locus-tag	class	description
BCV50_00115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCV50_00115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCV50_00135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BCV50_00155	COG1780	Probably involved in ribonucleotide reductase function
BCV50_00165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV50_00175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV50_00195	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BCV50_00200	COG1388	LysM domain
BCV50_00200	COG3584	3D domain protein
BCV50_00260	COG5434	Belongs to the glycosyl hydrolase 28 family
BCV50_00265	COG4195	phage-related replication protein
BCV50_00275	COG1216	Glycosyl transferase, family 2
BCV50_00345	COG0740	serine-type endopeptidase activity
BCV50_00390	COG5280	Phage tail tape measure protein TP901
BCV50_00390	COG3953	SLT domain
BCV50_00425	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCV50_00425	COG3409	Peptidoglycan-binding domain 1 protein
BCV50_00425	COG1388	LysM domain
BCV50_00475	COG1902	pentaerythritol trinitrate reductase activity
BCV50_00490	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV50_00495	COG0584	glycerophosphoryl diester phosphodiesterase
BCV50_00500	COG0183	Belongs to the thiolase family
BCV50_00505	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCV50_00510	COG1960	acyl-CoA dehydrogenase activity
BCV50_00515	COG0372	Belongs to the citrate synthase family
BCV50_00520	COG2079	MmgE PrpD family protein
BCV50_00525	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BCV50_00535	COG3829	transcription factor binding
BCV50_00535	COG3290	protein histidine kinase activity
BCV50_00540	COG0280	phosphate acetyltransferase
BCV50_00545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCV50_00550	COG3426	butyrate kinase activity
BCV50_00555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV50_00560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCV50_00565	COG0022	dehydrogenase e1 component
BCV50_00570	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV50_00575	COG4978	Transcriptional regulator
BCV50_00575	COG0789	Transcriptional regulator
BCV50_00580	COG2814	Major facilitator Superfamily
BCV50_00585	COG1597	lipid kinase activity
BCV50_00595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV50_00600	COG0765	amino acid transport
BCV50_00605	COG1126	abc transporter atp-binding protein
BCV50_00610	COG4129	membrane
BCV50_00615	COG1376	ErfK ybiS ycfS ynhG family protein
BCV50_00625	COG0346	lactoylglutathione lyase activity
BCV50_00630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCV50_00635	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCV50_00640	COG3361	conserved protein (COG2071)
BCV50_00645	COG0706	membrane insertase activity
BCV50_00655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCV50_00660	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BCV50_00665	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCV50_00670	COG1234	tRNA 3'-trailer cleavage
BCV50_00680	COG0596	Alpha beta hydrolase
BCV50_00685	COG1902	pentaerythritol trinitrate reductase activity
BCV50_00690	COG4187	Peptidase family M20/M25/M40
BCV50_00695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCV50_00700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV50_00705	COG0300	oxidoreductase activity
BCV50_00710	COG3048	D-serine ammonia-lyase activity
BCV50_00715	COG1072	(Pantothenic acid kinase))
BCV50_00720	COG0346	lactoylglutathione lyase activity
BCV50_00730	COG2211	Major facilitator Superfamily
BCV50_00745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCV50_00755	COG0456	acetyltransferase
BCV50_00760	COG2329	Antibiotic biosynthesis monooxygenase
BCV50_00765	COG0456	acetyltransferase
BCV50_00765	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCV50_00770	COG4918	Iron-sulphur cluster biosynthesis
BCV50_00780	COG1073	alpha beta
BCV50_00790	COG0667	Aldo Keto reductase
BCV50_00800	COG0494	nUDIX hydrolase
BCV50_00805	COG1379	DNA repair
BCV50_00810	COG1396	sequence-specific DNA binding
BCV50_00815	COG0252	asparaginase activity
BCV50_00820	COG1027	Aspartate ammonia-lyase
BCV50_00825	COG1757	Na H antiporter
BCV50_00830	COG0281	malic enzyme
BCV50_00840	COG1300	Membrane
BCV50_00845	COG0735	belongs to the Fur family
BCV50_00855	COG4974	Belongs to the 'phage' integrase family
BCV50_00860	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BCV50_00865	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BCV50_00870	COG1686	Belongs to the peptidase S11 family
BCV50_00875	COG1366	Belongs to the anti-sigma-factor antagonist family
BCV50_00880	COG2172	sigma factor antagonist activity
BCV50_00885	COG1191	sigma factor activity
BCV50_00905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCV50_00920	COG0697	spore germination
BCV50_00925	COG0019	diaminopimelate decarboxylase activity
BCV50_00930	COG4086	secreted protein
BCV50_00940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCV50_00950	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BCV50_00955	COG0681	Belongs to the peptidase S26 family
BCV50_00965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV50_00965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV50_00970	COG0307	riboflavin synthase, alpha
BCV50_00975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCV50_00975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCV50_00980	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BCV50_00985	COG0456	acetyltransferase
BCV50_00990	COG1547	Domain of unknown function (DUF309)
BCV50_00995	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BCV50_01000	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BCV50_01010	COG1686	Belongs to the peptidase S11 family
BCV50_01015	COG2715	membrane protein required for spore maturation
BCV50_01020	COG0700	Nucleoside recognition
BCV50_01025	COG1187	pseudouridine synthase activity
BCV50_01030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV50_01035	COG1333	cytochrome c biogenesis protein
BCV50_01040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCV50_01045	COG0745	RESPONSE REGULATOR receiver
BCV50_01050	COG5002	protein histidine kinase activity
BCV50_01055	COG1595	DNA-templated transcription, initiation
BCV50_01065	COG0710	3-dehydroquinate dehydratase activity
BCV50_01070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCV50_01075	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BCV50_01080	COG1141	Ferredoxin
BCV50_01085	COG4955	Helix-turn-helix domain
BCV50_01090	COG0514	ATP-dependent DNA helicase (RecQ)
BCV50_01095	COG1266	CAAX protease self-immunity
BCV50_01100	COG1388	LysM domain
BCV50_01110	COG1408	metallophosphoesterase
BCV50_01115	COG4862	establishment of competence for transformation
BCV50_01120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCV50_01125	COG0492	ferredoxin-NADP+ reductase activity
BCV50_01130	COG2339	peptidase activity
BCV50_01135	COG3409	Peptidoglycan-binding domain 1 protein
BCV50_01135	COG3773	Cell wall hydrolase
BCV50_01140	COG2959	enzyme of heme biosynthesis
BCV50_01145	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BCV50_01155	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCV50_01160	COG0539	negative regulation of cytoplasmic translation
BCV50_01165	COG1304	FMN binding
BCV50_01190	COG1160	GTP binding
BCV50_01195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BCV50_01210	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCV50_01215	COG0776	regulation of translation
BCV50_01220	COG0302	gtp cyclohydrolase
BCV50_01230	COG0142	geranyltranstransferase activity
BCV50_01235	COG2226	methyltransferase
BCV50_01240	COG0142	geranyltranstransferase activity
BCV50_01245	COG0105	UTP biosynthetic process
BCV50_01250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCV50_01255	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCV50_01260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BCV50_01265	COG4401	Chorismate mutase type I
BCV50_01270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCV50_01275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCV50_01285	COG0135	phosphoribosylanthranilate isomerase activity
BCV50_01290	COG0133	tryptophan synthase activity
BCV50_01295	COG0159	tryptophan synthase activity
BCV50_01300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCV50_01305	COG0287	Prephenate dehydrogenase
BCV50_01310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BCV50_01315	COG0457	Tetratricopeptide repeat
BCV50_01320	COG5582	Belongs to the UPF0302 family
BCV50_01330	COG0723	plastoquinol--plastocyanin reductase activity
BCV50_01335	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCV50_01340	COG2010	Cytochrome c
BCV50_01340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCV50_01345	COG4347	Protein of unknown function (DUF1405)
BCV50_01355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCV50_01360	COG1694	Mazg nucleotide pyrophosphohydrolase
BCV50_01365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCV50_01370	COG1803	Methylglyoxal synthase
BCV50_01375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCV50_01380	COG0438	transferase activity, transferring glycosyl groups
BCV50_01385	COG0617	tRNA 3'-terminal CCA addition
BCV50_01390	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BCV50_01390	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BCV50_01395	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BCV50_01400	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCV50_01405	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BCV50_01410	COG1199	ATP-dependent helicase activity
BCV50_01410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV50_01420	COG5353	protein conserved in bacteria
BCV50_01425	COG0436	Aminotransferase
BCV50_01430	COG0017	Asparaginyl-tRNA synthetase
BCV50_01435	COG3935	DnaD domain protein
BCV50_01440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCV50_01450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV50_01450	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCV50_01455	COG3331	DNA recombination
BCV50_01490	COG0071	Belongs to the small heat shock protein (HSP20) family
BCV50_01495	COG2190	(PTS) system
BCV50_01500	COG1205	dead DEAH box helicase
BCV50_01500	COG1111	helicase
BCV50_01505	COG3359	exonuclease
BCV50_01515	COG4474	Belongs to the UPF0398 family
BCV50_01530	COG0116	Belongs to the methyltransferase superfamily
BCV50_01540	COG1199	ATP-dependent helicase activity
BCV50_01545	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_01550	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BCV50_01555	COG1609	Transcriptional regulator
BCV50_01560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV50_01565	COG0800	Aldolase
BCV50_01575	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BCV50_01580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCV50_01585	COG2233	PERMEase
BCV50_01590	COG3424	synthase
BCV50_01595	COG1755	Isoprenylcysteine carboxyl methyltransferase
BCV50_01600	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCV50_01615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCV50_01625	COG0328	RNA-DNA hybrid ribonuclease activity
BCV50_01630	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BCV50_01635	COG0328	RNA-DNA hybrid ribonuclease activity
BCV50_01655	COG1278	Cold shock
BCV50_01660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCV50_01665	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BCV50_01670	COG0386	Belongs to the glutathione peroxidase family
BCV50_01675	COG1418	mRNA catabolic process
BCV50_01680	COG1413	lyase activity
BCV50_01685	COG0129	dihydroxy-acid dehydratase activity
BCV50_01695	COG2136	Putative SAM-dependent methyltransferase
BCV50_01695	COG2521	methyltransferase
BCV50_01705	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCV50_01715	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BCV50_01720	COG0204	Acyl-transferase
BCV50_01725	COG1272	protein, Hemolysin III
BCV50_01730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCV50_01735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCV50_01750	COG1999	signal sequence binding
BCV50_01755	COG2755	lipolytic protein G-D-S-L family
BCV50_01760	COG4698	Protein conserved in bacteria
BCV50_01770	COG0534	Mate efflux family protein
BCV50_01775	COG1846	Transcriptional regulator
BCV50_01780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCV50_01795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCV50_01800	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BCV50_01805	COG4641	Protein conserved in bacteria
BCV50_01820	COG0463	Glycosyl transferase, family 2
BCV50_01825	COG0456	acetyltransferase
BCV50_01835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCV50_01840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BCV50_01845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BCV50_01850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV50_01855	COG0456	acetyltransferase
BCV50_01860	COG1509	lysine 2,3-aminomutase activity
BCV50_01870	COG4479	Belongs to the UPF0346 family
BCV50_01895	COG0671	phosphoesterase, PA-phosphatase related
BCV50_01910	COG0813	purine-nucleoside phosphorylase activity
BCV50_01915	COG1876	peptidase activity
BCV50_01925	COG2226	methyltransferase
BCV50_01930	COG0793	Belongs to the peptidase S41A family
BCV50_01930	COG3409	Peptidoglycan-binding domain 1 protein
BCV50_01935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCV50_01945	COG0346	lactoylglutathione lyase activity
BCV50_01950	COG0400	carboxylic ester hydrolase activity
BCV50_01955	COG0778	Nitroreductase
BCV50_01960	COG1733	regulation of RNA biosynthetic process
BCV50_01970	COG1942	4-Oxalocrotonate Tautomerase
BCV50_01975	COG2610	gluconate transmembrane transporter activity
BCV50_01990	COG2962	Rard protein
BCV50_02000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCV50_02005	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCV50_02010	COG1366	Belongs to the anti-sigma-factor antagonist family
BCV50_02015	COG0534	Mate efflux family protein
BCV50_02020	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BCV50_02025	COG1819	glycosyl
BCV50_02030	COG0791	NLP P60 protein
BCV50_02030	COG1388	LysM domain
BCV50_02035	COG2032	superoxide dismutase activity
BCV50_02040	COG0714	Associated with various cellular activities
BCV50_02045	COG4548	von Willebrand factor, type A
BCV50_02050	COG0567	Dehydrogenase, E1 component
BCV50_02055	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV50_02060	COG0385	Bile acid
BCV50_02065	COG0733	neurotransmitter:sodium symporter activity
BCV50_02070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCV50_02075	COG1657	PFAM Prenyltransferase squalene oxidase
BCV50_02080	COG1012	belongs to the aldehyde dehydrogenase family
BCV50_02095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCV50_02100	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BCV50_02110	COG0514	ATP-dependent DNA helicase (RecQ)
BCV50_02115	COG1388	LysM domain
BCV50_02115	COG3584	3D domain protein
BCV50_02120	COG2197	response regulator
BCV50_02125	COG4585	Histidine kinase
BCV50_02130	COG3239	Fatty acid desaturase
BCV50_02135	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCV50_02150	COG2322	membrane
BCV50_02155	COG0741	lytic transglycosylase activity
BCV50_02160	COG0640	Transcriptional regulator
BCV50_02170	COG2378	regulation of single-species biofilm formation
BCV50_02175	COG3708	Transcriptional regulator
BCV50_02180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV50_02185	COG1309	transcriptional regulator
BCV50_02190	COG0456	acetyltransferase
BCV50_02195	COG0662	Cupin 2, conserved barrel domain protein
BCV50_02195	COG2207	Transcriptional regulator
BCV50_02200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV50_02230	COG1525	nuclease
BCV50_02240	COG4282	regulation of fungal-type cell wall biogenesis
BCV50_02245	COG5444	nuclease activity
BCV50_02270	COG1404	Belongs to the peptidase S8 family
BCV50_02270	COG4935	Belongs to the peptidase S8 family
BCV50_02300	COG0457	Tetratricopeptide repeat
BCV50_02315	COG1404	Belongs to the peptidase S8 family
BCV50_02315	COG4935	Belongs to the peptidase S8 family
BCV50_02335	COG3655	Transcriptional regulator
BCV50_02435	COG0582	viral genome integration into host DNA
BCV50_02450	COG0726	polysaccharide deacetylase
BCV50_02455	COG1231	oxidoreductase activity
BCV50_02460	COG4282	regulation of fungal-type cell wall biogenesis
BCV50_02465	COG5444	nuclease activity
BCV50_02480	COG0574	Belongs to the PEP-utilizing enzyme family
BCV50_02480	COG3848	Pyruvate phosphate dikinase
BCV50_02485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV50_02490	COG3397	chitin binding
BCV50_02495	COG4282	regulation of fungal-type cell wall biogenesis
BCV50_02500	COG2367	Beta-lactamase
BCV50_02505	COG0693	protein deglycase activity
BCV50_02515	COG1388	LysM domain
BCV50_02525	COG0697	spore germination
BCV50_02530	COG0583	DNA-binding transcription factor activity
BCV50_02535	COG3739	integral membrane protein
BCV50_02540	COG3655	Transcriptional regulator
BCV50_02550	COG2720	vancomycin resistance protein
BCV50_02575	COG0457	Tetratricopeptide repeat
BCV50_02590	COG2135	peptidase activity
BCV50_02605	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_02615	COG3619	membrane
BCV50_02620	COG4305	rare lipoprotein A
BCV50_02625	COG2368	4-hydroxyphenylacetate
BCV50_02630	COG5278	phosphoserine phosphatase activity
BCV50_02630	COG0840	transmembrane signaling receptor activity
BCV50_02645	COG1082	Xylose isomerase domain protein TIM barrel
BCV50_02660	COG0243	molybdopterin cofactor binding
BCV50_02665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCV50_02670	COG1070	Carbohydrate kinase
BCV50_02675	COG2814	Major facilitator Superfamily
BCV50_02685	COG1131	(ABC) transporter
BCV50_02700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV50_02710	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BCV50_02715	COG0300	oxidoreductase activity
BCV50_02730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BCV50_02735	COG0583	DNA-binding transcription factor activity
BCV50_02740	COG0070	glutamate synthase
BCV50_02740	COG0069	glutamate synthase activity
BCV50_02740	COG0067	glutamate synthase
BCV50_02745	COG0493	'glutamate synthase
BCV50_02750	COG0604	alcohol dehydrogenase
BCV50_02755	COG0583	DNA-binding transcription factor activity
BCV50_02760	COG0405	Gamma-glutamyltransferase
BCV50_02765	COG0166	Belongs to the GPI family
BCV50_02770	COG0582	viral genome integration into host DNA
BCV50_02785	COG0534	Mate efflux family protein
BCV50_02790	COG2017	converts alpha-aldose to the beta-anomer
BCV50_02795	COG2027	D-alanyl-D-alanine carboxypeptidase
BCV50_02800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_02805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_02810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_02815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_02820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_02820	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BCV50_02830	COG1649	PFAM Uncharacterised BCR, COG1649
BCV50_02840	COG1309	transcriptional regulator
BCV50_02850	COG1960	acyl-CoA dehydrogenase activity
BCV50_02855	COG0318	PFAM AMP-dependent synthetase and ligase
BCV50_02860	COG0439	Biotin carboxylase
BCV50_02865	COG0511	ligase activity, forming carbon-carbon bonds
BCV50_02870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCV50_02875	COG1024	Enoyl-CoA hydratase
BCV50_02880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCV50_02885	COG2404	hydrolase activity, acting on ester bonds
BCV50_02890	COG0586	Pfam SNARE associated Golgi protein
BCV50_02895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCV50_02900	COG2246	polysaccharide biosynthetic process
BCV50_02930	COG3507	Belongs to the glycosyl hydrolase 43 family
BCV50_02935	COG5520	Belongs to the glycosyl hydrolase 30 family
BCV50_02950	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCV50_02955	COG1115	amino acid carrier protein
BCV50_02970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCV50_02975	COG0187	DNA topoisomerase II activity
BCV50_02980	COG1832	CoA-binding protein
BCV50_02985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BCV50_02990	COG4841	protein insertion into membrane
BCV50_03000	COG0824	Thioesterase
BCV50_03020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV50_03025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCV50_03040	COG0071	Belongs to the small heat shock protein (HSP20) family
BCV50_03050	COG4846	Membrane protein involved in cytochrome C biogenesis
BCV50_03055	COG2201	protein-glutamate methylesterase activity
BCV50_03060	COG0785	Cytochrome C biogenesis protein
BCV50_03070	COG3763	UPF0154 protein
BCV50_03080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCV50_03085	COG4224	UPF0291 protein
BCV50_03090	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCV50_03095	COG1388	LysM domain
BCV50_03100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCV50_03110	COG0346	lactoylglutathione lyase activity
BCV50_03120	COG4195	phage-related replication protein
BCV50_03150	COG0531	amino acid
BCV50_03155	COG0697	spore germination
BCV50_03160	COG2059	Chromate
BCV50_03175	COG3832	glyoxalase III activity
BCV50_03185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCV50_03235	COG0756	dUTP diphosphatase activity
BCV50_03245	COG2814	Major facilitator Superfamily
BCV50_03260	COG1070	Carbohydrate kinase
BCV50_03275	COG3507	Belongs to the glycosyl hydrolase 43 family
