locus-tag	class	description
N1207_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N1207_00010	COG0592	DNA-directed DNA polymerase activity
N1207_00015	COG2501	S4 domain
N1207_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N1207_00030	COG0187	DNA topoisomerase II activity
N1207_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N1207_00070	COG0516	GMP reductase activity
N1207_00070	COG0517	IMP dehydrogenase activity
N1207_00075	COG1686	Belongs to the peptidase S11 family
N1207_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
N1207_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
N1207_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N1207_00100	COG1428	Deoxynucleoside kinase
N1207_00105	COG1428	Deoxynucleoside kinase
N1207_00110	COG1388	LysM domain
N1207_00110	COG3858	chitin binding
N1207_00115	COG1335	isochorismatase
N1207_00120	COG0590	tRNA wobble adenosine to inosine editing
N1207_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N1207_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N1207_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N1207_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
N1207_00190	COG3853	Toxic anion resistance protein (TelA)
N1207_00195	COG1982	Orn Lys Arg decarboxylase major
N1207_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N1207_00205	COG3870	Protein conserved in bacteria
N1207_00210	COG1728	Protein conserved in bacteria
N1207_00215	COG0470	DNA polymerase III
N1207_00220	COG1774	PSP1 C-terminal conserved region
N1207_00225	COG4467	Involved in initiation control of chromosome replication
N1207_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N1207_00235	COG2827	Endonuclease containing a URI domain
N1207_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N1207_00245	COG2002	toxin-antitoxin pair type II binding
N1207_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N1207_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N1207_00255	COG0084	hydrolase, TatD family'
N1207_00260	COG3583	domain protein
N1207_00260	COG3584	3D domain protein
N1207_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N1207_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N1207_00280	COG4466	Protein conserved in bacteria
N1207_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N1207_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N1207_00300	COG0251	oxidation-reduction process
N1207_00305	COG2088	sporulation resulting in formation of a cellular spore
N1207_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N1207_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N1207_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N1207_00325	COG0193	aminoacyl-tRNA hydrolase activity
N1207_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N1207_00340	COG2002	toxin-antitoxin pair type II binding
N1207_00345	COG2244	polysaccharide biosynthetic process
N1207_00350	COG3956	TIGRFAM MazG family protein
N1207_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N1207_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N1207_00375	COG1098	S1 RNA binding domain
N1207_00390	COG2208	phosphoserine phosphatase activity
N1207_00395	COG2304	oxidoreductase activity
N1207_00400	COG0515	serine threonine protein kinase
N1207_00405	COG0037	tRNA processing
N1207_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
N1207_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N1207_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
N1207_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N1207_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N1207_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N1207_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N1207_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
N1207_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N1207_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N1207_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N1207_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N1207_00470	COG1396	sequence-specific DNA binding
N1207_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N1207_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N1207_00560	COG4463	regulation of RNA biosynthetic process
N1207_00565	COG3880	PFAM UvrB UvrC protein
N1207_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
N1207_00575	COG0542	response to heat
N1207_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N1207_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
N1207_00590	COG4956	integral membrane protein (PIN domain superfamily)
N1207_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N1207_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N1207_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N1207_00610	COG1045	serine acetyltransferase
N1207_00615	COG0215	cysteine-tRNA ligase activity
N1207_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
N1207_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N1207_00630	COG3688	RNA-binding protein containing a PIN domain
N1207_00635	COG1595	DNA-templated transcription, initiation
N1207_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N1207_00650	COG0250	Participates in transcription elongation, termination and antitermination
N1207_00660	COG0081	regulation of translation
N1207_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N1207_00675	COG2813	Specifically methylates the guanine in position
N1207_00680	COG0085	RNA polymerase activity
N1207_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N1207_00690	COG1358	cellular component organization or biogenesis
N1207_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N1207_00700	COG0049	tRNA binding
N1207_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N1207_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N1207_00715	COG0596	Alpha beta hydrolase
N1207_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N1207_00730	COG0088	Forms part of the polypeptide exit tunnel
N1207_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N1207_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N1207_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N1207_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N1207_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N1207_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N1207_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N1207_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N1207_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N1207_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N1207_00820	COG0200	Binds to the 23S rRNA
N1207_00825	COG0201	protein transport
N1207_00830	COG0563	adenylate kinase activity
N1207_00835	COG0024	Methionine aminopeptidase
N1207_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
N1207_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N1207_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N1207_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N1207_00865	COG0202	RNA polymerase activity
N1207_00870	COG0203	ribosomal protein L17
N1207_00875	COG1122	ATPase activity
N1207_00880	COG1122	ATPase activity
N1207_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N1207_00890	COG0101	tRNA pseudouridine synthase activity
N1207_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N1207_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N1207_00905	COG2226	methyltransferase
N1207_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
N1207_00920	COG0489	protein tyrosine kinase activity
N1207_00930	COG2194	sulfuric ester hydrolase activity
N1207_00935	COG0726	polysaccharide deacetylase
N1207_01020	COG0659	secondary active sulfate transmembrane transporter activity
N1207_01025	COG0385	Bile acid
N1207_01030	COG2819	hydrolase of the alpha beta superfamily
N1207_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N1207_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N1207_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N1207_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N1207_01050	COG2207	Transcriptional regulator
N1207_01055	COG3876	Protein conserved in bacteria
N1207_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
N1207_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N1207_01070	COG1263	PTS System
N1207_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_01075	COG1737	Transcriptional regulator
N1207_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N1207_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N1207_01090	COG1683	Conserved Protein
N1207_01120	COG1595	DNA-templated transcription, initiation
N1207_01125	COG5662	AntiSigma factor
N1207_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N1207_01135	COG4856	YbbR-like protein
N1207_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N1207_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N1207_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N1207_01160	COG2169	Transcriptional regulator
N1207_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N1207_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N1207_01175	COG3002	Belongs to the UPF0753 family
N1207_01180	COG0288	reversible hydration of carbon dioxide
N1207_01190	COG5609	conserved protein (DUF2294)
N1207_01195	COG0640	Transcriptional regulator
N1207_01200	COG2814	Major facilitator Superfamily
N1207_01215	COG0515	serine threonine protein kinase
N1207_01230	COG1113	amino acid transport
N1207_01245	COG2602	Beta-lactamase
N1207_01250	COG2124	cytochrome p450
N1207_01260	COG0531	amino acid
N1207_01265	COG0584	glycerophosphoryl diester phosphodiesterase
N1207_01270	COG2271	Major facilitator Superfamily
N1207_01280	COG0456	acetyltransferase
N1207_01280	COG1846	Transcriptional regulator
N1207_01285	COG2271	Major facilitator Superfamily
N1207_01295	COG3409	Peptidoglycan-binding domain 1 protein
N1207_01300	COG0697	spore germination
N1207_01305	COG1917	Cupin 2, conserved barrel domain protein
N1207_01305	COG2207	Transcriptional regulator
N1207_01310	COG1397	ADP-ribosylglycohydrolase
N1207_01315	COG5444	nuclease activity
N1207_01320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
N1207_01325	COG3591	Belongs to the peptidase S1B family
N1207_01335	COG0596	Alpha beta hydrolase
N1207_01340	COG1183	phosphatidylcholine synthase activity
N1207_01345	COG0586	Pfam SNARE associated Golgi protein
N1207_01350	COG0688	phosphatidylethanolamine metabolic process
N1207_01360	COG2312	Erythromycin esterase
N1207_01365	COG1054	Belongs to the UPF0176 family
N1207_01370	COG1301	dicarboxylic acid transport
N1207_01375	COG2190	(PTS) system
N1207_01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_01375	COG1263	PTS System
N1207_01380	COG0363	glucosamine-6-phosphate deaminase activity
N1207_01385	COG2188	Transcriptional regulator
N1207_01395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N1207_01400	COG0833	amino acid
N1207_01405	COG2040	homocysteine
N1207_01410	COG1115	amino acid carrier protein
N1207_01415	COG2066	Belongs to the glutaminase family
N1207_01420	COG4191	Histidine kinase
N1207_01425	COG0784	Response regulator, receiver
N1207_01430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N1207_01435	COG1012	belongs to the aldehyde dehydrogenase family
N1207_01440	COG2271	Major facilitator Superfamily
N1207_01445	COG4948	Mandelate Racemase Muconate Lactonizing
N1207_01450	COG2186	Transcriptional regulator
N1207_01455	COG2721	sulfolactate sulfo-lyase activity
N1207_01460	COG3173	Aminoglycoside phosphotransferase
N1207_01470	COG0697	spore germination
N1207_01475	COG0745	RESPONSE REGULATOR receiver
N1207_01480	COG2205	protein histidine kinase activity
N1207_01485	COG1131	(ABC) transporter
N1207_01505	COG3773	Cell wall hydrolase
N1207_01510	COG2304	oxidoreductase activity
N1207_01520	COG3540	Alkaline phosphatase
N1207_01525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N1207_01530	COG0805	protein transport
N1207_01535	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
N1207_01540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N1207_01545	COG0477	Major facilitator Superfamily
N1207_01550	COG1309	transcriptional regulator
N1207_01555	COG0252	asparaginase activity
N1207_01560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N1207_01565	COG1714	RDD family
N1207_01570	COG3012	SEC-C Motif Domain Protein
N1207_01570	COG1405	negative regulation of cell septum assembly
N1207_01575	COG3290	protein histidine kinase activity
N1207_01580	COG3279	Response regulator of the LytR AlgR family
N1207_01585	COG4555	ABC transporter
N1207_01590	COG1668	transmembrane transport
N1207_01595	COG0667	Aldo Keto reductase
N1207_01610	COG1595	DNA-templated transcription, initiation
N1207_01615	COG1595	DNA-templated transcription, initiation
N1207_01620	COG1876	peptidase activity
N1207_01625	COG0457	Tetratricopeptide repeat
N1207_01630	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_01635	COG0366	Alpha amylase catalytic
N1207_01640	COG0803	Belongs to the bacterial solute-binding protein 9 family
N1207_01645	COG1121	(ABC) transporter
N1207_01650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N1207_01655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N1207_01660	COG2310	stress, protein
N1207_01665	COG2310	stress, protein
N1207_01670	COG2310	stress, protein
N1207_01675	COG0861	Integral membrane protein TerC family
N1207_01685	COG3853	Toxic anion resistance protein (TelA)
N1207_01690	COG0477	Major facilitator Superfamily
N1207_01695	COG2814	Major facilitator Superfamily
N1207_01700	COG0640	Transcriptional regulator
N1207_01705	COG4175	Glycine betaine
N1207_01705	COG0517	IMP dehydrogenase activity
N1207_01710	COG4176	ABC-type proline glycine betaine transport system permease component
N1207_01715	COG2113	Glycine betaine
N1207_01720	COG1473	amidohydrolase
N1207_01725	COG1288	antiporter activity
N1207_01735	COG0366	Alpha amylase catalytic
N1207_01740	COG0039	L-malate dehydrogenase activity
N1207_01745	COG1620	l-lactate permease
N1207_01750	COG2814	Major facilitator Superfamily
N1207_01755	COG1846	Transcriptional regulator
N1207_01760	COG1280	lysine exporter protein (LysE YggA)
N1207_01765	COG3403	YqcI/YcgG family
N1207_01770	COG1113	amino acid transport
N1207_01775	COG3665	Urea carboxylase-associated protein
N1207_01780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N1207_01785	COG1660	Displays ATPase and GTPase activities
N1207_01790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N1207_01795	COG2226	methyltransferase
N1207_01800	COG0583	DNA-binding transcription factor activity
N1207_01805	COG3458	cephalosporin-C deacetylase activity
N1207_01810	COG3541	Predicted nucleotidyltransferase
N1207_01815	COG0506	proline dehydrogenase activity
N1207_01820	COG1012	belongs to the aldehyde dehydrogenase family
N1207_01825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N1207_01830	COG2508	Transcriptional regulator
N1207_01835	COG3689	TIGRFAM TIGR03943 family protein
N1207_01840	COG0701	Predicted permease
N1207_01845	COG2267	carboxylic ester hydrolase activity
N1207_01850	COG0492	ferredoxin-NADP+ reductase activity
N1207_01855	COG1587	Uroporphyrinogen-III synthase
N1207_01855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N1207_01860	COG2146	nitrite reductase [NAD(P)H] activity
N1207_01865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N1207_01870	COG0243	molybdopterin cofactor binding
N1207_01875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N1207_01880	COG2223	nitrite transmembrane transporter activity
N1207_01885	COG1469	GTP cyclohydrolase I activity
N1207_01890	COG1376	ErfK ybiS ycfS ynhG family protein
N1207_01900	COG0523	cobalamin synthesis protein
N1207_01905	COG0765	amino acid transport
N1207_01910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N1207_01920	COG1714	RDD family
N1207_01930	COG2723	6-phospho-beta-galactosidase activity
N1207_01940	COG3209	COG3209 Rhs family protein
N1207_01945	COG0840	transmembrane signaling receptor activity
N1207_01945	COG3290	protein histidine kinase activity
N1207_01950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N1207_01955	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
N1207_01960	COG1733	regulation of RNA biosynthetic process
N1207_01965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_01995	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N1207_02000	COG2814	Major facilitator Superfamily
N1207_02010	COG0697	spore germination
N1207_02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N1207_02025	COG2364	Membrane
N1207_02030	COG1126	abc transporter atp-binding protein
N1207_02035	COG0765	amino acid transport
N1207_02040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N1207_02045	COG0583	DNA-binding transcription factor activity
N1207_02050	COG0163	prenyltransferase activity
N1207_02055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N1207_02070	COG0596	Alpha beta hydrolase
N1207_02075	COG3104	oligopeptide transport
N1207_02080	COG5434	Belongs to the glycosyl hydrolase 28 family
N1207_02090	COG0697	spore germination
N1207_02100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N1207_02105	COG1136	(ABC) transporter
N1207_02110	COG0577	efflux transmembrane transporter activity
N1207_02115	COG0745	RESPONSE REGULATOR receiver
N1207_02120	COG5002	protein histidine kinase activity
N1207_02120	COG3850	Histidine kinase
N1207_02125	COG0457	Tetratricopeptide repeat
N1207_02145	COG0527	aspartate kinase activity
N1207_02150	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N1207_02155	COG4605	iron ion homeostasis
N1207_02160	COG4604	ABC transporter, ATP-binding protein
N1207_02165	COG4607	ABC-type enterochelin transport system periplasmic component
N1207_02170	COG2814	Major facilitator Superfamily
N1207_02175	COG1309	transcriptional regulator
N1207_02180	COG0778	Nitroreductase
N1207_02185	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N1207_02190	COG0640	Transcriptional regulator
N1207_02195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N1207_02200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N1207_02205	COG1012	belongs to the aldehyde dehydrogenase family
N1207_02210	COG4975	Glucose uptake
N1207_02215	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_02220	COG4549	nuclear export factor GLE1
N1207_02225	COG1276	copper resistance
N1207_02225	COG2372	response to copper ion
N1207_02230	COG1349	DNA-binding transcription factor activity
N1207_02240	COG2213	PTS system mannitol-specific
N1207_02245	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N1207_02250	COG0246	Mannitol dehydrogenase
N1207_02255	COG0473	3-isopropylmalate dehydrogenase activity
N1207_02260	COG0681	Belongs to the peptidase S26 family
N1207_02265	COG0412	Dienelactone hydrolase
N1207_02270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N1207_02280	COG0561	phosphatase activity
N1207_02285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
N1207_02290	COG1914	H( )-stimulated, divalent metal cation uptake system
N1207_02295	COG4336	lyase activity
N1207_02300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
N1207_02305	COG1984	allophanate hydrolase subunit 2
N1207_02310	COG1414	Transcriptional regulator
N1207_02315	COG2755	lipolytic protein G-D-S-L family
N1207_02325	COG2329	Antibiotic biosynthesis monooxygenase
N1207_02330	COG0768	penicillin binding
N1207_02335	COG4989	oxidoreductase activity
N1207_02340	COG3711	transcriptional antiterminator
N1207_02345	COG0318	PFAM AMP-dependent synthetase and ligase
N1207_02350	COG2226	methyltransferase
N1207_02355	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_02360	COG1917	Cupin 2, conserved barrel domain protein
N1207_02365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N1207_02370	COG3871	stress protein (general stress protein 26)
N1207_02380	COG2814	Major facilitator Superfamily
N1207_02385	COG1522	sequence-specific DNA binding
N1207_02390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N1207_02390	COG0551	DNA topoisomerase type I activity
N1207_02395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
N1207_02400	COG3706	GGDEF domain
N1207_02405	COG5298	Protein conserved in bacteria
N1207_02410	COG1215	transferase activity, transferring glycosyl groups
N1207_02420	COG0531	amino acid
N1207_02425	COG0494	nUDIX hydrolase
N1207_02430	COG0028	Belongs to the TPP enzyme family
N1207_02445	COG1914	H( )-stimulated, divalent metal cation uptake system
N1207_02450	COG2261	transglycosylase associated protein
N1207_02455	COG4876	unkown
N1207_02460	COG2217	Heavy metal translocating P-type atpase
N1207_02465	COG3729	General stress protein
N1207_02470	COG0662	Cupin 2, conserved barrel domain protein
N1207_02475	COG2329	Antibiotic biosynthesis monooxygenase
N1207_02480	COG3546	catalase activity
N1207_02485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N1207_02490	COG3290	protein histidine kinase activity
N1207_02495	COG4565	transcriptional regulatory protein
N1207_02500	COG1301	dicarboxylic acid transport
N1207_02505	COG0628	permease
N1207_02510	COG1131	(ABC) transporter
N1207_02515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N1207_02525	COG1960	acyl-CoA dehydrogenase activity
N1207_02540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N1207_02545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N1207_02550	COG1181	Belongs to the D-alanine--D-alanine ligase family
N1207_02555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N1207_02560	COG0513	Belongs to the DEAD box helicase family
N1207_02565	COG3402	PFAM membrane-flanked domain
N1207_02570	COG3428	Bacterial PH domain
N1207_02575	COG0705	Rhomboid family
N1207_02580	COG0736	holo-[acyl-carrier-protein] synthase activity
N1207_02585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N1207_02590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N1207_02595	COG0864	Transcriptional regulator
N1207_02600	COG2337	Toxic component of a toxin-antitoxin (TA) module
N1207_02605	COG1366	Belongs to the anti-sigma-factor antagonist family
N1207_02610	COG1366	Belongs to the anti-sigma-factor antagonist family
N1207_02615	COG2172	sigma factor antagonist activity
