinase Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin%2C nisin%2C ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. Activates probably LiaR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU33090 two-component system%2C NarL family%2C sensor histidine kinase LiaS gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03362 BSBS38_03363 BSBS38_03363 BSBS38_03363 3141930 3142655 - Protein LiaF gene gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03363 BSBS38_03364 BSBS38_03364 BSBS38_03364 3142689 3143561 - Protein LiaG gene gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03364 BSBS38_03365 BSBS38_03365 BSBS38_03365 3143662 3144339 - Protein LiaH Belongs to the PspA/IM30 family gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03365 BSBS38_03366 BSBS38_03366 BSBS38_03366 3144366 3144746 - Protein LiaI gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03366 BSBS38_03367 BSBS38_03367 BSBS38_03367 3144908 3146176 - putative MFS-type transporter YvqJ Belongs to the major facilitator superfamily gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03367 BSBS38_03368 BSBS38_03368 mmaB mmaB 3146353 3146934 - Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase Belongs to the Cob(I)alamin adenosyltransferase family%3B KEGG: bsu:BSU33150 cob(I)alamin adenosyltransferase gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03368 BSBS38_03369 BSBS38_03369 BSBS38_03369 3146957 3148288 - Hemin import ATP-binding protein HmuV Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3. A. 1. 14. 5) family%3B Contains 1 ABC transporter domain gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03369 BSBS38_03370 BSBS38_03370 BSBS38_03370 3148285 3149346 - putative ABC transporter permease protein YvrB Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03370 BSBS38_03371 BSBS38_03371 BSBS38_03371 3149309 3150253 - putative ABC transporter substrate-binding lipoprotein YvrC Probably part of an ABC transporter complex%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03371 BSBS38_03372 BSBS38_03372 BSBS38_03372 3150651 3150941 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: kpk:A593_20530 3-oxoacyl-(acyl-carrier protein) reductase%3B overlaps another CDS with the same product name gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03372 BSBS38_03373 BSBS38_03373 BSBS38_03373 3150938 3151429 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: eco:b1093 3-oxoacyl-(acyl-carrier protein) reductase%3B overlaps another CDS with the same product name gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03373 BSBS38_03374 BSBS38_03374 BSBS38_03374 3151466 3152344 - Gluconolactonase Belongs to the SMP-30/CGR1 family%3B KEGG: spu:575038 gluconolactonase gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03374 BSBS38_03375 BSBS38_03375 BSBS38_03375 3152416 3154158 - Sensor histidine kinase YvrG Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon. Probably activates YvrH by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: ban:BA_1118 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03375 BSBS38_03376 BSBS38_03376 BSBS38_03376 3154155 3154868 - Transcriptional regulatory protein YvrH Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03376 BSBS38_03377 BSBS38_03377 BSBS38_03377 3155020 3155259 - Sigma-O factor regulatory protein RsoA Together with RNA polymerase sigma factor SigO%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress-dependent induction of the oxalate decarboxylase oxdC gene gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03377 BSBS38_03378 BSBS38_03378 BSBS38_03378 3155263 3155835 - RNA polymerase sigma factor SigO Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Together with its coactivator RsoA%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress- dependent induction of the oxalate decarboxylase oxdC%3B Belongs to the sigma-70 factor family gene gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03378 BSBS38_03379 BSBS38_03379 BSBS38_03379 3155995 3156147 + uncharacterized protein gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03379 BSBS38_03380 BSBS38_03380 oxdD oxdD 3156268 3157425 + Oxalate decarboxylase Converts oxalate to formate and CO(2) in an O(2)- dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2)%2C and oxalate-dependent%2C H(2)O(2)-independent dye oxidations%3B To B. subtilis OxdD%3B KEGG: bsu:BSU33240 oxalate decarboxylase gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03380 BSBS38_03381 BSBS38_03381 BSBS38_03381 3157486 3157896 + Membrane-bound negative regulator YvrL Negatively regulates RNA polymerase sigma factor SigO- dependent transcription. Prevents the expression or secretion of OxdC under nonstress conditions. May act as an anti-sigma factor gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03381 BSBS38_03382 BSBS38_03382 BSBS38_03382 3157929 3159179 - putative ABC transporter permease YvrN Belongs to the ABC-4 integral membrane protein family gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03382 BSBS38_03383 BSBS38_03383 BSBS38_03383 3159151 3159840 - Lipoprotein-releasing system ATP-binding protein LolD Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03383 BSBS38_03384 BSBS38_03384 BSBS38_03384 3159824 3161017 - Putative efflux system protein YvrP Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03384 BSBS38_03385 BSBS38_03385 BSBS38_03385 3161188 3161997 - Iron(3+)-hydroxamate import ATP-binding protein FhuC Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Iron (Fe3+)-hydroxamate importer (TC 3. A. 1. 14. 7) family%3B Contains 1 ABC transporter domain gene gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03385 BSBS38_03386 BSBS38_03386 BSBS38_03386 3162013 3163023 - Iron(3+)-hydroxamate import system permease protein FhuG Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03386 BSBS38_03387 BSBS38_03387 BSBS38_03387 3163023 3164069 - Iron(3+)-hydroxamate import system permease protein FhuB Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03387 BSBS38_03388 BSBS38_03388 BSBS38_03388 3164275 3165222 + Iron(3+)-hydroxamate-binding protein FhuD Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03388 BSBS38_03389 BSBS38_03389 BSBS38_03389 3165215 3165457 - hypothetical protein gene gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03389 BSBS38_03390 BSBS38_03390 BSBS38_03390 3165457 3166866 - Putative arginine/ornithine antiporter Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03390 BSBS38_03391 BSBS38_03391 BSBS38_03391 3167266 3167406 - Small%2C acid-soluble spore protein J gene gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03391 BSBS38_03392 BSBS38_03392 BSBS38_03392 3167573 3168055 + uncharacterized protein To E. coli YdjM gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03392 BSBS38_03393 BSBS38_03393 BSBS38_03393 3168155 3170008 + Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Belongs to the LTA synthase family%3B KEGG: bli:BL02415 lipoteichoic acid synthase gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03393 BSBS38_03394 BSBS38_03394 BSBS38_03394 3170036 3170965 - uncharacterized protein gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03394 BSBS38_03395 BSBS38_03395 BSBS38_03395 3171073 3171855 + Putative ABC transporter substrate-binding lipoprotein YvgL Belongs to the bacterial solute-binding protein 1 family gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03395 BSBS38_03396 BSBS38_03396 BSBS38_03396 3171836 3172519 + Putative molybdenum transport system permease protein YvgM could be part of the binding-protein-dependent transport system for molybdenu%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03396 BSBS38_03397 BSBS38_03397 BSBS38_03397 3172550 3173380 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis%3B Belongs to the aldo/keto reductase family%3B KEGG: ece:Z0374 2%2C5-diketo-D-gluconate reductase A gene gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03397 BSBS38_03398 BSBS38_03398 BSBS38_03398 3173603 3174088 + Stress response protein YvgO gene gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03398 BSBS38_03399 BSBS38_03399 BSBS38_03399 3174132 3176144 - Sodium%2C potassium%2C lithium and rubidium/H(+) antiporter Transporter involved in the efflux of sodium%2C potassium%2C lithium and rubidium%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family. Nhak (TC 2. A. 36. 3. 2) subfamily gene gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03399 BSBS38_03400 BSBS38_03400 cysI cysI 3176399 3178114 - Assimilatory sulfite reductase (NADPH) Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (Probable)%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bsu:BSU33430 sulfite reductase (NADPH) hemoprotein beta-component gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03400 BSBS38_03401 BSBS38_03401 cysJ cysJ 3178140 3179957 - Assimilatory sulfite reductase (NADPH) Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component (Probable)%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bsu:BSU33440 sulfite reductase (NADPH) flavoprotein alpha-component gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03401 BSBS38_03402 BSBS38_03402 BSBS38_03402 3180128 3182452 - DNA helicase Catalyzes the unwinding of duplex DNA in the 3' to 5' directio%3B this reaction is dependent on the hydrolysis of ATP%3B Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B KEGG: bsu:BSU33450 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03402 BSBS38_03403 BSBS38_03403 BSBS38_03403 3183030 3183464 + hypothetical protein gene gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03403 BSBS38_03404 BSBS38_03404 BSBS38_03404 3183573 3184184 - UPF0126 membrane protein YvgT Belongs to the UPF0126 family gene gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03404 BSBS38_03405 BSBS38_03405 BSBS38_03405 3184371 3184787 - Disulfide bond formation protein Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168%2C although it can partially substitute for BdbB when the latter is absent. It may also be required for the stability of other secreted proteins. Not required for sporulation%3B Belongs to the DsbB family. BdbC subfamily gene gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03405 BSBS38_03406 BSBS38_03406 BSBS38_03406 3184792 3185460 - Disulfide bond formation protein D Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation%3B Belongs to the thioredoxin family. DsbA subfamily%3B Contains 1 thioredoxin domain gene gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03406 BSBS38_03407 BSBS38_03407 BSBS38_03407 3185580 3187679 - Cadmium-exporting ATPase Couples the hydrolysis of ATP with the transport of cadmium%2C zinc and cobalt out of the cell. Does not seem to transport copper%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 1 HMA domain%3B KEGG: bsu:BSU33490 Cd2+/Zn2+-exporting ATPase gene gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03407 BSBS38_03408 BSBS38_03408 copA copA 3187849 3190263 - Cu(+) exporting ATPase Involved in copper export%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 2 HMA domains%3B KEGG: bsl:A7A1_2568 Cu+-exporting ATPase gene gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03408 BSBS38_03409 BSBS38_03409 BSBS38_03409 3190344 3190553 - Cu(+) exporting ATPase Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Contains 1 HMA domain%3B KEGG: mst:Msp_0224 Cu+-exporting ATPase gene gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03409 BSBS38_03410 BSBS38_03410 BSBS38_03410 3190629 3190934 - Copper-sensing transcriptional repressor CsoR Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions%2C binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions%2C CsoR binds Cu(1+)%2C which significantly decreases its DNA binding affinity and leads to the transcription of the genes%3B Belongs to the CsoR family gene gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03410 BSBS38_03411 BSBS38_03411 iolW iolW 3191092 3192138 + Scyllo-inositol 2-dehydrogenase (NADP(+)) Catalyzes the NADP(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: vej:VEJY3_08950 scyllo-inositol 2-dehydrogenase (NADP+) gene gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03411 BSBS38_03412 BSBS38_03412 BSBS38_03412 3192175 3192810 - FMN-dependent NADH-azoreductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: gur:Gura_1271 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03412 BSBS38_03413 BSBS38_03413 BSBS38_03413 3192970 3194865 - putative membrane protein YvaC Belongs to the YccS/YhfK family gene gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03413 BSBS38_03414 BSBS38_03414 BSBS38_03414 3195031 3195432 - uncharacterized protein gene gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03414 BSBS38_03415 BSBS38_03415 BSBS38_03415 3195429 3195788 - putative membrane protein YvaE Belongs to the small multidrug resistance (SMR) protein family gene gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03415 BSBS38_03416 BSBS38_03416 BSBS38_03416 3195785 3196357 - putative HTH-type transcriptional regulator YvaF Contains 1 HTH tetR-type DNA-binding domain gene gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03416 BSBS38_03417 BSBS38_03417 BSBS38_03417 3196468 3197262 - 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sml:Smlt3653 3-oxoacyl-(acyl-carrier protein) reductase gene gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03417 BSBS38_03418 BSBS38_03418 BSBS38_03418 3197653 3197748 + hypothetical protein gene gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03418 BSBS38_03419 BSBS38_03419 BSBS38_03419 3197766 3197960 + hypothetical protein gene gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03419 BSBS38_03420 BSBS38_03420 BSBS38_03420 3198122 3199705 + Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03420 BSBS38_03421 BSBS38_03421 BSBS38_03421 3199720 3200109 + hypothetical protein gene gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03421 BSBS38_03422 BSBS38_03422 BSBS38_03422 3200299 3201054 + hypothetical protein gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03422 BSBS38_03423 BSBS38_03423 BSBS38_03423 3201094 3202035 - N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bsu:BSU12810 N-acetylmuramoyl-L-alanine amidase gene gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03423 BSBS38_03424 BSBS38_03424 BSBS38_03424 3202077 3202499 - uncharacterized protein Belongs to the Cp-1 holin family gene gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03424 BSBS38_03425 BSBS38_03425 BSBS38_03425 3202553 3202723 - hypothetical protein gene gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03425 BSBS38_03426 BSBS38_03426 BSBS38_03426 3202720 3203019 - SPBc2 prophage-derived uncharacterized protein YomQ gene gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03426 BSBS38_03427 BSBS38_03427 BSBS38_03427 3203035 3204258 - Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03427 BSBS38_03428 BSBS38_03428 BSBS38_03428 3204295 3205869 - hypothetical protein gene gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03428 BSBS38_03429 BSBS38_03429 BSBS38_03429 3205906 3207612 - Lysozyme Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: lpl:lp_1138 lysozyme gene gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03429 BSBS38_03430 BSBS38_03430 BSBS38_03430 3207624 3208463 - hypothetical protein gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03430 BSBS38_03431 BSBS38_03431 BSBS38_03431 3208463 3212341 - Tape measure protein Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03431 BSBS38_03432 BSBS38_03432 BSBS38_03432 3212354 3212518 - hypothetical protein gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03432 BSBS38_03433 BSBS38_03433 BSBS38_03433 3212536 3212874 - hypothetical protein gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03433 BSBS38_03434 BSBS38_03434 BSBS38_03434 3212929 3213540 - hypothetical protein gene gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03434 BSBS38_03435 BSBS38_03435 BSBS38_03435 3213541 3213921 - hypothetical protein gene gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03435 BSBS38_03436 BSBS38_03436 BSBS38_03436 3213918 3214301 - hypothetical protein gene gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03436 BSBS38_03437 BSBS38_03437 BSBS38_03437 3214598 3214945 - hypothetical protein gene gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03437 BSBS38_03438 BSBS38_03438 BSBS38_03438 3214961 3215452 - Fibril-forming collagen alpha chain gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03438 BSBS38_03439 BSBS38_03439 BSBS38_03439 3215481 3215795 - hypothetical protein gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03439 BSBS38_03440 BSBS38_03440 BSBS38_03440 3215811 3217013 - hypothetical protein gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03440 BSBS38_03441 BSBS38_03441 BSBS38_03441 3217050 3217676 - hypothetical protein gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03441 BSBS38_03442 BSBS38_03442 BSBS38_03442 3217666 3218913 - hypothetical protein gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03442 BSBS38_03443 BSBS38_03443 BSBS38_03443 3218919 3219134 - hypothetical protein gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03443 BSBS38_03444 BSBS38_03444 BSBS38_03444 3219183 3220856 - uncharacterized protein Belongs to the phage terminase family gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03444 BSBS38_03445 BSBS38_03445 BSBS38_03445 3220856 3221389 - hypothetical protein gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03445 BSBS38_03446 BSBS38_03446 BSBS38_03446 3221461 3221769 - hypothetical protein gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03446 BSBS38_03447 BSBS38_03447 BSBS38_03447 3221769 3222191 - hypothetical protein gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03447 BSBS38_03448 BSBS38_03448 BSBS38_03448 3222193 3222939 - hypothetical protein gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03448 BSBS38_03449 BSBS38_03449 BSBS38_03449 3223330 3224103 - hypothetical protein gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03449 BSBS38_03450 BSBS38_03450 BSBS38_03450 3224254 3224631 - hypothetical protein gene gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03450 BSBS38_03451 BSBS38_03451 BSBS38_03451 3225319 3225831 - putative integrase/recombinase YoeC Belongs to the 'phage' integrase family gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03451 BSBS38_03452 BSBS38_03452 BSBS38_03452 3225828 3226280 - putative phage-related protein gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03452 BSBS38_03453 BSBS38_03453 BSBS38_03453 3226534 3226734 - hypothetical protein gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03453 BSBS38_03454 BSBS38_03454 BSBS38_03454 3226731 3227150 - SPBc2 prophage-derived uncharacterized protein YopX gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03454 BSBS38_03455 BSBS38_03455 BSBS38_03455 3227147 3227479 - hypothetical protein gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03455 BSBS38_03456 BSBS38_03456 BSBS38_03456 3227479 3228135 - hypothetical protein gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03456 BSBS38_03457 BSBS38_03457 BSBS38_03457 3228253 3228510 - hypothetical protein gene gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03457 BSBS38_03458 BSBS38_03458 BSBS38_03458 3228507 3228914 - hypothetical protein gene gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03458 BSBS38_03459 BSBS38_03459 BSBS38_03459 3228911 3229228 - hypothetical protein gene gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03459 BSBS38_03460 BSBS38_03460 BSBS38_03460 3229225 3229587 - hypothetical protein gene gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03460 BSBS38_03461 BSBS38_03461 BSBS38_03461 3229630 3229827 - uncharacterized protein To B. subtilis XtrA gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03461 BSBS38_03462 BSBS38_03462 BSBS38_03462 3229906 3230061 - hypothetical protein gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03462 BSBS38_03463 BSBS38_03463 BSBS38_03463 3230074 3230214 - hypothetical protein gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03463 BSBS38_03464 BSBS38_03464 BSBS38_03464 3230183 3230353 - hypothetical protein gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03464 BSBS38_03465 BSBS38_03465 BSBS38_03465 3230322 3230870 - hypothetical protein gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03465 BSBS38_03466 BSBS38_03466 BSBS38_03466 3231185 3232012 - hypothetical protein gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03466 BSBS38_03467 BSBS38_03467 BSBS38_03467 3231996 3232877 - hypothetical protein gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03467 BSBS38_03468 BSBS38_03468 BSBS38_03468 3232870 3233088 - hypothetical protein gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03468 BSBS38_03469 BSBS38_03469 BSBS38_03469 3233113 3233304 - hypothetical protein gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03469 BSBS38_03470 BSBS38_03470 BSBS38_03470 3233356 3233559 - hypothetical protein gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03470 BSBS38_03471 BSBS38_03471 BSBS38_03471 3233794 3234192 + hypothetical protein gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03471 BSBS38_03472 BSBS38_03472 BSBS38_03472 3234189 3234281 - hypothetical protein gene gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03472 BSBS38_03473 BSBS38_03473 BSBS38_03473 3234478 3234606 - hypothetical protein gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03473 BSBS38_03474 BSBS38_03474 BSBS38_03474 3234625 3235725 - hypothetical protein gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03474 BSBS38_03475 BSBS38_03475 BSBS38_03475 3235977 3236387 + hypothetical protein gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03475 BSBS38_03476 BSBS38_03476 BSBS38_03476 3236438 3237037 + ICEBs1 integrase Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome%2C attB%2C and a site in the circular form of ICEBs1%2C attICEBs1%3B Belongs to the 'phage' integrase family gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03476 BSBS38_03477 BSBS38_03477 BSBS38_03477 3237650 3238120 - SsrA-binding protein Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA)%2C required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape%2C replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gen%3B the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide'%2C a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA%2C entering the A-site of stalled ribosomes%2C displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRN%3B the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation%2C which seems to be the essential function of trans- translation%3B Belongs to the SmpB family gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03477 BSBS38_03478 BSBS38_03478 vacB vacB 3238265 3240604 - Ribonuclease 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs%3B Belongs to the RNR ribonuclease family. RNase R subfamily%3B Contains 1 S1 motif domain%3B KEGG: bsu:BSU33610 ribonuclease R%3B Acting on ester bonds gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03478 BSBS38_03479 BSBS38_03479 yvaK yvaK 3240623 3241363 - Carboxylesterase Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates%2C with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones (By similarity)%3B Belongs to the lipase/esterase LIP3/BchO family%3B KEGG: bsu:BSU33620 carboxylesterase gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03479 BSBS38_03480 BSBS38_03480 BSBS38_03480 3241495 3241725 - putative protein-export membrane protein SecG Involved in protein export. Participates in an early event of protein translocation (By similarity)%3B Belongs to the SecG family gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03480 BSBS38_03481 BSBS38_03481 BSBS38_03481 3241874 3242017 + AB hydrolase superfamily protein Belongs to the AB hydrolase superfamily gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03481 BSBS38_03482 BSBS38_03482 BSBS38_03482 3242014 3242646 + 3-oxoadipate enol-lactonase Belongs to the AB hydrolase superfamily%3B KEGG: rpj:N234_00525 3-oxoadipate enol-lactonase gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03482 BSBS38_03483 BSBS38_03483 BSBS38_03483 3242680 3242922 - putative HTH-type transcriptional regulator YvzC Contains 1 HTH cro/C1-type DNA-binding domain gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03483 BSBS38_03484 BSBS38_03484 BSBS38_03484 3243044 3243472 + HTH-type transcriptional repressor RghR Represses the expression of yvaM and both rapG and rapH. Binds directly to the promoter regions of yvaM%2C rapG and rapH%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03484 BSBS38_03485 BSBS38_03485 BSBS38_03485 3243502 3243921 + Repressor LexA Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: aac:Aaci_2954 repressor LexA gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03485 BSBS38_03486 BSBS38_03486 BSBS38_03486 3244013 3244339 + putative HTH-type transcriptional regulator YvaP Contains 1 HTH hxlR-type DNA-binding domain gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03486 BSBS38_03487 BSBS38_03487 BSBS38_03487 3244467 3246167 + Putative sensory transducer protein YvaQ Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation (By similarity)%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03487 BSBS38_03488 BSBS38_03488 BSBS38_03488 3246208 3246888 - Choline transport system permease protein OpuBD Involved in a high affinity multicomponent binding- protein-dependent transport system for cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03488 BSBS38_03489 BSBS38_03489 BSBS38_03489 3246905 3247825 - Choline-binding protein Member of a high affinity multicomponent binding- protein-dependent transport system for choline%3B Belongs to the OsmX family gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03489 BSBS38_03490 BSBS38_03490 BSBS38_03490 3247837 3248490 - Choline transport system permease protein OpuBB Involved in a high affinity multicomponent binding- protein-dependent transport system for cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03490 BSBS38_03491 BSBS38_03491 BSBS38_03491 3248507 3249652 - Iron-chelate-transporting ATPase Involved in a high affinity multicomponent binding- protein-dependent transport system for choline. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: spe:Spro_0548 iron complex transport system ATP-binding protein gene gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03491 BSBS38_03492 BSBS38_03492 BSBS38_03492 3249936 3250469 + Putative HTH-type transcriptional regulator YvaV Belongs to the GbsR family gene gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03492 BSBS38_03493 BSBS38_03493 BSBS38_03493 3250501 3251175 - Glycine betaine/carnitine/choline transport system permease protein OpuCD Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine and cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03493 BSBS38_03494 BSBS38_03494 BSBS38_03494 3251193 3252110 - Glycine betaine/carnitine/choline-binding protein OpuCC Member of a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine%2C and choline%3B Belongs to the OsmX family gene gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03494 BSBS38_03495 BSBS38_03495 BSBS38_03495 3252124 3252777 - Glycine betaine/carnitine/choline transport system permease protein OpuCB Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine and cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03495 BSBS38_03496 BSBS38_03496 BSBS38_03496 3252800 3253942 - Energy-coupling factor transporter ATP-binding protein EcfA ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03496 BSBS38_03497 BSBS38_03497 BSBS38_03497 3254206 3254763 + HTH-type transcriptional repressor OpcR Negatively regulates the transcription of the opuC operon. In the absence of GbsR%2C is also a negative regulator of the opuB operon. Binds to an inverted repeat in the promoter region of the operons%3B Belongs to the GbsR family gene gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03497 BSBS38_03498 BSBS38_03498 BSBS38_03498 3254781 3255413 - UPF0056 membrane protein YvbG Belongs to the UPF0056 (MarC) family gene gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03498 BSBS38_03499 BSBS38_03499 BSBS38_03499 3255566 3256180 + uncharacterized protein gene gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03499 BSBS38_03500 BSBS38_03500 BSBS38_03500 3256311 3257009 + uncharacterized protein gene gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03500 BSBS38_03501 BSBS38_03501 BSBS38_03501 3257045 3258862 - putative membrane protein YvbJ gene gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03501 BSBS38_03502 BSBS38_03502 BSBS38_03502 3258988 3259449 + Inositol-phosphate phosphatase Probable N-acetyltransferase. Contains 1 N-acetyltransferase domain%3B KEGG: eat:EAT1b_2794 myo-inositol-1(or 4)-monophosphatase gene gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03502 BSBS38_03503 BSBS38_03503 BSBS38_03503 3259502 3260794 - Phosphopyruvate hydratase Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis%3B Belongs to the enolase family%3B KEGG: bsu:BSU33900 enolase gene gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03503 BSBS38_03504 BSBS38_03504 gpmI gpmI 3260824 3262359 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate%3B Belongs to the BPG-independent phosphoglycerate mutase family%3B KEGG: fbl:Fbal_3756 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase gene gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03504 BSBS38_03505 BSBS38_03505 tpiA tpiA 3262352 3263113 - Triose-phosphate isomerase Belongs to the triosephosphate isomerase family%3B KEGG: mej:Q7A_2894 triosephosphate isomerase (TIM) gene gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03505 BSBS38_03506 BSBS38_03506 BSBS38_03506 3263144 3264328 - Phosphoglycerate kinase Belongs to the phosphoglycerate kinase family%3B KEGG: sat:SYN_01396 phosphoglycerate kinase gene gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03506 BSBS38_03507 BSBS38_03507 BSBS38_03507 3264645 3265652 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03507 BSBS38_03508 BSBS38_03508 BSBS38_03508 3265699 3266721 - Central glycolytic protein regulator In the absence of glucose%2C represses the transcription of the gapA operon%2C which encodes five key glycolytic enzymes. Binds specifically to the cggR-gapA promoter region and blocks the progression of the RNA polymerase%2C leading to the arrest of the transcription%3B Belongs to the SorC transcriptional regulatory family gene gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03508 BSBS38_03509 BSBS38_03509 BSBS38_03509 3267019 3268413 - Arabinose-proton symporter Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03509 BSBS38_03510 BSBS38_03510 BSBS38_03510 3268617 3269705 + Arabinose metabolism transcriptional repressor Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene%2C and to one sequence in the araR promoter. Contains 1 HTH gntR-type DNA-binding domain gene gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03510 BSBS38_03511 BSBS38_03511 BSBS38_03511 3269754 3270764 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03511 BSBS38_03512 BSBS38_03512 BSBS38_03512 3270921 3271799 - putative HTH-type transcriptional regulator YvbU Contains 1 HTH lysR-type DNA-binding domain gene gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03512 BSBS38_03513 BSBS38_03513 BSBS38_03513 3271899 3272816 + putative transporter YvbV Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03513 BSBS38_03514 BSBS38_03514 BSBS38_03514 3272857 3274200 - putative amino acid permease YvbW May participate in leucine metabolism. May transport leucine or a compound related to leucine metabolism%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03514 BSBS38_03515 BSBS38_03515 BSBS38_03515 3274596 3275630 - putative glycosylase YvbX Belongs to the glycosyl hydrolase 18 family gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03515 BSBS38_03516 BSBS38_03516 BSBS38_03516 3275737 3276459 - Lactate utilization protein Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation%2C since it contributes to the formation of architecturally complex communities when lactate is present%3B Belongs to the LutC/YkgG family%3B overlaps another CDS with the same product name gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03516 BSBS38_03517 BSBS38_03517 BSBS38_03517 3276459 3277898 - Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate%3B Belongs to the LutB/YkgF family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B overlaps another CDS with the same product name gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03517 BSBS38_03518 BSBS38_03518 BSBS38_03518 3277925 3278641 - Lactate utilization protein A Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutA/YkgE family gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03518 BSBS38_03519 BSBS38_03519 BSBS38_03519 3278816 3279433 - hypothetical protein gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03519 BSBS38_03520 BSBS38_03520 BSBS38_03520 3279430 3279759 - hypothetical protein gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03520 BSBS38_03521 BSBS38_03521 BSBS38_03521 3279882 3280484 - putative transcriptional regulatory protein YvfU Member of the two-component regulatory system YvfT/YvfU%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03521 BSBS38_03522 BSBS38_03522 BSBS38_03522 3280501 3281616 - Histidine kinase Member of the two-component regulatory system YvfT/YvfU. Probably activates YvfU by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsr:I33_3525 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03522 BSBS38_03523 BSBS38_03523 BSBS38_03523 3281620 3282357 - Putative transport permease YvfS Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03523 BSBS38_03524 BSBS38_03524 BSBS38_03524 3282358 3283260 - Polar-amino-acid-transporting ATPase Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: eca:ECA0854 polar amino acid transport system ATP-binding protein gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03524 BSBS38_03525 BSBS38_03525 BSBS38_03525 3283664 3284182 + Adenylate kinase KEGG: aal:EP13_18175 adenylate kinase gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03525 BSBS38_03526 BSBS38_03526 BSBS38_03526 3284200 3285234 + hypothetical protein gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03526 BSBS38_03527 BSBS38_03527 BSBS38_03527 3285212 3285631 + 50S ribosomal protein L22 This protein binds specifically to 23S rRN%3B its binding is stimulated by other ribosomal proteins%2C e. g. L4%2C L17%2C and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)%3B The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit%2C while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome%3B Belongs to the ribosomal protein L22P family gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03527 BSBS38_03528 BSBS38_03528 BSBS38_03528 3285861 3286670 + 3-oxoadipate enol-lactonase Positive regulator required for energy stress activation of the sigma-B transcription factor. Could be required for RsbP phosphatase activity%3B Belongs to the AB hydrolase superfamily%3B KEGG: tmo:TMO_2870 3-oxoadipate enol-lactonase gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03528 BSBS38_03529 BSBS38_03529 BSBS38_03529 3286706 3287917 + Protein-serine/threonine phosphatase Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to energy stress. Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU34110 protein phosphatase gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03529 BSBS38_03530 BSBS38_03530 BSBS38_03530 3287971 3289260 - Arabinogalactan endo-beta-1%2C4-galactanase Hydrolyzes the beta-1%2C4-galactan linkages of arabinogalactan type I%2C a pectic substance found in plants such as soybeans%3B Belongs to the glycosyl hydrolase 53 family%3B KEGG: bsu:BSU34120 arabinogalactan endo-1%2C4-beta-galactosidase gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03530 BSBS38_03531 BSBS38_03531 bgaB bgaB 3289340 3291400 - Beta-galactosidase Hydrolyzes oligosaccharides released by the endo-1%2C4- beta-galactosidase GalA from arabinogalactan type I%2C a pectic plant polysaccharide. It is unable to use lactose as a sole carbon source (By similarity). Catalyzes the hydrolysis of lactose to its constituent monosaccharides glucose and galactose. Possesses a low level of transgalactosylation activity for the production of galacto-oligosaccharides (GOS) from lactose%3B Belongs to the glycosyl hydrolase 42 family%3B KEGG: bsu:BSU34130 beta-galactosidase gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03531 BSBS38_03532 BSBS38_03532 BSBS38_03532 3291422 3292273 - Putative arabinogalactan oligomer transport system permease protein GanQ Could be part of a binding-protein-dependent transport system for arabinogalactan oligomer%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03532 BSBS38_03533 BSBS38_03533 BSBS38_03533 3292277 3293536 - Putative arabinogalactan oligomer transport system permease protein GanP Could be part of a binding-protein-dependent transport system for arabinogalactan oligomer%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03533 BSBS38_03534 BSBS38_03534 BSBS38_03534 3293573 3294808 - Cyclodextrin-binding protein Binding protein for cyclodextri%3B involved in its cellular uptake. Interacts with all natural cyclodextrins: alpha%2C beta and gamma%3B Belongs to the bacterial solute-binding protein 1 family gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03534 BSBS38_03535 BSBS38_03535 BSBS38_03535 3294973 3295971 - HTH-type transcriptional regulator EbgR Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. Contains 1 HTH lacI-type DNA-binding domain gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03535 BSBS38_03536 BSBS38_03536 BSBS38_03536 3296151 3296873 - Exu regulon transcriptional regulator Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT%2C UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. Contains 1 HTH gntR-type DNA-binding domain gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03536 BSBS38_03537 BSBS38_03537 BSBS38_03537 3297101 3298792 + L-lactate permease Is the principal permease for the uptake of L-lactate in B. subtilis%3B Belongs to the lactate permease family gene gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03537 BSBS38_03538 BSBS38_03538 BSBS38_03538 3298819 3300129 - RNA polymerase sigma-54 factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the levanase operon. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein LevR for the expression of the levanase operon. Belongs to the sigma-54 factor family gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03538 BSBS38_03539 BSBS38_03539 BSBS38_03539 3300208 3300426 + uncharacterized protein gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03539 BSBS38_03540 BSBS38_03540 epsO epsO 3300436 3301404 - Putative pyruvyl transferase EpsO May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bsu:BSU34220 pyruvyl transferase EpsO%3B Transferases gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03540 BSBS38_03541 BSBS38_03541 epsN epsN 3301383 3302549 - Putative pyridoxal phosphate-dependent aminotransferase EpsN May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: bsu:BSU34230 pyridoxal phosphate-dependent aminotransferase EpsN%3B Transaminases gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03541 BSBS38_03542 BSBS38_03542 epsM epsM 3302554 3303204 - Putative acetyltransferase EpsM May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the transferase hexapeptide repeat family%3B KEGG: bsu:BSU34240 acetyltransferase EpsM%3B Transferring groups other than amino-acyl groups gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03542 BSBS38_03543 BSBS38_03543 pglC pglC 3303201 3303809 - Undecaprenyl phosphate N%2CN'-diacetylbacillosamine 1-phosphatetransferase May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the bacterial sugar transferase family%3B KEGG: ftn:FTN_1429 undecaprenyl phosphate N%2CN'-diacetylbacillosamine 1-phosphate transferase gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03543 BSBS38_03544 BSBS38_03544 BSBS38_03544 3303806 3305323 - putative membrane protein EpsK gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03544 BSBS38_03545 BSBS38_03545 wapR wapR 3305320 3306354 - putative glycosyltransferase EpsJ May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the glycosyltransferase 2 family%3B KEGG: pso:PSYCG_03430 alpha-1%2C3-rhamnosyltransferase%3B Hexosyltransferases gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03545 BSBS38_03546 BSBS38_03546 epsI epsI 3306351 3307427 - Putative pyruvyl transferase EpsI May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bsu:BSU34290 pyruvyl transferase EpsI%3B Transferases gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03546 BSBS38_03547 BSBS38_03547 epsH epsH 3307432 3308466 - Putative glycosyltransferase EpsH May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance%3B Belongs to the glycosyltransferase 2 family%3B KEGG: bsu:BSU34300 glycosyltransferase EpsH%3B Glycosyltransferases gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03547 BSBS38_03548 BSBS38_03548 BSBS38_03548 3308491 3309594 - Transmembrane protein EpsG gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03548 BSBS38_03549 BSBS38_03549 epsF epsF 3309591 3310745 - Putative glycosyltransferase EpsF May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bsu:BSU34320 glycosyltransferase EpsF%3B Glycosyltransferases gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03549 BSBS38_03550 BSBS38_03550 epsE epsE 3310738 3311574 - Putative glycosyltransferase EpsE May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase 2 family%3B KEGG: bsu:BSU34330 glycosyltransferase EpsE%3B Glycosyltransferases gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03550 BSBS38_03551 BSBS38_03551 epsD epsD 3311571 3312716 - Putative glycosyltransferase EpsD May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bsu:BSU34340 glycosyltransferase EpsD%3B Glycosyltransferases gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03551 BSBS38_03552 BSBS38_03552 BSBS38_03552 3312728 3314524 - putative polysaccharide biosynthesis protein EpsC Involved in biofilm formation%3B Belongs to the polysaccharide synthase family gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03552 BSBS38_03553 BSBS38_03553 epsB epsB 3314783 3315466 - Non-specific protein-tyrosine kinase Belongs to the CpsD/CapB family%3B KEGG: bso:BSNT_05192 protein-tyrosine kinase gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03553 BSBS38_03554 BSBS38_03554 BSBS38_03554 3315472 3316176 - uncharacterized protein Belongs to the CpsC/CapA family gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03554 BSBS38_03555 BSBS38_03555 BSBS38_03555 3316422 3316880 + HTH-type transcriptional regulator SlrR Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03555 BSBS38_03556 BSBS38_03556 pnbA pnbA 3316955 3318424 + Para-nitrobenzyl esterase Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol. Belongs to the type-B carboxylesterase/lipase family%3B KEGG: bsu:BSU34390 para-nitrobenzyl esterase%3B Carboxylic ester hydrolases gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03556 BSBS38_03557 BSBS38_03557 BSBS38_03557 3318427 3318618 + hypothetical protein gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03557 BSBS38_03558 BSBS38_03558 BSBS38_03558 3318645 3319130 - Phenolic acid decarboxylase PadC Involved in the decarboxylation and detoxification of phenolic derivatives. It is able to catalyze the decarboxylation of ferulic%2C p-coumaric and caffeic acids%3B Belongs to the PadC family%3B KEGG: pva:Pvag_pPag30446 phenolic acid decarboxylase%3B Carboxy-lyases gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03558 BSBS38_03559 BSBS38_03559 BSBS38_03559 3319153 3319614 - UPF0311 protein YveG Belongs to the UPF0311 family gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03559 BSBS38_03560 BSBS38_03560 BSBS38_03560 3319710 3320393 - Aspartate racemase Probable aspartate or glutamate racemase involved in peptidoglycan modification during cortex synthesis. Belongs to the aspartate/glutamate racemases family%3B KEGG: bsu:BSU34430 aspartate racemase gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03560 BSBS38_03561 BSBS38_03561 BSBS38_03561 3320409 3320603 - Penicillin-binding protein 4* Probably involved in peptidoglycan modification during cortex synthesis. Belongs to the beta-lactamase family%3B overlaps another CDS with the same product name gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03561 BSBS38_03562 BSBS38_03562 BSBS38_03562 3320600 3321763 - Penicillin-binding protein 4* Probably involved in peptidoglycan modification during cortex synthesis. Belongs to the beta-lactamase family%3B overlaps another CDS with the same product name gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03562 BSBS38_03563 BSBS38_03563 sacB sacB 3322302 3323723 + Levansucrase Belongs to the glycosyl hydrolase 68 family%3B KEGG: bsu:BSU34450 levansucrase gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03563 BSBS38_03564 BSBS38_03564 levB levB 3323797 3325347 + 2%2C6-beta-fructan 6-levanbiohydrolase Catalyzes the degradation of levan mainly into levanbiose (difructose). Is not active on sucrose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bsu:BSU34460 levanbiose-producing levanase gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03564 BSBS38_03565 BSBS38_03565 BSBS38_03565 3325453 3327015 + Aspartate-proton symporter Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency. Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2. A. 3. 11) family gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03565 BSBS38_03566 BSBS38_03566 BSBS38_03566 3327110 3327694 + putative HTH-type transcriptional regulator YvdT Contains 1 HTH tetR-type DNA-binding domain gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03566 BSBS38_03567 BSBS38_03567 BSBS38_03567 3327776 3328111 + putative membrane protein YvdS Belongs to the small multidrug resistance (SMR) protein family gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03567 BSBS38_03568 BSBS38_03568 BSBS38_03568 3328111 3328431 + Quaternary ammonium compound-resistance protein SugE Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium%2C cetyldimethylethyl ammonium and cetrimide cations (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2. A. 7. 1. 4) subfamily gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03568 BSBS38_03569 BSBS38_03569 BSBS38_03569 3328467 3328889 - uncharacterized protein gene gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03569 BSBS38_03570 BSBS38_03570 BSBS38_03570 3329134 3329209 - tRNA-Arg tRNA gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03570 BSBS38_03571 BSBS38_03571 BSBS38_03571 3329479 3330072 + Endopeptidase Clp Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: eco:b0437 ATP-dependent Clp protease%2C protease subunit gene gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03571 BSBS38_03572 BSBS38_03572 BSBS38_03572 3330135 3330809 - Phosphorylated carbohydrates phosphatase Displays high phosphatase activity toward erythrose 4- phosphate%2C fructose 6-phosphate%2C 2-deoxyglucose 6-phosphate%2C and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates%3B Belongs to the HAD-like hydrolase superfamily gene gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03572 BSBS38_03573 BSBS38_03573 BSBS38_03573 3330806 3332491 - Alpha-glucosidase Hydrolyzes various disaccharides such as sucrose%2C maltose%2C and isomaltose with different efficiencies. Also hydrolyzes longer maltodextrins from maltotriose up to maltohexaose%2C but not maltoheptaose%2C palatinose%2C isomaltotriose%2C or isomaltotetraose. Belongs to the glycosyl hydrolase 13 family%3B KEGG: rah:Rahaq_2679 alpha-glucosidase gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03573 BSBS38_03574 BSBS38_03574 mapA mapA 3332484 3334757 - Maltose phosphorylase Catalyzes the phosphorolysis of maltose%2C leading to the formation of glucose and glucose 1-P%3B Belongs to the glycosyl hydrolase 65 family%3B KEGG: bsu:BSU34570 maltose phosphorylase gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03574 BSBS38_03575 BSBS38_03575 BSBS38_03575 3335019 3335615 - Putative maltodextrin utilization protein YvdJ gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03575 BSBS38_03576 BSBS38_03576 BSBS38_03576 3335615 3336451 - Maltodextrin transport system permease protein MdxG Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03576 BSBS38_03577 BSBS38_03577 BSBS38_03577 3336452 3337759 - Maltodextrin transport system permease protein MdxF Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03577 BSBS38_03578 BSBS38_03578 BSBS38_03578 3337800 3339053 - Maltodextrin-binding protein MdxE Part of the ABC transporter complex involved in maltodextrin import. Binds maltodextrin. Can also bind maltose with low affinity%2C but is not involved in its uptake%3B Belongs to the bacterial solute-binding protein 1 family gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03578 BSBS38_03579 BSBS38_03579 BSBS38_03579 3339149 3340912 - Glucan 1%2C4-alpha-maltohydrolase Hydrolyzes beta-cyclodextrin to maltose and glucose%2C soluble starch to maltose and glucose%2C and pullulan to panose with trace amounts of maltose and glucose. It is also able to hydrolyze acarbose. Can also exhibit a transglycosylation activity transferring glucose or maltose to another moiety of sugars by forming alpha-(1%2C6)- and alpha-(1%2C3)-glycosidic linkages upon the hydrolysis of substrate at concentrations of 5%25 or higher%3B Belongs to the glycosyl hydrolase 13 family. BbmA subfamily%3B KEGG: bld:BLi00658 null gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03579 BSBS38_03580 BSBS38_03580 BSBS38_03580 3341028 3341978 - putative HTH-type transcriptional regulator YvdE Contains 1 HTH lacI-type DNA-binding domain gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03580 BSBS38_03581 BSBS38_03581 BSBS38_03581 3342184 3342759 - LOG family protein YvdD Belongs to the LOG family gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03581 BSBS38_03582 BSBS38_03582 BSBS38_03582 3342988 3343197 + uncharacterized protein gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03582 BSBS38_03583 BSBS38_03583 BSBS38_03583 3343224 3344816 - Putative sulfate transporter YvdB Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03583 BSBS38_03584 BSBS38_03584 BSBS38_03584 3344835 3345419 - Carbonate dehydratase Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: bsu:BSU34670 carbonic anhydrase gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03584 BSBS38_03585 BSBS38_03585 BSBS38_03585 3345814 3346788 + Gluconate 2-dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: bsu:BSU34680 gluconate 2-dehydrogenase gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03585 BSBS38_03586 BSBS38_03586 BSBS38_03586 3346825 3348765 - putative ABC transporter permease YvcS Belongs to the ABC-4 integral membrane protein family gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03586 BSBS38_03587 BSBS38_03587 BSBS38_03587 3348740 3349519 - putative ABC transporter ATP-binding protein YvcR Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03587 BSBS38_03588 BSBS38_03588 BSBS38_03588 3349602 3350672 - Sensor histidine kinase YvcQ Member of the two-component regulatory system YvcQ/YvcP. Probably activates YvcP by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU34710 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03588 BSBS38_03589 BSBS38_03589 BSBS38_03589 3350666 3351379 - Sensory transduction protein BceR Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS%2C binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03589 BSBS38_03590 BSBS38_03590 BSBS38_03590 3351526 3351858 + putative lipoprotein YvzJ gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03590 BSBS38_03591 BSBS38_03591 nhoA nhoA 3351770 3352525 - N-hydroxyarylamine O-acetyltransferase Belongs to the arylamine N-acetyltransferase family%3B KEGG: bsu:BSU34730 N-hydroxyarylamine O-acetyltransferase gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03591 BSBS38_03592 BSBS38_03592 BSBS38_03592 3352535 3352792 - HPr-like protein Crh Along with seryl-phosphorylated HPr%2C phosphorylated Crh is implicated in carbon catabolite repression (CCR) of levanase%2C inositol dehydrogenase%2C and beta-xylosidase. Exerts its effect on CCR by interacting with CcpA%3B Belongs to the HPr family%3B Contains 1 HPr domain gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03592 BSBS38_03593 BSBS38_03593 BSBS38_03593 3352816 3353778 - Putative sporulation transcription regulator WhiA May be required for sporulation%3B Belongs to the WhiA transcriptional regulatory family gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03593 BSBS38_03594 BSBS38_03594 BSBS38_03594 3353788 3354783 - Gluconeoproteinis factor Required for morphogenesis under gluconeogenic growth conditions. Required%2C in gluconeogenic growth conditions%2C for the correct localization of PBP1 and hence for displaying a normal rod shape%3B Belongs to the gluconeogenesis factor family gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03594 BSBS38_03595 BSBS38_03595 BSBS38_03595 3354743 3355630 - Nucleotide-binding protein YvcJ Displays ATPase and GTPase activities. Can also hydrolyze pNPP. May affect the expression of competence via the phosphorylation of a cellular component%3B Belongs to the RapZ-like family gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03595 BSBS38_03596 BSBS38_03596 BSBS38_03596 3355655 3356131 - 8-oxo-dGTP diphosphatase Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU34780 8-oxo-dGTP diphosphatase gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03596 BSBS38_03597 BSBS38_03597 BSBS38_03597 3356471 3357400 - Thioredoxin-disulfide reductase Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: rsl:RPSI07_mp0554 thioredoxin reductase (NADPH) gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03597 BSBS38_03598 BSBS38_03598 BSBS38_03598 3357606 3359015 - Peptidoglycan DL-endopeptidase CwlO The C-terminal part of CwlO shows a cell wall hydrolytic DL-endopeptidase activity. Belongs to the peptidase C40 family gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03598 BSBS38_03599 BSBS38_03599 BSBS38_03599 3359395 3360849 - TPR repeat-containing protein YvcD Contains 3 TPR repeats gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03599 BSBS38_03600 BSBS38_03600 abcA abcA 3360975 3362744 - Xenobiotic-transporting ATPase An efflux transporter able to transport Hoechst 33342%2C ethidium bromide%2C doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation (PubMed:18215075). Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU34820 ATP-binding cassette%2C subfamily B%2C bacterial AbcA/BmrA gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03600 BSBS38_03601 BSBS38_03601 BSBS38_03601 3362911 3363270 - uncharacterized protein gene gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03601 BSBS38_03602 BSBS38_03602 BSBS38_03602 3363285 3365192 - Putative uncharacterized protein YvcB gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03602 BSBS38_03603 BSBS38_03603 BSBS38_03603 3365198 3365920 - Putative lipoprotein YvcA Required for complex colony architecture gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03603 BSBS38_03604 BSBS38_03604 BSBS38_03604 3366166 3366795 - Phosphoribosyl-ATP diphosphatase In the N-terminal sectio%3B belongs to the PRA-CH family%3B In the C-terminal sectio%3B belongs to the PRA-PH family%3B KEGG: bsu:BSU34860 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03604 BSBS38_03605 BSBS38_03605 hisF hisF 3366792 3367550 - Imidazole glycerol phosphate synthase subunit HisF IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit%3B Belongs to the HisA/HisF family%3B KEGG: xfa:XF2214 cyclase%3B Oxo-acid-lyases gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03605 BSBS38_03606 BSBS38_03606 hisA hisA 3367547 3368284 - 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamideisomerase Belongs to the HisA/HisF family%3B KEGG: bsu:BSU34880 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03606 BSBS38_03607 BSBS38_03607 hisH hisH 3368281 3368919 - Imidazole glycerol phosphate synthase subunit HisH IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: cff:CFF8240_1352 glutamine amidotransferase%3B Pentosyltransferases gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03607 BSBS38_03608 BSBS38_03608 hisB hisB 3368920 3369504 - Imidazoleglycerol-phosphate dehydratase Belongs to the imidazoleglycerol-phosphate dehydratase family%3B KEGG: nit:NAL212_0816 imidazoleglycerol-phosphate dehydratase gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03608 BSBS38_03609 BSBS38_03609 hisD hisD 3369501 3370784 - Histidinol dehydrogenase Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine%3B Belongs to the histidinol dehydrogenase family%3B KEGG: bsu:BSU34910 histidinol dehydrogenase gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03609 BSBS38_03610 BSBS38_03610 hisG hisG 3370781 3371422 - ATP phosphoribosyltransferase Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity%3B Belongs to the ATP phosphoribosyltransferase family. Short subfamily%3B KEGG: bsu:BSU34920 ATP phosphoribosyltransferase gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03610 BSBS38_03611 BSBS38_03611 BSBS38_03611 3371415 3372590 - ATP phosphoribosyltransferase regulatory subunit Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine%3B Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03611 BSBS38_03612 BSBS38_03612 BSBS38_03612 3372841 3373593 + uncharacterized protein gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03612 BSBS38_03613 BSBS38_03613 pelC pelC 3373833 3374498 + Pectate lyase Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%25%2C with an endo mode of action. In contrast to the majority of pectate lyases%2C displays high activity on highly methylated pectins. Is also able to cleave trigalacturonate to galacturonic acid and unsaturated digalacturonate%3B Belongs to the polysaccharide lyase 3 family%3B KEGG: bsu:BSU34950 pectate lyase C gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03613 BSBS38_03614 BSBS38_03614 lacA lacA 3374518 3375036 - Galactoside O-acetyltransferase Belongs to the transferase hexapeptide repeat family%3B KEGG: nph:NP_4198A galactoside O-acetyltransferase gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03614 BSBS38_03615 BSBS38_03615 ppaX ppaX 3375040 3375690 - Inorganic diphosphatase Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool%3B Belongs to the HAD-like hydrolase superfamily. PpaX family%3B KEGG: bsu:BSU34970 pyrophosphatase PpaX gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03615 BSBS38_03616 BSBS38_03616 BSBS38_03616 3375687 3376625 - putative membrane protein YvoD gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03616 BSBS38_03617 BSBS38_03617 umpA umpA 3376649 3377458 - Prolipoprotein diacylglyceryl transferase Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins. Required for spore germination. Belongs to the Lgt family%3B KEGG: bsu:BSU34990 phosphatidylglycerol:prolipoprotein diacylglycerol transferase%3B Transferases gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03617 BSBS38_03618 BSBS38_03618 hprK hprK 3377472 3378404 - HPr kinase/phosphorylase Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr%2C a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing%2C inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites%2C which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose%2C fructose%2C etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore%2C by controlling the phosphorylation state of HPr and crh%2C HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR)%2C and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion%3B Belongs to the HPrK/P family%3B KEGG: bsu:BSU35000 HPr kinase/phosphorylase%3B Protein-serine/threonine kinases gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03618 BSBS38_03619 BSBS38_03619 BSBS38_03619 3378586 3379776 + N-acetylglucosamine-6-phosphate deacetylase Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N- acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate%3B Belongs to the NagA family%3B KEGG: bsu:BSU35010 N-acetylglucosamine-6-phosphate deacetylase gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03619 BSBS38_03620 BSBS38_03620 BSBS38_03620 3379773 3380501 + Glucosamine-6-phosphate deaminase Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion%3B Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily%3B KEGG: bsu:BSU35020 glucosamine-6-phosphate deaminase gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03620 BSBS38_03621 BSBS38_03621 BSBS38_03621 3380519 3381250 + HTH-type transcriptional repressor YvoA Acts as a weak repressor of yflG expression%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03621 BSBS38_03622 BSBS38_03622 BSBS38_03622 3381271 3385140 - uncharacterized protein gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03622 BSBS38_03623 BSBS38_03623 BSBS38_03623 3385341 3385700 - putative membrane protein YvlD gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03623 BSBS38_03624 BSBS38_03624 BSBS38_03624 3385702 3385899 - putative membrane protein YvlC gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03624 BSBS38_03625 BSBS38_03625 BSBS38_03625 3385904 3387001 - uncharacterized protein gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03625 BSBS38_03626 BSBS38_03626 BSBS38_03626 3387026 3387352 - uncharacterized protein gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03626 BSBS38_03627 BSBS38_03627 BSBS38_03627 3387570 3387800 + uncharacterized protein gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03627 BSBS38_03628 BSBS38_03628 BSBS38_03628 3387999 3388913 - Flagellin Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Belongs to the bacterial flagellin family gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03628 BSBS38_03629 BSBS38_03629 BSBS38_03629 3389251 3392124 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03629 BSBS38_03630 BSBS38_03630 BSBS38_03630 3392132 3394117 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site%2C the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix%2C facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found%2C the DNA wraps around the other UvrB subunit that will check the other stand for damage%3B Belongs to the UvrB family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 UVR domain gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03630 BSBS38_03631 BSBS38_03631 BSBS38_03631 3394303 3394533 - Protein CsbA gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03631 BSBS38_03632 BSBS38_03632 ppsA ppsA 3394981 3395799 + Pyruvate%2C water dikinase Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU35190 pyruvate%2C water dikinase gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03632 BSBS38_03633 BSBS38_03633 BSBS38_03633 3395898 3397475 + Pyruvate%2C water dikinase Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU35190 pyruvate%2C water dikinase gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03633 BSBS38_03634 BSBS38_03634 BSBS38_03634 3397551 3398120 + putative HTH-type transcriptional regulator YvkB Contains 1 HTH tetR-type DNA-binding domain gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03634 BSBS38_03635 BSBS38_03635 BSBS38_03635 3398168 3399484 + putative MFS-type transporter YvkA Belongs to the major facilitator superfamily. TCR/Tet family gene gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03635 BSBS38_03636 BSBS38_03636 BSBS38_03636 3399532 3400725 - Cell division topological determinant MinJ The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division%2C thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD%3B Belongs to the MinJ family%3B Contains 1 PDZ (DHR) domain gene gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03636 BSBS38_03637 BSBS38_03637 BSBS38_03637 3400804 3401232 - Swarming motility protein SwrAA Required for swarm cell differentiation. Plays a crucial role in regulating the degree of cell flagellation gene gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03637 BSBS38_03638 BSBS38_03638 BSBS38_03638 3401541 3402983 - C-terminal processing peptidase Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro-sigma-K during sporulation. The signaling serine protease CtpB triggers pro-sigma-K processing by cleaving the pre-processed regulatory protein SpoIVFA and is necessary for the proper timing of sigma-K activation%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bsus:Q433_19295 carboxyl-terminal processing protease gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03638 BSBS38_03639 BSBS38_03639 BSBS38_03639 3403123 3404022 - Cell division protein FtsX Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC-4 integral membrane protein family. FtsX subfamily gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03639 BSBS38_03640 BSBS38_03640 BSBS38_03640 3404006 3404692 - Cell division ATP-binding protein FtsE Part of the ABC transporter FtsEX involved in sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03640 BSBS38_03641 BSBS38_03641 BSBS38_03641 3404926 3405264 - Cytochrome c-551 Electron carrier protein%3B Contains 1 cytochrome c domain gene gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03641 BSBS38_03642 BSBS38_03642 BSBS38_03642 3405313 3406158 - UPF0750 membrane protein YvjA Belongs to the UPF0750 family gene gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03642 BSBS38_03643 BSBS38_03643 BSBS38_03643 3406323 3407306 - Peptide chain release factor Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03643 BSBS38_03644 BSBS38_03644 BSBS38_03644 3407494 3410019 - Protein translocase subunit SecA Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane%2C serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane%3B Belongs to the SecA family gene gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03644 BSBS38_03645 BSBS38_03645 BSBS38_03645 3410187 3410756 - uncharacterized protein Belongs to the ribosomal protein S30Ae family gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03645 BSBS38_03646 BSBS38_03646 BSBS38_03646 3410947 3411324 - uncharacterized protein gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03646 BSBS38_03647 BSBS38_03647 BSBS38_03647 3411334 3411675 - Flagellar protein FliT May act as an export chaperone for the filament capping protein FliD. Belongs to the bacillales FliT family gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03647 BSBS38_03648 BSBS38_03648 BSBS38_03648 3411672 3412073 - Flagellar protein FliS Belongs to the FliS family gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03648 BSBS38_03649 BSBS38_03649 BSBS38_03649 3412095 3413591 - Flagellar hook-associated protein Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure%2C which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity)%3B Belongs to the FliD family gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03649 BSBS38_03650 BSBS38_03650 BSBS38_03650 3413609 3413938 - uncharacterized protein gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03650 BSBS38_03651 BSBS38_03651 BSBS38_03651 3414172 3414993 - Flagellin Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Belongs to the bacterial flagellin family gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03651 BSBS38_03652 BSBS38_03652 BSBS38_03652 3415137 3415361 - Carbon storage regulator like protein Could accelerate the degradation of some genes transcripts potentially through selective RNA binding%3B Belongs to the CsrA family gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03652 BSBS38_03653 BSBS38_03653 BSBS38_03653 3415355 3415786 - Flagellar assembly factor FliW Binds to the C-terminal region of flagellin%2C which is implicated in polymerization%2C and participates in the assembly of the flagellum%3B Belongs to the FliW family gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03653 BSBS38_03654 BSBS38_03654 BSBS38_03654 3415807 3416382 - uncharacterized protein gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03654 BSBS38_03655 BSBS38_03655 BSBS38_03655 3416428 3417324 - Flagellar hook-associated protein Belongs to the bacterial flagellin family gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03655 BSBS38_03656 BSBS38_03656 BSBS38_03656 3417335 3418858 - Flagellar hook-associated protein Belongs to the flagella basal body rod proteins family gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03656 BSBS38_03657 BSBS38_03657 BSBS38_03657 3418877 3419359 - uncharacterized protein gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03657 BSBS38_03658 BSBS38_03658 BSBS38_03658 3419375 3419641 - Negative regulator of flagellin synthesis Allows the coupling of early and late flagellar synthesis through the repression of RNA polymerase sigma-D factor- dependent transcription. Belongs to the FlgM family gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03658 BSBS38_03659 BSBS38_03659 BSBS38_03659 3419722 3420141 - uncharacterized protein May be involved in the assembly%2C structure%2C or function of the flagellum. May polymerize to form a filamentous structure that is part of the flagellum. To S. typhimurium FliF gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03659 BSBS38_03660 BSBS38_03660 BSBS38_03660 3420214 3420936 - ComF operon protein Involved in transformation (competence for DNA uptake). Belongs to the ComF/GntX family%3B overlaps another CDS with the same product name gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03660 BSBS38_03661 BSBS38_03661 BSBS38_03661 3420900 3421196 - ComF operon protein overlaps another CDS with the same product name gene gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03661 BSBS38_03662 BSBS38_03662 BSBS38_03662 3421256 3422647 - ComF operon protein Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel. Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03662 BSBS38_03663 BSBS38_03663 BSBS38_03663 3422754 3423599 - Protein DegV Binds long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03663 BSBS38_03664 BSBS38_03664 BSBS38_03664 3423697 3424386 - Transcriptional regulatory protein DegU Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation%2C biofilm formation%2C and competence for DNA uptake. Positively or negatively regulates expression of many different genes. The phosphorylated form is required for synthesis of degradative enzymes%2C flagellum formation and biofilm formation. The unphosphorylated form is required for expression of genetic competence%2C via induction of comK%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03664 BSBS38_03665 BSBS38_03665 degS degS 3424469 3425626 - Histidine kinase Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation and biofilm formation. Acts as both a protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to DegU%2C and a protein phosphatase that dephosphorylates phospho- DegU%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU35500 two-component system%2C NarL family%2C sensor histidine kinase DegS gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03665 BSBS38_03666 BSBS38_03666 BSBS38_03666 3425843 3426496 + Xaa-Pro dipeptidase Belongs to the IMPACT family%3B KEGG: sph:MGAS10270_Spy1444 Xaa-Pro dipeptidase gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03666 BSBS38_03667 BSBS38_03667 BSBS38_03667 3426567 3427487 + Putative transcriptional regulator YvhJ Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03667 BSBS38_03668 BSBS38_03668 BSBS38_03668 3428094 3428549 + hypothetical protein gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03668 BSBS38_03669 BSBS38_03669 BSBS38_03669 3428598 3429053 + hypothetical protein gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03669 BSBS38_03670 BSBS38_03670 BSBS38_03670 3429104 3429556 + hypothetical protein gene gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03670 BSBS38_03671 BSBS38_03671 BSBS38_03671 3429632 3430411 + hypothetical protein gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03671 BSBS38_03672 BSBS38_03672 BSBS38_03672 3430398 3431189 + hypothetical protein gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03672 BSBS38_03673 BSBS38_03673 BSBS38_03673 3431205 3432014 + hypothetical protein gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03673 BSBS38_03674 BSBS38_03674 BSBS38_03674 3432034 3432693 + Sulfate/thiosulfate import ATP-binding protein CysA Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3. A. 1. 6) family%3B Contains 1 ABC transporter domain gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03674 BSBS38_03675 BSBS38_03675 BSBS38_03675 3432721 3433236 + hypothetical protein gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03675 BSBS38_03676 BSBS38_03676 wecA wecA 3433309 3434385 - UDP-N-acetylglucosamine--undecaprenyl-phosphateN-acetylglucosaminephosphotransferase Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B. subtili%3B may also be involved in teichuronic acid biosynthesis (Probable)%3B Belongs to the glycosyltransferase 4 family%3B KEGG: bsu:BSU35530 UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03676 BSBS38_03677 BSBS38_03677 tuaH tuaH 3434531 3435730 - Putative teichuronic acid biosynthesis glycosyltransferase TuaH Belongs to the glycosyltransferase group 1 family%3B KEGG: bsy:I653_17305 teichuronic acid biosynthesis glycosyltransferase TuaH%3B Glycosyltransferases gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03677 BSBS38_03678 BSBS38_03678 tuaG tuaG 3435753 3436511 - putative glycosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: bso:BSNT_05412 teichuronic acid biosynthesis glycosyltransferase TuaG%3B Glycosyltransferases gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03678 BSBS38_03679 BSBS38_03679 BSBS38_03679 3436541 3437215 - Teichuronic acid biosynthesis protein TuaF gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03679 BSBS38_03680 BSBS38_03680 BSBS38_03680 3437257 3438711 - Teichuronic acid biosynthesis protein TuaE gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03680 BSBS38_03681 BSBS38_03681 BSBS38_03681 3439447 3439641 + hypothetical protein gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03681 BSBS38_03682 BSBS38_03682 BSBS38_03682 3439587 3440921 - UDP-glucose 6-dehydrogenase Catalyzes the conversion of UDP-glucose into UDP- glucuronate%2C one of the precursors of teichuronic acid. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: bso:BSNT_05418 UDPglucose 6-dehydrogenase gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03682 BSBS38_03683 BSBS38_03683 tuaC tuaC 3441115 3442290 - Putative teichuronic acid biosynthesis glycosyltransferase TuaC Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bsu:BSU35590 teichuronic acid biosynthesis glycosyltransferase TuaC%3B Glycosyltransferases gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03683 BSBS38_03684 BSBS38_03684 BSBS38_03684 3442313 3443752 - Teichuronic acid biosynthesis protein TuaB Might be involved in the translocation of teichuronic acid repeating units from the inner to the outer surface of the membrane. Belongs to the polysaccharide synthase family gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03684 BSBS38_03685 BSBS38_03685 BSBS38_03685 3443776 3444435 - Putative undecaprenyl-phosphate N-acetylgalactosaminyl 1-phosphate transferase Might mediate the very first reaction in teichuronic synthesis%2C i. e. the formation of lipid-linked N-acetylglucosamine. Belongs to the bacterial sugar transferase family gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03685 BSBS38_03686 BSBS38_03686 BSBS38_03686 3444667 3446154 - N-acetylmuramoyl-L-alanine amidase Autolysins are cell wall hydrolases involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teichoic acid-endowed peptidoglycan. LytC is required for efficient swarming motility but not at the level of cell separation or flagellum biosynthesis. Rather%2C LytC appears to be important for proper flagellar function%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bli:BL03348 N-acetylmuramoyl-L-alanine amidase gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03686 BSBS38_03687 BSBS38_03687 BSBS38_03687 3446239 3448383 - N-acetylmuramoyl-L-alanine amidase KEGG: bpu:BPUM_3214 N-acetylmuramoyl-L-alanine amidase gene gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03687 BSBS38_03688 BSBS38_03688 BSBS38_03688 3448412 3448732 - Membrane-bound protein LytA gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03688 BSBS38_03689 BSBS38_03689 BSBS38_03689 3449645 3449848 + Transcriptional regulator LytR Attenuator role for operon expression%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03689 BSBS38_03690 BSBS38_03690 wecB wecB 3449875 3451017 - UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine%2C a precursor of the teichoic acid linkage unit%3B Belongs to the UDP-N-acetylglucosamine 2-epimerase family%3B KEGG: cfu:CFU_3660 UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03690 BSBS38_03691 BSBS38_03691 BSBS38_03691 3451347 3452225 + UTP--glucose-1-phosphate uridylyltransferase Belongs to the UDPGP type 2 family%3B KEGG: pmr:PMI1490 UTP--glucose-1-phosphate uridylyltransferase gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03691 BSBS38_03692 BSBS38_03692 BSBS38_03692 3453240 3453362 - hypothetical protein gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03692 BSBS38_03693 BSBS38_03693 tagH tagH 3453456 3454373 - Teichoic-acid-transporting ATPase Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3. A. 1. 104. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU35700 teichoic acid transport system ATP-binding protein gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03693 BSBS38_03694 BSBS38_03694 BSBS38_03694 3454394 3455221 - Teichoic acid translocation permease protein TagG Part of the ABC transporter complex TagGH (TC 3. A. 1. 34. 1) involved in exporting the two types of intracellularly synthesized teichoic acids. Probably responsible for the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03694 BSBS38_03695 BSBS38_03695 BSBS38_03695 3455867 3456715 + hypothetical protein gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03695 BSBS38_03696 BSBS38_03696 BSBS38_03696 3456921 3459497 - CDP-glycerol glycerophosphotransferase Catalyzes the addition of a second single glycerol-P residue to the prenolpyrophosphate-linked disaccharide%2C to complete the linkage unit%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bso:BSNT_05451 CDP-glycerol glycerophosphotransferase gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03696 BSBS38_03697 BSBS38_03697 BSBS38_03697 3459809 3461944 - CDP-glycerol glycerophosphotransferase Is responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glycerol to the disaccharide linkage unit. Synthesizes polymers of approximately 35 glycerol phosphate units in length%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bso:BSNT_05452 CDP-glycerol glycerophosphotransferase gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03697 BSBS38_03698 BSBS38_03698 tagD tagD 3462088 3462483 - Glycerol-3-phosphate cytidylyltransferase Provides activated glycerol phosphate for teichoic acid synthesis%2C via incorporation into both the linkage unit and the teichoic acid polymer by TagB and TagF. Belongs to the cytidylyltransferase family%3B KEGG: ecc:c3696 glycerol-3-phosphate cytidylyltransferase gene gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03698 BSBS38_03699 BSBS38_03699 tagA tagA 3462840 3463622 + N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol%2C a key lipid intermediate in the de novo synthesis of teichoic acid%3B Belongs to the glycosyltransferase 26 family%3B KEGG: bso:BSNT_05454 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03699 BSBS38_03700 BSBS38_03700 tarL tarL 3463642 3464805 + CDP-ribitol ribitolphosphotransferase Catalyzes the addition of a first single glycerol-P residue to the prenolpyrophosphate-linked disaccharide%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bsl:A7A1_1141 CDP-ribitol ribitolphosphotransferase gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03700 BSBS38_03701 BSBS38_03701 BSBS38_03701 3464834 3467476 - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Cell wall hydrolase not involved in cell autolysis%2C competence%2C sporulation or germination. It hydrolyzes the beta-1%2C4 glycan bond between the N-acetylglucosaminyl and the N- acetylmuramoyl residues in the glycan chain%3B Belongs to the glycosyl hydrolase 73 family%3B Contains 3 SPOR domains%3B KEGG: bsu:BSU35780 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03701 BSBS38_03702 BSBS38_03702 BSBS38_03702 3467606 3468556 - Mannose-6-phosphate isomerase Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bsu:BSU35790 mannose-6-phosphate isomerase gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03702 BSBS38_03703 BSBS38_03703 BSBS38_03703 3468826 3469353 + Spore germination protein Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors respectively). Belongs to the GerABKA family gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03703 BSBS38_03704 BSBS38_03704 BSBS38_03704 3469401 3470276 + Spore germination protein Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors respectively). Belongs to the GerABKA family gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03704 BSBS38_03705 BSBS38_03705 BSBS38_03705 3470276 3471388 + Spore germination protein B2 Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Could be an amino acid transporter. Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively). Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03705 BSBS38_03706 BSBS38_03706 BSBS38_03706 3471385 3472509 + Spore germination protein B3 Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors respectively). Belongs to the GerABKC lipoprotein family gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03706 BSBS38_03707 BSBS38_03707 BSBS38_03707 3472546 3473430 - putative metabolite transport protein CsbC Could serve either a nutritional or an osmotic protection function. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03707 BSBS38_03708 BSBS38_03708 BSBS38_03708 3473431 3473919 - Putative metabolite transport protein YwtG Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03708 BSBS38_03709 BSBS38_03709 BSBS38_03709 3474250 3475236 + Putative transcriptional regulator YwtF Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03709 BSBS38_03710 BSBS38_03710 BSBS38_03710 3475394 3476254 + Putative phosphatase YwtE Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03710 BSBS38_03711 BSBS38_03711 BSBS38_03711 3476288 3477649 - Gamma-DL-glutamyl hydrolase Cleaves%2C in an endo-type manner%2C the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA). Belongs to the peptidase C40 family gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03711 BSBS38_03712 BSBS38_03712 BSBS38_03712 3477670 3477837 - uncharacterized protein gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03712 BSBS38_03713 BSBS38_03713 BSBS38_03713 3477852 3478994 - PGA biosynthesis protein CapA Seems to be required for maximum PGA (gamma-polyglutamic acid) production. Belongs to the CapA family gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03713 BSBS38_03714 BSBS38_03714 BSBS38_03714 3479013 3479462 - Capsule biosynthesis protein CapC gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03714 BSBS38_03715 BSBS38_03715 BSBS38_03715 3479477 3480658 - PGA synthase CapB Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03715 BSBS38_03716 BSBS38_03716 BSBS38_03716 3481440 3482429 + Sucrose operon repressor Repressor for the csc operon. Binds D-fructose as an inducer (By similarity)%3B Contains 1 HTH lacI-type DNA-binding domain gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03716 BSBS38_03717 BSBS38_03717 rbsK rbsK 3482422 3483303 + Ribokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU35920 ribokinase gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03717 BSBS38_03718 BSBS38_03718 rbsD rbsD 3483300 3483695 + D-ribose pyranase Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose%3B Belongs to the RbsD / FucU family. RbsD subfamily%3B KEGG: cvi:CV_3019 D-ribose pyranase gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03718 BSBS38_03719 BSBS38_03719 cysA cysA 3483711 3485192 + Sulfate-transporting ATPase Belongs to the ABC transporter superfamily. Ycf16 family%3B Contains 1 ABC transporter domain%3B KEGG: eco:b2422 sulfate transport system ATP-binding protein gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03719 BSBS38_03720 BSBS38_03720 BSBS38_03720 3485194 3486162 + Ribose transport system permease protein RbsC Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03720 BSBS38_03721 BSBS38_03721 BSBS38_03721 3486298 3487092 + D-ribose-binding protein Involved in the high-affinity D-ribose membrane transport system. Belongs to the bacterial solute-binding protein 2 family gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03721 BSBS38_03722 BSBS38_03722 BSBS38_03722 3487174 3487710 + Cell wall-binding protein YwsB gene gene3721 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03722 BSBS38_03723 BSBS38_03723 BSBS38_03723 3487866 3488162 + uncharacterized protein gene gene3722 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03723 BSBS38_03724 BSBS38_03724 BSBS38_03724 3488202 3488729 - General stress protein Belongs to the NAD(P)H dehydrogenase (quinone) family gene gene3723 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03724 BSBS38_03725 BSBS38_03725 alsD alsD 3488827 3489594 - Acetolactate decarboxylase Converts acetolactate into acetoin%2C which can be excreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage. Belongs to the alpha-acetolactate decarboxylase family%3B KEGG: bsu:BSU36000 acetolactate decarboxylase gene gene3724 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03725 BSBS38_03726 BSBS38_03726 BSBS38_03726 3489656 3491371 - Acetolactate synthase Belongs to the TPP enzyme family%3B KEGG: bsl:A7A1_1116 acetolactate synthase I/II/III large subunit gene gene3725 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03726 BSBS38_03727 BSBS38_03727 BSBS38_03727 3491526 3492434 + HTH-type transcriptional regulator AlsR Regulates the expression of the alsSD operon for acetoin biosynthesis. Contains 1 HTH lysR-type DNA-binding domain gene gene3726 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03727 BSBS38_03728 BSBS38_03728 BSBS38_03728 3492759 3493973 + Putative arsenical pump membrane protein Belongs to the ArsB family gene gene3727 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03728 BSBS38_03729 BSBS38_03729 BSBS38_03729 3494030 3494707 - uncharacterized protein gene gene3728 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03729 BSBS38_03730 BSBS38_03730 BSBS38_03730 3494767 3495894 - Spore coat protein gene gene3729 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03730 BSBS38_03731 BSBS38_03731 BSBS38_03731 3496023 3497111 - Inner spore coat protein Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides on the spore surface%3B Belongs to the CotH family gene gene3730 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03731 BSBS38_03732 BSBS38_03732 BSBS38_03732 3497253 3497837 + Spore coat protein gene gene3731 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03732 BSBS38_03733 BSBS38_03733 BSBS38_03733 3498011 3498628 + uncharacterized protein Belongs to the flavoredoxin family gene gene3732 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03733 BSBS38_03734 BSBS38_03734 BSBS38_03734 3498805 3499140 + uncharacterized protein gene gene3733 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03734 BSBS38_03735 BSBS38_03735 BSBS38_03735 3499145 3500722 - Gamma-glutamyltransferase Belongs to the gamma-glutamyltransferase family%3B KEGG: bsu:BSU36100 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene3734 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03735 BSBS38_03736 BSBS38_03736 BSBS38_03736 3500936 3501412 + putative HTH-type transcriptional regulator YwrC Contains 1 HTH asnC-type DNA-binding domain gene gene3735 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03736 BSBS38_03737 BSBS38_03737 BSBS38_03737 3501426 3502019 + putative transporter YwrB Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene3736 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03737 BSBS38_03738 BSBS38_03738 BSBS38_03738 3502016 3502552 + putative transporter YwrA Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene3737 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03738 BSBS38_03739 BSBS38_03739 BSBS38_03739 3502580 3502801 - uncharacterized protein gene gene3738 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03739 BSBS38_03740 BSBS38_03740 BSBS38_03740 3503059 3503343 - Putative NAD(P)H-dependent FMN-containing oxidoreductase YwqN Putative NADPH-dependent oxidoreductase%3B Belongs to the SsuE family gene gene3739 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03740 BSBS38_03741 BSBS38_03741 BSBS38_03741 3503466 3504347 + putative HTH-type transcriptional regulator YwqM Contains 1 HTH lysR-type DNA-binding domain gene gene3740 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03741 BSBS38_03742 BSBS38_03742 BSBS38_03742 3504340 3505146 - Deoxyribonuclease V DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B Belongs to the endonuclease V family%3B KEGG: bsl:A7A1_1100 deoxyribonuclease V gene gene3741 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03742 BSBS38_03743 BSBS38_03743 BSBS38_03743 3505267 3505620 - hypothetical protein gene gene3742 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03743 BSBS38_03744 BSBS38_03744 BSBS38_03744 3505633 3505977 - hypothetical protein gene gene3743 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03744 BSBS38_03745 BSBS38_03745 BSBS38_03745 3506016 3506600 - Ribonuclease YqcG Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 379-531) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YqcF%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene3744 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03745 BSBS38_03746 BSBS38_03746 BSBS38_03746 3506753 3506962 - hypothetical protein gene gene3745 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03746 BSBS38_03747 BSBS38_03747 BSBS38_03747 3506976 3507494 - hypothetical protein gene gene3746 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03747 BSBS38_03748 BSBS38_03748 BSBS38_03748 3507502 3509292 - Putative ribonuclease YwqJ Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YwqK%2C but not by antitoxins specific to other toxins with the LXG domain (By similarity)%3B Contains 1 LXG domain gene gene3747 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03748 BSBS38_03749 BSBS38_03749 BSBS38_03749 3509311 3509583 - uncharacterized protein overlaps another CDS with the same product name gene gene3748 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03749 BSBS38_03750 BSBS38_03750 BSBS38_03750 3509580 3510002 - uncharacterized protein overlaps another CDS with the same product name gene gene3749 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03750 BSBS38_03751 BSBS38_03751 BSBS38_03751 3510480 3510941 - uncharacterized protein gene gene3750 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03751 BSBS38_03752 BSBS38_03752 BSBS38_03752 3510977 3511264 - uncharacterized protein gene gene3751 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03752 BSBS38_03753 BSBS38_03753 BSBS38_03753 3511476 3512798 - UDP-glucose 6-dehydrogenase Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins. Involved in the biosynthesis of the hexuronic acids found at both positions 2 and 3 of the pentasaccharide%3B Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: fau:Fraau_2507 UDPglucose 6-dehydrogenase gene gene3752 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03753 BSBS38_03754 BSBS38_03754 BSBS38_03754 3512993 3513757 - Protein-tyrosine-phosphatase Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the CpsB/CapC family%3B KEGG: pfv:Psefu_1694 protein-tyrosine phosphatase gene gene3753 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03754 BSBS38_03755 BSBS38_03755 BSBS38_03755 3513806 3514492 - Tyrosine-protein kinase YwqD May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases%2C YwqF and TuaD%2C as well as the DNA-binding proteins Ssb and SsbB%3B Belongs to the CpsD/CapB family%3B KEGG: eco:b2060 tyrosine-protein kinase Etk/Wzc%3B Protein-tyrosine kinases gene gene3754 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03755 BSBS38_03756 BSBS38_03756 BSBS38_03756 3514512 3515258 - putative capsular polysaccharide biosynthesis protein YwqC Required for YwqD kinase activity. May bring YwqD and its substrates into contact. Probably involved in the regulation of capsular polysaccharide biosynthesis%3B Belongs to the CpsC/CapA family gene gene3755 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03756 BSBS38_03757 BSBS38_03757 BSBS38_03757 3515492 3515635 - uncharacterized protein gene gene3756 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03757 BSBS38_03758 BSBS38_03758 BSBS38_03758 3515839 3517449 + uncharacterized protein Contains 1 SWIM-type zinc finger gene gene3757 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03758 BSBS38_03759 BSBS38_03759 swr1 swr1 3517436 3520204 + DNA helicase Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: cot:CORT_0C05660 helicase SWR1 gene gene3758 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03759 BSBS38_03760 BSBS38_03760 BSBS38_03760 3520330 3521187 - Putative phosphatase YcsE Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3759 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03760 BSBS38_03761 BSBS38_03761 BSBS38_03761 3521193 3521969 - HTH-type transcriptional repressor GlcR Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars%3B Contains 1 HTH deoR-type DNA-binding domain gene gene3760 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03761 BSBS38_03762 BSBS38_03762 BSBS38_03762 3522193 3522534 - Single-stranded DNA-binding protein Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene3761 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03762 BSBS38_03763 BSBS38_03763 BSBS38_03763 3522787 3522993 - uncharacterized protein gene gene3762 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03763 BSBS38_03764 BSBS38_03764 BSBS38_03764 3523168 3523578 + uncharacterized protein gene gene3763 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03764 BSBS38_03765 BSBS38_03765 BSBS38_03765 3523718 3524026 - Sortase A Belongs to the peptidase C60 family%3B KEGG: bsr:I33_3766 sortase A gene gene3764 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03765 BSBS38_03766 BSBS38_03766 BSBS38_03766 3524340 3525206 + Histidine kinase Contains 1 response regulatory domain%3B KEGG: bth:BT_1058 two-component system%2C unclassified family%2C sensor histidine kinase and response regulator gene gene3765 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03766 BSBS38_03767 BSBS38_03767 BSBS38_03767 3525254 3525649 - Large-conductance mechanosensitive channel Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell%3B Belongs to the MscL family gene gene3766 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03767 BSBS38_03768 BSBS38_03768 BSBS38_03768 3525722 3526192 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs%3B Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bsl:A7A1_1078 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene3767 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03768 BSBS38_03769 BSBS38_03769 rapD rapD 3526339 3527403 + Response regulator aspartate phosphatase D Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU36380 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene3768 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03769 BSBS38_03770 BSBS38_03770 BSBS38_03770 3527426 3528235 - Flagellar hook-basal body complex protein FlhP Belongs to the flagella basal body rod proteins family gene gene3769 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03770 BSBS38_03771 BSBS38_03771 BSBS38_03771 3528268 3529080 - Flagellar hook-basal body complex protein FlhO Not required for motility. Belongs to the flagella basal body rod proteins family gene gene3770 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03771 BSBS38_03772 BSBS38_03772 BSBS38_03772 3529243 3530244 - MreB-like protein Belongs to the FtsA/MreB family gene gene3771 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03772 BSBS38_03773 BSBS38_03773 BSBS38_03773 3530410 3530691 - Stage III sporulation protein This protein regulates the transcription of sigK%2C which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). Contains 1 HTH deoR-type DNA-binding domain gene gene3772 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03773 BSBS38_03774 BSBS38_03774 BSBS38_03774 3531041 3531454 + putative HTH-type transcriptional regulator YwoH Contains 1 HTH marR-type DNA-binding domain gene gene3773 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03774 BSBS38_03775 BSBS38_03775 BSBS38_03775 3531476 3532666 + putative MFS-type transporter YwoG Belongs to the major facilitator superfamily gene gene3774 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03775 BSBS38_03776 BSBS38_03776 BSBS38_03776 3532750 3534156 - uncharacterized protein Contains 8 PbH1 repeats gene gene3775 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03776 BSBS38_03777 BSBS38_03777 BSBS38_03777 3534262 3535734 - putative allantoin permease Transport of allantoin%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene3776 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03777 BSBS38_03778 BSBS38_03778 BSBS38_03778 3535915 3537276 - putative MFS-type transporter YwoD Belongs to the major facilitator superfamily gene gene3777 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03778 BSBS38_03779 BSBS38_03779 pncA pncA 3537273 3537842 - putative isochorismatase family protein YwoC Belongs to the isochorismatase family%3B KEGG: kpf:IX53_06260 nicotinamidase/pyrazinamidase%3B Nicotinamidase gene gene3778 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03779 BSBS38_03780 BSBS38_03780 BSBS38_03780 3538026 3538487 - uncharacterized protein gene gene3779 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03780 BSBS38_03781 BSBS38_03781 BSBS38_03781 3538771 3539985 + Ammonium transporter NrgA Functions as an ammonium and methylammonium transporter in the absence of glutamine. Required for ammonium utilization at low concentrations or at low pH values%2C when ammonium is the single nitrogen source. Required for binding of NrgB to the membrane%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene3780 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03781 BSBS38_03782 BSBS38_03782 BSBS38_03782 3539997 3540347 + Nitrogen regulatory PII-like protein Required for full induction of the nrgAB operon under conditions of ammonium limitation%3B Belongs to the P(II) protein family gene gene3781 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03782 BSBS38_03783 BSBS38_03783 BSBS38_03783 3540530 3541111 + Undecaprenyl-diphosphate phosphatase Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the BcrC/YbjG family%3B KEGG: bsu:BSU36530 undecaprenyl-diphosphatase gene gene3782 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03783 BSBS38_03784 BSBS38_03784 BSBS38_03784 3541152 3541574 - putative membrane protein YwnJ gene gene3783 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03784 BSBS38_03785 BSBS38_03785 BSBS38_03785 3541685 3542557 - Stage II sporulation protein Involved in forespore engulfment and required for anchoring membrane proteins on the forespore side of the septal membrane. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene3784 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03785 BSBS38_03786 BSBS38_03786 BSBS38_03786 3542692 3543189 + Phosphinothricin acetyltransferase This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Inactivates PTT by transfer of an acetyl group (By similarity)%3B Belongs to the acetyltransferase family. PAT/BAR subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsr:I33_3791 phosphinothricin acetyltransferase gene gene3785 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03786 BSBS38_03787 BSBS38_03787 BSBS38_03787 3543186 3543704 + uncharacterized protein gene gene3786 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03787 BSBS38_03788 BSBS38_03788 legI legI 3543911 3545689 + N%2CN'-diacetyllegionaminate synthase Catalyzes the fifth step in the biosynthesis of pseudaminic acid%2C a sialic-acid-like sugar that is used to modify flagellin. Catalyzes the condensation of phosphoenolpyruvate with 2%2C4-diacetamido-2%2C4%2C6-trideoxy-beta-l-altropyranose%2C forming pseudaminic acid%3B Belongs to the pseudaminic acid synthase family%3B Contains 1 AFP-like domain%3B KEGG: bst:GYO_4022 N%2CN'-diacetyllegionaminate synthase gene gene3787 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03788 BSBS38_03789 BSBS38_03789 BSBS38_03789 3545771 3546208 - uncharacterized protein gene gene3788 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03789 BSBS38_03790 BSBS38_03790 BSBS38_03790 3546409 3547899 + Major cardiolipin synthase ClsA Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bsut:BSUB_03893 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3789 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03790 BSBS38_03791 BSBS38_03791 BSBS38_03791 3547923 3548696 - HTH-type transcriptional activator mta Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself%2C ydfK and ymfE%3B Contains 1 HTH merR-type DNA-binding domain gene gene3790 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03791 BSBS38_03792 BSBS38_03792 BSBS38_03792 3548841 3549224 + uncharacterized protein gene gene3791 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03792 BSBS38_03793 BSBS38_03793 BSBS38_03793 3549259 3549900 - uncharacterized protein gene gene3792 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03793 BSBS38_03794 BSBS38_03794 BSBS38_03794 3549968 3550369 - Putative HTH-type transcriptional regulator YwnA Contains 1 HTH rrf2-type DNA-binding domain gene gene3793 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03794 BSBS38_03795 BSBS38_03795 ureC ureC 3550504 3552213 - Urease Belongs to the urease family%3B Contains 1 urease domain%3B KEGG: bpn:BPEN_542 urease subunit alpha%3B overlaps another CDS with the same product name gene gene3794 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03795 BSBS38_03796 BSBS38_03796 ureB ureB 3552210 3552584 - Urease Belongs to the urease beta subunit family%3B KEGG: bsu:BSU36650 urease subunit beta%3B overlaps another CDS with the same product name gene gene3795 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03796 BSBS38_03797 BSBS38_03797 BSBS38_03797 3552581 3552898 - Urease In the N-terminal sectio%3B belongs to the urease gamma subunit family%3B In the C-terminal sectio%3B belongs to the urease beta subunit family%3B KEGG: heu:HPPN135_05405 urease subunit gamma/beta%3B overlaps another CDS with the same product name gene gene3796 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03797 BSBS38_03798 BSBS38_03798 BSBS38_03798 3553943 3554131 - Stress response protein CsbD Belongs to the UPF0337 (CsbD) family gene gene3797 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03798 BSBS38_03799 BSBS38_03799 BSBS38_03799 3554204 3554848 - putative membrane protein YwmF gene gene3798 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03799 BSBS38_03800 BSBS38_03800 rapB rapB 3554838 3555971 - Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F. Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU36690 response regulator aspartate phosphatase B%3B Acting on ester bonds gene gene3799 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03800 BSBS38_03801 BSBS38_03801 moaA moaA 3556163 3557188 - Cyclic pyranopterin phosphate synthase Catalyzes%2C together with MoaC%2C the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the radical SAM superfamily. MoaA family%3B KEGG: bsu:BSU36700 cyclic pyranopterin phosphate synthase gene gene3800 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03801 BSBS38_03802 BSBS38_03802 BSBS38_03802 3557204 3557992 - Protein FdhD like protein Necessary for formate dehydrogenase activity. Belongs to the FdhD family gene gene3801 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03802 BSBS38_03803 BSBS38_03803 BSBS38_03803 3558225 3558386 - uncharacterized protein gene gene3802 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03803 BSBS38_03804 BSBS38_03804 BSBS38_03804 3558481 3559155 - uncharacterized protein Contains 1 VWFA domain%3B To B. subtilis YwmC gene gene3803 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03804 BSBS38_03805 BSBS38_03805 BSBS38_03805 3559479 3560162 - uncharacterized protein Contains 1 VWFA domain%3B To B. subtilis YwmD gene gene3804 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03805 BSBS38_03806 BSBS38_03806 BSBS38_03806 3560548 3561579 - Stage II sporulation protein D gene gene3805 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03806 BSBS38_03807 BSBS38_03807 murA murA 3561775 3563085 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: spoi:IMCC21906_01188 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene3806 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03807 BSBS38_03808 BSBS38_03808 BSBS38_03808 3563119 3563859 - uncharacterized protein gene gene3807 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03808 BSBS38_03809 BSBS38_03809 BSBS38_03809 3563994 3564224 - putative membrane protein YwzB gene gene3808 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03809 BSBS38_03810 BSBS38_03810 BSBS38_03810 3564394 3564867 + uncharacterized protein gene gene3809 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03810 BSBS38_03811 BSBS38_03811 BSBS38_03811 3564901 3565299 - ATP synthase epsilon chain Produces ATP from ADP in the presence of a proton gradient across the membrane%3B Belongs to the ATPase epsilon chain family gene gene3810 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03811 BSBS38_03812 BSBS38_03812 atpD atpD 3565323 3566744 - H(+)-transporting two-sector ATPase Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: bsu:BSU36810 F-type H+-transporting ATPase subunit beta gene gene3811 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03812 BSBS38_03813 BSBS38_03813 BSBS38_03813 3566770 3567633 - ATP synthase gamma chain Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex%3B Belongs to the ATPase gamma chain family gene gene3812 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03813 BSBS38_03814 BSBS38_03814 atpA atpA 3567710 3569218 - H(+)-transporting two-sector ATPase Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: hhm:BN341_p0008 F-type H+-transporting ATPase subunit alpha gene gene3813 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03814 BSBS38_03815 BSBS38_03815 BSBS38_03815 3569235 3569780 - ATP synthase subunit delta F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction%3B Belongs to the ATPase delta chain family gene gene3814 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03815 BSBS38_03816 BSBS38_03816 BSBS38_03816 3569777 3570289 - ATP synthase subunit F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Component of the F(0) channel%2C it forms part of the peripheral stalk%2C linking F(1) to F(0)%3B Belongs to the ATPase B chain family gene gene3815 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03816 BSBS38_03817 BSBS38_03817 BSBS38_03817 3570452 3570664 - ATP synthase subunit F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Key component of the F(0) channe%3B it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits%3B Belongs to the ATPase C chain family gene gene3816 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03817 BSBS38_03818 BSBS38_03818 BSBS38_03818 3570710 3571444 - ATP synthase subunit Key component of the proton channe%3B it plays a direct role in the translocation of protons across the membrane%3B Belongs to the ATPase A chain family gene gene3817 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03818 BSBS38_03819 BSBS38_03819 BSBS38_03819 3571452 3571835 - ATP synthase protein A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex. Belongs to the bacterial AtpI family gene gene3818 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03819 BSBS38_03820 BSBS38_03820 uprT uprT 3572259 3572888 - Uracil phosphoribosyltransferase Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate%3B Belongs to the UPRTase family%3B KEGG: bsu:BSU36890 uracil phosphoribosyltransferase gene gene3819 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03820 BSBS38_03821 BSBS38_03821 glyA glyA 3573023 3574270 - Glycine hydroxymethyltransferase Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines%2C thymidylate%2C methionine%2C and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids%2C producing glycine and aldehydes%2C via a retro-aldol mechanism%3B Belongs to the SHMT family%3B KEGG: bsu:BSU36900 glycine hydroxymethyltransferase gene gene3820 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03821 BSBS38_03822 BSBS38_03822 BSBS38_03822 3574477 3575019 - UPF0340 protein YwlG Belongs to the UPF0340 family gene gene3821 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03822 BSBS38_03823 BSBS38_03823 rpiB rpiB 3575032 3575481 - Ribose-5-phosphate isomerase Belongs to the LacAB/RpiB family%3B KEGG: bsu:BSU36920 ribose 5-phosphate isomerase B gene gene3822 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03823 BSBS38_03824 BSBS38_03824 BSBS38_03824 3575638 3576090 - Protein-tyrosine-phosphatase Catalyzes the specific dephosphorylation of phosphoarginine residues in a large number of proteins. Counteracts the protein arginine kinase McsB in vivo. Can dephosphorylate CtsR-%3B thus%2C can restore the DNA-binding ability of the CtsR repressor by reversing the McsB-mediated phosphorylation. Is the only active pArg phosphatase present in B. subtilis. Exhibits almost no activity against pSer%2C pThr%2C or pTyr peptides. Appears to play a role in B. subtilis stress resistance. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: bsu:BSU36930 protein-tyrosine phosphatase gene gene3823 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03824 BSBS38_03825 BSBS38_03825 BSBS38_03825 3576166 3576723 - Putative manganese efflux pump MntP Probably functions as a manganese efflux pump%3B Belongs to the MntP (TC 9. B. 29) family gene gene3824 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03825 BSBS38_03826 BSBS38_03826 tsaC tsaC 3576802 3577842 - L-threonylcarbamoyladenylate synthase Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine%2C HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate%2C with the release of diphosphate. Is also able to catalyze the reverse reaction in vitro%2C i. e. the formation of ATP from TC-AMP and PPi%3B Belongs to the SUA5 family%3B Contains 1 YrdC-like domain%3B KEGG: bsu:BSU36950 L-threonylcarbamoyladenylate synthase gene gene3825 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03826 BSBS38_03827 BSBS38_03827 BSBS38_03827 3577999 3578442 - uncharacterized protein gene gene3826 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03827 BSBS38_03828 BSBS38_03828 BSBS38_03828 3578509 3579183 - Stage II sporulation protein gene gene3827 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03828 BSBS38_03829 BSBS38_03829 BSBS38_03829 3579324 3579701 + UPF0715 membrane protein YwlA Belongs to the UPF0715 family gene gene3828 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03829 BSBS38_03830 BSBS38_03830 BSBS38_03830 3579698 3579985 - uncharacterized protein gene gene3829 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03830 BSBS38_03831 BSBS38_03831 hemK hemK 3580045 3580911 - Peptide chain release factor N(5)-glutamine methyltransferase Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif%3B Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily%3B KEGG: bsu:BSU37000 release factor glutamine methyltransferase gene gene3830 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03831 BSBS38_03832 BSBS38_03832 BSBS38_03832 3580908 3581981 - Peptide chain release factor Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene3831 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03832 BSBS38_03833 BSBS38_03833 BSBS38_03833 3582107 3582493 + uncharacterized protein gene gene3832 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03833 BSBS38_03834 BSBS38_03834 BSBS38_03834 3582615 3583169 + Chromosome-anchoring protein RacA Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells%2C thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome%2C causing condensation of the chromosome and its remodeling into an elongated%2C anchored structure%3B Belongs to the RacA family gene gene3833 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03834 BSBS38_03835 BSBS38_03835 BSBS38_03835 3583202 3584161 - putative transporter YwkB Belongs to the auxin efflux carrier (TC 2. A. 69) family gene gene3834 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03835 BSBS38_03836 BSBS38_03836 BSBS38_03836 3584243 3585940 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bsu:BSU37050 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene3835 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03836 BSBS38_03837 BSBS38_03837 BSBS38_03837 3586230 3586817 - Thymidine kinase Belongs to the thymidine kinase family%3B KEGG: bsu:BSU37060 thymidine kinase gene gene3836 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03837 BSBS38_03838 BSBS38_03838 BSBS38_03838 3586906 3587106 - 50S ribosomal protein L31 Binds the 23S rRNA%3B Belongs to the ribosomal protein L31P family. Type A subfamily gene gene3837 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03838 BSBS38_03839 BSBS38_03839 BSBS38_03839 3587225 3588508 - Transcription termination factor Rho Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA%2C activation of Rho's RNA-dependent ATPase activity%2C and release of the mRNA from the DNA template%3B Belongs to the Rho family gene gene3838 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03839 BSBS38_03840 BSBS38_03840 glpX glpX 3588914 3589879 - Fructose-bisphosphatase Catalyzes the hydrolysis of fructose 1%2C6-bisphosphate (Fru 1%2C6-P2) and sedoheptulose 1%2C7-bisphosphate (Sed 1%2C7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate%2C respectively%3B Belongs to the FBPase class 2 family%3B KEGG: hap:HAPS_0273 fructose-1%2C6-bisphosphatase II gene gene3839 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03840 BSBS38_03841 BSBS38_03841 BSBS38_03841 3589910 3591199 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: bsu:BSU37100 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene3840 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03841 BSBS38_03842 BSBS38_03842 talA talA 3591578 3592216 - Transaldolase Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway%3B Belongs to the transaldolase family. Type 3B subfamily%3B KEGG: spiu:SPICUR_06065 transaldolase gene gene3841 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03842 BSBS38_03843 BSBS38_03843 fbaA fbaA 3592336 3593193 - Fructose-bisphosphate aldolase Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1%2C6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis%3B Belongs to the class II fructose-bisphosphate aldolase family%3B KEGG: bsu:BSU37120 fructose-bisphosphate aldolase%2C class II gene gene3842 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03843 BSBS38_03844 BSBS38_03844 BSBS38_03844 3593374 3593748 - Sporulation initiation phosphotransferase Key element in the phosphorelay regulating sporulation initiation. Phosphorylation of spo0B during sporulation initiation. Contains 1 response regulatory domain gene gene3843 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03844 BSBS38_03845 BSBS38_03845 BSBS38_03845 3593914 3594435 + uncharacterized protein gene gene3844 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03845 BSBS38_03846 BSBS38_03846 BSBS38_03846 3594539 3595399 - Putative transposase InsO for insertion sequence element IS911B Involved in the transposition of the insertion sequence IS911B. Contains 1 integrase catalytic domain gene gene3845 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03846 BSBS38_03847 BSBS38_03847 BSBS38_03847 3595396 3595728 - hypothetical protein gene gene3846 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03847 BSBS38_03848 BSBS38_03848 pyrG pyrG 3595830 3597437 - CTP synthase (glutamine hydrolyzing) Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B Belongs to the CTP synthase family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: sbw:TGUWTKB_3070 CTP synthase gene gene3847 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03848 BSBS38_03849 BSBS38_03849 BSBS38_03849 3597679 3598185 - putative DNA-directed RNA polymerase subunit delta Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit%2C RNAP displays an increased specificity of transcription%2C a decreased affinity for nucleic acids%2C and an increased efficiency of RNA synthesis because of enhanced recycling%3B Belongs to the RpoE family gene gene3848 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03849 BSBS38_03850 BSBS38_03850 BSBS38_03850 3598368 3599507 - Acyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: par:Psyc_0901 null%3B With other acceptors gene gene3849 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03850 BSBS38_03851 BSBS38_03851 BSBS38_03851 3599504 3601621 - uncharacterized protein Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: gfo:GFO_1637 null%3B Oxidoreductases gene gene3850 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03851 BSBS38_03852 BSBS38_03852 BSBS38_03852 3601776 3602972 + Minor cardiolipin synthase ClsB Involved in the biosynthesis of cardiolipin%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bsu:BSU37190 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3851 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03852 BSBS38_03853 BSBS38_03853 uvsE uvsE 3602985 3603947 + UV DNA damage endonuclease Component in a DNA repair pathway. Removal of UV LIGHT damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion (By similarity)%3B Belongs to the uve1/UvsE family%3B KEGG: bsu:BSU37200 UV DNA damage endonuclease%3B Hydrolases gene gene3852 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03853 BSBS38_03854 BSBS38_03854 BSBS38_03854 3604342 3604866 - Dihydrofolate reductase To B. subtilis YyaP%3B KEGG: sgo:SGO_0348 dihydrofolate reductase gene gene3853 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03854 BSBS38_03855 BSBS38_03855 BSBS38_03855 3604876 3606339 - putative ABC transporter ATP-binding protein YwjA Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3854 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03855 BSBS38_03856 BSBS38_03856 BSBS38_03856 3606347 3606598 - putative ABC transporter ATP-binding protein YwjA Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3855 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03856 BSBS38_03857 BSBS38_03857 BSBS38_03857 3606687 3608189 - putative cardiolipin synthase YwiE Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity). May have a role in the heat shock response since the level of the transcript of ywiE increases after a heat shock%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bsu:BSU37240 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3856 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03857 BSBS38_03858 BSBS38_03858 narI narI 3608668 3609339 - Nitrate reductase KEGG: bsu:BSU37250 nitrate reductase gamma subunit gene gene3857 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03858 BSBS38_03859 BSBS38_03859 BSBS38_03859 3609336 3609890 - putative nitrate reductase molybdenum cofactor assembly chaperone NarJ Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase%3B Belongs to the NarJ/NarW family gene gene3858 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03859 BSBS38_03860 BSBS38_03860 narH narH 3609916 3611379 - Nitrate reductase Contains 3 4Fe-4S ferredoxin-type domains%3B KEGG: sod:Sant_0172 nitrate reductase beta subunit%3B overlaps another CDS with the same product name gene gene3859 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03860 BSBS38_03861 BSBS38_03861 narG narG 3611369 3615055 - Nitrate reductase The alpha chain is the actual site of nitrate reduction. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU37280 nitrate reductase alpha subunit%3B overlaps another CDS with the same product name gene gene3860 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03861 BSBS38_03862 BSBS38_03862 BSBS38_03862 3615251 3615727 - putative transcription regulator ArfM Activates%2C in anaerobic conditions%2C the transcription of the fermentative operons lctEP and alsDS%2C of the hmp gene encoding a flavohemoglobin-like protein%2C the nitrite reductase operon nasDE and the heme biosynthesis genes hemN and hemZ gene gene3861 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03862 BSBS38_03863 BSBS38_03863 BSBS38_03863 3615871 3616590 + uncharacterized protein To H. influenzae HI_1626 gene gene3862 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03863 BSBS38_03864 BSBS38_03864 BSBS38_03864 3616622 3617338 - Anaerobic regulatory protein It is involved in the activation of genes necessary for anaerobic respiration. Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene3863 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03864 BSBS38_03865 BSBS38_03865 BSBS38_03865 3617436 3618665 - Nitrite extrusion protein Involved in excretion of nitrite produced by the dissimilatory reduction of nitrate. Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene3864 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03865 BSBS38_03866 BSBS38_03866 rarS rarS 3618759 3620429 - Arginine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU37330 arginyl-tRNA synthetase gene gene3865 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03866 BSBS38_03867 BSBS38_03867 BSBS38_03867 3620426 3620854 - putative beta-barrel protein YwiB gene gene3866 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03867 BSBS38_03868 BSBS38_03868 BSBS38_03868 3621167 3621298 + Subtilosin-A Has bacteriocidal activity against some Gram-positive bacteria such as Listeria%2C some species of Bacillus and E. faecium%3B Belongs to the bacteriocin class V family gene gene3867 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03868 BSBS38_03869 BSBS38_03869 BSBS38_03869 3621432 3622778 + Antilisterial bacteriocin subtilosin biosynthesis protein AlbA Required for production of the bacteriocin subtilosin. May activate a metalloenzyme that catalyzes a modification of prosubtilosin gene gene3868 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03869 BSBS38_03870 BSBS38_03870 BSBS38_03870 3622791 3622952 + Antilisterial bacteriocin subtilosin biosynthesis protein AlbB Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin gene gene3869 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03870 BSBS38_03871 BSBS38_03871 BSBS38_03871 3622949 3623668 + Putative ABC transporter ATP-binding protein AlbC Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3870 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03871 BSBS38_03872 BSBS38_03872 BSBS38_03872 3623661 3624971 + Antilisterial bacteriocin subtilosin biosynthesis protein AlbD Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin gene gene3871 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03872 BSBS38_03873 BSBS38_03873 BSBS38_03873 3624937 3626121 + Antilisterial bacteriocin subtilosin biosynthesis protein AlbE Involved in the production of the bacteriocin subtilosin gene gene3872 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03873 BSBS38_03874 BSBS38_03874 BSBS38_03874 3626126 3627406 + Putative zinc protease AlbF Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin (By similarity)%3B Belongs to the peptidase M16 family%3B KEGG: syc:syc2110_d zinc protease%3B Metalloendopeptidases gene gene3873 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03874 BSBS38_03875 BSBS38_03875 BSBS38_03875 3627403 3628104 + Antilisterial bacteriocin subtilosin biosynthesis protein AlbG Involved in the production of the bacteriocin subtilosin gene gene3874 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03875 BSBS38_03876 BSBS38_03876 BSBS38_03876 3628110 3629486 - uncharacterized protein gene gene3875 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03876 BSBS38_03877 BSBS38_03877 BSBS38_03877 3629525 3630880 - Non-specific serine/threonine protein kinase KEGG: ncy:NOCYR_2137 serine/threonine protein kinase%2C bacterial gene gene3876 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03877 BSBS38_03878 BSBS38_03878 rapF rapF 3631110 3632255 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU37460 response regulator aspartate phosphatase F%3B Acting on ester bonds gene gene3877 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03878 BSBS38_03879 BSBS38_03879 BSBS38_03879 3632239 3632358 + Phosphatase RapF inhibitor Inhibitor of the activity of phosphatase RapF. Belongs to the phr family gene gene3878 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03879 BSBS38_03880 BSBS38_03880 BSBS38_03880 3632456 3633013 + uncharacterized protein gene gene3879 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03880 BSBS38_03881 BSBS38_03881 speB speB 3632948 3633820 - Agmatinase Catalyzes the formation of putrescine from agmatine%3B Belongs to the arginase family. Agmatinase subfamily%3B KEGG: bsu:BSU37490 agmatinase gene gene3880 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03881 BSBS38_03882 BSBS38_03882 speE speE 3633881 3634711 - Spermidine synthase Involved in the cell growth and proliferation. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1%2C4-diaminobutane) to yield spermidine (Probable)%3B Belongs to the spermidine/spermine synthase family%3B Contains 1 PABS (polyamine biosynthesis) domain%3B KEGG: bsu:BSU37500 spermidine synthase gene gene3881 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03882 BSBS38_03883 BSBS38_03883 BSBS38_03883 3634914 3636989 + Penicillin-binding protein 2D Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall%2C the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene3882 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03883 BSBS38_03884 BSBS38_03884 BSBS38_03884 3637282 3637800 - uncharacterized protein gene gene3883 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03884 BSBS38_03885 BSBS38_03885 BSBS38_03885 3637814 3638473 - Putative zinc metalloprotease YwhC Belongs to the peptidase M50B family gene gene3884 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03885 BSBS38_03886 BSBS38_03886 BSBS38_03886 3638582 3638770 + 2-hydroxymuconate tautomerase Catalyzes both 1%2C3- and 1%2C5-keto-enol tautomerization of the diacid 2-hydroxymuconate (2-hydroxy-2%2C4-hexadienedioate) to produce 2-oxo-4-hexenedioate. This reaction is highly stereoselective and produces a mixture of stereoisomers%2C where the (3S)-isomer of 2-oxo-4-hexenedioate predominates. Also catalyzes the tautomerization of 2-hydroxymuconate to 2-oxo-3-hexenedioate%2C however this reaction is slower and occurs after the tautomerization of 2-hydroxymuconate to 2-oxo-4-hexenedioate. Using 2-hydroxy-2%2C4-pentadienoate%2C phenylenolpyruvate%2C (p- hydroxyphenyl)-enolpyruvate and 2-hydroxy-2%2C4-heptadiene-1%2C7- dioate%2C YwhB is a highly efficient 1%2C3-keto-enol tautomerase%2C but clearly not a 1%2C5-keto-enol tautomerase. Tautomerization of the two monoacids 2-hydroxy-2%2C4-pentadienoate and phenylenolpyruvate produces a mixture of stereoisomers%2C where the (3R)-isomers predominate%3B Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: bsu:BSU37540 4-oxalocrotonate tautomerase gene gene3885 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03886 BSBS38_03887 BSBS38_03887 BSBS38_03887 3638813 3639232 - putative HTH-type transcriptional regulator YwhA Contains 1 HTH marR-type DNA-binding domain gene gene3886 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03887 BSBS38_03888 BSBS38_03888 BSBS38_03888 3639352 3641268 - Threonine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU37560 threonyl-tRNA synthetase gene gene3887 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03888 BSBS38_03889 BSBS38_03889 BSBS38_03889 3641878 3642033 - hypothetical protein gene gene3888 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03889 BSBS38_03890 BSBS38_03890 BSBS38_03890 3642113 3643513 - Methylenomycin A resistance protein Resistance to the epoxide antibiotic methylenomycin. Belongs to the major facilitator superfamily. EmrB family gene gene3889 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03890 BSBS38_03891 BSBS38_03891 BSBS38_03891 3643513 3643983 - Putative HTH-type transcriptional regulator YwgB Contains 1 HTH rrf2-type DNA-binding domain gene gene3890 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03891 BSBS38_03892 BSBS38_03892 BSBS38_03892 3644095 3644595 - uncharacterized protein gene gene3891 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03892 BSBS38_03893 BSBS38_03893 BSBS38_03893 3644631 3645932 - uncharacterized protein Contains 1 HD domain gene gene3892 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03893 BSBS38_03894 BSBS38_03894 BSBS38_03894 3646094 3646318 - UPF0741 protein Belongs to the UPF0741 family gene gene3893 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03894 BSBS38_03895 BSBS38_03895 BSBS38_03895 3646533 3647309 + Prespore-specific transcriptional regulator RsfA Seems to improve the efficiency of sporulation by fine- tuning the expression of genes in the sigma F regulon%2C particularly the timing of their expression. Negatively regulates spoIIR and its own synthesis. Contains 1 Myb-like domain gene gene3894 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03895 BSBS38_03896 BSBS38_03896 BSBS38_03896 3647453 3648343 - putative transporter YwfM Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3895 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03896 BSBS38_03897 BSBS38_03897 lipL lipL 3648512 3649357 - Octanoyl-[GcvH]:protein N-octanoyltransferase Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes%3B Belongs to the octanoyltransferase LipL family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU37640 octanoyl-(GcvH):protein N-octanoyltransferase gene gene3896 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03897 BSBS38_03898 BSBS38_03898 BSBS38_03898 3649406 3650305 - HTH-type transcriptional regulator CysL Transcriptional activator of the cysJI operon which is involved in sulfur assimilation. Also negatively regulates its own transcription%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3897 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03898 BSBS38_03899 BSBS38_03899 BSBS38_03899 3650451 3651422 - Phosphate acetyltransferase Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bsu:BSU37660 phosphate acetyltransferase gene gene3898 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03899 BSBS38_03900 BSBS38_03900 BSBS38_03900 3651692 3652456 + Chlorite O(2)-lyase May function as heme-dependent peroxidase%3B Belongs to the UPF0447 family%3B KEGG: bsr:I33_3915 chlorite dismutase gene gene3899 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03900 BSBS38_03901 BSBS38_03901 bacG bacG 3652589 3653368 + Bacilysin biosynthesis oxidoreductase YwfH Along with the bacABCDE operon is involved in bacilysin biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU37680 bacilysin biosynthesis oxidoreductase BacG%3B Oxidoreductases gene gene3900 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03901 BSBS38_03902 BSBS38_03902 bacF bacF 3653384 3654598 - putative aspartate aminotransferase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU37690 bacilysin biosynthesis transaminase BacF%3B Transaminases gene gene3901 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03902 BSBS38_03903 BSBS38_03903 BSBS38_03903 3654599 3655783 - Putative bacilysin exporter BacE Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic (By similarity)%3B Belongs to the major facilitator superfamily gene gene3902 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03903 BSBS38_03904 BSBS38_03904 bacD bacD 3655780 3657198 - L-alanine--L-anticapsin ligase Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin%2C an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)%3B Contains 1 ATP-grasp domain%3B KEGG: bsu:BSU37710 L-alanine-L-anticapsin ligase gene gene3903 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03904 BSBS38_03905 BSBS38_03905 bacC bacC 3657217 3657978 - Dihydroanticapsin 7-dehydrogenase Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin%2C an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the dehydrogenation of the C7-hydroxyl group in the 4S- tetrahydrotyrosine (4S-H4Tyr) to yield anticapsin (epoxycyclohexanonyl-Ala)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU37720 dihydroanticapsin dehydrogenase gene gene3904 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03905 BSBS38_03906 BSBS38_03906 bacB bacB 3657981 3658688 - Bacilysin biosynthesis protein BacB Part of the bacABCDE operon responsible for the biosynthesis of bacilysin%3B KEGG: bsu:BSU37730 bacilysin biosynthesis protein BacB%3B Isomerases gene gene3905 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03906 BSBS38_03907 BSBS38_03907 BSBS38_03907 3658678 3658980 - Bacilysin biosynthesis protein BacA Part of the bacABCDE operon responsible for the biosynthesis of bacilysin%3B KEGG: bsu:BSU37740 bacilysin biosynthesis protein BacA%3B Carboxy-lyases gene gene3906 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03907 BSBS38_03908 BSBS38_03908 BSBS38_03908 3659443 3660681 - putative MFS-type transporter YwfA Belongs to the major facilitator superfamily gene gene3907 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03908 BSBS38_03909 BSBS38_03909 BSBS38_03909 3660891 3662303 - Amino-acid permease RocC Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3908 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03909 BSBS38_03910 BSBS38_03910 BSBS38_03910 3662303 3664003 - Protein RocB gene gene3909 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03910 BSBS38_03911 BSBS38_03911 BSBS38_03911 3664077 3665624 - L-glutamate gamma-semialdehyde dehydrogenase Belongs to the aldehyde dehydrogenase family. RocA subfamily%3B KEGG: bsu:BSU37780 1-pyrroline-5-carboxylate dehydrogenase gene gene3910 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03911 BSBS38_03912 BSBS38_03912 BSBS38_03912 3665851 3667125 - Glutamate dehydrogenase Devoted to catabolic function of glutamate (and other amino acids of the glutamate family) utilization as sole nitrogen source. It is not involved in anabolic function of glutamate biosynthesis since B. subtilis possesses only one route of glutamate biosynthesis from ammonia%2C catalyzed by glutamate synthase. RocG is unable to utilize glutamate or glutamine as sole carbon source and to synthesize glutamate%2C but it is involved in the utilization of arginine%2C and proline as carbon or nitrogen source. The catabolic RocG is essential for controlling gltAB expression via an inhibitory interactions with the transcriptional regulator GltC in response to the availability of sugars%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bsu:BSU37790 glutamate dehydrogenase gene gene3911 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03912 BSBS38_03913 BSBS38_03913 BSBS38_03913 3667302 3667766 - uncharacterized protein To B. subtilis YuaB gene gene3912 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03913 BSBS38_03914 BSBS38_03914 rfbC rfbC 3668089 3668544 - dTDP-4-dehydrorhamnose 3%2C5-epimerase To dTDP-4-dehydrorhamnose reductase%3B KEGG: sat:SYN_00576 dTDP-4-dehydrorhamnose 3%2C5-epimerase gene gene3913 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03914 BSBS38_03915 BSBS38_03915 rfbD rfbD 3668537 3668935 - dTDP-4-dehydrorhamnose reductase Belongs to the dTDP-4-dehydrorhamnose reductase family%3B KEGG: bsu:BSU37820 dTDP-4-dehydrorhamnose reductase gene gene3914 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03915 BSBS38_03916 BSBS38_03916 BSBS38_03916 3668980 3669387 - dTDP-4-dehydrorhamnose reductase Belongs to the dTDP-4-dehydrorhamnose reductase family%3B KEGG: mvs:MVIS_2688 dTDP-4-dehydrorhamnose reductase gene gene3915 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03916 BSBS38_03917 BSBS38_03917 rfbB rfbB 3669401 3670348 - dTDP-glucose 4%2C6-dehydratase Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation%2C dehydration and reduction%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily%3B KEGG: hcs:FF32_18495 dTDP-glucose 4%2C6-dehydratase gene gene3916 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03917 BSBS38_03918 BSBS38_03918 rfbA rfbA 3670348 3671088 - Glucose-1-phosphate thymidylyltransferase Catalyzes the formation of dTDP-glucose%2C from dTTP and glucose 1-phosphate in the novobiocin biosynthesis pathway%2C an aminocoumarin family antibiotic that targets bacterial DNA gyrases. Belongs to the glucose-1-phosphate thymidylyltransferase family%3B KEGG: eco:b3789 glucose-1-phosphate thymidylyltransferase gene gene3917 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03918 BSBS38_03919 BSBS38_03919 BSBS38_03919 3671113 3672132 - Spore coat polysaccharide biosynthesis protein SpsG To M. jannaschii MJ1062 gene gene3918 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03919 BSBS38_03920 BSBS38_03920 BSBS38_03920 3672135 3672857 - Spore coat polysaccharide biosynthesis protein SpsF Belongs to the CMP-NeuNAc synthase family gene gene3919 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03920 BSBS38_03921 BSBS38_03921 BSBS38_03921 3672850 3673971 - N%2CN'-diacetyllegionaminate synthase Contains 1 AFP-like domain%3B KEGG: txy:Thexy_1876 N%2CN'-diacetyllegionaminate synthase gene gene3920 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03921 BSBS38_03922 BSBS38_03922 rffC rffC 3673971 3674840 - dTDP-4-amino-4%2C6-dideoxy-D-galactose acyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: bae:BATR1942_16840 dTDP-4-amino-4%2C6-dideoxy-D-galactose acyltransferase gene gene3921 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03922 BSBS38_03923 BSBS38_03923 arnB arnB 3674841 3676010 - UDP-4-amino-4-deoxy-L-arabinose aminotransferase Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: yru:BD65_481 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase gene gene3922 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03923 BSBS38_03924 BSBS38_03924 BSBS38_03924 3676031 3677410 - Spore coat polysaccharide biosynthesis protein SpsB gene gene3923 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03924 BSBS38_03925 BSBS38_03925 pglI pglI 3677460 3678230 - GalNAc(5)-diNAcBac-PP-undecaprenol beta-1%2C3-glucosyltransferase Glucosyltransferase that adds he final branching glucose to complete the final heptasaccharide structure in the N-linked protein glycosylation pathway%3B Belongs to the glycosyltransferase 2 family%3B KEGG: cje:Cj1128c GalNAc5-diNAcBac-PP-undecaprenol beta-1%2C3-glucosyltransferase gene gene3924 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03925 BSBS38_03926 BSBS38_03926 BSBS38_03926 3678549 3679094 + Spore coat protein GerQ Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA gene gene3925 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03926 BSBS38_03927 BSBS38_03927 BSBS38_03927 3679138 3679509 - Proline--tRNA ligase Belongs to the UPF0382 family%3B KEGG: gsl:Gasu_24190 prolyl-tRNA synthetase gene gene3926 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03927 BSBS38_03928 BSBS38_03928 BSBS38_03928 3679571 3680893 - Putative purine permease YwdJ Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene3927 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03928 BSBS38_03929 BSBS38_03929 BSBS38_03929 3680913 3681230 - uncharacterized protein gene gene3928 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03929 BSBS38_03930 BSBS38_03930 BSBS38_03930 3681398 3682768 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU37960 aldehyde dehydrogenase (NAD+) gene gene3929 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03930 BSBS38_03931 BSBS38_03931 BSBS38_03931 3682793 3683470 - Uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine%3B Belongs to the uracil-DNA glycosylase family%3B KEGG: bsu:BSU37970 uracil-DNA glycosylase gene gene3930 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03931 BSBS38_03932 BSBS38_03932 wbbL wbbL 3683484 3684290 - N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: fre:Franean1_5877 N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase gene gene3931 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03932 BSBS38_03933 BSBS38_03933 BSBS38_03933 3684380 3684913 - uncharacterized protein gene gene3932 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03933 BSBS38_03934 BSBS38_03934 BSBS38_03934 3684961 3685596 - uncharacterized protein gene gene3933 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03934 BSBS38_03935 BSBS38_03935 BSBS38_03935 3685589 3685927 - Putative DNA-binding protein YwzG gene gene3934 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03935 BSBS38_03936 BSBS38_03936 pdxK pdxK 3686071 3686886 + Pyridoxal kinase Phosphorylates B6 vitamer%3B functions in a salvage pathway. Uses pyridoxal%2C pyridoxine%2C and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate%3B Belongs to the ThiD family%3B KEGG: bsu:BSU38020 pyridoxine kinase gene gene3935 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03936 BSBS38_03937 BSBS38_03937 BSBS38_03937 3686977 3687225 - uncharacterized protein gene gene3936 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03937 BSBS38_03938 BSBS38_03938 sacA sacA 3687319 3688758 - Beta-fructofuranosidase Belongs to the glycosyl hydrolase 32 family%3B KEGG: bsu:BSU38040 beta-fructofuranosidase gene gene3937 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03938 BSBS38_03939 BSBS38_03939 bglF bglF 3688755 3690140 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport (By similarity)%3B Acts as both a kinase and a phosphatase on SacT%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: pmr:PMI2226 PTS system%2C beta-glucosides-specific IIA component gene gene3938 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03939 BSBS38_03940 BSBS38_03940 BSBS38_03940 3690442 3691212 + putative transporter YwcJ Belongs to the FNT transporter (TC 2. A. 44) family gene gene3939 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03940 BSBS38_03941 BSBS38_03941 BSBS38_03941 3691251 3692081 - SacPA operon antiterminator Mediates positive regulation of the sacPA operon by functioning as an antiterminator factor of transcription. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene3940 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03941 BSBS38_03942 BSBS38_03942 BSBS38_03942 3692121 3692423 - uncharacterized protein gene gene3941 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03942 BSBS38_03943 BSBS38_03943 BSBS38_03943 3692952 3695372 + Minor extracellular protease vpr Not required for growth or sporulation. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU38090 minor extracellular serine protease Vpr%3B Serine endopeptidases gene gene3942 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03943 BSBS38_03944 BSBS38_03944 BSBS38_03944 3695410 3696411 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains%3B KEGG: gfo:GFO_3489 null%3B Oxidoreductases gene gene3943 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03944 BSBS38_03945 BSBS38_03945 nfsA nfsA 3696585 3697334 - NADPH-flavin oxidoreductase Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Belongs to the flavin oxidoreductase frp family%3B KEGG: ppr:PBPRA2417 nitroreductase%3B Oxidoreductases gene gene3944 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03945 BSBS38_03946 BSBS38_03946 BSBS38_03946 3697440 3698621 - Rod shape-determining protein RodA Required for the maintenance of the rod cell shape. Also essential for the elongation of the lateral wall of the cell%3B Belongs to the SEDS family. RodA subfamily gene gene3945 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03946 BSBS38_03947 BSBS38_03947 BSBS38_03947 3698830 3699975 - hypothetical protein gene gene3946 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03947 BSBS38_03948 BSBS38_03948 BSBS38_03948 3700207 3700467 + Spore morphoproteinis and germination protein YwcE Required for proper spore morphogenesis. Important for spore germination (By similarity)%3B Belongs to the YwcE family gene gene3947 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03948 BSBS38_03949 BSBS38_03949 qoxD qoxD 3700509 3700883 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bsu:BSU38140 cytochrome aa3-600 menaquinol oxidase subunit IV gene gene3948 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03949 BSBS38_03950 BSBS38_03950 qoxC qoxC 3700885 3701499 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bsu:BSU38150 cytochrome aa3-600 menaquinol oxidase subunit III gene gene3949 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03950 BSBS38_03951 BSBS38_03951 qoxB qoxB 3701513 3703462 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bsu:BSU38160 cytochrome aa3-600 menaquinol oxidase subunit I gene gene3950 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03951 BSBS38_03952 BSBS38_03952 qoxA qoxA 3703490 3704491 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. Belongs to the cytochrome c oxidase subunit 2 family%3B KEGG: bsut:BSUB_04053 cytochrome aa3-600 menaquinol oxidase subunit II gene gene3951 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03952 BSBS38_03953 BSBS38_03953 BSBS38_03953 3704968 3705216 + UPF0410 protein YdaS Belongs to the UPF0410 family gene gene3952 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03953 BSBS38_03954 BSBS38_03954 galT galT 3705287 3706828 - UDP-glucose--hexose-1-phosphate uridylyltransferase Belongs to the galactose-1-phosphate uridylyltransferase type 2 family%3B KEGG: bsu:BSU38190 UDPglucose--hexose-1-phosphate uridylyltransferase gene gene3953 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03954 BSBS38_03955 BSBS38_03955 galK galK 3706832 3708004 - Galactokinase Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)%3B Belongs to the GHMP kinase family. GalK subfamily%3B KEGG: bsu:BSU38200 galactokinase gene gene3954 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03955 BSBS38_03956 BSBS38_03956 BSBS38_03956 3708082 3708486 - Cell wall teichoic acid glycosylation protein Involved in the decoration of cell wall teichoic acid with galactose and glucose%3B Belongs to the GtrA family gene gene3955 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03956 BSBS38_03957 BSBS38_03957 BSBS38_03957 3708483 3709154 - putative HTH-type transcriptional regulator YwcC Contains 1 HTH tetR-type DNA-binding domain gene gene3956 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03957 BSBS38_03958 BSBS38_03958 BSBS38_03958 3709509 3709667 + Transcriptional regulator SlrA Required specifically for induction of eps and yqxM operons by antagonizing SinR. Regulates SlrR activity. Controls the initiation of biofilm formation%3B Contains 1 Sin domain gene gene3957 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03958 BSBS38_03959 BSBS38_03959 BSBS38_03959 3710110 3710418 + uncharacterized protein gene gene3958 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03959 BSBS38_03960 BSBS38_03960 BSBS38_03960 3710415 3711956 + putative symporter YwcA Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene3959 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03960 BSBS38_03961 BSBS38_03961 BSBS38_03961 3711986 3712588 - uncharacterized protein gene gene3960 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03961 BSBS38_03962 BSBS38_03962 efeB efeB 3712871 3714121 - putative deferrochelatase/peroxidase EfeN Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity)%3B Belongs to the DyP-type peroxidase family%3B KEGG: bsu:BSU38260 deferrochelatase/peroxidase EfeB%3B Peroxidases gene gene3961 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03962 BSBS38_03963 BSBS38_03963 BSBS38_03963 3714140 3715297 - putative iron uptake system component EfeM Involved in iron uptake%3B Belongs to the EfeM/EfeO family gene gene3962 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03963 BSBS38_03964 BSBS38_03964 BSBS38_03964 3715294 3716736 - Ferrous iron permease EfeU Uptake of Fe(2+) ions across the membrane%3B Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9. A. 10. 1) family gene gene3963 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03964 BSBS38_03965 BSBS38_03965 thiE thiE 3716893 3717561 - Thiamine phosphate synthase Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)%3B Belongs to the thiamine-phosphate synthase family%3B KEGG: bsu:BSU38290 thiamine-phosphate pyrophosphorylase gene gene3964 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03965 BSBS38_03966 BSBS38_03966 thiM thiM 3717558 3718376 - Hydroxyethylthiazole kinase Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)%3B Belongs to the Thz kinase family%3B KEGG: bsu:BSU38300 hydroxyethylthiazole kinase gene gene3965 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03966 BSBS38_03967 BSBS38_03967 BSBS38_03967 3718384 3719289 - putative HTH-type transcriptional regulator YwbI Contains 1 HTH lysR-type DNA-binding domain gene gene3966 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03967 BSBS38_03968 BSBS38_03968 BSBS38_03968 3719395 3719781 + Holin-like protein CidA Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell%2C the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment%2C CidA possibly oligomerizes within the bacterial cell membrane%2C creating lesions that disrupt the proton motive force%2C which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential%3B Belongs to the CidA/LrgA family. CidA subfamily gene gene3967 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03968 BSBS38_03969 BSBS38_03969 BSBS38_03969 3719763 3720440 + uncharacterized protein Belongs to the YohK (E. coli)/YwbG (IPA-22R) (B. subtilis) family gene gene3968 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03969 BSBS38_03970 BSBS38_03970 BSBS38_03970 3720546 3721748 + putative transporter YwbF Belongs to the LacY/RafB permease family. HcaT subfamily gene gene3969 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03970 BSBS38_03971 BSBS38_03971 BSBS38_03971 3721782 3721979 + uncharacterized protein gene gene3970 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03971 BSBS38_03972 BSBS38_03972 rlmI rlmI 3722014 3723201 - 23S rRNA (cytosine(1962)-C(5))-methyltransferase Belongs to the methyltransferase superfamily. RlmI family%3B Contains 1 PUA domain%3B KEGG: bsu:BSU38360 23S rRNA (cytosine1962-C5)-methyltransferase gene gene3971 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03972 BSBS38_03973 BSBS38_03973 BSBS38_03973 3723322 3723702 + Lactoylglutathione lyase Belongs to the glyoxalase I family%3B KEGG: bsu:BSU38370 lactoylglutathione lyase gene gene3972 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03973 BSBS38_03974 BSBS38_03974 BSBS38_03974 3723741 3724418 - uncharacterized protein gene gene3973 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03974 BSBS38_03975 BSBS38_03975 BSBS38_03975 3724510 3725832 - Putative permease IIC component YwbA The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B Contains 1 PTS EIIC type-3 domain gene gene3974 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03975 BSBS38_03976 BSBS38_03976 BSBS38_03976 3726059 3727867 + Minor extracellular protease Epr Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU38400 minor extracellular protease Epr%3B Serine endopeptidases gene gene3975 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03976 BSBS38_03977 BSBS38_03977 BSBS38_03977 3728422 3729801 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Negatively regulates SacY activity by catalyzing its phosphorylation on 'His-99'%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system may be involved in sucrose transport%3B Negatively regulates SacY%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU38410 PTS system%2C sucrose-specific IIB component gene gene3976 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03977 BSBS38_03978 BSBS38_03978 BSBS38_03978 3729855 3730697 + Levansucrase and sucrase synthesis operon antiterminator In the presence of sucrose%2C SacY is activated and prevents premature termination of transcription by binding to a RNA-antiterminator (RAT) sequence (partially overlapping with the terminator sequence) located upstream of the sacB gene. Formation of the SacY-RAT complex prevents alternative formation of the terminator%2C allowing transcription of the sacB gene. In the absence of sucrose%2C inhibition of SacY activity by SacX leads to termination of transcription%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene3977 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03978 BSBS38_03979 BSBS38_03979 waaO waaO 3730747 3731607 - General stress protein Belongs to the glycosyltransferase 8 family%3B KEGG: eca:ECA0158 UDP-glucose:(glucosyl)LPS alpha-1%2C3-glucosyltransferase%3B Hexosyltransferases gene gene3978 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03979 BSBS38_03980 BSBS38_03980 BSBS38_03980 3731718 3732431 - uncharacterized protein gene gene3979 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03980 BSBS38_03981 BSBS38_03981 BSBS38_03981 3732582 3733097 + putative HTH-type transcriptional regulator YwaE Contains 1 HTH marR-type DNA-binding domain gene gene3980 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03981 BSBS38_03982 BSBS38_03982 BSBS38_03982 3733351 3734589 + Tyrosine--tRNA ligase Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: bsu:BSU38460 tyrosyl-tRNA synthetase gene gene3981 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03982 BSBS38_03983 BSBS38_03983 BSBS38_03983 3734744 3736111 + Lactocepin Catalyzes the hydrolysis of a range of N-terminal amino acids%3B Belongs to the peptidase M28 family. M28B subfamily%3B KEGG: lhl:LBHH_1000 lactocepin gene gene3982 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03983 BSBS38_03984 BSBS38_03984 BSBS38_03984 3736141 3736773 - GTP diphosphokinase Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in response to changes in nutritional abundance. YwaC has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bsu:BSU38480 putative GTP pyrophosphokinase gene gene3983 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03984 BSBS38_03985 BSBS38_03985 BSBS38_03985 3736983 3737315 + hypothetical protein gene gene3984 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03985 BSBS38_03986 BSBS38_03986 BSBS38_03986 3737312 3738172 + Putative transposase InsO for insertion sequence element IS911B Involved in the transposition of the insertion sequence IS911B. Contains 1 integrase catalytic domain gene gene3985 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03986 BSBS38_03987 BSBS38_03987 menA menA 3738228 3739163 - 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase Conversion of 1%2C4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)%3B Belongs to the MenA family. Type 1 subfamily%3B KEGG: bsu:BSU38490 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase%3B 1%2C4-dihydroxy-2-naphthoate polyprenyltransferase gene gene3986 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03987 BSBS38_03988 BSBS38_03988 BSBS38_03988 3739610 3739759 + putative membrane protein YwzH gene gene3987 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03988 BSBS38_03989 BSBS38_03989 dltA dltA 3739777 3741288 + D-alanine--poly(phosphoribitol) ligase Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp. Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily%3B KEGG: bsu:BSU38500 D-alanine--poly(phosphoribitol) ligase subunit 1 gene gene3988 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03989 BSBS38_03990 BSBS38_03990 BSBS38_03990 3741285 3742472 + Protein DltB Could be involved in the transport of activated D- alanine through the membrane. Belongs to the membrane-bound acyltransferase family gene gene3989 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03990 BSBS38_03991 BSBS38_03991 dltC dltC 3742489 3742725 + D-alanine--poly(phosphoribitol) ligase Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA%3B Contains 1 acyl carrier domain%3B KEGG: bsu:BSU38520 D-alanine--poly(phosphoribitol) ligase subunit 2 gene gene3990 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03991 BSBS38_03992 BSBS38_03992 BSBS38_03992 3742725 3743903 + Protein DltD gene gene3991 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03992 BSBS38_03993 BSBS38_03993 dltE dltE 3743994 3744752 + putative oxidoreductase DltE Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sod:Sant_P0117 uncharacterized oxidoreductase%3B Oxidoreductases gene gene3992 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03993 BSBS38_03994 BSBS38_03994 BSBS38_03994 3744894 3745985 + Branched-chain-amino-acid transaminase Transaminates branched-chain amino acids and ketoglutarate%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU38550 branched-chain amino acid aminotransferase gene gene3993 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03994 BSBS38_03995 BSBS38_03995 celF celF 3746019 3747347 - 6-phospho-beta-glucosidase Hydrolyzes phospho-beta-glucosides%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bsu:BSU38560 6-phospho-beta-glucosidase gene gene3994 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03995 BSBS38_03996 BSBS38_03996 BSBS38_03996 3747344 3747676 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIA type-3 domain%3B KEGG: enc:ECL_02437 PTS system%2C cellobiose-specific IIA component gene gene3995 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03996 BSBS38_03997 BSBS38_03997 BSBS38_03997 3747695 3749053 - Lichenan permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIC type-3 domain gene gene3996 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03997 BSBS38_03998 BSBS38_03998 BSBS38_03998 3749069 3749377 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: ebi:EbC_39840 PTS system%2C cellobiose-specific IIB component gene gene3997 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03998 BSBS38_03999 BSBS38_03999 BSBS38_03999 3749506 3751431 - putative licABCH operon regulator Positive regulator of the licABCH operon. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene3998 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_03999 BSBS38_04000 BSBS38_04000 BSBS38_04000 3751594 3751710 - uncharacterized protein gene gene3999 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04000 BSBS38_04001 BSBS38_04001 BSBS38_04001 3751780 3752370 - DNA-3-methyladenine glycosylase II Belongs to the DNA glycosylase MPG family%3B KEGG: bsu:BSU38620 DNA-3-methyladenine glycosylase gene gene4000 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04001 BSBS38_04002 BSBS38_04002 BSBS38_04002 3752503 3754146 + Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: bsu:BSU38630 catalase gene gene4001 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04002 BSBS38_04003 BSBS38_04003 BSBS38_04003 3754250 3755452 + putative MFS-type transporter YxlH Belongs to the major facilitator superfamily. TCR/Tet family gene gene4002 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04003 BSBS38_04004 BSBS38_04004 BSBS38_04004 3755449 3756225 - putative transmembrane protein YxlG gene gene4003 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04004 BSBS38_04005 BSBS38_04005 BSBS38_04005 3756222 3757109 - Phosphonate-transporting ATPase Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: pao:Pat9b_2460 phosphonate transport system ATP-binding protein gene gene4004 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04005 BSBS38_04006 BSBS38_04006 BSBS38_04006 3757116 3757304 - Negative regulatory protein YxlE Together with YxlD is important for negative regulation of sigma Y activity gene gene4005 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04006 BSBS38_04007 BSBS38_04007 BSBS38_04007 3757301 3757507 - Negative regulatory protein YxlD Together with YxlE%2C is important for negative regulation of sigma Y activity%2C being the major negative regulator gene gene4006 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04007 BSBS38_04008 BSBS38_04008 BSBS38_04008 3757504 3757824 - uncharacterized protein gene gene4007 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04008 BSBS38_04009 BSBS38_04009 BSBS38_04009 3757817 3758353 - RNA polymerase sigma factor SigY Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of the sigY- yxlCDEFG operon upon nitrogen starvation. Also positively regulates ybgB%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene4008 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04009 BSBS38_04010 BSBS38_04010 BSBS38_04010 3758565 3759938 + Putative purine-cytosine permease YxlA Belongs to the purine-cytosine permease (2. A. 39) family gene gene4009 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04010 BSBS38_04011 BSBS38_04011 BSBS38_04011 3759953 3760783 - ADP-dependent NAD(P)H-hydrate dehydratase Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP%2C which is converted to AMP. Together with NAD(P)HX epimerase%2C which catalyzes the epimerization of the S- and R-forms%2C the enzyme allows the repair of both epimers of NAD(P)HX%2C a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration%3B Belongs to the NnrD/CARKD family%3B Contains 1 YjeF C-terminal domain%3B KEGG: bsu:BSU38720 ADP-dependent NAD(P)H-hydrate dehydratase gene gene4010 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04011 BSBS38_04012 BSBS38_04012 BSBS38_04012 3760869 3762596 - ATP-binding/permease protein CydD Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4011 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04012 BSBS38_04013 BSBS38_04013 BSBS38_04013 3762593 3764296 - ATP-binding/permease protein CydC Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4012 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04013 BSBS38_04014 BSBS38_04014 BSBS38_04014 3764296 3765312 - Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bsu:BSU38750 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene4013 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04014 BSBS38_04015 BSBS38_04015 BSBS38_04015 3765296 3766702 - Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene4014 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04015 BSBS38_04016 BSBS38_04016 BSBS38_04016 3767257 3768609 + Citrate/malate transporter Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporte%3B the number of protons transported is equal to the valence of the transported anions. Is strictly stereoselective%2C translocating only the (S)-enantiomer of malate. Belongs to the sodium:citrate (SCF) symporter family gene gene4015 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04016 BSBS38_04017 BSBS38_04017 BSBS38_04017 3768731 3770419 + Putative membrane metalloprotease YxkI Belongs to the peptidase M48 family gene gene4016 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04017 BSBS38_04018 BSBS38_04018 BSBS38_04018 3770477 3770677 + uncharacterized protein gene gene4017 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04018 BSBS38_04019 BSBS38_04019 pgaB pgaB 3770691 3771530 - Putative polysaccharide deacetylase YxkH Belongs to the polysaccharide deacetylase family%3B KEGG: bbe:BBR47_54040 biofilm PGA synthesis lipoprotein PgaB%3B Hydrolases gene gene4018 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04019 BSBS38_04020 BSBS38_04020 BSBS38_04020 3771637 3772734 - Maltodextrin import ATP-binding protein MsmX Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for energy coupling to the transport system (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4019 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04020 BSBS38_04021 BSBS38_04021 BSBS38_04021 3772855 3773748 - uncharacterized protein gene gene4020 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04021 BSBS38_04022 BSBS38_04022 BSBS38_04022 3773932 3775389 + Aldehyde dehydrogenase (NAD(+)) May contribute to protect cells against stress due to ethanol and related compounds. Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU38830 aldehyde dehydrogenase (NAD+) gene gene4021 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04022 BSBS38_04023 BSBS38_04023 BSBS38_04023 3775431 3776267 - UPF0750 membrane protein YxkD Belongs to the UPF0750 family gene gene4022 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04023 BSBS38_04024 BSBS38_04024 BSBS38_04024 3776604 3777623 - UDP-glucose 4-epimerase Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: eco:b0759 UDP-glucose 4-epimerase gene gene4023 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04024 BSBS38_04025 BSBS38_04025 BSBS38_04025 3777851 3778324 + uncharacterized protein gene gene4024 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04025 BSBS38_04026 BSBS38_04026 BSBS38_04026 3778342 3779553 + Histidine kinase Probable member of the two-component regulatory system YxjM/YxjL. May activate YxjL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: rge:RGE_19330 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene4025 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04026 BSBS38_04027 BSBS38_04027 BSBS38_04027 3779550 3780206 + Chemotaxis response regulator protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene4026 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04027 BSBS38_04028 BSBS38_04028 pepT pepT 3780256 3781488 + Tripeptide aminopeptidase Cleaves the N-terminal amino acid of tripeptides%3B Belongs to the peptidase M20B family%3B KEGG: ype:YPO1009 tripeptide aminopeptidase gene gene4027 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04028 BSBS38_04029 BSBS38_04029 BSBS38_04029 3781593 3781721 + hypothetical protein gene gene4028 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04029 BSBS38_04030 BSBS38_04030 BSBS38_04030 3782011 3782274 + uncharacterized protein gene gene4029 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04030 BSBS38_04031 BSBS38_04031 BSBS38_04031 3782403 3782891 + uncharacterized protein Belongs to the LOR family gene gene4030 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04031 BSBS38_04032 BSBS38_04032 BSBS38_04032 3783146 3784279 + 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase To B. subtilis YxjG%3B KEGG: bss:BSUW23_19315 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene4031 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04032 BSBS38_04033 BSBS38_04033 BSBS38_04033 3784532 3785668 + 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase To B. subtilis YxjH%3B KEGG: bss:BSUW23_19320 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene4032 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04033 BSBS38_04034 BSBS38_04034 butA butA 3785720 3786493 - 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2 Involved in the toluene-4-sulfonate degradation pathway. Does not discriminate between the sulfonate and the carboxyl substituents and can also be involved in the p-toluenecarboxylate degradation pathway%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: cbw:RR42_s0191 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene4033 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04034 BSBS38_04035 BSBS38_04035 BSBS38_04035 3786510 3787160 - 3-oxoacid CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit B family%3B KEGG: bsu:BSU38980 3-oxoacid CoA-transferase subunit B%3B overlaps another CDS with the same product name gene gene4034 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04035 BSBS38_04036 BSBS38_04036 scoA scoA 3787157 3787873 - 3-oxoacid CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit A family%3B KEGG: bsu:BSU38990 3-oxoacid CoA-transferase subunit A%3B overlaps another CDS with the same product name gene gene4035 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04036 BSBS38_04037 BSBS38_04037 BSBS38_04037 3787897 3789315 - putative transporter YxjC Belongs to the CitM (TC 2. A. 11) transporter family gene gene4036 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04037 BSBS38_04038 BSBS38_04038 BSBS38_04038 3789469 3790317 - 23S rRNA (guanine(745)-N(1))-methyltransferase Belongs to the methyltransferase superfamily. RlmA family%3B KEGG: bsu:BSU39010 23S rRNA (guanine745-N1)-methyltransferase gene gene4037 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04038 BSBS38_04039 BSBS38_04039 BSBS38_04039 3790933 3792126 + Pyrimidine nucleoside transport protein Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene4038 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04039 BSBS38_04040 BSBS38_04040 BSBS38_04040 3792168 3792839 - uncharacterized protein gene gene4039 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04040 BSBS38_04041 BSBS38_04041 BSBS38_04041 3792984 3793274 - uncharacterized protein gene gene4040 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04041 BSBS38_04042 BSBS38_04042 BSBS38_04042 3793324 3795384 - Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation. Belongs to the catalase family. HPII subfamily%3B KEGG: bsu:BSU39050 catalase gene gene4041 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04042 BSBS38_04043 BSBS38_04043 BSBS38_04043 3795586 3796866 + Mg(2+)/citrate complex secondary transporter Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+)%2C Mn(2+)%2C Co(2+)%2C and Zn(2+). Belongs to the CitM (TC 2. A. 11) transporter family gene gene4042 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04043 BSBS38_04044 BSBS38_04044 exoK exoK 3797025 3797753 - Beta-glucanase Belongs to the glycosyl hydrolase 16 family%3B Contains 1 GH16 (glycosyl hydrolase family 16) domain%3B KEGG: ngl:RG1141_CH33510 endo-1%2C3-1%2C4-beta-glycanase ExoK%3B Glycosidases%2C i. e. enzymes hydrolyzing O- and S-glycosyl compounds gene gene4043 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04044 BSBS38_04045 BSBS38_04045 