BCV50_03280	COG2211	Major facilitator Superfamily
BCV50_03295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCV50_03305	COG0135	phosphoribosylanthranilate isomerase activity
BCV50_03385	COG0174	glutamine synthetase
BCV50_03390	COG0789	Transcriptional regulator
BCV50_03395	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BCV50_03400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCV50_03410	COG0464	growth
BCV50_03415	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV50_03420	COG4112	unkown
BCV50_03425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV50_03430	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV50_03435	COG1780	Probably involved in ribonucleotide reductase function
BCV50_03450	COG1923	regulation of RNA biosynthetic process
BCV50_03455	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCV50_03480	COG1764	response to oxidative stress
BCV50_03485	COG4195	phage-related replication protein
BCV50_03495	COG1404	Belongs to the peptidase S8 family
BCV50_03500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV50_03510	COG2124	cytochrome p450
BCV50_03515	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BCV50_03515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCV50_03515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCV50_03515	COG3321	synthase
BCV50_03520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_03520	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_03520	COG3321	synthase
BCV50_03520	COG4221	oxidoreductase activity
BCV50_03525	COG3321	synthase
BCV50_03525	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_03525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_03525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV50_03525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCV50_03530	COG4221	oxidoreductase activity
BCV50_03530	COG3321	synthase
BCV50_03530	COG0300	oxidoreductase activity
BCV50_03530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCV50_03535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_03535	COG0300	oxidoreductase activity
BCV50_03535	COG0318	PFAM AMP-dependent synthetase and ligase
BCV50_03535	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_03535	COG3321	synthase
BCV50_03540	COG1024	Enoyl-CoA hydratase
BCV50_03545	COG1024	Enoyl-CoA hydratase
BCV50_03550	COG3425	synthase
BCV50_03555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCV50_03560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCV50_03565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCV50_03565	COG2070	2-Nitropropane dioxygenase
BCV50_03570	COG3321	synthase
BCV50_03575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCV50_03585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV50_03590	COG3226	Transcriptional regulator
BCV50_03625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCV50_03630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCV50_03640	COG4550	Control of competence regulator ComK, YlbF/YmcA
BCV50_03645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCV50_03650	COG0156	8-amino-7-oxononanoate synthase activity
BCV50_03655	COG1063	alcohol dehydrogenase
BCV50_03660	COG2359	stage V sporulation protein S
BCV50_03665	COG1692	metallophosphoesterase
BCV50_03670	COG1418	mRNA catabolic process
BCV50_03675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV50_03680	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BCV50_03685	COG1058	Belongs to the CinA family
BCV50_03685	COG1546	Belongs to the CinA family
BCV50_03690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCV50_03695	COG1426	Protein conserved in bacteria
BCV50_03710	COG0300	oxidoreductase activity
BCV50_03715	COG0612	Peptidase, M16
BCV50_03720	COG0612	Peptidase, M16
BCV50_03725	COG2814	Major facilitator Superfamily
BCV50_03730	COG2188	Transcriptional regulator
BCV50_03735	COG4980	gas vesicle protein
BCV50_03735	COG1674	ftsk spoiiie
BCV50_03745	COG0740	serine-type endopeptidase activity
BCV50_03750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCV50_03755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCV50_03760	COG0527	aspartate kinase activity
BCV50_03765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCV50_03770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCV50_03775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCV50_03785	COG1873	PFAM PRC-barrel domain
BCV50_03790	COG0612	Peptidase, M16
BCV50_03795	COG0726	polysaccharide deacetylase
BCV50_03800	COG1185	polyribonucleotide nucleotidyltransferase activity
BCV50_03810	COG0196	riboflavin kinase activity
BCV50_03815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BCV50_03820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BCV50_03825	COG1550	Protein conserved in bacteria
BCV50_03830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BCV50_03835	COG1358	cellular component organization or biogenesis
BCV50_03840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BCV50_03845	COG0195	Participates in both transcription termination and antitermination
BCV50_03850	COG0779	Required for maturation of 30S ribosomal subunits
BCV50_03855	COG2176	DNA-directed DNA polymerase activity
BCV50_03860	COG0442	prolyl-tRNA aminoacylation
BCV50_03865	COG0750	zinc metalloprotease
BCV50_03870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BCV50_03875	COG4589	Belongs to the CDS family
BCV50_03880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCV50_03885	COG0233	cytoplasmic translational termination
BCV50_03890	COG0528	UMP kinase activity
BCV50_03895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BCV50_03900	COG0052	Belongs to the universal ribosomal protein uS2 family
BCV50_03910	COG1191	sigma factor activity
BCV50_03915	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BCV50_03920	COG1776	CheC inhibitor of MCP methylation
BCV50_03925	COG0835	chemotaxis
BCV50_03930	COG2198	Histidine kinase
BCV50_03930	COG0643	Histidine kinase
BCV50_03935	COG2201	protein-glutamate methylesterase activity
BCV50_03940	COG0455	bacterial-type flagellum organization
BCV50_03945	COG1419	protein localization to endoplasmic reticulum
BCV50_03950	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCV50_03955	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCV50_03960	COG1684	flagellar biosynthetic protein fliR
BCV50_03965	COG1987	bacterial-type flagellum assembly
BCV50_03970	COG1338	Plays a role in the flagellum-specific transport system
BCV50_03975	COG3190	flagellar
BCV50_03980	COG2201	protein-glutamate methylesterase activity
BCV50_03985	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCV50_03985	COG1776	CheC inhibitor of MCP methylation
BCV50_03990	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCV50_03995	COG1580	Controls the rotational direction of flagella during chemotaxis
BCV50_04000	COG1582	Flagellar protein (FlbD)
BCV50_04005	COG4786	Flagellar basal body rod
BCV50_04010	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BCV50_04015	COG3144	bacterial-type flagellum assembly
BCV50_04020	COG3334	PFAM MgtE intracellular
BCV50_04025	COG2882	bacterial-type flagellum organization
BCV50_04030	COG1157	protein secretion by the type III secretion system
BCV50_04035	COG1317	bacterial-type flagellum organization
BCV50_04040	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCV50_04045	COG1766	The M ring may be actively involved in energy transduction
BCV50_04050	COG1677	Flagellar hook-basal body complex protein FliE
BCV50_04055	COG1558	bacterial-type flagellum-dependent cell motility
BCV50_04060	COG1815	bacterial-type flagellum-dependent cell motility
BCV50_04065	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BCV50_04070	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BCV50_04075	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BCV50_04080	COG4974	Belongs to the 'phage' integrase family
BCV50_04085	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BCV50_04090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCV50_04095	COG0758	DNA mediated transformation
BCV50_04100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCV50_04105	COG0045	succinate-CoA ligase (ADP-forming) activity
BCV50_04110	COG2257	FlhB HrpN YscU SpaS Family
BCV50_04120	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BCV50_04125	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BCV50_04130	COG0335	large ribosomal subunit rRNA binding
BCV50_04135	COG0336	Belongs to the RNA methyltransferase TrmD family
BCV50_04140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCV50_04150	COG1837	Belongs to the UPF0109 family
BCV50_04155	COG0228	four-way junction DNA binding
BCV50_04160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCV50_04165	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BCV50_04175	COG0552	protein localization to endoplasmic reticulum
BCV50_04180	COG1196	nuclear chromosome segregation
BCV50_04185	COG0571	ribonuclease III activity
BCV50_04190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCV50_04195	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_04200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCV50_04205	COG0416	fatty acid biosynthetic process
BCV50_04210	COG1349	DNA-binding transcription factor activity
BCV50_04210	COG2050	protein possibly involved in aromatic compounds catabolism
BCV50_04215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCV50_04220	COG1760	l-serine dehydratase
BCV50_04225	COG1760	l-serine dehydratase
BCV50_04230	COG1461	Dihydroxyacetone kinase
BCV50_04235	COG1302	Protein conserved in bacteria
BCV50_04240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BCV50_04250	COG1564	THIamine pyrophosphokinase
BCV50_04255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCV50_04260	COG1162	GTPase activity
BCV50_04265	COG0515	serine threonine protein kinase
BCV50_04265	COG2815	serine threonine protein kinase
BCV50_04270	COG0631	protein serine/threonine phosphatase activity
BCV50_04275	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCV50_04280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCV50_04280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCV50_04285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCV50_04290	COG0242	peptide deformylase activity
BCV50_04295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCV50_04300	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCV50_04305	COG1758	RNA polymerase activity
BCV50_04310	COG0194	GDP metabolic process
BCV50_04315	COG2052	Domain of unknown function (DUF370)
BCV50_04320	COG1561	YicC-like family, N-terminal region
BCV50_04325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BCV50_04335	COG1648	precorrin-2 dehydrogenase activity
BCV50_04340	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BCV50_04345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCV50_04350	COG0529	Catalyzes the synthesis of activated sulfate
BCV50_04355	COG2046	Belongs to the sulfate adenylyltransferase family
BCV50_04360	COG0306	phosphate transporter
BCV50_04365	COG0175	sulfate reduction
BCV50_04370	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCV50_04375	COG0284	orotidine-5'-phosphate decarboxylase activity
BCV50_04380	COG0167	dihydroorotate dehydrogenase activity
BCV50_04385	COG0543	2 iron, 2 sulfur cluster binding
BCV50_04390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCV50_04395	COG0505	Belongs to the CarA family
BCV50_04400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCV50_04405	COG0540	Belongs to the ATCase OTCase family
BCV50_04410	COG2233	PERMEase
BCV50_04415	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BCV50_04420	COG0564	pseudouridine synthase activity
BCV50_04425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BCV50_04430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCV50_04435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BCV50_04440	COG3599	regulation of cell shape
BCV50_04445	COG2302	S4 RNA-binding domain
BCV50_04450	COG0762	integral membrane protein
BCV50_04455	COG1799	cell septum assembly
BCV50_04460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCV50_04470	COG1873	PFAM PRC-barrel domain
BCV50_04475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV50_04480	COG1119	ATPase activity
BCV50_04485	COG1191	sigma factor activity
BCV50_04490	COG1191	sigma factor activity
BCV50_04500	COG1404	Belongs to the peptidase S8 family
BCV50_04500	COG4412	M6 family metalloprotease domain protein
BCV50_04505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCV50_04510	COG0849	cell division
BCV50_04515	COG3856	small basic protein
BCV50_04520	COG3879	Bacterial protein of unknown function (DUF881)
BCV50_04525	COG3879	Bacterial protein of unknown function (DUF881)
BCV50_04530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCV50_04535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BCV50_04540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCV50_04545	COG0772	Belongs to the SEDS family
BCV50_04550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCV50_04555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCV50_04565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCV50_04570	COG0768	penicillin binding
BCV50_04585	COG4839	cell division protein FtsL
BCV50_04590	COG0275	rRNA processing
BCV50_04595	COG2001	Belongs to the MraZ family
BCV50_04600	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BCV50_04605	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCV50_04610	COG0454	-acetyltransferase
BCV50_04620	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCV50_04625	COG1399	metal-binding, possibly nucleic acid-binding protein
BCV50_04635	COG1323	Belongs to the UPF0348 family
BCV50_04640	COG3480	Lon protease (S16) C-terminal proteolytic domain
BCV50_04645	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCV50_04650	COG3314	Sporulation integral membrane protein YlbJ
BCV50_04655	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCV50_04660	COG0742	ribosomal rna small subunit methyltransferase
BCV50_04665	COG4471	UPF0298 protein
BCV50_04670	COG3679	Belongs to the UPF0342 family
BCV50_04685	COG2340	Cysteine-rich secretory protein family
BCV50_04690	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BCV50_04700	COG3336	cytochrome c oxidase
BCV50_04705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCV50_04710	COG1845	cytochrome c oxidase, subunit III
BCV50_04715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCV50_04720	COG2010	Cytochrome c
BCV50_04720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCV50_04725	COG0109	protoheme IX farnesyltransferase activity
BCV50_04730	COG1612	heme a metabolic process
BCV50_04740	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BCV50_04745	COG0772	Belongs to the SEDS family
BCV50_04750	COG4838	Belongs to the UPF0358 family
BCV50_04755	COG2066	Belongs to the glutaminase family
BCV50_04760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BCV50_04765	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BCV50_04775	COG4896	Protein conserved in bacteria
BCV50_04810	COG1959	2 iron, 2 sulfur cluster binding
BCV50_04820	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BCV50_04830	COG0483	inositol monophosphate 1-phosphatase activity
BCV50_04840	COG4493	Belongs to the UPF0637 family
BCV50_04845	COG4476	Belongs to the UPF0223 family
BCV50_04850	COG1982	Orn Lys Arg decarboxylase major
BCV50_04855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV50_04860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV50_04865	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV50_04870	COG0022	dehydrogenase e1 component
BCV50_04875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCV50_04880	COG0497	DNA recombination
BCV50_04890	COG0242	peptide deformylase activity
BCV50_04895	COG0561	phosphatase activity
BCV50_04905	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCV50_04910	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BCV50_04915	COG0569	domain protein
BCV50_04920	COG2105	PFAM AIG2 family protein
BCV50_04920	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BCV50_04925	COG3852	Histidine kinase
BCV50_04930	COG2002	toxin-antitoxin pair type II binding
BCV50_04935	COG1077	Cell shape determining protein MreB Mrl
BCV50_04945	COG2309	aminopeptidase activity
BCV50_04950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCV50_04955	COG0488	(ABC) transporter
BCV50_04965	COG0681	Belongs to the peptidase S26 family
BCV50_04970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV50_04970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV50_04970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV50_04975	COG1105	Belongs to the carbohydrate kinase PfkB family
BCV50_04980	COG1349	DNA-binding transcription factor activity
BCV50_04985	COG0577	efflux transmembrane transporter activity
BCV50_04990	COG1136	(ABC) transporter
BCV50_04995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV50_05005	COG1132	(ABC) transporter
BCV50_05010	COG1132	(ABC) transporter
BCV50_05015	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BCV50_05020	COG0314	molybdopterin synthase activity
BCV50_05025	COG1763	Mo-molybdopterin cofactor biosynthetic process
BCV50_05030	COG0303	'Molybdopterin
BCV50_05035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCV50_05040	COG0746	molybdenum cofactor guanylyltransferase activity
BCV50_05055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV50_05060	COG0450	alkyl hydroperoxide reductase
BCV50_05065	COG0668	transmembrane transport
BCV50_05075	COG1473	amidohydrolase
BCV50_05080	COG2171	N-acyltransferase activity
BCV50_05085	COG0716	FMN binding
BCV50_05095	COG0716	FMN binding
BCV50_05100	COG0583	DNA-binding transcription factor activity
BCV50_05105	COG0517	IMP dehydrogenase activity
BCV50_05115	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BCV50_05120	COG4703	Protein of unknown function (DUF1797)
BCV50_05125	COG2200	EAL domain
BCV50_05130	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_05135	COG1408	metallophosphoesterase
BCV50_05140	COG1376	ErfK ybiS ycfS ynhG family protein
BCV50_05145	COG2814	Major facilitator Superfamily
BCV50_05155	COG0835	chemotaxis
BCV50_05155	COG0784	Response regulator, receiver
BCV50_05165	COG0436	Aminotransferase
BCV50_05170	COG4191	Histidine kinase
BCV50_05175	COG0768	penicillin binding
BCV50_05180	COG2340	Cysteine-rich secretory protein family
BCV50_05190	COG4257	antibiotic catabolic process
BCV50_05195	COG2084	Dehydrogenase
BCV50_05200	COG0840	transmembrane signaling receptor activity
BCV50_05205	COG0456	acetyltransferase
BCV50_05210	COG1533	DNA photolyase activity
BCV50_05220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCV50_05225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV50_05230	COG2190	(PTS) system
BCV50_05230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_05230	COG1263	PTS System
BCV50_05235	COG3711	transcriptional antiterminator
BCV50_05240	COG1609	Transcriptional regulator
BCV50_05250	COG0006	proline dipeptidase activity
BCV50_05260	COG2217	Heavy metal translocating P-type atpase
BCV50_05265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV50_05270	COG2244	polysaccharide biosynthetic process
BCV50_05275	COG3773	Cell wall hydrolase
BCV50_05290	COG4873	Protein conserved in bacteria
BCV50_05300	COG3858	chitin binding
BCV50_05305	COG1388	LysM domain
BCV50_05310	COG4641	Protein conserved in bacteria
BCV50_05310	COG1388	LysM domain
BCV50_05315	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCV50_05320	COG0602	queuosine metabolic process
BCV50_05325	COG0720	synthase
BCV50_05330	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BCV50_05335	COG3949	Membrane
BCV50_05340	COG0542	response to heat
BCV50_05345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCV50_05350	COG1360	Flagellar Motor Protein
BCV50_05355	COG1846	Transcriptional regulator
BCV50_05360	COG3852	Histidine kinase
BCV50_05375	COG3339	Conserved Protein
BCV50_05380	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BCV50_05385	COG0235	Class ii aldolase
BCV50_05390	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BCV50_05395	COG1850	ribulose-bisphosphate carboxylase activity
BCV50_05400	COG0436	Aminotransferase
BCV50_05405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV50_05410	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BCV50_05415	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BCV50_05425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCV50_05430	COG5002	protein histidine kinase activity
BCV50_05435	COG3594	Acyltransferase
BCV50_05450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCV50_05455	COG0501	Belongs to the peptidase M48B family
BCV50_05475	COG1191	sigma factor activity
BCV50_05480	COG0861	Integral membrane protein TerC family
BCV50_05485	COG0586	Pfam SNARE associated Golgi protein
BCV50_05490	COG3300	MHYT domain
BCV50_05490	COG5001	Diguanylate cyclase
BCV50_05495	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BCV50_05500	COG3285	dna ligase
BCV50_05500	COG1793	dna ligase
BCV50_05505	COG0463	Glycosyl transferase, family 2
BCV50_05515	COG1408	metallophosphoesterase
BCV50_05520	COG0726	polysaccharide deacetylase
BCV50_05525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCV50_05530	COG1846	Transcriptional regulator
BCV50_05545	COG0789	Transcriptional regulator
BCV50_05550	COG2239	Acts as a magnesium transporter
BCV50_05565	COG3212	peptidase
BCV50_05570	COG3212	peptidase
BCV50_05575	COG3850	Histidine kinase
BCV50_05575	COG5002	protein histidine kinase activity