N1207_02620	COG2208	phosphoserine phosphatase activity
N1207_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
N1207_02630	COG2172	sigma factor antagonist activity
N1207_02635	COG1191	sigma factor activity
N1207_02640	COG2208	phosphoserine phosphatase activity
N1207_02645	COG2183	response to ionizing radiation
N1207_02655	COG3091	SprT-like family
N1207_02695	COG0582	viral genome integration into host DNA
N1207_02700	COG2856	Zn peptidase
N1207_02705	COG1396	sequence-specific DNA binding
N1207_02735	COG1674	ftsk spoiiie
N1207_02740	COG2946	Replication initiation factor
N1207_02775	COG0433	COG0433 Predicted ATPase
N1207_02785	COG5644	endopeptidase inhibitor activity
N1207_02790	COG0741	lytic transglycosylase activity
N1207_02790	COG0791	NLP P60 protein
N1207_02810	COG0457	Tetratricopeptide repeat
N1207_02815	COG0582	viral genome integration into host DNA
N1207_02830	COG0457	Tetratricopeptide repeat
N1207_02855	COG5444	nuclease activity
N1207_02865	COG1476	TRANSCRIPTIONal
N1207_02875	COG3239	Fatty acid desaturase
N1207_02880	COG1278	Cold shock
N1207_02885	COG1329	Transcriptional regulator
N1207_02890	COG0697	spore germination
N1207_02895	COG2207	Transcriptional regulator
N1207_02895	COG1917	Cupin 2, conserved barrel domain protein
N1207_02900	COG0697	spore germination
N1207_02905	COG3708	Transcriptional regulator
N1207_02905	COG2207	Transcriptional regulator
N1207_02910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N1207_02915	COG0477	Major facilitator Superfamily
N1207_02925	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
N1207_02940	COG1309	transcriptional regulator
N1207_02945	COG0697	spore germination
N1207_02950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N1207_02955	COG2030	dehydratase
N1207_02960	COG3545	Serine hydrolase
N1207_02965	COG1733	regulation of RNA biosynthetic process
N1207_02970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N1207_02975	COG1733	regulation of RNA biosynthetic process
N1207_02980	COG2249	NAD(P)H dehydrogenase (quinone) activity
N1207_02985	COG2814	Major facilitator Superfamily
N1207_02990	COG1309	transcriptional regulator
N1207_02995	COG0640	Transcriptional regulator
N1207_03000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N1207_03010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N1207_03015	COG0697	spore germination
N1207_03020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N1207_03025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N1207_03030	COG0640	Transcriptional regulator
N1207_03035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N1207_03050	COG4585	Histidine kinase
N1207_03055	COG2197	response regulator
N1207_03060	COG2409	Drug exporters of the RND superfamily
N1207_03065	COG0596	Alpha beta hydrolase
N1207_03070	COG1811	Na channel or pump
N1207_03075	COG0789	Transcriptional regulator
N1207_03075	COG4978	Transcriptional regulator
N1207_03080	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N1207_03085	COG0778	Nitroreductase
N1207_03090	COG0346	lactoylglutathione lyase activity
N1207_03095	COG2259	Doxx family
N1207_03100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N1207_03120	COG2323	membrane
N1207_03125	COG2323	membrane
N1207_03130	COG0071	Belongs to the small heat shock protein (HSP20) family
N1207_03145	COG1309	transcriptional regulator
N1207_03155	COG0456	acetyltransferase
N1207_03160	COG0488	(ABC) transporter
N1207_03165	COG1113	amino acid transport
N1207_03170	COG2318	DinB family
N1207_03175	COG1846	Transcriptional regulator
N1207_03180	COG1033	growth of symbiont in host cell
N1207_03180	COG2409	Drug exporters of the RND superfamily
N1207_03185	COG0778	Nitroreductase
N1207_03190	COG1846	Transcriptional regulator
N1207_03195	COG2814	Major facilitator Superfamily
N1207_03200	COG0730	response to heat
N1207_03205	COG1802	Transcriptional regulator
N1207_03210	COG1388	LysM domain
N1207_03210	COG3858	chitin binding
N1207_03215	COG1819	glycosyl
N1207_03225	COG1785	Belongs to the alkaline phosphatase family
N1207_03230	COG5646	InterPro IPR014922
N1207_03240	COG0454	-acetyltransferase
N1207_03245	COG1078	dGTPase activity
N1207_03250	COG1388	LysM domain
N1207_03255	COG2814	Major facilitator Superfamily
N1207_03260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N1207_03265	COG1447	Phosphotransferase system cellobiose-specific component IIA
N1207_03270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N1207_03275	COG2723	6-phospho-beta-galactosidase activity
N1207_03280	COG2188	Transcriptional regulator
N1207_03285	COG1940	carbohydrate kinase activity
N1207_03290	COG1482	cell wall glycoprotein biosynthetic process
N1207_03295	COG4124	Belongs to the glycosyl hydrolase 26 family
N1207_03340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N1207_03345	COG0802	atpase or kinase
N1207_03350	COG1214	PFAM Peptidase M22, glycoprotease
N1207_03355	COG0456	acetyltransferase
N1207_03360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N1207_03365	COG0488	(ABC) transporter
N1207_03370	COG0315	cyclic pyranopterin monophosphate synthase activity
N1207_03375	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
N1207_03380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N1207_03385	COG0805	protein transport
N1207_03395	COG1266	CAAX protease self-immunity
N1207_03405	COG0459	protein refolding
N1207_03410	COG1073	alpha beta
N1207_03415	COG0457	Tetratricopeptide repeat
N1207_03420	COG1063	alcohol dehydrogenase
N1207_03425	COG2211	Major facilitator Superfamily
N1207_03430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N1207_03435	COG1842	Phage shock protein A
N1207_03440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N1207_03445	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
N1207_03450	COG4260	virion core protein, lumpy skin disease virus
N1207_03460	COG2814	Major facilitator Superfamily
N1207_03465	COG1063	alcohol dehydrogenase
N1207_03470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N1207_03475	COG0823	Involved in the tonB-independent uptake of proteins
N1207_03490	COG2267	carboxylic ester hydrolase activity
N1207_03500	COG2132	Multicopper oxidase
N1207_03505	COG1113	amino acid transport
N1207_03515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N1207_03520	COG0714	Associated with various cellular activities
N1207_03525	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
N1207_03530	COG1305	Transglutaminase-like
N1207_03535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N1207_03535	COG0519	Catalyzes the synthesis of GMP from XMP
N1207_03550	COG2252	PERMEase
N1207_03555	COG3064	Membrane
N1207_03565	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
N1207_03575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N1207_03580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N1207_03585	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N1207_03590	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N1207_03595	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N1207_03600	COG0047	phosphoribosylformylglycinamidine synthase activity
N1207_03605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N1207_03610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N1207_03615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N1207_03620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N1207_03625	COG0138	bifunctional purine biosynthesis protein purh
N1207_03630	COG0151	Belongs to the GarS family
N1207_03635	COG1522	sequence-specific DNA binding
N1207_03640	COG0531	amino acid
N1207_03650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N1207_03655	COG1470	cell adhesion involved in biofilm formation
N1207_03660	COG4496	protein, YerC YecD
N1207_03665	COG0069	glutamate synthase activity
N1207_03670	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
N1207_03675	COG0210	DNA helicase
N1207_03680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N1207_03685	COG4851	CamS sex pheromone cAM373 precursor
N1207_03690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N1207_03695	COG1285	pathogenesis
N1207_03700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N1207_03705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N1207_03710	COG0154	amidase activity
N1207_03715	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N1207_03725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N1207_03730	COG1597	lipid kinase activity
N1207_03735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N1207_03750	COG5444	nuclease activity
N1207_03755	COG3391	amine dehydrogenase activity
N1207_03760	COG0457	Tetratricopeptide repeat
N1207_03770	COG0217	transcriptional regulatory protein
N1207_03780	COG1309	transcriptional regulator
N1207_03785	COG3631	Ketosteroid isomerase-related protein
N1207_03805	COG3546	catalase activity
N1207_03810	COG0454	-acetyltransferase
N1207_03820	COG5578	integral membrane protein
N1207_03825	COG2972	Histidine kinase
N1207_03830	COG4753	response regulator
N1207_03830	COG2207	Transcriptional regulator
N1207_03835	COG1653	transport
N1207_03840	COG1175	transmembrane transport
N1207_03845	COG0395	ABC-type sugar transport system, permease component
N1207_03850	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N1207_03855	COG2207	Transcriptional regulator
N1207_03860	COG2755	lipolytic protein G-D-S-L family
N1207_03870	COG5578	integral membrane protein
N1207_03875	COG3401	FG-GAP repeat protein
N1207_03880	COG3401	FG-GAP repeat protein
N1207_03885	COG2755	lipolytic protein G-D-S-L family
N1207_03890	COG1874	Beta-galactosidase
N1207_03900	COG1653	transport
N1207_03905	COG4209	transmembrane transport
N1207_03910	COG0395	ABC-type sugar transport system, permease component
N1207_03915	COG1486	melibiose metabolic process
N1207_03920	COG2323	membrane
N1207_03925	COG2329	Antibiotic biosynthesis monooxygenase
N1207_03930	COG0346	lactoylglutathione lyase activity
N1207_03945	COG5583	Uncharacterized small protein (DUF2292)
N1207_03950	COG0670	Belongs to the BI1 family
N1207_03955	COG0697	spore germination
N1207_03960	COG1846	Transcriptional regulator
N1207_03965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N1207_03985	COG1368	sulfuric ester hydrolase activity
N1207_03990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N1207_03995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N1207_04000	COG1442	glycosyl transferase family 8
N1207_04005	COG1216	Glycosyl transferase, family 2
N1207_04010	COG1442	glycosyl transferase family 8
N1207_04015	COG2223	nitrite transmembrane transporter activity
N1207_04020	COG1011	Hydrolase
N1207_04025	COG0531	amino acid
N1207_04030	COG1012	belongs to the aldehyde dehydrogenase family
N1207_04035	COG0840	transmembrane signaling receptor activity
N1207_04040	COG0488	(ABC) transporter
N1207_04050	COG0789	Transcriptional regulator
N1207_04055	COG2814	Major facilitator Superfamily
N1207_04060	COG1404	Belongs to the peptidase S8 family
N1207_04080	COG0488	(ABC) transporter
N1207_04085	COG0513	Belongs to the DEAD box helicase family
N1207_04090	COG0456	acetyltransferase
N1207_04095	COG2130	NADP-dependent
N1207_04100	COG1120	ATPase activity
N1207_04105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N1207_04110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N1207_04115	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
N1207_04130	COG3866	Pectate lyase
N1207_04135	COG0471	metal ion transport
N1207_04140	COG3290	protein histidine kinase activity
N1207_04145	COG4565	transcriptional regulatory protein
N1207_04150	COG3181	Tripartite tricarboxylate transporter family receptor
N1207_04160	COG2851	Citrate transporter
N1207_04165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N1207_04170	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
N1207_04175	COG1254	Belongs to the acylphosphatase family
N1207_04180	COG2258	MOSC domain
N1207_04200	COG0024	Methionine aminopeptidase
N1207_04205	COG1263	PTS System
N1207_04205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_04210	COG1368	sulfuric ester hydrolase activity
N1207_04225	COG1115	amino acid carrier protein
N1207_04230	COG0531	amino acid
N1207_04245	COG0697	spore germination
N1207_04250	COG1263	PTS System
N1207_04250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_04255	COG0366	Alpha amylase catalytic
N1207_04260	COG2188	Transcriptional regulator
N1207_04265	COG0778	Nitroreductase
N1207_04270	COG0737	Belongs to the 5'-nucleotidase family
N1207_04275	COG0693	protein deglycase activity
N1207_04280	COG2814	Major facilitator Superfamily
N1207_04285	COG4840	Belongs to the UPF0435 family
N1207_04290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N1207_04295	COG4980	gas vesicle protein
N1207_04300	COG1295	ribonuclease BN
N1207_04305	COG0477	Major facilitator Superfamily
N1207_04310	COG0387	Pfam Sodium calcium exchanger
N1207_04320	COG0668	transmembrane transport
N1207_04325	COG0535	radical SAM domain protein
N1207_04335	COG0726	polysaccharide deacetylase
N1207_04340	COG2084	Dehydrogenase
N1207_04345	COG0598	Magnesium transport protein CorA
N1207_04350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N1207_04355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N1207_04365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N1207_04370	COG4637	Psort location Cytoplasmic, score
N1207_04380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N1207_04385	COG0022	dehydrogenase e1 component
N1207_04390	COG0508	dehydrogenase complex catalyzes the overall conversion of
N1207_04395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N1207_04400	COG3284	Transcriptional regulator
N1207_04410	COG1742	UPF0060 membrane protein
N1207_04435	COG4842	Belongs to the WXG100 family
N1207_04440	COG1486	melibiose metabolic process
N1207_04445	COG1737	Transcriptional regulator
N1207_04450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_04450	COG1263	PTS System
N1207_04455	COG5434	Belongs to the glycosyl hydrolase 28 family
N1207_04460	COG1132	(ABC) transporter
N1207_04465	COG1132	(ABC) transporter
N1207_04470	COG2259	Doxx family
N1207_04475	COG2514	catechol 2,3-dioxygenase activity
N1207_04480	COG4585	Histidine kinase
N1207_04485	COG2197	response regulator
N1207_04490	COG1131	(ABC) transporter
N1207_04495	COG1511	domain protein
N1207_04495	COG0842	Transport permease protein
N1207_04500	COG0842	Transport permease protein
N1207_04505	COG1695	Transcriptional regulator
N1207_04510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N1207_04515	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
N1207_04520	COG2318	DinB family
N1207_04525	COG2814	Major facilitator Superfamily
N1207_04530	COG1846	Transcriptional regulator
N1207_04535	COG0392	lysyltransferase activity
N1207_04535	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N1207_04540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N1207_04545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N1207_04550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N1207_04555	COG0384	phenazine biosynthesis protein PhzF
N1207_04560	COG0778	Nitroreductase
N1207_04575	COG1090	epimerase
N1207_04580	COG2137	regulation of response to DNA damage stimulus
N1207_04590	COG2814	Major facilitator Superfamily
N1207_04605	COG3103	Sh3 type 3 domain protein
N1207_04610	COG5658	integral membrane protein
N1207_04615	COG0596	Alpha beta hydrolase
N1207_04620	COG0463	Glycosyl transferase, family 2
N1207_04625	COG4485	Bacterial membrane protein, YfhO
N1207_04630	COG1988	membrane-bound metal-dependent
N1207_04635	COG1194	a g-specific adenine glycosylase
N1207_04645	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_04660	COG3557	Belongs to the UPF0374 family
N1207_04665	COG1132	(ABC) transporter
N1207_04670	COG4129	membrane
N1207_04675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N1207_04680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N1207_04685	COG0735	belongs to the Fur family
N1207_04795	COG4326	sporulation control protein
N1207_04805	COG5577	PFAM Coat F domain
N1207_04815	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N1207_04830	COG0753	catalase activity
N1207_04835	COG1116	anion transmembrane transporter activity
N1207_04840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N1207_04845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N1207_04850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N1207_04860	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N1207_04870	COG1476	TRANSCRIPTIONal
N1207_04880	COG3382	B3 4 domain protein
N1207_04885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N1207_04895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N1207_04900	COG0789	Transcriptional regulator
N1207_04905	COG1664	Polymer-forming cytoskeletal
N1207_04910	COG1664	Polymer-forming cytoskeletal
N1207_04915	COG2766	serine protein kinase
N1207_04920	COG2718	Belongs to the UPF0229 family
N1207_04925	COG1846	Transcriptional regulator
N1207_04930	COG1566	PFAM secretion protein HlyD family protein
N1207_04935	COG2814	Major facilitator Superfamily
N1207_04940	COG0655	NAD(P)H dehydrogenase (quinone) activity
N1207_04960	COG1725	Transcriptional regulator
N1207_04965	COG1131	(ABC) transporter
N1207_04970	COG1131	(ABC) transporter
N1207_04975	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N1207_04980	COG1278	Cold shock
N1207_04985	COG1464	Belongs to the NlpA lipoprotein family
N1207_04990	COG3706	GGDEF domain
N1207_04995	COG1823	symporter activity
N1207_05025	COG5577	PFAM Coat F domain
N1207_05030	COG4085	toxin activity
N1207_05030	COG1525	nuclease
N1207_05030	COG0737	Belongs to the 5'-nucleotidase family
N1207_05035	COG3764	Sortase (surface protein transpeptidase)
N1207_05040	COG0564	pseudouridine synthase activity
N1207_05050	COG0517	IMP dehydrogenase activity
N1207_05055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N1207_05060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N1207_05060	COG3153	acetyltransferase
N1207_05065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N1207_05070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
N1207_05075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N1207_05080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N1207_05085	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N1207_05090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N1207_05095	COG4585	Histidine kinase
N1207_05095	COG2203	Gaf domain
N1207_05100	COG2197	response regulator
N1207_05105	COG0431	NADPH-dependent FMN reductase
N1207_05120	COG0791	NLP P60 protein
N1207_05120	COG1388	LysM domain
N1207_05125	COG1959	2 iron, 2 sulfur cluster binding
N1207_05130	COG0668	transmembrane transport
N1207_05135	COG2719	SpoVR family
N1207_05140	COG1785	Belongs to the alkaline phosphatase family
N1207_05145	COG0791	NLP P60 protein
N1207_05145	COG1388	LysM domain
N1207_05150	COG0583	DNA-binding transcription factor activity
N1207_05155	COG0372	Belongs to the citrate synthase family
N1207_05160	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_05165	COG0531	amino acid
N1207_05170	COG0733	neurotransmitter:sodium symporter activity
N1207_05175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N1207_05180	COG0456	acetyltransferase
N1207_05195	COG1595	DNA-templated transcription, initiation
N1207_05200	COG0667	Aldo Keto reductase
N1207_05205	COG0204	Acyl-transferase
N1207_05210	COG1253	flavin adenine dinucleotide binding
N1207_05215	COG0789	Transcriptional regulator
N1207_05220	COG0436	Aminotransferase
N1207_05225	COG1253	flavin adenine dinucleotide binding
N1207_05230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N1207_05235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N1207_05240	COG0584	glycerophosphoryl diester phosphodiesterase
N1207_05250	COG0668	transmembrane transport
N1207_05255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N1207_05260	COG0726	polysaccharide deacetylase
N1207_05265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N1207_05270	COG1757	Na H antiporter
N1207_05275	COG0589	response to stress
N1207_05285	COG1132	(ABC) transporter
N1207_05290	COG1132	(ABC) transporter
N1207_05295	COG0702	epimerase
N1207_05315	COG0189	ligase activity
N1207_05320	COG0189	ligase activity
N1207_05325	COG4399	Belongs to the UPF0754 family
N1207_05330	COG3679	Belongs to the UPF0342 family
N1207_05335	COG4335	DNA alkylation repair
N1207_05340	COG0561	phosphatase activity
N1207_05345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N1207_05350	COG0475	glutathione-regulated potassium exporter activity
N1207_05355	COG0490	domain, Protein
N1207_05365	COG1024	Enoyl-CoA hydratase
N1207_05375	COG4152	abc transporter atp-binding protein
N1207_05380	COG1668	transmembrane transport
N1207_05385	COG0420	3'-5' exonuclease activity
N1207_05390	COG4717	serine-type aminopeptidase activity
N1207_05395	COG3481	metal-dependent phosphohydrolase, HD sub domain
N1207_05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N1207_05435	COG1846	Transcriptional regulator
N1207_05440	COG4980	gas vesicle protein
N1207_05455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N1207_05460	COG0537	adenosine 5'-monophosphoramidase activity
N1207_05465	COG1131	(ABC) transporter
N1207_05470	COG4473	ABC transporter
N1207_05480	COG1473	amidohydrolase
N1207_05485	COG3069	C4-dicarboxylate transmembrane transporter activity
N1207_05495	COG2329	Antibiotic biosynthesis monooxygenase
N1207_05500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N1207_05505	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N1207_05510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N1207_05515	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
N1207_05520	COG1309	transcriptional regulator
N1207_05525	COG1511	domain protein
N1207_05530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N1207_05535	COG4377	Putative membrane peptidase family (DUF2324)
N1207_05545	COG1363	Peptidase, m42
N1207_05550	COG4405	Protein conserved in bacteria
N1207_05555	COG1301	dicarboxylic acid transport
N1207_05565	COG1234	tRNA 3'-trailer cleavage
N1207_05570	COG0095	Lipoate-protein ligase
N1207_05575	COG0702	epimerase
N1207_05580	COG0318	PFAM AMP-dependent synthetase and ligase
