locus-tag class description FIU26_00005 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FIU26_00015 ENOG4105CAQ asparagine synthetase FIU26_00030 ENOG4105UQX Mate efflux family protein FIU26_00035 ENOG4106HBX Transcriptional Regulator AraC Family FIU26_00040 ENOG4105ETE Transcriptional regulator (LacI family FIU26_00045 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FIU26_00050 ENOG4105SF0 DinB family FIU26_00055 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FIU26_00060 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FIU26_00065 ENOG4105MYW Pentapeptide repeat protein FIU26_00070 ENOG4107S9D Alpha beta hydrolase FIU26_00075 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) FIU26_00080 ENOG4107RIQ Sulfate adenylate transferase FIU26_00085 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) FIU26_00090 ENOG4108N5B 2-phosphosulfolactate phosphatase FIU26_00095 ENOG41061P3 phosphosulfolactate synthase FIU26_00105 ENOG4105DIA mandelate racemase muconate lactonizing FIU26_00110 ENOG4107RCC Major Facilitator Superfamily FIU26_00115 ENOG4108SZE gCN5-related N-acetyltransferase FIU26_00120 ENOG4105MA6 gCN5-related N-acetyltransferase FIU26_00130 ENOG4108VPT UPF0234 protein FIU26_00135 ENOG4105QNR S1 RNA binding domain protein FIU26_00140 ENOG410751J FIU26_00145 ENOG4105EPR degv family FIU26_00150 ENOG4107AYK membrAne FIU26_00160 ENOG41073B9 FIU26_00165 ENOG4108KP7 hydrolase FIU26_00170 ENOG4108MXZ Esterase FIU26_00175 ENOG4105VG1 fes assembly suf system protein FIU26_00185 ENOG4105IQ5 FAD linked oxidase domain protein FIU26_00195 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FIU26_00210 ENOG4105C8Y Acetylornithine aminotransferase FIU26_00215 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FIU26_00225 ENOG4105DBV ornithine carbamoyltransferase FIU26_00250 ENOG4107RMD Basic membrane lipoprotein FIU26_00265 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FIU26_00270 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FIU26_00280 ENOG4105C3U ABC transporter FIU26_00285 ENOG4108JQ7 (ABC) transporter FIU26_00300 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FIU26_00310 ENOG4105C31 Tryptophanyl-tRNA synthetase FIU26_00320 ENOG4108J59 Extracellular solute-binding protein, family 5 FIU26_00325 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FIU26_00330 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FIU26_00340 ENOG4108JQ7 (ABC) transporter FIU26_00355 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) FIU26_00360 ENOG4108ZCF integral membrane protein FIU26_00370 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis FIU26_00385 ENOG4105DPN Oligoendopeptidase f FIU26_00400 ENOG4105T58 Dithiol-disulfide isomerase FIU26_00405 ENOG4108Z18 K06886 hemoglobin FIU26_00410 ENOG4105E4C Lytic transglycosylase catalytic FIU26_00415 ENOG4105MIX Adenylate cyclase FIU26_00430 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FIU26_00435 ENOG4105EMS pseudouridine synthase FIU26_00450 ENOG4105ETU transcriptional activator (TenA FIU26_00455 ENOG4108VEU Thiamine monophosphate synthase FIU26_00470 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) FIU26_00475 ENOG4105D06 uba thif-type nad fad binding protein FIU26_00480 ENOG4105DWF phosphomethylpyrimidine kinase FIU26_00485 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FIU26_00490 ENOG4107A88 FIU26_00540 ENOG4105ENA helicase FIU26_00555 ENOG4108ZMI UPF0477 protein FIU26_00565 ENOG4105C28 cystathionine FIU26_00570 ENOG4105C28 cystathionine FIU26_00580 ENOG4105JHY Membrane FIU26_00640 ENOG4105DM4 PTS System FIU26_00645 ENOG4105DG6 mannose-6-phosphate isomerase FIU26_00665 ENOG4108Z66 YbaK ebsC protein FIU26_00680 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) FIU26_00690 ENOG4108ZJ4 polysaccharide deacetylase FIU26_00695 ENOG4107CUJ Protein of unknown function (DUF2690) FIU26_00720 ENOG4108IEG Formate dehydrogenase Alpha subunit FIU26_00745 ENOG4106A3M Cytochrome p-450 FIU26_00750 ENOG41087PP glycosyltransferase MGT family FIU26_00760 ENOG4105EXQ uroporphyrinogen iii synthase hem4 FIU26_00765 ENOG4105C4B ABC transporter, permease FIU26_00770 ENOG4108IXI (ABC) transporter FIU26_00780 ENOG4105Q95 Cupin 2, conserved barrel domain protein FIU26_00795 ENOG4105D2H Uronic isomerase FIU26_00800 ENOG4105CT4 transporter FIU26_00805 ENOG4105DG4 malate L-lactate dehydrogenase FIU26_00810 ENOG4105CPQ Dehydrogenase FIU26_00815 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) FIU26_00820 ENOG4105DMW Dehydrogenase reductase FIU26_00825 ENOG4108I5G Major Facilitator superfamily FIU26_00830 ENOG4107KJX Transcriptional regulator FIU26_00835 ENOG4107QZW Altronate oxidoreductase FIU26_00840 ENOG4105CTX dehydratase FIU26_00845 ENOG4107TSN permease FIU26_00855 ENOG4105JD4 ATPase yjob FIU26_00870 ENOG41068K0 YCII-related domain FIU26_00875 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase FIU26_00880 ENOG4105KWG Pfam:DUF1696 FIU26_00885 ENOG4105K7W phage-related replication protein FIU26_00890 ENOG4105WEF catalase FIU26_00895 ENOG410635T phage-like element pbsx protein FIU26_00940 ENOG4108TFU terminase (Small subunit) FIU26_00945 ENOG4105IG6 Phage terminase, large subunit FIU26_00950 ENOG4108MDF Phage Portal Protein FIU26_00975 ENOG41060SN FIU26_00990 ENOG4105PQS phage protein FIU26_00995 ENOG4105FR7 XkdM protein, phage-like element PBSX FIU26_01000 ENOG4105MTC XkdN-like protein FIU26_01010 ENOG4108FKH Transglycosylase SLT domain FIU26_01010 ENOG4108FKH Transglycosylase SLT domain FIU26_01010 ENOG4108FKH Transglycosylase SLT domain FIU26_01015 ENOG4108WZM domain protein FIU26_01020 ENOG4105X7F FIU26_01030 ENOG4105MFU Protein of unknown function (DUF2634) FIU26_01035 ENOG41066EA baseplate J family protein FIU26_01040 ENOG410906S phage-like element pbsx protein xkdt FIU26_01050 ENOG41068G1 FIU26_01080 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FIU26_01100 ENOG4105CJ3 phosphate transporter FIU26_01105 ENOG4107GRR phosphate transport regulator FIU26_01110 ENOG4107R7I amino acid FIU26_01125 ENOG4105EDW glycosyl transferase, family 39 FIU26_01130 ENOG4105CKK Glycosyl transferase, family 2 FIU26_01135 ENOG4105C0H protease FIU26_01145 ENOG4108ME1 Peptidase M55 D-aminopeptidase FIU26_01150 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FIU26_01155 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FIU26_01160 ENOG4105C3U ABC transporter FIU26_01170 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FIU26_01175 ENOG4105DTQ mandelate racemase muconate lactonizing FIU26_01180 ENOG4107SN7 NLP P60 protein FIU26_01185 ENOG4108JQ7 (ABC) transporter FIU26_01190 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FIU26_01195 ENOG4107TUM Amidinotransferase FIU26_01200 ENOG4108S4H thioesterase Superfamily protein FIU26_01205 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FIU26_01225 ENOG4108428 Inherit from COG: -acetyltransferase FIU26_01235 ENOG41080TC multidrug resistance protein FIU26_01240 ENOG4105CIY formyltetrahydrofolate deformylase FIU26_01245 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FIU26_01260 ENOG4105K56 Transcriptional regulator FIU26_01265 ENOG4108ZHJ Organic hydroperoxide resistance protein FIU26_01270 ENOG4107TVC Glycosyl transferase, family 2 FIU26_01275 ENOG4107Y2X deaminase FIU26_01285 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) FIU26_01290 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FIU26_01300 ENOG4108W7F transporter, permease FIU26_01305 ENOG4108JJB ABC transporter FIU26_01310 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein FIU26_01315 ENOG4108X43 YKOF domain protein FIU26_01320 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FIU26_01325 ENOG41062D9 Histidine kinase FIU26_01335 ENOG4106849 propeptide, pepSY amd peptidase M4 FIU26_01345 ENOG4105CJW magnesium transporter FIU26_01350 ENOG4105V75 Transcriptional regulator FIU26_01395 ENOG4105DQE DNA ligase FIU26_01400 ENOG4105FDF Could be involved in DNA repair (By similarity) FIU26_01405 ENOG4105BZU Histidine kinase FIU26_01410 ENOG4107T5V SNARE associated Golgi FIU26_01415 ENOG4107TS3 membrane protein, TerC FIU26_01420 ENOG4108WZW RNA polymerase sigma FIU26_01430 ENOG410681C small acid-soluble spore protein FIU26_01440 ENOG4105D0M Protease HtpX homolog FIU26_01460 ENOG4108TGC Acyltransferase FIU26_01465 ENOG4105BZU Histidine kinase FIU26_01470 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FIU26_01480 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) FIU26_01485 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) FIU26_01490 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FIU26_01500 ENOG4107T6J Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit FIU26_01505 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) FIU26_01510 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) FIU26_01515 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) FIU26_01535 ENOG4105BZU Histidine kinase FIU26_01545 ENOG41090MY MarR family Transcriptional regulator FIU26_01550 ENOG4105ER2 Ompa motb domain protein FIU26_01555 ENOG4105E14 MotA TolQ exbB proton channel FIU26_01565 ENOG4108K88 Membrane FIU26_01570 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) FIU26_01575 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase FIU26_01580 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FIU26_01585 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) FIU26_01610 ENOG4105F0V Cell wall hydrolase FIU26_01625 ENOG4105C59 p-type ATPase FIU26_01635 ENOG4105DC7 peptidase M24 FIU26_01645 ENOG4105CID antiterminator FIU26_01655 ENOG4105KRI phosphocarrier protein (HPr FIU26_01660 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FIU26_01670 ENOG4105F6S Spore photoproduct lyase FIU26_01680 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FIU26_01685 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FIU26_01690 ENOG4105K4I Scp-like extracellular FIU26_01700 ENOG4105BZU Histidine kinase FIU26_01705 ENOG4105CHM Aminotransferase FIU26_01715 ENOG4107R88 Chemotaxis protein (CheV) FIU26_01720 ENOG4105UIN FIU26_01730 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein FIU26_01740 ENOG4105K6S Short-chain dehydrogenase reductase Sdr FIU26_01745 ENOG4105EPM Diguanylate phosphodiesterase FIU26_01750 ENOG4107IN1 Protein of unknown function (DUF1797) FIU26_01755 ENOG4108XRC Protein of unknown function (DUF458) FIU26_01785 ENOG4105NQC Flavodoxin FIU26_01795 ENOG4105CH2 amidohydrolase FIU26_01805 ENOG4105D8X mechanosensitive ion channel FIU26_01810 ENOG4105D3R alkyl hydroperoxide reductase FIU26_01815 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FIU26_01830 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FIU26_01835 ENOG4105D06 uba thif-type nad fad binding protein FIU26_01840 ENOG4105CVM Molybdenum cofactor synthesis domain protein FIU26_01845 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein FIU26_01850 ENOG4108ZAF Molybdopterin FIU26_01855 ENOG41067WU Molybdopterin converting factor (Subunit 1) FIU26_01860 ENOG4105BZ1 (ABC) transporter FIU26_01865 ENOG4105BZ1 (ABC) transporter FIU26_01875 ENOG4107X8C Efflux transporter RND family MFP subunit FIU26_01880 ENOG4105C19 ABC transporter FIU26_01885 ENOG4107RBB ABC transporter, permease FIU26_01890 ENOG4105E98 transcriptional regulator DeoR family FIU26_01895 ENOG4105DE4 1-phosphofructokinase FIU26_01900 ENOG4105DM4 PTS System FIU26_01910 ENOG4105C3F Signal peptidase i FIU26_01920 ENOG4105C5H ABC transporter FIU26_01925 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FIU26_01950 ENOG4105BZU Histidine kinase FIU26_01960 ENOG4107ZYR domain protein FIU26_01970 ENOG4105CN5 Metallo-Beta-Lactamase FIU26_01980 ENOG4108X4Q Hydrolase FIU26_01985 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FIU26_02005 ENOG4105CPP Dehydrogenase, E1 component FIU26_02010 ENOG4105C7S Dehydrogenase FIU26_02015 ENOG4107QN2 dihydrolipoyl dehydrogenase FIU26_02035 ENOG4105CXN decarboxylase FIU26_02040 ENOG4105WBI UPF0223 protein FIU26_02055 ENOG4105ECY inositol monophosphatase FIU26_02065 ENOG4105JQZ Methyltransferase FIU26_02105 ENOG4105CI3 gtp-binding protein typa FIU26_02110 ENOG4105QA2 FIU26_02125 ENOG4108IAB Phoh family FIU26_02135 ENOG4105CSV Glutaminase FIU26_02140 ENOG4105ZPI UPF0358 protein FIU26_02145 ENOG4105CNI cell division protein FtsW FIU26_02150 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FIU26_02160 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) FIU26_02170 ENOG4105BZ9 Cytochrome C oxidase, subunit I FIU26_02175 ENOG4105CCU oxidase (Subunit III) FIU26_02180 ENOG41064X9 cytochrome C oxidase subunit IV FIU26_02195 ENOG41080XQ Signal transduction protein with cbs domains FIU26_02200 ENOG4106UY4 Inherit from COG: Scp-like extracellular FIU26_02220 ENOG4105WUC UPF0298 protein FIU26_02225 ENOG4106H78 methyltransferase FIU26_02230 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) FIU26_02235 ENOG4105H20 Sporulation integral membrane protein YlbJ FIU26_02240 ENOG4105D78 K07001 NTE family protein FIU26_02245 ENOG41063PX domain protein FIU26_02250 ENOG4105CDE UPF0348 protein FIU26_02255 ENOG4105KNH Nucleic acid-binding protein FIU26_02260 ENOG41067VY 50S ribosomal protein L32 FIU26_02285 ENOG4108V6E Cell division protein mraZ FIU26_02290 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) FIU26_02300 ENOG4105CJN penicillin-binding protein FIU26_02305 ENOG4105CJN penicillin-binding protein FIU26_02310 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FIU26_02315 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) FIU26_02320 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FIU26_02325 ENOG4105CNI cell division protein FtsW FIU26_02330 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FIU26_02335 ENOG4105D4A Cell wall formation (By similarity) FIU26_02340 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) FIU26_02345 ENOG4108R2U division initiation protein FIU26_02355 ENOG4105K67 small basic protein FIU26_02360 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FIU26_02365 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FIU26_02375 ENOG4105FFI sigma-e processing peptidase spoiiga FIU26_02380 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU26_02390 ENOG4105DKW ABC transporter FIU26_02400 ENOG4105WR5 sporulation protein, YlmC YmxH family FIU26_02405 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FIU26_02410 ENOG4105DFA alanine racemase domain protein FIU26_02415 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) FIU26_02420 ENOG41067XK integral membrane protein FIU26_02425 ENOG4105DBK s4 domain protein FIU26_02435 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FIU26_02445 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) FIU26_02450 ENOG4105C34 Pseudouridine synthase FIU26_02455 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) FIU26_02465 ENOG4105CXT aspartate transcarbamylase FIU26_02475 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FIU26_02480 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FIU26_02485 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) FIU26_02490 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) FIU26_02495 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) FIU26_02500 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FIU26_02505 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) FIU26_02515 ENOG4107S4M Sulfate adenylate transferase FIU26_02520 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) FIU26_02525 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FIU26_02530 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FIU26_02535 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FIU26_02540 