BCV50_05580	COG0745	RESPONSE REGULATOR receiver
BCV50_05590	COG4721	ABC-type cobalt transport system, permease component
BCV50_05595	COG1122	ATPase activity
BCV50_05600	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BCV50_05605	COG1366	Belongs to the anti-sigma-factor antagonist family
BCV50_05610	COG1404	Belongs to the peptidase S8 family
BCV50_05615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCV50_05620	COG0406	alpha-ribazole phosphatase activity
BCV50_05625	COG0590	tRNA wobble adenosine to inosine editing
BCV50_05630	COG0457	Tetratricopeptide repeat
BCV50_05630	COG0463	Glycosyl transferase, family 2
BCV50_05635	COG1764	response to oxidative stress
BCV50_05640	COG1846	Transcriptional regulator
BCV50_05645	COG1764	response to oxidative stress
BCV50_05650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BCV50_05655	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BCV50_05660	COG0788	formyltetrahydrofolate deformylase activity
BCV50_05665	COG2076	Multidrug Resistance protein
BCV50_05670	COG2076	Multidrug Resistance protein
BCV50_05675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV50_05680	COG2318	DinB family
BCV50_05685	COG2323	membrane
BCV50_05695	COG1017	nitric oxide dioxygenase activity
BCV50_05695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV50_05700	COG1607	acyl-coa hydrolase
BCV50_05705	COG1834	amidinotransferase
BCV50_05710	COG2706	6-phosphogluconolactonase activity
BCV50_05715	COG4608	Belongs to the ABC transporter superfamily
BCV50_05720	COG0791	NLP P60 protein
BCV50_05725	COG4948	Mandelate Racemase Muconate Lactonizing
BCV50_05730	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCV50_05735	COG4166	transmembrane transport
BCV50_05740	COG0444	Belongs to the ABC transporter superfamily
BCV50_05745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV50_05750	COG0601	transmembrane transport
BCV50_05755	COG2362	D-Aminopeptidase
BCV50_05760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCV50_05765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV50_05775	COG0463	Glycosyl transferase, family 2
BCV50_05780	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BCV50_05785	COG0346	lactoylglutathione lyase activity
BCV50_05790	COG0531	amino acid
BCV50_05795	COG1392	Phosphate transport regulator
BCV50_05800	COG0306	phosphate transporter
BCV50_05815	COG3594	Acyltransferase
BCV50_05820	COG3409	Peptidoglycan-binding domain 1 protein
BCV50_05820	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCV50_05860	COG3778	Protein conserved in bacteria
BCV50_05865	COG3299	homolog of phage Mu protein gp47
BCV50_05870	COG3628	GPW Gp25 family protein
BCV50_05880	COG4193	domain, Protein
BCV50_05885	COG1652	LysM domain
BCV50_05890	COG5412	phage tail tape measure protein
BCV50_05890	COG3953	SLT domain
BCV50_05940	COG4653	Phage capsid family
BCV50_05945	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BCV50_05950	COG5518	Phage portal protein
BCV50_05955	COG1783	phage Terminase large subunit
BCV50_05960	COG5484	DNA packaging
BCV50_05960	COG3728	DNA packaging
BCV50_05965	COG1595	DNA-templated transcription, initiation
BCV50_05990	COG1484	DNA-dependent DNA replication
BCV50_05995	COG1522	sequence-specific DNA binding
BCV50_06005	COG1396	sequence-specific DNA binding
BCV50_06010	COG2856	Zn peptidase
BCV50_06015	COG3546	catalase activity
BCV50_06020	COG4195	phage-related replication protein
BCV50_06030	COG1388	LysM domain
BCV50_06030	COG3409	Peptidoglycan-binding domain 1 protein
BCV50_06030	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCV50_06035	COG2350	Protein conserved in bacteria
BCV50_06045	COG0457	Tetratricopeptide repeat
BCV50_06050	COG2318	DinB family
BCV50_06055	COG0730	response to heat
BCV50_06060	COG2721	sulfolactate sulfo-lyase activity
BCV50_06065	COG0246	Mannitol dehydrogenase
BCV50_06070	COG1609	Transcriptional regulator
BCV50_06075	COG2271	Major facilitator Superfamily
BCV50_06080	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_06085	COG1312	Catalyzes the dehydration of D-mannonate
BCV50_06090	COG1063	alcohol dehydrogenase
BCV50_06095	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BCV50_06100	COG2211	Major facilitator Superfamily
BCV50_06105	COG1904	glucuronate isomerase
BCV50_06110	COG1252	NADH dehydrogenase
BCV50_06120	COG4297	protein containing double-stranded beta helix domain
BCV50_06125	COG0697	spore germination
BCV50_06130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCV50_06135	COG0390	transport system, permease component
BCV50_06140	COG1587	Uroporphyrinogen-III synthase
BCV50_06150	COG1819	glycosyl
BCV50_06155	COG2124	cytochrome p450
BCV50_06165	COG1051	belongs to the nudix hydrolase family
BCV50_06175	COG2427	Protein of unknown function (DUF1641)
BCV50_06180	COG3383	formate dehydrogenase (NAD+) activity
BCV50_06190	COG2205	protein histidine kinase activity
BCV50_06195	COG5504	Zn-dependent protease
BCV50_06215	COG0726	polysaccharide deacetylase
BCV50_06225	COG0109	protoheme IX farnesyltransferase activity
BCV50_06235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCV50_06245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV50_06260	COG1482	cell wall glycoprotein biosynthetic process
BCV50_06265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV50_06265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV50_06265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV50_06270	COG3711	transcriptional antiterminator
BCV50_06270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV50_06280	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BCV50_06290	COG1388	LysM domain
BCV50_06290	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCV50_06290	COG3409	Peptidoglycan-binding domain 1 protein
BCV50_06330	COG0457	Tetratricopeptide repeat
BCV50_06355	COG5505	Protein of unknown function (DUF819)
BCV50_06360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV50_06365	COG0626	cystathionine gamma-synthase activity
BCV50_06370	COG0626	cystathionine gamma-synthase activity
BCV50_06375	COG2382	esterase
BCV50_06380	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BCV50_06385	COG2153	protein acetylation
BCV50_06410	COG0210	DNA helicase
BCV50_06470	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BCV50_06475	COG0351	phosphomethylpyrimidine kinase
BCV50_06480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCV50_06485	COG2022	thiamine diphosphate biosynthetic process
BCV50_06490	COG2104	thiamine diphosphate biosynthetic process
BCV50_06495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV50_06500	COG0352	thiamine-phosphate diphosphorylase activity
BCV50_06505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BCV50_06510	COG0475	glutathione-regulated potassium exporter activity
BCV50_06510	COG0569	domain protein
BCV50_06515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCV50_06520	COG0564	pseudouridine synthase activity
BCV50_06525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BCV50_06530	COG2357	RelA SpoT domain protein
BCV50_06540	COG4116	CYTH
BCV50_06545	COG0741	lytic transglycosylase activity
BCV50_06550	COG2346	COG2346, Truncated hemoglobins
BCV50_06570	COG1164	Oligoendopeptidase f
BCV50_06575	COG4469	Competence protein
BCV50_06580	COG4862	establishment of competence for transformation
BCV50_06585	COG0861	Integral membrane protein TerC family
BCV50_06590	COG1393	Belongs to the ArsC family
BCV50_06595	COG0456	acetyltransferase
BCV50_06600	COG2814	Major facilitator Superfamily
BCV50_06605	COG4608	Belongs to the ABC transporter superfamily
BCV50_06610	COG0444	Belongs to the ABC transporter superfamily
BCV50_06615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV50_06620	COG0601	transmembrane transport
BCV50_06625	COG4166	transmembrane transport
BCV50_06630	COG0180	Tryptophanyl-tRNA synthetase
BCV50_06640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV50_06645	COG0601	transmembrane transport
BCV50_06655	COG4608	Belongs to the ABC transporter superfamily
BCV50_06660	COG0444	Belongs to the ABC transporter superfamily
BCV50_06665	COG5504	Zn-dependent protease
BCV50_06670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCV50_06675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCV50_06690	COG1744	ABC transporter substrate-binding protein PnrA-like
BCV50_06700	COG2267	carboxylic ester hydrolase activity
BCV50_06715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BCV50_06720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCV50_06725	COG0505	Belongs to the CarA family
BCV50_06730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCV50_06745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BCV50_06750	COG2271	Major facilitator Superfamily
BCV50_06755	COG0277	FAD linked oxidase domain protein
BCV50_06765	COG2151	metal-sulfur cluster biosynthetic enzyme
BCV50_06770	COG1073	alpha beta
BCV50_06775	COG0561	phosphatase activity
BCV50_06795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCV50_06800	COG1307	EDD domain protein, DegV family
BCV50_06805	COG3227	Zinc metalloprotease (Elastase)
BCV50_06820	COG1695	Transcriptional regulator
BCV50_06840	COG2996	Protein conserved in bacteria
BCV50_06845	COG1666	GTP binding
BCV50_06850	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BCV50_06850	COG0646	methionine synthase
BCV50_06855	COG2153	protein acetylation
BCV50_06860	COG0454	-acetyltransferase
BCV50_06865	COG2814	Major facilitator Superfamily
BCV50_06870	COG4948	Mandelate Racemase Muconate Lactonizing
BCV50_06875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCV50_06880	COG1809	phosphosulfolactate synthase activity
BCV50_06885	COG2045	Belongs to the ComB family
BCV50_06890	COG0175	sulfate reduction
BCV50_06895	COG2046	Belongs to the sulfate adenylyltransferase family
BCV50_06900	COG0529	Catalyzes the synthesis of activated sulfate
BCV50_06905	COG2267	carboxylic ester hydrolase activity
BCV50_06910	COG1357	PFAM Pentapeptide repeats (8 copies)
BCV50_06915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV50_06920	COG1279	arginine transmembrane transporter activity
BCV50_06925	COG2318	DinB family
BCV50_06930	COG0673	inositol 2-dehydrogenase activity
BCV50_06935	COG1609	Transcriptional regulator
BCV50_06940	COG1917	Cupin 2, conserved barrel domain protein
BCV50_06940	COG2207	Transcriptional regulator
BCV50_06945	COG0534	Mate efflux family protein
BCV50_06950	COG1562	ergosterol biosynthetic process
BCV50_06955	COG0367	asparagine synthase
BCV50_06965	COG1404	Belongs to the peptidase S8 family
BCV50_06975	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCV50_06980	COG5337	Spore coat protein CotH
BCV50_07025	COG1403	HNH endonuclease
BCV50_07030	COG0419	ATPase involved in DNA repair
BCV50_07035	COG0420	3'-5' exonuclease activity
BCV50_07040	COG1074	ATP-dependent DNA helicase activity
BCV50_07045	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BCV50_07050	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BCV50_07060	COG4533	DNA binding
BCV50_07065	COG0477	Major facilitator Superfamily
BCV50_07065	COG2814	Major facilitator Superfamily
BCV50_07070	COG3180	Ammonia monooxygenase
BCV50_07075	COG1846	Transcriptional regulator
BCV50_07080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV50_07085	COG0681	Belongs to the peptidase S26 family
BCV50_07090	COG0398	Pfam SNARE associated Golgi protein
BCV50_07105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCV50_07115	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_07120	COG4903	ComK protein
BCV50_07130	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_07135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV50_07135	COG0723	plastoquinol--plastocyanin reductase activity
BCV50_07140	COG0840	transmembrane signaling receptor activity
BCV50_07145	COG1268	BioY protein
BCV50_07150	COG0318	PFAM AMP-dependent synthetase and ligase
BCV50_07155	COG0183	Belongs to the thiolase family
BCV50_07160	COG0406	alpha-ribazole phosphatase activity
BCV50_07165	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BCV50_07170	COG0604	alcohol dehydrogenase
BCV50_07175	COG0456	acetyltransferase
BCV50_07180	COG1404	Belongs to the peptidase S8 family
BCV50_07185	COG0501	Belongs to the peptidase M48B family
BCV50_07195	COG0318	PFAM AMP-dependent synthetase and ligase
BCV50_07200	COG0702	epimerase
BCV50_07205	COG0095	Lipoate-protein ligase
BCV50_07210	COG1234	tRNA 3'-trailer cleavage
BCV50_07220	COG1301	dicarboxylic acid transport
BCV50_07225	COG4405	Protein conserved in bacteria
BCV50_07230	COG1363	Peptidase, m42
BCV50_07240	COG4377	Putative membrane peptidase family (DUF2324)
BCV50_07245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCV50_07250	COG1511	domain protein
BCV50_07255	COG1309	transcriptional regulator
BCV50_07270	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BCV50_07275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV50_07280	COG2329	Antibiotic biosynthesis monooxygenase
BCV50_07290	COG3069	C4-dicarboxylate transmembrane transporter activity
BCV50_07295	COG1473	amidohydrolase
BCV50_07305	COG4473	ABC transporter
BCV50_07310	COG1131	(ABC) transporter
BCV50_07315	COG0537	adenosine 5'-monophosphoramidase activity
BCV50_07320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BCV50_07335	COG4980	gas vesicle protein
BCV50_07340	COG1846	Transcriptional regulator
BCV50_07360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV50_07370	COG3481	metal-dependent phosphohydrolase, HD sub domain
BCV50_07375	COG4717	serine-type aminopeptidase activity
BCV50_07380	COG0420	3'-5' exonuclease activity
BCV50_07385	COG1668	transmembrane transport
BCV50_07390	COG4152	abc transporter atp-binding protein
BCV50_07400	COG1024	Enoyl-CoA hydratase
BCV50_07410	COG0490	domain, Protein
BCV50_07415	COG0475	glutathione-regulated potassium exporter activity
BCV50_07420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCV50_07425	COG0561	phosphatase activity
BCV50_07430	COG4335	DNA alkylation repair
BCV50_07435	COG3679	Belongs to the UPF0342 family
BCV50_07440	COG4399	Belongs to the UPF0754 family
BCV50_07445	COG0189	ligase activity
BCV50_07450	COG0189	ligase activity
BCV50_07465	COG0702	epimerase
BCV50_07470	COG1132	(ABC) transporter
BCV50_07475	COG1132	(ABC) transporter
BCV50_07485	COG0589	response to stress
BCV50_07490	COG1757	Na H antiporter
BCV50_07495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCV50_07500	COG0726	polysaccharide deacetylase
BCV50_07505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BCV50_07510	COG0668	transmembrane transport
BCV50_07530	COG4932	domain protein
BCV50_07530	COG5492	domain, Protein
BCV50_07540	COG0584	glycerophosphoryl diester phosphodiesterase
BCV50_07545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCV50_07550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCV50_07555	COG1253	flavin adenine dinucleotide binding
BCV50_07560	COG0436	Aminotransferase
BCV50_07565	COG0789	Transcriptional regulator
BCV50_07570	COG1253	flavin adenine dinucleotide binding
BCV50_07580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV50_07585	COG0204	Acyl-transferase
BCV50_07590	COG0667	Aldo Keto reductase
BCV50_07595	COG1595	DNA-templated transcription, initiation
BCV50_07610	COG0456	acetyltransferase
BCV50_07615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV50_07620	COG0733	neurotransmitter:sodium symporter activity
BCV50_07625	COG0531	amino acid
BCV50_07630	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_07635	COG0372	Belongs to the citrate synthase family
BCV50_07640	COG0583	DNA-binding transcription factor activity
BCV50_07645	COG1388	LysM domain
BCV50_07645	COG0791	NLP P60 protein
BCV50_07650	COG1785	Belongs to the alkaline phosphatase family
BCV50_07655	COG2719	SpoVR family
BCV50_07660	COG0668	transmembrane transport
BCV50_07665	COG1959	2 iron, 2 sulfur cluster binding
BCV50_07670	COG0791	NLP P60 protein
BCV50_07670	COG1388	LysM domain
BCV50_07685	COG0431	NADPH-dependent FMN reductase
BCV50_07690	COG2197	response regulator
BCV50_07695	COG4585	Histidine kinase
BCV50_07695	COG2203	Gaf domain
BCV50_07700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV50_07705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCV50_07710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BCV50_07715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCV50_07720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BCV50_07725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCV50_07735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV50_07735	COG3153	acetyltransferase
BCV50_07740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV50_07745	COG0517	IMP dehydrogenase activity
BCV50_07755	COG0564	pseudouridine synthase activity
BCV50_07760	COG3764	Sortase (surface protein transpeptidase)
BCV50_07765	COG0737	Belongs to the 5'-nucleotidase family
BCV50_07765	COG1525	nuclease
BCV50_07765	COG4085	toxin activity
BCV50_07770	COG5577	PFAM Coat F domain
BCV50_07795	COG1396	sequence-specific DNA binding
BCV50_07800	COG0456	acetyltransferase
BCV50_07805	COG1823	symporter activity
BCV50_07810	COG3706	GGDEF domain
BCV50_07815	COG1464	Belongs to the NlpA lipoprotein family
BCV50_07820	COG1278	Cold shock
BCV50_07825	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCV50_07830	COG1131	(ABC) transporter
BCV50_07835	COG1131	(ABC) transporter
BCV50_07840	COG1725	Transcriptional regulator
BCV50_07855	COG0655	NAD(P)H dehydrogenase (quinone) activity
BCV50_07860	COG2814	Major facilitator Superfamily
BCV50_07865	COG1566	PFAM secretion protein HlyD family protein
BCV50_07870	COG1846	Transcriptional regulator
BCV50_07880	COG2718	Belongs to the UPF0229 family
BCV50_07885	COG2766	serine protein kinase
BCV50_07890	COG1664	Polymer-forming cytoskeletal
BCV50_07895	COG1664	Polymer-forming cytoskeletal
BCV50_07900	COG0789	Transcriptional regulator
BCV50_07905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCV50_07915	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCV50_07920	COG3382	B3 4 domain protein
BCV50_07930	COG1476	TRANSCRIPTIONal
BCV50_07940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BCV50_07950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV50_07955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCV50_07960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCV50_07965	COG1116	anion transmembrane transporter activity
BCV50_07970	COG0753	catalase activity
BCV50_07980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BCV50_07985	COG3340	Belongs to the peptidase S51 family
BCV50_07990	COG5577	PFAM Coat F domain
BCV50_08000	COG4326	sporulation control protein
BCV50_08115	COG0735	belongs to the Fur family
BCV50_08120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCV50_08125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCV50_08130	COG4129	membrane
BCV50_08135	COG1132	(ABC) transporter
BCV50_08140	COG3557	Belongs to the UPF0374 family
BCV50_08155	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_08165	COG1194	a g-specific adenine glycosylase
BCV50_08170	COG1988	membrane-bound metal-dependent
BCV50_08175	COG4485	Bacterial membrane protein, YfhO
BCV50_08180	COG0463	Glycosyl transferase, family 2
BCV50_08185	COG0596	Alpha beta hydrolase
BCV50_08190	COG5658	integral membrane protein
BCV50_08195	COG3103	Sh3 type 3 domain protein
BCV50_08210	COG2814	Major facilitator Superfamily
BCV50_08225	COG2137	regulation of response to DNA damage stimulus
BCV50_08230	COG1090	epimerase
BCV50_08245	COG0778	Nitroreductase
BCV50_08250	COG0384	phenazine biosynthesis protein PhzF
BCV50_08255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV50_08260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV50_08265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCV50_08270	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BCV50_08270	COG0392	lysyltransferase activity
BCV50_08275	COG1846	Transcriptional regulator
BCV50_08280	COG2814	Major facilitator Superfamily
BCV50_08285	COG2318	DinB family
BCV50_08290	COG2814	Major facilitator Superfamily
BCV50_08295	COG1309	transcriptional regulator
BCV50_08300	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BCV50_08305	COG1131	(ABC) transporter
BCV50_08325	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BCV50_08330	COG1695	Transcriptional regulator
BCV50_08340	COG0842	Transport permease protein
BCV50_08345	COG0842	Transport permease protein
BCV50_08345	COG1511	domain protein
BCV50_08350	COG1131	(ABC) transporter
BCV50_08355	COG2197	response regulator
BCV50_08360	COG4585	Histidine kinase
BCV50_08365	COG2514	catechol 2,3-dioxygenase activity
BCV50_08370	COG2259	Doxx family
BCV50_08375	COG1132	(ABC) transporter
BCV50_08380	COG1132	(ABC) transporter
BCV50_08385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_08385	COG1263	PTS System
BCV50_08390	COG1737	Transcriptional regulator
BCV50_08395	COG1486	melibiose metabolic process
BCV50_08400	COG4842	Belongs to the WXG100 family
BCV50_08420	COG1742	UPF0060 membrane protein
BCV50_08430	COG3284	Transcriptional regulator
BCV50_08435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV50_08440	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV50_08445	COG0022	dehydrogenase e1 component
BCV50_08450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCV50_08455	COG4637	Psort location Cytoplasmic, score
BCV50_08465	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BCV50_08475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCV50_08480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCV50_08485	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCV50_08490	COG0598	Magnesium transport protein CorA