BSBS38_04045 3798049 3798819 - PtsGHI operon antiterminator Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of GlcT directly binds to the RNA antiterminator (RAT) sequence and prevents transcriptional termination. GlcT binding requires two identical and nearly symmetrical triple base pairings in the RAT sequence%3B Belongs to the transcriptional antiterminator BglG family. GlcT subfamily%3B Contains 2 PRD domains gene gene4044 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04045 BSBS38_04046 BSBS38_04046 BSBS38_04046 3798977 3799657 - uncharacterized protein gene gene4045 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04046 BSBS38_04047 BSBS38_04047 BSBS38_04047 3799867 3801150 + putative MFS-type transporter YxiO Belongs to the major facilitator superfamily gene gene4046 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04047 BSBS38_04048 BSBS38_04048 BSBS38_04048 3801169 3802608 - RNA helicase DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity%2C which is specific for 23S rRNA%2C and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes (Probable)%3B Belongs to the DEAD box helicase family. DbpA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: emu:EMQU_1316 ATP-dependent RNA helicase CshB gene gene4047 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04048 BSBS38_04049 BSBS38_04049 BSBS38_04049 3802690 3803838 - putative esterase YxiM Belongs to the 'GDSL' lipolytic enzyme family gene gene4048 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04049 BSBS38_04050 BSBS38_04050 BSBS38_04050 3803968 3804318 - uncharacterized protein gene gene4049 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04050 BSBS38_04051 BSBS38_04051 BSBS38_04051 3804338 3804790 - uncharacterized protein gene gene4050 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04051 BSBS38_04052 BSBS38_04052 BSBS38_04052 3804806 3805102 - uncharacterized protein gene gene4051 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04052 BSBS38_04053 BSBS38_04053 BSBS38_04053 3805120 3805431 - hypothetical protein gene gene4052 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04053 BSBS38_04054 BSBS38_04054 BSBS38_04054 3805458 3805808 - hypothetical protein gene gene4053 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04054 BSBS38_04055 BSBS38_04055 BSBS38_04055 3805975 3806241 - hypothetical protein gene gene4054 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04055 BSBS38_04056 BSBS38_04056 BSBS38_04056 3806181 3806732 - hypothetical protein gene gene4055 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04056 BSBS38_04057 BSBS38_04057 BSBS38_04057 3806758 3807246 - uncharacterized protein gene gene4056 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04057 BSBS38_04058 BSBS38_04058 BSBS38_04058 3807264 3808115 - uncharacterized protein gene gene4057 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04058 BSBS38_04059 BSBS38_04059 BSBS38_04059 3808191 3808577 - uncharacterized protein gene gene4058 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04059 BSBS38_04060 BSBS38_04060 BSBS38_04060 3808624 3809058 - uncharacterized protein gene gene4059 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04060 BSBS38_04061 BSBS38_04061 BSBS38_04061 3809135 3809515 - hypothetical protein gene gene4060 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04061 BSBS38_04062 BSBS38_04062 BSBS38_04062 3809630 3810052 - Immunity protein WapI Immunity protein component of a toxin-immunity protein module%2C which functions as a cellular contact-dependent growth inhibition (CDI) system. Neutralizes the tRNase activity of cognate toxin WapA upon expression in E. coli. Does not inhibit WapA from other strains of B. subtilis. The WapA C-terminus cannot be expressed on its own in E. coli%2C however it can be cloned in the presence of its cognate immunity protein gene. Cell contact is necessary for growth inhibition gene gene4061 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04062 BSBS38_04063 BSBS38_04063 BSBS38_04063 3810197 3810607 - uncharacterized protein gene gene4062 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04063 BSBS38_04064 BSBS38_04064 BSBS38_04064 3810660 3810959 - uncharacterized protein gene gene4063 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04064 BSBS38_04065 BSBS38_04065 BSBS38_04065 3811032 3811502 - uncharacterized protein gene gene4064 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04065 BSBS38_04066 BSBS38_04066 BSBS38_04066 3811643 3812197 - hypothetical protein gene gene4065 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04066 BSBS38_04067 BSBS38_04067 BSBS38_04067 3812190 3813020 - uncharacterized protein gene gene4066 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04067 BSBS38_04068 BSBS38_04068 BSBS38_04068 3813247 3813921 - hypothetical protein gene gene4067 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04068 BSBS38_04069 BSBS38_04069 BSBS38_04069 3814080 3814769 - hypothetical protein gene gene4068 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04069 BSBS38_04070 BSBS38_04070 BSBS38_04070 3814775 3815647 - tRNA(Glu)-specific nuclease WapA Toxic component of a toxin-immunity protein module%2C which functions as a cellular contact-dependent growth inhibition (CDI) system. A site-specific tRNA(Glu) nuclease%2C the C-terminus (residues 2214-2346) probably removes 2 or 4 nucleotides from the 3' end of tRNA(Glu) but not tRNA2(Arg) or tRNA3(Ser) (upon expression in E. coli)%2C possibly endonucleolytically. subtilis strains. The C-terminus cannot be expressed on its own in E. coli%2C however it can be cloned in the presence of its cognate immunity protein gene wapI. Cell contact is probably necessary for growth inhibition%3B Belongs to the RHS/WapA nuclease family%3B Contains 5 YD repeats gene gene4069 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04070 BSBS38_04071 BSBS38_04071 BSBS38_04071 3815754 3816113 - Immunity protein WapI Immunity protein component of a toxin-immunity protein module%2C which functions as a cellular contact-dependent growth inhibition (CDI) system. Neutralizes the tRNase activity of cognate toxin WapA upon expression in E. coli. Does not inhibit WapA from other strains of B. subtilis. The WapA C-terminus cannot be expressed on its own in E. coli%2C however it can be cloned in the presence of its cognate immunity protein gene. Cell contact is probably necessary for growth inhibition gene gene4070 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04071 BSBS38_04072 BSBS38_04072 BSBS38_04072 3816150 3823154 - tRNA(Glu)-specific nuclease WapA Toxic component of a toxin-immunity protein module%2C which functions as a cellular contact-dependent growth inhibition (CDI) system. A site-specific tRNA(Glu) nuclease%2C the C-terminus (residues 2214-2346) probably removes 2 or 4 nucleotides from the 3' end of tRNA(Glu) but not tRNA2(Arg) or tRNA3(Ser) (upon expression in E. coli)%2C possibly endonucleolytically. subtilis strains. The C-terminus cannot be expressed on its own in E. coli%2C however it can be cloned in the presence of its cognate immunity protein gene wapI. Cell contact is probably necessary for growth inhibition%3B Belongs to the RHS/WapA nuclease family%3B Contains 5 YD repeats gene gene4071 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04072 BSBS38_04073 BSBS38_04073 BSBS38_04073 3823319 3824257 - putative transporter YxxF Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene4072 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04073 BSBS38_04074 BSBS38_04074 BSBS38_04074 3824321 3825064 - 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sai:Saci_0238 3-oxoacyl-(acyl-carrier protein) reductase gene gene4073 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04074 BSBS38_04075 BSBS38_04075 BSBS38_04075 3825232 3825963 + L-isoleucine-4-hydroxylase Catalyzes the hydroxylation of L-isoleucine to produce (4S)-4-hydroxy-L-isoleucine (PubMed:20665018%2C PubMed:19850012%2C PubMed:21821743). Can also catalyze the hydroxylation of L- leucine%2C L-norvaline%2C L-norleucine and L-allo-isoleucine%2C as well as the sulfoxidation of L-methionine%2C L-ethionine%2C S-methyl-L- cysteine%2C S-ethyl-L-cysteine%2C and S-allyl-L-cysteine (PubMed:21821743)%3B Belongs to the iron/ascorbate-dependent oxidoreductase family gene gene4074 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04075 BSBS38_04076 BSBS38_04076 BSBS38_04076 3825997 3826443 - Universal stress protein YxiE Belongs to the universal stress protein A family gene gene4075 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04076 BSBS38_04077 BSBS38_04077 BSBS38_04077 3826546 3827445 - 6-phospho-beta-glucosidase Can hydrolyze salicin%2C cellobiose%2C and probably arbutin. Belongs to the glycosyl hydrolase 1 family%3B KEGG: eco:b2716 6-phospho-beta-glucosidase%3B overlaps another CDS with the same product name gene gene4076 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04077 BSBS38_04078 BSBS38_04078 BSBS38_04078 3827435 3827821 - 6-phospho-beta-glucosidase Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bsu:BSU39260 6-phospho-beta-glucosidase%3B overlaps another CDS with the same product name gene gene4077 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04078 BSBS38_04079 BSBS38_04079 BSBS38_04079 3828128 3828367 - uncharacterized protein gene gene4078 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04079 BSBS38_04080 BSBS38_04080 BSBS38_04080 3828413 3828856 - Antitoxin YxxD Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the RNase activity of cognate toxin YxiD%2C as well as its ability to inhibit growth upon expression in E. coli. Does not have antitoxin activity on other toxins with the LXG toxin domain gene gene4079 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04080 BSBS38_04081 BSBS38_04081 BSBS38_04081 3828853 3830358 - Ribonuclease YxiD Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene4080 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04081 BSBS38_04082 BSBS38_04082 BSBS38_04082 3830689 3831015 - hypothetical protein gene gene4081 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04082 BSBS38_04083 BSBS38_04083 BSBS38_04083 3831032 3832648 - Ribonuclease YxiD Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene4082 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04083 BSBS38_04084 BSBS38_04084 BSBS38_04084 3832668 3832937 - uncharacterized protein gene gene4083 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04084 BSBS38_04085 BSBS38_04085 BSBS38_04085 3832949 3833314 - uncharacterized protein gene gene4084 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04085 BSBS38_04086 BSBS38_04086 BSBS38_04086 3833636 3834067 - HpaII very short patch repair endonuclease May nick HpaII sequences that contain T:G mispairs resulting from m5C-deamination. Belongs to the vsr family%3B KEGG: bao:BAMF_3750 DNA mismatch endonuclease%2C patch repair protein%3B Acting on ester bonds gene gene4085 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04086 BSBS38_04087 BSBS38_04087 BSBS38_04087 3834221 3835327 + DNA (cytosine-5-)-methyltransferase This methylase recognizes the double-stranded sequence GCWGC%2C causes specific methylation on C-2 on both strands%2C and protects the DNA from cleavage by the BbvI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bamf:U722_19415 DNA (cytosine-5)-methyltransferase 1 gene gene4086 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04087 BSBS38_04088 BSBS38_04088 BSBS38_04088 3835411 3837411 - hypothetical protein gene gene4087 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04088 BSBS38_04089 BSBS38_04089 BSBS38_04089 3837423 3838298 - hypothetical protein gene gene4088 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04089 BSBS38_04090 BSBS38_04090 BSBS38_04090 3838506 3839726 - Arabinan endo-1%2C5-alpha-L-arabinosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of the alpha-1%2C5-L-arabinan to produce arabino- oligosaccharides and L-arabinose. It is also active toward linear branched sugar beet arabinan%2C and pectin from apple%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bsu:BSU39330 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene4089 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04090 BSBS38_04091 BSBS38_04091 hutU hutU 3839869 3841275 + Urocanate hydratase Belongs to the urocanase family%3B KEGG: bso:BSNT_06039 urocanate hydratase gene gene4090 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04091 BSBS38_04092 BSBS38_04092 hutI hutI 3841288 3842553 + Imidazolonepropionase Belongs to the HutI family%3B KEGG: bsu:BSU39370 imidazolonepropionase gene gene4091 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04092 BSBS38_04093 BSBS38_04093 hutG hutG 3842546 3843505 + Formimidoylglutamase Belongs to the arginase family%3B KEGG: bsu:BSU39380 formiminoglutamase gene gene4092 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04093 BSBS38_04094 BSBS38_04094 BSBS38_04094 3843644 3845008 + Putative histidine permease Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene4093 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04094 BSBS38_04095 BSBS38_04095 BSBS38_04095 3845051 3846352 - Pyrimidine-nucleoside phosphorylase Catalyzes phosphorolysis of the pyrimidine nucleosides uridine%2C thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate%3B Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family%3B KEGG: bsu:BSU39400 pyrimidine-nucleoside phosphorylase gene gene4094 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04095 BSBS38_04096 BSBS38_04096 BSBS38_04096 3846382 3847563 - Pyrimidine nucleoside transport protein Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene4095 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04096 BSBS38_04097 BSBS38_04097 deoC deoC 3847644 3848315 - Deoxyribose-phosphate aldolase Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate%3B Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily%3B KEGG: bsu:BSU39420 deoxyribose-phosphate aldolase gene gene4096 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04097 BSBS38_04098 BSBS38_04098 BSBS38_04098 3848420 3849361 - Deoxyribonucleoside regulator Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA%2C which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family gene gene4097 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04098 BSBS38_04099 BSBS38_04099 BSBS38_04099 3849495 3850322 - uncharacterized protein gene gene4098 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04099 BSBS38_04100 BSBS38_04100 BSBS38_04100 3850395 3851507 - uncharacterized protein Belongs to the EutH family gene gene4099 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04100 BSBS38_04101 BSBS38_04101 irg1 irg1 3851578 3852915 - Aconitate decarboxylase Belongs to the PrpD family%3B KEGG: pno:SNOG_15138 aconitate decarboxylase gene gene4100 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04101 BSBS38_04102 BSBS38_04102 BSBS38_04102 3852912 3854054 - putative hydrolase YxeP Belongs to the peptidase M20 family%3B KEGG: bsu:BSU39470 amidohydrolase%3B In linear amides gene gene4101 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04102 BSBS38_04103 BSBS38_04103 BSBS38_04103 3854071 3854820 - Energy-dependent translational throttle protein EttA A translation factor that gates the progression of the 70S ribosomal inititation complex (IC%2C containing tRNA(fMet) in the P site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E site where it modulates the state of the translating ribosome during subunit translocation (By similarity)%3B Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily%3B Contains 2 ABC transporter domains gene gene4102 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04103 BSBS38_04104 BSBS38_04104 BSBS38_04104 3854833 3855507 - putative amino-acid permease protein YxeN Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene4103 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04104 BSBS38_04105 BSBS38_04105 BSBS38_04105 3855530 3856324 - putative amino-acid-binding protein YxeM Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Belongs to the bacterial solute-binding protein 3 family gene gene4104 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04105 BSBS38_04106 BSBS38_04106 BSBS38_04106 3856349 3856846 - putative N-acetyltransferase YxeL Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene4105 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04106 BSBS38_04107 BSBS38_04107 BSBS38_04107 3856860 3858185 - Alkanesulfonate monooxygenase Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family%3B KEGG: ava:Ava_1266 alkanesulfonate monooxygenase gene gene4106 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04107 BSBS38_04108 BSBS38_04108 BSBS38_04108 3858617 3859603 - Choloylglycine hydrolase Belongs to the peptidase C59 family%3B KEGG: bsu:BSU39540 choloylglycine hydrolase gene gene4107 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04108 BSBS38_04109 BSBS38_04109 BSBS38_04109 3859758 3860570 - Putative phosphatase Belongs to the HAD-like hydrolase superfamily. Cof family gene gene4108 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04109 BSBS38_04110 BSBS38_04110 BSBS38_04110 3860610 3861167 - uncharacterized protein overlaps another CDS with the same product name gene gene4109 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04110 BSBS38_04111 BSBS38_04111 BSBS38_04111 3861148 3861582 - uncharacterized protein overlaps another CDS with the same product name gene gene4110 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04111 BSBS38_04112 BSBS38_04112 BSBS38_04112 3861671 3862036 + uncharacterized protein gene gene4111 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04112 BSBS38_04113 BSBS38_04113 BSBS38_04113 3862284 3862637 + Non-specific serine/threonine protein kinase KEGG: shr:100929955 mitogen-activated protein kinase kinase kinase kinase 4 gene gene4112 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04113 BSBS38_04114 BSBS38_04114 BSBS38_04114 3862681 3863079 - uncharacterized protein gene gene4113 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04114 BSBS38_04115 BSBS38_04115 BSBS38_04115 3863193 3864113 + Iron(3+)-hydroxamate-binding protein YxeB Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene4114 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04115 BSBS38_04116 BSBS38_04116 BSBS38_04116 3864154 3864501 - uncharacterized protein gene gene4115 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04116 BSBS38_04117 BSBS38_04117 BSBS38_04117 3864515 3866383 - ABC transporter permease protein YxdM Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Belongs to the ABC-4 integral membrane protein family gene gene4116 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04117 BSBS38_04118 BSBS38_04118 lolD lolD 3866358 3867131 - Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: pub:SAR11_0905 lipoprotein-releasing system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene4117 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04118 BSBS38_04119 BSBS38_04119 yxdK yxdK 3867275 3868252 - Histidine kinase Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU39650 two-component system%2C OmpR family%2C sensor histidine kinase YxdK gene gene4118 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04119 BSBS38_04120 BSBS38_04120 BSBS38_04120 3868249 3868479 - Transcriptional regulatory protein YxdJ Probable member of the two-component regulatory system YxdK/YxdJ. Positively regulates the expression of the yxdLMyxeA operon by direct interaction with its promoter region. Could also indirectly regulate the expression of the dlt operon%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4119 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04120 BSBS38_04121 BSBS38_04121 BSBS38_04121 3868419 3868823 - Response regulator ArlR Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4120 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04121 BSBS38_04122 BSBS38_04122 BSBS38_04122 3868931 3869803 - Fructose-bisphosphate aldolase Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the class II fructose-bisphosphate aldolase family. IolJ subfamily%3B KEGG: pna:Pnap_1988 fructose-bisphosphate aldolase%2C class II gene gene4121 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04122 BSBS38_04123 BSBS38_04123 iolI iolI 3869824 3870660 - 2-keto-myo-inositol isomerase Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI%2C inosose or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2%2C3%2C5/4%2C6- pentahydroxycyclohexanone)%3B Belongs to the IolI family%3B KEGG: bsu:BSU39680 2-keto-myo-inositol isomerase gene gene4122 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04123 BSBS38_04124 BSBS38_04124 BSBS38_04124 3870746 3871615 - Protein IolH gene gene4123 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04124 BSBS38_04125 BSBS38_04125 BSBS38_04125 3871635 3872669 - Inositol 2-dehydrogenase Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: eta:ETA_32880 myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase gene gene4124 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04125 BSBS38_04126 BSBS38_04126 BSBS38_04126 3872692 3874023 - Minor myo-inositol transporter IolF Minor myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene4125 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04126 BSBS38_04127 BSBS38_04127 BSBS38_04127 3874023 3874916 - Myo-inosose-2 dehydratase Catalyzes the dehydration of inosose (2-keto-myo- inositol%2C 2KMI or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (D-2%2C3-diketo-4-deoxy-epi- inositol)%3B Belongs to the IolE/MocC family%3B KEGG: bsu:BSU39720 inosose dehydratase gene gene4126 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04127 BSBS38_04128 BSBS38_04128 iolD iolD 3874932 3876845 - 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) Involved in the cleavage of the C1-C2 bond of 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)%3B Belongs to the TPP enzyme family%3B KEGG: bsu:BSU39730 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) gene gene4127 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04128 BSBS38_04129 BSBS38_04129 iolC iolC 3876878 3877855 - 5-dehydro-2-deoxygluconokinase Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU39740 5-dehydro-2-deoxygluconokinase gene gene4128 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04129 BSBS38_04130 BSBS38_04130 iolB iolB 3877879 3878694 - 5-deoxy-glucuronate isomerase Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)%3B Belongs to the isomerase IolB family%3B KEGG: bsu:BSU39750 5-deoxy-glucuronate isomerase gene gene4129 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04130 BSBS38_04131 BSBS38_04131 doeC doeC 3878769 3880232 - Methylmalonate semialdehyde dehydrogenase (acylating) Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA%2C respectively%3B Belongs to the aldehyde dehydrogenase family. IolA subfamily%3B KEGG: vej:VEJY3_17211 aspartate-semialdehyde dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene4130 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04131 BSBS38_04132 BSBS38_04132 BSBS38_04132 3880649 3881404 + HTH-type transcriptional regulator IolR Iol operon repressor. Contains 1 HTH deoR-type DNA-binding domain gene gene4131 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04132 BSBS38_04133 BSBS38_04133 BSBS38_04133 3881458 3882390 + Protein IolS Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: bsu:BSU39780 myo-inositol catabolism protein IolS%3B With NAD(+) or NADP(+) as acceptor gene gene4132 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04133 BSBS38_04134 BSBS38_04134 BSBS38_04134 3882650 3883300 + uncharacterized protein gene gene4133 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04134 BSBS38_04135 BSBS38_04135 BSBS38_04135 3883304 3883612 + uncharacterized protein gene gene4134 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04135 BSBS38_04136 BSBS38_04136 BSBS38_04136 3883854 3885239 + putative metabolite transport protein CsbC Could serve either a nutritional or an osmotic protection function. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene4135 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04136 BSBS38_04137 BSBS38_04137 BSBS38_04137 3885281 3887161 - Chaperone protein HtpG Molecular chaperone. Has ATPase activity%3B Belongs to the heat shock protein 90 family gene gene4136 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04137 BSBS38_04138 BSBS38_04138 BSBS38_04138 3887329 3887580 - uncharacterized protein gene gene4137 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04138 BSBS38_04139 BSBS38_04139 BSBS38_04139 3887697 3887897 + D-sorbitol dehydrogenase (acceptor) Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ara:Arad_12179 D-sorbitol dehydrogenase (acceptor) gene gene4138 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04139 BSBS38_04140 BSBS38_04140 BSBS38_04140 3888122 3888517 + putative oxidoreductase YxbG Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU39840 null%3B Oxidoreductases gene gene4139 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04140 BSBS38_04141 BSBS38_04141 BSBS38_04141 3888668 3888892 - hypothetical protein gene gene4140 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04141 BSBS38_04142 BSBS38_04142 BSBS38_04142 3888909 3889139 - hypothetical protein gene gene4141 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04142 BSBS38_04143 BSBS38_04143 BSBS38_04143 3889324 3889749 - hypothetical protein gene gene4142 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04143 BSBS38_04144 BSBS38_04144 BSBS38_04144 3889739 3889957 - putative HTH-type transcriptional regulator Contains 1 HTH cro/C1-type DNA-binding domain gene gene4143 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04144 BSBS38_04145 BSBS38_04145 BSBS38_04145 3890101 3890253 + hypothetical protein gene gene4144 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04145 BSBS38_04146 BSBS38_04146 BSBS38_04146 3890367 3892550 + Mesentericin-Y105 transport/processing ATP-binding protein MesD Involved in the export process of the bacteriocin mesentericin-Y105. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene4145 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04146 BSBS38_04147 BSBS38_04147 BSBS38_04147 3892551 3894020 + Mesentericin Y105 secretion protein MesE Involved in the secretion of mesentericin Y105. Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene4146 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04147 BSBS38_04148 BSBS38_04148 BSBS38_04148 3894120 3894308 + hypothetical protein gene gene4147 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04148 BSBS38_04149 BSBS38_04149 BSBS38_04149 3894341 3895483 - putative HTH-type transcriptional regulator YxbF Contains 2 HTH tetR-type DNA-binding domains gene gene4148 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04149 BSBS38_04150 BSBS38_04150 BSBS38_04150 3895624 3896961 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU39860 aldehyde dehydrogenase (NAD+) gene gene4149 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04150 BSBS38_04151 BSBS38_04151 BSBS38_04151 3897167 3897634 + uncharacterized protein gene gene4150 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04151 BSBS38_04152 BSBS38_04152 BSBS38_04152 3897783 3898208 - uncharacterized protein gene gene4151 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04152 BSBS38_04153 BSBS38_04153 BSBS38_04153 3898464 3898919 + Non-specific serine/threonine protein kinase KEGG: calt:Cal6303_0729 serine/threonine protein kinase%2C bacterial gene gene4152 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04153 BSBS38_04154 BSBS38_04154 BSBS38_04154 3898949 3900157 - uncharacterized protein Involved in transport gene gene4153 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04154 BSBS38_04155 BSBS38_04155 qodI qodI 3900265 3901278 - Quercetin 2%2C3-dioxygenase Performs the first step in the degradation of the flavonoid quercetin by a dioxygenase reaction. The enzyme catalyzes the cleavage of the O-heteroaromatic ring of the flavonol quercetin yielding the depside 2-protocatechuoyl- phloroglucinol carboxylic acid and carbon monoxide. This involves the remarkable dioxygenolytic cleavage of two carbon-carbon bonds%3B KEGG: bsu:BSU39980 quercetin 2%2C3-dioxygenase gene gene4154 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04155 BSBS38_04156 BSBS38_04156 BSBS38_04156 3901372 3901947 - putative HTH-type transcriptional regulator YxaF Contains 1 HTH tetR-type DNA-binding domain gene gene4155 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04156 BSBS38_04157 BSBS38_04157 BSBS38_04157 3902078 3903148 + putative oxidoreductase YxnA Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: acc:BDGL_001065 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene4156 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04157 BSBS38_04158 BSBS38_04158 BSBS38_04158 3903207 3903638 - putative HTH-type transcriptional regulator YxaD Contains 1 HTH marR-type DNA-binding domain gene gene4157 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04158 BSBS38_04159 BSBS38_04159 BSBS38_04159 3903865 3904269 + Putative integral membrane protein YxzK gene gene4158 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04159 BSBS38_04160 BSBS38_04160 BSBS38_04160 3904239 3904931 + uncharacterized protein Belongs to the YohK (E. coli)/YwbG (IPA-22R) (B. subtilis) family gene gene4159 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04160 BSBS38_04161 BSBS38_04161 BSBS38_04161 3904971 3906002 - General stress protein Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: beo:BEH_02040 pyruvyl transferase EpsI%3B Transferases gene gene4160 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04161 BSBS38_04162 BSBS38_04162 glxK glxK 3906072 3906695 - Glycerate 3-kinase Belongs to the glycerate kinase type-1 family%3B KEGG: vvu:VV1_1654 glycerate kinase gene gene4161 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04162 BSBS38_04163 BSBS38_04163 BSBS38_04163 3906719 3907240 - Glycerate 3-kinase Belongs to the glycerate kinase type-1 family%3B KEGG: eco:b0514 glycerate kinase gene gene4162 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04163 BSBS38_04164 BSBS38_04164 BSBS38_04164 3907436 3908167 + Gluconate operon transcriptional repressor Transcriptional repressor of the gluconate operon (gntRKPZ)%2C which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operato%3B the binding is suppressed by gluconate or glucono-delta-lactone. Contains 1 HTH gntR-type DNA-binding domain gene gene4163 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04164 BSBS38_04165 BSBS38_04165 gntK gntK 3908160 3909701 + Gluconokinase Belongs to the FGGY kinase family%3B KEGG: bsu:BSU40060 gluconokinase gene gene4164 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04165 BSBS38_04166 BSBS38_04166 BSBS38_04166 3909730 3911076 + Gluconate permease Belongs to the GntP permease family gene gene4165 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04166 BSBS38_04167 BSBS38_04167 BSBS38_04167 3911099 3912505 + Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NAD to NADH. Does not contribute to oxidative pentose phosphate (PP) pathway fluxes during growth on glucose. The functional role of GntZ remains obscure%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: bsu:BSU40080 6-phosphogluconate dehydrogenase gene gene4166 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04167 BSBS38_04168 BSBS38_04168 BSBS38_04168 3912995 3913558 + Peroxiredoxin Directly reduces organic hydroperoxides in its reduced dithiol form. Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: ssan:NX02_24280 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene4167 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04168 BSBS38_04169 BSBS38_04169 ahpF ahpF 3913572 3915101 + NADH dehydrogenase Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: bsu:BSU40100 alkyl hydroperoxide reductase subunit F%3B With a disulfide as acceptor gene gene4168 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04169 BSBS38_04170 BSBS38_04170 BSBS38_04170 3915213 3916652 - 6-phospho-beta-glucosidase Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: eca:ECA4432 6-phospho-beta-glucosidase gene gene4169 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04170 BSBS38_04171 BSBS38_04171 BSBS38_04171 3916936 3917067 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase KEGG: bsr:I33_4177 PTS system%2C beta-glucosides-specific IIA component gene gene4170 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04171 BSBS38_04172 BSBS38_04172 BSBS38_04172 3917220 3917930 + putative HTH-type transcriptional regulator YydK Contains 1 HTH gntR-type DNA-binding domain gene gene4171 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04172 BSBS38_04173 BSBS38_04173 BSBS38_04173 3917956 3918114 + putative membrane protein YyzN gene gene4172 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04173 BSBS38_04174 BSBS38_04174 BSBS38_04174 3918245 3918967 - putative peptide export permease protein YydJ Suggested to be part of an ABC transporter complex YydIJ involved in export of the modified peptide YydF gene gene4173 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04174 BSBS38_04175 BSBS38_04175 BSBS38_04175 3918988 3919617 - putative peptide export ATP-binding protein YydI Suggested to be part of an ABC transporter complex YydIJ involved in export of the modified peptide YydF (Probable). Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4174 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04175 BSBS38_04176 BSBS38_04176 fbp3 fbp3 3920098 3922023 + Fructose-bisphosphatase Belongs to the FBPase class 3 family%3B KEGG: bsu:BSU40190 fructose-1%2C6-bisphosphatase III gene gene4175 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04176 BSBS38_04177 BSBS38_04177 BSBS38_04177 3922996 3923232 - hypothetical protein gene gene4176 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04177 BSBS38_04178 BSBS38_04178 BSBS38_04178 3923305 3923745 + Small heat shock protein C4 Belongs to the small heat shock protein (HSP20) family gene gene4177 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04178 BSBS38_04179 BSBS38_04179 BSBS38_04179 3923997 3924125 + N-acetylmuramoyl-L-alanine amidase Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination%3B Belongs to the CwlJ family%3B KEGG: bso:BSNT_06158 N-acetylmuramoyl-L-alanine amidase gene gene4178 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04179 BSBS38_04180 BSBS38_04180 BSBS38_04180 3924165 3924923 - Insertion sequence IS21 putative ATP-binding protein One of two proteins expressed only when there is a tandem repeat of the IS21 insertion sequence%2C it is necessary for the transposition of plasmids with that tandem repeat. Belongs to the IS21/IS1162 putative ATP-binding protein family gene gene4179 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04180 BSBS38_04181 BSBS38_04181 BSBS38_04181 3924920 3926467 - Transposase for insertion sequence element IS21-like protein Involved in the transposition of the insertion sequence%3B Belongs to the transposase IS21/IS408/IS1162 family%3B Contains 1 HTH IS21-type DNA-binding domain%3B Contains 1 integrase catalytic domain gene gene4180 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04181 BSBS38_04182 BSBS38_04182 BSBS38_04182 3926597 3927010 - hypothetical protein gene gene4181 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04182 BSBS38_04183 BSBS38_04183 BSBS38_04183 3927395 3928858 + hypothetical protein gene gene4182 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04183 BSBS38_04184 BSBS38_04184 BSBS38_04184 3929248 3931131 - DNA helicase KEGG: ssz:SCc_686 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene4183 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04184 BSBS38_04185 BSBS38_04185 BSBS38_04185 3931112 3933145 - hypothetical protein gene gene4184 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04185 BSBS38_04186 BSBS38_04186 BSBS38_04186 3933662 3934030 - putative transposase for insertion sequence element IS1353 Probably involved in the transposition of insertion sequence IS1353. Belongs to the transposase 8 family%3B Contains 1 integrase catalytic domain gene gene4185 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04186 BSBS38_04187 BSBS38_04187 BSBS38_04187 3934203 3934520 + hypothetical protein gene gene4186 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04187 BSBS38_04188 BSBS38_04188 BSBS38_04188 3934852 3935430 + Insertion element IS476 uncharacterized 39.2 kDa protein Contains 1 integrase catalytic domain gene gene4187 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04188 BSBS38_04189 BSBS38_04189 rlmH rlmH 3935536 3936015 - 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA%3B Belongs to the RNA methyltransferase RlmH family%3B KEGG: bsu:BSU40230 23S rRNA (pseudouridine1915-N3)-methyltransferase gene gene4188 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04189 BSBS38_04190 BSBS38_04190 BSBS38_04190 3936096 3936266 - uncharacterized protein gene gene4189 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04190 BSBS38_04191 BSBS38_04191 BSBS38_04191 3936451 3936864 + uncharacterized protein gene gene4190 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04191 BSBS38_04192 BSBS38_04192 fdhA fdhA 3936898 3938109 - Formaldehyde dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU40250 glutathione-independent formaldehyde dehydrogenase gene gene4191 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04192 BSBS38_04193 BSBS38_04193 BSBS38_04193 3938187 3938357 - putative membrane protein YyzG gene gene4192 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04193 BSBS38_04194 BSBS38_04194 BSBS38_04194 3938615 3938710 - uncharacterized protein gene gene4193 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04194 BSBS38_04195 BSBS38_04195 BSBS38_04195 3938726 3939889 - uncharacterized protein gene gene4194 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04195 BSBS38_04196 BSBS38_04196 BSBS38_04196 3939900 3940637 - uncharacterized protein gene gene4195 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04196 BSBS38_04197 BSBS38_04197 BSBS38_04197 3940779 3941249 - putative N-acetyltransferase YycN Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene4196 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04197 BSBS38_04198 BSBS38_04198 rapG rapG 3941360 3942457 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU40300 response regulator aspartate phosphatase G%3B Acting on ester bonds gene gene4197 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04198 BSBS38_04199 BSBS38_04199 BSBS38_04199 3942458 3942574 + Phosphatase RapG inhibitor Inhibitor of the activity of phosphatase RapG. Belongs to the phr family gene gene4198 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04199 BSBS38_04200 BSBS38_04200 rocF rocF 3942811 3943701 - Arginase Involved in the catabolism of arginine%3B Belongs to the arginase family%3B KEGG: bsu:BSU40320 arginase gene gene4199 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04200 BSBS38_04201 BSBS38_04201 BSBS38_04201 3943774 3945177 - Amino-acid permease RocE Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene4200 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04201 BSBS38_04202 BSBS38_04202 rocD rocD 3945400 3946605 - Ornithine aminotransferase Catalyzes the interconversion of ornithine to glutamate semialdehyde. Controls arginine catabolism%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily%3B KEGG: bsu:BSU40340 ornithine--oxo-acid transaminase gene gene4201 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04202 BSBS38_04203 BSBS38_04203 BSBS38_04203 3946937 3947539 - Killing factor SdpC Induces the lysis of other B. subtilis cells that have not entered the sporulation pathway%2C providing a source of nutrients to support sporulation. Its maturation is dependent on SdpA and SdpB. Also functions as a ligand%2C being able to bind to SdpI thereby triggering a signal transduction cascade that protects the cell against the toxic effects of its own SdpC gene gene4202 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04203 BSBS38_04204 BSBS38_04204 BSBS38_04204 3947601 3948554 - uncharacterized protein gene gene4203 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04204 BSBS38_04205 BSBS38_04205 BSBS38_04205 3948539 3948856 - hypothetical protein gene gene4204 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04205 BSBS38_04206 BSBS38_04206 BSBS38_04206 3949277 3949915 - Immunity protein SdpI Immunity protein that provides protection for the cell against the toxic effects of its own SdpC killing factor%2C and that functions as a receptor/signal transduction protein as well. Once SdpC accumulates in the extracellular milieu%2C SdpI binds to SdpC%2C causing sequestration of SdpR at the bacterial membrane gene gene4205 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04206 BSBS38_04207 BSBS38_04207 BSBS38_04207 3949912 3950196 - Transcriptional repressor SdpR Represses the transcription of the sdpIR operon and of several other operons that probably contribute to delaying commitment to sporulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene4206 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04207 BSBS38_04208 BSBS38_04208 BSBS38_04208 3950422 3951807 + Arginine utilization regulatory protein RocR Positive regulator of arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF and probably acts by binding to the corresponding upstream activating sequences%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 sigma-54 factor interaction domain gene gene4207 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04208 BSBS38_04209 BSBS38_04209 BSBS38_04209 3952122 3953324 - Peptidase Do Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bso:BSNT_06195 serine protease Do gene gene4208 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04209 BSBS38_04210 BSBS38_04210 BSBS38_04210 3953406 3954200 - Putative metallo-hydrolase YycJ Belongs to the metallo-beta-lactamase superfamily gene gene4209 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04210 BSBS38_04211 BSBS38_04211 BSBS38_04211 3954222 3955064 - Two-component system YycFG regulatory protein Together with YycH%2C regulates the activity of the two- component system YycF/YycG gene gene4210 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04211 BSBS38_04212 BSBS38_04212 BSBS38_04212 3955051 3956427 - Two-component system YycF/YycG regulatory protein YycH Together with YycI%2C regulates the activity of the two- component system YycF/YycG gene gene4211 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04212 BSBS38_04213 BSBS38_04213 BSBS38_04213 3956408 3958243 - Histidine kinase Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon%2C the yocH and ykvT%2C cwlO%2C lytE%2C ydjM%2C yjeA%2C yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU40400 two-component system%2C OmpR family%2C sensor histidine kinase VicK gene gene4212 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04213 BSBS38_04214 BSBS38_04214 BSBS38_04214 3958251 3958961 - Phosphate regulon transcriptional regulatory protein This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4213 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04214 BSBS38_04215 BSBS38_04215 BSBS38_04215 3959343 3959415 - tRNA-Phe tRNA gene4214 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04215 BSBS38_04216 BSBS38_04216 BSBS38_04216 3959451 3959527 - tRNA-Asp tRNA gene4215 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04216 BSBS38_04217 BSBS38_04217 BSBS38_04217 3959609 3959680 - tRNA-Glu tRNA gene4216 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04217 BSBS38_04218 BSBS38_04218 BSBS38_04218 3959690 3959765 - tRNA-Lys tRNA gene4217 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04218 BSBS38_04219 BSBS38_04219 purA purA 3959989 3961281 - Adenylosuccinate synthase Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP%3B Belongs to the adenylosuccinate synthetase family%3B KEGG: vvu:VV2_0768 adenylosuccinate synthase gene gene4218 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04219 BSBS38_04220 BSBS38_04220 preP preP 3961487 3961906 - Prolyl oligopeptidase KEGG: vfi:VF_A0660 prolyl oligopeptidase gene gene4219 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04220 BSBS38_04221 BSBS38_04221 dnaB dnaB 3962026 3963390 - DNA helicase Belongs to the helicase family. DnaB subfamily%3B Contains 1 SF4 helicase domain%3B KEGG: bsu:BSU40440 replicative DNA helicase gene gene4220 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04221 BSBS38_04222 BSBS38_04222 BSBS38_04222 3963560 3963760 + uncharacterized protein gene gene4221 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04222 BSBS38_04223 BSBS38_04223 BSBS38_04223 3963808 3964011 - uncharacterized protein gene gene4222 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04223 BSBS38_04224 BSBS38_04224 BSBS38_04224 3964132 3964272 + uncharacterized protein gene gene4223 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04224 BSBS38_04225 BSBS38_04225 BSBS38_04225 3964345 3965553 + putative transporter YycB Belongs to the major facilitator superfamily. Cyanate porter (TC 2. A. 1. 17) family gene gene4224 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04225 BSBS38_04226 BSBS38_04226 BSBS38_04226 3965659 3967716 + Putative mannosyltransferase YycA Belongs to the glycosyltransferase 39 family gene gene4225 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04226 BSBS38_04227 BSBS38_04227 BSBS38_04227 3967753 3968202 - 50S ribosomal protein L9 Binds to the 23S rRNA%3B Belongs to the ribosomal protein L9P family gene gene4226 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04227 BSBS38_04228 BSBS38_04228 BSBS38_04228 3968199 3970178 - uncharacterized protein Contains 1 GGDEF domain gene gene4227 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04228 BSBS38_04229 BSBS38_04229 BSBS38_04229 3970388 3971044 - uncharacterized protein gene gene4228 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04229 BSBS38_04230 BSBS38_04230 BSBS38_04230 3971269 3971418 - putative membrane protein YyzH gene gene4229 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04230 BSBS38_04231 BSBS38_04231 BSBS38_04231 3971564 3971683 + Spore coat protein Belongs to the CotF family gene gene4230 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04231 BSBS38_04232 BSBS38_04232 BSBS38_04232 3971729 3972046 + Spore coat protein Belongs to the CotF family gene gene4231 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04232 BSBS38_04233 BSBS38_04233 BSBS38_04233 3972078 3972455 - putative HTH-type transcriptional regulator YybR Contains 1 HTH hxlR-type DNA-binding domain gene gene4232 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04233 BSBS38_04234 BSBS38_04234 ppaC ppaC 3972661 3973590 + Inorganic diphosphatase Belongs to the PPase class C family%3B KEGG: bsu:BSU40550 manganese-dependent inorganic pyrophosphatase gene gene4233 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04234 BSBS38_04235 BSBS38_04235 BSBS38_04235 3973623 3974069 - putative lipoprotein YybP gene gene4234 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04235 BSBS38_04236 BSBS38_04236 BSBS38_04236 3974081 3974401 - hypothetical protein gene gene4235 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04236 BSBS38_04237 BSBS38_04237 BSBS38_04237 3974502 3975812 + putative transporter YybO Belongs to the major facilitator superfamily. Phthalate permease family gene gene4236 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04237 BSBS38_04238 BSBS38_04238 BSBS38_04238 3975973 3976707 + HTH-type transcriptional activator TipA Transcriptional activator. Is activated when bound to the antibiotic thiostrepton (By similarity)%3B Contains 1 HTH merR-type DNA-binding domain gene gene4237 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04238 BSBS38_04239 BSBS38_04239 BSBS38_04239 3976745 3977533 - uncharacterized protein gene gene4238 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04239 BSBS38_04240 BSBS38_04240 BSBS38_04240 3977601 3977987 - uncharacterized protein gene gene4239 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04240 BSBS38_04241 BSBS38_04241 BSBS38_04241 3978133 3978417 + uncharacterized protein gene gene4240 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04241 BSBS38_04242 BSBS38_04242 BSBS38_04242 3978453 3979052 - putative MFS-type transporter YybF Belongs to the major facilitator superfamily gene gene4241 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04242 BSBS38_04243 BSBS38_04243 BSBS38_04243 3979135 3979527 - putative metallo-hydrolase YybB Belongs to the metallo-beta-lactamase superfamily gene gene4242 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04243 BSBS38_04244 BSBS38_04244 BSBS38_04244 3979657 3980109 - putative HTH-type transcriptional regulator YybA Contains 1 HTH marR-type DNA-binding domain gene gene4243 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04244 BSBS38_04245 BSBS38_04245 BSBS38_04245 3980229 3980669 + Putative acetyltransferase Could catalyze the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and release both CoA and the acetylated product%3B Belongs to the UPF0039 (ElaA) family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK2522 null%3B Transferring groups other than amino-acyl groups gene gene4244 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04245 BSBS38_04246 BSBS38_04246 BSBS38_04246 3980671 3981273 + uncharacterized protein gene gene4245 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04246 BSBS38_04247 BSBS38_04247 BSBS38_04247 3981341 3981862 - uncharacterized protein Contains 1 N-acetyltransferase domain%3B KEGG: ccc:G157_08930 streptothricin acetyltransferase%3B Acyltransferases gene gene4246 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04247 BSBS38_04248 BSBS38_04248 BSBS38_04248 3982271 3982627 + uncharacterized protein gene gene4247 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04248 BSBS38_04249 BSBS38_04249 BSBS38_04249 3982787 3983353 + Dihydrofolate reductase To B. subtilis YwjB%3B KEGG: chu:CHU_2917 dihydrofolate reductase gene gene4248 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04249 BSBS38_04250 BSBS38_04250 BSBS38_04250 3983864 3985240 - Tetracycline resistance protein Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. Belongs to the major facilitator superfamily. TCR/Tet family gene gene4249 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04250 BSBS38_04251 BSBS38_04251 BSBS38_04251 3985590 3987659 + uncharacterized protein To C. elegans B0495. 5 gene gene4250 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04251 BSBS38_04252 BSBS38_04252 BSBS38_04252 3987656 3988555 - uncharacterized protein gene gene4251 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04252 BSBS38_04253 BSBS38_04253 BSBS38_04253 3988782 3990137 + Putative metabolite transport protein YyaJ Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene4252 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04253 BSBS38_04254 BSBS38_04254 BSBS38_04254 3990171 3990725 - Maltose O-acetyltransferase Belongs to the transferase hexapeptide repeat family%3B KEGG: daf:Desaf_1005 maltose O-acetyltransferase gene gene4253 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04254 BSBS38_04255 BSBS38_04255 BSBS38_04255 3990743 3991123 - Lactoylglutathione lyase KEGG: msu:MS0597 lactoylglutathione lyase gene gene4254 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04255 BSBS38_04256 BSBS38_04256 BSBS38_04256 3991179 3992114 - Catabolite control protein Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene4255 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04256 BSBS38_04257 BSBS38_04257 xthA xthA 3992173 3992931 - Exodeoxyribonuclease III Belongs to the DNA repair enzymes AP/ExoA family%3B KEGG: bsu:BSU40880 exodeoxyribonuclease III gene gene4256 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04257 BSBS38_04258 BSBS38_04258 BSBS38_04258 3992993 3993232 - 30S ribosomal protein S18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%2C where it helps stabilize the platform of the 30S subunit%3B Belongs to the ribosomal protein S18P family gene gene4257 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04258 BSBS38_04259 BSBS38_04259 BSBS38_04259 3993276 3993794 - Single-stranded DNA-binding protein Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene4258 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04259 BSBS38_04260 BSBS38_04260 BSBS38_04260 3993835 3994122 - 30S ribosomal protein S6%2C chloroplastic Binds together with S18 to 16S ribosomal RNA%3B Belongs to the ribosomal protein S6P family gene gene4259 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04260 BSBS38_04261 BSBS38_04261 BSBS38_04261 3994233 3995333 - Ribosome-binding ATPase YchF ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene4260 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04261 BSBS38_04262 BSBS38_04262 BSBS38_04262 3995460 3997463 - Formate dehydrogenase Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: mmc:Mmcs_2009 formate dehydrogenase gene gene4261 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04262 BSBS38_04263 BSBS38_04263 BSBS38_04263 3997514 3997720 - uncharacterized protein gene gene4262 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04263 BSBS38_04264 BSBS38_04264 BSBS38_04264 3997814 3998812 - uncharacterized protein gene gene4263 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04264 BSBS38_04265 BSBS38_04265 BSBS38_04265 3999290 3999907 + uncharacterized protein gene gene4264 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04265 BSBS38_04266 BSBS38_04266 BSBS38_04266 3999946 4000794 - Stage 0 sporulation protein J Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division%2C and antagonizes Soj in response to cell cycle events related to chromosome partitioning%3B Belongs to the ParB family gene gene4265 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04266 BSBS38_04267 BSBS38_04267 BSBS38_04267 4000787 4001548 - Putative septum site-determining protein MinD ATPase required for the correct placement of the division site%3B Belongs to the ParA family. MinD subfamily gene gene4266 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04267 BSBS38_04268 BSBS38_04268 BSBS38_04268 4001796 4002236 + uncharacterized protein gene gene4267 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04268 BSBS38_04269 BSBS38_04269 BSBS38_04269 4002287 4003138 - Nucleoid occlusion protein Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid%2C especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid%2C which would cause chromosome breakage%3B Belongs to the ParB family gene gene4268 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04269 BSBS38_04270 BSBS38_04270 gidB gidB 4003260 4003979 - 16S rRNA (guanine(527)-N(7))-methyltransferase Specifically methylates the N7 position of guanine in position 535 of 16S rRNA%3B Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family%3B KEGG: bsu:BSU41000 16S rRNA (guanine527-N7)-methyltransferase gene gene4269 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04270 BSBS38_04271 BSBS38_04271 BSBS38_04271 4003993 4005879 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA-cmnm(5)s(2)U34%3B Belongs to the MnmG family gene gene4270 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04271 BSBS38_04272 BSBS38_04272 mnmE mnmE 4005900 4007279 - tRNA modification GTPase MnmE Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA- cmnm(5)s(2)U34%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family%3B Contains 1 TrmE-type G (guanine nucleotide-binding) domain%3B KEGG: bsu:BSU41020 tRNA modification GTPase%3B Acting on acid anhydrides gene gene4271 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04272 BSBS38_04273 BSBS38_04273 BSBS38_04273 4007590 4008216 - Protein jag Contains 1 KH domain%3B Contains 1 R3H domain gene gene4272 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04273 BSBS38_04274 BSBS38_04274 BSBS38_04274 4008213 4008992 - Membrane protein insertase MisCA Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. Essential for sporulation by activating sigma factor SpoIIIG/SigG after engulfment is completed in the prespore%2C maybe by acting on SpoIIIAE. It has an overlapping%2C although partly distinct%2C function compared to YqjG(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene4273 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04274 BSBS38_04275 BSBS38_04275 rnpA rnpA 4009142 4009492 - Ribonuclease P RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4. 5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme%3B Belongs to the RnpA family%3B KEGG: bsu:BSU41050 ribonuclease P protein component gene gene4274 http://www.ncbi.nlm.nih.gov/gene/?term=BSBS38_04275