ENOG4105F23 Fibronectin-binding protein FIU26_02550 ENOG4105DSJ YicC domain protein FIU26_02555 ENOG4105KC4 UPF0296 protein FIU26_02560 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FIU26_02570 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FIU26_02575 ENOG4105C25 Primosomal protein n' FIU26_02580 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FIU26_02585 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) FIU26_02590 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FIU26_02595 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs FIU26_02600 ENOG4108ZF3 Phosphatase FIU26_02605 ENOG4105D9P serine threonine protein kinase FIU26_02610 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FIU26_02615 ENOG4105DJV ribulose-phosphate 3-epimerase FIU26_02620 ENOG4105FJ0 thiamine FIU26_02630 ENOG4105VB9 50S ribosomal protein l28 FIU26_02635 ENOG4108ZAA Alkaline-shock protein FIU26_02640 ENOG4105DP4 dak2 domain fusion protein ylov FIU26_02650 ENOG4105EJQ L-serine dehydratase FIU26_02655 ENOG4105CB5 ATP-dependent DNA helicase recG FIU26_02660 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) FIU26_02670 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FIU26_02675 ENOG4105CHR reductase FIU26_02680 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FIU26_02685 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) FIU26_02690 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FIU26_02695 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FIU26_02710 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) FIU26_02720 ENOG4105K5M 30s ribosomal protein S16 FIU26_02725 ENOG4108BW8 UPF0109 protein FIU26_02735 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) FIU26_02740 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) FIU26_02745 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FIU26_02755 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FIU26_02765 ENOG4105VM1 flagellar FIU26_02770 ENOG4105CMV Succinyl-CoA synthetase subunit beta FIU26_02775 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FIU26_02780 ENOG4105C79 DNA protecting protein DprA FIU26_02785 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FIU26_02790 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) FIU26_02795 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FIU26_02800 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) FIU26_02815 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FIU26_02820 ENOG4108ZC9 flagellar basal-body rod protein flgc FIU26_02825 ENOG4105VQ0 flagellar hook-basal body complex protein fliE FIU26_02830 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) FIU26_02835 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FIU26_02850 ENOG4106YF4 Flagellar biosynthesis chaperone FIU26_02860 ENOG410696Y Flagellar hook-length control protein FIU26_02865 ENOG410822I Flagellar hook capping protein FIU26_02870 ENOG4108JQA flagellar FIU26_02875 ENOG41068WV flagellar FlbD family protein FIU26_02885 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FIU26_02890 ENOG4105DD5 Flagellar motor switch protein FIU26_02895 ENOG4107YTP response regulator receiver protein FIU26_02905 ENOG4105CN7 Flagellar biosynthetic protein FliP FIU26_02910 ENOG4105VS8 Flagellar biosynthetic protein fliq FIU26_02915 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FIU26_02920 ENOG4105D00 flagellar biosynthetic protein flhB FIU26_02925 ENOG4105D7B Flagellar biosynthesis protein flha FIU26_02930 ENOG4105FZW flagellar biosynthesis regulator FlhF FIU26_02940 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FIU26_02945 ENOG4105CBS Chea signal transduction histidine kinase FIU26_02950 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis FIU26_02965 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU26_02975 ENOG4105CE9 30S ribosomal protein S2 FIU26_02980 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) FIU26_02990 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) FIU26_02995 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FIU26_03000 ENOG4105KNE Phosphatidate cytidylyltransferase FIU26_03010 ENOG4105DZP Membrane-associated zinc metalloprotease FIU26_03015 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) FIU26_03020 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FIU26_03025 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) FIU26_03030 ENOG4105CHV Transcription elongation factor NusA FIU26_03035 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination FIU26_03040 ENOG4105VHM ribosomal protein FIU26_03045 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) FIU26_03050 ENOG4105W7A Protein of unknown function (DUF503) FIU26_03055 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) FIU26_03060 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FIU26_03065 ENOG4105DTN riboflavin biosynthesis protein ribF FIU26_03070 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) FIU26_03075 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FIU26_03085 ENOG4105C1V Peptidase, M16 FIU26_03095 ENOG4105E35 Dipicolinate synthase subunit A FIU26_03100 ENOG4108S0H Dipicolinic acid synthetase, b subunit FIU26_03105 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FIU26_03115 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FIU26_03125 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit FIU26_03135 ENOG4105CNU cell division protein FtsK FIU26_03140 ENOG4105FDP GntR family transcriptional regulator FIU26_03160 ENOG4108RKS Short-chain dehydrogenase reductase Sdr FIU26_03165 ENOG4105XZV Protein of unknown function (DUF3243) FIU26_03180 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FIU26_03185 ENOG4105CEV competence damage-inducible protein FIU26_03195 ENOG4108A04 Beta-lactamase FIU26_03200 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) FIU26_03205 ENOG4105D48 metallophosphoesterase FIU26_03210 ENOG4105MCT stage V sporulation protein S FIU26_03220 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FIU26_03225 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FIU26_03240 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) FIU26_03245 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FIU26_03260 ENOG4105IIP Membrane FIU26_03265 ENOG4105W1N transcriptional regulator FIU26_03270 ENOG4108151 Beta-lactamase domain protein FIU26_03280 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FIU26_03290 ENOG4107QKG PfaD family FIU26_03295 ENOG41062T2 Acyl carrier protein FIU26_03300 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase FIU26_03305 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase FIU26_03310 ENOG4108MGH Enoyl-CoA hydratase FIU26_03315 ENOG4108KQ6 Enoyl-CoA hydratase FIU26_03320 ENOG4105C0W non-ribosomal peptide synthetase FIU26_03325 ENOG4107SQU synthase FIU26_03335 ENOG4105C0W non-ribosomal peptide synthetase FIU26_03345 ENOG4106A3M Cytochrome p-450 FIU26_03360 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FIU26_03370 ENOG4105K7W phage-related replication protein FIU26_03375 ENOG4108X3M OsmC Ohr family protein FIU26_03400 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) FIU26_03405 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FIU26_03420 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FIU26_03425 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FIU26_03430 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FIU26_03435 ENOG4105U6W MutT NUDIX family protein FIU26_03440 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FIU26_03450 ENOG4106F1P AAA ATPase, central domain protein FIU26_03455 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FIU26_03460 ENOG4105CXI aluminum resistance protein FIU26_03465 ENOG4105KV4 Transcriptional regulator FIU26_03470 ENOG4105C5F glutamine synthetase FIU26_03495 ENOG4105CT4 transporter FIU26_03500 ENOG4105DSG hydrolase family 43 FIU26_03515 ENOG4105CMG Carbohydrate kinase FIU26_03530 ENOG4105C54 Major Facilitator superfamily FIU26_03535 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FIU26_03545 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) FIU26_03610 ENOG4105CAH Chromate FIU26_03630 ENOG4105FVX FIU26_03640 ENOG4105K7W phage-related replication protein FIU26_03650 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) FIU26_03665 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FIU26_03675 ENOG4108SVB resolvase FIU26_03680 ENOG4105VPS UPF0291 protein FIU26_03685 ENOG4105CV1 Transketolase (EC 2.2.1.1) FIU26_03705 ENOG4107QIV Cytochrome c biogenesis protein FIU26_03730 ENOG4107DZX Small, acid-soluble spore protein P FIU26_03740 ENOG4108I0Z Aconitate hydratase FIU26_03745 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FIU26_03760 ENOG41067CD Small, acid-soluble spore protein Tlp FIU26_03770 ENOG4105MI2 FIU26_03775 ENOG4105W8X HesB YadR YfhF-family protein FIU26_03780 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) FIU26_03785 ENOG4105K4P CoA-binding domain protein FIU26_03790 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FIU26_03810 ENOG4107QWR cellulase (EC 3.2.1.4) FIU26_03825 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FIU26_03830 ENOG4107T5V SNARE associated Golgi FIU26_03870 ENOG4107QX3 carboxylase FIU26_03875 ENOG4105E39 Enoyl-CoA hydratase FIU26_03880 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FIU26_03885 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FIU26_03890 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FIU26_03895 ENOG4105CEY Amp-dependent synthetase and ligase FIU26_03900 ENOG4105C1G acyl-Coa dehydrogenase FIU26_03915 ENOG4105F32 YngK protein FIU26_03920 ENOG4106U2H Protein of unknown function (DUF1360) FIU26_03945 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family FIU26_03950 ENOG4108N2V aldose 1-epimerase FIU26_03955 ENOG4107QJQ Mate efflux family protein FIU26_03980 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase FIU26_04005 ENOG41068G1 FIU26_04015 ENOG410651K Teichoic acid biosynthesis protein C FIU26_04020 ENOG4108S4A n-acetylmuramoyl-l-alanine amidase FIU26_04250 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FIU26_04265 ENOG4105BZ8 glutamate synthase FIU26_04270 ENOG4105CBC glutamate synthase FIU26_04275 ENOG4105C5Q Transcriptional regulator FIU26_04280 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FIU26_04310 ENOG4108UB7 FIU26_04315 ENOG41068WN FIU26_04340 ENOG4105IE8 Alpha-ketoglutarate permease FIU26_04345 ENOG4107U6E carbohydrate kinase FGGY FIU26_04350 ENOG4108M3J Dehydrogenase FIU26_04355 ENOG4108J2R molybdopterin oxidoreductase FIU26_04385 ENOG4105EC8 Methyl-accepting chemotaxis FIU26_04395 ENOG4108YQE rare lipoprotein a FIU26_04400 ENOG4105XPP Protein of unknown function (DUF1275) FIU26_04405 ENOG4108NR7 pectate lyase FIU26_04425 ENOG4108RAV Conserved protein FIU26_04465 ENOG41073R8 VanW family FIU26_04475 ENOG4105VMP Transcriptional regulator FIU26_04480 ENOG4105NX3 Membrane FIU26_04490 ENOG4108Q5Y Membrane FIU26_04515 ENOG4108V4B ThiJ pfpI FIU26_04520 ENOG4108J4B Beta-lactamase FIU26_04530 ENOG4108M1A Chitin-binding protein FIU26_04560 ENOG4108SHN Glycosyl transferase, family 2 FIU26_04565 ENOG4106WTF Glycosyl transferase, family 2 FIU26_04605 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FIU26_04625 ENOG4108RZ2 Glycoside hydrolase family 16 FIU26_04645 ENOG4108Z7R Chaperone CsaA FIU26_04650 ENOG4105FTV AraC Family Transcriptional Regulator FIU26_04655 ENOG4108HJF gCN5-related N-acetyltransferase FIU26_04675 ENOG4105D29 Helix-turn-helix type 11 domain protein FIU26_04685 ENOG4105KTU Transcriptional regulator, arsr family FIU26_04695 ENOG4108SJC Membrane FIU26_04715 ENOG4105ECK Fatty Acid Desaturase FIU26_04720 ENOG4108ZGX Histidine kinase FIU26_04725 ENOG4108S01 response regulator FIU26_04730 ENOG4107RUZ Sss sodium solute transporter superfamily FIU26_04735 ENOG41069ER domain protein FIU26_04740 ENOG4105C9U ATP-dependent DNA helicase RecQ FIU26_04750 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FIU26_04755 ENOG4105SCY DNAK suppressor FIU26_04770 ENOG4105C26 Dehydrogenase FIU26_04775 ENOG4105EWU Squalene--hopene cyclase FIU26_04780 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FIU26_04785 ENOG4105C8J )-transporter FIU26_04790 ENOG4105C09 Bile acid FIU26_04795 ENOG4105C7S Dehydrogenase FIU26_04805 ENOG4107T89 von Willebrand factor, type A FIU26_04810 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FIU26_04820 ENOG4105K4H Nlp p60 protein FIU26_04825 ENOG41087PP glycosyltransferase MGT family FIU26_04835 ENOG4107QMU Mate efflux family protein FIU26_04840 ENOG4106SCS STAS domain FIU26_04860 ENOG4105FR1 rard protein FIU26_04875 ENOG41090U3 tautomerase FIU26_04895 ENOG4105FBA Phospholipase Carboxylesterase FIU26_04910 ENOG4105E1V na solute symporter FIU26_04930 ENOG4108VXD carboxy-peptidase FIU26_04935 ENOG4105D3A purine nucleoside phosphorylase DeoD-type FIU26_04945 ENOG4106Z5R FIU26_04950 ENOG410841Q phosphoesterase PA-phosphatase related protein FIU26_04985 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FIU26_04990 ENOG4108TSC N-acetyltransferase FIU26_04995 ENOG4107S4Y M20 DapE family protein YgeY FIU26_05010 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FIU26_05050 ENOG4107T32 3-phytase (EC 3.1.3.8) FIU26_05055 ENOG4105C5E polysaccharide biosynthesis protein FIU26_05060 ENOG4105E0X reductase FIU26_05065 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FIU26_05085 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) FIU26_05090 ENOG41090WU lipolytic protein G-D-S-L family FIU26_05095 ENOG4108KF3 Electron transport protein SCO1 SenC FIU26_05105 ENOG4105C7B Threonine dehydratase FIU26_05115 ENOG4108UT2 hemolysin iii FIU26_05125 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FIU26_05145 ENOG4107YX5 Pfam:DUF548 FIU26_05150 ENOG4108Y6J UPF0403 protein FIU26_05155 ENOG4105C01 Dihydroxy-acid dehydratase FIU26_05170 ENOG4108V06 Glutathione peroxidase FIU26_05175 ENOG4105CVG Homoserine O-transsuccinylase FIU26_05220 ENOG41081VK Ribonuclease FIU26_05245 ENOG410890F Dynamin family FIU26_05260 ENOG41065KQ synthase FIU26_05265 ENOG4105C2W permease FIU26_05270 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) FIU26_05275 ENOG4105CTD carboxy-peptidase FIU26_05280 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) FIU26_05285 ENOG4108UHU Aldolase FIU26_05290 ENOG4105D7K pfkb domain protein FIU26_05295 ENOG4108M60 Transcriptional regulator FIU26_05305 ENOG4105CHR reductase FIU26_05310 ENOG4105DVT helicase FIU26_05325 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FIU26_05340 ENOG4108UKS UPF0398 protein FIU26_05355 ENOG4107X2U Inherit from COG: Exonuclease-like protein FIU26_05360 ENOG4108I5C dEAD DEAH box helicase FIU26_05410 ENOG4105BZ4 penicillin-binding protein FIU26_05420 ENOG4105CSM endonuclease III FIU26_05430 ENOG4105C5S asparaginyl-tRNA synthetase FIU26_05435 ENOG4105CHM Aminotransferase FIU26_05445 ENOG4105YAC FIU26_05450 ENOG4105DVT helicase FIU26_05455 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) FIU26_05460 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) FIU26_05465 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) FIU26_05475 ENOG4105DJ0 Poly(A) Polymerase FIU26_05480 ENOG4105CPK Glycosyl transferase (Group 1 FIU26_05485 ENOG4105FJR Lmbe family FIU26_05490 ENOG4108Z5K methylglyoxal synthase FIU26_05495 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) FIU26_05500 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase FIU26_05505 ENOG4108JYZ YitT family FIU26_05525 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FIU26_05545 ENOG41068YB TPR repeat-containing protein