N1207_05590	COG0501	Belongs to the peptidase M48B family
N1207_05600	COG0456	acetyltransferase
N1207_05605	COG0604	alcohol dehydrogenase
N1207_05610	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
N1207_05615	COG0406	alpha-ribazole phosphatase activity
N1207_05620	COG0183	Belongs to the thiolase family
N1207_05625	COG0318	PFAM AMP-dependent synthetase and ligase
N1207_05630	COG1268	BioY protein
N1207_05635	COG0840	transmembrane signaling receptor activity
N1207_05640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N1207_05640	COG0723	plastoquinol--plastocyanin reductase activity
N1207_05645	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_05655	COG4903	ComK protein
N1207_05660	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_05670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N1207_05685	COG0398	Pfam SNARE associated Golgi protein
N1207_05690	COG0681	Belongs to the peptidase S26 family
N1207_05695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N1207_05700	COG1846	Transcriptional regulator
N1207_05710	COG0738	Major facilitator superfamily
N1207_05715	COG0673	inositol 2-dehydrogenase activity
N1207_05720	COG0561	phosphatase activity
N1207_05725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N1207_05730	COG1609	Transcriptional regulator
N1207_05735	COG3180	Ammonia monooxygenase
N1207_05740	COG2814	Major facilitator Superfamily
N1207_05740	COG0477	Major facilitator Superfamily
N1207_05745	COG4533	DNA binding
N1207_05755	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
N1207_05760	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
N1207_05765	COG1074	ATP-dependent DNA helicase activity
N1207_05770	COG0420	3'-5' exonuclease activity
N1207_05775	COG0419	ATPase involved in DNA repair
N1207_05780	COG1403	HNH endonuclease
N1207_05820	COG5337	Spore coat protein CotH
N1207_05825	COG0179	Fumarylacetoacetate (FAA) hydrolase
N1207_05835	COG1404	Belongs to the peptidase S8 family
N1207_05845	COG0367	asparagine synthase
N1207_05850	COG2318	DinB family
N1207_05860	COG0534	Mate efflux family protein
N1207_05865	COG1917	Cupin 2, conserved barrel domain protein
N1207_05865	COG2207	Transcriptional regulator
N1207_05870	COG1609	Transcriptional regulator
N1207_05875	COG0673	inositol 2-dehydrogenase activity
N1207_05880	COG2318	DinB family
N1207_05885	COG1279	arginine transmembrane transporter activity
N1207_05890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N1207_05895	COG1357	PFAM Pentapeptide repeats (8 copies)
N1207_05900	COG2267	carboxylic ester hydrolase activity
N1207_05905	COG0529	Catalyzes the synthesis of activated sulfate
N1207_05910	COG2046	Belongs to the sulfate adenylyltransferase family
N1207_05915	COG0175	sulfate reduction
N1207_05920	COG2045	Belongs to the ComB family
N1207_05925	COG1809	phosphosulfolactate synthase activity
N1207_05930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N1207_05935	COG4948	Mandelate Racemase Muconate Lactonizing
N1207_05940	COG2814	Major facilitator Superfamily
N1207_05945	COG0454	-acetyltransferase
N1207_05950	COG2153	protein acetylation
N1207_05955	COG0646	methionine synthase
N1207_05955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N1207_05960	COG1666	GTP binding
N1207_05985	COG1695	Transcriptional regulator
N1207_06000	COG3227	Zinc metalloprotease (Elastase)
N1207_06005	COG1307	EDD domain protein, DegV family
N1207_06010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N1207_06030	COG0561	phosphatase activity
N1207_06035	COG1073	alpha beta
N1207_06040	COG2151	metal-sulfur cluster biosynthetic enzyme
N1207_06050	COG0277	FAD linked oxidase domain protein
N1207_06055	COG2271	Major facilitator Superfamily
N1207_06060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N1207_06065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N1207_06075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N1207_06080	COG0505	Belongs to the CarA family
N1207_06085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N1207_06090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N1207_06105	COG2267	carboxylic ester hydrolase activity
N1207_06115	COG1744	ABC transporter substrate-binding protein PnrA-like
N1207_06130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N1207_06135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N1207_06140	COG5504	Zn-dependent protease
N1207_06145	COG0444	Belongs to the ABC transporter superfamily
N1207_06150	COG4608	Belongs to the ABC transporter superfamily
N1207_06160	COG0601	transmembrane transport
N1207_06165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N1207_06175	COG0180	Tryptophanyl-tRNA synthetase
N1207_06180	COG4166	transmembrane transport
N1207_06185	COG0601	transmembrane transport
N1207_06190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N1207_06195	COG0444	Belongs to the ABC transporter superfamily
N1207_06200	COG4608	Belongs to the ABC transporter superfamily
N1207_06205	COG2814	Major facilitator Superfamily
N1207_06210	COG0456	acetyltransferase
N1207_06215	COG1393	Belongs to the ArsC family
N1207_06220	COG0861	Integral membrane protein TerC family
N1207_06230	COG4862	establishment of competence for transformation
N1207_06240	COG4469	Competence protein
N1207_06245	COG1164	Oligoendopeptidase f
N1207_06255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N1207_06260	COG2346	COG2346, Truncated hemoglobins
N1207_06265	COG0741	lytic transglycosylase activity
N1207_06270	COG4116	CYTH
N1207_06280	COG2357	RelA SpoT domain protein
N1207_06285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N1207_06290	COG0564	pseudouridine synthase activity
N1207_06295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N1207_06300	COG0475	glutathione-regulated potassium exporter activity
N1207_06300	COG0569	domain protein
N1207_06305	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N1207_06310	COG0352	thiamine-phosphate diphosphorylase activity
N1207_06315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N1207_06320	COG2104	thiamine diphosphate biosynthetic process
N1207_06325	COG2022	thiamine diphosphate biosynthetic process
N1207_06330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N1207_06335	COG0351	phosphomethylpyrimidine kinase
N1207_06340	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N1207_06395	COG0210	DNA helicase
N1207_06405	COG2153	protein acetylation
N1207_06410	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N1207_06415	COG2382	esterase
N1207_06420	COG0626	cystathionine gamma-synthase activity
N1207_06425	COG0626	cystathionine gamma-synthase activity
N1207_06430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N1207_06435	COG5505	Protein of unknown function (DUF819)
N1207_06450	COG2856	Zn peptidase
N1207_06460	COG1525	nuclease
N1207_06465	COG1396	sequence-specific DNA binding
N1207_06480	COG3646	Phage regulatory protein
N1207_06480	COG3645	SOS response
N1207_06520	COG3935	DnaD domain protein
N1207_06525	COG1484	DNA-dependent DNA replication
N1207_06580	COG1595	DNA-templated transcription, initiation
N1207_06615	COG5484	DNA packaging
N1207_06685	COG3953	SLT domain
N1207_06685	COG5280	Phage tail tape measure protein TP901
N1207_06690	COG1388	LysM domain
N1207_06690	COG0791	NLP P60 protein
N1207_06750	COG1388	LysM domain
N1207_06750	COG3409	Peptidoglycan-binding domain 1 protein
N1207_06750	COG5632	N-Acetylmuramoyl-L-alanine amidase
N1207_06760	COG5444	nuclease activity
N1207_06785	COG5444	nuclease activity
N1207_06835	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N1207_06840	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_06850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N1207_06850	COG3711	transcriptional antiterminator
N1207_06855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N1207_06855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N1207_06855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N1207_06860	COG1482	cell wall glycoprotein biosynthetic process
N1207_06870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N1207_06880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N1207_06895	COG0109	protoheme IX farnesyltransferase activity
N1207_06905	COG0726	polysaccharide deacetylase
N1207_06920	COG5504	Zn-dependent protease
N1207_06925	COG2205	protein histidine kinase activity
N1207_06935	COG3383	formate dehydrogenase (NAD+) activity
N1207_06940	COG2427	Protein of unknown function (DUF1641)
N1207_06950	COG1051	belongs to the nudix hydrolase family
N1207_06960	COG2124	cytochrome p450
N1207_06965	COG1819	glycosyl
N1207_06985	COG1587	Uroporphyrinogen-III synthase
N1207_06990	COG0390	transport system, permease component
N1207_06995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N1207_07000	COG0697	spore germination
N1207_07005	COG4297	protein containing double-stranded beta helix domain
N1207_07015	COG1252	NADH dehydrogenase
N1207_07020	COG1904	glucuronate isomerase
N1207_07025	COG2211	Major facilitator Superfamily
N1207_07030	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N1207_07035	COG1063	alcohol dehydrogenase
N1207_07040	COG1312	Catalyzes the dehydration of D-mannonate
N1207_07045	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_07050	COG2271	Major facilitator Superfamily
N1207_07055	COG1609	Transcriptional regulator
N1207_07060	COG0246	Mannitol dehydrogenase
N1207_07065	COG2721	sulfolactate sulfo-lyase activity
N1207_07070	COG0730	response to heat
N1207_07075	COG2318	DinB family
N1207_07080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N1207_07085	COG0457	Tetratricopeptide repeat
N1207_07095	COG2350	Protein conserved in bacteria
N1207_07100	COG3409	Peptidoglycan-binding domain 1 protein
N1207_07100	COG5632	N-Acetylmuramoyl-L-alanine amidase
N1207_07100	COG1388	LysM domain
N1207_07110	COG4195	phage-related replication protein
N1207_07115	COG3546	catalase activity
N1207_07120	COG2856	Zn peptidase
N1207_07125	COG1396	sequence-specific DNA binding
N1207_07135	COG1522	sequence-specific DNA binding
N1207_07140	COG1484	DNA-dependent DNA replication
N1207_07160	COG1595	DNA-templated transcription, initiation
N1207_07165	COG5484	DNA packaging
N1207_07165	COG3728	DNA packaging
N1207_07170	COG1783	phage Terminase large subunit
N1207_07175	COG5518	Phage portal protein
N1207_07180	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N1207_07185	COG4653	Phage capsid family
N1207_07235	COG3953	SLT domain
N1207_07235	COG5412	phage tail tape measure protein
N1207_07240	COG1652	LysM domain
N1207_07245	COG4193	domain, Protein
N1207_07255	COG3628	GPW Gp25 family protein
N1207_07260	COG3299	homolog of phage Mu protein gp47
N1207_07265	COG3778	Protein conserved in bacteria
N1207_07305	COG5632	N-Acetylmuramoyl-L-alanine amidase
N1207_07305	COG3409	Peptidoglycan-binding domain 1 protein
N1207_07325	COG0306	phosphate transporter
N1207_07330	COG1392	Phosphate transport regulator
N1207_07335	COG0531	amino acid
N1207_07340	COG0346	lactoylglutathione lyase activity
N1207_07350	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N1207_07355	COG0463	Glycosyl transferase, family 2
N1207_07365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N1207_07370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N1207_07375	COG2362	D-Aminopeptidase
N1207_07380	COG0601	transmembrane transport
N1207_07385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N1207_07390	COG0444	Belongs to the ABC transporter superfamily
N1207_07395	COG4166	transmembrane transport
N1207_07400	COG1619	proteins homologs of microcin C7 resistance protein MccF
N1207_07405	COG4948	Mandelate Racemase Muconate Lactonizing
N1207_07410	COG0791	NLP P60 protein
N1207_07415	COG4608	Belongs to the ABC transporter superfamily
N1207_07420	COG2706	6-phosphogluconolactonase activity
N1207_07425	COG1834	amidinotransferase
N1207_07430	COG1607	acyl-coa hydrolase
N1207_07435	COG1017	nitric oxide dioxygenase activity
N1207_07435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N1207_07445	COG2323	membrane
N1207_07450	COG2318	DinB family
N1207_07455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N1207_07460	COG2076	Multidrug Resistance protein
N1207_07465	COG2076	Multidrug Resistance protein
N1207_07470	COG0788	formyltetrahydrofolate deformylase activity
N1207_07475	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N1207_07480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N1207_07485	COG1764	response to oxidative stress
N1207_07490	COG1846	Transcriptional regulator
N1207_07495	COG1764	response to oxidative stress
N1207_07505	COG0590	tRNA wobble adenosine to inosine editing
N1207_07510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N1207_07515	COG1404	Belongs to the peptidase S8 family
N1207_07520	COG1366	Belongs to the anti-sigma-factor antagonist family
N1207_07525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N1207_07530	COG1122	ATPase activity
N1207_07535	COG4721	ABC-type cobalt transport system, permease component
N1207_07545	COG0745	RESPONSE REGULATOR receiver
N1207_07550	COG5002	protein histidine kinase activity
N1207_07550	COG3850	Histidine kinase
N1207_07555	COG3212	peptidase
N1207_07560	COG3212	peptidase
N1207_07575	COG2239	Acts as a magnesium transporter
N1207_07580	COG0789	Transcriptional regulator
N1207_07595	COG1846	Transcriptional regulator
N1207_07600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N1207_07605	COG0726	polysaccharide deacetylase
N1207_07610	COG1408	metallophosphoesterase
N1207_07620	COG0463	Glycosyl transferase, family 2
N1207_07625	COG3285	dna ligase
N1207_07625	COG1793	dna ligase
N1207_07630	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
N1207_07635	COG5001	Diguanylate cyclase
N1207_07635	COG3300	MHYT domain
N1207_07640	COG0586	Pfam SNARE associated Golgi protein
N1207_07645	COG0861	Integral membrane protein TerC family
N1207_07650	COG1191	sigma factor activity
N1207_07670	COG0501	Belongs to the peptidase M48B family
N1207_07675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N1207_07690	COG3594	Acyltransferase
N1207_07695	COG5002	protein histidine kinase activity
N1207_07700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N1207_07710	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N1207_07715	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
N1207_07720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N1207_07725	COG0436	Aminotransferase
N1207_07730	COG1850	ribulose-bisphosphate carboxylase activity
N1207_07735	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
N1207_07740	COG0235	Class ii aldolase
N1207_07745	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
N1207_07750	COG3339	Conserved Protein
N1207_07765	COG3852	Histidine kinase
N1207_07770	COG1846	Transcriptional regulator
N1207_07775	COG1360	Flagellar Motor Protein
N1207_07780	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N1207_07785	COG0542	response to heat
N1207_07790	COG3949	Membrane
N1207_07795	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N1207_07800	COG0720	synthase
N1207_07805	COG0602	queuosine metabolic process
N1207_07810	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N1207_07815	COG1733	regulation of RNA biosynthetic process
N1207_07820	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_07825	COG1388	LysM domain
N1207_07825	COG4641	Protein conserved in bacteria
N1207_07830	COG1388	LysM domain
N1207_07835	COG3858	chitin binding
N1207_07845	COG4873	Protein conserved in bacteria
N1207_07855	COG3773	Cell wall hydrolase
N1207_07860	COG2244	polysaccharide biosynthetic process
N1207_07865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N1207_07870	COG2217	Heavy metal translocating P-type atpase
N1207_07880	COG0006	proline dipeptidase activity
N1207_07885	COG1609	Transcriptional regulator
N1207_07890	COG3711	transcriptional antiterminator
N1207_07895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_07895	COG2190	(PTS) system
N1207_07895	COG1263	PTS System
N1207_07900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N1207_07905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N1207_07915	COG1533	DNA photolyase activity
N1207_07920	COG0456	acetyltransferase
N1207_07925	COG0840	transmembrane signaling receptor activity
N1207_07930	COG2084	Dehydrogenase
N1207_07935	COG4257	antibiotic catabolic process
N1207_07940	COG2340	Cysteine-rich secretory protein family
N1207_07945	COG0768	penicillin binding
N1207_07950	COG4191	Histidine kinase
N1207_07955	COG0436	Aminotransferase
N1207_07965	COG0784	Response regulator, receiver
N1207_07965	COG0835	chemotaxis
N1207_07975	COG2814	Major facilitator Superfamily
N1207_07980	COG1376	ErfK ybiS ycfS ynhG family protein
N1207_07985	COG1408	metallophosphoesterase
N1207_07990	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_07995	COG2200	EAL domain
N1207_08000	COG4703	Protein of unknown function (DUF1797)
N1207_08005	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
N1207_08015	COG0517	IMP dehydrogenase activity
N1207_08020	COG0583	DNA-binding transcription factor activity
N1207_08025	COG0716	FMN binding
N1207_08035	COG0716	FMN binding
N1207_08040	COG2171	N-acyltransferase activity
N1207_08045	COG1473	amidohydrolase
N1207_08055	COG0668	transmembrane transport
N1207_08060	COG0450	alkyl hydroperoxide reductase
N1207_08065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N1207_08080	COG0746	molybdenum cofactor guanylyltransferase activity
N1207_08085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N1207_08090	COG0303	'Molybdopterin
N1207_08095	COG1763	Mo-molybdopterin cofactor biosynthetic process
N1207_08100	COG0314	molybdopterin synthase activity
N1207_08105	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N1207_08110	COG1132	(ABC) transporter
N1207_08115	COG1132	(ABC) transporter
N1207_08125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N1207_08130	COG1136	(ABC) transporter
N1207_08135	COG0577	efflux transmembrane transporter activity
N1207_08140	COG1349	DNA-binding transcription factor activity
N1207_08145	COG1105	Belongs to the carbohydrate kinase PfkB family
N1207_08150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N1207_08150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N1207_08150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N1207_08155	COG0681	Belongs to the peptidase S26 family
N1207_08165	COG0488	(ABC) transporter
N1207_08170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N1207_08175	COG2309	aminopeptidase activity
N1207_08185	COG1077	Cell shape determining protein MreB Mrl
N1207_08190	COG2002	toxin-antitoxin pair type II binding
N1207_08195	COG3852	Histidine kinase
N1207_08200	COG2105	PFAM AIG2 family protein
N1207_08200	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
N1207_08205	COG0569	domain protein
N1207_08210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N1207_08215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N1207_08220	COG5503	Protein of unknown function (DUF1447)
N1207_08225	COG0561	phosphatase activity
N1207_08230	COG0242	peptide deformylase activity
N1207_08240	COG0497	DNA recombination
N1207_08245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N1207_08250	COG0022	dehydrogenase e1 component
N1207_08255	COG0508	dehydrogenase complex catalyzes the overall conversion of
N1207_08260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N1207_08265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N1207_08275	COG1982	Orn Lys Arg decarboxylase major
N1207_08280	COG4476	Belongs to the UPF0223 family
N1207_08285	COG4493	Belongs to the UPF0637 family
N1207_08295	COG0483	inositol monophosphate 1-phosphatase activity
N1207_08305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
N1207_08345	COG1217	gtp-binding protein TYPA
N1207_08355	COG4896	Protein conserved in bacteria
N1207_08365	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N1207_08370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N1207_08375	COG2066	Belongs to the glutaminase family
N1207_08380	COG4838	Belongs to the UPF0358 family
N1207_08385	COG0772	Belongs to the SEDS family
N1207_08390	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N1207_08395	COG1612	heme a metabolic process
N1207_08400	COG0109	protoheme IX farnesyltransferase activity
N1207_08405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N1207_08405	COG2010	Cytochrome c
N1207_08410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N1207_08415	COG1845	cytochrome c oxidase, subunit III
N1207_08420	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N1207_08425	COG3336	cytochrome c oxidase
N1207_08435	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
N1207_08440	COG2340	Cysteine-rich secretory protein family
N1207_08455	COG3679	Belongs to the UPF0342 family
N1207_08460	COG4471	UPF0298 protein
N1207_08465	COG0742	ribosomal rna small subunit methyltransferase
N1207_08470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N1207_08475	COG3314	Sporulation integral membrane protein YlbJ
N1207_08480	COG1752	Esterase of the alpha-beta hydrolase superfamily
N1207_08485	COG3480	Lon protease (S16) C-terminal proteolytic domain
N1207_08490	COG1323	Belongs to the UPF0348 family
N1207_08500	COG1399	metal-binding, possibly nucleic acid-binding protein
N1207_08515	COG0454	-acetyltransferase
N1207_08520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N1207_08525	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
N1207_08530	COG2001	Belongs to the MraZ family
N1207_08535	COG0275	rRNA processing
N1207_08540	COG4839	cell division protein FtsL
N1207_08545	COG0768	penicillin binding
N1207_08550	COG0768	penicillin binding
N1207_08555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N1207_08560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N1207_08565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N1207_08570	COG0772	Belongs to the SEDS family
N1207_08575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N1207_08580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N1207_08585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N1207_08590	COG3879	Bacterial protein of unknown function (DUF881)
N1207_08595	COG3879	Bacterial protein of unknown function (DUF881)