BCV50_08495	COG2084	Dehydrogenase
BCV50_08500	COG0726	polysaccharide deacetylase
BCV50_08510	COG0535	radical SAM domain protein
BCV50_08515	COG0668	transmembrane transport
BCV50_08525	COG0387	Pfam Sodium calcium exchanger
BCV50_08535	COG0477	Major facilitator Superfamily
BCV50_08545	COG1295	ribonuclease BN
BCV50_08550	COG4980	gas vesicle protein
BCV50_08555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCV50_08560	COG4840	Belongs to the UPF0435 family
BCV50_08565	COG2814	Major facilitator Superfamily
BCV50_08570	COG0693	protein deglycase activity
BCV50_08575	COG0737	Belongs to the 5'-nucleotidase family
BCV50_08580	COG0778	Nitroreductase
BCV50_08585	COG2188	Transcriptional regulator
BCV50_08590	COG0366	Alpha amylase catalytic
BCV50_08595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_08595	COG1263	PTS System
BCV50_08610	COG1115	amino acid carrier protein
BCV50_08620	COG1368	sulfuric ester hydrolase activity
BCV50_08625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_08625	COG1263	PTS System
BCV50_08630	COG0024	Methionine aminopeptidase
BCV50_08650	COG2258	MOSC domain
BCV50_08655	COG1254	Belongs to the acylphosphatase family
BCV50_08660	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BCV50_08665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV50_08670	COG2851	Citrate transporter
BCV50_08680	COG3181	Tripartite tricarboxylate transporter family receptor
BCV50_08685	COG4565	transcriptional regulatory protein
BCV50_08690	COG3290	protein histidine kinase activity
BCV50_08695	COG0471	metal ion transport
BCV50_08700	COG3866	Pectate lyase
BCV50_08715	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BCV50_08720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV50_08725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV50_08730	COG1120	ATPase activity
BCV50_08735	COG2130	NADP-dependent
BCV50_08740	COG0456	acetyltransferase
BCV50_08745	COG0513	Belongs to the DEAD box helicase family
BCV50_08750	COG0488	(ABC) transporter
BCV50_08755	COG2814	Major facilitator Superfamily
BCV50_08760	COG0789	Transcriptional regulator
BCV50_08770	COG0488	(ABC) transporter
BCV50_08775	COG0840	transmembrane signaling receptor activity
BCV50_08780	COG1012	belongs to the aldehyde dehydrogenase family
BCV50_08785	COG0531	amino acid
BCV50_08790	COG1011	Hydrolase
BCV50_08795	COG2223	nitrite transmembrane transporter activity
BCV50_08800	COG1442	glycosyl transferase family 8
BCV50_08805	COG1216	Glycosyl transferase, family 2
BCV50_08810	COG1442	glycosyl transferase family 8
BCV50_08815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV50_08820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BCV50_08825	COG1368	sulfuric ester hydrolase activity
BCV50_08830	COG2124	cytochrome p450
BCV50_08830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCV50_08840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV50_08845	COG1846	Transcriptional regulator
BCV50_08850	COG0697	spore germination
BCV50_08855	COG0670	Belongs to the BI1 family
BCV50_08860	COG5583	Uncharacterized small protein (DUF2292)
BCV50_08875	COG0346	lactoylglutathione lyase activity
BCV50_08880	COG2329	Antibiotic biosynthesis monooxygenase
BCV50_08885	COG2323	membrane
BCV50_08890	COG1486	melibiose metabolic process
BCV50_08895	COG0395	ABC-type sugar transport system, permease component
BCV50_08900	COG4209	transmembrane transport
BCV50_08905	COG1653	transport
BCV50_08915	COG1874	Beta-galactosidase
BCV50_08920	COG2755	lipolytic protein G-D-S-L family
BCV50_08925	COG3401	FG-GAP repeat protein
BCV50_08930	COG3401	FG-GAP repeat protein
BCV50_08935	COG5578	integral membrane protein
BCV50_08945	COG2755	lipolytic protein G-D-S-L family
BCV50_08950	COG2207	Transcriptional regulator
BCV50_08955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BCV50_08960	COG0395	ABC-type sugar transport system, permease component
BCV50_08965	COG1175	transmembrane transport
BCV50_08970	COG1653	transport
BCV50_08975	COG4753	response regulator
BCV50_08975	COG2207	Transcriptional regulator
BCV50_08980	COG2972	Histidine kinase
BCV50_08985	COG5578	integral membrane protein
BCV50_08995	COG0454	-acetyltransferase
BCV50_09000	COG3546	catalase activity
BCV50_09015	COG1309	transcriptional regulator
BCV50_09020	COG2159	amidohydrolase
BCV50_09025	COG0702	epimerase
BCV50_09030	COG3631	Ketosteroid isomerase-related protein
BCV50_09035	COG1309	transcriptional regulator
BCV50_09045	COG0217	transcriptional regulatory protein
BCV50_09055	COG0457	Tetratricopeptide repeat
BCV50_09065	COG3391	amine dehydrogenase activity
BCV50_09070	COG5444	nuclease activity
BCV50_09085	COG0457	Tetratricopeptide repeat
BCV50_09100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCV50_09105	COG1597	lipid kinase activity
BCV50_09110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV50_09115	COG1309	transcriptional regulator
BCV50_09120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BCV50_09125	COG0154	amidase activity
BCV50_09130	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BCV50_09135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCV50_09140	COG1285	pathogenesis
BCV50_09150	COG1785	Belongs to the alkaline phosphatase family
BCV50_09155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCV50_09200	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCV50_09215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV50_09225	COG2814	Major facilitator Superfamily
BCV50_09230	COG4851	CamS sex pheromone cAM373 precursor
BCV50_09235	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BCV50_09240	COG0210	DNA helicase
BCV50_09245	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BCV50_09250	COG0069	glutamate synthase activity
BCV50_09255	COG4496	protein, YerC YecD
BCV50_09260	COG1470	cell adhesion involved in biofilm formation
BCV50_09265	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BCV50_09275	COG0531	amino acid
BCV50_09280	COG1522	sequence-specific DNA binding
BCV50_09285	COG0151	Belongs to the GarS family
BCV50_09290	COG0138	bifunctional purine biosynthesis protein purh
BCV50_09295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCV50_09300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCV50_09305	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCV50_09310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCV50_09315	COG0047	phosphoribosylformylglycinamidine synthase activity
BCV50_09320	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCV50_09325	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BCV50_09330	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCV50_09335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BCV50_09340	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCV50_09350	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BCV50_09360	COG3064	Membrane
BCV50_09365	COG2252	PERMEase
BCV50_09395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCV50_09395	COG0519	Catalyzes the synthesis of GMP from XMP
BCV50_09400	COG1305	Transglutaminase-like
BCV50_09405	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BCV50_09410	COG0714	Associated with various cellular activities
BCV50_09415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCV50_09425	COG1113	amino acid transport
BCV50_09430	COG2132	Multicopper oxidase
BCV50_09440	COG2267	carboxylic ester hydrolase activity
BCV50_09455	COG0823	Involved in the tonB-independent uptake of proteins
BCV50_09460	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BCV50_09465	COG1063	alcohol dehydrogenase
BCV50_09470	COG2814	Major facilitator Superfamily
BCV50_09480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV50_09485	COG2211	Major facilitator Superfamily
BCV50_09490	COG1063	alcohol dehydrogenase
BCV50_09495	COG0457	Tetratricopeptide repeat
BCV50_09525	COG0459	protein refolding
BCV50_09530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BCV50_09535	COG1266	CAAX protease self-immunity
BCV50_09545	COG0805	protein transport
BCV50_09550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCV50_09555	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BCV50_09560	COG0315	cyclic pyranopterin monophosphate synthase activity
BCV50_09565	COG0488	(ABC) transporter
BCV50_09570	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BCV50_09575	COG0456	acetyltransferase
BCV50_09580	COG1214	PFAM Peptidase M22, glycoprotease
BCV50_09585	COG0802	atpase or kinase
BCV50_09590	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BCV50_09635	COG4124	Belongs to the glycosyl hydrolase 26 family
BCV50_09640	COG1482	cell wall glycoprotein biosynthetic process
BCV50_09645	COG1940	carbohydrate kinase activity
BCV50_09650	COG2188	Transcriptional regulator
BCV50_09655	COG2723	6-phospho-beta-galactosidase activity
BCV50_09660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV50_09665	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCV50_09670	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV50_09675	COG2814	Major facilitator Superfamily
BCV50_09680	COG1388	LysM domain
BCV50_09685	COG1078	dGTPase activity
BCV50_09695	COG5646	InterPro IPR014922
BCV50_09700	COG1785	Belongs to the alkaline phosphatase family
BCV50_09710	COG1819	glycosyl
BCV50_09715	COG3858	chitin binding
BCV50_09715	COG1388	LysM domain
BCV50_09720	COG1802	Transcriptional regulator
BCV50_09725	COG0730	response to heat
BCV50_09730	COG2814	Major facilitator Superfamily
BCV50_09745	COG1396	sequence-specific DNA binding
BCV50_09750	COG1846	Transcriptional regulator
BCV50_09755	COG0778	Nitroreductase
BCV50_09760	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_09770	COG2409	Drug exporters of the RND superfamily
BCV50_09770	COG1033	growth of symbiont in host cell
BCV50_09775	COG1846	Transcriptional regulator
BCV50_09780	COG2318	DinB family
BCV50_09785	COG1113	amino acid transport
BCV50_09800	COG2814	Major facilitator Superfamily
BCV50_09805	COG1609	Transcriptional regulator
BCV50_09810	COG0673	inositol 2-dehydrogenase activity
BCV50_09815	COG0456	acetyltransferase
BCV50_09825	COG1309	transcriptional regulator
BCV50_09835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV50_09840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV50_09845	COG2259	Doxx family
BCV50_09850	COG0346	lactoylglutathione lyase activity
BCV50_09855	COG0778	Nitroreductase
BCV50_09860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCV50_09865	COG0789	Transcriptional regulator
BCV50_09865	COG4978	Transcriptional regulator
BCV50_09870	COG1811	Na channel or pump
BCV50_09875	COG0596	Alpha beta hydrolase
BCV50_09880	COG0110	maltose O-acetyltransferase activity
BCV50_09890	COG2409	Drug exporters of the RND superfamily
BCV50_09895	COG2197	response regulator
BCV50_09900	COG4585	Histidine kinase
BCV50_09910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV50_09915	COG0640	Transcriptional regulator
BCV50_09920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCV50_09925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV50_09930	COG0697	spore germination
BCV50_09935	COG0789	Transcriptional regulator
BCV50_09940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCV50_09945	COG0640	Transcriptional regulator
BCV50_09950	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCV50_09960	COG1309	transcriptional regulator
BCV50_09965	COG2814	Major facilitator Superfamily
BCV50_09970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCV50_09975	COG1733	regulation of RNA biosynthetic process
BCV50_09980	COG3545	Serine hydrolase
BCV50_09985	COG2030	dehydratase
BCV50_09990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV50_09995	COG0697	spore germination
BCV50_10010	COG1522	sequence-specific DNA binding
BCV50_10015	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BCV50_10025	COG1733	regulation of RNA biosynthetic process
BCV50_10030	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCV50_10040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCV50_10045	COG0745	RESPONSE REGULATOR receiver
BCV50_10050	COG5002	protein histidine kinase activity
BCV50_10060	COG0726	polysaccharide deacetylase
BCV50_10070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV50_10080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV50_10085	COG2814	Major facilitator Superfamily
BCV50_10090	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BCV50_10100	COG2207	Transcriptional regulator
BCV50_10100	COG3708	Transcriptional regulator
BCV50_10105	COG1329	Transcriptional regulator
BCV50_10110	COG1278	Cold shock
BCV50_10125	COG1476	TRANSCRIPTIONal
BCV50_10130	COG5444	nuclease activity
BCV50_10140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV50_10145	COG0583	DNA-binding transcription factor activity
BCV50_10190	COG3091	SprT-like family
BCV50_10200	COG2183	response to ionizing radiation
BCV50_10205	COG2208	phosphoserine phosphatase activity
BCV50_10210	COG1191	sigma factor activity
BCV50_10215	COG2172	sigma factor antagonist activity
BCV50_10220	COG1366	Belongs to the anti-sigma-factor antagonist family
BCV50_10225	COG2208	phosphoserine phosphatase activity
BCV50_10230	COG2172	sigma factor antagonist activity
BCV50_10235	COG1366	Belongs to the anti-sigma-factor antagonist family
BCV50_10240	COG1366	Belongs to the anti-sigma-factor antagonist family
BCV50_10245	COG2337	Toxic component of a toxin-antitoxin (TA) module
BCV50_10250	COG0864	Transcriptional regulator
BCV50_10255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCV50_10260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCV50_10265	COG0736	holo-[acyl-carrier-protein] synthase activity
BCV50_10270	COG0705	Rhomboid family
BCV50_10275	COG3428	Bacterial PH domain
BCV50_10280	COG3402	PFAM membrane-flanked domain
BCV50_10285	COG0513	Belongs to the DEAD box helicase family
BCV50_10295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCV50_10300	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCV50_10305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV50_10310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCV50_10325	COG1960	acyl-CoA dehydrogenase activity
BCV50_10335	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCV50_10340	COG1131	(ABC) transporter
BCV50_10345	COG1301	dicarboxylic acid transport
BCV50_10350	COG0628	permease
BCV50_10355	COG1301	dicarboxylic acid transport
BCV50_10360	COG4565	transcriptional regulatory protein
BCV50_10365	COG3290	protein histidine kinase activity
BCV50_10370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BCV50_10375	COG3546	catalase activity
BCV50_10380	COG2329	Antibiotic biosynthesis monooxygenase
BCV50_10385	COG0662	Cupin 2, conserved barrel domain protein
BCV50_10390	COG3729	General stress protein
BCV50_10395	COG2217	Heavy metal translocating P-type atpase
BCV50_10400	COG4876	unkown
BCV50_10405	COG2261	transglycosylase associated protein
BCV50_10410	COG1914	H( )-stimulated, divalent metal cation uptake system
BCV50_10425	COG0028	Belongs to the TPP enzyme family
BCV50_10430	COG0494	nUDIX hydrolase
BCV50_10435	COG0531	amino acid
BCV50_10445	COG1215	transferase activity, transferring glycosyl groups
BCV50_10450	COG5298	Protein conserved in bacteria
BCV50_10455	COG3706	GGDEF domain
BCV50_10460	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BCV50_10465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCV50_10465	COG0551	DNA topoisomerase type I activity
BCV50_10470	COG1522	sequence-specific DNA binding
BCV50_10475	COG2814	Major facilitator Superfamily
BCV50_10485	COG3871	stress protein (general stress protein 26)
BCV50_10490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV50_10495	COG1917	Cupin 2, conserved barrel domain protein
BCV50_10500	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_10505	COG2226	methyltransferase
BCV50_10510	COG0318	PFAM AMP-dependent synthetase and ligase
BCV50_10515	COG3711	transcriptional antiterminator
BCV50_10520	COG4989	oxidoreductase activity
BCV50_10525	COG0768	penicillin binding
BCV50_10530	COG2329	Antibiotic biosynthesis monooxygenase
BCV50_10540	COG2755	lipolytic protein G-D-S-L family
BCV50_10545	COG1414	Transcriptional regulator
BCV50_10550	COG1984	allophanate hydrolase subunit 2
BCV50_10555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BCV50_10560	COG4336	lyase activity
BCV50_10565	COG1914	H( )-stimulated, divalent metal cation uptake system
BCV50_10570	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BCV50_10575	COG0561	phosphatase activity
BCV50_10585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCV50_10590	COG0412	Dienelactone hydrolase
BCV50_10595	COG0473	3-isopropylmalate dehydrogenase activity
BCV50_10600	COG0246	Mannitol dehydrogenase
BCV50_10605	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV50_10610	COG2213	PTS system mannitol-specific
BCV50_10620	COG1349	DNA-binding transcription factor activity
BCV50_10625	COG1276	copper resistance
BCV50_10625	COG2372	response to copper ion
BCV50_10630	COG4549	nuclear export factor GLE1
BCV50_10635	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_10640	COG4975	Glucose uptake
BCV50_10645	COG1012	belongs to the aldehyde dehydrogenase family
BCV50_10650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCV50_10655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV50_10660	COG0640	Transcriptional regulator
BCV50_10665	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BCV50_10670	COG0778	Nitroreductase
BCV50_10675	COG1309	transcriptional regulator
BCV50_10680	COG2814	Major facilitator Superfamily
BCV50_10685	COG4607	ABC-type enterochelin transport system periplasmic component
BCV50_10690	COG4604	ABC transporter, ATP-binding protein
BCV50_10695	COG4605	iron ion homeostasis
BCV50_10700	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV50_10705	COG0527	aspartate kinase activity
BCV50_10720	COG0457	Tetratricopeptide repeat
BCV50_10725	COG3850	Histidine kinase
BCV50_10725	COG5002	protein histidine kinase activity
BCV50_10730	COG0745	RESPONSE REGULATOR receiver
BCV50_10735	COG0577	efflux transmembrane transporter activity
BCV50_10740	COG1136	(ABC) transporter
BCV50_10745	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCV50_10755	COG0697	spore germination
BCV50_10765	COG5434	Belongs to the glycosyl hydrolase 28 family
BCV50_10770	COG3104	oligopeptide transport
BCV50_10775	COG0596	Alpha beta hydrolase
BCV50_10790	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BCV50_10795	COG0163	prenyltransferase activity
BCV50_10800	COG0583	DNA-binding transcription factor activity
BCV50_10805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV50_10810	COG0765	amino acid transport
BCV50_10815	COG1126	abc transporter atp-binding protein
BCV50_10820	COG2364	Membrane
BCV50_10830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV50_10835	COG0697	spore germination
BCV50_10845	COG2814	Major facilitator Superfamily
BCV50_10850	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BCV50_10855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_10860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_10865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_10875	COG1733	regulation of RNA biosynthetic process
BCV50_10880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BCV50_10885	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BCV50_10890	COG3290	protein histidine kinase activity
BCV50_10890	COG0840	transmembrane signaling receptor activity
BCV50_10895	COG3209	COG3209 Rhs family protein
BCV50_10905	COG2723	6-phospho-beta-galactosidase activity
BCV50_10915	COG1714	RDD family
BCV50_10920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV50_10925	COG0765	amino acid transport
BCV50_10930	COG0523	cobalamin synthesis protein
BCV50_10940	COG1376	ErfK ybiS ycfS ynhG family protein
BCV50_10945	COG1469	GTP cyclohydrolase I activity
BCV50_10950	COG2223	nitrite transmembrane transporter activity
BCV50_10955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCV50_10960	COG0243	molybdopterin cofactor binding
BCV50_10965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCV50_10970	COG2146	nitrite reductase [NAD(P)H] activity
BCV50_10975	COG1587	Uroporphyrinogen-III synthase
BCV50_10975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCV50_10980	COG0492	ferredoxin-NADP+ reductase activity
BCV50_10985	COG2267	carboxylic ester hydrolase activity
BCV50_10990	COG0701	Predicted permease
BCV50_10995	COG3689	TIGRFAM TIGR03943 family protein
BCV50_11000	COG2508	Transcriptional regulator
BCV50_11005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCV50_11010	COG1012	belongs to the aldehyde dehydrogenase family
BCV50_11015	COG0506	proline dehydrogenase activity
BCV50_11020	COG3541	Predicted nucleotidyltransferase
BCV50_11025	COG3458	cephalosporin-C deacetylase activity
BCV50_11030	COG0583	DNA-binding transcription factor activity
BCV50_11035	COG2226	methyltransferase
BCV50_11040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCV50_11045	COG1660	Displays ATPase and GTPase activities
BCV50_11050	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCV50_11055	COG3665	Urea carboxylase-associated protein
BCV50_11060	COG1113	amino acid transport
BCV50_11065	COG3403	YqcI/YcgG family
BCV50_11070	COG1280	lysine exporter protein (LysE YggA)
BCV50_11075	COG1846	Transcriptional regulator
BCV50_11080	COG2814	Major facilitator Superfamily
BCV50_11085	COG1620	l-lactate permease
BCV50_11090	COG0039	L-malate dehydrogenase activity
BCV50_11095	COG0366	Alpha amylase catalytic
BCV50_11110	COG1288	antiporter activity