FIU26_05555 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase FIU26_05565 ENOG4105CIH Imidazole acetol-phosphate transaminase FIU26_05575 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FIU26_05580 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase FIU26_05590 ENOG4108I0Q anthranilate phosphoribosyltransferase FIU26_05595 ENOG4105CRQ synthase (Component I) FIU26_05600 ENOG4105KHN chorismate mutase FIU26_05605 ENOG4105D49 3-dehydroquinate synthase FIU26_05610 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase FIU26_05615 ENOG4105BZU Histidine kinase FIU26_05620 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) FIU26_05625 ENOG4105EAH synthase FIU26_05630 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FIU26_05635 ENOG4105XXQ heptaprenyl diphosphate synthase component I FIU26_05645 ENOG4105EUJ GTP cyclohydrolase i FIU26_05650 ENOG4105K70 DNA-binding protein FIU26_05655 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) FIU26_05670 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase FIU26_05675 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FIU26_05680 ENOG41065D1 FIU26_05685 ENOG4105S2F FIU26_05700 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) FIU26_05705 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FIU26_05710 ENOG4105CAT Cytidine monophosphate kinase FIU26_05725 ENOG4105MSI germination protein ypeb FIU26_05735 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) FIU26_05740 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase FIU26_05755 ENOG4107RGJ metallophosphoesterase FIU26_05770 ENOG4105I7S Abortive infection protein FIU26_05775 ENOG4105C9U ATP-dependent DNA helicase RecQ FIU26_05780 ENOG4105T7X FIU26_05790 ENOG4108SAX Membrane FIU26_05795 ENOG4108JQ1 Dehydrogenase FIU26_05800 ENOG4105FF2 Type I DHQase FIU26_05815 ENOG4105BZU Histidine kinase FIU26_05820 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FIU26_05825 ENOG4105CRE cytochrome C FIU26_05830 ENOG4107TWT Cytochrome c biogenesis protein FIU26_05840 ENOG4105FE9 pseudouridine synthase FIU26_05850 ENOG4108JIC nucleoside recognition domain protein FIU26_05855 ENOG4105DZ1 carboxypeptidase FIU26_05865 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FIU26_05870 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FIU26_05885 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FIU26_05890 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FIU26_05895 ENOG4108R6K riboflavin synthase, subunit alpha FIU26_05900 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FIU26_05910 ENOG4105C3F Signal peptidase i FIU26_05920 ENOG4105VES Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) FIU26_05930 ENOG4107ZE5 PPIases accelerate the folding of proteins FIU26_05940 ENOG4105PTM secreted protein FIU26_05945 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FIU26_05955 ENOG4105G6R Stage v sporulation protein ae FIU26_05965 ENOG4105CZ3 stage V sporulation protein ad FIU26_05970 ENOG41090VF Stage v sporulation protein ac FIU26_05985 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU26_05990 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) FIU26_05995 ENOG41082AN stage II sporulation protein FIU26_06000 ENOG4105DZ1 carboxypeptidase FIU26_06005 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) FIU26_06010 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FIU26_06015 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FIU26_06025 ENOG4105I3K Ferric uptake regulator, Fur family FIU26_06030 ENOG4105MZ9 stage II sporulation protein m FIU26_06045 ENOG4105DFD Na H antiporter FIU26_06050 ENOG4108IJ0 Aspartate ammonia-lyase FIU26_06055 ENOG4105HDK L-asparaginase FIU26_06060 ENOG4108IMY Transcriptional regulator FIU26_06080 ENOG4108YZ4 nudix hydrolase FIU26_06090 ENOG4105CPC Aldo Keto reductase FIU26_06105 ENOG4105CNI cell division protein FtsW FIU26_06110 ENOG4105CNI cell division protein FtsW FIU26_06125 ENOG4106HZJ FIU26_06130 ENOG4105RHY Pfam:UPF0157 FIU26_06135 ENOG4105KAC Antibiotic biosynthesis monooxygenase FIU26_06140 ENOG4108XET gCN5-related N-acetyltransferase FIU26_06150 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FIU26_06165 ENOG4105E5W Transporter FIU26_06170 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase FIU26_06185 ENOG4108IXY short-chain dehydrogenase reductase FIU26_06190 ENOG41069FQ Metallo-beta-lactamase superfamily FIU26_06195 ENOG4105II7 pyrroline-5-carboxylate reductase FIU26_06205 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FIU26_06220 ENOG410861F 50S ribosomal protein L33 FIU26_06225 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FIU26_06230 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FIU26_06235 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FIU26_06240 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FIU26_06250 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) FIU26_06255 ENOG4108NA0 Uncharacterized conserved protein (COG2071) FIU26_06260 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FIU26_06265 ENOG4108HNZ carboxyl transferase FIU26_06270 ENOG4108ZVT methylmalonyl-coA epimerase FIU26_06275 ENOG4108VZI ErfK ybiS ycfS ynhG family protein FIU26_06280 ENOG4108QEG Membrane FIU26_06285 ENOG4105CDA abc transporter atp-binding protein FIU26_06290 ENOG4105E5Q amino acid AbC transporter FIU26_06295 ENOG4108HW3 (ABC) transporter FIU26_06300 ENOG4108Y6J UPF0403 protein FIU26_06305 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FIU26_06320 ENOG4105C7S Dehydrogenase FIU26_06325 ENOG4105CPP Dehydrogenase, E1 component FIU26_06340 ENOG4105CKM Branched-chain carboxylic acid kinase FIU26_06345 ENOG4107RDP Dehydrogenase FIU26_06355 ENOG4108JUB Transcriptional regulator FIU26_06360 ENOG4106CCJ Protein of unknown function (DUF2627) FIU26_06365 ENOG4105CR4 methylisocitrate lyase FIU26_06370 ENOG4105DXD 2-methylcitrate dehydratase FIU26_06380 ENOG4105C1G acyl-Coa dehydrogenase FIU26_06385 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FIU26_06395 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FIU26_06400 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FIU26_06415 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FIU26_06420 ENOG4107QQR Sporulation FIU26_06430 ENOG4105S1Z Stage IV sporulation protein B FIU26_06435 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FIU26_06440 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) FIU26_06445 ENOG4105DX0 Hemolysin A FIU26_06455 ENOG4105CTB Polyprenyl synthetase FIU26_06460 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FIU26_06465 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FIU26_06470 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) FIU26_06475 ENOG4105M7K Involved in the transcription termination process (By similarity) FIU26_06480 ENOG4108ZSR alkaline shock protein FIU26_06485 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FIU26_06505 ENOG410644B Stage III sporulation protein af FIU26_06515 ENOG4105KQ4 Stage iii sporulation protein ad FIU26_06520 ENOG4108CQH stage III sporulation protein AC FIU26_06525 ENOG4105KR5 Stage iii sporulation protein FIU26_06530 ENOG4105CD2 stage iii sporulation protein aa FIU26_06540 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FIU26_06545 ENOG4105DC7 peptidase M24 FIU26_06550 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) FIU26_06560 ENOG4105CBJ Metal-dependent enzyme FIU26_06575 ENOG4105KST dependent repressor FIU26_06580 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FIU26_06585 ENOG4105WZW rhodanese family FIU26_06590 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor FIU26_06595 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor FIU26_06600 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) FIU26_06605 ENOG4105C0D helicase FIU26_06625 ENOG4108IMY Transcriptional regulator FIU26_06635 ENOG4105VFR signal peptidase FIU26_06695 ENOG41080XP Cbs domain FIU26_06705 ENOG4105C37 (CBS) domain FIU26_06730 ENOG4105C5X domain protein FIU26_06755 ENOG4105E0M Sulfatase FIU26_06770 ENOG4107ZXI Rhomboid family FIU26_06780 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FIU26_06785 ENOG4105WDJ 50S ribosomal protein L33 FIU26_06805 ENOG41068DG YceG-like family FIU26_06810 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FIU26_06815 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FIU26_06820 ENOG4105E2Z phosphate ABC transporter (Permease FIU26_06825 ENOG4105C8U phosphate abc transporter FIU26_06830 ENOG4105CVA phosphate FIU26_06835 ENOG4107RF6 penicillin-binding protein FIU26_06845 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FIU26_06850 ENOG4105SXS Protein of unknown function (DUF456) FIU26_06865 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) FIU26_06870 ENOG41063Y9 FIU26_06875 ENOG4108U5J '-nucleotidase FIU26_06880 ENOG4105N80 Ferric uptake regulator, Fur family FIU26_06885 ENOG4108JYZ YitT family FIU26_06890 ENOG41069ZM Protein of unknown function (DUF2624) FIU26_06895 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) FIU26_06910 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) FIU26_06915 ENOG4105EGD dinuclear metal center protein, YbgI family FIU26_06930 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU26_06935 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FIU26_06940 ENOG41082VT Uncharacterized BCR, YaiI/YqxD family COG1671 FIU26_06945 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) FIU26_06955 ENOG4105C38 Glycyl-tRNA synthetase beta subunit FIU26_06960 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit FIU26_06965 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) FIU26_06975 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FIU26_06980 ENOG4105KG3 cytidine deaminase FIU26_06985 ENOG4107YR5 Diacylglycerol kinase FIU26_06990 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) FIU26_06995 ENOG4105CTJ Metal Dependent Phosphohydrolase FIU26_07000 ENOG4105C9A Phoh family FIU26_07005 ENOG4105EI1 sporulation protein yqfd FIU26_07010 ENOG41068P3 sporulation protein YqfC FIU26_07020 ENOG4105DI5 UPF0365 protein FIU26_07025 ENOG4105F7J membrane-bound serine protease FIU26_07030 ENOG4105KTH gatB Yqey FIU26_07045 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FIU26_07050 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FIU26_07055 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) FIU26_07065 ENOG4105CFG Acts as a chaperone (By similarity) FIU26_07070 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ FIU26_07075 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) FIU26_07080 ENOG4105CSA Coproporphyrinogen iii oxidase FIU26_07085 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) FIU26_07095 ENOG4108ZRV stage ii sporulation protein p FIU26_07100 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) FIU26_07105 ENOG41082YS Binds directly to 16S ribosomal RNA FIU26_07110 ENOG4105TQK DNA polymerase iii, delta' subunit FIU26_07125 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FIU26_07130 ENOG4108UK2 deaminase FIU26_07135 ENOG4105KQC Competence protein FIU26_07145 ENOG4108D32 Methyltransferase FIU26_07155 ENOG4108WF2 Metal Dependent Phosphohydrolase FIU26_07160 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) FIU26_07165 ENOG410812S Rna-binding protein FIU26_07170 ENOG4105E2X shikimate dehydrogenase FIU26_07175 ENOG4105CQW ribosome biogenesis GTPase YqeH FIU26_07180 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FIU26_07200 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FIU26_07205 ENOG41080BT SNARE associated Golgi FIU26_07220 ENOG4105WFK nuclease FIU26_07225 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU26_07230 ENOG4107Y5K Resolvase FIU26_07240 ENOG4105C9Q fumarate hydratase class II FIU26_07245 ENOG4107RSM transcriptional regulator FIU26_07265 ENOG4105EA8 2-Nitropropane dioxygenase FIU26_07270 ENOG4105K56 Transcriptional regulator FIU26_07280 ENOG4105KVH Transcriptional regulator FIU26_07285 ENOG4108DBC nitroreductase FIU26_07290 ENOG4108R6W Transcriptional regulator, ARAC family FIU26_07300 ENOG4105EMU Dehydrogenase FIU26_07310 ENOG41090E6 transcriptional regulator MERR family FIU26_07320 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FIU26_07330 ENOG41073TP transcriptional regulator FIU26_07340 ENOG4105CTQ phosphohexokinase FIU26_07345 ENOG4105CTQ phosphohexokinase FIU26_07360 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) FIU26_07365 ENOG4108HHA Transketolase FIU26_07380 ENOG4105WAB arsR family transcriptional regulator FIU26_07395 ENOG4105BZG amino acid carrier protein FIU26_07405 ENOG4105UNS Pfam:DUF419 FIU26_07420 ENOG4108MEK Metal-binding protein YodA FIU26_07425 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein FIU26_07430 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein FIU26_07440 ENOG4105PGS Spore coat protein FIU26_07445 ENOG4105E2A Dehydrogenase FIU26_07460 ENOG4105KRI phosphocarrier protein (HPr FIU26_07465 ENOG4105CPC Aldo Keto reductase FIU26_07470 ENOG4105CF7 AraC family transcriptional regulator FIU26_07475 ENOG4105VUF Transcriptional regulator FIU26_07480 ENOG4105VUF Transcriptional regulator FIU26_07485 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) FIU26_07490 ENOG4105DQ4 alcohol dehydrogenase FIU26_07495 ENOG4108Z0Z intracellular protease Pfpi family FIU26_07500 ENOG4108HKT sucrose-6-phosphate hydrolase FIU26_07510 ENOG4105F3R pts system mannose fructose sorbose family iid FIU26_07515 ENOG4105ETZ PTS System FIU26_07520 ENOG4108IQ3 PTS system FIU26_07525 ENOG4105YHU PTS system FIU26_07530 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FIU26_07545 ENOG4105C85 amino acid FIU26_07550 ENOG4105N14 lysine exporter protein LysE YggA FIU26_07555 ENOG4108NGU Transcriptional regulator FIU26_07560 ENOG4105JVQ RNA Polymerase FIU26_07565 ENOG4108P49 AntiSigma factor FIU26_07570 ENOG4105EXC Acyl-transferase FIU26_07575 ENOG4105WDR FIU26_07580 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FIU26_07585 ENOG41082JN Transcriptional regulator FIU26_07605 ENOG4105TMB Formate nitrite transporter FIU26_07610 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) FIU26_07615 ENOG4108JB9 formate dehydrogenase FIU26_07630 ENOG4105C28 cystathionine FIU26_07645 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) FIU26_07660 ENOG4107XRG penicillin-binding protein FIU26_07665 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FIU26_07670 ENOG4105DBI uridine monophosphokinase FIU26_07675 ENOG4105CFP Peptidase U32 FIU26_07680 ENOG4105XYU peptidase (U32 family) FIU26_07685 ENOG4108VQJ O-methyltransferase FIU26_07690 ENOG4105HHA aminodeoxychorismate lyase FIU26_07695 ENOG4105VPH UPF0473 protein FIU26_07700 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) FIU26_07705 ENOG4105VBH UPF0297 protein FIU26_07710 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FIU26_07715 ENOG4105C02 permease FIU26_07725 ENOG41060CR FIU26_07735 ENOG4105C7H Helicase, RecD TraA family FIU26_07745 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FIU26_07750 ENOG4105C3J Cysteine desulfurase FIU26_07760 ENOG4105D1H recombination factor protein RarA FIU26_07770 ENOG4105CUZ uba thif-type nad fad binding protein FIU26_07780 ENOG4105C9M aspartyl-trna synthetase FIU26_07785 ENOG4105CUT histidyl-tRNA synthetase FIU26_07795 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FIU26_07805 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FIU26_07810 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) FIU26_07815 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FIU26_07820 ENOG41067VP Protein of unknown function (DUF1049) FIU26_07825 ENOG4105NCW Trka-c domain protein