N1207_08600	COG3856	small basic protein
N1207_08605	COG0849	cell division
N1207_08610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N1207_08615	COG4412	M6 family metalloprotease domain protein
N1207_08615	COG1404	Belongs to the peptidase S8 family
N1207_08625	COG1191	sigma factor activity
N1207_08630	COG1191	sigma factor activity
N1207_08635	COG1119	ATPase activity
N1207_08640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N1207_08645	COG1873	PFAM PRC-barrel domain
N1207_08650	COG1496	oxidoreductase activity
N1207_08655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N1207_08660	COG1799	cell septum assembly
N1207_08665	COG0762	integral membrane protein
N1207_08670	COG2302	S4 RNA-binding domain
N1207_08675	COG3599	regulation of cell shape
N1207_08680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N1207_08685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N1207_08690	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N1207_08695	COG0564	pseudouridine synthase activity
N1207_08700	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
N1207_08705	COG2233	PERMEase
N1207_08710	COG0540	Belongs to the ATCase OTCase family
N1207_08715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N1207_08720	COG0505	Belongs to the CarA family
N1207_08725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N1207_08730	COG0543	2 iron, 2 sulfur cluster binding
N1207_08735	COG0167	dihydroorotate dehydrogenase activity
N1207_08740	COG0284	orotidine-5'-phosphate decarboxylase activity
N1207_08745	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N1207_08750	COG0175	sulfate reduction
N1207_08755	COG0306	phosphate transporter
N1207_08760	COG2046	Belongs to the sulfate adenylyltransferase family
N1207_08765	COG0529	Catalyzes the synthesis of activated sulfate
N1207_08770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N1207_08775	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
N1207_08780	COG1648	precorrin-2 dehydrogenase activity
N1207_08785	COG1293	RNA-binding protein homologous to eukaryotic snRNP
N1207_08790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N1207_08795	COG1561	YicC-like family, N-terminal region
N1207_08805	COG0194	GDP metabolic process
N1207_08810	COG1758	RNA polymerase activity
N1207_08815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N1207_08820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N1207_08825	COG0242	peptide deformylase activity
N1207_08830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N1207_08835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N1207_08835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N1207_08840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N1207_08845	COG0631	protein serine/threonine phosphatase activity
N1207_08850	COG0515	serine threonine protein kinase
N1207_08850	COG2815	serine threonine protein kinase
N1207_08855	COG1162	GTPase activity
N1207_08860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N1207_08865	COG1564	THIamine pyrophosphokinase
N1207_08875	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N1207_08880	COG1302	Protein conserved in bacteria
N1207_08885	COG1461	Dihydroxyacetone kinase
N1207_08890	COG1760	l-serine dehydratase
N1207_08895	COG1760	l-serine dehydratase
N1207_08900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N1207_08905	COG1349	DNA-binding transcription factor activity
N1207_08905	COG2050	protein possibly involved in aromatic compounds catabolism
N1207_08910	COG0416	fatty acid biosynthetic process
N1207_08915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N1207_08920	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_08930	COG0571	ribonuclease III activity
N1207_08935	COG1196	nuclear chromosome segregation
N1207_08940	COG0552	protein localization to endoplasmic reticulum
N1207_08950	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
N1207_08955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N1207_08960	COG0228	four-way junction DNA binding
N1207_08965	COG1837	Belongs to the UPF0109 family
N1207_08975	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N1207_08980	COG0336	Belongs to the RNA methyltransferase TrmD family
N1207_08985	COG0335	large ribosomal subunit rRNA binding
N1207_08990	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N1207_08995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N1207_09005	COG2257	FlhB HrpN YscU SpaS Family
N1207_09010	COG0045	succinate-CoA ligase (ADP-forming) activity
N1207_09015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N1207_09020	COG0758	DNA mediated transformation
N1207_09025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N1207_09030	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
N1207_09035	COG4974	Belongs to the 'phage' integrase family
N1207_09040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N1207_09045	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N1207_09050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N1207_09055	COG1815	bacterial-type flagellum-dependent cell motility
N1207_09060	COG1558	bacterial-type flagellum-dependent cell motility
N1207_09065	COG1677	Flagellar hook-basal body complex protein FliE
N1207_09070	COG1766	The M ring may be actively involved in energy transduction
N1207_09075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N1207_09080	COG1317	bacterial-type flagellum organization
N1207_09085	COG1157	protein secretion by the type III secretion system
N1207_09090	COG2882	bacterial-type flagellum organization
N1207_09095	COG3334	PFAM MgtE intracellular
N1207_09100	COG3144	bacterial-type flagellum assembly
N1207_09105	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N1207_09110	COG4786	Flagellar basal body rod
N1207_09115	COG1582	Flagellar protein (FlbD)
N1207_09120	COG1580	Controls the rotational direction of flagella during chemotaxis
N1207_09125	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N1207_09130	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N1207_09130	COG1776	CheC inhibitor of MCP methylation
N1207_09135	COG2201	protein-glutamate methylesterase activity
N1207_09140	COG3190	flagellar
N1207_09145	COG1338	Plays a role in the flagellum-specific transport system
N1207_09150	COG1987	bacterial-type flagellum assembly
N1207_09155	COG1684	flagellar biosynthetic protein fliR
N1207_09160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N1207_09165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N1207_09170	COG1419	protein localization to endoplasmic reticulum
N1207_09175	COG0455	bacterial-type flagellum organization
N1207_09180	COG2201	protein-glutamate methylesterase activity
N1207_09185	COG2198	Histidine kinase
N1207_09185	COG0643	Histidine kinase
N1207_09190	COG0835	chemotaxis
N1207_09195	COG1776	CheC inhibitor of MCP methylation
N1207_09200	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N1207_09205	COG1191	sigma factor activity
N1207_09215	COG0052	Belongs to the universal ribosomal protein uS2 family
N1207_09220	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N1207_09225	COG0528	UMP kinase activity
N1207_09230	COG0233	cytoplasmic translational termination
N1207_09235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N1207_09240	COG4589	Belongs to the CDS family
N1207_09245	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N1207_09250	COG0750	zinc metalloprotease
N1207_09255	COG0442	prolyl-tRNA aminoacylation
N1207_09260	COG2176	DNA-directed DNA polymerase activity
N1207_09285	COG0779	Required for maturation of 30S ribosomal subunits
N1207_09290	COG0195	Participates in both transcription termination and antitermination
N1207_09295	COG2740	Nucleic-acid-binding protein implicated in transcription termination
N1207_09300	COG1358	cellular component organization or biogenesis
N1207_09305	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N1207_09310	COG1550	Protein conserved in bacteria
N1207_09315	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N1207_09320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N1207_09325	COG0196	riboflavin kinase activity
N1207_09330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N1207_09335	COG1185	polyribonucleotide nucleotidyltransferase activity
N1207_09340	COG0726	polysaccharide deacetylase
N1207_09345	COG0612	Peptidase, M16
N1207_09350	COG1873	PFAM PRC-barrel domain
N1207_09355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N1207_09360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N1207_09365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N1207_09370	COG0527	aspartate kinase activity
N1207_09375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N1207_09380	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N1207_09385	COG0740	serine-type endopeptidase activity
N1207_09395	COG4980	gas vesicle protein
N1207_09395	COG1674	ftsk spoiiie
N1207_09400	COG2188	Transcriptional regulator
N1207_09405	COG2814	Major facilitator Superfamily
N1207_09410	COG0612	Peptidase, M16
N1207_09415	COG0612	Peptidase, M16
N1207_09420	COG0300	oxidoreductase activity
N1207_09435	COG1426	Protein conserved in bacteria
N1207_09440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N1207_09445	COG1546	Belongs to the CinA family
N1207_09445	COG1058	Belongs to the CinA family
N1207_09450	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N1207_09455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N1207_09460	COG1418	mRNA catabolic process
N1207_09465	COG1692	metallophosphoesterase
N1207_09470	COG2359	stage V sporulation protein S
N1207_09475	COG1063	alcohol dehydrogenase
N1207_09480	COG0156	8-amino-7-oxononanoate synthase activity
N1207_09485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N1207_09490	COG4550	Control of competence regulator ComK, YlbF/YmcA
N1207_09500	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N1207_09505	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N1207_09520	COG3226	Transcriptional regulator
N1207_09525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N1207_09535	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N1207_09540	COG3321	synthase
N1207_09545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N1207_09545	COG2070	2-Nitropropane dioxygenase
N1207_09550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N1207_09555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N1207_09560	COG3425	synthase
N1207_09565	COG1024	Enoyl-CoA hydratase
N1207_09570	COG1024	Enoyl-CoA hydratase
N1207_09575	COG3321	synthase
N1207_09575	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_09575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_09575	COG0318	PFAM AMP-dependent synthetase and ligase
N1207_09575	COG0300	oxidoreductase activity
N1207_09580	COG4221	oxidoreductase activity
N1207_09580	COG0300	oxidoreductase activity
N1207_09580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N1207_09580	COG3321	synthase
N1207_09585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N1207_09585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N1207_09585	COG3321	synthase
N1207_09585	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_09585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_09590	COG4221	oxidoreductase activity
N1207_09590	COG3321	synthase
N1207_09590	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_09590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_09595	COG3321	synthase
N1207_09595	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N1207_09595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N1207_09595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N1207_09600	COG2124	cytochrome p450
N1207_09610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N1207_09615	COG1404	Belongs to the peptidase S8 family
N1207_09625	COG4195	phage-related replication protein
N1207_09630	COG1764	response to oxidative stress
N1207_09635	COG2076	Multidrug Resistance protein
N1207_09640	COG2076	Multidrug Resistance protein
N1207_09655	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N1207_09660	COG1923	regulation of RNA biosynthetic process
N1207_09675	COG1780	Probably involved in ribonucleotide reductase function
N1207_09680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N1207_09685	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N1207_09690	COG4112	unkown
N1207_09695	COG0860	N-Acetylmuramoyl-L-alanine amidase
N1207_09700	COG0464	growth
N1207_09705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N1207_09710	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
N1207_09715	COG0789	Transcriptional regulator
N1207_09720	COG0174	glutamine synthetase
N1207_09745	COG4282	regulation of fungal-type cell wall biogenesis
N1207_09755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N1207_09785	COG0135	phosphoribosylanthranilate isomerase activity
N1207_09790	COG2211	Major facilitator Superfamily
N1207_09795	COG3507	Belongs to the glycosyl hydrolase 43 family
N1207_09800	COG1940	carbohydrate kinase activity
N1207_09805	COG2115	Belongs to the xylose isomerase family
N1207_09810	COG1070	Carbohydrate kinase
N1207_09825	COG2814	Major facilitator Superfamily
N1207_09830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N1207_09845	COG0756	dUTP diphosphatase activity
N1207_09885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N1207_09900	COG3832	glyoxalase III activity
N1207_09915	COG0697	spore germination
N1207_09920	COG0531	amino acid
N1207_09950	COG4195	phage-related replication protein
N1207_09960	COG0346	lactoylglutathione lyase activity
N1207_09970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N1207_09975	COG1388	LysM domain
N1207_09980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N1207_09985	COG4224	UPF0291 protein
N1207_09990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N1207_10000	COG3763	UPF0154 protein
N1207_10010	COG0785	Cytochrome C biogenesis protein
N1207_10015	COG2201	protein-glutamate methylesterase activity
N1207_10020	COG4846	Membrane protein involved in cytochrome C biogenesis
N1207_10030	COG0071	Belongs to the small heat shock protein (HSP20) family
N1207_10045	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N1207_10050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N1207_10070	COG0824	Thioesterase
N1207_10080	COG4841	protein insertion into membrane
N1207_10085	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N1207_10090	COG1832	CoA-binding protein
N1207_10095	COG0187	DNA topoisomerase II activity
N1207_10100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N1207_10115	COG1115	amino acid carrier protein
N1207_10120	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
N1207_10130	COG5520	Belongs to the glycosyl hydrolase 30 family
N1207_10135	COG3507	Belongs to the glycosyl hydrolase 43 family
N1207_10140	COG2246	polysaccharide biosynthetic process
N1207_10145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N1207_10150	COG0586	Pfam SNARE associated Golgi protein
N1207_10155	COG2404	hydrolase activity, acting on ester bonds
N1207_10160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N1207_10165	COG1024	Enoyl-CoA hydratase
N1207_10170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N1207_10175	COG0511	ligase activity, forming carbon-carbon bonds
N1207_10180	COG0439	Biotin carboxylase
N1207_10185	COG0318	PFAM AMP-dependent synthetase and ligase
N1207_10190	COG1960	acyl-CoA dehydrogenase activity
N1207_10200	COG1649	PFAM Uncharacterised BCR, COG1649
N1207_10210	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N1207_10210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_10215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_10220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_10225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_10230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_10235	COG2027	D-alanyl-D-alanine carboxypeptidase
N1207_10240	COG2017	converts alpha-aldose to the beta-anomer
N1207_10245	COG0534	Mate efflux family protein
N1207_10260	COG0582	viral genome integration into host DNA
N1207_10265	COG0166	Belongs to the GPI family
N1207_10270	COG0405	Gamma-glutamyltransferase
N1207_10275	COG0583	DNA-binding transcription factor activity
N1207_10285	COG0493	'glutamate synthase
N1207_10290	COG0070	glutamate synthase
N1207_10290	COG0067	glutamate synthase
N1207_10290	COG0069	glutamate synthase activity
N1207_10295	COG0583	DNA-binding transcription factor activity
N1207_10300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N1207_10305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N1207_10315	COG0300	oxidoreductase activity
N1207_10320	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N1207_10330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N1207_10345	COG1131	(ABC) transporter
N1207_10355	COG2814	Major facilitator Superfamily
N1207_10360	COG1070	Carbohydrate kinase
N1207_10365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N1207_10370	COG0243	molybdopterin cofactor binding
N1207_10380	COG2814	Major facilitator Superfamily
N1207_10385	COG0673	inositol 2-dehydrogenase activity
N1207_10390	COG1082	Xylose isomerase domain protein TIM barrel
N1207_10395	COG1609	Transcriptional regulator
N1207_10415	COG5278	phosphoserine phosphatase activity
N1207_10415	COG0840	transmembrane signaling receptor activity
N1207_10420	COG2368	4-hydroxyphenylacetate
N1207_10425	COG4305	rare lipoprotein A
N1207_10430	COG3619	membrane
N1207_10435	COG3866	Pectate lyase
N1207_10440	COG2135	peptidase activity
N1207_10450	COG2140	Oxalate decarboxylase
N1207_10475	COG2720	vancomycin resistance protein
N1207_10490	COG3739	integral membrane protein
N1207_10495	COG0583	DNA-binding transcription factor activity
N1207_10500	COG0697	spore germination
N1207_10510	COG0693	protein deglycase activity
N1207_10515	COG2367	Beta-lactamase
N1207_10535	COG0574	Belongs to the PEP-utilizing enzyme family
N1207_10535	COG3848	Pyruvate phosphate dikinase
N1207_10540	COG0726	polysaccharide deacetylase
N1207_10545	COG2314	TM2 domain
N1207_10600	COG0457	Tetratricopeptide repeat
N1207_10625	COG4282	regulation of fungal-type cell wall biogenesis
N1207_10630	COG1231	oxidoreductase activity
N1207_10635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N1207_10640	COG0662	Cupin 2, conserved barrel domain protein
N1207_10640	COG2207	Transcriptional regulator
N1207_10645	COG0456	acetyltransferase
N1207_10650	COG1309	transcriptional regulator
N1207_10655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N1207_10660	COG3708	Transcriptional regulator
N1207_10665	COG2378	regulation of single-species biofilm formation
N1207_10675	COG0640	Transcriptional regulator
N1207_10680	COG0741	lytic transglycosylase activity
N1207_10685	COG2322	membrane
N1207_10700	COG1619	proteins homologs of microcin C7 resistance protein MccF
N1207_10705	COG3239	Fatty acid desaturase
N1207_10710	COG4585	Histidine kinase
N1207_10715	COG2197	response regulator
N1207_10720	COG3584	3D domain protein
N1207_10720	COG1388	LysM domain
N1207_10725	COG0514	ATP-dependent DNA helicase (RecQ)
N1207_10735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N1207_10740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N1207_10755	COG0071	Belongs to the small heat shock protein (HSP20) family
N1207_10780	COG1012	belongs to the aldehyde dehydrogenase family
N1207_10785	COG1657	PFAM Prenyltransferase squalene oxidase
N1207_10790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N1207_10795	COG0733	neurotransmitter:sodium symporter activity
N1207_10800	COG0385	Bile acid
N1207_10805	COG0508	dehydrogenase complex catalyzes the overall conversion of
N1207_10810	COG0567	Dehydrogenase, E1 component
N1207_10815	COG4548	von Willebrand factor, type A
N1207_10820	COG0714	Associated with various cellular activities
N1207_10825	COG2032	superoxide dismutase activity
N1207_10830	COG0791	NLP P60 protein
N1207_10830	COG1388	LysM domain
N1207_10835	COG1819	glycosyl
N1207_10840	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N1207_10845	COG0534	Mate efflux family protein
N1207_10850	COG1366	Belongs to the anti-sigma-factor antagonist family
N1207_10855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N1207_10860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N1207_10870	COG2962	Rard protein
N1207_10885	COG2610	gluconate transmembrane transporter activity
N1207_10890	COG1942	4-Oxalocrotonate Tautomerase
N1207_10895	COG1733	regulation of RNA biosynthetic process
N1207_10900	COG0778	Nitroreductase
N1207_10905	COG0400	carboxylic ester hydrolase activity
N1207_10910	COG0346	lactoylglutathione lyase activity
N1207_10920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N1207_10925	COG0793	Belongs to the peptidase S41A family
N1207_10925	COG3409	Peptidoglycan-binding domain 1 protein
N1207_10930	COG2226	methyltransferase
N1207_10940	COG1876	peptidase activity
N1207_10945	COG0813	purine-nucleoside phosphorylase activity
N1207_10960	COG0671	phosphoesterase, PA-phosphatase related
N1207_10980	COG4479	Belongs to the UPF0346 family
N1207_11010	COG3331	DNA recombination
N1207_11055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N1207_11090	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
N1207_11095	COG0756	dUTP diphosphatase activity
N1207_11100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N1207_11130	COG1780	Probably involved in ribonucleotide reductase function
N1207_11230	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N1207_11255	COG3584	3D domain protein
N1207_11260	COG0587	DNA-directed DNA polymerase activity
N1207_11265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N1207_11270	COG0358	DNA primase activity
N1207_11275	COG0305	Participates in initiation and elongation during chromosome replication
N1207_11285	COG2887	Belongs to the helicase family. UvrD subfamily
N1207_11320	COG2135	peptidase activity
N1207_11325	COG1793	dna ligase
N1207_11365	COG1388	LysM domain
N1207_11425	COG3655	Transcriptional regulator
N1207_11440	COG0582	viral genome integration into host DNA
N1207_11500	COG3655	Transcriptional regulator
N1207_11575	COG0776	regulation of translation