BCV50_11115	COG1473	amidohydrolase
BCV50_11120	COG2113	Glycine betaine
BCV50_11125	COG4176	ABC-type proline glycine betaine transport system permease component
BCV50_11130	COG0517	IMP dehydrogenase activity
BCV50_11130	COG4175	Glycine betaine
BCV50_11135	COG0640	Transcriptional regulator
BCV50_11140	COG2814	Major facilitator Superfamily
BCV50_11145	COG0477	Major facilitator Superfamily
BCV50_11150	COG3853	Toxic anion resistance protein (TelA)
BCV50_11160	COG0861	Integral membrane protein TerC family
BCV50_11165	COG2310	stress, protein
BCV50_11170	COG2310	stress, protein
BCV50_11175	COG2310	stress, protein
BCV50_11180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV50_11185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCV50_11190	COG1121	(ABC) transporter
BCV50_11195	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCV50_11200	COG0366	Alpha amylase catalytic
BCV50_11205	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_11210	COG0457	Tetratricopeptide repeat
BCV50_11215	COG1876	peptidase activity
BCV50_11220	COG1595	DNA-templated transcription, initiation
BCV50_11225	COG1595	DNA-templated transcription, initiation
BCV50_11235	COG0667	Aldo Keto reductase
BCV50_11240	COG1668	transmembrane transport
BCV50_11245	COG4555	ABC transporter
BCV50_11250	COG3279	Response regulator of the LytR AlgR family
BCV50_11255	COG3290	protein histidine kinase activity
BCV50_11260	COG3012	SEC-C Motif Domain Protein
BCV50_11260	COG1405	negative regulation of cell septum assembly
BCV50_11265	COG1714	RDD family
BCV50_11270	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BCV50_11275	COG0252	asparaginase activity
BCV50_11280	COG1309	transcriptional regulator
BCV50_11285	COG0477	Major facilitator Superfamily
BCV50_11290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCV50_11295	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BCV50_11300	COG0805	protein transport
BCV50_11305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCV50_11310	COG3540	Alkaline phosphatase
BCV50_11325	COG3773	Cell wall hydrolase
BCV50_11345	COG1131	(ABC) transporter
BCV50_11350	COG2205	protein histidine kinase activity
BCV50_11355	COG0745	RESPONSE REGULATOR receiver
BCV50_11360	COG0697	spore germination
BCV50_11370	COG3173	Aminoglycoside phosphotransferase
BCV50_11375	COG2721	sulfolactate sulfo-lyase activity
BCV50_11380	COG2186	Transcriptional regulator
BCV50_11385	COG4948	Mandelate Racemase Muconate Lactonizing
BCV50_11390	COG2271	Major facilitator Superfamily
BCV50_11395	COG1012	belongs to the aldehyde dehydrogenase family
BCV50_11400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCV50_11405	COG0784	Response regulator, receiver
BCV50_11410	COG4191	Histidine kinase
BCV50_11415	COG2066	Belongs to the glutaminase family
BCV50_11420	COG1115	amino acid carrier protein
BCV50_11430	COG2040	homocysteine
BCV50_11435	COG0833	amino acid
BCV50_11440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCV50_11455	COG0363	glucosamine-6-phosphate deaminase activity
BCV50_11460	COG1263	PTS System
BCV50_11460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_11460	COG2190	(PTS) system
BCV50_11465	COG1301	dicarboxylic acid transport
BCV50_11480	COG0688	phosphatidylethanolamine metabolic process
BCV50_11485	COG0586	Pfam SNARE associated Golgi protein
BCV50_11490	COG1183	phosphatidylcholine synthase activity
BCV50_11495	COG0596	Alpha beta hydrolase
BCV50_11505	COG3591	Belongs to the peptidase S1B family
BCV50_11510	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BCV50_11515	COG1917	Cupin 2, conserved barrel domain protein
BCV50_11515	COG2207	Transcriptional regulator
BCV50_11520	COG0697	spore germination
BCV50_11525	COG2271	Major facilitator Superfamily
BCV50_11530	COG0456	acetyltransferase
BCV50_11530	COG1846	Transcriptional regulator
BCV50_11540	COG2271	Major facilitator Superfamily
BCV50_11545	COG0584	glycerophosphoryl diester phosphodiesterase
BCV50_11550	COG1283	sodium-dependent phosphate transmembrane transporter activity
BCV50_11555	COG0531	amino acid
BCV50_11565	COG2124	cytochrome p450
BCV50_11570	COG2602	Beta-lactamase
BCV50_11585	COG1113	amino acid transport
BCV50_11600	COG0515	serine threonine protein kinase
BCV50_11610	COG0642	Histidine kinase
BCV50_11615	COG0745	RESPONSE REGULATOR receiver
BCV50_11620	COG0596	Alpha beta hydrolase
BCV50_11635	COG1413	lyase activity
BCV50_11640	COG2814	Major facilitator Superfamily
BCV50_11645	COG0640	Transcriptional regulator
BCV50_11650	COG5609	conserved protein (DUF2294)
BCV50_11660	COG0288	reversible hydration of carbon dioxide
BCV50_11665	COG3002	Belongs to the UPF0753 family
BCV50_11670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCV50_11675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCV50_11680	COG2169	Transcriptional regulator
BCV50_11690	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCV50_11705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV50_11710	COG4856	YbbR-like protein
BCV50_11715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BCV50_11720	COG5662	AntiSigma factor
BCV50_11725	COG1595	DNA-templated transcription, initiation
BCV50_11755	COG1683	Conserved Protein
BCV50_11760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV50_11765	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BCV50_11770	COG1737	Transcriptional regulator
BCV50_11775	COG1263	PTS System
BCV50_11775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_11780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV50_11785	COG1472	Belongs to the glycosyl hydrolase 3 family
BCV50_11790	COG3876	Protein conserved in bacteria
BCV50_11795	COG2207	Transcriptional regulator
BCV50_11795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCV50_11800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCV50_11805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV50_11810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV50_11815	COG2819	hydrolase of the alpha beta superfamily
BCV50_11820	COG0385	Bile acid
BCV50_11825	COG0659	secondary active sulfate transmembrane transporter activity
BCV50_11830	COG1063	alcohol dehydrogenase
BCV50_11840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCV50_11845	COG0738	Major facilitator superfamily
BCV50_11925	COG0726	polysaccharide deacetylase
BCV50_11930	COG2194	sulfuric ester hydrolase activity
BCV50_11940	COG0489	protein tyrosine kinase activity
BCV50_11945	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV50_11955	COG2226	methyltransferase
BCV50_11965	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCV50_11970	COG0101	tRNA pseudouridine synthase activity
BCV50_11975	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BCV50_11980	COG1122	ATPase activity
BCV50_11985	COG1122	ATPase activity
BCV50_11990	COG0203	ribosomal protein L17
BCV50_11995	COG0202	RNA polymerase activity
BCV50_12000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BCV50_12010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BCV50_12015	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BCV50_12020	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BCV50_12025	COG0024	Methionine aminopeptidase
BCV50_12030	COG0563	adenylate kinase activity
BCV50_12035	COG0201	protein transport
BCV50_12040	COG0200	Binds to the 23S rRNA
BCV50_12045	COG1841	ribosomal large subunit assembly
BCV50_12055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BCV50_12060	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BCV50_12065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BCV50_12075	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BCV50_12085	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BCV50_12090	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCV50_12095	COG0255	Belongs to the universal ribosomal protein uL29 family
BCV50_12100	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BCV50_12105	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BCV50_12110	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BCV50_12115	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCV50_12120	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BCV50_12125	COG0089	rRNA binding
BCV50_12135	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BCV50_12140	COG0051	transcription antitermination factor activity, RNA binding
BCV50_12145	COG0596	Alpha beta hydrolase
BCV50_12150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCV50_12155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCV50_12160	COG0049	tRNA binding
BCV50_12165	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BCV50_12170	COG1358	cellular component organization or biogenesis
BCV50_12175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BCV50_12180	COG0085	RNA polymerase activity
BCV50_12185	COG2813	Specifically methylates the guanine in position
BCV50_12190	COG0222	ribosome binding
BCV50_12195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCV50_12200	COG0081	regulation of translation
BCV50_12205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCV50_12210	COG0250	Participates in transcription elongation, termination and antitermination
BCV50_12215	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCV50_12220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCV50_12225	COG1595	DNA-templated transcription, initiation
BCV50_12230	COG3688	RNA-binding protein containing a PIN domain
BCV50_12235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV50_12240	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BCV50_12245	COG0215	cysteine-tRNA ligase activity
BCV50_12250	COG1045	serine acetyltransferase
BCV50_12260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCV50_12265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCV50_12270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BCV50_12275	COG4956	integral membrane protein (PIN domain superfamily)
BCV50_12280	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BCV50_12285	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BCV50_12290	COG0542	response to heat
BCV50_12295	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BCV50_12300	COG3880	PFAM UvrB UvrC protein
BCV50_12305	COG4463	regulation of RNA biosynthetic process
BCV50_12390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BCV50_12395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCV50_12400	COG1396	sequence-specific DNA binding
BCV50_12405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCV50_12410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCV50_12415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCV50_12420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCV50_12425	COG0512	Glutamine amidotransferase of anthranilate synthase
BCV50_12430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCV50_12435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCV50_12440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV50_12445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BCV50_12450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BCV50_12455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCV50_12465	COG0037	tRNA processing
BCV50_12470	COG0515	serine threonine protein kinase
BCV50_12475	COG2304	oxidoreductase activity
BCV50_12480	COG2208	phosphoserine phosphatase activity
BCV50_12495	COG1098	S1 RNA binding domain
BCV50_12500	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BCV50_12515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCV50_12520	COG3956	TIGRFAM MazG family protein
BCV50_12525	COG2244	polysaccharide biosynthetic process
BCV50_12530	COG2002	toxin-antitoxin pair type II binding
BCV50_12535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCV50_12545	COG0193	aminoacyl-tRNA hydrolase activity
BCV50_12550	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BCV50_12555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BCV50_12560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCV50_12565	COG2088	sporulation resulting in formation of a cellular spore
BCV50_12570	COG0251	oxidation-reduction process
BCV50_12575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCV50_12580	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BCV50_12590	COG4466	Protein conserved in bacteria
BCV50_12600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BCV50_12605	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BCV50_12610	COG3584	3D domain protein
BCV50_12610	COG3583	domain protein
BCV50_12615	COG0084	hydrolase, TatD family'
BCV50_12620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV50_12620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV50_12625	COG2002	toxin-antitoxin pair type II binding
BCV50_12630	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCV50_12635	COG2827	Endonuclease containing a URI domain
BCV50_12640	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BCV50_12645	COG4467	Involved in initiation control of chromosome replication
BCV50_12650	COG1774	PSP1 C-terminal conserved region
BCV50_12655	COG0470	DNA polymerase III
BCV50_12660	COG1728	Protein conserved in bacteria
BCV50_12665	COG3870	Protein conserved in bacteria
BCV50_12670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BCV50_12675	COG1982	Orn Lys Arg decarboxylase major
BCV50_12680	COG3853	Toxic anion resistance protein (TelA)
BCV50_12685	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BCV50_12720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BCV50_12725	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BCV50_12730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCV50_12740	COG0590	tRNA wobble adenosine to inosine editing
BCV50_12745	COG1335	isochorismatase
BCV50_12750	COG1388	LysM domain
BCV50_12750	COG3858	chitin binding
BCV50_12755	COG1428	Deoxynucleoside kinase
BCV50_12760	COG1428	Deoxynucleoside kinase
BCV50_12770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BCV50_12775	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BCV50_12785	COG1686	Belongs to the peptidase S11 family
BCV50_12790	COG0516	GMP reductase activity
BCV50_12790	COG0517	IMP dehydrogenase activity
BCV50_12815	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCV50_12820	COG0187	DNA topoisomerase II activity
BCV50_12830	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCV50_12835	COG2501	S4 domain
BCV50_12840	COG0592	DNA-directed DNA polymerase activity
BCV50_12845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCV50_12850	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BCV50_12855	COG0594	ribonuclease P activity
BCV50_12860	COG0706	membrane insertase activity
BCV50_12865	COG1847	R3H domain protein
BCV50_12870	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCV50_12875	COG0445	tRNA wobble uridine modification
BCV50_12880	COG0357	Ribosomal RNA small subunit methyltransferase G
BCV50_12885	COG1475	DNA binding
BCV50_12895	COG1192	Involved in chromosome partitioning
BCV50_12900	COG1475	DNA binding
BCV50_12910	COG3949	Membrane
BCV50_12915	COG4481	Protein conserved in bacteria
BCV50_12920	COG0243	molybdopterin cofactor binding
BCV50_12925	COG0012	GTP binding
BCV50_12930	COG0360	Binds together with S18 to 16S ribosomal RNA
BCV50_12935	COG0629	single-stranded DNA binding
BCV50_12940	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCV50_12945	COG0708	Exodeoxyribonuclease III
BCV50_12950	COG1609	Transcriptional regulator
BCV50_12955	COG0346	lactoylglutathione lyase activity
BCV50_12960	COG0477	Major facilitator Superfamily
BCV50_12960	COG2814	Major facilitator Superfamily
BCV50_12965	COG1266	CAAX protease self-immunity
BCV50_12970	COG1331	Highly conserved protein containing a thioredoxin domain
BCV50_12975	COG0697	spore germination
BCV50_12980	COG0789	Transcriptional regulator
BCV50_12990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV50_12995	COG1846	Transcriptional regulator
BCV50_13005	COG1309	transcriptional regulator
BCV50_13025	COG2364	Membrane
BCV50_13030	COG2153	protein acetylation
BCV50_13035	COG1846	Transcriptional regulator
BCV50_13040	COG1733	regulation of RNA biosynthetic process
BCV50_13045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV50_13060	COG0583	DNA-binding transcription factor activity
BCV50_13070	COG2153	protein acetylation
BCV50_13075	COG0583	DNA-binding transcription factor activity
BCV50_13080	COG2814	Major facilitator Superfamily
BCV50_13085	COG1357	PFAM Pentapeptide repeats (8 copies)
BCV50_13090	COG4319	ketosteroid isomerase
BCV50_13100	COG2271	Major facilitator Superfamily
BCV50_13115	COG1227	inorganic diphosphatase activity
BCV50_13120	COG1733	regulation of RNA biosynthetic process
BCV50_13125	COG5577	PFAM Coat F domain
BCV50_13135	COG4241	membrane
BCV50_13140	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BCV50_13145	COG0359	binds to the 23S rRNA
BCV50_13150	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BCV50_13155	COG2807	transmembrane transport
BCV50_13160	COG3093	addiction module antidote protein HigA
BCV50_13180	COG0305	Participates in initiation and elongation during chromosome replication
BCV50_13185	COG0346	lactoylglutathione lyase activity
BCV50_13215	COG0745	RESPONSE REGULATOR receiver
BCV50_13220	COG5002	protein histidine kinase activity
BCV50_13225	COG4863	YycH protein
BCV50_13230	COG4853	Protein conserved in bacteria
BCV50_13235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BCV50_13240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV50_13255	COG3829	transcription factor binding
BCV50_13260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCV50_13265	COG0833	amino acid
BCV50_13270	COG0010	Belongs to the arginase family
BCV50_13280	COG0457	Tetratricopeptide repeat
BCV50_13285	COG0456	acetyltransferase
BCV50_13290	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BCV50_13310	COG1063	alcohol dehydrogenase
BCV50_13325	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BCV50_13330	COG1476	TRANSCRIPTIONal
BCV50_13340	COG1131	(ABC) transporter
BCV50_13350	COG1073	alpha beta
BCV50_13355	COG2205	protein histidine kinase activity
BCV50_13395	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BCV50_13415	COG3634	alkyl hydroperoxide reductase activity
BCV50_13420	COG0450	alkyl hydroperoxide reductase
BCV50_13425	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BCV50_13430	COG2610	gluconate transmembrane transporter activity
BCV50_13435	COG1070	Carbohydrate kinase
BCV50_13440	COG1802	Transcriptional regulator
BCV50_13445	COG1929	Belongs to the glycerate kinase type-1 family
BCV50_13450	COG5039	Polysaccharide pyruvyl transferase
BCV50_13455	COG1346	cytolysis
BCV50_13460	COG1380	Effector of murein hydrolase LrgA
BCV50_13465	COG1846	Transcriptional regulator
BCV50_13470	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_13475	COG1309	transcriptional regulator
BCV50_13480	COG1917	Cupin 2, conserved barrel domain protein
BCV50_13485	COG2311	Membrane
BCV50_13490	COG1714	RDD family
BCV50_13500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV50_13510	COG1012	belongs to the aldehyde dehydrogenase family
BCV50_13515	COG1309	transcriptional regulator
BCV50_13520	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_13530	COG0326	Molecular chaperone. Has ATPase activity
BCV50_13535	COG2814	Major facilitator Superfamily
BCV50_13560	COG0667	Aldo Keto reductase
BCV50_13565	COG1349	DNA-binding transcription factor activity
BCV50_13570	COG1012	belongs to the aldehyde dehydrogenase family
BCV50_13580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV50_13585	COG3962	Belongs to the TPP enzyme family
BCV50_13590	COG1082	Xylose isomerase domain protein TIM barrel
BCV50_13595	COG2814	Major facilitator Superfamily
BCV50_13600	COG0673	inositol 2-dehydrogenase activity
BCV50_13605	COG1082	Xylose isomerase domain protein TIM barrel
BCV50_13610	COG1082	Xylose isomerase domain protein TIM barrel
BCV50_13615	COG0191	fructose-bisphosphate aldolase activity
BCV50_13620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCV50_13630	COG0745	RESPONSE REGULATOR receiver
BCV50_13635	COG2205	protein histidine kinase activity
BCV50_13640	COG1136	(ABC) transporter
BCV50_13645	COG0577	efflux transmembrane transporter activity
BCV50_13650	COG5294	Protein conserved in bacteria
BCV50_13675	COG0561	phosphatase activity
BCV50_13680	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BCV50_13695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV50_13700	COG0765	amino acid transport
BCV50_13705	COG1126	abc transporter atp-binding protein
BCV50_13715	COG2079	MmgE PrpD family protein
BCV50_13720	COG3192	ethanolamine utilization protein
BCV50_13730	COG2390	Transcriptional regulator
BCV50_13735	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BCV50_13740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCV50_13745	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BCV50_13750	COG0833	amino acid
BCV50_13755	COG0010	Belongs to the arginase family
BCV50_13760	COG1228	amidohydrolase
BCV50_13765	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BCV50_13770	COG2986	histidine ammonia-lyase
BCV50_13785	COG3507	Belongs to the glycosyl hydrolase 43 family
BCV50_13800	COG5444	nuclease activity
BCV50_13830	COG2190	(PTS) system
BCV50_13830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_13830	COG1263	PTS System
BCV50_13835	COG2723	6-phospho-beta-galactosidase activity
BCV50_13840	COG0589	response to stress
BCV50_13845	COG0861	Integral membrane protein TerC family
BCV50_13855	COG0697	spore germination
BCV50_13925	COG3401	FG-GAP repeat protein
BCV50_13925	COG2755	lipolytic protein G-D-S-L family