FIU26_07830 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FIU26_07840 ENOG4105CKP Polysaccharide Biosynthesis Protein FIU26_07845 ENOG4108QG2 Membrane FIU26_07850 ENOG4105NAP FIU26_07855 ENOG4105VIE preprotein translocase, subunit YajC FIU26_07860 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) FIU26_07865 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) FIU26_07870 ENOG41061AI Protein of unknown function (DUF2905) FIU26_07875 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) FIU26_07880 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) FIU26_07890 ENOG4105IE8 Alpha-ketoglutarate permease FIU26_07895 ENOG4105CK5 oxidoreductase FIU26_07910 ENOG4105BZG amino acid carrier protein FIU26_07915 ENOG4105CDY transcriptional regulatory protein FIU26_07925 ENOG4106678 morphogenetic protein associated with SpoVID FIU26_07930 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) FIU26_07935 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FIU26_07940 ENOG4108IYU L-aspartate oxidase FIU26_07955 ENOG4105CQC Prephenate dehydratase FIU26_07960 ENOG41090I5 UPF0735 ACT domain-containing protein FIU26_07965 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FIU26_07980 ENOG4105K46 50S ribosomal protein l27 FIU26_07985 ENOG4105X36 (ribosomal) protein FIU26_07990 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) FIU26_08005 ENOG4107QMS site-determining protein FIU26_08010 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) FIU26_08015 ENOG4105YHC Rod shape-determining protein MreD FIU26_08020 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FIU26_08025 ENOG4105DFF Rod shape-determining protein mreb FIU26_08030 ENOG4105W5Q DNA repair protein (RadC FIU26_08035 ENOG4108Z03 MAF-like protein FIU26_08045 ENOG4106A3R peptidase FIU26_08050 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FIU26_08055 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FIU26_08065 ENOG4106AR7 Spore coat protein FIU26_08070 ENOG41068KH stage VI sporulation protein D FIU26_08075 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase FIU26_08080 ENOG4105D52 delta-aminolevulinic acid dehydratase FIU26_08090 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) FIU26_08100 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) FIU26_08110 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) FIU26_08115 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FIU26_08120 ENOG4108IUQ atp-dependent protease FIU26_08125 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) FIU26_08130 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FIU26_08140 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FIU26_08145 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FIU26_08150 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FIU26_08155 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) FIU26_08160 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FIU26_08165 ENOG4108ZP8 Acetolactate synthase small subunit FIU26_08170 ENOG4105C7K acetolactate synthase FIU26_08180 ENOG4105I4A GCN5-related N-acetyltransferase FIU26_08190 ENOG4107KM7 Heat induced stress protein YflT FIU26_08200 ENOG4105M59 Phosphodiesterase, mj0936 family FIU26_08205 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FIU26_08210 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) FIU26_08215 ENOG4108XJQ germination protein FIU26_08220 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FIU26_08225 ENOG41067TZ transcriptional regulator, MarR family FIU26_08230 ENOG4105PFC Transcriptional regulator FIU26_08240 ENOG4105E33 succinate dehydrogenase FIU26_08250 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit FIU26_08260 ENOG4105CFH Aspartokinase FIU26_08270 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FIU26_08275 ENOG4105K63 Thioredoxin FIU26_08285 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) FIU26_08290 ENOG4105C10 Electron transfer flavoprotein FIU26_08295 ENOG4105BZJ Electron transfer flavoprotein FIU26_08300 ENOG41060WC Enoyl-CoA hydratase FIU26_08305 ENOG4107Z3H Transcriptional regulator, TetR family FIU26_08310 ENOG4105CEY Amp-dependent synthetase and ligase FIU26_08320 ENOG4105C98 muts2 protein FIU26_08325 ENOG4105DCG PHP domain protein FIU26_08340 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FIU26_08345 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FIU26_08350 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) FIU26_08360 ENOG4108RWN rrna methyltransferase FIU26_08365 ENOG41067MF small acid-soluble spore protein FIU26_08370 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FIU26_08375 ENOG4105D2K citrate carrier protein FIU26_08380 ENOG4105CQB FAD linked oxidase domain protein FIU26_08385 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FIU26_08415 ENOG4105K7K Transcriptional regulator FIU26_08420 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) FIU26_08425 ENOG4105DRS transport system, permease FIU26_08440 ENOG4108MDK Dehydrogenase FIU26_08450 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FIU26_08455 ENOG4105EF1 ribulokinase FIU26_08465 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase FIU26_08470 ENOG4105CN9 Peptidase m42 family protein FIU26_08480 ENOG410696E Membrane FIU26_08485 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FIU26_08490 ENOG4105VJV 50s ribosomal protein L35 FIU26_08495 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FIU26_08510 ENOG41067MG lrgb family FIU26_08520 ENOG4105DY9 regulatoR FIU26_08525 ENOG4108HRK Histidine kinase FIU26_08530 ENOG4105U0R haloacid dehalogenase-like hydrolase FIU26_08535 ENOG4105C22 threonyL-tRNA synthetase FIU26_08540 ENOG4108TDW sporulation protein YtxC FIU26_08560 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) FIU26_08565 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) FIU26_08570 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FIU26_08575 ENOG4105KVH Transcriptional regulator FIU26_08580 ENOG4105F27 Major Facilitator FIU26_08585 ENOG4105CV8 reductase FIU26_08590 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FIU26_08600 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) FIU26_08605 ENOG4105C2M dna polymerase I FIU26_08610 ENOG4105BZU Histidine kinase FIU26_08615 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FIU26_08620 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FIU26_08625 ENOG4108HMX isocitrate dehydrogenase (NADP) FIU26_08630 ENOG4105BZN citrate synthase FIU26_08640 ENOG4108REF Sporulation integral membrane protein ytvi FIU26_08645 ENOG4105FS0 cytoplasmic membrane protein FIU26_08650 ENOG4105CA9 Pyruvate kinase FIU26_08655 ENOG4105CTQ phosphohexokinase FIU26_08665 ENOG4108IEY Carboxyl transferase domain FIU26_08670 ENOG4105C6K Malic enzyme FIU26_08675 ENOG4105C0B DNA polymerase III (alpha subunit) FIU26_08680 ENOG4105VV2 FIU26_08690 ENOG4106EVM FIU26_08695 ENOG4105SFS phosphoesterase RecJ domain protein FIU26_08710 ENOG4105E8R UPF0173 metal-dependent hydrolase FIU26_08725 ENOG4105CH7 arginosuccinase FIU26_08730 ENOG4105CDH Citrulline--aspartate ligase FIU26_08735 ENOG4105EPU Molybdenum cofactor synthesis domain protein FIU26_08740 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FIU26_08750 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FIU26_08755 ENOG4105KBJ sporulation protein ytfj FIU26_08765 ENOG4105VK3 rdd domain containing protein FIU26_08770 ENOG4105D07 Signal peptide peptidase, SppA FIU26_08775 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FIU26_08780 ENOG4105EFZ amidohydrolase FIU26_08785 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FIU26_08820 ENOG4105U5Y Transcriptional regulator FIU26_08830 ENOG4105BZU Histidine kinase FIU26_08840 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FIU26_08845 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FIU26_08855 ENOG4105F1V Acetoin utilization protein FIU26_08860 ENOG4105W87 Cbs domain FIU26_08865 ENOG4105DGU Histone deacetylase FIU26_08870 ENOG4105ER2 Ompa motb domain protein FIU26_08875 ENOG4107R0U MotA TolQ exbB proton channel FIU26_08880 ENOG4105ETE Transcriptional regulator (LacI family FIU26_08885 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FIU26_08905 ENOG4105DFU Cell wall formation (By similarity) FIU26_08915 ENOG4108VDD TRNA binding domain protein FIU26_08935 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ FIU26_08950 ENOG4105C6K Malic enzyme FIU26_08955 ENOG4105C8F Beta-lactamase domain protein FIU26_08960 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FIU26_08970 ENOG4108V15 phosphotransferase enzyme family FIU26_08975 ENOG4108IUM Glycogen debranching enzyme FIU26_08990 ENOG4107F58 2'-5' rna ligase FIU26_08995 ENOG4105C6T cysteine synthase FIU26_09000 ENOG4107QSE Dipeptidase FIU26_09005 ENOG4105C7N Xanthine uracil vitamin C permease FIU26_09020 ENOG4105YW5 deoR family transcriptional regulator FIU26_09035 ENOG4105CBX hi0933 family FIU26_09040 ENOG4105C94 Transporter FIU26_09050 ENOG4105MU9 integral membrane protein FIU26_09055 ENOG4105DDC Oxidoreductase domain protein FIU26_09065 ENOG4105F5H Glycosyl Hydrolase Family 88 FIU26_09075 ENOG41075H3 AraC family transcriptional regulator FIU26_09085 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FIU26_09095 ENOG4106A3M Cytochrome p-450 FIU26_09100 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) FIU26_09110 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FIU26_09115 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FIU26_09130 ENOG4105NTD Inherit from COG: Hydrolase FIU26_09145 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component FIU26_09150 ENOG4105I1K ABC transporter FIU26_09160 ENOG41085GJ domain protein FIU26_09165 ENOG4105C8T Leucyl-tRNA synthetase FIU26_09175 ENOG4105BZU Histidine kinase FIU26_09180 ENOG410605W Major Facilitator FIU26_09185 ENOG4106UBQ FIU26_09195 ENOG4105C19 ABC transporter FIU26_09200 ENOG4105EWM Histidine kinase FIU26_09210 ENOG4107R34 abc transporter permease protein FIU26_09215 ENOG4105C19 ABC transporter FIU26_09230 ENOG4105DVE abc transporter atp-binding protein FIU26_09235 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FIU26_09250 ENOG4105N5T Radical SAM Protein FIU26_09265 ENOG4105E8V Alpha Beta Hydrolase Fold protein FIU26_09270 ENOG4108Z0R Transferase FIU26_09275 ENOG4105C85 amino acid FIU26_09280 ENOG4105CAQ asparagine synthetase FIU26_09285 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP FIU26_09290 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase FIU26_09305 ENOG4105D2X ABC transporter substrate-binding protein FIU26_09315 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FIU26_09340 ENOG4108RMU ferritin dps family protein FIU26_09355 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) FIU26_09360 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) FIU26_09365 ENOG4108V2W Carbonate dehydratase FIU26_09390 ENOG4105CC5 ABC transporter FIU26_09395 ENOG4105CC5 ABC transporter FIU26_09400 ENOG4105DIK (ABC) transporter FIU26_09405 ENOG4105DSE periplasmic solute binding protein FIU26_09410 ENOG4105DTQ mandelate racemase muconate lactonizing FIU26_09415 ENOG4105CEY Amp-dependent synthetase and ligase FIU26_09420 ENOG4108IPT Naphthoate synthase FIU26_09425 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FIU26_09430 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) FIU26_09435 ENOG4105E4F Isochorismate synthase FIU26_09455 ENOG4108IAJ Nad-dependent epimerase dehydratase FIU26_09460 ENOG4107SBE Glycosyl transferase (Group 1 FIU26_09475 ENOG4107SBE Glycosyl transferase (Group 1 FIU26_09480 ENOG4108KS4 Spore coat protein FIU26_09495 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) FIU26_09505 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) FIU26_09635 ENOG4105N67 Proton-coupled thiamine transporter YuaJ FIU26_09640 ENOG4105VRR gCN5-related N-acetyltransferase FIU26_09645 ENOG4105DZ6 Band 7 protein FIU26_09655 ENOG4106DF1 FIU26_09660 ENOG4108VNY MOSC domain protein FIU26_09665 ENOG4108JB8 alcohol dehydrogenase FIU26_09670 ENOG4105C26 Dehydrogenase FIU26_09675 ENOG4105TRT Transcriptional regulator FIU26_09690 ENOG4105CZN Potassium uptake protein FIU26_09695 ENOG4107I77 yiaA/B two helix domain FIU26_09700 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FIU26_09720 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FIU26_09730 ENOG4105EE0 oxidoreductase FIU26_09735 ENOG4105DKG l-rhamnose isomerase FIU26_09740 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) FIU26_09745 ENOG4105DET Rhamnulokinase FIU26_09750 ENOG4105E98 transcriptional regulator DeoR family FIU26_09760 ENOG4105C8Q Methyl-accepting chemotaxis FIU26_09765 ENOG4105C8Q Methyl-accepting chemotaxis FIU26_09770 ENOG4105C8Q Methyl-accepting chemotaxis FIU26_09775 ENOG4105C8Q Methyl-accepting chemotaxis FIU26_09790 ENOG4105EA8 2-Nitropropane dioxygenase FIU26_09795 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FIU26_09810 ENOG4105C37 (CBS) domain FIU26_09825 ENOG4107PBV potassium channel FIU26_09830 ENOG4107PBV potassium channel FIU26_09845 ENOG4107QYV phosphohexose isomerase FIU26_09855 ENOG4107QW4 alcohol dehydrogenase FIU26_09860 ENOG4105WG9 Conserved Protein FIU26_09870 ENOG4105CHM Aminotransferase FIU26_09875 ENOG4108ZB6 transcriptional regulator AsnC family FIU26_09880 ENOG4108MUZ hydrolase FIU26_09890 ENOG4105C87 Aminotransferase class I and II FIU26_09895 ENOG4108HGU Histidine kinase FIU26_09900 ENOG4105Y38 Kinase-associated protein B FIU26_09920 ENOG4105BZ4 penicillin-binding protein FIU26_09925 ENOG4105KIR Thiol-disulfide oxidoreductase dcc FIU26_09940 ENOG4108MRH transcriptional regulatory protein FIU26_09955 ENOG4105D65 subunit l FIU26_09960 ENOG4105HC0 Na H antiporter FIU26_09965 ENOG4108ZE9 Monovalent cation H antiporter subunit C FIU26_09970 ENOG4108JPZ Monovalent cation H antiporter subunit D FIU26_09975 ENOG4105SC1 monovalent cation H antiporter subunit E FIU26_09985 ENOG4105KJM monovalent cation h antiporter subunit g FIU26_09990 ENOG4105KA0 thioesterase Superfamily protein FIU26_10000 ENOG4105BZU Histidine kinase FIU26_10030 ENOG4105D58 Diguanylate phosphodiesterase FIU26_10035 ENOG4105DAP Nicotinate phosphoribosyltransferase FIU26_10060 ENOG4105C02 permease FIU26_10080 ENOG410904N short-chain dehydrogenase reductase FIU26_10115 ENOG4108K8K Transcriptional regulator FIU26_10120 ENOG4105DCF alanine dehydrogenase FIU26_10130 ENOG4105WQT MbtH domain protein FIU26_10135 ENOG4105CEY Amp-dependent synthetase and ligase FIU26_10140 ENOG4105WQI isochorismatase FIU26_10145 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FIU26_10150 ENOG4105E4F Isochorismate synthase FIU26_10155 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FIU26_10160 ENOG4105NIV Esterase FIU26_10180 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) FIU26_10190 ENOG41069ER domain protein FIU26_10205 ENOG4105CEP NADH dehydrogenase FIU26_10210 ENOG4105CAY ferredoxin--nadp reductase FIU26_10265 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 FIU26_10275 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FIU26_10290 ENOG4105ZKE UPF0349 protein FIU26_10305 ENOG41083MR nifu domain-containing protein FIU26_10310 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein FIU26_10315 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) FIU26_10320 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) FIU26_10325 ENOG4105D6E homoserine dehydrogenase FIU26_10335 ENOG4108W5N phosphatidylglycerophosphatase a FIU26_10340 ENOG4105D4U had-superfamily hydrolase, subfamily iia FIU26_10350 ENOG4105MMD transcriptional regulator FIU26_10355 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FIU26_10360 