N1207_11615	COG4373	Mu-like prophage FluMu protein gp28
N1207_11715	COG0582	viral genome integration into host DNA
N1207_11735	COG0741	lytic transglycosylase activity
N1207_11735	COG1196	nuclear chromosome segregation
N1207_11735	COG0739	heme binding
N1207_11745	COG2433	Pfam Transposase IS66
N1207_11755	COG4632	Exopolysaccharide biosynthesis protein
N1207_11755	COG5434	Belongs to the glycosyl hydrolase 28 family
N1207_11760	COG5632	N-Acetylmuramoyl-L-alanine amidase
N1207_11775	COG0457	Tetratricopeptide repeat
N1207_11780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N1207_11790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N1207_11795	COG2226	methyltransferase
N1207_11800	COG2211	Major facilitator Superfamily
N1207_11805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N1207_11835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N1207_11855	COG5444	nuclease activity
N1207_11860	COG4282	regulation of fungal-type cell wall biogenesis
N1207_11875	COG1525	nuclease
N1207_11885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N1207_11895	COG0456	acetyltransferase
N1207_11900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N1207_11905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N1207_11910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N1207_11915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N1207_11930	COG0456	acetyltransferase
N1207_11935	COG0463	Glycosyl transferase, family 2
N1207_11950	COG4641	Protein conserved in bacteria
N1207_11955	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
N1207_11960	COG1086	Polysaccharide biosynthesis protein
N1207_11965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N1207_11970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N1207_11975	COG1846	Transcriptional regulator
N1207_11980	COG0534	Mate efflux family protein
N1207_11990	COG4698	Protein conserved in bacteria
N1207_11995	COG2755	lipolytic protein G-D-S-L family
N1207_12000	COG1999	signal sequence binding
N1207_12010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N1207_12015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N1207_12020	COG1272	protein, Hemolysin III
N1207_12025	COG0204	Acyl-transferase
N1207_12030	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N1207_12035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N1207_12045	COG2136	Putative SAM-dependent methyltransferase
N1207_12045	COG2521	methyltransferase
N1207_12055	COG0129	dihydroxy-acid dehydratase activity
N1207_12060	COG1413	lyase activity
N1207_12065	COG1418	mRNA catabolic process
N1207_12070	COG0386	Belongs to the glutathione peroxidase family
N1207_12075	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
N1207_12080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N1207_12090	COG1278	Cold shock
N1207_12110	COG0328	RNA-DNA hybrid ribonuclease activity
N1207_12115	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N1207_12120	COG0328	RNA-DNA hybrid ribonuclease activity
N1207_12130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N1207_12145	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N1207_12155	COG1755	Isoprenylcysteine carboxyl methyltransferase
N1207_12160	COG3424	synthase
N1207_12165	COG2233	PERMEase
N1207_12170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N1207_12175	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N1207_12185	COG0800	Aldolase
N1207_12190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N1207_12195	COG1609	Transcriptional regulator
N1207_12200	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
N1207_12205	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_12210	COG1199	ATP-dependent helicase activity
N1207_12225	COG0116	Belongs to the methyltransferase superfamily
N1207_12240	COG4474	Belongs to the UPF0398 family
N1207_12255	COG3359	exonuclease
N1207_12260	COG1205	dead DEAH box helicase
N1207_12260	COG1111	helicase
N1207_12265	COG2190	(PTS) system
N1207_12270	COG0071	Belongs to the small heat shock protein (HSP20) family
N1207_12305	COG3331	DNA recombination
N1207_12310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N1207_12310	COG4499	WXG100 protein secretion system (Wss), protein YukC
N1207_12320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N1207_12325	COG3935	DnaD domain protein
N1207_12330	COG0017	Asparaginyl-tRNA synthetase
N1207_12335	COG0436	Aminotransferase
N1207_12340	COG5353	protein conserved in bacteria
N1207_12350	COG1199	ATP-dependent helicase activity
N1207_12350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N1207_12355	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
N1207_12360	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N1207_12365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N1207_12370	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
N1207_12370	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
N1207_12375	COG0617	tRNA 3'-terminal CCA addition
N1207_12380	COG0438	transferase activity, transferring glycosyl groups
N1207_12385	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N1207_12390	COG1803	Methylglyoxal synthase
N1207_12395	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N1207_12400	COG1694	Mazg nucleotide pyrophosphohydrolase
N1207_12405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N1207_12415	COG4347	Protein of unknown function (DUF1405)
N1207_12420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N1207_12420	COG2010	Cytochrome c
N1207_12425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N1207_12430	COG0723	plastoquinol--plastocyanin reductase activity
N1207_12440	COG5582	Belongs to the UPF0302 family
N1207_12445	COG0457	Tetratricopeptide repeat
N1207_12450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N1207_12455	COG0287	Prephenate dehydrogenase
N1207_12460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N1207_12470	COG0133	tryptophan synthase activity
N1207_12475	COG0135	phosphoribosylanthranilate isomerase activity
N1207_12485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N1207_12490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N1207_12495	COG4401	Chorismate mutase type I
N1207_12500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N1207_12505	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N1207_12510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N1207_12515	COG0105	UTP biosynthetic process
N1207_12520	COG0142	geranyltranstransferase activity
N1207_12525	COG2226	methyltransferase
N1207_12530	COG0142	geranyltranstransferase activity
N1207_12540	COG0302	gtp cyclohydrolase
N1207_12545	COG0776	regulation of translation
N1207_12550	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N1207_12565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N1207_12595	COG1304	FMN binding
N1207_12600	COG0539	negative regulation of cytoplasmic translation
N1207_12605	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N1207_12615	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
N1207_12620	COG2959	enzyme of heme biosynthesis
N1207_12625	COG3773	Cell wall hydrolase
N1207_12625	COG3409	Peptidoglycan-binding domain 1 protein
N1207_12630	COG2339	peptidase activity
N1207_12635	COG0492	ferredoxin-NADP+ reductase activity
N1207_12640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N1207_12645	COG4862	establishment of competence for transformation
N1207_12650	COG1408	metallophosphoesterase
N1207_12660	COG1388	LysM domain
N1207_12665	COG1266	CAAX protease self-immunity
N1207_12670	COG0514	ATP-dependent DNA helicase (RecQ)
N1207_12675	COG4955	Helix-turn-helix domain
N1207_12680	COG1141	Ferredoxin
N1207_12685	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
N1207_12690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N1207_12695	COG0710	3-dehydroquinate dehydratase activity
N1207_12705	COG1595	DNA-templated transcription, initiation
N1207_12710	COG5002	protein histidine kinase activity
N1207_12715	COG0745	RESPONSE REGULATOR receiver
N1207_12720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N1207_12725	COG1333	cytochrome c biogenesis protein
N1207_12730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N1207_12735	COG1187	pseudouridine synthase activity
N1207_12740	COG0700	Nucleoside recognition
N1207_12745	COG2715	membrane protein required for spore maturation
N1207_12750	COG1686	Belongs to the peptidase S11 family
N1207_12760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N1207_12765	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N1207_12770	COG1547	Domain of unknown function (DUF309)
N1207_12775	COG0456	acetyltransferase
N1207_12780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N1207_12785	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N1207_12785	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N1207_12790	COG0307	riboflavin synthase, alpha
N1207_12795	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N1207_12795	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N1207_12805	COG0681	Belongs to the peptidase S26 family
N1207_12825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N1207_12830	COG4086	secreted protein
N1207_12835	COG0019	diaminopimelate decarboxylase activity
N1207_12840	COG0697	spore germination
N1207_12855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N1207_12875	COG1191	sigma factor activity
N1207_12880	COG2172	sigma factor antagonist activity
N1207_12885	COG1366	Belongs to the anti-sigma-factor antagonist family
N1207_12890	COG1686	Belongs to the peptidase S11 family
N1207_12895	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
N1207_12900	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N1207_12905	COG4974	Belongs to the 'phage' integrase family
N1207_12915	COG0735	belongs to the Fur family
N1207_12920	COG1300	Membrane
N1207_12930	COG0281	malic enzyme
N1207_12935	COG1757	Na H antiporter
N1207_12940	COG1027	Aspartate ammonia-lyase
N1207_12945	COG0252	asparaginase activity
N1207_12950	COG1396	sequence-specific DNA binding
N1207_12955	COG1379	DNA repair
N1207_12960	COG0494	nUDIX hydrolase
N1207_12970	COG0667	Aldo Keto reductase
N1207_12980	COG1073	alpha beta
N1207_12990	COG4918	Iron-sulphur cluster biosynthesis
N1207_12995	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N1207_12995	COG0456	acetyltransferase
N1207_13000	COG2329	Antibiotic biosynthesis monooxygenase
N1207_13005	COG0456	acetyltransferase
N1207_13015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N1207_13025	COG2211	Major facilitator Superfamily
N1207_13035	COG0346	lactoylglutathione lyase activity
N1207_13040	COG1072	(Pantothenic acid kinase))
N1207_13045	COG3048	D-serine ammonia-lyase activity
N1207_13050	COG0300	oxidoreductase activity
N1207_13055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N1207_13060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N1207_13065	COG4187	Peptidase family M20/M25/M40
N1207_13070	COG1902	pentaerythritol trinitrate reductase activity
N1207_13075	COG0596	Alpha beta hydrolase
N1207_13085	COG1234	tRNA 3'-trailer cleavage
N1207_13090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N1207_13095	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N1207_13100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N1207_13110	COG0706	membrane insertase activity
N1207_13115	COG3361	conserved protein (COG2071)
N1207_13120	COG2195	Cleaves the N-terminal amino acid of tripeptides
N1207_13125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N1207_13130	COG0346	lactoylglutathione lyase activity
N1207_13140	COG1376	ErfK ybiS ycfS ynhG family protein
N1207_13145	COG4129	membrane
N1207_13150	COG1126	abc transporter atp-binding protein
N1207_13155	COG0765	amino acid transport
N1207_13160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N1207_13170	COG1597	lipid kinase activity
N1207_13175	COG2814	Major facilitator Superfamily
N1207_13180	COG0789	Transcriptional regulator
N1207_13180	COG4978	Transcriptional regulator
N1207_13185	COG0508	dehydrogenase complex catalyzes the overall conversion of
N1207_13190	COG0022	dehydrogenase e1 component
N1207_13195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N1207_13200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N1207_13205	COG3426	butyrate kinase activity
N1207_13210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N1207_13215	COG0280	phosphate acetyltransferase
N1207_13220	COG3829	transcription factor binding
N1207_13220	COG3290	protein histidine kinase activity
N1207_13230	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N1207_13235	COG2079	MmgE PrpD family protein
N1207_13240	COG0372	Belongs to the citrate synthase family
N1207_13245	COG1960	acyl-CoA dehydrogenase activity
N1207_13250	COG1250	3-hydroxyacyl-CoA dehydrogenase
N1207_13255	COG0183	Belongs to the thiolase family
N1207_13260	COG0584	glycerophosphoryl diester phosphodiesterase
N1207_13265	COG0860	N-Acetylmuramoyl-L-alanine amidase
N1207_13280	COG1902	pentaerythritol trinitrate reductase activity
N1207_13285	COG0745	RESPONSE REGULATOR receiver
N1207_13290	COG0750	zinc metalloprotease
N1207_13295	COG0497	DNA recombination
N1207_13300	COG1438	arginine binding
N1207_13305	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
N1207_13310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N1207_13315	COG0142	geranyltranstransferase activity
N1207_13320	COG1722	exodeoxyribonuclease VII activity
N1207_13325	COG1570	exodeoxyribonuclease VII activity
N1207_13330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N1207_13335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N1207_13340	COG1302	Protein conserved in bacteria
N1207_13345	COG0439	Biotin carboxylase
N1207_13350	COG0511	ligase activity, forming carbon-carbon bonds
N1207_13390	COG3854	ATPases associated with a variety of cellular activities
N1207_13400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N1207_13405	COG0006	proline dipeptidase activity
N1207_13410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N1207_13420	COG3872	metal-dependent enzyme
N1207_13430	COG1752	Esterase of the alpha-beta hydrolase superfamily
N1207_13435	COG1321	iron dependent repressor
N1207_13440	COG0095	Lipoate-protein ligase
N1207_13445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N1207_13450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N1207_13455	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N1207_13460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N1207_13465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N1207_13480	COG1396	sequence-specific DNA binding
N1207_13490	COG0681	Belongs to the peptidase S26 family
N1207_13515	COG4940	Competence protein ComGF
N1207_13525	COG4970	Tfp pilus assembly protein FimT
N1207_13530	COG4537	Required for transformation and DNA binding
N1207_13535	COG1459	type II secretion system
N1207_13540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N1207_13545	COG0598	Magnesium transport protein CorA
N1207_13550	COG1253	flavin adenine dinucleotide binding
N1207_13555	COG1366	Belongs to the anti-sigma-factor antagonist family
N1207_13565	COG1393	Belongs to the ArsC family
N1207_13575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N1207_13585	COG0011	TIGRFAM Protein of
N1207_13595	COG2866	Carboxypeptidase
N1207_13600	COG1368	sulfuric ester hydrolase activity
N1207_13605	COG1940	carbohydrate kinase activity
N1207_13610	COG4483	Protein conserved in bacteria
N1207_13615	COG0705	Rhomboid family
N1207_13615	COG0457	Tetratricopeptide repeat
N1207_13625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N1207_13635	COG0438	transferase activity, transferring glycosyl groups
N1207_13650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N1207_13655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N1207_13660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N1207_13665	COG0581	inorganic phosphate transmembrane transporter activity
N1207_13670	COG0573	inorganic phosphate transmembrane transporter activity
N1207_13675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N1207_13680	COG0768	penicillin binding
N1207_13685	COG0477	Major facilitator Superfamily
N1207_13690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N1207_13695	COG2839	Protein conserved in bacteria
N1207_13700	COG5521	maltodextrose utilization protein MalA
N1207_13705	COG1388	LysM domain
N1207_13710	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N1207_13715	COG4709	membrane
N1207_13720	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
N1207_13725	COG0735	belongs to the Fur family
N1207_13730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N1207_13740	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N1207_13745	COG0513	Belongs to the DEAD box helicase family
N1207_13755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N1207_13760	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N1207_13765	COG2384	SAM-dependent methyltransferase
N1207_13770	COG2010	Cytochrome c
N1207_13775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N1207_13780	COG0358	DNA primase activity
N1207_13785	COG1671	Belongs to the UPF0178 family
N1207_13790	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N1207_13795	COG0517	IMP dehydrogenase activity
N1207_13800	COG0751	glycine-tRNA ligase activity
N1207_13805	COG0752	glycyl-tRNA synthetase alpha subunit
N1207_13810	COG1381	Involved in DNA repair and RecF pathway recombination
N1207_13820	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N1207_13825	COG0295	cytidine deaminase activity
N1207_13830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N1207_13835	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N1207_13840	COG1480	7TM receptor with intracellular HD hydrolase
N1207_13845	COG1702	phosphate starvation-inducible protein PhoH
N1207_13850	COG0561	phosphatase activity
N1207_13865	COG4864	UPF0365 protein
N1207_13870	COG1030	water channel activity
N1207_13875	COG1610	YqeY-like protein
N1207_13885	COG1283	sodium-dependent phosphate transmembrane transporter activity
N1207_13890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N1207_13895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N1207_13900	COG2264	protein methyltransferase activity
N1207_13905	COG0484	heat shock protein binding
N1207_13910	COG0443	Heat shock 70 kDa protein
N1207_13915	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N1207_13920	COG1420	regulation of RNA biosynthetic process
N1207_13925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N1207_13930	COG0481	GTPase activity
N1207_13940	COG0860	N-Acetylmuramoyl-L-alanine amidase
N1207_13945	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
N1207_13955	COG1466	dna polymerase III delta subunit
N1207_13970	COG2333	competence protein COMEC
N1207_13970	COG0658	competence protein
N1207_13975	COG2131	deaminase
N1207_13980	COG1596	polysaccharide export
N1207_13980	COG1555	photosystem II stabilization
N1207_13985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N1207_13990	COG2226	methyltransferase
N1207_13995	COG0799	negative regulation of ribosome biogenesis
N1207_14000	COG1713	HD superfamily hydrolase involved in NAD metabolism
N1207_14005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N1207_14010	COG1534	Rna-binding protein
N1207_14015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N1207_14020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N1207_14025	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
N1207_14035	COG2755	lipolytic protein G-D-S-L family
N1207_14040	COG5632	N-Acetylmuramoyl-L-alanine amidase
N1207_14040	COG3409	Peptidoglycan-binding domain 1 protein
N1207_14045	COG0398	Pfam SNARE associated Golgi protein
N1207_14050	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
N1207_14060	COG3209	COG3209 Rhs family protein
N1207_14070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N1207_14080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N1207_14085	COG0798	PFAM Bile acid sodium symporter
N1207_14090	COG0346	lactoylglutathione lyase activity
N1207_14095	COG0640	Transcriptional regulator
N1207_14100	COG3403	YqcI/YcgG family
N1207_14105	COG0457	Tetratricopeptide repeat
N1207_14120	COG5444	nuclease activity
N1207_14145	COG3409	Peptidoglycan-binding domain 1 protein
N1207_14145	COG5632	N-Acetylmuramoyl-L-alanine amidase
N1207_14150	COG4824	toxin secretion phage lysis holin
N1207_14180	COG3778	Protein conserved in bacteria
N1207_14185	COG3299	homolog of phage Mu protein gp47
N1207_14190	COG3628	GPW Gp25 family protein
N1207_14200	COG4193	domain, Protein
N1207_14205	COG1652	LysM domain
N1207_14210	COG5280	Phage tail tape measure protein TP901
N1207_14210	COG3953	SLT domain
N1207_14275	COG4653	Phage capsid family
N1207_14280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N1207_14290	COG2369	cell adhesion
N1207_14295	COG5518	Phage portal protein
N1207_14300	COG1783	phage Terminase large subunit
N1207_14305	COG5484	DNA packaging
N1207_14315	COG3677	Transposase
N1207_14330	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
N1207_14340	COG1484	DNA-dependent DNA replication
N1207_14345	COG3935	DnaD domain protein
N1207_14350	COG3723	Recombinational DNA repair protein, rece pathway
N1207_14355	COG5377	YqaJ viral recombinase family
N1207_14385	COG1476	TRANSCRIPTIONal
N1207_14390	COG3620	sequence-specific DNA binding
N1207_14400	COG0563	adenylate kinase activity
N1207_14405	COG2856	Zn peptidase
N1207_14430	COG3223	Belongs to the PsiE family
N1207_14435	COG0642	Histidine kinase
N1207_14435	COG5002	protein histidine kinase activity
N1207_14440	COG0745	RESPONSE REGULATOR receiver
N1207_14445	COG2311	Membrane
N1207_14455	COG0454	-acetyltransferase
N1207_14460	COG2249	NAD(P)H dehydrogenase (quinone) activity
N1207_14470	COG0730	response to heat
N1207_14475	COG0425	Belongs to the sulfur carrier protein TusA family
N1207_14490	COG0425	Belongs to the sulfur carrier protein TusA family
N1207_14490	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N1207_14500	COG2210	Belongs to the sulfur carrier protein TusA family
N1207_14505	COG1937	Protein conserved in bacteria
N1207_14515	COG0662	Cupin 2, conserved barrel domain protein