BCV50_13930	COG0513	Belongs to the DEAD box helicase family
BCV50_13935	COG2270	Major facilitator Superfamily
BCV50_13945	COG3711	transcriptional antiterminator
BCV50_13950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_13950	COG1263	PTS System
BCV50_13950	COG2190	(PTS) system
BCV50_13955	COG2723	6-phospho-beta-galactosidase activity
BCV50_13960	COG2273	Hydrolase Family 16
BCV50_13965	COG2323	membrane
BCV50_13970	COG2851	Citrate transporter
BCV50_13975	COG0693	protein deglycase activity
BCV50_13975	COG0753	catalase activity
BCV50_13990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCV50_13995	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_14000	COG0500	methyltransferase
BCV50_14010	COG2610	gluconate transmembrane transporter activity
BCV50_14015	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BCV50_14020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BCV50_14025	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_14030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCV50_14035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCV50_14040	COG4894	glucomannan catabolic process
BCV50_14055	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCV50_14065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCV50_14075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCV50_14080	COG1012	belongs to the aldehyde dehydrogenase family
BCV50_14085	COG2508	Transcriptional regulator
BCV50_14090	COG3842	ATPase activity
BCV50_14100	COG0726	polysaccharide deacetylase
BCV50_14110	COG3493	citrate carrier protein
BCV50_14115	COG1271	oxidase subunit
BCV50_14120	COG1294	oxidase, subunit
BCV50_14125	COG4988	ABC transporter
BCV50_14130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BCV50_14135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BCV50_14140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCV50_14145	COG1595	DNA-templated transcription, initiation
BCV50_14165	COG1131	(ABC) transporter
BCV50_14170	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCV50_14175	COG2814	Major facilitator Superfamily
BCV50_14180	COG0753	catalase activity
BCV50_14185	COG2094	Belongs to the DNA glycosylase MPG family
BCV50_14195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV50_14195	COG3711	transcriptional antiterminator
BCV50_14200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV50_14205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV50_14210	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCV50_14215	COG1486	melibiose metabolic process
BCV50_14220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCV50_14225	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BCV50_14230	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BCV50_14235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCV50_14240	COG1696	Membrane protein involved in D-alanine export
BCV50_14245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_14260	COG1575	Belongs to the MenA family. Type 1 subfamily
BCV50_14265	COG2357	RelA SpoT domain protein
BCV50_14270	COG2814	Major facilitator Superfamily
BCV50_14285	COG2234	aminopeptidase activity
BCV50_14290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCV50_14295	COG1846	Transcriptional regulator
BCV50_14300	COG5522	Integral membrane protein (intg_mem_TP0381)
BCV50_14305	COG1442	glycosyl transferase family 8
BCV50_14310	COG3711	transcriptional antiterminator
BCV50_14315	COG1263	PTS System
BCV50_14315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_14320	COG1404	Belongs to the peptidase S8 family
BCV50_14325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV50_14330	COG0346	lactoylglutathione lyase activity
BCV50_14335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCV50_14340	COG4895	conserved protein (DUF2196)
BCV50_14345	COG2814	Major facilitator Superfamily
BCV50_14350	COG1346	cytolysis
BCV50_14355	COG1380	Effector of murein hydrolase LrgA
BCV50_14360	COG0583	DNA-binding transcription factor activity
BCV50_14365	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BCV50_14370	COG0352	thiamine-phosphate diphosphorylase activity
BCV50_14375	COG0672	)-iron permease
BCV50_14380	COG2822	iron ion transport
BCV50_14385	COG2837	iron assimilation
BCV50_14390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCV50_14395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCV50_14400	COG3162	membrane
BCV50_14410	COG1309	transcriptional regulator
BCV50_14415	COG2246	polysaccharide biosynthetic process
BCV50_14420	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BCV50_14425	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BCV50_14430	COG2261	transglycosylase associated protein
BCV50_14435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCV50_14460	COG0772	Belongs to the SEDS family
BCV50_14465	COG0778	Nitroreductase
BCV50_14470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV50_14475	COG1404	Belongs to the peptidase S8 family
BCV50_14485	COG3711	transcriptional antiterminator
BCV50_14490	COG2116	formate transmembrane transporter activity
BCV50_14495	COG1263	PTS System
BCV50_14495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_14500	COG1621	beta-fructofuranosidase activity
BCV50_14515	COG0351	phosphomethylpyrimidine kinase
BCV50_14520	COG1695	Transcriptional regulator
BCV50_14535	COG1216	Glycosyl transferase, family 2
BCV50_14540	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCV50_14555	COG2233	PERMEase
BCV50_14560	COG2363	Small membrane protein
BCV50_14575	COG0463	Glycosyl transferase, family 2
BCV50_14580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BCV50_14585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCV50_14585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCV50_14590	COG0456	acetyltransferase
BCV50_14600	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BCV50_14605	COG1088	dTDP-glucose 4,6-dehydratase activity
BCV50_14610	COG1091	dTDP-4-dehydrorhamnose reductase activity
BCV50_14615	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BCV50_14625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCV50_14635	COG1012	belongs to the aldehyde dehydrogenase family
BCV50_14640	COG4187	Peptidase family M20/M25/M40
BCV50_14645	COG0833	amino acid
BCV50_14650	COG2814	Major facilitator Superfamily
BCV50_14655	COG0077	Prephenate dehydratase
BCV50_14660	COG1917	Cupin 2, conserved barrel domain protein
BCV50_14665	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_14670	COG0151	Belongs to the GarS family
BCV50_14675	COG2814	Major facilitator Superfamily
BCV50_14680	COG0436	Aminotransferase
BCV50_14685	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_14695	COG0280	phosphate acetyltransferase
BCV50_14700	COG0583	DNA-binding transcription factor activity
BCV50_14705	COG0095	Lipoate-protein ligase
BCV50_14710	COG0697	spore germination
BCV50_14720	COG4844	belongs to the
BCV50_14725	COG1078	dGTPase activity
BCV50_14730	COG3465	dGTPase activity
BCV50_14735	COG1959	2 iron, 2 sulfur cluster binding
BCV50_14740	COG0477	Major facilitator Superfamily
BCV50_14750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCV50_14755	COG1846	Transcriptional regulator
BCV50_14760	COG1942	4-Oxalocrotonate Tautomerase
BCV50_14765	COG1994	Peptidase M50
BCV50_14780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV50_14785	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BCV50_14790	COG0010	Belongs to the arginase family
BCV50_14800	COG1131	(ABC) transporter
BCV50_14830	COG0457	Tetratricopeptide repeat
BCV50_14840	COG3391	amine dehydrogenase activity
BCV50_14845	COG3391	amine dehydrogenase activity
BCV50_14860	COG0612	Peptidase, M16
BCV50_14870	COG1131	(ABC) transporter
BCV50_14880	COG0535	radical SAM domain protein
BCV50_14890	COG4506	Protein conserved in bacteria
BCV50_14895	COG0018	arginyl-trna synthetase
BCV50_14900	COG2223	nitrite transmembrane transporter activity
BCV50_14905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV50_14915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV50_14920	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCV50_14925	COG1140	nitrate reductase beta subunit
BCV50_14930	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BCV50_14935	COG2181	nitrate reductase activity
BCV50_14945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV50_14950	COG1132	(ABC) transporter
BCV50_14965	COG4294	response to UV
BCV50_14970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV50_14975	COG2181	nitrate reductase activity
BCV50_14975	COG0247	lactate metabolic process
BCV50_14980	COG1960	acyl-CoA dehydrogenase activity
BCV50_14985	COG3343	RNA polymerase activity
BCV50_14990	COG0504	CTP synthase activity
BCV50_14995	COG4821	SIS domain
BCV50_15000	COG2204	response regulator
BCV50_15005	COG0191	fructose-bisphosphate aldolase activity
BCV50_15010	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCV50_15015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCV50_15020	COG1494	fructose-1,6-bisphosphatase
BCV50_15030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCV50_15035	COG0254	rRNA binding
BCV50_15040	COG1435	thymidine kinase activity
BCV50_15045	COG0281	malic enzyme
BCV50_15050	COG0679	Auxin Efflux Carrier
BCV50_15055	COG0789	Transcriptional regulator
BCV50_15060	COG0346	lactoylglutathione lyase activity
BCV50_15065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCV50_15070	COG2890	protein-(glutamine-N5) methyltransferase activity
BCV50_15090	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BCV50_15095	COG0009	L-threonylcarbamoyladenylate synthase
BCV50_15100	COG1971	Probably functions as a manganese efflux pump
BCV50_15105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCV50_15110	COG0698	ribose 5-phosphate isomerase
BCV50_15115	COG4475	Protein of unknown function (DUF436)
BCV50_15120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCV50_15125	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BCV50_15135	COG0356	it plays a direct role in the translocation of protons across the membrane
BCV50_15140	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCV50_15150	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BCV50_15155	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCV50_15160	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BCV50_15165	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BCV50_15170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BCV50_15185	COG4836	Membrane
BCV50_15195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCV50_15200	COG2385	sporulation resulting in formation of a cellular spore
BCV50_15205	COG2304	oxidoreductase activity
BCV50_15215	COG2304	oxidoreductase activity
BCV50_15225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BCV50_15230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BCV50_15235	COG0457	Tetratricopeptide repeat
BCV50_15240	COG1994	Peptidase M50
BCV50_15245	COG3237	CsbD-like
BCV50_15255	COG0559	Belongs to the binding-protein-dependent transport system permease family
BCV50_15275	COG0831	urea catabolic process
BCV50_15280	COG0832	Belongs to the urease beta subunit family
BCV50_15285	COG0804	urea catabolic process
BCV50_15290	COG1959	2 iron, 2 sulfur cluster binding
BCV50_15295	COG2910	NAD(P)H-binding
BCV50_15305	COG0789	Transcriptional regulator
BCV50_15310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV50_15320	COG2089	acid synthase
BCV50_15335	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BCV50_15340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCV50_15345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV50_15350	COG1086	Polysaccharide biosynthesis protein
BCV50_15360	COG1247	-acetyltransferase
BCV50_15365	COG0739	heme binding
BCV50_15375	COG0671	phosphoesterase, PA-phosphatase related
BCV50_15380	COG0347	Belongs to the P(II) protein family
BCV50_15385	COG0004	ammonium transporteR
BCV50_15395	COG1335	isochorismatase
BCV50_15400	COG0477	Major facilitator Superfamily
BCV50_15405	COG1953	Uracil, thiamine, allantoin
BCV50_15410	COG3420	alginic acid biosynthetic process
BCV50_15415	COG2814	Major facilitator Superfamily
BCV50_15420	COG1846	Transcriptional regulator
BCV50_15425	COG1609	Transcriptional regulator
BCV50_15430	COG1077	Cell shape determining protein MreB Mrl
BCV50_15435	COG4786	Flagellar basal body rod
BCV50_15440	COG4786	Flagellar basal body rod
BCV50_15445	COG0457	Tetratricopeptide repeat
BCV50_15450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCV50_15455	COG1970	mechanosensitive ion channel activity
BCV50_15460	COG0745	RESPONSE REGULATOR receiver
BCV50_15460	COG2972	Histidine kinase
BCV50_15465	COG3279	Response regulator of the LytR AlgR family
BCV50_15475	COG3764	Sortase (surface protein transpeptidase)
BCV50_15480	COG2602	Beta-lactamase
BCV50_15495	COG0629	single-stranded DNA binding
BCV50_15500	COG1349	DNA-binding transcription factor activity
BCV50_15505	COG0561	phosphatase activity
BCV50_15510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCV50_15515	COG4715	Zinc finger, swim domain protein
BCV50_15525	COG3944	biosynthesis protein
BCV50_15530	COG0489	protein tyrosine kinase activity
BCV50_15535	COG4464	protein tyrosine phosphatase activity
BCV50_15540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCV50_15555	COG5444	nuclease activity
BCV50_15585	COG0583	DNA-binding transcription factor activity
BCV50_15590	COG0655	NAD(P)H dehydrogenase (quinone) activity
BCV50_15600	COG2059	Chromate
BCV50_15605	COG2059	Chromate
BCV50_15610	COG1522	sequence-specific DNA binding
BCV50_15615	COG0405	Gamma-glutamyltransferase
BCV50_15625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCV50_15635	COG5337	Spore coat protein CotH
BCV50_15640	COG0583	DNA-binding transcription factor activity
BCV50_15645	COG0028	Belongs to the TPP enzyme family
BCV50_15650	COG3527	Alpha-acetolactate decarboxylase
BCV50_15655	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCV50_15665	COG3103	Sh3 type 3 domain protein
BCV50_15670	COG1879	ABC-type sugar transport system periplasmic component
BCV50_15675	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV50_15680	COG1129	ABC transporter
BCV50_15685	COG1869	D-ribose catabolic process
BCV50_15690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV50_15695	COG1609	Transcriptional regulator
BCV50_15700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCV50_15710	COG2843	Capsule synthesis protein
BCV50_15720	COG0791	NLP P60 protein
BCV50_15725	COG0561	phosphatase activity
BCV50_15730	COG1316	TRANSCRIPTIONal
BCV50_15735	COG2814	Major facilitator Superfamily
BCV50_15745	COG0814	amino acid
BCV50_15750	COG0697	spore germination
BCV50_15760	COG1482	cell wall glycoprotein biosynthetic process
BCV50_15765	COG4193	domain, Protein
BCV50_15810	COG0463	Glycosyl transferase, family 2
BCV50_15815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BCV50_15815	COG1215	transferase activity, transferring glycosyl groups
BCV50_15820	COG1682	transport, permease protein
BCV50_15825	COG1134	teichoic acid transport
BCV50_15830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCV50_15850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BCV50_15855	COG1316	TRANSCRIPTIONal
BCV50_15865	COG2247	cell wall binding repeat
BCV50_15865	COG2385	sporulation resulting in formation of a cellular spore
BCV50_15870	COG2247	cell wall binding repeat
BCV50_15870	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV50_15885	COG2244	polysaccharide biosynthetic process
BCV50_15890	COG0438	transferase activity, transferring glycosyl groups
BCV50_15890	COG0297	glycogen (starch) synthase activity
BCV50_15895	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCV50_15900	COG3307	-O-antigen
BCV50_15905	COG3206	protein involved in exopolysaccharide biosynthesis
BCV50_15910	COG1215	transferase activity, transferring glycosyl groups
BCV50_15915	COG0438	transferase activity, transferring glycosyl groups
BCV50_15920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCV50_15925	COG1316	TRANSCRIPTIONal
BCV50_15930	COG1739	Uncharacterized protein family UPF0029
BCV50_15935	COG4585	Histidine kinase
BCV50_15940	COG2197	response regulator
BCV50_15945	COG1307	EDD domain protein, DegV family
BCV50_15950	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BCV50_15960	COG1040	competence protein
BCV50_15970	COG2747	anti-sigma28 factor FlgM
BCV50_15975	COG3418	PFAM FlgN family protein
BCV50_15980	COG4786	Flagellar basal body rod
BCV50_15980	COG1256	bacterial-type flagellum assembly
BCV50_15985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCV50_15995	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BCV50_16000	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BCV50_16005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCV50_16010	COG1334	flagellar protein FlaG
BCV50_16015	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BCV50_16020	COG1516	flagellar protein fliS
BCV50_16035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BCV50_16040	COG0653	protein targeting
BCV50_16045	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCV50_16050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCV50_16055	COG2010	Cytochrome c
BCV50_16060	COG2884	Cell division ATP-binding protein ftsE
BCV50_16065	COG2177	Part of the ABC transporter FtsEX involved in
BCV50_16070	COG0793	Belongs to the peptidase S41A family
BCV50_16070	COG3409	Peptidoglycan-binding domain 1 protein
BCV50_16080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV50_16085	COG2814	Major facilitator Superfamily
BCV50_16090	COG1309	transcriptional regulator
BCV50_16095	COG3848	Pyruvate phosphate dikinase
BCV50_16095	COG0574	Belongs to the PEP-utilizing enzyme family
BCV50_16105	COG4897	Protein conserved in bacteria
BCV50_16110	COG0556	nucleotide-excision repair
BCV50_16115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCV50_16120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCV50_16135	COG3595	metallopeptidase activity
BCV50_16140	COG1983	PspC domain protein
BCV50_16145	COG1950	PFAM Membrane protein of
BCV50_16150	COG2814	Major facilitator Superfamily
BCV50_16155	COG1846	Transcriptional regulator
BCV50_16160	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BCV50_16170	COG0363	glucosamine-6-phosphate deaminase activity
BCV50_16175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCV50_16180	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BCV50_16185	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BCV50_16190	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCV50_16195	COG0546	phosphoglycolate phosphatase activity
BCV50_16200	COG0110	maltose O-acetyltransferase activity
BCV50_16205	COG5297	Belongs to the glycosyl hydrolase family 6
BCV50_16210	COG4990	cell redox homeostasis
BCV50_16215	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BCV50_16220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BCV50_16225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BCV50_16230	COG0131	Imidazoleglycerol-phosphate dehydratase
BCV50_16235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BCV50_16240	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BCV50_16245	COG0107	imidazoleglycerol-phosphate synthase activity
BCV50_16250	COG0140	phosphoribosyl-ATP diphosphatase activity
BCV50_16250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BCV50_16270	COG1132	(ABC) transporter
BCV50_16275	COG0457	Tetratricopeptide repeat
BCV50_16280	COG3883	PFAM NLP P60 protein
BCV50_16280	COG0791	NLP P60 protein
BCV50_16285	COG0492	ferredoxin-NADP+ reductase activity
BCV50_16290	COG1051	belongs to the nudix hydrolase family
BCV50_16295	COG1660	Displays ATPase and GTPase activities
BCV50_16300	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BCV50_16305	COG1481	regulation of sporulation
BCV50_16310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV50_16315	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BCV50_16325	COG0745	RESPONSE REGULATOR receiver
BCV50_16330	COG5002	protein histidine kinase activity
BCV50_16335	COG1136	(ABC) transporter
BCV50_16340	COG0577	efflux transmembrane transporter activity
BCV50_16345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCV50_16350	COG0288	reversible hydration of carbon dioxide
BCV50_16355	COG0659	secondary active sulfate transmembrane transporter activity
BCV50_16360	COG1694	Mazg nucleotide pyrophosphohydrolase
BCV50_16365	COG1611	Belongs to the LOG family
BCV50_16370	COG1609	Transcriptional regulator
BCV50_16375	COG0366	Alpha amylase catalytic
BCV50_16380	COG2182	Extracellular solute-binding protein
BCV50_16385	COG1175	transmembrane transport
BCV50_16390	COG3833	ABC-type maltose transport systems, permease component
BCV50_16395	COG5521	maltodextrose utilization protein MalA
BCV50_16400	COG1554	hydrolase, family 65, central catalytic
BCV50_16405	COG0366	Alpha amylase catalytic
BCV50_16410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV50_16430	COG2076	Multidrug Resistance protein
BCV50_16435	COG2076	Multidrug Resistance protein
BCV50_16440	COG1309	transcriptional regulator
BCV50_16445	COG0531	amino acid
BCV50_16450	COG1621	beta-fructofuranosidase activity
BCV50_16455	COG1621	beta-fructofuranosidase activity
BCV50_16465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV50_16470	COG1794	racemase activity, acting on amino acids and derivatives
BCV50_16480	COG3479	Phenolic acid decarboxylase
BCV50_16490	COG2272	Belongs to the type-B carboxylesterase lipase family
BCV50_16495	COG1396	sequence-specific DNA binding
BCV50_16500	COG3944	biosynthesis protein