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FIU26_10365 ENOG4105FAA peptidase M23 FIU26_10370 ENOG4108YTE sporulation protein YunB FIU26_10375 ENOG4105KZD Domain of unknown function (DUF1805) FIU26_10380 ENOG4107R8B 5'-nucleotidase FIU26_10390 ENOG4105I3N Conserved Protein FIU26_10400 ENOG4105CD3 dihydroorotase FIU26_10405 ENOG4105G9B Transcriptional regulator FIU26_10420 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) FIU26_10425 ENOG4105VT2 5-hydroxyisourate hydrolase FIU26_10440 ENOG4107YV9 domain protein FIU26_10445 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding FIU26_10460 ENOG4105XRQ Xanthine dehydrogenase accessory factor FIU26_10465 ENOG4105C5R Aminotransferase FIU26_10480 ENOG4108K8S endonuclease I FIU26_10485 ENOG4108IJ9 (ABC) transporter FIU26_10490 ENOG4105FDP GntR family transcriptional regulator FIU26_10495 ENOG4108KPW sugar kinase FIU26_10500 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FIU26_10505 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component FIU26_10510 ENOG4105XN3 extracellular solute-binding protein family 1 FIU26_10515 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine FIU26_10520 ENOG4105PKS Excinuclease abc c subunit domain protein FIU26_10525 ENOG4107VFR oxidoreductase FIU26_10540 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase FIU26_10545 ENOG4105NPE arsR family transcriptional regulator FIU26_10550 ENOG4105DIW FeS assembly protein SUFB FIU26_10555 ENOG4108UNV SUF system FeS assembly protein, NifU family FIU26_10560 ENOG4105C9B Cysteine desulfurase FIU26_10565 ENOG4105JRK feS assembly protein SufD FIU26_10570 ENOG4105C3K feS assembly ATPase SufC FIU26_10590 ENOG4105D01 (LipO)protein FIU26_10595 ENOG4108UMI ABC transporter, permease FIU26_10600 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FIU26_10625 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) FIU26_10630 ENOG41080E8 Transcriptional regulator, Spx MgsR family FIU26_10635 ENOG4105C1G acyl-Coa dehydrogenase FIU26_10640 ENOG4105CHU acetyl-coa acetyltransferase FIU26_10670 ENOG41067TZ transcriptional regulator, MarR family FIU26_10675 ENOG4105C0R drug resistance transporter emrb qaca subfamily FIU26_10680 ENOG4105MDS 4-oxalocrotonate tautomerase FIU26_10690 ENOG4105EGI Transcriptional regulator FIU26_10700 ENOG4105E0A ABC, transporter FIU26_10715 ENOG4105E1F short-chain dehydrogenase reductase FIU26_10720 ENOG4105HUF DNA protection during starvation protein FIU26_10725 ENOG4105C0H protease FIU26_10735 ENOG4105F3H Histidine kinase FIU26_10745 ENOG41067SE Tetr family transcriptional regulator FIU26_10750 ENOG4105C9Q fumarate hydratase class II FIU26_10775 ENOG4105WH1 Two component transcriptional regulator luxr family FIU26_10780 ENOG4105ENE Histidine kinase FIU26_10795 ENOG41087YS Phage shock protein A FIU26_10810 ENOG4108WBT adenosyltransferase FIU26_10815 ENOG4105E0A ABC, transporter FIU26_10820 ENOG4105EHG Permease protein FIU26_10825 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FIU26_10830 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FIU26_10835 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein FIU26_10845 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FIU26_10855 ENOG4106DF4 Sigma-70, region 4 FIU26_10865 ENOG4105F0F Oxalate decarboxylase FIU26_10875 ENOG4107RBB ABC transporter, permease FIU26_10880 ENOG4105C19 ABC transporter FIU26_10885 ENOG4108WMK Efflux transporter RND family MFP subunit FIU26_10890 ENOG4105E0A ABC, transporter FIU26_10895 ENOG4105EHG Permease protein FIU26_10900 ENOG4105DQ5 transport system permease protein FIU26_10915 ENOG4105D5Q Arginine ornithine antiporter FIU26_10930 ENOG4107K5X Membrane-bound metal-dependent hydrolase FIU26_10935 ENOG4107QZ2 Sulfatase FIU26_10940 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FIU26_10945 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FIU26_10950 ENOG4105E0C molybdate abc transporter FIU26_10965 ENOG4105EEQ Na H antiporter FIU26_10970 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FIU26_10975 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FIU26_10980 ENOG4105EEM helicase FIU26_10985 ENOG4105EN6 Membrane FIU26_10995 ENOG4107ZQN disulfide bond FIU26_11000 ENOG4105C59 p-type ATPase FIU26_11005 ENOG4105C59 p-type ATPase FIU26_11010 ENOG410681U heavy metal transport detoxification protein FIU26_11015 ENOG4105VPX protein, conserved in bacteria FIU26_11020 ENOG4105D9R oxidoreductase FIU26_11025 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FIU26_11030 ENOG4105ME7 Membrane FIU26_11035 ENOG4105DRR Transcriptional regulator, GntR family FIU26_11040 ENOG4108UZ3 Transporter FIU26_11045 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FIU26_11070 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) FIU26_11075 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FIU26_11085 ENOG4105XZU Preprotein translocase, subunit SecG FIU26_11110 ENOG4105KVH Transcriptional regulator FIU26_11135 ENOG4105DA5 (ABC) transporter FIU26_11165 ENOG4105R40 Glycine betaine carnitine choline FIU26_11170 ENOG4108HQR Glycine betaine FIU26_11175 ENOG4105E90 ABC transporter FIU26_11180 ENOG4108IJ8 ABC transporter FIU26_11185 ENOG4107HG4 Transcriptional regulator FIU26_11195 ENOG4105R40 Glycine betaine carnitine choline FIU26_11200 ENOG4108HQR Glycine betaine FIU26_11205 ENOG4105E90 ABC transporter FIU26_11210 ENOG4108IJ8 ABC transporter FIU26_11215 ENOG4107HG4 Transcriptional regulator FIU26_11220 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein FIU26_11235 ENOG4105T65 Membrane-associated protein FIU26_11240 ENOG4108W0I acetyltransferase FIU26_11245 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) FIU26_11250 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FIU26_11255 ENOG4105CP7 Triose-phosphate isomerase FIU26_11260 ENOG4105BZA Phosphoglycerate kinase FIU26_11270 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FIU26_11285 ENOG4105CMD Transcriptional regulator, GntR family FIU26_11290 ENOG4105DEN Luciferase family FIU26_11295 ENOG4107RT3 EamA-like transporter family FIU26_11305 ENOG4105VRS hydrolase family 18 FIU26_11310 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) FIU26_11315 ENOG4107QR9 Iron-sulfur cluster binding protein FIU26_11320 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FIU26_11340 ENOG4105BZU Histidine kinase FIU26_11345 ENOG4105KCT ABC transporter FIU26_11350 ENOG4108M15 ABC transporter FIU26_11355 ENOG4107R6F Alpha Beta Hydrolase Fold protein FIU26_11360 ENOG4108MJI response regulator FIU26_11375 ENOG4105EG2 ABC transporter, permease FIU26_11385 ENOG4107FKK extracellular solute-binding protein family 1 FIU26_11395 ENOG4105JXH GntR family transcriptional regulator FIU26_11400 ENOG4105DAA L-lactate FIU26_11405 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU26_11415 ENOG4108ZPC Polysaccharide pyruvyl transferase FIU26_11420 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FIU26_11425 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family FIU26_11430 ENOG4105D3Q Sugar transferase FIU26_11440 ENOG4105K64 Glycosyl transferase, family 2 FIU26_11450 ENOG4107QRS glycosyltransferase group 2 family protein FIU26_11455 ENOG41068W6 Capsular polysaccharide biosynthesis protein FIU26_11460 ENOG4108KMV Glycosyl transferase (Group 1 FIU26_11465 ENOG4105K64 Glycosyl transferase, family 2 FIU26_11470 ENOG4108PQP glycosyl transferase group 1 FIU26_11480 ENOG4108QV3 biosynthesis protein FIU26_11485 ENOG4105HTX biosynthesis protein FIU26_11495 ENOG4105EBR Carboxylesterase FIU26_11505 ENOG4105PY6 Phenolic acid decarboxylase FIU26_11510 ENOG4105NI3 Protein of unknown function (DUF3237) FIU26_11520 ENOG4105FQP Beta-lactamase FIU26_11525 ENOG4105EDQ levansucrase EC 2.4.1.10 FIU26_11530 ENOG4108HKT sucrose-6-phosphate hydrolase FIU26_11535 ENOG4107QTZ amino acid FIU26_11565 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FIU26_11570 ENOG4108URH decarboxylase FIU26_11575 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain FIU26_11580 ENOG4105CHH sulfate transporter FIU26_11585 ENOG4108V2W Carbonate dehydratase FIU26_11590 ENOG4105C5I Dehydrogenase FIU26_11600 ENOG4105C19 ABC transporter FIU26_11605 ENOG4105EWM Histidine kinase FIU26_11615 ENOG4107A6P FIU26_11620 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FIU26_11625 ENOG4105KRI phosphocarrier protein (HPr FIU26_11630 ENOG4105CIE May be required for sporulation (By similarity) FIU26_11635 ENOG4105CHW UPF0052 protein FIU26_11640 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) FIU26_11645 ENOG4108Z4K mutator MutT protein FIU26_11650 ENOG4105C3M thioredoxin reductase FIU26_11665 ENOG4105BZ1 (ABC) transporter FIU26_11675 ENOG4106FGC FIU26_11685 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FIU26_11690 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) FIU26_11695 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase FIU26_11700 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FIU26_11705 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FIU26_11710 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FIU26_11715 ENOG4107RN8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) FIU26_11720 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) FIU26_11730 ENOG4108E16 pectate lyase FIU26_11735 ENOG4108S4C acetyltransferase FIU26_11740 ENOG4107XGZ Hydrolase FIU26_11745 ENOG4105HKU nucleoside recognition domain-containing protein FIU26_11750 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) FIU26_11755 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) FIU26_11760 ENOG4105CE4 GlcNAc 6-P deacetylase FIU26_11765 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) FIU26_11770 ENOG4105FDP GntR family transcriptional regulator FIU26_11775 ENOG41088CQ domain protein FIU26_11785 ENOG4106A3M Cytochrome p-450 FIU26_11790 ENOG410625E FIU26_11805 ENOG41086DT Membrane protein of unknown function FIU26_11810 ENOG41067S9 phage shock protein C, PspC FIU26_11815 ENOG4108PY7 FIU26_11830 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FIU26_11835 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FIU26_11855 ENOG4105MKU Transcriptional regulator FIU26_11875 ENOG4105CN1 protease FIU26_11880 ENOG4105CRP Part of the ABC transporter FtsEX involved in FIU26_11885 ENOG4105CAK Cell division ATP-binding protein ftsE FIU26_11910 ENOG4105MS2 ribosomal subunit Interface protein FIU26_11925 ENOG4105MQ3 flagellar protein FliS FIU26_11930 ENOG4107RT6 flagellar hook-associated FIU26_11935 ENOG41083S7 flagellar protein FlaG FIU26_11940 ENOG4105I03 Flagellin FIU26_11945 ENOG41085Y9 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FIU26_11950 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) FIU26_11955 ENOG4105MKD FIU26_11960 ENOG4105DTJ flagellar hook-associated protein FIU26_11965 ENOG4105E1Q flagellar hook-associated protein FIU26_11980 ENOG4105RU3 FIU26_11985 ENOG41081UC Inherit from COG: Competence protein FIU26_12005 ENOG4105WH1 Two component transcriptional regulator luxr family FIU26_12010 ENOG4105BZU Histidine kinase FIU26_12015 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FIU26_12020 ENOG4108KGH TRANSCRIPTIONal FIU26_12025 ENOG4105ESV Glycosyl transferase, family 4 FIU26_12030 ENOG4107EF8 Glycosyl transferase (Group 1 FIU26_12045 ENOG4105QZI O-Antigen Polymerase FIU26_12050 ENOG4105C6Y Udp-glucose 6-dehydrogenase FIU26_12055 ENOG4107RA4 Glycosyl transferase (Group 1 FIU26_12060 ENOG4105PSV Polysaccharide Biosynthesis Protein FIU26_12065 ENOG4105D3Q Sugar transferase FIU26_12075 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FIU26_12080 ENOG4105JFG SpoIID LytB domain protein FIU26_12095 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FIU26_12115 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FIU26_12120 ENOG4105EY8 ABC transporter FIU26_12140 ENOG4107VDP teichoic acid biosynthesis FIU26_12145 ENOG41088M2 Glycosyl transferase family 2 FIU26_12195 ENOG4105DG6 mannose-6-phosphate isomerase FIU26_12210 ENOG4108NHD germination protein FIU26_12215 ENOG4105C54 Major Facilitator superfamily FIU26_12220 ENOG4108KGH TRANSCRIPTIONal FIU26_12225 ENOG4105J7I hydrolase FIU26_12230 ENOG4105K4H Nlp p60 protein FIU26_12240 ENOG4105PNM synthesis protein FIU26_12250 ENOG4105N98 Capsule biosynthesis protein capB FIU26_12255 ENOG4105ETE Transcriptional regulator (LacI family FIU26_12260 ENOG4108RVA ribokinase FIU26_12265 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) FIU26_12270 ENOG4105C2J ABC transporter FIU26_12275 ENOG4105CNN ABC, transporter FIU26_12280 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FIU26_12295 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FIU26_12300 ENOG4107FQX Alpha-acetolactate decarboxylase FIU26_12310 ENOG4107RSM transcriptional regulator FIU26_12325 ENOG4107XC4 flavin reductase domain protein, FMN-binding FIU26_12335 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FIU26_12345 ENOG4105CAH Chromate FIU26_12350 ENOG4105FGV Chromate FIU26_12360 ENOG4108WS4 fmn reductase FIU26_12365 ENOG4107V2S Transcriptional regulator FIU26_12375 ENOG410874W AraC family transcriptional regulator FIU26_12380 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) FIU26_12425 ENOG4105C6Y Udp-glucose 6-dehydrogenase FIU26_12430 ENOG4108RB3 Capsular polysaccharide biosynthesis protein FIU26_12435 ENOG4107YJ4 chain length determinant protein FIU26_12440 ENOG4105HTX biosynthesis protein FIU26_12450 ENOG4105KBK Zinc finger, swim domain protein FIU26_12455 ENOG4105C0D helicase FIU26_12460 ENOG410667J hydrolase FIU26_12465 ENOG4105E98 transcriptional regulator DeoR family FIU26_12470 ENOG4105Z8H single-stranded DNA-binding protein FIU26_12495 ENOG4108VAC response regulator FIU26_12505 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) FIU26_12510 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) FIU26_12520 ENOG4105CGA flagellar basal-body rod protein FlgG FIU26_12530 ENOG4105DFF Rod shape-determining protein mreb FIU26_12535 ENOG4105MT0 Sporulation transcriptional regulator spoiiid FIU26_12545 ENOG4107MII Sugar-specific transcriptional regulator TrmB FIU26_12550 ENOG4105CZM Major Facilitator FIU26_12555 ENOG4108M26 parallel beta-helix repeat protein FIU26_12560 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FIU26_12565 ENOG41080V3 Major Facilitator superfamily FIU26_12570 ENOG4105D3W isochorismatase FIU26_12575 ENOG4107P26 FIU26_12580 ENOG4105BZU Histidine kinase FIU26_12590 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FIU26_12600 ENOG4105FRN stage II sporulation protein FIU26_12605 ENOG4107TCE N-acetyltransferase FIU26_12625 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FIU26_12630 ENOG4107TXC Transcriptional regulator FIU26_12635 ENOG4106BRK FIU26_12640 ENOG4108RYK Nad-dependent epimerase dehydratase FIU26_12645 ENOG4108Z40 Transcriptional regulator FIU26_12650 ENOG4105CQM Urea amidohydrolase subunit alpha FIU26_12655 ENOG4105KI2 Urea amidohydrolase subunit beta FIU26_12660 ENOG4108YZ9 Urea amidohydrolase subunit gamma FIU26_12665 ENOG4108IV0 ABC, transporter FIU26_12670 ENOG4105C0Z ABC transporter FIU26_12680 ENOG4105C32 Amino acid ABC transporter (Permease) FIU26_12685 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein FIU26_12710 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FIU26_12720 ENOG4108TF4 von Willebrand factor, type A FIU26_12730 ENOG4105JFG SpoIID LytB domain protein FIU26_12735 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FIU26_12745 ENOG4106778 Protein of unknown function (DUF1146) FIU26_12760 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FIU26_12765 