N1207_14530	COG0789	Transcriptional regulator
N1207_14530	COG4978	Transcriptional regulator
N1207_14535	COG2814	Major facilitator Superfamily
N1207_14540	COG0456	acetyltransferase
N1207_14545	COG1253	flavin adenine dinucleotide binding
N1207_14555	COG0697	spore germination
N1207_14560	COG0583	DNA-binding transcription factor activity
N1207_14565	COG2072	flavoprotein involved in K transport
N1207_14570	COG1230	cation diffusion facilitator family transporter
N1207_14575	COG1942	4-Oxalocrotonate Tautomerase
N1207_14580	COG0583	DNA-binding transcription factor activity
N1207_14590	COG1114	Component of the transport system for branched-chain amino acids
N1207_14595	COG1687	branched-chain amino acid
N1207_14600	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N1207_14605	COG1522	sequence-specific DNA binding
N1207_14610	COG2732	(Barnase) inhibitor
N1207_14615	COG2124	cytochrome p450
N1207_14625	COG1335	isochorismatase
N1207_14640	COG2318	DinB family
N1207_14650	COG2070	2-Nitropropane dioxygenase
N1207_14655	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N1207_14665	COG2186	Transcriptional regulator
N1207_14680	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_14685	COG3958	Transketolase
N1207_14690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N1207_14695	COG0477	Major facilitator Superfamily
N1207_14700	COG1846	Transcriptional regulator
N1207_14705	COG3443	Belongs to the bacterial solute-binding protein 9 family
N1207_14710	COG1595	DNA-templated transcription, initiation
N1207_14715	COG0667	Aldo Keto reductase
N1207_14720	COG2851	Citrate transporter
N1207_14725	COG0583	DNA-binding transcription factor activity
N1207_14730	COG2828	Protein conserved in bacteria
N1207_14735	COG3409	Peptidoglycan-binding domain 1 protein
N1207_14740	COG5566	PFAM Mor transcription activator
N1207_14745	COG0596	Alpha beta hydrolase
N1207_14750	COG4991	sh3 domain protein
N1207_14755	COG4991	sh3 domain protein
N1207_14765	COG0346	lactoylglutathione lyase activity
N1207_14775	COG5577	PFAM Coat F domain
N1207_14780	COG1063	alcohol dehydrogenase
N1207_14790	COG5577	PFAM Coat F domain
N1207_14795	COG0789	Transcriptional regulator
N1207_14805	COG1064	alcohol dehydrogenase
N1207_14810	COG0693	protein deglycase activity
N1207_14815	COG1621	beta-fructofuranosidase activity
N1207_14825	COG3716	PTS system mannose fructose sorbose family IID component
N1207_14830	COG3715	PTS system
N1207_14835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_14840	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
N1207_14845	COG3933	PFAM sigma-54 factor interaction domain-containing protein
N1207_14845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N1207_14855	COG1113	amino acid transport
N1207_14860	COG1280	lysine exporter protein (LysE YggA)
N1207_14865	COG1378	Sugar-specific transcriptional regulator TrmB
N1207_14870	COG1595	DNA-templated transcription, initiation
N1207_14880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N1207_14880	COG2755	lipolytic protein G-D-S-L family
N1207_14890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N1207_14890	COG2124	cytochrome p450
N1207_14895	COG1309	transcriptional regulator
N1207_14900	COG2226	methyltransferase
N1207_14915	COG2116	formate transmembrane transporter activity
N1207_14920	COG5609	conserved protein (DUF2294)
N1207_14925	COG3383	formate dehydrogenase (NAD+) activity
N1207_14930	COG2427	Protein of unknown function (DUF1641)
N1207_14940	COG0626	cystathionine gamma-synthase activity
N1207_14945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N1207_14950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N1207_14955	COG2226	methyltransferase
N1207_14970	COG0768	penicillin binding
N1207_14975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N1207_14980	COG0572	uridine kinase
N1207_14985	COG0826	peptidase U32
N1207_14990	COG0826	peptidase U32
N1207_14995	COG4122	O-methyltransferase activity
N1207_15000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N1207_15005	COG3906	Belongs to the UPF0473 family
N1207_15010	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N1207_15015	COG4472	Bacterial protein of unknown function (DUF965)
N1207_15020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N1207_15025	COG0628	permease
N1207_15030	COG1126	abc transporter atp-binding protein
N1207_15035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N1207_15040	COG0765	amino acid transport
N1207_15045	COG0765	amino acid transport
N1207_15060	COG3881	PFAM PRC-barrel domain
N1207_15065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N1207_15070	COG0457	Tetratricopeptide repeat
N1207_15075	COG0482	sulfurtransferase activity
N1207_15080	COG1104	cysteine desulfurase activity
N1207_15085	COG1959	2 iron, 2 sulfur cluster binding
N1207_15090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N1207_15095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N1207_15105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N1207_15110	COG0124	histidyl-tRNA synthetase
N1207_15120	COG0860	N-Acetylmuramoyl-L-alanine amidase
N1207_15120	COG3103	Sh3 type 3 domain protein
N1207_15120	COG4991	sh3 domain protein
N1207_15125	COG1490	D-aminoacyl-tRNA deacylase activity
N1207_15130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N1207_15135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N1207_15140	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
N1207_15140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N1207_15145	COG5416	Lipopolysaccharide assembly protein A domain
N1207_15150	COG0490	domain, Protein
N1207_15155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N1207_15155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N1207_15165	COG2244	polysaccharide biosynthetic process
N1207_15170	COG2323	membrane
N1207_15180	COG1862	Preprotein translocase
N1207_15185	COG0343	queuine tRNA-ribosyltransferase activity
N1207_15190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N1207_15200	COG2255	four-way junction helicase activity
N1207_15205	COG0632	four-way junction helicase activity
N1207_15215	COG2814	Major facilitator Superfamily
N1207_15220	COG0673	inositol 2-dehydrogenase activity
N1207_15225	COG2112	serine threonine protein kinase
N1207_15245	COG1115	amino acid carrier protein
N1207_15250	COG0217	transcriptional regulatory protein
N1207_15260	COG1388	LysM domain
N1207_15265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N1207_15270	COG0157	Belongs to the NadC ModD family
N1207_15275	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N1207_15280	COG1104	cysteine desulfurase activity
N1207_15285	COG1827	regulation of RNA biosynthetic process
N1207_15290	COG0077	Prephenate dehydratase
N1207_15295	COG4492	Belongs to the UPF0735 family
N1207_15300	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N1207_15305	COG3290	protein histidine kinase activity
N1207_15315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N1207_15320	COG2868	ribosomal protein
N1207_15325	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N1207_15330	COG1994	Peptidase M50
N1207_15335	COG0739	heme binding
N1207_15340	COG2894	cell division
N1207_15345	COG0850	regulation of cytokinetic process
N1207_15350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N1207_15360	COG1077	Cell shape determining protein MreB Mrl
N1207_15365	COG2003	Belongs to the UPF0758 family
N1207_15370	COG0424	maF-like protein
N1207_15380	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
N1207_15385	COG0285	dihydrofolate synthase activity
N1207_15390	COG0525	valine-tRNA ligase activity
N1207_15400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N1207_15405	COG1388	LysM domain
N1207_15410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N1207_15415	COG0113	porphobilinogen synthase activity
N1207_15420	COG1587	Uroporphyrinogen-III synthase
N1207_15425	COG0181	hydroxymethylbilane synthase activity
N1207_15430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N1207_15435	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N1207_15445	COG0218	Necessary for normal cell division and for the maintenance of normal septation
N1207_15450	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N1207_15455	COG0470	DNA polymerase III
N1207_15455	COG1067	ATP-dependent peptidase activity
N1207_15460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N1207_15465	COG0544	peptidyl-prolyl cis-trans isomerase activity
N1207_15470	COG1477	protein flavinylation
N1207_15470	COG0457	Tetratricopeptide repeat
N1207_15475	COG0066	3-isopropylmalate dehydratase activity
N1207_15480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N1207_15485	COG0473	3-isopropylmalate dehydrogenase activity
N1207_15490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N1207_15495	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N1207_15500	COG0440	acetolactate synthase activity
N1207_15505	COG0028	Belongs to the TPP enzyme family
N1207_15515	COG0454	-acetyltransferase
N1207_15520	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
N1207_15530	COG0622	Phosphoesterase
N1207_15535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N1207_15540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N1207_15545	COG5401	PFAM Sporulation and spore germination
N1207_15550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N1207_15555	COG1846	Transcriptional regulator
N1207_15560	COG2197	response regulator
N1207_15565	COG0824	Thioesterase
N1207_15570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N1207_15575	COG1053	succinate dehydrogenase
N1207_15580	COG2009	succinate dehydrogenase
N1207_15585	COG1719	4-vinyl reductase, 4VR
N1207_15590	COG0527	aspartate kinase activity
N1207_15595	COG0322	excinuclease ABC activity
N1207_15600	COG3118	belongs to the thioredoxin family
N1207_15605	COG3534	alpha-L-arabinofuranosidase
N1207_15610	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N1207_15615	COG2086	electron transfer activity
N1207_15620	COG1024	Enoyl-CoA hydratase
N1207_15625	COG1309	transcriptional regulator
N1207_15630	COG0318	PFAM AMP-dependent synthetase and ligase
N1207_15635	COG3766	membrane
N1207_15640	COG1193	negative regulation of DNA recombination
N1207_15645	COG1796	DNA polymerase
N1207_15645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N1207_15650	COG1286	toxin biosynthetic process
N1207_15655	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
N1207_15660	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N1207_15665	COG0072	phenylalanine-tRNA ligase activity
N1207_15665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N1207_15670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N1207_15680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N1207_15690	COG3835	regulator
N1207_15695	COG0277	FAD linked oxidase domain protein
N1207_15700	COG0247	lactate metabolic process
N1207_15705	COG0346	lactoylglutathione lyase activity
N1207_15715	COG1966	Carbon starvation protein
N1207_15720	COG3534	alpha-L-arabinofuranosidase
N1207_15725	COG0395	ABC-type sugar transport system, permease component
N1207_15730	COG1175	transmembrane transport
N1207_15735	COG1653	transport
N1207_15740	COG0371	Dehydrogenase
N1207_15745	COG0647	UMP catabolic process
N1207_15750	COG0235	Class ii aldolase
N1207_15755	COG1069	ribulokinase activity
N1207_15760	COG2160	L-arabinose isomerase activity
N1207_15765	COG3507	Belongs to the glycosyl hydrolase 43 family
N1207_15770	COG1363	Peptidase, m42
N1207_15780	COG3326	Membrane
N1207_15785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N1207_15790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N1207_15795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N1207_15805	COG1346	cytolysis
N1207_15810	COG1380	Effector of murein hydrolase LrgA
N1207_15815	COG3279	Response regulator of the LytR AlgR family
N1207_15820	COG3275	phosphorelay sensor kinase activity
N1207_15825	COG1011	Hydrolase
N1207_15830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N1207_15840	COG0398	Pfam SNARE associated Golgi protein
N1207_15845	COG1484	DNA-dependent DNA replication
N1207_15850	COG3611	Membrane attachment protein
N1207_15855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N1207_15860	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
N1207_15865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N1207_15870	COG1733	regulation of RNA biosynthetic process
N1207_15875	COG2814	Major facilitator Superfamily
N1207_15880	COG0656	L-ascorbic acid biosynthetic process
N1207_15885	COG0237	dephospho-CoA kinase activity
N1207_15895	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N1207_15900	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N1207_15900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N1207_15905	COG5002	protein histidine kinase activity
N1207_15910	COG0745	RESPONSE REGULATOR receiver
N1207_15915	COG0039	L-malate dehydrogenase activity
N1207_15920	COG0538	isocitrate dehydrogenase activity
N1207_15925	COG0372	Belongs to the citrate synthase family
N1207_15930	COG2707	UPF0756 membrane protein
N1207_15935	COG0628	permease
N1207_15940	COG3030	protein affecting phage T7 exclusion by the F plasmid
N1207_15945	COG0469	pyruvate kinase activity
N1207_15950	COG0205	6-phosphofructokinase activity
N1207_15955	COG0825	malonyl-CoA metabolic process
N1207_15960	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N1207_15965	COG0281	malic enzyme
N1207_15970	COG0587	DNA-directed DNA polymerase activity
N1207_15990	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N1207_16000	COG4109	DRTGG domain
N1207_16005	COG0730	response to heat
N1207_16010	COG1473	amidohydrolase
N1207_16015	COG0196	riboflavin kinase activity
N1207_16020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N1207_16025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N1207_16030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N1207_16035	COG1126	abc transporter atp-binding protein
N1207_16040	COG0765	amino acid transport
N1207_16045	COG0765	amino acid transport
N1207_16050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N1207_16055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N1207_16060	COG0454	-acetyltransferase
N1207_16065	COG0583	DNA-binding transcription factor activity
N1207_16070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N1207_16075	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_16085	COG0165	Argininosuccinate lyase
N1207_16090	COG0137	argininosuccinate synthase activity
N1207_16095	COG0521	Mo-molybdopterin cofactor biosynthetic process
N1207_16100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N1207_16110	COG0827	DNA restriction-modification system
N1207_16115	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
N1207_16120	COG3874	Sporulation protein YtfJ
N1207_16130	COG1714	RDD family
N1207_16135	COG0616	signal peptide processing
N1207_16140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N1207_16145	COG1574	metal-dependent hydrolase with the TIM-barrel fold
N1207_16150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N1207_16160	COG0301	tRNA thio-modification
N1207_16165	COG1104	cysteine desulfurase activity
N1207_16170	COG1114	Component of the transport system for branched-chain amino acids
N1207_16175	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
N1207_16180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N1207_16185	COG1309	transcriptional regulator
N1207_16190	COG1956	GAF domain-containing protein
N1207_16195	COG2203	Gaf domain
N1207_16195	COG2199	diguanylate cyclase activity
N1207_16200	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N1207_16210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N1207_16215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N1207_16220	COG0454	-acetyltransferase
N1207_16225	COG0517	IMP dehydrogenase activity
N1207_16230	COG0123	including yeast histone deacetylase and acetoin utilization protein
N1207_16235	COG1360	Flagellar Motor Protein
N1207_16240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N1207_16245	COG1609	Transcriptional regulator
N1207_16250	COG1605	Chorismate mutase
N1207_16250	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
N1207_16255	COG3118	belongs to the thioredoxin family
N1207_16260	COG4980	gas vesicle protein
N1207_16265	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N1207_16270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N1207_16275	COG1674	ftsk spoiiie
N1207_16280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N1207_16285	COG4848	Belongs to the UPF0354 family
N1207_16290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N1207_16305	COG1363	Peptidase, m42
N1207_16310	COG5584	Small secreted protein
N1207_16315	COG0281	malic enzyme
N1207_16320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N1207_16325	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N1207_16335	COG0510	thiamine kinase activity
N1207_16340	COG1523	belongs to the glycosyl hydrolase 13 family
N1207_16345	COG1597	lipid kinase activity
N1207_16355	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N1207_16360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N1207_16365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N1207_16370	COG2252	PERMEase
N1207_16375	COG4473	ABC transporter
N1207_16380	COG1131	(ABC) transporter
N1207_16385	COG1349	DNA-binding transcription factor activity
N1207_16390	COG1187	pseudouridine synthase activity
N1207_16395	COG2244	polysaccharide biosynthetic process
N1207_16400	COG2081	HI0933 family
N1207_16405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N1207_16415	COG5578	integral membrane protein
N1207_16420	COG0673	inositol 2-dehydrogenase activity
N1207_16425	COG1653	transport
N1207_16430	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N1207_16435	COG4209	transmembrane transport
N1207_16440	COG2207	Transcriptional regulator
N1207_16445	COG1653	transport
N1207_16450	COG0395	ABC-type sugar transport system, permease component
N1207_16455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N1207_16460	COG2124	cytochrome p450
N1207_16465	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N1207_16475	COG0156	8-amino-7-oxononanoate synthase activity
N1207_16480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N1207_16490	COG1073	alpha beta
N1207_16495	COG1609	Transcriptional regulator
N1207_16500	COG1653	transport
N1207_16505	COG1175	transmembrane transport
N1207_16510	COG0395	ABC-type sugar transport system, permease component
N1207_16515	COG1486	melibiose metabolic process
N1207_16520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N1207_16525	COG0495	leucyl-tRNA aminoacylation
N1207_16535	COG1366	Belongs to the anti-sigma-factor antagonist family
N1207_16535	COG2202	Pas domain
N1207_16540	COG2814	Major facilitator Superfamily
N1207_16545	COG2433	Pfam Transposase IS66
N1207_16550	COG0577	efflux transmembrane transporter activity
N1207_16555	COG1136	(ABC) transporter
N1207_16560	COG2205	protein histidine kinase activity
N1207_16565	COG0745	RESPONSE REGULATOR receiver
N1207_16570	COG0577	efflux transmembrane transporter activity
N1207_16575	COG1136	(ABC) transporter
N1207_16590	COG1131	(ABC) transporter
N1207_16595	COG1725	Transcriptional regulator
N1207_16610	COG1242	4 iron, 4 sulfur cluster binding
N1207_16615	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
N1207_16625	COG2267	carboxylic ester hydrolase activity
N1207_16630	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N1207_16635	COG1113	amino acid transport
N1207_16640	COG0367	asparagine synthase
N1207_16645	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N1207_16650	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N1207_16660	COG1506	peptidase
N1207_16665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N1207_16670	COG1116	anion transmembrane transporter activity
N1207_16675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N1207_16680	COG0494	nUDIX hydrolase
N1207_16685	COG4824	toxin secretion phage lysis holin
N1207_16690	COG0783	Belongs to the Dps family
N1207_16705	COG1854	S-ribosylhomocysteine lyase activity
N1207_16710	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N1207_16715	COG0288	reversible hydration of carbon dioxide
N1207_16720	COG0254	rRNA binding
N1207_16725	COG1271	oxidase subunit
N1207_16730	COG1294	oxidase, subunit
N1207_16740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N1207_16745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N1207_16745	COG1321	iron dependent repressor
N1207_16750	COG1121	(ABC) transporter
N1207_16755	COG0803	Belongs to the bacterial solute-binding protein 9 family
N1207_16760	COG4948	Mandelate Racemase Muconate Lactonizing
N1207_16765	COG0318	PFAM AMP-dependent synthetase and ligase
N1207_16770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
N1207_16775	COG0596	Alpha beta hydrolase
N1207_16780	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N1207_16785	COG1169	isochorismate synthase
N1207_16790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N1207_16795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N1207_16800	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N1207_16805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N1207_16810	COG0438	transferase activity, transferring glycosyl groups
N1207_16820	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N1207_16825	COG0438	transferase activity, transferring glycosyl groups
N1207_16830	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N1207_16835	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
N1207_16840	COG0058	SHG alpha-glucan phosphorylase activity
N1207_16845	COG0297	glycogen (starch) synthase activity
N1207_16850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N1207_16855	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N1207_16860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N1207_16985	COG3859	Proton-coupled thiamine transporter YuaJ
N1207_16990	COG1247	-acetyltransferase
N1207_16995	COG2268	Band 7 protein
N1207_17000	COG1585	Membrane protein implicated in regulation of membrane protease activity
N1207_17005	COG2318	DinB family