BCV50_16505	COG0489	protein tyrosine kinase activity
BCV50_16515	COG0438	transferase activity, transferring glycosyl groups
BCV50_16520	COG1215	transferase activity, transferring glycosyl groups
BCV50_16525	COG0438	transferase activity, transferring glycosyl groups
BCV50_16535	COG1216	Glycosyl transferase, family 2
BCV50_16540	COG5039	Polysaccharide pyruvyl transferase
BCV50_16545	COG1216	Glycosyl transferase, family 2
BCV50_16550	COG2244	polysaccharide biosynthetic process
BCV50_16555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BCV50_16560	COG0110	maltose O-acetyltransferase activity
BCV50_16565	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCV50_16570	COG5039	Polysaccharide pyruvyl transferase
BCV50_16580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BCV50_16585	COG1620	l-lactate permease
BCV50_16590	COG2186	Transcriptional regulator
BCV50_16595	COG1609	Transcriptional regulator
BCV50_16600	COG2182	Extracellular solute-binding protein
BCV50_16605	COG1175	transmembrane transport
BCV50_16610	COG3833	ABC-type maltose transport systems, permease component
BCV50_16615	COG1874	Beta-galactosidase
BCV50_16620	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BCV50_16625	COG2208	phosphoserine phosphatase activity
BCV50_16630	COG0596	Alpha beta hydrolase
BCV50_16635	COG1131	(ABC) transporter
BCV50_16640	COG0842	Transport permease protein
BCV50_16645	COG4585	Histidine kinase
BCV50_16650	COG2197	response regulator
BCV50_16655	COG0247	lactate metabolic process
BCV50_16660	COG1139	Iron-sulfur cluster binding protein
BCV50_16665	COG1556	Lactate utilization protein
BCV50_16670	COG3858	chitin binding
BCV50_16675	COG1113	amino acid transport
BCV50_16680	COG0697	spore germination
BCV50_16685	COG0583	DNA-binding transcription factor activity
BCV50_16690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV50_16695	COG1609	Transcriptional regulator
BCV50_16700	COG2814	Major facilitator Superfamily
BCV50_16705	COG2390	Transcriptional regulator
BCV50_16710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCV50_16720	COG0126	phosphoglycerate kinase activity
BCV50_16730	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BCV50_16740	COG0456	acetyltransferase
BCV50_16745	COG4640	response to antibiotic
BCV50_16750	COG3064	Membrane
BCV50_16760	COG1510	regulation of RNA biosynthetic process
BCV50_16765	COG1125	glycine betaine transport
BCV50_16765	COG0517	IMP dehydrogenase activity
BCV50_16770	COG1174	glycine betaine transport
BCV50_16775	COG1732	Glycine betaine
BCV50_16780	COG1174	glycine betaine transport
BCV50_16785	COG1510	regulation of RNA biosynthetic process
BCV50_16790	COG1125	glycine betaine transport
BCV50_16790	COG0517	IMP dehydrogenase activity
BCV50_16795	COG1174	glycine betaine transport
BCV50_16800	COG1732	Glycine betaine
BCV50_16805	COG1174	glycine betaine transport
BCV50_16810	COG0840	transmembrane signaling receptor activity
BCV50_16815	COG1733	regulation of RNA biosynthetic process
BCV50_16820	COG1396	sequence-specific DNA binding
BCV50_16825	COG1396	sequence-specific DNA binding
BCV50_16830	COG1476	TRANSCRIPTIONal
BCV50_16835	COG0596	Alpha beta hydrolase
BCV50_16840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCV50_16845	COG1647	Serine aminopeptidase, S33
BCV50_16850	COG0557	exoribonuclease II activity
BCV50_16855	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BCV50_16865	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_16870	COG1309	transcriptional regulator
BCV50_16875	COG2076	Multidrug Resistance protein
BCV50_16885	COG1289	transmembrane transporter activity
BCV50_16890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BCV50_16895	COG0673	inositol 2-dehydrogenase activity
BCV50_16900	COG1937	Protein conserved in bacteria
BCV50_16905	COG2608	mercury ion transmembrane transporter activity
BCV50_16910	COG2217	Heavy metal translocating P-type atpase
BCV50_16915	COG2217	Heavy metal translocating P-type atpase
BCV50_16920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV50_16925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BCV50_16930	COG2801	Transposase and inactivated derivatives
BCV50_16940	COG2860	membrane
BCV50_16945	COG3973	AAA domain
BCV50_16950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCV50_16955	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCV50_16960	COG0025	NhaP-type Na H and K H
BCV50_16970	COG0656	L-ascorbic acid biosynthetic process
BCV50_16975	COG4149	molybdate abc transporter
BCV50_16980	COG0725	ABC transporter, periplasmic molybdate-binding protein
BCV50_16985	COG1910	domain protein
BCV50_16990	COG1368	sulfuric ester hydrolase activity
BCV50_16995	COG1988	membrane-bound metal-dependent
BCV50_17005	COG0531	amino acid
BCV50_17010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCV50_17015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV50_17020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV50_17025	COG1120	ATPase activity
BCV50_17030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV50_17035	COG1136	(ABC) transporter
BCV50_17040	COG0577	efflux transmembrane transporter activity
BCV50_17050	COG2140	Oxalate decarboxylase
BCV50_17060	COG1191	sigma factor activity
BCV50_17070	COG0745	RESPONSE REGULATOR receiver
BCV50_17075	COG2205	protein histidine kinase activity
BCV50_17080	COG3386	PFAM SMP-30 Gluconolaconase
BCV50_17085	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_17090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCV50_17095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV50_17100	COG1120	ATPase activity
BCV50_17105	COG2096	Adenosyltransferase
BCV50_17110	COG2814	Major facilitator Superfamily
BCV50_17115	COG4758	membrane
BCV50_17120	COG1842	Phage shock protein A
BCV50_17125	COG3595	metallopeptidase activity
BCV50_17130	COG4758	membrane
BCV50_17135	COG4585	Histidine kinase
BCV50_17140	COG2197	response regulator
BCV50_17150	COG0814	amino acid
BCV50_17155	COG0697	spore germination
BCV50_17165	COG0114	fumarate hydratase activity
BCV50_17170	COG1309	transcriptional regulator
BCV50_17180	COG2770	Histidine kinase
BCV50_17180	COG2205	protein histidine kinase activity
BCV50_17185	COG0745	RESPONSE REGULATOR receiver
BCV50_17190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV50_17195	COG0783	Belongs to the Dps family
BCV50_17200	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_17215	COG1120	ATPase activity
BCV50_17225	COG0583	DNA-binding transcription factor activity
BCV50_17230	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_17235	COG1942	4-Oxalocrotonate Tautomerase
BCV50_17240	COG0477	Major facilitator Superfamily
BCV50_17245	COG1846	Transcriptional regulator
BCV50_17250	COG5577	PFAM Coat F domain
BCV50_17260	COG0506	proline dehydrogenase activity
BCV50_17270	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCV50_17270	COG1024	Enoyl-CoA hydratase
BCV50_17275	COG0183	Belongs to the thiolase family
BCV50_17280	COG1960	acyl-CoA dehydrogenase activity
BCV50_17285	COG1393	Belongs to the ArsC family
BCV50_17290	COG0509	glycine decarboxylation via glycine cleavage system
BCV50_17300	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BCV50_17305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV50_17315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCV50_17320	COG2011	ABC-type metal ion transport system permease component
BCV50_17325	COG1464	Belongs to the NlpA lipoprotein family
BCV50_17330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV50_17340	COG0396	ATPase activity
BCV50_17345	COG0719	Fe-S assembly protein
BCV50_17350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCV50_17355	COG0822	iron-sulfur transferase activity
BCV50_17360	COG0719	Fe-S assembly protein
BCV50_17365	COG0640	Transcriptional regulator
BCV50_17370	COG0346	lactoylglutathione lyase activity
BCV50_17385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV50_17390	COG0322	excinuclease ABC activity
BCV50_17395	COG2222	sugar isomerase
BCV50_17400	COG1653	transport
BCV50_17405	COG1175	transmembrane transport
BCV50_17410	COG0395	ABC-type sugar transport system, permease component
BCV50_17415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV50_17420	COG2188	Transcriptional regulator
BCV50_17425	COG3842	ATPase activity
BCV50_17430	COG2356	endonuclease I
BCV50_17435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCV50_17440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV50_17445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BCV50_17450	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BCV50_17455	COG2068	MobA-Related Protein
BCV50_17460	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BCV50_17465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BCV50_17470	COG2080	2 iron, 2 sulfur cluster binding
BCV50_17485	COG2351	hydroxyisourate hydrolase activity
BCV50_17490	COG3195	allantoin biosynthetic process
BCV50_17490	COG3648	Uricase
BCV50_17495	COG2233	PERMEase
BCV50_17500	COG2233	PERMEase
BCV50_17505	COG2508	Transcriptional regulator
BCV50_17510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCV50_17515	COG1819	glycosyl
BCV50_17525	COG1801	Protein of unknown function DUF72
BCV50_17530	COG0730	response to heat
BCV50_17535	COG0737	Belongs to the 5'-nucleotidase family
BCV50_17540	COG3377	Domain of unknown function (DUF1805)
BCV50_17550	COG0739	heme binding
BCV50_17555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BCV50_17565	COG4470	Protein conserved in bacteria
BCV50_17570	COG2445	Protein of unknown function DUF86
BCV50_17575	COG0647	UMP catabolic process
BCV50_17580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCV50_17585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCV50_17590	COG0460	homoserine dehydrogenase
BCV50_17595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BCV50_17600	COG0083	homoserine kinase activity
BCV50_17605	COG0823	Involved in the tonB-independent uptake of proteins
BCV50_17605	COG1506	peptidase
BCV50_17605	COG4946	Tricorn protease homolog
BCV50_17610	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCV50_17615	COG4837	Protein of unknown function (DUF1462)
BCV50_17620	COG1252	NADH dehydrogenase
BCV50_17625	COG4844	belongs to the
BCV50_17630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCV50_17635	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BCV50_17640	COG0316	Belongs to the HesB IscA family
BCV50_17650	COG0456	acetyltransferase
BCV50_17655	COG2808	Putative FMN-binding domain
BCV50_17660	COG0516	GMP reductase activity
BCV50_17670	COG0492	ferredoxin-NADP+ reductase activity
BCV50_17675	COG1252	NADH dehydrogenase
BCV50_17690	COG3584	3D domain protein
BCV50_17695	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BCV50_17700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCV50_17705	COG2056	Na+-H+ antiporter family
BCV50_17710	COG1268	BioY protein
BCV50_17715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BCV50_17720	COG2819	hydrolase of the alpha beta superfamily
BCV50_17725	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_17730	COG1169	isochorismate synthase
BCV50_17735	COG1021	2,3-dihydroxybenzoate-AMP ligase
BCV50_17740	COG1535	isochorismatase
BCV50_17740	COG3433	isochorismatase activity
BCV50_17745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV50_17750	COG3251	PFAM MbtH domain protein
BCV50_17755	COG5634	Uncharacterized conserved protein (DUF2278)
BCV50_17760	COG0686	Belongs to the AlaDH PNT family
BCV50_17765	COG2508	Transcriptional regulator
BCV50_17765	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BCV50_17770	COG4842	Belongs to the WXG100 family
BCV50_17775	COG5417	Belongs to the EsaB family
BCV50_17780	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCV50_17785	COG0433	COG0433 Predicted ATPase
BCV50_17785	COG1674	ftsk spoiiie
BCV50_17790	COG1511	domain protein
BCV50_17800	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_17805	COG1418	mRNA catabolic process
BCV50_17820	COG0628	permease
BCV50_17835	COG5506	Protein of unknown function (DUF1694)
BCV50_17840	COG1335	isochorismatase
BCV50_17845	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BCV50_17850	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BCV50_17865	COG0142	geranyltranstransferase activity
BCV50_17880	COG2197	response regulator
BCV50_17885	COG2050	protein possibly involved in aromatic compounds catabolism
BCV50_17890	COG1320	monovalent cation:proton antiporter activity
BCV50_17895	COG2212	antiporter activity
BCV50_17900	COG1863	multisubunit Na H antiporter MnhE subunit
BCV50_17905	COG0651	ATP synthesis coupled electron transport
BCV50_17910	COG1006	Multisubunit Na H antiporter MnhC subunit
BCV50_17915	COG2111	Na H antiporter
BCV50_17920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCV50_17920	COG2111	Na H antiporter
BCV50_17930	COG3493	citrate carrier protein
BCV50_17955	COG4565	transcriptional regulatory protein
BCV50_17960	COG3290	protein histidine kinase activity
BCV50_17970	COG3011	Protein conserved in bacteria
BCV50_17975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV50_17980	COG2814	Major facilitator Superfamily
BCV50_17990	COG5018	Exonuclease
BCV50_18000	COG2205	protein histidine kinase activity
BCV50_18005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BCV50_18015	COG2267	carboxylic ester hydrolase activity
BCV50_18020	COG1522	sequence-specific DNA binding
BCV50_18025	COG0436	Aminotransferase
BCV50_18030	COG1098	S1 RNA binding domain
BCV50_18035	COG2155	Conserved Protein
BCV50_18040	COG1979	alcohol dehydrogenase
BCV50_18045	COG1979	alcohol dehydrogenase
BCV50_18050	COG0166	Belongs to the GPI family
BCV50_18065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCV50_18080	COG2738	Putative neutral zinc metallopeptidase
BCV50_18085	COG1253	flavin adenine dinucleotide binding
BCV50_18090	COG0366	Alpha amylase catalytic
BCV50_18095	COG0432	Pfam Uncharacterised protein family UPF0047
BCV50_18100	COG2070	2-Nitropropane dioxygenase
BCV50_18115	COG0840	transmembrane signaling receptor activity
BCV50_18120	COG0840	transmembrane signaling receptor activity
BCV50_18125	COG0840	transmembrane signaling receptor activity
BCV50_18130	COG0840	transmembrane signaling receptor activity
BCV50_18135	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_18135	COG3347	Dehydrogenase
BCV50_18140	COG1349	DNA-binding transcription factor activity
BCV50_18145	COG1070	Carbohydrate kinase
BCV50_18150	COG3254	rhamnose metabolic process
BCV50_18155	COG4806	L-rhamnose isomerase
BCV50_18160	COG0673	inositol 2-dehydrogenase activity
BCV50_18165	COG0628	permease
BCV50_18170	COG1968	undecaprenyl-diphosphatase activity
BCV50_18180	COG5553	Cysteine dioxygenase type I
BCV50_18185	COG0477	Major facilitator Superfamily
BCV50_18190	COG1705	Flagellar rod assembly protein muramidase FlgJ
BCV50_18195	COG4682	membrane
BCV50_18200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCV50_18205	COG0569	domain protein
BCV50_18215	COG1510	regulation of RNA biosynthetic process
BCV50_18225	COG1454	alcohol dehydrogenase
BCV50_18235	COG2318	DinB family
BCV50_18240	COG1585	Membrane protein implicated in regulation of membrane protease activity
BCV50_18245	COG2268	Band 7 protein
BCV50_18250	COG1247	-acetyltransferase
BCV50_18255	COG3859	Proton-coupled thiamine transporter YuaJ
BCV50_18385	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BCV50_18390	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BCV50_18395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BCV50_18400	COG0297	glycogen (starch) synthase activity
BCV50_18405	COG0058	SHG alpha-glucan phosphorylase activity
BCV50_18410	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BCV50_18415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCV50_18420	COG1169	isochorismate synthase
BCV50_18425	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BCV50_18430	COG0596	Alpha beta hydrolase
BCV50_18435	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BCV50_18440	COG0318	PFAM AMP-dependent synthetase and ligase
BCV50_18445	COG4948	Mandelate Racemase Muconate Lactonizing
BCV50_18450	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCV50_18455	COG1121	(ABC) transporter
BCV50_18460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCV50_18460	COG1321	iron dependent repressor
BCV50_18465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCV50_18475	COG1294	oxidase, subunit
BCV50_18480	COG1271	oxidase subunit
BCV50_18485	COG0254	rRNA binding
BCV50_18490	COG0288	reversible hydration of carbon dioxide
BCV50_18495	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BCV50_18500	COG1854	S-ribosylhomocysteine lyase activity
BCV50_18515	COG0783	Belongs to the Dps family
BCV50_18520	COG4824	toxin secretion phage lysis holin
BCV50_18525	COG0494	nUDIX hydrolase
BCV50_18530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCV50_18535	COG1116	anion transmembrane transporter activity
BCV50_18540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCV50_18545	COG1506	peptidase
BCV50_18555	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BCV50_18560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BCV50_18565	COG0367	asparagine synthase
BCV50_18570	COG1113	amino acid transport
BCV50_18575	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV50_18580	COG2267	carboxylic ester hydrolase activity
BCV50_18590	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BCV50_18595	COG1242	4 iron, 4 sulfur cluster binding
BCV50_18610	COG1725	Transcriptional regulator
BCV50_18615	COG1131	(ABC) transporter
BCV50_18630	COG1136	(ABC) transporter
BCV50_18635	COG0577	efflux transmembrane transporter activity
BCV50_18660	COG0745	RESPONSE REGULATOR receiver
BCV50_18665	COG2205	protein histidine kinase activity
BCV50_18670	COG1136	(ABC) transporter
BCV50_18675	COG0577	efflux transmembrane transporter activity
BCV50_18680	COG2433	Pfam Transposase IS66
BCV50_18685	COG2814	Major facilitator Superfamily
BCV50_18690	COG1366	Belongs to the anti-sigma-factor antagonist family
BCV50_18690	COG2202	Pas domain
BCV50_18700	COG0495	leucyl-tRNA aminoacylation
BCV50_18705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV50_18710	COG1486	melibiose metabolic process
BCV50_18735	COG1073	alpha beta
BCV50_18745	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BCV50_18750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCV50_18755	COG0156	8-amino-7-oxononanoate synthase activity
BCV50_18765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BCV50_18770	COG2124	cytochrome p450
BCV50_18775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV50_18780	COG0395	ABC-type sugar transport system, permease component
BCV50_18785	COG1653	transport
BCV50_18790	COG2207	Transcriptional regulator
BCV50_18795	COG4209	transmembrane transport
BCV50_18800	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BCV50_18805	COG1653	transport
BCV50_18810	COG0673	inositol 2-dehydrogenase activity
BCV50_18815	COG5578	integral membrane protein
BCV50_18825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCV50_18830	COG2081	HI0933 family
BCV50_18835	COG2244	polysaccharide biosynthetic process
BCV50_18840	COG1187	pseudouridine synthase activity
BCV50_18845	COG1349	DNA-binding transcription factor activity
BCV50_18850	COG1131	(ABC) transporter
BCV50_18855	COG4473	ABC transporter
BCV50_18860	COG2252	PERMEase
BCV50_18865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV50_18870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCV50_18875	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BCV50_18885	COG1597	lipid kinase activity
BCV50_18890	COG1523	belongs to the glycosyl hydrolase 13 family
BCV50_18895	COG0510	thiamine kinase activity
BCV50_18905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BCV50_18910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV50_18915	COG0281	malic enzyme
BCV50_18920	COG5584	Small secreted protein
BCV50_18925	COG1363	Peptidase, m42
BCV50_18935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV50_18940	COG4848	Belongs to the UPF0354 family
BCV50_18945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV50_18950	COG1674	ftsk spoiiie
BCV50_18955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCV50_18960	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BCV50_18965	COG4980	gas vesicle protein
BCV50_18970	COG3118	belongs to the thioredoxin family
BCV50_18975	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BCV50_18975	COG1605	Chorismate mutase
BCV50_18980	COG1609	Transcriptional regulator
BCV50_18985	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCV50_18990	COG1360	Flagellar Motor Protein
BCV50_18995	COG0123	including yeast histone deacetylase and acetoin utilization protein
BCV50_19000	COG0517	IMP dehydrogenase activity
BCV50_19005	COG0454	-acetyltransferase
BCV50_19010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCV50_19015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCV50_19025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCV50_19030	COG2203	Gaf domain
BCV50_19030	COG2199	diguanylate cyclase activity
BCV50_19035	COG1956	GAF domain-containing protein
BCV50_19040	COG1309	transcriptional regulator
BCV50_19045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCV50_19050	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BCV50_19055	COG1114	Component of the transport system for branched-chain amino acids
BCV50_19060	COG1104	cysteine desulfurase activity
BCV50_19065	COG0301	tRNA thio-modification