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) FIU26_12770 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) FIU26_12775 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) FIU26_12795 ENOG4107RB6 it plays a direct role in the translocation of protons across the membrane (By similarity) FIU26_12805 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) FIU26_12810 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FIU26_12815 ENOG4108UIC UPF0340 protein FIU26_12820 ENOG4108YZG isomerase FIU26_12825 ENOG4107WAU Protein tyrosine phosphatase FIU26_12830 ENOG410815N Probably functions as a manganese efflux pump (By similarity) FIU26_12835 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FIU26_12845 ENOG4108ZXQ stage ii sporulation protein r FIU26_12860 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FIU26_12865 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) FIU26_12870 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FIU26_12880 ENOG4107TT2 Auxin Efflux Carrier FIU26_12885 ENOG4105C6K Malic enzyme FIU26_12890 ENOG4107104 thymidine kinase FIU26_12895 ENOG41082DI 50s ribosomal protein l31 FIU26_12900 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FIU26_12910 ENOG4105CBT Fructose-1,6-bisphosphatase FIU26_12915 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FIU26_12920 ENOG4107XMI Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway FIU26_12925 ENOG4105D2N Aldolase FIU26_12930 ENOG410812K response regulator receiver protein FIU26_12940 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) FIU26_12950 ENOG4105C1G acyl-Coa dehydrogenase FIU26_12955 ENOG4105DF6 Fe-S oxidoreductase FIU26_12965 ENOG4105E5J UV damage endonuclease FIU26_12975 ENOG4105NAE bifunctional deaminase-reductase domain protein FIU26_12980 ENOG4105BZ1 (ABC) transporter FIU26_12985 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FIU26_13000 ENOG4105R3A Nitrate reductase FIU26_13005 ENOG4108IUE nitrate reductase beta subunit FIU26_13025 ENOG4107V6Q Cyclic nucleotide-binding domain FIU26_13035 ENOG4105C75 arginyL-tRNA synthetase FIU26_13040 ENOG410684U Domain of unknown function (DUF1934) FIU26_13050 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E FIU26_13095 ENOG4107JM4 Tetratricopeptide repeat FIU26_13105 ENOG4105CYW agmatinase FIU26_13110 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) FIU26_13115 ENOG4105BZ4 penicillin-binding protein FIU26_13125 ENOG4108XFG YwhD family FIU26_13130 ENOG4108Z4T Peptidase M50 FIU26_13135 ENOG41069HH 4-oxalocrotonate tautomerase FIU26_13140 ENOG41067TZ transcriptional regulator, MarR family FIU26_13145 ENOG4105C22 threonyL-tRNA synthetase FIU26_13160 ENOG4105DCI Phosphohydrolase FIU26_13170 ENOG4108VCI transcription factor, rsfa family FIU26_13175 ENOG4108RNG Permease of the drug metabolite transporter FIU26_13180 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) FIU26_13185 ENOG4105DUM transcriptional regulator, lysR family FIU26_13190 ENOG4108IJ2 phosphate acetyltransferase FIU26_13205 ENOG4105CHM Aminotransferase FIU26_13215 ENOG4108V3M Inherit from COG: acetyl-CoA carboxylase biotin carboxylase FIU26_13220 ENOG4105CHR reductase FIU26_13225 ENOG4106CHD Bacilysin biosynthesis protein bacB FIU26_13230 ENOG41061WN bacilysin biosynthesis protein FIU26_13235 ENOG4105FCW Major Facilitator superfamily FIU26_13250 ENOG4105C26 Dehydrogenase FIU26_13255 ENOG4105D82 Glutamate dehydrogenase FIU26_13265 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase FIU26_13270 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FIU26_13275 ENOG4105C1B dTDP-glucose 4-6-dehydratase FIU26_13280 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FIU26_13285 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG FIU26_13290 ENOG4107TY6 Acylneuraminate cytidylyltransferase FIU26_13300 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD FIU26_13305 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FIU26_13345 ENOG4105C26 Dehydrogenase FIU26_13350 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) FIU26_13355 ENOG4108RJ9 Glycosyl transferase, family 2 FIU26_13375 ENOG4105DWF phosphomethylpyrimidine kinase FIU26_13390 ENOG4105C5Y PTS System FIU26_13395 ENOG4108QTI )-transporter FIU26_13410 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FIU26_13415 ENOG4105DEN Luciferase family FIU26_13420 ENOG4108DBC nitroreductase FIU26_13460 ENOG4107BMA Transglycosylase associated protein FIU26_13470 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) FIU26_13475 ENOG4105WH5 Teichoic acid glycosylation protein FIU26_13500 ENOG4107ZXU DSBA oxidoreductase FIU26_13505 ENOG4105DBE peroxidase FIU26_13510 ENOG410650H (LipO)protein FIU26_13515 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FIU26_13525 ENOG4105CMU LysR family (Transcriptional regulator FIU26_13530 ENOG4105VAW lrga family FIU26_13535 ENOG41067MG lrgb family FIU26_13540 ENOG4108RDQ ABC transporter FIU26_13565 ENOG41067MG lrgb family FIU26_13570 ENOG4105D8G Major Facilitator superfamily FIU26_13580 ENOG4105DR4 Methyltransferase FIU26_13590 ENOG4108YV3 Protein of unknown function (DUF2711) FIU26_13595 ENOG4105CK1 PTS System FIU26_13605 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin FIU26_13625 ENOG4105X1N Glycosyl transferase family 8 FIU26_13635 ENOG4105GVJ transcriptional regulator FIU26_13640 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FIU26_13645 ENOG4105IIU Aminopeptidase FIU26_13660 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FIU26_13670 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) FIU26_13675 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FIU26_13685 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FIU26_13690 ENOG4108VHC Short-chain dehydrogenase reductase Sdr FIU26_13695 ENOG4105CM2 brancheD-chain amino acid aminotransferase FIU26_13700 ENOG4105F8D glycoside hydrolase family 4 FIU26_13705 ENOG4105VCP PTS System FIU26_13710 ENOG4105CK1 PTS System FIU26_13715 ENOG4105VZJ PTS System FIU26_13720 ENOG4105EMD TRANSCRIPTIONal FIU26_13730 ENOG4108VX5 3-methyladenine DNA glycosylase FIU26_13735 ENOG4105CH6 catalase FIU26_13750 ENOG4105DA5 (ABC) transporter FIU26_13755 ENOG41069JR FIU26_13775 ENOG4105ETS cytosine purines uracil thiamine allantoin FIU26_13780 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FIU26_13785 ENOG4108JJ8 (ABC) transporter FIU26_13790 ENOG4108JJ9 ABC, transporter FIU26_13795 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FIU26_13800 ENOG4105C4M (Ubiquinol oxidase) subunit I FIU26_13805 ENOG4105D2K citrate carrier protein FIU26_13820 ENOG4107BJW polysaccharide deacetylase FIU26_13850 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FIU26_13860 ENOG4105CMR udp-glucose 4-epimerase FIU26_13870 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FIU26_13895 ENOG4105DTD Dehydrogenase FIU26_13900 ENOG4108IIH CoA-transferase subunit B FIU26_13905 ENOG4105D6N CoA-transferase, subunit a FIU26_13910 ENOG4105CY2 Citrate transporter FIU26_13915 ENOG4105DHI Methyltransferase FIU26_13935 ENOG4105CH6 catalase FIU26_13940 ENOG4105D4T Citrate transporter FIU26_13945 ENOG410900G Protein of unknown function (DUF421) FIU26_13955 ENOG4105CS2 ec 3.2.1.21 FIU26_13960 ENOG4105C5Y PTS System FIU26_13965 ENOG4105CID antiterminator FIU26_13975 ENOG4105DEU major facilitator superfamily FIU26_13980 ENOG4105C1J atp-dependent rna helicase FIU26_13985 ENOG4107TDE lipolytic protein G-D-S-L family FIU26_14110 ENOG4107TS3 membrane protein, TerC FIU26_14115 ENOG4107YZX Universal stress protein FIU26_14120 ENOG4105CS2 ec 3.2.1.21 FIU26_14125 ENOG4105C5Y PTS System FIU26_14160 ENOG4107EV6 Inherit from COG: YD repeat protein FIU26_14175 ENOG4106Z5D Glycoside Hydrolase Family 43 FIU26_14180 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FIU26_14190 ENOG4105C84 Histidine ammonia-lyase FIU26_14195 ENOG4105CGP Urocanate hydratase FIU26_14200 ENOG4105CI2 imidazolone-5-propionate hydrolase FIU26_14205 ENOG4107W25 arginase agmatinase formiminoglutamase FIU26_14215 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) FIU26_14220 ENOG4105D9N nucleoside FIU26_14230 ENOG4107RHR regulatoR FIU26_14235 ENOG4108TM9 integral membrane protein FIU26_14240 ENOG4105ENY Ethanolamine utilization protein eutH FIU26_14245 ENOG4108PGP mmge prpd family protein FIU26_14250 ENOG4105CH2 amidohydrolase FIU26_14260 ENOG4108HW4 amino acid AbC transporter FIU26_14265 ENOG4105EAB amino acid AbC transporter FIU26_14270 ENOG4108XSB acetyltransferase, (GNAT) family FIU26_14275 ENOG4105CPU Monooxygenase FIU26_14280 ENOG4107QHE Choloylglycine hydrolase FIU26_14285 ENOG410667J hydrolase FIU26_14315 ENOG4108V5C ABC transporter FIU26_14345 ENOG4105D2N Aldolase FIU26_14350 ENOG4107TRN Xylose isomerase domain protein TIM barrel FIU26_14355 ENOG4105F0H myo-inositol catabolism protein FIU26_14360 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FIU26_14370 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) FIU26_14375 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) FIU26_14380 ENOG4105D7K pfkb domain protein FIU26_14390 ENOG4105C26 Dehydrogenase FIU26_14400 ENOG4105CPC Aldo Keto reductase FIU26_14415 ENOG4107QNK )-transporter FIU26_14420 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FIU26_14430 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FIU26_14440 ENOG4105ST3 Transcriptional regulator FIU26_14445 ENOG4105C26 Dehydrogenase FIU26_14460 ENOG41085PJ rdd domain containing protein FIU26_14475 ENOG4105J7D transcriptional regulator FIU26_14480 ENOG4107JEE Short-chain dehydrogenase reductase Sdr FIU26_14485 ENOG41061AU MarR family Transcriptional regulator FIU26_14495 ENOG41067MG lrgb family FIU26_14510 ENOG4105BZW Glycerate kinase FIU26_14515 ENOG4105G3Z GntR family transcriptional regulator FIU26_14520 ENOG4105CMG Carbohydrate kinase FIU26_14525 ENOG4105C6Z Gluconate FIU26_14530 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FIU26_14535 ENOG4105D3R alkyl hydroperoxide reductase FIU26_14540 ENOG4108JU3 Alkyl hydroperoxide reductase FIU26_14550 ENOG4105CS2 ec 3.2.1.21 FIU26_14560 ENOG4108S3Y transcriptional regulator FIU26_14570 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 FIU26_14575 ENOG4105DVF Cytosine-specific methyltransferase FIU26_14600 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) FIU26_14625 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) FIU26_14630 ENOG4105WQG acetyltransferase FIU26_14635 ENOG410780I phosphoprotein phosphatase activity FIU26_14645 ENOG41066UZ arginase EC 3.5.3.1 FIU26_14650 ENOG4108IQI permease FIU26_14655 ENOG4105C8Y Acetylornithine aminotransferase FIU26_14660 ENOG4108JUB Transcriptional regulator FIU26_14670 ENOG4105C0H protease FIU26_14675 ENOG4105Q2H domain protein FIU26_14690 ENOG4105BZU Histidine kinase FIU26_14695 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FIU26_14720 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis FIU26_14725 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase FIU26_14730 ENOG4105CDU Replicative dna helicase FIU26_14750 ENOG4105DJ2 Major Facilitator Superfamily FIU26_14755 ENOG4105EDW glycosyl transferase, family 39 FIU26_14760 ENOG4105K9Q Binds to the 23S rRNA (By similarity) FIU26_14765 ENOG4105BZR domain protein FIU26_14770 ENOG4108XMW Membrane FIU26_14785 ENOG4105KVH Transcriptional regulator FIU26_14790 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase FIU26_14820 ENOG4105D94 Major Facilitator Superfamily FIU26_14825 ENOG4107RSM transcriptional regulator FIU26_14830 ENOG41082BV acetyltransferase FIU26_14835 ENOG41081I9 integral membrane protein FIU26_14850 ENOG41079CX FIU26_14855 ENOG4108U05 Transcriptional regulator FIU26_14860 ENOG41082BV acetyltransferase FIU26_14870 ENOG4105C7Z Conserved Protein FIU26_14875 ENOG4107FCW Abortive infection protein FIU26_14885 ENOG4108UW5 maltose o-acetyltransferase FIU26_14890 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase FIU26_14900 ENOG4105CGK Exodeoxyribonuclease III FIU26_14905 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FIU26_14910 ENOG4108UUM single-stranded DNA-binding protein FIU26_14915 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) FIU26_14920 ENOG4105C3G gtp-binding protein FIU26_14925 ENOG4108J2R molybdopterin oxidoreductase FIU26_14930 ENOG4105VDK protein, conserved in bacteria FIU26_14940 ENOG4108ZDA Sporulation protein YyaC FIU26_14945 ENOG4105FA0 parb-like partition protein FIU26_14950 ENOG4107QJE Chromosome Partitioning Protein FIU26_14965 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) FIU26_14970 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) FIU26_14975 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FIU26_14990 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) FIU26_15000 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) FIU26_15005 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FIU26_15010 ENOG410848D S4 domain protein YaaA FIU26_15025 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FIU26_15030 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FIU26_15065 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FIU26_15075 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) FIU26_15080 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) FIU26_15085 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) FIU26_15095 ENOG4105ZMH deoxynucleoside kinase FIU26_15105 ENOG4105VRS hydrolase family 18 FIU26_15110 ENOG4105GTG Isochorismatase FIU26_15115 ENOG4108Z6B deaminase FIU26_15125 ENOG4105C6E dna polymerase iii FIU26_15130 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) FIU26_15135 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FIU26_15145 ENOG41067KS pro-sigma K processing FIU26_15185 ENOG4105CDW Resistance protein FIU26_15190 ENOG4105CXN decarboxylase FIU26_15195 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) FIU26_15200 ENOG4105X0R protein from nitrogen regulatory protein P-II FIU26_15205 ENOG4105XVJ Protein of unknown function (DUF327) FIU26_15210 ENOG4105FA2 dna polymerase iii FIU26_15215 ENOG4105MA4 psp1 domain protein FIU26_15220 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) FIU26_15225 ENOG41060K3 Methyltransferase FIU26_15230 ENOG4105VC4 domain protein FIU26_15235 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FIU26_15240 ENOG4105KRN Transcriptional regulator, abrb family FIU26_15245 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FIU26_15250 ENOG4105F8V Hydrolase, tatD family FIU26_15255 ENOG41069ER domain protein FIU26_15265 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FIU26_15270 ENOG4105XFA sporulation peptidase YabG FIU26_15275 ENOG4105W42 Veg protein FIU26_15280 ENOG4105XEW small acid-soluble spore protein FIU26_15285 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) FIU26_15290 ENOG4105DFT pur operon repressor FIU26_15295 ENOG4105KME endoribonuclease L-psp FIU26_15300 ENOG4105K4W Could be involved in septation (By similarity) FIU26_15305 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) FIU26_15310 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FIU26_15315 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) FIU26_15320 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) FIU26_15330 ENOG4108JA2 transcriptioN-repair coupling factor FIU26_15335 ENOG4108M14 stage v sporulation protein t FIU26_15345 ENOG4108IY2 MazG family FIU26_15350 ENOG41082I2 s4 domain protein FIU26_15355 ENOG4105VYY sporulation protein yabp FIU26_15370 ENOG41060GV RNA binding s1 domain protein FIU26_15400 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FIU26_15405 ENOG4108UGV hypoxanthine phosphoribosyltransferase FIU26_15410 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FIU26_15420 