N1207_17015	COG1454	alcohol dehydrogenase
N1207_17020	COG1012	belongs to the aldehyde dehydrogenase family
N1207_17025	COG1510	regulation of RNA biosynthetic process
N1207_17035	COG0569	domain protein
N1207_17040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N1207_17045	COG4682	membrane
N1207_17050	COG1705	Flagellar rod assembly protein muramidase FlgJ
N1207_17055	COG0477	Major facilitator Superfamily
N1207_17060	COG5553	Cysteine dioxygenase type I
N1207_17070	COG1968	undecaprenyl-diphosphatase activity
N1207_17075	COG0628	permease
N1207_17080	COG0673	inositol 2-dehydrogenase activity
N1207_17085	COG4806	L-rhamnose isomerase
N1207_17090	COG3254	rhamnose metabolic process
N1207_17095	COG1070	Carbohydrate kinase
N1207_17100	COG1349	DNA-binding transcription factor activity
N1207_17105	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_17105	COG3347	Dehydrogenase
N1207_17110	COG0840	transmembrane signaling receptor activity
N1207_17115	COG0840	transmembrane signaling receptor activity
N1207_17120	COG0840	transmembrane signaling receptor activity
N1207_17125	COG0840	transmembrane signaling receptor activity
N1207_17140	COG0432	Pfam Uncharacterised protein family UPF0047
N1207_17150	COG0366	Alpha amylase catalytic
N1207_17155	COG1253	flavin adenine dinucleotide binding
N1207_17160	COG2738	Putative neutral zinc metallopeptidase
N1207_17175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N1207_17190	COG0166	Belongs to the GPI family
N1207_17195	COG1979	alcohol dehydrogenase
N1207_17200	COG1979	alcohol dehydrogenase
N1207_17205	COG2155	Conserved Protein
N1207_17210	COG1098	S1 RNA binding domain
N1207_17215	COG0436	Aminotransferase
N1207_17220	COG1522	sequence-specific DNA binding
N1207_17225	COG2267	carboxylic ester hydrolase activity
N1207_17235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
N1207_17240	COG2205	protein histidine kinase activity
N1207_17250	COG5018	Exonuclease
N1207_17260	COG2814	Major facilitator Superfamily
N1207_17265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N1207_17270	COG3011	Protein conserved in bacteria
N1207_17280	COG3290	protein histidine kinase activity
N1207_17285	COG4565	transcriptional regulatory protein
N1207_17290	COG1744	ABC transporter substrate-binding protein PnrA-like
N1207_17295	COG3845	ABC transporter
N1207_17300	COG4603	Belongs to the binding-protein-dependent transport system permease family
N1207_17305	COG1079	Belongs to the binding-protein-dependent transport system permease family
N1207_17310	COG3493	citrate carrier protein
N1207_17320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N1207_17320	COG2111	Na H antiporter
N1207_17325	COG2111	Na H antiporter
N1207_17330	COG1006	Multisubunit Na H antiporter MnhC subunit
N1207_17335	COG0651	ATP synthesis coupled electron transport
N1207_17340	COG1863	multisubunit Na H antiporter MnhE subunit
N1207_17345	COG2212	antiporter activity
N1207_17350	COG1320	monovalent cation:proton antiporter activity
N1207_17355	COG2050	protein possibly involved in aromatic compounds catabolism
N1207_17360	COG2197	response regulator
N1207_17365	COG4585	Histidine kinase
N1207_17375	COG0142	geranyltranstransferase activity
N1207_17395	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N1207_17400	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N1207_17405	COG1335	isochorismatase
N1207_17410	COG5506	Protein of unknown function (DUF1694)
N1207_17425	COG0628	permease
N1207_17440	COG1418	mRNA catabolic process
N1207_17445	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_17455	COG1511	domain protein
N1207_17460	COG0433	COG0433 Predicted ATPase
N1207_17460	COG1674	ftsk spoiiie
N1207_17465	COG4499	WXG100 protein secretion system (Wss), protein YukC
N1207_17470	COG5417	Belongs to the EsaB family
N1207_17475	COG4842	Belongs to the WXG100 family
N1207_17480	COG2508	Transcriptional regulator
N1207_17480	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N1207_17485	COG0686	Belongs to the AlaDH PNT family
N1207_17490	COG5634	Uncharacterized conserved protein (DUF2278)
N1207_17495	COG3251	PFAM MbtH domain protein
N1207_17500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_17505	COG1535	isochorismatase
N1207_17505	COG3433	isochorismatase activity
N1207_17510	COG1021	2,3-dihydroxybenzoate-AMP ligase
N1207_17515	COG1169	isochorismate synthase
N1207_17520	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_17525	COG2819	hydrolase of the alpha beta superfamily
N1207_17530	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N1207_17535	COG1268	BioY protein
N1207_17540	COG2056	Na+-H+ antiporter family
N1207_17545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N1207_17550	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
N1207_17555	COG3584	3D domain protein
N1207_17570	COG1252	NADH dehydrogenase
N1207_17575	COG0492	ferredoxin-NADP+ reductase activity
N1207_17585	COG0516	GMP reductase activity
N1207_17590	COG2808	Putative FMN-binding domain
N1207_17595	COG0456	acetyltransferase
N1207_17600	COG0316	Belongs to the HesB IscA family
N1207_17605	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N1207_17610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N1207_17615	COG4844	belongs to the
N1207_17620	COG1252	NADH dehydrogenase
N1207_17625	COG4837	Protein of unknown function (DUF1462)
N1207_17630	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N1207_17635	COG0823	Involved in the tonB-independent uptake of proteins
N1207_17635	COG1506	peptidase
N1207_17635	COG4946	Tricorn protease homolog
N1207_17640	COG0083	homoserine kinase activity
N1207_17645	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N1207_17650	COG0460	homoserine dehydrogenase
N1207_17655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N1207_17660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N1207_17665	COG0647	UMP catabolic process
N1207_17670	COG2445	Protein of unknown function DUF86
N1207_17675	COG4470	Protein conserved in bacteria
N1207_17685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N1207_17690	COG0739	heme binding
N1207_17700	COG3377	Domain of unknown function (DUF1805)
N1207_17705	COG0737	Belongs to the 5'-nucleotidase family
N1207_17710	COG0730	response to heat
N1207_17715	COG1801	Protein of unknown function DUF72
N1207_17725	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N1207_17730	COG2508	Transcriptional regulator
N1207_17735	COG2233	PERMEase
N1207_17740	COG2233	PERMEase
N1207_17745	COG3195	allantoin biosynthetic process
N1207_17745	COG3648	Uricase
N1207_17750	COG2351	hydroxyisourate hydrolase activity
N1207_17760	COG2080	2 iron, 2 sulfur cluster binding
N1207_17765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N1207_17770	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
N1207_17775	COG2068	MobA-Related Protein
N1207_17780	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N1207_17785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N1207_17790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N1207_17800	COG2356	endonuclease I
N1207_17805	COG3842	ATPase activity
N1207_17810	COG2188	Transcriptional regulator
N1207_17815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N1207_17820	COG0395	ABC-type sugar transport system, permease component
N1207_17825	COG1175	transmembrane transport
N1207_17830	COG1653	transport
N1207_17835	COG2222	sugar isomerase
N1207_17840	COG0322	excinuclease ABC activity
N1207_17845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N1207_17860	COG0346	lactoylglutathione lyase activity
N1207_17865	COG0640	Transcriptional regulator
N1207_17870	COG0719	Fe-S assembly protein
N1207_17875	COG0822	iron-sulfur transferase activity
N1207_17880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N1207_17885	COG0719	Fe-S assembly protein
N1207_17890	COG0396	ATPase activity
N1207_17900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N1207_17905	COG1464	Belongs to the NlpA lipoprotein family
N1207_17910	COG2011	ABC-type metal ion transport system permease component
N1207_17915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N1207_17925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N1207_17930	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N1207_17940	COG0509	glycine decarboxylation via glycine cleavage system
N1207_17945	COG1393	Belongs to the ArsC family
N1207_17950	COG1960	acyl-CoA dehydrogenase activity
N1207_17955	COG0183	Belongs to the thiolase family
N1207_17960	COG1250	3-hydroxyacyl-CoA dehydrogenase
N1207_17960	COG1024	Enoyl-CoA hydratase
N1207_17970	COG0506	proline dehydrogenase activity
N1207_17980	COG5577	PFAM Coat F domain
N1207_17985	COG1846	Transcriptional regulator
N1207_17990	COG0477	Major facilitator Superfamily
N1207_17995	COG1942	4-Oxalocrotonate Tautomerase
N1207_18005	COG0583	DNA-binding transcription factor activity
N1207_18015	COG1120	ATPase activity
N1207_18030	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_18035	COG0783	Belongs to the Dps family
N1207_18040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N1207_18045	COG0745	RESPONSE REGULATOR receiver
N1207_18050	COG2205	protein histidine kinase activity
N1207_18050	COG2770	Histidine kinase
N1207_18060	COG1309	transcriptional regulator
N1207_18065	COG0114	fumarate hydratase activity
N1207_18075	COG0697	spore germination
N1207_18080	COG0814	amino acid
N1207_18090	COG2197	response regulator
N1207_18095	COG4585	Histidine kinase
N1207_18100	COG4758	membrane
N1207_18105	COG3595	metallopeptidase activity
N1207_18110	COG1842	Phage shock protein A
N1207_18115	COG4758	membrane
N1207_18120	COG2814	Major facilitator Superfamily
N1207_18125	COG2096	Adenosyltransferase
N1207_18130	COG1120	ATPase activity
N1207_18135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N1207_18140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N1207_18145	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_18150	COG3386	PFAM SMP-30 Gluconolaconase
N1207_18155	COG2205	protein histidine kinase activity
N1207_18160	COG0745	RESPONSE REGULATOR receiver
N1207_18170	COG1191	sigma factor activity
N1207_18180	COG2140	Oxalate decarboxylase
N1207_18190	COG0577	efflux transmembrane transporter activity
N1207_18195	COG1136	(ABC) transporter
N1207_18200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N1207_18205	COG1120	ATPase activity
N1207_18210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N1207_18215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N1207_18220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N1207_18225	COG0531	amino acid
N1207_18235	COG1988	membrane-bound metal-dependent
N1207_18240	COG1368	sulfuric ester hydrolase activity
N1207_18245	COG1910	domain protein
N1207_18250	COG0725	ABC transporter, periplasmic molybdate-binding protein
N1207_18255	COG4149	molybdate abc transporter
N1207_18260	COG0656	L-ascorbic acid biosynthetic process
N1207_18270	COG0025	NhaP-type Na H and K H
N1207_18275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N1207_18280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N1207_18285	COG3973	AAA domain
N1207_18295	COG2860	membrane
N1207_18300	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
N1207_18305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N1207_18310	COG2217	Heavy metal translocating P-type atpase
N1207_18315	COG2217	Heavy metal translocating P-type atpase
N1207_18320	COG2608	mercury ion transmembrane transporter activity
N1207_18325	COG1937	Protein conserved in bacteria
N1207_18330	COG0673	inositol 2-dehydrogenase activity
N1207_18335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N1207_18340	COG1289	transmembrane transporter activity
N1207_18350	COG2076	Multidrug Resistance protein
N1207_18355	COG1309	transcriptional regulator
N1207_18360	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_18385	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N1207_18390	COG0557	exoribonuclease II activity
N1207_18395	COG1647	Serine aminopeptidase, S33
N1207_18400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N1207_18405	COG0596	Alpha beta hydrolase
N1207_18410	COG1476	TRANSCRIPTIONal
N1207_18415	COG1396	sequence-specific DNA binding
N1207_18420	COG1396	sequence-specific DNA binding
N1207_18425	COG1733	regulation of RNA biosynthetic process
N1207_18430	COG0840	transmembrane signaling receptor activity
N1207_18455	COG1131	(ABC) transporter
N1207_18485	COG1174	glycine betaine transport
N1207_18490	COG1732	Glycine betaine
N1207_18495	COG1174	glycine betaine transport
N1207_18500	COG0517	IMP dehydrogenase activity
N1207_18500	COG1125	glycine betaine transport
N1207_18505	COG1510	regulation of RNA biosynthetic process
N1207_18510	COG1174	glycine betaine transport
N1207_18515	COG1732	Glycine betaine
N1207_18520	COG1174	glycine betaine transport
N1207_18525	COG0517	IMP dehydrogenase activity
N1207_18525	COG1125	glycine betaine transport
N1207_18530	COG1510	regulation of RNA biosynthetic process
N1207_18535	COG2095	MarC family integral membrane protein
N1207_18545	COG3064	Membrane
N1207_18550	COG4640	response to antibiotic
N1207_18555	COG0456	acetyltransferase
N1207_18560	COG0148	phosphopyruvate hydratase activity
N1207_18565	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N1207_18570	COG0149	triose-phosphate isomerase activity
N1207_18575	COG0126	phosphoglycerate kinase activity
N1207_18580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N1207_18585	COG2390	Transcriptional regulator
N1207_18590	COG2814	Major facilitator Superfamily
N1207_18595	COG1609	Transcriptional regulator
N1207_18600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N1207_18605	COG0583	DNA-binding transcription factor activity
N1207_18610	COG0697	spore germination
N1207_18615	COG1113	amino acid transport
N1207_18620	COG3858	chitin binding
N1207_18625	COG1556	Lactate utilization protein
N1207_18630	COG1139	Iron-sulfur cluster binding protein
N1207_18635	COG0247	lactate metabolic process
N1207_18640	COG2197	response regulator
N1207_18645	COG4585	Histidine kinase
N1207_18650	COG0842	Transport permease protein
N1207_18655	COG1131	(ABC) transporter
N1207_18660	COG0596	Alpha beta hydrolase
N1207_18665	COG2208	phosphoserine phosphatase activity
N1207_18670	COG3867	Arabinogalactan endo-beta-1,4-galactanase
N1207_18675	COG1874	Beta-galactosidase
N1207_18680	COG3833	ABC-type maltose transport systems, permease component
N1207_18685	COG1175	transmembrane transport
N1207_18690	COG2182	Extracellular solute-binding protein
N1207_18695	COG1609	Transcriptional regulator
N1207_18700	COG2186	Transcriptional regulator
N1207_18705	COG1620	l-lactate permease
N1207_18710	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N1207_18715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N1207_18725	COG5039	Polysaccharide pyruvyl transferase
N1207_18730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N1207_18735	COG0110	maltose O-acetyltransferase activity
N1207_18740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N1207_18745	COG2244	polysaccharide biosynthetic process
N1207_18750	COG1216	Glycosyl transferase, family 2
N1207_18755	COG5039	Polysaccharide pyruvyl transferase
N1207_18760	COG1216	Glycosyl transferase, family 2
N1207_18770	COG0438	transferase activity, transferring glycosyl groups
N1207_18775	COG1215	transferase activity, transferring glycosyl groups
N1207_18780	COG0438	transferase activity, transferring glycosyl groups
N1207_18785	COG1086	Polysaccharide biosynthesis protein
N1207_18790	COG0489	protein tyrosine kinase activity
N1207_18800	COG1396	sequence-specific DNA binding
N1207_18805	COG2272	Belongs to the type-B carboxylesterase lipase family
N1207_18815	COG3479	Phenolic acid decarboxylase
N1207_18825	COG1794	racemase activity, acting on amino acids and derivatives
N1207_18830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N1207_18835	COG1621	beta-fructofuranosidase activity
N1207_18840	COG1621	beta-fructofuranosidase activity
N1207_18845	COG0531	amino acid
N1207_18850	COG1309	transcriptional regulator
N1207_18855	COG2076	Multidrug Resistance protein
N1207_18860	COG2076	Multidrug Resistance protein
N1207_18875	COG0740	serine-type endopeptidase activity
N1207_18880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N1207_18885	COG0366	Alpha amylase catalytic
N1207_18890	COG1554	hydrolase, family 65, central catalytic
N1207_18895	COG5521	maltodextrose utilization protein MalA
N1207_18900	COG3833	ABC-type maltose transport systems, permease component
N1207_18905	COG1175	transmembrane transport
N1207_18910	COG2182	Extracellular solute-binding protein
N1207_18915	COG0366	Alpha amylase catalytic
N1207_18920	COG1609	Transcriptional regulator
N1207_18925	COG1611	Belongs to the LOG family
N1207_18930	COG1694	Mazg nucleotide pyrophosphohydrolase
N1207_18935	COG0659	secondary active sulfate transmembrane transporter activity
N1207_18940	COG0288	reversible hydration of carbon dioxide
N1207_18945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N1207_18950	COG0577	efflux transmembrane transporter activity
N1207_18955	COG1136	(ABC) transporter
N1207_18960	COG5002	protein histidine kinase activity
N1207_18965	COG0745	RESPONSE REGULATOR receiver
N1207_18980	COG2162	N-hydroxyarylamine O-acetyltransferase activity
N1207_18985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N1207_18990	COG1481	regulation of sporulation
N1207_18995	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N1207_19000	COG1660	Displays ATPase and GTPase activities
N1207_19005	COG1051	belongs to the nudix hydrolase family
N1207_19010	COG0492	ferredoxin-NADP+ reductase activity
N1207_19015	COG0791	NLP P60 protein
N1207_19015	COG3883	PFAM NLP P60 protein
N1207_19020	COG0457	Tetratricopeptide repeat
N1207_19025	COG1132	(ABC) transporter
N1207_19045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N1207_19045	COG0140	phosphoribosyl-ATP diphosphatase activity
N1207_19050	COG0107	imidazoleglycerol-phosphate synthase activity
N1207_19055	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N1207_19060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N1207_19065	COG0131	Imidazoleglycerol-phosphate dehydratase
N1207_19070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N1207_19075	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N1207_19080	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
N1207_19085	COG4990	cell redox homeostasis
N1207_19090	COG5297	Belongs to the glycosyl hydrolase family 6
N1207_19095	COG0110	maltose O-acetyltransferase activity
N1207_19100	COG0546	phosphoglycolate phosphatase activity
N1207_19105	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
N1207_19110	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N1207_19115	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
N1207_19120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N1207_19125	COG0363	glucosamine-6-phosphate deaminase activity
N1207_19130	COG2188	Transcriptional regulator
N1207_19135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N1207_19140	COG1846	Transcriptional regulator
N1207_19155	COG1846	Transcriptional regulator
N1207_19160	COG2814	Major facilitator Superfamily
N1207_19165	COG1950	PFAM Membrane protein of
N1207_19170	COG1983	PspC domain protein
N1207_19175	COG3595	metallopeptidase activity
N1207_19195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N1207_19200	COG0556	nucleotide-excision repair
N1207_19205	COG4897	Protein conserved in bacteria
N1207_19210	COG0574	Belongs to the PEP-utilizing enzyme family
N1207_19210	COG3848	Pyruvate phosphate dikinase
N1207_19215	COG1309	transcriptional regulator
N1207_19220	COG2814	Major facilitator Superfamily
N1207_19225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N1207_19235	COG3409	Peptidoglycan-binding domain 1 protein
N1207_19235	COG0793	Belongs to the peptidase S41A family
N1207_19240	COG2177	Part of the ABC transporter FtsEX involved in
N1207_19245	COG2884	Cell division ATP-binding protein ftsE
N1207_19250	COG2010	Cytochrome c
N1207_19255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N1207_19265	COG0653	protein targeting
N1207_19270	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N1207_19285	COG1516	flagellar protein fliS
N1207_19290	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N1207_19295	COG1334	flagellar protein FlaG
N1207_19300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N1207_19305	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N1207_19310	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
N1207_19320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N1207_19325	COG4786	Flagellar basal body rod
N1207_19325	COG1256	bacterial-type flagellum assembly
N1207_19330	COG3418	PFAM FlgN family protein
N1207_19335	COG2747	anti-sigma28 factor FlgM
N1207_19345	COG1040	competence protein
N1207_19355	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
N1207_19360	COG1307	EDD domain protein, DegV family
N1207_19365	COG2197	response regulator
N1207_19370	COG4585	Histidine kinase
N1207_19375	COG1739	Uncharacterized protein family UPF0029
N1207_19380	COG1316	TRANSCRIPTIONal
N1207_19385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N1207_19390	COG0438	transferase activity, transferring glycosyl groups
N1207_19395	COG1215	transferase activity, transferring glycosyl groups
N1207_19400	COG3206	protein involved in exopolysaccharide biosynthesis
N1207_19405	COG3307	-O-antigen
N1207_19410	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N1207_19415	COG0438	transferase activity, transferring glycosyl groups
N1207_19415	COG0297	glycogen (starch) synthase activity
N1207_19420	COG2244	polysaccharide biosynthetic process
N1207_19435	COG0860	N-Acetylmuramoyl-L-alanine amidase
N1207_19435	COG2247	cell wall binding repeat
N1207_19440	COG2385	sporulation resulting in formation of a cellular spore
N1207_19440	COG2247	cell wall binding repeat
N1207_19450	COG1316	TRANSCRIPTIONal
N1207_19455	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N1207_19475	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N1207_19480	COG1134	teichoic acid transport
N1207_19485	COG1682	transport, permease protein