BCV50_19075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCV50_19080	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BCV50_19085	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BCV50_19090	COG0616	signal peptide processing
BCV50_19095	COG1714	RDD family
BCV50_19105	COG3874	Sporulation protein YtfJ
BCV50_19110	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BCV50_19115	COG0827	DNA restriction-modification system
BCV50_19120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCV50_19125	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCV50_19130	COG0137	argininosuccinate synthase activity
BCV50_19135	COG0165	Argininosuccinate lyase
BCV50_19145	COG1028	Short-chain dehydrogenase reductase Sdr
BCV50_19150	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BCV50_19155	COG0583	DNA-binding transcription factor activity
BCV50_19160	COG0454	-acetyltransferase
BCV50_19165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV50_19170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV50_19175	COG0765	amino acid transport
BCV50_19180	COG0765	amino acid transport
BCV50_19185	COG1126	abc transporter atp-binding protein
BCV50_19190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV50_19195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BCV50_19200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV50_19205	COG0196	riboflavin kinase activity
BCV50_19210	COG1473	amidohydrolase
BCV50_19215	COG0730	response to heat
BCV50_19225	COG4109	DRTGG domain
BCV50_19235	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BCV50_19255	COG0587	DNA-directed DNA polymerase activity
BCV50_19260	COG0281	malic enzyme
BCV50_19265	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BCV50_19270	COG0825	malonyl-CoA metabolic process
BCV50_19275	COG0205	6-phosphofructokinase activity
BCV50_19280	COG0469	pyruvate kinase activity
BCV50_19285	COG3030	protein affecting phage T7 exclusion by the F plasmid
BCV50_19290	COG0628	permease
BCV50_19295	COG2707	UPF0756 membrane protein
BCV50_19300	COG0372	Belongs to the citrate synthase family
BCV50_19305	COG0538	isocitrate dehydrogenase activity
BCV50_19310	COG0039	L-malate dehydrogenase activity
BCV50_19315	COG0745	RESPONSE REGULATOR receiver
BCV50_19320	COG5002	protein histidine kinase activity
BCV50_19325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCV50_19325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCV50_19330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCV50_19345	COG0237	dephospho-CoA kinase activity
BCV50_19350	COG0656	L-ascorbic acid biosynthetic process
BCV50_19355	COG2814	Major facilitator Superfamily
BCV50_19360	COG1733	regulation of RNA biosynthetic process
BCV50_19365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCV50_19370	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BCV50_19375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BCV50_19380	COG3611	Membrane attachment protein
BCV50_19385	COG1484	DNA-dependent DNA replication
BCV50_19390	COG0398	Pfam SNARE associated Golgi protein
BCV50_19400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCV50_19410	COG3275	phosphorelay sensor kinase activity
BCV50_19415	COG3279	Response regulator of the LytR AlgR family
BCV50_19420	COG1380	Effector of murein hydrolase LrgA
BCV50_19425	COG1346	cytolysis
BCV50_19440	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCV50_19445	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BCV50_19450	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BCV50_19455	COG3326	Membrane
BCV50_19465	COG1363	Peptidase, m42
BCV50_19470	COG3507	Belongs to the glycosyl hydrolase 43 family
BCV50_19475	COG2160	L-arabinose isomerase activity
BCV50_19480	COG1069	ribulokinase activity
BCV50_19485	COG0235	Class ii aldolase
BCV50_19490	COG0647	UMP catabolic process
BCV50_19495	COG0371	Dehydrogenase
BCV50_19500	COG1653	transport
BCV50_19505	COG1175	transmembrane transport
BCV50_19510	COG0395	ABC-type sugar transport system, permease component
BCV50_19515	COG3534	alpha-L-arabinofuranosidase
BCV50_19520	COG1695	Transcriptional regulator
BCV50_19535	COG1966	Carbon starvation protein
BCV50_19540	COG0346	lactoylglutathione lyase activity
BCV50_19545	COG0247	lactate metabolic process
BCV50_19550	COG0277	FAD linked oxidase domain protein
BCV50_19555	COG3835	regulator
BCV50_19565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV50_19575	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCV50_19580	COG0072	phenylalanine-tRNA ligase activity
BCV50_19580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV50_19585	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BCV50_19590	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BCV50_19595	COG1286	toxin biosynthetic process
BCV50_19600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCV50_19600	COG1796	DNA polymerase
BCV50_19605	COG1193	negative regulation of DNA recombination
BCV50_19610	COG3766	membrane
BCV50_19615	COG0318	PFAM AMP-dependent synthetase and ligase
BCV50_19620	COG1309	transcriptional regulator
BCV50_19625	COG1024	Enoyl-CoA hydratase
BCV50_19630	COG2086	electron transfer activity
BCV50_19635	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BCV50_19640	COG3534	alpha-L-arabinofuranosidase
BCV50_19645	COG3118	belongs to the thioredoxin family
BCV50_19650	COG0322	excinuclease ABC activity
BCV50_19655	COG0527	aspartate kinase activity
BCV50_19660	COG1719	4-vinyl reductase, 4VR
BCV50_19670	COG2009	succinate dehydrogenase
BCV50_19675	COG1053	succinate dehydrogenase
BCV50_19680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCV50_19685	COG0824	Thioesterase
BCV50_19690	COG2197	response regulator
BCV50_19695	COG1846	Transcriptional regulator
BCV50_19700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BCV50_19705	COG5401	PFAM Sporulation and spore germination
BCV50_19710	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BCV50_19715	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BCV50_19720	COG0622	Phosphoesterase
BCV50_19730	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BCV50_19735	COG0454	-acetyltransferase
BCV50_19745	COG0028	Belongs to the TPP enzyme family
BCV50_19750	COG0440	acetolactate synthase activity
BCV50_19755	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCV50_19760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCV50_19765	COG0473	3-isopropylmalate dehydrogenase activity
BCV50_19770	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCV50_19775	COG0066	3-isopropylmalate dehydratase activity
BCV50_19780	COG1477	protein flavinylation
BCV50_19780	COG0457	Tetratricopeptide repeat
BCV50_19785	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCV50_19790	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BCV50_19795	COG0470	DNA polymerase III
BCV50_19795	COG1067	ATP-dependent peptidase activity
BCV50_19800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BCV50_19805	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BCV50_19815	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BCV50_19820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCV50_19825	COG0181	hydroxymethylbilane synthase activity
BCV50_19830	COG1587	Uroporphyrinogen-III synthase
BCV50_19835	COG0113	porphobilinogen synthase activity
BCV50_19840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCV50_19845	COG1388	LysM domain
BCV50_19850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCV50_19860	COG0525	valine-tRNA ligase activity
BCV50_19865	COG0285	dihydrofolate synthase activity
BCV50_19870	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BCV50_19880	COG0424	maF-like protein
BCV50_19885	COG2003	Belongs to the UPF0758 family
BCV50_19890	COG1077	Cell shape determining protein MreB Mrl
BCV50_19895	COG1792	Involved in formation and maintenance of cell shape
BCV50_19900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BCV50_19905	COG0850	regulation of cytokinetic process
BCV50_19910	COG2894	cell division
BCV50_19915	COG0739	heme binding
BCV50_19920	COG1994	Peptidase M50
BCV50_19925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BCV50_19930	COG2868	ribosomal protein
BCV50_19935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BCV50_19945	COG3290	protein histidine kinase activity
BCV50_19950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BCV50_19955	COG4492	Belongs to the UPF0735 family
BCV50_19960	COG0077	Prephenate dehydratase
BCV50_19965	COG1827	regulation of RNA biosynthetic process
BCV50_19970	COG1104	cysteine desulfurase activity
BCV50_19975	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCV50_19980	COG0157	Belongs to the NadC ModD family
BCV50_19985	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BCV50_19990	COG1388	LysM domain
BCV50_20000	COG0217	transcriptional regulatory protein
BCV50_20005	COG1115	amino acid carrier protein
BCV50_20025	COG2112	serine threonine protein kinase
BCV50_20030	COG0673	inositol 2-dehydrogenase activity
BCV50_20035	COG2814	Major facilitator Superfamily
BCV50_20045	COG0632	four-way junction helicase activity
BCV50_20050	COG2255	four-way junction helicase activity
BCV50_20060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BCV50_20065	COG0343	queuine tRNA-ribosyltransferase activity
BCV50_20070	COG1862	Preprotein translocase
BCV50_20080	COG2323	membrane
BCV50_20085	COG2244	polysaccharide biosynthetic process
BCV50_20095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCV50_20095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCV50_20100	COG0490	domain, Protein
BCV50_20105	COG5416	Lipopolysaccharide assembly protein A domain
BCV50_20110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCV50_20110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BCV50_20115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCV50_20120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV50_20125	COG1490	D-aminoacyl-tRNA deacylase activity
BCV50_20130	COG4991	sh3 domain protein
BCV50_20130	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV50_20130	COG3103	Sh3 type 3 domain protein
BCV50_20140	COG0124	histidyl-tRNA synthetase
BCV50_20145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BCV50_20155	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCV50_20160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCV50_20165	COG1959	2 iron, 2 sulfur cluster binding
BCV50_20170	COG1104	cysteine desulfurase activity
BCV50_20175	COG0482	sulfurtransferase activity
BCV50_20180	COG0457	Tetratricopeptide repeat
BCV50_20185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV50_20190	COG3881	PFAM PRC-barrel domain
BCV50_20205	COG0765	amino acid transport
BCV50_20210	COG0765	amino acid transport
BCV50_20215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV50_20220	COG1126	abc transporter atp-binding protein
BCV50_20225	COG0628	permease
BCV50_20230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCV50_20235	COG4472	Bacterial protein of unknown function (DUF965)
BCV50_20240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BCV50_20245	COG3906	Belongs to the UPF0473 family
BCV50_20250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCV50_20270	COG0572	uridine kinase
BCV50_20275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV50_20280	COG0768	penicillin binding
BCV50_20295	COG2226	methyltransferase
BCV50_20300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCV50_20305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCV50_20310	COG0626	cystathionine gamma-synthase activity
BCV50_20320	COG2427	Protein of unknown function (DUF1641)
BCV50_20325	COG3383	formate dehydrogenase (NAD+) activity
BCV50_20330	COG5609	conserved protein (DUF2294)
BCV50_20335	COG2116	formate transmembrane transporter activity
BCV50_20345	COG2226	methyltransferase
BCV50_20350	COG1309	transcriptional regulator
BCV50_20355	COG2124	cytochrome p450
BCV50_20355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCV50_20365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BCV50_20365	COG2755	lipolytic protein G-D-S-L family
BCV50_20375	COG1595	DNA-templated transcription, initiation
BCV50_20380	COG1378	Sugar-specific transcriptional regulator TrmB
BCV50_20385	COG1280	lysine exporter protein (LysE YggA)
BCV50_20390	COG1113	amino acid transport
BCV50_20400	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCV50_20400	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCV50_20405	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV50_20410	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV50_20415	COG3715	PTS system
BCV50_20420	COG3716	PTS system mannose fructose sorbose family IID component
BCV50_20425	COG1621	beta-fructofuranosidase activity
BCV50_20430	COG0693	protein deglycase activity
BCV50_20440	COG5577	PFAM Coat F domain
BCV50_20450	COG1063	alcohol dehydrogenase
BCV50_20455	COG5577	PFAM Coat F domain
BCV50_20465	COG4991	sh3 domain protein
BCV50_20470	COG4991	sh3 domain protein
BCV50_20475	COG0110	maltose O-acetyltransferase activity
BCV50_20480	COG0697	spore germination
BCV50_20485	COG0596	Alpha beta hydrolase
BCV50_20490	COG5566	PFAM Mor transcription activator
BCV50_20495	COG3409	Peptidoglycan-binding domain 1 protein
BCV50_20500	COG2828	Protein conserved in bacteria
BCV50_20505	COG0583	DNA-binding transcription factor activity
BCV50_20510	COG2851	Citrate transporter
BCV50_20520	COG3443	Belongs to the bacterial solute-binding protein 9 family
BCV50_20530	COG4608	Belongs to the ABC transporter superfamily
BCV50_20535	COG0444	Belongs to the ABC transporter superfamily
BCV50_20540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV50_20545	COG0601	transmembrane transport
BCV50_20550	COG0747	negative chemotaxis
BCV50_20555	COG0789	Transcriptional regulator
BCV50_20555	COG4978	Transcriptional regulator
BCV50_20590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV50_20595	COG0477	Major facilitator Superfamily
BCV50_20600	COG0456	acetyltransferase
BCV50_20605	COG2318	DinB family
BCV50_20610	COG1917	Cupin 2, conserved barrel domain protein
BCV50_20610	COG2207	Transcriptional regulator
BCV50_20615	COG0697	spore germination
BCV50_20685	COG4824	toxin secretion phage lysis holin
BCV50_20690	COG3409	Peptidoglycan-binding domain 1 protein
BCV50_20690	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCV50_20715	COG0457	Tetratricopeptide repeat
BCV50_20720	COG0583	DNA-binding transcription factor activity
BCV50_20725	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCV50_20735	COG2807	transmembrane transport
BCV50_20740	COG2814	Major facilitator Superfamily
BCV50_20750	COG1819	glycosyl
BCV50_20755	COG0583	DNA-binding transcription factor activity
BCV50_20760	COG0114	fumarate hydratase activity
BCV50_20765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCV50_20775	COG3209	COG3209 Rhs family protein
BCV50_20785	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BCV50_20790	COG0398	Pfam SNARE associated Golgi protein
BCV50_20795	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCV50_20795	COG3409	Peptidoglycan-binding domain 1 protein
BCV50_20800	COG2755	lipolytic protein G-D-S-L family
BCV50_20815	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BCV50_20820	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BCV50_20825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCV50_20830	COG1534	Rna-binding protein
BCV50_20835	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCV50_20840	COG1713	HD superfamily hydrolase involved in NAD metabolism
BCV50_20845	COG0799	negative regulation of ribosome biogenesis
BCV50_20850	COG2226	methyltransferase
BCV50_20855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCV50_20860	COG1596	polysaccharide export
BCV50_20860	COG1555	photosystem II stabilization
BCV50_20865	COG2131	deaminase
BCV50_20870	COG2333	competence protein COMEC
BCV50_20870	COG0658	competence protein
BCV50_20880	COG1466	dna polymerase III delta subunit
BCV50_20885	COG0268	Binds directly to 16S ribosomal RNA
BCV50_20890	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BCV50_20895	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV50_20905	COG0481	GTPase activity
BCV50_20910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCV50_20915	COG1420	regulation of RNA biosynthetic process
BCV50_20920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCV50_20935	COG2264	protein methyltransferase activity
BCV50_20940	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCV50_20945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCV50_20950	COG1283	sodium-dependent phosphate transmembrane transporter activity
BCV50_20955	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BCV50_20960	COG1610	YqeY-like protein
BCV50_20965	COG1030	water channel activity
BCV50_20970	COG4864	UPF0365 protein
BCV50_20985	COG0561	phosphatase activity
BCV50_20990	COG1702	phosphate starvation-inducible protein PhoH
BCV50_21000	COG1480	7TM receptor with intracellular HD hydrolase
BCV50_21005	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BCV50_21010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCV50_21015	COG0295	cytidine deaminase activity
BCV50_21020	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCV50_21030	COG1381	Involved in DNA repair and RecF pathway recombination
BCV50_21035	COG0752	glycyl-tRNA synthetase alpha subunit
BCV50_21040	COG0751	glycine-tRNA ligase activity
BCV50_21045	COG0517	IMP dehydrogenase activity
BCV50_21050	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BCV50_21055	COG1671	Belongs to the UPF0178 family
BCV50_21060	COG0358	DNA primase activity
BCV50_21065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCV50_21070	COG2010	Cytochrome c
BCV50_21075	COG2384	SAM-dependent methyltransferase
BCV50_21080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BCV50_21085	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BCV50_21095	COG0513	Belongs to the DEAD box helicase family
BCV50_21100	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BCV50_21110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCV50_21115	COG0735	belongs to the Fur family
BCV50_21120	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BCV50_21125	COG4709	membrane
BCV50_21130	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BCV50_21135	COG1388	LysM domain
BCV50_21140	COG5521	maltodextrose utilization protein MalA
BCV50_21145	COG2839	Protein conserved in bacteria
BCV50_21150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCV50_21155	COG0477	Major facilitator Superfamily
BCV50_21165	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCV50_21170	COG0573	inorganic phosphate transmembrane transporter activity
BCV50_21175	COG0581	inorganic phosphate transmembrane transporter activity
BCV50_21180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCV50_21185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCV50_21190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCV50_21205	COG0438	transferase activity, transferring glycosyl groups
BCV50_21210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCV50_21215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCV50_21225	COG0705	Rhomboid family
BCV50_21225	COG0457	Tetratricopeptide repeat
BCV50_21230	COG4483	Protein conserved in bacteria
BCV50_21235	COG1940	carbohydrate kinase activity
BCV50_21240	COG1368	sulfuric ester hydrolase activity
BCV50_21245	COG2866	Carboxypeptidase
BCV50_21255	COG0011	TIGRFAM Protein of
BCV50_21265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV50_21275	COG1393	Belongs to the ArsC family
BCV50_21285	COG1366	Belongs to the anti-sigma-factor antagonist family
BCV50_21290	COG1253	flavin adenine dinucleotide binding
BCV50_21295	COG0598	Magnesium transport protein CorA
BCV50_21300	COG0517	IMP dehydrogenase activity
BCV50_21305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCV50_21310	COG1459	type II secretion system
BCV50_21315	COG4537	Required for transformation and DNA binding
BCV50_21320	COG4970	Tfp pilus assembly protein FimT
BCV50_21330	COG4940	Competence protein ComGF
BCV50_21355	COG0681	Belongs to the peptidase S26 family
BCV50_21365	COG1396	sequence-specific DNA binding
BCV50_21380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCV50_21385	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCV50_21390	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCV50_21395	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCV50_21400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV50_21405	COG0095	Lipoate-protein ligase
BCV50_21410	COG1321	iron dependent repressor
BCV50_21415	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCV50_21425	COG3872	metal-dependent enzyme
BCV50_21435	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCV50_21440	COG0006	proline dipeptidase activity
BCV50_21445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCV50_21455	COG3854	ATPases associated with a variety of cellular activities
BCV50_21495	COG0511	ligase activity, forming carbon-carbon bonds
BCV50_21500	COG0439	Biotin carboxylase
BCV50_21505	COG1302	Protein conserved in bacteria
BCV50_21510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCV50_21515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BCV50_21520	COG1570	exodeoxyribonuclease VII activity
BCV50_21525	COG1722	exodeoxyribonuclease VII activity
BCV50_21530	COG0142	geranyltranstransferase activity
BCV50_21535	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCV50_21540	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BCV50_21545	COG1438	arginine binding
BCV50_21550	COG0497	DNA recombination
BCV50_21555	COG0750	zinc metalloprotease