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FIU26_15425 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase FIU26_15430 ENOG4105C6T cysteine synthase FIU26_15435 ENOG4105CRQ synthase (Component I) FIU26_15440 ENOG4105DDQ anthranilate synthase FIU26_15445 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 FIU26_15450 ENOG4105EEI dihydropteroate synthase FIU26_15455 ENOG4105KRF dihydroneopterin aldolase FIU26_15460 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FIU26_15470 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FIU26_15475 ENOG4105CRK lysyL-tRNA synthetase FIU26_15560 ENOG4108Z0C Uvrb UvrC protein FIU26_15565 ENOG41066A3 ATP guanido phosphotransferase FIU26_15575 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FIU26_15580 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) FIU26_15585 ENOG4105CTP PilT protein domain protein FIU26_15590 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) FIU26_15595 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FIU26_15600 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) FIU26_15605 ENOG4105D7W serine acetyltransferase FIU26_15610 ENOG4105C8N cysteinyl-tRNA synthetase FIU26_15615 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) FIU26_15620 ENOG4105C2N RNA methyltransferase TrmH family group 3 FIU26_15625 ENOG4105M0M Tetracycline resistance protein FIU26_15645 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FIU26_15650 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) FIU26_15660 ENOG4108VZM 50s ribosomal protein L10 FIU26_15665 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FIU26_15670 ENOG4107Y49 methyltransferase FIU26_15675 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FIU26_15680 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FIU26_15685 ENOG4105XPM ribosomal protein FIU26_15690 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) FIU26_15695 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) FIU26_15700 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FIU26_15705 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FIU26_15710 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FIU26_15715 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) FIU26_15720 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) FIU26_15725 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FIU26_15730 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FIU26_15735 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity FIU26_15740 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FIU26_15745 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FIU26_15750 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FIU26_15755 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FIU26_15760 ENOG41082SA 50s ribosomal protein l29 FIU26_15765 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FIU26_15770 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) FIU26_15780 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits FIU26_15790 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FIU26_15795 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) FIU26_15800 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FIU26_15805 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FIU26_15810 ENOG4105VPB 50S ribosomal protein L30 FIU26_15815 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FIU26_15820 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FIU26_15830 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FIU26_15840 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FIU26_15850 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FIU26_15855 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FIU26_15860 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FIU26_15865 ENOG4108ZT0 50S ribosomal protein l17 FIU26_15870 ENOG4108JJB ABC transporter FIU26_15875 ENOG4108JJB ABC transporter FIU26_15880 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FIU26_15885 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FIU26_15890 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) FIU26_15895 ENOG4108UJD 30S ribosomal protein S9 FIU26_15905 ENOG4108I0C methyltransferase FIU26_15920 ENOG4105D1F ATP-binding protein FIU26_15935 ENOG4108NMV polysaccharide deacetylase FIU26_16020 ENOG4105CHH sulfate transporter FIU26_16030 ENOG4108SA1 esterase FIU26_16050 ENOG410874W AraC family transcriptional regulator FIU26_16055 ENOG4105EHZ conserved protein UCP016719 FIU26_16060 ENOG4105D17 glycoside hydrolase, family 3 domain protein FIU26_16080 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FIU26_16090 ENOG4105EWC Purine nucleoside phosphorylase FIU26_16120 ENOG4105EMN RNA polymerase sigma factor FIU26_16130 ENOG4105C8B TIGR00159 family FIU26_16135 ENOG4107U5W ybbr family FIU26_16140 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) FIU26_16155 ENOG4108TWJ NADH dehydrogenase subunit 5 FIU26_16175 ENOG4105GPN Uncharacterized conserved protein (DUF2294) FIU26_16215 ENOG4105E5W Transporter FIU26_16225 ENOG4105DTI Phosphonopyruvate decarboxylase FIU26_16275 ENOG4105G0J serine threonine protein kinase FIU26_16285 ENOG4106K80 FIU26_16295 ENOG4106DDH Sporulation-specific SASP protein FIU26_16305 ENOG4108HWY Beta-lactamase FIU26_16310 ENOG4107E6A Cytochrome p-450 FIU26_16325 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FIU26_16330 ENOG4105CXY transporter FIU26_16345 ENOG410645S MarR family Transcriptional regulator FIU26_16350 ENOG4105DCM major facilitator superfamily FIU26_16365 ENOG410631K Membrane FIU26_16370 ENOG4106AXJ AraC family transcriptional regulator FIU26_16375 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR FIU26_16380 ENOG4108TCS Glutamyl endopeptidase FIU26_16390 ENOG4108WC5 Alpha Beta Hydrolase Fold protein FIU26_16395 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FIU26_16400 ENOG4107ZTW SNARE associated Golgi FIU26_16420 ENOG4105C72 UPF0176 protein FIU26_16435 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) FIU26_16440 ENOG4108X79 transcriptional regulator FIU26_16455 ENOG4105CM2 brancheD-chain amino acid aminotransferase FIU26_16460 ENOG4108IQI permease FIU26_16465 ENOG4108J5H Homocysteine s-methyltransferase FIU26_16480 ENOG4105CSV Glutaminase FIU26_16495 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase FIU26_16500 ENOG4105C26 Dehydrogenase FIU26_16505 ENOG4105DJB Major Facilitator Superfamily FIU26_16510 ENOG4105EQX glucarate dehydratase FIU26_16515 ENOG41073TP transcriptional regulator FIU26_16520 ENOG4105CTX dehydratase FIU26_16535 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FIU26_16570 ENOG4105MUA Resistance protein FIU26_16580 ENOG4105DGI Alkaline phosphatase FIU26_16585 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FIU26_16590 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FIU26_16595 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) FIU26_16600 ENOG4107EPV Aminotransferase class V FIU26_16605 ENOG4105C0R drug resistance transporter emrb qaca subfamily FIU26_16610 ENOG4105J7D transcriptional regulator FIU26_16615 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold FIU26_16625 ENOG41060AI SEC-C motif FIU26_16640 ENOG4107SET aldo keto reductase FIU26_16690 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FIU26_16700 ENOG4105DSE periplasmic solute binding protein FIU26_16705 ENOG4105DIK (ABC) transporter FIU26_16715 ENOG4105DEN Luciferase family FIU26_16720 ENOG4108N0M stress protein FIU26_16725 ENOG4106FN3 tellurium resistance protein FIU26_16730 ENOG4106FN3 tellurium resistance protein FIU26_16735 ENOG4107TS3 membrane protein, TerC FIU26_16740 ENOG4108TTB tellurium resistance protein FIU26_16750 ENOG41079KZ Major Facilitator Superfamily FIU26_16755 ENOG4107XZQ multidrug resistance protein FIU26_16760 ENOG4108A65 Transcriptional regulator FIU26_16765 ENOG4108IJ7 Glycine betaine FIU26_16770 ENOG4107SQ8 Glycine betaine FIU26_16800 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FIU26_16835 ENOG4105EIG urea carboxylase-associated protein 1 FIU26_16840 ENOG4107RA1 nh(3)-dependent nad( ) synthetase FIU26_16845 ENOG4105I1F Resistance protein FIU26_16850 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) FIU26_16855 ENOG41089UC methyltransferase, type 11 FIU26_16860 ENOG4105C5Q Transcriptional regulator FIU26_16865 ENOG4105I82 acetyl xylan esterase FIU26_16870 ENOG410756H nucleotidyltransferase FIU26_16880 ENOG4105C26 Dehydrogenase FIU26_16885 ENOG4105CK7 Sodium proline symporter FIU26_16890 ENOG4107YHD transcriptional regulator FIU26_16900 ENOG4108PJD permease FIU26_16905 ENOG4105U6C Alpha beta hydrolase fold protein FIU26_16915 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FIU26_16920 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FIU26_16925 ENOG4108IFG nitrite reductase, (NAD(P)H) FIU26_16930 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) FIU26_16950 ENOG4105S7A ErfK ybiS ycfS ynhG family protein FIU26_16950 ENOG4105S7A ErfK ybiS ycfS ynhG family protein FIU26_16960 ENOG4105CKI cobalamin synthesis protein FIU26_16965 ENOG4105E5Q amino acid AbC transporter FIU26_16970 ENOG4107XKZ Amino acid ABC superfamily ATP binding cassette transporter binding protein FIU26_16975 ENOG4105HHM rdd domain containing protein FIU26_16985 ENOG4105K56 Transcriptional regulator FIU26_16995 ENOG4108VEN abc transporter atp-binding protein FIU26_17000 ENOG4105CS2 ec 3.2.1.21 FIU26_17015 ENOG4105C8Q Methyl-accepting chemotaxis FIU26_17020 ENOG41080HJ 6-phospho 3-hexuloisomerase FIU26_17025 ENOG4108VA3 3-hexulose-6-phosphate synthase FIU26_17030 ENOG4105KVH Transcriptional regulator FIU26_17035 ENOG4105CEY Amp-dependent synthetase and ligase FIU26_17065 ENOG4105SX7 Transporter FIU26_17075 ENOG4105W8Z 4'-phosphopantetheinyl transferase FIU26_17085 ENOG4105CDA abc transporter atp-binding protein FIU26_17090 ENOG4105DRP amino acid AbC transporter FIU26_17100 ENOG4106P55 Transcriptional regulator FIU26_17105 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FIU26_17110 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FIU26_17115 ENOG41069ZX FIU26_17120 ENOG41069ZX FIU26_17130 ENOG4105DUX Transporter FIU26_17145 ENOG4105E1K spore germination protein FIU26_17165 ENOG4107WD8 ABC transporter, permease FIU26_17170 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FIU26_17175 ENOG4105BZU Histidine kinase FIU26_17195 ENOG4105CFH Aspartokinase FIU26_17200 ENOG4105DHS permease protein FIU26_17205 ENOG4105CM4 permease protein FIU26_17210 ENOG4108IPW abc transporter atp-binding protein FIU26_17225 ENOG4105R8C Transcriptional regulator FIU26_17230 ENOG4108DBC nitroreductase FIU26_17235 ENOG41067V3 Antibiotic biosynthesis monooxygenase FIU26_17240 ENOG4105YVS arsR family transcriptional regulator FIU26_17250 ENOG4108JPW Aminotransferase FIU26_17255 ENOG4105C26 Dehydrogenase FIU26_17265 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FIU26_17270 ENOG4105KTB nuclear export factor GLE1 FIU26_17275 ENOG4108T5E Copper resistance protein FIU26_17280 ENOG4108ZYE Transcriptional regulator FIU26_17305 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FIU26_17310 ENOG4108ZX0 Signal peptidase I FIU26_17335 ENOG4105E7W lamb ycsf family protein FIU26_17340 ENOG4105C5A transporter FIU26_17345 ENOG4105CFM UPF0317 protein FIU26_17350 ENOG4105P4J Allophanate hydrolase, subunit 1 FIU26_17360 ENOG4107258 Transcriptional regulator FIU26_17365 ENOG4105XJB lipolytic protein G-D-S-L family FIU26_17375 ENOG41061CK Antibiotic biosynthesis monooxygenase FIU26_17380 ENOG4107RVG penicillin-binding protein FIU26_17385 ENOG4107QM2 Aldo Keto reductase FIU26_17390 ENOG4105ETD TRANSCRIPTIONal FIU26_17400 ENOG4105HMZ Methyltransferase FIU26_17405 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FIU26_17420 ENOG410606W general stress protein FIU26_17430 ENOG4105VCH membrane FIU26_17440 ENOG4105C9U ATP-dependent DNA helicase RecQ FIU26_17455 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) FIU26_17460 ENOG4107R8N Glycosyl transferase, family 2 FIU26_17470 ENOG4105C0X amino acid FIU26_17490 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) FIU26_17495 ENOG4107BMA Transglycosylase associated protein FIU26_17500 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) FIU26_17505 ENOG4105EU9 FIU26_17510 ENOG4105QVS general stress protein FIU26_17530 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FIU26_17535 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FIU26_17540 ENOG4108MRH transcriptional regulatory protein FIU26_17545 ENOG4107QJT sodium dicarboxylate symporter FIU26_17550 ENOG4106F5Q Membrane FIU26_17560 ENOG4105CJ1 ABC, transporter FIU26_17595 ENOG4105SZ6 Thioredoxin FIU26_17600 ENOG4105CPF Cell wall formation (By similarity) FIU26_17605 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FIU26_17615 ENOG4105C1J atp-dependent rna helicase FIU26_17620 ENOG410905X membrane-flanked domain protein FIU26_17625 ENOG4105CKV Membrane FIU26_17635 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) FIU26_17640 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein FIU26_17645 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FIU26_17655 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FIU26_17660 ENOG4107MMM Anti-sigma-factor antagonist FIU26_17665 ENOG4105FUA antagonist FIU26_17670 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase FIU26_17675 ENOG4107SGM protein serine threonine phosphatase FIU26_17680 ENOG4105WN5 stage II sporulation protein FIU26_17685 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) FIU26_17695 ENOG41064BQ Phosphatase FIU26_17755 ENOG4105VUF Transcriptional regulator FIU26_17760 ENOG4105E1F short-chain dehydrogenase reductase FIU26_17765 ENOG4107SET aldo keto reductase FIU26_17770 ENOG4105EMU Dehydrogenase FIU26_17775 ENOG4105DTD Dehydrogenase FIU26_17785 ENOG4105EMU Dehydrogenase FIU26_17790 ENOG4105ECK Fatty Acid Desaturase FIU26_17800 ENOG4105VEQ Cold shock protein FIU26_17805 ENOG4108VJ1 Transcriptional regulator (CarD family FIU26_17815 ENOG4108IMY Transcriptional regulator FIU26_17820 ENOG41086D8 Transcriptional regulator FIU26_17830 ENOG4105CZ9 Domain of unknown function (DU1801) FIU26_17835 ENOG4105GIG FIU26_17845 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein FIU26_17855 ENOG4105T38 integral membrane protein FIU26_17860 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FIU26_17865 ENOG4108ZMQ domain protein FIU26_17870 ENOG4105MJ9 esterase FIU26_17875 ENOG4107Z6X Transcriptional regulator FIU26_17890 ENOG41082YX Transcriptional regulator, arsr family FIU26_17895 ENOG4107R5R arsenical pump membrane protein FIU26_17900 ENOG4108UXE Protein tyrosine phosphatase FIU26_17905 ENOG4105Z7P Acetyltransferase (GNAT) family FIU26_17910 ENOG4107Y9U Membrane FIU26_17920 ENOG4108SQ9 flavin reductase domain protein, FMN-binding FIU26_17925 ENOG4108ZHR arsR family transcriptional regulator FIU26_17930 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FIU26_17945 ENOG4105ENE Histidine kinase FIU26_17950 ENOG4108VB1 regulatoR FIU26_17955 ENOG4105EYF MMPL domain protein FIU26_17980 ENOG4108UQV Membrane FIU26_17985 ENOG4108Z5V transcriptional regulator, merr family FIU26_17990 ENOG41076HS cation diffusion facilitator family transporter FIU26_17995 ENOG4108TVJ Nitroreductase FIU26_18000 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase FIU26_18005 ENOG4108VGI doxx family FIU26_18010 ENOG4105XXY Thioredoxin FIU26_18015 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FIU26_18030 ENOG4108VQJ O-methyltransferase FIU26_18035 ENOG410900G Protein of unknown function (DUF421) FIU26_18055 