N1207_19490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N1207_19490	COG1215	transferase activity, transferring glycosyl groups
N1207_19495	COG0463	Glycosyl transferase, family 2
N1207_19540	COG4193	domain, Protein
N1207_19545	COG1482	cell wall glycoprotein biosynthetic process
N1207_19550	COG0697	spore germination
N1207_19555	COG0814	amino acid
N1207_19565	COG2814	Major facilitator Superfamily
N1207_19570	COG1316	TRANSCRIPTIONal
N1207_19575	COG0561	phosphatase activity
N1207_19580	COG0791	NLP P60 protein
N1207_19590	COG2843	Capsule synthesis protein
N1207_19600	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N1207_19605	COG1609	Transcriptional regulator
N1207_19610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N1207_19615	COG1869	D-ribose catabolic process
N1207_19620	COG1129	ABC transporter
N1207_19625	COG1172	Belongs to the binding-protein-dependent transport system permease family
N1207_19630	COG1879	ABC-type sugar transport system periplasmic component
N1207_19635	COG3103	Sh3 type 3 domain protein
N1207_19645	COG2249	NAD(P)H dehydrogenase (quinone) activity
N1207_19650	COG3527	Alpha-acetolactate decarboxylase
N1207_19655	COG0028	Belongs to the TPP enzyme family
N1207_19660	COG0583	DNA-binding transcription factor activity
N1207_19665	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N1207_19680	COG5337	Spore coat protein CotH
N1207_19690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N1207_19700	COG0405	Gamma-glutamyltransferase
N1207_19705	COG1522	sequence-specific DNA binding
N1207_19710	COG2059	Chromate
N1207_19715	COG2059	Chromate
N1207_19730	COG5444	nuclease activity
N1207_19750	COG3878	Protein conserved in bacteria
N1207_19755	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N1207_19760	COG4464	protein tyrosine phosphatase activity
N1207_19765	COG0489	protein tyrosine kinase activity
N1207_19770	COG3944	biosynthesis protein
N1207_19780	COG4715	Zinc finger, swim domain protein
N1207_19785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N1207_19790	COG0561	phosphatase activity
N1207_19795	COG1349	DNA-binding transcription factor activity
N1207_19800	COG0629	single-stranded DNA binding
N1207_19815	COG3764	Sortase (surface protein transpeptidase)
N1207_19825	COG3279	Response regulator of the LytR AlgR family
N1207_19835	COG0745	RESPONSE REGULATOR receiver
N1207_19835	COG2972	Histidine kinase
N1207_19840	COG1970	mechanosensitive ion channel activity
N1207_19845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N1207_19850	COG0457	Tetratricopeptide repeat
N1207_19855	COG4786	Flagellar basal body rod
N1207_19860	COG4786	Flagellar basal body rod
N1207_19865	COG1077	Cell shape determining protein MreB Mrl
N1207_19870	COG1609	Transcriptional regulator
N1207_19880	COG1846	Transcriptional regulator
N1207_19885	COG2814	Major facilitator Superfamily
N1207_19890	COG3420	alginic acid biosynthetic process
N1207_19895	COG1953	Uracil, thiamine, allantoin
N1207_19900	COG0477	Major facilitator Superfamily
N1207_19905	COG1335	isochorismatase
N1207_19915	COG0004	ammonium transporteR
N1207_19920	COG0347	Belongs to the P(II) protein family
N1207_19925	COG0671	phosphoesterase, PA-phosphatase related
N1207_19935	COG0739	heme binding
N1207_19940	COG1247	-acetyltransferase
N1207_19960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N1207_19965	COG0789	Transcriptional regulator
N1207_19975	COG2910	NAD(P)H-binding
N1207_19980	COG1959	2 iron, 2 sulfur cluster binding
N1207_19985	COG0804	urea catabolic process
N1207_19990	COG0832	Belongs to the urease beta subunit family
N1207_19995	COG0831	urea catabolic process
N1207_20010	COG3237	CsbD-like
N1207_20015	COG1994	Peptidase M50
N1207_20020	COG0457	Tetratricopeptide repeat
N1207_20025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N1207_20030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N1207_20040	COG2304	oxidoreductase activity
N1207_20050	COG2304	oxidoreductase activity
N1207_20055	COG2385	sporulation resulting in formation of a cellular spore
N1207_20060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N1207_20070	COG4836	Membrane
N1207_20080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N1207_20085	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N1207_20090	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N1207_20095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N1207_20100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N1207_20105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N1207_20115	COG0356	it plays a direct role in the translocation of protons across the membrane
N1207_20125	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N1207_20130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N1207_20135	COG4475	Protein of unknown function (DUF436)
N1207_20140	COG0698	ribose 5-phosphate isomerase
N1207_20145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N1207_20150	COG1971	Probably functions as a manganese efflux pump
N1207_20155	COG0009	L-threonylcarbamoyladenylate synthase
N1207_20160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N1207_20180	COG2890	protein-(glutamine-N5) methyltransferase activity
N1207_20185	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N1207_20190	COG0346	lactoylglutathione lyase activity
N1207_20195	COG0789	Transcriptional regulator
N1207_20200	COG0679	Auxin Efflux Carrier
N1207_20205	COG0281	malic enzyme
N1207_20210	COG1435	thymidine kinase activity
N1207_20220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N1207_20230	COG1494	fructose-1,6-bisphosphatase
N1207_20235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N1207_20240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N1207_20245	COG0191	fructose-bisphosphate aldolase activity
N1207_20250	COG2204	response regulator
N1207_20255	COG4821	SIS domain
N1207_20260	COG0504	CTP synthase activity
N1207_20265	COG3343	RNA polymerase activity
N1207_20270	COG1960	acyl-CoA dehydrogenase activity
N1207_20275	COG2181	nitrate reductase activity
N1207_20275	COG0247	lactate metabolic process
N1207_20280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N1207_20285	COG4294	response to UV
N1207_20295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N1207_20300	COG1132	(ABC) transporter
N1207_20305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N1207_20315	COG2181	nitrate reductase activity
N1207_20320	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
N1207_20325	COG1140	nitrate reductase beta subunit
N1207_20330	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
N1207_20335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N1207_20345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N1207_20350	COG2223	nitrite transmembrane transporter activity
N1207_20355	COG0018	arginyl-trna synthetase
N1207_20360	COG4506	Protein conserved in bacteria
N1207_20375	COG0535	radical SAM domain protein
N1207_20385	COG1131	(ABC) transporter
N1207_20390	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N1207_20395	COG0612	Peptidase, M16
N1207_20400	COG0612	Peptidase, M16
N1207_20410	COG3391	amine dehydrogenase activity
N1207_20415	COG3391	amine dehydrogenase activity
N1207_20420	COG0457	Tetratricopeptide repeat
N1207_20450	COG1131	(ABC) transporter
N1207_20460	COG0010	Belongs to the arginase family
N1207_20465	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N1207_20470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N1207_20485	COG1994	Peptidase M50
N1207_20490	COG1942	4-Oxalocrotonate Tautomerase
N1207_20495	COG1846	Transcriptional regulator
N1207_20500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N1207_20505	COG0477	Major facilitator Superfamily
N1207_20510	COG1959	2 iron, 2 sulfur cluster binding
N1207_20515	COG3465	dGTPase activity
N1207_20520	COG1078	dGTPase activity
N1207_20525	COG4844	belongs to the
N1207_20535	COG0697	spore germination
N1207_20540	COG0095	Lipoate-protein ligase
N1207_20545	COG0583	DNA-binding transcription factor activity
N1207_20550	COG0280	phosphate acetyltransferase
N1207_20555	COG3253	May function as heme-dependent peroxidase
N1207_20560	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_20565	COG0436	Aminotransferase
N1207_20570	COG2814	Major facilitator Superfamily
N1207_20575	COG0151	Belongs to the GarS family
N1207_20580	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_20585	COG1917	Cupin 2, conserved barrel domain protein
N1207_20590	COG0077	Prephenate dehydratase
N1207_20595	COG2814	Major facilitator Superfamily
N1207_20600	COG0833	amino acid
N1207_20605	COG4187	Peptidase family M20/M25/M40
N1207_20610	COG1012	belongs to the aldehyde dehydrogenase family
N1207_20615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N1207_20625	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N1207_20630	COG1091	dTDP-4-dehydrorhamnose reductase activity
N1207_20635	COG1088	dTDP-glucose 4,6-dehydratase activity
N1207_20640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
N1207_20645	COG3980	spore coat polysaccharide biosynthesis protein
N1207_20650	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
N1207_20655	COG2089	acid synthase
N1207_20660	COG0456	acetyltransferase
N1207_20665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N1207_20670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N1207_20675	COG0463	Glycosyl transferase, family 2
N1207_20685	COG2363	Small membrane protein
N1207_20690	COG2233	PERMEase
N1207_20700	COG1012	belongs to the aldehyde dehydrogenase family
N1207_20705	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N1207_20710	COG1216	Glycosyl transferase, family 2
N1207_20725	COG1695	Transcriptional regulator
N1207_20730	COG0351	phosphomethylpyrimidine kinase
N1207_20740	COG1621	beta-fructofuranosidase activity
N1207_20745	COG1263	PTS System
N1207_20745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_20750	COG2116	formate transmembrane transporter activity
N1207_20755	COG3711	transcriptional antiterminator
N1207_20765	COG1404	Belongs to the peptidase S8 family
N1207_20770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N1207_20775	COG0778	Nitroreductase
N1207_20780	COG0772	Belongs to the SEDS family
N1207_20790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N1207_20795	COG1845	cytochrome c oxidase, subunit III
N1207_20800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N1207_20805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N1207_20810	COG2261	transglycosylase associated protein
N1207_20815	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
N1207_20820	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
N1207_20825	COG2246	polysaccharide biosynthetic process
N1207_20830	COG1309	transcriptional regulator
N1207_20840	COG3162	membrane
N1207_20845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N1207_20850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N1207_20855	COG2837	iron assimilation
N1207_20860	COG2822	iron ion transport
N1207_20865	COG0672	)-iron permease
N1207_20870	COG0352	thiamine-phosphate diphosphorylase activity
N1207_20875	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
N1207_20880	COG0583	DNA-binding transcription factor activity
N1207_20885	COG1380	Effector of murein hydrolase LrgA
N1207_20890	COG1346	cytolysis
N1207_20895	COG2814	Major facilitator Superfamily
N1207_20900	COG4895	conserved protein (DUF2196)
N1207_20905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N1207_20910	COG0346	lactoylglutathione lyase activity
N1207_20935	COG1404	Belongs to the peptidase S8 family
N1207_20940	COG1263	PTS System
N1207_20940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_20945	COG3711	transcriptional antiterminator
N1207_20950	COG1442	glycosyl transferase family 8
N1207_20955	COG5522	Integral membrane protein (intg_mem_TP0381)
N1207_20960	COG1846	Transcriptional regulator
N1207_20965	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N1207_20970	COG2234	aminopeptidase activity
N1207_20985	COG2814	Major facilitator Superfamily
N1207_20990	COG2357	RelA SpoT domain protein
N1207_20995	COG1575	Belongs to the MenA family. Type 1 subfamily
N1207_21010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N1207_21015	COG1696	Membrane protein involved in D-alanine export
N1207_21020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N1207_21025	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
N1207_21030	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
N1207_21035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N1207_21040	COG1486	melibiose metabolic process
N1207_21045	COG1447	Phosphotransferase system cellobiose-specific component IIA
N1207_21050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N1207_21055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N1207_21060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N1207_21060	COG3711	transcriptional antiterminator
N1207_21070	COG2094	Belongs to the DNA glycosylase MPG family
N1207_21075	COG0753	catalase activity
N1207_21080	COG2814	Major facilitator Superfamily
N1207_21085	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N1207_21090	COG1131	(ABC) transporter
N1207_21110	COG1595	DNA-templated transcription, initiation
N1207_21115	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N1207_21120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N1207_21125	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N1207_21130	COG4988	ABC transporter
N1207_21135	COG1294	oxidase, subunit
N1207_21140	COG1271	oxidase subunit
N1207_21145	COG3493	citrate carrier protein
N1207_21150	COG0501	Belongs to the peptidase M48B family
N1207_21160	COG0726	polysaccharide deacetylase
N1207_21175	COG3842	ATPase activity
N1207_21180	COG2508	Transcriptional regulator
N1207_21185	COG1012	belongs to the aldehyde dehydrogenase family
N1207_21190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N1207_21200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N1207_21205	COG1881	PFAM PEBP family protein
N1207_21210	COG0583	DNA-binding transcription factor activity
N1207_21220	COG4585	Histidine kinase
N1207_21225	COG2197	response regulator
N1207_21230	COG2195	Cleaves the N-terminal amino acid of tripeptides
N1207_21245	COG4894	glucomannan catabolic process
N1207_21250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N1207_21255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N1207_21260	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_21265	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N1207_21270	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N1207_21275	COG2610	gluconate transmembrane transporter activity
N1207_21280	COG0500	methyltransferase
N1207_21285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N1207_21300	COG0693	protein deglycase activity
N1207_21300	COG0753	catalase activity
N1207_21305	COG2851	Citrate transporter
N1207_21310	COG2273	Hydrolase Family 16
N1207_21315	COG3711	transcriptional antiterminator
N1207_21325	COG2270	Major facilitator Superfamily
N1207_21330	COG0513	Belongs to the DEAD box helicase family
N1207_21335	COG2755	lipolytic protein G-D-S-L family
N1207_21335	COG3401	FG-GAP repeat protein
N1207_21380	COG3209	COG3209 Rhs family protein
N1207_21385	COG0697	spore germination
N1207_21390	COG0589	response to stress
N1207_21395	COG2723	6-phospho-beta-galactosidase activity
N1207_21400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_21400	COG2190	(PTS) system
N1207_21400	COG1263	PTS System
N1207_21445	COG3507	Belongs to the glycosyl hydrolase 43 family
N1207_21460	COG2986	histidine ammonia-lyase
N1207_21465	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N1207_21470	COG1228	amidohydrolase
N1207_21475	COG0010	Belongs to the arginase family
N1207_21480	COG0833	amino acid
N1207_21485	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N1207_21490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N1207_21495	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N1207_21500	COG2390	Transcriptional regulator
N1207_21510	COG3192	ethanolamine utilization protein
N1207_21515	COG2079	MmgE PrpD family protein
N1207_21520	COG1473	amidohydrolase
N1207_21525	COG1126	abc transporter atp-binding protein
N1207_21530	COG0765	amino acid transport
N1207_21535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N1207_21540	COG0456	acetyltransferase
N1207_21545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N1207_21550	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
N1207_21555	COG0561	phosphatase activity
N1207_21585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N1207_21590	COG5294	Protein conserved in bacteria
N1207_21595	COG0577	efflux transmembrane transporter activity
N1207_21600	COG1136	(ABC) transporter
N1207_21605	COG2205	protein histidine kinase activity
N1207_21610	COG0745	RESPONSE REGULATOR receiver
N1207_21615	COG0191	fructose-bisphosphate aldolase activity
N1207_21620	COG1082	Xylose isomerase domain protein TIM barrel
N1207_21625	COG1082	Xylose isomerase domain protein TIM barrel
N1207_21630	COG0673	inositol 2-dehydrogenase activity
N1207_21635	COG2814	Major facilitator Superfamily
N1207_21640	COG1082	Xylose isomerase domain protein TIM barrel
N1207_21645	COG3962	Belongs to the TPP enzyme family
N1207_21650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N1207_21660	COG1012	belongs to the aldehyde dehydrogenase family
N1207_21665	COG1349	DNA-binding transcription factor activity
N1207_21670	COG0667	Aldo Keto reductase
N1207_21685	COG2814	Major facilitator Superfamily
N1207_21690	COG0326	Molecular chaperone. Has ATPase activity
N1207_21700	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_21725	COG1309	transcriptional regulator
N1207_21730	COG1012	belongs to the aldehyde dehydrogenase family
N1207_21735	COG1714	RDD family
N1207_21740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N1207_21750	COG1714	RDD family
N1207_21755	COG2311	Membrane
N1207_21760	COG1917	Cupin 2, conserved barrel domain protein
N1207_21765	COG1309	transcriptional regulator
N1207_21770	COG1028	Short-chain dehydrogenase reductase Sdr
N1207_21775	COG1846	Transcriptional regulator
N1207_21780	COG1380	Effector of murein hydrolase LrgA
N1207_21785	COG1346	cytolysis
N1207_21790	COG5039	Polysaccharide pyruvyl transferase
N1207_21795	COG1929	Belongs to the glycerate kinase type-1 family
N1207_21800	COG1802	Transcriptional regulator
N1207_21805	COG1070	Carbohydrate kinase
N1207_21810	COG2610	gluconate transmembrane transporter activity
N1207_21815	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N1207_21820	COG0450	alkyl hydroperoxide reductase
N1207_21825	COG3634	alkyl hydroperoxide reductase activity
N1207_21845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N1207_21845	COG1263	PTS System
N1207_21850	COG2188	Transcriptional regulator
N1207_21865	COG1131	(ABC) transporter
N1207_21870	COG1994	Peptidase M50
N1207_21875	COG0535	radical SAM domain protein
N1207_21885	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
N1207_21895	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N1207_21910	COG1063	alcohol dehydrogenase
N1207_21930	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
N1207_21935	COG0456	acetyltransferase
N1207_21940	COG0457	Tetratricopeptide repeat
N1207_21950	COG0010	Belongs to the arginase family
N1207_21955	COG0833	amino acid
N1207_21960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N1207_21965	COG3829	transcription factor binding
N1207_21980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N1207_21985	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N1207_21990	COG4853	Protein conserved in bacteria
N1207_21995	COG4863	YycH protein
N1207_22000	COG5002	protein histidine kinase activity
N1207_22005	COG0745	RESPONSE REGULATOR receiver
N1207_22035	COG0346	lactoylglutathione lyase activity
N1207_22040	COG0305	Participates in initiation and elongation during chromosome replication
N1207_22055	COG3093	addiction module antidote protein HigA
N1207_22060	COG2807	transmembrane transport
N1207_22065	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N1207_22070	COG0359	binds to the 23S rRNA
N1207_22075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
N1207_22080	COG4241	membrane
N1207_22090	COG5577	PFAM Coat F domain
N1207_22095	COG1733	regulation of RNA biosynthetic process
N1207_22100	COG1227	inorganic diphosphatase activity
N1207_22115	COG2271	Major facilitator Superfamily
N1207_22120	COG0789	Transcriptional regulator
N1207_22120	COG4978	Transcriptional regulator
N1207_22140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N1207_22145	COG1846	Transcriptional regulator
N1207_22150	COG2153	protein acetylation
N1207_22155	COG2364	Membrane
N1207_22160	COG0456	acetyltransferase
N1207_22165	COG2315	Protein conserved in bacteria
N1207_22170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N1207_22190	COG0789	Transcriptional regulator
N1207_22195	COG0697	spore germination
N1207_22200	COG1331	Highly conserved protein containing a thioredoxin domain
N1207_22205	COG1266	CAAX protease self-immunity
N1207_22210	COG0477	Major facilitator Superfamily
N1207_22210	COG2814	Major facilitator Superfamily
N1207_22215	COG0110	maltose O-acetyltransferase activity
N1207_22220	COG0346	lactoylglutathione lyase activity
N1207_22225	COG1609	Transcriptional regulator
N1207_22230	COG0708	Exodeoxyribonuclease III
N1207_22235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N1207_22240	COG0629	single-stranded DNA binding
N1207_22245	COG0360	Binds together with S18 to 16S ribosomal RNA
N1207_22250	COG0012	GTP binding
N1207_22255	COG0243	molybdopterin cofactor binding
N1207_22260	COG4481	Protein conserved in bacteria
N1207_22265	COG3949	Membrane
N1207_22275	COG1475	DNA binding
N1207_22280	COG1192	Involved in chromosome partitioning
N1207_22290	COG1475	DNA binding
N1207_22295	COG0357	Ribosomal RNA small subunit methyltransferase G
N1207_22300	COG0445	tRNA wobble uridine modification
N1207_22305	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N1207_22310	COG1847	R3H domain protein
N1207_22315	COG0706	membrane insertase activity
N1207_22320	COG0594	ribonuclease P activity