ENOG4105PF9 Transcriptional regulator FIU26_18065 ENOG4105WQG acetyltransferase FIU26_18075 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FIU26_18080 ENOG4105ETE Transcriptional regulator (LacI family FIU26_18090 ENOG4107TRE AP endonuclease, family 2 FIU26_18095 ENOG4105F27 Major Facilitator FIU26_18110 ENOG4105C85 amino acid FIU26_18120 ENOG41062A4 Transcriptional regulator FIU26_18125 ENOG4105EYF MMPL domain protein FIU26_18130 ENOG4108TVJ Nitroreductase FIU26_18135 ENOG4105FS7 Transcriptional regulator FIU26_18140 ENOG4108JCI Transcriptional regulator FIU26_18155 ENOG4105C2C drug resistance transporter, Bcr CflA FIU26_18165 ENOG4105DRR Transcriptional regulator, GntR family FIU26_18170 ENOG4105VRS hydrolase family 18 FIU26_18190 ENOG4105G6Z alkaline phosphatase FIU26_18205 ENOG4107TVP HD domain protein FIU26_18210 ENOG41090UD (LipO)protein FIU26_18215 ENOG4105F27 Major Facilitator FIU26_18220 ENOG4105VZJ PTS System FIU26_18225 ENOG4105VCP PTS System FIU26_18230 ENOG4105CK1 PTS System FIU26_18235 ENOG4105CS2 ec 3.2.1.21 FIU26_18240 ENOG4108TZY GntR Family Transcriptional Regulator FIU26_18245 ENOG4105EVU fructokinase FIU26_18250 ENOG4105DG6 mannose-6-phosphate isomerase FIU26_18255 ENOG4105D3P Mannan endo-1,4-beta-mannosidase FIU26_18300 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FIU26_18305 ENOG4105K8N protein family UPF0079, ATPase FIU26_18310 ENOG41072GX Peptidase M22 Glycoprotease FIU26_18315 ENOG410801F ribosomal-protein-alanine acetyltransferase FIU26_18320 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FIU26_18325 ENOG4105C5H ABC transporter FIU26_18330 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FIU26_18335 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) FIU26_18340 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FIU26_18345 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FIU26_18355 ENOG4108TYN CAAX amino terminal protease family protein FIU26_18360 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) FIU26_18365 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) FIU26_18380 ENOG4105PGZ NB-ARC domain FIU26_18385 ENOG4105CPQ Dehydrogenase FIU26_18390 ENOG4105CT4 transporter FIU26_18400 ENOG41087YS Phage shock protein A FIU26_18405 ENOG4105DQX Zinc finger domain FIU26_18410 ENOG4108WV1 Pfam:DUF477 FIU26_18420 ENOG4108ZMR Ion transport 2 domain-containing protein FIU26_18425 ENOG4107QNK )-transporter FIU26_18460 ENOG4107YUH hydrolase FIU26_18470 ENOG4107STQ Multicopper oxidase FIU26_18475 ENOG4105C85 amino acid FIU26_18490 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FIU26_18510 ENOG4105C7N Xanthine uracil vitamin C permease FIU26_18535 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FIU26_18540 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FIU26_18545 ENOG4105C83 adenylosuccinate lyase FIU26_18550 ENOG4105C8V SAICAR synthetase FIU26_18555 ENOG4105VR9 phosphoribosylformylglycinamidine synthase FIU26_18560 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I FIU26_18565 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii FIU26_18575 ENOG4105CXB phosphoribosylaminoimidazole synthetase FIU26_18580 ENOG4108V3E phosphoribosylglycinamide formyltransferase FIU26_18585 ENOG4105DC1 bifunctional purine biosynthesis protein purh FIU26_18590 ENOG4105C12 Phosphoribosylglycinamide synthetase FIU26_18600 ENOG4105DVH amino acid FIU26_18615 ENOG4108R5T secreted protein FIU26_18620 ENOG4105KGF protein, YerC YecD FIU26_18625 ENOG4105CBC glutamate synthase FIU26_18630 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) FIU26_18635 ENOG4105C4R Atp-dependent dna helicase FIU26_18640 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FIU26_18650 ENOG4105CRN Aminoglycoside phosphotransferase FIU26_18655 ENOG4105KT7 mgtC SapB transporter FIU26_18660 ENOG4105CK7 Sodium proline symporter FIU26_18665 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FIU26_18670 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FIU26_18675 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FIU26_18680 ENOG4108IG5 Transcriptional regulator FIU26_18690 ENOG4105CBD Diacylglycerol kinase FIU26_18695 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FIU26_18700 ENOG4105CVR type I restriction-modification system FIU26_18705 ENOG41082EK Restriction modification system DNA (Specificity FIU26_18710 ENOG4105DZR Type I site-specific deoxyribonuclease FIU26_18750 ENOG4105CDY transcriptional regulatory protein FIU26_18760 ENOG4105M4P Tetr family transcriptional regulator FIU26_18765 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein FIU26_18770 ENOG4107S9F NmrA family FIU26_18775 ENOG4105KHM amidohydrolase 2 FIU26_18780 ENOG4105ST3 Transcriptional regulator FIU26_18795 ENOG4105WEF catalase FIU26_18800 ENOG4105M18 -acetyltransferase FIU26_18815 ENOG4105C2F Histidine kinase FIU26_18820 ENOG4105EQD regulatoR FIU26_18825 ENOG410769Z extracellular solute-binding protein family 1 FIU26_18830 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FIU26_18835 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component FIU26_18840 ENOG4105F5H Glycosyl Hydrolase Family 88 FIU26_18845 ENOG41075H3 AraC family transcriptional regulator FIU26_18850 ENOG4107TDE lipolytic protein G-D-S-L family FIU26_18865 ENOG4105CX8 fg-gap repeat protein FIU26_18870 ENOG4105CX8 fg-gap repeat protein FIU26_18875 ENOG4107TDE lipolytic protein G-D-S-L family FIU26_18885 ENOG4105EKC FIU26_18890 ENOG4105E0S extracellular solute-binding protein family 1 FIU26_18900 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FIU26_18905 ENOG4105F8D glycoside hydrolase family 4 FIU26_18910 ENOG4105H67 Protein of unknown function (DUF421) FIU26_18915 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) FIU26_18920 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FIU26_18940 ENOG4106I4J membrane FIU26_18945 ENOG41082F9 transcriptional regulator FIU26_18950 ENOG41061H0 Monooxygenase FIU26_18955 ENOG4108R1P FIU26_18960 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FIU26_18965 ENOG4105E0M Sulfatase FIU26_18970 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase FIU26_18980 ENOG41090R9 glycosyltransferase FIU26_18985 ENOG4107R51 Glycosyl transferase, family 2 FIU26_18990 ENOG41090R9 glycosyltransferase FIU26_18995 ENOG4105EU0 Major facilitator Superfamily FIU26_19005 ENOG4105CUB amino acid FIU26_19010 ENOG4105C26 Dehydrogenase FIU26_19015 ENOG4105FKZ Methyl-accepting chemotaxis FIU26_19020 ENOG4105C5H ABC transporter FIU26_19030 ENOG4107SWG transcriptional regulator MERR family FIU26_19035 ENOG4105DXB Major Facilitator superfamily FIU26_19045 ENOG4105C5H ABC transporter FIU26_19050 ENOG4105FDU atp-dependent rna helicase FIU26_19060 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FIU26_19065 ENOG4105E0A ABC, transporter FIU26_19070 ENOG4108U1V ABC transporter, permease FIU26_19075 ENOG4105DQ5 transport system permease protein FIU26_19080 ENOG4108HUF Transporter FIU26_19095 ENOG4108J20 pectate lyase FIU26_19100 ENOG4107QPK )-transporter FIU26_19110 ENOG4108MRH transcriptional regulatory protein FIU26_19135 ENOG410855V Acylphosphatase FIU26_19140 ENOG4108RPX mosc domain containing protein FIU26_19160 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) FIU26_19190 ENOG4105GEU Spore germination protein FIU26_19200 ENOG4108Q5U germination protein, ger(x)c family FIU26_19205 ENOG4105E1K spore germination protein FIU26_19210 ENOG4105C5Y PTS System FIU26_19215 ENOG4105CG3 alpha amylase, catalytic region FIU26_19220 ENOG4107414 GntR family transcriptional regulator FIU26_19225 ENOG4108RCM Nitroreductase FIU26_19230 ENOG4105CGH 5'-nucleotidase FIU26_19235 ENOG4107RKG DJ-1/PfpI family FIU26_19250 ENOG4105KJF protein tyrosine phosphatase FIU26_19260 ENOG4107U9T Pfam:Ribonuclease_BN FIU26_19265 ENOG4108ISG Major Facilitator FIU26_19270 ENOG4105UPD Calcium Proton FIU26_19280 ENOG4105D8X mechanosensitive ion channel FIU26_19300 ENOG4106KE4 Dehydrogenase FIU26_19305 ENOG4105D7N magnesium and cobalt transport protein CorA FIU26_19320 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FIU26_19330 ENOG4105KNA -acetyltransferase FIU26_19345 ENOG4107RUY (E1 component), alpha subunit FIU26_19355 ENOG4107QKR Dehydrogenase FIU26_19365 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FIU26_19370 ENOG41069DP small acid-soluble spore protein FIU26_19375 ENOG4105KK4 UPF0060 membrane protein FIU26_19400 ENOG4105F8D glycoside hydrolase family 4 FIU26_19405 ENOG4108Q3X Transcriptional regulator FIU26_19410 ENOG4105CI1 PTS System FIU26_19415 ENOG4105BZ1 (ABC) transporter FIU26_19420 ENOG4105BZ1 (ABC) transporter FIU26_19430 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FIU26_19435 ENOG4105BZU Histidine kinase FIU26_19440 ENOG4105WH1 Two component transcriptional regulator luxr family FIU26_19445 ENOG4105CJ1 ABC, transporter FIU26_19450 ENOG41090VJ ABC-2 type transporter FIU26_19455 ENOG4108KYE ABC-2 type transporter FIU26_19465 ENOG4105U3E Transcriptional regulator FIU26_19470 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold FIU26_19475 ENOG4105H93 Acyltransferase family FIU26_19480 ENOG4108YYS metal-dependent hydrolase (By similarity) FIU26_19485 ENOG4105C0R drug resistance transporter emrb qaca subfamily FIU26_19490 ENOG410834F Transcriptional regulator FIU26_19500 ENOG4108MES Periplasmic binding protein FIU26_19505 ENOG4105DQ5 transport system permease protein FIU26_19510 ENOG4108IHU transport system permease protein FIU26_19520 ENOG4107Y03 Nitroreductase FIU26_19535 ENOG4105ECP epimerase FIU26_19555 ENOG4105F27 Major Facilitator FIU26_19575 ENOG4106AKJ FIU26_19580 ENOG4105D74 hydrolase FIU26_19585 ENOG4105CKK Glycosyl transferase, family 2 FIU26_19590 ENOG4105EJV Membrane FIU26_19595 ENOG41067AE Membrane-bound metal-dependent hydrolase FIU26_19600 ENOG4105CEN a g-specific adenine glycosylase FIU26_19605 ENOG4106BXE FIU26_19610 ENOG4105CAN Short-chain dehydrogenase reductase Sdr FIU26_19625 ENOG4105EVI UPF0374 protein FIU26_19630 ENOG4105BZ1 (ABC) transporter FIU26_19635 ENOG4107NBY Membrane FIU26_19645 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FIU26_19650 ENOG4105G5W regulator Fur family FIU26_19760 ENOG4108N23 SpoOM-related protein FIU26_19775 ENOG4105EC3 peptidase S51, dipeptidase E FIU26_19780 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) FIU26_19795 ENOG4105E2Y ABC, transporter FIU26_19800 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein FIU26_19805 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FIU26_19810 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FIU26_19820 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) FIU26_19825 ENOG4107D63 FIU26_19830 ENOG4105VZ8 Transcriptional regulator FIU26_19845 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FIU26_19855 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FIU26_19875 ENOG4105CYN Serine protein kinase FIU26_19880 ENOG4106AKX UPF0229 protein FIU26_19885 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FIU26_19890 ENOG4105CW7 secretion protein, HlyD family FIU26_19895 ENOG4105C0R drug resistance transporter emrb qaca subfamily FIU26_19900 ENOG4105CS1 NAD(P)H quinone oxidoreductase FIU26_19915 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FIU26_19920 ENOG4105CZV ABC transporter FIU26_19925 ENOG4105CJ1 ABC, transporter FIU26_19935 ENOG4105VEQ Cold shock protein FIU26_19950 ENOG4105BZU Histidine kinase FIU26_19990 ENOG4108YBP pseudouridine synthase FIU26_20000 ENOG41080XP Cbs domain FIU26_20005 ENOG4107YBY Hydrolase FIU26_20010 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FIU26_20020 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FIU26_20025 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FIU26_20035 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FIU26_20040 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FIU26_20050 ENOG4105BZU Histidine kinase FIU26_20055 ENOG4105WH1 Two component transcriptional regulator luxr family FIU26_20090 ENOG4105ED1 spovr family FIU26_20095 ENOG4105G6Z alkaline phosphatase FIU26_20110 ENOG4105BZN citrate synthase FIU26_20115 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FIU26_20120 ENOG4105CUB amino acid FIU26_20125 ENOG4105C8J )-transporter FIU26_20130 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FIU26_20145 ENOG4105J37 FIU26_20150 ENOG4108AEY RNA polymerase sigma factor FIU26_20155 ENOG4108FN7 Aldo keto reductase FIU26_20160 ENOG4105F6E Acyl-transferase FIU26_20165 ENOG4107VFR oxidoreductase FIU26_20175 ENOG4105C37 (CBS) domain FIU26_20185 ENOG4105CHM Aminotransferase FIU26_20190 ENOG4105C37 (CBS) domain FIU26_20200 ENOG4105WMR Protein CrcB homolog FIU26_20205 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FIU26_20215 ENOG4105D64 Mechanosensitive ion channel FIU26_20220 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FIU26_20225 ENOG4107VMI polysaccharide deacetylase FIU26_20230 ENOG4105F0I Aminotransferase FIU26_20250 ENOG4105BZ1 (ABC) transporter FIU26_20255 ENOG4105BZ1 (ABC) transporter FIU26_20285 ENOG410839P FIU26_20295 ENOG4106MP8 UPF0754 membrane protein FIU26_20300 ENOG4105WZB UPF0342 protein FIU26_20305 ENOG4105F1N DNA alkylation repair FIU26_20315 ENOG4105D4P Coproporphyrinogen iii oxidase FIU26_20320 ENOG4107S91 Sodium hydrogen exchanger FIU26_20325 ENOG4105NCW Trka-c domain protein FIU26_20335 ENOG4105CGU Enoyl-CoA hydratase FIU26_20345 ENOG4108IUX (ABC) transporter FIU26_20350 ENOG4105RHA ABC transporter, permease FIU26_20355 ENOG4107VRP DNA repair exonuclease FIU26_20360 ENOG4106D4I domain protein FIU26_20365 ENOG4105EQI Metal Dependent Phosphohydrolase FIU26_20375 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FIU26_20420 ENOG4105NBU tryptophan transport protein FIU26_20425 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) FIU26_20430 ENOG4105K59 histidine triad (HIT) protein FIU26_20465 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation FIU26_20470 ENOG4105BZ4 penicillin-binding protein FIU26_20475 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) FIU26_20480 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FIU26_20485 ENOG4105C1Q protoporphyrinogen oxidase FIU26_20495 ENOG4105ECB domain protein FIU26_20505 ENOG41090T1 Membrane FIU26_20515 ENOG4105DER m42 family FIU26_20530 ENOG4106AXD FIU26_20535 ENOG4108RQ5 Beta-lactamase domain-containing protein FIU26_20540 ENOG4105DF9 Lipoate-protein, ligase FIU26_20550 ENOG4105CEY Amp-dependent synthetase and ligase FIU26_20560 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 FIU26_20570 ENOG4105KD7 acetyltransferase FIU26_20580 ENOG4108HUF Transporter FIU26_20585 ENOG4107TB6 phosphoglycerate mutase FIU26_20595 ENOG4107F3J Amp-dependent synthetase and ligase FIU26_20600 ENOG4107ZYJ bioY protein FIU26_20605 ENOG4106YBV Methyl-accepting chemotaxis FIU26_20625 ENOG4105XVF Competence transcription factor FIU26_20630 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FIU26_20635 ENOG4105X3H Excalibur domain protein FIU26_20640 ENOG4105E1V na solute symporter FIU26_20645 ENOG4106CAD Protein of unknown function (DUF3311) FIU26_20650 ENOG41060YP FIU26_20665 ENOG4107SCK Monooxygenase FIU26_20670 ENOG4108INS Transcriptional regulator FIU26_20690 ENOG4105TRI Hydrolase FIU26_20705 ENOG4108KK1 membrane protein AbrB duplication FIU26_20710 ENOG4106K7D Major facilitator family transporter FIU26_20715 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FIU26_20720 ENOG4105VWP Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding FIU26_20735 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FIU26_20745 ENOG4105EYH Exonuclease FIU26_20795 ENOG4105ERH Fumarylacetoacetate hydrolase